CNX65_RS25320 2160c3dc6a9d305622b3444f641d7c21 128 Gene3D G3DSA:3.30.750.24 3 111 4.8E-25 T 28-03-2018 IPR002645 STAS domain CNX65_RS25320 2160c3dc6a9d305622b3444f641d7c21 128 SUPERFAMILY SSF52091 9 109 4.71E-23 T 28-03-2018 IPR002645 STAS domain CNX65_RS25320 2160c3dc6a9d305622b3444f641d7c21 128 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 105 1.4E-18 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS25320 2160c3dc6a9d305622b3444f641d7c21 128 Pfam PF13466 STAS domain 17 96 1.3E-15 T 28-03-2018 IPR002645 STAS domain CNX65_RS09845 7a3a3494aa5214c9e9aee7471fb59b23 203 SUPERFAMILY SSF46689 14 75 6.48E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS09845 7a3a3494aa5214c9e9aee7471fb59b23 203 Gene3D G3DSA:1.10.357.10 68 203 2.6E-13 T 28-03-2018 CNX65_RS09845 7a3a3494aa5214c9e9aee7471fb59b23 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 63 5.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS09845 7a3a3494aa5214c9e9aee7471fb59b23 203 SUPERFAMILY SSF48498 83 203 4.45E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS09845 7a3a3494aa5214c9e9aee7471fb59b23 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 7.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS09845 7a3a3494aa5214c9e9aee7471fb59b23 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 7.8E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS09845 7a3a3494aa5214c9e9aee7471fb59b23 203 Gene3D G3DSA:1.10.10.60 14 67 1.1E-17 T 28-03-2018 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 58 656 33.095 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 SMART SM00863 170 226 2.2E-20 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 345 551 1.2E-35 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 SUPERFAMILY SSF55681 250 547 9.19E-92 T 28-03-2018 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Gene3D G3DSA:3.30.930.10 230 553 4.0E-104 T 28-03-2018 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Gene3D G3DSA:3.30.54.20 136 183 3.3E-15 T 28-03-2018 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Gene3D G3DSA:3.40.50.800 554 665 2.9E-23 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 PRINTS PR01047 Threonyl-tRNA synthetase signature 529 542 1.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 PRINTS PR01047 Threonyl-tRNA synthetase signature 556 568 1.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 PRINTS PR01047 Threonyl-tRNA synthetase signature 486 514 1.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 PRINTS PR01047 Threonyl-tRNA synthetase signature 383 406 1.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 PRINTS PR01047 Threonyl-tRNA synthetase signature 350 378 1.7E-52 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Gene3D G3DSA:3.30.980.10 59 135 1.0E-16 T 28-03-2018 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Pfam PF03129 Anticodon binding domain 563 650 2.9E-17 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Gene3D G3DSA:3.30.980.10 184 229 4.6E-14 T 28-03-2018 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 SUPERFAMILY SSF52954 551 657 2.87E-29 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 SUPERFAMILY SSF55186 56 247 4.58E-49 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 64 650 3.6E-195 T 28-03-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 CNX65_RS10645 d9229f04949f7a0d8d5be2911192a9a7 668 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 181 226 1.1E-12 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CNX65_RS27580 fe5bd08eaee240bbe52440fa998450f4 397 Gene3D G3DSA:3.40.50.2300 174 303 3.8E-29 T 28-03-2018 CNX65_RS27580 fe5bd08eaee240bbe52440fa998450f4 397 Pfam PF13458 Periplasmic binding protein 44 382 8.9E-60 T 28-03-2018 IPR028081 Leucine-binding protein domain CNX65_RS27580 fe5bd08eaee240bbe52440fa998450f4 397 Gene3D G3DSA:3.40.50.2300 304 372 2.4E-5 T 28-03-2018 CNX65_RS27580 fe5bd08eaee240bbe52440fa998450f4 397 SUPERFAMILY SSF53822 43 386 9.08E-80 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS27580 fe5bd08eaee240bbe52440fa998450f4 397 Gene3D G3DSA:3.40.50.2300 44 173 8.2E-21 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 349 456 1.7E-23 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 SUPERFAMILY SSF55424 347 461 1.53E-27 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 9.4E-37 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 9.4E-37 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 9.4E-37 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 9.4E-37 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 9.4E-37 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PIRSF PIRSF000350 1 457 4.5E-81 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 35 50 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 2.8E-54 T 28-03-2018 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 Gene3D G3DSA:3.50.50.60 281 353 1.4E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 328 2.9E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 Gene3D G3DSA:3.30.390.30 354 462 1.9E-28 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 Gene3D G3DSA:3.50.50.60 161 280 3.5E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 Gene3D G3DSA:3.50.50.60 1 160 2.6E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 SUPERFAMILY SSF51905 3 98 6.33E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31450 b23fecc42866f6ee3f47653841aabf13 467 SUPERFAMILY SSF51905 129 337 6.33E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS12675 d7e80e1e65e10198c302fe992ced78b9 628 Gene3D G3DSA:1.10.530.10 5 211 9.9E-19 T 28-03-2018 CNX65_RS12675 d7e80e1e65e10198c302fe992ced78b9 628 SMART SM00644 257 392 5.6E-40 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS12675 d7e80e1e65e10198c302fe992ced78b9 628 SUPERFAMILY SSF53955 33 96 3.09E-5 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS12675 d7e80e1e65e10198c302fe992ced78b9 628 Gene3D G3DSA:3.40.80.10 236 409 9.9E-35 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS12675 d7e80e1e65e10198c302fe992ced78b9 628 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 265 393 4.9E-27 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS12675 d7e80e1e65e10198c302fe992ced78b9 628 SUPERFAMILY SSF55846 244 408 3.8E-39 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SUPERFAMILY SSF55785 240 367 1.37E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SUPERFAMILY SSF55785 492 621 1.73E-20 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Pfam PF08448 PAS fold 516 625 6.9E-11 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Gene3D G3DSA:3.30.450.20 21 99 0.0015 T 28-03-2018 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Gene3D G3DSA:3.20.20.450 802 1057 2.6E-85 T 28-03-2018 IPR001633 EAL domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SUPERFAMILY SSF55785 366 493 2.79E-24 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 504 630 7.7E-20 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 385 500 8.0E-10 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 124 250 6.0E-8 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SUPERFAMILY SSF141868 808 1053 3.27E-78 T 28-03-2018 IPR001633 EAL domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SUPERFAMILY SSF55073 639 792 4.19E-38 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Pfam PF08447 PAS fold 404 484 5.3E-14 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Pfam PF08447 PAS fold 151 235 1.2E-9 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Pfam PF00563 EAL domain 809 1043 6.2E-65 T 28-03-2018 IPR001633 EAL domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00086 327 369 120.0 T 28-03-2018 IPR001610 PAC motif CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00086 454 495 0.0042 T 28-03-2018 IPR001610 PAC motif CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00086 201 243 1.0E-4 T 28-03-2018 IPR001610 PAC motif CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00086 582 623 0.92 T 28-03-2018 IPR001610 PAC motif CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 630 792 2.5E-33 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Pfam PF00990 Diguanylate cyclase, GGDEF domain 634 787 5.6E-34 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Pfam PF13426 PAS domain 36 81 0.38 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Gene3D G3DSA:3.30.450.20 253 377 3.7E-15 T 28-03-2018 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Gene3D G3DSA:3.30.450.20 378 495 2.9E-31 T 28-03-2018 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Gene3D G3DSA:3.30.450.20 100 252 2.1E-26 T 28-03-2018 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Gene3D G3DSA:3.30.450.20 496 639 3.1E-26 T 28-03-2018 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00267 623 793 1.1E-50 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 Gene3D G3DSA:3.30.70.270 640 801 8.7E-51 T 28-03-2018 CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SUPERFAMILY SSF55785 112 241 5.76E-18 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00091 19 89 31.0 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00091 127 195 4.0 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00091 381 448 2.7E-5 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00091 255 321 90.0 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00091 507 573 4.7E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS30915 682368e6072efdffa43ceb59629245f9 1064 SMART SM00052 803 1048 5.3E-89 T 28-03-2018 IPR001633 EAL domain CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 SMART SM00861 4 178 8.0E-24 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 SUPERFAMILY SSF51230 391 476 1.44E-12 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Pfam PF02779 Transketolase, pyrimidine binding domain 7 177 2.8E-22 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 SUPERFAMILY SSF52777 518 748 1.42E-42 T 28-03-2018 CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Gene3D G3DSA:3.40.50.920 200 333 5.3E-22 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Gene3D G3DSA:3.30.559.10 512 754 5.3E-40 T 28-03-2018 CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 SUPERFAMILY SSF52518 5 181 1.39E-36 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Gene3D G3DSA:2.40.50.100 389 464 1.7E-6 T 28-03-2018 CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Pfam PF02780 Transketolase, C-terminal domain 212 324 2.8E-15 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 529 749 6.5E-37 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 414 443 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Pfam PF00364 Biotin-requiring enzyme 392 462 1.6E-6 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 SUPERFAMILY SSF52922 211 332 5.37E-21 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS18370 33ef61e0dd022406bc2b60c39075789c 754 Gene3D G3DSA:3.40.50.970 3 188 1.9E-33 T 28-03-2018 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 Gene3D G3DSA:1.20.20.10 6 73 3.1E-19 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 Pfam PF00137 ATP synthase subunit C 15 71 2.5E-12 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 18 72 4.4E-20 T 28-03-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 SUPERFAMILY SSF81333 12 72 7.45E-18 T 28-03-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 Hamap MF_01396 ATP synthase subunit c [atpH]. 8 73 15.209 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 PRINTS PR00124 ATP synthase C subunit signature 31 46 2.6E-18 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 PRINTS PR00124 ATP synthase C subunit signature 48 73 2.6E-18 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 PRINTS PR00124 ATP synthase C subunit signature 10 29 2.6E-18 T 28-03-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30220 877d4cd43b151bb5b5b0186396c337bc 73 ProSitePatterns PS00605 ATP synthase c subunit signature. 38 59 - T 28-03-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS34935 792d81c7ed61c13f05cb1ad07214c859 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 8.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34935 792d81c7ed61c13f05cb1ad07214c859 248 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 8.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34935 792d81c7ed61c13f05cb1ad07214c859 248 SUPERFAMILY SSF48498 92 241 1.6E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS34935 792d81c7ed61c13f05cb1ad07214c859 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 1.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34935 792d81c7ed61c13f05cb1ad07214c859 248 Gene3D G3DSA:1.10.10.60 3 65 3.6E-17 T 28-03-2018 CNX65_RS34935 792d81c7ed61c13f05cb1ad07214c859 248 Gene3D G3DSA:1.10.357.10 66 246 3.0E-24 T 28-03-2018 CNX65_RS34935 792d81c7ed61c13f05cb1ad07214c859 248 SUPERFAMILY SSF46689 6 79 1.9E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS30925 ad46826165b26bc5116268b6859941f8 198 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 1 176 3.0E-61 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CNX65_RS30925 ad46826165b26bc5116268b6859941f8 198 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 6 174 9.2E-57 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CNX65_RS30925 ad46826165b26bc5116268b6859941f8 198 SUPERFAMILY SSF51182 1 195 4.72E-68 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS30925 ad46826165b26bc5116268b6859941f8 198 Gene3D G3DSA:2.60.120.10 1 189 5.9E-62 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS14785 7fcae72c3afde5c831a5f69d6365751d 680 SUPERFAMILY SSF52540 415 653 6.05E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14785 7fcae72c3afde5c831a5f69d6365751d 680 SMART SM00382 460 592 5.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS14785 7fcae72c3afde5c831a5f69d6365751d 680 Gene3D G3DSA:3.40.50.300 407 603 3.9E-28 T 28-03-2018 CNX65_RS14785 7fcae72c3afde5c831a5f69d6365751d 680 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 465 589 1.1E-22 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 19 410 1.5E-143 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 Gene3D G3DSA:3.40.605.10 1 245 1.8E-44 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 SUPERFAMILY SSF53720 10 420 1.44E-115 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 327 348 - T 28-03-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 11 420 41.858 T 28-03-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 Pfam PF00171 Aldehyde dehydrogenase family 5 290 2.5E-18 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 Gene3D G3DSA:3.40.605.10 246 422 7.6E-36 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS05950 517d537c57b12e2b0c3a8cf807137c88 423 PIRSF PIRSF000151 4 421 2.4E-171 T 28-03-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 SUPERFAMILY SSF55347 131 339 3.02E-65 T 28-03-2018 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 Gene3D G3DSA:3.30.360.10 143 335 1.3E-77 T 28-03-2018 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 Gene3D G3DSA:3.40.50.720 6 142 2.1E-29 T 28-03-2018 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 4 352 32.033 T 28-03-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 120 1.0E-28 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 351 3.8E-112 T 28-03-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 142 338 3.3E-45 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 PIRSF PIRSF000148 5 355 4.0E-107 T 28-03-2018 CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 SUPERFAMILY SSF51735 7 158 4.31E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS01020 7fa1b41e46f29b818ddd640b665f5360 355 SMART SM00859 6 122 8.8E-36 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 Gene3D G3DSA:1.20.144.10 8 198 2.0E-27 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 SUPERFAMILY SSF111331 205 480 3.27E-43 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 Gene3D G3DSA:3.40.50.10330 199 321 5.9E-10 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 SMART SM00014 68 177 3.3E-21 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 Pfam PF00781 Diacylglycerol kinase catalytic domain 246 310 1.7E-9 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 SUPERFAMILY SSF48317 8 188 2.09E-35 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 SMART SM00046 204 322 2.8E-4 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CNX65_RS11425 52f5891cdf383875ca0871cc9922c16d 482 Pfam PF01569 PAP2 superfamily 72 182 2.8E-15 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS20340 b0d58c425a70ee88079ff2318eb38114 173 Gene3D G3DSA:3.40.630.30 3 173 3.7E-36 T 28-03-2018 CNX65_RS20340 b0d58c425a70ee88079ff2318eb38114 173 SUPERFAMILY SSF55729 6 167 1.45E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS20340 b0d58c425a70ee88079ff2318eb38114 173 Pfam PF13420 Acetyltransferase (GNAT) domain 8 160 2.5E-22 T 28-03-2018 CNX65_RS12655 6407d82e15fb09e0941f304ab22b66b3 380 Gene3D G3DSA:3.40.50.2000 203 364 3.9E-36 T 28-03-2018 CNX65_RS12655 6407d82e15fb09e0941f304ab22b66b3 380 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 10 378 4.4E-50 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CNX65_RS12655 6407d82e15fb09e0941f304ab22b66b3 380 Gene3D G3DSA:3.40.50.2000 3 201 7.4E-25 T 28-03-2018 CNX65_RS12655 6407d82e15fb09e0941f304ab22b66b3 380 SUPERFAMILY SSF53756 3 379 3.37E-69 T 28-03-2018 CNX65_RS12655 6407d82e15fb09e0941f304ab22b66b3 380 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 216 346 2.3E-13 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CNX65_RS05335 fcc44819a7e9238d13e865e370064ae0 149 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 5 130 1.0E-34 T 28-03-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 CNX65_RS05335 fcc44819a7e9238d13e865e370064ae0 149 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 4 144 4.7E-33 T 28-03-2018 IPR002178 PTS EIIA type-2 domain CNX65_RS05335 fcc44819a7e9238d13e865e370064ae0 149 SUPERFAMILY SSF55804 2 143 7.19E-35 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CNX65_RS05335 fcc44819a7e9238d13e865e370064ae0 149 Gene3D G3DSA:3.40.930.10 1 147 1.1E-37 T 28-03-2018 IPR016152 Phosphotransferase/anion transporter GO:0005215|GO:0006810 Reactome: R-HSA-425381 CNX65_RS00615 eb78109c522411c2fd9e05d052295243 273 Gene3D G3DSA:3.40.50.1000 1 273 1.5E-38 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS00615 eb78109c522411c2fd9e05d052295243 273 SUPERFAMILY SSF56784 3 273 9.32E-55 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS00615 eb78109c522411c2fd9e05d052295243 273 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 269 1.5E-47 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS00615 eb78109c522411c2fd9e05d052295243 273 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 7 269 3.0E-42 T 28-03-2018 IPR000150 Cof family GO:0016787 CNX65_RS30360 cde18fa9c31f4bf58ef6d441641126ac 783 Pfam PF13476 AAA domain 57 105 9.9E-10 T 28-03-2018 CNX65_RS30360 cde18fa9c31f4bf58ef6d441641126ac 783 Gene3D G3DSA:3.40.50.300 51 669 1.3E-29 T 28-03-2018 CNX65_RS30360 cde18fa9c31f4bf58ef6d441641126ac 783 SUPERFAMILY SSF52540 51 252 2.29E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30360 cde18fa9c31f4bf58ef6d441641126ac 783 SUPERFAMILY SSF52540 450 630 2.29E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34020 1a3118e629288fb4cf9bbae43ced7472 295 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 10 286 8.4E-72 T 28-03-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 CNX65_RS34020 1a3118e629288fb4cf9bbae43ced7472 295 SUPERFAMILY SSF56104 5 289 2.98E-98 T 28-03-2018 CNX65_RS34020 1a3118e629288fb4cf9bbae43ced7472 295 ProSitePatterns PS01058 SAICAR synthetase signature 2. 194 202 - T 28-03-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS34020 1a3118e629288fb4cf9bbae43ced7472 295 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 7 286 24.296 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS34020 1a3118e629288fb4cf9bbae43ced7472 295 Pfam PF01259 SAICAR synthetase 10 259 9.5E-101 T 28-03-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS34020 1a3118e629288fb4cf9bbae43ced7472 295 Gene3D G3DSA:3.30.200.20 5 102 3.2E-34 T 28-03-2018 CNX65_RS34020 1a3118e629288fb4cf9bbae43ced7472 295 Gene3D G3DSA:3.30.470.20 103 238 1.3E-55 T 28-03-2018 CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 Gene3D G3DSA:1.20.1610.10 509 659 6.1E-45 T 28-03-2018 CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 43 797 1.8E-140 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 Gene3D G3DSA:2.70.98.10 43 378 1.3E-91 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 Pfam PF07971 Glycosyl hydrolase family 92 292 792 1.7E-152 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 SUPERFAMILY SSF48208 326 495 2.21E-14 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 SUPERFAMILY SSF48208 528 776 2.21E-14 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 Gene3D G3DSA:3.30.2080.10 660 806 2.1E-52 T 28-03-2018 CNX65_RS18825 2a32e134b011070a8fb8c04179ce2f3b 852 Gene3D G3DSA:1.20.1050.60 403 497 1.3E-17 T 28-03-2018 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 Gene3D G3DSA:3.40.1010.10 162 286 1.2E-32 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 Gene3D G3DSA:3.40.50.720 6 133 1.5E-16 T 28-03-2018 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 164 397 5.1E-77 T 28-03-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0006779|GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 12 134 7.3E-21 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 SUPERFAMILY SSF51735 6 108 4.72E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 164 374 1.2E-47 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 PIRSF PIRSF036426 4 160 3.1E-32 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 PIRSF PIRSF036426 147 405 1.3E-87 T 28-03-2018 IPR012409 Sirohaem synthase GO:0004851|GO:0009236|GO:0019354|GO:0043115|GO:0051266|GO:0051287|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 SUPERFAMILY SSF53790 162 398 1.19E-68 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 Gene3D G3DSA:3.30.950.10 287 404 2.3E-37 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28720 02b5ea25a97969850cd002493880fa06 405 Pfam PF13241 Putative NAD(P)-binding 11 118 5.2E-24 T 28-03-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0043115|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 Gene3D G3DSA:3.50.50.60 200 391 3.8E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.9E-6 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 186 211 1.9E-6 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 149 158 1.9E-6 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 Gene3D G3DSA:3.50.50.60 2 199 2.9E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 SUPERFAMILY SSF51905 233 383 1.04E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 SUPERFAMILY SSF51905 132 198 1.04E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.3E-12 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 301 317 6.3E-12 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 331 353 6.3E-12 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.3E-12 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 186 204 6.3E-12 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 223 6.6E-32 T 28-03-2018 CNX65_RS09175 47e72170e27cdefbc6930c987e797ccc 519 SUPERFAMILY SSF51905 5 233 5.44E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 206 216 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 Gene3D G3DSA:3.30.70.80 54 138 4.4E-16 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 Gene3D G3DSA:3.40.50.200 139 417 2.6E-73 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 171 182 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 185 9.5E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 215 9.5E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 PRINTS PR00723 Subtilisin serine protease family (S8) signature 358 374 9.5E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 359 369 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 SUPERFAMILY SSF54897 60 133 1.13E-8 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 Pfam PF00082 Subtilase family 167 396 5.6E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS18985 7efffb3ca98122e912caba78d1a263e4 539 SUPERFAMILY SSF52743 143 402 1.3E-70 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS32925 a7dc09395fc05b87ffd5d8672df1a6e8 182 Gene3D G3DSA:3.40.50.700 12 170 4.3E-45 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32925 a7dc09395fc05b87ffd5d8672df1a6e8 182 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 37 145 5.2E-25 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32925 a7dc09395fc05b87ffd5d8672df1a6e8 182 ProSitePatterns PS01150 Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. 118 134 - T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32925 a7dc09395fc05b87ffd5d8672df1a6e8 182 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 11 152 1.0E-71 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32925 a7dc09395fc05b87ffd5d8672df1a6e8 182 SUPERFAMILY SSF56770 9 154 3.4E-68 T 28-03-2018 CNX65_RS32925 a7dc09395fc05b87ffd5d8672df1a6e8 182 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 1 151 43.942 T 28-03-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 SUPERFAMILY SSF52540 358 639 1.97E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 427 631 3.8E-20 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 Pfam PF07497 Rho termination factor, RNA-binding domain 321 396 1.6E-28 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 SMART SM00959 42 84 6.7E-11 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 SMART SM00357 322 389 8.5E-6 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 SUPERFAMILY SSF50249 321 396 8.22E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 Hamap MF_01884 Transcription termination factor Rho [rho]. 314 687 196.211 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 Gene3D G3DSA:3.40.50.300 386 635 2.2E-50 T 28-03-2018 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 SUPERFAMILY SSF68912 42 80 9.02E-5 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 SMART SM00382 438 623 1.5E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 Pfam PF07498 Rho termination factor, N-terminal domain 43 79 4.6E-10 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 Gene3D G3DSA:2.40.50.140 39 385 6.3E-42 T 28-03-2018 CNX65_RS30285 8258e7ba9d8d678c0cf64513ecbff0c2 694 TIGRFAM TIGR00767 rho: transcription termination factor Rho 42 685 1.5E-195 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CNX65_RS10550 d58b06e602e26fe8db42f06120d3b713 315 Gene3D G3DSA:2.120.10.30 38 145 9.2E-8 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS10550 d58b06e602e26fe8db42f06120d3b713 315 SUPERFAMILY SSF63829 43 295 5.56E-23 T 28-03-2018 CNX65_RS10550 d58b06e602e26fe8db42f06120d3b713 315 Gene3D G3DSA:2.130.10.10 146 296 1.4E-9 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 SUPERFAMILY SSF47384 353 435 6.87E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 Pfam PF00672 HAMP domain 318 362 7.8E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 Gene3D G3DSA:1.10.287.130 360 429 5.9E-11 T 28-03-2018 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 480 589 3.7E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 SMART SM00387 479 591 1.3E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 544 1.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 530 1.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 569 1.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 588 1.5E-21 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 Pfam PF00512 His Kinase A (phospho-acceptor) domain 374 434 1.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 Gene3D G3DSA:3.30.565.10 451 594 1.6E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 SUPERFAMILY SSF158472 318 362 1.44E-7 T 28-03-2018 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 SMART SM00388 370 434 3.7E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 SMART SM00304 317 369 8.5E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS20365 d818429918b8d21188731976e49b0f87 594 SUPERFAMILY SSF55874 423 589 6.42E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 150 24.684 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 Gene3D G3DSA:3.40.5.10 2 49 2.0E-20 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 SUPERFAMILY SSF55653 58 148 2.49E-21 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 46 7.2E-21 T 28-03-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 148 3.4E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 149 7.3E-35 T 28-03-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 SUPERFAMILY SSF55658 1 56 1.5E-17 T 28-03-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal CNX65_RS34795 db24d37a46d3da0bbbb697698ac73cb2 151 Gene3D G3DSA:3.10.430.100 63 149 1.2E-24 T 28-03-2018 IPR020069 Ribosomal protein L9, C-terminal CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 Gene3D G3DSA:1.10.10.10 816 868 4.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 SUPERFAMILY SSF48452 516 612 1.42E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 SMART SM00421 805 862 8.3E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 Gene3D G3DSA:1.10.10.10 208 283 2.7E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 Gene3D G3DSA:1.25.40.10 284 599 1.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 838 850 1.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 808 822 1.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 822 838 1.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 SUPERFAMILY SSF52540 7 188 1.09E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 SMART SM00382 9 195 1.9E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 Pfam PF00196 Bacterial regulatory proteins, luxR family 807 858 8.0E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 Gene3D G3DSA:1.25.40.10 600 815 1.9E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 SUPERFAMILY SSF46894 802 860 1.73E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS15285 097f911feb29735ca41ea9684bde6875 890 Gene3D G3DSA:3.40.50.300 1 163 3.6E-8 T 28-03-2018 CNX65_RS14570 08129d261e1e082bb37a21ea5eeac746 295 Gene3D G3DSA:3.40.50.1110 38 288 1.4E-34 T 28-03-2018 CNX65_RS14570 08129d261e1e082bb37a21ea5eeac746 295 SUPERFAMILY SSF52266 41 288 6.16E-59 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS14570 08129d261e1e082bb37a21ea5eeac746 295 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 45 280 1.5E-27 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SUPERFAMILY SSF52540 270 543 1.02E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Gene3D G3DSA:3.40.50.300 271 436 2.7E-14 T 28-03-2018 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Gene3D G3DSA:1.10.150.200 752 817 4.1E-7 T 28-03-2018 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SMART SM01043 108 244 1.1E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 PRINTS PR00364 Disease resistance protein signature 384 398 1.0E-7 T 28-03-2018 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 PRINTS PR00364 Disease resistance protein signature 472 486 1.0E-7 T 28-03-2018 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 PRINTS PR00364 Disease resistance protein signature 304 319 1.0E-7 T 28-03-2018 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Gene3D G3DSA:1.25.40.10 103 265 1.5E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Pfam PF03704 Bacterial transcriptional activator domain 103 244 5.8E-38 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SUPERFAMILY SSF48452 747 925 2.36E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SMART SM00028 808 841 250.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SMART SM00028 768 801 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SMART SM00028 848 881 19.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SMART SM00862 23 101 1.1E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Gene3D G3DSA:1.10.10.10 2 102 1.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SUPERFAMILY SSF46894 10 101 2.04E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Pfam PF00486 Transcriptional regulatory protein, C terminal 34 99 1.3E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 SUPERFAMILY SSF48452 103 263 7.97E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Pfam PF00931 NB-ARC domain 303 550 1.7E-9 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS01975 d6ac98a2b0d530d6cd7e6cc108f1bc87 940 Gene3D G3DSA:1.25.40.10 818 936 3.0E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS09020 94fe56607bea2fc0540deb23ef0c74ca 402 Gene3D G3DSA:3.40.190.10 155 396 6.5E-37 T 28-03-2018 CNX65_RS09020 94fe56607bea2fc0540deb23ef0c74ca 402 SUPERFAMILY SSF53850 16 399 5.43E-70 T 28-03-2018 CNX65_RS09020 94fe56607bea2fc0540deb23ef0c74ca 402 Pfam PF13416 Bacterial extracellular solute-binding protein 47 343 1.1E-34 T 28-03-2018 CNX65_RS09020 94fe56607bea2fc0540deb23ef0c74ca 402 Gene3D G3DSA:3.40.190.10 26 154 2.6E-22 T 28-03-2018 CNX65_RS29150 17846d0e22051cc0e6406fdf29217f4d 164 Pfam PF09349 OHCU decarboxylase 24 158 2.4E-29 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CNX65_RS29150 17846d0e22051cc0e6406fdf29217f4d 164 SUPERFAMILY SSF158694 24 162 1.83E-34 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CNX65_RS29150 17846d0e22051cc0e6406fdf29217f4d 164 Gene3D G3DSA:1.10.3330.10 20 164 3.0E-37 T 28-03-2018 IPR018020 Oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase KEGG: 00230+4.1.1.97|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CNX65_RS17985 fd2404cec667b642095c707f1b338ce6 374 SUPERFAMILY SSF51445 30 232 9.83E-33 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS17985 fd2404cec667b642095c707f1b338ce6 374 Gene3D G3DSA:3.20.20.80 17 237 5.0E-40 T 28-03-2018 CNX65_RS17985 fd2404cec667b642095c707f1b338ce6 374 SMART SM00641 30 132 3.5E-10 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CNX65_RS17985 fd2404cec667b642095c707f1b338ce6 374 Pfam PF01183 Glycosyl hydrolases family 25 33 192 2.1E-19 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CNX65_RS03510 4a3ea0aa885c706e5e3458dc79cb7d0c 393 SUPERFAMILY SSF54593 27 380 1.48E-88 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS03510 4a3ea0aa885c706e5e3458dc79cb7d0c 393 TIGRFAM TIGR01263 4HPPD: 4-hydroxyphenylpyruvate dioxygenase 33 393 1.9E-128 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CNX65_RS03510 4a3ea0aa885c706e5e3458dc79cb7d0c 393 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 35 143 1.8E-7 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS03510 4a3ea0aa885c706e5e3458dc79cb7d0c 393 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 204 347 2.6E-14 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS03510 4a3ea0aa885c706e5e3458dc79cb7d0c 393 PIRSF PIRSF009283 22 393 4.3E-131 T 28-03-2018 IPR005956 4-hydroxyphenylpyruvate dioxygenase GO:0003868|GO:0009072|GO:0016701|GO:0055114 CNX65_RS03510 4a3ea0aa885c706e5e3458dc79cb7d0c 393 Gene3D G3DSA:3.10.180.10 16 188 6.9E-35 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS03510 4a3ea0aa885c706e5e3458dc79cb7d0c 393 Gene3D G3DSA:3.10.180.10 191 393 1.7E-66 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS26240 9a320c774f4470821b27f92a5a68e66c 212 SUPERFAMILY SSF52540 15 160 1.45E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26240 9a320c774f4470821b27f92a5a68e66c 212 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 39 157 1.3E-5 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CNX65_RS26240 9a320c774f4470821b27f92a5a68e66c 212 Gene3D G3DSA:3.40.50.300 12 203 1.6E-18 T 28-03-2018 CNX65_RS26240 9a320c774f4470821b27f92a5a68e66c 212 PRINTS PR00988 Uridine kinase signature 14 31 3.2E-8 T 28-03-2018 CNX65_RS26240 9a320c774f4470821b27f92a5a68e66c 212 PRINTS PR00988 Uridine kinase signature 144 154 3.2E-8 T 28-03-2018 CNX65_RS26240 9a320c774f4470821b27f92a5a68e66c 212 PRINTS PR00988 Uridine kinase signature 84 99 3.2E-8 T 28-03-2018 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 Pfam PF02065 Melibiase 257 592 1.1E-114 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 Gene3D G3DSA:2.60.40.1180 591 707 1.5E-11 T 28-03-2018 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 SUPERFAMILY SSF51445 291 621 4.56E-95 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 Gene3D G3DSA:2.70.98.60 2 276 3.6E-67 T 28-03-2018 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 Gene3D G3DSA:3.20.20.70 278 590 2.4E-48 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 23 244 1.7E-43 T 28-03-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 372 394 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 428 443 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 259 279 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 294 308 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 322 337 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 208 223 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 503 519 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PRINTS PR00743 Glycosyl hydrolase family 36 signature 478 494 2.6E-46 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS30435 450d2b71deb850e228b2c5ad4dce0ab6 707 PIRSF PIRSF005536 75 666 3.3E-171 T 28-03-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 CNX65_RS06855 c8e292cdc7ca1da3058106ffa2783e46 262 SUPERFAMILY SSF56300 2 41 2.44E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS06855 c8e292cdc7ca1da3058106ffa2783e46 262 SUPERFAMILY SSF56300 84 253 2.44E-32 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS06855 c8e292cdc7ca1da3058106ffa2783e46 262 Gene3D G3DSA:3.60.21.10 1 261 2.9E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS06855 c8e292cdc7ca1da3058106ffa2783e46 262 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 253 2.4E-6 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CNX65_RS10675 6499284384de29978dfc998b79c051ee 327 Gene3D G3DSA:3.90.79.10 161 316 1.1E-21 T 28-03-2018 CNX65_RS10675 6499284384de29978dfc998b79c051ee 327 Pfam PF00293 NUDIX domain 171 295 4.4E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS10675 6499284384de29978dfc998b79c051ee 327 Gene3D G3DSA:1.20.1440.20 19 160 3.5E-33 T 28-03-2018 CNX65_RS10675 6499284384de29978dfc998b79c051ee 327 SUPERFAMILY SSF55811 166 304 2.17E-20 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS10675 6499284384de29978dfc998b79c051ee 327 ProSitePatterns PS00893 Nudix box signature. 207 228 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS10675 6499284384de29978dfc998b79c051ee 327 SUPERFAMILY SSF140478 32 130 3.92E-5 T 28-03-2018 IPR023353 LemA-like domain CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 Gene3D G3DSA:3.20.20.240 523 1068 2.3E-189 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 704 1071 9.7E-92 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 Gene3D G3DSA:3.40.50.280 2 154 5.5E-25 T 28-03-2018 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 5 1072 16.577 T 28-03-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 SUPERFAMILY SSF52242 4 137 5.23E-40 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 Pfam PF01642 Methylmalonyl-CoA mutase 550 1066 3.6E-143 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 Pfam PF02310 B12 binding domain 8 102 6.9E-11 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 SUPERFAMILY SSF52540 151 411 1.16E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 Gene3D G3DSA:3.40.50.300 187 395 8.9E-30 T 28-03-2018 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 SUPERFAMILY SSF51703 493 1068 1.33E-149 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS11585 9605b8feccec06d2f555df498d1118c1 1072 Pfam PF03308 ArgK protein 159 391 2.1E-39 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF51735 4561 4741 2.44E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 417 531 1.7E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3773 3895 4.5E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2093 2212 9.6E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF53901 1727 2088 7.01E-106 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3560 3576 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1668 1683 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF53901 36 415 8.58E-100 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2248 2536 9.1E-127 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3931 4218 1.1E-125 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 564 852 1.0E-132 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00825 Beta-ketoacyl synthase 3413 3823 1.0E-218 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00825 Beta-ketoacyl synthase 1733 2143 2.1E-221 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00825 Beta-ketoacyl synthase 41 467 1.8E-214 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.30.70.250 694 732 1.0E-18 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF51735 1364 1594 5.44E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.50.1820 5134 5398 2.6E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.47.10 304 465 9.3E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.47.10 3662 3821 8.2E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.47.10 1982 2141 1.7E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.50.720 4751 4954 3.6E-47 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1731 1967 2.4E-85 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 39 289 6.0E-90 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3411 3647 5.5E-83 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.47.10 1733 1979 1.7E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.47.10 31 301 1.9E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF51735 2890 3031 1.14E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00550 Phosphopantetheine attachment site 5039 5104 3.5E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00550 Phosphopantetheine attachment site 3321 3387 3.0E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00550 Phosphopantetheine attachment site 1644 1709 7.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.366.10 733 856 4.7E-33 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.366.10 2423 2543 4.2E-32 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.366.10 4107 4222 6.7E-32 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM01294 3320 3387 1.0E-6 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM01294 1642 1709 1.0E-5 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM01294 5037 5104 3.5E-6 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 202 218 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.366.10 3927 4064 2.2E-47 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.366.10 560 693 5.1E-48 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.366.10 2244 2381 7.3E-50 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.30.70.250 2382 2422 1.4E-17 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.30.70.250 4065 4106 2.7E-17 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:1.10.1200.10 5029 5133 2.6E-20 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:1.10.1200.10 1634 1732 1.5E-21 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1880 1896 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.50.720 1363 1598 1.1E-42 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.50.720 3041 3276 5.2E-42 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF51735 4753 5006 3.04E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF47336 1635 1746 2.09E-26 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF52151 561 682 9.68E-77 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF52151 739 851 9.68E-77 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF52151 3928 4049 5.49E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF52151 4106 4206 5.49E-75 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF08990 Erythronolide synthase docking 7 32 1.9E-13 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF55048 2371 2429 2.88E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF52151 2245 2366 2.88E-77 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF52151 2423 2538 2.88E-77 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF47336 3315 3426 7.33E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF51735 1184 1340 2.32E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00698 Acyl transferase domain 3930 4236 4.2E-57 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00698 Acyl transferase domain 2247 2554 3.0E-59 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00698 Acyl transferase domain 563 870 1.0E-57 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF00975 Thioesterase domain 5187 5391 1.4E-24 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00826 4285 4448 2.7E-76 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00826 2603 2764 3.6E-79 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00826 919 1082 6.9E-81 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1364 1538 5.4E-46 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3042 3216 2.2E-50 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4755 4933 3.7E-53 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF14765 Polyketide synthase dehydratase 919 1188 5.4E-51 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF14765 Polyketide synthase dehydratase 4285 4557 1.0E-49 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF14765 Polyketide synthase dehydratase 2603 2871 9.3E-55 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5063 5078 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF55048 4054 4112 1.44E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1975 2090 6.1E-45 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 297 414 5.3E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3655 3770 1.3E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00823 Phosphopantetheine attachment site 5036 5108 9.1E-27 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00823 Phosphopantetheine attachment site 1641 1713 2.1E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00823 Phosphopantetheine attachment site 3319 3391 1.0E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF47336 5032 5119 3.01E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.40.47.10 3402 3652 2.0E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SMART SM00824 Thioesterase 5185 5395 2.6E-92 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF08659 KR domain 3042 3214 2.1E-53 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF08659 KR domain 1364 1535 3.9E-52 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Pfam PF08659 KR domain 4756 4931 7.6E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:1.10.1200.10 3285 3400 9.2E-20 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF53901 3407 3768 3.49E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF53474 5067 5104 2.12E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF53474 5160 5394 2.12E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF51735 3041 3283 2.78E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.10.129.10 2605 2727 8.1E-9 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.10.129.10 920 1046 2.5E-7 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 Gene3D G3DSA:3.10.129.10 4290 4409 4.0E-9 T 28-03-2018 CNX65_RS13590 506e0ba1b133349cdbebfa4c6bf39691 5398 SUPERFAMILY SSF55048 687 745 5.36E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 Gene3D G3DSA:3.40.50.2300 2 128 2.1E-33 T 28-03-2018 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 5.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 2.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 2.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 2.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 SMART SM00421 149 206 2.5E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 SMART SM00448 3 117 1.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 SUPERFAMILY SSF46894 137 209 1.84E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 SUPERFAMILY SSF52172 2 128 1.57E-29 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 Gene3D G3DSA:1.10.10.10 129 212 1.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30000 801f0b94d2fd523b62c270e10eae4cd2 218 Pfam PF00072 Response regulator receiver domain 5 118 8.6E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS25680 a6d664cbbd06ee276b54558069409c5a 257 Pfam PF01061 ABC-2 type transporter 27 224 4.8E-16 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS25680 a6d664cbbd06ee276b54558069409c5a 257 PIRSF PIRSF006648 5 256 6.3E-15 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS04420 9e9f80a1e4ad9e1c5e2545e20284537b 455 SUPERFAMILY SSF49899 262 448 5.81E-22 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS04420 9e9f80a1e4ad9e1c5e2545e20284537b 455 Gene3D G3DSA:2.60.40.10 141 247 2.0E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS04420 9e9f80a1e4ad9e1c5e2545e20284537b 455 SMART SM00560 321 443 1.9E-4 T 28-03-2018 IPR006558 LamG-like jellyroll fold CNX65_RS04420 9e9f80a1e4ad9e1c5e2545e20284537b 455 Gene3D G3DSA:2.60.120.200 253 453 5.4E-25 T 28-03-2018 CNX65_RS04420 9e9f80a1e4ad9e1c5e2545e20284537b 455 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 308 444 1.7E-18 T 28-03-2018 CNX65_RS09750 bb26fa7c92494fafaac7d038996b4a47 241 SUPERFAMILY SSF46689 27 89 9.98E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS09750 bb26fa7c92494fafaac7d038996b4a47 241 SUPERFAMILY SSF48498 100 238 2.78E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS09750 bb26fa7c92494fafaac7d038996b4a47 241 Gene3D G3DSA:1.10.357.10 92 241 3.2E-25 T 28-03-2018 CNX65_RS09750 bb26fa7c92494fafaac7d038996b4a47 241 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 78 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS09750 bb26fa7c92494fafaac7d038996b4a47 241 Gene3D G3DSA:1.10.10.60 2 86 4.5E-15 T 28-03-2018 CNX65_RS09750 bb26fa7c92494fafaac7d038996b4a47 241 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 93 237 2.4E-12 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 43 266 6.8E-91 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 Gene3D G3DSA:1.10.10.10 119 171 1.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 Pfam PF04545 Sigma-70, region 4 215 264 5.3E-17 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 Gene3D G3DSA:1.10.10.10 205 263 4.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 45 264 3.1E-38 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 Pfam PF04542 Sigma-70 region 2 49 118 3.3E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 SUPERFAMILY SSF88659 186 267 2.8E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 SUPERFAMILY SSF88946 29 118 3.4E-28 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 Pfam PF04539 Sigma-70 region 3 133 188 1.0E-12 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 SUPERFAMILY SSF88659 122 196 1.61E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 PRINTS PR00046 Major sigma-70 factor signature 236 251 9.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 PRINTS PR00046 Major sigma-70 factor signature 73 86 9.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 PRINTS PR00046 Major sigma-70 factor signature 251 262 9.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 PRINTS PR00046 Major sigma-70 factor signature 219 231 9.1E-10 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26705 aac76ba5ab83b13ace270fa5c242c476 268 Gene3D G3DSA:1.10.601.10 19 117 8.5E-20 T 28-03-2018 CNX65_RS28095 5b3e22cda33c47af055eca1391f95dda 226 SUPERFAMILY SSF88697 4 199 3.23E-38 T 28-03-2018 IPR015947 PUA-like domain CNX65_RS28095 5b3e22cda33c47af055eca1391f95dda 226 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 4 200 4.1E-19 T 28-03-2018 IPR003111 Lon, substrate-binding domain CNX65_RS28095 5b3e22cda33c47af055eca1391f95dda 226 Gene3D G3DSA:2.30.130.40 1 116 3.5E-28 T 28-03-2018 CNX65_RS28095 5b3e22cda33c47af055eca1391f95dda 226 SMART SM00464 4 201 7.9E-12 T 28-03-2018 IPR003111 Lon, substrate-binding domain CNX65_RS28095 5b3e22cda33c47af055eca1391f95dda 226 Gene3D G3DSA:1.10.4060.10 118 209 3.1E-8 T 28-03-2018 CNX65_RS30910 6dedfee09d32e678890e629e8c28c62e 210 SUPERFAMILY SSF82607 46 127 6.54E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS30910 6dedfee09d32e678890e629e8c28c62e 210 Pfam PF02575 YbaB/EbfC DNA-binding family 51 130 4.7E-10 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS30910 6dedfee09d32e678890e629e8c28c62e 210 Gene3D G3DSA:3.30.1310.10 38 145 7.3E-17 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 Gene3D G3DSA:3.40.50.2300 1 137 5.8E-30 T 28-03-2018 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 140 154 4.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 170 4.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 182 4.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 SUPERFAMILY SSF52172 1 129 5.27E-29 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 ProSitePatterns PS00622 LuxR-type HTH domain signature. 154 181 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 SUPERFAMILY SSF46894 132 200 3.13E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 SMART SM00421 137 194 1.5E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 139 194 1.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 Pfam PF00072 Response regulator receiver domain 4 115 2.7E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 Gene3D G3DSA:1.10.10.10 138 200 1.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08130 8f2d6854f83c433f68207a5974fce402 200 SMART SM00448 2 115 3.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS20605 5edf0513df4981ab63b7d662d9f9be6f 276 Pfam PF00378 Enoyl-CoA hydratase/isomerase 16 235 6.0E-47 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS20605 5edf0513df4981ab63b7d662d9f9be6f 276 SUPERFAMILY SSF52096 2 241 2.03E-63 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS20605 5edf0513df4981ab63b7d662d9f9be6f 276 Gene3D G3DSA:3.90.226.10 2 258 1.8E-59 T 28-03-2018 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 SUPERFAMILY SSF55874 223 398 1.44E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 Pfam PF00072 Response regulator receiver domain 418 529 5.3E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 12 129 2.3E-14 T 28-03-2018 IPR000014 PAS domain CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 Pfam PF00989 PAS fold 14 125 4.2E-12 T 28-03-2018 IPR013767 PAS fold GO:0006355 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 Gene3D G3DSA:3.40.50.2300 411 542 9.4E-25 T 28-03-2018 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 SUPERFAMILY SSF47384 148 230 8.24E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 Gene3D G3DSA:1.10.287.130 155 228 4.0E-6 T 28-03-2018 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 Gene3D G3DSA:3.30.450.20 11 154 1.7E-17 T 28-03-2018 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 SMART SM00387 273 396 8.5E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 SUPERFAMILY SSF52172 415 538 1.57E-26 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 SMART SM00448 416 529 3.0E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 SMART SM00091 12 78 3.6E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 393 3.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 374 3.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 343 353 3.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 PRINTS PR00344 Bacterial sensor protein C-terminal signature 325 339 3.1E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 Gene3D G3DSA:3.30.565.10 230 396 1.8E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 SUPERFAMILY SSF55785 12 125 1.71E-15 T 28-03-2018 IPR000014 PAS domain CNX65_RS12025 aaff36ba6ab7af1aef28664495926ccb 546 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 274 395 1.0E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10000 e85eb48f75b699a7d3c04ee44bea46cb 140 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 130 8.5E-11 T 28-03-2018 IPR028973 PhnB-like CNX65_RS10000 e85eb48f75b699a7d3c04ee44bea46cb 140 SUPERFAMILY SSF54593 1 132 4.95E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS10000 e85eb48f75b699a7d3c04ee44bea46cb 140 Gene3D G3DSA:3.10.180.10 1 139 4.5E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS03810 ff9bfe9fccdd6242ebabeaf1007782f3 324 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 238 270 1.8E-14 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS03810 ff9bfe9fccdd6242ebabeaf1007782f3 324 SUPERFAMILY SSF51161 78 302 1.52E-36 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS03810 ff9bfe9fccdd6242ebabeaf1007782f3 324 Hamap MF_02122 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase [dapD]. 7 321 43.813 T 28-03-2018 IPR026586 Type 2 tetrahydrodipicolinate N-succinyltransferase family GO:0008666 KEGG: 00300+2.3.1.117 CNX65_RS03810 ff9bfe9fccdd6242ebabeaf1007782f3 324 Gene3D G3DSA:2.160.10.10 157 292 1.3E-16 T 28-03-2018 CNX65_RS03810 ff9bfe9fccdd6242ebabeaf1007782f3 324 Gene3D G3DSA:3.30.60.70 117 156 9.4E-22 T 28-03-2018 CNX65_RS03810 ff9bfe9fccdd6242ebabeaf1007782f3 324 TIGRFAM TIGR03535 DapD_actino: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase 9 323 9.4E-153 T 28-03-2018 IPR019875 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, actinobacteria KEGG: 00300+2.3.1.117 CNX65_RS03810 ff9bfe9fccdd6242ebabeaf1007782f3 324 Pfam PF14789 Tetrahydrodipicolinate N-succinyltransferase middle 117 156 1.3E-20 T 28-03-2018 IPR032784 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase, middle domain KEGG: 00300+2.3.1.117 CNX65_RS23585 f2223d0daec65e8b512ad115c95c33d6 183 Gene3D G3DSA:1.10.10.10 99 183 1.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23585 f2223d0daec65e8b512ad115c95c33d6 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 25 182 5.6E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS23585 f2223d0daec65e8b512ad115c95c33d6 183 Pfam PF04542 Sigma-70 region 2 29 98 3.7E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS23585 f2223d0daec65e8b512ad115c95c33d6 183 Pfam PF08281 Sigma-70, region 4 127 177 6.1E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS23585 f2223d0daec65e8b512ad115c95c33d6 183 SUPERFAMILY SSF88659 120 182 2.62E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS23585 f2223d0daec65e8b512ad115c95c33d6 183 SUPERFAMILY SSF88946 6 115 3.66E-22 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS23585 f2223d0daec65e8b512ad115c95c33d6 183 Gene3D G3DSA:1.10.1740.10 5 98 3.7E-19 T 28-03-2018 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 Gene3D G3DSA:3.30.1360.40 80 151 2.3E-31 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 PRINTS PR01467 Bacterial arginine repressor signature 37 52 1.3E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 PRINTS PR01467 Bacterial arginine repressor signature 124 139 1.3E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 PRINTS PR01467 Bacterial arginine repressor signature 94 107 1.3E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 PRINTS PR01467 Bacterial arginine repressor signature 21 34 1.3E-27 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 Hamap MF_00173 Arginine repressor [argR]. 1 158 63.366 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 Gene3D G3DSA:1.10.10.10 3 67 9.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 Pfam PF02863 Arginine repressor, C-terminal domain 86 151 1.2E-25 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 SUPERFAMILY SSF46785 3 69 4.16E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 94 148 1.0E-17 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 9.4E-24 T 28-03-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 SUPERFAMILY SSF55252 86 150 1.23E-18 T 28-03-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 CNX65_RS27160 32df70c6f3a92f497a0ecbbf47213597 164 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 154 7.1E-48 T 28-03-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 CNX65_RS21505 6d9e5aa8d08230f8fc0989af469c4391 339 Gene3D G3DSA:1.10.3470.10 10 338 3.7E-64 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS21505 6d9e5aa8d08230f8fc0989af469c4391 339 Pfam PF01032 FecCD transport family 25 331 2.8E-74 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS21505 6d9e5aa8d08230f8fc0989af469c4391 339 SUPERFAMILY SSF81345 7 331 1.7E-67 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS14865 a2b3015d3e7d38b3335679eab01824dd 207 Gene3D G3DSA:1.10.10.10 105 207 1.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14865 a2b3015d3e7d38b3335679eab01824dd 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 3.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14865 a2b3015d3e7d38b3335679eab01824dd 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 3.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14865 a2b3015d3e7d38b3335679eab01824dd 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 3.4E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14865 a2b3015d3e7d38b3335679eab01824dd 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 1.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14865 a2b3015d3e7d38b3335679eab01824dd 207 SUPERFAMILY SSF46894 132 207 8.5E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS14865 a2b3015d3e7d38b3335679eab01824dd 207 SMART SM00421 144 201 1.4E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00385 P450 superfamily signature 274 285 8.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00385 P450 superfamily signature 341 350 8.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00385 P450 superfamily signature 350 361 8.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00385 P450 superfamily signature 239 256 8.2E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 137 153 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 320 335 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 274 285 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 341 350 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 292 319 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 192 214 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 350 361 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 PRINTS PR00359 B-class P450 signature 154 169 4.0E-42 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 Pfam PF00067 Cytochrome P450 174 370 1.8E-20 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 SUPERFAMILY SSF48264 14 401 1.19E-87 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 Gene3D G3DSA:1.10.630.10 2 401 3.2E-70 T 28-03-2018 CNX65_RS14610 68a309152858449e8ee63aa4bb8ba088 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 343 352 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS22065 cd68a183007460b964870408548710cd 438 Pfam PF12833 Helix-turn-helix domain 355 436 6.8E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22065 cd68a183007460b964870408548710cd 438 SUPERFAMILY SSF46689 385 436 2.03E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22065 cd68a183007460b964870408548710cd 438 SUPERFAMILY SSF46689 332 384 4.84E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22065 cd68a183007460b964870408548710cd 438 SMART SM00342 349 435 7.1E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22065 cd68a183007460b964870408548710cd 438 Gene3D G3DSA:1.10.10.60 329 385 1.1E-11 T 28-03-2018 CNX65_RS22065 cd68a183007460b964870408548710cd 438 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 386 431 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS22065 cd68a183007460b964870408548710cd 438 Gene3D G3DSA:1.10.10.60 386 438 2.5E-8 T 28-03-2018 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 SUPERFAMILY SSF46894 144 195 4.59E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 Gene3D G3DSA:1.10.10.10 129 210 9.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 1.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 1.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 1.4E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 Pfam PF00072 Response regulator receiver domain 2 105 2.7E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 SMART SM00448 1 117 2.5E-9 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 Pfam PF00196 Bacterial regulatory proteins, luxR family 145 192 4.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 SUPERFAMILY SSF52172 2 160 5.39E-20 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 SMART SM00421 144 207 7.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS04665 705cf40be4b77d2d2c0d873911a167fb 211 Gene3D G3DSA:3.40.50.2300 1 128 1.8E-22 T 28-03-2018 CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 SUPERFAMILY SSF46894 144 235 3.23E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 SUPERFAMILY SSF52172 10 175 5.69E-39 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 Gene3D G3DSA:3.40.50.2300 4 129 1.9E-35 T 28-03-2018 CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 Pfam PF00072 Response regulator receiver domain 14 122 1.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 Gene3D G3DSA:1.10.10.10 130 237 1.4E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 SMART SM00862 158 234 9.4E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 158 234 4.6E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS24705 e3ef09966475645f380916c6f4166219 238 SMART SM00448 12 122 1.7E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 SUPERFAMILY SSF51182 39 75 9.4E-5 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 Pfam PF12833 Helix-turn-helix domain 224 303 6.9E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 Pfam PF12852 Cupin 2 186 1.4E-47 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 Gene3D G3DSA:2.60.120.280 38 187 8.7E-7 T 28-03-2018 CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 Gene3D G3DSA:1.10.10.60 256 306 5.6E-10 T 28-03-2018 CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 SMART SM00342 218 301 1.3E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 SUPERFAMILY SSF46689 202 251 3.94E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 SUPERFAMILY SSF46689 254 303 2.73E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22185 9298fbc32cd1cf1225052fbf4b5e735f 316 Gene3D G3DSA:1.10.10.60 197 255 2.1E-10 T 28-03-2018 CNX65_RS14315 2f77db656f05cd0904a63ed99fb34c14 348 Pfam PF04616 Glycosyl hydrolases family 43 27 311 1.6E-45 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS14315 2f77db656f05cd0904a63ed99fb34c14 348 Gene3D G3DSA:2.115.10.20 24 319 2.8E-67 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS14315 2f77db656f05cd0904a63ed99fb34c14 348 SUPERFAMILY SSF75005 14 311 6.0E-68 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PIRSF PIRSF000126 1 258 1.3E-71 T 28-03-2018 CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 7.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 7.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 7.7E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 140 168 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 189 2.3E-5 T 28-03-2018 CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.5E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 3.5E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 3.5E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 3.5E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 3.5E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 SUPERFAMILY SSF51735 3 225 8.16E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 Pfam PF00106 short chain dehydrogenase 7 191 9.1E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11285 224f3d50efbe75abedeaa722b6b002d8 266 Gene3D G3DSA:3.40.50.720 1 259 4.4E-60 T 28-03-2018 CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 SMART SM00345 22 80 8.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 SMART SM00895 90 216 0.0025 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 SUPERFAMILY SSF46785 15 84 4.62E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 Pfam PF07729 FCD domain 90 213 5.3E-12 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 Pfam PF00392 Bacterial regulatory proteins, gntR family 23 80 9.1E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 Gene3D G3DSA:1.20.120.530 77 220 2.5E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 Gene3D G3DSA:1.10.10.10 6 76 5.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24215 5384bac0e4b1ef45e4ca27239ceaf5a4 243 SUPERFAMILY SSF48008 86 215 4.71E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS20415 91a81086079c282c181cab9def57c4f0 336 PIRSF PIRSF005739 3 289 1.0E-9 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CNX65_RS20415 91a81086079c282c181cab9def57c4f0 336 Pfam PF00891 O-methyltransferase 136 288 7.1E-18 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CNX65_RS20415 91a81086079c282c181cab9def57c4f0 336 SUPERFAMILY SSF46785 17 95 3.48E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20415 91a81086079c282c181cab9def57c4f0 336 Gene3D G3DSA:3.40.50.150 123 335 2.1E-24 T 28-03-2018 CNX65_RS20415 91a81086079c282c181cab9def57c4f0 336 Pfam PF16864 Dimerisation domain 17 93 3.1E-14 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CNX65_RS20415 91a81086079c282c181cab9def57c4f0 336 SUPERFAMILY SSF53335 105 321 5.02E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS20415 91a81086079c282c181cab9def57c4f0 336 Gene3D G3DSA:1.10.10.10 23 122 3.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19035 60202d1382283afcbf2649f1284e5a63 334 Pfam PF12840 Helix-turn-helix domain 258 314 3.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19035 60202d1382283afcbf2649f1284e5a63 334 SMART SM00418 255 329 4.4E-10 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19035 60202d1382283afcbf2649f1284e5a63 334 Gene3D G3DSA:1.10.10.10 235 329 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19035 60202d1382283afcbf2649f1284e5a63 334 SUPERFAMILY SSF46785 257 320 5.01E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19035 60202d1382283afcbf2649f1284e5a63 334 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 305 320 8.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19035 60202d1382283afcbf2649f1284e5a63 334 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 290 305 8.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19035 60202d1382283afcbf2649f1284e5a63 334 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 257 272 8.4E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS34430 3f842ee19ae560f8c453e94b8d3553aa 612 SUPERFAMILY SSF101898 174 473 1.52E-23 T 28-03-2018 CNX65_RS34430 3f842ee19ae560f8c453e94b8d3553aa 612 Gene3D G3DSA:2.120.10.30 173 341 2.8E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS34430 3f842ee19ae560f8c453e94b8d3553aa 612 SUPERFAMILY SSF52833 27 177 4.71E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS34430 3f842ee19ae560f8c453e94b8d3553aa 612 Gene3D G3DSA:2.120.10.30 356 477 3.2E-12 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS34430 3f842ee19ae560f8c453e94b8d3553aa 612 Gene3D G3DSA:3.40.30.10 9 166 3.0E-22 T 28-03-2018 CNX65_RS34430 3f842ee19ae560f8c453e94b8d3553aa 612 Pfam PF00578 AhpC/TSA family 17 136 1.6E-9 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS22005 2f42568d2ed1d273b1ea472900bc4440 186 SUPERFAMILY SSF109854 6 129 4.35E-20 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS22005 2f42568d2ed1d273b1ea472900bc4440 186 Gene3D G3DSA:1.20.120.450 2 130 1.2E-17 T 28-03-2018 CNX65_RS22005 2f42568d2ed1d273b1ea472900bc4440 186 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 7 124 4.6E-11 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS22005 2f42568d2ed1d273b1ea472900bc4440 186 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 7 180 2.8E-24 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS22005 2f42568d2ed1d273b1ea472900bc4440 186 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 8 180 1.7E-44 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 Pfam PF00196 Bacterial regulatory proteins, luxR family 56 99 1.9E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 SUPERFAMILY SSF52172 9 48 2.72E-5 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 Gene3D G3DSA:3.40.50.2300 7 45 7.2E-5 T 28-03-2018 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 59 75 2.4E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 75 87 2.4E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 ProSitePatterns PS00622 LuxR-type HTH domain signature. 59 86 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 SUPERFAMILY SSF46894 56 104 1.7E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 Gene3D G3DSA:1.10.1270.10 69 103 2.8E-7 T 28-03-2018 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 Gene3D G3DSA:1.10.10.60 46 68 4.6E-5 T 28-03-2018 CNX65_RS10855 f3353dddc7390c62a25d13932f106b6e 105 SMART SM00421 51 99 1.0E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08590 eb1368417fcc925a9c5cf5a5baa31d34 640 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 67 224 5.3E-31 T 28-03-2018 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 766 846 3.5E-26 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Gene3D G3DSA:1.10.8.60 766 860 4.5E-24 T 28-03-2018 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Pfam PF07724 AAA domain (Cdc48 subfamily) 598 759 6.4E-54 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Gene3D G3DSA:1.10.1780.10 5 152 1.1E-36 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 SUPERFAMILY SSF81923 7 157 3.83E-36 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 666 6.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 710 724 6.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 677 695 6.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 603 621 6.3E-42 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 95 146 3.1E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 67 4.1E-10 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Gene3D G3DSA:1.10.8.60 345 549 1.1E-45 T 28-03-2018 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 SMART SM00382 199 345 1.3E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 SMART SM00382 599 748 1.0E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 296 308 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 633 651 - T 28-03-2018 IPR028299 ClpA/B, conserved site 2 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 SUPERFAMILY SSF52540 158 547 4.77E-95 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 318 1.4E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Gene3D G3DSA:3.40.50.300 158 344 7.6E-24 T 28-03-2018 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 SMART SM01086 766 857 4.3E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 SUPERFAMILY SSF52540 548 850 2.44E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 Gene3D G3DSA:3.40.50.300 554 765 2.5E-49 T 28-03-2018 CNX65_RS34305 113f170b737823d4b500c962d2b9a274 860 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 7 852 0.0 T 28-03-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0016485 CNX65_RS27355 e37c86675e66361fefc8b698a4042501 296 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 23 131 1.3E-12 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS27355 e37c86675e66361fefc8b698a4042501 296 SUPERFAMILY SSF55961 5 150 4.02E-32 T 28-03-2018 CNX65_RS27355 e37c86675e66361fefc8b698a4042501 296 SUPERFAMILY SSF55961 165 291 7.41E-13 T 28-03-2018 CNX65_RS27355 e37c86675e66361fefc8b698a4042501 296 Gene3D G3DSA:3.30.530.20 156 296 2.6E-6 T 28-03-2018 IPR023393 START-like domain CNX65_RS27355 e37c86675e66361fefc8b698a4042501 296 Gene3D G3DSA:3.30.530.20 2 154 2.6E-25 T 28-03-2018 IPR023393 START-like domain CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 SUPERFAMILY SSF51445 49 371 1.16E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 SUPERFAMILY SSF51445 398 505 1.16E-130 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 Pfam PF00128 Alpha amylase, catalytic domain 73 429 2.0E-73 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 Gene3D G3DSA:2.60.40.1180 508 603 2.8E-22 T 28-03-2018 CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 Pfam PF16657 Maltogenic Amylase, C-terminal domain 508 590 1.5E-19 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 TIGRFAM TIGR02456 treS_nterm: trehalose synthase 50 593 7.7E-288 T 28-03-2018 IPR012810 Trehalose synthase/alpha-amylase, N-terminal GO:0003824|GO:0005975 KEGG: 00500+5.4.99.16|MetaCyc: PWY-2622 CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 SMART SM00642 58 460 9.2E-114 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 Gene3D G3DSA:3.20.20.80 55 507 9.1E-122 T 28-03-2018 CNX65_RS29890 6a92be84351a19290401f837d91d19dc 604 SUPERFAMILY SSF51011 513 593 9.6E-16 T 28-03-2018 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 SUPERFAMILY SSF47203 228 384 6.44E-38 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 Gene3D G3DSA:1.10.540.10 1 119 3.1E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 117 2.0E-22 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 SUPERFAMILY SSF56645 5 242 6.68E-56 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 Gene3D G3DSA:2.40.110.10 121 221 4.2E-25 T 28-03-2018 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 Gene3D G3DSA:1.20.140.10 222 386 1.3E-39 T 28-03-2018 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 9.8E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS08550 8e59668ad5fc76b7ba7b3f574c1cd238 386 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 200 2.5E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 212 226 1.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 353 1.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 359 372 1.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 PRINTS PR00344 Bacterial sensor protein C-terminal signature 319 329 1.5E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 SUPERFAMILY SSF158472 101 150 1.96E-8 T 28-03-2018 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 Pfam PF00672 HAMP domain 101 150 3.5E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 SUPERFAMILY SSF47384 137 219 7.46E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 Gene3D G3DSA:3.30.565.10 224 376 2.7E-35 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 SMART SM00388 154 221 5.7E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 264 373 1.1E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 SMART SM00304 100 153 7.6E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 Pfam PF00512 His Kinase A (phospho-acceptor) domain 154 220 9.9E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 SMART SM00387 264 375 1.9E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 Gene3D G3DSA:1.10.287.130 144 217 2.9E-16 T 28-03-2018 CNX65_RS07565 74a8044cbf9ac6d7d78be18f1ce0ae1e 376 SUPERFAMILY SSF55874 228 372 5.24E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 SMART SM00421 148 210 4.3E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 SUPERFAMILY SSF52172 2 167 1.45E-20 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 Pfam PF00072 Response regulator receiver domain 3 108 7.3E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 SMART SM00448 1 120 3.3E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 Gene3D G3DSA:3.40.50.2300 1 131 6.5E-22 T 28-03-2018 CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 Gene3D G3DSA:1.10.10.10 132 216 4.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.1E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13665 8b43839769eb972749f8e9eca96ecdb3 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 196 8.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 TIGRFAM TIGR00759 aceE: pyruvate dehydrogenase (acetyl-transferring), homodimeric type 24 909 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 SUPERFAMILY SSF52518 496 724 3.09E-88 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 SUPERFAMILY SSF52518 75 491 1.38E-130 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 155 323 4.0E-10 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 Gene3D G3DSA:3.40.50.970 494 729 5.6E-69 T 28-03-2018 CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 Gene3D G3DSA:3.40.50.970 74 493 8.6E-84 T 28-03-2018 CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 PIRSF PIRSF000156 15 913 0.0 T 28-03-2018 IPR004660 2-oxo-acid dehydrogenase E1 component homodimeric type GO:0016491|GO:0055114 KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 Gene3D G3DSA:3.40.50.920 731 913 5.3E-42 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS06585 04c83fc8aa3ec5612187e7bc44e996e9 919 SUPERFAMILY SSF52922 727 905 6.85E-55 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS30045 85b02c1756b9fc5b8208e1844806708e 234 Pfam PF12697 Alpha/beta hydrolase family 9 224 8.6E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS30045 85b02c1756b9fc5b8208e1844806708e 234 Gene3D G3DSA:3.40.50.1820 4 234 1.2E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30045 85b02c1756b9fc5b8208e1844806708e 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 79 92 3.7E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS30045 85b02c1756b9fc5b8208e1844806708e 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 176 190 3.7E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS30045 85b02c1756b9fc5b8208e1844806708e 234 PRINTS PR00111 Alpha/beta hydrolase fold signature 65 78 3.7E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS30045 85b02c1756b9fc5b8208e1844806708e 234 SUPERFAMILY SSF53474 8 228 3.01E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 366 3.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 387 405 3.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 380 3.1E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 Gene3D G3DSA:3.30.565.10 265 427 6.4E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 SMART SM00388 211 276 3.7E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 Pfam PF00512 His Kinase A (phospho-acceptor) domain 212 276 4.4E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 SUPERFAMILY SSF47384 194 277 2.55E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 SMART SM00387 317 427 5.3E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 Gene3D G3DSA:1.10.287.130 201 264 8.8E-11 T 28-03-2018 CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 SUPERFAMILY SSF55874 267 425 1.11E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03725 d7b30db4cf2ac9145f1808c1eb948788 427 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 323 424 1.9E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 Gene3D G3DSA:3.40.50.920 490 621 2.0E-29 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 Gene3D G3DSA:3.40.50.970 313 485 1.0E-40 T 28-03-2018 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 Pfam PF02780 Transketolase, C-terminal domain 494 611 4.1E-26 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 SUPERFAMILY SSF52518 3 348 8.63E-68 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 SUPERFAMILY SSF52518 295 478 1.28E-51 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 SMART SM00861 317 481 1.3E-53 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 ProSitePatterns PS00802 Transketolase signature 2. 423 439 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 4 281 8.9E-109 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 ProSitePatterns PS00801 Transketolase signature 1. 29 48 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 6 619 5.6E-183 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 SUPERFAMILY SSF52922 496 619 1.96E-24 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 3 620 41.006 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 Gene3D G3DSA:3.40.50.970 1 312 2.9E-78 T 28-03-2018 CNX65_RS07550 c2411de75d86e3a811ff44a5cadb9462 633 Pfam PF02779 Transketolase, pyrimidine binding domain 316 479 8.1E-38 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS19585 734f6191caae9c07735cc9ff2fe12651 426 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 229 266 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS19585 734f6191caae9c07735cc9ff2fe12651 426 Gene3D G3DSA:3.90.1150.10 301 424 2.0E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS19585 734f6191caae9c07735cc9ff2fe12651 426 Pfam PF00202 Aminotransferase class-III 39 411 4.2E-81 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS19585 734f6191caae9c07735cc9ff2fe12651 426 SUPERFAMILY SSF53383 35 411 2.36E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS19585 734f6191caae9c07735cc9ff2fe12651 426 Gene3D G3DSA:3.40.640.10 59 300 2.4E-73 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS15670 0d85aba6297be70323070821b18c5799 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 3.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS15670 0d85aba6297be70323070821b18c5799 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 73 3.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS15670 0d85aba6297be70323070821b18c5799 136 PRINTS PR00598 Bacterial regulatory protein MarR family signature 108 128 3.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS15670 0d85aba6297be70323070821b18c5799 136 Gene3D G3DSA:1.10.10.10 2 133 5.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15670 0d85aba6297be70323070821b18c5799 136 SUPERFAMILY SSF46785 13 130 2.11E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15670 0d85aba6297be70323070821b18c5799 136 Pfam PF12802 MarR family 21 80 4.5E-11 T 28-03-2018 CNX65_RS15670 0d85aba6297be70323070821b18c5799 136 SMART SM00347 15 118 1.5E-15 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF47336 2926 2996 1.44E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00455 Putative AMP-binding domain signature. 548 559 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SMART SM00823 Phosphopantetheine attachment site 903 970 3.6E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SMART SM00823 Phosphopantetheine attachment site 1894 1961 3.7E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SMART SM00823 Phosphopantetheine attachment site 3976 4044 5.3E-12 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SMART SM00823 Phosphopantetheine attachment site 2933 3002 4.6E-10 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.300.30 1784 1900 8.0E-30 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.300.30 3862 3981 4.7E-34 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.300.30 793 908 1.5E-31 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.300.30 2824 2936 3.9E-34 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3999 4014 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 4221 4439 4.56E-36 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 1983 2179 2.89E-35 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF56801 2398 2946 4.58E-137 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2957 2972 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 2431 2576 5.5E-42 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 418 549 5.1E-37 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 3200 3464 2.78E-60 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:2.30.38.10 710 788 1.3E-23 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:2.30.38.10 3776 3857 1.6E-24 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 3023 3193 4.22E-48 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00550 Phosphopantetheine attachment site 2935 2996 1.9E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00550 Phosphopantetheine attachment site 1896 1956 2.1E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00550 Phosphopantetheine attachment site 3978 4039 1.2E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00550 Phosphopantetheine attachment site 906 964 1.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 3469 3623 1.3E-42 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 1393 1535 7.6E-44 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 2164 2402 1.89E-50 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 4058 4233 6.0E-27 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:2.30.38.10 1693 1781 4.7E-20 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:2.30.38.10 2732 2821 6.7E-22 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00501 AMP-binding enzyme 2439 2829 3.0E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00501 AMP-binding enzyme 3477 3867 4.1E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00501 AMP-binding enzyme 426 798 1.3E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00501 AMP-binding enzyme 1403 1789 1.1E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:1.10.1200.10 1901 1957 1.3E-21 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF47336 899 964 1.96E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF13193 AMP-binding enzyme C-terminal domain 1797 1864 1.3E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF13193 AMP-binding enzyme C-terminal domain 3875 3951 9.4E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF13193 AMP-binding enzyme C-terminal domain 806 878 9.6E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF13193 AMP-binding enzyme C-terminal domain 2837 2908 2.7E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 3624 3769 7.0E-28 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 2577 2731 2.6E-29 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 1536 1692 2.2E-44 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:1.10.1200.10 3982 4049 1.8E-20 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:1.10.1200.10 909 979 5.7E-17 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2459 2853 2.8E-110 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1422 1813 2.2E-127 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3498 3891 5.2E-123 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 446 822 2.5E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 6 168 2.22E-25 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00012 Phosphopantetheine attachment site. 926 941 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF56801 388 916 1.96E-142 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.559.10 4050 4236 3.2E-24 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.559.10 3005 3215 3.0E-43 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3617 3628 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 1147 1371 5.45E-47 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF47336 3971 4040 1.7E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00668 Condensation domain 3019 3456 3.6E-97 T 28-03-2018 IPR001242 Condensation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00668 Condensation domain 993 1381 5.3E-47 T 28-03-2018 IPR001242 Condensation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00668 Condensation domain 3 407 7.4E-37 T 28-03-2018 IPR001242 Condensation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00668 Condensation domain 1985 2418 1.1E-60 T 28-03-2018 IPR001242 Condensation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Pfam PF00668 Condensation domain 4077 4354 1.8E-36 T 28-03-2018 IPR001242 Condensation domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1918 1933 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF56801 3436 3989 5.49E-147 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:1.10.1200.10 2937 3004 3.2E-22 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 993 1161 2.33E-24 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF47336 1888 1956 1.22E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF56801 1362 1907 2.22E-148 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 SUPERFAMILY SSF52777 172 386 1.78E-30 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1530 1541 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2571 2582 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.40.50.980 550 709 1.6E-36 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.559.10 1971 2172 3.4E-36 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.559.10 1 181 1.5E-17 T 28-03-2018 CNX65_RS24930 73cea9632972af17359b737a2034c176 4444 Gene3D G3DSA:3.30.559.10 981 1135 9.5E-25 T 28-03-2018 CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 Gene3D G3DSA:3.40.50.970 384 594 4.7E-49 T 28-03-2018 CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 SUPERFAMILY SSF52467 217 390 7.12E-62 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 224 359 9.8E-48 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 459 478 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 Gene3D G3DSA:3.40.50.970 28 223 1.4E-62 T 28-03-2018 CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 Gene3D G3DSA:3.40.50.1220 224 383 5.9E-56 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 422 575 1.7E-50 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 SUPERFAMILY SSF52518 401 608 8.22E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 35 200 1.0E-55 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 SUPERFAMILY SSF52518 31 215 1.21E-62 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS29615 0f3e29fcc676d5981bf7266fdd2d472c 611 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 35 598 3.4E-232 T 28-03-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CNX65_RS17345 6a44cb908fe019f2457ba670f24b2b30 143 Pfam PF01957 NfeD-like C-terminal, partner-binding 8 140 5.4E-19 T 28-03-2018 IPR002810 NfeD-like, C-terminal domain CNX65_RS17345 6a44cb908fe019f2457ba670f24b2b30 143 Gene3D G3DSA:2.40.50.140 72 141 3.6E-20 T 28-03-2018 CNX65_RS17345 6a44cb908fe019f2457ba670f24b2b30 143 SUPERFAMILY SSF141322 76 140 1.01E-7 T 28-03-2018 CNX65_RS19165 11f9b91626221d7f7245ba330c3ff05a 376 Gene3D G3DSA:3.40.640.10 25 243 1.7E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS19165 11f9b91626221d7f7245ba330c3ff05a 376 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 33 368 1.2E-81 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS19165 11f9b91626221d7f7245ba330c3ff05a 376 PIRSF PIRSF000390 14 375 7.0E-74 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS19165 11f9b91626221d7f7245ba330c3ff05a 376 Gene3D G3DSA:3.90.1150.10 244 376 2.2E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS19165 11f9b91626221d7f7245ba330c3ff05a 376 SUPERFAMILY SSF53383 17 371 1.22E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 Gene3D G3DSA:1.20.58.410 2 114 1.3E-28 T 28-03-2018 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 362 37.885 T 28-03-2018 IPR020853 Peptide chain release factor 2, bacterial GO:0005737|GO:0006415|GO:0016149 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 Gene3D G3DSA:3.30.160.20 223 322 1.3E-33 T 28-03-2018 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 SUPERFAMILY SSF75620 28 364 1.03E-121 T 28-03-2018 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 4 361 3.1E-155 T 28-03-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 SMART SM00937 83 193 1.8E-45 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 243 259 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 Pfam PF00472 RF-1 domain 228 334 2.1E-38 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CNX65_RS04645 1cb2a7f2df65dcc1f158d047b9cfc841 367 Pfam PF03462 PCRF domain 29 218 1.5E-55 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 Gene3D G3DSA:3.40.50.300 225 392 3.3E-23 T 28-03-2018 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 ProSitePatterns PS01008 DnaA protein signature. 522 541 - T 28-03-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 Gene3D G3DSA:1.10.8.60 394 465 2.1E-25 T 28-03-2018 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 SMART SM00760 472 541 6.9E-33 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 Gene3D G3DSA:1.10.1750.10 469 565 3.2E-33 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 475 541 9.8E-27 T 28-03-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 293 307 3.3E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 261 281 3.3E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 359 386 3.3E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 325 339 3.3E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 522 541 3.3E-51 T 28-03-2018 IPR020591 Chromosomal replication control, initiator DnaA-like CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 SUPERFAMILY SSF48295 459 564 3.92E-33 T 28-03-2018 IPR010921 Trp repressor/replication initiator GO:0043565 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 SUPERFAMILY SSF52540 227 439 1.7E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 SMART SM00382 260 388 3.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 Pfam PF00308 Bacterial dnaA protein 228 445 1.4E-101 T 28-03-2018 IPR013317 Chromosomal replication initiator protein DnaA CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 9 563 32.543 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CNX65_RS00005 c03d455b8d8c2de3142b70f0b9d51b62 577 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 24 562 2.0E-150 T 28-03-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 CNX65_RS10700 2d953a3425d463e46a300ff85c45af75 280 Gene3D G3DSA:3.60.110.10 4 276 7.2E-72 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS10700 2d953a3425d463e46a300ff85c45af75 280 SUPERFAMILY SSF56317 3 277 8.11E-75 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS10700 2d953a3425d463e46a300ff85c45af75 280 Pfam PF00795 Carbon-nitrogen hydrolase 6 260 1.4E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS06875 0575c1f30378a15d93a5f42f1b23a1b3 325 SUPERFAMILY SSF53067 3 312 6.24E-62 T 28-03-2018 CNX65_RS06875 0575c1f30378a15d93a5f42f1b23a1b3 325 Gene3D G3DSA:3.30.420.40 115 319 7.0E-57 T 28-03-2018 CNX65_RS06875 0575c1f30378a15d93a5f42f1b23a1b3 325 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 4 313 4.3E-78 T 28-03-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 CNX65_RS06875 0575c1f30378a15d93a5f42f1b23a1b3 325 ProSitePatterns PS01125 ROK family signature. 129 156 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS06875 0575c1f30378a15d93a5f42f1b23a1b3 325 Pfam PF00480 ROK family 3 311 1.5E-78 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS06875 0575c1f30378a15d93a5f42f1b23a1b3 325 Gene3D G3DSA:3.30.420.40 1 114 8.7E-31 T 28-03-2018 CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 SUPERFAMILY SSF51556 53 290 3.4E-75 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 SUPERFAMILY SSF51556 337 463 3.4E-75 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 Gene3D G3DSA:2.30.40.10 1 66 1.9E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 Pfam PF07969 Amidohydrolase family 41 508 8.9E-50 T 28-03-2018 IPR013108 Amidohydrolase 3 CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 Gene3D G3DSA:2.30.40.10 443 512 1.5E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 SUPERFAMILY SSF51338 463 517 9.04E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 SUPERFAMILY SSF51338 2 52 9.04E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS27300 dc2a576ae16eade33f83b7777bf4c980 529 Gene3D G3DSA:3.20.20.140 67 442 2.1E-84 T 28-03-2018 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 Gene3D G3DSA:3.90.1170.30 334 426 1.3E-25 T 28-03-2018 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 Gene3D G3DSA:1.20.970.10 4 73 2.7E-20 T 28-03-2018 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 SUPERFAMILY SSF54680 327 418 2.35E-23 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 SMART SM00941 340 414 9.7E-32 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 10 413 6.2E-159 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 413 2.3E-20 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 SUPERFAMILY SSF52418 76 322 7.06E-80 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 Pfam PF00591 Glycosyl transferase family, a/b domain 83 294 1.7E-28 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 PIRSF PIRSF000478 6 422 5.6E-148 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 11 72 6.0E-16 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 116 131 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 Gene3D G3DSA:3.40.1030.10 74 333 3.3E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS23540 f9cc305f8509fb771eba1bc40aaa4cc4 433 SUPERFAMILY SSF47648 7 75 6.54E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 256 364 3.2E-31 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 SUPERFAMILY SSF53738 4 179 7.46E-48 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Gene3D G3DSA:3.40.120.10 1 142 1.8E-45 T 28-03-2018 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 SUPERFAMILY SSF55957 356 442 1.44E-21 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 134 3.2E-41 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 372 438 4.1E-12 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 157 252 4.2E-21 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 441 5.6E-175 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Gene3D G3DSA:3.40.120.10 155 268 2.0E-33 T 28-03-2018 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 443 43.957 T 28-03-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 SUPERFAMILY SSF53738 156 254 1.53E-28 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 SUPERFAMILY SSF53738 256 362 3.3E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Gene3D G3DSA:3.30.310.50 373 443 7.4E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 Gene3D G3DSA:3.40.120.10 269 372 2.6E-30 T 28-03-2018 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 95 109 2.9E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 172 191 2.9E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 2.9E-13 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS32210 2e4c2d06ae6d0ff495caecd46656e130 444 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 96 105 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 Pfam PF04480 Protein of unknown function (DUF559) 1396 1470 7.2E-6 T 28-03-2018 IPR007569 Domain of unknown function DUF559 CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 Gene3D G3DSA:3.40.50.300 1152 1343 5.4E-16 T 28-03-2018 CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 SUPERFAMILY SSF52980 1370 1474 5.15E-14 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 Gene3D G3DSA:3.40.50.300 361 1123 1.0E-30 T 28-03-2018 CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 SUPERFAMILY SSF52540 378 412 1.13E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 SUPERFAMILY SSF52540 549 632 1.13E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 Pfam PF13086 AAA domain 363 461 2.3E-10 T 28-03-2018 CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 SUPERFAMILY SSF52540 1043 1325 1.09E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 SUPERFAMILY SSF52540 361 492 1.09E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 Pfam PF13087 AAA domain 1134 1325 4.0E-12 T 28-03-2018 CNX65_RS08155 834d39a8afff97388a6cc6fca325d226 1724 Gene3D G3DSA:3.40.960.10 1375 1479 3.8E-26 T 28-03-2018 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 SMART SM00841 129 184 4.6E-32 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 Gene3D G3DSA:2.40.50.140 129 184 2.0E-26 T 28-03-2018 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 28-03-2018 IPR013852 Translation elongation factor P/YeiP, conserved site CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 Gene3D G3DSA:2.40.50.140 65 126 2.2E-21 T 28-03-2018 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 1.1E-25 T 28-03-2018 IPR013185 Translation elongation factor, KOW-like CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 Hamap MF_00141 Elongation factor P [efp]. 1 185 48.699 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 SMART SM01185 67 121 3.7E-25 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 SUPERFAMILY SSF50104 2 63 1.5E-19 T 28-03-2018 IPR008991 Translation protein SH3-like domain CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 SUPERFAMILY SSF50249 65 127 6.0E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 SUPERFAMILY SSF50249 129 185 1.88E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 Pfam PF09285 Elongation factor P, C-terminal 129 184 8.2E-25 T 28-03-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 TIGRFAM TIGR00038 efp: translation elongation factor P 3 185 1.7E-75 T 28-03-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 120 7.7E-20 T 28-03-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 PIRSF PIRSF005901 1 186 1.4E-65 T 28-03-2018 IPR020599 Translation elongation factor P/YeiP CNX65_RS26125 852d290f3bdfff2e470388c2322105c8 187 Gene3D G3DSA:2.30.30.30 2 61 4.8E-25 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 SMART SM00758 772 920 4.0E-14 T 28-03-2018 IPR011658 PA14 domain CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 Gene3D G3DSA:3.90.182.10 771 1190 1.2E-32 T 28-03-2018 CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 SUPERFAMILY SSF56988 1295 1388 1.02E-11 T 28-03-2018 CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 Gene3D G3DSA:2.60.40.10 614 712 2.9E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 SUPERFAMILY SSF56988 774 942 1.06E-31 T 28-03-2018 CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 SUPERFAMILY SSF49899 1385 1508 1.31E-10 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 Pfam PF07691 PA14 domain 1295 1380 1.0E-5 T 28-03-2018 IPR011658 PA14 domain CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 Pfam PF07691 PA14 domain 773 927 2.7E-21 T 28-03-2018 IPR011658 PA14 domain CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 48 291 3.0E-7 T 28-03-2018 CNX65_RS24565 dd339d6a7736eba8480fe9560975d673 1510 Gene3D G3DSA:3.90.182.10 1280 1479 1.9E-17 T 28-03-2018 CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 Gene3D G3DSA:3.90.650.10 158 320 3.5E-39 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 Pfam PF00586 AIR synthase related protein, N-terminal domain 40 150 4.5E-20 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 SUPERFAMILY SSF56042 155 311 1.79E-29 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 Gene3D G3DSA:3.30.1330.10 10 152 7.9E-34 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 PIRSF PIRSF005303 10 320 7.3E-86 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 SUPERFAMILY SSF55326 13 149 1.79E-33 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 15 317 28.58 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CNX65_RS29405 5e3c7f28ce0648bdee4a1126494e0a21 321 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 16 319 4.8E-81 T 28-03-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 CNX65_RS27090 892af15246f12433e20b78876c456ac8 300 Hamap MF_00361 NAD kinase [nadK]. 4 289 29.994 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CNX65_RS27090 892af15246f12433e20b78876c456ac8 300 Pfam PF01513 ATP-NAD kinase 54 273 5.6E-61 T 28-03-2018 IPR002504 NAD kinase GO:0003951|GO:0006741|GO:0008152 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CNX65_RS27090 892af15246f12433e20b78876c456ac8 300 Gene3D G3DSA:2.60.200.30 144 264 1.5E-37 T 28-03-2018 IPR017437 ATP-NAD kinase, PpnK-type, all-beta GO:0003951|GO:0008152|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 CNX65_RS27090 892af15246f12433e20b78876c456ac8 300 SUPERFAMILY SSF111331 5 295 1.31E-75 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CNX65_RS27090 892af15246f12433e20b78876c456ac8 300 Gene3D G3DSA:3.40.50.10330 1 143 3.2E-32 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 Gene3D G3DSA:3.10.310.10 125 254 1.2E-34 T 28-03-2018 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 Pfam PF01678 Diaminopimelate epimerase 141 259 6.6E-15 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 Pfam PF01678 Diaminopimelate epimerase 5 123 1.1E-37 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 4 265 4.1E-63 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 Gene3D G3DSA:3.10.310.10 1 124 8.2E-50 T 28-03-2018 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 SUPERFAMILY SSF54506 3 125 3.92E-36 T 28-03-2018 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 267 28.382 T 28-03-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 64 78 - T 28-03-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 CNX65_RS07130 e610e3c85602d639d783e949edd3e35e 273 SUPERFAMILY SSF54506 131 265 1.13E-24 T 28-03-2018 CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 SMART SM00347 39 140 2.6E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 100 116 3.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 130 150 3.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 81 96 3.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 80 3.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 SUPERFAMILY SSF46785 9 153 6.63E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 Pfam PF01047 MarR family 53 104 2.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS05365 dc4285ee563faf6ffdba85199941e65a 164 Gene3D G3DSA:1.10.10.10 18 160 4.3E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Gene3D G3DSA:3.30.450.20 195 338 1.9E-23 T 28-03-2018 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Pfam PF08448 PAS fold 352 461 8.0E-10 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 SUPERFAMILY SSF55785 336 460 1.03E-9 T 28-03-2018 IPR000014 PAS domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Gene3D G3DSA:3.30.565.10 589 756 4.2E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 197 326 1.0E-13 T 28-03-2018 IPR000014 PAS domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Pfam PF13426 PAS domain 211 317 7.2E-9 T 28-03-2018 IPR000014 PAS domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 PRINTS PR00344 Bacterial sensor protein C-terminal signature 674 688 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 PRINTS PR00344 Bacterial sensor protein C-terminal signature 705 723 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 PRINTS PR00344 Bacterial sensor protein C-terminal signature 692 702 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 PRINTS PR00344 Bacterial sensor protein C-terminal signature 730 743 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Gene3D G3DSA:1.10.287.130 471 584 5.8E-9 T 28-03-2018 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 SUPERFAMILY SSF55874 591 744 5.63E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Gene3D G3DSA:3.30.450.20 339 470 3.0E-13 T 28-03-2018 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 SMART SM00387 628 746 5.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 SMART SM00091 345 412 190.0 T 28-03-2018 IPR000014 PAS domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 SMART SM00091 200 266 1.5E-5 T 28-03-2018 IPR000014 PAS domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Pfam PF00512 His Kinase A (phospho-acceptor) domain 477 587 3.0E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 SUPERFAMILY SSF47384 470 512 9.02E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 630 745 2.2E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12050 08242ac819b36c74b408090607632a6b 759 SUPERFAMILY SSF55785 211 326 1.24E-17 T 28-03-2018 IPR000014 PAS domain CNX65_RS21660 aea37dcb252f30117199197f6a962ff6 127 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 43 115 5.0E-7 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS21660 aea37dcb252f30117199197f6a962ff6 127 SUPERFAMILY SSF55399 35 127 2.48E-15 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS21660 aea37dcb252f30117199197f6a962ff6 127 Pfam PF00720 Subtilisin inhibitor-like 31 111 3.2E-10 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS21660 aea37dcb252f30117199197f6a962ff6 127 Gene3D G3DSA:3.30.350.10 26 127 1.1E-19 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS26695 6fe4cef7c21de6ab14025fae1b544584 265 SUPERFAMILY SSF55874 34 130 1.07E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26695 6fe4cef7c21de6ab14025fae1b544584 265 Pfam PF13581 Histidine kinase-like ATPase domain 14 129 2.7E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26695 6fe4cef7c21de6ab14025fae1b544584 265 Gene3D G3DSA:3.30.565.10 5 237 7.9E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30145 c8bc5c1790756914ca472705ad60ae61 172 SUPERFAMILY SSF55729 14 172 1.72E-28 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS30145 c8bc5c1790756914ca472705ad60ae61 172 Gene3D G3DSA:3.40.630.30 4 172 1.5E-34 T 28-03-2018 CNX65_RS30145 c8bc5c1790756914ca472705ad60ae61 172 Pfam PF00583 Acetyltransferase (GNAT) family 59 145 9.3E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 Gene3D G3DSA:3.90.230.10 1 261 9.7E-67 T 28-03-2018 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 35.11 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 6.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 6.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 6.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 6.5E-22 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 254 8.0E-74 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 SUPERFAMILY SSF55920 1 253 8.11E-72 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS17440 f20eb55f122d2e868ffa367474365850 264 Pfam PF00557 Metallopeptidase family M24 12 246 9.3E-43 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 Gene3D G3DSA:3.40.50.720 46 254 1.6E-56 T 28-03-2018 CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 Gene3D G3DSA:3.40.50.720 2 45 1.4E-7 T 28-03-2018 CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 145 173 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 SUPERFAMILY SSF51735 6 253 1.07E-69 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 158 177 2.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 138 146 2.5E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 252 1.8E-56 T 28-03-2018 CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 148 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 177 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13225 d0c3160fd638297dd9c8a4e1db9412f6 254 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 2.4E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 SMART SM00895 84 207 6.4E-24 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 Pfam PF07729 FCD domain 84 206 1.1E-22 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 SMART SM00345 17 74 1.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 Gene3D G3DSA:1.20.120.530 77 216 6.4E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 Gene3D G3DSA:1.10.10.10 6 76 2.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 SUPERFAMILY SSF46785 13 100 3.75E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 SUPERFAMILY SSF48008 79 214 2.62E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 35 49 1.2E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 65 1.2E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS14355 c3a7d144869560835e0fa598d8f9a03b 217 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 71 3.8E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 SUPERFAMILY SSF51905 355 407 1.42E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 SUPERFAMILY SSF51905 5 262 1.42E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 Pfam PF00890 FAD binding domain 11 391 2.2E-83 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 Gene3D G3DSA:3.50.50.60 310 407 1.2E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 Pfam PF02910 Fumarate reductase flavoprotein C-term 432 522 7.1E-9 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 10 504 8.8E-152 T 28-03-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 354 376 3.3E-10 T 28-03-2018 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 3.3E-10 T 28-03-2018 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 Gene3D G3DSA:1.20.58.100 418 523 1.0E-18 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.2E-7 T 28-03-2018 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 369 376 1.2E-7 T 28-03-2018 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 SUPERFAMILY SSF46977 429 525 3.66E-20 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 Gene3D G3DSA:3.50.50.60 1 308 3.5E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28080 f0e6ca519e32be6c89f8616dacb13d0e 538 SUPERFAMILY SSF56425 234 351 4.93E-31 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS03215 645ad06c973a5d53ca0e4e05118f1fa2 176 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 43 79 9.3E-15 T 28-03-2018 IPR019933 DivIVA domain CNX65_RS03215 645ad06c973a5d53ca0e4e05118f1fa2 176 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 1 37 2.7E-10 T 28-03-2018 IPR019933 DivIVA domain CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 SUPERFAMILY SSF46785 24 99 1.22E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 SUPERFAMILY SSF64288 77 252 6.28E-46 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 SMART SM00345 32 89 2.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 Gene3D G3DSA:1.10.10.10 32 92 4.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 Pfam PF00392 Bacterial regulatory proteins, gntR family 43 89 3.9E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 Pfam PF07702 UTRA domain 109 248 8.5E-35 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 SMART SM00866 109 249 3.0E-34 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 49 63 3.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 63 79 3.0E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS07295 6cd85bd7a60e2e8047cf93090964258c 257 Gene3D G3DSA:3.40.1410.10 93 257 7.7E-41 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS13970 5b29f9a2987bdc28fb3e0ad48fa9d9bd 403 SUPERFAMILY SSF51338 361 402 8.27E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS13970 5b29f9a2987bdc28fb3e0ad48fa9d9bd 403 SUPERFAMILY SSF51338 2 56 8.27E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS13970 5b29f9a2987bdc28fb3e0ad48fa9d9bd 403 Gene3D G3DSA:2.30.40.10 2 64 1.1E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS13970 5b29f9a2987bdc28fb3e0ad48fa9d9bd 403 SUPERFAMILY SSF51556 56 357 8.6E-79 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS13970 5b29f9a2987bdc28fb3e0ad48fa9d9bd 403 Gene3D G3DSA:3.20.20.140 65 355 1.3E-38 T 28-03-2018 CNX65_RS13970 5b29f9a2987bdc28fb3e0ad48fa9d9bd 403 Pfam PF01979 Amidohydrolase family 52 400 2.1E-39 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS08280 8c5e47b9cf1d33a6612befdf01b54e60 191 Pfam PF00293 NUDIX domain 52 145 2.0E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS08280 8c5e47b9cf1d33a6612befdf01b54e60 191 Gene3D G3DSA:3.90.79.10 11 189 6.2E-25 T 28-03-2018 CNX65_RS08280 8c5e47b9cf1d33a6612befdf01b54e60 191 SUPERFAMILY SSF55811 15 182 2.98E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS16775 b23ac0b8667314c25d109373e262ed7e 262 Gene3D G3DSA:3.40.50.1820 4 262 9.5E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16775 b23ac0b8667314c25d109373e262ed7e 262 Pfam PF12697 Alpha/beta hydrolase family 26 252 3.2E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS16775 b23ac0b8667314c25d109373e262ed7e 262 SUPERFAMILY SSF53474 6 260 7.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22145 c5a82bfdcd3ccedfffd26195974b5e21 303 SUPERFAMILY SSF51735 106 271 3.98E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22145 c5a82bfdcd3ccedfffd26195974b5e21 303 SUPERFAMILY SSF50129 2 145 2.52E-22 T 28-03-2018 IPR011032 GroES-like CNX65_RS22145 c5a82bfdcd3ccedfffd26195974b5e21 303 Pfam PF00107 Zinc-binding dehydrogenase 143 236 3.5E-12 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS22145 c5a82bfdcd3ccedfffd26195974b5e21 303 Gene3D G3DSA:3.90.180.10 1 140 9.7E-33 T 28-03-2018 CNX65_RS22145 c5a82bfdcd3ccedfffd26195974b5e21 303 SMART SM00829 12 300 2.6E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS22145 c5a82bfdcd3ccedfffd26195974b5e21 303 Gene3D G3DSA:3.40.50.720 141 244 3.2E-17 T 28-03-2018 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Gene3D G3DSA:3.30.300.30 389 502 3.1E-29 T 28-03-2018 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Pfam PF00501 AMP-binding enzyme 14 394 2.3E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Gene3D G3DSA:2.30.38.10 303 384 1.3E-21 T 28-03-2018 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Pfam PF00550 Phosphopantetheine attachment site 501 564 8.0E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Gene3D G3DSA:1.10.1200.10 503 574 2.4E-16 T 28-03-2018 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 SUPERFAMILY SSF47336 491 564 4.71E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Pfam PF13193 AMP-binding enzyme C-terminal domain 402 471 2.3E-5 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS12630 fba2d41368afa619830264328465d4de 592 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 35 418 3.8E-111 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Gene3D G3DSA:3.40.50.980 8 147 5.0E-33 T 28-03-2018 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 SUPERFAMILY SSF56801 4 507 8.37E-132 T 28-03-2018 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 Gene3D G3DSA:3.40.50.980 148 296 1.2E-35 T 28-03-2018 CNX65_RS12630 fba2d41368afa619830264328465d4de 592 ProSitePatterns PS00455 Putative AMP-binding domain signature. 146 157 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS00165 7365b80f243f49d373b68a1b591e8ed2 395 Gene3D G3DSA:3.20.20.10 23 275 7.4E-40 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS00165 7365b80f243f49d373b68a1b591e8ed2 395 Pfam PF01168 Alanine racemase, N-terminal domain 21 268 3.8E-14 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS00165 7365b80f243f49d373b68a1b591e8ed2 395 SUPERFAMILY SSF51419 22 270 9.49E-21 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 SUPERFAMILY SSF48008 90 217 3.66E-23 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 SMART SM00345 15 74 8.0E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 SMART SM00895 94 216 9.4E-17 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 Gene3D G3DSA:1.20.120.530 87 223 3.1E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 34 48 3.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 64 3.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 Gene3D G3DSA:1.10.10.10 3 76 7.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 Pfam PF07729 FCD domain 94 207 3.4E-20 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 SUPERFAMILY SSF46785 6 87 3.55E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28850 1453eae98b19da0fc003a4b76e946cf7 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.0E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS21725 7b56f9efcf958b972bdf2a42fb59443d 231 Gene3D G3DSA:1.10.10.60 5 44 1.9E-14 T 28-03-2018 CNX65_RS21725 7b56f9efcf958b972bdf2a42fb59443d 231 ProSitePatterns PS01081 TetR-type HTH domain signature. 27 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS21725 7b56f9efcf958b972bdf2a42fb59443d 231 SUPERFAMILY SSF46689 9 82 5.49E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21725 7b56f9efcf958b972bdf2a42fb59443d 231 Gene3D G3DSA:1.10.260.40 45 209 6.6E-9 T 28-03-2018 CNX65_RS21725 7b56f9efcf958b972bdf2a42fb59443d 231 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 5.7E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21725 7b56f9efcf958b972bdf2a42fb59443d 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21725 7b56f9efcf958b972bdf2a42fb59443d 231 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS28630 fbf10e3dcfae4298c02f2833cc13a679 174 Gene3D G3DSA:3.30.300.70 5 86 2.2E-22 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CNX65_RS28630 fbf10e3dcfae4298c02f2833cc13a679 174 Pfam PF17384 RimP C-terminal SH3 domain 92 153 7.0E-8 T 28-03-2018 IPR028998 Ribosome maturation factor RimP, C-terminal CNX65_RS28630 fbf10e3dcfae4298c02f2833cc13a679 174 SUPERFAMILY SSF75420 9 89 1.57E-17 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CNX65_RS28630 fbf10e3dcfae4298c02f2833cc13a679 174 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 11 153 19.578 T 28-03-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 CNX65_RS28630 fbf10e3dcfae4298c02f2833cc13a679 174 Pfam PF02576 RimP N-terminal domain 17 89 1.2E-17 T 28-03-2018 IPR028989 Ribosome maturation factor RimP, N-terminal CNX65_RS05220 19e2348d788663c6c43eb08c92a5f3c3 364 Gene3D G3DSA:3.40.50.2300 23 149 4.8E-17 T 28-03-2018 CNX65_RS05220 19e2348d788663c6c43eb08c92a5f3c3 364 SUPERFAMILY SSF53822 34 300 7.74E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS05220 19e2348d788663c6c43eb08c92a5f3c3 364 Gene3D G3DSA:3.40.50.2300 150 293 1.8E-26 T 28-03-2018 CNX65_RS05220 19e2348d788663c6c43eb08c92a5f3c3 364 Pfam PF13407 Periplasmic binding protein domain 36 296 5.7E-51 T 28-03-2018 IPR025997 Periplasmic binding protein CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 Gene3D G3DSA:1.10.260.40 7 63 7.7E-16 T 28-03-2018 CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 Gene3D G3DSA:3.40.50.2300 64 172 8.5E-17 T 28-03-2018 CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 Gene3D G3DSA:3.40.50.2300 173 349 1.4E-43 T 28-03-2018 CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 SUPERFAMILY SSF47413 7 67 7.13E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 SMART SM00354 8 79 1.6E-10 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 SUPERFAMILY SSF53822 82 347 2.36E-44 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 53 1.1E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS05570 81540420f0ebe0818a90440ecda89e71 350 Pfam PF13377 Periplasmic binding protein-like domain 177 346 8.8E-33 T 28-03-2018 CNX65_RS17685 ab00620d65c874cc08e434e98d3a97b4 193 SUPERFAMILY SSF48498 80 188 1.81E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS17685 ab00620d65c874cc08e434e98d3a97b4 193 Gene3D G3DSA:1.10.10.60 3 62 1.4E-15 T 28-03-2018 CNX65_RS17685 ab00620d65c874cc08e434e98d3a97b4 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 60 4.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS17685 ab00620d65c874cc08e434e98d3a97b4 193 Gene3D G3DSA:1.10.357.10 63 193 1.1E-16 T 28-03-2018 CNX65_RS17685 ab00620d65c874cc08e434e98d3a97b4 193 SUPERFAMILY SSF46689 9 75 7.7E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 TIGRFAM TIGR01391 dnaG: DNA primase 5 422 2.0E-111 T 28-03-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Gene3D G3DSA:3.90.980.10 110 243 5.8E-39 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Pfam PF13662 Toprim domain 263 334 2.5E-16 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Gene3D G3DSA:1.10.860.10 463 611 4.3E-26 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 SUPERFAMILY SSF57783 4 100 1.07E-31 T 28-03-2018 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Pfam PF08278 DNA primase DnaG DnaB-binding 481 607 1.5E-23 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Gene3D G3DSA:3.90.580.10 1 102 6.0E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Pfam PF01807 CHC2 zinc finger 7 101 1.8E-32 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 SUPERFAMILY SSF56731 117 430 3.4E-92 T 28-03-2018 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 SMART SM00400 37 91 5.7E-35 T 28-03-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Hamap MF_00974 DNA primase [dnaG]. 4 613 25.717 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 PIRSF PIRSF002811 2 619 1.2E-144 T 28-03-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Gene3D G3DSA:3.40.1360.10 244 373 1.2E-29 T 28-03-2018 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 SMART SM00766 480 608 3.8E-15 T 28-03-2018 IPR013173 DNA primase DnaG, DnaB-binding domain GO:0003896|GO:0006269 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Pfam PF08275 DNA primase catalytic core, N-terminal domain 127 254 6.6E-34 T 28-03-2018 IPR013264 DNA primase, catalytic core, N-terminal CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 SMART SM00493 262 339 1.8E-12 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Gene3D G3DSA:1.20.50.20 374 427 9.5E-17 T 28-03-2018 CNX65_RS06345 e8b845708f0c461c9deb5b4461a9486b 629 Pfam PF10410 DnaB-helicase binding domain of primase 375 430 2.0E-17 T 28-03-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 CNX65_RS32855 7408b33ec2c58ddfa956c5c24e7d0d24 313 SUPERFAMILY SSF103481 202 293 1.14E-7 T 28-03-2018 CNX65_RS32855 7408b33ec2c58ddfa956c5c24e7d0d24 313 TIGRFAM TIGR00688 rarD: protein RarD 21 269 5.3E-57 T 28-03-2018 IPR004626 RarD protein GO:0005215|GO:0005887|GO:0006810 CNX65_RS32855 7408b33ec2c58ddfa956c5c24e7d0d24 313 Pfam PF00892 EamA-like transporter family 21 154 3.4E-10 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS32855 7408b33ec2c58ddfa956c5c24e7d0d24 313 SUPERFAMILY SSF103481 55 156 1.77E-11 T 28-03-2018 CNX65_RS02340 31569341a1e13b5e33730d7eec90619a 202 SUPERFAMILY SSF52540 20 194 2.37E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02340 31569341a1e13b5e33730d7eec90619a 202 Pfam PF03029 Conserved hypothetical ATP binding protein 26 194 2.9E-26 T 28-03-2018 IPR004130 GPN-loop GTPase CNX65_RS02340 31569341a1e13b5e33730d7eec90619a 202 Gene3D G3DSA:3.40.50.300 9 200 4.1E-19 T 28-03-2018 CNX65_RS13630 07dbd42c778f88332546094d7235c235 450 Gene3D G3DSA:3.20.20.70 134 394 6.0E-6 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS13630 07dbd42c778f88332546094d7235c235 450 SUPERFAMILY SSF102114 151 347 1.57E-6 T 28-03-2018 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 SUPERFAMILY SSF53223 5 124 4.8E-34 T 28-03-2018 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 Hamap MF_01576 Bifunctional protein FolD [folD]. 6 285 35.722 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 126 283 2.6E-59 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 9 121 2.0E-33 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 36 58 2.0E-63 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 77 104 2.0E-63 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 258 276 2.0E-63 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 208 237 2.0E-63 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 112 133 2.0E-63 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 157 177 2.0E-63 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 Gene3D G3DSA:3.40.50.720 143 266 1.2E-29 T 28-03-2018 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 Gene3D G3DSA:3.40.50.10860 16 142 4.5E-41 T 28-03-2018 CNX65_RS31885 7faff16bfd2bf5e741302054fe55412d 288 SUPERFAMILY SSF51735 125 284 5.99E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14615 dcc5fffd473333511da5cc250814810c 330 Gene3D G3DSA:3.40.50.2000 1 154 5.7E-14 T 28-03-2018 CNX65_RS14615 dcc5fffd473333511da5cc250814810c 330 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 180 293 1.8E-11 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CNX65_RS14615 dcc5fffd473333511da5cc250814810c 330 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 156 296 3.4E-34 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CNX65_RS14615 dcc5fffd473333511da5cc250814810c 330 SUPERFAMILY SSF53756 1 326 9.77E-64 T 28-03-2018 CNX65_RS14615 dcc5fffd473333511da5cc250814810c 330 Gene3D G3DSA:3.40.50.2000 155 311 2.8E-38 T 28-03-2018 CNX65_RS32790 58cb1eb2cb7a386f39836d950a577a33 163 Pfam PF04461 Protein of unknown function (DUF520) 4 163 5.3E-60 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CNX65_RS32790 58cb1eb2cb7a386f39836d950a577a33 163 Gene3D G3DSA:3.30.70.860 98 163 1.4E-30 T 28-03-2018 IPR035571 UPF0234/UPF0381 domain CNX65_RS32790 58cb1eb2cb7a386f39836d950a577a33 163 Gene3D G3DSA:3.30.70.990 12 97 5.2E-28 T 28-03-2018 IPR035570 UPF0234 N-terminal domain CNX65_RS32790 58cb1eb2cb7a386f39836d950a577a33 163 SUPERFAMILY SSF89963 92 163 2.88E-24 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CNX65_RS32790 58cb1eb2cb7a386f39836d950a577a33 163 SUPERFAMILY SSF89963 4 88 1.05E-25 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CNX65_RS32790 58cb1eb2cb7a386f39836d950a577a33 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 3 163 24.937 T 28-03-2018 IPR007551 Protein of unknown function DUF520 CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 Gene3D G3DSA:3.30.420.40 251 319 5.9E-4 T 28-03-2018 CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 Gene3D G3DSA:3.90.870.10 386 596 1.5E-4 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 Pfam PF02543 Carbamoyltransferase N-terminus 23 342 4.0E-57 T 28-03-2018 IPR003696 Carbamoyltransferase GO:0003824|GO:0009058 CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 Gene3D G3DSA:3.30.420.40 1 151 1.3E-24 T 28-03-2018 CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 SUPERFAMILY SSF53067 131 215 1.36E-11 T 28-03-2018 CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 SUPERFAMILY SSF53067 34 95 1.36E-11 T 28-03-2018 CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 SUPERFAMILY SSF53067 249 343 1.36E-11 T 28-03-2018 CNX65_RS16240 0d395e852aa466acfc720b8ff4c4db5d 670 Pfam PF16861 Carbamoyltransferase C-terminus 400 572 9.9E-65 T 28-03-2018 IPR031730 Carbamoyltransferase, C-terminal CNX65_RS14825 7d597ae9ba66fbaac608bc7e2cc961f0 220 Gene3D G3DSA:3.10.350.10 160 217 6.6E-10 T 28-03-2018 CNX65_RS14825 7d597ae9ba66fbaac608bc7e2cc961f0 220 Pfam PF01476 LysM domain 167 213 1.2E-6 T 28-03-2018 IPR018392 LysM domain CNX65_RS28360 3ed905b62870307047923f4ced24dd6f 197 SUPERFAMILY SSF88659 120 192 3.92E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS28360 3ed905b62870307047923f4ced24dd6f 197 Gene3D G3DSA:1.10.1740.10 13 115 2.3E-20 T 28-03-2018 CNX65_RS28360 3ed905b62870307047923f4ced24dd6f 197 SUPERFAMILY SSF88946 15 122 2.75E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS28360 3ed905b62870307047923f4ced24dd6f 197 Pfam PF04542 Sigma-70 region 2 37 105 2.6E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS28360 3ed905b62870307047923f4ced24dd6f 197 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 189 3.0E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS28360 3ed905b62870307047923f4ced24dd6f 197 Gene3D G3DSA:1.10.10.10 116 197 3.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28360 3ed905b62870307047923f4ced24dd6f 197 Pfam PF08281 Sigma-70, region 4 136 187 1.6E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 SUPERFAMILY SSF46785 5 77 3.52E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 Pfam PF09339 IclR helix-turn-helix domain 7 58 1.5E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 Pfam PF01614 Bacterial transcriptional regulator 120 244 1.8E-35 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 Gene3D G3DSA:3.30.450.40 73 249 2.4E-57 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 TIGRFAM TIGR02431 pcaR_pcaU: beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family 2 247 2.8E-99 T 28-03-2018 IPR012794 Beta-ketoadipate transcriptional regulator, PcaR/PcaU/PobR GO:0003677|GO:0045893|GO:0046278 CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 SMART SM00346 5 93 2.1E-30 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 SUPERFAMILY SSF55781 69 247 8.5E-49 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS25245 7b12a4c0fd855fd7ee861ce8234545cc 249 Gene3D G3DSA:1.10.10.10 1 72 5.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 244 261 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 442 458 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 292 310 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 460 477 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 185 206 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 314 327 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 156 173 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 PRINTS PR00738 Glycosyl hydrolase family 20 signature 114 134 4.2E-48 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 Gene3D G3DSA:3.30.379.10 18 150 4.6E-26 T 28-03-2018 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 SUPERFAMILY SSF51445 162 507 2.95E-109 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 162 328 1.0E-59 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 336 478 1.1E-25 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 SUPERFAMILY SSF55545 19 161 4.97E-26 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 Gene3D G3DSA:3.20.20.80 151 511 9.6E-121 T 28-03-2018 CNX65_RS05475 43dd9f2a2e10f7452761e1045abc01d0 515 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 26 158 1.4E-19 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS19535 d95e84e5115cf8097e7429587158b2d6 301 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 73 89 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CNX65_RS19535 d95e84e5115cf8097e7429587158b2d6 301 ProSitePatterns PS01174 Lipolytic enzymes "G-D-X-G" family, putative serine active site. 139 151 - T 28-03-2018 IPR033140 Lipase, GDXG, putative serine active site CNX65_RS19535 d95e84e5115cf8097e7429587158b2d6 301 SUPERFAMILY SSF53474 25 291 5.4E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19535 d95e84e5115cf8097e7429587158b2d6 301 Gene3D G3DSA:3.40.50.1820 28 297 5.9E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19535 d95e84e5115cf8097e7429587158b2d6 301 Pfam PF07859 alpha/beta hydrolase fold 73 266 4.7E-45 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CNX65_RS08120 eb5ae6fb758f3fe0bf3b5e73c3fe6892 294 SMART SM00382 31 217 1.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08120 eb5ae6fb758f3fe0bf3b5e73c3fe6892 294 Pfam PF00005 ABC transporter 23 159 4.0E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS08120 eb5ae6fb758f3fe0bf3b5e73c3fe6892 294 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS08120 eb5ae6fb758f3fe0bf3b5e73c3fe6892 294 SUPERFAMILY SSF52540 6 220 2.17E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08120 eb5ae6fb758f3fe0bf3b5e73c3fe6892 294 Gene3D G3DSA:3.40.50.300 3 237 1.8E-61 T 28-03-2018 CNX65_RS22245 f500f282bb3c5f7773ec5272485ff093 241 Pfam PF08685 GON domain 100 206 2.0E-8 T 28-03-2018 IPR012314 Peptidase M12B, GON-ADAMTSs GO:0004222|GO:0008270 Reactome: R-HSA-5083635|Reactome: R-HSA-5173214 CNX65_RS22245 f500f282bb3c5f7773ec5272485ff093 241 Pfam PF08685 GON domain 36 91 1.5E-6 T 28-03-2018 IPR012314 Peptidase M12B, GON-ADAMTSs GO:0004222|GO:0008270 Reactome: R-HSA-5083635|Reactome: R-HSA-5173214 CNX65_RS21710 3767701b42155f77593984f25f97243e 156 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 47 2.0E-13 T 28-03-2018 CNX65_RS21710 3767701b42155f77593984f25f97243e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.1E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS21710 3767701b42155f77593984f25f97243e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.1E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS21710 3767701b42155f77593984f25f97243e 156 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.1E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS21710 3767701b42155f77593984f25f97243e 156 Pfam PF01037 Lrp/AsnC ligand binding domain 74 139 6.1E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS21710 3767701b42155f77593984f25f97243e 156 SUPERFAMILY SSF46785 1 60 1.36E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21710 3767701b42155f77593984f25f97243e 156 Gene3D G3DSA:1.10.10.10 1 52 2.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21710 3767701b42155f77593984f25f97243e 156 Gene3D G3DSA:3.30.70.920 53 138 2.7E-14 T 28-03-2018 CNX65_RS21710 3767701b42155f77593984f25f97243e 156 SUPERFAMILY SSF54909 63 142 4.02E-11 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS21710 3767701b42155f77593984f25f97243e 156 SMART SM00344 1 110 2.3E-27 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 SMART SM00846 3 153 2.5E-85 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 SUPERFAMILY SSF55347 153 314 8.04E-71 T 28-03-2018 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 147 165 1.5E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 230 247 1.5E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 270 285 1.5E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 174 190 1.5E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 111 124 1.5E-35 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 PIRSF PIRSF000149 1 334 5.3E-131 T 28-03-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 103 2.1E-36 T 28-03-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 SUPERFAMILY SSF51735 3 169 1.0E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 Gene3D G3DSA:3.30.360.10 163 315 4.6E-67 T 28-03-2018 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 158 313 5.5E-68 T 28-03-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 151 158 - T 28-03-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 Gene3D G3DSA:3.40.50.720 1 162 1.3E-71 T 28-03-2018 CNX65_RS25865 83da675665e7eae4333bc5befe60fd51 334 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 1.1E-130 T 28-03-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS31510 9386db57d6b527034477d1e630afea11 270 Pfam PF01048 Phosphorylase superfamily 31 267 4.4E-42 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CNX65_RS31510 9386db57d6b527034477d1e630afea11 270 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 85 126 - T 28-03-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 CNX65_RS31510 9386db57d6b527034477d1e630afea11 270 Gene3D G3DSA:3.40.50.1580 3 270 2.2E-63 T 28-03-2018 CNX65_RS31510 9386db57d6b527034477d1e630afea11 270 TIGRFAM TIGR01698 PUNP: purine nucleotide phosphorylase 31 267 4.2E-102 T 28-03-2018 IPR011269 Putative purine nucleotide phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 CNX65_RS31510 9386db57d6b527034477d1e630afea11 270 SUPERFAMILY SSF53167 16 268 6.82E-78 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CNX65_RS31510 9386db57d6b527034477d1e630afea11 270 PIRSF PIRSF000477 3 270 1.1E-92 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CNX65_RS31510 9386db57d6b527034477d1e630afea11 270 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 31 268 3.0E-79 T 28-03-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 Gene3D G3DSA:1.10.260.40 2 54 5.2E-15 T 28-03-2018 CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 SMART SM00354 1 68 1.3E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 Gene3D G3DSA:3.40.50.2300 178 323 7.6E-25 T 28-03-2018 CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 SUPERFAMILY SSF53822 55 306 2.57E-38 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 SUPERFAMILY SSF47413 2 52 7.78E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 46 3.0E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 Gene3D G3DSA:3.40.50.2300 55 177 5.3E-26 T 28-03-2018 CNX65_RS09190 04b3b26550fd23f45ccc88b08f1e4415 323 Pfam PF13377 Periplasmic binding protein-like domain 166 322 2.0E-26 T 28-03-2018 CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 SUPERFAMILY SSF88946 6 89 7.06E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 Gene3D G3DSA:1.10.1740.10 3 78 1.6E-12 T 28-03-2018 CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 156 7.9E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 5 157 1.3E-43 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 SUPERFAMILY SSF88659 95 157 1.27E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 Gene3D G3DSA:1.10.10.10 79 159 4.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 Pfam PF04542 Sigma-70 region 2 19 77 5.1E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25530 5e932d6672c4908e2cd1138fce867f18 171 Pfam PF08281 Sigma-70, region 4 101 152 3.3E-14 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30405 37a8b07a453151278f9c8d43bc361a2f 293 Pfam PF00296 Luciferase-like monooxygenase 7 206 2.8E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS30405 37a8b07a453151278f9c8d43bc361a2f 293 SUPERFAMILY SSF51679 1 288 6.41E-52 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS30405 37a8b07a453151278f9c8d43bc361a2f 293 Gene3D G3DSA:3.20.20.30 1 234 2.9E-57 T 28-03-2018 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 Gene3D G3DSA:1.10.1040.10 623 689 1.5E-7 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 331 510 2.5E-58 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 514 595 4.0E-12 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 Pfam PF00378 Enoyl-CoA hydratase/isomerase 47 226 2.1E-23 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 SUPERFAMILY SSF51735 328 512 5.22E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 SUPERFAMILY SSF48179 512 612 8.5E-16 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 SUPERFAMILY SSF52096 244 320 1.37E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 SUPERFAMILY SSF52096 27 211 1.37E-42 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 SUPERFAMILY SSF48179 624 686 8.25E-12 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 Gene3D G3DSA:1.10.1040.10 513 598 8.1E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 Gene3D G3DSA:3.90.226.10 16 284 4.4E-40 T 28-03-2018 CNX65_RS07655 1afb57f8cc402c9cf787188f5a321a13 700 Gene3D G3DSA:3.40.50.720 285 512 1.0E-56 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Pfam PF03704 Bacterial transcriptional activator domain 114 255 1.9E-35 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Pfam PF00486 Transcriptional regulatory protein, C terminal 41 106 8.4E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Gene3D G3DSA:1.10.150.200 762 809 3.7E-9 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SUPERFAMILY SSF48452 717 912 3.46E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM00382 301 439 0.0018 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SUPERFAMILY SSF46894 19 107 1.08E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM00862 34 107 9.2E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SUPERFAMILY SSF48452 114 273 5.57E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Gene3D G3DSA:1.10.10.10 10 110 3.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Pfam PF13424 Tetratricopeptide repeat 842 911 1.1E-10 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Pfam PF13424 Tetratricopeptide repeat 761 827 5.6E-9 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Gene3D G3DSA:1.25.40.10 851 919 1.4E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Gene3D G3DSA:1.25.40.10 111 274 7.6E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Gene3D G3DSA:3.40.50.300 275 421 7.0E-18 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Gene3D G3DSA:1.25.40.10 810 850 1.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 PRINTS PR00364 Disease resistance protein signature 382 396 4.3E-7 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 PRINTS PR00364 Disease resistance protein signature 304 319 4.3E-7 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 PRINTS PR00364 Disease resistance protein signature 470 484 4.3E-7 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM01043 114 255 5.0E-46 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Pfam PF00931 NB-ARC domain 301 538 9.7E-11 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM00028 880 913 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM00028 760 793 3.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM00028 800 833 1.9 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM00028 722 755 20.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SMART SM00028 840 873 7.8 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 Gene3D G3DSA:3.30.70.100 701 761 7.2E-5 T 28-03-2018 CNX65_RS30625 506a29a883f0d2d800f551bca957dd35 931 SUPERFAMILY SSF52540 277 534 9.61E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 73 92 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 113 132 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 343 358 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 29 46 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 47 66 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 94 112 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 6 25 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 386 405 2.9E-51 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 Gene3D G3DSA:1.20.1340.10 1 81 6.3E-36 T 28-03-2018 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 35 401 1.3E-99 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 Gene3D G3DSA:3.90.1150.10 359 462 1.2E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 Gene3D G3DSA:3.40.640.10 82 358 4.1E-64 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS27855 54b2b2e4f9263fc3103f53c1bd24a5c6 462 SUPERFAMILY SSF53383 1 462 2.13E-132 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 Gene3D G3DSA:1.10.10.10 4 79 5.6E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 SMART SM00420 9 61 9.4E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 Gene3D G3DSA:3.40.50.1360 80 242 1.1E-32 T 28-03-2018 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 SUPERFAMILY SSF100950 80 237 2.86E-24 T 28-03-2018 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 SUPERFAMILY SSF46785 7 62 6.72E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 SMART SM01134 76 237 7.4E-54 T 28-03-2018 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 9.4E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 9.4E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 Pfam PF08220 DeoR-like helix-turn-helix domain 9 63 2.3E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS18685 409b05a1fb8d229a05a916079260c37c 272 Pfam PF00455 DeoR C terminal sensor domain 79 235 3.5E-42 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CNX65_RS32220 c2263178f2a906c946ff0a6f5abe5a01 147 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 28-03-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 CNX65_RS32220 c2263178f2a906c946ff0a6f5abe5a01 147 Gene3D G3DSA:3.90.1180.10 1 147 6.2E-60 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32220 c2263178f2a906c946ff0a6f5abe5a01 147 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 7 141 2.4E-60 T 28-03-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32220 c2263178f2a906c946ff0a6f5abe5a01 147 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 27.727 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32220 c2263178f2a906c946ff0a6f5abe5a01 147 PIRSF PIRSF002181 3 147 1.5E-48 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32220 c2263178f2a906c946ff0a6f5abe5a01 147 Pfam PF00572 Ribosomal protein L13 15 138 3.5E-54 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32220 c2263178f2a906c946ff0a6f5abe5a01 147 SUPERFAMILY SSF52161 4 143 5.36E-57 T 28-03-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 CNX65_RS18270 da70c54b727844a820dad96b98f3284b 546 Pfam PF01565 FAD binding domain 81 211 1.3E-16 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS18270 da70c54b727844a820dad96b98f3284b 546 Gene3D G3DSA:3.30.43.10 57 135 4.5E-11 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS18270 da70c54b727844a820dad96b98f3284b 546 Gene3D G3DSA:3.30.465.10 136 280 1.2E-22 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS18270 da70c54b727844a820dad96b98f3284b 546 SUPERFAMILY SSF56176 55 254 3.27E-32 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS18270 da70c54b727844a820dad96b98f3284b 546 Pfam PF08031 Berberine and berberine like 490 542 8.5E-17 T 28-03-2018 IPR012951 Berberine/berberine-like GO:0016491|GO:0050660|GO:0055114 CNX65_RS12160 68eff94680482cb07513da86e2005ab6 302 SUPERFAMILY SSF47413 29 79 4.02E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS12160 68eff94680482cb07513da86e2005ab6 302 Pfam PF13560 Helix-turn-helix domain 5 84 2.6E-13 T 28-03-2018 CNX65_RS12160 68eff94680482cb07513da86e2005ab6 302 Gene3D G3DSA:1.10.260.40 1 84 3.8E-12 T 28-03-2018 CNX65_RS12160 68eff94680482cb07513da86e2005ab6 302 SMART SM00530 5 81 0.0019 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 Gene3D G3DSA:1.10.10.10 15 118 7.9E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 SMART SM00418 32 112 3.2E-33 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 Pfam PF01022 Bacterial regulatory protein, arsR family 39 88 1.9E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 SUPERFAMILY SSF46785 17 112 8.82E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 34 49 2.7E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 2.7E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 2.7E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17360 a64802df4a3c1c9acb5e90dda715bb82 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 2.7E-24 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS28030 ba3c130271d42af79b47be27a0a9ea8d 174 SUPERFAMILY SSF56399 8 172 6.55E-55 T 28-03-2018 CNX65_RS28030 ba3c130271d42af79b47be27a0a9ea8d 174 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 7 163 2.9E-37 T 28-03-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 CNX65_RS28030 ba3c130271d42af79b47be27a0a9ea8d 174 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 5 171 29.958 T 28-03-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 Pfam PF00106 short chain dehydrogenase 6 188 9.2E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 SUPERFAMILY SSF51735 3 242 7.59E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 Gene3D G3DSA:3.40.50.720 2 277 1.4E-59 T 28-03-2018 CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 1.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 234 1.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 1.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 1.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 1.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 7.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 7.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17530 0140394c13767095abe394d41fc372d7 288 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 7.3E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 65 7.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 SUPERFAMILY SSF46689 10 79 3.69E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 Gene3D G3DSA:1.10.10.60 3 42 3.2E-12 T 28-03-2018 CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 42 65 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 21 34 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 Gene3D G3DSA:1.10.260.40 43 69 1.5E-13 T 28-03-2018 CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 Gene3D G3DSA:1.10.357.10 70 188 1.5E-10 T 28-03-2018 CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 SUPERFAMILY SSF48498 80 186 1.58E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS16395 d896b1cb43812258d425f78617db16b4 188 Pfam PF16859 Bacterial transcriptional repressor C-terminal 80 182 3.9E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS03310 b3d42b96a414890ccb24c1c44a1af89e 304 Gene3D G3DSA:1.10.287.1080 241 304 0.0083 T 28-03-2018 CNX65_RS03310 b3d42b96a414890ccb24c1c44a1af89e 304 TIGRFAM TIGR00444 mazG: MazG family protein 87 234 1.8E-44 T 28-03-2018 IPR011551 NTP pyrophosphohydrolase MazG CNX65_RS03310 b3d42b96a414890ccb24c1c44a1af89e 304 SUPERFAMILY SSF101386 84 181 4.74E-23 T 28-03-2018 CNX65_RS03310 b3d42b96a414890ccb24c1c44a1af89e 304 Gene3D G3DSA:1.10.287.1080 77 205 3.7E-40 T 28-03-2018 CNX65_RS03310 b3d42b96a414890ccb24c1c44a1af89e 304 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 103 178 2.1E-25 T 28-03-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 Pfam PF00072 Response regulator receiver domain 11 123 8.2E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 SMART SM00448 9 123 3.0E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 Gene3D G3DSA:3.60.40.10 284 513 1.3E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 Gene3D G3DSA:3.30.450.40 133 283 9.9E-5 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 SUPERFAMILY SSF81606 320 509 2.38E-10 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 Gene3D G3DSA:3.40.50.2300 1 132 4.4E-32 T 28-03-2018 CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 SUPERFAMILY SSF52172 4 137 1.29E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 332 513 2.0E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18715 2b21c04cac298efa7a59f95bc8a6147d 523 SMART SM00331 306 513 3.5E-29 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 Pfam PF01595 Domain of unknown function DUF21 10 188 8.5E-45 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 SUPERFAMILY SSF54631 210 343 6.22E-24 T 28-03-2018 CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 Pfam PF00571 CBS domain 280 326 1.7E-6 T 28-03-2018 IPR000644 CBS domain CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 Pfam PF00571 CBS domain 216 266 2.9E-5 T 28-03-2018 IPR000644 CBS domain CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 SUPERFAMILY SSF56176 340 426 4.64E-13 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 SMART SM01091 341 422 1.3E-14 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 Pfam PF03471 Transporter associated domain 342 420 2.3E-13 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 Gene3D G3DSA:3.10.580.10 190 332 3.1E-29 T 28-03-2018 CNX65_RS24530 ecf27fbca9cf428b851b6065bf17562a 440 Gene3D G3DSA:3.30.465.10 333 422 1.0E-18 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 SUPERFAMILY SSF52518 242 506 1.62E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 523 587 8.1E-8 T 28-03-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 Gene3D G3DSA:3.40.50.970 242 508 7.0E-60 T 28-03-2018 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 267 483 7.2E-54 T 28-03-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 30 218 2.5E-25 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 Gene3D G3DSA:3.40.920.10 19 235 1.9E-40 T 28-03-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 SUPERFAMILY SSF52922 523 622 1.88E-15 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 SUPERFAMILY SSF53323 24 232 1.18E-16 T 28-03-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 22 615 3.1E-201 T 28-03-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 CNX65_RS32840 ae0a2ffa7061d958c9568a70dc0d029c 627 Gene3D G3DSA:3.40.50.920 519 624 1.0E-9 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00385 P450 superfamily signature 278 289 1.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00385 P450 superfamily signature 354 365 1.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00385 P450 superfamily signature 241 258 1.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00385 P450 superfamily signature 345 354 1.5E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 SUPERFAMILY SSF48264 23 405 2.88E-91 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 Gene3D G3DSA:1.10.630.10 8 405 2.3E-69 T 28-03-2018 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 Pfam PF00067 Cytochrome P450 219 370 8.7E-18 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 345 354 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 354 365 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 324 339 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 296 323 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 159 174 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 142 158 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 196 218 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 278 289 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 PRINTS PR00359 B-class P450 signature 95 106 6.8E-56 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14605 092f3d54022b8e1ee9d770cdaab8d713 405 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 347 356 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Pfam PF02436 Conserved carboxylase domain 821 1008 3.4E-53 T 28-03-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Pfam PF02785 Biotin carboxylase C-terminal domain 339 446 7.4E-34 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Gene3D G3DSA:3.10.600.10 965 1042 8.0E-23 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 SUPERFAMILY SSF51569 517 829 6.59E-77 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 SUPERFAMILY SSF51230 1049 1125 8.38E-18 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Gene3D G3DSA:3.20.20.70 525 825 1.4E-72 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 SUPERFAMILY SSF51246 334 451 3.92E-37 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 SMART SM00878 339 446 2.2E-53 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Gene3D G3DSA:3.10.600.10 458 524 9.6E-11 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 SUPERFAMILY SSF56059 84 359 1.56E-69 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Gene3D G3DSA:2.40.50.100 1055 1125 3.3E-17 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Gene3D G3DSA:3.30.470.20 204 449 7.2E-100 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 111 8.5E-40 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 4 1125 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Gene3D G3DSA:3.30.1490.20 130 201 5.5E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Pfam PF00364 Biotin-requiring enzyme 1066 1124 4.9E-15 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Gene3D G3DSA:3.40.50.20 1 129 2.8E-45 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Pfam PF00682 HMGL-like 525 796 7.4E-31 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 1081 1098 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 117 322 1.5E-70 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 PIRSF PIRSF001594 1 1125 0.0 T 28-03-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 SUPERFAMILY SSF89000 826 991 3.92E-40 T 28-03-2018 CNX65_RS29345 fc9caec1ffc77380174558ed72d4e609 1125 SUPERFAMILY SSF52440 1 112 5.97E-41 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS04950 aba4ab42724d9f669f14713f249faf99 189 SUPERFAMILY SSF51182 9 184 2.14E-29 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS04950 aba4ab42724d9f669f14713f249faf99 189 Pfam PF03079 ARD/ARD' family 13 165 1.9E-24 T 28-03-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 CNX65_RS04950 aba4ab42724d9f669f14713f249faf99 189 Gene3D G3DSA:2.60.120.10 2 158 1.5E-27 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS04950 aba4ab42724d9f669f14713f249faf99 189 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 173 31.672 T 28-03-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.53+1.13.11.54|MetaCyc: PWY-4361|MetaCyc: PWY-5389 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 Pfam PF00742 Homoserine dehydrogenase 142 324 8.3E-66 T 28-03-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 SUPERFAMILY SSF55021 354 427 5.35E-13 T 28-03-2018 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 SUPERFAMILY SSF51735 9 163 3.45E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 Gene3D G3DSA:3.40.50.720 6 153 1.5E-29 T 28-03-2018 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 188 210 - T 28-03-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 Gene3D G3DSA:3.30.70.260 353 431 6.2E-21 T 28-03-2018 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 PIRSF PIRSF000098 9 435 4.8E-158 T 28-03-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 Gene3D G3DSA:3.30.360.10 154 308 6.6E-58 T 28-03-2018 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 Pfam PF01842 ACT domain 359 415 7.5E-11 T 28-03-2018 IPR002912 ACT domain CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 SUPERFAMILY SSF55347 142 311 1.24E-50 T 28-03-2018 CNX65_RS30300 155c2a55ba961d35f3fe919aad534dbd 437 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 18 134 1.8E-25 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CNX65_RS34155 84611f38bb152bc98c1f5a73842de384 331 SUPERFAMILY SSF49899 241 326 6.33E-22 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS34155 84611f38bb152bc98c1f5a73842de384 331 SUPERFAMILY SSF49899 97 200 6.33E-22 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS34155 84611f38bb152bc98c1f5a73842de384 331 Gene3D G3DSA:2.60.120.200 58 331 1.7E-20 T 28-03-2018 CNX65_RS34155 84611f38bb152bc98c1f5a73842de384 331 Pfam PF00722 Glycosyl hydrolases family 16 98 196 2.2E-9 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 PRINTS PR00046 Major sigma-70 factor signature 139 152 9.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 PRINTS PR00046 Major sigma-70 factor signature 308 323 9.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 PRINTS PR00046 Major sigma-70 factor signature 163 171 9.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 PRINTS PR00046 Major sigma-70 factor signature 323 334 9.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 PRINTS PR00046 Major sigma-70 factor signature 287 299 9.6E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 Pfam PF04545 Sigma-70, region 4 283 336 5.2E-16 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 Gene3D G3DSA:1.10.601.10 15 184 1.5E-70 T 28-03-2018 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 SUPERFAMILY SSF88946 49 185 3.27E-51 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 111 336 1.0E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 SUPERFAMILY SSF88659 188 262 2.43E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 Pfam PF00140 Sigma-70 factor, region 1.2 49 82 7.1E-15 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 139 152 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 308 334 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 Pfam PF04539 Sigma-70 region 3 195 270 1.1E-20 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 Gene3D G3DSA:1.10.10.10 185 235 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 Pfam PF04542 Sigma-70 region 2 115 185 4.1E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 Gene3D G3DSA:1.10.10.10 277 348 7.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16330 4488b6ae51d3e3427a663e66f7b091ec 348 SUPERFAMILY SSF88659 247 346 2.43E-23 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 Gene3D G3DSA:3.90.45.10 1 171 4.3E-57 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 Pfam PF01327 Polypeptide deformylase 4 158 7.3E-41 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 PRINTS PR01576 Peptide deformylase signature 97 108 1.9E-31 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 PRINTS PR01576 Peptide deformylase signature 109 127 1.9E-31 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 PRINTS PR01576 Peptide deformylase signature 128 157 1.9E-31 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 PRINTS PR01576 Peptide deformylase signature 33 62 1.9E-31 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 10 164 5.1E-37 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 SUPERFAMILY SSF56420 3 181 2.75E-53 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 Hamap MF_00163 Peptide deformylase [def]. 2 170 27.97 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS02165 169ef935f37c7ed59347f72bae1988f8 195 PIRSF PIRSF004749 1 177 6.3E-41 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS07695 ce81948355c684ab539da41bd67a296d 182 Pfam PF11452 Protein of unknown function (DUF3000) 8 179 4.5E-72 T 28-03-2018 IPR021555 Protein of unknown function DUF3000 CNX65_RS31590 8459122de08f0afe1e1ee0a69197eccc 141 Gene3D G3DSA:3.30.530.20 32 121 3.1E-6 T 28-03-2018 IPR023393 START-like domain CNX65_RS31590 8459122de08f0afe1e1ee0a69197eccc 141 SUPERFAMILY SSF55961 28 90 5.5E-6 T 28-03-2018 CNX65_RS02740 b9c1af6d8bc9b55400e9ef8657709af8 334 Pfam PF00107 Zinc-binding dehydrogenase 157 286 3.3E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS02740 b9c1af6d8bc9b55400e9ef8657709af8 334 Gene3D G3DSA:3.40.50.720 148 275 3.8E-26 T 28-03-2018 CNX65_RS02740 b9c1af6d8bc9b55400e9ef8657709af8 334 Pfam PF16884 N-terminal domain of oxidoreductase 6 112 1.4E-38 T 28-03-2018 CNX65_RS02740 b9c1af6d8bc9b55400e9ef8657709af8 334 SUPERFAMILY SSF51735 122 299 8.83E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02740 b9c1af6d8bc9b55400e9ef8657709af8 334 Gene3D G3DSA:3.90.180.10 1 147 5.4E-41 T 28-03-2018 CNX65_RS02740 b9c1af6d8bc9b55400e9ef8657709af8 334 SUPERFAMILY SSF50129 1 140 8.84E-41 T 28-03-2018 IPR011032 GroES-like CNX65_RS02740 b9c1af6d8bc9b55400e9ef8657709af8 334 SMART SM00829 18 332 2.0E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 Gene3D G3DSA:3.40.190.10 92 185 2.9E-19 T 28-03-2018 CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 Gene3D G3DSA:3.40.190.10 186 270 1.7E-14 T 28-03-2018 CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 Gene3D G3DSA:1.10.10.10 1 87 1.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 SUPERFAMILY SSF53850 92 294 5.84E-22 T 28-03-2018 CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 2.6E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 Pfam PF03466 LysR substrate binding domain 90 293 2.6E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 SUPERFAMILY SSF46785 8 114 1.82E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21275 e64b73ec1421f76371c10156d7a2be14 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 65 1.5E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 SMART SM01002 149 297 4.0E-84 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 SUPERFAMILY SSF52283 305 357 4.93E-65 T 28-03-2018 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 SUPERFAMILY SSF52283 2 137 4.93E-65 T 28-03-2018 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 Gene3D G3DSA:3.40.50.720 196 367 3.5E-42 T 28-03-2018 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 Gene3D G3DSA:3.40.50.720 1 176 1.3E-44 T 28-03-2018 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 5 137 4.5E-46 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 PIRSF PIRSF000183 1 367 1.3E-158 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 352 8.4E-81 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 173 198 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 2 358 2.0E-166 T 28-03-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 SMART SM01003 4 137 7.1E-77 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 Gene3D G3DSA:3.50.50.60 177 195 5.7E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30755 4199cd916d36a0316e03003f5bafc95d 368 SUPERFAMILY SSF51735 137 303 3.13E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 398 8.2E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 Gene3D G3DSA:3.40.47.10 1 271 7.2E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 ProSitePatterns PS00099 Thiolases active site. 381 394 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 SUPERFAMILY SSF53901 3 277 2.6E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 SUPERFAMILY SSF53901 278 399 8.4E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 ProSitePatterns PS00737 Thiolases signature 2. 346 362 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 Pfam PF00108 Thiolase, N-terminal domain 6 227 3.0E-45 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 PIRSF PIRSF000429 1 400 1.1E-115 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 Pfam PF02803 Thiolase, C-terminal domain 278 399 2.3E-46 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CNX65_RS27760 2344098e160e6305dcbf3a3e270b1197 400 Gene3D G3DSA:3.40.47.10 272 397 3.5E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS32960 54c431a006f3d142bf3a26b8eec7e344 170 Gene3D G3DSA:3.30.300.130 10 102 7.8E-18 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CNX65_RS32960 54c431a006f3d142bf3a26b8eec7e344 170 Pfam PF01883 Iron-sulfur cluster assembly protein 16 71 7.6E-12 T 28-03-2018 IPR002744 MIP18 family-like CNX65_RS32960 54c431a006f3d142bf3a26b8eec7e344 170 TIGRFAM TIGR02159 PA_CoA_Oxy4: phenylacetate-CoA oxygenase, PaaJ subunit 18 170 6.4E-56 T 28-03-2018 IPR011883 Phenylacetate-CoA oxygenase, PaaJ subunit CNX65_RS32960 54c431a006f3d142bf3a26b8eec7e344 170 SUPERFAMILY SSF117916 11 101 1.08E-19 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 Pfam PF01078 Magnesium chelatase, subunit ChlI 191 395 1.2E-81 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 Pfam PF13541 Subunit ChlI of Mg-chelatase 21 141 3.5E-34 T 28-03-2018 CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 Pfam PF13335 Magnesium chelatase, subunit ChlI C-terminal 405 500 3.7E-25 T 28-03-2018 IPR025158 Mg chelatase-related protein, C-terminal domain CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 Gene3D G3DSA:3.40.50.300 190 426 1.7E-23 T 28-03-2018 CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 SUPERFAMILY SSF52540 191 500 1.64E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 TIGRFAM TIGR00368 TIGR00368: Mg chelatase-like protein 7 500 4.4E-137 T 28-03-2018 IPR004482 Mg chelatase-related protein CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 SMART SM00382 211 393 7.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 Gene3D G3DSA:3.30.230.10 3 177 6.6E-37 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS29030 317d13ca388ece2273f264b5cabe9bba 506 SUPERFAMILY SSF54211 6 170 1.74E-33 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 Pfam PF01483 Proprotein convertase P-domain 483 563 3.2E-17 T 28-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 SUPERFAMILY SSF54897 68 138 1.53E-5 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 211 221 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 366 376 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 Gene3D G3DSA:3.30.70.80 63 141 1.5E-12 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 Gene3D G3DSA:2.60.120.260 442 563 6.8E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 PRINTS PR00723 Subtilisin serine protease family (S8) signature 207 220 3.3E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 PRINTS PR00723 Subtilisin serine protease family (S8) signature 169 188 3.3E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 PRINTS PR00723 Subtilisin serine protease family (S8) signature 365 381 3.3E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 Pfam PF00082 Subtilase family 176 404 1.4E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 Gene3D G3DSA:3.40.50.200 142 423 1.3E-74 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 SUPERFAMILY SSF49785 458 563 8.08E-19 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 SUPERFAMILY SSF52743 142 410 1.14E-73 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS12020 1a7dba22a416d58cb47219bbf938ec86 563 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 174 185 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS26655 9f84490cbd76cefb052b29d61ca3398c 188 Gene3D G3DSA:1.10.1660.10 24 186 2.1E-16 T 28-03-2018 CNX65_RS26655 9f84490cbd76cefb052b29d61ca3398c 188 SMART SM00422 30 102 1.9E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS26655 9f84490cbd76cefb052b29d61ca3398c 188 SUPERFAMILY SSF46955 33 118 1.79E-15 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS26655 9f84490cbd76cefb052b29d61ca3398c 188 Pfam PF13411 MerR HTH family regulatory protein 33 99 2.5E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS04790 c993dff78b7f66bc823c9676d27adeae 233 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 3 226 53.369 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CNX65_RS04790 c993dff78b7f66bc823c9676d27adeae 233 SUPERFAMILY SSF52402 4 231 3.97E-61 T 28-03-2018 CNX65_RS04790 c993dff78b7f66bc823c9676d27adeae 233 Gene3D G3DSA:3.40.50.620 2 233 1.1E-51 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS04790 c993dff78b7f66bc823c9676d27adeae 233 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 5 213 2.1E-58 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CNX65_RS04790 c993dff78b7f66bc823c9676d27adeae 233 Pfam PF06508 Queuosine biosynthesis protein QueC 5 220 3.6E-73 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CNX65_RS04790 c993dff78b7f66bc823c9676d27adeae 233 PIRSF PIRSF006293 1 232 8.5E-74 T 28-03-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Gene3D G3DSA:3.30.413.10 623 799 2.6E-39 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Gene3D G3DSA:3.50.50.60 100 248 4.5E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 288 3.6E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 671 687 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 SUPERFAMILY SSF51905 3 314 3.29E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Pfam PF04324 BFD-like [2Fe-2S] binding domain 419 468 1.1E-14 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 288 3.9E-6 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.9E-6 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 3.9E-6 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 240 254 3.9E-6 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 552 613 1.6E-10 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 TIGRFAM TIGR02374 nitri_red_nirB: nitrite reductase [NAD(P)H], large subunit 5 793 0.0 T 28-03-2018 IPR012744 Nitrite reductase [NAD(P)H] large subunit, NirB GO:0008942|GO:0042128|GO:0050660|GO:0050661|GO:0055114 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 SUPERFAMILY SSF56014 625 799 1.11E-51 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Gene3D G3DSA:3.90.480.10 459 620 9.6E-20 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 624 760 1.3E-20 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 3.8E-17 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 3.8E-17 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 97 115 3.8E-17 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.8E-17 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 3.8E-17 T 28-03-2018 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 SUPERFAMILY SSF55124 499 633 2.78E-24 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Gene3D G3DSA:3.50.50.60 1 99 7.9E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 Gene3D G3DSA:3.50.50.60 252 341 5.3E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00397 Sirohaem Fe-binding site signature 628 646 5.3E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PRINTS PR00397 Sirohaem Fe-binding site signature 671 689 5.3E-6 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS04135 f2f9b0a85e60e8ea2357d20e593bd7f5 834 PIRSF PIRSF037149 1 827 0.0 T 28-03-2018 IPR017121 Nitrite reductase [NAD(P)H], large subunit GO:0042128 CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 SMART SM00849 28 222 2.5E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 17 557 2.1E-145 T 28-03-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 Pfam PF00753 Metallo-beta-lactamase superfamily 25 180 1.9E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 368 414 3.4E-9 T 28-03-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 Hamap MF_01491 Ribonuclease J [rnj]. 11 559 40.172 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 SUPERFAMILY SSF56281 16 430 1.3E-91 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 Gene3D G3DSA:3.60.15.10 4 455 1.3E-63 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS28455 84b8dafce20df31a59ac4d6ab07c885b 559 PIRSF PIRSF004803 10 559 4.0E-194 T 28-03-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 CNX65_RS31320 0016fe464a42a998878434dfaa3b4573 863 SUPERFAMILY SSF88946 9 110 4.51E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS31320 0016fe464a42a998878434dfaa3b4573 863 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 184 1.4E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS31320 0016fe464a42a998878434dfaa3b4573 863 Pfam PF04542 Sigma-70 region 2 31 99 1.5E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS31320 0016fe464a42a998878434dfaa3b4573 863 Pfam PF13490 Putative zinc-finger 198 232 5.7E-8 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS31320 0016fe464a42a998878434dfaa3b4573 863 Gene3D G3DSA:1.10.10.10 100 188 1.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31320 0016fe464a42a998878434dfaa3b4573 863 SUPERFAMILY SSF88659 123 183 8.04E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS31320 0016fe464a42a998878434dfaa3b4573 863 Gene3D G3DSA:1.10.1740.10 10 99 4.6E-17 T 28-03-2018 CNX65_RS16080 691dff75ef25a130e872945061a9dc7d 334 Pfam PF16113 Enoyl-CoA hydratase/isomerase 13 334 1.9E-118 T 28-03-2018 IPR032259 Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type GO:0003860 Reactome: R-HSA-70895 CNX65_RS16080 691dff75ef25a130e872945061a9dc7d 334 SUPERFAMILY SSF52096 3 190 7.47E-60 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS16080 691dff75ef25a130e872945061a9dc7d 334 SUPERFAMILY SSF52096 248 319 7.47E-60 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS16080 691dff75ef25a130e872945061a9dc7d 334 Gene3D G3DSA:3.90.226.10 2 328 2.3E-86 T 28-03-2018 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 PIRSF PIRSF003095 1 444 4.1E-112 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Gene3D G3DSA:1.10.3120.10 226 395 6.3E-42 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 TIGRFAM TIGR00115 tig: trigger factor 12 417 1.6E-115 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Hamap MF_00303 Trigger factor [tig]. 1 424 18.855 T 28-03-2018 IPR005215 Trigger factor GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Pfam PF05697 Bacterial trigger factor protein (TF) 2 145 1.9E-38 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Gene3D G3DSA:1.10.4030.10 123 158 0.055 T 28-03-2018 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 SUPERFAMILY SSF109998 245 434 8.04E-41 T 28-03-2018 IPR027304 Trigger factor/SurA domain CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 157 215 8.8E-6 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Gene3D G3DSA:3.30.70.1050 1 119 1.9E-34 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 SUPERFAMILY SSF54534 133 244 1.87E-21 T 28-03-2018 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 SUPERFAMILY SSF102735 1 128 1.83E-33 T 28-03-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 258 418 7.2E-33 T 28-03-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 CNX65_RS05745 5949a03d0dbda1faef394b08b3ff9ff2 450 Gene3D G3DSA:3.10.50.40 159 225 4.2E-7 T 28-03-2018 CNX65_RS26110 a5a5390840afc7aa5147a8e3ba8277b5 190 Gene3D G3DSA:3.40.50.2020 10 190 1.6E-35 T 28-03-2018 CNX65_RS26110 a5a5390840afc7aa5147a8e3ba8277b5 190 SUPERFAMILY SSF53271 16 185 1.22E-40 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS26110 a5a5390840afc7aa5147a8e3ba8277b5 190 Pfam PF00156 Phosphoribosyl transferase domain 16 161 1.1E-21 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CNX65_RS26110 a5a5390840afc7aa5147a8e3ba8277b5 190 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 14 190 34.584 T 28-03-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 SUPERFAMILY SSF51905 3 195 8.91E-36 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 Gene3D G3DSA:3.50.50.60 1 103 6.5E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 SUPERFAMILY SSF51905 151 307 1.11E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 Pfam PF04324 BFD-like [2Fe-2S] binding domain 424 467 5.3E-12 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 Gene3D G3DSA:3.50.50.60 246 328 1.7E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 Gene3D G3DSA:3.50.50.60 104 240 8.8E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 6.8E-10 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 177 6.8E-10 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 274 281 6.8E-10 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 235 249 6.8E-10 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 298 4.2E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 Gene3D G3DSA:3.30.390.30 329 402 5.7E-5 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 234 250 5.6E-20 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 5.6E-20 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 5.6E-20 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.6E-20 T 28-03-2018 CNX65_RS04125 8fd6848687c7a8a57b97969e269d64fa 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 152 170 5.6E-20 T 28-03-2018 CNX65_RS09085 9c2bb99c0481a523ad4abe8c2c54df84 330 Gene3D G3DSA:3.90.1720.10 210 321 1.2E-29 T 28-03-2018 CNX65_RS09085 9c2bb99c0481a523ad4abe8c2c54df84 330 Pfam PF00877 NlpC/P60 family 228 311 3.9E-18 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CNX65_RS09085 9c2bb99c0481a523ad4abe8c2c54df84 330 SUPERFAMILY SSF54001 211 323 4.58E-31 T 28-03-2018 CNX65_RS09085 9c2bb99c0481a523ad4abe8c2c54df84 330 Gene3D G3DSA:1.20.120.330 11 199 4.7E-6 T 28-03-2018 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 275 282 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 SUPERFAMILY SSF51230 558 631 2.75E-19 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.2E-39 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Gene3D G3DSA:3.30.470.20 192 436 5.5E-97 T 28-03-2018 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 142 156 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 115 311 3.3E-59 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Gene3D G3DSA:3.30.1490.20 119 190 4.8E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Gene3D G3DSA:3.40.50.20 1 118 6.4E-47 T 28-03-2018 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 SUPERFAMILY SSF52440 1 113 7.19E-42 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 SUPERFAMILY SSF51246 317 431 9.42E-36 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 SMART SM00878 323 427 3.2E-49 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 SUPERFAMILY SSF56059 83 321 1.94E-63 T 28-03-2018 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Gene3D G3DSA:2.40.50.100 560 617 8.9E-16 T 28-03-2018 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Pfam PF02785 Biotin carboxylase C-terminal domain 323 428 2.9E-32 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 588 605 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Gene3D G3DSA:3.90.1170.30 618 647 0.32 T 28-03-2018 CNX65_RS08545 89c44095aa8693c894ae9641a07280aa 655 Pfam PF00364 Biotin-requiring enzyme 567 631 1.5E-14 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Gene3D G3DSA:3.40.50.300 288 446 2.6E-12 T 28-03-2018 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Pfam PF13424 Tetratricopeptide repeat 819 887 4.6E-8 T 28-03-2018 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Pfam PF00931 NB-ARC domain 312 497 1.2E-5 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SMART SM00862 52 125 3.9E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Gene3D G3DSA:1.10.10.10 38 133 4.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Pfam PF03704 Bacterial transcriptional activator domain 132 270 6.0E-30 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Gene3D G3DSA:1.25.40.10 743 807 0.0017 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Gene3D G3DSA:1.25.40.10 134 287 1.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SUPERFAMILY SSF48452 754 930 8.35E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 PRINTS PR00364 Disease resistance protein signature 485 499 4.5E-7 T 28-03-2018 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 PRINTS PR00364 Disease resistance protein signature 318 333 4.5E-7 T 28-03-2018 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 PRINTS PR00364 Disease resistance protein signature 397 411 4.5E-7 T 28-03-2018 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SUPERFAMILY SSF46894 39 125 2.21E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SUPERFAMILY SSF52540 291 551 8.3E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Gene3D G3DSA:1.25.40.10 808 944 6.2E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Pfam PF00486 Transcriptional regulatory protein, C terminal 61 125 3.0E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Gene3D G3DSA:1.10.150.200 677 742 4.3E-4 T 28-03-2018 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SMART SM00028 815 848 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SMART SM00028 855 888 0.31 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SMART SM00028 895 928 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SMART SM00028 735 768 27.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SUPERFAMILY SSF48452 127 290 9.1E-24 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 Gene3D G3DSA:1.10.10.10 536 610 2.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17135 9f2e3d0401c7f566584ec27bef167a52 947 SMART SM01043 132 271 1.0E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 Pfam PF07690 Major Facilitator Superfamily 21 239 1.2E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 Pfam PF00083 Sugar (and other) transporter 256 397 2.1E-10 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 PRINTS PR01035 Tetracycline resistance protein signature 282 303 1.8E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 PRINTS PR01035 Tetracycline resistance protein signature 141 163 1.8E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 PRINTS PR01035 Tetracycline resistance protein signature 344 367 1.8E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 PRINTS PR01035 Tetracycline resistance protein signature 26 42 1.8E-8 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 ProSitePatterns PS00216 Sugar transport proteins signature 1. 273 289 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 SUPERFAMILY SSF103473 15 396 3.66E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 Gene3D G3DSA:1.20.1250.20 14 205 3.7E-35 T 28-03-2018 CNX65_RS04705 18441b60d17770c0dde9a8c2c86e8f91 435 Gene3D G3DSA:1.20.1250.20 206 406 1.4E-38 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF00550 Phosphopantetheine attachment site 2129 2193 5.1E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF00550 Phosphopantetheine attachment site 485 548 4.8E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 723 739 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF00698 Acyl transferase domain 1123 1427 1.2E-62 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF08659 KR domain 1864 2034 1.8E-46 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.40.366.10 1117 1256 3.1E-42 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF55048 1245 1307 5.75E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 818 932 1.5E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF14765 Polyketide synthase dehydratase 1464 1718 1.6E-41 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SMART SM00823 Phosphopantetheine attachment site 482 552 8.3E-20 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SMART SM00823 Phosphopantetheine attachment site 2127 2197 2.6E-26 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2152 2167 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.30.70.250 1257 1298 9.8E-13 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 935 989 1.1E-8 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 564 810 6.4E-83 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF13193 AMP-binding enzyme C-terminal domain 394 466 3.7E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.10.129.10 1464 1583 6.5E-11 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.40.50.720 1854 2220 3.5E-59 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1864 2036 9.0E-47 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF47336 2122 2207 1.11E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF47336 483 579 2.88E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SMART SM01294 2128 2193 0.0021 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.30.300.30 380 467 7.7E-24 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF52151 1120 1245 3.4E-56 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF52151 1309 1394 3.4E-56 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.40.366.10 1299 1396 2.2E-20 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.40.50.980 143 293 1.1E-42 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Pfam PF00501 AMP-binding enzyme 17 385 8.9E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF53901 562 929 1.58E-96 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.40.47.10 825 983 2.3E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.40.50.980 8 142 2.0E-32 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SMART SM00825 Beta-ketoacyl synthase 566 985 3.0E-196 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1124 1408 3.2E-87 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF56801 17 478 2.09E-140 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:3.40.47.10 559 822 3.8E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:1.10.1200.10 468 558 6.9E-16 T 28-03-2018 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 ProSitePatterns PS00455 Putative AMP-binding domain signature. 138 149 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF51735 1709 1853 1.34E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SMART SM00826 1464 1621 6.5E-58 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 SUPERFAMILY SSF51735 1864 2101 3.26E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23005 ca984f856ae238392976ede6ef83fd9f 2229 Gene3D G3DSA:2.30.38.10 294 378 6.2E-30 T 28-03-2018 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 SUPERFAMILY SSF52540 255 452 1.78E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 Gene3D G3DSA:3.40.50.300 220 287 1.7E-11 T 28-03-2018 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 PIRSF PIRSF006809 24 479 1.8E-153 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 Pfam PF13167 GTP-binding GTPase N-terminal 72 160 2.8E-33 T 28-03-2018 IPR025121 GTPase HflX, N-terminal CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 Pfam PF01926 50S ribosome-binding GTPase 256 378 4.4E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 56 416 7.2E-129 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 323 341 9.5E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 256 276 9.5E-8 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 Hamap MF_00900 GTPase HflX [hflX]. 75 448 47.158 T 28-03-2018 IPR016496 GTPase HflX GO:0005525 CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 Pfam PF16360 GTP-binding GTPase Middle Region 162 248 4.3E-29 T 28-03-2018 IPR032305 GTP-binding protein, middle domain CNX65_RS07115 eb52d8f338f4b3080d8503f002821dab 480 Gene3D G3DSA:3.40.50.300 288 415 1.4E-15 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:2.60.40.1130 1036 1134 5.6E-11 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Pfam PF11852 Domain of unknown function (DUF3372) 1720 1865 1.6E-31 T 28-03-2018 IPR024561 Alpha-1,6-glucosidases, pullulanase-type, C-terminal CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SUPERFAMILY SSF51445 1240 1780 1.13E-120 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 TIGRFAM TIGR02103 pullul_strch: alpha-1,6-glucosidases, pullulanase-type 1076 1830 3.8E-262 T 28-03-2018 IPR011839 Alpha-1,6-glucosidases, pullulanase-type GO:0005975|GO:0051060 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:2.60.40.1180 556 631 1.0E-10 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:2.60.40.1110 735 841 1.3E-25 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:2.60.40.1110 910 1015 8.2E-24 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SUPERFAMILY SSF49452 747 844 1.54E-28 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 1144 1222 5.1E-11 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SUPERFAMILY SSF49452 909 1015 1.44E-27 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SUPERFAMILY SSF81296 1144 1238 2.3E-15 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:3.20.20.80 64 555 5.1E-81 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:3.20.20.80 1238 1785 2.8E-80 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SMART SM00642 86 541 7.6E-85 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SUPERFAMILY SSF81296 1030 1134 3.22E-13 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:2.60.40.10 1135 1237 2.0E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Gene3D G3DSA:2.60.40.1180 1786 1867 1.1E-12 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Pfam PF00128 Alpha amylase, catalytic domain 124 489 1.2E-71 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SUPERFAMILY SSF51011 1781 1866 5.04E-9 T 28-03-2018 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 SUPERFAMILY SSF51445 84 489 4.08E-83 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Pfam PF03714 Bacterial pullanase-associated domain 924 1015 1.1E-17 T 28-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 CNX65_RS05830 9a9a2a908b67ef7ba5801d5149c7cbfb 1867 Pfam PF03714 Bacterial pullanase-associated domain 750 841 1.7E-21 T 28-03-2018 IPR005323 Pullulanase, carbohydrate-binding module 41 GO:0005975|GO:0030246 CNX65_RS28015 d6b3900a2b1efb234f46515eaa9fccc1 296 SUPERFAMILY SSF52518 4 164 4.76E-32 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS28015 d6b3900a2b1efb234f46515eaa9fccc1 296 Pfam PF02779 Transketolase, pyrimidine binding domain 6 157 2.5E-20 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS28015 d6b3900a2b1efb234f46515eaa9fccc1 296 Gene3D G3DSA:3.40.50.970 37 169 9.8E-29 T 28-03-2018 CNX65_RS28015 d6b3900a2b1efb234f46515eaa9fccc1 296 SMART SM00861 4 160 4.3E-25 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS28015 d6b3900a2b1efb234f46515eaa9fccc1 296 SUPERFAMILY SSF52922 173 293 1.96E-11 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS28015 d6b3900a2b1efb234f46515eaa9fccc1 296 Gene3D G3DSA:3.40.50.920 171 294 1.8E-15 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS28440 c08519a3d1e4f87f30095fead3b0c6b3 151 Pfam PF09056 Prokaryotic phospholipase A2 36 141 3.9E-36 T 28-03-2018 IPR015141 Phospholipase A2, prokaryotic/fungal CNX65_RS28440 c08519a3d1e4f87f30095fead3b0c6b3 151 Gene3D G3DSA:1.20.90.10 38 141 6.3E-22 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CNX65_RS28440 c08519a3d1e4f87f30095fead3b0c6b3 151 SUPERFAMILY SSF48619 34 141 3.55E-27 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 SUPERFAMILY SSF46911 5 76 2.88E-26 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 Gene3D G3DSA:4.10.640.10 1 79 4.2E-31 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 25 76 1.0E-21 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 28-03-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 Pfam PF01084 Ribosomal protein S18 24 72 8.7E-24 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 1.6E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 1.6E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 1.6E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 1.6E-16 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 3 77 20.621 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34790 e1e977e5f6ea3d250cc02bfa1f6d91e9 79 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 76 3.5E-29 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS24915 76a1f52b588a7ec5b63ed5a6f9a00d50 333 Gene3D G3DSA:1.10.3470.10 2 333 4.3E-63 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS24915 76a1f52b588a7ec5b63ed5a6f9a00d50 333 SUPERFAMILY SSF81345 6 327 1.19E-74 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS24915 76a1f52b588a7ec5b63ed5a6f9a00d50 333 Pfam PF01032 FecCD transport family 18 327 1.2E-87 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS25685 910f79f0c92724ecf7d4697b36d3c412 250 Pfam PF02575 YbaB/EbfC DNA-binding family 28 103 1.3E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS25685 910f79f0c92724ecf7d4697b36d3c412 250 SUPERFAMILY SSF82607 29 101 4.45E-5 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS25685 910f79f0c92724ecf7d4697b36d3c412 250 Gene3D G3DSA:3.30.1310.10 1 110 1.5E-19 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS18280 c7d57a8a47f6609c872b632b39a7c51d 741 SUPERFAMILY SSF53187 22 300 3.14E-47 T 28-03-2018 CNX65_RS18280 c7d57a8a47f6609c872b632b39a7c51d 741 Pfam PF04389 Peptidase family M28 106 294 5.6E-36 T 28-03-2018 IPR007484 Peptidase M28 CNX65_RS18280 c7d57a8a47f6609c872b632b39a7c51d 741 Gene3D G3DSA:3.40.630.10 29 306 4.1E-47 T 28-03-2018 CNX65_RS15265 b0565b6ed1b5cc671e4e346c4d211f9d 649 SUPERFAMILY SSF52540 431 612 1.84E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15265 b0565b6ed1b5cc671e4e346c4d211f9d 649 ProSitePatterns PS00211 ABC transporters family signature. 540 554 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS15265 b0565b6ed1b5cc671e4e346c4d211f9d 649 Pfam PF00664 ABC transporter transmembrane region 115 378 5.7E-18 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS15265 b0565b6ed1b5cc671e4e346c4d211f9d 649 Gene3D G3DSA:1.20.1560.10 91 407 1.8E-34 T 28-03-2018 CNX65_RS15265 b0565b6ed1b5cc671e4e346c4d211f9d 649 SUPERFAMILY SSF90123 102 411 2.49E-42 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS15265 b0565b6ed1b5cc671e4e346c4d211f9d 649 Gene3D G3DSA:3.40.50.300 428 647 2.4E-24 T 28-03-2018 CNX65_RS15265 b0565b6ed1b5cc671e4e346c4d211f9d 649 Pfam PF00005 ABC transporter 480 566 7.1E-7 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS32660 375dcd76c7b0c97d2a16c048bde8891b 324 Pfam PF01636 Phosphotransferase enzyme family 66 267 2.8E-18 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS32660 375dcd76c7b0c97d2a16c048bde8891b 324 SUPERFAMILY SSF56112 44 296 8.57E-33 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS32660 375dcd76c7b0c97d2a16c048bde8891b 324 Gene3D G3DSA:3.90.1200.10 127 320 1.9E-18 T 28-03-2018 CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 59 353 3.8E-18 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 ProSitePatterns PS00211 ABC transporters family signature. 804 818 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 Gene3D G3DSA:3.40.50.300 671 938 4.3E-59 T 28-03-2018 CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 Gene3D G3DSA:3.40.50.1820 43 413 6.8E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 Gene3D G3DSA:2.60.120.260 414 637 2.3E-19 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 SUPERFAMILY SSF53474 320 400 9.21E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 SUPERFAMILY SSF53474 58 190 9.21E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 Pfam PF00005 ABC transporter 692 832 3.5E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 SMART SM00382 700 881 1.3E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 SUPERFAMILY SSF49785 470 625 2.34E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 SMART SM00939 391 635 3.6E-6 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 SUPERFAMILY SSF52540 669 894 3.1E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27460 79dd0d275b61eb759ecc1ca4da5a83be 969 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 486 602 2.2E-5 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS26160 9c3d1508bb8f1d629ff757aee1025702 194 Pfam PF01478 Type IV leader peptidase family 60 163 2.6E-14 T 28-03-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 CNX65_RS26160 9c3d1508bb8f1d629ff757aee1025702 194 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 68 85 5.4E-6 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CNX65_RS26160 9c3d1508bb8f1d629ff757aee1025702 194 PRINTS PR00864 Type IV prepilin cysteine protease (C20) family signature 145 160 5.4E-6 T 28-03-2018 IPR014032 Peptidase A24A, prepilin type IV, bacterial CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 SUPERFAMILY SSF53187 339 427 5.74E-55 T 28-03-2018 CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 SUPERFAMILY SSF53187 3 192 5.74E-55 T 28-03-2018 CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 PIRSF PIRSF036696 3 236 2.0E-33 T 28-03-2018 CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 PIRSF PIRSF036696 266 410 3.1E-8 T 28-03-2018 CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 SUPERFAMILY SSF55031 278 319 2.24E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 SUPERFAMILY SSF55031 192 234 2.24E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 Pfam PF07687 Peptidase dimerisation domain 189 319 5.3E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 Pfam PF01546 Peptidase family M20/M25/M40 73 427 2.4E-37 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 Gene3D G3DSA:3.30.70.360 196 331 1.7E-22 T 28-03-2018 CNX65_RS17610 400168d8aa8061428e948437d7f3c885 428 Gene3D G3DSA:3.40.630.10 1 195 1.6E-43 T 28-03-2018 CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 SUPERFAMILY SSF52743 163 392 3.93E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 SUPERFAMILY SSF52743 553 661 3.93E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 PRINTS PR00723 Subtilisin serine protease family (S8) signature 170 189 2.3E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 PRINTS PR00723 Subtilisin serine protease family (S8) signature 239 252 2.3E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 PRINTS PR00723 Subtilisin serine protease family (S8) signature 592 608 2.3E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 Gene3D G3DSA:2.60.40.10 675 774 0.0031 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 Gene3D G3DSA:3.40.50.200 122 661 9.7E-73 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 175 186 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 Pfam PF00082 Subtilase family 170 630 5.3E-44 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 593 603 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS02015 988c11d1d2516e94f0838fa82fe23ab6 1059 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 243 253 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS29895 a277f7aaa6b02941579441cf4692824d 442 SUPERFAMILY SSF56112 116 407 3.67E-15 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS29895 a277f7aaa6b02941579441cf4692824d 442 Gene3D G3DSA:3.90.1200.10 222 423 5.4E-13 T 28-03-2018 CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 Gene3D G3DSA:3.40.50.300 597 832 6.5E-56 T 28-03-2018 CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 SMART SM00382 624 804 1.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 SUPERFAMILY SSF52540 609 818 7.7E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 SUPERFAMILY SSF53474 232 340 7.69E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 SUPERFAMILY SSF53474 22 177 7.69E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 428 525 1.0E-9 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 Pfam PF00005 ABC transporter 616 756 1.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 SMART SM00939 327 551 3.1E-5 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 ProSitePatterns PS00211 ABC transporters family signature. 728 742 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 45 180 5.2E-12 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 Gene3D G3DSA:2.60.120.260 334 559 2.5E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 SUPERFAMILY SSF49785 381 525 3.61E-14 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS18355 a44069a7eaf8061bf8bd83abc5485b11 896 Gene3D G3DSA:3.40.50.1820 15 333 6.4E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03620 02dc379579fb923d17dd7cd8ab2383d8 422 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 13 411 23.698 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS03620 02dc379579fb923d17dd7cd8ab2383d8 422 Pfam PF13742 OB-fold nucleic acid binding domain 21 112 5.0E-14 T 28-03-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 CNX65_RS03620 02dc379579fb923d17dd7cd8ab2383d8 422 Gene3D G3DSA:3.90.226.10 153 248 1.6E-4 T 28-03-2018 CNX65_RS03620 02dc379579fb923d17dd7cd8ab2383d8 422 Gene3D G3DSA:2.40.50.140 22 115 1.2E-4 T 28-03-2018 CNX65_RS03620 02dc379579fb923d17dd7cd8ab2383d8 422 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 21 410 4.9E-109 T 28-03-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS03620 02dc379579fb923d17dd7cd8ab2383d8 422 Pfam PF02601 Exonuclease VII, large subunit 135 357 2.0E-58 T 28-03-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 CNX65_RS20650 75bede2dadae2d80a213667ae1fa854c 154 Gene3D G3DSA:1.10.150.120 75 154 3.9E-29 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CNX65_RS20650 75bede2dadae2d80a213667ae1fa854c 154 SUPERFAMILY SSF47741 73 151 6.41E-31 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CNX65_RS20650 75bede2dadae2d80a213667ae1fa854c 154 SUPERFAMILY SSF54292 6 80 1.31E-20 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS20650 75bede2dadae2d80a213667ae1fa854c 154 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 8 53 3.0E-6 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS20650 75bede2dadae2d80a213667ae1fa854c 154 Pfam PF01799 [2Fe-2S] binding domain 73 145 1.4E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CNX65_RS20650 75bede2dadae2d80a213667ae1fa854c 154 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 40 48 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CNX65_RS20650 75bede2dadae2d80a213667ae1fa854c 154 Gene3D G3DSA:3.10.20.30 2 74 3.8E-21 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 SUPERFAMILY SSF52540 33 219 3.1E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 Pfam PF13177 DNA polymerase III, delta subunit 19 177 1.0E-37 T 28-03-2018 CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 240 364 1.8E-14 T 28-03-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 Gene3D G3DSA:1.10.8.60 168 246 5.6E-8 T 28-03-2018 CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 SUPERFAMILY SSF48019 246 363 7.23E-22 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 Gene3D G3DSA:1.20.272.10 247 367 2.5E-21 T 28-03-2018 CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 Gene3D G3DSA:3.40.50.300 2 167 9.6E-38 T 28-03-2018 CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 4 362 7.4E-109 T 28-03-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 CNX65_RS00925 209638c006527263c4f34de624c0c15f 692 SMART SM00382 36 180 9.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Pfam PF08305 NPCBM/NEW2 domain 1282 1421 7.6E-43 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 582 732 1.4E-24 T 28-03-2018 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SMART SM01038 896 1163 1.2E-64 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SMART SM00560 597 730 3.0E-30 T 28-03-2018 IPR006558 LamG-like jellyroll fold CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Pfam PF00703 Glycosyl hydrolases family 2 219 310 1.0E-9 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SUPERFAMILY SSF49303 219 310 1.32E-17 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SUPERFAMILY SSF51445 312 547 9.01E-63 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Gene3D G3DSA:2.60.120.260 26 217 2.7E-52 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SUPERFAMILY SSF49899 553 734 4.08E-27 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Pfam PF02929 Beta galactosidase small chain 898 1162 1.5E-57 T 28-03-2018 IPR004199 Beta galactosidase small chain/ domain 5 GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SUPERFAMILY SSF49785 33 217 8.87E-54 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Gene3D G3DSA:2.70.98.10 888 1165 2.6E-75 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Pfam PF02836 Glycosyl hydrolases family 2, TIM barrel domain 312 544 7.1E-65 T 28-03-2018 IPR006103 Glycoside hydrolase family 2, catalytic domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-6798695 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 58 217 1.3E-37 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SMART SM00776 1278 1423 4.5E-47 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SUPERFAMILY SSF49785 1283 1421 2.98E-37 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Gene3D G3DSA:3.20.20.80 303 553 7.7E-53 T 28-03-2018 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Gene3D G3DSA:2.60.120.200 554 739 1.2E-26 T 28-03-2018 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 PRINTS PR00132 Glycosyl hydrolase family 2 signature 498 513 5.5E-31 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 PRINTS PR00132 Glycosyl hydrolase family 2 signature 321 335 5.5E-31 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 PRINTS PR00132 Glycosyl hydrolase family 2 signature 352 370 5.5E-31 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 PRINTS PR00132 Glycosyl hydrolase family 2 signature 145 160 5.5E-31 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 PRINTS PR00132 Glycosyl hydrolase family 2 signature 426 441 5.5E-31 T 28-03-2018 IPR006101 Glycoside hydrolase, family 2 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807|Reactome: R-HSA-2024096|Reactome: R-HSA-2160916|Reactome: R-HSA-6798695 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Gene3D G3DSA:2.60.40.10 218 302 4.3E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SUPERFAMILY SSF74650 883 1165 3.77E-60 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 Gene3D G3DSA:2.60.40.10 787 887 6.7E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS23115 491946c1dedc1f44d2aa679f6dbf40fd 1424 SUPERFAMILY SSF49303 785 871 2.81E-8 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 93 318 2.3E-36 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 Gene3D G3DSA:1.10.601.10 5 166 1.6E-68 T 28-03-2018 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 PRINTS PR00046 Major sigma-70 factor signature 269 281 3.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 PRINTS PR00046 Major sigma-70 factor signature 290 305 3.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 PRINTS PR00046 Major sigma-70 factor signature 145 153 3.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 PRINTS PR00046 Major sigma-70 factor signature 121 134 3.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 PRINTS PR00046 Major sigma-70 factor signature 305 316 3.5E-28 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 SUPERFAMILY SSF88946 32 167 2.22E-52 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 SUPERFAMILY SSF88659 170 243 1.96E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 290 316 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 Pfam PF04545 Sigma-70, region 4 265 318 5.1E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 SUPERFAMILY SSF88659 227 322 2.99E-25 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 Pfam PF04542 Sigma-70 region 2 97 166 5.3E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 Pfam PF00140 Sigma-70 factor, region 1.2 32 65 5.6E-14 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 Gene3D G3DSA:1.10.10.10 259 330 5.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 Pfam PF04539 Sigma-70 region 3 176 251 7.0E-26 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 Gene3D G3DSA:1.10.10.10 167 217 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07395 f5a531770ae34a30ce0eb5c98a778cd6 330 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 121 134 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 Gene3D G3DSA:1.10.10.10 5 24 2.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 SMART SM00354 10 81 2.1E-11 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 Pfam PF13377 Periplasmic binding protein-like domain 178 352 6.9E-29 T 28-03-2018 CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 Pfam PF00356 Bacterial regulatory proteins, lacI family 13 54 8.9E-6 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 Gene3D G3DSA:3.40.50.2300 185 333 2.0E-39 T 28-03-2018 CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 Gene3D G3DSA:3.40.50.2300 65 184 6.1E-27 T 28-03-2018 CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 Gene3D G3DSA:1.10.260.40 25 64 2.7E-17 T 28-03-2018 CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 SUPERFAMILY SSF53822 83 347 1.01E-43 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS01775 687b83075052b81aac6fe638b1e17e79 367 SUPERFAMILY SSF47413 10 68 6.56E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 Gene3D G3DSA:1.25.40.10 675 773 1.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 Pfam PF03704 Bacterial transcriptional activator domain 105 206 3.5E-17 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 SUPERFAMILY SSF48452 680 832 1.58E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 Gene3D G3DSA:1.25.40.10 774 918 2.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 SUPERFAMILY SSF46894 2 88 9.64E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 SMART SM00862 16 88 2.8E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 87 3.6E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 SUPERFAMILY SSF48452 94 225 8.72E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 Gene3D G3DSA:1.25.40.10 146 220 2.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 Gene3D G3DSA:1.10.10.10 1 91 8.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 PRINTS PR00364 Disease resistance protein signature 243 258 7.6E-6 T 28-03-2018 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 PRINTS PR00364 Disease resistance protein signature 399 413 7.6E-6 T 28-03-2018 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 PRINTS PR00364 Disease resistance protein signature 309 323 7.6E-6 T 28-03-2018 CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 SMART SM01043 88 209 1.9E-16 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 SUPERFAMILY SSF52540 210 466 7.07E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23845 c6d5734ab903bfd4cd67b03839ec23ce 930 Gene3D G3DSA:3.40.50.300 221 352 2.7E-10 T 28-03-2018 CNX65_RS12375 298b21984a9b791601e83413ab1dbb69 1338 Gene3D G3DSA:3.40.50.300 1 1257 2.4E-23 T 28-03-2018 CNX65_RS12375 298b21984a9b791601e83413ab1dbb69 1338 SUPERFAMILY SSF52540 1119 1251 7.11E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12375 298b21984a9b791601e83413ab1dbb69 1338 SUPERFAMILY SSF52540 128 233 7.11E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12375 298b21984a9b791601e83413ab1dbb69 1338 SUPERFAMILY SSF52540 1 84 7.11E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12375 298b21984a9b791601e83413ab1dbb69 1338 Pfam PF13514 AAA domain 1 192 2.4E-42 T 28-03-2018 CNX65_RS12375 298b21984a9b791601e83413ab1dbb69 1338 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1310 1337 0.001 T 28-03-2018 IPR024412 Lsr2 CNX65_RS12375 298b21984a9b791601e83413ab1dbb69 1338 Pfam PF11774 Lsr2 1289 1336 1.2E-9 T 28-03-2018 IPR024412 Lsr2 CNX65_RS19370 19807b691968a1ba9f601358c39b22a9 422 Gene3D G3DSA:3.20.20.80 55 322 9.2E-57 T 28-03-2018 CNX65_RS19370 19807b691968a1ba9f601358c39b22a9 422 SUPERFAMILY SSF51445 56 331 1.51E-47 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS19370 19807b691968a1ba9f601358c39b22a9 422 Gene3D G3DSA:2.60.40.1180 323 422 1.3E-22 T 28-03-2018 CNX65_RS19370 19807b691968a1ba9f601358c39b22a9 422 SUPERFAMILY SSF51011 327 421 7.29E-15 T 28-03-2018 CNX65_RS27720 8d7173fa15c64eeebb89d8bcd23415e2 421 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 8 419 50.356 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CNX65_RS27720 8d7173fa15c64eeebb89d8bcd23415e2 421 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 223 239 - T 28-03-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CNX65_RS27720 8d7173fa15c64eeebb89d8bcd23415e2 421 PIRSF PIRSF000412 1 417 1.7E-159 T 28-03-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0006545|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 CNX65_RS27720 8d7173fa15c64eeebb89d8bcd23415e2 421 Gene3D G3DSA:3.90.1150.10 276 418 5.5E-53 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS27720 8d7173fa15c64eeebb89d8bcd23415e2 421 SUPERFAMILY SSF53383 3 419 1.65E-172 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS27720 8d7173fa15c64eeebb89d8bcd23415e2 421 Gene3D G3DSA:3.40.640.10 38 275 1.7E-56 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS27720 8d7173fa15c64eeebb89d8bcd23415e2 421 Pfam PF00464 Serine hydroxymethyltransferase 9 391 2.1E-163 T 28-03-2018 CNX65_RS25260 f3818e95bd5c17bfaf9c2dd5858c360e 184 Gene3D G3DSA:2.60.130.10 1 184 4.2E-54 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS25260 f3818e95bd5c17bfaf9c2dd5858c360e 184 TIGRFAM TIGR02423 protocat_alph: protocatechuate 3,4-dioxygenase, alpha subunit 4 184 6.9E-61 T 28-03-2018 IPR012786 Protocatechuate 3,4-dioxygenase, alpha subunit GO:0005506|GO:0018578|GO:0019439|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CNX65_RS25260 f3818e95bd5c17bfaf9c2dd5858c360e 184 SUPERFAMILY SSF49482 2 183 9.68E-52 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS25260 f3818e95bd5c17bfaf9c2dd5858c360e 184 Pfam PF00775 Dioxygenase 34 162 2.1E-15 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CNX65_RS07370 92d2a5b9a3c7672fb5f8905f18de6c03 418 SUPERFAMILY SSF54826 1 133 4.77E-26 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS07370 92d2a5b9a3c7672fb5f8905f18de6c03 418 Gene3D G3DSA:3.30.390.10 1 140 2.1E-35 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS07370 92d2a5b9a3c7672fb5f8905f18de6c03 418 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 32 133 1.8E-5 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CNX65_RS07370 92d2a5b9a3c7672fb5f8905f18de6c03 418 Gene3D G3DSA:3.20.20.120 141 389 3.6E-55 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS07370 92d2a5b9a3c7672fb5f8905f18de6c03 418 SUPERFAMILY SSF51604 133 385 1.57E-70 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS07370 92d2a5b9a3c7672fb5f8905f18de6c03 418 SMART SM00922 167 261 6.2E-19 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CNX65_RS07370 92d2a5b9a3c7672fb5f8905f18de6c03 418 Pfam PF13378 Enolase C-terminal domain-like 171 381 6.2E-54 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 3 14 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 Pfam PF00871 Acetokinase family 48 350 4.4E-104 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 Hamap MF_00020 Acetate kinase [ackA]. 1 357 137.407 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 Gene3D G3DSA:3.30.420.40 162 357 2.6E-68 T 28-03-2018 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 Gene3D G3DSA:3.30.420.40 41 159 1.3E-49 T 28-03-2018 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 Gene3D G3DSA:3.30.420.40 2 40 0.0014 T 28-03-2018 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 TIGRFAM TIGR00016 ackA: acetate kinase 48 352 1.8E-100 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 SUPERFAMILY SSF53067 121 355 3.61E-72 T 28-03-2018 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 165 182 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 PIRSF PIRSF000722 1 39 0.0021 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 PIRSF PIRSF000722 37 357 1.2E-111 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 SUPERFAMILY SSF53067 1 159 5.5E-53 T 28-03-2018 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 PRINTS PR00471 Acetate kinase family signature 3 14 5.2E-26 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 PRINTS PR00471 Acetate kinase family signature 165 186 5.2E-26 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 PRINTS PR00471 Acetate kinase family signature 338 350 5.2E-26 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 PRINTS PR00471 Acetate kinase family signature 284 300 5.2E-26 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS09585 cb910cb24b90186efd6d77d5f29f966a 357 PRINTS PR00471 Acetate kinase family signature 262 275 5.2E-26 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS21735 1c6437b329456ff5ce75c6d2a86e519d 395 Pfam PF07690 Major Facilitator Superfamily 30 347 1.6E-24 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS21735 1c6437b329456ff5ce75c6d2a86e519d 395 Gene3D G3DSA:1.20.1250.20 199 386 8.0E-18 T 28-03-2018 CNX65_RS21735 1c6437b329456ff5ce75c6d2a86e519d 395 SUPERFAMILY SSF103473 9 392 2.49E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS21735 1c6437b329456ff5ce75c6d2a86e519d 395 Gene3D G3DSA:1.20.1250.20 9 195 2.2E-18 T 28-03-2018 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 Gene3D G3DSA:3.20.20.80 41 422 1.9E-59 T 28-03-2018 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 Gene3D G3DSA:2.60.40.10 459 548 1.2E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 204 213 - T 28-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 Gene3D G3DSA:2.60.40.290 549 651 1.6E-21 T 28-03-2018 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 SMART SM00060 464 537 2.6E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 SUPERFAMILY SSF49265 462 547 1.64E-15 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 SMART SM00637 559 645 3.2E-21 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 Pfam PF00553 Cellulose binding domain 559 647 6.7E-16 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 56 395 6.3E-58 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 SUPERFAMILY SSF51445 45 424 2.86E-76 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS16390 3d0c47fdd9fa56f4ea1950d63cd1417e 651 SUPERFAMILY SSF49384 555 649 7.67E-19 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 4 135 6.1E-24 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 SUPERFAMILY SSF55347 146 308 6.76E-47 T 28-03-2018 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 3 334 37.9 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 3 340 9.8E-114 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 SMART SM00859 4 136 5.4E-42 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 Gene3D G3DSA:3.40.50.720 1 152 1.7E-43 T 28-03-2018 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 SUPERFAMILY SSF51735 3 169 5.06E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 Gene3D G3DSA:3.30.360.10 153 308 7.9E-54 T 28-03-2018 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 141 157 - T 28-03-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS27185 e4fdcc294ac1459a617bef9c0cc468cb 340 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 311 1.1E-24 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Gene3D G3DSA:3.90.1140.10 386 546 4.5E-28 T 28-03-2018 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Pfam PF04928 Poly(A) polymerase central domain 676 757 4.1E-5 T 28-03-2018 IPR007012 Poly(A) polymerase, central domain GO:0004652|GO:0043631 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 SUPERFAMILY SSF56219 116 358 7.33E-34 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 SUPERFAMILY SSF81301 574 654 8.41E-9 T 28-03-2018 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Pfam PF01909 Nucleotidyltransferase domain 566 604 1.7E-5 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 SUPERFAMILY SSF55144 391 544 9.07E-18 T 28-03-2018 IPR009097 Cyclic phosphodiesterase CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Gene3D G3DSA:1.10.1410.10 662 808 5.8E-11 T 28-03-2018 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 120 351 4.8E-16 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Gene3D G3DSA:3.60.10.10 109 359 1.5E-34 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 SUPERFAMILY SSF81631 687 800 8.63E-16 T 28-03-2018 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Gene3D G3DSA:3.30.460.10 555 659 7.0E-8 T 28-03-2018 CNX65_RS15395 eb2e362491a55c59740ee62ae2cc53ad 895 Pfam PF13563 2'-5' RNA ligase superfamily 394 528 5.6E-24 T 28-03-2018 CNX65_RS02815 172ec469d409364e3634c48176b46047 125 SUPERFAMILY SSF46785 3 109 1.39E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02815 172ec469d409364e3634c48176b46047 125 Pfam PF01638 HxlR-like helix-turn-helix 23 107 2.9E-26 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS02815 172ec469d409364e3634c48176b46047 125 Gene3D G3DSA:1.10.10.10 1 120 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Gene3D G3DSA:3.40.50.300 118 184 1.8E-5 T 28-03-2018 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 SMART SM00322 11 74 0.0094 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Pfam PF02562 PhoH-like protein 118 233 3.9E-49 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Pfam PF02562 PhoH-like protein 587 681 5.9E-35 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 SUPERFAMILY SSF52540 587 644 1.5E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Gene3D G3DSA:3.30.1370.10 3 90 8.2E-4 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 SUPERFAMILY SSF52540 117 232 1.16E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Gene3D G3DSA:3.40.50.300 540 636 4.7E-4 T 28-03-2018 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 SUPERFAMILY SSF55608 434 510 7.94E-12 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 SUPERFAMILY SSF51294 237 362 4.04E-16 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 SUPERFAMILY SSF51294 525 592 4.04E-16 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Gene3D G3DSA:3.10.28.10 438 538 6.5E-11 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 SMART SM00306 231 330 0.0073 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Gene3D G3DSA:2.170.16.10 234 338 1.4E-13 T 28-03-2018 CNX65_RS06225 4cf55708cfa00fe869ae619f331f7e7d 709 Gene3D G3DSA:3.10.28.10 339 407 0.099 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CNX65_RS22015 b79a5ec222ac3a5e72ce576b5ac4e80c 229 SUPERFAMILY SSF52317 2 224 3.88E-74 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS22015 b79a5ec222ac3a5e72ce576b5ac4e80c 229 Pfam PF01965 DJ-1/PfpI family 25 213 1.3E-13 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS22015 b79a5ec222ac3a5e72ce576b5ac4e80c 229 Gene3D G3DSA:3.40.50.880 1 227 7.2E-63 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS18855 46b06fdf8dab28d6820bab983cef4d5b 631 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 75 98 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS18855 46b06fdf8dab28d6820bab983cef4d5b 631 Gene3D G3DSA:1.10.510.10 137 340 2.0E-48 T 28-03-2018 CNX65_RS18855 46b06fdf8dab28d6820bab983cef4d5b 631 Pfam PF00069 Protein kinase domain 69 317 2.6E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS18855 46b06fdf8dab28d6820bab983cef4d5b 631 SMART SM00220 69 320 6.9E-66 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS18855 46b06fdf8dab28d6820bab983cef4d5b 631 Gene3D G3DSA:3.30.200.20 58 136 3.1E-23 T 28-03-2018 CNX65_RS18855 46b06fdf8dab28d6820bab983cef4d5b 631 SUPERFAMILY SSF56112 55 332 1.48E-73 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS18855 46b06fdf8dab28d6820bab983cef4d5b 631 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 188 200 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS32825 3c915c6675e45a21db4dd72bcd51dead 258 Gene3D G3DSA:3.75.10.10 1 256 1.2E-60 T 28-03-2018 CNX65_RS32825 3c915c6675e45a21db4dd72bcd51dead 258 Pfam PF02274 Amidinotransferase 53 256 6.3E-12 T 28-03-2018 CNX65_RS32825 3c915c6675e45a21db4dd72bcd51dead 258 SUPERFAMILY SSF55909 1 257 4.71E-55 T 28-03-2018 CNX65_RS32445 6d83c96cd2b02e5b74c2dbdf4553763c 231 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 10 209 32.186 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32445 6d83c96cd2b02e5b74c2dbdf4553763c 231 Pfam PF00573 Ribosomal protein L4/L1 family 18 203 8.6E-61 T 28-03-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 CNX65_RS32445 6d83c96cd2b02e5b74c2dbdf4553763c 231 SUPERFAMILY SSF52166 4 205 1.7E-71 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CNX65_RS32445 6d83c96cd2b02e5b74c2dbdf4553763c 231 Gene3D G3DSA:3.40.1370.10 153 205 1.0E-8 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CNX65_RS32445 6d83c96cd2b02e5b74c2dbdf4553763c 231 Gene3D G3DSA:3.40.1370.10 3 152 5.3E-52 T 28-03-2018 IPR023574 Ribosomal protein L4 domain GO:0003735|GO:0005840|GO:0006412 CNX65_RS32445 6d83c96cd2b02e5b74c2dbdf4553763c 231 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 18 203 7.9E-68 T 28-03-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 Gene3D G3DSA:1.10.8.50 118 261 1.7E-43 T 28-03-2018 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 SMART SM00898 2 105 8.8E-14 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 123 198 2.4E-10 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 SUPERFAMILY SSF57716 219 261 4.56E-8 T 28-03-2018 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 ProSitePatterns PS01242 Zinc finger FPG-type signature. 232 260 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 SMART SM01232 123 213 2.8E-20 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 SUPERFAMILY SSF46946 122 196 5.0E-16 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 SUPERFAMILY SSF81624 2 124 7.29E-23 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 103 8.9E-8 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS28375 e073d29e109067e05099bc848d4895ef 265 Gene3D G3DSA:3.20.190.10 1 117 1.3E-23 T 28-03-2018 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 SMART SM00421 773 830 8.1E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 Gene3D G3DSA:1.10.10.10 786 830 3.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09835 632736200b5234a28799147e74f2f329 831 Gene3D G3DSA:1.25.40.10 259 587 1.2E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 Gene3D G3DSA:1.25.40.10 588 785 2.9E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 SUPERFAMILY SSF46894 770 829 2.62E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 Gene3D G3DSA:3.40.50.300 5 69 6.2E-5 T 28-03-2018 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 SUPERFAMILY SSF52540 10 147 2.93E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09835 632736200b5234a28799147e74f2f329 831 Pfam PF00196 Bacterial regulatory proteins, luxR family 775 828 1.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 ProSitePatterns PS00622 LuxR-type HTH domain signature. 790 817 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 776 790 1.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 806 818 1.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09835 632736200b5234a28799147e74f2f329 831 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 790 806 1.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 SUPERFAMILY SSF48452 802 946 9.7E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:3.40.50.10140 53 191 1.4E-8 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:1.20.1250.10 969 1057 3.9E-7 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:1.20.1250.10 885 968 1.4E-6 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:1.20.1250.10 1312 1380 1.5E-6 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:1.20.1250.10 1231 1311 6.6E-10 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:1.20.1250.10 1058 1152 1.9E-6 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 SMART SM00028 849 882 66.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 SMART SM00028 1074 1107 56.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 SMART SM00028 1257 1290 58.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 SMART SM00028 1303 1336 180.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Pfam PF13676 TIR domain 54 163 3.3E-11 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:1.25.40.10 723 884 1.6E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Gene3D G3DSA:3.40.50.300 228 441 2.1E-4 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Pfam PF13374 Tetratricopeptide repeat 1256 1291 2.0E-5 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 Pfam PF13374 Tetratricopeptide repeat 1302 1339 3.1E-4 T 28-03-2018 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 SUPERFAMILY SSF48452 1247 1332 1.47E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14545 c0b07a78e2fc64ae6284f929f925d942 1402 SUPERFAMILY SSF48452 1033 1144 1.47E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30850 bf86a27d6ad2966183b76103a8d979f7 503 Gene3D G3DSA:1.10.275.10 2 198 1.1E-70 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CNX65_RS30850 bf86a27d6ad2966183b76103a8d979f7 503 SUPERFAMILY SSF48557 3 499 2.9E-180 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CNX65_RS30850 bf86a27d6ad2966183b76103a8d979f7 503 Pfam PF00221 Aromatic amino acid lyase 11 473 4.7E-181 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CNX65_RS30850 bf86a27d6ad2966183b76103a8d979f7 503 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 139 155 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CNX65_RS30850 bf86a27d6ad2966183b76103a8d979f7 503 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 4 498 7.9E-197 T 28-03-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30850 bf86a27d6ad2966183b76103a8d979f7 503 Gene3D G3DSA:1.20.200.10 200 501 2.6E-119 T 28-03-2018 CNX65_RS17805 bbd2d82bbb617a5ec8a1fb8c03d3788d 105 SUPERFAMILY SSF46785 7 96 2.58E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17805 bbd2d82bbb617a5ec8a1fb8c03d3788d 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 2.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17805 bbd2d82bbb617a5ec8a1fb8c03d3788d 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 25 40 2.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17805 bbd2d82bbb617a5ec8a1fb8c03d3788d 105 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 71 86 2.0E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS17805 bbd2d82bbb617a5ec8a1fb8c03d3788d 105 Pfam PF12840 Helix-turn-helix domain 24 79 2.7E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17805 bbd2d82bbb617a5ec8a1fb8c03d3788d 105 Gene3D G3DSA:1.10.10.10 2 93 1.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17805 bbd2d82bbb617a5ec8a1fb8c03d3788d 105 SMART SM00418 23 103 3.4E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 PRINTS PR00783 Major intrinsic protein family signature 224 244 2.2E-34 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 PRINTS PR00783 Major intrinsic protein family signature 177 199 2.2E-34 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 PRINTS PR00783 Major intrinsic protein family signature 83 102 2.2E-34 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 PRINTS PR00783 Major intrinsic protein family signature 46 70 2.2E-34 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 PRINTS PR00783 Major intrinsic protein family signature 5 24 2.2E-34 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 PRINTS PR00783 Major intrinsic protein family signature 138 156 2.2E-34 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 Gene3D G3DSA:1.20.1080.10 2 245 3.4E-76 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 Pfam PF00230 Major intrinsic protein 7 241 4.4E-38 T 28-03-2018 IPR000425 Major intrinsic protein GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 ProSitePatterns PS00221 MIP family signature. 64 72 - T 28-03-2018 IPR022357 Major intrinsic protein, conserved site GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-432047 CNX65_RS31460 3bda275f12553550243e290c4e6904d5 246 SUPERFAMILY SSF81338 7 243 2.09E-59 T 28-03-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 CNX65_RS04350 5ff380e8a456ec4e0f7e1ec49cd17130 182 SUPERFAMILY SSF52218 4 145 1.19E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS04350 5ff380e8a456ec4e0f7e1ec49cd17130 182 Gene3D G3DSA:3.40.50.360 2 180 1.6E-26 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS04350 5ff380e8a456ec4e0f7e1ec49cd17130 182 Pfam PF03358 NADPH-dependent FMN reductase 3 143 4.6E-24 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 182 1.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 198 210 1.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 198 1.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 Gene3D G3DSA:3.40.50.2300 23 142 7.4E-10 T 28-03-2018 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 SMART SM00421 165 222 1.6E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 SUPERFAMILY SSF52172 22 144 1.1E-8 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 SUPERFAMILY SSF46894 164 228 2.82E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 ProSitePatterns PS00622 LuxR-type HTH domain signature. 182 209 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 Pfam PF00196 Bacterial regulatory proteins, luxR family 167 222 1.3E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34405 bfecec99b5d1ecf3651f708d06654eeb 234 Gene3D G3DSA:1.10.10.10 143 231 5.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 417 446 1.8E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 36 61 1.8E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 388 415 1.8E-18 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 Pfam PF00672 HAMP domain 230 278 2.2E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 Gene3D G3DSA:1.10.287.950 353 545 1.1E-46 T 28-03-2018 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 Gene3D G3DSA:1.20.120.30 44 186 2.6E-7 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 SMART SM00304 415 478 59.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 SMART SM00304 230 282 1.8E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 SMART SM00283 290 544 4.3E-53 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 Gene3D G3DSA:1.10.287.950 233 352 7.6E-8 T 28-03-2018 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 Pfam PF12729 Four helix bundle sensory module for signal transduction 27 187 1.4E-8 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 349 527 7.5E-32 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS11815 fce3f4c1b3b571ac9bb84c90aca8fb60 545 SUPERFAMILY SSF58104 250 544 1.02E-65 T 28-03-2018 CNX65_RS23190 c718b460566993d458d072aacfda170f 404 Gene3D G3DSA:3.40.50.20 1 107 3.0E-14 T 28-03-2018 CNX65_RS23190 c718b460566993d458d072aacfda170f 404 SUPERFAMILY SSF56059 93 316 1.06E-38 T 28-03-2018 CNX65_RS23190 c718b460566993d458d072aacfda170f 404 SMART SM01209 103 282 0.0019 T 28-03-2018 CNX65_RS23190 c718b460566993d458d072aacfda170f 404 Pfam PF13535 ATP-grasp domain 139 284 1.3E-16 T 28-03-2018 CNX65_RS23190 c718b460566993d458d072aacfda170f 404 Gene3D G3DSA:3.30.470.20 108 394 1.7E-46 T 28-03-2018 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Gene3D G3DSA:3.30.365.10 588 728 8.5E-29 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 SUPERFAMILY SSF56003 356 725 5.58E-81 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Gene3D G3DSA:3.30.365.10 69 231 2.0E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Gene3D G3DSA:3.30.365.10 352 443 1.6E-20 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 PIRSF PIRSF036389 50 728 7.2E-180 T 28-03-2018 IPR012368 Oxidoreductase molybdopterin-binding subunit, IorB-related CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 598 679 8.4E-10 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 358 564 3.9E-14 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 48 213 2.3E-16 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 SUPERFAMILY SSF56003 37 280 1.5E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 SMART SM01008 246 330 2.0E-12 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Gene3D G3DSA:3.90.1170.50 232 348 1.1E-21 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CNX65_RS20645 6960f8c95c06e8240dc51b32c4760517 729 Gene3D G3DSA:3.30.365.10 444 587 5.4E-25 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 Pfam PF01037 Lrp/AsnC ligand binding domain 68 139 1.1E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 Gene3D G3DSA:1.10.10.10 1 50 6.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 SUPERFAMILY SSF54909 62 148 6.44E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 2.0E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 2.0E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 2.0E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 SUPERFAMILY SSF46785 1 60 5.97E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 Pfam PF13404 AsnC-type helix-turn-helix domain 2 42 5.6E-13 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 Gene3D G3DSA:3.30.70.920 54 151 8.9E-15 T 28-03-2018 CNX65_RS12865 870b5421fc2c564d686d95eb24c32325 155 SMART SM00344 1 110 1.2E-16 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 292 299 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Gene3D G3DSA:3.90.226.10 1262 1503 1.3E-12 T 28-03-2018 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Gene3D G3DSA:3.30.1490.20 129 214 7.0E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Pfam PF08326 Acetyl-CoA carboxylase, central region 1047 1207 4.2E-17 T 28-03-2018 IPR013537 Acetyl-CoA carboxylase, central domain GO:0003989|GO:0005524|GO:0006633 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-163765|Reactome: R-HSA-196780|Reactome: R-HSA-200425|Reactome: R-HSA-2426168 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Pfam PF02785 Biotin carboxylase C-terminal domain 340 449 2.4E-35 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 SUPERFAMILY SSF52096 1293 1499 3.91E-22 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 SUPERFAMILY SSF51230 582 655 1.3E-15 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 328 4.8E-62 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Pfam PF01039 Carboxyl transferase domain 1332 1821 2.5E-32 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 SUPERFAMILY SSF51246 335 450 6.8E-36 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Gene3D G3DSA:2.40.50.100 640 689 2.6E-4 T 28-03-2018 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Pfam PF00289 Biotin carboxylase, N-terminal domain 2 115 9.1E-33 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Gene3D G3DSA:3.40.50.20 1 128 3.0E-38 T 28-03-2018 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Gene3D G3DSA:3.30.470.20 215 450 4.3E-87 T 28-03-2018 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Gene3D G3DSA:2.40.50.100 582 639 6.6E-14 T 28-03-2018 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 SUPERFAMILY SSF56059 88 335 5.13E-59 T 28-03-2018 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Pfam PF00364 Biotin-requiring enzyme 589 654 3.0E-9 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 SUPERFAMILY SSF52440 2 118 5.56E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 Gene3D G3DSA:3.90.226.10 1512 1827 2.7E-40 T 28-03-2018 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 SMART SM00878 340 448 3.7E-51 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS21235 905cb2966b65564570131655f3e614e7 1827 SUPERFAMILY SSF52096 1515 1825 1.26E-38 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS20825 59cac096891e876af372caa320eda2bc 503 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 441 1.3E-129 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Pfam PF07676 WD40-like Beta Propeller Repeat 58 79 0.0084 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Pfam PF07676 WD40-like Beta Propeller Repeat 464 494 0.035 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Gene3D G3DSA:3.30.750.44 677 744 3.3E-20 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SUPERFAMILY SSF50156 754 843 3.28E-17 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Gene3D G3DSA:3.90.226.10 850 1061 1.4E-30 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 PIRSF PIRSF036421 5 1062 0.0 T 28-03-2018 IPR012393 Tricorn protease GO:0008236 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Pfam PF14685 Tricorn protease PDZ domain 754 843 6.0E-30 T 28-03-2018 IPR029414 Tricorn protease, PDZ domain CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SUPERFAMILY SSF69304 20 277 3.27E-34 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Gene3D G3DSA:2.120.10.60 12 280 5.6E-31 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Pfam PF14684 Tricorn protease C1 domain 677 743 4.2E-27 T 28-03-2018 IPR028204 Tricorn protease C1 domain CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Gene3D G3DSA:2.30.42.10 752 849 9.9E-11 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SMART SM00245 823 1029 1.0E-22 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SUPERFAMILY SSF52096 674 753 2.32E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SUPERFAMILY SSF52096 845 1055 2.32E-65 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SUPERFAMILY SSF69322 623 644 1.57E-25 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SUPERFAMILY SSF69322 247 301 1.57E-25 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 SUPERFAMILY SSF69322 345 522 1.57E-25 T 28-03-2018 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Pfam PF03572 Peptidase family S41 872 1028 1.4E-19 T 28-03-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 CNX65_RS03315 5dcc01b46b3bc7f989886e7d8c7efa2e 1069 Gene3D G3DSA:2.130.10.10 300 664 1.7E-59 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS04430 0ab07ec3e37fa0bfb86f51a60bd4944d 287 SUPERFAMILY SSF51621 25 285 2.08E-99 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS04430 0ab07ec3e37fa0bfb86f51a60bd4944d 287 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 25 287 2.3E-82 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CNX65_RS04430 0ab07ec3e37fa0bfb86f51a60bd4944d 287 Gene3D G3DSA:3.20.20.60 18 286 2.0E-82 T 28-03-2018 CNX65_RS04430 0ab07ec3e37fa0bfb86f51a60bd4944d 287 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 26 286 40.394 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CNX65_RS04430 0ab07ec3e37fa0bfb86f51a60bd4944d 287 Pfam PF02548 Ketopantoate hydroxymethyltransferase 25 281 1.8E-104 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CNX65_RS04430 0ab07ec3e37fa0bfb86f51a60bd4944d 287 PIRSF PIRSF000388 18 287 2.0E-105 T 28-03-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 CNX65_RS29975 81d69d137e592720c66e16dadedc208b 344 Pfam PF02653 Branched-chain amino acid transport system / permease component 57 331 6.3E-36 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS29975 81d69d137e592720c66e16dadedc208b 344 Gene3D G3DSA:1.10.3470.10 22 339 2.7E-19 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 SUPERFAMILY SSF51445 40 336 1.66E-72 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 Pfam PF00041 Fibronectin type III domain 349 424 7.0E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 Gene3D G3DSA:2.60.40.290 434 544 3.3E-32 T 28-03-2018 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 SMART SM00637 444 544 5.1E-39 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 49 295 4.6E-32 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 SUPERFAMILY SSF49384 442 544 6.98E-30 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 SUPERFAMILY SSF49265 345 447 1.53E-14 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 Gene3D G3DSA:2.60.40.10 340 433 2.3E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 Gene3D G3DSA:3.20.20.80 23 337 2.4E-48 T 28-03-2018 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 Pfam PF00553 Cellulose binding domain 444 544 1.4E-27 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS09130 403c8acd6638760bd2523d6fba8e911c 547 SMART SM00060 347 424 1.0E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 245 282 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 Gene3D G3DSA:3.90.1150.10 2 166 2.1E-37 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 Gene3D G3DSA:3.40.640.10 198 318 1.2E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 Gene3D G3DSA:3.90.1150.10 319 438 1.1E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 Pfam PF00202 Aminotransferase class-III 32 434 9.4E-89 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 SUPERFAMILY SSF53383 11 436 3.32E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 PIRSF PIRSF000521 14 140 1.4E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS23965 ea6bd46fbedd3d9e072812435c70cb07 443 PIRSF PIRSF000521 127 437 3.3E-28 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Gene3D G3DSA:3.30.420.10 328 501 1.0E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Gene3D G3DSA:3.30.70.370 615 711 1.5E-16 T 28-03-2018 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Gene3D G3DSA:3.30.70.370 713 888 1.2E-46 T 28-03-2018 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SUPERFAMILY SSF56672 482 886 1.07E-137 T 28-03-2018 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 659 682 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 689 702 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 750 761 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 713 738 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 834 847 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 613 635 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 636 651 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 772 783 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 PRINTS PR00868 DNA-polymerase family A (pol I) signature 804 820 2.8E-75 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 ProSitePatterns PS00447 DNA polymerase family A signature. 713 732 - T 28-03-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 177 271 2.1E-22 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Pfam PF00476 DNA polymerase family A 509 885 2.0E-144 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SUPERFAMILY SSF47807 177 290 8.67E-26 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SMART SM00279 179 214 4.2E-7 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SMART SM00474 308 477 3.7E-6 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Gene3D G3DSA:3.40.50.1010 7 189 4.1E-67 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Gene3D G3DSA:1.10.150.20 190 268 5.6E-21 T 28-03-2018 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 8 175 5.7E-54 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SUPERFAMILY SSF88723 8 159 1.93E-52 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SUPERFAMILY SSF53098 335 477 2.73E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 TIGRFAM TIGR00593 pola: DNA polymerase I 9 886 4.9E-296 T 28-03-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SMART SM00482 644 851 3.7E-110 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 SMART SM00475 7 267 1.5E-126 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CNX65_RS27545 e7f2c6795d1f3ed758f7beafee342061 888 Gene3D G3DSA:1.20.1060.10 502 614 7.1E-26 T 28-03-2018 CNX65_RS22835 549e6e2175635ef045b9b923455ab2d8 357 SUPERFAMILY SSF50129 165 174 1.1E-25 T 28-03-2018 IPR011032 GroES-like CNX65_RS22835 549e6e2175635ef045b9b923455ab2d8 357 SUPERFAMILY SSF50129 2 136 1.1E-25 T 28-03-2018 IPR011032 GroES-like CNX65_RS22835 549e6e2175635ef045b9b923455ab2d8 357 SMART SM00829 5 352 8.9E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS22835 549e6e2175635ef045b9b923455ab2d8 357 Gene3D G3DSA:3.40.50.720 160 341 2.4E-19 T 28-03-2018 CNX65_RS22835 549e6e2175635ef045b9b923455ab2d8 357 SUPERFAMILY SSF51735 148 322 4.91E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22835 549e6e2175635ef045b9b923455ab2d8 357 Gene3D G3DSA:3.90.180.10 1 159 3.3E-26 T 28-03-2018 CNX65_RS22835 549e6e2175635ef045b9b923455ab2d8 357 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 21 130 1.3E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 PRINTS PR00133 Glycosyl hydrolase family 3 signature 66 85 7.5E-32 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 PRINTS PR00133 Glycosyl hydrolase family 3 signature 143 159 7.5E-32 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 PRINTS PR00133 Glycosyl hydrolase family 3 signature 213 231 7.5E-32 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 PRINTS PR00133 Glycosyl hydrolase family 3 signature 112 128 7.5E-32 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 PRINTS PR00133 Glycosyl hydrolase family 3 signature 30 46 7.5E-32 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 Gene3D G3DSA:3.20.20.300 7 303 1.3E-96 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 Gene3D G3DSA:2.60.40.10 543 659 2.0E-39 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 Pfam PF14310 Fibronectin type III-like domain 575 645 5.1E-24 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 Gene3D G3DSA:3.40.50.1700 304 542 7.6E-73 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 SUPERFAMILY SSF51445 31 309 7.05E-85 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 311 542 1.4E-48 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 SMART SM01217 575 645 8.6E-30 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 31 279 1.2E-51 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24090 5dcdeebbb36b26c6a3aabddde94d2bf4 742 SUPERFAMILY SSF52279 311 545 1.83E-46 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS34765 52f3ee89945ab77eb498c93b9735e856 465 PIRSF PIRSF010361 6 464 5.8E-71 T 28-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane CNX65_RS34765 52f3ee89945ab77eb498c93b9735e856 465 Pfam PF05007 Mannosyltransferase (PIG-M) 206 375 6.1E-7 T 28-03-2018 IPR007704 Mannosyltransferase, DXD GO:0006506|GO:0016021|GO:0016758 Reactome: R-HSA-162710 CNX65_RS04650 df18a4761814f943842cf3b534009bc7 229 Pfam PF00005 ABC transporter 19 166 1.5E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS04650 df18a4761814f943842cf3b534009bc7 229 Gene3D G3DSA:3.40.50.300 1 223 4.6E-66 T 28-03-2018 CNX65_RS04650 df18a4761814f943842cf3b534009bc7 229 SUPERFAMILY SSF52540 1 221 5.47E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04650 df18a4761814f943842cf3b534009bc7 229 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 8.5E-86 T 28-03-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 CNX65_RS04650 df18a4761814f943842cf3b534009bc7 229 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS04650 df18a4761814f943842cf3b534009bc7 229 SMART SM00382 28 215 3.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03275 3bf07419a7af49ff2fe95ebf89274674 329 Pfam PF00487 Fatty acid desaturase 59 277 1.1E-18 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CNX65_RS03275 3bf07419a7af49ff2fe95ebf89274674 329 PRINTS PR00075 Fatty acid desaturase family 1 signature 81 101 3.5E-7 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CNX65_RS03275 3bf07419a7af49ff2fe95ebf89274674 329 PRINTS PR00075 Fatty acid desaturase family 1 signature 118 147 3.5E-7 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CNX65_RS03275 3bf07419a7af49ff2fe95ebf89274674 329 PRINTS PR00075 Fatty acid desaturase family 1 signature 58 80 3.5E-7 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 SUPERFAMILY SSF55021 251 331 5.07E-19 T 28-03-2018 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 64 406 2.4E-118 T 28-03-2018 IPR001341 Aspartate kinase domain GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 Gene3D G3DSA:3.30.70.260 236 335 1.1E-24 T 28-03-2018 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 Gene3D G3DSA:3.30.70.260 336 421 5.4E-20 T 28-03-2018 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 SUPERFAMILY SSF53633 4 244 1.96E-71 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 Pfam PF01842 ACT domain 271 329 1.2E-9 T 28-03-2018 IPR002912 ACT domain CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 407 4.8E-122 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 Pfam PF00696 Amino acid kinase family 3 231 1.2E-53 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 Gene3D G3DSA:3.40.1160.10 1 235 9.1E-73 T 28-03-2018 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 SUPERFAMILY SSF55021 333 409 2.35E-21 T 28-03-2018 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 PIRSF PIRSF000726 57 414 2.4E-127 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 PIRSF PIRSF000726 1 61 3.6E-20 T 28-03-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 28-03-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153 CNX65_RS01015 75da52267d6bedf80710b1110d0663ce 421 Pfam PF13840 ACT domain 341 403 2.5E-13 T 28-03-2018 IPR027795 GATS-like ACT domain CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 SUPERFAMILY SSF90123 13 324 1.31E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 Gene3D G3DSA:3.40.50.300 334 586 5.7E-65 T 28-03-2018 CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 ProSitePatterns PS00211 ABC transporters family signature. 482 496 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 SMART SM00382 370 556 7.3E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 SUPERFAMILY SSF52540 336 578 1.64E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 Pfam PF00664 ABC transporter transmembrane region 28 297 3.3E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 Gene3D G3DSA:1.20.1560.10 1 330 2.2E-60 T 28-03-2018 CNX65_RS02640 03b8869101f9c1e64a4f38106b1b68a0 589 Pfam PF00005 ABC transporter 361 509 8.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 Gene3D G3DSA:1.10.10.10 79 173 3.2E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 SUPERFAMILY SSF46767 81 163 3.27E-32 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 83 162 5.5E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 Pfam PF02870 6-O-methylguanine DNA methyltransferase, ribonuclease-like domain 11 78 1.2E-8 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 132 138 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 Gene3D G3DSA:3.30.160.70 8 78 3.1E-21 T 28-03-2018 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 82 161 5.6E-33 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 SUPERFAMILY SSF53155 9 86 4.32E-18 T 28-03-2018 IPR008332 Methylguanine DNA methyltransferase, ribonuclease-like domain GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS08210 f61d77e633b5c986ab2d29e01cd38c5f 173 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 12 162 40.306 T 28-03-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 Gene3D G3DSA:3.30.70.1430 557 653 1.9E-8 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 PRINTS PR00702 Acriflavin resistance protein family signature 349 370 1.0E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 PRINTS PR00702 Acriflavin resistance protein family signature 455 478 1.0E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 1.0E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 PRINTS PR00702 Acriflavin resistance protein family signature 377 401 1.0E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 PRINTS PR00702 Acriflavin resistance protein family signature 322 345 1.0E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 1.0E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 PRINTS PR00702 Acriflavin resistance protein family signature 430 453 1.0E-42 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 Gene3D G3DSA:3.30.2090.10 179 260 3.0E-13 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 Gene3D G3DSA:3.30.2090.10 700 783 3.0E-9 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 SUPERFAMILY SSF82866 781 1007 3.66E-50 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 SUPERFAMILY SSF82866 285 483 2.49E-42 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 SUPERFAMILY SSF82693 41 130 1.91E-19 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 Gene3D G3DSA:1.20.1640.10 795 1016 1.1E-41 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 Gene3D G3DSA:1.20.1640.10 275 495 3.1E-44 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 Gene3D G3DSA:3.30.70.1430 41 142 2.4E-21 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 SUPERFAMILY SSF82693 134 180 1.78E-11 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 SUPERFAMILY SSF82693 262 304 1.78E-11 T 28-03-2018 CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 SUPERFAMILY SSF82714 181 257 3.14E-9 T 28-03-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains CNX65_RS12895 0c35843addf7c00da6dd75f495c9bfc0 1028 Pfam PF00873 AcrB/AcrD/AcrF family 5 1002 1.5E-206 T 28-03-2018 IPR001036 Acriflavin resistance protein GO:0005215|GO:0006810|GO:0016020 CNX65_RS25650 2185607210fd7e765a3763da6bc65b80 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 5.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS25650 2185607210fd7e765a3763da6bc65b80 193 Gene3D G3DSA:1.10.10.60 3 42 1.1E-10 T 28-03-2018 CNX65_RS25650 2185607210fd7e765a3763da6bc65b80 193 Gene3D G3DSA:1.10.357.10 69 193 5.5E-13 T 28-03-2018 CNX65_RS25650 2185607210fd7e765a3763da6bc65b80 193 SUPERFAMILY SSF46689 3 84 1.5E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS25650 2185607210fd7e765a3763da6bc65b80 193 SUPERFAMILY SSF48498 80 190 1.67E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS25650 2185607210fd7e765a3763da6bc65b80 193 Gene3D G3DSA:1.10.260.40 43 68 2.4E-11 T 28-03-2018 CNX65_RS03780 4ade2c7b1e921afd1f6273d264c41a5f 283 TIGRFAM TIGR03445 mycothiol_MshB: N-acetyl-1-D-myo-inositol-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase 10 281 2.2E-101 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS03780 4ade2c7b1e921afd1f6273d264c41a5f 283 Pfam PF02585 GlcNAc-PI de-N-acetylase 10 160 4.4E-26 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CNX65_RS03780 4ade2c7b1e921afd1f6273d264c41a5f 283 Gene3D G3DSA:3.40.50.10320 3 283 2.1E-69 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS03780 4ade2c7b1e921afd1f6273d264c41a5f 283 Hamap MF_01696 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase [mshB]. 9 281 40.271 T 28-03-2018 IPR017810 Mycothiol biosynthesis protein, MshB GO:0035595 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS03780 4ade2c7b1e921afd1f6273d264c41a5f 283 SUPERFAMILY SSF102588 6 270 1.2E-61 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 2407 2660 1.56E-58 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF47336 6893 6964 5.5E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 6015 6026 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 4772 4990 3.4E-42 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 2681 2826 2.0E-42 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 5884 6018 3.5E-32 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 1622 1774 2.3E-46 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 7441 7588 5.2E-45 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 3729 3865 4.4E-38 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 463 684 4.0E-42 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF47336 3185 3257 4.06E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00668 Condensation domain 6982 7432 5.3E-87 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00668 Condensation domain 3273 3717 3.2E-87 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00668 Condensation domain 2222 2671 1.7E-86 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00668 Condensation domain 1167 1612 1.3E-80 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00668 Condensation domain 5428 5876 4.0E-91 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00668 Condensation domain 8 334 8.6E-43 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00668 Condensation domain 4314 4761 1.6E-87 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 4310 4511 7.23E-49 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF47336 1077 1149 2.16E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 3697 4244 4.32E-153 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:2.30.38.10 1944 2025 2.1E-22 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:2.30.38.10 7750 7831 9.0E-22 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:2.30.38.10 2995 3076 5.2E-24 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:2.30.38.10 846 927 2.6E-21 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5349 5364 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF47336 5318 5391 6.67E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF53474 8012 8276 7.54E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 6837 6912 6.67E-139 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 5855 6306 6.67E-139 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 1614 2152 3.4E-160 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF47336 7940 8011 2.22E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.559.10 2211 2419 1.3E-44 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.559.10 4299 4512 1.9E-48 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.559.10 3266 3472 1.0E-44 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.559.10 6963 7180 3.1E-45 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.559.10 5408 5626 4.9E-50 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF08241 Methyltransferase domain 6369 6471 1.0E-8 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 3270 3471 1.01E-47 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF47336 4225 4296 1.11E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.1820 8017 8277 1.2E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 4985 4996 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:1.10.1200.10 3197 3265 1.0E-24 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 7167 7419 7.89E-58 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00823 Phosphopantetheine attachment site 2139 2208 1.5E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00823 Phosphopantetheine attachment site 7946 8015 1.0E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00823 Phosphopantetheine attachment site 4231 4300 4.6E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00823 Phosphopantetheine attachment site 5325 5394 7.6E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00823 Phosphopantetheine attachment site 1084 1153 1.4E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00823 Phosphopantetheine attachment site 6899 6968 1.6E-7 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00823 Phosphopantetheine attachment site 3191 3260 4.3E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 7833 7951 8.4E-35 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 4118 4236 3.0E-41 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 929 1087 9.7E-38 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 3078 3196 2.0E-41 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 5220 5328 6.7E-31 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 6744 6904 2.1E-17 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 2027 2144 7.1E-41 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:1.10.1200.10 1088 1154 3.5E-23 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:1.10.1200.10 5329 5393 2.9E-24 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 11 185 6.56E-30 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 3862 3873 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00975 Thioesterase domain 8034 8261 3.5E-29 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 1352 1602 2.45E-56 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.300.30 6246 6326 3.7E-16 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6923 6938 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 462 604 8.9E-136 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 648 987 8.9E-136 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 1022 1097 8.9E-136 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 4954 5338 1.44E-135 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 4745 4890 1.44E-135 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3215 3230 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2163 2178 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00501 AMP-binding enzyme 5895 6252 4.3E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00501 AMP-binding enzyme 1630 2032 9.7E-99 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00501 AMP-binding enzyme 2690 3083 8.2E-98 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00501 AMP-binding enzyme 7450 7838 1.0E-95 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00501 AMP-binding enzyme 3737 4123 2.7E-84 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00501 AMP-binding enzyme 4780 5225 4.5E-91 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00501 AMP-binding enzyme 473 934 5.0E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 7970 7985 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1108 1123 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1769 1780 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2821 2832 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:2.30.38.10 6163 6242 1.7E-22 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:2.30.38.10 5136 5215 6.0E-23 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:2.30.38.10 4032 4112 1.0E-24 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 5431 5600 2.33E-51 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 2652 3204 5.36E-161 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 1162 1365 6.34E-50 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 4991 5132 2.7E-28 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 2827 2990 6.6E-40 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 1775 1938 5.5E-41 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 685 844 7.2E-28 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF47336 2133 2204 3.66E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00455 Putative AMP-binding domain signature. 7584 7595 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 6019 6154 1.9E-31 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 3866 4020 5.7E-33 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.980 7589 7738 8.1E-38 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 3758 4147 1.8E-122 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2710 3107 7.0E-137 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 7471 7862 2.7E-126 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1651 2056 1.0E-137 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 5914 6276 6.2E-113 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 4497 4745 2.56E-59 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.40.50.150 6329 6583 3.1E-24 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 5612 5864 4.0E-56 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4255 4270 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00550 Phosphopantetheine attachment site 1086 1149 1.0E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00550 Phosphopantetheine attachment site 3193 3255 4.1E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00550 Phosphopantetheine attachment site 6901 6964 1.4E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00550 Phosphopantetheine attachment site 7948 8011 2.9E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00550 Phosphopantetheine attachment site 4234 4295 1.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00550 Phosphopantetheine attachment site 2141 2203 1.6E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF00550 Phosphopantetheine attachment site 5327 5389 1.2E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF53335 6332 6484 9.29E-23 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:1.10.1200.10 4237 4298 1.8E-21 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:1.10.1200.10 2145 2210 1.1E-23 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:1.10.1200.10 6905 6962 1.3E-24 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:1.10.1200.10 7952 8014 3.4E-21 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 191 410 8.23E-30 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 3459 3723 2.11E-58 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF56801 7410 7953 3.01E-151 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF13193 AMP-binding enzyme C-terminal domain 7846 7921 4.0E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF13193 AMP-binding enzyme C-terminal domain 5233 5302 1.7E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF13193 AMP-binding enzyme C-terminal domain 3091 3166 1.4E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF13193 AMP-binding enzyme C-terminal domain 942 1060 8.4E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF13193 AMP-binding enzyme C-terminal domain 4131 4206 8.1E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Pfam PF13193 AMP-binding enzyme C-terminal domain 2040 2115 1.2E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SMART SM00824 Thioesterase 8036 8280 4.2E-5 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 6985 7156 1.09E-49 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 SUPERFAMILY SSF52777 2225 2396 5.56E-47 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.559.10 1155 1340 3.5E-46 T 28-03-2018 CNX65_RS18225 de9dfa961be3cc592ec20501429e6771 8295 Gene3D G3DSA:3.30.559.10 1 196 2.0E-24 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.50.720 2828 2874 6.4E-4 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 3408 3538 1.1E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 1311 1586 7.5E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2983 3141 1.5E-9 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF55048 4473 4526 2.22E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM01294 3911 3977 0.0012 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00698 Acyl transferase domain 4356 4600 1.1E-40 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00698 Acyl transferase domain 609 857 3.6E-49 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00698 Acyl transferase domain 3633 3755 9.9E-29 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00698 Acyl transferase domain 1679 1920 6.2E-43 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 467 583 7.4E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3509 3601 4.4E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.30.70.250 1804 1844 9.1E-14 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00550 Phosphopantetheine attachment site 3916 3977 3.6E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF08659 KR domain 2983 3131 3.6E-16 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF14765 Polyketide synthase dehydratase 2358 2523 2.2E-10 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF14765 Polyketide synthase dehydratase 2001 2125 1.3E-13 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF14765 Polyketide synthase dehydratase 4679 4926 6.5E-21 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF51735 2788 2914 1.66E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF52151 607 729 3.4E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF52151 792 893 3.4E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.50.720 5193 5298 2.1E-17 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 609 888 1.3E-71 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4356 4628 7.4E-56 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3633 3850 1.8E-27 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1678 1951 4.3E-63 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 131 347 6.2E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 3207 3401 3.4E-46 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.90.180.10 2692 2827 1.6E-31 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF50129 5075 5201 1.89E-22 T 28-03-2018 IPR011032 GroES-like CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF50129 2697 2816 6.29E-21 T 28-03-2018 IPR011032 GroES-like CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF51735 2531 2675 7.09E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.50.720 2978 3205 3.7E-14 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF52151 3629 3838 1.2E-50 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.50.720 5350 5604 1.3E-18 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.10.129.10 4681 4794 9.4E-5 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.10.129.10 2001 2119 1.2E-5 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00825 Beta-ketoacyl synthase 3207 3540 3.8E-56 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00825 Beta-ketoacyl synthase 132 518 9.9E-109 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00825 Beta-ketoacyl synthase 1084 1588 4.5E-93 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00825 Beta-ketoacyl synthase 4001 4266 1.3E-17 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 1086 1310 2.9E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 4093 4194 2.0E-4 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 4018 4092 2.0E-14 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.366.10 606 736 1.2E-40 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.366.10 4353 4480 6.0E-35 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF51735 2982 3130 2.18E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF51735 5359 5561 2.23E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF52151 1855 1923 6.28E-46 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF52151 1678 1794 6.28E-46 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 3995 4017 0.0013 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF53901 3203 3534 1.83E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF55048 728 788 1.18E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3412 3499 1.7E-14 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 353 464 5.1E-26 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1307 1416 7.3E-28 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF47336 3911 4014 5.1E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.366.10 1670 1803 9.7E-33 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.366.10 4516 4627 1.3E-14 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.30.70.250 4481 4515 2.3E-11 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.30.70.250 737 785 7.3E-14 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF53901 128 461 3.46E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.90.180.10 5066 5192 5.6E-25 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1217 1233 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.366.10 1845 1956 1.4E-12 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.366.10 786 866 6.4E-13 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00823 Phosphopantetheine attachment site 3910 3981 7.6E-17 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3999 4089 7.6E-14 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 131 342 7.0E-53 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3205 3373 1.5E-35 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4094 4160 2.1E-4 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1082 1298 4.3E-54 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF52151 4535 4604 4.45E-48 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF52151 4354 4474 4.45E-48 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.47.10 362 516 6.4E-42 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF55048 1793 1851 1.27E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF53901 1080 1413 1.15E-72 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF53901 3998 4261 3.22E-30 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.90.180.10 2875 2977 0.0075 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00829 5075 5350 3.2E-66 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00829 2692 2974 1.2E-82 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00826 2001 2427 5.5E-26 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SMART SM00826 4679 4823 1.4E-35 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:1.10.1200.10 3910 3994 7.7E-14 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Pfam PF01370 NAD dependent epimerase/dehydratase family 5360 5434 1.2E-6 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF51735 4868 5059 6.3E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 Gene3D G3DSA:3.40.366.10 3619 3865 3.9E-61 T 28-03-2018 CNX65_RS20120 429c179770afac0ea85bd714bce60dcf 5679 SUPERFAMILY SSF51735 5168 5301 3.09E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS04090 de8990e660765af7f0ca94014fc0cbe3 299 Pfam PF11583 P-aminobenzoate N-oxygenase AurF 8 282 1.1E-106 T 28-03-2018 IPR025859 P-aminobenzoate N-oxygenase AurF CNX65_RS04090 de8990e660765af7f0ca94014fc0cbe3 299 Gene3D G3DSA:1.10.620.20 4 280 8.8E-33 T 28-03-2018 CNX65_RS04090 de8990e660765af7f0ca94014fc0cbe3 299 SUPERFAMILY SSF47240 72 233 2.3E-5 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS27220 b25c8a7bdc6c746c7778903b542b9f26 355 Gene3D G3DSA:3.30.930.10 24 355 6.1E-78 T 28-03-2018 CNX65_RS27220 b25c8a7bdc6c746c7778903b542b9f26 355 Pfam PF01409 tRNA synthetases class II core domain (F) 109 350 3.3E-100 T 28-03-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 CNX65_RS27220 b25c8a7bdc6c746c7778903b542b9f26 355 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 25 351 44.886 T 28-03-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 CNX65_RS27220 b25c8a7bdc6c746c7778903b542b9f26 355 SUPERFAMILY SSF46589 31 115 7.85E-14 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CNX65_RS27220 b25c8a7bdc6c746c7778903b542b9f26 355 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 37 104 1.4E-15 T 28-03-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CNX65_RS27220 b25c8a7bdc6c746c7778903b542b9f26 355 SUPERFAMILY SSF55681 109 351 1.36E-77 T 28-03-2018 CNX65_RS27220 b25c8a7bdc6c746c7778903b542b9f26 355 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 68 349 3.8E-87 T 28-03-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 109 273 1.9E-23 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 Gene3D G3DSA:1.10.520.20 108 222 1.4E-14 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 Gene3D G3DSA:1.10.520.20 21 107 6.4E-6 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 SUPERFAMILY SSF47928 109 183 9.55E-5 T 28-03-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 Hamap MF_01416 ATP synthase subunit delta [atpD]. 69 275 15.262 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 Pfam PF00213 ATP synthase delta (OSCP) subunit 109 273 1.6E-35 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 235 254 - T 28-03-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 PRINTS PR00125 ATP synthase delta subunit signature 103 122 2.3E-11 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 PRINTS PR00125 ATP synthase delta subunit signature 233 248 2.3E-11 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30210 e58ec2b8db78362971e87fa2b193a222 275 PRINTS PR00125 ATP synthase delta subunit signature 248 266 2.3E-11 T 28-03-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 ProSitePatterns PS01014 Transcription termination factor nusG signature. 255 264 - T 28-03-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 SUPERFAMILY SSF82679 89 193 1.83E-37 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 Gene3D G3DSA:3.30.70.940 88 197 1.7E-38 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 Pfam PF02357 Transcription termination factor nusG 89 191 1.0E-25 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 SMART SM00738 87 195 4.0E-51 T 28-03-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 87 272 24.121 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 Gene3D G3DSA:2.30.30.30 213 272 1.9E-19 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 SMART SM00739 218 245 0.0084 T 28-03-2018 IPR005824 KOW CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 SUPERFAMILY SSF50104 216 272 5.52E-17 T 28-03-2018 IPR008991 Translation protein SH3-like domain CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 PRINTS PR00338 Transcription termination factor NUSG signature 142 154 6.1E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 PRINTS PR00338 Transcription termination factor NUSG signature 248 264 6.1E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 PRINTS PR00338 Transcription termination factor NUSG signature 230 245 6.1E-20 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CNX65_RS32585 753049cc43c6893a1c63a90e93fc82d1 272 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 90 272 1.6E-65 T 28-03-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 CNX65_RS27795 76647d93f602deee343a6445bbf045d7 250 SUPERFAMILY SSF52540 14 231 7.68E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27795 76647d93f602deee343a6445bbf045d7 250 Pfam PF00005 ABC transporter 34 179 9.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS27795 76647d93f602deee343a6445bbf045d7 250 SMART SM00382 42 228 2.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS27795 76647d93f602deee343a6445bbf045d7 250 Gene3D G3DSA:3.40.50.300 9 244 6.6E-62 T 28-03-2018 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 SUPERFAMILY SSF51905 261 377 5.26E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 SUPERFAMILY SSF51905 6 167 5.26E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 Gene3D G3DSA:3.50.50.60 2 377 5.2E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 Pfam PF01494 FAD binding domain 7 329 1.8E-76 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 316 332 3.6E-41 T 28-03-2018 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.6E-41 T 28-03-2018 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 3.6E-41 T 28-03-2018 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 265 280 3.6E-41 T 28-03-2018 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 316 3.6E-41 T 28-03-2018 CNX65_RS21030 be87b9d6f08306e81f05cd532c81fdc8 470 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 296 3.6E-41 T 28-03-2018 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 SUPERFAMILY SSF55021 685 763 3.71E-14 T 28-03-2018 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 SUPERFAMILY SSF81301 231 406 1.28E-60 T 28-03-2018 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 Pfam PF04607 Region found in RelA / SpoT proteins 274 383 2.4E-35 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 Gene3D G3DSA:3.30.460.10 227 365 7.1E-39 T 28-03-2018 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 67 761 5.7E-261 T 28-03-2018 IPR004811 RelA/SpoT family GO:0015969 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 Pfam PF02824 TGS domain 429 488 5.3E-24 T 28-03-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 Pfam PF13328 HD domain 67 214 2.3E-47 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 Gene3D G3DSA:3.10.20.30 423 495 2.9E-27 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 SUPERFAMILY SSF109604 43 229 2.42E-70 T 28-03-2018 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 SUPERFAMILY SSF81271 416 488 4.58E-22 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 Pfam PF13291 ACT domain 685 761 2.6E-16 T 28-03-2018 IPR002912 ACT domain CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 SMART SM00954 274 384 3.2E-58 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 SMART SM00471 82 192 3.6E-12 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS08475 da94217d3ce542e990c52a83bb0571d5 766 Gene3D G3DSA:3.30.70.260 689 766 5.0E-13 T 28-03-2018 CNX65_RS26545 9a7f3516c6c8542031fbb4956718d249 292 Gene3D G3DSA:3.40.50.720 1 164 4.2E-20 T 28-03-2018 CNX65_RS26545 9a7f3516c6c8542031fbb4956718d249 292 SUPERFAMILY SSF51735 1 276 1.82E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26545 9a7f3516c6c8542031fbb4956718d249 292 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 76 2.4E-11 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS26545 9a7f3516c6c8542031fbb4956718d249 292 Gene3D G3DSA:3.90.25.10 165 284 2.5E-14 T 28-03-2018 CNX65_RS33620 7f6603ae97094813a4e805cfa8c35213 132 SMART SM00345 15 74 2.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS33620 7f6603ae97094813a4e805cfa8c35213 132 SUPERFAMILY SSF46785 4 78 6.49E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33620 7f6603ae97094813a4e805cfa8c35213 132 Gene3D G3DSA:1.10.10.10 1 88 1.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33620 7f6603ae97094813a4e805cfa8c35213 132 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 74 1.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS19250 73317cb5e70b575b057d373e6301d0d4 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 133 149 6.4E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS19250 73317cb5e70b575b057d373e6301d0d4 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 55 63 6.4E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS19250 73317cb5e70b575b057d373e6301d0d4 169 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 101 116 6.4E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS19250 73317cb5e70b575b057d373e6301d0d4 169 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 11 158 12.928 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS19250 73317cb5e70b575b057d373e6301d0d4 169 TIGRFAM TIGR00077 lspA: signal peptidase II 16 154 2.0E-23 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS19250 73317cb5e70b575b057d373e6301d0d4 169 ProSitePatterns PS00855 Signal peptidases II signature. 104 116 - T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS19250 73317cb5e70b575b057d373e6301d0d4 169 Pfam PF01252 Signal peptidase (SPase) II 20 152 1.1E-27 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 Gene3D G3DSA:2.60.120.260 352 468 1.8E-25 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 Gene3D G3DSA:2.60.120.260 469 579 2.8E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 ProSitePatterns PS01182 Glycosyl hydrolases family 35 putative active site. 147 159 - T 28-03-2018 IPR019801 Glycoside hydrolase, family 35, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 SUPERFAMILY SSF51445 4 328 2.23E-102 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 SUPERFAMILY SSF49785 437 561 1.34E-27 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 Pfam PF01301 Glycosyl hydrolases family 35 11 324 6.9E-113 T 28-03-2018 IPR031330 Glycoside hydrolase 35, catalytic domain KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 35 53 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 293 309 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 14 31 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 267 282 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 90 109 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 145 160 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 231 246 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PRINTS PR00742 Glycosyl hydrolase family 35 signature 517 533 1.2E-57 T 28-03-2018 IPR001944 Glycoside hydrolase, family 35 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 PIRSF PIRSF006336 1 579 1.2E-179 T 28-03-2018 IPR026283 Beta-galactosidase 1-like GO:0004565 CNX65_RS13070 851a6826bd8879b1cc66687d8590f62c 579 Gene3D G3DSA:3.20.20.80 1 330 3.4E-82 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:3.40.47.10 299 458 4.9E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:3.40.366.10 734 853 1.9E-33 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1691 1706 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SUPERFAMILY SSF47336 1656 1737 2.09E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SUPERFAMILY SSF55048 689 747 2.35E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF14765 Polyketide synthase dehydratase 916 1188 4.2E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SMART SM00823 Phosphopantetheine attachment site 1664 1736 3.6E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SMART SM00826 916 1079 3.6E-81 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:3.40.47.10 26 296 2.9E-89 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SMART SM00825 Beta-ketoacyl synthase 36 460 1.4E-222 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SUPERFAMILY SSF51735 1378 1629 5.63E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:3.30.70.250 697 733 1.7E-16 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:3.10.129.10 916 1046 5.6E-8 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 6.5E-89 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1383 1561 1.6E-52 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF08659 KR domain 1383 1559 6.0E-54 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF08990 Erythronolide synthase docking 3 27 8.1E-11 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:3.40.366.10 562 696 8.2E-51 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 566 849 1.1E-122 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SUPERFAMILY SSF52151 749 838 2.88E-80 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SUPERFAMILY SSF52151 562 690 2.88E-80 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SMART SM01294 1665 1732 9.9E-5 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:3.40.50.720 1375 1648 1.5E-50 T 28-03-2018 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 2.2E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SUPERFAMILY SSF53901 29 406 4.49E-106 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF00698 Acyl transferase domain 565 841 7.9E-60 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 531 1.5E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Pfam PF00550 Phosphopantetheine attachment site 1666 1731 5.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 SUPERFAMILY SSF51735 1197 1369 2.79E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13575 1b77f54faa83cafada2971b9222bd26d 1812 Gene3D G3DSA:1.10.1200.10 1649 1743 1.2E-19 T 28-03-2018 CNX65_RS22710 05119e98a2d8fd8b0e5620b9a96a92a1 143 Pfam PF01255 Putative undecaprenyl diphosphate synthase 1 74 1.6E-19 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS22710 05119e98a2d8fd8b0e5620b9a96a92a1 143 Gene3D G3DSA:3.40.1180.10 1 87 3.8E-18 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS22710 05119e98a2d8fd8b0e5620b9a96a92a1 143 SUPERFAMILY SSF64005 1 73 4.05E-16 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 222 448 1.5E-81 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 SUPERFAMILY SSF47005 162 204 2.35E-10 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 SUPERFAMILY SSF52777 213 448 2.98E-82 T 28-03-2018 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 Pfam PF00364 Biotin-requiring enzyme 5 78 7.9E-20 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 SUPERFAMILY SSF51230 4 96 8.11E-26 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 29 58 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 Pfam PF02817 e3 binding domain 167 202 3.6E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 Gene3D G3DSA:2.40.50.100 7 65 1.8E-19 T 28-03-2018 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 Gene3D G3DSA:3.30.559.10 211 451 8.6E-85 T 28-03-2018 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 Gene3D G3DSA:3.90.1170.30 66 92 0.16 T 28-03-2018 CNX65_RS34495 5949a0f6f94fedc59f2fccf91774bf25 452 Gene3D G3DSA:4.10.320.10 163 210 1.4E-16 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 86 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 PRINTS PR00598 Bacterial regulatory protein MarR family signature 137 157 2.4E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 SMART SM00347 44 146 1.2E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 Gene3D G3DSA:1.10.10.10 7 160 3.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 SUPERFAMILY SSF46785 17 159 2.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03955 c6bd2474d408d3abcebe259580ea249c 160 Pfam PF12802 MarR family 51 110 8.4E-14 T 28-03-2018 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 SMART SM00642 13 427 5.0E-160 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 SUPERFAMILY SSF51011 488 554 1.15E-14 T 28-03-2018 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 Gene3D G3DSA:3.90.400.10 103 174 7.9E-32 T 28-03-2018 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 SUPERFAMILY SSF51445 4 484 7.77E-151 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 Pfam PF16657 Maltogenic Amylase, C-terminal domain 488 530 3.0E-9 T 28-03-2018 IPR032091 Maltogenic Amylase, C-terminal CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 Gene3D G3DSA:3.20.20.470 175 350 3.0E-40 T 28-03-2018 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 Gene3D G3DSA:3.20.20.80 351 487 1.3E-21 T 28-03-2018 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 Pfam PF00128 Alpha amylase, catalytic domain 28 384 1.7E-112 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 Gene3D G3DSA:2.60.40.1180 489 555 9.7E-17 T 28-03-2018 CNX65_RS15160 63981deabd4ffef539e1a431cbf1bf5a 555 Gene3D G3DSA:3.20.20.470 2 95 2.5E-35 T 28-03-2018 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SUPERFAMILY SSF55781 177 320 1.33E-16 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF00072 Response regulator receiver domain 617 728 3.1E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF13581 Histidine kinase-like ATPase domain 1259 1374 3.5E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF08448 PAS fold 53 156 1.6E-7 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.30.565.10 1254 1379 2.5E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:1.10.287.130 332 389 3.4E-18 T 28-03-2018 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF00512 His Kinase A (phospho-acceptor) domain 330 393 2.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SMART SM00331 1036 1251 5.1E-33 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 547 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 489 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 510 528 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 PRINTS PR00344 Bacterial sensor protein C-terminal signature 493 503 1.5E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 1066 1251 2.6E-43 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SUPERFAMILY SSF52172 614 745 6.4E-38 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 742 863 7.1E-12 T 28-03-2018 IPR000014 PAS domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SMART SM00448 615 728 2.5E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SMART SM00091 743 810 0.0047 T 28-03-2018 IPR000014 PAS domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.30.450.20 42 159 3.3E-7 T 28-03-2018 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.30.450.20 739 867 1.2E-18 T 28-03-2018 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.30.450.40 868 1015 0.21 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SUPERFAMILY SSF55785 737 860 1.15E-14 T 28-03-2018 IPR000014 PAS domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SMART SM00387 439 550 9.3E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.30.450.40 160 331 7.7E-29 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SMART SM00065 177 317 1.3E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SUPERFAMILY SSF55874 1282 1372 5.11E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SUPERFAMILY SSF47384 314 394 2.35E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.30.565.10 397 556 6.6E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SUPERFAMILY SSF55874 384 548 2.62E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.40.50.2300 601 738 3.4E-35 T 28-03-2018 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 SMART SM00388 329 393 7.8E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF00989 PAS fold 746 859 1.9E-6 T 28-03-2018 IPR013767 PAS fold GO:0006355 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 446 549 2.4E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Gene3D G3DSA:3.60.40.10 1016 1252 3.8E-28 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS19780 2ede89ecd46d522340d00528a0ee87ba 1379 Pfam PF13185 GAF domain 175 307 2.9E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS04030 41e1a7d8e378a781449a02228da961c6 367 Gene3D G3DSA:1.20.58.340 183 299 1.8E-31 T 28-03-2018 CNX65_RS04030 41e1a7d8e378a781449a02228da961c6 367 Gene3D G3DSA:3.30.460.20 34 175 4.3E-37 T 28-03-2018 CNX65_RS04030 41e1a7d8e378a781449a02228da961c6 367 Gene3D G3DSA:1.20.58.340 300 367 2.7E-18 T 28-03-2018 CNX65_RS04030 41e1a7d8e378a781449a02228da961c6 367 SUPERFAMILY SSF143865 37 299 2.22E-67 T 28-03-2018 CNX65_RS04030 41e1a7d8e378a781449a02228da961c6 367 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 61 367 2.0E-61 T 28-03-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 CNX65_RS04030 41e1a7d8e378a781449a02228da961c6 367 SUPERFAMILY SSF144083 302 364 1.83E-19 T 28-03-2018 CNX65_RS04030 41e1a7d8e378a781449a02228da961c6 367 Pfam PF01544 CorA-like Mg2+ transporter protein 69 361 5.2E-63 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CNX65_RS25165 1db29d1029dd5eae986cfaa4f07227d7 456 Gene3D G3DSA:1.10.860.10 3 154 3.0E-13 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CNX65_RS25165 1db29d1029dd5eae986cfaa4f07227d7 456 SUPERFAMILY SSF52540 186 254 1.45E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25165 1db29d1029dd5eae986cfaa4f07227d7 456 SUPERFAMILY SSF52540 294 431 1.45E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25165 1db29d1029dd5eae986cfaa4f07227d7 456 Gene3D G3DSA:3.40.50.300 168 453 6.5E-38 T 28-03-2018 CNX65_RS25165 1db29d1029dd5eae986cfaa4f07227d7 456 Pfam PF03796 DnaB-like helicase C terminal domain 195 437 2.9E-59 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CNX65_RS25165 1db29d1029dd5eae986cfaa4f07227d7 456 SUPERFAMILY SSF48024 14 122 3.66E-5 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 SUPERFAMILY SSF56801 15 515 4.84E-154 T 28-03-2018 CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 Gene3D G3DSA:3.40.50.980 181 331 4.2E-54 T 28-03-2018 CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 Pfam PF00501 AMP-binding enzyme 26 421 4.3E-112 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 Gene3D G3DSA:2.30.38.10 332 414 4.8E-26 T 28-03-2018 CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 Pfam PF13193 AMP-binding enzyme C-terminal domain 430 505 5.7E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 Gene3D G3DSA:3.30.300.30 415 517 3.7E-27 T 28-03-2018 CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS33290 7e88f5a866f7b227e548b1d738c21e9b 517 Gene3D G3DSA:3.40.50.980 14 180 2.0E-41 T 28-03-2018 CNX65_RS29170 941a68a0937b8ded3ba44fc55b341d6b 513 Gene3D G3DSA:3.20.20.360 69 398 1.1E-103 T 28-03-2018 CNX65_RS29170 941a68a0937b8ded3ba44fc55b341d6b 513 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 17 512 5.4E-215 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS29170 941a68a0937b8ded3ba44fc55b341d6b 513 PIRSF PIRSF001363 1 513 2.4E-211 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS29170 941a68a0937b8ded3ba44fc55b341d6b 513 Pfam PF01274 Malate synthase 6 512 3.4E-176 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS29170 941a68a0937b8ded3ba44fc55b341d6b 513 ProSitePatterns PS00510 Malate synthase signature. 248 263 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS29170 941a68a0937b8ded3ba44fc55b341d6b 513 SUPERFAMILY SSF51645 10 512 5.75E-169 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS29170 941a68a0937b8ded3ba44fc55b341d6b 513 Gene3D G3DSA:1.20.1220.12 399 512 3.1E-39 T 28-03-2018 CNX65_RS24185 95fba3dad0781d89ed444b93c1e32aeb 352 Gene3D G3DSA:3.20.20.70 1 352 1.3E-107 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS24185 95fba3dad0781d89ed444b93c1e32aeb 352 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 7 326 1.6E-71 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CNX65_RS24185 95fba3dad0781d89ed444b93c1e32aeb 352 SUPERFAMILY SSF51395 6 351 3.91E-104 T 28-03-2018 CNX65_RS30555 125a978177dd6061388859da231be20b 725 Pfam PF14490 Helix-hairpin-helix containing domain 143 233 7.0E-30 T 28-03-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain CNX65_RS30555 125a978177dd6061388859da231be20b 725 SUPERFAMILY SSF52540 434 501 3.28E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30555 125a978177dd6061388859da231be20b 725 SUPERFAMILY SSF52540 542 708 3.28E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30555 125a978177dd6061388859da231be20b 725 Gene3D G3DSA:3.40.50.300 494 708 8.0E-35 T 28-03-2018 CNX65_RS30555 125a978177dd6061388859da231be20b 725 SUPERFAMILY SSF47781 85 161 9.39E-10 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS30555 125a978177dd6061388859da231be20b 725 Gene3D G3DSA:1.10.150.280 124 211 1.1E-5 T 28-03-2018 CNX65_RS30555 125a978177dd6061388859da231be20b 725 Pfam PF13538 UvrD-like helicase C-terminal domain 647 695 1.4E-20 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CNX65_RS30555 125a978177dd6061388859da231be20b 725 Gene3D G3DSA:3.40.50.300 284 493 1.1E-36 T 28-03-2018 CNX65_RS30555 125a978177dd6061388859da231be20b 725 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 11 720 3.2E-200 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CNX65_RS30555 125a978177dd6061388859da231be20b 725 Gene3D G3DSA:1.10.150.20 92 123 0.0028 T 28-03-2018 CNX65_RS30555 125a978177dd6061388859da231be20b 725 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 4 724 28.57 T 28-03-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 CNX65_RS30555 125a978177dd6061388859da231be20b 725 SUPERFAMILY SSF52540 183 477 2.94E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30555 125a978177dd6061388859da231be20b 725 SMART SM00382 338 535 8.6E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30555 125a978177dd6061388859da231be20b 725 Pfam PF14520 Helix-hairpin-helix domain 93 142 7.5E-5 T 28-03-2018 CNX65_RS30555 125a978177dd6061388859da231be20b 725 Pfam PF13604 AAA domain 325 504 1.7E-43 T 28-03-2018 CNX65_RS12790 e09d01a5946c5415cf459f94e1107689 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 60 2.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12790 e09d01a5946c5415cf459f94e1107689 194 ProSitePatterns PS01081 TetR-type HTH domain signature. 31 62 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS12790 e09d01a5946c5415cf459f94e1107689 194 Gene3D G3DSA:1.10.10.60 2 60 3.0E-17 T 28-03-2018 CNX65_RS12790 e09d01a5946c5415cf459f94e1107689 194 SUPERFAMILY SSF46689 7 79 2.86E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12790 e09d01a5946c5415cf459f94e1107689 194 Gene3D G3DSA:1.10.357.10 61 194 3.6E-22 T 28-03-2018 CNX65_RS31785 e0e78af0290955927de05a566602f86f 406 TIGRFAM TIGR00127 nadp_idh_euk: isocitrate dehydrogenase, NADP-dependent 3 405 1.1E-207 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CNX65_RS31785 e0e78af0290955927de05a566602f86f 406 PIRSF PIRSF000108 1 406 2.4E-222 T 28-03-2018 IPR004790 Isocitrate dehydrogenase NADP-dependent GO:0004450|GO:0006102|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 CNX65_RS31785 e0e78af0290955927de05a566602f86f 406 SMART SM01329 9 396 1.5E-133 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CNX65_RS31785 e0e78af0290955927de05a566602f86f 406 Gene3D G3DSA:3.40.718.10 1 406 9.6E-133 T 28-03-2018 CNX65_RS31785 e0e78af0290955927de05a566602f86f 406 SUPERFAMILY SSF53659 2 404 4.32E-150 T 28-03-2018 CNX65_RS31785 e0e78af0290955927de05a566602f86f 406 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 10 389 5.8E-71 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CNX65_RS31785 e0e78af0290955927de05a566602f86f 406 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 271 290 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 25 39 1.5E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 191 208 1.5E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 318 330 1.5E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 159 176 1.5E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 208 218 1.5E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 1.5E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 PRINTS PR01043 Glycyl-tRNA synthetase signature 138 150 1.5E-51 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 3 459 49.219 T 28-03-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 6 234 6.2E-80 T 28-03-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 Pfam PF03129 Anticodon binding domain 367 456 3.5E-23 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 SUPERFAMILY SSF55681 5 370 1.02E-119 T 28-03-2018 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 Gene3D G3DSA:3.30.930.10 3 224 1.7E-53 T 28-03-2018 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 Gene3D G3DSA:3.30.930.10 225 358 1.9E-39 T 28-03-2018 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 158 298 2.0E-9 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 SUPERFAMILY SSF52954 354 458 9.36E-33 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS06300 d655e71d885806ce26bb0dccfc4b974e 461 Gene3D G3DSA:3.40.50.800 359 459 2.9E-25 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 SMART SM00632 380 459 1.7E-35 T 28-03-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 PRINTS PR00110 Alpha-amylase signature 112 123 4.1E-22 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 PRINTS PR00110 Alpha-amylase signature 80 97 4.1E-22 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 PRINTS PR00110 Alpha-amylase signature 288 300 4.1E-22 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 PRINTS PR00110 Alpha-amylase signature 230 248 4.1E-22 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 PRINTS PR00110 Alpha-amylase signature 201 212 4.1E-22 T 28-03-2018 IPR006046 Alpha amylase GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+3.2.1.1|Reactome: R-HSA-189085 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 SMART SM01065 467 559 6.1E-27 T 28-03-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 Pfam PF00686 Starch binding domain 471 555 5.7E-28 T 28-03-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 SUPERFAMILY SSF51011 376 458 6.6E-26 T 28-03-2018 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 Gene3D G3DSA:2.60.40.1180 378 459 1.9E-29 T 28-03-2018 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 SUPERFAMILY SSF49452 465 552 5.15E-28 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 SUPERFAMILY SSF51445 36 373 1.25E-86 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 Gene3D G3DSA:3.20.20.80 33 376 1.7E-73 T 28-03-2018 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 383 456 9.7E-10 T 28-03-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 Pfam PF00128 Alpha amylase, catalytic domain 89 341 5.6E-22 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 Gene3D G3DSA:2.60.40.10 461 558 2.2E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS05625 446e0705cb84aff2b41d9f38d5a95a84 559 SMART SM00642 37 371 7.1E-92 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS11785 a8c307cb9a3a5624787f5bc10d805fd0 120 Gene3D G3DSA:3.40.50.2300 1 120 3.9E-33 T 28-03-2018 CNX65_RS11785 a8c307cb9a3a5624787f5bc10d805fd0 120 Pfam PF00072 Response regulator receiver domain 3 114 3.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11785 a8c307cb9a3a5624787f5bc10d805fd0 120 SMART SM00448 1 115 3.3E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11785 a8c307cb9a3a5624787f5bc10d805fd0 120 SUPERFAMILY SSF52172 1 119 2.13E-34 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS24200 d34447b89632a2e0507d07956d94f7f3 204 SUPERFAMILY SSF47413 27 83 4.57E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS24200 d34447b89632a2e0507d07956d94f7f3 204 Gene3D G3DSA:1.10.357.10 27 196 5.3E-7 T 28-03-2018 CNX65_RS31595 8e64978cfd8c5ba661095b0ad380cc06 107 Gene3D G3DSA:1.10.287.1060 1 103 2.2E-10 T 28-03-2018 CNX65_RS31595 8e64978cfd8c5ba661095b0ad380cc06 107 SUPERFAMILY SSF140453 55 103 8.76E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 Gene3D G3DSA:4.10.1090.10 280 345 3.8E-14 T 28-03-2018 CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 Gene3D G3DSA:4.10.1090.10 346 384 1.1E-12 T 28-03-2018 CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 Gene3D G3DSA:2.80.10.50 385 422 2.3E-12 T 28-03-2018 CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 Pfam PF00722 Glycosyl hydrolases family 16 74 278 1.5E-43 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 Pfam PF00652 Ricin-type beta-trefoil lectin domain 300 420 1.5E-28 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 SMART SM00458 294 423 5.8E-29 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 Gene3D G3DSA:2.60.120.200 33 279 8.3E-77 T 28-03-2018 CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 SUPERFAMILY SSF49899 39 282 5.74E-76 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS26495 aca36f96b4ff52a782f34703236312e1 424 SUPERFAMILY SSF50370 303 421 6.16E-37 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS04945 33c3db505c16aee07407b3e38c9ea54d 210 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 16 200 3.1E-32 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS04945 33c3db505c16aee07407b3e38c9ea54d 210 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 210 71.539 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CNX65_RS04945 33c3db505c16aee07407b3e38c9ea54d 210 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 18 206 9.1E-48 T 28-03-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|KEGG: 00400+4.2.1.10|MetaCyc: PWY-4361|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707|Reactome: R-HSA-1237112 CNX65_RS04945 33c3db505c16aee07407b3e38c9ea54d 210 Gene3D G3DSA:3.40.225.10 8 207 2.5E-38 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS04945 33c3db505c16aee07407b3e38c9ea54d 210 SUPERFAMILY SSF53639 15 204 1.96E-36 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS04945 33c3db505c16aee07407b3e38c9ea54d 210 SMART SM01007 15 203 1.9E-37 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 SUPERFAMILY SSF47323 421 550 2.29E-34 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Hamap MF_00123 Arginine--tRNA ligase [argS]. 8 550 25.843 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Gene3D G3DSA:3.40.50.620 119 315 4.2E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 31 550 2.4E-128 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 18 93 8.0E-22 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 137 153 1.0E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 296 317 1.0E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 122 137 1.0E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 PRINTS PR01038 Arginyl-tRNA synthetase signature 161 174 1.0E-22 T 28-03-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 SUPERFAMILY SSF52374 116 438 2.95E-82 T 28-03-2018 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Pfam PF00750 tRNA synthetases class I (R) 115 389 7.6E-16 T 28-03-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 SMART SM01016 4 93 4.6E-31 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Gene3D G3DSA:1.10.730.10 402 550 6.0E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Gene3D G3DSA:3.40.50.620 316 401 4.1E-15 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 SUPERFAMILY SSF55190 8 113 1.16E-23 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Pfam PF05746 DALR anticodon binding domain 427 550 2.6E-37 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 Gene3D G3DSA:3.30.1360.70 4 117 1.6E-29 T 28-03-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 SMART SM00836 427 550 1.4E-51 T 28-03-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 CNX65_RS30310 5fb43592452755c1b9f12f48434130f4 550 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 132 141 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 SUPERFAMILY SSF55326 7 169 3.14E-45 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 Pfam PF02769 AIR synthase related protein, C-terminal domain 177 343 1.4E-34 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 Pfam PF00586 AIR synthase related protein, N-terminal domain 62 165 4.6E-16 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 7 347 41.863 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 Gene3D G3DSA:3.30.1330.10 37 162 2.6E-47 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 SUPERFAMILY SSF56042 173 344 4.93E-55 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 8 338 2.8E-136 T 28-03-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS33900 e8770ad343d145ae44a38fc4b40d5c72 352 Gene3D G3DSA:3.90.650.10 172 346 5.6E-59 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 SMART SM00419 206 254 5.8E-8 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 Gene3D G3DSA:2.60.120.10 73 180 4.6E-14 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 SMART SM00100 52 170 9.1E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 Pfam PF00027 Cyclic nucleotide-binding domain 77 155 3.6E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 Gene3D G3DSA:1.10.10.10 181 261 8.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 SUPERFAMILY SSF46785 188 260 7.49E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 SUPERFAMILY SSF51206 57 169 3.27E-18 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS19795 0ad59636db515f5702d8da74a6c09ca4 267 Pfam PF13545 Crp-like helix-turn-helix domain 193 259 8.4E-11 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS05600 d703b89ad01c452b8fb41e86ade59a99 210 Gene3D G3DSA:1.10.10.60 1 56 2.6E-15 T 28-03-2018 CNX65_RS05600 d703b89ad01c452b8fb41e86ade59a99 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 1.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS05600 d703b89ad01c452b8fb41e86ade59a99 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 1.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS05600 d703b89ad01c452b8fb41e86ade59a99 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 69 1.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS05600 d703b89ad01c452b8fb41e86ade59a99 210 SUPERFAMILY SSF46689 10 74 1.03E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS05600 d703b89ad01c452b8fb41e86ade59a99 210 Gene3D G3DSA:1.10.10.60 57 158 3.5E-9 T 28-03-2018 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 SUPERFAMILY SSF53790 266 503 2.62E-53 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 Gene3D G3DSA:3.30.950.10 142 220 0.055 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 271 507 6.4E-84 T 28-03-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 98 130 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 271 475 1.3E-37 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 215 2.3E-51 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 Gene3D G3DSA:3.30.950.10 388 506 1.6E-51 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 Gene3D G3DSA:3.40.1010.10 2 141 9.5E-33 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 Gene3D G3DSA:3.40.1010.10 269 387 3.8E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 SUPERFAMILY SSF53790 1 236 4.84E-49 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08875 f340ca2ecc8321b5a208057555e6d6f9 510 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 231 5.3E-66 T 28-03-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 SUPERFAMILY SSF56014 427 571 6.54E-37 T 28-03-2018 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 480 496 - T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 181 332 6.9E-39 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 431 568 1.6E-10 T 28-03-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 SUPERFAMILY SSF56014 181 341 4.58E-46 T 28-03-2018 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 Gene3D G3DSA:3.30.413.10 429 573 8.3E-30 T 28-03-2018 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 SUPERFAMILY SSF55124 30 180 1.59E-37 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 SUPERFAMILY SSF55124 348 424 2.62E-18 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 PRINTS PR00397 Sirohaem Fe-binding site signature 431 449 1.1E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 PRINTS PR00397 Sirohaem Fe-binding site signature 480 498 1.1E-9 T 28-03-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 Gene3D G3DSA:3.90.480.10 297 426 3.7E-29 T 28-03-2018 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 354 419 1.7E-12 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 110 172 5.2E-18 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS06175 5503f7d4fda805650282f55135398a2d 574 Gene3D G3DSA:3.30.413.10 183 296 8.7E-25 T 28-03-2018 CNX65_RS00985 b9e1325b3768f38888fb7ea22730104a 380 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 249 337 4.3E-26 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS00985 b9e1325b3768f38888fb7ea22730104a 380 Gene3D G3DSA:3.40.50.300 16 353 2.0E-81 T 28-03-2018 CNX65_RS00985 b9e1325b3768f38888fb7ea22730104a 380 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 250 315 4.5E-15 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS00985 b9e1325b3768f38888fb7ea22730104a 380 ProSitePatterns PS00211 ABC transporters family signature. 171 185 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS00985 b9e1325b3768f38888fb7ea22730104a 380 SUPERFAMILY SSF52540 18 270 9.4E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00985 b9e1325b3768f38888fb7ea22730104a 380 Pfam PF00005 ABC transporter 47 198 1.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS00985 b9e1325b3768f38888fb7ea22730104a 380 SMART SM00382 55 248 1.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 Pfam PF00067 Cytochrome P450 43 452 9.2E-59 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 Gene3D G3DSA:1.10.630.10 44 464 3.7E-96 T 28-03-2018 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 SUPERFAMILY SSF48264 41 462 1.31E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00463 E-class P450 group I signature 296 322 8.4E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00463 E-class P450 group I signature 326 344 8.4E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00463 E-class P450 group I signature 409 432 8.4E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00463 E-class P450 group I signature 399 409 8.4E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00463 E-class P450 group I signature 68 87 8.4E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00463 E-class P450 group I signature 276 293 8.4E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00385 P450 superfamily signature 327 338 5.6E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00385 P450 superfamily signature 400 409 5.6E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00385 P450 superfamily signature 287 304 5.6E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 PRINTS PR00385 P450 superfamily signature 409 420 5.6E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS19560 6953f444446438df23a42ef7632ccf54 474 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 402 411 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 SUPERFAMILY SSF52540 647 894 3.25E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Pfam PF13374 Tetratricopeptide repeat 1166 1200 9.5E-4 T 28-03-2018 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Pfam PF13374 Tetratricopeptide repeat 1414 1454 4.9E-5 T 28-03-2018 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Pfam PF00931 NB-ARC domain 663 823 1.5E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 SUPERFAMILY SSF48452 1326 1443 1.45E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Gene3D G3DSA:1.10.10.10 1306 1387 1.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Gene3D G3DSA:1.10.10.10 1388 1473 8.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Gene3D G3DSA:1.10.10.10 1045 1133 3.8E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Gene3D G3DSA:1.10.10.10 1134 1216 2.1E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Gene3D G3DSA:1.10.10.10 1218 1305 3.9E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 SUPERFAMILY SSF48452 1210 1352 3.04E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Pfam PF13424 Tetratricopeptide repeat 1248 1319 1.3E-10 T 28-03-2018 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Pfam PF13424 Tetratricopeptide repeat 1080 1149 1.9E-7 T 28-03-2018 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Pfam PF13424 Tetratricopeptide repeat 1332 1401 3.8E-8 T 28-03-2018 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 SUPERFAMILY SSF48452 1036 1182 4.4E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS21190 44ec6496564576bf03d66d9dd9a48464 1474 Gene3D G3DSA:3.40.50.300 639 803 3.0E-14 T 28-03-2018 CNX65_RS08840 ebc2179fe6376ed369b37d919ec97f53 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 273 1.7E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08840 ebc2179fe6376ed369b37d919ec97f53 281 Gene3D G3DSA:1.10.3720.10 6 279 7.7E-43 T 28-03-2018 CNX65_RS08840 ebc2179fe6376ed369b37d919ec97f53 281 SUPERFAMILY SSF161098 62 261 1.23E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08840 ebc2179fe6376ed369b37d919ec97f53 281 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 62 170 2.0E-18 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CNX65_RS14205 544478a174b33f5fe79a61048c48842c 232 Pfam PF08241 Methyltransferase domain 49 141 4.6E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS14205 544478a174b33f5fe79a61048c48842c 232 Gene3D G3DSA:3.40.50.150 12 219 1.1E-29 T 28-03-2018 CNX65_RS14205 544478a174b33f5fe79a61048c48842c 232 SUPERFAMILY SSF53335 13 195 4.14E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS08830 286065d2135096817dd7a29d0e59efcd 577 Gene3D G3DSA:3.40.640.10 26 262 2.7E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS08830 286065d2135096817dd7a29d0e59efcd 577 Pfam PF13309 HTH domain 511 569 2.4E-18 T 28-03-2018 CNX65_RS08830 286065d2135096817dd7a29d0e59efcd 577 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 393 483 1.0E-16 T 28-03-2018 IPR013559 YheO-like CNX65_RS08830 286065d2135096817dd7a29d0e59efcd 577 Gene3D G3DSA:3.90.1150.10 263 371 5.1E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS08830 286065d2135096817dd7a29d0e59efcd 577 Pfam PF00266 Aminotransferase class-V 28 329 2.6E-17 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS08830 286065d2135096817dd7a29d0e59efcd 577 Pfam PF08348 YheO-like PAS domain 383 483 5.9E-28 T 28-03-2018 IPR013559 YheO-like CNX65_RS08830 286065d2135096817dd7a29d0e59efcd 577 SUPERFAMILY SSF53383 16 360 4.63E-52 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 Gene3D G3DSA:3.90.1150.10 778 910 1.9E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 TIGRFAM TIGR00461 gcvP: glycine dehydrogenase 20 954 0.0 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 Hamap MF_00711 Glycine dehydrogenase (decarboxylating) [gcvP]. 11 960 25.382 T 28-03-2018 IPR003437 Glycine dehydrogenase (decarboxylating) GO:0004375|GO:0006544|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 Gene3D G3DSA:3.40.640.10 99 349 6.4E-35 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 Gene3D G3DSA:3.90.1150.10 350 453 1.4E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 SUPERFAMILY SSF53383 20 448 3.25E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 Gene3D G3DSA:3.40.640.10 536 777 1.5E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 SUPERFAMILY SSF53383 933 956 1.05E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 SUPERFAMILY SSF53383 463 892 1.05E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 Pfam PF02347 Glycine cleavage system P-protein 455 738 8.5E-9 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CNX65_RS26650 62da0738806b783ece6d77cb4e564c9a 962 Pfam PF02347 Glycine cleavage system P-protein 19 448 7.7E-173 T 28-03-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 CNX65_RS04055 2dd6c6c79e6d45868a87b676109008d5 278 Pfam PF12697 Alpha/beta hydrolase family 27 265 2.3E-17 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04055 2dd6c6c79e6d45868a87b676109008d5 278 PRINTS PR00412 Epoxide hydrolase signature 218 234 3.1E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04055 2dd6c6c79e6d45868a87b676109008d5 278 PRINTS PR00412 Epoxide hydrolase signature 250 272 3.1E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04055 2dd6c6c79e6d45868a87b676109008d5 278 PRINTS PR00412 Epoxide hydrolase signature 98 111 3.1E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04055 2dd6c6c79e6d45868a87b676109008d5 278 PRINTS PR00412 Epoxide hydrolase signature 50 65 3.1E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04055 2dd6c6c79e6d45868a87b676109008d5 278 SUPERFAMILY SSF53474 24 270 1.41E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04055 2dd6c6c79e6d45868a87b676109008d5 278 Gene3D G3DSA:3.40.50.1820 1 277 4.0E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 Gene3D G3DSA:3.50.50.60 145 275 4.4E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 SUPERFAMILY SSF51905 2 340 2.02E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 Gene3D G3DSA:3.50.50.60 1 144 5.8E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 2.1E-8 T 28-03-2018 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 161 179 2.1E-8 T 28-03-2018 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 269 285 2.1E-8 T 28-03-2018 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 4 197 4.6E-24 T 28-03-2018 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 2 24 2.8E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 157 181 2.8E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS05145 cf219c8bf518c357194a41c1b16d7608 345 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 118 126 2.8E-14 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS19655 88dfc9e14c5d6902e9733693449f8b0c 274 Pfam PF00005 ABC transporter 29 175 5.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS19655 88dfc9e14c5d6902e9733693449f8b0c 274 SMART SM00382 35 220 1.2E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS19655 88dfc9e14c5d6902e9733693449f8b0c 274 Gene3D G3DSA:3.40.50.300 8 247 1.8E-60 T 28-03-2018 CNX65_RS19655 88dfc9e14c5d6902e9733693449f8b0c 274 SUPERFAMILY SSF52540 7 233 1.88E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS19655 88dfc9e14c5d6902e9733693449f8b0c 274 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SMART SM00825 Beta-ketoacyl synthase 6 464 2.7E-64 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:1.10.1200.10 916 1017 2.6E-5 T 28-03-2018 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF54637 1451 1540 1.09E-5 T 28-03-2018 IPR029069 HotDog domain CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Pfam PF14765 Polyketide synthase dehydratase 1457 1727 1.4E-44 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.40.47.10 1 302 2.5E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.40.50.720 1194 1435 5.2E-29 T 28-03-2018 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF55048 689 752 3.27E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Pfam PF08659 KR domain 1204 1383 3.4E-28 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 298 412 9.2E-31 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1202 1385 2.5E-10 T 28-03-2018 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.40.47.10 304 462 6.2E-45 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF53901 2 128 6.1E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF53901 187 411 6.1E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.10.129.10 1449 1571 1.8E-14 T 28-03-2018 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF51735 1199 1442 2.79E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 583 878 1.3E-32 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF52151 753 853 3.4E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF52151 580 690 3.4E-44 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 290 1.4E-53 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF47336 932 1010 6.66E-5 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.40.366.10 744 867 4.3E-25 T 28-03-2018 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.90.470.20 1763 1844 4.4E-8 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Pfam PF00698 Acyl transferase domain 616 836 3.7E-28 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SUPERFAMILY SSF51735 1041 1174 1.28E-5 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 421 535 5.0E-7 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.40.366.10 579 700 2.9E-14 T 28-03-2018 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 SMART SM00826 1449 1608 5.2E-4 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS20445 d5134b4edf8954dee37677d4205f0b73 1926 Gene3D G3DSA:3.30.70.250 701 743 1.3E-18 T 28-03-2018 CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SUPERFAMILY SSF55785 5 101 5.48E-8 T 28-03-2018 IPR000014 PAS domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Pfam PF00563 EAL domain 412 643 5.4E-61 T 28-03-2018 IPR001633 EAL domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Pfam PF00990 Diguanylate cyclase, GGDEF domain 240 391 1.7E-37 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Pfam PF08447 PAS fold 136 223 1.9E-11 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SMART SM00052 405 648 2.1E-68 T 28-03-2018 IPR001633 EAL domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Gene3D G3DSA:3.20.20.450 402 651 9.5E-76 T 28-03-2018 IPR001633 EAL domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SUPERFAMILY SSF55785 124 231 2.62E-16 T 28-03-2018 IPR000014 PAS domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 239 394 1.6E-37 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SUPERFAMILY SSF141868 411 651 7.06E-69 T 28-03-2018 IPR001633 EAL domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SMART SM00091 4 69 0.022 T 28-03-2018 IPR000014 PAS domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SMART SM00091 113 180 12.0 T 28-03-2018 IPR000014 PAS domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Gene3D G3DSA:3.30.450.20 3 108 2.3E-10 T 28-03-2018 CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SUPERFAMILY SSF55073 245 397 4.55E-43 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 SMART SM00267 229 395 3.9E-55 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Gene3D G3DSA:3.30.70.270 246 401 2.9E-51 T 28-03-2018 CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Gene3D G3DSA:3.30.450.20 109 245 3.2E-20 T 28-03-2018 CNX65_RS17305 b9de9118d039e3f03ec59941721abbca 673 Pfam PF13426 PAS domain 19 60 0.52 T 28-03-2018 IPR000014 PAS domain CNX65_RS34030 01765c7e90c4d44da4c75194ea36d0a0 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 279 3.8E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS34030 01765c7e90c4d44da4c75194ea36d0a0 286 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 72 175 2.1E-17 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CNX65_RS34030 01765c7e90c4d44da4c75194ea36d0a0 286 Gene3D G3DSA:1.10.3720.10 30 285 2.5E-37 T 28-03-2018 CNX65_RS34030 01765c7e90c4d44da4c75194ea36d0a0 286 SUPERFAMILY SSF161098 74 266 6.02E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 PIRSF PIRSF001456 1 390 2.2E-119 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 ProSitePatterns PS00789 Chorismate synthase signature 3. 344 360 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 ProSitePatterns PS00788 Chorismate synthase signature 2. 134 150 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 SUPERFAMILY SSF103263 2 392 4.45E-131 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 Pfam PF01264 Chorismate synthase 2 370 9.8E-112 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 Gene3D G3DSA:3.60.150.10 1 398 6.1E-133 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 Hamap MF_00300 Chorismate synthase [aroC]. 2 377 33.482 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 ProSitePatterns PS00787 Chorismate synthase signature 1. 8 23 - T 28-03-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS26155 7a1460e7cc3b7463c2d4408aaa3aebac 399 TIGRFAM TIGR00033 aroC: chorismate synthase 2 375 1.3E-118 T 28-03-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 CNX65_RS35040 b7a24d0f147ca8d13d75eaa4294d2b5d 331 Pfam PF02195 ParB-like nuclease domain 62 151 1.2E-24 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CNX65_RS35040 b7a24d0f147ca8d13d75eaa4294d2b5d 331 Gene3D G3DSA:1.10.10.730 152 199 1.6E-17 T 28-03-2018 CNX65_RS35040 b7a24d0f147ca8d13d75eaa4294d2b5d 331 SUPERFAMILY SSF110849 51 154 8.55E-30 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CNX65_RS35040 b7a24d0f147ca8d13d75eaa4294d2b5d 331 SUPERFAMILY SSF109709 143 250 2.35E-32 T 28-03-2018 CNX65_RS35040 b7a24d0f147ca8d13d75eaa4294d2b5d 331 Gene3D G3DSA:3.90.1530.10 52 151 1.8E-37 T 28-03-2018 CNX65_RS35040 b7a24d0f147ca8d13d75eaa4294d2b5d 331 SMART SM00470 61 151 1.4E-32 T 28-03-2018 IPR003115 ParB/Sulfiredoxin CNX65_RS35040 b7a24d0f147ca8d13d75eaa4294d2b5d 331 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 59 236 5.7E-61 T 28-03-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 CNX65_RS10925 ff82566f961b9b40b8ba5e215c4777f8 193 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 185 2.2E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10925 ff82566f961b9b40b8ba5e215c4777f8 193 Gene3D G3DSA:1.10.1740.10 1 119 2.7E-22 T 28-03-2018 CNX65_RS10925 ff82566f961b9b40b8ba5e215c4777f8 193 Pfam PF04542 Sigma-70 region 2 22 84 1.1E-14 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10925 ff82566f961b9b40b8ba5e215c4777f8 193 Pfam PF08281 Sigma-70, region 4 130 179 1.4E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10925 ff82566f961b9b40b8ba5e215c4777f8 193 SUPERFAMILY SSF88946 3 92 2.51E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10925 ff82566f961b9b40b8ba5e215c4777f8 193 Gene3D G3DSA:1.10.10.10 120 191 7.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10925 ff82566f961b9b40b8ba5e215c4777f8 193 SUPERFAMILY SSF88659 126 187 1.85E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 129 157 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 SUPERFAMILY SSF51735 11 201 8.06E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 161 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 163 180 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 116 132 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 2.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 142 161 2.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 122 130 2.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 Gene3D G3DSA:3.40.50.720 10 212 3.0E-33 T 28-03-2018 CNX65_RS14405 4939c1f2f25d091df84f6c4459dadeaf 230 Pfam PF00106 short chain dehydrogenase 12 182 6.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21675 07edd976711f545805614f192d210070 171 SUPERFAMILY SSF55961 21 156 2.75E-17 T 28-03-2018 CNX65_RS21675 07edd976711f545805614f192d210070 171 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 23 160 1.3E-15 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CNX65_RS21675 07edd976711f545805614f192d210070 171 Gene3D G3DSA:3.30.530.20 11 170 6.8E-23 T 28-03-2018 IPR023393 START-like domain CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 Gene3D G3DSA:3.90.1300.10 2 493 4.6E-164 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 ProSitePatterns PS00571 Amidases signature. 154 185 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 Pfam PF01425 Amidase 25 474 2.4E-157 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 14 484 2.0E-185 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 PIRSF PIRSF001221 450 487 0.53 T 28-03-2018 CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 PIRSF PIRSF001221 1 452 5.2E-44 T 28-03-2018 CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 12 487 91.427 T 28-03-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS29680 0d395a4adebd0231283434f15ecbc53d 506 SUPERFAMILY SSF75304 1 484 1.27E-158 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS15875 6118428cd5bcf101243e743a25263e07 457 Gene3D G3DSA:3.90.1150.10 293 415 9.4E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15875 6118428cd5bcf101243e743a25263e07 457 Gene3D G3DSA:3.40.640.10 45 292 2.8E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS15875 6118428cd5bcf101243e743a25263e07 457 SUPERFAMILY SSF53383 44 415 1.21E-80 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS15875 6118428cd5bcf101243e743a25263e07 457 Pfam PF00266 Aminotransferase class-V 47 409 5.2E-79 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 2.3E-6 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 SMART SM00829 10 313 8.1E-14 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 Gene3D G3DSA:3.90.180.10 247 315 4.4E-4 T 28-03-2018 CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 Gene3D G3DSA:3.40.50.720 151 246 8.3E-16 T 28-03-2018 CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 142 163 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 Pfam PF13602 Zinc-binding dehydrogenase 184 313 8.8E-19 T 28-03-2018 CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 Gene3D G3DSA:3.90.180.10 1 150 3.0E-44 T 28-03-2018 CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 SUPERFAMILY SSF50129 2 142 5.02E-30 T 28-03-2018 IPR011032 GroES-like CNX65_RS27190 9a81ec8697f62442236acdaaaac40092 315 SUPERFAMILY SSF51735 118 289 3.71E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 488 1.3E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 Gene3D G3DSA:2.30.38.10 318 395 4.1E-12 T 28-03-2018 CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 Gene3D G3DSA:3.40.50.980 153 312 1.1E-25 T 28-03-2018 CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 Gene3D G3DSA:3.40.50.980 12 152 2.5E-37 T 28-03-2018 CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 Gene3D G3DSA:3.30.300.30 398 500 6.6E-25 T 28-03-2018 CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 ProSitePatterns PS00455 Putative AMP-binding domain signature. 147 158 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 SUPERFAMILY SSF56801 18 495 2.22E-111 T 28-03-2018 CNX65_RS22350 7f682aa86b7ebbc79ebef2de91bc45a9 502 Pfam PF00501 AMP-binding enzyme 21 405 7.6E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS11435 a4483a8c73fb3aca81ff40d7a49906d6 294 SUPERFAMILY SSF55961 147 279 1.19E-24 T 28-03-2018 CNX65_RS11435 a4483a8c73fb3aca81ff40d7a49906d6 294 Gene3D G3DSA:3.30.530.20 2 151 2.4E-12 T 28-03-2018 IPR023393 START-like domain CNX65_RS11435 a4483a8c73fb3aca81ff40d7a49906d6 294 Gene3D G3DSA:3.30.530.20 152 272 2.2E-18 T 28-03-2018 IPR023393 START-like domain CNX65_RS11435 a4483a8c73fb3aca81ff40d7a49906d6 294 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 161 263 3.3E-10 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS11435 a4483a8c73fb3aca81ff40d7a49906d6 294 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 13 111 2.8E-9 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS11435 a4483a8c73fb3aca81ff40d7a49906d6 294 SUPERFAMILY SSF55961 12 151 2.24E-15 T 28-03-2018 CNX65_RS02580 2bea173e32f14d21bf5599867653aeeb 103 Pfam PF00699 Urease beta subunit 3 98 7.4E-39 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02580 2bea173e32f14d21bf5599867653aeeb 103 Gene3D G3DSA:2.10.150.10 1 101 1.1E-41 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02580 2bea173e32f14d21bf5599867653aeeb 103 TIGRFAM TIGR00192 urease_beta: urease, beta subunit 2 100 4.9E-33 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02580 2bea173e32f14d21bf5599867653aeeb 103 SUPERFAMILY SSF51278 2 102 5.49E-42 T 28-03-2018 IPR002019 Urease, beta subunit KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 SUPERFAMILY SSF53732 1 465 5.23E-162 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 287 301 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 109 117 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 210 223 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 400 413 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 120 133 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 83 96 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 196 209 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 344 355 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 PRINTS PR00415 Aconitase family signature 134 149 4.5E-47 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 1 467 60.302 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 ProSitePatterns PS01244 Aconitase family signature 2. 400 413 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 Gene3D G3DSA:3.30.499.10 321 467 2.5E-50 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 Pfam PF00330 Aconitase family (aconitate hydratase) 7 458 1.3E-157 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 1 460 1.8E-225 T 28-03-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 ProSitePatterns PS00450 Aconitase family signature 1. 340 356 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 Gene3D G3DSA:3.30.499.10 1 154 2.0E-42 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29530 0f031b20f9e95662a53c63922765bada 467 Gene3D G3DSA:3.40.1060.10 155 289 4.6E-44 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 114 122 - T 28-03-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 Pfam PF00334 Nucleoside diphosphate kinase 3 134 3.7E-51 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 SMART SM00562 2 136 1.9E-71 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 SUPERFAMILY SSF54919 3 135 4.06E-53 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 91 107 4.6E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 5 27 4.6E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 49 68 4.6E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 114 133 4.6E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 PRINTS PR01243 Nucleoside diphosphate kinase signature 69 86 4.6E-42 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 Gene3D G3DSA:3.30.70.141 1 136 7.7E-51 T 28-03-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS05840 9710822f7aa640c1809fefccd342a574 136 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 2 136 32.826 T 28-03-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 SUPERFAMILY SSF51556 56 369 4.16E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 Gene3D G3DSA:2.30.40.10 3 70 1.1E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 ProSitePatterns PS00483 Dihydroorotase signature 2. 304 315 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 Gene3D G3DSA:3.20.20.140 71 391 6.0E-92 T 28-03-2018 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 Pfam PF01979 Amidohydrolase family 52 423 2.6E-21 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 SUPERFAMILY SSF51338 370 430 2.24E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 SUPERFAMILY SSF51338 14 55 2.24E-21 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 16 425 3.0E-137 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26100 68d4138b96ff6344467703359e3a8f72 432 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 428 41.659 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 SUPERFAMILY SSF48173 182 420 1.1E-93 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 Gene3D G3DSA:3.40.50.620 1 136 2.2E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 SUPERFAMILY SSF52425 5 158 1.14E-45 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 Gene3D G3DSA:1.25.40.80 137 182 6.1E-5 T 28-03-2018 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 Gene3D G3DSA:1.25.40.80 183 256 6.4E-20 T 28-03-2018 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 ProSitePatterns PS00394 DNA photolyases class 1 signature 1. 287 299 - T 28-03-2018 IPR018394 Cryptochrome/DNA photolyase class 1, conserved site, C-terminal CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 PRINTS PR00147 DNA photolyase signature 346 360 1.1E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 PRINTS PR00147 DNA photolyase signature 307 325 1.1E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 PRINTS PR00147 DNA photolyase signature 131 147 1.1E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 PRINTS PR00147 DNA photolyase signature 287 303 1.1E-26 T 28-03-2018 IPR002081 Cryptochrome/DNA photolyase class 1 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 Gene3D G3DSA:1.10.579.10 257 421 3.9E-70 T 28-03-2018 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 Pfam PF03441 FAD binding domain of DNA photolyase 238 416 3.4E-75 T 28-03-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CNX65_RS02685 fa39835bf067b7982e6aaedbeb14d0ac 421 Pfam PF00875 DNA photolyase 5 151 6.0E-43 T 28-03-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-1368108|Reactome: R-HSA-400253 CNX65_RS20465 fe7f59b4d2d88f3959bc5c481b348242 173 Pfam PF01638 HxlR-like helix-turn-helix 18 105 2.9E-14 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS20465 fe7f59b4d2d88f3959bc5c481b348242 173 SUPERFAMILY SSF46785 6 130 6.82E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20465 fe7f59b4d2d88f3959bc5c481b348242 173 Gene3D G3DSA:1.10.10.10 2 170 2.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 Pfam PF01494 FAD binding domain 4 345 1.0E-54 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 Gene3D G3DSA:3.50.50.60 2 389 1.9E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 2.6E-21 T 28-03-2018 CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 2.6E-21 T 28-03-2018 CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 312 2.6E-21 T 28-03-2018 CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 154 169 2.6E-21 T 28-03-2018 CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 SUPERFAMILY SSF51905 268 364 1.97E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29565 d326dc40e4c49d0345e1a084b636ccbd 410 SUPERFAMILY SSF51905 4 175 1.97E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS33665 0b4c64c6ffa89f44be419c2c30c724e5 166 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 4.4E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS33665 0b4c64c6ffa89f44be419c2c30c724e5 166 Gene3D G3DSA:1.10.357.10 52 166 1.6E-7 T 28-03-2018 CNX65_RS33665 0b4c64c6ffa89f44be419c2c30c724e5 166 Gene3D G3DSA:1.10.10.60 1 33 4.2E-14 T 28-03-2018 CNX65_RS33665 0b4c64c6ffa89f44be419c2c30c724e5 166 Gene3D G3DSA:1.10.10.60 34 51 9.8E-11 T 28-03-2018 CNX65_RS33665 0b4c64c6ffa89f44be419c2c30c724e5 166 SUPERFAMILY SSF46689 2 72 3.64E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 Gene3D G3DSA:3.65.10.10 297 512 3.4E-32 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 SUPERFAMILY SSF55205 78 510 7.68E-92 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 Gene3D G3DSA:3.65.10.10 77 181 4.6E-11 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 Gene3D G3DSA:3.65.10.10 182 296 1.6E-11 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 82 500 6.1E-42 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 Gene3D G3DSA:1.10.260.40 3 65 5.4E-15 T 28-03-2018 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 SMART SM00530 16 71 3.2E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 SUPERFAMILY SSF47413 8 66 6.19E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09470 174c3cd7708689700ef26de0759eb423 513 Pfam PF01381 Helix-turn-helix 17 65 4.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS19290 1bb8e99ecc6b71c9393cac5e18a5a5d4 372 SUPERFAMILY SSF55469 271 360 8.63E-5 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS19290 1bb8e99ecc6b71c9393cac5e18a5a5d4 372 SUPERFAMILY SSF55469 207 241 8.63E-5 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS19290 1bb8e99ecc6b71c9393cac5e18a5a5d4 372 Gene3D G3DSA:3.40.109.10 203 359 6.4E-12 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS26715 389139334346a18eeabd008995102440 219 Pfam PF13398 Peptidase M50B-like 10 210 6.8E-63 T 28-03-2018 CNX65_RS21130 9b13b4accaa9f15492cb05f5d5dc7e29 110 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 6 93 4.0E-7 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CNX65_RS21130 9b13b4accaa9f15492cb05f5d5dc7e29 110 Gene3D G3DSA:1.10.287.1060 2 110 4.8E-6 T 28-03-2018 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 Gene3D G3DSA:3.40.50.720 4 150 1.7E-23 T 28-03-2018 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 Gene3D G3DSA:3.30.360.10 151 327 3.0E-41 T 28-03-2018 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 13 124 2.8E-20 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 153 330 2.2E-26 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 SUPERFAMILY SSF55347 140 330 2.7E-41 T 28-03-2018 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 PIRSF PIRSF000148 9 348 2.6E-74 T 28-03-2018 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 SMART SM00859 11 128 9.9E-13 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS08050 b91094a1a32116b063d32a462398f80d 357 SUPERFAMILY SSF51735 12 166 9.17E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12335 cd8fdf782466cf2716157e193f0bf347 455 SUPERFAMILY SSF56176 3 215 2.38E-71 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS12335 cd8fdf782466cf2716157e193f0bf347 455 Gene3D G3DSA:3.30.43.10 1 91 8.4E-22 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS12335 cd8fdf782466cf2716157e193f0bf347 455 Pfam PF01565 FAD binding domain 39 178 1.3E-44 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS12335 cd8fdf782466cf2716157e193f0bf347 455 Gene3D G3DSA:1.10.45.10 415 453 1.4E-14 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CNX65_RS12335 cd8fdf782466cf2716157e193f0bf347 455 SUPERFAMILY SSF55103 219 455 1.01E-59 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CNX65_RS12335 cd8fdf782466cf2716157e193f0bf347 455 Pfam PF02913 FAD linked oxidases, C-terminal domain 218 453 2.0E-59 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CNX65_RS12335 cd8fdf782466cf2716157e193f0bf347 455 Gene3D G3DSA:3.30.465.10 92 238 3.9E-45 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SMART SM01043 126 270 2.1E-50 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SUPERFAMILY SSF48452 764 938 6.96E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SUPERFAMILY SSF46894 29 119 1.25E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Gene3D G3DSA:1.10.150.200 796 836 2.1E-9 T 28-03-2018 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Gene3D G3DSA:1.10.150.200 727 795 9.0E-8 T 28-03-2018 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Pfam PF00486 Transcriptional regulatory protein, C terminal 46 119 1.2E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 PRINTS PR00364 Disease resistance protein signature 330 345 9.3E-8 T 28-03-2018 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 PRINTS PR00364 Disease resistance protein signature 409 423 9.3E-8 T 28-03-2018 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 PRINTS PR00364 Disease resistance protein signature 491 505 9.3E-8 T 28-03-2018 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Pfam PF00931 NB-ARC domain 318 505 2.0E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Gene3D G3DSA:1.25.40.10 837 960 5.9E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SMART SM00028 787 820 5.2 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SMART SM00028 907 939 310.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SMART SM00028 827 860 0.46 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SMART SM00028 747 780 2.5 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SMART SM00028 867 900 380.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Gene3D G3DSA:3.40.50.300 299 462 2.2E-17 T 28-03-2018 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Pfam PF03704 Bacterial transcriptional activator domain 126 270 1.4E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SMART SM00862 39 119 8.1E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SUPERFAMILY SSF52540 304 551 1.07E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Pfam PF13424 Tetratricopeptide repeat 787 859 1.1E-11 T 28-03-2018 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Gene3D G3DSA:1.25.40.10 123 298 3.3E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 SUPERFAMILY SSF48452 121 290 6.75E-36 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27805 c95b8f8393120d31a67ebb2ba47ef765 965 Gene3D G3DSA:1.10.10.10 17 122 2.9E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23165 9ff28acd5ebe5188e7d8b919287162f7 578 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 56 557 1.7E-93 T 28-03-2018 IPR026487 Sporadically distributed protein CHP04141 CNX65_RS12690 1fc37ed530654833a07a46e5579328f7 122 SUPERFAMILY SSF54909 2 116 2.39E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS12690 1fc37ed530654833a07a46e5579328f7 122 Pfam PF03795 YCII-related domain 2 107 1.9E-16 T 28-03-2018 IPR005545 YCII-related CNX65_RS12690 1fc37ed530654833a07a46e5579328f7 122 Gene3D G3DSA:3.30.70.1060 1 118 1.4E-35 T 28-03-2018 CNX65_RS09300 110fb2eac8798c7fc7b1991c50dc44aa 219 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 13 188 6.3E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS09300 110fb2eac8798c7fc7b1991c50dc44aa 219 SMART SM01007 11 190 1.0E-59 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS09300 110fb2eac8798c7fc7b1991c50dc44aa 219 Gene3D G3DSA:3.40.225.10 6 219 4.5E-60 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS09300 110fb2eac8798c7fc7b1991c50dc44aa 219 SUPERFAMILY SSF53639 8 211 1.96E-59 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 SUPERFAMILY SSF52374 1 154 9.12E-42 T 28-03-2018 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 60 4.0E-17 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 111 133 2.4E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 85 101 2.4E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 20 41 2.4E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 2 20 2.4E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 49 73 2.4E-47 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 Gene3D G3DSA:3.40.50.620 1 157 1.1E-31 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 Pfam PF01467 Cytidylyltransferase-like 6 131 8.6E-17 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 3 155 6.6E-60 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CNX65_RS29305 b327a36d0f53edc8f510fece8de836c3 160 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 2 157 33.593 T 28-03-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 CNX65_RS33885 8fa92f14ab73f80eae1c384711354679 136 Gene3D G3DSA:3.30.160.20 2 136 4.7E-32 T 28-03-2018 CNX65_RS33885 8fa92f14ab73f80eae1c384711354679 136 SUPERFAMILY SSF75620 6 96 6.67E-9 T 28-03-2018 CNX65_RS33885 8fa92f14ab73f80eae1c384711354679 136 Pfam PF00472 RF-1 domain 6 130 7.8E-20 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CNX65_RS07440 cf6ad5769717dd7fd2a8c14d1e0bc76c 572 Pfam PF04851 Type III restriction enzyme, res subunit 12 164 2.2E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CNX65_RS07440 cf6ad5769717dd7fd2a8c14d1e0bc76c 572 SMART SM00487 8 185 3.0E-12 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS07440 cf6ad5769717dd7fd2a8c14d1e0bc76c 572 Gene3D G3DSA:3.40.50.300 1 171 2.4E-19 T 28-03-2018 CNX65_RS07440 cf6ad5769717dd7fd2a8c14d1e0bc76c 572 SUPERFAMILY SSF52540 126 196 1.54E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07440 cf6ad5769717dd7fd2a8c14d1e0bc76c 572 SUPERFAMILY SSF52540 256 377 1.54E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07440 cf6ad5769717dd7fd2a8c14d1e0bc76c 572 SUPERFAMILY SSF52540 10 168 3.3E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07440 cf6ad5769717dd7fd2a8c14d1e0bc76c 572 Gene3D G3DSA:3.40.50.300 258 532 1.5E-7 T 28-03-2018 CNX65_RS34060 4a5469640476d97198ff81e8469de5e3 196 Gene3D G3DSA:1.10.357.10 4 196 9.9E-24 T 28-03-2018 CNX65_RS34060 4a5469640476d97198ff81e8469de5e3 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 9.5E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34060 4a5469640476d97198ff81e8469de5e3 196 SUPERFAMILY SSF46689 8 79 1.03E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS34060 4a5469640476d97198ff81e8469de5e3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34060 4a5469640476d97198ff81e8469de5e3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13720 3c1ec526c3efd4dfaef079bf56b369f6 190 SUPERFAMILY SSF48498 81 176 7.34E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS13720 3c1ec526c3efd4dfaef079bf56b369f6 190 Gene3D G3DSA:1.10.357.10 60 182 3.3E-14 T 28-03-2018 CNX65_RS13720 3c1ec526c3efd4dfaef079bf56b369f6 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 1.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13720 3c1ec526c3efd4dfaef079bf56b369f6 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13720 3c1ec526c3efd4dfaef079bf56b369f6 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13720 3c1ec526c3efd4dfaef079bf56b369f6 190 SUPERFAMILY SSF46689 5 73 2.77E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS13720 3c1ec526c3efd4dfaef079bf56b369f6 190 Gene3D G3DSA:1.10.10.60 2 59 4.2E-13 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 Gene3D G3DSA:3.90.210.10 1765 1946 9.8E-17 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 PRINTS PR01217 Proline rich extensin signature 335 347 8.9E-9 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 PRINTS PR01217 Proline rich extensin signature 433 449 8.9E-9 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 PRINTS PR01217 Proline rich extensin signature 451 468 8.9E-9 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 PRINTS PR01217 Proline rich extensin signature 482 507 8.9E-9 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 PRINTS PR01217 Proline rich extensin signature 398 419 8.9E-9 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 SUPERFAMILY SSF56399 1770 1901 2.37E-9 T 28-03-2018 CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 SUPERFAMILY SSF140453 25 95 3.92E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS32490 9a94d3b34e2b0b72ab758cd7e528c907 1950 Gene3D G3DSA:1.10.287.1060 22 117 2.3E-11 T 28-03-2018 CNX65_RS22540 764d9be42573e2e796b8acfdb790b0ed 331 SUPERFAMILY SSF55347 128 293 8.99E-25 T 28-03-2018 CNX65_RS22540 764d9be42573e2e796b8acfdb790b0ed 331 Gene3D G3DSA:3.40.50.720 2 141 1.5E-30 T 28-03-2018 CNX65_RS22540 764d9be42573e2e796b8acfdb790b0ed 331 SUPERFAMILY SSF51735 5 153 4.38E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22540 764d9be42573e2e796b8acfdb790b0ed 331 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 119 1.6E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS22540 764d9be42573e2e796b8acfdb790b0ed 331 Gene3D G3DSA:3.30.360.10 142 331 3.2E-21 T 28-03-2018 CNX65_RS21615 2a01b1f4aafa7b6e42df3c7f11b3876e 331 Gene3D G3DSA:1.10.10.60 221 279 1.2E-13 T 28-03-2018 CNX65_RS21615 2a01b1f4aafa7b6e42df3c7f11b3876e 331 Pfam PF12833 Helix-turn-helix domain 248 329 1.1E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS21615 2a01b1f4aafa7b6e42df3c7f11b3876e 331 Gene3D G3DSA:1.10.10.60 280 331 1.9E-7 T 28-03-2018 CNX65_RS21615 2a01b1f4aafa7b6e42df3c7f11b3876e 331 SUPERFAMILY SSF46689 225 276 1.84E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21615 2a01b1f4aafa7b6e42df3c7f11b3876e 331 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 279 324 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS21615 2a01b1f4aafa7b6e42df3c7f11b3876e 331 SMART SM00342 242 328 3.2E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS21615 2a01b1f4aafa7b6e42df3c7f11b3876e 331 SUPERFAMILY SSF46689 279 328 3.14E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS07335 c22f1cccb8ceeca7475656c2ad35e7ee 284 Gene3D G3DSA:1.10.3100.10 6 153 6.5E-10 T 28-03-2018 IPR027910 YdiL-like domain CNX65_RS07335 c22f1cccb8ceeca7475656c2ad35e7ee 284 Pfam PF13560 Helix-turn-helix domain 12 72 1.6E-12 T 28-03-2018 CNX65_RS07335 c22f1cccb8ceeca7475656c2ad35e7ee 284 SUPERFAMILY SSF47413 9 66 1.33E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 Gene3D G3DSA:3.40.50.300 153 301 2.6E-33 T 28-03-2018 CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 Gene3D G3DSA:3.40.50.300 16 152 2.6E-28 T 28-03-2018 CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 SUPERFAMILY SSF52540 19 682 7.26E-171 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 Pfam PF13361 UvrD-like helicase C-terminal domain 298 654 5.2E-62 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 19 770 1.2E-290 T 28-03-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 Pfam PF00580 UvrD/REP helicase N-terminal domain 23 291 4.9E-76 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 Gene3D G3DSA:3.40.50.300 435 703 6.1E-50 T 28-03-2018 CNX65_RS31955 6a18c76d9467a1956baf6cd170805001 780 Gene3D G3DSA:3.40.50.300 302 405 2.2E-26 T 28-03-2018 CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 Gene3D G3DSA:1.10.260.40 10 69 4.8E-18 T 28-03-2018 CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 SMART SM00354 10 82 2.1E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 59 3.3E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 SUPERFAMILY SSF53822 72 336 3.3E-47 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 Gene3D G3DSA:3.40.50.2300 70 174 3.5E-19 T 28-03-2018 CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 Pfam PF13377 Periplasmic binding protein-like domain 178 334 1.5E-28 T 28-03-2018 CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 Gene3D G3DSA:3.40.50.2300 175 337 1.2E-37 T 28-03-2018 CNX65_RS23535 c0f25944e5116d028a8653e10a2f77a3 342 SUPERFAMILY SSF47413 10 69 8.44E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 Pfam PF00557 Metallopeptidase family M24 11 246 5.6E-41 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 Gene3D G3DSA:3.90.230.10 1 256 3.0E-69 T 28-03-2018 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 254 4.9E-84 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 Hamap MF_01974 Methionine aminopeptidase [map]. 2 255 37.662 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 SUPERFAMILY SSF55920 1 253 3.93E-75 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 197 209 1.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 90 106 1.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 PRINTS PR00599 Methionine aminopeptidase-1 signature 166 178 1.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS32340 0c4a7ec8a0b4b9f43c40b2a0849fa9ac 258 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 172 190 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS14685 80d624866b8daee6cb4d7cae1febcb6c 72 Pfam PF05593 RHS Repeat 31 66 2.4E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS14685 80d624866b8daee6cb4d7cae1febcb6c 72 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 13 49 9.2E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00826 1879 2037 4.7E-69 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00826 3915 4077 2.5E-55 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:2.30.38.10 320 402 5.6E-26 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00829 2298 2595 3.1E-150 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.90.180.10 2290 2597 3.0E-56 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF47336 2864 2975 4.84E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF47336 919 1008 1.19E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF55048 3694 3748 2.75E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.47.10 3227 3388 1.6E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2605 2783 1.7E-48 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4340 4510 2.9E-47 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF08659 KR domain 4340 4509 7.7E-46 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF08659 KR domain 2605 2781 2.4E-51 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.366.10 3568 3705 5.6E-36 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.50.720 4333 4682 3.8E-56 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF52151 1533 1658 8.11E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF52151 1713 1809 8.11E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3124 3140 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF51735 2603 2852 1.66E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3572 3853 4.9E-85 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1537 1820 2.9E-107 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.30.300.30 403 510 6.5E-26 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF55048 1656 1708 8.24E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00698 Acyl transferase domain 3571 3872 1.5E-45 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00698 Acyl transferase domain 1536 1838 1.9E-74 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF52151 3752 3849 4.19E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF52151 3569 3696 4.19E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 491 1.7E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.366.10 3749 3862 8.0E-22 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.366.10 1701 1824 1.1E-28 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.366.10 1521 1700 7.3E-49 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.47.10 1013 1273 1.6E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.47.10 2962 3223 5.5E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF51735 4338 4554 1.39E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00501 AMP-binding enzyme 15 409 2.6E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF51735 2401 2570 5.86E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.50.720 694 775 0.21 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00823 Phosphopantetheine attachment site 2866 2938 1.3E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00823 Phosphopantetheine attachment site 926 997 4.3E-17 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00823 Phosphopantetheine attachment site 4581 4653 3.7E-22 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.50.980 7 167 9.8E-39 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 2317 2373 1.9E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF53901 2957 3332 1.39E-96 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1269 1385 1.8E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3220 3335 1.2E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF50129 2313 2433 1.32E-24 T 28-03-2018 IPR011032 GroES-like CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF51735 2150 2278 1.73E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF14765 Polyketide synthase dehydratase 3915 4186 8.9E-41 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF14765 Polyketide synthase dehydratase 1879 2146 9.3E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.10.129.10 3925 4034 6.8E-6 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.10.129.10 1879 2000 3.7E-9 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.50.980 168 319 6.0E-43 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1174 1190 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM01294 2867 2934 3.6E-6 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00550 Phosphopantetheine attachment site 2868 2934 8.9E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00550 Phosphopantetheine attachment site 4586 4649 4.4E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00550 Phosphopantetheine attachment site 947 993 4.6E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:1.10.1200.10 917 992 4.7E-11 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF53901 1018 1383 3.17E-98 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4608 4623 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2961 3211 3.0E-83 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1020 1261 7.8E-81 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:1.10.1200.10 2858 2961 2.0E-19 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1388 1475 1.6E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.50.720 2598 2843 2.8E-42 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.50.720 776 891 0.23 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00825 Beta-ketoacyl synthase 2963 3386 9.4E-202 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SMART SM00825 Beta-ketoacyl synthase 1022 1436 2.0E-203 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF47336 4572 4657 5.1E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.40.47.10 1274 1434 2.6E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Pfam PF13602 Zinc-binding dehydrogenase 2476 2595 1.6E-14 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF51735 4189 4328 9.84E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 Gene3D G3DSA:3.30.70.250 3706 3748 2.4E-13 T 28-03-2018 CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2893 2908 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS16265 ebe68bc22d9cf7a02c96dd61662a1902 4684 SUPERFAMILY SSF56801 8 500 3.01E-147 T 28-03-2018 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 379 2.5E-65 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 1 97 4.4E-41 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 SUPERFAMILY SSF55973 241 390 5.89E-65 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 SUPERFAMILY SSF55973 116 240 3.92E-45 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 122 132 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 Gene3D G3DSA:3.30.300.10 151 266 2.6E-40 T 28-03-2018 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 Gene3D G3DSA:3.30.300.10 7 143 9.1E-45 T 28-03-2018 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 1 390 2.0E-164 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 Gene3D G3DSA:3.30.300.10 267 393 2.2E-45 T 28-03-2018 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 391 54.496 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 Pfam PF02772 S-adenosylmethionine synthetase, central domain 120 239 1.5E-42 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 SUPERFAMILY SSF55973 1 105 1.41E-44 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15720 1efbafdad27483890b60a066e6f9f4ad 393 PIRSF PIRSF000497 1 392 5.7E-161 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS15535 90be860b4b4f4ecf149b316cd5351f13 120 Pfam PF02656 Domain of unknown function (DUF202) 20 84 6.5E-14 T 28-03-2018 IPR003807 Domain of unknown function DUF202 CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 Gene3D G3DSA:3.40.50.300 277 886 9.2E-35 T 28-03-2018 CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 SUPERFAMILY SSF52540 916 1123 2.66E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 SUPERFAMILY SSF52540 799 885 2.66E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 SUPERFAMILY SSF52540 284 410 2.66E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 Pfam PF13604 AAA domain 286 346 9.8E-9 T 28-03-2018 CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 SUPERFAMILY SSF52980 1143 1248 3.32E-14 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 Gene3D G3DSA:3.40.50.300 922 1121 4.0E-17 T 28-03-2018 CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 Pfam PF13087 AAA domain 916 1100 1.3E-13 T 28-03-2018 CNX65_RS23775 e44daa56ce251073e1ad7cf2987dbd67 1349 Gene3D G3DSA:3.40.960.10 1142 1261 1.1E-23 T 28-03-2018 CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 Gene3D G3DSA:2.80.10.50 2 119 2.6E-19 T 28-03-2018 CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 Gene3D G3DSA:2.160.20.10 226 430 1.9E-77 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 SMART SM00458 46 177 4.2E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 Pfam PF03211 Pectate lyase 215 405 1.7E-72 T 28-03-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 SUPERFAMILY SSF50370 43 177 1.17E-28 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 Pfam PF00652 Ricin-type beta-trefoil lectin domain 49 174 1.0E-18 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 Gene3D G3DSA:2.80.10.50 120 179 1.1E-15 T 28-03-2018 CNX65_RS20910 5a2448f4c0d0c80127b5cbe01a691b15 431 SUPERFAMILY SSF51126 219 395 4.28E-53 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS29380 8d7ecc2ccd599a519387f0490bc62ca4 291 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 215 1.7E-18 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS29380 8d7ecc2ccd599a519387f0490bc62ca4 291 Gene3D G3DSA:3.40.50.720 2 290 1.5E-42 T 28-03-2018 CNX65_RS29380 8d7ecc2ccd599a519387f0490bc62ca4 291 SUPERFAMILY SSF51735 3 275 2.93E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 Gene3D G3DSA:3.40.50.510 1 120 2.4E-29 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 Gene3D G3DSA:3.30.1340.10 142 227 6.2E-21 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 Pfam PF00381 PTS HPr component phosphorylation site 146 220 2.2E-19 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 Pfam PF03610 PTS system fructose IIA component 1 108 1.8E-19 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 146 219 4.6E-19 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 PRINTS PR00107 Phosphocarrier protein signature 193 210 8.9E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 PRINTS PR00107 Phosphocarrier protein signature 153 169 8.9E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 PRINTS PR00107 Phosphocarrier protein signature 178 193 8.9E-10 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 SUPERFAMILY SSF53062 1 115 6.28E-27 T 28-03-2018 IPR004701 Phosphotransferase system, mannose-type IIA component GO:0009401|GO:0016021 CNX65_RS30070 b2c69c48fdbbb079455de1a8bd34f9b7 227 SUPERFAMILY SSF55594 145 226 9.16E-20 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS18810 08059e20b03351d3172a51dcc6e3c48d 209 SUPERFAMILY SSF48498 76 196 1.18E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS18810 08059e20b03351d3172a51dcc6e3c48d 209 SUPERFAMILY SSF46689 6 66 2.72E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS18810 08059e20b03351d3172a51dcc6e3c48d 209 Gene3D G3DSA:1.10.10.60 2 59 1.4E-15 T 28-03-2018 CNX65_RS18810 08059e20b03351d3172a51dcc6e3c48d 209 Gene3D G3DSA:1.10.357.10 60 209 3.1E-11 T 28-03-2018 CNX65_RS18810 08059e20b03351d3172a51dcc6e3c48d 209 Pfam PF16859 Bacterial transcriptional repressor C-terminal 74 189 1.7E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS18810 08059e20b03351d3172a51dcc6e3c48d 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 6.9E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 SMART SM00895 88 212 1.1E-9 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 78 2.9E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 SMART SM00345 20 78 1.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 Gene3D G3DSA:1.20.120.530 81 222 5.6E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 Gene3D G3DSA:1.10.10.10 3 80 3.6E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 Pfam PF07729 FCD domain 88 210 1.8E-18 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 SUPERFAMILY SSF46785 15 82 2.27E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23495 55654a0338b3b2ec0e92137a1b496732 223 SUPERFAMILY SSF48008 84 217 4.71E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 Pfam PF00583 Acetyltransferase (GNAT) family 50 129 2.7E-5 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 Pfam PF00583 Acetyltransferase (GNAT) family 198 286 3.0E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 PIRSF PIRSF021524 1 297 4.5E-110 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 TIGRFAM TIGR03448 mycothiol_MshD: mycothiol synthase 5 295 2.8E-97 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 Hamap MF_01698 Mycothiol acetyltransferase [mshD]. 4 297 35.957 T 28-03-2018 IPR017813 Mycothiol acetyltransferase GO:0016747 CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 Gene3D G3DSA:3.40.630.30 153 297 3.2E-25 T 28-03-2018 CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 SUPERFAMILY SSF55729 6 294 1.24E-40 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS33735 b79ef493ed805176d3ac59150b44b4f5 297 Gene3D G3DSA:3.40.630.30 8 144 1.7E-13 T 28-03-2018 CNX65_RS31230 f6d3844c6a03a3e9965e86a8d668762e 330 Gene3D G3DSA:3.40.50.720 1 186 2.7E-44 T 28-03-2018 CNX65_RS31230 f6d3844c6a03a3e9965e86a8d668762e 330 Gene3D G3DSA:3.90.25.10 187 329 1.4E-51 T 28-03-2018 CNX65_RS31230 f6d3844c6a03a3e9965e86a8d668762e 330 SUPERFAMILY SSF51735 1 323 2.57E-102 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS31230 f6d3844c6a03a3e9965e86a8d668762e 330 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 307 1.3E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS31230 f6d3844c6a03a3e9965e86a8d668762e 330 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 322 4.7E-136 T 28-03-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 2 323 36.185 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 238 255 4.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 133 153 4.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 173 197 4.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 6 23 4.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 198 222 4.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 56 83 4.8E-45 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 SUPERFAMILY SSF48179 179 332 6.8E-51 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 PIRSF PIRSF000114 1 333 1.7E-98 T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 180 319 1.2E-48 T 28-03-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 Gene3D G3DSA:3.40.50.720 1 179 9.5E-44 T 28-03-2018 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 4 159 6.1E-50 T 28-03-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 SUPERFAMILY SSF51735 3 179 2.06E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 Gene3D G3DSA:1.10.1040.10 180 331 4.5E-50 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS29490 d856fa611ac21c9a1ff3b623d41249c1 333 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 188 209 - T 28-03-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|Reactome: R-HSA-1483166 CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 Pfam PF13530 Sterol carrier protein domain 183 398 9.3E-54 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 SUPERFAMILY SSF55729 4 297 1.8E-63 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 Hamap MF_01812 UPF0256 protein . 1 402 32.938 T 28-03-2018 IPR022902 N-acetyltransferase Eis CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 Gene3D G3DSA:3.30.1050.10 296 393 5.8E-31 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 Gene3D G3DSA:3.40.630.30 128 293 3.1E-48 T 28-03-2018 CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 Gene3D G3DSA:3.40.630.30 1 127 1.4E-15 T 28-03-2018 CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 Pfam PF13527 Acetyltransferase (GNAT) domain 3 130 3.9E-27 T 28-03-2018 CNX65_RS18065 e3e1d274e939aab663fadd5b2d362b28 402 SUPERFAMILY SSF55718 298 402 1.22E-24 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 1.5E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 SMART SM00354 8 78 2.3E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 Gene3D G3DSA:1.10.10.60 1 20 0.098 T 28-03-2018 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 28-03-2018 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 SUPERFAMILY SSF47413 9 66 1.1E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 Gene3D G3DSA:3.40.50.2300 181 319 3.4E-43 T 28-03-2018 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 Gene3D G3DSA:1.10.260.40 21 61 2.0E-22 T 28-03-2018 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 SUPERFAMILY SSF53822 67 336 1.32E-65 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 Pfam PF13377 Periplasmic binding protein-like domain 174 335 3.4E-36 T 28-03-2018 CNX65_RS14280 669068dfa2185be4815e4f6f0428715f 344 Gene3D G3DSA:3.40.50.2300 62 180 6.1E-31 T 28-03-2018 CNX65_RS09305 5cbd1153fec9c16d2170fdaa5e02af20 502 SUPERFAMILY SSF50443 329 497 3.14E-66 T 28-03-2018 IPR004216 L-fucose/L-arabinose isomerase, C-terminal CNX65_RS09305 5cbd1153fec9c16d2170fdaa5e02af20 502 ProDom PD018364 ISOMERASE L-ARABINOSE ARABINOSE METABOLISM CARBOHYDRATE CATABOLISM ARAA 8 304 3.0E-121 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CNX65_RS09305 5cbd1153fec9c16d2170fdaa5e02af20 502 Hamap MF_00519 L-arabinose isomerase [araA]. 1 476 62.329 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CNX65_RS09305 5cbd1153fec9c16d2170fdaa5e02af20 502 Pfam PF11762 L-arabinose isomerase C-terminal domain 363 475 1.3E-45 T 28-03-2018 IPR024664 L-arabinose isomerase, C-terminal KEGG: 00040+5.3.1.4 CNX65_RS09305 5cbd1153fec9c16d2170fdaa5e02af20 502 SUPERFAMILY SSF53743 5 325 6.54E-116 T 28-03-2018 IPR009015 L-fucose isomerase, N-terminal/central domain GO:0005737|GO:0005996|GO:0016861 CNX65_RS09305 5cbd1153fec9c16d2170fdaa5e02af20 502 Pfam PF02610 L-arabinose isomerase 7 359 1.7E-171 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CNX65_RS09305 5cbd1153fec9c16d2170fdaa5e02af20 502 PIRSF PIRSF001478 1 499 1.7E-226 T 28-03-2018 IPR003762 L-arabinose isomerase GO:0008152|GO:0008733 KEGG: 00040+5.3.1.4 CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 27 164 8.6E-9 T 28-03-2018 CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 SMART SM00387 24 180 1.2E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 SUPERFAMILY SSF54211 252 504 6.83E-93 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PIRSF PIRSF002583 1 646 9.3E-207 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PRINTS PR00775 90kDa heat shock protein signature 90 107 6.1E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PRINTS PR00775 90kDa heat shock protein signature 168 185 6.1E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PRINTS PR00775 90kDa heat shock protein signature 72 89 6.1E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PRINTS PR00775 90kDa heat shock protein signature 191 209 6.1E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PRINTS PR00775 90kDa heat shock protein signature 23 45 6.1E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PRINTS PR00775 90kDa heat shock protein signature 2 22 6.1E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 PRINTS PR00775 90kDa heat shock protein signature 118 140 6.1E-55 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 Hamap MF_00505 Chaperone protein HtpG [htpG]. 2 644 29.006 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 SUPERFAMILY SSF55874 2 211 2.41E-57 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 Gene3D G3DSA:3.30.565.10 1 227 2.8E-48 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 Pfam PF00183 Hsp90 protein 187 646 3.3E-134 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CNX65_RS12175 1c707a7d136fb98e255600f151a7bd60 647 SUPERFAMILY SSF110942 527 643 5.75E-30 T 28-03-2018 CNX65_RS02725 f4a1dfaea2cb5ce093c73af9ae19c95f 592 Gene3D G3DSA:1.10.287.1060 156 265 0.079 T 28-03-2018 CNX65_RS02725 f4a1dfaea2cb5ce093c73af9ae19c95f 592 SUPERFAMILY SSF140453 86 171 2.22E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS02725 f4a1dfaea2cb5ce093c73af9ae19c95f 592 Gene3D G3DSA:1.10.287.850 78 155 4.0E-8 T 28-03-2018 CNX65_RS09860 2e79d74d23c8db31cad0642872a2a442 650 Pfam PF07477 Glycosyl hydrolase family 67 C-terminus 426 647 9.6E-94 T 28-03-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 CNX65_RS09860 2e79d74d23c8db31cad0642872a2a442 650 SUPERFAMILY SSF51445 125 649 8.84E-215 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09860 2e79d74d23c8db31cad0642872a2a442 650 Gene3D G3DSA:3.20.20.80 123 446 3.9E-136 T 28-03-2018 CNX65_RS09860 2e79d74d23c8db31cad0642872a2a442 650 Pfam PF07488 Glycosyl hydrolase family 67 middle domain 118 424 4.9E-128 T 28-03-2018 IPR011100 Glycosyl hydrolase family 67, catalytic domain GO:0005576|GO:0045493|GO:0046559 CNX65_RS09860 2e79d74d23c8db31cad0642872a2a442 650 Gene3D G3DSA:3.90.1330.10 448 647 7.6E-85 T 28-03-2018 IPR011099 Glycosyl hydrolase family 67, C-terminal GO:0005576|GO:0045493|GO:0046559 CNX65_RS04210 ea694109cb2cd468405bba6e15d12a1d 109 Gene3D G3DSA:1.10.10.10 2 102 3.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04210 ea694109cb2cd468405bba6e15d12a1d 109 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 9 79 1.3E-15 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS04210 ea694109cb2cd468405bba6e15d12a1d 109 SUPERFAMILY SSF46767 4 76 3.53E-14 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS01385 098c2b5c4288f79051580f6afc5f63f0 261 Pfam PF04586 Caudovirus prohead serine protease 18 59 7.9E-5 T 28-03-2018 IPR006433 Prohead protease CNX65_RS01385 098c2b5c4288f79051580f6afc5f63f0 261 Gene3D G3DSA:3.20.16.10 8 211 1.0E-19 T 28-03-2018 IPR035443 Herpesvirus/Caudovirus protease domain CNX65_RS21565 10c0be8aec8df2eca1ee4af782e5de9c 447 Gene3D G3DSA:3.30.465.10 88 234 1.3E-40 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS21565 10c0be8aec8df2eca1ee4af782e5de9c 447 Pfam PF01565 FAD binding domain 36 174 9.7E-40 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS21565 10c0be8aec8df2eca1ee4af782e5de9c 447 Gene3D G3DSA:3.30.43.10 3 87 8.7E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS21565 10c0be8aec8df2eca1ee4af782e5de9c 447 Gene3D G3DSA:1.10.45.10 406 444 7.2E-16 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CNX65_RS21565 10c0be8aec8df2eca1ee4af782e5de9c 447 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 444 1.0E-57 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CNX65_RS21565 10c0be8aec8df2eca1ee4af782e5de9c 447 SUPERFAMILY SSF56176 13 212 1.64E-61 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS21565 10c0be8aec8df2eca1ee4af782e5de9c 447 SUPERFAMILY SSF55103 215 446 1.47E-54 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 Gene3D G3DSA:3.40.140.20 370 513 1.5E-48 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 Gene3D G3DSA:3.40.140.20 232 368 4.7E-48 T 28-03-2018 IPR024051 AICAR transformylase domain KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 10 523 41.624 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 SMART SM00798 141 458 3.4E-177 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 SUPERFAMILY SSF53927 216 523 9.13E-113 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 SUPERFAMILY SSF52335 10 197 1.22E-63 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 11 523 3.5E-167 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 PIRSF PIRSF000414 5 523 1.2E-190 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 Pfam PF02142 MGS-like domain 22 135 6.0E-25 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 Gene3D G3DSA:3.40.50.1380 1 198 7.8E-69 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 SMART SM00851 22 136 2.7E-49 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS31910 17965295de58be20cb7f0a3245d313d7 523 Pfam PF01808 AICARFT/IMPCHase bienzyme 142 457 2.9E-111 T 28-03-2018 IPR002695 AICARFT/IMPCHase bienzyme GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS19210 1dd6432dad137c56ed7ee0d033c4a609 1081 Gene3D G3DSA:2.70.98.10 33 362 3.8E-96 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS19210 1dd6432dad137c56ed7ee0d033c4a609 1081 Gene3D G3DSA:1.20.1610.10 493 647 1.5E-46 T 28-03-2018 CNX65_RS19210 1dd6432dad137c56ed7ee0d033c4a609 1081 SUPERFAMILY SSF48208 304 755 8.16E-22 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS19210 1dd6432dad137c56ed7ee0d033c4a609 1081 Gene3D G3DSA:1.20.1050.60 387 482 1.1E-16 T 28-03-2018 CNX65_RS19210 1dd6432dad137c56ed7ee0d033c4a609 1081 Pfam PF07971 Glycosyl hydrolase family 92 281 778 2.2E-153 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CNX65_RS19210 1dd6432dad137c56ed7ee0d033c4a609 1081 Gene3D G3DSA:3.30.2080.10 648 791 1.4E-53 T 28-03-2018 CNX65_RS19210 1dd6432dad137c56ed7ee0d033c4a609 1081 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 20 781 1.6E-149 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CNX65_RS05880 5db300f73dbe1ce06341dbb894c8e24f 392 Gene3D G3DSA:3.10.560.10 217 264 4.8E-4 T 28-03-2018 CNX65_RS05880 5db300f73dbe1ce06341dbb894c8e24f 392 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 298 383 2.5E-10 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS05880 5db300f73dbe1ce06341dbb894c8e24f 392 SUPERFAMILY SSF140490 292 388 1.44E-11 T 28-03-2018 CNX65_RS05880 5db300f73dbe1ce06341dbb894c8e24f 392 Pfam PF10531 SLBB domain 224 260 1.6E-8 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS05880 5db300f73dbe1ce06341dbb894c8e24f 392 SUPERFAMILY SSF142019 47 221 1.24E-35 T 28-03-2018 CNX65_RS05880 5db300f73dbe1ce06341dbb894c8e24f 392 SUPERFAMILY SSF142984 223 276 4.97E-9 T 28-03-2018 CNX65_RS05880 5db300f73dbe1ce06341dbb894c8e24f 392 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 62 207 4.1E-29 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS13490 eeac43134c09c1b790a45f6f0eea39e9 413 Pfam PF13535 ATP-grasp domain 141 294 2.3E-18 T 28-03-2018 CNX65_RS13490 eeac43134c09c1b790a45f6f0eea39e9 413 Gene3D G3DSA:3.40.50.20 17 110 3.2E-4 T 28-03-2018 CNX65_RS13490 eeac43134c09c1b790a45f6f0eea39e9 413 SUPERFAMILY SSF56059 85 334 1.29E-35 T 28-03-2018 CNX65_RS13490 eeac43134c09c1b790a45f6f0eea39e9 413 Gene3D G3DSA:3.30.470.20 111 408 3.5E-36 T 28-03-2018 CNX65_RS31395 6796c83a299f6cd68eb8f4058435cc93 206 Pfam PF02545 Maf-like protein 2 192 1.0E-41 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CNX65_RS31395 6796c83a299f6cd68eb8f4058435cc93 206 Hamap MF_00528 Septum formation protein Maf [maf]. 2 197 24.316 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CNX65_RS31395 6796c83a299f6cd68eb8f4058435cc93 206 TIGRFAM TIGR00172 maf: septum formation protein Maf 3 191 1.6E-44 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CNX65_RS31395 6796c83a299f6cd68eb8f4058435cc93 206 Gene3D G3DSA:3.90.950.10 1 200 7.2E-56 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CNX65_RS31395 6796c83a299f6cd68eb8f4058435cc93 206 PIRSF PIRSF006305 1 199 1.3E-35 T 28-03-2018 IPR003697 Maf-like protein GO:0047429 CNX65_RS31395 6796c83a299f6cd68eb8f4058435cc93 206 SUPERFAMILY SSF52972 2 192 8.5E-45 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CNX65_RS18535 4206616c5822823c96f303d58ad6dcfc 186 SUPERFAMILY SSF46689 10 73 7.48E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS18535 4206616c5822823c96f303d58ad6dcfc 186 Gene3D G3DSA:1.10.10.60 9 52 9.9E-15 T 28-03-2018 CNX65_RS18535 4206616c5822823c96f303d58ad6dcfc 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18535 4206616c5822823c96f303d58ad6dcfc 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18535 4206616c5822823c96f303d58ad6dcfc 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 2.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18535 4206616c5822823c96f303d58ad6dcfc 186 Gene3D G3DSA:1.10.357.10 53 186 5.1E-17 T 28-03-2018 CNX65_RS18535 4206616c5822823c96f303d58ad6dcfc 186 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 Pfam PF13575 Domain of unknown function (DUF4135) 148 512 1.6E-109 T 28-03-2018 IPR025410 Lantibiotic biosynthesis protein, dehydration domain CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 TIGRFAM TIGR03897 lanti_2_LanM: type 2 lantibiotic biosynthesis protein LanM 85 721 5.2E-153 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 SMART SM01260 635 1018 3.7E-48 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PRINTS PR01955 Frankia sp. LanC-like protein signature 639 654 5.8E-6 T 28-03-2018 CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PRINTS PR01955 Frankia sp. LanC-like protein signature 935 955 5.8E-6 T 28-03-2018 CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PRINTS PR01955 Frankia sp. LanC-like protein signature 991 1008 5.8E-6 T 28-03-2018 CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 Gene3D G3DSA:1.50.10.10 691 918 0.031 T 28-03-2018 CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 Pfam PF05147 Lanthionine synthetase C-like protein 842 1018 5.5E-17 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PIRSF PIRSF037228 799 1021 7.9E-24 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PIRSF PIRSF037228 72 726 1.5E-117 T 28-03-2018 IPR017146 Type 2 lantibiotic biosynthesis protein LanM CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 SUPERFAMILY SSF158745 617 718 3.14E-14 T 28-03-2018 CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PRINTS PR01950 LanC-like protein superfamily signature 638 656 1.8E-6 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PRINTS PR01950 LanC-like protein superfamily signature 990 1007 1.8E-6 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PRINTS PR01950 LanC-like protein superfamily signature 840 856 1.8E-6 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 PRINTS PR01950 LanC-like protein superfamily signature 936 949 1.8E-6 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CNX65_RS26450 dafc95ff4e18e1cccf92819cf7dfa73b 1022 SUPERFAMILY SSF158745 798 1020 2.48E-18 T 28-03-2018 CNX65_RS01280 3d80b331c2922b337f2e01c45d871d49 694 SUPERFAMILY SSF56601 223 563 4.32E-81 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS01280 3d80b331c2922b337f2e01c45d871d49 694 Pfam PF00144 Beta-lactamase 224 556 9.7E-69 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS01280 3d80b331c2922b337f2e01c45d871d49 694 Gene3D G3DSA:3.40.710.10 217 567 1.4E-87 T 28-03-2018 CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 66 1.1E-30 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 SUPERFAMILY SSF50249 2 66 5.14E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 PRINTS PR00050 Cold shock protein signature 4 19 3.0E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 PRINTS PR00050 Cold shock protein signature 40 58 3.0E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 PRINTS PR00050 Cold shock protein signature 25 34 3.0E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 Gene3D G3DSA:2.40.50.140 1 67 3.3E-28 T 28-03-2018 CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 SMART SM00357 3 67 9.5E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CNX65_RS01030 41efd9a34c13df3364274f042d56dfb5 67 PIRSF PIRSF002599 1 67 9.8E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CNX65_RS30085 470ce3ebc29f7987a2ff228ba43c5dfa 501 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS30085 470ce3ebc29f7987a2ff228ba43c5dfa 501 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS30085 470ce3ebc29f7987a2ff228ba43c5dfa 501 PIRSF PIRSF036492 24 499 7.8E-90 T 28-03-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0004030|GO:0006081|GO:0055114 CNX65_RS30085 470ce3ebc29f7987a2ff228ba43c5dfa 501 Gene3D G3DSA:3.40.605.10 7 265 2.4E-84 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS30085 470ce3ebc29f7987a2ff228ba43c5dfa 501 SUPERFAMILY SSF53720 14 468 3.27E-132 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS30085 470ce3ebc29f7987a2ff228ba43c5dfa 501 Pfam PF00171 Aldehyde dehydrogenase family 19 466 1.7E-129 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS30085 470ce3ebc29f7987a2ff228ba43c5dfa 501 Gene3D G3DSA:3.40.309.10 266 447 1.3E-55 T 28-03-2018 CNX65_RS16505 addbb56092a2ca974dcb7e7615f4605b 179 Pfam PF10517 Electron transfer DM13 76 177 3.0E-28 T 28-03-2018 IPR019545 DM13 domain CNX65_RS00535 a2a584ed2982d1496ac31599bd711bbc 297 Pfam PF13560 Helix-turn-helix domain 22 82 2.5E-13 T 28-03-2018 CNX65_RS00535 a2a584ed2982d1496ac31599bd711bbc 297 Gene3D G3DSA:1.10.10.60 21 47 2.8E-8 T 28-03-2018 CNX65_RS00535 a2a584ed2982d1496ac31599bd711bbc 297 SMART SM00530 25 80 2.1E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS00535 a2a584ed2982d1496ac31599bd711bbc 297 Gene3D G3DSA:1.10.260.40 48 80 5.6E-4 T 28-03-2018 CNX65_RS00535 a2a584ed2982d1496ac31599bd711bbc 297 SUPERFAMILY SSF47413 19 79 7.51E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 SUPERFAMILY SSF52540 361 603 1.33E-88 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 SUPERFAMILY SSF90123 22 352 6.93E-86 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 Pfam PF00005 ABC transporter 384 532 7.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 Gene3D G3DSA:3.40.50.300 354 608 4.0E-75 T 28-03-2018 CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 SMART SM00382 392 578 3.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 Pfam PF00664 ABC transporter transmembrane region 40 321 2.6E-58 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 Gene3D G3DSA:1.20.1560.10 14 353 8.8E-91 T 28-03-2018 CNX65_RS18800 ee3061742c4c28091d8a5c64bfaab268 613 ProSitePatterns PS00211 ABC transporters family signature. 504 518 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS30420 1abd31f155da5e8d9d5ba828b902658c 326 Gene3D G3DSA:3.20.20.100 15 326 7.1E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS30420 1abd31f155da5e8d9d5ba828b902658c 326 Pfam PF00248 Aldo/keto reductase family 28 325 8.4E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS30420 1abd31f155da5e8d9d5ba828b902658c 326 SUPERFAMILY SSF51430 13 324 9.17E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS28805 729fd580d7d838567052d9435e4f0b64 299 SUPERFAMILY SSF53474 15 295 1.69E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS28805 729fd580d7d838567052d9435e4f0b64 299 Pfam PF12146 Serine aminopeptidase, S33 20 275 1.1E-24 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CNX65_RS28805 729fd580d7d838567052d9435e4f0b64 299 Gene3D G3DSA:3.40.50.1820 5 299 1.2E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00385 P450 superfamily signature 267 278 1.5E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00385 P450 superfamily signature 232 249 1.5E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00385 P450 superfamily signature 344 355 1.5E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00385 P450 superfamily signature 335 344 1.5E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 84 95 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 131 147 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 344 355 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 286 313 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 186 208 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 267 278 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 335 344 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 148 163 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 PRINTS PR00359 B-class P450 signature 314 329 4.5E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 Pfam PF00067 Cytochrome P450 268 364 1.5E-19 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 Pfam PF00067 Cytochrome P450 179 259 4.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 SUPERFAMILY SSF48264 13 395 2.23E-96 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 Gene3D G3DSA:1.10.630.10 4 395 8.2E-78 T 28-03-2018 CNX65_RS15360 4eb08e0ee1c6b435519e84ec362529ae 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 450 477 2.0E-7 T 28-03-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Gene3D G3DSA:2.40.50.140 364 431 9.5E-29 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 SMART SM00532 45 491 1.3E-256 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Pfam PF12826 Helix-hairpin-helix motif 559 622 4.7E-15 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 SUPERFAMILY SSF50249 359 442 1.88E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Gene3D G3DSA:1.10.150.20 475 554 1.8E-20 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Gene3D G3DSA:3.40.50.10190 622 718 3.3E-14 T 28-03-2018 IPR001357 BRCT domain CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Gene3D G3DSA:3.30.1490.70 284 363 5.7E-28 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 644 710 1.4E-9 T 28-03-2018 IPR001357 BRCT domain CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 SUPERFAMILY SSF47781 445 632 2.78E-44 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 373 388 - T 28-03-2018 IPR033136 NAD-dependent DNA ligase, conserved site CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 SUPERFAMILY SSF56091 44 358 1.24E-111 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Gene3D G3DSA:1.10.287.610 37 108 1.2E-26 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 53 710 5.9E-230 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Hamap MF_01588 DNA ligase [ligA]. 44 715 48.628 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 SMART SM00292 641 718 2.7E-10 T 28-03-2018 IPR001357 BRCT domain CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 363 440 1.1E-30 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Gene3D G3DSA:3.30.470.30 159 283 3.2E-47 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Gene3D G3DSA:1.10.150.20 555 621 1.2E-21 T 28-03-2018 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 SUPERFAMILY SSF52113 644 717 7.29E-14 T 28-03-2018 IPR001357 BRCT domain CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 PIRSF PIRSF001604 40 719 3.5E-226 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 155 184 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CNX65_RS29700 d08cef3987f2dd583ff0f929bbdf7505 801 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 46 360 7.7E-119 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 Gene3D G3DSA:3.30.565.10 307 455 4.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 1.0E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 1.0E-7 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 SMART SM00387 344 453 4.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 SUPERFAMILY SSF158472 185 231 6.54E-8 T 28-03-2018 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 SMART SM00388 239 304 3.1E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 Gene3D G3DSA:1.10.287.130 229 300 3.0E-9 T 28-03-2018 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 SUPERFAMILY SSF47384 222 303 7.46E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 SUPERFAMILY SSF55874 308 449 2.62E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 450 3.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 Pfam PF00512 His Kinase A (phospho-acceptor) domain 240 303 1.2E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 Pfam PF00672 HAMP domain 185 231 7.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS27920 3ec50336df9806e814d86e915d598dcb 455 SMART SM00304 185 238 1.3E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 Gene3D G3DSA:3.40.640.10 193 319 2.8E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 PIRSF PIRSF000521 191 429 1.8E-42 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 PIRSF PIRSF000521 143 179 0.0065 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 PIRSF PIRSF000521 1 151 4.1E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 Pfam PF00202 Aminotransferase class-III 44 425 1.0E-117 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 32 427 37.277 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 Gene3D G3DSA:3.90.1150.10 320 430 2.3E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 Gene3D G3DSA:3.90.1150.10 16 186 7.8E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 250 287 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15625 1f8831180e39ad9f5ec51eec6b5d2085 431 SUPERFAMILY SSF53383 37 426 1.99E-132 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 Gene3D G3DSA:3.50.50.60 154 301 9.1E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 13 204 8.2E-30 T 28-03-2018 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 Gene3D G3DSA:3.50.50.60 302 348 0.083 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 8.6E-6 T 28-03-2018 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 8.6E-6 T 28-03-2018 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 Gene3D G3DSA:3.50.50.60 7 153 6.4E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 SUPERFAMILY SSF51905 13 201 4.66E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 1.8E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 135 1.8E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 166 190 1.8E-9 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS19570 bfee9275c04c5b8e851f68fc9fd3e7e7 392 SUPERFAMILY SSF51905 138 377 5.18E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 5 487 33.307 T 28-03-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 SMART SM00382 99 303 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Gene3D G3DSA:1.20.120.140 1 91 1.2E-28 T 28-03-2018 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Gene3D G3DSA:1.10.260.30 329 432 2.9E-33 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Pfam PF00448 SRP54-type protein, GTPase domain 100 298 2.4E-69 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 SUPERFAMILY SSF52540 42 356 4.45E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 271 284 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 TIGRFAM TIGR00959 ffh: signal recognition particle protein 2 428 5.0E-178 T 28-03-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 SMART SM00963 1 86 1.6E-33 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Pfam PF02881 SRP54-type protein, helical bundle domain 5 82 7.1E-21 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Gene3D G3DSA:1.20.120.140 213 312 1.7E-31 T 28-03-2018 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 SUPERFAMILY SSF47446 329 430 4.58E-32 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 SMART SM00962 100 298 2.2E-108 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Pfam PF02978 Signal peptide binding domain 330 427 1.2E-28 T 28-03-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 CNX65_RS29110 da8046841e4367ae1e8384ec8ac4b4c7 518 Gene3D G3DSA:3.40.50.300 99 212 1.7E-17 T 28-03-2018 CNX65_RS05340 ce261fd5b54a7c632a34b5f327f8e2fa 475 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 4 86 1.8E-29 T 28-03-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202|KEGG: 00230+2.7.1.20|MetaCyc: PWY-6619 CNX65_RS05340 ce261fd5b54a7c632a34b5f327f8e2fa 475 Gene3D G3DSA:3.40.50.2300 2 100 5.8E-36 T 28-03-2018 CNX65_RS05340 ce261fd5b54a7c632a34b5f327f8e2fa 475 SUPERFAMILY SSF52794 3 98 4.19E-30 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CNX65_RS05340 ce261fd5b54a7c632a34b5f327f8e2fa 475 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 5 91 8.0E-19 T 28-03-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 CNX65_RS05340 ce261fd5b54a7c632a34b5f327f8e2fa 475 Pfam PF02378 Phosphotransferase system, EIIC 136 411 1.7E-8 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CNX65_RS05340 ce261fd5b54a7c632a34b5f327f8e2fa 475 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 128 465 4.5E-105 T 28-03-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Gene3D G3DSA:3.90.600.10 322 412 2.7E-29 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 281 288 - T 28-03-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 SMART SM01209 101 287 3.3E-108 T 28-03-2018 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 323 409 3.6E-27 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 SMART SM01210 322 411 6.4E-40 T 28-03-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 411 39.221 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Gene3D G3DSA:3.30.1490.20 86 181 3.3E-20 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 2 100 3.7E-29 T 28-03-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 SUPERFAMILY SSF56059 102 310 2.42E-52 T 28-03-2018 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 SUPERFAMILY SSF52440 2 101 5.61E-30 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 SUPERFAMILY SSF51246 320 411 1.18E-24 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Gene3D G3DSA:3.40.50.20 2 85 2.4E-31 T 28-03-2018 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Gene3D G3DSA:3.30.470.20 183 320 3.5E-57 T 28-03-2018 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 2 411 2.8E-144 T 28-03-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS34110 d33aabdb7994a76d0c9a7ad69c03f079 419 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 287 2.5E-67 T 28-03-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 Pfam PF01494 FAD binding domain 2 334 5.1E-80 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 Gene3D G3DSA:3.50.50.60 2 150 4.8E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 Gene3D G3DSA:3.30.9.10 278 362 2.2E-17 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 Gene3D G3DSA:3.30.9.10 151 277 3.3E-19 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 Gene3D G3DSA:3.40.30.20 411 477 1.8E-11 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 SUPERFAMILY SSF51905 2 167 4.36E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 SUPERFAMILY SSF51905 257 351 4.36E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 7.1E-36 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 7.1E-36 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 7.1E-36 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 7.1E-36 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 7.1E-36 T 28-03-2018 CNX65_RS23840 49a0e0873b8cb0e80bb0d4b8b7accf91 477 SUPERFAMILY SSF52833 379 474 4.7E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 Gene3D G3DSA:3.40.190.10 180 263 1.4E-11 T 28-03-2018 CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 Pfam PF03466 LysR substrate binding domain 87 293 6.9E-28 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.5E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 SUPERFAMILY SSF46785 3 82 5.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 Gene3D G3DSA:1.10.10.10 1 83 4.6E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 SUPERFAMILY SSF53850 88 296 2.26E-28 T 28-03-2018 CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 7.3E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24355 d207478ab57d2df23b7f66b4357148ec 306 Gene3D G3DSA:3.40.190.10 88 179 6.5E-20 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF51735 1706 1817 1.09E-6 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF51735 2893 3055 3.15E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:1.10.1200.10 1904 2005 9.3E-21 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2189 2205 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.50.720 3049 3294 1.0E-41 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF08659 KR domain 3068 3246 3.5E-50 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3068 3248 1.9E-44 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF55048 1220 1279 4.45E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1096 1388 9.6E-89 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2547 2854 1.2E-87 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 397 583 1.2E-13 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF51735 1511 1697 5.12E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF52151 394 574 3.14E-30 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF52151 2544 2671 6.54E-58 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF52151 2732 2828 6.54E-58 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF53901 31 261 4.94E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF52151 1092 1221 2.88E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF52151 1280 1379 2.88E-57 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00823 Phosphopantetheine attachment site 1897 1969 1.1E-26 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00825 Beta-ketoacyl synthase 645 992 3.2E-67 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00825 Beta-ketoacyl synthase 2035 2447 3.6E-139 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM00825 Beta-ketoacyl synthase 36 270 1.0E-19 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SMART SM01294 1898 1965 2.0E-5 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.366.10 1273 1395 8.4E-28 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.30.70.250 1227 1272 1.6E-13 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.30.70.250 2677 2722 6.5E-14 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.366.10 2723 2848 4.6E-21 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.47.10 2287 2445 5.4E-47 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF00698 Acyl transferase domain 2546 2858 7.7E-47 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF00698 Acyl transferase domain 1094 1407 2.4E-70 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF00698 Acyl transferase domain 395 514 4.4E-29 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.47.10 171 232 8.9E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.47.10 35 170 2.9E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF55048 2670 2729 1.09E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.47.10 2036 2285 8.2E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF51735 3064 3277 6.04E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF53901 2172 2386 6.3E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF53901 2031 2144 6.3E-79 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF00550 Phosphopantetheine attachment site 1899 1965 7.9E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2392 2510 2.4E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.47.10 645 846 2.9E-49 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 857 942 3.3E-12 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2280 2387 6.5E-32 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.50.720 1671 1903 7.3E-6 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.366.10 383 533 1.3E-34 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 55 171 7.0E-27 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2033 2272 1.1E-62 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 643 814 5.4E-41 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.366.10 534 597 1.5E-5 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF53901 640 942 1.34E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Pfam PF08990 Erythronolide synthase docking 3 25 1.8E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 SUPERFAMILY SSF47336 1890 1978 3.93E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.47.10 854 994 4.0E-21 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.366.10 1092 1226 1.6E-32 T 28-03-2018 CNX65_RS21810 8ff2497408a7b6941e3528034665e73a 3365 Gene3D G3DSA:3.40.366.10 2543 2676 1.5E-37 T 28-03-2018 CNX65_RS21080 54b059580fa54f8751a8d1f338cdc5ae 542 Pfam PF00501 AMP-binding enzyme 35 428 8.9E-59 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS21080 54b059580fa54f8751a8d1f338cdc5ae 542 Gene3D G3DSA:3.30.300.30 432 514 1.9E-6 T 28-03-2018 CNX65_RS21080 54b059580fa54f8751a8d1f338cdc5ae 542 SUPERFAMILY SSF56801 21 503 1.28E-86 T 28-03-2018 CNX65_RS21080 54b059580fa54f8751a8d1f338cdc5ae 542 Gene3D G3DSA:3.40.50.980 24 175 3.6E-26 T 28-03-2018 CNX65_RS21080 54b059580fa54f8751a8d1f338cdc5ae 542 Gene3D G3DSA:3.40.50.980 176 335 6.9E-23 T 28-03-2018 CNX65_RS21080 54b059580fa54f8751a8d1f338cdc5ae 542 Gene3D G3DSA:2.30.38.10 349 424 5.5E-21 T 28-03-2018 CNX65_RS10100 f758aa0d315dd0e0864e6fc75ddcb436 409 Gene3D G3DSA:1.10.150.130 62 209 3.3E-14 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS10100 f758aa0d315dd0e0864e6fc75ddcb436 409 Gene3D G3DSA:1.10.443.10 210 401 2.3E-36 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS10100 f758aa0d315dd0e0864e6fc75ddcb436 409 SUPERFAMILY SSF56349 69 125 4.12E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS10100 f758aa0d315dd0e0864e6fc75ddcb436 409 SUPERFAMILY SSF56349 153 401 4.12E-48 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS10100 f758aa0d315dd0e0864e6fc75ddcb436 409 Pfam PF00589 Phage integrase family 231 393 4.7E-14 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS10100 f758aa0d315dd0e0864e6fc75ddcb436 409 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 72 123 6.4E-5 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 Pfam PF02867 Ribonucleotide reductase, barrel domain 348 881 9.9E-173 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 SUPERFAMILY SSF48168 132 346 4.45E-62 T 28-03-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 Gene3D G3DSA:3.20.70.20 253 889 3.3E-207 T 28-03-2018 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 271 344 3.7E-23 T 28-03-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 726 747 - T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 275 884 3.7E-205 T 28-03-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 Pfam PF03477 ATP cone domain 16 112 1.7E-14 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 Pfam PF03477 ATP cone domain 127 211 4.9E-7 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 PRINTS PR01183 Ribonucleotide reductase large chain signature 736 763 1.5E-44 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 PRINTS PR01183 Ribonucleotide reductase large chain signature 595 618 1.5E-44 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 PRINTS PR01183 Ribonucleotide reductase large chain signature 558 569 1.5E-44 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 PRINTS PR01183 Ribonucleotide reductase large chain signature 423 442 1.5E-44 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 PRINTS PR01183 Ribonucleotide reductase large chain signature 633 655 1.5E-44 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 PRINTS PR01183 Ribonucleotide reductase large chain signature 661 684 1.5E-44 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 SUPERFAMILY SSF51998 347 785 2.41E-171 T 28-03-2018 CNX65_RS16050 b37a5fc48f8da30666aa060f15dc4cf9 939 SUPERFAMILY SSF51998 816 884 2.41E-171 T 28-03-2018 CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 SUPERFAMILY SSF54999 5 100 9.02E-37 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 101 24.573 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 SMART SM01403 7 101 1.5E-55 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 4.8E-46 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 Gene3D G3DSA:3.30.70.600 4 101 3.3E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 3.7E-21 T 28-03-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 Pfam PF00338 Ribosomal protein S10p/S20e 7 100 9.6E-35 T 28-03-2018 IPR027486 Ribosomal protein S10 domain CNX65_RS32455 e9f3a1c5044ed9a01a83e8f98eea5fbd 101 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 28-03-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS12305 ce7e83f593812365c1730a4f9dc895da 207 Gene3D G3DSA:1.10.357.10 75 205 7.5E-5 T 28-03-2018 CNX65_RS12305 ce7e83f593812365c1730a4f9dc895da 207 SUPERFAMILY SSF46689 7 87 2.31E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12305 ce7e83f593812365c1730a4f9dc895da 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 22 64 3.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12305 ce7e83f593812365c1730a4f9dc895da 207 Gene3D G3DSA:1.10.10.60 1 52 1.8E-10 T 28-03-2018 CNX65_RS12305 ce7e83f593812365c1730a4f9dc895da 207 Gene3D G3DSA:1.10.10.60 53 74 1.1E-6 T 28-03-2018 CNX65_RS21350 3b11b72ef781eb6835465b5dc7dba0b2 429 SUPERFAMILY SSF55874 312 428 5.07E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS21350 3b11b72ef781eb6835465b5dc7dba0b2 429 Pfam PF07730 Histidine kinase 232 296 5.7E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS21350 3b11b72ef781eb6835465b5dc7dba0b2 429 Gene3D G3DSA:3.30.565.10 303 429 6.9E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 Pfam PF03129 Anticodon binding domain 488 575 2.3E-16 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 Gene3D G3DSA:3.30.930.10 13 472 2.8E-89 T 28-03-2018 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 SUPERFAMILY SSF52954 476 578 7.36E-27 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 SUPERFAMILY SSF55826 221 399 3.14E-11 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 4 574 3.3E-169 T 28-03-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 96 470 9.5E-37 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 Pfam PF04073 Aminoacyl-tRNA editing domain 259 384 1.1E-22 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 Gene3D G3DSA:3.40.50.800 473 580 3.8E-28 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 SUPERFAMILY SSF55681 419 490 3.45E-89 T 28-03-2018 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 SUPERFAMILY SSF55681 12 239 3.45E-89 T 28-03-2018 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 Hamap MF_01569 Proline--tRNA ligase [proS]. 3 580 36.497 T 28-03-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 146 157 1.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 136 144 1.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 70 88 1.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CNX65_RS28680 b658107d72af8eb10e3c16c5ada3a841 581 PRINTS PR01046 Prolyl-tRNA synthetase signature 106 117 1.5E-14 T 28-03-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 CNX65_RS16035 d1dc307f5108a2300b072a373a9acc31 222 Gene3D G3DSA:1.10.357.10 11 222 5.1E-24 T 28-03-2018 CNX65_RS16035 d1dc307f5108a2300b072a373a9acc31 222 SUPERFAMILY SSF46689 7 81 5.13E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16035 d1dc307f5108a2300b072a373a9acc31 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 7.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 SMART SM00958 225 337 1.1E-62 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Gene3D G3DSA:1.10.3060.10 642 828 4.6E-61 T 28-03-2018 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 SUPERFAMILY SSF52540 395 612 3.44E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Pfam PF01043 SecA preprotein cross-linking domain 229 337 1.5E-35 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Gene3D G3DSA:3.40.50.300 6 270 2.6E-53 T 28-03-2018 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Gene3D G3DSA:3.40.50.300 287 395 3.4E-8 T 28-03-2018 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Pfam PF07517 SecA DEAD-like domain 6 380 2.6E-128 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 SUPERFAMILY SSF81886 614 834 3.14E-73 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Hamap MF_01382 Protein translocase subunit SecA [secA]. 2 829 19.921 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 ProSitePatterns PS01312 SecA family signature. 479 494 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 PRINTS PR00906 SecA protein signature 98 112 1.5E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 PRINTS PR00906 SecA protein signature 392 405 1.5E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 PRINTS PR00906 SecA protein signature 60 84 1.5E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 PRINTS PR00906 SecA protein signature 355 372 1.5E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 PRINTS PR00906 SecA protein signature 318 340 1.5E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 PRINTS PR00906 SecA protein signature 114 124 1.5E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 PRINTS PR00906 SecA protein signature 167 187 1.5E-70 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Pfam PF07516 SecA Wing and Scaffold domain 611 826 1.6E-68 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 SUPERFAMILY SSF52540 347 394 4.15E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 SUPERFAMILY SSF52540 8 225 4.15E-78 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 25 814 0.0 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 SUPERFAMILY SSF81767 224 347 1.57E-43 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 Gene3D G3DSA:3.40.50.300 396 641 3.5E-56 T 28-03-2018 CNX65_RS31060 224359de7f541ed41b8eef5a7f3ad30e 975 SMART SM00957 3 381 3.7E-277 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 Gene3D G3DSA:1.25.40.10 517 866 1.4E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 Pfam PF00196 Bacterial regulatory proteins, luxR family 885 935 3.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 Gene3D G3DSA:1.25.40.10 354 478 0.25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 Gene3D G3DSA:1.10.10.10 867 942 7.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 Pfam PF13191 AAA ATPase domain 5 153 4.3E-21 T 28-03-2018 CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 SUPERFAMILY SSF52540 3 223 3.92E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 Gene3D G3DSA:3.40.50.300 2 167 5.6E-11 T 28-03-2018 CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 SUPERFAMILY SSF46894 872 936 3.4E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS17900 41ddb82b2dc1f0f5878ed7f807f9e87b 987 SMART SM00421 882 939 6.7E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS19020 a85fe401e0d057a96f842b2368d313dd 285 PIRSF PIRSF000103 1 285 3.8E-69 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CNX65_RS19020 a85fe401e0d057a96f842b2368d313dd 285 SUPERFAMILY SSF51735 4 161 7.48E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19020 a85fe401e0d057a96f842b2368d313dd 285 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 166 283 2.0E-14 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CNX65_RS19020 a85fe401e0d057a96f842b2368d313dd 285 Gene3D G3DSA:1.10.1040.10 162 285 2.0E-18 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS19020 a85fe401e0d057a96f842b2368d313dd 285 Gene3D G3DSA:3.40.50.720 1 160 3.8E-29 T 28-03-2018 CNX65_RS19020 a85fe401e0d057a96f842b2368d313dd 285 SUPERFAMILY SSF48179 165 284 4.53E-21 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS19020 a85fe401e0d057a96f842b2368d313dd 285 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 160 1.7E-36 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 Gene3D G3DSA:3.20.20.140 47 390 1.1E-76 T 28-03-2018 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 34 398 2.1E-95 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 ProSitePatterns PS00483 Dihydroorotase signature 2. 281 292 - T 28-03-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 Gene3D G3DSA:2.30.40.10 5 46 0.021 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 SUPERFAMILY SSF51556 44 341 1.87E-76 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 SUPERFAMILY SSF51338 30 42 1.42E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 SUPERFAMILY SSF51338 343 399 1.42E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 Hamap MF_00220_B Dihydroorotase [pyrC]. 1 401 33.647 T 28-03-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS24160 894efdc4b82bc0187ab44a5563c19dee 451 Pfam PF01979 Amidohydrolase family 118 396 1.1E-11 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS04605 e97b8c3a92680ab7ab15666550fc3c0f 386 Pfam PF13180 PDZ domain 181 248 2.3E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS04605 e97b8c3a92680ab7ab15666550fc3c0f 386 SUPERFAMILY SSF54211 269 374 7.59E-21 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS04605 e97b8c3a92680ab7ab15666550fc3c0f 386 SUPERFAMILY SSF50156 180 283 8.94E-20 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS04605 e97b8c3a92680ab7ab15666550fc3c0f 386 SMART SM00228 165 239 2.3E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS04605 e97b8c3a92680ab7ab15666550fc3c0f 386 Gene3D G3DSA:3.30.230.10 87 384 2.4E-41 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS04605 e97b8c3a92680ab7ab15666550fc3c0f 386 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 282 370 1.3E-10 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 161 333 1.5E-7 T 28-03-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0003942|GO:0005737|GO:0008652|GO:0016620|GO:0046983|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 SUPERFAMILY SSF51735 7 175 2.01E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 Gene3D G3DSA:3.30.360.10 162 330 5.0E-37 T 28-03-2018 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 6 356 32.444 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 143 9.0E-20 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 Gene3D G3DSA:3.40.50.720 1 161 9.7E-34 T 28-03-2018 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 SMART SM00859 7 144 1.5E-34 T 28-03-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 SUPERFAMILY SSF55347 152 330 2.83E-34 T 28-03-2018 CNX65_RS16885 db952aefcb5f022a5ff758bd73b81fee 360 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 7 356 3.4E-92 T 28-03-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS22170 bb411f7110f0b79e578f44ee1821bd64 312 Gene3D G3DSA:3.40.50.720 2 252 5.8E-21 T 28-03-2018 CNX65_RS22170 bb411f7110f0b79e578f44ee1821bd64 312 SUPERFAMILY SSF51735 5 277 1.16E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22170 bb411f7110f0b79e578f44ee1821bd64 312 Pfam PF05368 NmrA-like family 5 250 2.6E-34 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CNX65_RS02385 b03d2bc50f49a6dd4b6c2b817378a43d 87 Gene3D G3DSA:3.10.20.30 4 87 9.6E-19 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS02385 b03d2bc50f49a6dd4b6c2b817378a43d 87 SUPERFAMILY SSF54285 3 85 1.91E-10 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CNX65_RS02385 b03d2bc50f49a6dd4b6c2b817378a43d 87 Pfam PF02597 ThiS family 6 87 3.9E-8 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 8.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 8.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 8.5E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 Gene3D G3DSA:3.40.50.720 6 49 6.5E-9 T 28-03-2018 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 Gene3D G3DSA:3.40.50.720 50 256 2.6E-55 T 28-03-2018 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 253 2.4E-50 T 28-03-2018 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 16 254 1.9E-98 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 SUPERFAMILY SSF51735 13 254 8.11E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 102 122 4.8E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 232 251 4.8E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 82 99 4.8E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 20 37 4.8E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 206 225 4.8E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS13835 12dbaac6622feaf4c66a6ff4f869e5b9 256 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 167 190 4.8E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 1012 1173 2.1E-13 T 28-03-2018 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 SUPERFAMILY SSF51294 2961 3101 6.28E-18 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Gene3D G3DSA:3.90.210.10 3109 3227 5.1E-23 T 28-03-2018 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2296 2333 3.5E-7 T 28-03-2018 IPR006530 YD repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1730 1760 6.2E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2134 2164 2.0E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 2045 2085 2.4E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1948 1982 9.0E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1595 1631 5.1E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 SMART SM00282 1028 1169 6.4E-4 T 28-03-2018 IPR001791 Laminin G domain CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF07591 Pretoxin HINT domain 2969 3103 2.9E-17 T 28-03-2018 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Gene3D G3DSA:2.170.16.10 2946 3102 1.0E-34 T 28-03-2018 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF01375 Heat-labile enterotoxin alpha chain 3109 3202 3.0E-5 T 28-03-2018 IPR001144 Heat-labile enterotoxin, A chain GO:0005615|GO:0009405|GO:0090729 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF05593 RHS Repeat 2276 2310 2.8E-6 T 28-03-2018 IPR031325 RHS repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF05593 RHS Repeat 2046 2082 3.2E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF05593 RHS Repeat 1595 1631 8.3E-8 T 28-03-2018 IPR031325 RHS repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF05593 RHS Repeat 1948 1982 1.7E-6 T 28-03-2018 IPR031325 RHS repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF05593 RHS Repeat 1752 1788 6.3E-5 T 28-03-2018 IPR031325 RHS repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF05593 RHS Repeat 2296 2332 2.0E-6 T 28-03-2018 IPR031325 RHS repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Pfam PF05593 RHS Repeat 2134 2167 1.8E-6 T 28-03-2018 IPR031325 RHS repeat CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 SUPERFAMILY SSF49899 1005 1180 1.12E-18 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 SMART SM00306 2958 3060 1.0E-9 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2592 2671 4.5E-17 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 Gene3D G3DSA:2.60.120.200 1006 1826 2.5E-26 T 28-03-2018 CNX65_RS19615 fcc9cd489b872c814a359766f3cb958e 3230 SUPERFAMILY SSF56399 3113 3214 1.08E-19 T 28-03-2018 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 SUPERFAMILY SSF47203 244 386 2.58E-20 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 Gene3D G3DSA:2.40.110.10 134 217 8.3E-18 T 28-03-2018 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 Gene3D G3DSA:1.20.140.10 218 390 2.8E-21 T 28-03-2018 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 138 218 1.2E-8 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 250 369 2.0E-15 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 104 2.7E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 Gene3D G3DSA:1.10.540.10 8 109 2.5E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 PIRSF PIRSF016578 6 390 4.9E-30 T 28-03-2018 CNX65_RS21595 6f6a79759d4e5a6522c32e427228f233 391 SUPERFAMILY SSF56645 15 226 1.31E-33 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 SMART SM00928 328 373 5.0E-23 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 SUPERFAMILY SSF142984 241 323 5.62E-23 T 28-03-2018 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 SUPERFAMILY SSF140490 326 417 6.54E-34 T 28-03-2018 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 ProSitePatterns PS00645 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. 341 352 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 SUPERFAMILY SSF142019 7 239 4.58E-86 T 28-03-2018 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 Pfam PF01512 Respiratory-chain NADH dehydrogenase 51 Kd subunit 49 219 1.0E-46 T 28-03-2018 IPR011538 NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 Pfam PF10589 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region 332 412 9.0E-31 T 28-03-2018 IPR019575 NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain GO:0051539 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 ProSitePatterns PS00644 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. 167 182 - T 28-03-2018 IPR001949 NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site GO:0008137|GO:0010181|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 Gene3D G3DSA:3.10.560.10 234 326 4.9E-6 T 28-03-2018 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 Pfam PF10531 SLBB domain 244 289 2.4E-10 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32905 1667b13f5534fcac92f46845663c2cec 431 TIGRFAM TIGR01959 nuoF_fam: NADH oxidoreductase (quinone), F subunit 9 412 1.1E-187 T 28-03-2018 IPR011537 NADH ubiquinone oxidoreductase, F subunit GO:0010181|GO:0016651|GO:0051287|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS13420 d8a65ba4479c51784dcad765a004e202 458 Gene3D G3DSA:1.20.1250.20 20 231 1.8E-37 T 28-03-2018 CNX65_RS13420 d8a65ba4479c51784dcad765a004e202 458 SUPERFAMILY SSF103473 20 445 4.05E-77 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13420 d8a65ba4479c51784dcad765a004e202 458 Pfam PF07690 Major Facilitator Superfamily 36 406 2.7E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS13420 d8a65ba4479c51784dcad765a004e202 458 Gene3D G3DSA:1.20.1250.20 246 446 1.0E-16 T 28-03-2018 CNX65_RS17290 dc8ce17a4bf6eb8de1d2158413c8788f 469 SUPERFAMILY SSF103473 18 46 1.96E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS17290 dc8ce17a4bf6eb8de1d2158413c8788f 469 SUPERFAMILY SSF103473 80 456 1.96E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS17290 dc8ce17a4bf6eb8de1d2158413c8788f 469 Gene3D G3DSA:1.20.1250.20 260 458 6.2E-18 T 28-03-2018 CNX65_RS17290 dc8ce17a4bf6eb8de1d2158413c8788f 469 Gene3D G3DSA:1.20.1250.20 19 250 4.2E-16 T 28-03-2018 CNX65_RS17290 dc8ce17a4bf6eb8de1d2158413c8788f 469 Pfam PF11700 Vacuole effluxer Atg22 like 13 174 3.5E-36 T 28-03-2018 IPR024671 Autophagy-related protein 22-like CNX65_RS17290 dc8ce17a4bf6eb8de1d2158413c8788f 469 Pfam PF11700 Vacuole effluxer Atg22 like 177 461 7.6E-62 T 28-03-2018 IPR024671 Autophagy-related protein 22-like CNX65_RS07095 a5d5e0b9188a822d6cb587275563a55f 151 Pfam PF03477 ATP cone domain 47 132 9.1E-15 T 28-03-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 CNX65_RS07095 a5d5e0b9188a822d6cb587275563a55f 151 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 150 75.807 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CNX65_RS07095 a5d5e0b9188a822d6cb587275563a55f 151 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 2 144 1.3E-47 T 28-03-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 CNX65_RS28085 5305813c88e5e259a8fb6ff714dcec01 339 Pfam PF02445 Quinolinate synthetase A protein 27 331 9.6E-110 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CNX65_RS28085 5305813c88e5e259a8fb6ff714dcec01 339 SUPERFAMILY SSF142754 23 332 7.59E-101 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CNX65_RS28085 5305813c88e5e259a8fb6ff714dcec01 339 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 23 332 8.2E-91 T 28-03-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 CNX65_RS28085 5305813c88e5e259a8fb6ff714dcec01 339 Gene3D G3DSA:3.40.50.10800 192 314 1.9E-25 T 28-03-2018 CNX65_RS28085 5305813c88e5e259a8fb6ff714dcec01 339 Gene3D G3DSA:3.40.50.10800 23 110 4.8E-20 T 28-03-2018 CNX65_RS28085 5305813c88e5e259a8fb6ff714dcec01 339 Gene3D G3DSA:3.40.50.10800 111 191 1.5E-23 T 28-03-2018 CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 Gene3D G3DSA:3.40.50.720 3 188 2.9E-54 T 28-03-2018 CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 7.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 7.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 7.7E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 11 193 0.0024 T 28-03-2018 CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 Gene3D G3DSA:3.40.50.720 189 247 0.016 T 28-03-2018 CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 Pfam PF00106 short chain dehydrogenase 11 200 1.2E-51 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 SUPERFAMILY SSF51735 7 243 1.2E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 3.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 3.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 3.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 3.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11410 98057e58f207793dc9866de61f6a8a6a 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.3E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 Gene3D G3DSA:1.10.1660.10 1 57 6.8E-20 T 28-03-2018 CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 SMART SM00871 119 278 1.6E-14 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 SMART SM00422 2 72 2.1E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 SUPERFAMILY SSF55136 120 277 4.88E-16 T 28-03-2018 CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 Pfam PF06445 GyrI-like small molecule binding domain 120 277 8.7E-11 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 Pfam PF13411 MerR HTH family regulatory protein 3 70 1.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 SUPERFAMILY SSF46955 2 102 1.39E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 Gene3D G3DSA:1.10.1660.10 58 125 2.7E-11 T 28-03-2018 CNX65_RS12800 fc2a92125a6799e3c874269f4013ed51 287 Gene3D G3DSA:3.20.80.10 126 280 1.8E-23 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CNX65_RS31010 0b3014c348c012ae25ab6c8ff9d7dc52 253 Gene3D G3DSA:3.90.1680.10 1 245 9.1E-77 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CNX65_RS31010 0b3014c348c012ae25ab6c8ff9d7dc52 253 SUPERFAMILY SSF143081 2 237 6.15E-67 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CNX65_RS31010 0b3014c348c012ae25ab6c8ff9d7dc52 253 Pfam PF02586 SOS response associated peptidase (SRAP) 2 225 6.8E-69 T 28-03-2018 IPR003738 SOS response associated peptidase (SRAP) CNX65_RS21475 8251217163dd8344cc890687f7d251d0 427 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 66 416 2.1E-92 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CNX65_RS21475 8251217163dd8344cc890687f7d251d0 427 TIGRFAM TIGR01412 tat_substr_1: Tat-translocated enzyme 8 427 4.2E-156 T 28-03-2018 IPR006313 Deferrochelatase/peroxidase EfeB GO:0004601|GO:0015684|GO:0020037|GO:0033212 CNX65_RS21475 8251217163dd8344cc890687f7d251d0 427 SUPERFAMILY SSF54909 61 421 5.9E-90 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS21475 8251217163dd8344cc890687f7d251d0 427 Pfam PF04261 Dyp-type peroxidase family 66 416 4.2E-104 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CNX65_RS30515 2ad70d50c9451a95f56b0246ce3950c2 425 SUPERFAMILY SSF51621 178 409 5.76E-49 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS30515 2ad70d50c9451a95f56b0246ce3950c2 425 Gene3D G3DSA:3.20.20.60 173 422 3.6E-46 T 28-03-2018 CNX65_RS30515 2ad70d50c9451a95f56b0246ce3950c2 425 Pfam PF13714 Phosphoenolpyruvate phosphomutase 181 403 9.0E-62 T 28-03-2018 CNX65_RS30515 2ad70d50c9451a95f56b0246ce3950c2 425 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 158 167 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS17430 50b12fb3412f3d3eb381f7b6f953090a 225 SUPERFAMILY SSF53474 14 210 3.38E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17430 50b12fb3412f3d3eb381f7b6f953090a 225 Gene3D G3DSA:3.40.50.1820 6 225 1.5E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09460 e569fce67d3a39cd39ed18149ac208df 413 SUPERFAMILY SSF52266 362 392 2.5E-19 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS09460 e569fce67d3a39cd39ed18149ac208df 413 SUPERFAMILY SSF52266 35 324 2.5E-19 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS09460 e569fce67d3a39cd39ed18149ac208df 413 Gene3D G3DSA:3.40.50.1110 29 399 1.7E-20 T 28-03-2018 CNX65_RS09200 b2da0cb0153add51be70322184580c3b 319 SUPERFAMILY SSF51126 7 318 6.6E-59 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS09200 b2da0cb0153add51be70322184580c3b 319 Pfam PF01095 Pectinesterase 12 313 2.4E-43 T 28-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CNX65_RS09200 b2da0cb0153add51be70322184580c3b 319 Gene3D G3DSA:2.160.20.10 3 319 5.9E-74 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS18965 a093cfa5e558c66a74a36cce766fa971 453 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 453 53.562 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS18965 a093cfa5e558c66a74a36cce766fa971 453 Pfam PF00709 Adenylosuccinate synthetase 23 444 4.9E-82 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS18965 a093cfa5e558c66a74a36cce766fa971 453 SMART SM00788 22 447 2.4E-20 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS18965 a093cfa5e558c66a74a36cce766fa971 453 Gene3D G3DSA:3.90.170.10 296 451 1.7E-23 T 28-03-2018 CNX65_RS18965 a093cfa5e558c66a74a36cce766fa971 453 SUPERFAMILY SSF52540 21 448 1.38E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18965 a093cfa5e558c66a74a36cce766fa971 453 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 29 36 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS18965 a093cfa5e558c66a74a36cce766fa971 453 Gene3D G3DSA:3.40.440.10 19 295 8.5E-42 T 28-03-2018 CNX65_RS06690 957ffc610e7fd2dde48ed3d40b5ba64b 202 Gene3D G3DSA:3.40.50.720 2 201 4.5E-17 T 28-03-2018 CNX65_RS06690 957ffc610e7fd2dde48ed3d40b5ba64b 202 SUPERFAMILY SSF51735 2 200 2.0E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06690 957ffc610e7fd2dde48ed3d40b5ba64b 202 Pfam PF13460 NAD(P)H-binding 7 191 3.4E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25385 4ed186631380c9354b011c39dfa71939 171 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 168 1.4E-17 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CNX65_RS25385 4ed186631380c9354b011c39dfa71939 171 SUPERFAMILY SSF81296 32 169 4.9E-33 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS25385 4ed186631380c9354b011c39dfa71939 171 Gene3D G3DSA:2.70.50.50 32 170 3.2E-29 T 28-03-2018 CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 PIRSF PIRSF000089 1 319 5.1E-101 T 28-03-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 Pfam PF01012 Electron transfer flavoprotein domain 4 172 1.1E-29 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 SUPERFAMILY SSF52402 4 181 1.47E-38 T 28-03-2018 CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 195 277 2.8E-36 T 28-03-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 Gene3D G3DSA:3.40.50.620 1 186 1.5E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 SUPERFAMILY SSF52467 192 313 1.85E-48 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 Gene3D G3DSA:3.40.50.1220 191 319 6.2E-60 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 SMART SM00893 4 182 1.4E-23 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CNX65_RS29775 72e66d48dfe6646a0bd295ebaf8080cc 319 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 258 284 - T 28-03-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 CNX65_RS09425 7aa68ecf6bc081bdeaeb62f4e652ac1a 354 SUPERFAMILY SSF52540 52 287 3.19E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09425 7aa68ecf6bc081bdeaeb62f4e652ac1a 354 Gene3D G3DSA:3.40.50.300 48 244 5.9E-18 T 28-03-2018 CNX65_RS09425 7aa68ecf6bc081bdeaeb62f4e652ac1a 354 Pfam PF07728 AAA domain (dynein-related subfamily) 72 213 3.4E-32 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CNX65_RS09425 7aa68ecf6bc081bdeaeb62f4e652ac1a 354 SMART SM00382 68 223 0.0024 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01045 8df3225e58ca5510dc4425bbca675f34 140 SUPERFAMILY SSF82784 1 138 1.83E-43 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS01045 8df3225e58ca5510dc4425bbca675f34 140 Gene3D G3DSA:2.20.25.10 1 28 2.6E-14 T 28-03-2018 CNX65_RS01045 8df3225e58ca5510dc4425bbca675f34 140 Gene3D G3DSA:3.30.300.20 29 140 5.1E-33 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS01045 8df3225e58ca5510dc4425bbca675f34 140 Pfam PF02566 OsmC-like protein 41 136 2.1E-20 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS01045 8df3225e58ca5510dc4425bbca675f34 140 TIGRFAM TIGR03561 organ_hyd_perox: peroxiredoxin, Ohr subfamily 4 137 1.5E-54 T 28-03-2018 IPR019953 Organic hydroperoxide resistance protein famiy GO:0006979 CNX65_RS00345 2caafedeea7eaa02caeb333bcbd0d4a6 290 Gene3D G3DSA:3.90.226.10 16 283 2.0E-35 T 28-03-2018 CNX65_RS00345 2caafedeea7eaa02caeb333bcbd0d4a6 290 Pfam PF01343 Peptidase family S49 95 236 2.0E-29 T 28-03-2018 IPR002142 Peptidase S49 GO:0006508|GO:0008233 CNX65_RS00345 2caafedeea7eaa02caeb333bcbd0d4a6 290 SUPERFAMILY SSF52096 16 141 3.2E-37 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS00345 2caafedeea7eaa02caeb333bcbd0d4a6 290 SUPERFAMILY SSF52096 170 232 3.2E-37 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS24665 7240e3719ca042a61c58fdda89c61932 200 Gene3D G3DSA:3.10.490.10 3 196 2.2E-22 T 28-03-2018 CNX65_RS15270 56f45c0394878554f430368fd06503ba 607 Gene3D G3DSA:1.20.1560.10 30 352 1.4E-55 T 28-03-2018 CNX65_RS15270 56f45c0394878554f430368fd06503ba 607 SUPERFAMILY SSF90123 41 356 3.53E-57 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS15270 56f45c0394878554f430368fd06503ba 607 SUPERFAMILY SSF52540 360 603 1.59E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15270 56f45c0394878554f430368fd06503ba 607 Gene3D G3DSA:3.40.50.300 353 607 3.5E-48 T 28-03-2018 CNX65_RS15270 56f45c0394878554f430368fd06503ba 607 Pfam PF00664 ABC transporter transmembrane region 54 322 3.3E-31 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS15270 56f45c0394878554f430368fd06503ba 607 SMART SM00382 390 579 2.1E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15270 56f45c0394878554f430368fd06503ba 607 Pfam PF00005 ABC transporter 381 534 2.6E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 4 312 27.609 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 SUPERFAMILY SSF52440 6 97 3.93E-21 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 Gene3D G3DSA:3.40.50.20 2 78 1.4E-20 T 28-03-2018 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 SUPERFAMILY SSF56059 97 308 3.71E-44 T 28-03-2018 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 Pfam PF01820 D-ala D-ala ligase N-terminus 6 86 3.5E-13 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 Gene3D G3DSA:3.30.470.20 174 314 1.6E-34 T 28-03-2018 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 Pfam PF07478 D-ala D-ala ligase C-terminus 106 309 1.1E-40 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 PIRSF PIRSF039102 2 52 1.9E-6 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 PIRSF PIRSF039102 36 314 1.0E-61 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS35035 c49126e01ed2c6feab66f5a329952817 314 Gene3D G3DSA:3.30.1490.20 79 173 8.7E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 146 208 7.2E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 129 8.4E-27 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 PIRSF PIRSF000709 3 112 5.6E-4 T 28-03-2018 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 PIRSF PIRSF000709 135 214 0.068 T 28-03-2018 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 SMART SM00855 5 190 3.4E-24 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 TIGRFAM TIGR01258 pgm_1: phosphoglycerate mutase 1 family 5 248 5.1E-109 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 SUPERFAMILY SSF53254 5 222 1.07E-70 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 Hamap MF_01039 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase [gpmA]. 3 231 42.332 T 28-03-2018 IPR005952 Phosphoglycerate mutase 1 GO:0004619|GO:0006096|GO:0016868 KEGG: 00010+5.4.2.11|KEGG: 00260+5.4.2.11|KEGG: 00680+5.4.2.11|MetaCyc: PWY-1622|MetaCyc: PWY-5484 CNX65_RS33285 962edc7b892e4abd1ef3860099eea1df 248 Gene3D G3DSA:3.40.50.1240 2 248 2.0E-60 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 SUPERFAMILY SSF54534 86 158 8.11E-11 T 28-03-2018 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 Pfam PF03449 Transcription elongation factor, N-terminal 10 78 3.0E-23 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 Gene3D G3DSA:1.10.287.180 8 80 9.8E-24 T 28-03-2018 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 Hamap MF_00105 Transcription elongation factor GreA [greA]. 7 160 27.326 T 28-03-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 SUPERFAMILY SSF46557 9 80 1.7E-21 T 28-03-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 22 52 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 PIRSF PIRSF006092 3 162 9.2E-31 T 28-03-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 88 158 8.8E-13 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 124 140 - T 28-03-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 CNX65_RS03520 3b78eba30f519324668522b146b3c034 164 Gene3D G3DSA:3.10.50.30 81 164 2.9E-15 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CNX65_RS30180 48bab1fc9417115a87ec9746d4c46159 190 Gene3D G3DSA:1.20.1200.10 17 190 1.5E-53 T 28-03-2018 CNX65_RS30180 48bab1fc9417115a87ec9746d4c46159 190 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 9 179 9.1E-48 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CNX65_RS30180 48bab1fc9417115a87ec9746d4c46159 190 Pfam PF01923 Cobalamin adenosyltransferase 8 175 4.2E-54 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CNX65_RS30180 48bab1fc9417115a87ec9746d4c46159 190 SUPERFAMILY SSF89028 6 184 2.35E-54 T 28-03-2018 IPR016030 Adenosylcobalamin biosynthesis, ATP:cob(I)alamin adenosyltransferase-like KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CNX65_RS30180 48bab1fc9417115a87ec9746d4c46159 190 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 184 2.0E-55 T 28-03-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269|Reactome: R-HSA-196741 CNX65_RS21530 505403b866df25008385d54d92fd952c 250 Gene3D G3DSA:3.30.450.40 14 197 5.6E-22 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS21530 505403b866df25008385d54d92fd952c 250 Pfam PF13185 GAF domain 32 174 8.9E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS21530 505403b866df25008385d54d92fd952c 250 Gene3D G3DSA:1.10.10.10 198 243 9.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21530 505403b866df25008385d54d92fd952c 250 SMART SM01012 186 241 3.6E-23 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS21530 505403b866df25008385d54d92fd952c 250 SUPERFAMILY SSF55781 36 183 1.0E-17 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS21530 505403b866df25008385d54d92fd952c 250 SUPERFAMILY SSF52172 166 240 3.73E-11 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS21530 505403b866df25008385d54d92fd952c 250 Pfam PF03861 ANTAR domain 188 239 7.7E-22 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS21530 505403b866df25008385d54d92fd952c 250 PIRSF PIRSF036625 12 249 9.9E-57 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CNX65_RS25780 aa95ab4fd5ab50b721b03e93a2055ea0 184 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 175 4.1E-23 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25780 aa95ab4fd5ab50b721b03e93a2055ea0 184 Pfam PF04542 Sigma-70 region 2 24 86 1.1E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25780 aa95ab4fd5ab50b721b03e93a2055ea0 184 Pfam PF08281 Sigma-70, region 4 119 171 3.0E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25780 aa95ab4fd5ab50b721b03e93a2055ea0 184 Gene3D G3DSA:1.10.1740.10 4 92 1.2E-18 T 28-03-2018 CNX65_RS25780 aa95ab4fd5ab50b721b03e93a2055ea0 184 SUPERFAMILY SSF88659 102 177 6.35E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25780 aa95ab4fd5ab50b721b03e93a2055ea0 184 SUPERFAMILY SSF88946 6 106 1.96E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25780 aa95ab4fd5ab50b721b03e93a2055ea0 184 Gene3D G3DSA:1.10.10.10 98 180 4.6E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 Gene3D G3DSA:3.40.50.2300 57 178 8.4E-30 T 28-03-2018 CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 5.4E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 SMART SM00354 3 73 1.6E-24 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 Gene3D G3DSA:1.10.260.40 18 56 4.8E-24 T 28-03-2018 CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 SUPERFAMILY SSF53822 63 328 6.48E-72 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 Gene3D G3DSA:1.10.10.60 1 17 0.086 T 28-03-2018 CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 Gene3D G3DSA:3.40.50.2300 179 308 9.4E-46 T 28-03-2018 CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 SUPERFAMILY SSF47413 3 61 9.14E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS17625 cc0e0b3ca0a3828eeb3bc943e5ec29f1 331 Pfam PF13377 Periplasmic binding protein-like domain 172 327 7.6E-39 T 28-03-2018 CNX65_RS01515 863baad8aed9abafad859ebe2deb86e9 399 Pfam PF13177 DNA polymerase III, delta subunit 38 181 3.4E-35 T 28-03-2018 CNX65_RS01515 863baad8aed9abafad859ebe2deb86e9 399 Gene3D G3DSA:1.20.272.10 296 399 6.2E-27 T 28-03-2018 CNX65_RS01515 863baad8aed9abafad859ebe2deb86e9 399 SUPERFAMILY SSF52540 6 221 8.64E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01515 863baad8aed9abafad859ebe2deb86e9 399 Gene3D G3DSA:3.40.50.300 6 184 7.0E-26 T 28-03-2018 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 Pfam PF02897 Prolyl oligopeptidase, N-terminal beta-propeller domain 17 430 1.6E-75 T 28-03-2018 IPR023302 Peptidase S9A, N-terminal domain GO:0004252|GO:0070008 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 Pfam PF00326 Prolyl oligopeptidase family 497 706 1.5E-50 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 ProSitePatterns PS00708 Prolyl endopeptidase family serine active site. 537 567 - T 28-03-2018 IPR002471 Peptidase S9, serine active site GO:0004252|GO:0006508 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 502 526 4.5E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 560 580 4.5E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 530 549 4.5E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 615 630 4.5E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 634 656 4.5E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 PRINTS PR00862 Prolyl oligopeptidase serine protease (S9A) signature 476 494 4.5E-42 T 28-03-2018 IPR002470 Peptidase S9A, prolyl oligopeptidase GO:0004252|GO:0006508 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 SUPERFAMILY SSF50993 12 432 7.59E-74 T 28-03-2018 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 SUPERFAMILY SSF53474 446 702 1.77E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 Gene3D G3DSA:2.130.10.120 83 430 1.8E-43 T 28-03-2018 CNX65_RS05660 dffb32fd2d48c769d0aa5b426b6d90b4 710 Gene3D G3DSA:3.40.50.1820 431 709 1.1E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 SUPERFAMILY SSF55781 47 186 1.26E-16 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 SMART SM00065 42 193 2.6E-4 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 SMART SM00065 214 365 2.2E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 Gene3D G3DSA:1.10.287.950 357 521 9.7E-39 T 28-03-2018 CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 383 504 6.9E-33 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 Gene3D G3DSA:3.30.450.40 21 192 1.8E-21 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 Gene3D G3DSA:3.30.450.40 193 356 2.2E-21 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 SMART SM00283 318 518 5.3E-12 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 SUPERFAMILY SSF58104 350 519 8.37E-44 T 28-03-2018 CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 SUPERFAMILY SSF55781 198 359 4.36E-17 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 Pfam PF13185 GAF domain 212 355 4.0E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS13930 65782e63940c6f9bc367ec05300a823a 522 Pfam PF13185 GAF domain 44 184 3.2E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 TIGRFAM TIGR02412 pepN_strep_liv: aminopeptidase N 5 848 0.0 T 28-03-2018 IPR012778 Peptidase M1, aminopeptidase GO:0004177|GO:0006508 KEGG: 00480+3.4.11.2|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 SUPERFAMILY SSF55486 216 460 8.06E-76 T 28-03-2018 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 185 200 4.2E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 268 278 4.2E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 321 333 4.2E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 302 317 4.2E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 137 152 4.2E-23 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 SUPERFAMILY SSF63737 6 202 2.88E-40 T 28-03-2018 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 Pfam PF01433 Peptidase family M1 domain 217 450 4.3E-57 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 Gene3D G3DSA:2.60.40.1730 17 203 3.9E-36 T 28-03-2018 CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 Pfam PF11838 ERAP1-like C-terminal domain 533 840 4.7E-63 T 28-03-2018 IPR024571 ERAP1-like C-terminal domain CNX65_RS05685 f003884888d8db3ebcd84a34189bfe95 852 Gene3D G3DSA:1.10.390.10 288 454 2.8E-45 T 28-03-2018 CNX65_RS30215 cc08b1e985dfc98bdf13f4aa60b2ed17 182 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 29 173 1.0E-25 T 28-03-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 CNX65_RS30215 cc08b1e985dfc98bdf13f4aa60b2ed17 182 Hamap MF_01398 ATP synthase subunit b [atpF]. 16 154 12.038 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CNX65_RS30215 cc08b1e985dfc98bdf13f4aa60b2ed17 182 Pfam PF00430 ATP synthase B/B' CF(0) 23 152 4.4E-28 T 28-03-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 CNX65_RS30215 cc08b1e985dfc98bdf13f4aa60b2ed17 182 SUPERFAMILY SSF81573 78 137 1.31E-13 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS30215 cc08b1e985dfc98bdf13f4aa60b2ed17 182 Gene3D G3DSA:1.20.5.620 78 138 5.9E-16 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS07545 1e536c7ce713de2d3d7dbe603f6d98d7 411 Gene3D G3DSA:3.40.50.150 79 408 1.1E-41 T 28-03-2018 CNX65_RS07545 1e536c7ce713de2d3d7dbe603f6d98d7 411 Gene3D G3DSA:2.40.50.140 4 78 5.1E-23 T 28-03-2018 CNX65_RS07545 1e536c7ce713de2d3d7dbe603f6d98d7 411 Pfam PF01938 TRAM domain 9 55 2.1E-9 T 28-03-2018 IPR002792 TRAM domain CNX65_RS07545 1e536c7ce713de2d3d7dbe603f6d98d7 411 SUPERFAMILY SSF50249 10 69 1.03E-11 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS07545 1e536c7ce713de2d3d7dbe603f6d98d7 411 SUPERFAMILY SSF53335 70 409 5.08E-52 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS07545 1e536c7ce713de2d3d7dbe603f6d98d7 411 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 392 402 - T 28-03-2018 IPR030391 RNA methyltransferase TrmA, conserved site CNX65_RS07545 1e536c7ce713de2d3d7dbe603f6d98d7 411 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 334 408 4.8E-10 T 28-03-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 CNX65_RS20500 2a9e3d868478f0a4d7d6eb78a4120463 378 Gene3D G3DSA:3.40.50.720 1 153 1.5E-38 T 28-03-2018 CNX65_RS20500 2a9e3d868478f0a4d7d6eb78a4120463 378 SUPERFAMILY SSF55347 141 302 2.13E-34 T 28-03-2018 CNX65_RS20500 2a9e3d868478f0a4d7d6eb78a4120463 378 SUPERFAMILY SSF51735 5 167 3.16E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20500 2a9e3d868478f0a4d7d6eb78a4120463 378 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 147 233 5.5E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS20500 2a9e3d868478f0a4d7d6eb78a4120463 378 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 126 3.4E-24 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS20500 2a9e3d868478f0a4d7d6eb78a4120463 378 Gene3D G3DSA:3.30.360.10 154 378 2.7E-51 T 28-03-2018 CNX65_RS10785 136fc72c6de674c24ce5b8f6641985a3 391 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 63 3.3E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10785 136fc72c6de674c24ce5b8f6641985a3 391 Gene3D G3DSA:1.10.10.60 5 50 5.3E-17 T 28-03-2018 CNX65_RS10785 136fc72c6de674c24ce5b8f6641985a3 391 SUPERFAMILY SSF46689 4 70 2.41E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS10785 136fc72c6de674c24ce5b8f6641985a3 391 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10785 136fc72c6de674c24ce5b8f6641985a3 391 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10785 136fc72c6de674c24ce5b8f6641985a3 391 Gene3D G3DSA:1.10.10.60 51 214 1.6E-8 T 28-03-2018 CNX65_RS24880 d0255dfbaee85b2b8103a5eb12dd323b 193 Gene3D G3DSA:1.10.357.10 8 193 1.4E-28 T 28-03-2018 CNX65_RS24880 d0255dfbaee85b2b8103a5eb12dd323b 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 1.7E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24880 d0255dfbaee85b2b8103a5eb12dd323b 193 SUPERFAMILY SSF48498 81 191 2.16E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS24880 d0255dfbaee85b2b8103a5eb12dd323b 193 SUPERFAMILY SSF46689 2 81 2.29E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS24880 d0255dfbaee85b2b8103a5eb12dd323b 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24880 d0255dfbaee85b2b8103a5eb12dd323b 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11940 69273d2cbe73ceb81eda83f7000923d1 215 Pfam PF02108 Flagellar assembly protein FliH 84 208 6.7E-12 T 28-03-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE CNX65_RS19505 4709800c41aefd83b06776da6b9cc302 265 Pfam PF00486 Transcriptional regulatory protein, C terminal 26 95 8.5E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS19505 4709800c41aefd83b06776da6b9cc302 265 SUPERFAMILY SSF46894 5 95 2.24E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS19505 4709800c41aefd83b06776da6b9cc302 265 Gene3D G3DSA:1.10.10.10 12 108 1.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19505 4709800c41aefd83b06776da6b9cc302 265 SUPERFAMILY SSF48452 101 258 1.67E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS19505 4709800c41aefd83b06776da6b9cc302 265 SMART SM01043 102 246 8.5E-32 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS19505 4709800c41aefd83b06776da6b9cc302 265 SMART SM00862 18 95 3.8E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS19505 4709800c41aefd83b06776da6b9cc302 265 Pfam PF03704 Bacterial transcriptional activator domain 102 243 1.3E-28 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS30525 e33e469987a227bec10c0a059b3900fa 181 SUPERFAMILY SSF48498 78 180 4.45E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS30525 e33e469987a227bec10c0a059b3900fa 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 4.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS30525 e33e469987a227bec10c0a059b3900fa 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 6.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS30525 e33e469987a227bec10c0a059b3900fa 181 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.4E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS30525 e33e469987a227bec10c0a059b3900fa 181 Gene3D G3DSA:1.10.357.10 1 181 1.1E-33 T 28-03-2018 CNX65_RS30525 e33e469987a227bec10c0a059b3900fa 181 SUPERFAMILY SSF46689 3 78 1.5E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS19765 a0325cf9a3067292905b49a67db9461a 336 Pfam PF14011 EspG family 109 331 3.7E-29 T 28-03-2018 IPR025734 EspG family CNX65_RS33240 f33d1a0081ed100debf759d9c4944996 266 Gene3D G3DSA:3.10.129.10 145 266 0.0059 T 28-03-2018 CNX65_RS33240 f33d1a0081ed100debf759d9c4944996 266 SUPERFAMILY SSF54637 3 110 4.98E-13 T 28-03-2018 IPR029069 HotDog domain CNX65_RS33240 f33d1a0081ed100debf759d9c4944996 266 Pfam PF13622 Thioesterase-like superfamily 22 261 1.6E-37 T 28-03-2018 CNX65_RS33240 f33d1a0081ed100debf759d9c4944996 266 Gene3D G3DSA:3.10.129.10 1 110 8.8E-20 T 28-03-2018 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 ProSitePatterns PS00211 ABC transporters family signature. 513 527 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Gene3D G3DSA:1.20.1560.10 856 1179 9.2E-63 T 28-03-2018 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Gene3D G3DSA:3.40.50.300 366 614 5.8E-62 T 28-03-2018 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Gene3D G3DSA:3.40.50.300 1181 1434 3.6E-69 T 28-03-2018 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 SUPERFAMILY SSF52540 368 608 6.09E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Pfam PF00664 ABC transporter transmembrane region 64 329 3.5E-36 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Pfam PF00664 ABC transporter transmembrane region 879 1147 3.9E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 SUPERFAMILY SSF90123 48 364 3.27E-64 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Gene3D G3DSA:1.20.1560.10 45 365 1.4E-53 T 28-03-2018 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Pfam PF00005 ABC transporter 392 541 9.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 Pfam PF00005 ABC transporter 1210 1359 1.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 SUPERFAMILY SSF90123 861 1178 6.8E-76 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 SMART SM00382 401 587 3.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 SMART SM00382 1219 1405 1.2E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30780 95e5063ce00d479c38cdffa1e80da4f3 1494 SUPERFAMILY SSF52540 1184 1427 2.33E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 Gene3D G3DSA:3.30.300.20 17 106 1.6E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 Pfam PF07650 KH domain 37 109 5.6E-19 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 6.0E-93 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 202 1.5E-35 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 ProSitePatterns PS00548 Ribosomal protein S3 signature. 163 197 - T 28-03-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 SUPERFAMILY SSF54814 2 105 4.45E-37 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 SMART SM00322 59 124 2.0E-7 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 Gene3D G3DSA:3.30.1140.32 107 207 6.6E-35 T 28-03-2018 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 206 37.909 T 28-03-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 CNX65_RS32420 d2953c0b2744fdbb9dd53539abb96709 275 SUPERFAMILY SSF54821 106 206 5.62E-36 T 28-03-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 61 128 2.6E-26 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 SUPERFAMILY SSF54736 56 128 1.48E-20 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 63 104 1.0E-13 T 28-03-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 Gene3D G3DSA:1.20.5.710 4 56 4.5E-16 T 28-03-2018 CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 Gene3D G3DSA:3.30.1390.10 57 128 4.9E-27 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 6 51 4.9E-18 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 3 128 23.508 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 TIGRFAM TIGR00855 L12: ribosomal protein bL12 1 128 2.5E-46 T 28-03-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32560 8a35d17c6e7af8c2390ccf7defb0696e 128 SUPERFAMILY SSF48300 5 63 5.1E-14 T 28-03-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32310 e5f5939a6b8b4779501cb7c35024ad43 135 Pfam PF00411 Ribosomal protein S11 25 134 1.9E-48 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32310 e5f5939a6b8b4779501cb7c35024ad43 135 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 135 34.241 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32310 e5f5939a6b8b4779501cb7c35024ad43 135 Gene3D G3DSA:3.30.420.80 11 135 1.9E-45 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32310 e5f5939a6b8b4779501cb7c35024ad43 135 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 16 132 2.6E-59 T 28-03-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32310 e5f5939a6b8b4779501cb7c35024ad43 135 PIRSF PIRSF002131 4 135 1.5E-53 T 28-03-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32310 e5f5939a6b8b4779501cb7c35024ad43 135 SUPERFAMILY SSF53137 20 135 2.68E-49 T 28-03-2018 CNX65_RS32310 e5f5939a6b8b4779501cb7c35024ad43 135 ProSitePatterns PS00054 Ribosomal protein S11 signature. 103 125 - T 28-03-2018 IPR018102 Ribosomal S11, conserved site CNX65_RS24680 b31093db5cf33611ffea28b284e26c9e 325 Pfam PF02780 Transketolase, C-terminal domain 187 307 4.3E-40 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS24680 b31093db5cf33611ffea28b284e26c9e 325 Gene3D G3DSA:3.40.50.970 1 186 2.4E-60 T 28-03-2018 CNX65_RS24680 b31093db5cf33611ffea28b284e26c9e 325 SUPERFAMILY SSF52518 1 178 5.89E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS24680 b31093db5cf33611ffea28b284e26c9e 325 Pfam PF02779 Transketolase, pyrimidine binding domain 1 172 3.2E-44 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS24680 b31093db5cf33611ffea28b284e26c9e 325 SMART SM00861 1 174 2.1E-65 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS24680 b31093db5cf33611ffea28b284e26c9e 325 Gene3D G3DSA:3.40.50.920 187 315 1.8E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS24680 b31093db5cf33611ffea28b284e26c9e 325 SUPERFAMILY SSF52922 185 311 1.96E-39 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1 181 0.0069 T 28-03-2018 CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 7.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 207 227 7.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 7.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 7.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 7.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 37 54 7.3E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 79 90 2.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 3 243 2.1E-50 T 28-03-2018 CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 Gene3D G3DSA:3.40.50.720 32 245 8.5E-57 T 28-03-2018 CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 Gene3D G3DSA:3.40.50.720 1 31 5.3E-4 T 28-03-2018 CNX65_RS15865 e30368fd4b64df48ed955ada2cf1afe0 245 SUPERFAMILY SSF51735 1 243 4.72E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20570 a648c3f7234051033a214194cc133d4d 174 SMART SM00903 22 170 1.0E-63 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS20570 a648c3f7234051033a214194cc133d4d 174 SUPERFAMILY SSF50475 18 172 7.36E-51 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS20570 a648c3f7234051033a214194cc133d4d 174 Gene3D G3DSA:2.30.110.10 3 174 1.7E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS20570 a648c3f7234051033a214194cc133d4d 174 Pfam PF01613 Flavin reductase like domain 22 171 2.8E-41 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 PIRSF PIRSF000498 1 206 5.4E-71 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 Gene3D G3DSA:2.40.30.20 93 190 1.5E-37 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 SUPERFAMILY SSF63380 2 87 1.28E-23 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 Pfam PF00677 Lumazine binding domain 99 183 1.5E-26 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 Pfam PF00677 Lumazine binding domain 3 86 8.1E-22 T 28-03-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 Gene3D G3DSA:2.40.30.20 1 92 2.6E-26 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 SUPERFAMILY SSF63380 92 193 2.55E-33 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS25970 7ac9985b9e7ed183ab1141c144833b3b 209 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 2 192 3.8E-64 T 28-03-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 10 34 7.2E-7 T 28-03-2018 CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 7.2E-7 T 28-03-2018 CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 PRINTS PR01036 Tetracycline resistance protein TetB signature 393 412 7.2E-7 T 28-03-2018 CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 Gene3D G3DSA:1.20.1250.20 246 462 5.4E-9 T 28-03-2018 CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 Pfam PF07690 Major Facilitator Superfamily 13 414 1.7E-32 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 Gene3D G3DSA:1.20.1250.20 1 193 3.3E-28 T 28-03-2018 CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 SUPERFAMILY SSF103473 2 190 3.79E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS09755 6ba1fea6027bc52e2c6ada21083098ab 462 SUPERFAMILY SSF103473 242 458 3.79E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 Pfam PF07690 Major Facilitator Superfamily 15 414 9.5E-53 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 Gene3D G3DSA:1.20.1250.20 2 197 8.5E-34 T 28-03-2018 CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 12 426 2.9E-88 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 7.0E-9 T 28-03-2018 CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 7.0E-9 T 28-03-2018 CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 7.0E-9 T 28-03-2018 CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 SUPERFAMILY SSF103473 252 424 1.57E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 SUPERFAMILY SSF103473 4 194 1.57E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 SUPERFAMILY SSF103473 502 517 1.57E-70 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15365 0eb99f052a7a0cb84fdfab53725df81e 556 Gene3D G3DSA:1.20.1250.20 256 545 1.3E-30 T 28-03-2018 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 921 933 4.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 905 921 4.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 891 905 4.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Gene3D G3DSA:3.40.50.300 7 196 3.1E-13 T 28-03-2018 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Gene3D G3DSA:1.25.40.10 381 560 8.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 SMART SM00382 29 197 8.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Pfam PF00196 Bacterial regulatory proteins, luxR family 890 943 2.5E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 SUPERFAMILY SSF46894 880 945 6.46E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 SUPERFAMILY SSF52540 8 71 9.1E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 SUPERFAMILY SSF52540 103 257 9.1E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Gene3D G3DSA:1.25.40.10 608 785 5.3E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Gene3D G3DSA:1.25.40.10 786 900 5.9E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Pfam PF13191 AAA ATPase domain 8 167 1.2E-25 T 28-03-2018 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Gene3D G3DSA:1.10.10.10 901 949 3.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 SUPERFAMILY SSF48452 744 855 1.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 ProSitePatterns PS00622 LuxR-type HTH domain signature. 905 932 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 Gene3D G3DSA:1.25.40.10 561 607 0.059 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11420 25b2ad1825299694a78d0a81bad6f44f 949 SMART SM00421 888 945 4.0E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 Gene3D G3DSA:3.40.50.980 195 391 5.1E-42 T 28-03-2018 CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 Gene3D G3DSA:3.30.300.30 465 602 1.1E-14 T 28-03-2018 CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 Gene3D G3DSA:2.30.38.10 392 463 1.7E-20 T 28-03-2018 CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 ProSitePatterns PS00455 Putative AMP-binding domain signature. 189 200 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 Pfam PF00501 AMP-binding enzyme 23 470 1.8E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 SUPERFAMILY SSF56801 16 293 3.92E-119 T 28-03-2018 CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 SUPERFAMILY SSF56801 341 600 3.92E-119 T 28-03-2018 CNX65_RS06845 f1400abfba5f0476491af642ce1548fb 602 Gene3D G3DSA:3.40.50.980 14 194 8.3E-40 T 28-03-2018 CNX65_RS04875 633f1d036660578244d1139db426471d 428 Pfam PF01547 Bacterial extracellular solute-binding protein 48 334 2.3E-27 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS04875 633f1d036660578244d1139db426471d 428 SUPERFAMILY SSF53850 23 427 5.18E-55 T 28-03-2018 CNX65_RS04875 633f1d036660578244d1139db426471d 428 Gene3D G3DSA:3.40.190.10 266 372 1.3E-4 T 28-03-2018 CNX65_RS04875 633f1d036660578244d1139db426471d 428 Gene3D G3DSA:3.40.190.10 35 224 5.4E-36 T 28-03-2018 CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 Pfam PF00733 Asparagine synthase 252 621 1.7E-103 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 SUPERFAMILY SSF52402 479 617 1.63E-85 T 28-03-2018 CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 SUPERFAMILY SSF52402 245 392 1.63E-85 T 28-03-2018 CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 559 1.6E-141 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 SUPERFAMILY SSF56235 2 230 2.23E-55 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 Gene3D G3DSA:3.60.20.10 1 230 1.4E-46 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 PIRSF PIRSF001589 1 636 3.7E-174 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 Pfam PF13537 Glutamine amidotransferase domain 50 172 2.4E-38 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CNX65_RS06760 9c55036f89f854382b7c5a133d555a65 642 Gene3D G3DSA:3.40.50.620 231 624 5.4E-82 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 6.0E-9 T 28-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 Gene3D G3DSA:3.90.180.10 1 175 1.5E-49 T 28-03-2018 CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 SUPERFAMILY SSF51735 156 268 9.0E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 SUPERFAMILY SSF51735 299 363 9.0E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 143 9.8E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 SUPERFAMILY SSF50129 2 196 2.59E-57 T 28-03-2018 IPR011032 GroES-like CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 Gene3D G3DSA:3.40.50.720 176 357 1.5E-27 T 28-03-2018 CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 Pfam PF00107 Zinc-binding dehydrogenase 190 258 3.0E-12 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS17110 3be19c64b766c70cfe97b3e70fdfe9b1 403 SMART SM00829 8 323 5.6E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 Gene3D G3DSA:3.40.50.1110 21 232 9.2E-33 T 28-03-2018 CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 SUPERFAMILY SSF52266 18 226 5.5E-34 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 Pfam PF00652 Ricin-type beta-trefoil lectin domain 241 362 3.1E-30 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 Gene3D G3DSA:2.80.10.50 256 290 6.3E-15 T 28-03-2018 CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 Gene3D G3DSA:2.80.10.50 324 366 2.4E-13 T 28-03-2018 CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 39 215 4.9E-18 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 SMART SM00458 238 365 4.6E-32 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 SUPERFAMILY SSF50370 238 364 2.49E-41 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 Gene3D G3DSA:2.80.10.50 291 323 8.8E-14 T 28-03-2018 CNX65_RS15745 41ad3940b9ca84fd956efbcd9194e929 368 Gene3D G3DSA:2.80.10.50 234 255 0.3 T 28-03-2018 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 SUPERFAMILY SSF51989 31 314 3.4E-88 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 Pfam PF01341 Glycosyl hydrolases family 6 40 296 3.8E-67 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 99 115 - T 28-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 122 137 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 179 192 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 257 277 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 242 255 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 51 70 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 94 107 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 210 220 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PRINTS PR00733 Glycosyl hydrolase family 6 signature 281 295 1.3E-45 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 Gene3D G3DSA:3.20.20.40 29 315 2.8E-90 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PIRSF PIRSF001100 2 318 3.1E-84 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 PIRSF PIRSF001100 320 444 1.2 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 Gene3D G3DSA:2.60.40.290 334 443 2.1E-24 T 28-03-2018 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 SMART SM00637 345 443 1.2E-23 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 Pfam PF00553 Cellulose binding domain 345 443 1.1E-20 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS11055 f17b66a514109e26077f14e29eba006d 444 SUPERFAMILY SSF49384 339 443 5.16E-22 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS29765 006cfcb0265e0033ce543dd16ba9d8b2 330 Gene3D G3DSA:3.40.1130.10 55 268 1.3E-23 T 28-03-2018 CNX65_RS29765 006cfcb0265e0033ce543dd16ba9d8b2 330 SUPERFAMILY SSF69593 87 248 3.53E-21 T 28-03-2018 CNX65_RS29765 006cfcb0265e0033ce543dd16ba9d8b2 330 Pfam PF01553 Acyltransferase 89 201 1.3E-19 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS29765 006cfcb0265e0033ce543dd16ba9d8b2 330 SMART SM00563 92 204 5.5E-28 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 141 155 1.2E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 225 239 1.2E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 276 287 1.2E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 118 137 1.2E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 PRINTS PR00416 Eukaryotic DNA topoisomerase I signature 162 178 1.2E-7 T 28-03-2018 IPR001631 DNA topoisomerase I GO:0003677|GO:0003917|GO:0006265 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 Gene3D G3DSA:3.30.66.10 15 80 7.8E-32 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 Gene3D G3DSA:3.90.15.10 81 221 4.3E-30 T 28-03-2018 IPR014711 DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 SUPERFAMILY SSF56349 78 295 2.21E-52 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 Pfam PF01028 Eukaryotic DNA topoisomerase I, catalytic core 82 280 2.6E-22 T 28-03-2018 IPR013500 DNA topoisomerase I, catalytic core, eukaryotic-type GO:0003677|GO:0003917|GO:0006265 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 Gene3D G3DSA:1.20.120.380 227 310 1.1E-25 T 28-03-2018 IPR027362 DNA topoisomerase I catalytic fragment, domain 2 CNX65_RS23805 c572293e56575454bb3a6ac018c7ff37 316 SUPERFAMILY SSF55869 22 83 6.41E-20 T 28-03-2018 IPR035447 DNA topoisomerase I, N-terminal CNX65_RS32390 9c69b74aa66b956b9770e4385bd6906b 187 PIRSF PIRSF002161 4 187 3.5E-61 T 28-03-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32390 9c69b74aa66b956b9770e4385bd6906b 187 SUPERFAMILY SSF55282 10 185 5.42E-73 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32390 9c69b74aa66b956b9770e4385bd6906b 187 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 8 186 42.823 T 28-03-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32390 9c69b74aa66b956b9770e4385bd6906b 187 Gene3D G3DSA:3.30.1440.10 8 186 2.4E-72 T 28-03-2018 IPR022803 Ribosomal protein L5 domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32390 9c69b74aa66b956b9770e4385bd6906b 187 Pfam PF00281 Ribosomal protein L5 31 87 9.5E-25 T 28-03-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32390 9c69b74aa66b956b9770e4385bd6906b 187 Pfam PF00673 ribosomal L5P family C-terminus 91 184 1.0E-38 T 28-03-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS11015 2c9a2354f9175fe79c4146748c9f8953 342 Pfam PF02470 MlaD protein 42 116 8.0E-16 T 28-03-2018 IPR003399 Mce/MlaD CNX65_RS11015 2c9a2354f9175fe79c4146748c9f8953 342 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 15 295 6.7E-60 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS27255 3b927b259a369dd067fd116d698bb31d 64 PRINTS PR00064 Ribosomal protein L35 signature 21 35 7.3E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CNX65_RS27255 3b927b259a369dd067fd116d698bb31d 64 PRINTS PR00064 Ribosomal protein L35 signature 3 20 7.3E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CNX65_RS27255 3b927b259a369dd067fd116d698bb31d 64 PRINTS PR00064 Ribosomal protein L35 signature 36 54 7.3E-16 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CNX65_RS27255 3b927b259a369dd067fd116d698bb31d 64 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 16.81 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CNX65_RS27255 3b927b259a369dd067fd116d698bb31d 64 Pfam PF01632 Ribosomal protein L35 2 62 6.3E-23 T 28-03-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27255 3b927b259a369dd067fd116d698bb31d 64 SUPERFAMILY SSF143034 2 63 4.19E-21 T 28-03-2018 CNX65_RS27255 3b927b259a369dd067fd116d698bb31d 64 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 1.0E-22 T 28-03-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 Pfam PF10282 Lactonase, 7-bladed beta-propeller 48 326 6.9E-14 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 87 127 4.2E-12 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 261 300 2.9E-9 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 302 342 3.1E-16 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 128 160 8.2E-10 T 28-03-2018 IPR011964 YVTN beta-propeller repeat CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 Gene3D G3DSA:2.130.10.10 223 407 1.7E-27 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 SUPERFAMILY SSF50974 24 342 4.71E-65 T 28-03-2018 IPR011045 Nitrous oxide reductase, N-terminal Reactome: R-HSA-114608 CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 Gene3D G3DSA:2.130.10.10 24 132 7.0E-16 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS08720 b07e75ce691c8eac0a15bfb72c41f024 451 Gene3D G3DSA:2.130.10.10 133 222 1.0E-23 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Gene3D G3DSA:3.40.50.620 250 397 2.4E-19 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Pfam PF00582 Universal stress protein family 266 391 7.8E-11 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 SUPERFAMILY SSF52540 43 176 1.46E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 SUPERFAMILY SSF47384 634 714 6.28E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Gene3D G3DSA:3.40.50.300 37 165 2.2E-22 T 28-03-2018 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Gene3D G3DSA:1.10.287.130 630 710 1.8E-13 T 28-03-2018 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 SUPERFAMILY SSF52402 267 393 9.77E-16 T 28-03-2018 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 840 858 5.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 864 877 5.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 807 821 5.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 PRINTS PR00344 Bacterial sensor protein C-terminal signature 825 835 5.4E-11 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 759 878 2.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 37 246 5.8E-95 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 SMART SM00387 755 880 1.8E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Pfam PF13493 Domain of unknown function (DUF4118) 417 523 3.6E-25 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Gene3D G3DSA:3.30.565.10 722 883 6.8E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Pfam PF00512 His Kinase A (phospho-acceptor) domain 647 713 1.5E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 SUPERFAMILY SSF55874 703 878 2.62E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 SMART SM00388 646 714 1.1E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS09765 f3555fdb63b23b1cebd1f916e05f0bd5 884 Gene3D G3DSA:1.20.120.620 416 515 2.5E-24 T 28-03-2018 CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 Pfam PF13424 Tetratricopeptide repeat 463 531 6.1E-8 T 28-03-2018 CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 PRINTS PR00364 Disease resistance protein signature 39 54 5.5E-6 T 28-03-2018 CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 PRINTS PR00364 Disease resistance protein signature 119 133 5.5E-6 T 28-03-2018 CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 PRINTS PR00364 Disease resistance protein signature 204 218 5.5E-6 T 28-03-2018 CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 SUPERFAMILY SSF48452 462 624 1.57E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 SUPERFAMILY SSF52540 8 221 3.62E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 Gene3D G3DSA:1.25.40.10 429 635 6.3E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15200 3f443c8be1858755f9dba329dd9825a1 652 Gene3D G3DSA:3.40.50.300 9 166 3.4E-12 T 28-03-2018 CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 SUPERFAMILY SSF117074 32 122 4.84E-12 T 28-03-2018 CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 Pfam PF17210 SdrD B-like domain 161 232 5.7E-15 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 Pfam PF17210 SdrD B-like domain 39 128 1.0E-10 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 Pfam PF17210 SdrD B-like domain 256 367 2.8E-24 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 SUPERFAMILY SSF117074 241 329 6.67E-20 T 28-03-2018 CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 SUPERFAMILY SSF117074 147 233 1.07E-15 T 28-03-2018 CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 Gene3D G3DSA:2.60.40.10 436 592 8.1E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 Gene3D G3DSA:2.60.40.10 155 245 3.5E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 Gene3D G3DSA:2.60.40.10 34 149 1.0E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21005 b0d0dd095815f508ba25395a34a898f0 654 Gene3D G3DSA:2.60.40.1120 251 355 1.1E-11 T 28-03-2018 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 Gene3D G3DSA:3.30.450.40 20 193 1.5E-22 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 Gene3D G3DSA:3.30.450.40 194 352 1.5E-22 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 SUPERFAMILY SSF55781 44 189 6.54E-17 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 SUPERFAMILY SSF55781 198 358 2.4E-18 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 383 503 1.1E-32 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 Pfam PF13185 GAF domain 41 183 5.2E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 Pfam PF13185 GAF domain 211 354 5.4E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 SUPERFAMILY SSF58104 342 518 1.15E-42 T 28-03-2018 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 Gene3D G3DSA:1.10.287.950 353 520 6.3E-37 T 28-03-2018 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 SMART SM00283 316 517 5.5E-11 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 SMART SM00065 41 192 0.0024 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS01930 9a47d9091541a4a71d455bbcd12712f5 520 SMART SM00065 213 364 4.3E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS12230 8c1340d6ce51055b5f52362a68f67252 424 SUPERFAMILY SSF53850 17 423 6.92E-67 T 28-03-2018 CNX65_RS12230 8c1340d6ce51055b5f52362a68f67252 424 Gene3D G3DSA:3.40.190.10 30 199 8.3E-35 T 28-03-2018 CNX65_RS12230 8c1340d6ce51055b5f52362a68f67252 424 Pfam PF01547 Bacterial extracellular solute-binding protein 47 341 1.4E-29 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS12230 8c1340d6ce51055b5f52362a68f67252 424 Gene3D G3DSA:3.40.190.10 200 387 7.2E-11 T 28-03-2018 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Pfam PF02754 Cysteine-rich domain 670 742 0.0023 T 28-03-2018 IPR004017 Cysteine-rich domain CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Pfam PF13183 4Fe-4S dicluster domain 504 580 1.5E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Gene3D G3DSA:3.30.43.10 1 86 7.1E-20 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 SUPERFAMILY SSF46548 450 583 1.99E-8 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 SUPERFAMILY SSF55103 235 468 3.76E-47 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Pfam PF02913 FAD linked oxidases, C-terminal domain 232 465 6.8E-41 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Pfam PF01565 FAD binding domain 36 172 4.8E-38 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Gene3D G3DSA:1.10.1060.10 494 598 5.2E-17 T 28-03-2018 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 SUPERFAMILY SSF56176 2 232 7.94E-57 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Gene3D G3DSA:3.30.465.10 87 253 5.0E-42 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 566 577 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS11120 f34c350f3f0912d7cb497c38951788eb 894 Gene3D G3DSA:1.10.45.10 426 465 2.5E-10 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 Hamap MF_01393 ATP synthase subunit a [atpB]. 35 282 13.975 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 SUPERFAMILY SSF81336 107 276 4.32E-38 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 55 278 8.2E-40 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 PRINTS PR00123 ATP synthase A subunit signature 262 277 2.9E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 PRINTS PR00123 ATP synthase A subunit signature 115 131 2.9E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 PRINTS PR00123 ATP synthase A subunit signature 200 222 2.9E-16 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 Pfam PF00119 ATP synthase A chain 57 275 6.7E-51 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30225 dccde064fa5751b8066faf3f063c19f6 283 Gene3D G3DSA:1.20.120.220 55 283 9.9E-37 T 28-03-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Gene3D G3DSA:1.25.40.10 106 264 3.0E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Pfam PF00931 NB-ARC domain 291 537 7.1E-7 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 SUPERFAMILY SSF48452 99 260 1.52E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 PRINTS PR00364 Disease resistance protein signature 377 391 2.4E-5 T 28-03-2018 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 PRINTS PR00364 Disease resistance protein signature 298 313 2.4E-5 T 28-03-2018 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 PRINTS PR00364 Disease resistance protein signature 465 479 2.4E-5 T 28-03-2018 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 SUPERFAMILY SSF48452 728 876 7.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Pfam PF03704 Bacterial transcriptional activator domain 104 242 4.1E-28 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 SUPERFAMILY SSF46894 7 97 1.02E-7 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 SMART SM01043 104 245 3.2E-31 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 SUPERFAMILY SSF52540 270 533 4.16E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 97 4.5E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Pfam PF13424 Tetratricopeptide repeat 800 871 3.2E-8 T 28-03-2018 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Gene3D G3DSA:1.10.10.10 1 105 6.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 SMART SM00028 801 834 6.4E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Gene3D G3DSA:3.30.70.100 787 837 3.4E-6 T 28-03-2018 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Gene3D G3DSA:1.25.40.10 838 919 0.0034 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Gene3D G3DSA:3.40.50.300 265 428 2.6E-13 T 28-03-2018 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 Gene3D G3DSA:1.25.40.10 485 786 0.17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS22230 7e6783d2406f4321f35bd20cd7a118e5 938 SMART SM00862 21 97 9.6E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 42 60 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 178 198 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 313 332 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 108 127 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 132 148 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 60 74 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 352 370 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 149 166 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 PRINTS PR00681 Ribosomal protein S1 signature 235 256 3.4E-87 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SUPERFAMILY SSF50249 213 295 1.93E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Gene3D G3DSA:2.40.50.140 300 448 5.2E-26 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SUPERFAMILY SSF50249 34 136 4.92E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Gene3D G3DSA:2.40.50.140 126 203 3.3E-11 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SUPERFAMILY SSF50249 113 197 5.97E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Gene3D G3DSA:2.40.50.140 207 289 2.7E-27 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SUPERFAMILY SSF50249 283 371 9.9E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Gene3D G3DSA:2.40.50.140 19 116 5.1E-19 T 28-03-2018 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Pfam PF00575 S1 RNA binding domain 212 283 8.2E-26 T 28-03-2018 IPR003029 S1 domain GO:0003676 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Pfam PF00575 S1 RNA binding domain 39 111 2.2E-16 T 28-03-2018 IPR003029 S1 domain GO:0003676 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Pfam PF00575 S1 RNA binding domain 127 194 1.3E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 Pfam PF00575 S1 RNA binding domain 297 369 3.4E-24 T 28-03-2018 IPR003029 S1 domain GO:0003676 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SMART SM00316 40 111 5.1E-18 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SMART SM00316 127 194 1.6E-9 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SMART SM00316 213 283 3.3E-28 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS27500 52aed671ab48a26992dc8f3f14bd0546 495 SMART SM00316 298 369 6.9E-26 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS01830 bd1cdb3347f9e6e6d99d9d328f15e50c 93 SUPERFAMILY SSF143120 1 47 4.97E-9 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS01830 bd1cdb3347f9e6e6d99d9d328f15e50c 93 Gene3D G3DSA:3.40.1620.10 1 71 7.2E-14 T 28-03-2018 CNX65_RS01830 bd1cdb3347f9e6e6d99d9d328f15e50c 93 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 50 3.5E-8 T 28-03-2018 CNX65_RS01830 bd1cdb3347f9e6e6d99d9d328f15e50c 93 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 1 49 3.8E-9 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS11395 ef1a8d3cafad74bc66479da4d2110084 64 TIGRFAM TIGR03687 pupylate_cterm: ubiquitin-like protein Pup 33 64 2.2E-20 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CNX65_RS11395 ef1a8d3cafad74bc66479da4d2110084 64 Pfam PF05639 Pup-like protein 3 64 3.1E-22 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CNX65_RS11395 ef1a8d3cafad74bc66479da4d2110084 64 Hamap MF_02106 Prokaryotic ubiquitin-like protein Pup [pup]. 1 64 16.65 T 28-03-2018 IPR008515 Ubiquitin-like, Pup CNX65_RS11395 ef1a8d3cafad74bc66479da4d2110084 64 Gene3D G3DSA:3.40.605.10 2 64 9.7E-4 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS08305 41a19e32a4f1c5b0e495a371f62f0f51 678 Gene3D G3DSA:3.40.50.410 54 266 1.3E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS08305 41a19e32a4f1c5b0e495a371f62f0f51 678 SUPERFAMILY SSF53300 58 262 1.92E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS08305 41a19e32a4f1c5b0e495a371f62f0f51 678 Gene3D G3DSA:3.40.1850.10 345 438 1.4E-5 T 28-03-2018 CNX65_RS08305 41a19e32a4f1c5b0e495a371f62f0f51 678 Pfam PF00801 PKD domain 441 511 1.7E-5 T 28-03-2018 IPR000601 PKD domain CNX65_RS08305 41a19e32a4f1c5b0e495a371f62f0f51 678 SUPERFAMILY SSF49299 397 512 9.68E-11 T 28-03-2018 IPR000601 PKD domain CNX65_RS08305 41a19e32a4f1c5b0e495a371f62f0f51 678 Gene3D G3DSA:2.60.40.10 439 520 1.4E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 Gene3D G3DSA:3.40.50.720 1 125 6.2E-9 T 28-03-2018 CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 SUPERFAMILY SSF55347 127 196 8.72E-5 T 28-03-2018 CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 Gene3D G3DSA:3.30.360.10 126 195 1.9E-7 T 28-03-2018 CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 43 101 2.6E-4 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 PIRSF PIRSF000161 1 227 5.9E-25 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 127 219 3.0E-11 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 SUPERFAMILY SSF51735 1 103 1.73E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15900 683c74a0bc91fac07768a7949df9043b 238 SUPERFAMILY SSF51735 198 222 1.73E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27865 43516ec215b97dc680cfbd07bd281640 292 SUPERFAMILY SSF54637 12 122 1.44E-41 T 28-03-2018 IPR029069 HotDog domain CNX65_RS27865 43516ec215b97dc680cfbd07bd281640 292 Gene3D G3DSA:3.10.129.10 10 124 2.9E-44 T 28-03-2018 CNX65_RS27865 43516ec215b97dc680cfbd07bd281640 292 TIGRFAM TIGR00189 tesB: acyl-CoA thioesterase II 20 289 3.7E-92 T 28-03-2018 IPR003703 Acyl-CoA thioesterase GO:0006637|GO:0047617 Reactome: R-HSA-193368|Reactome: R-HSA-2046106|Reactome: R-HSA-389887|Reactome: R-HSA-390247 CNX65_RS27865 43516ec215b97dc680cfbd07bd281640 292 Pfam PF13622 Thioesterase-like superfamily 39 287 9.4E-64 T 28-03-2018 CNX65_RS27865 43516ec215b97dc680cfbd07bd281640 292 Gene3D G3DSA:3.10.129.10 139 292 6.6E-54 T 28-03-2018 CNX65_RS27865 43516ec215b97dc680cfbd07bd281640 292 SUPERFAMILY SSF54637 124 289 2.24E-53 T 28-03-2018 IPR029069 HotDog domain CNX65_RS22770 2f3fdb36f0c8be85c697297370186cd7 392 SUPERFAMILY SSF53383 12 385 5.85E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS22770 2f3fdb36f0c8be85c697297370186cd7 392 Gene3D G3DSA:3.40.640.10 12 253 8.6E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS22770 2f3fdb36f0c8be85c697297370186cd7 392 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 382 4.6E-127 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS22770 2f3fdb36f0c8be85c697297370186cd7 392 PIRSF PIRSF000390 8 388 1.7E-112 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS22770 2f3fdb36f0c8be85c697297370186cd7 392 Gene3D G3DSA:3.90.1150.10 254 391 1.9E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS20835 45276410eb208ce216eddc54dd9f1855 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 67 328 6.5E-30 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CNX65_RS20835 45276410eb208ce216eddc54dd9f1855 328 Gene3D G3DSA:3.40.190.10 130 323 1.5E-13 T 28-03-2018 CNX65_RS20835 45276410eb208ce216eddc54dd9f1855 328 PIRSF PIRSF017082 1 328 9.0E-97 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CNX65_RS20835 45276410eb208ce216eddc54dd9f1855 328 SUPERFAMILY SSF53850 120 282 7.82E-8 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:1.10.1200.10 1998 2071 4.7E-23 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:1.10.1200.10 1337 1501 0.16 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF52777 184 427 1.22E-47 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF47336 1987 2059 3.8E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.40.50.980 1502 1639 8.1E-39 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 986 1001 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF00501 AMP-binding enzyme 463 847 1.5E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF00501 AMP-binding enzyme 1501 1890 5.4E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF52777 1227 1472 6.67E-58 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF00668 Condensation domain 1047 1485 2.5E-94 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF00668 Condensation domain 15 432 2.5E-81 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF47336 955 1024 6.15E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.30.559.10 1029 1243 7.5E-42 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.30.559.10 11 198 1.5E-41 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2018 2033 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF56801 1501 2007 3.4E-143 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.40.50.980 460 594 2.5E-33 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 ProSitePatterns PS00455 Putative AMP-binding domain signature. 589 600 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:1.10.1200.10 968 1028 4.9E-21 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 479 870 8.1E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1515 1914 1.2E-124 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF00550 Phosphopantetheine attachment site 964 1023 5.4E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF00550 Phosphopantetheine attachment site 1997 2058 6.5E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.40.50.980 1640 1797 4.6E-38 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.40.50.980 595 755 5.7E-36 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF52777 17 178 3.34E-45 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF56801 461 975 4.32E-142 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1635 1646 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.30.300.30 842 967 5.1E-40 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:3.30.300.30 1885 1997 2.2E-33 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF13193 AMP-binding enzyme C-terminal domain 855 935 3.8E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Pfam PF13193 AMP-binding enzyme C-terminal domain 1901 1969 3.9E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:2.30.38.10 1803 1883 1.4E-21 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SMART SM00823 Phosphopantetheine attachment site 962 1031 0.021 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SMART SM00823 Phosphopantetheine attachment site 1994 2063 8.5E-6 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 SUPERFAMILY SSF52777 1049 1220 1.45E-45 T 28-03-2018 CNX65_RS18110 90b7e190d670dd319400b1599eb4e81f 2085 Gene3D G3DSA:2.30.38.10 759 837 7.0E-26 T 28-03-2018 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 Hamap MF_00942 Endonuclease III [nth]. 11 224 36.558 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 ProSitePatterns PS01155 Endonuclease III family signature. 117 146 - T 28-03-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 Gene3D G3DSA:1.10.340.30 36 133 3.2E-26 T 28-03-2018 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 Pfam PF00633 Helix-hairpin-helix motif 114 141 9.3E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 SUPERFAMILY SSF48150 22 221 1.32E-64 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 SMART SM00478 53 200 4.0E-58 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 TIGRFAM TIGR01083 nth: endonuclease III 21 209 5.2E-78 T 28-03-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 SMART SM00525 201 221 6.0E-4 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 Gene3D G3DSA:1.10.1670.10 134 235 5.3E-28 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 PIRSF PIRSF001435 17 226 1.2E-46 T 28-03-2018 CNX65_RS01205 712a162207b12090daeb6c790348c5e5 257 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 49 179 5.7E-23 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CNX65_RS20475 c2d6f3a7ef8d500dce741c7a600b0920 408 Pfam PF09594 Glycosyltransferase family 87 57 290 1.9E-41 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 360 382 4.4E-81 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 254 281 4.4E-81 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 71 100 4.4E-81 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 8 31 4.4E-81 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 124 149 4.4E-81 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 172 200 4.4E-81 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 Gene3D G3DSA:3.40.50.720 4 184 7.8E-40 T 28-03-2018 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 183 470 1.2E-124 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 Gene3D G3DSA:1.20.5.320 439 479 7.1E-17 T 28-03-2018 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 258 270 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 SUPERFAMILY SSF51735 8 181 2.73E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 SMART SM01350 183 471 5.8E-204 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 SUPERFAMILY SSF48179 181 474 1.84E-117 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 Gene3D G3DSA:1.10.1040.10 185 438 2.2E-105 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 10 471 2.8E-209 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 176 9.6E-52 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS27835 5c3e31ca42ecb1cacbd5ebf1858b99e3 479 PIRSF PIRSF000109 2 479 6.7E-205 T 28-03-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 Gene3D G3DSA:3.40.630.10 128 455 6.7E-126 T 28-03-2018 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 Gene3D G3DSA:3.40.220.10 26 118 2.1E-13 T 28-03-2018 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 303 310 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 143 447 8.9E-112 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 SUPERFAMILY SSF53187 138 451 6.91E-106 T 28-03-2018 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 PRINTS PR00481 Cytosol aminopeptidase signature 218 235 1.4E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 PRINTS PR00481 Cytosol aminopeptidase signature 240 261 1.4E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 PRINTS PR00481 Cytosol aminopeptidase signature 299 319 1.4E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 PRINTS PR00481 Cytosol aminopeptidase signature 328 343 1.4E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 PRINTS PR00481 Cytosol aminopeptidase signature 277 298 1.4E-48 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS03895 a256ba3972916e9246d8dc58a05158d1 455 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 8 455 29.532 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 Pfam PF13183 4Fe-4S dicluster domain 311 377 2.7E-7 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 Gene3D G3DSA:3.30.70.20 292 320 0.024 T 28-03-2018 CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 Gene3D G3DSA:3.40.50.10420 67 148 2.9E-10 T 28-03-2018 CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 Gene3D G3DSA:3.40.50.10420 149 291 2.6E-38 T 28-03-2018 CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 Pfam PF11870 Domain of unknown function (DUF3390) 398 467 6.8E-11 T 28-03-2018 IPR024569 4Fe-4S binding protein, C-terminal CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 SUPERFAMILY SSF46548 288 392 8.37E-14 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 SUPERFAMILY SSF100950 138 295 3.26E-33 T 28-03-2018 CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 SUPERFAMILY SSF100950 68 92 3.26E-33 T 28-03-2018 CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 Pfam PF02589 LUD domain 75 291 1.8E-49 T 28-03-2018 IPR003741 LUD domain CNX65_RS15415 3f9635abd3421e724d907b27f33ddb70 467 Gene3D G3DSA:3.30.70.20 321 383 1.9E-7 T 28-03-2018 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 SUPERFAMILY SSF55931 105 473 2.55E-139 T 28-03-2018 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 SUPERFAMILY SSF54368 5 102 1.83E-31 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 390 402 - T 28-03-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 261 276 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 Gene3D G3DSA:3.10.20.70 4 106 6.1E-26 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 473 1.8E-206 T 28-03-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 Gene3D G3DSA:3.30.590.10 107 460 1.1E-125 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 97 9.7E-25 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 28-03-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 Pfam PF00120 Glutamine synthetase, catalytic domain 105 471 1.0E-136 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04530 c583117ba57cd3569324a85e1017f076 474 SMART SM01230 104 383 6.7E-152 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS08635 ecb1ea80fdc587b0cfc38d7719ee354a 467 Gene3D G3DSA:3.40.50.720 139 261 2.6E-14 T 28-03-2018 CNX65_RS08635 ecb1ea80fdc587b0cfc38d7719ee354a 467 TIGRFAM TIGR03025 EPS_sugtrans: exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase 15 467 2.4E-119 T 28-03-2018 IPR017475 Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase CNX65_RS08635 ecb1ea80fdc587b0cfc38d7719ee354a 467 Pfam PF13727 CoA-binding domain 76 208 3.4E-6 T 28-03-2018 CNX65_RS08635 ecb1ea80fdc587b0cfc38d7719ee354a 467 Pfam PF02397 Bacterial sugar transferase 274 461 1.1E-64 T 28-03-2018 IPR003362 Bacterial sugar transferase CNX65_RS12095 e202c8809c3e64e63ae8a70f75f34248 170 Gene3D G3DSA:1.10.10.10 10 157 4.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12095 e202c8809c3e64e63ae8a70f75f34248 170 Pfam PF12802 MarR family 44 103 6.6E-8 T 28-03-2018 CNX65_RS12095 e202c8809c3e64e63ae8a70f75f34248 170 SUPERFAMILY SSF46785 12 155 6.12E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12095 e202c8809c3e64e63ae8a70f75f34248 170 SMART SM00347 38 141 7.5E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS16510 7e753ba37ef916877aeb010390725bbb 336 Gene3D G3DSA:3.40.50.620 154 295 1.1E-34 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS16510 7e753ba37ef916877aeb010390725bbb 336 Pfam PF02698 DUF218 domain 163 308 3.4E-33 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CNX65_RS21210 489a0ab2c3600ebf1dd8ce90a6a90bd1 113 Gene3D G3DSA:2.30.110.10 1 70 5.4E-9 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS21210 489a0ab2c3600ebf1dd8ce90a6a90bd1 113 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 64 1.3E-5 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS21210 489a0ab2c3600ebf1dd8ce90a6a90bd1 113 Gene3D G3DSA:2.30.110.10 71 112 0.022 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS21210 489a0ab2c3600ebf1dd8ce90a6a90bd1 113 SUPERFAMILY SSF50475 10 109 6.87E-15 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 PRINTS PR01755 Bacterial translocase SecF protein signature 577 591 2.9E-21 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 PRINTS PR01755 Bacterial translocase SecF protein signature 657 672 2.9E-21 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 PRINTS PR01755 Bacterial translocase SecF protein signature 469 484 2.9E-21 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 PRINTS PR01755 Bacterial translocase SecF protein signature 625 643 2.9E-21 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Gene3D G3DSA:1.20.1640.10 211 416 6.2E-27 T 28-03-2018 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 470 707 4.1E-53 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 442 720 23.99 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 35 411 2.5E-99 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Gene3D G3DSA:1.20.1640.10 486 731 6.1E-25 T 28-03-2018 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 7 426 35.229 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Pfam PF07549 SecD/SecF GG Motif 26 48 2.2E-4 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Pfam PF07549 SecD/SecF GG Motif 466 487 5.1E-5 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 189 404 1.2E-60 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 SUPERFAMILY SSF82866 221 417 5.75E-37 T 28-03-2018 CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Pfam PF02355 Protein export membrane protein 246 411 1.2E-10 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 Pfam PF02355 Protein export membrane protein 542 716 7.2E-53 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CNX65_RS05385 de102cb01f723ca00ecf23fa68538f2b 749 SUPERFAMILY SSF82866 528 719 2.09E-27 T 28-03-2018 CNX65_RS03530 0e5ae20adda29d0b1c15d35577774881 293 SUPERFAMILY SSF102588 4 288 7.46E-78 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS03530 0e5ae20adda29d0b1c15d35577774881 293 Hamap MF_01482 Mycothiol S-conjugate amidase [mca]. 8 288 55.316 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CNX65_RS03530 0e5ae20adda29d0b1c15d35577774881 293 Pfam PF02585 GlcNAc-PI de-N-acetylase 8 153 1.3E-27 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CNX65_RS03530 0e5ae20adda29d0b1c15d35577774881 293 Gene3D G3DSA:3.40.50.10320 1 293 8.2E-81 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS03530 0e5ae20adda29d0b1c15d35577774881 293 TIGRFAM TIGR03446 mycothiol_Mca: mycothiol conjugate amidase Mca 5 287 5.9E-153 T 28-03-2018 IPR017811 Mycothiol S-conjugate amidase Mca GO:0010126 KEGG: 00311+3.5.1.11 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Gene3D G3DSA:3.40.50.300 450 625 6.7E-23 T 28-03-2018 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Pfam PF00005 ABC transporter 634 870 2.2E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 ProSitePatterns PS00211 ABC transporters family signature. 840 854 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 5 935 0.0 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 SUPERFAMILY SSF52540 441 580 1.84E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 SUPERFAMILY SSF52540 10 205 1.84E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Gene3D G3DSA:3.40.50.300 5 36 0.0031 T 28-03-2018 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Hamap MF_00205 UvrABC system protein A [uvrA]. 2 950 22.731 T 28-03-2018 IPR004602 UvrABC system subunit A GO:0006289|GO:0009380|GO:0009381 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Gene3D G3DSA:3.40.50.300 626 951 2.6E-53 T 28-03-2018 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Gene3D G3DSA:1.10.8.280 290 411 4.5E-37 T 28-03-2018 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Gene3D G3DSA:3.40.50.300 37 81 0.0019 T 28-03-2018 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 SUPERFAMILY SSF52540 625 919 1.36E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27310 1a976770dba4347a2764f3811a974ec7 952 Gene3D G3DSA:3.30.190.20 128 244 2.2E-40 T 28-03-2018 CNX65_RS24255 f51eda9b66dcf2fab67ed5790892665b 549 SUPERFAMILY SSF81606 325 528 1.99E-5 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24255 f51eda9b66dcf2fab67ed5790892665b 549 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 340 529 6.7E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24255 f51eda9b66dcf2fab67ed5790892665b 549 Gene3D G3DSA:3.60.40.10 290 530 5.0E-35 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24255 f51eda9b66dcf2fab67ed5790892665b 549 SMART SM00065 128 291 0.0021 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS24255 f51eda9b66dcf2fab67ed5790892665b 549 Gene3D G3DSA:3.30.450.40 110 289 1.2E-23 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS24255 f51eda9b66dcf2fab67ed5790892665b 549 SUPERFAMILY SSF55781 147 290 4.14E-11 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS24255 f51eda9b66dcf2fab67ed5790892665b 549 SMART SM00331 309 530 2.1E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 SUPERFAMILY SSF52518 365 557 1.69E-65 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 SUPERFAMILY SSF52922 564 696 1.57E-41 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 TIGRFAM TIGR00232 tktlase_bact: transketolase 25 693 6.1E-243 T 28-03-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 Gene3D G3DSA:3.40.50.920 569 694 3.9E-32 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 Gene3D G3DSA:3.40.50.970 4 369 8.2E-89 T 28-03-2018 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 Pfam PF02779 Transketolase, pyrimidine binding domain 374 554 5.4E-46 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 SMART SM00861 375 555 2.1E-66 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 Pfam PF02780 Transketolase, C-terminal domain 581 687 8.4E-13 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 Gene3D G3DSA:3.40.50.970 370 565 1.6E-47 T 28-03-2018 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 ProSitePatterns PS00801 Transketolase signature 1. 31 51 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 SUPERFAMILY SSF52518 17 344 7.94E-100 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 ProSitePatterns PS00802 Transketolase signature 2. 497 513 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS25795 19414339f624c78b3de4663ca64a44f3 699 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 23 358 3.9E-137 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS02585 8b87c328fb760e7f8d87e875f5253734 100 ProDom PD002319 SUBUNIT GAMMA HYDROLASE UREASE UREA AMIDOHYDROLASE UREASE ALPHA GAMMA/BETA METAL-BINDING 9 99 2.0E-35 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02585 8b87c328fb760e7f8d87e875f5253734 100 Pfam PF00547 Urease, gamma subunit 1 99 3.9E-47 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02585 8b87c328fb760e7f8d87e875f5253734 100 Hamap MF_00739 Urease subunit gamma [ureA]. 1 100 33.927 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02585 8b87c328fb760e7f8d87e875f5253734 100 PIRSF PIRSF001223 1 100 8.1E-51 T 28-03-2018 IPR012010 Urease, gamma subunit GO:0009039|GO:0019627 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02585 8b87c328fb760e7f8d87e875f5253734 100 Gene3D G3DSA:3.30.280.10 2 99 1.2E-47 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02585 8b87c328fb760e7f8d87e875f5253734 100 TIGRFAM TIGR00193 urease_gam: urease, gamma subunit 1 100 3.8E-48 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02585 8b87c328fb760e7f8d87e875f5253734 100 SUPERFAMILY SSF54111 1 99 9.68E-45 T 28-03-2018 IPR002026 Urease, gamma/gamma-beta subunit GO:0016151|GO:0043419 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS09740 47b76e2e7e7d75f3462e3faf7fc20f7e 264 PIRSF PIRSF004846 3 264 2.6E-62 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CNX65_RS09740 47b76e2e7e7d75f3462e3faf7fc20f7e 264 Gene3D G3DSA:3.40.190.10 215 262 9.9E-4 T 28-03-2018 CNX65_RS09740 47b76e2e7e7d75f3462e3faf7fc20f7e 264 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 49 258 1.4E-36 T 28-03-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689|GO:0030288 CNX65_RS09740 47b76e2e7e7d75f3462e3faf7fc20f7e 264 Gene3D G3DSA:3.40.190.10 133 214 1.1E-20 T 28-03-2018 CNX65_RS09740 47b76e2e7e7d75f3462e3faf7fc20f7e 264 SUPERFAMILY SSF53850 43 263 2.48E-49 T 28-03-2018 CNX65_RS09740 47b76e2e7e7d75f3462e3faf7fc20f7e 264 Pfam PF13531 Bacterial extracellular solute-binding protein 44 261 7.2E-41 T 28-03-2018 CNX65_RS09740 47b76e2e7e7d75f3462e3faf7fc20f7e 264 Gene3D G3DSA:3.40.190.10 41 132 5.1E-18 T 28-03-2018 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 437 451 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 521 538 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 541 553 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 115 129 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 37 52 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 285 298 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 72 85 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 503 519 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR00418 DNA topoisomerase II family signature 589 605 1.3E-69 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Gene3D G3DSA:3.30.565.10 18 241 1.0E-70 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 SMART SM00433 37 650 0.0 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 5 657 91.757 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 35 175 3.0E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Pfam PF00204 DNA gyrase B 238 407 1.0E-62 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Gene3D G3DSA:3.30.230.10 242 409 1.5E-64 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 SUPERFAMILY SSF55874 8 212 1.78E-68 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 197 210 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 626 642 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 237 259 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 377 391 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 182 197 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 8 18 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 610 622 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 329 345 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 487 496 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 PRINTS PR01159 DNA gyrase subunit B signature 391 411 2.0E-70 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 SUPERFAMILY SSF56719 411 651 8.37E-84 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 SMART SM00387 33 177 6.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 8 657 2.1E-292 T 28-03-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Pfam PF01751 Toprim domain 436 547 4.1E-16 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Gene3D G3DSA:3.40.50.670 419 654 2.4E-97 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 588 645 1.7E-28 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 SUPERFAMILY SSF54211 238 408 6.83E-60 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS00030 1cac1a59adca251f42ae5979095cb935 657 ProSitePatterns PS00177 DNA topoisomerase II signature. 439 447 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS20290 1e813772573dd22258c4d2ad903f8fb1 324 Pfam PF08279 HTH domain 5 57 5.1E-14 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CNX65_RS20290 1e813772573dd22258c4d2ad903f8fb1 324 Gene3D G3DSA:2.30.30.400 145 218 8.7E-4 T 28-03-2018 CNX65_RS20290 1e813772573dd22258c4d2ad903f8fb1 324 Gene3D G3DSA:1.10.10.10 2 62 2.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20290 1e813772573dd22258c4d2ad903f8fb1 324 PIRSF PIRSF016838 1 320 2.1E-22 T 28-03-2018 IPR028349 Protein PafC CNX65_RS20290 1e813772573dd22258c4d2ad903f8fb1 324 Pfam PF13280 WYL domain 141 310 3.1E-32 T 28-03-2018 IPR026881 WYL domain CNX65_RS20290 1e813772573dd22258c4d2ad903f8fb1 324 SUPERFAMILY SSF46785 3 56 1.61E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16675 64759d978f14e124f14404593924561f 173 ProSitePatterns PS00893 Nudix box signature. 55 76 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS16675 64759d978f14e124f14404593924561f 173 Gene3D G3DSA:3.90.79.10 9 166 1.6E-22 T 28-03-2018 CNX65_RS16675 64759d978f14e124f14404593924561f 173 Pfam PF00293 NUDIX domain 24 146 4.7E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS16675 64759d978f14e124f14404593924561f 173 SUPERFAMILY SSF55811 22 145 3.25E-24 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS16675 64759d978f14e124f14404593924561f 173 PRINTS PR00502 NUDIX hydrolase family signature 50 64 2.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS16675 64759d978f14e124f14404593924561f 173 PRINTS PR00502 NUDIX hydrolase family signature 64 79 2.8E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS07240 810d34c72113f083e523cb15aeb411ee 336 Pfam PF13830 Domain of unknown function (DUF4192) 14 321 1.5E-74 T 28-03-2018 IPR025447 Protein of unknown function DUF4192 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 Gene3D G3DSA:3.40.50.2020 6 161 4.1E-59 T 28-03-2018 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 Pfam PF14572 Phosphoribosyl synthetase-associated domain 213 319 2.7E-15 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 Gene3D G3DSA:3.40.50.2020 162 290 2.0E-35 T 28-03-2018 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 SMART SM01400 9 125 3.0E-68 T 28-03-2018 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 133 148 - T 28-03-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 10 320 3.5E-112 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 125 1.0E-42 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 SUPERFAMILY SSF53271 74 311 5.59E-58 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS03250 aa1c4530a908463d4e602a98fec783ec 323 Hamap MF_00583_B Ribose-phosphate pyrophosphokinase [prs]. 9 320 44.086 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CNX65_RS05425 84a52015ebb310cbb4bdb0b399e26b62 307 Pfam PF01619 Proline dehydrogenase 51 298 1.7E-31 T 28-03-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 CNX65_RS05425 84a52015ebb310cbb4bdb0b399e26b62 307 SUPERFAMILY SSF51730 35 302 4.32E-71 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CNX65_RS05425 84a52015ebb310cbb4bdb0b399e26b62 307 Gene3D G3DSA:3.20.20.220 3 306 5.4E-72 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CNX65_RS05425 84a52015ebb310cbb4bdb0b399e26b62 307 PIRSF PIRSF000196 1 307 4.5E-110 T 28-03-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 267 425 3.6E-20 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 Gene3D G3DSA:3.20.20.450 438 613 3.2E-21 T 28-03-2018 IPR001633 EAL domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 Pfam PF13188 PAS domain 157 200 3.2E-5 T 28-03-2018 IPR000014 PAS domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 SUPERFAMILY SSF141868 447 605 1.7E-10 T 28-03-2018 IPR001633 EAL domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 SUPERFAMILY SSF55785 145 258 3.14E-13 T 28-03-2018 IPR000014 PAS domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 Gene3D G3DSA:3.30.450.20 152 282 2.1E-20 T 28-03-2018 CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 Pfam PF00563 EAL domain 447 607 1.3E-11 T 28-03-2018 IPR001633 EAL domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 SMART SM00086 218 260 0.0014 T 28-03-2018 IPR001610 PAC motif CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 SUPERFAMILY SSF55073 276 430 3.53E-28 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 SMART SM00267 260 429 2.8E-30 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 Pfam PF00990 Diguanylate cyclase, GGDEF domain 271 424 1.6E-24 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS26960 6a36f0c7d9ef29b63d46a6ec493bda04 651 Gene3D G3DSA:3.30.70.270 283 437 6.2E-39 T 28-03-2018 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 Pfam PF13353 4Fe-4S single cluster domain 29 143 1.1E-16 T 28-03-2018 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 SUPERFAMILY SSF102114 34 224 9.55E-31 T 28-03-2018 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 Pfam PF04055 Radical SAM superfamily 37 189 9.9E-29 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 ProSitePatterns PS01087 Radical activating enzymes signature. 31 52 - T 28-03-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 PIRSF PIRSF000371 25 63 6.7E-12 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 PIRSF PIRSF000371 57 254 6.2E-43 T 28-03-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 20 250 1.8E-89 T 28-03-2018 IPR012838 Pyruvate formate-lyase activating enzyme GO:0043365|GO:0055114 CNX65_RS12280 974454776a5e7958a6f547c6541f69f3 255 Gene3D G3DSA:3.20.20.70 27 253 8.9E-35 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 TIGRFAM TIGR00277 HDIG: HDIG domain 250 332 3.1E-17 T 28-03-2018 IPR006675 HDIG domain CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 Gene3D G3DSA:1.10.3090.10 151 461 8.3E-68 T 28-03-2018 CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 Pfam PF01743 Poly A polymerase head domain 24 149 2.9E-31 T 28-03-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 SUPERFAMILY SSF81301 9 146 7.44E-33 T 28-03-2018 CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 Gene3D G3DSA:3.30.460.10 7 150 9.3E-41 T 28-03-2018 CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 178 239 3.1E-17 T 28-03-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 SMART SM00471 249 413 2.7E-4 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 TIGRFAM TIGR02692 tRNA_CCA_actino: CCA tRNA nucleotidyltransferase 5 460 2.3E-234 T 28-03-2018 IPR014065 tRNA adenylyltransferase CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 Pfam PF01966 HD domain 253 377 9.3E-16 T 28-03-2018 IPR006674 HD domain CNX65_RS34965 71bdd5a0208ca62c17e98086314c71b6 502 SUPERFAMILY SSF81891 150 458 1.57E-62 T 28-03-2018 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 Gene3D G3DSA:2.60.120.180 40 233 5.1E-80 T 28-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 ProSitePatterns PS00777 Glycosyl hydrolases family 11 (GH11) active site signature 2. 217 228 - T 28-03-2018 IPR033119 Glycoside hydrolase family 11, active site 2 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 ProSitePatterns PS00776 Glycosyl hydrolases family 11 (GH11) active site signature 1. 126 136 - T 28-03-2018 IPR018208 Glycoside hydrolase family 11, active site 1 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 PRINTS PR00911 Glycosyl hydrolase family 11 signature 126 136 6.9E-17 T 28-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 PRINTS PR00911 Glycosyl hydrolase family 11 signature 201 209 6.9E-17 T 28-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 PRINTS PR00911 Glycosyl hydrolase family 11 signature 152 158 6.9E-17 T 28-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 PRINTS PR00911 Glycosyl hydrolase family 11 signature 116 125 6.9E-17 T 28-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 PRINTS PR00911 Glycosyl hydrolase family 11 signature 173 178 6.9E-17 T 28-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 PRINTS PR00911 Glycosyl hydrolase family 11 signature 178 187 6.9E-17 T 28-03-2018 IPR001137 Glycoside hydrolase family 11 GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 SUPERFAMILY SSF49899 44 233 2.43E-75 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS21230 54d25702ad629a29b78a9946cc634d03 233 Pfam PF00457 Glycosyl hydrolases family 11 54 230 2.1E-71 T 28-03-2018 IPR033123 Glycosyl hydrolases family 11 (GH11) domain MetaCyc: PWY-6784 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 Pfam PF01996 F420-0:Gamma-glutamyl ligase 22 221 2.6E-38 T 28-03-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 Pfam PF00881 Nitroreductase family 262 428 4.9E-26 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 Gene3D G3DSA:3.40.109.10 255 440 2.2E-32 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 TIGRFAM TIGR03553 F420_FbiB_CTERM: F420 biosynthesis protein FbiB, C-terminal domain 257 440 2.2E-90 T 28-03-2018 IPR019943 Coenzyme F420 biosynthesis protein FbiB, C-terminal GO:0016881 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 15 244 4.0E-77 T 28-03-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 Gene3D G3DSA:3.30.1330.100 9 122 3.3E-26 T 28-03-2018 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 Gene3D G3DSA:3.30.1330.100 123 229 1.4E-26 T 28-03-2018 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 Hamap MF_01259 Coenzyme F420:L-glutamate ligase [fbiB]. 19 446 50.591 T 28-03-2018 IPR023661 Coenzyme F420:L-glutamate ligase, bacteria GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 SUPERFAMILY SSF144010 15 249 4.84E-65 T 28-03-2018 CNX65_RS31165 f60e9d1582f6ad48c13ad2d430bf259d 446 SUPERFAMILY SSF55469 257 437 1.83E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS29625 e6ed127148f86dbea92f9c8297a791c2 139 Pfam PF07884 Vitamin K epoxide reductase family 8 129 2.2E-26 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CNX65_RS29625 e6ed127148f86dbea92f9c8297a791c2 139 SMART SM00756 2 135 1.9E-25 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 179 2.2E-74 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 Gene3D G3DSA:3.40.50.720 9 47 0.011 T 28-03-2018 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 Gene3D G3DSA:1.10.1040.10 57 332 3.2E-117 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 1.4E-64 T 28-03-2018 IPR000506 Acetohydroxy acid isomeroreductase C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 SUPERFAMILY SSF51735 4 184 7.33E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 16 328 3.2E-131 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 3 330 45.305 T 28-03-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 SUPERFAMILY SSF48179 185 330 8.33E-69 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 PIRSF PIRSF000116 204 332 9.3E-15 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CNX65_RS29605 dc6f9cade48c24a17f3e4c3d542edcac 337 PIRSF PIRSF000116 4 208 3.5E-41 T 28-03-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CNX65_RS11130 6f5eed51cf6af2e41d6335ec608707f5 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 15 251 7.3E-70 T 28-03-2018 CNX65_RS11130 6f5eed51cf6af2e41d6335ec608707f5 255 SUPERFAMILY SSF51735 6 252 1.13E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS11130 6f5eed51cf6af2e41d6335ec608707f5 255 PIRSF PIRSF000094 2 255 3.7E-89 T 28-03-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 CNX65_RS11130 6f5eed51cf6af2e41d6335ec608707f5 255 Gene3D G3DSA:3.40.50.720 3 253 3.8E-40 T 28-03-2018 CNX65_RS32095 c18114450bbcfe25d4812759646331ca 309 SUPERFAMILY SSF46955 4 70 5.04E-10 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS32095 c18114450bbcfe25d4812759646331ca 309 Gene3D G3DSA:1.10.1660.10 1 182 1.5E-12 T 28-03-2018 CNX65_RS32095 c18114450bbcfe25d4812759646331ca 309 Pfam PF13411 MerR HTH family regulatory protein 5 69 4.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS32095 c18114450bbcfe25d4812759646331ca 309 SMART SM00422 4 73 0.0012 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS32095 c18114450bbcfe25d4812759646331ca 309 Gene3D G3DSA:3.40.50.280 187 307 4.5E-15 T 28-03-2018 CNX65_RS32095 c18114450bbcfe25d4812759646331ca 309 SUPERFAMILY SSF52242 190 285 2.04E-8 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 Pfam PF00082 Subtilase family 149 379 8.5E-26 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 Gene3D G3DSA:3.40.50.200 119 393 1.3E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 Gene3D G3DSA:3.30.70.80 36 118 2.1E-16 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 Pfam PF05922 Peptidase inhibitor I9 44 111 3.9E-6 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 342 352 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 SUPERFAMILY SSF52743 123 390 1.7E-65 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 152 163 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 SUPERFAMILY SSF54897 42 114 1.7E-10 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 PRINTS PR00723 Subtilisin serine protease family (S8) signature 185 198 9.6E-14 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 PRINTS PR00723 Subtilisin serine protease family (S8) signature 341 357 9.6E-14 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08560 4f9edb7612894eeb8fa5eb3c3e59ab8a 400 PRINTS PR00723 Subtilisin serine protease family (S8) signature 147 166 9.6E-14 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 PRINTS PR01035 Tetracycline resistance protein signature 161 181 1.3E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 PRINTS PR01035 Tetracycline resistance protein signature 19 35 1.3E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 PRINTS PR01035 Tetracycline resistance protein signature 133 155 1.3E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 PRINTS PR01035 Tetracycline resistance protein signature 286 307 1.3E-11 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 Gene3D G3DSA:1.20.1250.20 192 371 7.8E-17 T 28-03-2018 CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 Pfam PF07690 Major Facilitator Superfamily 14 339 1.8E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 Gene3D G3DSA:1.20.1250.20 3 189 1.7E-23 T 28-03-2018 CNX65_RS34725 1af30f8a3d3188f2d6c7874aeea84993 386 SUPERFAMILY SSF103473 1 367 6.67E-53 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 Gene3D G3DSA:1.20.1560.10 28 346 1.3E-32 T 28-03-2018 CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 SMART SM00382 386 572 1.3E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 Gene3D G3DSA:3.40.50.300 347 599 1.5E-71 T 28-03-2018 CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 Pfam PF00664 ABC transporter transmembrane region 52 244 1.0E-17 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 SUPERFAMILY SSF52540 354 596 8.58E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 Pfam PF00005 ABC transporter 379 526 2.1E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 ProSitePatterns PS00211 ABC transporters family signature. 498 512 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS18505 3616740aa4446cfe457428248525ce0b 609 SUPERFAMILY SSF90123 37 351 3.66E-33 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 30 140 1.6E-8 T 28-03-2018 CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 PRINTS PR00775 90kDa heat shock protein signature 1 21 4.8E-12 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 PRINTS PR00775 90kDa heat shock protein signature 22 44 4.8E-12 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 PRINTS PR00775 90kDa heat shock protein signature 104 126 4.8E-12 T 28-03-2018 IPR020575 Heat shock protein Hsp90, N-terminal CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 PIRSF PIRSF002583 1 208 9.7E-53 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 PIRSF PIRSF002583 210 585 1.4E-35 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 Pfam PF00183 Hsp90 protein 254 366 1.6E-9 T 28-03-2018 IPR001404 Heat shock protein Hsp90 family GO:0005524|GO:0006457|GO:0006950|GO:0051082 CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 Gene3D G3DSA:3.30.565.10 1 205 1.3E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 SUPERFAMILY SSF55874 3 197 4.19E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27225 a0cccd4afbb1ae8eb6f4419bfa9bb484 585 SUPERFAMILY SSF54211 222 420 3.72E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS15700 785f036ea27a5bc3a72cb31077aa24ba 214 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 8 178 2.7E-18 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS15700 785f036ea27a5bc3a72cb31077aa24ba 214 Pfam PF13419 Haloacid dehalogenase-like hydrolase 9 177 5.2E-14 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS15700 785f036ea27a5bc3a72cb31077aa24ba 214 SUPERFAMILY SSF56784 7 199 1.14E-39 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS15700 785f036ea27a5bc3a72cb31077aa24ba 214 Gene3D G3DSA:1.10.150.240 23 71 7.6E-14 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CNX65_RS15700 785f036ea27a5bc3a72cb31077aa24ba 214 Gene3D G3DSA:3.40.50.1000 72 203 4.6E-21 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 Pfam PF08281 Sigma-70, region 4 145 195 1.3E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 Gene3D G3DSA:1.10.1740.10 20 99 1.4E-22 T 28-03-2018 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 SUPERFAMILY SSF88946 29 117 8.83E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 58 89 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 41 199 3.7E-27 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 SUPERFAMILY SSF88659 140 199 3.92E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 TIGRFAM TIGR02947 SigH_actino: RNA polymerase sigma-70 factor, TIGR02947 family 23 210 7.5E-109 T 28-03-2018 IPR014293 RNA polymerase sigma-70, actinobacteria GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 Pfam PF04542 Sigma-70 region 2 41 103 3.3E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30995 ed90fabf019ce7b2d8c1ce85195c9623 219 Gene3D G3DSA:1.10.10.10 100 206 5.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 767 854 2.5E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF51735 1334 1505 4.72E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SMART SM00825 Beta-ketoacyl synthase 379 812 1.3E-148 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Pfam PF08659 KR domain 1518 1690 1.0E-44 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:3.40.50.720 1510 1731 1.6E-33 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Pfam PF00698 Acyl transferase domain 910 1187 1.8E-39 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF52151 908 1032 2.04E-52 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF52151 1095 1195 2.04E-52 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1789 1804 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:3.40.47.10 377 648 5.5E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:3.40.47.10 652 810 1.9E-50 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF51735 1517 1698 1.22E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:1.10.1200.10 1740 1840 1.6E-16 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SMART SM00823 Phosphopantetheine attachment site 1763 1834 1.1E-15 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SMART SM00823 Phosphopantetheine attachment site 275 345 7.0E-15 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1518 1692 1.9E-26 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Pfam PF00550 Phosphopantetheine attachment site 277 341 8.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Pfam PF00550 Phosphopantetheine attachment site 1765 1830 5.5E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF53901 787 808 8.48E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF53901 375 494 8.48E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF53901 532 756 8.48E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:3.40.50.720 1338 1500 0.0026 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:3.40.366.10 1087 1200 4.0E-15 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SMART SM01294 1764 1830 1.9E-7 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF47336 1761 1835 9.29E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:1.10.1200.10 270 376 1.7E-20 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF47336 273 391 1.24E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 644 759 1.0E-36 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:3.40.366.10 907 1044 1.8E-34 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 549 565 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 379 636 6.2E-64 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 911 1200 6.7E-61 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 Gene3D G3DSA:3.30.70.250 1045 1086 8.0E-14 T 28-03-2018 CNX65_RS17035 4940b6d570c4d4da61d1ca6417547e41 1844 SUPERFAMILY SSF55048 1031 1084 9.16E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS21625 08cda5c4b68df0faca938b1c5f296932 117 SUPERFAMILY SSF53706 2 113 1.09E-18 T 28-03-2018 CNX65_RS21625 08cda5c4b68df0faca938b1c5f296932 117 Gene3D G3DSA:3.40.50.740 42 116 4.5E-16 T 28-03-2018 CNX65_RS21625 08cda5c4b68df0faca938b1c5f296932 117 Pfam PF00384 Molybdopterin oxidoreductase 49 102 1.4E-7 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 SUPERFAMILY SSF48264 11 386 1.96E-80 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 Gene3D G3DSA:1.10.630.10 11 389 2.9E-64 T 28-03-2018 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 328 337 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 86 97 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 307 322 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 279 306 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 149 164 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 184 206 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 132 148 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 337 348 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 PRINTS PR00359 B-class P450 signature 261 272 1.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10780 bf4860527432435f042c1f87ee19ec31 389 Pfam PF00067 Cytochrome P450 213 368 3.1E-13 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 Pfam PF13377 Periplasmic binding protein-like domain 180 333 1.5E-23 T 28-03-2018 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 Gene3D G3DSA:1.10.10.60 2 21 2.7E-4 T 28-03-2018 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 Gene3D G3DSA:1.10.260.40 22 65 1.2E-20 T 28-03-2018 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 SUPERFAMILY SSF53822 82 324 1.8E-38 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 SUPERFAMILY SSF47413 7 62 1.86E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 SMART SM00354 8 78 3.1E-18 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 Gene3D G3DSA:3.40.50.2300 178 336 1.2E-23 T 28-03-2018 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 4.2E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS22910 6c86ab2f21618387157c9c23680a1355 344 Gene3D G3DSA:3.40.50.2300 66 177 2.4E-19 T 28-03-2018 CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 SUPERFAMILY SSF88946 4 98 4.51E-17 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 162 2.9E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 Gene3D G3DSA:1.10.10.10 82 168 1.0E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 166 1.8E-43 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 Pfam PF08281 Sigma-70, region 4 111 161 1.3E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 SUPERFAMILY SSF88659 105 165 8.41E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 Gene3D G3DSA:1.10.1740.10 1 81 2.3E-16 T 28-03-2018 CNX65_RS34055 59f77f24ab86feb8e5d9675e07074ef9 175 Pfam PF04542 Sigma-70 region 2 16 79 1.5E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14055 10db158ce951fbc41004be5ce14f3a0a 317 Gene3D G3DSA:3.20.20.30 1 316 4.6E-50 T 28-03-2018 CNX65_RS14055 10db158ce951fbc41004be5ce14f3a0a 317 SUPERFAMILY SSF51679 6 308 2.36E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS14055 10db158ce951fbc41004be5ce14f3a0a 317 Pfam PF00296 Luciferase-like monooxygenase 17 295 1.1E-41 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 SUPERFAMILY SSF117074 59 128 1.22E-9 T 28-03-2018 CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 SMART SM00458 178 319 2.0E-6 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 Gene3D G3DSA:2.80.10.50 281 320 4.9E-5 T 28-03-2018 CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 SUPERFAMILY SSF50370 183 317 6.68E-19 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 Pfam PF17210 SdrD B-like domain 62 174 3.8E-11 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 Gene3D G3DSA:2.60.40.1120 57 148 1.7E-7 T 28-03-2018 CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 Pfam PF00652 Ricin-type beta-trefoil lectin domain 184 316 2.3E-14 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20760 bc5e2f03b15e88065a898be02f01690d 320 Gene3D G3DSA:2.80.10.50 176 280 1.5E-12 T 28-03-2018 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 SUPERFAMILY SSF48264 23 367 9.3E-47 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 PRINTS PR00359 B-class P450 signature 126 142 4.8E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 PRINTS PR00359 B-class P450 signature 176 198 4.8E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 PRINTS PR00359 B-class P450 signature 272 299 4.8E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 PRINTS PR00359 B-class P450 signature 253 264 4.8E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 PRINTS PR00359 B-class P450 signature 143 158 4.8E-25 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 Gene3D G3DSA:1.10.630.10 309 367 0.0016 T 28-03-2018 CNX65_RS12625 d9ab14e7fa42d793b55f692a4fb2bcf0 367 Gene3D G3DSA:1.10.630.10 22 297 1.2E-26 T 28-03-2018 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 PRINTS PR00133 Glycosyl hydrolase family 3 signature 334 352 7.9E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 PRINTS PR00133 Glycosyl hydrolase family 3 signature 218 234 7.9E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 PRINTS PR00133 Glycosyl hydrolase family 3 signature 257 273 7.9E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 PRINTS PR00133 Glycosyl hydrolase family 3 signature 148 164 7.9E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 PRINTS PR00133 Glycosyl hydrolase family 3 signature 172 191 7.9E-22 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 85 411 1.0E-75 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 Gene3D G3DSA:2.60.120.430 684 862 1.3E-19 T 28-03-2018 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 SUPERFAMILY SSF51445 69 447 2.53E-104 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 SUPERFAMILY SSF52279 449 659 1.44E-39 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 Gene3D G3DSA:3.40.50.1700 433 661 1.1E-42 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 Gene3D G3DSA:3.20.20.300 66 430 1.2E-106 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 449 660 8.2E-28 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS24470 bdee1fcbc4dcae976e6fea4e5911a924 877 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 334 351 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 SMART SM00344 4 110 1.1E-24 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 Gene3D G3DSA:1.10.10.10 5 57 1.3E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 51 6.7E-11 T 28-03-2018 CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 SUPERFAMILY SSF54909 65 140 2.15E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 1.4E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 1.4E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 1.4E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 SUPERFAMILY SSF46785 4 63 3.57E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 Pfam PF01037 Lrp/AsnC ligand binding domain 71 140 9.0E-19 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS21770 a04cbb8ac8fef6c8f46eb555cbf30bcc 158 Gene3D G3DSA:3.30.70.920 58 136 3.0E-23 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3427 3722 1.5E-112 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 686 984 9.2E-117 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1696 1991 1.0E-110 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.366.10 3417 3590 8.3E-51 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.366.10 3591 3736 9.0E-33 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF53901 2901 3277 1.41E-106 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3068 3084 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF47336 2807 2920 3.53E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF55048 1817 1881 1.24E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.47.10 2903 3167 1.5E-89 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.47.10 1158 1428 7.7E-90 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF53901 1163 1537 3.93E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF55048 3548 3612 7.06E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF51735 2528 2770 1.65E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF47336 1071 1181 3.14E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00698 Acyl transferase domain 1695 2010 2.3E-55 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00698 Acyl transferase domain 685 1002 4.1E-87 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00698 Acyl transferase domain 3427 3741 2.8E-56 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2839 2854 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00826 2057 2218 4.3E-72 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF08659 KR domain 2530 2703 8.2E-48 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.50.720 2523 2764 3.2E-37 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF51735 2339 2518 7.87E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 18 255 2.0E-75 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1166 1416 3.5E-92 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2905 3155 3.5E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00550 Phosphopantetheine attachment site 1079 1144 1.3E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00550 Phosphopantetheine attachment site 3975 4041 1.0E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF00550 Phosphopantetheine attachment site 2814 2880 9.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF53901 15 378 9.66E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1329 1345 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.366.10 869 984 1.4E-25 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.366.10 1873 1997 7.1E-26 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.47.10 20 268 3.5E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2530 2704 5.0E-40 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.10.129.10 2061 2184 1.0E-8 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF14765 Polyketide synthase dehydratase 2057 2334 7.5E-56 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:1.10.1200.10 3956 4052 8.4E-19 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:1.10.1200.10 1037 1156 1.0E-15 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.47.10 271 433 2.7E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00823 Phosphopantetheine attachment site 1076 1148 7.1E-24 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00823 Phosphopantetheine attachment site 2812 2884 1.2E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00823 Phosphopantetheine attachment site 3973 4045 4.7E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF52151 1692 1818 2.2E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF52151 1882 1983 2.2E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF55048 809 874 3.01E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:1.10.1200.10 2805 2902 3.9E-21 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.47.10 3170 3329 4.7E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.47.10 1431 1590 2.9E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.366.10 682 823 9.1E-42 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3163 3278 1.0E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1424 1539 2.4E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 263 378 2.2E-37 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF52151 3423 3549 1.36E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF52151 3613 3706 1.36E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM01294 3975 4041 8.1E-6 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM01294 1077 1144 2.3E-5 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM01294 2813 2880 9.0E-5 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.40.366.10 1689 1826 1.7E-44 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4000 4015 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 381 439 2.4E-10 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1542 1633 4.3E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3281 3389 1.7E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF47336 3967 4055 1.57E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.30.70.250 1827 1872 8.6E-18 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 Gene3D G3DSA:3.30.70.250 824 868 5.0E-17 T 28-03-2018 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF52151 875 971 2.88E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SUPERFAMILY SSF52151 683 811 2.88E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00825 Beta-ketoacyl synthase 2907 3331 1.1E-226 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00825 Beta-ketoacyl synthase 1168 1592 5.7E-227 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS23395 a46aac822d7ecba8c226f15aacdb49e1 4133 SMART SM00825 Beta-ketoacyl synthase 19 431 1.3E-176 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS29020 63993138821399d9495c16d866e3bf59 325 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 27 325 51.397 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CNX65_RS29020 63993138821399d9495c16d866e3bf59 325 SUPERFAMILY SSF47823 28 122 4.51E-11 T 28-03-2018 IPR010998 Integrase, Lambda-type, N-terminal CNX65_RS29020 63993138821399d9495c16d866e3bf59 325 Gene3D G3DSA:1.10.150.130 25 133 3.4E-16 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS29020 63993138821399d9495c16d866e3bf59 325 Gene3D G3DSA:1.10.443.10 135 319 1.5E-43 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS29020 63993138821399d9495c16d866e3bf59 325 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 29 113 4.2E-14 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CNX65_RS29020 63993138821399d9495c16d866e3bf59 325 Pfam PF00589 Phage integrase family 138 310 2.1E-40 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS29020 63993138821399d9495c16d866e3bf59 325 SUPERFAMILY SSF56349 133 323 1.65E-46 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 Gene3D G3DSA:1.20.1250.20 211 397 1.1E-7 T 28-03-2018 CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 Gene3D G3DSA:1.20.1250.20 8 208 3.4E-18 T 28-03-2018 CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 SUPERFAMILY SSF103473 23 393 1.31E-26 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 Pfam PF07690 Major Facilitator Superfamily 25 317 6.2E-11 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 PRINTS PR01035 Tetracycline resistance protein signature 344 366 2.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 PRINTS PR01035 Tetracycline resistance protein signature 226 242 2.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 PRINTS PR01035 Tetracycline resistance protein signature 372 392 2.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS01190 ace7edeb5293b9484d317c3e4e7157b7 420 PRINTS PR01035 Tetracycline resistance protein signature 255 274 2.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS00870 b06d737bc348f993eab4f16ef835b5a1 152 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 46 84 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CNX65_RS00870 b06d737bc348f993eab4f16ef835b5a1 152 SUPERFAMILY SSF53927 5 142 8.32E-42 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS00870 b06d737bc348f993eab4f16ef835b5a1 152 Pfam PF14437 MafB19-like deaminase 15 139 9.1E-21 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CNX65_RS00870 b06d737bc348f993eab4f16ef835b5a1 152 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 2 143 41.435 T 28-03-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 CNX65_RS00870 b06d737bc348f993eab4f16ef835b5a1 152 Gene3D G3DSA:3.40.140.10 1 151 1.8E-40 T 28-03-2018 CNX65_RS17230 08856bdd59d2887eb5ff85f4cac922a9 248 Gene3D G3DSA:1.10.260.40 54 94 2.0E-10 T 28-03-2018 CNX65_RS17230 08856bdd59d2887eb5ff85f4cac922a9 248 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 1.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS17230 08856bdd59d2887eb5ff85f4cac922a9 248 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 87 241 2.2E-15 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CNX65_RS17230 08856bdd59d2887eb5ff85f4cac922a9 248 Gene3D G3DSA:1.10.357.10 95 245 6.7E-36 T 28-03-2018 CNX65_RS17230 08856bdd59d2887eb5ff85f4cac922a9 248 SUPERFAMILY SSF48498 93 244 3.67E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS17230 08856bdd59d2887eb5ff85f4cac922a9 248 SUPERFAMILY SSF46689 22 83 3.03E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS17230 08856bdd59d2887eb5ff85f4cac922a9 248 Gene3D G3DSA:1.10.10.60 15 53 3.8E-14 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 TIGRFAM TIGR00416 sms: DNA repair protein RadA 8 430 6.2E-152 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 SUPERFAMILY SSF54211 301 449 3.0E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 SUPERFAMILY SSF54211 253 267 3.0E-31 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 Gene3D G3DSA:3.40.50.300 72 279 4.9E-39 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 Pfam PF13481 AAA domain 81 220 5.6E-13 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 PRINTS PR01874 DNA repair protein radA signature 246 272 1.5E-82 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 PRINTS PR01874 DNA repair protein radA signature 211 239 1.5E-82 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 PRINTS PR01874 DNA repair protein radA signature 172 196 1.5E-82 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 PRINTS PR01874 DNA repair protein radA signature 320 343 1.5E-82 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 PRINTS PR01874 DNA repair protein radA signature 14 38 1.5E-82 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 PRINTS PR01874 DNA repair protein radA signature 80 108 1.5E-82 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 PRINTS PR01874 DNA repair protein radA signature 122 139 1.5E-82 T 28-03-2018 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 Hamap MF_01498 DNA repair protein RadA [radA]. 25 451 42.607 T 28-03-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 Gene3D G3DSA:3.30.230.10 284 452 3.5E-20 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 SUPERFAMILY SSF52540 72 289 3.32E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 SMART SM00382 88 242 2.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01880 b67ae0309b30102617b94718c003aa5a 462 Pfam PF13541 Subunit ChlI of Mg-chelatase 367 426 5.0E-8 T 28-03-2018 CNX65_RS14620 fc84206fff5681fa6394be300a01395a 644 Gene3D G3DSA:1.10.287.130 248 318 1.2E-10 T 28-03-2018 CNX65_RS14620 fc84206fff5681fa6394be300a01395a 644 SMART SM00304 205 257 3.8E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS14620 fc84206fff5681fa6394be300a01395a 644 SUPERFAMILY SSF47384 242 319 1.29E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS14620 fc84206fff5681fa6394be300a01395a 644 SMART SM00388 258 322 2.1E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS14620 fc84206fff5681fa6394be300a01395a 644 Pfam PF00512 His Kinase A (phospho-acceptor) domain 260 319 4.0E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS14620 fc84206fff5681fa6394be300a01395a 644 SUPERFAMILY SSF55874 325 406 5.19E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS14620 fc84206fff5681fa6394be300a01395a 644 Gene3D G3DSA:3.30.565.10 322 639 8.9E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 13 347 2.1E-109 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 Gene3D G3DSA:3.50.50.60 213 422 3.4E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 14 33 1.6E-9 T 28-03-2018 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 157 175 1.6E-9 T 28-03-2018 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 200 218 1.6E-9 T 28-03-2018 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 Gene3D G3DSA:3.50.50.60 7 212 3.7E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 SUPERFAMILY SSF51905 13 242 2.09E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 SUPERFAMILY SSF51905 276 418 2.09E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 200 225 9.7E-6 T 28-03-2018 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 13 35 9.7E-6 T 28-03-2018 CNX65_RS22340 60bbf38e65eaa2c95dd3347f64eb9b82 422 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 169 9.7E-6 T 28-03-2018 CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 SMART SM00479 22 190 6.6E-48 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 Pfam PF00929 Exonuclease 24 181 2.0E-35 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 18 189 2.4E-31 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 SUPERFAMILY SSF82771 223 303 7.98E-16 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 SUPERFAMILY SSF53098 17 201 1.16E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 Gene3D G3DSA:1.20.5.140 175 193 2.1E-5 T 28-03-2018 CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 Gene3D G3DSA:3.40.1440.10 209 307 2.3E-20 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 SMART SM00465 223 304 3.2E-11 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 Gene3D G3DSA:3.30.420.10 16 174 2.7E-39 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS06820 a180754358b8ad7d98ef221a7fa7501c 570 Pfam PF01541 GIY-YIG catalytic domain 225 299 6.7E-6 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS15355 78f66fe1f75752ae248a72bf4bf2612f 513 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 348 435 1.5E-7 T 28-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CNX65_RS15355 78f66fe1f75752ae248a72bf4bf2612f 513 SUPERFAMILY SSF48239 206 465 1.49E-25 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CNX65_RS15355 78f66fe1f75752ae248a72bf4bf2612f 513 Gene3D G3DSA:1.50.10.20 397 508 7.8E-11 T 28-03-2018 CNX65_RS15355 78f66fe1f75752ae248a72bf4bf2612f 513 Gene3D G3DSA:1.50.10.20 33 396 1.3E-16 T 28-03-2018 CNX65_RS14770 32f05ec74ec77750902945b0b2d80230 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 2.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14770 32f05ec74ec77750902945b0b2d80230 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 2.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14770 32f05ec74ec77750902945b0b2d80230 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 2.8E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14770 32f05ec74ec77750902945b0b2d80230 208 SMART SM00421 145 202 2.9E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14770 32f05ec74ec77750902945b0b2d80230 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 5.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14770 32f05ec74ec77750902945b0b2d80230 208 SUPERFAMILY SSF46894 133 208 1.43E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS14770 32f05ec74ec77750902945b0b2d80230 208 Gene3D G3DSA:1.10.10.10 105 208 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17050 4f1a7211607946cf7bdbc3072c507d02 188 Pfam PF01551 Peptidase family M23 51 166 2.3E-11 T 28-03-2018 IPR016047 Peptidase M23 CNX65_RS17050 4f1a7211607946cf7bdbc3072c507d02 188 SUPERFAMILY SSF51261 45 166 1.1E-16 T 28-03-2018 IPR011055 Duplicated hybrid motif CNX65_RS17050 4f1a7211607946cf7bdbc3072c507d02 188 Gene3D G3DSA:2.70.70.10 28 181 3.9E-19 T 28-03-2018 CNX65_RS08805 d75edf1a73498bb92719c1df933a06b9 93 Pfam PF14019 Protein of unknown function (DUF4235) 7 83 1.1E-25 T 28-03-2018 IPR025329 Protein of unknown function DUF4235 CNX65_RS03385 1b569969c623e7fcc42dad432a7eb330 332 Pfam PF00005 ABC transporter 34 185 2.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03385 1b569969c623e7fcc42dad432a7eb330 332 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 323 4.3E-25 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS03385 1b569969c623e7fcc42dad432a7eb330 332 Gene3D G3DSA:3.40.50.300 2 330 3.7E-82 T 28-03-2018 CNX65_RS03385 1b569969c623e7fcc42dad432a7eb330 332 SMART SM00382 42 235 2.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03385 1b569969c623e7fcc42dad432a7eb330 332 SUPERFAMILY SSF52540 6 257 3.8E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03385 1b569969c623e7fcc42dad432a7eb330 332 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 304 5.0E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS03385 1b569969c623e7fcc42dad432a7eb330 332 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS13655 aad4f1c55f1d8d269632443f6b4c5150 279 Pfam PF00005 ABC transporter 38 184 5.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13655 aad4f1c55f1d8d269632443f6b4c5150 279 SMART SM00382 47 233 3.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13655 aad4f1c55f1d8d269632443f6b4c5150 279 SUPERFAMILY SSF52540 19 237 1.18E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13655 aad4f1c55f1d8d269632443f6b4c5150 279 Gene3D G3DSA:3.40.50.300 14 274 8.3E-65 T 28-03-2018 CNX65_RS13655 aad4f1c55f1d8d269632443f6b4c5150 279 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 TIGRFAM TIGR00211 glyS: glycine--tRNA ligase, beta subunit 306 972 1.4E-160 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 Pfam PF02091 Glycyl-tRNA synthetase alpha subunit 1 277 1.2E-129 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 Gene3D G3DSA:1.20.58.180 204 280 1.1E-26 T 28-03-2018 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 Hamap MF_00254 Glycine--tRNA ligase alpha subunit [glyQ]. 1 279 50.436 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 53 68 3.1E-58 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 131 151 3.1E-58 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 154 169 3.1E-58 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 239 255 3.1E-58 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 105 129 3.1E-58 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 PRINTS PR01044 Glycyl-tRNA synthetase alpha subunit signature 74 94 3.1E-58 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 SUPERFAMILY SSF55681 2 278 8.2E-111 T 28-03-2018 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 Hamap MF_00255 Glycine--tRNA ligase beta subunit [glyS]. 305 980 20.716 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 Pfam PF02092 Glycyl-tRNA synthetase beta subunit 308 852 2.9E-172 T 28-03-2018 IPR015944 Glycine-tRNA ligase, beta subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 TIGRFAM TIGR00388 glyQ: glycine--tRNA ligase, alpha subunit 1 284 1.1E-122 T 28-03-2018 IPR002310 Glycine-tRNA ligase, alpha subunit GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 SUPERFAMILY SSF109604 641 794 5.86E-10 T 28-03-2018 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 Gene3D G3DSA:1.10.730.10 788 977 0.002 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS05210 fe186e438f4b0eef1094374cee1ba52c 982 Gene3D G3DSA:3.30.930.10 1 202 4.3E-72 T 28-03-2018 CNX65_RS24045 0a270fec6c6d1e161366a111c347a357 510 SUPERFAMILY SSF63825 160 273 2.75E-29 T 28-03-2018 CNX65_RS24045 0a270fec6c6d1e161366a111c347a357 510 SUPERFAMILY SSF63825 15 121 2.75E-29 T 28-03-2018 CNX65_RS24045 0a270fec6c6d1e161366a111c347a357 510 Gene3D G3DSA:2.120.10.30 304 510 3.0E-19 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS24045 0a270fec6c6d1e161366a111c347a357 510 SUPERFAMILY SSF63829 316 463 4.58E-22 T 28-03-2018 CNX65_RS24045 0a270fec6c6d1e161366a111c347a357 510 SUPERFAMILY SSF63829 263 282 4.58E-22 T 28-03-2018 CNX65_RS24045 0a270fec6c6d1e161366a111c347a357 510 Gene3D G3DSA:2.120.10.30 2 125 2.0E-13 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS24045 0a270fec6c6d1e161366a111c347a357 510 Gene3D G3DSA:2.120.10.30 126 292 2.3E-15 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 Gene3D G3DSA:1.10.8.60 163 267 7.0E-18 T 28-03-2018 CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 Pfam PF16193 AAA C-terminal domain 196 274 8.8E-25 T 28-03-2018 IPR032423 AAA C-terminal domain CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 Pfam PF12002 MgsA AAA+ ATPase C terminal 275 440 1.5E-67 T 28-03-2018 IPR021886 MgsA AAA+ ATPase C-terminal CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 SUPERFAMILY SSF52540 23 231 1.22E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 Gene3D G3DSA:3.40.50.300 9 162 9.8E-25 T 28-03-2018 CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 Gene3D G3DSA:1.10.3710.10 357 448 1.1E-26 T 28-03-2018 CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 61 165 3.1E-15 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 SUPERFAMILY SSF48019 260 443 1.53E-72 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 Gene3D G3DSA:1.20.272.10 268 353 1.1E-38 T 28-03-2018 CNX65_RS26235 047255a89a7259515439b1ddb039c984 448 SMART SM00382 57 174 2.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03710 873e281474fb709c995485defb8deec8 342 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03710 873e281474fb709c995485defb8deec8 342 Gene3D G3DSA:3.40.50.300 27 300 4.6E-58 T 28-03-2018 CNX65_RS03710 873e281474fb709c995485defb8deec8 342 Pfam PF00005 ABC transporter 44 188 2.3E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03710 873e281474fb709c995485defb8deec8 342 SUPERFAMILY SSF52540 28 251 2.57E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03710 873e281474fb709c995485defb8deec8 342 SMART SM00382 52 245 2.9E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS23685 e995352cf1dee73dd26cce6bf4d414f2 250 SUPERFAMILY SSF52540 4 225 3.18E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23685 e995352cf1dee73dd26cce6bf4d414f2 250 TIGRFAM TIGR03771 anch_rpt_ABC: anchored repeat-type ABC transporter, ATP-binding subunit 27 248 7.2E-97 T 28-03-2018 IPR022508 ABC transporter, anchored repeat-type, ATP-binding subunit CNX65_RS23685 e995352cf1dee73dd26cce6bf4d414f2 250 Pfam PF00005 ABC transporter 21 166 2.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS23685 e995352cf1dee73dd26cce6bf4d414f2 250 SMART SM00382 30 214 1.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS23685 e995352cf1dee73dd26cce6bf4d414f2 250 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS23685 e995352cf1dee73dd26cce6bf4d414f2 250 Gene3D G3DSA:3.40.50.300 1 241 1.4E-59 T 28-03-2018 CNX65_RS12005 b571c292d7b9e826ec5c084fbddd2932 292 SUPERFAMILY SSF64518 5 292 9.29E-52 T 28-03-2018 CNX65_RS12005 b571c292d7b9e826ec5c084fbddd2932 292 Pfam PF00669 Bacterial flagellin N-terminal helical region 10 131 2.9E-14 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CNX65_RS12005 b571c292d7b9e826ec5c084fbddd2932 292 Pfam PF00700 Bacterial flagellin C-terminal helical region 209 291 2.9E-10 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CNX65_RS12005 b571c292d7b9e826ec5c084fbddd2932 292 Gene3D G3DSA:1.20.1330.10 41 266 3.0E-28 T 28-03-2018 CNX65_RS20245 1deb721564b3e1b7e0890714378db097 413 Pfam PF13360 PQQ-like domain 63 314 2.2E-10 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CNX65_RS20245 1deb721564b3e1b7e0890714378db097 413 SUPERFAMILY SSF50998 58 330 1.57E-9 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS20245 1deb721564b3e1b7e0890714378db097 413 Gene3D G3DSA:2.140.10.10 27 189 1.1E-5 T 28-03-2018 CNX65_RS20245 1deb721564b3e1b7e0890714378db097 413 Gene3D G3DSA:2.140.10.10 196 410 6.2E-9 T 28-03-2018 CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 SUPERFAMILY SSF88946 178 260 2.86E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 Pfam PF04542 Sigma-70 region 2 192 252 1.2E-5 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 Gene3D G3DSA:1.10.10.10 263 344 8.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 Pfam PF08281 Sigma-70, region 4 287 335 4.4E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 200 335 2.3E-15 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 Gene3D G3DSA:1.10.1740.10 165 262 1.1E-11 T 28-03-2018 CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 Pfam PF09594 Glycosyltransferase family 87 5 155 3.2E-21 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CNX65_RS13205 0606b8c77e07f67ce545fe4796634e2d 506 SUPERFAMILY SSF88659 281 335 5.01E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS00795 340939b05fad141d2813c6e4fecc647f 464 Pfam PF17210 SdrD B-like domain 273 340 3.6E-14 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS00795 340939b05fad141d2813c6e4fecc647f 464 SUPERFAMILY SSF117074 275 344 5.49E-11 T 28-03-2018 CNX65_RS00795 340939b05fad141d2813c6e4fecc647f 464 Gene3D G3DSA:2.60.40.10 267 422 4.0E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS04330 12355acd9adbe990b768d9b16c6b2e2f 347 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 203 216 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CNX65_RS04330 12355acd9adbe990b768d9b16c6b2e2f 347 Pfam PF00155 Aminotransferase class I and II 33 340 5.4E-26 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS04330 12355acd9adbe990b768d9b16c6b2e2f 347 SUPERFAMILY SSF53383 20 341 3.69E-58 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS04330 12355acd9adbe990b768d9b16c6b2e2f 347 Gene3D G3DSA:3.40.640.10 48 236 1.7E-24 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS04330 12355acd9adbe990b768d9b16c6b2e2f 347 Gene3D G3DSA:3.90.1150.10 237 339 9.1E-17 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS00425 5c23eab02864996a444e336db869ccbb 217 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 4 202 6.7E-55 T 28-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 CNX65_RS00425 5c23eab02864996a444e336db869ccbb 217 Gene3D G3DSA:1.10.3630.10 1 214 5.7E-46 T 28-03-2018 CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 SUPERFAMILY SSF46894 425 490 2.21E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 433 447 2.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 447 463 2.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 463 475 2.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 SMART SM00421 430 487 8.7E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 Gene3D G3DSA:1.10.10.10 414 491 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 Pfam PF00196 Bacterial regulatory proteins, luxR family 433 480 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS19540 99302896df6c1857c0ff9bb0496bea0a 503 Gene3D G3DSA:1.10.260.40 291 343 0.35 T 28-03-2018 CNX65_RS24310 e7cf039c9c4e983b9b364be9457bc224 486 Pfam PF00939 Sodium:sulfate symporter transmembrane region 33 478 4.6E-28 T 28-03-2018 IPR001898 Solute carrier family 13 GO:0005215|GO:0006814|GO:0016020|GO:0055085 Reactome: R-HSA-433137 CNX65_RS23100 f1a862f6228f0c32450f65d808b0be09 263 Gene3D G3DSA:3.30.450.20 84 258 0.038 T 28-03-2018 CNX65_RS23100 f1a862f6228f0c32450f65d808b0be09 263 SMART SM00530 4 59 2.7E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS23100 f1a862f6228f0c32450f65d808b0be09 263 Gene3D G3DSA:1.10.260.40 1 76 4.7E-14 T 28-03-2018 CNX65_RS23100 f1a862f6228f0c32450f65d808b0be09 263 Pfam PF13560 Helix-turn-helix domain 2 62 1.3E-14 T 28-03-2018 CNX65_RS23100 f1a862f6228f0c32450f65d808b0be09 263 SUPERFAMILY SSF47413 2 56 1.53E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 5 274 2.9E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 1012 1280 2.8E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 3466 3735 2.0E-89 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 2489 2753 2.4E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF53901 2488 2863 1.67E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF53901 3471 3846 4.01E-106 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF51735 4340 4543 1.1E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1181 1197 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF47336 4821 4904 1.44E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:1.10.1200.10 2395 2488 1.5E-19 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00823 Phosphopantetheine attachment site 2398 2470 3.9E-30 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00823 Phosphopantetheine attachment site 4827 4898 3.5E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00823 Phosphopantetheine attachment site 3384 3456 5.2E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00823 Phosphopantetheine attachment site 928 1000 4.9E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF51735 2119 2345 1.2E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF55048 659 720 2.35E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 721 822 1.05E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 540 660 1.05E-71 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF08659 KR domain 2123 2296 1.4E-54 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF08659 KR domain 4553 4727 2.3E-54 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF51735 1933 2110 5.51E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 1535 1661 3.92E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 1725 1824 3.92E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 ProSitePatterns PS00012 Phosphopantetheine attachment site. 4853 4868 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2123 2298 2.0E-52 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4553 4729 2.1E-52 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3636 3652 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 3198 3291 1.67E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 3011 3137 1.67E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:1.10.1200.10 3362 3462 3.1E-19 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:1.10.1200.10 4811 4901 1.5E-19 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.30.70.250 1671 1717 1.3E-16 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.30.70.250 670 710 2.5E-17 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.30.70.250 3147 3189 5.5E-16 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF51735 4549 4792 1.08E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 2756 2915 2.6E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 3738 3897 2.1E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 1283 1442 6.6E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF47336 2396 2506 3.93E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 1718 1835 1.5E-28 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 3190 3308 1.4E-22 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 4182 4272 4.19E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF52151 4002 4121 4.19E-63 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00825 Beta-ketoacyl synthase 2493 2917 1.1E-223 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00825 Beta-ketoacyl synthase 1020 1444 6.2E-223 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00825 Beta-ketoacyl synthase 3475 3899 2.4E-228 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00825 Beta-ketoacyl synthase 15 440 1.2E-197 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 3011 3146 9.4E-38 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 4000 4127 2.5E-38 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 539 669 6.9E-41 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2425 2440 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.47.10 278 442 1.6E-54 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF55048 4120 4181 2.62E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3473 3723 1.7E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2491 2741 1.5E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 13 262 8.6E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1018 1268 3.9E-92 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.50.720 4545 4793 3.6E-53 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.50.720 2115 2369 2.1E-52 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:1.10.1200.10 909 1008 2.4E-19 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 ProSitePatterns PS00012 Phosphopantetheine attachment site. 955 970 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2654 2670 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.30.70.250 4128 4169 2.9E-16 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF55048 1659 1724 3.4E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM01294 2399 2466 0.0011 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM01294 4828 4894 6.5E-6 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM01294 929 996 0.0016 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM01294 3385 3452 3.0E-4 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2749 2864 7.8E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 270 388 6.3E-37 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1276 1391 6.1E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3731 3846 1.0E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF47336 3382 3488 3.4E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 1532 1670 1.6E-42 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF47336 925 1033 1.31E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3849 3966 8.8E-15 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 390 506 1.6E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1394 1483 2.0E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2867 2974 9.2E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00550 Phosphopantetheine attachment site 4833 4894 9.5E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00550 Phosphopantetheine attachment site 929 996 5.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00550 Phosphopantetheine attachment site 2404 2466 1.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00550 Phosphopantetheine attachment site 3386 3452 1.7E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF53901 11 383 2.54E-88 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 711 831 6.3E-31 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Gene3D G3DSA:3.40.366.10 4170 4279 2.4E-29 T 28-03-2018 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1539 1833 3.6E-124 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 3015 3302 3.0E-109 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 543 827 2.8E-114 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4004 4297 4.3E-98 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF53901 1017 1388 3.42E-105 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00698 Acyl transferase domain 3014 3321 2.1E-80 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00698 Acyl transferase domain 542 845 6.6E-55 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00698 Acyl transferase domain 4003 4266 3.5E-49 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 Pfam PF00698 Acyl transferase domain 1537 1852 3.1E-96 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3411 3426 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15325 986378c4d9e74707a590999a2cace526 4972 SUPERFAMILY SSF55048 3135 3197 1.44E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 Gene3D G3DSA:2.60.40.420 39 142 4.6E-7 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 Gene3D G3DSA:2.60.40.420 165 315 6.5E-31 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 SUPERFAMILY SSF49503 314 455 1.27E-36 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 SUPERFAMILY SSF49503 194 330 2.11E-35 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 Gene3D G3DSA:2.60.40.420 316 455 4.0E-15 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 Pfam PF07732 Multicopper oxidase 205 314 6.1E-15 T 28-03-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 PRINTS PR00695 Copper containing nitrite reductase signature 222 238 4.7E-10 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 PRINTS PR00695 Copper containing nitrite reductase signature 296 312 4.7E-10 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 PRINTS PR00695 Copper containing nitrite reductase signature 279 294 4.7E-10 T 28-03-2018 IPR001287 Nitrite reductase, copper-type GO:0005507|GO:0006807|GO:0050421|GO:0055114 KEGG: 00910+1.7.2.1|MetaCyc: PWY-6523|MetaCyc: PWY-6748|MetaCyc: PWY-7084 CNX65_RS23620 65c5c7400922d41889474cb77b716dc0 455 SUPERFAMILY SSF49503 60 141 4.82E-10 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 ProSitePatterns PS00163 Fumarate lyases signature. 279 288 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 SUPERFAMILY SSF48557 9 454 8.33E-81 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 Gene3D G3DSA:1.20.200.10 102 381 1.7E-57 T 28-03-2018 CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 Pfam PF00206 Lyase 35 303 3.4E-21 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 Pfam PF10397 Adenylosuccinate lyase C-terminus 369 453 1.0E-12 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 SMART SM00998 368 454 2.3E-19 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 PRINTS PR00149 Fumarate lyase superfamily signature 97 115 9.9E-11 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 PRINTS PR00149 Fumarate lyase superfamily signature 236 263 9.9E-11 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 PRINTS PR00149 Fumarate lyase superfamily signature 279 295 9.9E-11 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 PRINTS PR00149 Fumarate lyase superfamily signature 142 160 9.9E-11 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 Gene3D G3DSA:1.10.275.10 7 101 9.4E-16 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 10 453 1.2E-126 T 28-03-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS34045 c4e68b6ecf3a777e702c31215cddd5b7 476 Gene3D G3DSA:1.10.40.30 382 453 9.3E-17 T 28-03-2018 CNX65_RS03650 4d1a0620eaedc57d7e58b71730930892 970 Pfam PF13558 Putative exonuclease SbcCD, C subunit 869 928 2.2E-11 T 28-03-2018 CNX65_RS03650 4d1a0620eaedc57d7e58b71730930892 970 Gene3D G3DSA:3.40.50.300 2 970 3.8E-40 T 28-03-2018 CNX65_RS03650 4d1a0620eaedc57d7e58b71730930892 970 SUPERFAMILY SSF52540 569 621 2.16E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03650 4d1a0620eaedc57d7e58b71730930892 970 SUPERFAMILY SSF52540 819 958 2.16E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03650 4d1a0620eaedc57d7e58b71730930892 970 SUPERFAMILY SSF52540 2 221 2.16E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03650 4d1a0620eaedc57d7e58b71730930892 970 Pfam PF13476 AAA domain 5 207 1.6E-24 T 28-03-2018 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Hamap MF_00347 Polyphosphate kinase [ppk]. 33 710 29.477 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 SUPERFAMILY SSF56024 532 706 3.36E-62 T 28-03-2018 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Gene3D G3DSA:3.30.870.10 531 711 3.1E-40 T 28-03-2018 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Pfam PF13090 Polyphosphate kinase C-terminal domain 360 704 7.8E-149 T 28-03-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 SUPERFAMILY SSF140356 32 136 4.45E-37 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Pfam PF02503 Polyphosphate kinase middle domain 153 349 1.2E-68 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Gene3D G3DSA:1.20.58.310 37 139 3.1E-36 T 28-03-2018 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 34 705 5.0E-250 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Pfam PF13089 Polyphosphate kinase N-terminal domain 35 141 8.9E-37 T 28-03-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 SUPERFAMILY SSF56024 351 526 3.08E-56 T 28-03-2018 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Gene3D G3DSA:3.30.870.10 344 530 5.9E-20 T 28-03-2018 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 Gene3D G3DSA:3.30.1840.10 140 334 7.9E-73 T 28-03-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 SUPERFAMILY SSF143724 138 339 6.67E-66 T 28-03-2018 CNX65_RS29510 bdbc02b08f458d98eb4bda924099cb17 712 PIRSF PIRSF015589 17 711 9.8E-272 T 28-03-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 SUPERFAMILY SSF47336 479 552 2.75E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Gene3D G3DSA:2.30.38.10 291 367 2.8E-23 T 28-03-2018 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 25 401 2.0E-115 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Gene3D G3DSA:3.30.300.30 372 494 1.6E-38 T 28-03-2018 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 SMART SM00823 Phosphopantetheine attachment site 487 556 1.3E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Gene3D G3DSA:1.10.1200.10 495 559 1.1E-22 T 28-03-2018 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Gene3D G3DSA:3.40.50.980 107 290 9.0E-46 T 28-03-2018 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Pfam PF00501 AMP-binding enzyme 8 97 6.9E-17 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Pfam PF00501 AMP-binding enzyme 113 377 1.7E-65 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Pfam PF00550 Phosphopantetheine attachment site 488 552 1.0E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 ProSitePatterns PS00455 Putative AMP-binding domain signature. 124 135 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 SUPERFAMILY SSF56801 2 499 1.44E-138 T 28-03-2018 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Gene3D G3DSA:3.40.50.980 1 106 1.0E-22 T 28-03-2018 CNX65_RS22375 d9339ef53c688471d05b62ee6b5e048b 559 Pfam PF13193 AMP-binding enzyme C-terminal domain 385 458 1.7E-13 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS32130 b564f8071810d2686b75b11d5ab6430b 232 Gene3D G3DSA:3.30.420.40 1 146 5.4E-34 T 28-03-2018 CNX65_RS32130 b564f8071810d2686b75b11d5ab6430b 232 SUPERFAMILY SSF53067 3 107 7.77E-21 T 28-03-2018 CNX65_RS32130 b564f8071810d2686b75b11d5ab6430b 232 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 216 2.3E-51 T 28-03-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 CNX65_RS32130 b564f8071810d2686b75b11d5ab6430b 232 SUPERFAMILY SSF53067 118 214 7.9E-11 T 28-03-2018 CNX65_RS32130 b564f8071810d2686b75b11d5ab6430b 232 Pfam PF00814 Glycoprotease family 37 155 4.7E-26 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS18980 56b88560b4fa79948217ed478200a18a 136 SUPERFAMILY SSF50346 8 133 7.85E-15 T 28-03-2018 IPR011033 PRC-barrel-like CNX65_RS18980 56b88560b4fa79948217ed478200a18a 136 Gene3D G3DSA:3.90.50.10 13 135 1.1E-8 T 28-03-2018 CNX65_RS05280 0c438cb818867f07d5a4481c651547a5 371 ProDom PD120223 SCO3432 GENE ML2604 GP79 GP77 CGL2230 MB0190 164 346 2.0E-27 T 28-03-2018 CNX65_RS05280 0c438cb818867f07d5a4481c651547a5 371 Pfam PF10979 Protein of unknown function (DUF2786) 162 200 3.2E-14 T 28-03-2018 IPR024498 Domain of unknown function DUF2786 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 Pfam PF00330 Aconitase family (aconitate hydratase) 68 601 5.6E-179 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 Pfam PF00694 Aconitase C-terminal domain 731 860 7.8E-43 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 367 381 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 169 177 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 198 211 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 212 227 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 532 545 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 145 158 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 288 301 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 274 287 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 PRINTS PR00415 Aconitase family signature 470 481 1.5E-42 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 Gene3D G3DSA:3.40.1060.10 235 366 1.0E-43 T 28-03-2018 IPR015932 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 2 GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 SUPERFAMILY SSF53732 440 666 4.58E-222 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 SUPERFAMILY SSF53732 8 401 4.58E-222 T 28-03-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 ProSitePatterns PS00450 Aconitase family signature 1. 466 482 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 Gene3D G3DSA:3.30.499.10 23 234 1.4E-72 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 ProSitePatterns PS01244 Aconitase family signature 2. 532 545 - T 28-03-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 SUPERFAMILY SSF52016 670 934 8.63E-83 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 Gene3D G3DSA:3.20.19.10 692 936 3.3E-91 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CNX65_RS10875 a83308cf9123a163f7ad13bb934d082e 937 Gene3D G3DSA:3.30.499.10 367 615 1.0E-66 T 28-03-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 Pfam PF00117 Glutamine amidotransferase class-I 4 185 1.7E-35 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 Gene3D G3DSA:3.40.50.880 1 191 7.4E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 Gene3D G3DSA:3.60.120.10 212 669 9.1E-151 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 46 60 1.5E-6 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 77 93 1.5E-6 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 Pfam PF00425 chorismate binding enzyme 403 657 2.9E-87 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 SUPERFAMILY SSF56322 212 666 1.44E-125 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 4 185 1.4E-37 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 316 659 4.8E-111 T 28-03-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 SUPERFAMILY SSF52317 1 188 2.9E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 Pfam PF04715 Anthranilate synthase component I, N terminal region 222 361 4.3E-19 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00097 Anthranilate synthase component II signature 121 133 1.1E-25 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00097 Anthranilate synthase component II signature 77 88 1.1E-25 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00097 Anthranilate synthase component II signature 49 58 1.1E-25 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.1E-25 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00097 Anthranilate synthase component II signature 165 178 1.1E-25 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00096 Glutamine amidotransferase superfamily signature 77 88 1.4E-12 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00096 Glutamine amidotransferase superfamily signature 49 58 1.4E-12 T 28-03-2018 CNX65_RS27675 842728e2bdc9bfb14422c24df62030fb 672 PRINTS PR00096 Glutamine amidotransferase superfamily signature 165 178 1.4E-12 T 28-03-2018 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 SMART SM00919 167 387 1.4E-99 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 PIRSF PIRSF000106 8 392 1.3E-67 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 Pfam PF00390 Malic enzyme, N-terminal domain 35 154 3.1E-22 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 Gene3D G3DSA:3.40.50.720 165 392 4.1E-64 T 28-03-2018 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 SMART SM01274 22 155 5.2E-69 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 SUPERFAMILY SSF53223 15 165 5.61E-49 T 28-03-2018 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 SUPERFAMILY SSF51735 167 392 1.97E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 Pfam PF03949 Malic enzyme, NAD binding domain 169 382 2.1E-18 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CNX65_RS30920 f15486256e335e2f96f39e645f13d5cf 392 Gene3D G3DSA:3.40.50.10380 14 164 1.1E-30 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CNX65_RS21920 12cdd1d86ad54926f5c7b7900c627728 1055 Gene3D G3DSA:3.40.50.300 304 444 5.5E-13 T 28-03-2018 CNX65_RS21920 12cdd1d86ad54926f5c7b7900c627728 1055 Gene3D G3DSA:3.40.50.300 76 282 2.3E-28 T 28-03-2018 CNX65_RS21920 12cdd1d86ad54926f5c7b7900c627728 1055 SMART SM00487 103 307 1.2E-18 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS21920 12cdd1d86ad54926f5c7b7900c627728 1055 SUPERFAMILY SSF52540 128 443 1.02E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21920 12cdd1d86ad54926f5c7b7900c627728 1055 Pfam PF00271 Helicase conserved C-terminal domain 362 433 4.2E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS21920 12cdd1d86ad54926f5c7b7900c627728 1055 SMART SM00490 351 433 5.8E-7 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS21920 12cdd1d86ad54926f5c7b7900c627728 1055 Pfam PF04851 Type III restriction enzyme, res subunit 107 275 2.0E-20 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 Gene3D G3DSA:1.10.3110.10 123 206 6.7E-22 T 28-03-2018 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 Pfam PF01593 Flavin containing amine oxidoreductase 13 464 5.0E-47 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 SUPERFAMILY SSF51905 5 321 3.11E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 SUPERFAMILY SSF51905 433 465 3.11E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 4 466 6.4E-57 T 28-03-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 Gene3D G3DSA:3.90.660.20 44 122 3.8E-6 T 28-03-2018 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 Gene3D G3DSA:3.90.660.20 228 416 9.6E-37 T 28-03-2018 CNX65_RS07705 9d467894ecb36fcc0b2869881dca034c 473 SUPERFAMILY SSF54373 306 416 3.92E-21 T 28-03-2018 CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 Pfam PF02540 NAD synthase 297 544 2.1E-68 T 28-03-2018 IPR022310 NAD/GMP synthase CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 PIRSF PIRSF006630 1 571 6.2E-203 T 28-03-2018 IPR014445 Glutamine-dependent NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.5.1|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 SUPERFAMILY SSF56317 1 249 8.37E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 Gene3D G3DSA:3.60.110.10 1 263 2.4E-62 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 ProSitePatterns PS00920 Nitrilases / cyanide hydratase signature 1. 36 51 - T 28-03-2018 IPR000132 Nitrilase/cyanide hydratase, conserved site GO:0016810 CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 Gene3D G3DSA:3.40.50.620 294 571 1.6E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 SUPERFAMILY SSF52402 285 553 4.93E-73 T 28-03-2018 CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 TIGRFAM TIGR00552 nadE: NAD+ synthetase 300 550 5.9E-57 T 28-03-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 CNX65_RS04450 b9863b7ec6faeaa41167d8622c8327c8 571 Pfam PF00795 Carbon-nitrogen hydrolase 5 250 2.5E-31 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS18275 5a7568cf27757f83d8355aabd986611e 471 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 269 280 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS18275 5a7568cf27757f83d8355aabd986611e 471 Gene3D G3DSA:3.40.309.10 260 450 1.6E-57 T 28-03-2018 CNX65_RS18275 5a7568cf27757f83d8355aabd986611e 471 Pfam PF00171 Aldehyde dehydrogenase family 17 464 8.8E-125 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS18275 5a7568cf27757f83d8355aabd986611e 471 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 241 248 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS18275 5a7568cf27757f83d8355aabd986611e 471 Gene3D G3DSA:3.40.605.10 11 259 1.0E-69 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS18275 5a7568cf27757f83d8355aabd986611e 471 SUPERFAMILY SSF53720 15 467 4.58E-127 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS13670 00541b52a59f8a4713a711be6dc356ed 429 Gene3D G3DSA:3.30.565.10 205 420 2.8E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13670 00541b52a59f8a4713a711be6dc356ed 429 Pfam PF13796 Putative sensor 22 202 4.0E-18 T 28-03-2018 IPR025828 Putative sensor domain CNX65_RS13670 00541b52a59f8a4713a711be6dc356ed 429 SMART SM00387 331 421 0.0016 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13670 00541b52a59f8a4713a711be6dc356ed 429 Pfam PF07730 Histidine kinase 231 298 1.2E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS13670 00541b52a59f8a4713a711be6dc356ed 429 SUPERFAMILY SSF55874 313 419 2.62E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 SUPERFAMILY SSF48008 84 220 3.14E-18 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 Pfam PF07729 FCD domain 85 212 3.5E-24 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 1.2E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 Gene3D G3DSA:1.10.10.10 1 70 1.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 SUPERFAMILY SSF46785 10 79 5.24E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 SMART SM00345 17 75 2.2E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 SMART SM00895 85 214 2.1E-15 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS22040 d47ab5363ffaaa9724b9ae8c82d05f16 223 Gene3D G3DSA:1.20.120.530 71 222 3.1E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS16520 c688f65e1ee96673a302624de1c7fccb 375 SUPERFAMILY SSF55347 128 328 2.13E-19 T 28-03-2018 CNX65_RS16520 c688f65e1ee96673a302624de1c7fccb 375 Gene3D G3DSA:3.30.360.10 130 364 8.9E-23 T 28-03-2018 CNX65_RS16520 c688f65e1ee96673a302624de1c7fccb 375 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 137 187 4.2E-4 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS16520 c688f65e1ee96673a302624de1c7fccb 375 Gene3D G3DSA:3.40.50.720 1 129 2.3E-22 T 28-03-2018 CNX65_RS16520 c688f65e1ee96673a302624de1c7fccb 375 SUPERFAMILY SSF51735 1 150 9.33E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16520 c688f65e1ee96673a302624de1c7fccb 375 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 115 3.5E-17 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS32500 fc44dcd3b7eedbd8a3baa68262530ac1 551 SUPERFAMILY SSF160424 143 277 1.37E-8 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS32500 fc44dcd3b7eedbd8a3baa68262530ac1 551 SUPERFAMILY SSF82171 327 396 3.88E-6 T 28-03-2018 CNX65_RS32500 fc44dcd3b7eedbd8a3baa68262530ac1 551 SUPERFAMILY SSF82171 215 283 3.88E-6 T 28-03-2018 CNX65_RS32500 fc44dcd3b7eedbd8a3baa68262530ac1 551 SUPERFAMILY SSF82171 24 130 3.88E-6 T 28-03-2018 CNX65_RS32500 fc44dcd3b7eedbd8a3baa68262530ac1 551 Gene3D G3DSA:2.130.10.10 3 512 0.0081 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 Gene3D G3DSA:2.160.10.10 14 94 7.9E-7 T 28-03-2018 CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 Gene3D G3DSA:1.20.140.10 306 455 9.2E-14 T 28-03-2018 CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 SUPERFAMILY SSF47203 306 454 1.43E-16 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 Gene3D G3DSA:2.40.110.10 222 305 3.5E-10 T 28-03-2018 CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 Gene3D G3DSA:2.160.10.10 95 221 4.8E-19 T 28-03-2018 CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 306 444 8.7E-14 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 52 86 5.2E-6 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 SUPERFAMILY SSF51161 51 190 1.33E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS16670 9814313054b53c96431a1d939fc0e949 458 SUPERFAMILY SSF56645 219 307 1.41E-11 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS04780 72350ea773e2a6ffab60ad63a34680d4 118 SUPERFAMILY SSF55620 1 117 1.39E-41 T 28-03-2018 CNX65_RS04780 72350ea773e2a6ffab60ad63a34680d4 118 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 3 93 3.7E-32 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CNX65_RS04780 72350ea773e2a6ffab60ad63a34680d4 118 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 3 117 2.5E-35 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CNX65_RS04780 72350ea773e2a6ffab60ad63a34680d4 118 PIRSF PIRSF006113 1 118 6.0E-44 T 28-03-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family protein Reactome: R-HSA-1474151 CNX65_RS04780 72350ea773e2a6ffab60ad63a34680d4 118 Gene3D G3DSA:3.30.479.10 1 118 1.2E-40 T 28-03-2018 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 Gene3D G3DSA:3.30.70.580 34 140 7.4E-34 T 28-03-2018 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 Pfam PF01416 tRNA pseudouridine synthase 183 280 2.4E-19 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 Pfam PF01416 tRNA pseudouridine synthase 44 138 3.4E-6 T 28-03-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 37 279 30.389 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 Gene3D G3DSA:3.30.70.660 141 278 3.3E-28 T 28-03-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 39 273 4.9E-51 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 PIRSF PIRSF001430 36 296 4.1E-69 T 28-03-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS32290 5a65ef2f83fbe4efa235cdee37cfac68 301 SUPERFAMILY SSF55120 36 284 3.74E-72 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS05155 4d35c5abe697bb9f80233d35696fa717 322 Gene3D G3DSA:3.40.50.300 1 184 1.1E-33 T 28-03-2018 CNX65_RS05155 4d35c5abe697bb9f80233d35696fa717 322 Gene3D G3DSA:3.30.1220.10 194 303 1.6E-21 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS05155 4d35c5abe697bb9f80233d35696fa717 322 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 5 160 7.0E-35 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CNX65_RS05155 4d35c5abe697bb9f80233d35696fa717 322 SMART SM00833 213 302 5.0E-22 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS05155 4d35c5abe697bb9f80233d35696fa717 322 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 214 301 1.4E-21 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS05155 4d35c5abe697bb9f80233d35696fa717 322 SUPERFAMILY SSF90002 214 301 4.97E-16 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS05155 4d35c5abe697bb9f80233d35696fa717 322 SUPERFAMILY SSF52540 2 192 4.04E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 SUPERFAMILY SSF52540 354 525 1.26E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 Gene3D G3DSA:3.40.50.300 2 296 2.7E-44 T 28-03-2018 CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 SMART SM00382 28 230 2.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 SMART SM00382 371 536 5.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 Pfam PF00005 ABC transporter 364 490 4.0E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 Pfam PF00005 ABC transporter 19 185 3.5E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 Gene3D G3DSA:3.40.50.300 310 534 9.9E-35 T 28-03-2018 CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 SUPERFAMILY SSF52540 4 238 4.13E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02510 35e89a713fb87e6846d2d0dd1ef730b7 537 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 Gene3D G3DSA:3.40.50.300 1004 1188 7.7E-16 T 28-03-2018 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 Gene3D G3DSA:1.20.1170.10 382 764 8.9E-5 T 28-03-2018 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1187 22.156 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 SMART SM00968 510 622 3.2E-18 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 SUPERFAMILY SSF52540 2 207 7.57E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 SUPERFAMILY SSF52540 994 1179 7.57E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 Gene3D G3DSA:3.40.50.300 2 230 9.6E-41 T 28-03-2018 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1185 1.8E-285 T 28-03-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 Pfam PF06470 SMC proteins Flexible Hinge Domain 510 621 1.9E-17 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 PIRSF PIRSF005719 1 1191 3.6E-249 T 28-03-2018 IPR024704 Structural maintenance of chromosomes protein CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 SUPERFAMILY SSF75553 465 666 1.83E-24 T 28-03-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 CNX65_RS29225 09b16f9f3e8dd9c522e8645fbcab9752 1191 Pfam PF02463 RecF/RecN/SMC N terminal domain 3 1178 1.6E-70 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CNX65_RS28280 c2eedd20fb7075b70f725fed209dd1a8 635 SUPERFAMILY SSF56601 275 621 4.61E-88 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS28280 c2eedd20fb7075b70f725fed209dd1a8 635 Gene3D G3DSA:3.40.710.10 272 621 5.3E-85 T 28-03-2018 CNX65_RS28280 c2eedd20fb7075b70f725fed209dd1a8 635 Pfam PF03717 Penicillin-binding Protein dimerisation domain 77 247 5.8E-13 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CNX65_RS28280 c2eedd20fb7075b70f725fed209dd1a8 635 Pfam PF00905 Penicillin binding protein transpeptidase domain 301 611 2.8E-81 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CNX65_RS28280 c2eedd20fb7075b70f725fed209dd1a8 635 Gene3D G3DSA:3.90.1310.10 46 271 3.2E-34 T 28-03-2018 CNX65_RS28280 c2eedd20fb7075b70f725fed209dd1a8 635 SUPERFAMILY SSF56519 76 273 6.93E-26 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CNX65_RS12285 8140eb0efb1396bb482aff9024c723b9 752 SUPERFAMILY SSF51998 12 750 4.58E-270 T 28-03-2018 CNX65_RS12285 8140eb0efb1396bb482aff9024c723b9 752 Pfam PF02901 Pyruvate formate lyase-like 26 611 1.5E-193 T 28-03-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 CNX65_RS12285 8140eb0efb1396bb482aff9024c723b9 752 PIRSF PIRSF000379 12 752 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CNX65_RS12285 8140eb0efb1396bb482aff9024c723b9 752 ProSitePatterns PS00850 Glycine radical domain signature. 722 730 - T 28-03-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site CNX65_RS12285 8140eb0efb1396bb482aff9024c723b9 752 Pfam PF01228 Glycine radical 627 733 1.6E-39 T 28-03-2018 IPR001150 Glycine radical domain GO:0003824|GO:0008152 CNX65_RS12285 8140eb0efb1396bb482aff9024c723b9 752 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 14 750 0.0 T 28-03-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 CNX65_RS12285 8140eb0efb1396bb482aff9024c723b9 752 Gene3D G3DSA:3.20.70.20 8 752 1.9E-281 T 28-03-2018 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 Hamap MF_00318 Enolase [eno]. 2 409 45.396 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 Gene3D G3DSA:3.30.390.10 3 127 2.9E-50 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 SUPERFAMILY SSF54826 4 136 5.74E-51 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 ProSitePatterns PS00164 Enolase signature. 332 345 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 Pfam PF03952 Enolase, N-terminal domain 4 134 9.2E-56 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 SUPERFAMILY SSF51604 138 422 7.35E-127 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 SMART SM01192 139 423 4.4E-217 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 6.7E-204 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 SMART SM01193 4 134 9.5E-85 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 419 7.0E-128 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 PRINTS PR00148 Enolase signature 332 346 4.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 PRINTS PR00148 Enolase signature 361 378 4.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 PRINTS PR00148 Enolase signature 161 174 4.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 PRINTS PR00148 Enolase signature 309 320 4.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 PRINTS PR00148 Enolase signature 37 51 4.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 PRINTS PR00148 Enolase signature 107 123 4.2E-49 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 Gene3D G3DSA:3.20.20.120 128 427 6.3E-101 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS03330 559a5e4ad5c1b5e274febd65f034308d 428 PIRSF PIRSF001400 1 422 2.6E-190 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 Gene3D G3DSA:1.10.10.10 1 94 9.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 SUPERFAMILY SSF46785 3 88 3.43E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 Gene3D G3DSA:1.10.10.10 111 203 0.044 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 SMART SM00418 8 87 5.0E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 1.7E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 1.7E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 1.7E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS30530 05a4ea6879ed1645983e2bca1799090b 255 Pfam PF12840 Helix-turn-helix domain 9 67 3.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05455 88d0461c3a1e5dbc50bfb0774a2242a1 199 SUPERFAMILY SSF159234 27 185 2.09E-16 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS05455 88d0461c3a1e5dbc50bfb0774a2242a1 199 Pfam PF04167 Protein of unknown function (DUF402) 71 135 1.3E-10 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS05455 88d0461c3a1e5dbc50bfb0774a2242a1 199 Gene3D G3DSA:2.40.380.10 2 183 2.3E-33 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 SUPERFAMILY SSF46894 151 222 3.1E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 Gene3D G3DSA:1.10.10.10 139 225 7.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 SUPERFAMILY SSF52172 15 142 3.98E-16 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 Pfam PF00072 Response regulator receiver domain 18 127 3.1E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 SMART SM00448 15 127 1.2E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 SMART SM00421 153 210 0.0018 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 Gene3D G3DSA:3.40.50.2300 15 138 7.6E-15 T 28-03-2018 CNX65_RS09390 715ce028b398df2b57c0d20c7ddd9f47 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 197 7.6E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 SUPERFAMILY SSF51338 3 181 1.98E-56 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 Pfam PF00449 Urease alpha-subunit, N-terminal domain 3 124 6.9E-51 T 28-03-2018 IPR011612 Urease alpha-subunit, N-terminal domain KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 Gene3D G3DSA:3.20.20.140 421 551 1.1E-43 T 28-03-2018 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 Gene3D G3DSA:3.20.20.140 149 420 1.9E-149 T 28-03-2018 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 SUPERFAMILY SSF51556 479 565 1.62E-181 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 SUPERFAMILY SSF51556 135 432 1.62E-181 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 ProSitePatterns PS01120 Urease nickel ligands signature. 133 146 - T 28-03-2018 IPR029754 Urease nickel binding site GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 Hamap MF_01953 Urease subunit alpha [ureC]. 2 565 54.193 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 TIGRFAM TIGR01792 urease_alph: urease, alpha subunit 4 565 3.1E-261 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 ProSitePatterns PS00145 Urease active site. 323 339 - T 28-03-2018 IPR017950 Urease active site GO:0009039 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 Gene3D G3DSA:2.30.40.10 68 148 4.4E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 401 416 3.8E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 427 440 3.8E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 340 356 3.8E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 PRINTS PR01752 Urea amidohydrolase (urease) protein signature 301 318 3.8E-33 T 28-03-2018 IPR005848 Urease, alpha subunit GO:0006807|GO:0009039|GO:0016151 KEGG: 00220+3.5.1.5|KEGG: 00230+3.5.1.5|KEGG: 00791+3.5.1.5|MetaCyc: PWY-5704 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 Pfam PF01979 Amidohydrolase family 131 453 5.4E-67 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS02575 19acc0de6b5204a3ebe3df730aa41bd2 565 SUPERFAMILY SSF51338 424 477 5.61E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24980 a99eebb398ea6ea44276e45b9b34e397 307 SUPERFAMILY SSF47413 33 91 3.1E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS24980 a99eebb398ea6ea44276e45b9b34e397 307 SMART SM00530 40 95 2.5E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS24980 a99eebb398ea6ea44276e45b9b34e397 307 Pfam PF13560 Helix-turn-helix domain 36 98 6.4E-14 T 28-03-2018 CNX65_RS24980 a99eebb398ea6ea44276e45b9b34e397 307 Gene3D G3DSA:1.10.260.40 26 114 7.5E-12 T 28-03-2018 CNX65_RS03365 68bf41aafe89ffaf0610898dae77f9fb 541 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 461 7.0E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS03365 68bf41aafe89ffaf0610898dae77f9fb 541 Gene3D G3DSA:3.40.190.10 183 316 7.0E-33 T 28-03-2018 CNX65_RS03365 68bf41aafe89ffaf0610898dae77f9fb 541 Gene3D G3DSA:3.90.76.10 52 182 1.8E-23 T 28-03-2018 CNX65_RS03365 68bf41aafe89ffaf0610898dae77f9fb 541 SUPERFAMILY SSF53850 37 139 1.36E-102 T 28-03-2018 CNX65_RS03365 68bf41aafe89ffaf0610898dae77f9fb 541 SUPERFAMILY SSF53850 168 539 1.36E-102 T 28-03-2018 CNX65_RS03365 68bf41aafe89ffaf0610898dae77f9fb 541 Gene3D G3DSA:3.10.105.10 317 513 9.9E-45 T 28-03-2018 CNX65_RS03365 68bf41aafe89ffaf0610898dae77f9fb 541 PIRSF PIRSF002741 1 532 3.3E-81 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 Gene3D G3DSA:3.30.420.10 317 537 8.6E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 Pfam PF13482 RNase_H superfamily 317 499 2.6E-20 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 Gene3D G3DSA:3.40.50.300 942 1132 8.5E-23 T 28-03-2018 CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 14 500 1.5E-60 T 28-03-2018 IPR019993 RecB family nuclease, TM0106, putative CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 Gene3D G3DSA:3.40.50.300 741 922 6.2E-22 T 28-03-2018 CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 SUPERFAMILY SSF53098 341 500 1.82E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 SMART SM00382 756 938 1.6E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 SUPERFAMILY SSF52540 850 1118 5.56E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 SUPERFAMILY SSF52540 751 809 5.56E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 Pfam PF13604 AAA domain 758 913 8.0E-13 T 28-03-2018 CNX65_RS26405 26ef6eb4bcba5364235ff4b90eec9739 1153 Pfam PF13087 AAA domain 940 1112 2.4E-22 T 28-03-2018 CNX65_RS04745 8e1682ed33990062432e00d09e0b0a23 315 SUPERFAMILY SSF56112 17 286 1.76E-11 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS04745 8e1682ed33990062432e00d09e0b0a23 315 Gene3D G3DSA:1.10.510.10 133 277 1.4E-10 T 28-03-2018 CNX65_RS24620 0fabfc563b0675bcc08ca1d176458dad 332 Pfam PF00891 O-methyltransferase 95 316 7.2E-48 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CNX65_RS24620 0fabfc563b0675bcc08ca1d176458dad 332 Pfam PF16864 Dimerisation domain 3 84 1.1E-16 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CNX65_RS24620 0fabfc563b0675bcc08ca1d176458dad 332 SUPERFAMILY SSF53335 87 321 3.8E-47 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS24620 0fabfc563b0675bcc08ca1d176458dad 332 SUPERFAMILY SSF46785 3 76 1.03E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24620 0fabfc563b0675bcc08ca1d176458dad 332 Gene3D G3DSA:3.40.50.150 82 332 3.0E-43 T 28-03-2018 CNX65_RS24620 0fabfc563b0675bcc08ca1d176458dad 332 PIRSF PIRSF005739 1 327 3.3E-34 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CNX65_RS24620 0fabfc563b0675bcc08ca1d176458dad 332 Gene3D G3DSA:1.10.10.10 1 81 4.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 SUPERFAMILY SSF50331 279 361 8.42E-8 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 SUPERFAMILY SSF52540 18 257 1.27E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 Gene3D G3DSA:2.40.50.140 286 350 6.1E-6 T 28-03-2018 CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 Pfam PF08402 TOBE domain 283 355 1.7E-10 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 Pfam PF00005 ABC transporter 33 178 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 SMART SM00382 42 228 3.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS14395 9115b471f9ad484577bfdb807926bee2 365 Gene3D G3DSA:3.40.50.300 14 271 2.7E-69 T 28-03-2018 CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 SUPERFAMILY SSF52172 5 139 1.71E-27 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 Gene3D G3DSA:3.40.50.2300 2 123 1.4E-25 T 28-03-2018 CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 SUPERFAMILY SSF109604 136 366 1.04E-41 T 28-03-2018 CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 Gene3D G3DSA:1.10.3210.10 124 355 1.5E-28 T 28-03-2018 CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 SMART SM00448 5 117 7.2E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 Pfam PF08668 HDOD domain 142 333 1.3E-39 T 28-03-2018 IPR013976 Metal-dependent hydrolase HDOD CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 PIRSF PIRSF036883 1 367 2.7E-57 T 28-03-2018 IPR014626 Signal transduction response regulator with modified HD-GYP domain, putative CNX65_RS12055 a529e70a065f72fa8575adc86c66fb4c 403 Pfam PF00072 Response regulator receiver domain 7 117 2.0E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 Gene3D G3DSA:3.30.230.10 101 190 9.0E-29 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 36 187 1.7E-67 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 SUPERFAMILY SSF54768 35 100 1.05E-22 T 28-03-2018 CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 Pfam PF03719 Ribosomal protein S5, C-terminal domain 111 181 1.9E-27 T 28-03-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 4 187 34.436 T 28-03-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 Pfam PF00333 Ribosomal protein S5, N-terminal domain 37 99 3.5E-28 T 28-03-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 Gene3D G3DSA:3.30.160.20 36 95 2.5E-26 T 28-03-2018 CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 SUPERFAMILY SSF54211 103 182 1.92E-24 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS32365 538d2cf94ccc00173264dd553b0d7835 201 ProSitePatterns PS00585 Ribosomal protein S5 signature. 52 84 - T 28-03-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 Pfam PF01494 FAD binding domain 5 329 8.6E-41 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.1E-20 T 28-03-2018 CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 286 301 1.1E-20 T 28-03-2018 CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.1E-20 T 28-03-2018 CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 301 317 1.1E-20 T 28-03-2018 CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 SUPERFAMILY SSF51905 4 178 1.1E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 SUPERFAMILY SSF51905 282 385 1.1E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19885 cdddd910a12a1b3cd787bdcc575772b5 416 Gene3D G3DSA:3.50.50.60 4 362 3.7E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 Gene3D G3DSA:3.40.50.1000 22 263 3.4E-20 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 SUPERFAMILY SSF56784 24 250 8.25E-35 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 SUPERFAMILY SSF48208 461 840 6.05E-93 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 TIGRFAM TIGR00685 T6PP: trehalose-phosphatase 23 250 6.7E-37 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 Gene3D G3DSA:1.50.10.10 449 793 8.2E-78 T 28-03-2018 CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 Gene3D G3DSA:1.50.10.10 794 842 0.095 T 28-03-2018 CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 Pfam PF02358 Trehalose-phosphatase 27 217 2.0E-30 T 28-03-2018 IPR003337 Trehalose-phosphatase GO:0003824|GO:0005992 CNX65_RS01900 0fb699fed1e6e0cf11019ed1d8abaf1a 842 Pfam PF00723 Glycosyl hydrolases family 15 477 784 1.9E-35 T 28-03-2018 IPR011613 Glycoside hydrolase family 15/Phosphorylase b kinase regulatory chain family Reactome: R-HSA-70221 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 17 502 6.6E-144 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 Gene3D G3DSA:3.30.930.10 157 500 4.9E-85 T 28-03-2018 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 Gene3D G3DSA:2.40.50.140 16 156 9.9E-38 T 28-03-2018 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 Pfam PF00152 tRNA synthetases class II (D, K and N) 163 500 5.0E-67 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 22 503 35.486 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 Pfam PF01336 OB-fold nucleic acid binding domain 70 144 9.0E-10 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 244 257 3.1E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 386 402 3.1E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 199 209 3.1E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 215 231 3.1E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 PRINTS PR00982 Lysyl-tRNA synthetase signature 262 279 3.1E-32 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 SUPERFAMILY SSF50249 15 155 3.21E-35 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS01690 69ec5a677c8165ab51fc4d8be7ffe950 503 SUPERFAMILY SSF55681 163 501 1.35E-98 T 28-03-2018 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 Pfam PF00459 Inositol monophosphatase family 22 263 1.1E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 Gene3D G3DSA:3.30.540.10 16 157 9.6E-33 T 28-03-2018 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 Gene3D G3DSA:3.40.190.80 158 274 7.0E-18 T 28-03-2018 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 SUPERFAMILY SSF56655 21 267 8.9E-47 T 28-03-2018 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 96 112 1.8E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 219 243 1.8E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 145 168 1.8E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 53 73 1.8E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS32945 7b56a8172a933559b753b644a0867438 274 PRINTS PR00377 Inositol monophosphatase superfamily signature 188 209 1.8E-18 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31860 b629736e59de51899643ab75b88dae88 204 Pfam PF13599 Pentapeptide repeats (9 copies) 49 118 2.4E-10 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS31860 b629736e59de51899643ab75b88dae88 204 Gene3D G3DSA:2.160.10.20 3 105 2.8E-16 T 28-03-2018 CNX65_RS31860 b629736e59de51899643ab75b88dae88 204 Gene3D G3DSA:3.30.1120.50 106 135 3.0E-8 T 28-03-2018 CNX65_RS31860 b629736e59de51899643ab75b88dae88 204 Gene3D G3DSA:3.30.1120.50 136 197 3.8E-15 T 28-03-2018 CNX65_RS31860 b629736e59de51899643ab75b88dae88 204 SUPERFAMILY SSF141571 29 202 2.85E-43 T 28-03-2018 CNX65_RS31860 b629736e59de51899643ab75b88dae88 204 Pfam PF00805 Pentapeptide repeats (8 copies) 134 171 2.5E-13 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 194 1.1E-34 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 Gene3D G3DSA:3.40.50.1220 208 369 1.1E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 SUPERFAMILY SSF52467 179 378 1.14E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 SUPERFAMILY SSF52518 391 580 5.16E-30 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 SUPERFAMILY SSF52518 1 208 6.38E-28 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 434 571 2.8E-22 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 TIGRFAM TIGR04377 myo_inos_iolD: 3,5/4-trihydroxycyclohexa-1,2-dione hydrolase 2 593 4.1E-224 T 28-03-2018 IPR030817 3,5/4-Trihydroxycyclohexa-1,2-dione hydrolase GO:0016823|GO:0019310|GO:0030976 KEGG: 00562+3.7.1.22 CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 Gene3D G3DSA:3.40.50.970 1 205 4.9E-39 T 28-03-2018 CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 Gene3D G3DSA:3.40.50.970 370 581 2.0E-25 T 28-03-2018 CNX65_RS33840 36ee66c6f0ef3d33c6d0ba2cfcd50df2 616 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 218 350 9.0E-32 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 SUPERFAMILY SSF52540 166 464 2.05E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Pfam PF01926 50S ribosome-binding GTPase 34 148 3.6E-24 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Pfam PF01926 50S ribosome-binding GTPase 208 326 7.6E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 382 460 1.1E-26 T 28-03-2018 IPR032859 GTPase Der, C-terminal KH-domain-like CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Gene3D G3DSA:3.30.300.20 376 461 1.3E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 PIRSF PIRSF006485 30 468 1.1E-160 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 SUPERFAMILY SSF52540 33 195 5.67E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 32 460 4.6E-155 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Gene3D G3DSA:1.20.120.430 97 260 9.8E-38 T 28-03-2018 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Gene3D G3DSA:1.20.120.430 15 96 2.0E-17 T 28-03-2018 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 SMART SM00382 205 450 3.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 SMART SM00382 30 168 0.39 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 209 229 3.0E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 258 273 3.0E-7 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Hamap MF_00195 GTPase Der [der]. 31 463 35.047 T 28-03-2018 IPR016484 GTP-binding protein EngA GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 33 153 2.8E-22 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 207 364 5.1E-19 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS08020 0336694c2e85b85eaaf5b488b6ee5852 471 Gene3D G3DSA:3.40.50.300 261 358 2.0E-10 T 28-03-2018 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 Gene3D G3DSA:3.30.565.10 205 369 5.7E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 SUPERFAMILY SSF55874 204 361 1.83E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 358 2.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 299 2.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 PRINTS PR00344 Bacterial sensor protein C-terminal signature 321 339 2.4E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 SMART SM00387 245 361 1.0E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 SMART SM00304 85 138 4.9E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 249 360 5.8E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 SUPERFAMILY SSF47384 122 204 7.46E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 SMART SM00388 139 203 3.0E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 Pfam PF00512 His Kinase A (phospho-acceptor) domain 140 203 2.4E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 Pfam PF00672 HAMP domain 86 134 9.9E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 Gene3D G3DSA:1.10.287.130 129 199 1.3E-12 T 28-03-2018 CNX65_RS22450 a3dac494f9f5c396c72d16dfb6d5771a 380 SUPERFAMILY SSF158472 86 135 1.7E-8 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 308 315 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 144 153 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 279 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 41 56 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 430 450 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 408 423 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 343 364 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.5E-56 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 Gene3D G3DSA:3.30.390.30 337 465 2.6E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 455 1.8E-25 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 SUPERFAMILY SSF55424 347 463 2.23E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 Gene3D G3DSA:3.40.50.720 172 336 4.8E-33 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PIRSF PIRSF000350 1 468 4.5E-71 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 293 315 2.1E-31 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 280 2.1E-31 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 2.1E-31 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 2.1E-31 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 2.1E-31 T 28-03-2018 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 SUPERFAMILY SSF51905 2 337 1.39E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 Gene3D G3DSA:3.50.50.60 1 171 2.3E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS27205 6b08415d247ab0e92a255e63ce44a4df 471 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 328 1.1E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28605 14dc93eced884e223bfbf536109ca5f5 149 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 3 114 5.1E-22 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CNX65_RS28605 14dc93eced884e223bfbf536109ca5f5 149 Gene3D G3DSA:3.30.300.20 4 120 2.5E-28 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS28605 14dc93eced884e223bfbf536109ca5f5 149 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 9 100 1.0E-25 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CNX65_RS28605 14dc93eced884e223bfbf536109ca5f5 149 SUPERFAMILY SSF89919 3 116 1.05E-27 T 28-03-2018 IPR023799 Ribosome-binding factor A domain CNX65_RS28605 14dc93eced884e223bfbf536109ca5f5 149 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 2 120 18.709 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CNX65_RS28605 14dc93eced884e223bfbf536109ca5f5 149 ProSitePatterns PS01319 Ribosome-binding factor A signature. 79 100 - T 28-03-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 CNX65_RS28605 14dc93eced884e223bfbf536109ca5f5 149 Pfam PF02033 Ribosome-binding factor A 6 113 1.6E-25 T 28-03-2018 IPR000238 Ribosome-binding factor A GO:0006364 CNX65_RS28160 23ec6675070352e6366e57d34f6ffd30 294 Gene3D G3DSA:3.30.2350.10 67 294 2.5E-65 T 28-03-2018 CNX65_RS28160 23ec6675070352e6366e57d34f6ffd30 294 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 2 291 3.1E-84 T 28-03-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28160 23ec6675070352e6366e57d34f6ffd30 294 Pfam PF00849 RNA pseudouridylate synthase 75 229 3.9E-35 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28160 23ec6675070352e6366e57d34f6ffd30 294 SUPERFAMILY SSF55120 63 291 2.88E-72 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28160 23ec6675070352e6366e57d34f6ffd30 294 SUPERFAMILY SSF55174 1 51 8.24E-5 T 28-03-2018 CNX65_RS28160 23ec6675070352e6366e57d34f6ffd30 294 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 121 135 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28160 23ec6675070352e6366e57d34f6ffd30 294 Gene3D G3DSA:3.10.290.10 1 57 2.9E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 23 74 2.0E-19 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 SUPERFAMILY SSF46911 1 75 3.53E-25 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 75 19.193 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 73 1.2E-22 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 Pfam PF01084 Ribosomal protein S18 22 70 9.8E-23 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 PRINTS PR00974 Ribosomal protein S18 family signature 40 47 8.1E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 PRINTS PR00974 Ribosomal protein S18 family signature 48 62 8.1E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 PRINTS PR00974 Ribosomal protein S18 family signature 30 40 8.1E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 PRINTS PR00974 Ribosomal protein S18 family signature 62 72 8.1E-18 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03000 c4b5290ad729b95e84d0f8427644721c 77 Gene3D G3DSA:4.10.640.10 1 77 1.5E-28 T 28-03-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 3 238 4.6E-106 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 Gene3D G3DSA:3.30.230.70 1 242 2.8E-55 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 Pfam PF01138 3' exoribonuclease family, domain 1 12 141 4.2E-21 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 SUPERFAMILY SSF55666 156 244 7.59E-22 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 ProSitePatterns PS01277 Ribonuclease PH signature. 117 130 - T 28-03-2018 IPR018336 Ribonuclease PH, conserved site CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 Hamap MF_00564 Ribonuclease PH [rph]. 2 239 44.901 T 28-03-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 SUPERFAMILY SSF54211 2 183 6.07E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS05115 1432bd48670826b8dcc5fdbc94566d4f 254 Pfam PF03725 3' exoribonuclease family, domain 2 160 226 3.3E-10 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Gene3D G3DSA:2.60.40.1220 824 919 3.4E-8 T 28-03-2018 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Gene3D G3DSA:2.60.40.1220 1366 1461 1.9E-10 T 28-03-2018 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Gene3D G3DSA:2.60.40.1220 1097 1193 1.2E-9 T 28-03-2018 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Pfam PF13205 Bacterial Ig-like domain 1361 1461 3.6E-13 T 28-03-2018 IPR032812 SbsA, Ig-like domain CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Pfam PF13205 Bacterial Ig-like domain 1093 1193 7.9E-19 T 28-03-2018 IPR032812 SbsA, Ig-like domain CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Pfam PF13205 Bacterial Ig-like domain 821 919 8.0E-14 T 28-03-2018 IPR032812 SbsA, Ig-like domain CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Pfam PF13313 Domain of unknown function (DUF4082) 653 810 5.2E-56 T 28-03-2018 IPR025141 Domain of unknown function DUF4082 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Pfam PF13313 Domain of unknown function (DUF4082) 1203 1352 1.8E-57 T 28-03-2018 IPR025141 Domain of unknown function DUF4082 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Pfam PF13313 Domain of unknown function (DUF4082) 1471 1620 7.0E-56 T 28-03-2018 IPR025141 Domain of unknown function DUF4082 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Pfam PF13313 Domain of unknown function (DUF4082) 931 1082 2.1E-56 T 28-03-2018 IPR025141 Domain of unknown function DUF4082 CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 SUPERFAMILY SSF81296 568 634 9.7E-11 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS08660 904b5c8e3c2b2c8330dcf421a9871c16 1627 Gene3D G3DSA:2.60.40.650 553 656 4.6E-14 T 28-03-2018 CNX65_RS26560 318d3e7c8f4a9562c328c698c450cb22 262 Gene3D G3DSA:2.70.50.50 31 171 1.6E-30 T 28-03-2018 CNX65_RS26560 318d3e7c8f4a9562c328c698c450cb22 262 SUPERFAMILY SSF51055 218 261 1.96E-14 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CNX65_RS26560 318d3e7c8f4a9562c328c698c450cb22 262 Gene3D G3DSA:2.10.10.20 219 261 1.2E-13 T 28-03-2018 CNX65_RS26560 318d3e7c8f4a9562c328c698c450cb22 262 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 31 168 1.7E-16 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CNX65_RS26560 318d3e7c8f4a9562c328c698c450cb22 262 SMART SM00495 216 262 4.7E-6 T 28-03-2018 IPR003610 Carbohydrate-binding module family 5/12 GO:0004553|GO:0005576|GO:0005975|GO:0030246 CNX65_RS26560 318d3e7c8f4a9562c328c698c450cb22 262 SUPERFAMILY SSF81296 31 171 8.54E-35 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 108 5.7E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 Gene3D G3DSA:1.20.140.10 207 371 1.2E-33 T 28-03-2018 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 Gene3D G3DSA:2.40.110.10 111 206 4.3E-28 T 28-03-2018 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 Gene3D G3DSA:1.10.540.10 2 110 7.6E-17 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 114 126 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 SUPERFAMILY SSF56645 8 217 1.06E-47 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 366 3.3E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 SUPERFAMILY SSF47203 224 367 1.21E-33 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS16210 c8b62c92eafaa354fa1e144899aeb479 371 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 112 205 5.6E-18 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS09605 de39ee18994bba3e461dcab010ec2bfc 266 Pfam PF00535 Glycosyl transferase family 2 19 183 1.7E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS09605 de39ee18994bba3e461dcab010ec2bfc 266 SUPERFAMILY SSF53448 15 227 4.5E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS09605 de39ee18994bba3e461dcab010ec2bfc 266 Gene3D G3DSA:3.90.550.10 4 262 9.3E-29 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 Pfam PF01595 Domain of unknown function DUF21 10 187 2.0E-32 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 SUPERFAMILY SSF56176 338 429 5.18E-15 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 Gene3D G3DSA:3.10.580.10 183 332 8.3E-34 T 28-03-2018 CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 Gene3D G3DSA:3.30.465.10 333 421 3.3E-23 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 SMART SM01091 339 421 2.8E-19 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 Pfam PF00571 CBS domain 204 258 2.6E-5 T 28-03-2018 IPR000644 CBS domain CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 Pfam PF00571 CBS domain 269 323 1.6E-7 T 28-03-2018 IPR000644 CBS domain CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 SUPERFAMILY SSF54631 189 326 9.98E-34 T 28-03-2018 CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 SMART SM00116 275 323 5.6 T 28-03-2018 IPR000644 CBS domain CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 SMART SM00116 211 260 2.8 T 28-03-2018 IPR000644 CBS domain CNX65_RS06235 f6f42200cdbb43cb0130bac6439d3aa5 434 Pfam PF03471 Transporter associated domain 341 417 2.3E-12 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 318 333 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 191 213 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 272 283 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 349 360 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 90 101 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 340 349 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 137 153 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 154 169 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00359 B-class P450 signature 290 317 2.1E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 SUPERFAMILY SSF48264 5 400 7.2E-91 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00385 P450 superfamily signature 349 360 1.3E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00385 P450 superfamily signature 272 283 1.3E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00385 P450 superfamily signature 340 349 1.3E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 PRINTS PR00385 P450 superfamily signature 237 254 1.3E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 Pfam PF00067 Cytochrome P450 203 369 4.3E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS15295 ddf7bf4669d0de525e504005a0057601 400 Gene3D G3DSA:1.10.630.10 1 400 4.0E-67 T 28-03-2018 CNX65_RS14635 0ba1b4245c00be27d3c920a29433100a 482 SUPERFAMILY SSF51338 372 425 3.56E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS14635 0ba1b4245c00be27d3c920a29433100a 482 SUPERFAMILY SSF51338 6 62 3.56E-22 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS14635 0ba1b4245c00be27d3c920a29433100a 482 SUPERFAMILY SSF51556 61 373 1.68E-56 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS14635 0ba1b4245c00be27d3c920a29433100a 482 Gene3D G3DSA:2.30.40.10 7 74 1.6E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS14635 0ba1b4245c00be27d3c920a29433100a 482 Gene3D G3DSA:2.30.40.10 355 424 5.2E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS14635 0ba1b4245c00be27d3c920a29433100a 482 Pfam PF01979 Amidohydrolase family 58 421 5.5E-29 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS14635 0ba1b4245c00be27d3c920a29433100a 482 Gene3D G3DSA:3.20.20.140 75 354 8.8E-39 T 28-03-2018 CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 Pfam PF13378 Enolase C-terminal domain-like 197 411 4.3E-60 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 Gene3D G3DSA:3.20.20.120 175 431 1.8E-68 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 36 131 4.3E-6 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 SUPERFAMILY SSF51604 179 425 5.5E-68 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 SUPERFAMILY SSF54826 1 134 2.19E-34 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 SMART SM00922 194 290 9.7E-25 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 240 271 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CNX65_RS02025 27a021be4bb78671b57b6c50c83b13d7 431 Gene3D G3DSA:3.30.390.10 1 174 1.0E-37 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 SMART SM00482 313 514 7.0E-10 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 Pfam PF00476 DNA polymerase family A 207 531 1.3E-23 T 28-03-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 PRINTS PR00868 DNA-polymerase family A (pol I) signature 467 483 1.7E-5 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 PRINTS PR00868 DNA-polymerase family A (pol I) signature 497 510 1.7E-5 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 PRINTS PR00868 DNA-polymerase family A (pol I) signature 327 350 1.7E-5 T 28-03-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 Gene3D G3DSA:3.30.70.370 290 377 2.1E-11 T 28-03-2018 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 SUPERFAMILY SSF56672 157 554 4.23E-63 T 28-03-2018 CNX65_RS05410 6f2c8374e1cf9604bf1fefee7c52439c 555 Gene3D G3DSA:3.30.70.370 378 555 6.0E-21 T 28-03-2018 CNX65_RS24025 9437dba2872ce6f3b7fda109baa86594 300 Gene3D G3DSA:3.40.50.720 13 143 1.3E-15 T 28-03-2018 CNX65_RS24025 9437dba2872ce6f3b7fda109baa86594 300 Pfam PF13460 NAD(P)H-binding 25 112 7.2E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24025 9437dba2872ce6f3b7fda109baa86594 300 Gene3D G3DSA:3.40.50.720 144 254 8.2E-10 T 28-03-2018 CNX65_RS24025 9437dba2872ce6f3b7fda109baa86594 300 SUPERFAMILY SSF51735 19 282 1.42E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24025 9437dba2872ce6f3b7fda109baa86594 300 Pfam PF05368 NmrA-like family 134 224 5.4E-6 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 SUPERFAMILY SSF51735 9 248 2.24E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 247 9.7E-65 T 28-03-2018 CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 11 28 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 212 232 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 2.8E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 Gene3D G3DSA:3.40.50.720 47 250 1.1E-61 T 28-03-2018 CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 Gene3D G3DSA:3.40.50.720 2 46 7.0E-11 T 28-03-2018 CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 1.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 1.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 10 186 1.4E-4 T 28-03-2018 CNX65_RS34815 825bc4620e702d531a0744a89660483d 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS33755 9b67420c2dd561087146baecc93b05bc 140 Gene3D G3DSA:3.40.30.10 36 139 2.6E-13 T 28-03-2018 CNX65_RS33755 9b67420c2dd561087146baecc93b05bc 140 Pfam PF00085 Thioredoxin 47 125 2.5E-5 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CNX65_RS33755 9b67420c2dd561087146baecc93b05bc 140 SUPERFAMILY SSF52833 43 134 1.24E-14 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS20725 32010ac7f8dc73a0dc0950c6fe3f280f 321 SUPERFAMILY SSF51182 38 304 7.69E-65 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS20725 32010ac7f8dc73a0dc0950c6fe3f280f 321 Gene3D G3DSA:2.60.120.10 34 265 3.3E-57 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS20725 32010ac7f8dc73a0dc0950c6fe3f280f 321 Pfam PF02678 Pirin 40 139 3.4E-29 T 28-03-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 CNX65_RS20725 32010ac7f8dc73a0dc0950c6fe3f280f 321 Pfam PF05726 Pirin C-terminal cupin domain 191 289 8.0E-15 T 28-03-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 CNX65_RS20725 32010ac7f8dc73a0dc0950c6fe3f280f 321 PIRSF PIRSF006232 17 301 5.6E-73 T 28-03-2018 IPR012093 Pirin Reactome: R-HSA-8935690 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 4.2E-99 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 2.3E-217 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 Gene3D G3DSA:1.20.210.10 26 536 1.5E-195 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 SUPERFAMILY SSF81442 25 535 2.88E-176 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS11205 53c5829ea8fa29beaf010a676d987b1f 589 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 480 3.4E-150 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 SUPERFAMILY SSF53623 137 363 7.59E-64 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 35 522 30.956 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 SUPERFAMILY SSF53244 365 524 4.06E-42 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 Pfam PF01225 Mur ligase family, catalytic domain 58 134 8.4E-11 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 Pfam PF02875 Mur ligase family, glutamate ligase domain 365 450 7.8E-19 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 SUPERFAMILY SSF63418 51 135 3.14E-19 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 58 519 3.5E-139 T 28-03-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 Gene3D G3DSA:3.90.190.20 369 526 4.6E-41 T 28-03-2018 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 Pfam PF08245 Mur ligase middle domain 146 345 9.5E-42 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 Gene3D G3DSA:3.40.1190.10 137 368 1.7E-56 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28275 843a6fdaefb95acb92eb9ca5df9960f0 527 Gene3D G3DSA:3.40.1390.10 33 136 8.6E-25 T 28-03-2018 CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 Pfam PF01555 DNA methylase 172 234 3.9E-13 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 Pfam PF01555 DNA methylase 23 153 5.0E-11 T 28-03-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 Gene3D G3DSA:3.40.50.150 2 246 2.4E-43 T 28-03-2018 CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 SUPERFAMILY SSF53335 64 238 2.53E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 SUPERFAMILY SSF53335 4 36 2.53E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 22 36 5.4E-19 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 82 102 5.4E-19 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 218 238 5.4E-19 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CNX65_RS25140 2fb568df0f21465eb8e7c0a553467c2c 246 PRINTS PR00508 S21 class N4 adenine-specific DNA methyltransferase signature 195 213 5.4E-19 T 28-03-2018 IPR001091 Restriction/modification DNA-methylase GO:0003677|GO:0006306|GO:0008170 CNX65_RS33370 a41b9198447ae1fdb69c1cfd6ac1a5e7 182 Gene3D G3DSA:3.40.50.880 1 181 8.2E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS33370 a41b9198447ae1fdb69c1cfd6ac1a5e7 182 Pfam PF01965 DJ-1/PfpI family 6 178 1.2E-46 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS33370 a41b9198447ae1fdb69c1cfd6ac1a5e7 182 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 8 180 1.2E-48 T 28-03-2018 IPR006286 Peptidase C56, PfpI CNX65_RS33370 a41b9198447ae1fdb69c1cfd6ac1a5e7 182 SUPERFAMILY SSF52317 6 181 5.7E-43 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 SUPERFAMILY SSF117074 64 144 7.06E-14 T 28-03-2018 CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 Pfam PF00652 Ricin-type beta-trefoil lectin domain 247 333 1.3E-9 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 Gene3D G3DSA:2.80.10.50 292 334 2.3E-7 T 28-03-2018 CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 Pfam PF17210 SdrD B-like domain 71 168 7.4E-12 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 SMART SM00458 191 333 1.4E-6 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 SUPERFAMILY SSF50370 191 332 5.03E-20 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 Gene3D G3DSA:2.80.10.50 191 291 4.2E-14 T 28-03-2018 CNX65_RS20755 0100930fa2bb743b3b05e7c5867d7327 334 Gene3D G3DSA:2.60.40.1120 65 154 3.4E-7 T 28-03-2018 CNX65_RS04935 5d65ca044a3a85acc8415042e137c87e 351 Gene3D G3DSA:3.40.50.10470 149 345 3.4E-48 T 28-03-2018 CNX65_RS04935 5d65ca044a3a85acc8415042e137c87e 351 Gene3D G3DSA:1.20.120.420 14 148 4.5E-17 T 28-03-2018 IPR027363 Methylthioribose-1-phosphate isomerase-like, N-terminal domain KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CNX65_RS04935 5d65ca044a3a85acc8415042e137c87e 351 Pfam PF01008 Initiation factor 2 subunit family 68 329 3.7E-44 T 28-03-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 CNX65_RS04935 5d65ca044a3a85acc8415042e137c87e 351 SUPERFAMILY SSF100950 15 337 1.26E-70 T 28-03-2018 CNX65_RS00940 93fddddb1bb4aac537e0e311b36c05a5 156 Gene3D G3DSA:3.40.50.300 17 156 5.1E-12 T 28-03-2018 CNX65_RS00940 93fddddb1bb4aac537e0e311b36c05a5 156 SUPERFAMILY SSF52540 3 154 2.67E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00940 93fddddb1bb4aac537e0e311b36c05a5 156 Gene3D G3DSA:3.40.50.300 1 16 3.0E-4 T 28-03-2018 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 PRINTS PR01011 Glutathione peroxidase family signature 56 72 1.1E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 PRINTS PR01011 Glutathione peroxidase family signature 21 38 1.1E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 PRINTS PR01011 Glutathione peroxidase family signature 122 131 1.1E-19 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 PIRSF PIRSF000303 1 163 1.6E-62 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 Pfam PF00255 Glutathione peroxidase 3 109 1.3E-41 T 28-03-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 Gene3D G3DSA:3.40.30.10 1 162 2.0E-44 T 28-03-2018 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 28-03-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 SUPERFAMILY SSF52833 1 160 8.47E-55 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS30740 a9d0c39c33f285db52af209ef830800b 163 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 28-03-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 CNX65_RS21105 576e84f2d3b643ec442dd7d527f31463 300 SUPERFAMILY SSF53850 88 289 1.47E-37 T 28-03-2018 CNX65_RS21105 576e84f2d3b643ec442dd7d527f31463 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS21105 576e84f2d3b643ec442dd7d527f31463 300 Gene3D G3DSA:1.10.10.10 2 83 1.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21105 576e84f2d3b643ec442dd7d527f31463 300 Gene3D G3DSA:3.40.190.10 182 265 1.9E-16 T 28-03-2018 CNX65_RS21105 576e84f2d3b643ec442dd7d527f31463 300 SUPERFAMILY SSF46785 2 82 4.24E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21105 576e84f2d3b643ec442dd7d527f31463 300 Pfam PF03466 LysR substrate binding domain 108 290 3.4E-23 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS21105 576e84f2d3b643ec442dd7d527f31463 300 Gene3D G3DSA:3.40.190.10 98 181 6.2E-11 T 28-03-2018 CNX65_RS24460 3a9ee14f85e47e002d7cb92792ad294e 262 SUPERFAMILY SSF54637 158 261 2.42E-6 T 28-03-2018 IPR029069 HotDog domain CNX65_RS24460 3a9ee14f85e47e002d7cb92792ad294e 262 Gene3D G3DSA:3.10.129.10 149 261 5.6E-6 T 28-03-2018 CNX65_RS24460 3a9ee14f85e47e002d7cb92792ad294e 262 SUPERFAMILY SSF54637 6 109 4.91E-13 T 28-03-2018 IPR029069 HotDog domain CNX65_RS24460 3a9ee14f85e47e002d7cb92792ad294e 262 Gene3D G3DSA:3.10.129.10 1 107 1.1E-20 T 28-03-2018 CNX65_RS24460 3a9ee14f85e47e002d7cb92792ad294e 262 Pfam PF13622 Thioesterase-like superfamily 24 258 8.2E-39 T 28-03-2018 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 SUPERFAMILY SSF52540 9 230 4.06E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 SUPERFAMILY SSF52540 516 556 4.06E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 PRINTS PR00906 SecA protein signature 66 90 1.2E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 PRINTS PR00906 SecA protein signature 104 118 1.2E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 PRINTS PR00906 SecA protein signature 324 346 1.2E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 PRINTS PR00906 SecA protein signature 173 193 1.2E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 PRINTS PR00906 SecA protein signature 361 378 1.2E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 PRINTS PR00906 SecA protein signature 398 411 1.2E-35 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Pfam PF07516 SecA Wing and Scaffold domain 641 722 1.2E-14 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Hamap MF_01382 Protein translocase subunit SecA [secA]. 11 727 15.217 T 28-03-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Gene3D G3DSA:3.40.50.300 16 253 2.8E-31 T 28-03-2018 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Gene3D G3DSA:1.10.3060.10 595 735 2.1E-21 T 28-03-2018 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 ProSitePatterns PS01312 SecA family signature. 485 500 - T 28-03-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 SUPERFAMILY SSF81767 241 351 5.75E-30 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 SUPERFAMILY SSF52540 404 565 1.46E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Pfam PF01043 SecA preprotein cross-linking domain 242 343 2.7E-22 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Pfam PF07517 SecA DEAD-like domain 15 386 1.9E-81 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 SUPERFAMILY SSF81886 585 734 7.72E-29 T 28-03-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Gene3D G3DSA:3.40.50.300 402 594 4.4E-34 T 28-03-2018 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 TIGRFAM TIGR04221 SecA2_Mycobac: accessory Sec system translocase SecA2 11 770 0.0 T 28-03-2018 IPR026389 Protein translocase subunit SecA, Actinobacteria-type CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 SMART SM00957 12 387 1.3E-134 T 28-03-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 Gene3D G3DSA:3.90.1440.10 254 353 1.3E-28 T 28-03-2018 CNX65_RS07910 12a2a225b2b05bbef53c19ce2c5eba5a 772 SMART SM00958 235 343 2.3E-27 T 28-03-2018 IPR011130 SecA preprotein, cross-linking domain GO:0016020|GO:0017038 CNX65_RS19685 8812fadcbb41f96f9ac0e3046033a67a 269 Gene3D G3DSA:3.10.310.10 2 127 1.7E-7 T 28-03-2018 CNX65_RS19685 8812fadcbb41f96f9ac0e3046033a67a 269 Gene3D G3DSA:3.10.310.10 128 258 3.8E-8 T 28-03-2018 CNX65_RS19685 8812fadcbb41f96f9ac0e3046033a67a 269 SUPERFAMILY SSF54506 31 268 4.93E-12 T 28-03-2018 CNX65_RS29160 4d613fc1cbae0fc205143709af21ae95 177 Pfam PF14430 Immunity protein Imm1 45 159 5.3E-20 T 28-03-2018 IPR025680 Immunity protein Imm1 CNX65_RS29525 fa05f4dca4ab8af429382574624970bd 200 Pfam PF00694 Aconitase C-terminal domain 1 115 1.5E-22 T 28-03-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain GO:0008152 KEGG: 00290+4.2.1.33 CNX65_RS29525 fa05f4dca4ab8af429382574624970bd 200 SUPERFAMILY SSF52016 1 188 2.94E-51 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CNX65_RS29525 fa05f4dca4ab8af429382574624970bd 200 Gene3D G3DSA:3.20.19.10 1 168 8.3E-45 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CNX65_RS29525 fa05f4dca4ab8af429382574624970bd 200 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 191 38.574 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CNX65_RS29525 fa05f4dca4ab8af429382574624970bd 200 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 1 180 1.5E-53 T 28-03-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 SUPERFAMILY SSF54862 98 234 3.1E-31 T 28-03-2018 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Gene3D G3DSA:3.40.50.740 465 687 4.6E-32 T 28-03-2018 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 18 95 9.3E-15 T 28-03-2018 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Gene3D G3DSA:2.40.40.20 727 813 4.8E-16 T 28-03-2018 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 ProSitePatterns PS00641 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. 47 64 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 SUPERFAMILY SSF53706 229 725 5.56E-75 T 28-03-2018 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Gene3D G3DSA:3.10.20.30 9 186 6.2E-13 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Pfam PF01568 Molydopterin dinucleotide binding domain 728 792 1.1E-8 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 TIGRFAM TIGR01973 NuoG: NADH dehydrogenase (quinone), G subunit 21 654 2.3E-167 T 28-03-2018 IPR010228 NADH:ubiquinone oxidoreductase, subunit G GO:0016651|GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Pfam PF10588 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region 106 144 1.2E-15 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 SUPERFAMILY SSF54292 18 94 3.07E-16 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Gene3D G3DSA:3.40.50.740 296 464 8.3E-22 T 28-03-2018 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Gene3D G3DSA:2.20.25.90 238 293 4.4E-8 T 28-03-2018 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Pfam PF00384 Molybdopterin oxidoreductase 497 646 4.9E-9 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 Pfam PF00384 Molybdopterin oxidoreductase 295 439 2.9E-11 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 ProSitePatterns PS00643 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. 168 178 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 SMART SM00926 238 292 0.0094 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 ProSitePatterns PS00642 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. 120 132 - T 28-03-2018 IPR000283 NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site GO:0008137|GO:0016020|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 SUPERFAMILY SSF50692 708 791 2.28E-11 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CNX65_RS32900 992c6f13889f72bbccac0fe035e2babe 815 SMART SM00929 105 145 7.8E-19 T 28-03-2018 IPR019574 NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS03820 7052f3ccc0473794a7fd8a0a93108f17 255 Pfam PF03641 Possible lysine decarboxylase 114 242 2.1E-32 T 28-03-2018 IPR031100 LOG family CNX65_RS03820 7052f3ccc0473794a7fd8a0a93108f17 255 Gene3D G3DSA:3.40.50.450 48 254 3.2E-69 T 28-03-2018 CNX65_RS03820 7052f3ccc0473794a7fd8a0a93108f17 255 SUPERFAMILY SSF102405 42 244 8.39E-62 T 28-03-2018 CNX65_RS03820 7052f3ccc0473794a7fd8a0a93108f17 255 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 72 245 1.3E-43 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 Pfam PF01220 Dehydroquinase class II 3 138 3.5E-56 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 Gene3D G3DSA:3.40.50.9100 1 145 4.3E-61 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 ProSitePatterns PS01029 Dehydroquinase class II signature. 6 23 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 3 138 1.0E-49 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 3 141 1.2E-59 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 146 64.645 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 PIRSF PIRSF001399 1 145 5.6E-59 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26140 29f0847c32b12d357d4c65d01d99da4a 146 SUPERFAMILY SSF52304 2 142 2.22E-57 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Gene3D G3DSA:3.30.56.50 6 47 1.2E-11 T 28-03-2018 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Gene3D G3DSA:3.30.56.50 447 486 0.022 T 28-03-2018 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 SUPERFAMILY SSF52540 527 693 3.71E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 529 688 1.0E-32 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 438 1030 4.4E-228 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Pfam PF00009 Elongation factor Tu GTP binding domain 531 691 4.4E-33 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 SUPERFAMILY SSF52156 811 938 7.98E-35 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Gene3D G3DSA:3.40.50.300 522 704 3.8E-37 T 28-03-2018 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 SUPERFAMILY SSF50447 705 787 2.55E-23 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 447 491 1.0E-5 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 4 50 5.9E-13 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 ProSitePatterns PS01176 Initiation factor 2 signature. 983 1005 - T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 SUPERFAMILY SSF50447 932 1030 2.16E-28 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 PRINTS PR00315 GTP-binding elongation factor signature 598 609 2.5E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 PRINTS PR00315 GTP-binding elongation factor signature 634 643 2.5E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 PRINTS PR00315 GTP-binding elongation factor signature 530 543 2.5E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 PRINTS PR00315 GTP-binding elongation factor signature 582 592 2.5E-9 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 4 1030 16.898 T 28-03-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Gene3D G3DSA:2.40.30.10 932 1031 1.1E-28 T 28-03-2018 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Pfam PF11987 Translation-initiation factor 2 819 921 1.0E-31 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Gene3D G3DSA:3.40.50.10050 834 910 5.2E-23 T 28-03-2018 IPR023115 Translation initiation factor IF- 2, domain 3 CNX65_RS28615 ff7bacc3900310f1be5ab85505d2efcf 1031 Gene3D G3DSA:2.40.30.10 705 833 4.6E-34 T 28-03-2018 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 SMART SM00422 7 76 1.4E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 Gene3D G3DSA:1.10.1660.10 62 135 2.2E-6 T 28-03-2018 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 Gene3D G3DSA:1.10.1660.10 2 61 5.5E-19 T 28-03-2018 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 Pfam PF13411 MerR HTH family regulatory protein 7 74 1.4E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 1.6E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS15125 9e5bed6205c388204023e711d9347491 336 SUPERFAMILY SSF46955 7 112 1.76E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS30695 af8717ae778b5d13dc0d278a9e280738 382 SUPERFAMILY SSF55874 290 378 2.58E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30695 af8717ae778b5d13dc0d278a9e280738 382 Gene3D G3DSA:3.30.565.10 235 382 5.8E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30695 af8717ae778b5d13dc0d278a9e280738 382 Pfam PF07730 Histidine kinase 192 256 5.7E-17 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS30695 af8717ae778b5d13dc0d278a9e280738 382 SMART SM00387 289 380 1.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12010 e29c39a8ef5cd03f92d278816ea2a39c 170 SUPERFAMILY SSF141457 22 141 4.71E-32 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain CNX65_RS12010 e29c39a8ef5cd03f92d278816ea2a39c 170 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 21 144 18.677 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CNX65_RS12010 e29c39a8ef5cd03f92d278816ea2a39c 170 Pfam PF02623 FliW protein 23 141 2.9E-30 T 28-03-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 CNX65_RS12010 e29c39a8ef5cd03f92d278816ea2a39c 170 Gene3D G3DSA:2.30.290.10 10 149 1.2E-35 T 28-03-2018 IPR024046 Flagellar assembly factor FliW domain CNX65_RS17235 2224e039a7ca252bc8c365544d2131c2 62 Pfam PF04024 PspC domain 5 59 1.2E-19 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 Gene3D G3DSA:3.30.70.80 37 114 1.2E-15 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 Pfam PF05922 Peptidase inhibitor I9 64 106 2.5E-4 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 SUPERFAMILY SSF52743 115 376 3.4E-68 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 147 158 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 Gene3D G3DSA:3.40.50.200 115 391 9.5E-71 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 182 192 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 178 191 7.1E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 142 161 7.1E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 PRINTS PR00723 Subtilisin serine protease family (S8) signature 334 350 7.1E-15 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 Pfam PF00082 Subtilase family 154 369 2.9E-34 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 SUPERFAMILY SSF54897 44 110 4.19E-9 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS10045 a47237a4d711e596eb13fc584f7a2ee2 514 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 335 345 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS30605 c8b4b6cfc0fdaebfccd07535208a6208 158 Pfam PF01613 Flavin reductase like domain 13 157 1.1E-29 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS30605 c8b4b6cfc0fdaebfccd07535208a6208 158 SUPERFAMILY SSF50475 8 157 3.83E-38 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS30605 c8b4b6cfc0fdaebfccd07535208a6208 158 Gene3D G3DSA:2.30.110.10 3 158 8.3E-35 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS30605 c8b4b6cfc0fdaebfccd07535208a6208 158 SMART SM00903 12 156 2.5E-38 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 SUPERFAMILY SSF50370 419 546 5.9E-41 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 Gene3D G3DSA:3.20.20.70 32 327 4.1E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 Gene3D G3DSA:2.80.10.50 471 507 5.4E-13 T 28-03-2018 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 Pfam PF00652 Ricin-type beta-trefoil lectin domain 423 545 1.1E-30 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 Gene3D G3DSA:4.10.1090.10 401 470 7.8E-15 T 28-03-2018 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 PRINTS PR00740 Glycosyl hydrolase family 27 signature 73 88 2.7E-47 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 PRINTS PR00740 Glycosyl hydrolase family 27 signature 37 56 2.7E-47 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 PRINTS PR00740 Glycosyl hydrolase family 27 signature 261 280 2.7E-47 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 PRINTS PR00740 Glycosyl hydrolase family 27 signature 282 303 2.7E-47 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 PRINTS PR00740 Glycosyl hydrolase family 27 signature 184 202 2.7E-47 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 PRINTS PR00740 Glycosyl hydrolase family 27 signature 155 172 2.7E-47 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 SUPERFAMILY SSF51011 319 413 6.48E-17 T 28-03-2018 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 Gene3D G3DSA:2.80.10.50 508 548 1.4E-14 T 28-03-2018 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 SMART SM00458 420 548 5.8E-27 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 SUPERFAMILY SSF51445 36 327 1.05E-83 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 Pfam PF16499 Alpha galactosidase A 42 326 3.9E-73 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 Gene3D G3DSA:2.60.40.1180 331 400 6.6E-22 T 28-03-2018 CNX65_RS15735 0032d7812027ab9e6855a12181728ecf 548 ProSitePatterns PS00512 Alpha-galactosidase signature. 78 94 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 122 134 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 Gene3D G3DSA:3.30.420.40 1 231 3.9E-65 T 28-03-2018 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 211 3.0E-42 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 330 351 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 SUPERFAMILY SSF53067 230 451 4.39E-44 T 28-03-2018 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 236 419 3.9E-24 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 Gene3D G3DSA:3.30.420.40 232 455 1.4E-50 T 28-03-2018 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 SUPERFAMILY SSF53067 4 228 2.27E-48 T 28-03-2018 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 TIGRFAM TIGR01312 XylB: xylulokinase 6 428 1.5E-115 T 28-03-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 CNX65_RS08960 35a394eb25f806121d0ab06ceaea429f 460 PIRSF PIRSF000538 1 453 1.3E-74 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 Gene3D G3DSA:3.40.190.10 92 162 4.5E-20 T 28-03-2018 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 SUPERFAMILY SSF55021 175 271 1.23E-25 T 28-03-2018 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 219 226 - T 28-03-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 PIRSF PIRSF001500 4 274 9.5E-57 T 28-03-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 Pfam PF00800 Prephenate dehydratase 8 179 5.2E-45 T 28-03-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 Pfam PF01842 ACT domain 192 256 1.6E-9 T 28-03-2018 IPR002912 ACT domain CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 Gene3D G3DSA:3.30.70.260 182 278 2.8E-29 T 28-03-2018 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 SUPERFAMILY SSF53850 7 186 4.96E-45 T 28-03-2018 CNX65_RS00505 7ba2a9bd4a1e3168ff54a81c7a692d4b 300 Gene3D G3DSA:3.40.190.10 3 91 1.2E-25 T 28-03-2018 CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 SMART SM00382 699 1044 8.4E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 SMART SM00382 63 317 8.4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 Gene3D G3DSA:3.40.50.300 662 1050 8.3E-21 T 28-03-2018 CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 Gene3D G3DSA:3.40.50.300 45 306 4.4E-6 T 28-03-2018 CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 Pfam PF01935 Domain of unknown function DUF87 696 744 8.4E-8 T 28-03-2018 IPR002789 Helicase HerA, central domain CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 SUPERFAMILY SSF52540 233 374 8.07E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 SUPERFAMILY SSF52540 62 120 8.07E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25290 bcfcfebf7dc75d870b01d98b59117ba8 1082 SUPERFAMILY SSF52540 659 1028 2.33E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF52151 553 658 4.45E-29 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF52151 720 819 4.45E-29 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Pfam PF00698 Acyl transferase domain 604 798 1.4E-16 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Gene3D G3DSA:3.40.366.10 554 837 6.6E-36 T 28-03-2018 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF55048 656 717 1.14E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Gene3D G3DSA:3.90.470.20 1338 1421 6.1E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 202 218 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF54637 1119 1188 5.35E-5 T 28-03-2018 IPR029069 HotDog domain CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SMART SM00825 Beta-ketoacyl synthase 7 465 1.6E-100 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Gene3D G3DSA:3.10.129.10 940 1050 0.0011 T 28-03-2018 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Gene3D G3DSA:3.40.47.10 2 301 1.6E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF53901 5 125 3.85E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF53901 184 411 3.85E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF53901 440 461 3.85E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 557 831 6.2E-13 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF56214 1231 1324 6.54E-9 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 297 415 1.2E-34 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Gene3D G3DSA:3.40.47.10 304 463 1.7E-52 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 1329 1405 9.3E-12 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 289 7.1E-63 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Pfam PF14765 Polyketide synthase dehydratase 978 1193 1.1E-17 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Gene3D G3DSA:3.10.129.10 1109 1188 3.0E-5 T 28-03-2018 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Gene3D G3DSA:3.90.470.20 1219 1337 3.2E-16 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 420 492 9.6E-10 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS12640 a6e7eb241a6805843967a27a3ae1596b 1438 SUPERFAMILY SSF56214 1328 1409 2.62E-14 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS27690 b3c1b9d117f0dcbc6a264556fd883bab 419 Gene3D G3DSA:3.60.21.10 191 418 8.6E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS27690 b3c1b9d117f0dcbc6a264556fd883bab 419 SUPERFAMILY SSF56300 193 415 7.99E-40 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS27690 b3c1b9d117f0dcbc6a264556fd883bab 419 Pfam PF00149 Calcineurin-like phosphoesterase 193 357 6.3E-13 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS25285 19177b8623402dc9d1d63892187596a1 200 Gene3D G3DSA:1.10.10.10 3 114 0.0021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 Pfam PF03129 Anticodon binding domain 329 416 1.6E-11 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 SUPERFAMILY SSF55681 7 313 8.23E-87 T 28-03-2018 CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 3 417 30.733 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 SUPERFAMILY SSF52954 326 418 7.1E-21 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 PIRSF PIRSF001549 2 419 1.6E-106 T 28-03-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 7 407 6.0E-134 T 28-03-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 Pfam PF13393 Histidyl-tRNA synthetase 10 309 8.5E-45 T 28-03-2018 CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 Gene3D G3DSA:3.30.930.10 2 320 1.7E-68 T 28-03-2018 CNX65_RS08490 20a26be3faa351577c631e5f8cee92d0 421 Gene3D G3DSA:3.40.50.800 323 420 5.1E-17 T 28-03-2018 IPR004154 Anticodon-binding CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 Pfam PF13492 GAF domain 225 311 2.1E-9 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 SMART SM00065 32 166 8.1E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 SMART SM00065 187 320 0.0092 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 Pfam PF01590 GAF domain 108 156 1.0E-4 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 Gene3D G3DSA:3.30.565.10 396 524 1.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 SUPERFAMILY SSF55781 34 182 1.61E-24 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 Pfam PF07730 Histidine kinase 328 390 7.1E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 Gene3D G3DSA:3.30.450.40 101 173 8.5E-17 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 SMART SM00387 430 524 3.4E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 SUPERFAMILY SSF55874 391 522 5.24E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 SUPERFAMILY SSF55781 152 311 6.76E-17 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 Gene3D G3DSA:3.30.450.40 12 100 8.9E-8 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS30005 c8f88efc674f457b0c41a280819bafb5 525 Gene3D G3DSA:3.30.450.40 174 323 1.6E-19 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS26050 c71a9b8a5188d7a83bd86992c3ddfccb 665 Hamap MF_00983 Probable primosomal protein N' [priA]. 27 664 19.972 T 28-03-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 CNX65_RS26050 c71a9b8a5188d7a83bd86992c3ddfccb 665 Gene3D G3DSA:3.40.50.300 170 271 0.0011 T 28-03-2018 CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 18 29 2.1E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 29 48 2.1E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 2 18 2.1E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 SUPERFAMILY SSF46785 3 71 6.06E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 Gene3D G3DSA:3.30.70.920 54 148 2.1E-18 T 28-03-2018 CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 Pfam PF13404 AsnC-type helix-turn-helix domain 3 42 5.2E-7 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 Pfam PF01037 Lrp/AsnC ligand binding domain 80 138 1.1E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 Gene3D G3DSA:1.10.10.10 2 52 1.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 SUPERFAMILY SSF54909 62 146 2.82E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS03515 b7450073591b437e7516104ae7be75c9 158 SMART SM00344 2 108 9.1E-13 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 Pfam PF00069 Protein kinase domain 12 264 2.0E-50 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 SUPERFAMILY SSF56112 5 301 1.34E-73 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 PIRSF PIRSF000654 18 273 2.7E-20 T 28-03-2018 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 PIRSF PIRSF000654 516 555 580.0 T 28-03-2018 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 SMART SM00220 12 270 2.5E-66 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 Gene3D G3DSA:3.30.200.20 2 99 1.1E-22 T 28-03-2018 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 Gene3D G3DSA:1.10.510.10 100 362 6.2E-50 T 28-03-2018 CNX65_RS31995 dbdddcd9b78d2d09e245adc0aa1c3592 558 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS24520 bfb2f248ebcbc1d4220b47b0e5a9afbc 378 Gene3D G3DSA:3.40.50.2000 1 201 2.9E-24 T 28-03-2018 CNX65_RS24520 bfb2f248ebcbc1d4220b47b0e5a9afbc 378 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 212 362 5.4E-33 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CNX65_RS24520 bfb2f248ebcbc1d4220b47b0e5a9afbc 378 Gene3D G3DSA:3.40.50.2000 202 362 5.7E-31 T 28-03-2018 CNX65_RS24520 bfb2f248ebcbc1d4220b47b0e5a9afbc 378 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 216 347 7.4E-6 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CNX65_RS24520 bfb2f248ebcbc1d4220b47b0e5a9afbc 378 SUPERFAMILY SSF53756 2 374 9.42E-62 T 28-03-2018 CNX65_RS23900 e667e1b800ed2bf95fa42119b49f834c 397 Gene3D G3DSA:1.10.630.10 1 394 2.0E-37 T 28-03-2018 CNX65_RS23900 e667e1b800ed2bf95fa42119b49f834c 397 PRINTS PR00359 B-class P450 signature 185 207 9.9E-17 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS23900 e667e1b800ed2bf95fa42119b49f834c 397 PRINTS PR00359 B-class P450 signature 134 150 9.9E-17 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS23900 e667e1b800ed2bf95fa42119b49f834c 397 PRINTS PR00359 B-class P450 signature 88 99 9.9E-17 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS23900 e667e1b800ed2bf95fa42119b49f834c 397 PRINTS PR00359 B-class P450 signature 328 337 9.9E-17 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS23900 e667e1b800ed2bf95fa42119b49f834c 397 PRINTS PR00359 B-class P450 signature 281 308 9.9E-17 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS23900 e667e1b800ed2bf95fa42119b49f834c 397 SUPERFAMILY SSF48264 7 392 5.76E-53 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS00135 734e9dc66a6402ba57cff5282696bc58 154 SUPERFAMILY SSF49879 57 153 2.3E-26 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CNX65_RS00135 734e9dc66a6402ba57cff5282696bc58 154 Gene3D G3DSA:2.60.200.20 52 154 2.0E-23 T 28-03-2018 CNX65_RS00135 734e9dc66a6402ba57cff5282696bc58 154 Pfam PF00498 FHA domain 83 146 5.3E-17 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CNX65_RS00135 734e9dc66a6402ba57cff5282696bc58 154 SMART SM00240 81 131 4.3E-13 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 Gene3D G3DSA:3.40.50.300 537 763 1.4E-45 T 28-03-2018 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 Gene3D G3DSA:3.10.28.10 414 466 1.2E-6 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 Pfam PF03796 DnaB-like helicase C terminal domain 537 760 8.9E-84 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 Pfam PF03796 DnaB-like helicase C terminal domain 187 254 6.0E-10 T 28-03-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 Gene3D G3DSA:1.10.860.10 1 153 2.0E-53 T 28-03-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 10 762 4.0E-156 T 28-03-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 Pfam PF00772 DnaB-like helicase N terminal domain 9 111 1.2E-33 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 Gene3D G3DSA:2.170.16.10 220 413 1.1E-12 T 28-03-2018 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 SUPERFAMILY SSF52540 186 218 9.11E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 SUPERFAMILY SSF52540 538 748 5.31E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 SUPERFAMILY SSF55608 405 464 1.02E-8 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 SUPERFAMILY SSF51294 486 537 2.55E-5 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 SUPERFAMILY SSF51294 220 340 2.55E-5 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS34800 8582a7ca837647f7d9a7b5dfda43d54b 764 SUPERFAMILY SSF48024 8 119 1.06E-36 T 28-03-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 SMART SM00636 168 521 8.7E-112 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 ProSitePatterns PS01095 Chitinases family 18 active site. 302 310 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 Gene3D G3DSA:3.20.20.80 155 536 2.7E-81 T 28-03-2018 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 Pfam PF00553 Cellulose binding domain 35 133 2.0E-27 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 SUPERFAMILY SSF49384 30 134 4.26E-29 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 Pfam PF00704 Glycosyl hydrolases family 18 171 521 1.4E-74 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 SMART SM00637 34 133 2.4E-39 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 SUPERFAMILY SSF51445 163 431 3.78E-80 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 SUPERFAMILY SSF51445 491 535 3.78E-80 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 SUPERFAMILY SSF54556 433 492 6.57E-14 T 28-03-2018 IPR029070 Chitinase insertion domain CNX65_RS30550 d5fcd67f5b1c6f37f39742caf8f62f9c 536 Gene3D G3DSA:2.60.40.290 25 133 1.1E-30 T 28-03-2018 CNX65_RS07135 1b6901e5ea39acdef62cc29a33eb4dda 300 Pfam PF01715 IPP transferase 37 279 5.9E-72 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CNX65_RS07135 1b6901e5ea39acdef62cc29a33eb4dda 300 Gene3D G3DSA:3.40.50.300 2 182 1.8E-59 T 28-03-2018 CNX65_RS07135 1b6901e5ea39acdef62cc29a33eb4dda 300 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 5 286 3.1E-73 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CNX65_RS07135 1b6901e5ea39acdef62cc29a33eb4dda 300 SUPERFAMILY SSF52540 5 145 1.78E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07135 1b6901e5ea39acdef62cc29a33eb4dda 300 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 4 296 27.246 T 28-03-2018 IPR018022 tRNA dimethylallyltransferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 CNX65_RS07135 1b6901e5ea39acdef62cc29a33eb4dda 300 Gene3D G3DSA:1.10.287.890 195 276 1.1E-19 T 28-03-2018 CNX65_RS13510 bae98f4ad8346678e08b30b2cccef29b 435 Gene3D G3DSA:1.20.91.10 262 346 4.9E-17 T 28-03-2018 CNX65_RS13510 bae98f4ad8346678e08b30b2cccef29b 435 Pfam PF00999 Sodium/hydrogen exchanger family 24 415 6.9E-50 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Gene3D G3DSA:2.60.120.260 84 227 3.4E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Gene3D G3DSA:2.60.120.260 1144 1299 1.7E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Gene3D G3DSA:2.70.98.10 400 698 9.4E-77 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Gene3D G3DSA:1.20.1050.60 737 831 5.6E-30 T 28-03-2018 CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 SUPERFAMILY SSF48208 639 1119 4.25E-18 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Gene3D G3DSA:3.30.2080.10 999 1143 1.6E-61 T 28-03-2018 CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Gene3D G3DSA:1.20.1610.10 832 998 2.4E-51 T 28-03-2018 CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Pfam PF00754 F5/8 type C domain 100 216 6.2E-12 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 SUPERFAMILY SSF49785 98 211 4.68E-15 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Gene3D G3DSA:2.60.120.260 228 391 3.3E-4 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 400 1139 8.1E-152 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CNX65_RS30325 07dc37f280580782d7cfecc192f3f3c9 1426 Pfam PF07971 Glycosyl hydrolase family 92 612 1136 2.9E-154 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 Gene3D G3DSA:3.30.70.890 171 300 3.9E-32 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 9 298 30.884 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 10 280 7.4E-53 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 PIRSF PIRSF010376 8 306 6.8E-79 T 28-03-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00710+2.7.1.14|KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 Pfam PF00288 GHMP kinases N terminal domain 96 154 6.4E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 Pfam PF08544 GHMP kinases C terminal 213 285 6.1E-9 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 SUPERFAMILY SSF55060 173 293 7.19E-24 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 SUPERFAMILY SSF54211 8 167 9.11E-44 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS03205 87cf024a584586c4d54ad6b5049a62a1 321 Gene3D G3DSA:3.30.230.10 9 169 3.1E-48 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 Gene3D G3DSA:3.40.640.10 188 303 3.9E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 15 407 7.2E-141 T 28-03-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 Gene3D G3DSA:3.90.1150.10 304 409 5.3E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 Pfam PF00202 Aminotransferase class-III 26 407 4.3E-110 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 PIRSF PIRSF000521 184 409 1.1E-25 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 PIRSF PIRSF000521 3 173 3.9E-7 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 232 269 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 Gene3D G3DSA:3.90.1150.10 2 187 9.8E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS07865 61cfdfd49be0e25d2b3baff2bb874bff 409 SUPERFAMILY SSF53383 13 408 2.18E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS25315 09d90c59a2a65184bcdd16a2449b6f9c 304 SUPERFAMILY SSF53067 8 127 6.47E-23 T 28-03-2018 CNX65_RS25315 09d90c59a2a65184bcdd16a2449b6f9c 304 Gene3D G3DSA:3.30.420.150 119 290 3.5E-29 T 28-03-2018 CNX65_RS25315 09d90c59a2a65184bcdd16a2449b6f9c 304 Gene3D G3DSA:3.30.420.40 2 118 6.6E-28 T 28-03-2018 CNX65_RS25315 09d90c59a2a65184bcdd16a2449b6f9c 304 Pfam PF02541 Ppx/GppA phosphatase family 24 290 1.4E-44 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CNX65_RS25315 09d90c59a2a65184bcdd16a2449b6f9c 304 SUPERFAMILY SSF53067 131 291 1.46E-21 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Pfam PF12826 Helix-hairpin-helix motif 505 548 7.8E-7 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 13 653 1.1E-163 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Gene3D G3DSA:3.30.1490.70 223 304 1.9E-12 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SUPERFAMILY SSF47781 388 565 1.7E-40 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Gene3D G3DSA:3.30.470.30 109 222 4.1E-32 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Gene3D G3DSA:2.40.50.140 305 373 7.3E-27 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 105 134 - T 28-03-2018 IPR018239 NAD-dependent DNA ligase, active site CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SUPERFAMILY SSF56091 2 301 5.04E-70 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 PIRSF PIRSF001604 1 665 1.0E-188 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Hamap MF_01588 DNA ligase [ligA]. 1 660 46.608 T 28-03-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 2 301 4.4E-63 T 28-03-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Gene3D G3DSA:1.10.150.20 486 539 8.1E-11 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SUPERFAMILY SSF52113 579 658 1.57E-7 T 28-03-2018 IPR001357 BRCT domain CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 305 376 1.3E-25 T 28-03-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SMART SM00292 579 663 0.0082 T 28-03-2018 IPR001357 BRCT domain CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Gene3D G3DSA:3.40.50.10190 540 660 1.5E-9 T 28-03-2018 IPR001357 BRCT domain CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SUPERFAMILY SSF50249 300 375 7.54E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SMART SM00278 463 482 8.9 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SMART SM00278 528 547 0.84 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Gene3D G3DSA:1.10.150.20 415 485 1.4E-19 T 28-03-2018 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 SMART SM00532 2 431 1.5E-124 T 28-03-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 CNX65_RS14920 81f0e157bd93b3578bdd33135bf4e815 666 Gene3D G3DSA:1.10.287.610 1 65 1.1E-11 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF49478 1041 1105 8.24E-10 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 1356 1394 5.49E-5 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 1580 1657 4.05E-14 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 504 539 6.0E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF13620 Carboxypeptidase regulatory-like domain 1041 1095 5.6E-9 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF13620 Carboxypeptidase regulatory-like domain 829 897 1.4E-7 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.1120 829 923 6.0E-13 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 490 598 2.0E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.1120 1253 1352 1.9E-11 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 ProSitePatterns PS00018 EF-hand calcium-binding domain. 1590 1602 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 580 674 6.8E-9 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.1120 1036 1120 4.1E-11 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 689 796 4.05E-15 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF17210 SdrD B-like domain 715 795 1.1E-15 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF17210 SdrD B-like domain 599 687 2.0E-7 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF17210 SdrD B-like domain 1680 1793 7.5E-33 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF17210 SdrD B-like domain 1143 1226 6.7E-13 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF17210 SdrD B-like domain 927 1006 6.6E-15 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF17210 SdrD B-like domain 1583 1662 4.5E-13 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF17210 SdrD B-like domain 1266 1334 2.8E-8 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 1801 1936 2.3E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 392 489 0.087 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 1230 1325 7.72E-11 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF49464 829 915 7.45E-11 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 1357 1562 3.5E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 924 1030 2.7E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 1138 1250 6.6E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 710 813 1.1E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 599 705 5.1E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 1676 1800 4.1E-26 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Gene3D G3DSA:2.60.40.10 1579 1675 1.5E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 1664 1753 1.11E-23 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 920 1000 2.09E-14 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 1133 1225 4.32E-10 T 28-03-2018 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 Pfam PF01345 Domain of unknown function DUF11 502 575 3.8E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS02900 f5ad7d435cc64df3734cb510109f15a1 2007 SUPERFAMILY SSF117074 1481 1545 7.45E-6 T 28-03-2018 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 SUPERFAMILY SSF52172 2 129 9.39E-35 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 SMART SM00448 2 112 2.0E-34 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 SMART SM00421 134 191 4.0E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 Pfam PF00072 Response regulator receiver domain 4 113 7.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 SUPERFAMILY SSF46894 125 197 7.82E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 190 2.5E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 Gene3D G3DSA:3.40.50.2300 1 123 7.3E-41 T 28-03-2018 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 Gene3D G3DSA:1.10.10.10 124 199 3.7E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02610 199944b9181d9ddbd75a6da918121545 199 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 Pfam PF01842 ACT domain 4 69 3.5E-18 T 28-03-2018 IPR002912 ACT domain CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 Gene3D G3DSA:3.30.70.1150 89 161 4.0E-28 T 28-03-2018 CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 4 76 1.0E-31 T 28-03-2018 CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 Gene3D G3DSA:3.30.70.260 1 88 2.8E-26 T 28-03-2018 CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 SUPERFAMILY SSF55021 82 161 1.37E-24 T 28-03-2018 CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 Pfam PF10369 Small subunit of acetolactate synthase 85 158 5.4E-27 T 28-03-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 3 158 4.4E-62 T 28-03-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 CNX65_RS29610 bcd08afd57ad35bd2202fcd2564dd2b3 168 SUPERFAMILY SSF55021 2 75 6.55E-24 T 28-03-2018 CNX65_RS02245 0f18bda05849351a57d67f5c7456fb89 110 PRINTS PR00308 Type I antifreeze protein signature 30 44 1.4E-12 T 28-03-2018 IPR000104 Antifreeze protein, type I GO:0050825 CNX65_RS02245 0f18bda05849351a57d67f5c7456fb89 110 PRINTS PR00308 Type I antifreeze protein signature 44 55 1.4E-12 T 28-03-2018 IPR000104 Antifreeze protein, type I GO:0050825 CNX65_RS02245 0f18bda05849351a57d67f5c7456fb89 110 PRINTS PR00308 Type I antifreeze protein signature 55 64 1.4E-12 T 28-03-2018 IPR000104 Antifreeze protein, type I GO:0050825 CNX65_RS34165 aed7c462177e25071ca419934b3c1991 359 Pfam PF13515 Fusaric acid resistance protein-like 34 153 4.8E-13 T 28-03-2018 CNX65_RS13210 d12a83262e6f41ad8ccf34b1c9ee3304 338 Gene3D G3DSA:3.40.50.720 1 211 5.7E-33 T 28-03-2018 CNX65_RS13210 d12a83262e6f41ad8ccf34b1c9ee3304 338 Gene3D G3DSA:3.90.25.10 212 327 1.8E-7 T 28-03-2018 CNX65_RS13210 d12a83262e6f41ad8ccf34b1c9ee3304 338 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 224 1.0E-21 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS13210 d12a83262e6f41ad8ccf34b1c9ee3304 338 SUPERFAMILY SSF51735 286 319 9.05E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13210 d12a83262e6f41ad8ccf34b1c9ee3304 338 SUPERFAMILY SSF51735 1 255 9.05E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13520 9dbd45c167ebc525f9847a1e40fa983f 435 Gene3D G3DSA:1.20.1250.20 8 218 7.6E-23 T 28-03-2018 CNX65_RS13520 9dbd45c167ebc525f9847a1e40fa983f 435 Pfam PF07690 Major Facilitator Superfamily 42 344 6.3E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS13520 9dbd45c167ebc525f9847a1e40fa983f 435 Gene3D G3DSA:1.20.1250.20 223 418 4.6E-19 T 28-03-2018 CNX65_RS13520 9dbd45c167ebc525f9847a1e40fa983f 435 SUPERFAMILY SSF103473 29 405 1.27E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01735 99e980427a68df63f7a832c8fa286cfc 256 SUPERFAMILY SSF52467 2 255 6.07E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS01735 99e980427a68df63f7a832c8fa286cfc 256 Pfam PF02146 Sir2 family 13 170 2.2E-18 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CNX65_RS01735 99e980427a68df63f7a832c8fa286cfc 256 Gene3D G3DSA:3.40.50.1220 1 256 1.8E-27 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS17385 2e704bb3e32838583bebd04725ef70a9 200 Gene3D G3DSA:1.10.10.60 1 55 3.3E-13 T 28-03-2018 CNX65_RS17385 2e704bb3e32838583bebd04725ef70a9 200 Pfam PF16859 Bacterial transcriptional repressor C-terminal 72 182 3.5E-28 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS17385 2e704bb3e32838583bebd04725ef70a9 200 SUPERFAMILY SSF46689 3 62 1.28E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS17385 2e704bb3e32838583bebd04725ef70a9 200 Gene3D G3DSA:1.10.357.10 56 198 6.7E-18 T 28-03-2018 CNX65_RS17385 2e704bb3e32838583bebd04725ef70a9 200 SUPERFAMILY SSF48498 72 186 5.13E-22 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS17385 2e704bb3e32838583bebd04725ef70a9 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 59 3.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS04725 6ef01ead85ef7b940f3bea9182bdee62 468 SUPERFAMILY SSF56112 137 287 3.86E-11 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS04725 6ef01ead85ef7b940f3bea9182bdee62 468 Gene3D G3DSA:1.10.510.10 112 289 1.0E-8 T 28-03-2018 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 Pfam PF03704 Bacterial transcriptional activator domain 101 242 3.2E-32 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 Pfam PF00486 Transcriptional regulatory protein, C terminal 24 96 1.1E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 Gene3D G3DSA:1.25.40.10 575 1021 0.002 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 SUPERFAMILY SSF52540 252 475 9.42E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 Gene3D G3DSA:1.10.10.10 1 98 3.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 Gene3D G3DSA:1.25.40.10 99 265 1.5E-22 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 SMART SM01043 101 242 7.0E-41 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 SUPERFAMILY SSF46894 2 96 5.67E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 SMART SM00862 18 96 3.6E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 Gene3D G3DSA:3.40.50.300 266 408 3.4E-13 T 28-03-2018 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 SMART SM00382 285 429 1.4E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 SUPERFAMILY SSF48452 100 264 2.17E-28 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30365 06689ff59111af766af25b3c9b478a3f 1021 Pfam PF13191 AAA ATPase domain 262 391 4.4E-15 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF00698 Acyl transferase domain 555 863 1.2E-81 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:1.10.1200.10 1621 1731 4.9E-22 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF14765 Polyketide synthase dehydratase 910 1180 1.7E-64 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF53901 31 406 1.03E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:3.40.47.10 26 296 2.7E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1677 1692 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF55048 677 739 2.75E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:3.30.70.250 689 728 6.6E-15 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SMART SM00825 Beta-ketoacyl synthase 36 460 6.2E-210 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 1.4E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:3.40.366.10 729 852 1.5E-22 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF51735 1183 1358 9.84E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SMART SM01294 1651 1718 1.7E-4 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF52151 554 679 1.39E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF52151 740 833 1.39E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF101173 3 32 6.02E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SMART SM00826 910 1070 1.5E-80 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF47336 1643 1729 6.41E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:3.40.50.720 1364 1608 8.6E-47 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 557 844 2.0E-108 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF00550 Phosphopantetheine attachment site 1652 1717 7.4E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SUPERFAMILY SSF51735 1370 1616 1.29E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF08990 Erythronolide synthase docking 2 27 1.1E-10 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 493 1.9E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF08659 KR domain 1370 1546 7.1E-56 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:3.10.129.10 915 1037 3.7E-8 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SMART SM00823 Phosphopantetheine attachment site 1650 1722 1.2E-32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:3.40.366.10 553 688 5.1E-40 T 28-03-2018 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 284 2.0E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 Gene3D G3DSA:3.40.47.10 299 458 2.6E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15340 7af71f9915368c9da5756c483d38df0f 1796 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1370 1548 6.8E-54 T 28-03-2018 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 SUPERFAMILY SSF49265 223 315 6.37E-18 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 SMART SM00637 325 425 5.4E-43 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 Gene3D G3DSA:2.70.50.50 32 217 8.1E-53 T 28-03-2018 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 Gene3D G3DSA:2.60.40.10 225 319 2.3E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 390 403 - T 28-03-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 SUPERFAMILY SSF81296 32 217 8.68E-43 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 SMART SM00060 227 303 1.3E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 Pfam PF00041 Fibronectin type III domain 229 307 3.5E-10 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 SUPERFAMILY SSF49384 320 425 1.81E-32 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 32 214 2.1E-39 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 Gene3D G3DSA:2.60.40.290 320 425 2.9E-32 T 28-03-2018 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 PRINTS PR00014 Fibronectin type III repeat signature 290 304 3.8E-5 T 28-03-2018 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 PRINTS PR00014 Fibronectin type III repeat signature 272 290 3.8E-5 T 28-03-2018 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 PRINTS PR00014 Fibronectin type III repeat signature 252 262 3.8E-5 T 28-03-2018 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 PRINTS PR00014 Fibronectin type III repeat signature 240 249 3.8E-5 T 28-03-2018 CNX65_RS09090 14d287c86515ea16441531dcd7e1b543 428 Pfam PF00553 Cellulose binding domain 325 425 2.7E-30 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS03750 0bb3a71bf999b9662969171a5ab221cb 566 SUPERFAMILY SSF53850 49 550 8.32E-60 T 28-03-2018 CNX65_RS03750 0bb3a71bf999b9662969171a5ab221cb 566 Gene3D G3DSA:3.90.76.10 57 172 1.5E-13 T 28-03-2018 CNX65_RS03750 0bb3a71bf999b9662969171a5ab221cb 566 Gene3D G3DSA:3.10.105.10 310 532 7.5E-34 T 28-03-2018 CNX65_RS03750 0bb3a71bf999b9662969171a5ab221cb 566 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 111 427 4.3E-35 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS03750 0bb3a71bf999b9662969171a5ab221cb 566 Gene3D G3DSA:3.40.190.10 173 309 8.3E-22 T 28-03-2018 CNX65_RS31570 fc5687c39fe6fbd2721a618d6a43f86e 277 Gene3D G3DSA:1.10.3100.10 8 154 1.1E-12 T 28-03-2018 IPR027910 YdiL-like domain CNX65_RS31570 fc5687c39fe6fbd2721a618d6a43f86e 277 Pfam PF13560 Helix-turn-helix domain 14 74 1.9E-12 T 28-03-2018 CNX65_RS31570 fc5687c39fe6fbd2721a618d6a43f86e 277 SUPERFAMILY SSF47413 12 68 1.42E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS31570 fc5687c39fe6fbd2721a618d6a43f86e 277 SMART SM00530 16 70 4.0E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 Gene3D G3DSA:3.40.50.1220 197 358 2.0E-40 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 Gene3D G3DSA:3.40.50.970 359 564 2.3E-33 T 28-03-2018 CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 SUPERFAMILY SSF52467 162 357 1.18E-38 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 SUPERFAMILY SSF52518 7 187 1.09E-49 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 Gene3D G3DSA:3.40.50.970 2 196 5.6E-49 T 28-03-2018 CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 199 336 3.4E-30 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 SUPERFAMILY SSF52518 377 563 1.09E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 10 178 1.7E-48 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CNX65_RS14360 0c2efc0cc986f3ef66a1a39eba210030 574 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 400 546 5.3E-30 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 200 327 2.7E-31 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 SMART SM00086 133 175 6.0E-4 T 28-03-2018 IPR001610 PAC motif CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 SUPERFAMILY SSF55785 76 176 5.76E-14 T 28-03-2018 IPR000014 PAS domain CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 SMART SM00283 146 344 1.5E-7 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 SUPERFAMILY SSF58104 178 334 6.8E-46 T 28-03-2018 CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 Gene3D G3DSA:1.10.287.950 178 338 4.1E-38 T 28-03-2018 CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 Gene3D G3DSA:3.30.450.20 25 177 7.7E-19 T 28-03-2018 CNX65_RS09775 39b0a4cae65218c975b7acc6a944dd65 344 Pfam PF08447 PAS fold 79 168 1.7E-20 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 CNX65_RS12645 b790999952d2b65d42b9aabc76053448 104 Gene3D G3DSA:1.10.1200.10 15 102 7.9E-13 T 28-03-2018 CNX65_RS12645 b790999952d2b65d42b9aabc76053448 104 Pfam PF00550 Phosphopantetheine attachment site 31 80 4.3E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS12645 b790999952d2b65d42b9aabc76053448 104 SUPERFAMILY SSF47336 25 102 1.44E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS10020 b00683cf2661bf358b8ea513d901229d 471 Gene3D G3DSA:1.10.260.40 1 72 8.7E-18 T 28-03-2018 CNX65_RS10020 b00683cf2661bf358b8ea513d901229d 471 SUPERFAMILY SSF47413 3 67 2.39E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS10020 b00683cf2661bf358b8ea513d901229d 471 Pfam PF06114 IrrE N-terminal-like domain 179 306 2.6E-18 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CNX65_RS10020 b00683cf2661bf358b8ea513d901229d 471 Pfam PF09856 Predicted transcriptional regulator (DUF2083) 307 463 4.1E-68 T 28-03-2018 IPR018653 Domain of unknown function DUF2083,transcriptional regulator CNX65_RS10020 b00683cf2661bf358b8ea513d901229d 471 PIRSF PIRSF019251 1 467 9.0E-186 T 28-03-2018 IPR026281 HTH-type transcriptional regulator RamB GO:0006355 CNX65_RS10020 b00683cf2661bf358b8ea513d901229d 471 SMART SM00530 9 64 1.1E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS10020 b00683cf2661bf358b8ea513d901229d 471 Pfam PF13560 Helix-turn-helix domain 7 60 1.6E-13 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 SUPERFAMILY SSF52777 23 224 3.89E-45 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 Gene3D G3DSA:3.30.559.10 21 230 4.4E-41 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 SMART SM00823 Phosphopantetheine attachment site 1021 1091 0.0063 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 Gene3D G3DSA:1.10.1200.10 1016 1104 3.0E-17 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 Gene3D G3DSA:3.40.50.980 478 823 4.0E-9 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 SUPERFAMILY SSF47336 1016 1088 3.4E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 Pfam PF00550 Phosphopantetheine attachment site 1039 1087 1.1E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 SUPERFAMILY SSF56801 475 596 6.72E-24 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 SUPERFAMILY SSF56801 697 1002 6.72E-24 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1046 1061 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 Pfam PF00668 Condensation domain 24 442 4.9E-84 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 SUPERFAMILY SSF52777 213 456 2.67E-58 T 28-03-2018 CNX65_RS18330 965a5bc212cd25dbc2677e5bc9c123f5 1125 Gene3D G3DSA:3.30.300.30 904 1008 1.8E-12 T 28-03-2018 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 Pfam PF07687 Peptidase dimerisation domain 204 334 3.4E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 Pfam PF01546 Peptidase family M20/M25/M40 87 442 9.2E-40 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 SUPERFAMILY SSF53187 9 207 4.57E-55 T 28-03-2018 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 SUPERFAMILY SSF53187 353 442 4.57E-55 T 28-03-2018 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 86 95 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 Gene3D G3DSA:3.40.630.10 7 210 1.1E-43 T 28-03-2018 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 SUPERFAMILY SSF55031 207 249 6.86E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 SUPERFAMILY SSF55031 293 328 6.86E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 Gene3D G3DSA:3.30.70.360 211 346 4.3E-23 T 28-03-2018 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 PIRSF PIRSF036696 288 442 1.0E-7 T 28-03-2018 CNX65_RS24110 9bed88ca96ee80d5283c64d382491090 443 PIRSF PIRSF036696 8 250 4.9E-30 T 28-03-2018 CNX65_RS18260 c62575c9eedb12e94637389ad1520cd7 306 SUPERFAMILY SSF51735 6 303 1.11E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18260 c62575c9eedb12e94637389ad1520cd7 306 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 213 2.0E-8 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS18260 c62575c9eedb12e94637389ad1520cd7 306 Gene3D G3DSA:3.40.50.720 5 305 9.8E-28 T 28-03-2018 CNX65_RS11165 df31f175ea6aee10ea59b5e9bb97f699 444 Gene3D G3DSA:1.10.287.1060 31 119 9.8E-7 T 28-03-2018 CNX65_RS11165 df31f175ea6aee10ea59b5e9bb97f699 444 SUPERFAMILY SSF140459 33 176 2.04E-9 T 28-03-2018 CNX65_RS11165 df31f175ea6aee10ea59b5e9bb97f699 444 PRINTS PR01228 Eggshell protein signature 282 293 3.5E-5 T 28-03-2018 CNX65_RS11165 df31f175ea6aee10ea59b5e9bb97f699 444 PRINTS PR01228 Eggshell protein signature 352 367 3.5E-5 T 28-03-2018 CNX65_RS11165 df31f175ea6aee10ea59b5e9bb97f699 444 PRINTS PR01228 Eggshell protein signature 377 387 3.5E-5 T 28-03-2018 CNX65_RS11165 df31f175ea6aee10ea59b5e9bb97f699 444 PRINTS PR01228 Eggshell protein signature 404 422 3.5E-5 T 28-03-2018 CNX65_RS11165 df31f175ea6aee10ea59b5e9bb97f699 444 Pfam PF00823 PPE family 35 116 6.4E-8 T 28-03-2018 IPR000030 PPE family CNX65_RS14485 0e2c52a0df5af237c89da159d33ffec0 303 Gene3D G3DSA:3.40.50.1980 16 142 8.5E-13 T 28-03-2018 CNX65_RS14485 0e2c52a0df5af237c89da159d33ffec0 303 Pfam PF01497 Periplasmic binding protein 36 274 2.3E-24 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS14485 0e2c52a0df5af237c89da159d33ffec0 303 SUPERFAMILY SSF53807 65 298 1.88E-33 T 28-03-2018 CNX65_RS14485 0e2c52a0df5af237c89da159d33ffec0 303 Gene3D G3DSA:3.40.50.1980 143 303 2.0E-27 T 28-03-2018 CNX65_RS12180 2bbd8d869da9edd30fb18732ac8d33c6 169 SUPERFAMILY SSF46785 28 156 4.12E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12180 2bbd8d869da9edd30fb18732ac8d33c6 169 SMART SM00347 46 145 0.0066 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12180 2bbd8d869da9edd30fb18732ac8d33c6 169 Gene3D G3DSA:1.10.10.10 19 161 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12180 2bbd8d869da9edd30fb18732ac8d33c6 169 Pfam PF12802 MarR family 51 110 3.5E-10 T 28-03-2018 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 Pfam PF14016 Protein of unknown function (DUF4232) 440 568 6.8E-27 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 124 136 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 Pfam PF00069 Protein kinase domain 7 251 4.6E-41 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 Gene3D G3DSA:1.10.510.10 89 367 1.1E-38 T 28-03-2018 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 SMART SM00220 6 260 8.9E-50 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 12 34 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 Gene3D G3DSA:3.30.200.20 1 88 7.9E-17 T 28-03-2018 CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 SUPERFAMILY SSF56112 286 315 7.69E-64 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS23310 4d25ee84652f113cc8eb45637e705c7b 573 SUPERFAMILY SSF56112 3 257 7.69E-64 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS14940 c53b568c9b8e6313f94a37126aa02c72 548 SUPERFAMILY SSF53474 229 283 7.34E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14940 c53b568c9b8e6313f94a37126aa02c72 548 SUPERFAMILY SSF53474 395 533 7.34E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14940 c53b568c9b8e6313f94a37126aa02c72 548 SUPERFAMILY SSF53474 142 197 7.34E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14940 c53b568c9b8e6313f94a37126aa02c72 548 Gene3D G3DSA:3.40.50.1820 114 539 2.2E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14940 c53b568c9b8e6313f94a37126aa02c72 548 Pfam PF00561 alpha/beta hydrolase fold 147 531 1.5E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS27550 a5bc2712c19581c7df0edbd6976e1698 136 Gene3D G3DSA:3.10.129.10 6 135 4.8E-28 T 28-03-2018 CNX65_RS27550 a5bc2712c19581c7df0edbd6976e1698 136 SUPERFAMILY SSF54637 1 132 7.67E-30 T 28-03-2018 IPR029069 HotDog domain CNX65_RS27550 a5bc2712c19581c7df0edbd6976e1698 136 Pfam PF03061 Thioesterase superfamily 48 124 4.7E-17 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CNX65_RS27550 a5bc2712c19581c7df0edbd6976e1698 136 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 19 131 2.8E-30 T 28-03-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 CNX65_RS07935 a0b3390fded6811e3ca2105b752006e3 483 Pfam PF13531 Bacterial extracellular solute-binding protein 92 266 1.2E-18 T 28-03-2018 CNX65_RS07935 a0b3390fded6811e3ca2105b752006e3 483 Gene3D G3DSA:3.40.50.410 311 480 6.5E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS07935 a0b3390fded6811e3ca2105b752006e3 483 Gene3D G3DSA:3.40.190.10 176 282 8.1E-7 T 28-03-2018 CNX65_RS07935 a0b3390fded6811e3ca2105b752006e3 483 SMART SM00327 315 481 1.1E-8 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS07935 a0b3390fded6811e3ca2105b752006e3 483 SUPERFAMILY SSF53850 88 288 3.03E-13 T 28-03-2018 CNX65_RS07935 a0b3390fded6811e3ca2105b752006e3 483 SUPERFAMILY SSF53300 318 471 4.01E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS07935 a0b3390fded6811e3ca2105b752006e3 483 Pfam PF13519 von Willebrand factor type A domain 318 422 5.0E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 SUPERFAMILY SSF50129 9 140 1.27E-35 T 28-03-2018 IPR011032 GroES-like CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 Gene3D G3DSA:3.90.180.10 1 133 2.2E-33 T 28-03-2018 CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 Gene3D G3DSA:3.40.50.720 134 307 1.9E-28 T 28-03-2018 CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 SMART SM00829 11 321 6.3E-19 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 SUPERFAMILY SSF51735 110 266 6.61E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 Pfam PF00107 Zinc-binding dehydrogenase 150 253 3.9E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 87 1.0E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS25755 cc3b7961a4a984926f4d967ab4f35f7d 323 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 139 160 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS24610 8770b7d53dcde315b6af9268b0614af1 305 SUPERFAMILY SSF53474 27 298 9.92E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24610 8770b7d53dcde315b6af9268b0614af1 305 Pfam PF12697 Alpha/beta hydrolase family 44 295 5.9E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS24610 8770b7d53dcde315b6af9268b0614af1 305 Gene3D G3DSA:3.40.50.1820 15 299 5.2E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS33805 add14d4e437cb5f3eab7eb70665f481d 266 Gene3D G3DSA:3.20.20.70 1 264 4.6E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS33805 add14d4e437cb5f3eab7eb70665f481d 266 Pfam PF05853 beta-keto acid cleavage enzyme 2 259 2.0E-50 T 28-03-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247|KEGG: 00600+2.3.1.24 CNX65_RS23710 aa66a2e2b7ec1264c80d82987d1200af 489 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 173 213 1.7E-9 T 28-03-2018 IPR022435 Surface-anchored repeat, actinobacteria CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 Gene3D G3DSA:3.40.50.300 1162 1318 4.2E-5 T 28-03-2018 CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 Gene3D G3DSA:3.40.50.300 19 648 1.7E-4 T 28-03-2018 CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 SUPERFAMILY SSF52540 961 1001 1.24E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 SUPERFAMILY SSF52540 283 298 1.24E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 SUPERFAMILY SSF52540 1238 1311 1.24E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 SUPERFAMILY SSF52540 12 134 1.24E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 TIGRFAM TIGR02680 TIGR02680: TIGR02680 family protein 4 1356 1.3E-208 T 28-03-2018 IPR013496 Conserved hypothetical protein CHP02680 CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 Pfam PF13558 Putative exonuclease SbcCD, C subunit 1222 1309 2.3E-19 T 28-03-2018 CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 Gene3D G3DSA:1.20.120.330 755 929 0.005 T 28-03-2018 CNX65_RS04290 7569ebecffbd8a4309def8e17d9320bd 1363 Gene3D G3DSA:1.20.120.330 930 1158 5.5E-5 T 28-03-2018 CNX65_RS25885 fd3a211e8a7330ea83d2eab3a1b404eb 348 Hamap MF_00973 Gluconeogenesis factor. 1 314 30.701 T 28-03-2018 IPR010119 Gluconeogenesis factor CNX65_RS25885 fd3a211e8a7330ea83d2eab3a1b404eb 348 Gene3D G3DSA:3.40.50.10680 82 316 6.2E-53 T 28-03-2018 CNX65_RS25885 fd3a211e8a7330ea83d2eab3a1b404eb 348 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 4 275 3.3E-85 T 28-03-2018 IPR010119 Gluconeogenesis factor CNX65_RS25885 fd3a211e8a7330ea83d2eab3a1b404eb 348 SUPERFAMILY SSF142338 3 308 1.83E-82 T 28-03-2018 CNX65_RS25885 fd3a211e8a7330ea83d2eab3a1b404eb 348 Pfam PF01933 Uncharacterised protein family UPF0052 4 278 6.1E-73 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CNX65_RS08515 8771ea281769478ee2784390eea954f7 289 SUPERFAMILY SSF51294 9 130 1.49E-8 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS08515 8771ea281769478ee2784390eea954f7 289 SUPERFAMILY SSF51294 222 265 1.49E-8 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS08515 8771ea281769478ee2784390eea954f7 289 Gene3D G3DSA:2.170.16.10 4 117 6.4E-13 T 28-03-2018 CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 206 216 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 Pfam PF05922 Peptidase inhibitor I9 93 130 2.5E-5 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 Gene3D G3DSA:3.30.70.80 67 119 5.2E-14 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 Pfam PF00082 Subtilase family 173 392 3.6E-27 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 171 182 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 SUPERFAMILY SSF54897 66 131 4.48E-10 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 PRINTS PR00723 Subtilisin serine protease family (S8) signature 353 369 2.8E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 PRINTS PR00723 Subtilisin serine protease family (S8) signature 202 215 2.8E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 PRINTS PR00723 Subtilisin serine protease family (S8) signature 166 185 2.8E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 354 364 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 SUPERFAMILY SSF52743 142 396 2.23E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS17990 0e0fec06de6fcd7747bddca230bca1e5 412 Gene3D G3DSA:3.40.50.200 120 406 1.1E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 90 307 9.7E-16 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 SUPERFAMILY SSF51445 48 322 5.8E-30 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 Gene3D G3DSA:3.20.20.80 44 327 1.5E-26 T 28-03-2018 CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 SUPERFAMILY SSF50370 359 494 5.54E-40 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 Gene3D G3DSA:2.80.10.50 412 438 1.4E-15 T 28-03-2018 CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 443 496 3.0E-12 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 359 437 1.5E-19 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 Gene3D G3DSA:2.80.10.50 354 411 2.9E-12 T 28-03-2018 CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 Gene3D G3DSA:2.80.10.50 439 500 1.2E-21 T 28-03-2018 CNX65_RS23055 579bcfcd7199ad8a1a305d59d8a0e400 500 SMART SM00458 361 496 4.1E-12 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS03010 aa75b0ae3756b1782e818f50ced4c753 55 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 6 55 6.7E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03010 aa75b0ae3756b1782e818f50ced4c753 55 Pfam PF00471 Ribosomal protein L33 10 55 7.9E-16 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03010 aa75b0ae3756b1782e818f50ced4c753 55 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 7 55 14.008 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03010 aa75b0ae3756b1782e818f50ced4c753 55 ProSitePatterns PS00582 Ribosomal protein L33 signature. 23 42 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS03010 aa75b0ae3756b1782e818f50ced4c753 55 SUPERFAMILY SSF57829 5 55 1.16E-16 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 Gene3D G3DSA:1.10.8.50 120 267 1.3E-48 T 28-03-2018 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 Pfam PF06827 Zinc finger found in FPG and IleRS 238 266 2.4E-10 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 SMART SM01232 120 212 1.3E-31 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 Gene3D G3DSA:3.20.190.10 1 119 2.8E-18 T 28-03-2018 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 SUPERFAMILY SSF57716 219 265 4.18E-14 T 28-03-2018 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 120 205 8.8E-21 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 97 1.4E-6 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 SMART SM00898 2 106 1.7E-15 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 SUPERFAMILY SSF46946 119 204 2.21E-23 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 SUPERFAMILY SSF81624 2 121 1.83E-19 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS05710 fab83cd75b3759802eab5725e8b02336 267 ProSitePatterns PS01242 Zinc finger FPG-type signature. 241 265 - T 28-03-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SMART SM01058 490 591 9.0E-50 T 28-03-2018 IPR003711 CarD-like/TRCF domain CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 Pfam PF02559 CarD-like/TRCF domain 491 590 9.4E-33 T 28-03-2018 IPR003711 CarD-like/TRCF domain CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 Gene3D G3DSA:3.40.50.300 806 971 5.6E-23 T 28-03-2018 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SUPERFAMILY SSF52540 31 356 4.43E-71 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SUPERFAMILY SSF52540 541 798 1.03E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SUPERFAMILY SSF52540 797 1005 1.13E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SUPERFAMILY SSF141259 483 563 1.7E-19 T 28-03-2018 IPR003711 CarD-like/TRCF domain CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 154 1097 0.0 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 Pfam PF03461 TRCF domain 1025 1107 1.8E-23 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 Gene3D G3DSA:3.40.50.300 229 794 7.8E-35 T 28-03-2018 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 Pfam PF00271 Helicase conserved C-terminal domain 825 924 3.0E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 Pfam PF00270 DEAD/DEAH box helicase 623 781 2.7E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SUPERFAMILY SSF143517 1012 1172 7.85E-32 T 28-03-2018 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SMART SM00490 841 925 2.6E-16 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 39 1122 28.281 T 28-03-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SMART SM00487 615 805 4.0E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SMART SM00982 1024 1121 9.1E-36 T 28-03-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 CNX65_RS03300 21d28facb54c5d8ce1dfabf1ecd06b33 1181 SUPERFAMILY SSF52540 369 476 9.56E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23405 59b04f786ee9a8f4d3e76b780630c07e 181 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 13 98 2.4E-5 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS23405 59b04f786ee9a8f4d3e76b780630c07e 181 SUPERFAMILY SSF50475 10 150 6.48E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS23405 59b04f786ee9a8f4d3e76b780630c07e 181 Gene3D G3DSA:2.30.110.10 5 179 2.0E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS04115 5bf2f568a218333ad044d9528d7df088 272 SUPERFAMILY SSF56112 51 219 3.4E-12 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS04115 5bf2f568a218333ad044d9528d7df088 272 Gene3D G3DSA:1.10.510.10 134 243 5.8E-5 T 28-03-2018 CNX65_RS04115 5bf2f568a218333ad044d9528d7df088 272 TIGRFAM TIGR02569 TIGR02569_actnb: TIGR02569 family protein 13 268 1.2E-80 T 28-03-2018 IPR013402 Conserved hypothetical protein CHP02569 CNX65_RS00890 ba970245edf38b62492d2d10ff4015a1 205 Gene3D G3DSA:1.10.357.10 65 194 4.5E-19 T 28-03-2018 CNX65_RS00890 ba970245edf38b62492d2d10ff4015a1 205 SUPERFAMILY SSF48498 77 168 2.73E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS00890 ba970245edf38b62492d2d10ff4015a1 205 Pfam PF13305 WHG domain 84 165 6.8E-15 T 28-03-2018 IPR025996 WHG domain CNX65_RS00890 ba970245edf38b62492d2d10ff4015a1 205 Gene3D G3DSA:1.10.10.60 2 44 2.9E-6 T 28-03-2018 CNX65_RS00890 ba970245edf38b62492d2d10ff4015a1 205 Gene3D G3DSA:1.10.10.60 45 64 0.0015 T 28-03-2018 CNX65_RS00890 ba970245edf38b62492d2d10ff4015a1 205 SUPERFAMILY SSF46689 3 71 4.98E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Gene3D G3DSA:3.30.70.250 697 741 1.5E-15 T 28-03-2018 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF51735 1175 1398 2.14E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Pfam PF00698 Acyl transferase domain 556 873 1.7E-79 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 279 394 5.7E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Pfam PF08990 Erythronolide synthase docking 3 28 1.3E-10 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 184 200 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1177 1351 1.6E-38 T 28-03-2018 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Gene3D G3DSA:3.40.50.720 1169 1423 5.8E-53 T 28-03-2018 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Gene3D G3DSA:1.10.1200.10 1431 1529 1.4E-19 T 28-03-2018 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Pfam PF00550 Phosphopantetheine attachment site 1456 1522 7.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SMART SM00823 Phosphopantetheine attachment site 1454 1526 6.1E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF52151 554 683 1.44E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF52151 748 844 1.44E-62 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF51735 960 1165 2.68E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Gene3D G3DSA:3.40.47.10 25 276 3.9E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Pfam PF08659 KR domain 1177 1349 7.2E-49 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF55048 682 747 9.02E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF47336 1447 1532 1.83E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 271 1.8E-82 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SMART SM01294 1455 1522 3.2E-7 T 28-03-2018 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Gene3D G3DSA:3.40.366.10 742 861 2.3E-25 T 28-03-2018 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF53901 32 391 1.67E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SUPERFAMILY SSF101173 3 35 6.93E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Gene3D G3DSA:3.40.366.10 551 696 1.4E-41 T 28-03-2018 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SMART SM00825 Beta-ketoacyl synthase 37 447 1.8E-208 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 397 511 3.1E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 558 856 6.3E-103 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13585 f169085dc09aec175dcdd28acf2a53c1 1606 Gene3D G3DSA:3.40.47.10 286 445 1.1E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 PRINTS PR00364 Disease resistance protein signature 376 390 8.9E-8 T 28-03-2018 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 PRINTS PR00364 Disease resistance protein signature 461 475 8.9E-8 T 28-03-2018 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 PRINTS PR00364 Disease resistance protein signature 298 313 8.9E-8 T 28-03-2018 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SUPERFAMILY SSF52540 269 528 1.55E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SUPERFAMILY SSF48452 746 891 1.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Gene3D G3DSA:1.25.40.10 108 264 4.3E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SUPERFAMILY SSF48452 102 269 2.93E-38 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SUPERFAMILY SSF46894 15 99 7.37E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Gene3D G3DSA:1.10.10.10 18 107 2.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Gene3D G3DSA:1.25.40.10 883 973 8.0E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00382 295 439 0.0019 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Pfam PF00931 NB-ARC domain 285 474 1.3E-11 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Pfam PF00486 Transcriptional regulatory protein, C terminal 33 96 4.2E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Pfam PF03704 Bacterial transcriptional activator domain 106 251 2.8E-40 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SUPERFAMILY SSF48452 854 971 1.74E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Gene3D G3DSA:3.40.50.300 267 416 1.3E-15 T 28-03-2018 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM01043 106 251 1.6E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 Gene3D G3DSA:1.25.40.10 737 882 1.4E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00862 26 99 4.1E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00028 899 932 3.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00028 201 234 470.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00028 111 144 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00028 778 811 440.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00028 858 891 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26250 b0d83ddb5b2b58b312b6c7c2ff66f450 989 SMART SM00028 939 972 420.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS01870 a5ed18d72e2a4e4299428dc9a98dd363 162 Pfam PF02559 CarD-like/TRCF domain 3 111 1.3E-18 T 28-03-2018 IPR003711 CarD-like/TRCF domain CNX65_RS01870 a5ed18d72e2a4e4299428dc9a98dd363 162 SMART SM01058 2 112 1.6E-32 T 28-03-2018 IPR003711 CarD-like/TRCF domain CNX65_RS01870 a5ed18d72e2a4e4299428dc9a98dd363 162 SUPERFAMILY SSF141259 3 66 3.4E-14 T 28-03-2018 IPR003711 CarD-like/TRCF domain CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 ProSitePatterns PS60002 Phosphoketolase signature 1. 143 149 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 Gene3D G3DSA:3.40.50.920 605 789 2.6E-85 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 Pfam PF09363 XFP C-terminal domain 585 787 1.1E-92 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 Pfam PF09364 XFP N-terminal domain 10 384 1.5E-185 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 ProSitePatterns PS60003 Phosphoketolase signature 2. 156 174 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 SUPERFAMILY SSF52518 375 590 1.29E-22 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 Gene3D G3DSA:3.40.50.970 1 377 5.2E-89 T 28-03-2018 CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 Hamap MF_01403 Probable phosphoketolase. 4 789 40.783 T 28-03-2018 IPR023962 Probable phosphoketolase CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 SUPERFAMILY SSF52518 10 368 9.9E-73 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 PIRSF PIRSF017245 2 789 0.0 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 Gene3D G3DSA:3.40.50.970 378 599 2.7E-33 T 28-03-2018 CNX65_RS09580 1e9de6149c9da8aab07ca1822370cacd 789 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 398 574 6.8E-87 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CNX65_RS19610 404d24cb5e1696a705289ec1b7c7bc3b 657 Gene3D G3DSA:2.120.10.70 245 470 7.1E-14 T 28-03-2018 CNX65_RS19610 404d24cb5e1696a705289ec1b7c7bc3b 657 Gene3D G3DSA:2.120.10.70 471 606 4.7E-15 T 28-03-2018 CNX65_RS19610 404d24cb5e1696a705289ec1b7c7bc3b 657 Pfam PF14517 Tachylectin 56 294 8.4E-37 T 28-03-2018 IPR023294 Tachylectin 2 CNX65_RS19610 404d24cb5e1696a705289ec1b7c7bc3b 657 Gene3D G3DSA:2.120.10.70 17 188 0.15 T 28-03-2018 CNX65_RS19610 404d24cb5e1696a705289ec1b7c7bc3b 657 SUPERFAMILY SSF89372 434 635 1.7E-11 T 28-03-2018 CNX65_RS19610 404d24cb5e1696a705289ec1b7c7bc3b 657 SUPERFAMILY SSF50934 150 302 1.2E-12 T 28-03-2018 IPR023294 Tachylectin 2 CNX65_RS30175 e68039da2114beebff298b83068921aa 418 Gene3D G3DSA:3.65.10.10 221 418 5.0E-45 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS30175 e68039da2114beebff298b83068921aa 418 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 2 416 39.429 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS30175 e68039da2114beebff298b83068921aa 418 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 406 1.2E-101 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS30175 e68039da2114beebff298b83068921aa 418 Gene3D G3DSA:3.65.10.10 22 220 6.1E-49 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS30175 e68039da2114beebff298b83068921aa 418 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 3 415 5.3E-162 T 28-03-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS30175 e68039da2114beebff298b83068921aa 418 SUPERFAMILY SSF55205 4 417 3.27E-129 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 Pfam PF00582 Universal stress protein family 3 133 1.2E-23 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 Pfam PF00582 Universal stress protein family 143 267 2.9E-15 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 Gene3D G3DSA:3.40.50.620 1 135 4.7E-28 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 PRINTS PR01438 Universal stress protein signature 1 18 1.6E-15 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 PRINTS PR01438 Universal stress protein signature 111 133 1.6E-15 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 PRINTS PR01438 Universal stress protein signature 93 105 1.6E-15 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 SUPERFAMILY SSF52402 3 139 2.76E-28 T 28-03-2018 CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 Gene3D G3DSA:3.40.50.620 136 266 3.2E-21 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS12275 3bd67d1c3a754ba148cbadc2e050466c 281 SUPERFAMILY SSF52402 154 268 6.2E-19 T 28-03-2018 CNX65_RS34705 5768f5732059d85e52b7ed684e2b2acc 434 Gene3D G3DSA:2.30.40.10 2 67 8.0E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS34705 5768f5732059d85e52b7ed684e2b2acc 434 SUPERFAMILY SSF51338 354 433 2.06E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS34705 5768f5732059d85e52b7ed684e2b2acc 434 SUPERFAMILY SSF51338 9 77 3.02E-7 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS34705 5768f5732059d85e52b7ed684e2b2acc 434 SUPERFAMILY SSF51556 58 354 6.81E-84 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS34705 5768f5732059d85e52b7ed684e2b2acc 434 Gene3D G3DSA:3.20.20.140 68 353 5.6E-59 T 28-03-2018 CNX65_RS34705 5768f5732059d85e52b7ed684e2b2acc 434 Pfam PF01979 Amidohydrolase family 55 408 2.0E-58 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 SMART SM00852 175 311 1.9E-39 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 SUPERFAMILY SSF53218 172 316 2.49E-38 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 Gene3D G3DSA:3.40.980.10 145 322 1.7E-50 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 Pfam PF03454 MoeA C-terminal region (domain IV) 325 394 4.0E-17 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 Pfam PF03453 MoeA N-terminal region (domain I and II) 4 162 1.0E-41 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 SUPERFAMILY SSF63882 4 171 1.07E-46 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 172 307 4.2E-31 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 Gene3D G3DSA:2.40.340.10 323 392 8.9E-19 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 SUPERFAMILY SSF63867 320 394 1.11E-16 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 Gene3D G3DSA:2.170.190.11 56 136 4.4E-30 T 28-03-2018 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 Gene3D G3DSA:3.90.105.10 22 55 2.7E-11 T 28-03-2018 CNX65_RS02220 089c0a9b3983be478934c4ea0e024c2a 394 Pfam PF00994 Probable molybdopterin binding domain 176 310 6.0E-23 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 Gene3D G3DSA:3.30.310.20 5 106 2.5E-33 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 SUPERFAMILY SSF48150 111 283 1.12E-36 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 Gene3D G3DSA:1.10.340.30 107 250 9.4E-30 T 28-03-2018 CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 SUPERFAMILY SSF55945 6 101 1.73E-22 T 28-03-2018 CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 Gene3D G3DSA:1.10.1670.10 251 290 5.9E-12 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 SMART SM00478 130 286 5.6E-21 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 SMART SM01009 5 120 8.6E-39 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS08205 45427e9453bbebaec837b43dd895af1e 294 Pfam PF06029 AlkA N-terminal domain 6 120 2.0E-27 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS09330 9bf3555948637548c054c1a7cc24ba23 741 Gene3D G3DSA:2.60.40.290 27 135 6.0E-34 T 28-03-2018 CNX65_RS09330 9bf3555948637548c054c1a7cc24ba23 741 SMART SM00637 36 135 3.7E-40 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS09330 9bf3555948637548c054c1a7cc24ba23 741 Gene3D G3DSA:2.60.40.10 170 258 2.3E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09330 9bf3555948637548c054c1a7cc24ba23 741 SUPERFAMILY SSF69318 265 524 9.02E-11 T 28-03-2018 CNX65_RS09330 9bf3555948637548c054c1a7cc24ba23 741 Gene3D G3DSA:2.130.10.130 411 691 4.1E-6 T 28-03-2018 CNX65_RS09330 9bf3555948637548c054c1a7cc24ba23 741 Pfam PF00553 Cellulose binding domain 36 135 2.2E-31 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS09330 9bf3555948637548c054c1a7cc24ba23 741 SUPERFAMILY SSF49384 33 137 6.28E-30 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 Gene3D G3DSA:1.10.1660.10 55 126 3.1E-12 T 28-03-2018 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 SMART SM00422 1 69 4.7E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 8.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 8.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 8.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 Pfam PF13411 MerR HTH family regulatory protein 2 61 8.4E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 Gene3D G3DSA:1.10.1660.10 1 54 6.9E-19 T 28-03-2018 CNX65_RS32135 ce942f17bfa26bd542f5905a25824d47 127 SUPERFAMILY SSF46955 2 113 2.01E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS10015 e9166e638899749e6ae9782a1db396bd 422 ProSitePatterns PS00161 Isocitrate lyase signature. 183 188 - T 28-03-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824|GO:0008152 CNX65_RS10015 e9166e638899749e6ae9782a1db396bd 422 PIRSF PIRSF001362 1 422 6.5E-235 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CNX65_RS10015 e9166e638899749e6ae9782a1db396bd 422 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 5 245 1.9E-105 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CNX65_RS10015 e9166e638899749e6ae9782a1db396bd 422 SUPERFAMILY SSF51621 6 421 1.79E-155 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS10015 e9166e638899749e6ae9782a1db396bd 422 Gene3D G3DSA:3.20.20.60 2 404 1.1E-147 T 28-03-2018 CNX65_RS10015 e9166e638899749e6ae9782a1db396bd 422 Pfam PF00463 Isocitrate lyase family 246 412 1.7E-47 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CNX65_RS10015 e9166e638899749e6ae9782a1db396bd 422 Pfam PF00463 Isocitrate lyase family 9 245 4.0E-53 T 28-03-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 Gene3D G3DSA:3.20.20.120 145 362 3.6E-64 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 ProSitePatterns PS00909 Mandelate racemase / muconate lactonizing enzyme family signature 2. 204 235 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 43 137 9.0E-15 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 SUPERFAMILY SSF54826 9 138 2.21E-27 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 SMART SM00922 157 254 2.6E-28 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 Pfam PF13378 Enolase C-terminal domain-like 164 364 8.9E-65 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 Gene3D G3DSA:3.30.390.10 5 144 1.1E-32 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS20235 2c76671effdefffd2f3a67fd2fb53ae2 379 SUPERFAMILY SSF51604 125 366 1.44E-71 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS10870 71f64cc1170299e0e03537137dd4ddb9 118 SUPERFAMILY SSF47090 35 111 8.11E-9 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS10870 71f64cc1170299e0e03537137dd4ddb9 118 Gene3D G3DSA:1.10.101.10 29 115 3.1E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 Pfam PF08532 Beta-galactosidase trimerisation domain 392 584 8.4E-47 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 Pfam PF08533 Beta-galactosidase C-terminal domain 594 659 1.1E-6 T 28-03-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 Pfam PF02449 Beta-galactosidase 16 381 1.0E-142 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 SUPERFAMILY SSF52317 390 584 6.87E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 Gene3D G3DSA:3.20.20.80 8 372 2.3E-88 T 28-03-2018 CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 Gene3D G3DSA:2.60.40.1180 592 658 5.0E-16 T 28-03-2018 CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 SUPERFAMILY SSF51445 12 384 8.52E-114 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 PIRSF PIRSF001084 4 660 1.7E-231 T 28-03-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS11090 671177353b7dd5aec38ae1d7554e2ab1 660 Gene3D G3DSA:3.40.50.880 389 588 9.5E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 1.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 1.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 1.7E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 Pfam PF00106 short chain dehydrogenase 3 183 1.1E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 SUPERFAMILY SSF51735 2 248 7.95E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00185 9bf8c585fa24607918c101d27f5dc895 255 Gene3D G3DSA:3.40.50.720 3 244 3.1E-50 T 28-03-2018 CNX65_RS26610 f72d7cd9bf3862aa8d2602550e7686f7 348 SUPERFAMILY SSF54631 210 342 2.91E-17 T 28-03-2018 CNX65_RS26610 f72d7cd9bf3862aa8d2602550e7686f7 348 Gene3D G3DSA:3.10.580.10 196 346 7.0E-22 T 28-03-2018 CNX65_RS26610 f72d7cd9bf3862aa8d2602550e7686f7 348 Pfam PF01595 Domain of unknown function DUF21 9 202 1.6E-42 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 SUPERFAMILY SSF51735 8 261 5.04E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 Pfam PF00106 short chain dehydrogenase 9 190 9.3E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 8.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 8.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 8.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 8.4E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25360 de82e3e04a659fa4c2eaacc19dd740cd 296 Gene3D G3DSA:3.40.50.720 6 278 6.2E-60 T 28-03-2018 CNX65_RS03995 aee7d7fe5acd29c8e9d5ac2006e8debb 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 305 2.5E-7 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03995 aee7d7fe5acd29c8e9d5ac2006e8debb 318 Gene3D G3DSA:1.10.3720.10 37 308 7.4E-48 T 28-03-2018 CNX65_RS03995 aee7d7fe5acd29c8e9d5ac2006e8debb 318 SUPERFAMILY SSF161098 33 306 2.99E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17570 155cf707f4208e08adfac8d466c82ce3 196 Pfam PF11066 Protein of unknown function (DUF2867) 26 181 1.0E-24 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 CNX65_RS17175 1bfbecee032e9fea156abaa877df582e 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 1.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS17175 1bfbecee032e9fea156abaa877df582e 197 SUPERFAMILY SSF46689 8 82 1.25E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS17175 1bfbecee032e9fea156abaa877df582e 197 Gene3D G3DSA:1.10.357.10 3 196 4.4E-28 T 28-03-2018 CNX65_RS17175 1bfbecee032e9fea156abaa877df582e 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 7.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS17175 1bfbecee032e9fea156abaa877df582e 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 7.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 Gene3D G3DSA:3.40.50.720 235 467 1.4E-66 T 28-03-2018 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 SUPERFAMILY SSF53223 86 235 4.75E-56 T 28-03-2018 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 PRINTS PR00072 Malic enzyme signature 264 280 5.5E-6 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 PRINTS PR00072 Malic enzyme signature 233 249 5.5E-6 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 PRINTS PR00072 Malic enzyme signature 154 176 5.5E-6 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 Pfam PF00390 Malic enzyme, N-terminal domain 93 191 2.6E-24 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 SMART SM00919 237 459 1.1E-101 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 PIRSF PIRSF000106 27 467 2.8E-80 T 28-03-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 SMART SM01274 92 225 2.6E-84 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 SUPERFAMILY SSF51735 237 465 7.24E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 Pfam PF03949 Malic enzyme, NAD binding domain 239 458 3.8E-22 T 28-03-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 CNX65_RS02360 5c0a68fb2502040f44071893d9f20e77 467 Gene3D G3DSA:3.40.50.10380 84 234 8.7E-40 T 28-03-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 CNX65_RS03145 14ba1a2e3527726456e3caec1b851e93 712 Pfam PF00069 Protein kinase domain 434 678 2.8E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS03145 14ba1a2e3527726456e3caec1b851e93 712 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 439 462 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS03145 14ba1a2e3527726456e3caec1b851e93 712 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 549 561 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS03145 14ba1a2e3527726456e3caec1b851e93 712 Gene3D G3DSA:3.30.200.20 292 497 1.2E-23 T 28-03-2018 CNX65_RS03145 14ba1a2e3527726456e3caec1b851e93 712 Gene3D G3DSA:1.10.510.10 498 689 3.9E-40 T 28-03-2018 CNX65_RS03145 14ba1a2e3527726456e3caec1b851e93 712 SMART SM00220 433 686 4.5E-47 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS03145 14ba1a2e3527726456e3caec1b851e93 712 SUPERFAMILY SSF56112 423 679 3.64E-64 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 SMART SM00422 11 80 2.8E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 Pfam PF00376 MerR family regulatory protein 12 49 1.7E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 Gene3D G3DSA:1.10.1660.10 67 145 5.5E-7 T 28-03-2018 CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 Gene3D G3DSA:1.10.1660.10 7 66 1.1E-17 T 28-03-2018 CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 SUPERFAMILY SSF46955 12 113 9.16E-23 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 47 67 5.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 23 36 5.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18185 b209651175f7e2b6b49b9662eac2bb6e 278 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 12 23 5.4E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF55048 666 727 7.19E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 275 2.7E-81 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1647 1897 6.6E-89 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.366.10 718 837 2.2E-26 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF51735 1146 1283 1.42E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF55048 2290 2351 9.94E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2173 2467 2.9E-104 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 550 832 1.4E-105 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.30.70.250 677 717 2.8E-19 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.30.70.250 2301 2341 5.2E-19 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF08659 KR domain 1299 1461 1.7E-45 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.366.10 2342 2456 4.8E-22 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.366.10 2170 2300 2.2E-42 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.366.10 546 676 4.8E-42 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF53901 1644 2017 1.52E-106 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00826 884 1042 7.4E-57 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF00698 Acyl transferase domain 549 849 7.0E-51 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF00698 Acyl transferase domain 2173 2440 1.8E-52 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:1.10.1200.10 2545 2639 3.9E-19 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00823 Phosphopantetheine attachment site 2566 2638 2.8E-23 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00823 Phosphopantetheine attachment site 1555 1627 1.5E-34 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1299 1316 8.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 1364 1375 8.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00825 Beta-ketoacyl synthase 1649 2073 7.2E-226 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00825 Beta-ketoacyl synthase 37 451 5.5E-204 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.10.129.10 888 1007 2.8E-8 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF47336 1555 1662 4.32E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM01294 1560 1623 1.4E-7 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM01294 2567 2634 3.4E-4 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.47.10 290 449 7.1E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.47.10 1912 2071 2.7E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2023 2136 3.5E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 401 514 3.3E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:1.10.1200.10 1536 1635 2.0E-22 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 188 204 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF51735 1296 1515 4.17E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF47336 2562 2638 3.14E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF14765 Polyketide synthase dehydratase 891 1145 6.4E-47 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1298 1463 4.2E-45 T 28-03-2018 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF52151 728 821 2.62E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF52151 547 667 2.62E-66 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF53901 32 395 4.22E-96 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF00550 Phosphopantetheine attachment site 2568 2634 1.9E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF00550 Phosphopantetheine attachment site 1558 1623 5.5E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1905 2020 6.6E-46 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 283 398 4.4E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.47.10 1640 1909 5.5E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.47.10 28 287 9.6E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1582 1597 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1810 1826 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF52151 2171 2291 2.43E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 SUPERFAMILY SSF52151 2352 2441 2.43E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15345 39e03ee3e1a9ea4e181a5e8208b788f8 2641 Gene3D G3DSA:3.40.50.720 1292 1535 4.5E-46 T 28-03-2018 CNX65_RS00460 f5cab8084d99c9d39de366580a431f5c 219 Gene3D G3DSA:3.30.450.40 158 219 5.6E-6 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS00460 f5cab8084d99c9d39de366580a431f5c 219 Pfam PF09339 IclR helix-turn-helix domain 18 70 2.3E-11 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS00460 f5cab8084d99c9d39de366580a431f5c 219 SUPERFAMILY SSF55781 74 218 2.94E-18 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS00460 f5cab8084d99c9d39de366580a431f5c 219 Gene3D G3DSA:3.30.450.40 83 157 6.5E-16 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS00460 f5cab8084d99c9d39de366580a431f5c 219 SUPERFAMILY SSF46785 18 87 1.45E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00460 f5cab8084d99c9d39de366580a431f5c 219 SMART SM00346 16 103 5.6E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS00460 f5cab8084d99c9d39de366580a431f5c 219 Gene3D G3DSA:1.10.10.10 8 82 7.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Gene3D G3DSA:2.40.50.250 508 598 2.0E-35 T 28-03-2018 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Pfam PF03144 Elongation factor Tu domain 2 244 314 1.4E-11 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 SUPERFAMILY SSF54980 424 538 9.11E-27 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 PRINTS PR00315 GTP-binding elongation factor signature 19 32 3.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 PRINTS PR00315 GTP-binding elongation factor signature 103 114 3.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 PRINTS PR00315 GTP-binding elongation factor signature 139 148 3.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 PRINTS PR00315 GTP-binding elongation factor signature 63 71 3.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 PRINTS PR00315 GTP-binding elongation factor signature 87 97 3.3E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Gene3D G3DSA:3.40.50.300 6 212 1.3E-36 T 28-03-2018 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 SUPERFAMILY SSF52540 12 231 7.41E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 SUPERFAMILY SSF54980 327 413 1.44E-10 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Pfam PF00679 Elongation factor G C-terminus 423 506 6.5E-20 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Gene3D G3DSA:3.30.70.240 428 506 2.7E-17 T 28-03-2018 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 SUPERFAMILY SSF50447 172 325 7.28E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Pfam PF00009 Elongation factor Tu GTP binding domain 16 220 1.9E-51 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Gene3D G3DSA:3.30.70.870 327 427 2.1E-27 T 28-03-2018 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 Gene3D G3DSA:2.40.30.10 218 325 7.0E-25 T 28-03-2018 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 17 623 3.3E-271 T 28-03-2018 IPR006298 GTP-binding protein TypA GO:0005525 CNX65_RS03745 1bea6bd36ca46cf1c08ff437717fd2ab 633 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 18 157 7.3E-25 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS21790 ab0e672671a751a3ff6ca7b53602f611 507 Pfam PF00221 Aromatic amino acid lyase 25 476 3.9E-126 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CNX65_RS21790 ab0e672671a751a3ff6ca7b53602f611 507 Gene3D G3DSA:1.20.200.10 211 506 3.1E-77 T 28-03-2018 CNX65_RS21790 ab0e672671a751a3ff6ca7b53602f611 507 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 152 167 - T 28-03-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 CNX65_RS21790 ab0e672671a751a3ff6ca7b53602f611 507 Gene3D G3DSA:1.10.275.10 16 210 6.5E-54 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CNX65_RS21790 ab0e672671a751a3ff6ca7b53602f611 507 SUPERFAMILY SSF48557 22 504 7.85E-133 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 Pfam PF00553 Cellulose binding domain 42 141 1.8E-29 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 SUPERFAMILY SSF49384 38 142 1.88E-28 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 Gene3D G3DSA:3.40.50.1110 268 488 1.4E-20 T 28-03-2018 CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 SMART SM00637 42 141 1.0E-41 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 279 434 2.8E-12 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 SUPERFAMILY SSF52266 270 486 7.16E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 106 119 - T 28-03-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 CNX65_RS17720 3fc6f49a9e3bd05df437a7d72a0c4050 492 Gene3D G3DSA:2.60.40.290 32 141 6.5E-34 T 28-03-2018 CNX65_RS33635 07dd5ceb3740a83aa16f744b27ba9a28 215 SUPERFAMILY SSF56784 1 207 1.45E-34 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33635 07dd5ceb3740a83aa16f744b27ba9a28 215 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 84 172 2.0E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS33635 07dd5ceb3740a83aa16f744b27ba9a28 215 Gene3D G3DSA:3.40.50.1000 1 214 2.9E-28 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33635 07dd5ceb3740a83aa16f744b27ba9a28 215 Pfam PF13419 Haloacid dehalogenase-like hydrolase 78 177 2.0E-10 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33635 07dd5ceb3740a83aa16f744b27ba9a28 215 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 79 180 1.3E-12 T 28-03-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 15 86 1.0E-28 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 ProSitePatterns PS00056 Ribosomal protein S17 signature. 66 78 - T 28-03-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 SUPERFAMILY SSF50249 15 92 5.57E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 Pfam PF00366 Ribosomal protein S17 20 87 2.8E-29 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 Gene3D G3DSA:2.40.50.140 15 92 7.6E-28 T 28-03-2018 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 PRINTS PR00973 Ribosomal protein S17 family signature 66 76 1.1E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 PRINTS PR00973 Ribosomal protein S17 family signature 76 83 1.1E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 PRINTS PR00973 Ribosomal protein S17 family signature 34 57 1.1E-10 T 28-03-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 15 90 23.557 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32405 e60f8e7ff61cd3b0b92c4b7850beabf9 93 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 15 86 1.1E-32 T 28-03-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF08990 Erythronolide synthase docking 5 29 5.7E-10 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF14765 Polyketide synthase dehydratase 929 1171 1.4E-14 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SMART SM00823 Phosphopantetheine attachment site 1641 1711 8.8E-27 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF52151 564 692 3.4E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF52151 756 854 3.4E-72 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 197 213 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF08659 KR domain 1368 1539 1.8E-49 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF53901 34 406 6.49E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:1.10.1200.10 1620 1720 9.9E-19 T 28-03-2018 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:3.40.50.720 1361 1603 2.1E-44 T 28-03-2018 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF07993 Male sterility protein 1751 1988 7.5E-61 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF55048 691 755 1.7E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF51735 1184 1353 7.87E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SMART SM00825 Beta-ketoacyl synthase 38 460 2.3E-209 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 284 1.9E-89 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1749 2102 4.7E-97 T 28-03-2018 IPR010080 Thioester reductase-like domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 568 863 1.4E-110 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 410 527 8.9E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SMART SM01294 1646 1707 0.0015 T 28-03-2018 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1666 1681 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:3.40.47.10 28 296 5.3E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:3.30.70.250 702 740 6.2E-18 T 28-03-2018 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:3.40.47.10 299 458 7.1E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF00698 Acyl transferase domain 567 881 1.5E-58 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF51735 1366 1615 1.85E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:3.40.50.720 1745 2081 4.6E-37 T 28-03-2018 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1368 1540 7.7E-46 T 28-03-2018 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF00550 Phosphopantetheine attachment site 1646 1707 6.7E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SMART SM00826 929 1072 4.2E-31 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:3.40.366.10 741 868 9.2E-30 T 28-03-2018 CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF47336 1634 1718 3.14E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 292 407 2.7E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 SUPERFAMILY SSF51735 1749 2021 1.11E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23390 d8872829107841ef8ffddd40f23c4967 2113 Gene3D G3DSA:3.40.366.10 561 701 8.4E-48 T 28-03-2018 CNX65_RS28395 941982cdbdd9b8058b468f9251711792 415 Pfam PF00860 Permease family 31 382 1.2E-67 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS34120 bafa2d7b7dde160041e02c57315fbe3d 645 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 124 553 8.8E-59 T 28-03-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit CNX65_RS34120 bafa2d7b7dde160041e02c57315fbe3d 645 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 25 642 3.4E-130 T 28-03-2018 IPR011853 TRAP transporter, 4TM/12TM fusion protein CNX65_RS22420 d202d8d1f73207c9a2be235a6e57e84d 164 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 161 1.2E-57 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CNX65_RS17265 6bb7cdd3f9e982e53eb66d6ee8f73594 215 SUPERFAMILY SSF52540 18 184 2.01E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17265 6bb7cdd3f9e982e53eb66d6ee8f73594 215 Gene3D G3DSA:3.40.50.300 1 189 3.8E-27 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 Gene3D G3DSA:1.20.1250.20 9 201 4.3E-30 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 Gene3D G3DSA:1.20.1250.20 253 474 3.0E-34 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 Pfam PF07690 Major Facilitator Superfamily 15 411 6.3E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 339 359 8.5E-12 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 402 421 8.5E-12 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 8.5E-12 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 8.5E-12 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 8.5E-12 T 28-03-2018 CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 SUPERFAMILY SSF103473 6 198 4.71E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS24040 0af8ee51b5f7282a14617c7be081a93a 477 SUPERFAMILY SSF103473 249 468 4.71E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS26630 126e416e4a2dfc4c1090dd80eb1f5591 299 SUPERFAMILY SSF46785 229 295 1.79E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26630 126e416e4a2dfc4c1090dd80eb1f5591 299 Gene3D G3DSA:1.10.10.10 101 297 5.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26630 126e416e4a2dfc4c1090dd80eb1f5591 299 SMART SM00418 228 295 3.5E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS26630 126e416e4a2dfc4c1090dd80eb1f5591 299 Pfam PF12840 Helix-turn-helix domain 233 281 3.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26930 5a32a2514fef6a72d4cec6cd78652bd0 158 SUPERFAMILY SSF53927 15 153 2.01E-33 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS26930 5a32a2514fef6a72d4cec6cd78652bd0 158 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 15 107 2.5E-16 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CNX65_RS26930 5a32a2514fef6a72d4cec6cd78652bd0 158 Gene3D G3DSA:3.40.140.10 2 155 3.4E-32 T 28-03-2018 CNX65_RS18795 f74b3649d1cc2a2ba9c2d6574fa3e79a 246 Gene3D G3DSA:3.30.750.24 1 168 2.4E-6 T 28-03-2018 IPR002645 STAS domain CNX65_RS18795 f74b3649d1cc2a2ba9c2d6574fa3e79a 246 SUPERFAMILY SSF52091 5 87 8.24E-7 T 28-03-2018 IPR002645 STAS domain CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 Pfam PF00561 alpha/beta hydrolase fold 21 251 2.5E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 SUPERFAMILY SSF53474 1 263 8.63E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 4.8E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 4.8E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 4.8E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 PRINTS PR00111 Alpha/beta hydrolase fold signature 102 115 4.8E-8 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 Gene3D G3DSA:3.40.50.1820 3 264 2.3E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 PRINTS PR00412 Epoxide hydrolase signature 47 62 2.7E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 PRINTS PR00412 Epoxide hydrolase signature 102 115 2.7E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS27615 aaeaf2da60d2a68888630c9f32c39af7 264 PRINTS PR00412 Epoxide hydrolase signature 239 261 2.7E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS15075 5b7dd8826807d88733d9bb63e1754524 188 Pfam PF01381 Helix-turn-helix 16 70 1.9E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS15075 5b7dd8826807d88733d9bb63e1754524 188 SMART SM00530 15 70 6.2E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS15075 5b7dd8826807d88733d9bb63e1754524 188 Pfam PF07883 Cupin domain 117 172 2.0E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CNX65_RS15075 5b7dd8826807d88733d9bb63e1754524 188 Gene3D G3DSA:2.60.120.10 69 188 9.4E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS15075 5b7dd8826807d88733d9bb63e1754524 188 SUPERFAMILY SSF51182 22 178 1.04E-15 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS15075 5b7dd8826807d88733d9bb63e1754524 188 SUPERFAMILY SSF47413 11 74 1.86E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS15075 5b7dd8826807d88733d9bb63e1754524 188 Gene3D G3DSA:1.10.260.40 1 68 2.4E-18 T 28-03-2018 CNX65_RS01175 8edb3314dac13f0cbfe865f9e4d9b273 266 Pfam PF00753 Metallo-beta-lactamase superfamily 38 196 4.0E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS01175 8edb3314dac13f0cbfe865f9e4d9b273 266 Gene3D G3DSA:3.60.15.10 41 265 9.7E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS01175 8edb3314dac13f0cbfe865f9e4d9b273 266 SMART SM00849 41 196 4.8E-27 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS01175 8edb3314dac13f0cbfe865f9e4d9b273 266 SUPERFAMILY SSF56281 20 265 2.24E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 Pfam PF00196 Bacterial regulatory proteins, luxR family 888 943 1.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 Gene3D G3DSA:1.10.10.10 764 953 3.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 Gene3D G3DSA:1.25.40.10 495 691 7.8E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 Gene3D G3DSA:3.40.50.300 10 208 8.4E-13 T 28-03-2018 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 903 919 4.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 919 931 4.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 889 903 4.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 SMART SM00421 886 943 7.4E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 SUPERFAMILY SSF52540 123 255 2.66E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 SUPERFAMILY SSF52540 23 60 2.66E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 Gene3D G3DSA:1.25.40.10 382 494 0.041 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 ProSitePatterns PS00622 LuxR-type HTH domain signature. 903 930 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 SUPERFAMILY SSF46894 884 950 3.74E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 Pfam PF13191 AAA ATPase domain 9 187 7.1E-26 T 28-03-2018 CNX65_RS27800 23d0b50aa4c8e0bab717b62f6b189278 953 SUPERFAMILY SSF48452 494 635 3.8E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS12240 2796de51c6d5a05ba9eb3d9e24d78ce5 276 SUPERFAMILY SSF161098 8 275 5.98E-64 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12240 2796de51c6d5a05ba9eb3d9e24d78ce5 276 Gene3D G3DSA:1.10.3720.10 2 264 6.1E-45 T 28-03-2018 CNX65_RS12240 2796de51c6d5a05ba9eb3d9e24d78ce5 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 261 1.2E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS01750 f4eb8237727353976c236ab3f2a5e5ff 248 Gene3D G3DSA:3.40.50.1820 1 248 1.1E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS01750 f4eb8237727353976c236ab3f2a5e5ff 248 SUPERFAMILY SSF53474 4 242 3.08E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS01750 f4eb8237727353976c236ab3f2a5e5ff 248 Pfam PF12697 Alpha/beta hydrolase family 13 233 5.6E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS19980 4c670ee813867dcb833694e391c3f1a5 247 Pfam PF13411 MerR HTH family regulatory protein 4 68 9.6E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS19980 4c670ee813867dcb833694e391c3f1a5 247 Gene3D G3DSA:1.10.1660.10 2 56 4.0E-17 T 28-03-2018 CNX65_RS19980 4c670ee813867dcb833694e391c3f1a5 247 Gene3D G3DSA:1.10.1660.10 57 115 6.2E-7 T 28-03-2018 CNX65_RS19980 4c670ee813867dcb833694e391c3f1a5 247 SMART SM00422 3 72 4.9E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS19980 4c670ee813867dcb833694e391c3f1a5 247 SUPERFAMILY SSF46955 4 106 3.08E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS23750 f2b11108a697b43a25a54f054fcd184b 263 SUPERFAMILY SSF52540 5 227 3.09E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23750 f2b11108a697b43a25a54f054fcd184b 263 Pfam PF00005 ABC transporter 21 169 1.6E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS23750 f2b11108a697b43a25a54f054fcd184b 263 Gene3D G3DSA:3.40.50.300 2 237 3.4E-61 T 28-03-2018 CNX65_RS23750 f2b11108a697b43a25a54f054fcd184b 263 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS23750 f2b11108a697b43a25a54f054fcd184b 263 SMART SM00382 29 214 3.0E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 SUPERFAMILY SSF51905 17 185 2.65E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 SUPERFAMILY SSF51905 288 395 2.65E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 SUPERFAMILY SSF54373 188 289 2.43E-31 T 28-03-2018 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 Gene3D G3DSA:3.50.50.60 1 170 1.2E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 Pfam PF01494 FAD binding domain 16 356 8.8E-67 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 Gene3D G3DSA:3.30.9.10 171 297 2.2E-45 T 28-03-2018 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 Gene3D G3DSA:3.30.9.10 333 399 6.1E-15 T 28-03-2018 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 2.6E-23 T 28-03-2018 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 292 307 2.6E-23 T 28-03-2018 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 2.6E-23 T 28-03-2018 CNX65_RS26985 df9a8273423217d9d67e0e4c536d4de5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 307 323 2.6E-23 T 28-03-2018 CNX65_RS13515 fb7cb188256a8e5180f43e44a730b7bb 415 SMART SM01209 113 294 2.9E-4 T 28-03-2018 CNX65_RS13515 fb7cb188256a8e5180f43e44a730b7bb 415 Pfam PF13535 ATP-grasp domain 149 297 2.5E-14 T 28-03-2018 CNX65_RS13515 fb7cb188256a8e5180f43e44a730b7bb 415 SUPERFAMILY SSF56059 106 331 1.68E-36 T 28-03-2018 CNX65_RS13515 fb7cb188256a8e5180f43e44a730b7bb 415 Gene3D G3DSA:3.40.50.20 29 121 2.0E-4 T 28-03-2018 CNX65_RS13515 fb7cb188256a8e5180f43e44a730b7bb 415 Gene3D G3DSA:3.30.470.20 202 408 4.0E-22 T 28-03-2018 CNX65_RS13515 fb7cb188256a8e5180f43e44a730b7bb 415 Gene3D G3DSA:3.30.1490.20 122 201 5.4E-21 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 TIGRFAM TIGR03450 mycothiol_INO1: inositol 1-phosphate synthase 8 357 2.6E-212 T 28-03-2018 IPR017815 Myo-inositol 1-phosphate synthase, actinobacteria CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 PIRSF PIRSF015578 1 363 1.9E-94 T 28-03-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 Pfam PF01658 Myo-inositol-1-phosphate synthase 195 303 1.9E-32 T 28-03-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 Gene3D G3DSA:3.40.50.720 297 358 1.9E-15 T 28-03-2018 CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 Gene3D G3DSA:3.40.50.720 1 205 1.4E-57 T 28-03-2018 CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 SUPERFAMILY SSF51735 8 189 9.84E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 SUPERFAMILY SSF51735 300 359 9.84E-95 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 SUPERFAMILY SSF55347 194 302 1.1E-34 T 28-03-2018 CNX65_RS34740 362a8fd103101530e5a5fd0e416d44c6 363 Gene3D G3DSA:3.30.360.10 206 296 1.4E-36 T 28-03-2018 CNX65_RS08265 329137a9f6cc9c4700be7e4781cf6036 740 Pfam PF04389 Peptidase family M28 108 296 4.9E-36 T 28-03-2018 IPR007484 Peptidase M28 CNX65_RS08265 329137a9f6cc9c4700be7e4781cf6036 740 Gene3D G3DSA:3.40.630.10 34 308 4.1E-47 T 28-03-2018 CNX65_RS08265 329137a9f6cc9c4700be7e4781cf6036 740 SUPERFAMILY SSF53187 42 304 5.19E-49 T 28-03-2018 CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 Gene3D G3DSA:3.40.50.720 12 299 2.0E-49 T 28-03-2018 CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 13 203 0.009 T 28-03-2018 CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 SUPERFAMILY SSF51735 14 262 1.62E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 Pfam PF00106 short chain dehydrogenase 14 209 1.4E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 2.2E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 156 2.2E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 14 31 2.2E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 2.2E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16590 ad6db5e21d7b58594f5f2804f31ab4b7 308 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 2.2E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15195 86367713fc8660ef367c5c2a15ef7cb3 270 Pfam PF04954 Siderophore-interacting protein 149 265 1.6E-30 T 28-03-2018 IPR007037 Siderophore-interacting protein CNX65_RS15195 86367713fc8660ef367c5c2a15ef7cb3 270 Gene3D G3DSA:3.40.50.80 142 269 1.1E-36 T 28-03-2018 CNX65_RS15195 86367713fc8660ef367c5c2a15ef7cb3 270 Gene3D G3DSA:2.40.30.10 6 141 2.3E-31 T 28-03-2018 CNX65_RS15195 86367713fc8660ef367c5c2a15ef7cb3 270 Pfam PF08021 Siderophore-interacting FAD-binding domain 18 137 3.4E-30 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CNX65_RS15195 86367713fc8660ef367c5c2a15ef7cb3 270 SUPERFAMILY SSF63380 13 144 4.97E-9 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS00655 54f9fd9d5d4e0f4cbd78122c7fe5f551 267 Pfam PF17210 SdrD B-like domain 32 93 2.6E-8 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS00655 54f9fd9d5d4e0f4cbd78122c7fe5f551 267 SUPERFAMILY SSF117074 25 81 3.14E-8 T 28-03-2018 CNX65_RS00655 54f9fd9d5d4e0f4cbd78122c7fe5f551 267 Gene3D G3DSA:2.60.40.10 28 262 7.7E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 Gene3D G3DSA:1.20.1250.20 303 513 2.8E-22 T 28-03-2018 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 48 459 4.7E-74 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 ProSitePatterns PS00217 Sugar transport proteins signature 2. 144 169 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 Pfam PF07690 Major Facilitator Superfamily 53 455 5.1E-56 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 Gene3D G3DSA:1.20.1250.20 42 240 4.8E-40 T 28-03-2018 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 142 162 3.3E-9 T 28-03-2018 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 172 196 3.3E-9 T 28-03-2018 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 PRINTS PR01036 Tetracycline resistance protein TetB signature 51 75 3.3E-9 T 28-03-2018 CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 SUPERFAMILY SSF103473 26 233 1.09E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13180 6021a7956c70030f874189432a0085c4 517 SUPERFAMILY SSF103473 292 502 1.09E-75 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS14250 534272febe3131052aa892c573123f1d 302 Gene3D G3DSA:3.40.50.300 2 261 1.7E-62 T 28-03-2018 CNX65_RS14250 534272febe3131052aa892c573123f1d 302 SMART SM00382 32 224 1.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS14250 534272febe3131052aa892c573123f1d 302 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS14250 534272febe3131052aa892c573123f1d 302 SUPERFAMILY SSF52540 7 228 1.51E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14250 534272febe3131052aa892c573123f1d 302 Pfam PF00005 ABC transporter 24 167 6.4E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 SMART SM00422 1 64 0.016 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 SMART SM00422 116 184 3.4E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 Gene3D G3DSA:1.10.1660.10 1 93 5.5E-14 T 28-03-2018 CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 SUPERFAMILY SSF46955 117 222 6.87E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 Gene3D G3DSA:1.10.10.10 94 122 0.015 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 Pfam PF13411 MerR HTH family regulatory protein 118 182 4.5E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 Gene3D G3DSA:1.10.1660.10 123 226 9.9E-23 T 28-03-2018 CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 SUPERFAMILY SSF46955 3 106 1.14E-10 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS17730 8e714ce87c9dc0f238364df064d1882f 227 Pfam PF00376 MerR family regulatory protein 5 39 9.4E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS10520 4459c76182fcae2d9fb925e9f5e97fc8 480 Pfam PF08309 LVIVD repeat 425 454 0.72 T 28-03-2018 IPR013211 LVIVD CNX65_RS10520 4459c76182fcae2d9fb925e9f5e97fc8 480 SUPERFAMILY SSF75011 148 451 4.45E-9 T 28-03-2018 CNX65_RS10520 4459c76182fcae2d9fb925e9f5e97fc8 480 Gene3D G3DSA:2.130.10.10 231 474 2.0E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 116 129 - T 28-03-2018 IPR033135 ClpP, histidine active site CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 PRINTS PR00127 Clp protease catalytic subunit P signature 94 111 6.6E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 PRINTS PR00127 Clp protease catalytic subunit P signature 63 83 6.6E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 PRINTS PR00127 Clp protease catalytic subunit P signature 115 134 6.6E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 PRINTS PR00127 Clp protease catalytic subunit P signature 23 38 6.6E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 PRINTS PR00127 Clp protease catalytic subunit P signature 172 191 6.6E-42 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 Pfam PF00574 Clp protease 22 196 4.3E-74 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 8 197 38.854 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 Gene3D G3DSA:3.90.226.10 25 197 5.0E-37 T 28-03-2018 CNX65_RS05515 01aa6a45ffc401e0abce4246bf09f7a7 205 SUPERFAMILY SSF52096 23 198 3.13E-62 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS05130 7acf59d17c71d595970307d63ecfe18d 157 SUPERFAMILY SSF52833 5 156 6.26E-48 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS05130 7acf59d17c71d595970307d63ecfe18d 157 PIRSF PIRSF000239 1 157 9.0E-18 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS05130 7acf59d17c71d595970307d63ecfe18d 157 Pfam PF00578 AhpC/TSA family 9 136 3.9E-37 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS05130 7acf59d17c71d595970307d63ecfe18d 157 Gene3D G3DSA:3.40.30.10 1 157 3.3E-43 T 28-03-2018 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 Gene3D G3DSA:1.25.10.10 646 931 1.1E-7 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 Gene3D G3DSA:1.25.10.10 932 1439 7.1E-8 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SMART SM00567 E-Z type HEAT repeats 1403 1435 520.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SMART SM00567 E-Z type HEAT repeats 575 608 120.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SMART SM00567 E-Z type HEAT repeats 792 824 140.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SMART SM00567 E-Z type HEAT repeats 900 932 500.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SMART SM00567 E-Z type HEAT repeats 1677 1705 120.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SMART SM00567 E-Z type HEAT repeats 1540 1570 340.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SUPERFAMILY SSF52540 231 310 3.22E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SUPERFAMILY SSF52540 132 202 3.22E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 Gene3D G3DSA:1.25.10.10 1497 1705 5.1E-4 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 Pfam PF05729 NACHT domain 144 309 2.0E-9 T 28-03-2018 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 Gene3D G3DSA:3.40.50.300 126 312 9.1E-7 T 28-03-2018 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SUPERFAMILY SSF48371 731 847 6.24E-11 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SUPERFAMILY SSF48371 1154 1214 6.24E-11 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SUPERFAMILY SSF48371 564 626 6.24E-11 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 SUPERFAMILY SSF48371 1371 1467 6.24E-11 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS07345 1384c09f4498986dc291dd64619575ec 1707 Gene3D G3DSA:1.25.40.70 523 627 0.0028 T 28-03-2018 CNX65_RS04710 39154fb8ebe318abe249e3dbf37ec95c 254 Gene3D G3DSA:3.40.30.10 83 254 3.6E-39 T 28-03-2018 CNX65_RS04710 39154fb8ebe318abe249e3dbf37ec95c 254 SUPERFAMILY SSF52833 80 252 1.91E-28 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS04710 39154fb8ebe318abe249e3dbf37ec95c 254 Pfam PF13462 Thioredoxin 84 251 3.6E-25 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 310 339 2.2E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 387 414 2.2E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 416 445 2.2E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 19 44 2.2E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 464 493 2.2E-29 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 348 511 1.0E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 Pfam PF12729 Four helix bundle sensory module for signal transduction 18 147 6.0E-8 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 SMART SM00304 229 281 9.2E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 SMART SM00304 417 477 94.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 SMART SM00283 289 543 6.4E-59 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 Gene3D G3DSA:1.20.120.230 160 332 4.9E-8 T 28-03-2018 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 SUPERFAMILY SSF58104 249 542 8.11E-65 T 28-03-2018 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 Pfam PF00672 HAMP domain 229 277 7.9E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS01925 45a21d849136d2f63c2fb9b839bd8fa3 544 Gene3D G3DSA:1.10.287.950 333 544 4.3E-48 T 28-03-2018 CNX65_RS24615 4484c5dd6716f2b5be82bfbe6ad426f4 99 Pfam PF01817 Chorismate mutase type II 25 77 8.7E-9 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS24615 4484c5dd6716f2b5be82bfbe6ad426f4 99 Gene3D G3DSA:1.20.59.10 8 95 4.8E-13 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS24615 4484c5dd6716f2b5be82bfbe6ad426f4 99 SMART SM00830 25 92 9.8E-5 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS24615 4484c5dd6716f2b5be82bfbe6ad426f4 99 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 21 93 1.4E-25 T 28-03-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal CNX65_RS24615 4484c5dd6716f2b5be82bfbe6ad426f4 99 SUPERFAMILY SSF48600 20 85 1.1E-11 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 SUPERFAMILY SSF56672 26 261 1.69E-83 T 28-03-2018 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Pfam PF11799 impB/mucB/samB family C-terminal domain 262 372 7.7E-21 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Hamap MF_01113 DNA polymerase IV [dinB]. 27 377 36.294 T 28-03-2018 IPR022880 DNA polymerase IV GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Gene3D G3DSA:1.10.150.20 197 265 3.6E-23 T 28-03-2018 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 SUPERFAMILY SSF100879 267 363 3.34E-27 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Pfam PF11798 IMS family HHH motif 193 223 8.8E-8 T 28-03-2018 IPR024728 DNA polymerase type-Y, HhH motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5655862|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Gene3D G3DSA:3.30.1490.100 266 379 2.5E-29 T 28-03-2018 IPR017961 DNA polymerase, Y-family, little finger domain GO:0003684|GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Pfam PF00817 impB/mucB/samB family 33 179 4.1E-47 T 28-03-2018 IPR001126 UmuC domain GO:0006281 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7|Reactome: R-HSA-5656169 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Gene3D G3DSA:3.30.70.270 142 196 1.8E-15 T 28-03-2018 CNX65_RS28345 c0e0966bcf59b12aecc2ea7119824cda 430 Gene3D G3DSA:3.30.70.270 66 141 3.9E-24 T 28-03-2018 CNX65_RS00825 914a87c3868f8602f7522f0748b9bc8f 416 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 381 414 0.0023 T 28-03-2018 CNX65_RS00825 914a87c3868f8602f7522f0748b9bc8f 416 TIGRFAM TIGR03934 TQXA_dom: TQXA domain 122 168 1.1E-16 T 28-03-2018 IPR023849 Uncharacterised domain CHP03934, TQXA CNX65_RS00825 914a87c3868f8602f7522f0748b9bc8f 416 Pfam PF08341 Thioester domain 118 181 1.3E-8 T 28-03-2018 IPR013552 Thioester domain CNX65_RS18600 ef9d115be7f8a798a14b9a659ed47b27 459 SUPERFAMILY SSF102114 153 417 2.31E-12 T 28-03-2018 CNX65_RS18600 ef9d115be7f8a798a14b9a659ed47b27 459 Gene3D G3DSA:3.20.20.70 151 428 6.3E-11 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 Pfam PF01386 Ribosomal L25p family 6 92 1.4E-24 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 4 180 25.886 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 Gene3D G3DSA:2.40.240.10 3 94 4.9E-29 T 28-03-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, beta-barrel domain Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 6 176 8.6E-51 T 28-03-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 11 91 2.0E-19 T 28-03-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 SUPERFAMILY SSF50715 11 176 4.71E-49 T 28-03-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 100 177 1.3E-19 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CNX65_RS03245 b7c8dd321d369622ec779b0939be8887 197 Gene3D G3DSA:2.170.120.20 99 184 1.7E-21 T 28-03-2018 IPR020057 Ribosomal protein L25, beta domain CNX65_RS15465 440bae1ac50ef2c3c27938aae1316036 468 SUPERFAMILY SSF53067 234 432 1.3E-31 T 28-03-2018 CNX65_RS15465 440bae1ac50ef2c3c27938aae1316036 468 Gene3D G3DSA:3.30.420.40 2 220 8.1E-38 T 28-03-2018 CNX65_RS15465 440bae1ac50ef2c3c27938aae1316036 468 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 5 224 1.7E-17 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CNX65_RS15465 440bae1ac50ef2c3c27938aae1316036 468 SUPERFAMILY SSF53067 3 227 6.05E-39 T 28-03-2018 CNX65_RS15465 440bae1ac50ef2c3c27938aae1316036 468 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 235 422 7.3E-32 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CNX65_RS15465 440bae1ac50ef2c3c27938aae1316036 468 Gene3D G3DSA:3.30.420.40 221 465 4.2E-44 T 28-03-2018 CNX65_RS23265 ad4c389cf1f0a4d2ce5a588991eb479d 285 SUPERFAMILY SSF52266 45 256 1.57E-49 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS23265 ad4c389cf1f0a4d2ce5a588991eb479d 285 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 49 242 1.2E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS23265 ad4c389cf1f0a4d2ce5a588991eb479d 285 Gene3D G3DSA:3.40.50.1110 44 264 2.7E-30 T 28-03-2018 CNX65_RS18315 03910ce0465b1652c08cb24e44702c09 342 Gene3D G3DSA:3.60.130.10 16 339 1.2E-51 T 28-03-2018 CNX65_RS18315 03910ce0465b1652c08cb24e44702c09 342 SUPERFAMILY SSF51197 68 333 1.33E-48 T 28-03-2018 CNX65_RS18315 03910ce0465b1652c08cb24e44702c09 342 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 71 319 3.0E-8 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CNX65_RS18315 03910ce0465b1652c08cb24e44702c09 342 PIRSF PIRSF019543 3 342 1.1E-108 T 28-03-2018 IPR014503 Clavaminate synthase-like GO:0005506|GO:0016491|GO:0055114 CNX65_RS04410 0a4498be5336f37e3d5e7616796893bf 251 SUPERFAMILY SSF53807 15 247 6.28E-29 T 28-03-2018 CNX65_RS04410 0a4498be5336f37e3d5e7616796893bf 251 Gene3D G3DSA:3.40.50.1980 107 247 1.2E-10 T 28-03-2018 CNX65_RS04410 0a4498be5336f37e3d5e7616796893bf 251 Gene3D G3DSA:3.40.50.1980 1 106 1.1E-20 T 28-03-2018 CNX65_RS23455 22020796a898c40446c4b200b30e7950 851 Gene3D G3DSA:2.60.40.10 780 844 2.3E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS23455 22020796a898c40446c4b200b30e7950 851 Gene3D G3DSA:2.60.40.650 671 779 3.9E-5 T 28-03-2018 CNX65_RS23455 22020796a898c40446c4b200b30e7950 851 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 10 514 1.6E-79 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CNX65_RS23455 22020796a898c40446c4b200b30e7950 851 SUPERFAMILY SSF48208 66 99 1.36E-15 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS23455 22020796a898c40446c4b200b30e7950 851 SUPERFAMILY SSF48208 132 349 1.36E-15 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS23455 22020796a898c40446c4b200b30e7950 851 Gene3D G3DSA:1.50.10.20 23 210 5.0E-16 T 28-03-2018 CNX65_RS23455 22020796a898c40446c4b200b30e7950 851 Gene3D G3DSA:1.50.10.10 211 458 3.2E-14 T 28-03-2018 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 Gene3D G3DSA:3.30.420.40 2 235 9.2E-55 T 28-03-2018 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 SUPERFAMILY SSF53067 241 475 6.48E-55 T 28-03-2018 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 PIRSF PIRSF000538 4 476 3.7E-110 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 343 363 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 238 6.8E-41 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 Gene3D G3DSA:3.30.420.40 236 476 5.0E-56 T 28-03-2018 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 247 427 2.5E-29 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CNX65_RS01025 66e65520e50b27ef6516e1f21985d71c 476 SUPERFAMILY SSF53067 7 241 1.23E-49 T 28-03-2018 CNX65_RS08015 ae5d5fd8cc3c1e6d548e1575f1f082f0 262 Pfam PF01553 Acyltransferase 74 198 1.0E-17 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS08015 ae5d5fd8cc3c1e6d548e1575f1f082f0 262 Gene3D G3DSA:3.40.1130.10 39 259 1.3E-33 T 28-03-2018 CNX65_RS08015 ae5d5fd8cc3c1e6d548e1575f1f082f0 262 SMART SM00563 89 201 8.7E-26 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS08015 ae5d5fd8cc3c1e6d548e1575f1f082f0 262 SUPERFAMILY SSF69593 60 258 6.15E-34 T 28-03-2018 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 ProSitePatterns PS00117 Galactose-1-phosphate uridyl transferase family 1 active site signature. 174 191 - T 28-03-2018 IPR019779 Galactose-1-phosphate uridyl transferase, class I His-active site KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 SUPERFAMILY SSF54197 203 360 1.33E-36 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 SUPERFAMILY SSF54197 38 199 3.21E-52 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 210 358 1.7E-21 T 28-03-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 PIRSF PIRSF000808 33 361 3.2E-111 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 40 198 1.1E-37 T 28-03-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 Gene3D G3DSA:3.30.428.10 199 361 4.5E-31 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 TIGRFAM TIGR00209 galT_1: galactose-1-phosphate uridylyltransferase 44 359 2.2E-51 T 28-03-2018 IPR001937 Galactose-1-phosphate uridyl transferase, class I GO:0008108|GO:0008270|GO:0033499 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-70370 CNX65_RS03080 c47e7816d1e1e826115deda7095a7ff8 361 Gene3D G3DSA:3.30.428.10 65 198 1.4E-42 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS25720 f13e17d22e197b46c80efa8af0f5ee4d 147 SMART SM00960 13 103 8.2E-28 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS25720 f13e17d22e197b46c80efa8af0f5ee4d 147 Pfam PF03259 Roadblock/LC7 domain 14 103 1.7E-20 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS25720 f13e17d22e197b46c80efa8af0f5ee4d 147 SUPERFAMILY SSF103196 7 130 7.85E-33 T 28-03-2018 CNX65_RS25720 f13e17d22e197b46c80efa8af0f5ee4d 147 Gene3D G3DSA:3.30.450.30 8 135 1.1E-41 T 28-03-2018 CNX65_RS06640 89a73e689a0b72263e5cafa72d9a03ee 332 SUPERFAMILY SSF56601 225 312 2.14E-7 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS06640 89a73e689a0b72263e5cafa72d9a03ee 332 SUPERFAMILY SSF56601 47 191 2.14E-7 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS06640 89a73e689a0b72263e5cafa72d9a03ee 332 Gene3D G3DSA:3.40.710.10 40 318 1.3E-6 T 28-03-2018 CNX65_RS06640 89a73e689a0b72263e5cafa72d9a03ee 332 Pfam PF13354 Beta-lactamase enzyme family 118 253 1.0E-5 T 28-03-2018 CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 Gene3D G3DSA:1.10.10.60 11 66 3.2E-16 T 28-03-2018 CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 Pfam PF16859 Bacterial transcriptional repressor C-terminal 76 185 6.2E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 Gene3D G3DSA:1.10.357.10 67 194 1.1E-17 T 28-03-2018 CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 65 3.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 2.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 2.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 SUPERFAMILY SSF48498 77 191 2.48E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS20050 aa57aa971c5ef2d414adde27aa26a4bb 195 SUPERFAMILY SSF46689 10 72 5.99E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS06255 dd21447b18ec9bebe5756af501f36507 250 SUPERFAMILY SSF57863 84 233 1.07E-41 T 28-03-2018 CNX65_RS06255 dd21447b18ec9bebe5756af501f36507 250 SUPERFAMILY SSF50249 3 80 2.57E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS06255 dd21447b18ec9bebe5756af501f36507 250 TIGRFAM TIGR00613 reco: DNA repair protein RecO 6 240 4.1E-34 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CNX65_RS06255 dd21447b18ec9bebe5756af501f36507 250 Pfam PF02565 Recombination protein O C terminal 86 239 1.9E-36 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CNX65_RS06255 dd21447b18ec9bebe5756af501f36507 250 Pfam PF11967 Recombination protein O N terminal 4 80 7.9E-26 T 28-03-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal CNX65_RS06255 dd21447b18ec9bebe5756af501f36507 250 Hamap MF_00201 DNA repair protein RecO [recO]. 3 244 27.043 T 28-03-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 CNX65_RS06255 dd21447b18ec9bebe5756af501f36507 250 Gene3D G3DSA:2.40.50.140 2 82 2.1E-28 T 28-03-2018 CNX65_RS30630 73d4ea1ccf1f96e8a09ddf58df78f297 612 SUPERFAMILY SSF51905 524 573 2.59E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30630 73d4ea1ccf1f96e8a09ddf58df78f297 612 SUPERFAMILY SSF51905 7 192 2.59E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30630 73d4ea1ccf1f96e8a09ddf58df78f297 612 Gene3D G3DSA:3.50.50.60 2 612 1.6E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30630 73d4ea1ccf1f96e8a09ddf58df78f297 612 Pfam PF13454 FAD-NAD(P)-binding 8 185 7.5E-38 T 28-03-2018 CNX65_RS20610 828f12d8891caf240675a83060a87adf 655 Gene3D G3DSA:2.130.10.130 133 322 8.1E-14 T 28-03-2018 CNX65_RS20610 828f12d8891caf240675a83060a87adf 655 Gene3D G3DSA:2.130.10.130 324 546 1.4E-14 T 28-03-2018 CNX65_RS20610 828f12d8891caf240675a83060a87adf 655 Pfam PF07593 ASPIC and UnbV 575 633 4.5E-12 T 28-03-2018 IPR011519 ASPIC/UnbV CNX65_RS20610 828f12d8891caf240675a83060a87adf 655 Pfam PF01839 FG-GAP repeat 204 223 8.1E-5 T 28-03-2018 IPR013517 FG-GAP repeat Reactome: R-HSA-216083 CNX65_RS20610 828f12d8891caf240675a83060a87adf 655 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 295 369 6.5E-7 T 28-03-2018 CNX65_RS20610 828f12d8891caf240675a83060a87adf 655 SUPERFAMILY SSF69318 478 543 3.53E-52 T 28-03-2018 CNX65_RS20610 828f12d8891caf240675a83060a87adf 655 SUPERFAMILY SSF69318 70 443 3.53E-52 T 28-03-2018 CNX65_RS14065 7f51132b79d5396eef6ec3e143c002f1 395 Pfam PF07690 Major Facilitator Superfamily 254 390 1.5E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS14065 7f51132b79d5396eef6ec3e143c002f1 395 Gene3D G3DSA:1.20.1250.20 3 196 2.7E-8 T 28-03-2018 CNX65_RS14065 7f51132b79d5396eef6ec3e143c002f1 395 Gene3D G3DSA:1.20.1250.20 205 393 9.6E-24 T 28-03-2018 CNX65_RS14065 7f51132b79d5396eef6ec3e143c002f1 395 SUPERFAMILY SSF103473 10 387 1.14E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS03020 11546d05069e727ad1a8eb46fb63915c 217 SMART SM00855 5 165 1.7E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS03020 11546d05069e727ad1a8eb46fb63915c 217 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 202 2.5E-36 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS03020 11546d05069e727ad1a8eb46fb63915c 217 Gene3D G3DSA:3.40.50.1240 1 209 2.4E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS03020 11546d05069e727ad1a8eb46fb63915c 217 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CNX65_RS03020 11546d05069e727ad1a8eb46fb63915c 217 SUPERFAMILY SSF53254 1 202 8.77E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS18470 4a044a5e9da3dac99c07499a808fb436 288 Gene3D G3DSA:3.40.50.150 41 285 1.3E-39 T 28-03-2018 CNX65_RS18470 4a044a5e9da3dac99c07499a808fb436 288 SUPERFAMILY SSF53335 14 284 1.27E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS18470 4a044a5e9da3dac99c07499a808fb436 288 Pfam PF13649 Methyltransferase domain 94 188 1.3E-15 T 28-03-2018 CNX65_RS19635 33b4e5704ac2392ee4f37ea27dc72d8f 296 Gene3D G3DSA:3.20.20.80 37 294 2.3E-36 T 28-03-2018 CNX65_RS19635 33b4e5704ac2392ee4f37ea27dc72d8f 296 Pfam PF00704 Glycosyl hydrolases family 18 86 226 8.2E-16 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CNX65_RS19635 33b4e5704ac2392ee4f37ea27dc72d8f 296 SUPERFAMILY SSF51445 31 269 5.32E-57 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS19635 33b4e5704ac2392ee4f37ea27dc72d8f 296 ProSitePatterns PS01095 Chitinases family 18 active site. 148 156 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS23550 584d64c756513973680bdac992fda596 450 Gene3D G3DSA:2.60.40.290 361 450 1.2E-13 T 28-03-2018 CNX65_RS23550 584d64c756513973680bdac992fda596 450 Pfam PF00331 Glycosyl hydrolase family 10 39 334 5.1E-107 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS23550 584d64c756513973680bdac992fda596 450 PRINTS PR00134 Glycosyl hydrolase family 10 signature 229 241 6.1E-17 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS23550 584d64c756513973680bdac992fda596 450 PRINTS PR00134 Glycosyl hydrolase family 10 signature 154 165 6.1E-17 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS23550 584d64c756513973680bdac992fda596 450 PRINTS PR00134 Glycosyl hydrolase family 10 signature 199 210 6.1E-17 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS23550 584d64c756513973680bdac992fda596 450 PRINTS PR00134 Glycosyl hydrolase family 10 signature 112 124 6.1E-17 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS23550 584d64c756513973680bdac992fda596 450 Gene3D G3DSA:3.20.20.80 24 348 3.1E-68 T 28-03-2018 CNX65_RS23550 584d64c756513973680bdac992fda596 450 SUPERFAMILY SSF49384 361 450 4.6E-17 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS23550 584d64c756513973680bdac992fda596 450 SUPERFAMILY SSF51445 39 339 1.74E-105 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS23550 584d64c756513973680bdac992fda596 450 SMART SM00637 364 447 2.4E-13 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS23550 584d64c756513973680bdac992fda596 450 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 263 273 - T 28-03-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 CNX65_RS23550 584d64c756513973680bdac992fda596 450 SMART SM00633 81 337 1.1E-127 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS33010 7325733ef7c8cddbc6fa56b8c90e80fb 406 Gene3D G3DSA:2.30.30.410 324 404 0.0037 T 28-03-2018 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 Gene3D G3DSA:2.40.110.10 122 220 9.4E-34 T 28-03-2018 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 Gene3D G3DSA:1.10.540.10 1 121 5.0E-41 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 119 1.4E-37 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 SUPERFAMILY SSF56645 2 246 1.09E-81 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 Gene3D G3DSA:1.20.140.10 221 382 6.9E-59 T 28-03-2018 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 125 137 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 SUPERFAMILY SSF47203 231 381 1.22E-51 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 PIRSF PIRSF016578 132 382 3.1E-9 T 28-03-2018 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 PIRSF PIRSF016578 9 107 8.0E-4 T 28-03-2018 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 221 1.8E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS30655 23c498ec5b11b9d00b1fe74f66e45543 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 1.9E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 Gene3D G3DSA:3.40.1770.10 1 143 7.4E-25 T 28-03-2018 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 Gene3D G3DSA:3.40.1770.10 186 544 6.4E-161 T 28-03-2018 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 Pfam PF17392 Urocanase C-terminal domain 341 535 2.0E-95 T 28-03-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 ProSitePatterns PS01233 Urocanase signature. 431 446 - T 28-03-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 PIRSF PIRSF001423 1 547 4.2E-276 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 Pfam PF17391 Urocanase N-terminal domain 2 128 3.4E-57 T 28-03-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 TIGRFAM TIGR01228 hutU: urocanate hydratase 2 543 1.5E-281 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 SUPERFAMILY SSF111326 2 543 3.79E-247 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 Hamap MF_00577 Urocanate hydratase [hutU]. 1 545 49.668 T 28-03-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30845 d46287c51195fbc9e792b4302cf9800a 548 Pfam PF01175 Urocanase Rossmann-like domain 131 338 1.7E-84 T 28-03-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 SUPERFAMILY SSF100920 359 515 6.28E-60 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 SUPERFAMILY SSF53067 163 357 1.3E-63 T 28-03-2018 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 614 36.361 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 Gene3D G3DSA:3.30.420.40 1 172 2.0E-68 T 28-03-2018 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 Pfam PF00012 Hsp70 protein 77 578 4.0E-218 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 169 182 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 SUPERFAMILY SSF53067 4 161 7.45E-57 T 28-03-2018 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 Gene3D G3DSA:3.30.420.40 173 335 1.0E-48 T 28-03-2018 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 Gene3D G3DSA:2.60.34.10 365 506 7.4E-70 T 28-03-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 308 324 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 115 135 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 444 460 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 31 43 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 363 382 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 175 185 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 PRINTS PR00301 70kDa heat shock protein signature 340 360 3.0E-75 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 311 325 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 Gene3D G3DSA:1.20.1270.10 507 592 1.1E-22 T 28-03-2018 IPR029048 Heat shock protein 70kD, C-terminal domain CNX65_RS34335 db059043afa999fba688bd5c87706ebc 618 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 4 578 7.0E-278 T 28-03-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613 CNX65_RS19225 2b3d55a6a95d823efc832cf17ca45ac8 112 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 4 102 6.8E-20 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS19225 2b3d55a6a95d823efc832cf17ca45ac8 112 Gene3D G3DSA:3.30.750.24 1 107 7.6E-19 T 28-03-2018 IPR002645 STAS domain CNX65_RS19225 2b3d55a6a95d823efc832cf17ca45ac8 112 SUPERFAMILY SSF52091 4 103 1.96E-21 T 28-03-2018 IPR002645 STAS domain CNX65_RS19225 2b3d55a6a95d823efc832cf17ca45ac8 112 Pfam PF13466 STAS domain 18 97 1.2E-18 T 28-03-2018 IPR002645 STAS domain CNX65_RS16405 117683ffd505a2fabaf2143543be4d3d 73 SUPERFAMILY SSF54654 10 73 4.71E-19 T 28-03-2018 IPR000864 Proteinase inhibitor I13, potato inhibitor I GO:0004867|GO:0009611 CNX65_RS16405 117683ffd505a2fabaf2143543be4d3d 73 PRINTS PR00292 Potato inhibitor I signature 38 49 1.1E-9 T 28-03-2018 IPR000864 Proteinase inhibitor I13, potato inhibitor I GO:0004867|GO:0009611 CNX65_RS16405 117683ffd505a2fabaf2143543be4d3d 73 PRINTS PR00292 Potato inhibitor I signature 13 26 1.1E-9 T 28-03-2018 IPR000864 Proteinase inhibitor I13, potato inhibitor I GO:0004867|GO:0009611 CNX65_RS16405 117683ffd505a2fabaf2143543be4d3d 73 PRINTS PR00292 Potato inhibitor I signature 50 60 1.1E-9 T 28-03-2018 IPR000864 Proteinase inhibitor I13, potato inhibitor I GO:0004867|GO:0009611 CNX65_RS16405 117683ffd505a2fabaf2143543be4d3d 73 ProDom PD002604 INHIBITOR PROTEASE PROTEINASE SERINE I DIRECT SEQUENCING PRECURSOR SIGNAL MPI 13 73 3.0E-11 T 28-03-2018 IPR000864 Proteinase inhibitor I13, potato inhibitor I GO:0004867|GO:0009611 CNX65_RS16405 117683ffd505a2fabaf2143543be4d3d 73 Gene3D G3DSA:3.30.10.10 9 73 4.2E-23 T 28-03-2018 CNX65_RS16405 117683ffd505a2fabaf2143543be4d3d 73 Pfam PF00280 Potato inhibitor I family 12 73 1.3E-21 T 28-03-2018 IPR000864 Proteinase inhibitor I13, potato inhibitor I GO:0004867|GO:0009611 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 137 151 8.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 167 8.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 179 8.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 ProSitePatterns PS00622 LuxR-type HTH domain signature. 151 178 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 Pfam PF00072 Response regulator receiver domain 4 115 2.0E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 SMART SM00448 2 115 3.2E-7 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 Gene3D G3DSA:3.40.50.2300 1 124 1.1E-20 T 28-03-2018 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 SUPERFAMILY SSF52172 3 123 1.35E-16 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 SUPERFAMILY SSF46894 125 197 1.94E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 Gene3D G3DSA:1.10.10.10 127 198 9.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 SMART SM00421 134 191 6.1E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32085 ab984709e177f8a97bc0cd66dfc737d6 198 Pfam PF00196 Bacterial regulatory proteins, luxR family 136 189 2.2E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS33990 f45c0b1befda9a8996dcf4211f5839ee 223 SMART SM01211 1 220 5.4E-123 T 28-03-2018 CNX65_RS33990 f45c0b1befda9a8996dcf4211f5839ee 223 SUPERFAMILY SSF52317 1 218 1.81E-71 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS33990 f45c0b1befda9a8996dcf4211f5839ee 223 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 1.7E-81 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33990 f45c0b1befda9a8996dcf4211f5839ee 223 Gene3D G3DSA:3.40.50.880 1 217 8.5E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS33990 f45c0b1befda9a8996dcf4211f5839ee 223 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 205 3.9E-38 T 28-03-2018 CNX65_RS33990 f45c0b1befda9a8996dcf4211f5839ee 223 PIRSF PIRSF001586 1 223 2.5E-79 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33990 f45c0b1befda9a8996dcf4211f5839ee 223 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 38.865 T 28-03-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS23860 7a0619a1d6df0b9c3e339a1c5ca6fe6b 192 SUPERFAMILY SSF46689 2 81 1.3E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23860 7a0619a1d6df0b9c3e339a1c5ca6fe6b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23860 7a0619a1d6df0b9c3e339a1c5ca6fe6b 192 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23860 7a0619a1d6df0b9c3e339a1c5ca6fe6b 192 Gene3D G3DSA:1.10.10.60 2 50 5.4E-17 T 28-03-2018 CNX65_RS23860 7a0619a1d6df0b9c3e339a1c5ca6fe6b 192 Gene3D G3DSA:1.10.10.60 51 139 2.7E-11 T 28-03-2018 CNX65_RS23860 7a0619a1d6df0b9c3e339a1c5ca6fe6b 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 60 4.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10815 def64adff2d937fd0e5fa9f794f68971 408 SUPERFAMILY SSF55931 297 382 3.83E-33 T 28-03-2018 CNX65_RS10815 def64adff2d937fd0e5fa9f794f68971 408 SUPERFAMILY SSF55931 32 261 3.83E-33 T 28-03-2018 CNX65_RS10815 def64adff2d937fd0e5fa9f794f68971 408 Hamap MF_02034 Glutamate--cysteine ligase EgtA [egtA]. 16 407 29.546 T 28-03-2018 IPR017809 Glutamate--cysteine ligase EgtA, Actinobacteria GO:0004357|GO:0052699 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS10815 def64adff2d937fd0e5fa9f794f68971 408 PIRSF PIRSF017901 13 408 1.8E-87 T 28-03-2018 IPR035434 Glutamate--cysteine ligase, bacteria and plant GO:0004357|GO:0006750 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS10815 def64adff2d937fd0e5fa9f794f68971 408 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 77 332 3.4E-48 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS25890 7407a0ccdc03986898ad0ef72d45b70e 285 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 1 284 41.31 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CNX65_RS25890 7407a0ccdc03986898ad0ef72d45b70e 285 Pfam PF03668 P-loop ATPase protein family 1 285 3.8E-109 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CNX65_RS25890 7407a0ccdc03986898ad0ef72d45b70e 285 Gene3D G3DSA:3.40.50.300 2 160 2.4E-12 T 28-03-2018 CNX65_RS25890 7407a0ccdc03986898ad0ef72d45b70e 285 SUPERFAMILY SSF52540 3 154 3.04E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25890 7407a0ccdc03986898ad0ef72d45b70e 285 PIRSF PIRSF005052 1 285 5.6E-112 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 SUPERFAMILY SSF55424 336 409 2.75E-17 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 Gene3D G3DSA:3.50.50.60 26 150 6.9E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 Pfam PF14759 Reductase C-terminal 344 406 3.6E-9 T 28-03-2018 IPR028202 Reductase, C-terminal CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 129 138 2.1E-17 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 18 40 2.1E-17 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 2.1E-17 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 302 2.1E-17 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 2.1E-17 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 Gene3D G3DSA:3.50.50.60 151 200 2.3E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 8.1E-20 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 8.1E-20 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 280 302 8.1E-20 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 30 49 8.1E-20 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 126 144 8.1E-20 T 28-03-2018 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 29 325 1.9E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 SUPERFAMILY SSF51905 28 335 1.51E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 Gene3D G3DSA:3.30.390.30 339 428 4.2E-18 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS14600 e0527a4600a6e23b13124f91459d7f9a 478 Gene3D G3DSA:3.50.50.60 201 335 1.9E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 Gene3D G3DSA:2.60.40.420 109 288 6.3E-41 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 35 247 4.5E-45 T 28-03-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 SUPERFAMILY SSF49503 113 270 1.75E-35 T 28-03-2018 IPR008972 Cupredoxin CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 Gene3D G3DSA:1.10.287.90 25 108 9.3E-19 T 28-03-2018 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 219 236 8.4E-6 T 28-03-2018 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 94 114 8.4E-6 T 28-03-2018 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 PRINTS PR01166 Cytochrome c oxidase subunit II signature 116 135 8.4E-6 T 28-03-2018 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 176 230 - T 28-03-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 26 100 1.2E-4 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 SUPERFAMILY SSF81464 13 110 5.56E-19 T 28-03-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS06765 6cb71a0452e0146c7ea75dbd087bd9b6 300 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 121 236 1.9E-17 T 28-03-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS09035 012ce0bac9e6f2487c33d2cea7c69ba6 238 Gene3D G3DSA:3.40.50.1000 100 238 1.3E-23 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS09035 012ce0bac9e6f2487c33d2cea7c69ba6 238 Gene3D G3DSA:1.10.150.240 23 99 7.2E-21 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CNX65_RS09035 012ce0bac9e6f2487c33d2cea7c69ba6 238 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 9 211 1.5E-51 T 28-03-2018 IPR010976 Beta-phosphoglucomutase hydrolase CNX65_RS09035 012ce0bac9e6f2487c33d2cea7c69ba6 238 Pfam PF00702 haloacid dehalogenase-like hydrolase 9 204 6.5E-16 T 28-03-2018 CNX65_RS09035 012ce0bac9e6f2487c33d2cea7c69ba6 238 SUPERFAMILY SSF56784 9 237 4.58E-38 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS09035 012ce0bac9e6f2487c33d2cea7c69ba6 238 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 99 205 2.3E-12 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:3.40.50.10090 921 1062 0.041 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1430 1445 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Pfam PF00550 Phosphopantetheine attachment site 1406 1471 1.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:3.30.70.250 690 732 3.8E-16 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF51735 901 1105 1.02E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF47336 1400 1482 1.7E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 558 845 1.5E-110 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF52151 554 680 4.71E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF52151 741 834 4.71E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:3.40.47.10 27 297 2.7E-85 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF55048 678 740 1.23E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:3.40.50.720 1115 1371 1.3E-53 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 408 1.8E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1117 1297 2.2E-48 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Pfam PF00698 Acyl transferase domain 557 864 5.6E-80 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:3.40.366.10 554 689 4.1E-40 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SMART SM00825 Beta-ketoacyl synthase 37 461 7.6E-216 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:1.10.1200.10 1372 1483 2.0E-19 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Pfam PF08990 Erythronolide synthase docking 3 27 3.6E-8 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF53901 31 405 1.46E-100 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SMART SM00823 Phosphopantetheine attachment site 1403 1475 1.2E-29 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SMART SM01294 1404 1471 1.8E-6 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF101173 4 35 6.28E-5 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 35 285 2.4E-87 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 SUPERFAMILY SSF51735 1117 1360 1.04E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 411 492 6.5E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Pfam PF08659 KR domain 1118 1295 3.2E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:3.40.366.10 733 851 4.1E-24 T 28-03-2018 CNX65_RS15335 9176c80e2083470648c7f394a8f65037 1552 Gene3D G3DSA:3.40.47.10 300 459 1.9E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 Pfam PF00117 Glutamine amidotransferase class-I 184 364 1.8E-37 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 Gene3D G3DSA:3.50.30.20 1 144 1.1E-62 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00096 Glutamine amidotransferase superfamily signature 222 231 2.2E-11 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00096 Glutamine amidotransferase superfamily signature 341 354 2.2E-11 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00096 Glutamine amidotransferase superfamily signature 250 261 2.2E-11 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 SUPERFAMILY SSF52317 172 368 2.75E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 2 370 44.925 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00097 Anthranilate synthase component II signature 250 261 5.6E-6 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00097 Anthranilate synthase component II signature 222 231 5.6E-6 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00097 Anthranilate synthase component II signature 341 354 5.6E-6 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 367 3.1E-133 T 28-03-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 SUPERFAMILY SSF52021 2 135 2.48E-54 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 Gene3D G3DSA:3.40.50.880 145 370 1.5E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 219 233 8.0E-33 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 180 194 8.0E-33 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 267 284 8.0E-33 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 250 266 8.0E-33 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 292 303 8.0E-33 T 28-03-2018 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 4 130 5.3E-51 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26090 59da9ead2273c5494e8bee0f0c975811 370 SMART SM01097 2 132 6.7E-84 T 28-03-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS17770 5c00569ae98996b8ce8b52c40ccf48c7 249 SUPERFAMILY SSF56300 4 245 6.87E-47 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS17770 5c00569ae98996b8ce8b52c40ccf48c7 249 Hamap MF_00905 3',5'-cyclic adenosine monophosphate phosphodiesterase CpdA [cpdA]. 2 244 32.5 T 28-03-2018 IPR026575 3,5-cyclic adenosine monophosphate phosphodiesterase CpdA GO:0004115 KEGG: 00230+3.1.4.53 CNX65_RS17770 5c00569ae98996b8ce8b52c40ccf48c7 249 Pfam PF00149 Calcineurin-like phosphoesterase 4 189 1.2E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS17770 5c00569ae98996b8ce8b52c40ccf48c7 249 Gene3D G3DSA:3.60.21.10 2 248 1.1E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS07710 a3dc2490ab910fc6740acdaaeca2ce30 232 Gene3D G3DSA:3.30.70.1030 9 129 4.1E-37 T 28-03-2018 CNX65_RS07710 a3dc2490ab910fc6740acdaaeca2ce30 232 Pfam PF06778 Chlorite dismutase 34 221 1.1E-72 T 28-03-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase CNX65_RS07710 a3dc2490ab910fc6740acdaaeca2ce30 232 Gene3D G3DSA:3.30.70.1100 130 229 1.5E-29 T 28-03-2018 CNX65_RS07710 a3dc2490ab910fc6740acdaaeca2ce30 232 SUPERFAMILY SSF54909 5 228 3.75E-73 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 244 394 1.4E-43 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 28 133 1.6E-24 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 PIRSF PIRSF016578 8 380 2.5E-19 T 28-03-2018 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 Gene3D G3DSA:2.40.110.10 139 231 1.1E-32 T 28-03-2018 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 SUPERFAMILY SSF56645 27 243 5.89E-68 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 139 231 3.1E-23 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 SUPERFAMILY SSF47203 243 395 1.55E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 Gene3D G3DSA:1.20.140.10 232 395 1.0E-54 T 28-03-2018 CNX65_RS15910 cd2de563f8d4039cd858f39813913a8f 395 Gene3D G3DSA:1.10.540.10 4 138 1.5E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS04095 3229bbff72028781f98dcc3e7a5714de 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 4.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS04095 3229bbff72028781f98dcc3e7a5714de 214 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 4.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS04095 3229bbff72028781f98dcc3e7a5714de 214 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 75 8.9E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS04095 3229bbff72028781f98dcc3e7a5714de 214 SUPERFAMILY SSF46689 17 98 1.85E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS04095 3229bbff72028781f98dcc3e7a5714de 214 Gene3D G3DSA:1.10.10.60 2 73 2.3E-20 T 28-03-2018 CNX65_RS04095 3229bbff72028781f98dcc3e7a5714de 214 Gene3D G3DSA:1.10.357.10 74 209 1.3E-20 T 28-03-2018 CNX65_RS04095 3229bbff72028781f98dcc3e7a5714de 214 SUPERFAMILY SSF48498 96 207 1.71E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS19310 8c78585e02f2e146febb83fa0bdc0a27 326 SUPERFAMILY SSF52266 28 311 8.99E-57 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS19310 8c78585e02f2e146febb83fa0bdc0a27 326 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 32 302 5.1E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS19310 8c78585e02f2e146febb83fa0bdc0a27 326 Gene3D G3DSA:3.40.50.1110 24 316 2.6E-37 T 28-03-2018 CNX65_RS20945 6378592cf63e9e88e93aed263489cec9 536 SMART SM00283 281 535 1.0E-47 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS20945 6378592cf63e9e88e93aed263489cec9 536 SMART SM00304 221 273 9.5E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS20945 6378592cf63e9e88e93aed263489cec9 536 SUPERFAMILY SSF58104 241 534 6.15E-58 T 28-03-2018 CNX65_RS20945 6378592cf63e9e88e93aed263489cec9 536 Pfam PF00672 HAMP domain 221 256 1.2E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS20945 6378592cf63e9e88e93aed263489cec9 536 Gene3D G3DSA:1.10.287.950 141 322 8.2E-5 T 28-03-2018 CNX65_RS20945 6378592cf63e9e88e93aed263489cec9 536 Gene3D G3DSA:1.10.287.950 323 536 6.1E-45 T 28-03-2018 CNX65_RS20945 6378592cf63e9e88e93aed263489cec9 536 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 341 507 1.4E-28 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 Gene3D G3DSA:3.40.190.10 85 213 5.3E-11 T 28-03-2018 CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 SUPERFAMILY SSF46785 2 83 1.63E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 5.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 5.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 5.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.1E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 SUPERFAMILY SSF53850 102 295 3.26E-11 T 28-03-2018 CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 Pfam PF03466 LysR substrate binding domain 103 295 7.2E-9 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS18430 7fc7bc17191261618c35d182059fb508 309 Gene3D G3DSA:1.10.10.10 1 84 2.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31545 569ced7159c7ff8b8a2a79165d40b9d2 217 Gene3D G3DSA:1.10.10.60 66 85 2.5E-5 T 28-03-2018 CNX65_RS31545 569ced7159c7ff8b8a2a79165d40b9d2 217 Gene3D G3DSA:1.10.357.10 86 216 1.2E-26 T 28-03-2018 CNX65_RS31545 569ced7159c7ff8b8a2a79165d40b9d2 217 Pfam PF13305 WHG domain 107 191 2.9E-14 T 28-03-2018 IPR025996 WHG domain CNX65_RS31545 569ced7159c7ff8b8a2a79165d40b9d2 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 80 4.7E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS31545 569ced7159c7ff8b8a2a79165d40b9d2 217 SUPERFAMILY SSF48498 103 211 5.84E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS31545 569ced7159c7ff8b8a2a79165d40b9d2 217 Gene3D G3DSA:1.10.10.60 16 65 2.4E-11 T 28-03-2018 CNX65_RS31545 569ced7159c7ff8b8a2a79165d40b9d2 217 SUPERFAMILY SSF46689 22 95 4.36E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS06160 364981dca17f591895ef869af75fd24c 304 PIRSF PIRSF002936 4 304 8.1E-133 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CNX65_RS06160 364981dca17f591895ef869af75fd24c 304 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 34 258 6.5E-46 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CNX65_RS06160 364981dca17f591895ef869af75fd24c 304 SUPERFAMILY SSF52402 8 212 3.53E-63 T 28-03-2018 CNX65_RS06160 364981dca17f591895ef869af75fd24c 304 Gene3D G3DSA:3.40.50.620 3 301 4.1E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS06160 364981dca17f591895ef869af75fd24c 304 TIGRFAM TIGR02039 CysD: sulfate adenylyltransferase, small subunit 13 304 1.1E-138 T 28-03-2018 IPR011784 Sulphate adenylyltransferase, small subunit GO:0004781|GO:0019419 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 185 204 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 99 110 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 166 174 1.9E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 4.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 99 110 4.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 176 4.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 4.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 4.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.3E-29 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 54 259 9.4E-30 T 28-03-2018 CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 SUPERFAMILY SSF51735 7 260 1.06E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 Gene3D G3DSA:3.40.50.720 6 191 1.1E-31 T 28-03-2018 CNX65_RS28655 7024d833469890f418d60d07f07dccb4 262 Gene3D G3DSA:3.40.50.720 192 262 1.3E-14 T 28-03-2018 CNX65_RS20970 79f73b685210a06834cc67469d232783 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 4.8E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20970 79f73b685210a06834cc67469d232783 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 4.8E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20970 79f73b685210a06834cc67469d232783 281 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 4.8E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20970 79f73b685210a06834cc67469d232783 281 Pfam PF00561 alpha/beta hydrolase fold 25 122 9.1E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20970 79f73b685210a06834cc67469d232783 281 Gene3D G3DSA:3.40.50.1820 1 277 4.2E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20970 79f73b685210a06834cc67469d232783 281 SUPERFAMILY SSF53474 4 275 9.07E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20970 79f73b685210a06834cc67469d232783 281 PRINTS PR00412 Epoxide hydrolase signature 253 275 8.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20970 79f73b685210a06834cc67469d232783 281 PRINTS PR00412 Epoxide hydrolase signature 30 48 8.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20970 79f73b685210a06834cc67469d232783 281 PRINTS PR00412 Epoxide hydrolase signature 107 120 8.9E-11 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS11730 736a3057017bfe5175f63ba60c12a965 214 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 9 182 2.0E-26 T 28-03-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 CNX65_RS11730 736a3057017bfe5175f63ba60c12a965 214 SUPERFAMILY SSF53335 6 179 4.26E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS11730 736a3057017bfe5175f63ba60c12a965 214 Pfam PF05175 Methyltransferase small domain 15 103 8.1E-11 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CNX65_RS11730 736a3057017bfe5175f63ba60c12a965 214 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 34 48 2.2E-5 T 28-03-2018 CNX65_RS11730 736a3057017bfe5175f63ba60c12a965 214 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 150 174 2.2E-5 T 28-03-2018 CNX65_RS11730 736a3057017bfe5175f63ba60c12a965 214 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 94 106 2.2E-5 T 28-03-2018 CNX65_RS11730 736a3057017bfe5175f63ba60c12a965 214 Gene3D G3DSA:3.40.50.150 5 196 4.3E-29 T 28-03-2018 CNX65_RS10135 145a6d50f9dc61c2a2a12b7a042aaf66 329 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 15 207 7.2E-37 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS10135 145a6d50f9dc61c2a2a12b7a042aaf66 329 SUPERFAMILY SSF56747 11 195 2.55E-27 T 28-03-2018 CNX65_RS10135 145a6d50f9dc61c2a2a12b7a042aaf66 329 SMART SM00943 15 208 1.2E-38 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 Pfam PF00246 Zinc carboxypeptidase 133 411 3.0E-68 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 SUPERFAMILY SSF53187 122 428 9.43E-81 T 28-03-2018 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 ProSitePatterns PS00132 Zinc carboxypeptidases, zinc-binding region 1 signature. 176 198 - T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 256 264 3.2E-12 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 176 190 3.2E-12 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 151 163 3.2E-12 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 PRINTS PR00765 Carboxypeptidase A metalloprotease (M14) family signature 315 328 3.2E-12 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 SMART SM00631 125 415 1.7E-96 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 Gene3D G3DSA:3.40.630.10 122 429 7.8E-71 T 28-03-2018 CNX65_RS28050 3bf911e6efe89362484f8da4f784e560 439 ProSitePatterns PS00133 Zinc carboxypeptidases, zinc-binding region 2 signature. 318 328 - T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS07015 be3bac7c717102b3cbeda7c1b8fb4c85 402 Gene3D G3DSA:1.20.1250.20 218 402 9.3E-16 T 28-03-2018 CNX65_RS07015 be3bac7c717102b3cbeda7c1b8fb4c85 402 Gene3D G3DSA:1.20.1250.20 5 211 5.9E-16 T 28-03-2018 CNX65_RS07015 be3bac7c717102b3cbeda7c1b8fb4c85 402 Pfam PF07690 Major Facilitator Superfamily 39 304 5.9E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS07015 be3bac7c717102b3cbeda7c1b8fb4c85 402 SUPERFAMILY SSF103473 10 401 5.62E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 PRINTS PR00126 ATP synthase gamma subunit signature 75 94 1.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 PRINTS PR00126 ATP synthase gamma subunit signature 282 303 1.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 PRINTS PR00126 ATP synthase gamma subunit signature 251 270 1.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 PRINTS PR00126 ATP synthase gamma subunit signature 182 199 1.3E-34 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 Pfam PF00231 ATP synthase 5 304 6.5E-90 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 304 34.451 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 Gene3D G3DSA:1.10.287.80 196 251 1.1E-20 T 28-03-2018 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 Gene3D G3DSA:3.40.1380.10 64 195 1.4E-39 T 28-03-2018 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 290 303 - T 28-03-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 Gene3D G3DSA:1.10.287.80 252 299 9.1E-12 T 28-03-2018 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 Gene3D G3DSA:1.10.287.80 3 59 2.3E-13 T 28-03-2018 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 304 4.2E-99 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30200 03ef6f84d7f9024c2fcdc73f608cf97c 312 SUPERFAMILY SSF52943 3 304 1.29E-78 T 28-03-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 Pfam PF08245 Mur ligase middle domain 132 319 3.8E-40 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 SUPERFAMILY SSF53623 127 337 6.15E-52 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 SUPERFAMILY SSF53244 341 484 4.4E-35 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 485 31.3 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 Gene3D G3DSA:3.90.190.20 339 490 2.3E-51 T 28-03-2018 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 Pfam PF02875 Mur ligase family, glutamate ligase domain 341 433 1.6E-23 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 Gene3D G3DSA:3.40.1390.10 2 113 1.9E-24 T 28-03-2018 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 Pfam PF01225 Mur ligase family, catalytic domain 29 74 2.8E-8 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 SUPERFAMILY SSF63418 2 77 5.89E-18 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 Gene3D G3DSA:3.40.1190.10 114 335 1.2E-55 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28270 a6b4fdd3b9e3b13d0e33ec4d1c3b8571 490 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 484 9.9E-123 T 28-03-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 SUPERFAMILY SSF51905 4 324 2.11E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 Gene3D G3DSA:3.30.390.30 341 457 1.8E-31 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 311 4.9E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 SUPERFAMILY SSF55424 341 456 4.12E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 Gene3D G3DSA:3.50.50.60 270 340 0.011 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 345 450 7.1E-25 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 253 269 2.8E-23 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 2.8E-23 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.8E-23 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 281 303 2.8E-23 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 2.8E-23 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 Gene3D G3DSA:3.50.50.60 3 150 2.5E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 Gene3D G3DSA:3.50.50.60 151 269 3.0E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PIRSF PIRSF000350 2 455 2.1E-71 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 296 303 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 341 362 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 268 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 406 421 6.1E-56 T 28-03-2018 CNX65_RS06495 db6443ba27eaa4f49ec264f9df59944e 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 428 448 6.1E-56 T 28-03-2018 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 Pfam PF01126 Heme oxygenase 6 205 1.3E-50 T 28-03-2018 IPR016053 Haem oxygenase-like GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 PIRSF PIRSF000343 2 216 9.3E-61 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 SUPERFAMILY SSF48613 5 209 8.39E-56 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 PRINTS PR00088 Haem oxygenase signature 6 31 9.4E-28 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 PRINTS PR00088 Haem oxygenase signature 118 139 9.4E-28 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 PRINTS PR00088 Haem oxygenase signature 41 66 9.4E-28 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 PRINTS PR00088 Haem oxygenase signature 66 91 9.4E-28 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 PRINTS PR00088 Haem oxygenase signature 192 210 9.4E-28 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 PRINTS PR00088 Haem oxygenase signature 160 181 9.4E-28 T 28-03-2018 IPR002051 Haem oxygenase GO:0004392|GO:0006788|GO:0055114 KEGG: 00860+1.14.14.18|MetaCyc: PWY-5874|Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS15555 80ad2f942445b601df6596e41deec1b3 217 Gene3D G3DSA:1.20.910.10 1 217 9.8E-61 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 Pfam PF07729 FCD domain 97 218 1.9E-13 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 SUPERFAMILY SSF48008 93 227 4.45E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 SUPERFAMILY SSF46785 20 104 4.97E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 Gene3D G3DSA:1.20.120.530 96 231 6.3E-22 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 Gene3D G3DSA:1.10.10.10 12 95 2.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 SMART SM00345 29 87 6.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 SMART SM00895 97 220 3.8E-10 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS34575 fec2dcafa2bc3b2623d77a74f3e6b6e6 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 25 87 7.5E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS17840 1023819fdc2ba35b24a574eca25b80a5 228 Gene3D G3DSA:3.40.50.1240 1 206 2.0E-40 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS17840 1023819fdc2ba35b24a574eca25b80a5 228 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 201 5.2E-47 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS17840 1023819fdc2ba35b24a574eca25b80a5 228 TIGRFAM TIGR03848 MSMEG_4193: probable phosphomutase, MSMEG_4193 family 3 205 3.5E-98 T 28-03-2018 IPR022492 Phosphomutase MSMEG4193, putative CNX65_RS17840 1023819fdc2ba35b24a574eca25b80a5 228 SUPERFAMILY SSF53254 3 200 1.56E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS17840 1023819fdc2ba35b24a574eca25b80a5 228 SMART SM00855 3 161 7.0E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 SUPERFAMILY SSF53822 60 323 5.5E-37 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 Gene3D G3DSA:3.40.50.2300 55 174 1.4E-22 T 28-03-2018 CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 Gene3D G3DSA:1.10.260.40 2 54 5.4E-21 T 28-03-2018 CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 SMART SM00354 1 71 2.8E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 47 2.9E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 SUPERFAMILY SSF47413 1 58 7.6E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 Gene3D G3DSA:3.40.50.2300 175 314 9.2E-31 T 28-03-2018 CNX65_RS11070 afdee5938a837dac355618d1d99e50da 337 Pfam PF13377 Periplasmic binding protein-like domain 168 330 6.8E-30 T 28-03-2018 CNX65_RS14860 c27bbb395bdc057cab87476664aec10c 341 Gene3D G3DSA:3.90.25.10 207 336 2.1E-19 T 28-03-2018 CNX65_RS14860 c27bbb395bdc057cab87476664aec10c 341 SUPERFAMILY SSF51735 4 332 2.39E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14860 c27bbb395bdc057cab87476664aec10c 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 255 6.9E-11 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS14860 c27bbb395bdc057cab87476664aec10c 341 Gene3D G3DSA:3.40.50.720 2 206 4.1E-6 T 28-03-2018 CNX65_RS18730 f9e5fb2eb1ade426e8246a097d753308 137 SMART SM00387 38 137 6.9E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18730 f9e5fb2eb1ade426e8246a097d753308 137 SUPERFAMILY SSF55874 25 132 1.16E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18730 f9e5fb2eb1ade426e8246a097d753308 137 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 39 132 4.0E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18730 f9e5fb2eb1ade426e8246a097d753308 137 Gene3D G3DSA:3.30.565.10 10 134 3.2E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS28715 2b9eabcec7ee871e26c241180f3bba6b 501 Gene3D G3DSA:3.40.50.300 277 499 1.0E-43 T 28-03-2018 CNX65_RS28715 2b9eabcec7ee871e26c241180f3bba6b 501 SMART SM00490 307 388 2.8E-31 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS28715 2b9eabcec7ee871e26c241180f3bba6b 501 SUPERFAMILY SSF52540 126 403 1.59E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28715 2b9eabcec7ee871e26c241180f3bba6b 501 Pfam PF00271 Helicase conserved C-terminal domain 290 388 3.5E-25 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS28715 2b9eabcec7ee871e26c241180f3bba6b 501 Gene3D G3DSA:3.40.50.300 6 276 1.7E-51 T 28-03-2018 CNX65_RS28715 2b9eabcec7ee871e26c241180f3bba6b 501 SMART SM00487 73 273 3.7E-51 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS28715 2b9eabcec7ee871e26c241180f3bba6b 501 Pfam PF00270 DEAD/DEAH box helicase 78 247 7.0E-41 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS09745 3eb2dc62ea8b6f7762200fee3970d0d4 132 Gene3D G3DSA:1.10.10.10 3 60 4.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09745 3eb2dc62ea8b6f7762200fee3970d0d4 132 Pfam PF03459 TOBE domain 65 125 6.9E-11 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CNX65_RS09745 3eb2dc62ea8b6f7762200fee3970d0d4 132 Gene3D G3DSA:2.40.50.100 63 128 7.1E-16 T 28-03-2018 CNX65_RS09745 3eb2dc62ea8b6f7762200fee3970d0d4 132 Pfam PF12728 Helix-turn-helix domain 4 52 1.8E-9 T 28-03-2018 CNX65_RS09745 3eb2dc62ea8b6f7762200fee3970d0d4 132 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 4 38 2.9E-10 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CNX65_RS09745 3eb2dc62ea8b6f7762200fee3970d0d4 132 SUPERFAMILY SSF50331 11 127 7.09E-17 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CNX65_RS18160 306c7d0d27065679e58f167b42412346 232 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 204 3.7E-44 T 28-03-2018 IPR002751 Cobalamin (vitamin B12) biosynthesis CbiM family GO:0000041|GO:0016021 CNX65_RS18160 306c7d0d27065679e58f167b42412346 232 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 1 202 3.8E-76 T 28-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CNX65_RS18160 306c7d0d27065679e58f167b42412346 232 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 1 214 26.609 T 28-03-2018 IPR018024 Cobalamin (vitamin B12) biosynthesis protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 CNX65_RS08335 efd7289aee4f8b6ecf63eb33c5e3b708 377 Gene3D G3DSA:1.10.3470.10 14 342 1.3E-22 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS08335 efd7289aee4f8b6ecf63eb33c5e3b708 377 Pfam PF02653 Branched-chain amino acid transport system / permease component 37 327 9.6E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS08335 efd7289aee4f8b6ecf63eb33c5e3b708 377 TIGRFAM TIGR03408 urea_trans_UrtC: urea ABC transporter, permease protein UrtC 27 337 5.6E-123 T 28-03-2018 IPR017778 ABC transporter, urea, permease protein, UrtC CNX65_RS08335 efd7289aee4f8b6ecf63eb33c5e3b708 377 PRINTS PR00342 Rhesus blood group protein signature 172 187 2.3E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CNX65_RS08335 efd7289aee4f8b6ecf63eb33c5e3b708 377 PRINTS PR00342 Rhesus blood group protein signature 111 127 2.3E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CNX65_RS08335 efd7289aee4f8b6ecf63eb33c5e3b708 377 PRINTS PR00342 Rhesus blood group protein signature 15 33 2.3E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CNX65_RS08335 efd7289aee4f8b6ecf63eb33c5e3b708 377 PRINTS PR00342 Rhesus blood group protein signature 289 307 2.3E-5 T 28-03-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 CNX65_RS05615 e474d5d2ed449d3eb7b684a42ac62e34 1782 Gene3D G3DSA:1.25.40.10 188 400 1.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 Gene3D G3DSA:2.60.40.10 279 408 4.9E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 SUPERFAMILY SSF117074 158 233 3.66E-18 T 28-03-2018 CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 SUPERFAMILY SSF117074 55 136 5.1E-16 T 28-03-2018 CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 Pfam PF17210 SdrD B-like domain 57 134 4.1E-12 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 Pfam PF17210 SdrD B-like domain 160 272 5.2E-26 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 284 325 3.6E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 Gene3D G3DSA:2.60.40.10 52 154 5.5E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21655 7cdcc1af7eb1171e7100005a452bf4c1 465 Gene3D G3DSA:2.60.40.10 155 278 1.5E-22 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS31490 be83997fd65a3a00f0727df903a3f72c 328 Gene3D G3DSA:3.40.50.300 52 262 7.9E-37 T 28-03-2018 CNX65_RS31490 be83997fd65a3a00f0727df903a3f72c 328 Gene3D G3DSA:1.10.287.130 264 325 1.4E-20 T 28-03-2018 CNX65_RS31490 be83997fd65a3a00f0727df903a3f72c 328 Gene3D G3DSA:1.20.5.170 1 51 5.3E-22 T 28-03-2018 CNX65_RS31490 be83997fd65a3a00f0727df903a3f72c 328 Pfam PF03308 ArgK protein 22 289 2.5E-111 T 28-03-2018 CNX65_RS31490 be83997fd65a3a00f0727df903a3f72c 328 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 17 323 1.8E-112 T 28-03-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31490 be83997fd65a3a00f0727df903a3f72c 328 SUPERFAMILY SSF52540 4 325 4.98E-92 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16015 115fce8bb6b5dddca523aa5fd94a48df 183 SUPERFAMILY SSF46689 4 71 5.64E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16015 115fce8bb6b5dddca523aa5fd94a48df 183 Pfam PF13305 WHG domain 83 157 2.1E-9 T 28-03-2018 IPR025996 WHG domain CNX65_RS16015 115fce8bb6b5dddca523aa5fd94a48df 183 SUPERFAMILY SSF48498 77 180 1.48E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS16015 115fce8bb6b5dddca523aa5fd94a48df 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 49 7.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16015 115fce8bb6b5dddca523aa5fd94a48df 183 Gene3D G3DSA:1.10.357.10 52 182 1.4E-19 T 28-03-2018 CNX65_RS16015 115fce8bb6b5dddca523aa5fd94a48df 183 Gene3D G3DSA:1.10.10.60 2 51 7.4E-12 T 28-03-2018 CNX65_RS34370 0618deecdf9cf5b439b3705fafd59ba2 280 Gene3D G3DSA:2.60.40.10 32 152 1.2E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS34370 0618deecdf9cf5b439b3705fafd59ba2 280 Pfam PF17210 SdrD B-like domain 35 121 2.0E-13 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS34370 0618deecdf9cf5b439b3705fafd59ba2 280 SUPERFAMILY SSF117074 28 121 7.85E-15 T 28-03-2018 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 Hamap MF_00452 Phosphoenolpyruvate carboxykinase [GTP] [pckG]. 10 603 49.39 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 SUPERFAMILY SSF68923 12 242 8.37E-95 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 PIRSF PIRSF001348 2 603 7.0E-278 T 28-03-2018 IPR008209 Phosphoenolpyruvate carboxykinase, GTP-utilising GO:0004611|GO:0005525|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 ProSitePatterns PS00505 Phosphoenolpyruvate carboxykinase (GTP) signature. 267 275 - T 28-03-2018 IPR018091 Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site GO:0004613 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 Gene3D G3DSA:3.90.228.20 243 315 2.2E-22 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 Gene3D G3DSA:3.90.228.20 324 603 2.3E-123 T 28-03-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 Pfam PF00821 Phosphoenolpyruvate carboxykinase C-terminal P-loop domain 243 602 3.3E-169 T 28-03-2018 IPR035077 Phosphoenolpyruvate carboxykinase, GTP-utilising, C-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 SUPERFAMILY SSF53795 243 602 3.66E-157 T 28-03-2018 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 Gene3D G3DSA:3.40.449.10 6 242 8.2E-109 T 28-03-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 CNX65_RS34560 90264f4d8d37ac9b570db006ea9e376a 603 Pfam PF17297 Phosphoenolpyruvate carboxykinase N-terminal domain 22 239 2.7E-97 T 28-03-2018 IPR035078 Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal GO:0004611|GO:0006094 KEGG: 00010+4.1.1.32|KEGG: 00020+4.1.1.32|KEGG: 00620+4.1.1.32|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 Gene3D G3DSA:3.30.70.20 2 44 3.8E-11 T 28-03-2018 CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 Pfam PF00037 4Fe-4S binding domain 34 56 1.2E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 PRINTS PR00354 7Fe ferredoxin signature 19 29 2.8E-17 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 PRINTS PR00354 7Fe ferredoxin signature 35 52 2.8E-17 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 PRINTS PR00354 7Fe ferredoxin signature 9 19 2.8E-17 T 28-03-2018 IPR000813 7Fe ferredoxin GO:0009055 CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 Gene3D G3DSA:3.30.70.20 45 102 4.9E-9 T 28-03-2018 CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 SUPERFAMILY SSF54862 3 85 1.51E-21 T 28-03-2018 CNX65_RS03800 7574b6af8c8127da0dec8c74a8bc7e59 108 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 40 51 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 Gene3D G3DSA:3.40.50.2300 1 152 2.7E-43 T 28-03-2018 CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 143 1.6E-34 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 2.7E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 46 62 2.7E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 78 93 2.7E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 118 133 2.7E-18 T 28-03-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 SUPERFAMILY SSF52788 1 147 1.2E-38 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS04320 6ad31f42cff4ec0df7758429a44b604b 152 SMART SM00226 2 146 6.3E-42 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS26395 2b1c801100e1e0dc794d2ce5f9cd13be 397 Gene3D G3DSA:3.40.50.450 20 222 2.2E-5 T 28-03-2018 CNX65_RS27625 9d7ec4de924aa3a01c251c4dd3865b05 276 Gene3D G3DSA:2.160.20.80 51 265 1.1E-26 T 28-03-2018 CNX65_RS27625 9d7ec4de924aa3a01c251c4dd3865b05 276 Pfam PF00805 Pentapeptide repeats (8 copies) 200 239 3.6E-14 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS27625 9d7ec4de924aa3a01c251c4dd3865b05 276 SUPERFAMILY SSF141571 177 261 5.49E-22 T 28-03-2018 CNX65_RS27625 9d7ec4de924aa3a01c251c4dd3865b05 276 SUPERFAMILY SSF141571 56 91 5.49E-22 T 28-03-2018 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 Gene3D G3DSA:3.20.20.70 4 467 1.5E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 PIRSF PIRSF000130 3 477 1.1E-137 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 SUPERFAMILY SSF54631 98 201 1.57E-13 T 28-03-2018 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 SMART SM01240 11 473 1.3E-184 T 28-03-2018 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 SUPERFAMILY SSF51412 12 93 3.53E-93 T 28-03-2018 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 SUPERFAMILY SSF51412 201 471 3.53E-93 T 28-03-2018 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 TIGRFAM TIGR01303 IMP_DH_rel_1: IMP dehydrogenase family protein 2 475 2.9E-241 T 28-03-2018 IPR005991 IMP dehydrogenase-related 1 CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 SMART SM00116 98 146 1.9 T 28-03-2018 IPR000644 CBS domain CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 SMART SM00116 157 203 12.0 T 28-03-2018 IPR000644 CBS domain CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 Pfam PF00571 CBS domain 99 138 5.2E-4 T 28-03-2018 IPR000644 CBS domain CNX65_RS03575 51bfae213bd6299e2dbd4871e0fbcfb9 477 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 13 472 4.7E-105 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 SUPERFAMILY SSF55781 41 188 6.54E-20 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 Pfam PF03861 ANTAR domain 190 242 1.9E-15 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 Pfam PF13185 GAF domain 39 176 1.7E-13 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 PIRSF PIRSF036625 6 252 1.1E-56 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 SMART SM00065 38 186 0.0061 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 Gene3D G3DSA:1.10.10.10 193 244 6.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 Gene3D G3DSA:3.30.450.40 10 192 6.4E-25 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 SUPERFAMILY SSF52172 177 242 2.29E-7 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS14140 b780ea9278b4133e9028ece4dfcf2eef 258 SMART SM01012 188 243 1.9E-16 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS12605 2319b5377775a4ad902aee7215d02682 383 Pfam PF00069 Protein kinase domain 11 237 4.9E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS12605 2319b5377775a4ad902aee7215d02682 383 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 108 120 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS12605 2319b5377775a4ad902aee7215d02682 383 PIRSF PIRSF000654 6 237 9.2E-24 T 28-03-2018 CNX65_RS12605 2319b5377775a4ad902aee7215d02682 383 SMART SM00220 1 250 2.0E-37 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS12605 2319b5377775a4ad902aee7215d02682 383 Gene3D G3DSA:1.10.510.10 74 275 2.3E-43 T 28-03-2018 CNX65_RS12605 2319b5377775a4ad902aee7215d02682 383 SUPERFAMILY SSF56112 1 304 1.56E-60 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS12605 2319b5377775a4ad902aee7215d02682 383 Gene3D G3DSA:3.30.200.20 1 73 7.1E-14 T 28-03-2018 CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 SMART SM00279 187 222 1.9E-11 T 28-03-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 179 7.1E-45 T 28-03-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 SUPERFAMILY SSF47807 190 302 1.94E-21 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 188 278 3.9E-20 T 28-03-2018 IPR020045 5'-3' exonuclease, C-terminal domain GO:0003677|GO:0003824 CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 Gene3D G3DSA:3.40.50.1010 3 198 1.5E-52 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 Gene3D G3DSA:1.10.150.20 199 279 3.6E-20 T 28-03-2018 CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 SMART SM00475 3 280 2.8E-76 T 28-03-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 CNX65_RS11490 75a5d43bb240745c532c572ad73a2270 314 SUPERFAMILY SSF88723 3 149 2.85E-36 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 271 447 6.0E-45 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 504 183.874 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 Gene3D G3DSA:3.40.50.880 266 494 5.5E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 17 494 3.1E-139 T 28-03-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 SUPERFAMILY SSF52540 17 253 2.96E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 Gene3D G3DSA:3.40.50.300 14 253 9.2E-53 T 28-03-2018 CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 SUPERFAMILY SSF52317 270 461 4.45E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS28865 c325f5f8ddb8c7b76ae34bb53b1a7526 521 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 17 243 6.8E-24 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 429 199.923 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 132 143 - T 28-03-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 Gene3D G3DSA:3.40.440.10 1 150 1.2E-51 T 28-03-2018 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 Gene3D G3DSA:3.40.440.10 151 265 9.9E-25 T 28-03-2018 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 Gene3D G3DSA:3.90.170.10 266 429 1.3E-69 T 28-03-2018 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 SUPERFAMILY SSF52540 1 427 3.19E-168 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 28-03-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 Pfam PF00709 Adenylosuccinate synthetase 4 422 8.2E-175 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 SMART SM00788 3 423 4.5E-275 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS34135 85dac385a20cf697383d0ecad50e8959 429 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 2.8E-162 T 28-03-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 CNX65_RS28970 ec92226b3e494290aa43e41d1751dd10 325 Pfam PF00248 Aldo/keto reductase family 16 306 5.6E-62 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS28970 ec92226b3e494290aa43e41d1751dd10 325 Gene3D G3DSA:3.20.20.100 1 320 2.1E-70 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS28970 ec92226b3e494290aa43e41d1751dd10 325 SUPERFAMILY SSF51430 7 307 6.81E-75 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 Gene3D G3DSA:1.10.10.60 175 251 1.6E-10 T 28-03-2018 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 SMART SM00342 211 294 3.0E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 SUPERFAMILY SSF51182 20 74 6.52E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 SUPERFAMILY SSF46689 247 294 2.51E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 278 294 7.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 263 278 7.9E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 Gene3D G3DSA:2.60.120.280 26 174 6.1E-14 T 28-03-2018 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 248 290 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 Pfam PF12852 Cupin 2 178 5.3E-26 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 Gene3D G3DSA:1.10.10.60 252 304 5.1E-11 T 28-03-2018 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 Pfam PF12833 Helix-turn-helix domain 217 294 6.8E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22140 ac35ce18557fd80cc8a83d58bb3befea 318 SUPERFAMILY SSF46689 194 245 2.08E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23440 ab4c8dcd548e9a1877f7618e63ceb429 139 Gene3D G3DSA:3.10.450.50 2 136 1.9E-16 T 28-03-2018 CNX65_RS23440 ab4c8dcd548e9a1877f7618e63ceb429 139 Pfam PF12680 SnoaL-like domain 25 123 2.6E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS23440 ab4c8dcd548e9a1877f7618e63ceb429 139 SUPERFAMILY SSF54427 23 134 2.48E-19 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS23790 27490042de28fc915fb2852e0de0f1e5 516 SUPERFAMILY SSF75304 73 514 3.66E-127 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS23790 27490042de28fc915fb2852e0de0f1e5 516 ProSitePatterns PS00571 Amidases signature. 221 252 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CNX65_RS23790 27490042de28fc915fb2852e0de0f1e5 516 Gene3D G3DSA:3.90.1300.10 81 516 9.0E-135 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS23790 27490042de28fc915fb2852e0de0f1e5 516 Pfam PF01425 Amidase 99 506 6.3E-107 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS05465 52eae8a88d69088eddb52523175ecb3f 507 Gene3D G3DSA:3.40.309.10 279 481 5.2E-64 T 28-03-2018 CNX65_RS05465 52eae8a88d69088eddb52523175ecb3f 507 Pfam PF00171 Aldehyde dehydrogenase family 35 494 5.2E-161 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS05465 52eae8a88d69088eddb52523175ecb3f 507 Gene3D G3DSA:3.40.605.10 10 278 2.1E-94 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS05465 52eae8a88d69088eddb52523175ecb3f 507 SUPERFAMILY SSF53720 14 499 3.01E-160 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS05465 52eae8a88d69088eddb52523175ecb3f 507 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 262 269 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS05465 52eae8a88d69088eddb52523175ecb3f 507 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS05395 4830cf61641ea6942c8ddeed19844f22 286 SUPERFAMILY SSF48239 35 138 1.18E-9 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CNX65_RS05395 4830cf61641ea6942c8ddeed19844f22 286 SUPERFAMILY SSF48239 231 282 1.18E-9 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CNX65_RS05395 4830cf61641ea6942c8ddeed19844f22 286 Gene3D G3DSA:1.50.10.20 13 222 1.3E-13 T 28-03-2018 CNX65_RS05395 4830cf61641ea6942c8ddeed19844f22 286 Gene3D G3DSA:1.50.10.20 223 286 0.0013 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF51735 1154 1394 2.6E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF53901 1526 1901 3.19E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF08990 Erythronolide synthase docking 2 27 8.5E-11 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF00698 Acyl transferase domain 549 858 7.5E-55 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF00698 Acyl transferase domain 2055 2320 2.3E-49 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.47.10 1530 1791 6.2E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.50.10090 2461 2582 0.0095 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF55048 673 731 7.59E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 183 199 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF08659 KR domain 2662 2834 2.2E-48 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF08659 KR domain 1156 1331 6.2E-51 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1155 1333 2.0E-42 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2662 2836 5.3E-39 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:1.10.1200.10 1431 1529 3.7E-22 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:1.10.1200.10 2910 3022 6.3E-18 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2056 2336 1.4E-113 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 550 840 4.9E-128 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF53901 31 391 8.36E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.366.10 725 846 1.9E-31 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.366.10 546 683 1.6E-47 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 278 393 1.1E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 1787 1902 2.8E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF47336 2937 3022 4.84E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00825 Beta-ketoacyl synthase 36 447 8.0E-210 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00825 Beta-ketoacyl synthase 1531 1955 2.7E-220 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF52151 725 842 9.16E-77 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF52151 547 668 9.16E-77 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF101173 4 34 5.49E-5 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1529 1779 1.6E-89 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 270 2.8E-82 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF55048 2179 2237 7.19E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF51735 2444 2650 4.72E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 399 514 1.7E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1905 1996 1.5E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 1692 1708 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF52151 2053 2174 3.4E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF52151 2231 2324 3.4E-73 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.47.10 285 445 2.0E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.47.10 1794 1953 1.1E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00823 Phosphopantetheine attachment site 1438 1510 2.3E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM00823 Phosphopantetheine attachment site 2943 3015 1.5E-28 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.366.10 2050 2189 1.8E-51 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF51735 2658 2899 8.2E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.366.10 2232 2335 2.3E-24 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.30.70.250 684 724 1.4E-19 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.30.70.250 2190 2231 1.6E-15 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1465 1480 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF51735 943 1143 1.44E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.50.720 1147 1406 7.2E-52 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.50.720 2654 2909 2.3E-50 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2970 2985 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SUPERFAMILY SSF47336 1433 1543 9.29E-25 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Gene3D G3DSA:3.40.47.10 24 275 3.0E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM01294 2944 3011 4.2E-5 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 SMART SM01294 1439 1506 1.4E-6 T 28-03-2018 CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF00550 Phosphopantetheine attachment site 1440 1506 2.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13580 3202516099a8e05930b138dd2b9470ff 3086 Pfam PF00550 Phosphopantetheine attachment site 2945 3011 1.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS31495 888da049700418408b7e2761999b9945 729 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 39 564 1.4E-274 T 28-03-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31495 888da049700418408b7e2761999b9945 729 SUPERFAMILY SSF52242 562 725 7.33E-58 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS31495 888da049700418408b7e2761999b9945 729 Gene3D G3DSA:3.40.50.280 582 727 2.5E-39 T 28-03-2018 CNX65_RS31495 888da049700418408b7e2761999b9945 729 Pfam PF01642 Methylmalonyl-CoA mutase 40 557 1.5E-231 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31495 888da049700418408b7e2761999b9945 729 Gene3D G3DSA:3.20.20.240 39 559 4.1E-242 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31495 888da049700418408b7e2761999b9945 729 SUPERFAMILY SSF51703 21 559 2.2E-219 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31495 888da049700418408b7e2761999b9945 729 Pfam PF02310 B12 binding domain 599 714 2.9E-14 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS31495 888da049700418408b7e2761999b9945 729 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 382 407 - T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31495 888da049700418408b7e2761999b9945 729 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 596 724 2.1E-61 T 28-03-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 PRINTS PR00364 Disease resistance protein signature 310 325 7.2E-10 T 28-03-2018 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 PRINTS PR00364 Disease resistance protein signature 471 485 7.2E-10 T 28-03-2018 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 PRINTS PR00364 Disease resistance protein signature 387 401 7.2E-10 T 28-03-2018 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 Gene3D G3DSA:3.40.50.300 280 426 2.3E-19 T 28-03-2018 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 Pfam PF00931 NB-ARC domain 297 490 1.5E-12 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 Gene3D G3DSA:1.10.10.10 5 109 3.3E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 Pfam PF00486 Transcriptional regulatory protein, C terminal 37 105 3.0E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 Pfam PF03704 Bacterial transcriptional activator domain 113 256 6.7E-38 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 SMART SM01043 113 257 1.5E-43 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 SUPERFAMILY SSF52540 278 516 3.62E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 SUPERFAMILY SSF48452 109 275 4.74E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 SUPERFAMILY SSF46894 18 106 6.8E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 Gene3D G3DSA:1.25.40.10 111 279 1.4E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS18290 f4e2679afa3fc84cc50400c55db21a9c 707 SMART SM00862 29 106 4.4E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS30710 b5a315fbacbadd34db3ab96c218ff8d7 343 PIRSF PIRSF000443 20 343 3.7E-106 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CNX65_RS30710 b5a315fbacbadd34db3ab96c218ff8d7 343 Pfam PF00561 alpha/beta hydrolase fold 41 325 5.0E-28 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS30710 b5a315fbacbadd34db3ab96c218ff8d7 343 SUPERFAMILY SSF53474 25 337 1.41E-84 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30710 b5a315fbacbadd34db3ab96c218ff8d7 343 TIGRFAM TIGR01392 homoserO_Ac_trn: homoserine O-acetyltransferase 25 337 2.7E-111 T 28-03-2018 IPR008220 Homoserine/serine acetyltransferase MetX-like GO:0005737|GO:0009058|GO:0016747 KEGG: 00270+2.3.1.31|MetaCyc: PWY-5344 CNX65_RS30710 b5a315fbacbadd34db3ab96c218ff8d7 343 Gene3D G3DSA:3.40.50.1820 22 339 2.5E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 Gene3D G3DSA:3.40.1110.10 452 592 8.3E-34 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 201 732 2.8E-145 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 SUPERFAMILY SSF56784 488 729 2.0E-50 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 SUPERFAMILY SSF56784 434 454 2.0E-50 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 Gene3D G3DSA:1.20.1110.10 593 729 4.5E-27 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 SUPERFAMILY SSF55008 12 76 1.57E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 ProSitePatterns PS01047 Heavy-metal-associated domain. 16 44 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 Gene3D G3DSA:1.20.1110.10 93 451 2.1E-41 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00943 Copper-transporting ATPase signature 359 373 7.9E-7 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00943 Copper-transporting ATPase signature 144 163 7.9E-7 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00943 Copper-transporting ATPase signature 663 677 7.9E-7 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00943 Copper-transporting ATPase signature 606 623 7.9E-7 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00943 Copper-transporting ATPase signature 419 434 7.9E-7 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00943 Copper-transporting ATPase signature 26 40 7.9E-7 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 SUPERFAMILY SSF81665 337 428 3.53E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 SUPERFAMILY SSF81665 219 237 3.53E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 Pfam PF00403 Heavy-metal-associated domain 14 72 2.7E-12 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 Gene3D G3DSA:3.30.70.100 10 76 1.6E-19 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 159 731 2.7E-163 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 648 4.5E-27 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 436 450 4.5E-27 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 4.5E-27 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 286 300 4.5E-27 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 664 4.5E-27 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 565 4.5E-27 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 438 444 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 Pfam PF00122 E1-E2 ATPase 237 414 2.3E-52 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 Pfam PF00702 haloacid dehalogenase-like hydrolase 432 643 1.1E-35 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 SUPERFAMILY SSF81653 241 333 1.44E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 206 732 4.3E-111 T 28-03-2018 CNX65_RS14010 5896c8af06ab4ec89a58530c11d84884 739 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 211 714 7.4E-79 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 Gene3D G3DSA:3.90.180.10 1 160 1.6E-32 T 28-03-2018 CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 SMART SM00829 10 317 7.9E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 Gene3D G3DSA:3.40.50.720 161 289 1.6E-16 T 28-03-2018 CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 Pfam PF00107 Zinc-binding dehydrogenase 171 290 8.3E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 83 2.1E-13 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 SUPERFAMILY SSF50129 1 167 3.96E-33 T 28-03-2018 IPR011032 GroES-like CNX65_RS22300 f995894a4a97c60d01fb04cd49447b52 383 SUPERFAMILY SSF51735 135 290 1.89E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30835 aba49332360929ad35b0735484fc30a7 423 SUPERFAMILY SSF51556 50 351 4.66E-65 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS30835 aba49332360929ad35b0735484fc30a7 423 Pfam PF01979 Amidohydrolase family 47 401 8.4E-41 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS30835 aba49332360929ad35b0735484fc30a7 423 Gene3D G3DSA:3.20.20.140 57 372 1.2E-49 T 28-03-2018 CNX65_RS30835 aba49332360929ad35b0735484fc30a7 423 Gene3D G3DSA:2.30.40.10 1 56 0.0029 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS30835 aba49332360929ad35b0735484fc30a7 423 TIGRFAM TIGR02022 hutF: formiminoglutamate deiminase 2 422 2.6E-125 T 28-03-2018 IPR010252 Formiminoglutamate deiminase CNX65_RS30835 aba49332360929ad35b0735484fc30a7 423 SUPERFAMILY SSF51338 337 407 3.56E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS15890 64b36dfe6f6f46c91fc2627c7cd5512d 467 Gene3D G3DSA:3.40.50.980 151 302 1.8E-27 T 28-03-2018 CNX65_RS15890 64b36dfe6f6f46c91fc2627c7cd5512d 467 Pfam PF00501 AMP-binding enzyme 12 377 1.9E-42 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS15890 64b36dfe6f6f46c91fc2627c7cd5512d 467 Gene3D G3DSA:3.40.50.980 1 150 4.8E-15 T 28-03-2018 CNX65_RS15890 64b36dfe6f6f46c91fc2627c7cd5512d 467 Gene3D G3DSA:2.30.38.10 303 371 5.0E-9 T 28-03-2018 CNX65_RS15890 64b36dfe6f6f46c91fc2627c7cd5512d 467 Gene3D G3DSA:3.30.300.30 372 467 1.8E-17 T 28-03-2018 CNX65_RS15890 64b36dfe6f6f46c91fc2627c7cd5512d 467 SUPERFAMILY SSF56801 3 466 1.83E-77 T 28-03-2018 CNX65_RS29810 53854fb4d5b17d173187101ddf14a204 417 Pfam PF13439 Glycosyltransferase Family 4 15 200 5.7E-30 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS29810 53854fb4d5b17d173187101ddf14a204 417 SUPERFAMILY SSF53756 1 396 4.28E-97 T 28-03-2018 CNX65_RS29810 53854fb4d5b17d173187101ddf14a204 417 Gene3D G3DSA:3.40.50.2000 207 382 3.5E-48 T 28-03-2018 CNX65_RS29810 53854fb4d5b17d173187101ddf14a204 417 Gene3D G3DSA:3.40.50.2000 1 206 3.1E-27 T 28-03-2018 CNX65_RS29810 53854fb4d5b17d173187101ddf14a204 417 Pfam PF00534 Glycosyl transferases group 1 216 374 1.3E-39 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 297 304 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Gene3D G3DSA:3.30.470.20 761 964 4.0E-34 T 28-03-2018 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Gene3D G3DSA:3.30.1490.20 661 760 3.2E-25 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Pfam PF02142 MGS-like domain 977 1063 1.6E-19 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SMART SM00851 976 1063 9.3E-32 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Gene3D G3DSA:3.30.470.20 120 402 2.2E-66 T 28-03-2018 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SUPERFAMILY SSF56059 679 954 1.77E-94 T 28-03-2018 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1072 0.0 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 715 729 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SUPERFAMILY SSF48108 396 549 3.4E-41 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Gene3D G3DSA:1.10.1030.10 410 535 9.6E-42 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SUPERFAMILY SSF56059 128 400 5.3E-103 T 28-03-2018 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SUPERFAMILY SSF52335 963 1091 1.05E-35 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Gene3D G3DSA:3.40.50.20 536 660 2.4E-58 T 28-03-2018 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SMART SM01096 421 544 6.5E-59 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 424 544 3.7E-37 T 28-03-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Gene3D G3DSA:3.40.50.1380 965 1095 1.2E-47 T 28-03-2018 IPR011607 Methylglyoxal synthase-like domain CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1084 12.963 T 28-03-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SUPERFAMILY SSF52440 1 127 1.19E-47 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 SUPERFAMILY SSF52440 559 680 3.17E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 679 881 8.3E-35 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 4.9E-68 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 Gene3D G3DSA:3.40.50.20 4 109 4.0E-37 T 28-03-2018 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 4.9E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 4.9E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 4.9E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 4.9E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 4.9E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 4.9E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 4.9E-61 T 28-03-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26085 748270bb09c2095f49c0aa873e556bee 1099 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 844 851 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 Gene3D G3DSA:3.30.300.30 467 601 2.8E-17 T 28-03-2018 CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 Pfam PF00501 AMP-binding enzyme 22 472 2.7E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 Gene3D G3DSA:3.40.50.980 193 392 1.9E-35 T 28-03-2018 CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 Gene3D G3DSA:3.40.50.980 12 192 4.0E-41 T 28-03-2018 CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 SUPERFAMILY SSF56801 342 600 1.44E-107 T 28-03-2018 CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 SUPERFAMILY SSF56801 14 290 1.44E-107 T 28-03-2018 CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 ProSitePatterns PS00455 Putative AMP-binding domain signature. 187 198 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS21865 b1f1d0dbce7a2512b6a1258147b57848 601 Gene3D G3DSA:2.30.38.10 393 465 4.3E-13 T 28-03-2018 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SMART SM00065 168 339 1.5E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Gene3D G3DSA:3.30.565.10 609 762 6.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Gene3D G3DSA:3.30.450.40 151 335 1.4E-39 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SUPERFAMILY SSF55781 153 337 4.17E-55 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 749 762 4.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 725 743 4.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 PRINTS PR00344 Bacterial sensor protein C-terminal signature 691 705 4.8E-10 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Pfam PF00512 His Kinase A (phospho-acceptor) domain 547 612 2.9E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Pfam PF01590 GAF domain 169 334 3.2E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SUPERFAMILY SSF47384 531 611 4.71E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SUPERFAMILY SSF55785 28 140 5.98E-23 T 28-03-2018 IPR000014 PAS domain CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 656 761 1.1E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Pfam PF08446 PAS fold 37 140 9.8E-11 T 28-03-2018 IPR013654 PAS fold-2 GO:0006355 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SUPERFAMILY SSF55874 603 761 1.26E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Gene3D G3DSA:1.10.287.130 535 608 1.3E-9 T 28-03-2018 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SMART SM00387 655 765 4.3E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SUPERFAMILY SSF55781 321 524 2.42E-28 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Gene3D G3DSA:3.30.450.20 23 141 1.7E-18 T 28-03-2018 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 SMART SM00388 545 613 6.5E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS14670 a92301a06773c396b798b8fd879c7d38 768 Pfam PF00360 Phytochrome region 361 529 1.7E-23 T 28-03-2018 IPR013515 Phytochrome, central region GO:0006355|GO:0009584|GO:0018298 CNX65_RS13080 d360bf08fde1aedd767ef087816885a3 504 Gene3D G3DSA:3.40.1580.10 131 316 1.6E-16 T 28-03-2018 CNX65_RS13080 d360bf08fde1aedd767ef087816885a3 504 SMART SM00860 160 302 7.6E-6 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CNX65_RS13080 d360bf08fde1aedd767ef087816885a3 504 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 162 301 1.8E-10 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CNX65_RS13080 d360bf08fde1aedd767ef087816885a3 504 SUPERFAMILY SSF160631 154 207 1.83E-5 T 28-03-2018 CNX65_RS13080 d360bf08fde1aedd767ef087816885a3 504 SUPERFAMILY SSF160631 250 304 1.83E-5 T 28-03-2018 CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 Pfam PF13377 Periplasmic binding protein-like domain 169 326 2.0E-36 T 28-03-2018 CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 SUPERFAMILY SSF53822 63 330 3.34E-65 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 SUPERFAMILY SSF47413 3 61 1.25E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 SMART SM00354 3 73 2.4E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 Gene3D G3DSA:3.40.50.2300 59 173 4.2E-29 T 28-03-2018 CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 1.6E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 Gene3D G3DSA:1.10.260.40 5 58 3.0E-19 T 28-03-2018 CNX65_RS33880 e4a498be5be6820ed7f4b893773c8f65 331 Gene3D G3DSA:3.40.50.2300 174 328 8.3E-39 T 28-03-2018 CNX65_RS04265 3c5613d66607749b9d85e0b917363b3a 462 Gene3D G3DSA:3.30.830.10 255 453 1.6E-26 T 28-03-2018 CNX65_RS04265 3c5613d66607749b9d85e0b917363b3a 462 SUPERFAMILY SSF63411 265 459 6.0E-33 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CNX65_RS04265 3c5613d66607749b9d85e0b917363b3a 462 Pfam PF05193 Peptidase M16 inactive domain 203 377 1.8E-16 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CNX65_RS04265 3c5613d66607749b9d85e0b917363b3a 462 Gene3D G3DSA:3.30.830.10 31 253 2.7E-33 T 28-03-2018 CNX65_RS04265 3c5613d66607749b9d85e0b917363b3a 462 Pfam PF00675 Insulinase (Peptidase family M16) 83 192 3.3E-7 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CNX65_RS04265 3c5613d66607749b9d85e0b917363b3a 462 SUPERFAMILY SSF63411 46 248 4.22E-32 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SUPERFAMILY SSF55874 271 454 3.27E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Gene3D G3DSA:2.40.50.180 480 537 2.8E-10 T 28-03-2018 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Gene3D G3DSA:1.10.287.560 208 269 8.5E-18 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SUPERFAMILY SSF50341 455 590 1.31E-29 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Gene3D G3DSA:1.20.120.160 1 199 1.6E-28 T 28-03-2018 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SMART SM01231 208 268 8.3E-19 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Gene3D G3DSA:3.30.565.10 271 457 6.4E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Gene3D G3DSA:2.40.50.180 584 640 0.27 T 28-03-2018 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Gene3D G3DSA:2.40.50.180 641 710 6.2E-10 T 28-03-2018 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SMART SM00073 1 101 7.9E-19 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SMART SM00387 313 456 5.5E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 315 455 4.9E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SMART SM00260 448 591 1.1E-29 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SMART SM00260 606 742 0.0012 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Gene3D G3DSA:2.30.30.40 538 583 8.1E-18 T 28-03-2018 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Pfam PF01584 CheW-like domain 460 593 4.7E-25 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Pfam PF01584 CheW-like domain 620 740 6.4E-12 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SUPERFAMILY SSF50341 619 739 7.98E-16 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 434 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 440 453 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 410 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 209 268 1.1E-14 T 28-03-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 Pfam PF01627 Hpt domain 7 98 3.7E-14 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SUPERFAMILY SSF47384 209 269 3.92E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS11825 b68ef28ad59c389f4294cca578c0671f 762 SUPERFAMILY SSF47226 4 128 8.9E-26 T 28-03-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160|GO:0004871 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1613 1628 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Pfam PF13193 AMP-binding enzyme C-terminal domain 1473 1565 5.6E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Pfam PF00501 AMP-binding enzyme 1082 1465 2.8E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:3.30.559.10 15 229 8.4E-40 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SMART SM00823 Phosphopantetheine attachment site 538 608 0.095 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SMART SM00823 Phosphopantetheine attachment site 1589 1658 2.3E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:3.40.50.980 1218 1368 4.3E-30 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:2.30.38.10 1376 1458 1.7E-22 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SUPERFAMILY SSF52777 36 205 1.89E-47 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SUPERFAMILY SSF52777 628 799 6.23E-49 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:3.30.559.10 613 812 9.5E-42 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SUPERFAMILY SSF47336 1582 1655 2.09E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Pfam PF00668 Condensation domain 33 460 9.2E-89 T 28-03-2018 IPR001242 Condensation domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Pfam PF00668 Condensation domain 626 1061 3.2E-98 T 28-03-2018 IPR001242 Condensation domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1102 1489 4.3E-115 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SUPERFAMILY SSF52777 810 1053 1.11E-60 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:3.40.50.980 1079 1217 3.7E-39 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SUPERFAMILY SSF47336 531 605 6.67E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:3.30.300.30 517 545 0.62 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:3.30.300.30 1460 1594 1.2E-39 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:1.10.1200.10 242 495 0.28 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SUPERFAMILY SSF52777 213 451 1.67E-50 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 SUPERFAMILY SSF56801 1042 1602 5.1E-142 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Pfam PF00550 Phosphopantetheine attachment site 540 604 7.9E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Pfam PF00550 Phosphopantetheine attachment site 1591 1653 1.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:1.10.1200.10 1595 1671 1.5E-25 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 Gene3D G3DSA:1.10.1200.10 546 612 6.5E-19 T 28-03-2018 CNX65_RS22330 d1c503d8ba7d21f375608541e269b85c 1682 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1216 1227 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 378 3.2E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 Gene3D G3DSA:1.20.140.10 221 388 1.1E-55 T 28-03-2018 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 SUPERFAMILY SSF56645 1 242 3.14E-70 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 208 2.4E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 Gene3D G3DSA:2.40.110.10 125 220 5.3E-34 T 28-03-2018 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 121 9.0E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 SUPERFAMILY SSF47203 227 381 5.48E-53 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 PIRSF PIRSF016578 32 75 5.1 T 28-03-2018 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 PIRSF PIRSF016578 73 101 3.3 T 28-03-2018 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 PIRSF PIRSF016578 232 385 3.9E-8 T 28-03-2018 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 PIRSF PIRSF016578 134 225 0.0011 T 28-03-2018 CNX65_RS07790 2ceaa191bbfa9b3b22928b741b2c5efa 389 Gene3D G3DSA:1.10.540.10 1 124 1.8E-28 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS25690 b4066a49cba9d254a975c3c2b08ba531 107 Gene3D G3DSA:1.10.287.1060 1 100 4.4E-9 T 28-03-2018 CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 SUPERFAMILY SSF51735 4 39 1.44E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 SUPERFAMILY SSF51735 87 248 1.44E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 Gene3D G3DSA:3.40.50.720 1 288 8.0E-38 T 28-03-2018 CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 Pfam PF00106 short chain dehydrogenase 50 231 2.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 228 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 209 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 168 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 29 46 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25645 9a8665637ea838bc366491d47e4d8f22 294 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 108 119 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 TIGRFAM TIGR01137 cysta_beta: cystathionine beta-synthase 5 454 6.9E-201 T 28-03-2018 IPR005857 Cystathionine beta-synthase GO:0004122|GO:0005737|GO:0019343 KEGG: 00260+4.2.1.22|KEGG: 00270+4.2.1.22|MetaCyc: PWY-801 CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 Pfam PF00571 CBS domain 406 454 7.0E-6 T 28-03-2018 IPR000644 CBS domain CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 Pfam PF00571 CBS domain 326 391 4.1E-8 T 28-03-2018 IPR000644 CBS domain CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 SMART SM00116 409 454 0.099 T 28-03-2018 IPR000644 CBS domain CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 SMART SM00116 339 392 7.2E-6 T 28-03-2018 IPR000644 CBS domain CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 SUPERFAMILY SSF54631 325 455 1.39E-19 T 28-03-2018 CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 Gene3D G3DSA:3.40.50.1100 38 145 2.9E-38 T 28-03-2018 CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 Gene3D G3DSA:3.40.50.1100 146 310 4.3E-53 T 28-03-2018 CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 Gene3D G3DSA:3.10.580.10 318 456 4.4E-22 T 28-03-2018 CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 SUPERFAMILY SSF53686 2 317 3.01E-98 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS03485 44bc35760cc81cc87d9f137f971cb009 456 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 296 9.9E-70 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS23830 ff589da39ab54826666fdc4113651cab 297 SUPERFAMILY SSF51735 1 284 5.85E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23830 ff589da39ab54826666fdc4113651cab 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 75 3.4E-10 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS23830 ff589da39ab54826666fdc4113651cab 297 Gene3D G3DSA:3.90.25.10 171 291 1.6E-12 T 28-03-2018 CNX65_RS23830 ff589da39ab54826666fdc4113651cab 297 Gene3D G3DSA:3.40.50.720 1 170 2.3E-19 T 28-03-2018 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 SUPERFAMILY SSF48264 12 394 1.26E-101 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 Pfam PF00067 Cytochrome P450 44 367 8.3E-29 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00385 P450 superfamily signature 269 280 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00385 P450 superfamily signature 234 251 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00385 P450 superfamily signature 346 357 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00385 P450 superfamily signature 337 346 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 133 149 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 150 165 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 346 357 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 316 331 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 269 280 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 86 97 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 188 210 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 337 346 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 PRINTS PR00359 B-class P450 signature 288 315 1.6E-61 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS05955 b058554c7608cab60aedc8db9c2ba97d 394 Gene3D G3DSA:1.10.630.10 1 394 7.4E-84 T 28-03-2018 CNX65_RS17965 8d382bfd7a6a39cd204f28dde0d33192 208 Pfam PF03167 Uracil DNA glycosylase superfamily 98 180 5.5E-6 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS17965 8d382bfd7a6a39cd204f28dde0d33192 208 Gene3D G3DSA:3.40.470.10 9 202 1.7E-16 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS17965 8d382bfd7a6a39cd204f28dde0d33192 208 SUPERFAMILY SSF52141 81 186 2.26E-9 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 SUPERFAMILY SSF52540 218 445 2.05E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Gene3D G3DSA:1.10.8.60 657 735 3.3E-21 T 28-03-2018 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 SUPERFAMILY SSF50692 14 85 9.95E-10 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Gene3D G3DSA:2.40.40.20 2 85 4.7E-14 T 28-03-2018 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 SMART SM00382 251 381 3.1E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 SMART SM00382 506 643 1.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 SMART SM01073 3 87 2.5E-15 T 28-03-2018 IPR003338 CDC48, N-terminal subdomain CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 10 86 6.5E-11 T 28-03-2018 IPR003338 CDC48, N-terminal subdomain CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Gene3D G3DSA:3.40.50.300 212 386 1.9E-21 T 28-03-2018 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Gene3D G3DSA:1.10.8.60 387 458 1.1E-17 T 28-03-2018 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 SUPERFAMILY SSF52540 471 722 1.15E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Gene3D G3DSA:3.40.50.300 459 656 2.0E-54 T 28-03-2018 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 ProSitePatterns PS00674 AAA-protein family signature. 611 629 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 256 378 1.8E-12 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS02190 6d2a59ed0a4d1c543a9ca9d00ff1d932 735 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 510 640 4.8E-40 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 37.653 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 SUPERFAMILY SSF54686 2 137 1.96E-54 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.9E-53 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.6E-47 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 28-03-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.7E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.7E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.7E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.7E-37 T 28-03-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32415 f1cd67f76f28e0568d38f90f1f375da9 139 Gene3D G3DSA:3.90.1170.10 3 139 5.6E-50 T 28-03-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 CNX65_RS03765 19bb31c4e48096532295ad506abb4888 312 SUPERFAMILY SSF161098 96 289 1.83E-30 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03765 19bb31c4e48096532295ad506abb4888 312 Gene3D G3DSA:1.10.3720.10 39 309 4.6E-46 T 28-03-2018 CNX65_RS03765 19bb31c4e48096532295ad506abb4888 312 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 308 7.5E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03765 19bb31c4e48096532295ad506abb4888 312 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 27 77 5.6E-11 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49452 2744 2800 4.32E-11 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 503 537 2.4E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3189 3234 3.9E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2102 2190 1.7E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 1459 1544 8.2E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 1032 1115 2.9E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2534 2610 6.9E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2740 2822 1.1E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 1332 1426 1.29E-17 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.1120 1681 1776 1.9E-15 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 1126 1213 3.92E-15 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 2324 2384 8.1E-11 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 1464 1517 6.8E-11 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 1253 1308 6.3E-10 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 1896 1945 4.4E-10 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 2535 2587 5.8E-12 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 1680 1737 2.3E-11 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 2747 2797 3.5E-12 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 2109 2163 6.9E-9 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 1038 1091 2.0E-11 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF13620 Carboxypeptidase regulatory-like domain 825 884 2.6E-9 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 712 791 1.2E-13 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 1138 1217 4.1E-16 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 598 679 2.8E-13 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 2633 2713 1.7E-13 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 1350 1428 2.4E-18 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 1994 2075 3.7E-12 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 1566 1643 5.8E-17 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 2845 2914 1.1E-15 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 3064 3163 1.3E-33 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 2966 3040 8.8E-16 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 1782 1863 5.9E-18 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 2211 2289 4.6E-16 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 924 1003 3.4E-16 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Pfam PF17210 SdrD B-like domain 2421 2497 3.1E-15 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 2839 2918 8.89E-19 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.1120 1896 1972 4.7E-14 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 1763 1858 8.37E-16 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 2964 3040 3.4E-17 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 2203 2286 8.76E-16 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 2625 2709 1.01E-12 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 592 674 2.62E-13 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 380 494 1.4E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 3173 3313 4.3E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49478 1465 1526 5.1E-13 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 2403 2497 1.44E-12 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49478 2324 2392 2.55E-11 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 689 788 1.44E-15 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49478 2109 2170 1.29E-9 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 1559 1642 6.15E-14 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49478 1681 1743 7.06E-13 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 3057 3150 1.28E-22 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 495 592 1.7E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49464 826 907 4.32E-10 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.1120 1250 1336 6.7E-14 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 1987 2070 4.97E-13 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.1120 823 903 2.5E-12 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.1120 2320 2399 3.2E-15 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49478 1897 1957 2.0E-10 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49452 2534 2591 1.84E-11 T 28-03-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49478 1038 1106 1.92E-11 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 707 810 3.0E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 921 1027 1.4E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 1989 2093 8.0E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 1561 1680 2.0E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 3060 3172 1.3E-24 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 1777 1885 1.7E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 593 704 2.2E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2842 2942 1.2E-23 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2206 2316 3.7E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2963 3059 4.2E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 1345 1456 9.3E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2628 2729 9.0E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 1135 1228 1.8E-19 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 Gene3D G3DSA:2.60.40.10 2416 2533 4.2E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF117074 919 1000 1.44E-15 T 28-03-2018 CNX65_RS12300 f9fcc74f006c0a0d7425a10c0a53eb14 3375 SUPERFAMILY SSF49464 1252 1339 5.89E-12 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CNX65_RS25255 d9a05610cb95e93d544ff1964f9b0dd8 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 95 108 3.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25255 d9a05610cb95e93d544ff1964f9b0dd8 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 3.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25255 d9a05610cb95e93d544ff1964f9b0dd8 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 109 122 3.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25255 d9a05610cb95e93d544ff1964f9b0dd8 260 PRINTS PR00111 Alpha/beta hydrolase fold signature 204 218 3.0E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25255 d9a05610cb95e93d544ff1964f9b0dd8 260 Pfam PF00561 alpha/beta hydrolase fold 27 172 1.4E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25255 d9a05610cb95e93d544ff1964f9b0dd8 260 Gene3D G3DSA:3.40.50.1820 11 257 4.9E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS25255 d9a05610cb95e93d544ff1964f9b0dd8 260 SUPERFAMILY SSF53474 17 257 1.14E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 ProSitePatterns PS00455 Putative AMP-binding domain signature. 162 173 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 Gene3D G3DSA:2.30.38.10 337 422 8.5E-17 T 28-03-2018 CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 SUPERFAMILY SSF56801 5 525 1.7E-102 T 28-03-2018 CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 Gene3D G3DSA:1.10.1200.10 530 624 2.2E-11 T 28-03-2018 CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 Gene3D G3DSA:3.30.300.30 425 522 3.6E-10 T 28-03-2018 CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 Gene3D G3DSA:3.40.50.980 168 336 1.6E-38 T 28-03-2018 CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 SMART SM00823 Phosphopantetheine attachment site 549 615 8.5E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 Gene3D G3DSA:3.40.50.980 2 167 9.8E-30 T 28-03-2018 CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 SUPERFAMILY SSF47336 545 618 1.7E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 Pfam PF00550 Phosphopantetheine attachment site 551 611 1.2E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18340 47e372eff33ffec88731e686a719f3ee 632 Pfam PF00501 AMP-binding enzyme 13 428 4.9E-77 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS15620 8df67ace42c7ea07b462a14c5d3d99ae 437 Gene3D G3DSA:3.90.1150.10 254 436 6.2E-39 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15620 8df67ace42c7ea07b462a14c5d3d99ae 437 Gene3D G3DSA:3.90.1150.10 9 175 3.6E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15620 8df67ace42c7ea07b462a14c5d3d99ae 437 Pfam PF00202 Aminotransferase class-III 23 430 1.8E-81 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15620 8df67ace42c7ea07b462a14c5d3d99ae 437 Gene3D G3DSA:3.90.1150.10 176 253 0.0057 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15620 8df67ace42c7ea07b462a14c5d3d99ae 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 238 275 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15620 8df67ace42c7ea07b462a14c5d3d99ae 437 SUPERFAMILY SSF53383 22 431 7.02E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS33865 ad25b715be93891a750e99e6705d03a2 335 SUPERFAMILY SSF53822 52 326 2.02E-49 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS33865 ad25b715be93891a750e99e6705d03a2 335 Gene3D G3DSA:3.40.50.2300 46 169 2.7E-21 T 28-03-2018 CNX65_RS33865 ad25b715be93891a750e99e6705d03a2 335 Pfam PF13407 Periplasmic binding protein domain 54 298 2.4E-38 T 28-03-2018 IPR025997 Periplasmic binding protein CNX65_RS33865 ad25b715be93891a750e99e6705d03a2 335 Gene3D G3DSA:3.40.50.2300 170 298 6.4E-17 T 28-03-2018 CNX65_RS12670 8413cd6e41eb6c55bfa73e756eeacc21 272 SUPERFAMILY SSF52266 29 254 4.0E-56 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS12670 8413cd6e41eb6c55bfa73e756eeacc21 272 Gene3D G3DSA:3.40.50.1110 24 255 2.0E-37 T 28-03-2018 CNX65_RS12670 8413cd6e41eb6c55bfa73e756eeacc21 272 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 33 254 2.6E-26 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS12200 8fb1771b90b8c1f1ff7da5b2a28978ce 121 Gene3D G3DSA:3.10.290.10 1 99 1.6E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS12200 8fb1771b90b8c1f1ff7da5b2a28978ce 121 SMART SM00363 4 65 6.2E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS12200 8fb1771b90b8c1f1ff7da5b2a28978ce 121 Pfam PF01479 S4 domain 5 50 1.2E-9 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS12200 8fb1771b90b8c1f1ff7da5b2a28978ce 121 SUPERFAMILY SSF55174 3 85 1.7E-20 T 28-03-2018 CNX65_RS12200 8fb1771b90b8c1f1ff7da5b2a28978ce 121 PIRSF PIRSF016821 1 120 3.3E-45 T 28-03-2018 IPR025708 Heat shock protein 15 GO:0003677|GO:0003727|GO:0034605|GO:0043023 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 SUPERFAMILY SSF56645 1 225 3.53E-57 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 Gene3D G3DSA:1.20.140.10 216 378 7.4E-55 T 28-03-2018 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 PIRSF PIRSF016578 7 82 11.0 T 28-03-2018 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 PIRSF PIRSF016578 131 376 5.0E-20 T 28-03-2018 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 SUPERFAMILY SSF47203 227 377 1.93E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 Gene3D G3DSA:1.10.540.10 2 118 8.1E-25 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 Gene3D G3DSA:2.40.110.10 119 215 1.8E-30 T 28-03-2018 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 119 6.5E-23 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 377 1.1E-46 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS21855 3f54bd99b39f6d34df300cc7926c8134 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 216 1.9E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS03235 8f65420c905d0700e0319f35dc508503 189 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 6 189 1.3E-55 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CNX65_RS03235 8f65420c905d0700e0319f35dc508503 189 Pfam PF01195 Peptidyl-tRNA hydrolase 7 189 3.4E-55 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CNX65_RS03235 8f65420c905d0700e0319f35dc508503 189 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 111 121 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CNX65_RS03235 8f65420c905d0700e0319f35dc508503 189 SUPERFAMILY SSF53178 6 189 5.23E-63 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CNX65_RS03235 8f65420c905d0700e0319f35dc508503 189 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 5 182 32.983 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CNX65_RS03235 8f65420c905d0700e0319f35dc508503 189 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 18 31 - T 28-03-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 CNX65_RS03235 8f65420c905d0700e0319f35dc508503 189 Gene3D G3DSA:3.40.50.1470 2 189 1.4E-69 T 28-03-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 CNX65_RS27295 4342ed2b0b54055d7c2e412bcb7914c1 421 Gene3D G3DSA:3.20.20.10 50 298 1.1E-37 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS27295 4342ed2b0b54055d7c2e412bcb7914c1 421 Pfam PF01168 Alanine racemase, N-terminal domain 55 261 1.5E-14 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS27295 4342ed2b0b54055d7c2e412bcb7914c1 421 SMART SM01119 312 409 3.1E-35 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CNX65_RS27295 4342ed2b0b54055d7c2e412bcb7914c1 421 SUPERFAMILY SSF51419 55 268 1.99E-23 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS27295 4342ed2b0b54055d7c2e412bcb7914c1 421 Pfam PF14031 Putative serine dehydratase domain 312 408 3.4E-14 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CNX65_RS13330 499ebc3f367d67beabbbe91a326c1fa8 275 ProSitePatterns PS00211 ABC transporters family signature. 153 167 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS13330 499ebc3f367d67beabbbe91a326c1fa8 275 SUPERFAMILY SSF52540 6 251 5.43E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13330 499ebc3f367d67beabbbe91a326c1fa8 275 SMART SM00382 34 243 1.4E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13330 499ebc3f367d67beabbbe91a326c1fa8 275 Gene3D G3DSA:3.40.50.300 1 250 7.4E-56 T 28-03-2018 CNX65_RS13330 499ebc3f367d67beabbbe91a326c1fa8 275 Pfam PF00005 ABC transporter 25 180 4.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13550 d70b336e4c608221d4786af00a811f73 243 Pfam PF00005 ABC transporter 43 185 2.7E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13550 d70b336e4c608221d4786af00a811f73 243 Gene3D G3DSA:3.40.50.300 23 240 8.1E-34 T 28-03-2018 CNX65_RS13550 d70b336e4c608221d4786af00a811f73 243 SUPERFAMILY SSF52540 27 236 2.51E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13550 d70b336e4c608221d4786af00a811f73 243 SMART SM00382 51 234 3.3E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01860 b006ceaaf5db47dab23fe6ed09319cd1 155 Pfam PF02542 YgbB family 1 151 3.2E-46 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CNX65_RS01860 b006ceaaf5db47dab23fe6ed09319cd1 155 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 1 153 30.062 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CNX65_RS01860 b006ceaaf5db47dab23fe6ed09319cd1 155 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 35 50 - T 28-03-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CNX65_RS01860 b006ceaaf5db47dab23fe6ed09319cd1 155 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 151 6.0E-47 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CNX65_RS01860 b006ceaaf5db47dab23fe6ed09319cd1 155 Gene3D G3DSA:3.30.1330.50 1 154 1.9E-57 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CNX65_RS01860 b006ceaaf5db47dab23fe6ed09319cd1 155 SUPERFAMILY SSF69765 1 152 8.76E-50 T 28-03-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 CNX65_RS31915 53bbcaacf2b6cda238e0c405cd59cffc 211 Pfam PF00551 Formyl transferase 14 193 3.4E-50 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS31915 53bbcaacf2b6cda238e0c405cd59cffc 211 Gene3D G3DSA:3.40.50.170 4 209 9.8E-65 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS31915 53bbcaacf2b6cda238e0c405cd59cffc 211 SUPERFAMILY SSF53328 14 208 6.41E-59 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS31915 53bbcaacf2b6cda238e0c405cd59cffc 211 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 14 199 29.193 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CNX65_RS31915 53bbcaacf2b6cda238e0c405cd59cffc 211 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 13 201 1.8E-67 T 28-03-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1221 1543 1.3E-37 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF47336 1679 1779 3.8E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF00550 Phosphopantetheine attachment site 1686 1737 1.0E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF00550 Phosphopantetheine attachment site 1784 1833 2.6E-4 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2094 2317 1.7E-28 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF51735 2177 2342 1.7E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF51735 2093 2134 1.7E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.20.20.70 303 674 2.0E-20 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.20.20.70 2 195 1.1E-12 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF47336 1776 1872 8.78E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF03060 Nitronate monooxygenase 96 204 6.8E-9 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF03060 Nitronate monooxygenase 323 571 2.0E-7 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SMART SM00825 Beta-ketoacyl synthase 684 1124 4.2E-118 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.40.47.10 961 1122 6.1E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF08659 KR domain 2094 2315 7.9E-36 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF52151 1411 1513 1.96E-55 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF52151 1218 1346 1.96E-55 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:1.10.1200.10 1662 1770 3.0E-16 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.40.366.10 1217 1358 9.6E-31 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.40.366.10 1401 1526 9.1E-28 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 1076 1146 3.6E-7 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 683 946 4.1E-71 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF51412 323 569 6.87E-14 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.40.50.720 2086 2365 5.7E-39 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF00698 Acyl transferase domain 1220 1495 3.3E-40 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.40.47.10 675 957 7.3E-76 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF53901 681 799 1.32E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF53901 842 1067 1.32E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF53901 1100 1121 1.32E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:1.10.1200.10 1779 1867 1.1E-13 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Gene3D G3DSA:3.30.70.250 1359 1400 3.3E-16 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF51412 18 204 2.01E-13 T 28-03-2018 CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 954 1071 5.9E-39 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS12635 3868bf4b20ba5fd746afe50d1482f5e2 2368 SUPERFAMILY SSF55048 1348 1409 1.44E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS18220 f2b004d27b9d06572227094beb506f41 73 Pfam PF03621 MbtH-like protein 2 53 4.7E-28 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS18220 f2b004d27b9d06572227094beb506f41 73 Gene3D G3DSA:3.90.820.10 2 68 2.7E-35 T 28-03-2018 CNX65_RS18220 f2b004d27b9d06572227094beb506f41 73 SMART SM00923 3 53 3.3E-30 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS18220 f2b004d27b9d06572227094beb506f41 73 SUPERFAMILY SSF160582 2 69 1.83E-31 T 28-03-2018 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 SUPERFAMILY SSF48264 60 418 3.54E-84 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 Pfam PF00067 Cytochrome P450 242 392 7.8E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 362 371 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 371 382 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 295 306 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 312 339 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 218 240 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 340 355 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 112 123 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 175 190 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00359 B-class P450 signature 158 174 7.1E-45 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 364 373 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 Gene3D G3DSA:1.10.630.10 47 421 2.3E-68 T 28-03-2018 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00385 P450 superfamily signature 371 382 2.8E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00385 P450 superfamily signature 362 371 2.8E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00385 P450 superfamily signature 260 277 2.8E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10775 6d87513febd1b88b4062d3ae972bcbc3 430 PRINTS PR00385 P450 superfamily signature 295 306 2.8E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 SUPERFAMILY SSF50677 203 342 1.57E-53 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 26 567 7.1E-192 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Gene3D G3DSA:3.90.740.10 197 245 2.9E-13 T 28-03-2018 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 SUPERFAMILY SSF47323 581 823 2.99E-49 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Gene3D G3DSA:3.90.740.10 246 437 1.8E-62 T 28-03-2018 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Gene3D G3DSA:3.40.50.620 438 556 3.3E-40 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Hamap MF_02004 Valine--tRNA ligase [valS]. 13 875 15.096 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 SUPERFAMILY SSF52374 349 578 2.94E-139 T 28-03-2018 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 SUPERFAMILY SSF52374 12 203 2.94E-139 T 28-03-2018 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Gene3D G3DSA:1.10.287.380 803 873 9.2E-21 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 PRINTS PR00986 Valyl-tRNA synthetase signature 47 58 3.2E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 PRINTS PR00986 Valyl-tRNA synthetase signature 239 256 3.2E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 PRINTS PR00986 Valyl-tRNA synthetase signature 479 497 3.2E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 PRINTS PR00986 Valyl-tRNA synthetase signature 354 367 3.2E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 PRINTS PR00986 Valyl-tRNA synthetase signature 448 469 3.2E-37 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Gene3D G3DSA:1.10.730.10 557 720 1.4E-46 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Gene3D G3DSA:3.40.50.620 34 196 6.7E-45 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 54 65 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 TIGRFAM TIGR00422 valS: valine--tRNA ligase 15 852 0.0 T 28-03-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 810 874 7.1E-17 T 28-03-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 Pfam PF08264 Anticodon-binding domain of tRNA 610 751 5.2E-36 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CNX65_RS05805 06536deab8d4c779804cbebd38a4edf1 877 SUPERFAMILY SSF46589 810 874 3.19E-13 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 5 337 1.5E-107 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 Pfam PF14842 FliG N-terminal domain 6 101 2.3E-27 T 28-03-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 7 23 1.3E-62 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 251 271 1.3E-62 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 116 139 1.3E-62 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 275 301 1.3E-62 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 229 249 1.3E-62 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 36 62 1.3E-62 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PRINTS PR00954 Flagellar motor switch protein FliG signature 198 223 1.3E-62 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 Gene3D G3DSA:1.10.220.30 198 337 2.0E-34 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 Gene3D G3DSA:1.10.220.30 85 195 7.6E-20 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 Gene3D G3DSA:1.10.220.30 6 84 4.8E-10 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 Pfam PF01706 FliG C-terminal domain 220 327 5.5E-38 T 28-03-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 PIRSF PIRSF003161 1 337 6.4E-107 T 28-03-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 SUPERFAMILY SSF48029 116 328 2.09E-62 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 SUPERFAMILY SSF48029 6 101 1.83E-18 T 28-03-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical CNX65_RS11945 7bb3c013095a143298312e4a3ae2da3c 338 Pfam PF14841 FliG middle domain 117 189 3.8E-29 T 28-03-2018 IPR032779 Flagellar motor switch protein FliG, middle domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 Gene3D G3DSA:3.30.70.270 273 429 2.1E-39 T 28-03-2018 CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 136 258 8.4E-22 T 28-03-2018 IPR000014 PAS domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 263 419 1.1E-21 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 Gene3D G3DSA:3.30.450.20 133 272 3.0E-28 T 28-03-2018 CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 SUPERFAMILY SSF55073 270 425 4.24E-31 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 SMART SM00086 212 254 2.7E-6 T 28-03-2018 IPR001610 PAC motif CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 Pfam PF00990 Diguanylate cyclase, GGDEF domain 267 417 1.3E-22 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 Gene3D G3DSA:3.20.20.450 430 686 3.4E-55 T 28-03-2018 IPR001633 EAL domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 SMART SM00267 254 423 3.4E-28 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 SUPERFAMILY SSF55785 130 250 1.65E-21 T 28-03-2018 IPR000014 PAS domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 SMART SM00052 433 683 6.5E-26 T 28-03-2018 IPR001633 EAL domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 Pfam PF00563 EAL domain 446 675 1.3E-42 T 28-03-2018 IPR001633 EAL domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 Pfam PF08448 PAS fold 148 255 6.6E-11 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 SMART SM00091 139 205 5.4E-6 T 28-03-2018 IPR000014 PAS domain CNX65_RS30635 2e61cdc4a8107dd46dbeb1b3912cdd5d 694 SUPERFAMILY SSF141868 445 680 1.31E-43 T 28-03-2018 IPR001633 EAL domain CNX65_RS23450 6faee8bdf01e18b0cc1189f457ea23d0 504 Gene3D G3DSA:3.40.50.1820 52 474 8.9E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23450 6faee8bdf01e18b0cc1189f457ea23d0 504 Pfam PF08386 TAP-like protein 390 486 9.4E-26 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS23450 6faee8bdf01e18b0cc1189f457ea23d0 504 SUPERFAMILY SSF53474 183 237 7.78E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23450 6faee8bdf01e18b0cc1189f457ea23d0 504 SUPERFAMILY SSF53474 81 137 7.78E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23450 6faee8bdf01e18b0cc1189f457ea23d0 504 SUPERFAMILY SSF53474 310 474 7.78E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS08740 8f2e489d8cc144785cd5708a8e10a1da 535 SUPERFAMILY SSF56112 12 274 4.05E-64 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS08740 8f2e489d8cc144785cd5708a8e10a1da 535 Gene3D G3DSA:1.10.510.10 98 337 8.8E-43 T 28-03-2018 CNX65_RS08740 8f2e489d8cc144785cd5708a8e10a1da 535 SMART SM00220 15 263 1.8E-42 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS08740 8f2e489d8cc144785cd5708a8e10a1da 535 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 43 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS08740 8f2e489d8cc144785cd5708a8e10a1da 535 Gene3D G3DSA:3.30.200.20 7 97 4.0E-13 T 28-03-2018 CNX65_RS08740 8f2e489d8cc144785cd5708a8e10a1da 535 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 133 145 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS08740 8f2e489d8cc144785cd5708a8e10a1da 535 Pfam PF00069 Protein kinase domain 18 261 2.0E-38 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 SUPERFAMILY SSF52172 175 238 4.12E-5 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 Gene3D G3DSA:1.10.10.10 189 240 1.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 SMART SM01012 184 239 1.1E-14 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 PIRSF PIRSF036625 1 247 4.2E-56 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 SMART SM00065 34 182 2.2E-8 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 SUPERFAMILY SSF55781 37 180 3.05E-21 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 Pfam PF03861 ANTAR domain 186 238 1.0E-13 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 Pfam PF13185 GAF domain 37 172 1.9E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS14145 fdf2245d34edcd0adcef70cfa04add67 258 Gene3D G3DSA:3.30.450.40 6 188 5.3E-26 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14970 a1a37e509f756840fb751ccb0af1a90f 366 SUPERFAMILY SSF51735 4 154 3.16E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14970 a1a37e509f756840fb751ccb0af1a90f 366 Gene3D G3DSA:3.30.360.10 143 350 8.7E-36 T 28-03-2018 CNX65_RS14970 a1a37e509f756840fb751ccb0af1a90f 366 SUPERFAMILY SSF55347 130 292 6.7E-28 T 28-03-2018 CNX65_RS14970 a1a37e509f756840fb751ccb0af1a90f 366 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 7 121 2.0E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS14970 a1a37e509f756840fb751ccb0af1a90f 366 Gene3D G3DSA:3.40.50.720 1 142 2.2E-34 T 28-03-2018 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 SUPERFAMILY SSF55874 7 222 4.88E-52 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 ProSitePatterns PS00177 DNA topoisomerase II signature. 460 468 - T 28-03-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 647 663 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 348 364 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 196 211 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 508 517 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 7 17 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 277 295 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 631 643 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR01159 DNA gyrase subunit B signature 412 432 3.4E-28 T 28-03-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 SMART SM00433 36 671 2.6E-206 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 32 137 5.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 SUPERFAMILY SSF54211 284 428 1.02E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 Pfam PF00204 DNA gyrase B 238 428 7.4E-45 T 28-03-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 Gene3D G3DSA:3.30.230.10 237 432 3.1E-41 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 Pfam PF01751 Toprim domain 457 557 1.5E-12 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 Gene3D G3DSA:3.30.565.10 19 236 8.0E-60 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 524 540 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 71 84 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 114 128 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 458 472 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 610 626 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 303 316 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 562 574 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 542 559 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 PRINTS PR00418 DNA topoisomerase II family signature 36 51 6.7E-58 T 28-03-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 610 666 2.3E-22 T 28-03-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 Gene3D G3DSA:3.40.50.670 438 675 7.8E-77 T 28-03-2018 IPR013759 DNA topoisomerase, type IIA, central domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 SMART SM00387 32 171 2.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11600 c6b2215bee981fd5fd143cddbe196ac9 680 SUPERFAMILY SSF56719 432 668 1.26E-72 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CNX65_RS04785 5b4f9669c64fe8dc82c41807b7ee3eaf 211 SUPERFAMILY SSF102114 46 134 7.06E-7 T 28-03-2018 CNX65_RS04785 5b4f9669c64fe8dc82c41807b7ee3eaf 211 TIGRFAM TIGR04508 queE_Cx14CxxC: 7-carboxy-7-deazaguanine synthase 3 211 5.7E-103 T 28-03-2018 IPR030977 7-carboxy-7-deazaguanine synthase, Cx14CxxC-type GO:0008616|GO:0046872 KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CNX65_RS04785 5b4f9669c64fe8dc82c41807b7ee3eaf 211 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 211 30.803 T 28-03-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 CNX65_RS04785 5b4f9669c64fe8dc82c41807b7ee3eaf 211 Gene3D G3DSA:3.20.20.70 23 197 4.7E-13 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS04785 5b4f9669c64fe8dc82c41807b7ee3eaf 211 Pfam PF04055 Radical SAM superfamily 46 124 3.1E-7 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS17150 086c97736c575c5bd5a9d035d029b337 530 SUPERFAMILY SSF51905 6 186 8.82E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS17150 086c97736c575c5bd5a9d035d029b337 530 SUPERFAMILY SSF51905 440 508 8.82E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS17150 086c97736c575c5bd5a9d035d029b337 530 Gene3D G3DSA:3.50.50.60 1 524 4.5E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS17150 086c97736c575c5bd5a9d035d029b337 530 Pfam PF12831 FAD dependent oxidoreductase 7 510 2.2E-108 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Pfam PF08529 NusA N-terminal domain 66 100 8.8E-7 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Pfam PF08529 NusA N-terminal domain 6 60 9.4E-10 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 SUPERFAMILY SSF54814 180 258 1.63E-26 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 SMART SM00316 110 180 8.1E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 SUPERFAMILY SSF69705 4 99 7.46E-29 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 SUPERFAMILY SSF50249 110 179 1.71E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 1 337 26.541 T 28-03-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 76 323 1.9E-100 T 28-03-2018 IPR010213 Transcription termination factor NusA GO:0003723 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Pfam PF13184 NusA-like KH domain 210 277 2.7E-24 T 28-03-2018 IPR025249 KH domain, NusA-like GO:0003723 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 SMART SM00322 284 337 13.0 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 SMART SM00322 210 283 0.11 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Gene3D G3DSA:2.40.50.140 112 178 5.3E-14 T 28-03-2018 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Gene3D G3DSA:3.30.300.20 179 256 2.7E-31 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Gene3D G3DSA:3.30.300.20 258 329 3.5E-17 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 SUPERFAMILY SSF54814 259 323 2.29E-17 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CNX65_RS28625 1a27bfa90bd817acd9b04f8ea71a1163 337 Gene3D G3DSA:3.30.1480.10 1 99 2.2E-28 T 28-03-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 CNX65_RS29555 ea816e1514cad2511266fdaf0192b9f5 227 SUPERFAMILY SSF56784 1 218 1.38E-42 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS29555 ea816e1514cad2511266fdaf0192b9f5 227 Pfam PF13419 Haloacid dehalogenase-like hydrolase 3 190 7.3E-21 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS29555 ea816e1514cad2511266fdaf0192b9f5 227 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 104 185 3.1E-10 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS29555 ea816e1514cad2511266fdaf0192b9f5 227 Gene3D G3DSA:3.40.50.1000 71 226 7.1E-33 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS29555 ea816e1514cad2511266fdaf0192b9f5 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 134 150 5.5E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS29555 ea816e1514cad2511266fdaf0192b9f5 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 180 193 5.5E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS29555 ea816e1514cad2511266fdaf0192b9f5 227 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 103 116 5.5E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS10265 1eb841d9321c6788b9e41f62b3e9f8b8 661 SUPERFAMILY SSF52540 237 442 1.66E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10265 1eb841d9321c6788b9e41f62b3e9f8b8 661 Gene3D G3DSA:3.40.50.300 189 449 1.7E-14 T 28-03-2018 CNX65_RS32720 1eb841d9321c6788b9e41f62b3e9f8b8 661 SUPERFAMILY SSF52540 237 442 1.66E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32720 1eb841d9321c6788b9e41f62b3e9f8b8 661 Gene3D G3DSA:3.40.50.300 189 449 1.7E-14 T 28-03-2018 CNX65_RS27560 4fe12cf1c286b2333b63f865e6244815 234 SMART SM00382 27 210 5.0E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS27560 4fe12cf1c286b2333b63f865e6244815 234 Gene3D G3DSA:3.40.50.300 1 232 1.7E-55 T 28-03-2018 CNX65_RS27560 4fe12cf1c286b2333b63f865e6244815 234 PIRSF PIRSF039137 1 234 7.8E-107 T 28-03-2018 IPR030660 High-affinity branched-chain amino acid transport ATP-binding protein GO:0015658|GO:0015803 CNX65_RS27560 4fe12cf1c286b2333b63f865e6244815 234 Pfam PF00005 ABC transporter 18 161 2.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS27560 4fe12cf1c286b2333b63f865e6244815 234 SUPERFAMILY SSF52540 2 231 9.02E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27560 4fe12cf1c286b2333b63f865e6244815 234 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS16515 2abc6575833364dc5314bd6eb5e02675 388 Gene3D G3DSA:3.90.1150.10 244 388 2.2E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS16515 2abc6575833364dc5314bd6eb5e02675 388 SUPERFAMILY SSF53383 11 384 3.89E-98 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS16515 2abc6575833364dc5314bd6eb5e02675 388 PIRSF PIRSF000390 3 388 1.5E-122 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS16515 2abc6575833364dc5314bd6eb5e02675 388 Gene3D G3DSA:3.40.640.10 18 243 1.7E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS16515 2abc6575833364dc5314bd6eb5e02675 388 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 20 379 1.0E-118 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS27755 cd0c7280029edd6176b5a6ca8a05f7ec 189 SUPERFAMILY SSF55729 15 166 2.23E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS27755 cd0c7280029edd6176b5a6ca8a05f7ec 189 Gene3D G3DSA:3.40.630.30 4 171 1.6E-25 T 28-03-2018 CNX65_RS27755 cd0c7280029edd6176b5a6ca8a05f7ec 189 Pfam PF00583 Acetyltransferase (GNAT) family 64 153 1.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 SUPERFAMILY SSF46689 63 111 1.52E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 SMART SM00342 27 110 1.2E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 79 94 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 94 110 1.2E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 SUPERFAMILY SSF46689 12 60 3.05E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 Pfam PF12833 Helix-turn-helix domain 33 111 4.3E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 64 106 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 Gene3D G3DSA:1.10.10.60 66 113 9.5E-14 T 28-03-2018 CNX65_RS20620 10bc5eab9e1dc098758b625d5136e029 266 Gene3D G3DSA:1.10.10.60 8 65 1.9E-12 T 28-03-2018 CNX65_RS18060 bba0835be3eb944835e62cefa8701ada 319 Pfam PF00248 Aldo/keto reductase family 16 301 7.1E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS18060 bba0835be3eb944835e62cefa8701ada 319 Gene3D G3DSA:3.20.20.100 1 317 6.2E-99 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS18060 bba0835be3eb944835e62cefa8701ada 319 SUPERFAMILY SSF51430 1 303 2.49E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS02045 bdd01c1dd48dec8f7de137c30f9bb0f7 378 SUPERFAMILY SSF56601 54 370 1.08E-63 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS02045 bdd01c1dd48dec8f7de137c30f9bb0f7 378 Pfam PF00144 Beta-lactamase 49 359 1.7E-53 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS02045 bdd01c1dd48dec8f7de137c30f9bb0f7 378 Gene3D G3DSA:3.40.710.10 43 377 2.8E-64 T 28-03-2018 CNX65_RS09150 a7f95d351d702ac52b4cc4967430446b 284 Pfam PF13560 Helix-turn-helix domain 14 75 3.6E-12 T 28-03-2018 CNX65_RS09150 a7f95d351d702ac52b4cc4967430446b 284 SUPERFAMILY SSF47413 10 69 3.85E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09150 a7f95d351d702ac52b4cc4967430446b 284 Gene3D G3DSA:1.10.260.40 4 203 2.6E-9 T 28-03-2018 CNX65_RS09150 a7f95d351d702ac52b4cc4967430446b 284 SMART SM00530 18 73 0.0034 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS08005 bc929278c1a64858fb797d10ba1c39fc 143 PIRSF PIRSF005028 1 143 1.4E-43 T 28-03-2018 IPR026278 Potassium/proton antiporter subunit KhtT CNX65_RS08005 bc929278c1a64858fb797d10ba1c39fc 143 SUPERFAMILY SSF116726 68 141 2.22E-16 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS08005 bc929278c1a64858fb797d10ba1c39fc 143 Gene3D G3DSA:3.30.70.1450 70 142 2.3E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS08005 bc929278c1a64858fb797d10ba1c39fc 143 Pfam PF02080 TrkA-C domain 72 140 3.2E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00385 P450 superfamily signature 264 281 1.4E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00385 P450 superfamily signature 386 397 1.4E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00385 P450 superfamily signature 304 315 1.4E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00385 P450 superfamily signature 377 386 1.4E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 379 388 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00463 E-class P450 group I signature 343 367 1.6E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00463 E-class P450 group I signature 376 386 1.6E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00463 E-class P450 group I signature 253 270 1.6E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00463 E-class P450 group I signature 41 60 1.6E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 PRINTS PR00463 E-class P450 group I signature 386 409 1.6E-16 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 SUPERFAMILY SSF48264 15 438 7.99E-83 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 Gene3D G3DSA:1.10.630.10 6 440 2.6E-86 T 28-03-2018 CNX65_RS15840 c858dbee065f4c57175865d7f822c6d5 444 Pfam PF00067 Cytochrome P450 16 418 1.0E-52 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12150 7ea8718481e028f1c011254fc005aba1 138 Gene3D G3DSA:3.40.1650.10 1 138 4.6E-28 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CNX65_RS12150 7ea8718481e028f1c011254fc005aba1 138 SUPERFAMILY SSF102546 1 136 1.44E-26 T 28-03-2018 IPR023750 RbsD-like domain GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CNX65_RS12150 7ea8718481e028f1c011254fc005aba1 138 Pfam PF05025 RbsD / FucU transport protein family 1 136 1.6E-28 T 28-03-2018 IPR007721 D-ribose pyranase RbsD/L-fucose mutarotase FucU GO:0005996|GO:0016853|GO:0048029 Reactome: R-HSA-6787639 CNX65_RS18295 e14a1ee58539f0b13707b2b7a34bafc9 104 SUPERFAMILY SSF48600 15 95 6.41E-18 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS18295 e14a1ee58539f0b13707b2b7a34bafc9 104 SMART SM00830 12 92 2.9E-14 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS18295 e14a1ee58539f0b13707b2b7a34bafc9 104 Pfam PF01817 Chorismate mutase type II 12 89 6.2E-14 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS18295 e14a1ee58539f0b13707b2b7a34bafc9 104 Gene3D G3DSA:1.20.59.10 2 101 1.2E-16 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 28.247 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 2 114 5.0E-44 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 21 70 1.0E-19 T 28-03-2018 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 PRINTS PR00062 Ribosomal protein L20 signature 75 101 2.1E-37 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 PRINTS PR00062 Ribosomal protein L20 signature 12 41 2.1E-37 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 PRINTS PR00062 Ribosomal protein L20 signature 42 71 2.1E-37 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 Pfam PF00453 Ribosomal protein L20 3 108 2.2E-44 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 Gene3D G3DSA:1.10.1900.20 56 116 3.1E-26 T 28-03-2018 IPR035566 Ribosomal protein L20 C-terminal domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27250 a0f3f168874d1ff0a127eaf1d4bc0a85 129 SUPERFAMILY SSF74731 3 117 1.57E-45 T 28-03-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS11910 20f7ca06e65c3ff7376227016940f3b4 276 Pfam PF00460 Flagella basal body rod protein 8 35 1.1E-9 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CNX65_RS11910 20f7ca06e65c3ff7376227016940f3b4 276 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 134 7.1E-40 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CNX65_RS11910 20f7ca06e65c3ff7376227016940f3b4 276 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 158 257 1.5E-34 T 28-03-2018 IPR020013 Fagellar hook-basal body protein, FlgE/F/G CNX65_RS11910 20f7ca06e65c3ff7376227016940f3b4 276 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 197 274 1.4E-21 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CNX65_RS11910 20f7ca06e65c3ff7376227016940f3b4 276 SUPERFAMILY SSF117143 91 236 1.2E-39 T 28-03-2018 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 SUPERFAMILY SSF48264 12 396 2.49E-94 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00385 P450 superfamily signature 347 358 1.4E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00385 P450 superfamily signature 271 282 1.4E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00385 P450 superfamily signature 236 253 1.4E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00385 P450 superfamily signature 338 347 1.4E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 140 156 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 271 282 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 194 216 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 317 332 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 338 347 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 93 104 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 347 358 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 157 172 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 PRINTS PR00359 B-class P450 signature 289 316 5.4E-59 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 Gene3D G3DSA:1.10.630.10 2 398 6.3E-78 T 28-03-2018 CNX65_RS06435 a8b335e9bffb9cee0e35b2522fa1f94b 398 Pfam PF00067 Cytochrome P450 87 368 4.6E-26 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS01710 933b2b20f766155ffac12f04ec7a9c9e 282 SUPERFAMILY SSF52540 12 238 4.2E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01710 933b2b20f766155ffac12f04ec7a9c9e 282 Pfam PF00005 ABC transporter 28 175 1.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS01710 933b2b20f766155ffac12f04ec7a9c9e 282 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS01710 933b2b20f766155ffac12f04ec7a9c9e 282 Gene3D G3DSA:3.40.50.300 2 249 2.1E-63 T 28-03-2018 CNX65_RS01710 933b2b20f766155ffac12f04ec7a9c9e 282 SMART SM00382 36 225 4.9E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 SUPERFAMILY SSF46894 148 217 1.63E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 Gene3D G3DSA:1.10.10.10 134 219 9.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 SUPERFAMILY SSF52172 2 133 5.98E-32 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 SMART SM00421 157 214 2.3E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 214 2.5E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 SMART SM00448 2 115 3.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 Gene3D G3DSA:3.40.50.2300 1 133 2.9E-36 T 28-03-2018 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 Pfam PF00072 Response regulator receiver domain 4 116 2.1E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 174 201 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 174 190 6.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 174 6.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16845 2a27273d47af70cb6ecd26cc75f7a3c3 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 190 202 6.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02240 2901764cd459060941c1260220681796 540 Gene3D G3DSA:1.10.560.10 1 180 1.8E-41 T 28-03-2018 IPR027413 GroEL-like equatorial domain CNX65_RS02240 2901764cd459060941c1260220681796 540 Hamap MF_00600 60 kDa chaperonin [groL]. 1 538 41.095 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 Gene3D G3DSA:3.50.7.10 181 371 1.8E-93 T 28-03-2018 IPR027409 GroEL-like apical domain CNX65_RS02240 2901764cd459060941c1260220681796 540 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 SUPERFAMILY SSF48592 6 133 2.66E-72 T 28-03-2018 CNX65_RS02240 2901764cd459060941c1260220681796 540 SUPERFAMILY SSF48592 404 519 2.66E-72 T 28-03-2018 CNX65_RS02240 2901764cd459060941c1260220681796 540 PRINTS PR00298 60kDa chaperonin signature 26 52 2.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 PRINTS PR00298 60kDa chaperonin signature 266 289 2.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 PRINTS PR00298 60kDa chaperonin signature 396 417 2.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 PRINTS PR00298 60kDa chaperonin signature 82 109 2.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 PRINTS PR00298 60kDa chaperonin signature 348 373 2.5E-70 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 523 2.5E-91 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CNX65_RS02240 2901764cd459060941c1260220681796 540 SUPERFAMILY SSF54849 136 199 3.43E-26 T 28-03-2018 CNX65_RS02240 2901764cd459060941c1260220681796 540 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 7.1E-247 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS02240 2901764cd459060941c1260220681796 540 Gene3D G3DSA:1.10.560.10 372 514 1.1E-25 T 28-03-2018 IPR027413 GroEL-like equatorial domain CNX65_RS02240 2901764cd459060941c1260220681796 540 SUPERFAMILY SSF52029 184 374 8.97E-80 T 28-03-2018 IPR027409 GroEL-like apical domain CNX65_RS17780 5c03052f554306833d13809b66539a81 318 SMART SM00079 86 307 0.0012 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CNX65_RS17780 5c03052f554306833d13809b66539a81 318 Gene3D G3DSA:3.40.190.10 75 231 2.5E-37 T 28-03-2018 CNX65_RS17780 5c03052f554306833d13809b66539a81 318 SMART SM00062 86 308 1.4E-66 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS17780 5c03052f554306833d13809b66539a81 318 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 87 306 4.2E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS17780 5c03052f554306833d13809b66539a81 318 SUPERFAMILY SSF53850 76 308 8.69E-61 T 28-03-2018 CNX65_RS17780 5c03052f554306833d13809b66539a81 318 Gene3D G3DSA:3.40.190.10 232 305 7.3E-13 T 28-03-2018 CNX65_RS31235 97b5c4d5a84142e622f9b34f2746edb0 515 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 113 287 3.6E-42 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS31235 97b5c4d5a84142e622f9b34f2746edb0 515 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 394 477 5.1E-11 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CNX65_RS31235 97b5c4d5a84142e622f9b34f2746edb0 515 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 113 287 1.5E-34 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS02370 9a02b41f59d6caa08287cae256ab6364 160 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 7 142 6.6E-29 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02370 9a02b41f59d6caa08287cae256ab6364 160 ProSitePatterns PS01078 Molybdenum cofactor biosynthesis proteins signature 1. 66 79 - T 28-03-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 CNX65_RS02370 9a02b41f59d6caa08287cae256ab6364 160 Pfam PF00994 Probable molybdopterin binding domain 9 143 1.9E-26 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02370 9a02b41f59d6caa08287cae256ab6364 160 SUPERFAMILY SSF53218 7 154 1.31E-39 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02370 9a02b41f59d6caa08287cae256ab6364 160 SMART SM00852 8 150 3.3E-20 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS02370 9a02b41f59d6caa08287cae256ab6364 160 Gene3D G3DSA:3.40.980.10 1 151 2.7E-35 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 Gene3D G3DSA:1.10.10.10 1061 1112 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 SUPERFAMILY SSF52540 8 110 1.11E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 Gene3D G3DSA:3.40.50.300 2 146 0.0011 T 28-03-2018 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 SUPERFAMILY SSF46894 1046 1106 5.44E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 Pfam PF00196 Bacterial regulatory proteins, luxR family 1055 1105 7.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 Gene3D G3DSA:1.25.40.10 713 872 0.016 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 Gene3D G3DSA:1.25.40.10 873 1060 3.3E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1069 1096 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1069 1085 8.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1085 1097 8.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1055 1069 8.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16140 cefeb6e9c6d9a5a89f209fd847565e10 1117 SMART SM00421 1052 1109 1.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 Pfam PF00175 Oxidoreductase NAD-binding domain 244 345 2.8E-18 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 SUPERFAMILY SSF63380 138 232 5.38E-24 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 SUPERFAMILY SSF52343 237 365 1.44E-31 T 28-03-2018 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 Gene3D G3DSA:3.40.50.80 231 364 3.2E-22 T 28-03-2018 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 Pfam PF00970 Oxidoreductase FAD-binding domain 140 232 4.9E-16 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 Gene3D G3DSA:2.40.30.10 133 230 6.3E-20 T 28-03-2018 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 183 190 2.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 165 175 2.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 243 262 2.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 332 340 2.2E-7 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 Gene3D G3DSA:1.10.490.10 1 132 3.1E-32 T 28-03-2018 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 Pfam PF00042 Globin 3 95 8.3E-9 T 28-03-2018 IPR000971 Globin GO:0020037 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 243 262 7.7E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 332 340 7.7E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 165 177 7.7E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 PRINTS PR00410 Phenol hydroxylase reductase family signature 268 277 7.7E-12 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CNX65_RS34315 9192c54f6784d810647103cd48a08553 367 SUPERFAMILY SSF46458 3 128 5.17E-33 T 28-03-2018 IPR009050 Globin-like CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 SMART SM00347 50 153 2.6E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 77 93 2.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 109 2.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 129 2.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 PRINTS PR00598 Bacterial regulatory protein MarR family signature 143 163 2.7E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 SUPERFAMILY SSF46785 19 167 6.5E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 Gene3D G3DSA:1.10.10.10 6 168 8.4E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 Pfam PF12802 MarR family 57 117 1.4E-12 T 28-03-2018 CNX65_RS12445 e8be7d11a45c4dc07368a1de3b449658 168 ProSitePatterns PS01117 MarR-type HTH domain signature. 92 126 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CNX65_RS04035 ea051fa797acaebffd99f5b5534bc221 355 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 8 353 1.8E-102 T 28-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 CNX65_RS10600 2d96e9e02c00281aad3874d4b358d5ff 471 PIRSF PIRSF006060 9 469 7.1E-66 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS10600 2d96e9e02c00281aad3874d4b358d5ff 471 Pfam PF13520 Amino acid permease 34 429 1.6E-38 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS10600 2d96e9e02c00281aad3874d4b358d5ff 471 TIGRFAM TIGR00908 2A0305: ethanolamine permease 17 459 2.2E-161 T 28-03-2018 IPR004757 Ethanolamine permease CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 SMART SM00823 Phosphopantetheine attachment site 520 588 7.3E-12 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Pfam PF00550 Phosphopantetheine attachment site 525 584 1.7E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 SUPERFAMILY SSF47336 519 586 2.36E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Gene3D G3DSA:2.30.38.10 294 391 1.0E-10 T 28-03-2018 CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 SUPERFAMILY SSF56801 13 491 1.26E-111 T 28-03-2018 CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Pfam PF00501 AMP-binding enzyme 18 398 1.9E-67 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 ProSitePatterns PS00455 Putative AMP-binding domain signature. 145 156 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Gene3D G3DSA:3.30.300.30 392 493 2.7E-25 T 28-03-2018 CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Gene3D G3DSA:3.40.50.980 151 293 5.8E-37 T 28-03-2018 CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Pfam PF13193 AMP-binding enzyme C-terminal domain 406 479 8.2E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Gene3D G3DSA:1.10.1200.10 503 588 1.3E-17 T 28-03-2018 CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 ProSitePatterns PS00012 Phosphopantetheine attachment site. 543 558 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS22430 9b6571bb6dee9135dfe9c95c20b7d337 588 Gene3D G3DSA:3.40.50.980 12 150 1.7E-30 T 28-03-2018 CNX65_RS20915 67ea6940a81205aafb376a4d62fb208b 314 SMART SM00829 10 312 6.0E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS20915 67ea6940a81205aafb376a4d62fb208b 314 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 103 6.8E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS20915 67ea6940a81205aafb376a4d62fb208b 314 Gene3D G3DSA:3.90.180.10 1 314 3.5E-55 T 28-03-2018 CNX65_RS20915 67ea6940a81205aafb376a4d62fb208b 314 SUPERFAMILY SSF50129 1 162 1.1E-26 T 28-03-2018 IPR011032 GroES-like CNX65_RS20915 67ea6940a81205aafb376a4d62fb208b 314 SUPERFAMILY SSF51735 129 311 2.02E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20915 67ea6940a81205aafb376a4d62fb208b 314 Pfam PF13602 Zinc-binding dehydrogenase 211 312 3.5E-13 T 28-03-2018 CNX65_RS28485 5aea001c29f1e88ed60403b3d3367bf5 185 Pfam PF05534 HicB family 92 135 4.7E-7 T 28-03-2018 IPR008651 Uncharacterised protein family HicB CNX65_RS28485 5aea001c29f1e88ed60403b3d3367bf5 185 SUPERFAMILY SSF47598 100 144 9.45E-9 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CNX65_RS28485 5aea001c29f1e88ed60403b3d3367bf5 185 Gene3D G3DSA:1.10.1220.10 102 139 3.3E-9 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CNX65_RS32320 ec59a10579d3e79b59a5edb631666073 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 2 37 5.1E-21 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32320 ec59a10579d3e79b59a5edb631666073 37 SUPERFAMILY SSF57840 2 37 2.62E-15 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32320 ec59a10579d3e79b59a5edb631666073 37 Pfam PF00444 Ribosomal protein L36 2 37 9.5E-17 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32320 ec59a10579d3e79b59a5edb631666073 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 16.329 T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32320 ec59a10579d3e79b59a5edb631666073 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 28-03-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32320 ec59a10579d3e79b59a5edb631666073 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 9 37 2.0E-9 T 28-03-2018 CNX65_RS27410 da93253792d73746d98bb4eb571da664 185 SUPERFAMILY SSF82607 23 102 2.88E-6 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS27410 da93253792d73746d98bb4eb571da664 185 Gene3D G3DSA:3.30.1310.10 12 112 8.2E-14 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS27410 da93253792d73746d98bb4eb571da664 185 Pfam PF02575 YbaB/EbfC DNA-binding family 21 102 4.1E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS11305 970dc0e93abdf18d3b564d0ccdbbcdf4 255 SUPERFAMILY SSF54637 113 253 3.33E-8 T 28-03-2018 IPR029069 HotDog domain CNX65_RS11305 970dc0e93abdf18d3b564d0ccdbbcdf4 255 Gene3D G3DSA:3.10.129.10 15 106 1.1E-4 T 28-03-2018 CNX65_RS11305 970dc0e93abdf18d3b564d0ccdbbcdf4 255 Pfam PF13622 Thioesterase-like superfamily 20 252 1.0E-33 T 28-03-2018 CNX65_RS11305 970dc0e93abdf18d3b564d0ccdbbcdf4 255 Gene3D G3DSA:3.10.129.10 175 254 0.14 T 28-03-2018 CNX65_RS06890 145dffa333517ccc0d9fc3f3c86a141d 245 Gene3D G3DSA:3.40.1130.10 1 231 3.1E-55 T 28-03-2018 CNX65_RS06890 145dffa333517ccc0d9fc3f3c86a141d 245 SMART SM00563 36 155 1.8E-32 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS06890 145dffa333517ccc0d9fc3f3c86a141d 245 SUPERFAMILY SSF69593 4 223 2.48E-51 T 28-03-2018 CNX65_RS06890 145dffa333517ccc0d9fc3f3c86a141d 245 Pfam PF01553 Acyltransferase 24 152 2.2E-22 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 Pfam PF00108 Thiolase, N-terminal domain 6 264 6.8E-97 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 85 103 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 SUPERFAMILY SSF53901 6 271 1.87E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 PIRSF PIRSF000429 2 395 9.6E-116 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 ProSitePatterns PS00099 Thiolases active site. 375 388 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 Pfam PF02803 Thiolase, C-terminal domain 272 392 5.5E-41 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 SUPERFAMILY SSF53901 273 392 2.02E-35 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 7 391 1.1E-131 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 Gene3D G3DSA:3.40.47.10 151 266 3.4E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 Gene3D G3DSA:3.40.47.10 2 150 5.9E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 ProSitePatterns PS00737 Thiolases signature 2. 340 356 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CNX65_RS30030 72f94f924a2c7b33989e5765ff29a214 397 Gene3D G3DSA:3.40.47.10 267 391 1.1E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 Gene3D G3DSA:3.40.50.300 3 243 6.3E-68 T 28-03-2018 CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 Pfam PF08402 TOBE domain 282 352 4.1E-6 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 SUPERFAMILY SSF50331 239 364 3.68E-21 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 Pfam PF00005 ABC transporter 23 164 5.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 Gene3D G3DSA:2.40.50.140 288 347 1.8E-16 T 28-03-2018 CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 Gene3D G3DSA:2.40.50.100 244 287 9.7E-8 T 28-03-2018 CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 SMART SM00382 31 214 4.8E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01800 3d2e7f2380a6165393804fb57b7b1927 366 SUPERFAMILY SSF52540 12 245 4.17E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 6 324 1.3E-123 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 Gene3D G3DSA:3.30.420.40 150 301 8.1E-18 T 28-03-2018 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 138 150 1.1E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 7 20 1.1E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 162 183 1.1E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 83 103 1.1E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 275 284 1.1E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 104 123 1.1E-50 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 Gene3D G3DSA:3.30.420.40 4 149 1.1E-35 T 28-03-2018 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 4 344 59.725 T 28-03-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 ProSitePatterns PS01016 Glycoprotease family signature. 103 123 - T 28-03-2018 IPR017860 Peptidase M22, conserved site KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618|Reactome: R-HSA-6782315 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 Pfam PF00814 Glycoprotease family 30 318 1.3E-95 T 28-03-2018 IPR000905 Gcp-like domain KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 SUPERFAMILY SSF53067 5 320 4.81E-37 T 28-03-2018 CNX65_RS32120 84ab4bc28435fe81d4c8ab683fd29756 350 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 7 318 3.4E-94 T 28-03-2018 IPR017861 Kae1/TsaD family KEGG: 00564+2.3.1.23|MetaCyc: PWY-5353|MetaCyc: PWY-5368|MetaCyc: PWY-5995|MetaCyc: PWY-6433|MetaCyc: PWY-6803|MetaCyc: PWY-6958|MetaCyc: PWY-7053|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7470|MetaCyc: PWY-7618 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 ProSitePatterns PS00938 Initiation factor 3 signature. 68 81 - T 28-03-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 SUPERFAMILY SSF54364 15 88 1.7E-28 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 5 180 29.68 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 17 179 1.5E-61 T 28-03-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 94 177 9.2E-34 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 17 85 4.1E-30 T 28-03-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 SUPERFAMILY SSF55200 95 179 3.27E-30 T 28-03-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 Gene3D G3DSA:3.10.20.80 12 88 2.6E-32 T 28-03-2018 CNX65_RS27260 1503521e8a33fda1a00b3f585a659624 204 Gene3D G3DSA:3.30.110.10 89 188 1.9E-32 T 28-03-2018 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 SUPERFAMILY SSF47413 5 60 3.28E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 Gene3D G3DSA:1.10.260.40 5 60 2.9E-18 T 28-03-2018 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 Pfam PF13377 Periplasmic binding protein-like domain 171 334 2.5E-37 T 28-03-2018 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 Gene3D G3DSA:3.40.50.2300 61 169 3.2E-31 T 28-03-2018 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 SUPERFAMILY SSF53822 64 334 7.25E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 Gene3D G3DSA:3.40.50.2300 170 337 6.0E-51 T 28-03-2018 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 6 51 5.8E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 7 25 - T 28-03-2018 CNX65_RS04900 bfccf4888ef3336f0b25a492336228ca 338 SMART SM00354 4 74 8.1E-21 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS34125 cbc5b467928e4a70cdab0e6b910b1eae 365 SUPERFAMILY SSF51695 36 362 1.02E-80 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS34125 cbc5b467928e4a70cdab0e6b910b1eae 365 Gene3D G3DSA:3.20.20.190 23 365 5.6E-74 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS34125 cbc5b467928e4a70cdab0e6b910b1eae 365 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 42 357 3.0E-52 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CNX65_RS35025 4262a60548615320a6f807d43f451dbf 210 Pfam PF08445 FR47-like protein 98 134 2.3E-5 T 28-03-2018 IPR013653 FR47-like GO:0016747 CNX65_RS35025 4262a60548615320a6f807d43f451dbf 210 SUPERFAMILY SSF55729 39 168 2.88E-10 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS35025 4262a60548615320a6f807d43f451dbf 210 Gene3D G3DSA:3.40.630.30 13 199 6.6E-17 T 28-03-2018 CNX65_RS26565 c3dd712ad4cf7165ad6d501541bb70ba 186 Gene3D G3DSA:3.40.50.1820 1 184 1.1E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS26565 c3dd712ad4cf7165ad6d501541bb70ba 186 SUPERFAMILY SSF53474 16 180 3.62E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30855 db5918d112cc251f97666b4b8aec60ae 259 SUPERFAMILY SSF46785 7 80 2.52E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30855 db5918d112cc251f97666b4b8aec60ae 259 SMART SM00346 7 97 2.4E-20 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS30855 db5918d112cc251f97666b4b8aec60ae 259 Pfam PF09339 IclR helix-turn-helix domain 9 56 2.2E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS30855 db5918d112cc251f97666b4b8aec60ae 259 Pfam PF01614 Bacterial transcriptional regulator 126 227 4.0E-20 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS30855 db5918d112cc251f97666b4b8aec60ae 259 SUPERFAMILY SSF55781 72 255 3.4E-42 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS30855 db5918d112cc251f97666b4b8aec60ae 259 Gene3D G3DSA:1.10.10.10 3 76 2.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30855 db5918d112cc251f97666b4b8aec60ae 259 Gene3D G3DSA:3.30.450.40 77 259 7.4E-50 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 Gene3D G3DSA:3.20.20.40 177 605 2.6E-135 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 PRINTS PR00733 Glycosyl hydrolase family 6 signature 196 215 4.7E-27 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 PRINTS PR00733 Glycosyl hydrolase family 6 signature 531 545 4.7E-27 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 PRINTS PR00733 Glycosyl hydrolase family 6 signature 508 528 4.7E-27 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 PRINTS PR00733 Glycosyl hydrolase family 6 signature 357 370 4.7E-27 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 PRINTS PR00733 Glycosyl hydrolase family 6 signature 285 300 4.7E-27 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 PRINTS PR00733 Glycosyl hydrolase family 6 signature 467 480 4.7E-27 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 Pfam PF00553 Cellulose binding domain 42 142 8.0E-27 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 Gene3D G3DSA:2.60.40.290 33 142 1.9E-33 T 28-03-2018 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 SUPERFAMILY SSF51989 177 605 1.83E-94 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 PIRSF PIRSF001100 14 605 9.9E-110 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 258 274 - T 28-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 Pfam PF01341 Glycosyl hydrolases family 6 199 554 1.2E-87 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 SMART SM00637 42 142 3.7E-38 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS11175 fd11b26534b3e26f80e21005ff2b28a5 605 SUPERFAMILY SSF49384 39 143 1.4E-28 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 72 2.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 38 69 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 SUPERFAMILY SSF48498 93 171 1.42E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 Gene3D G3DSA:1.10.357.10 71 204 1.8E-14 T 28-03-2018 CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 47 70 1.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 1.8E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 Gene3D G3DSA:1.10.10.60 2 70 1.8E-22 T 28-03-2018 CNX65_RS22240 0602306e3674629fa1ed7c09dfc076bc 204 SUPERFAMILY SSF46689 11 80 2.69E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS27155 a200ee9d60e9377c6f71e85ccb21dae1 495 Gene3D G3DSA:3.40.50.620 165 323 3.6E-7 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS27155 a200ee9d60e9377c6f71e85ccb21dae1 495 Pfam PF00764 Arginosuccinate synthase 175 281 3.8E-18 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27155 a200ee9d60e9377c6f71e85ccb21dae1 495 Pfam PF00764 Arginosuccinate synthase 377 457 1.9E-16 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27155 a200ee9d60e9377c6f71e85ccb21dae1 495 Gene3D G3DSA:3.90.1260.10 377 467 2.0E-16 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27155 a200ee9d60e9377c6f71e85ccb21dae1 495 SUPERFAMILY SSF69864 335 459 1.44E-27 T 28-03-2018 CNX65_RS27155 a200ee9d60e9377c6f71e85ccb21dae1 495 Gene3D G3DSA:3.90.1260.10 324 376 3.3E-5 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27155 a200ee9d60e9377c6f71e85ccb21dae1 495 SUPERFAMILY SSF52402 174 282 1.83E-14 T 28-03-2018 CNX65_RS27540 a3d417cee19895263c21ee6ea9e267cd 411 Gene3D G3DSA:3.30.360.10 142 411 1.1E-43 T 28-03-2018 CNX65_RS27540 a3d417cee19895263c21ee6ea9e267cd 411 SUPERFAMILY SSF51735 3 153 3.43E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27540 a3d417cee19895263c21ee6ea9e267cd 411 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 3 121 5.6E-18 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS27540 a3d417cee19895263c21ee6ea9e267cd 411 Gene3D G3DSA:3.40.50.720 1 141 4.4E-29 T 28-03-2018 CNX65_RS27540 a3d417cee19895263c21ee6ea9e267cd 411 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 136 213 2.7E-18 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS27540 a3d417cee19895263c21ee6ea9e267cd 411 SUPERFAMILY SSF55347 127 212 5.34E-25 T 28-03-2018 CNX65_RS27540 a3d417cee19895263c21ee6ea9e267cd 411 SUPERFAMILY SSF55347 267 321 5.34E-25 T 28-03-2018 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 SUPERFAMILY SSF54665 154 301 1.83E-39 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 38 46 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Gene3D G3DSA:3.10.20.30 2 73 2.1E-18 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Gene3D G3DSA:3.90.1170.50 153 282 2.7E-35 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 SUPERFAMILY SSF56003 285 892 1.06E-176 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 SMART SM01008 170 282 6.7E-46 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 SUPERFAMILY SSF54292 4 77 6.29E-19 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Pfam PF02738 Molybdopterin-binding domain of aldehyde dehydrogenase 301 830 3.6E-154 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Pfam PF01799 [2Fe-2S] binding domain 72 141 4.9E-26 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 SUPERFAMILY SSF47741 84 148 1.31E-24 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Gene3D G3DSA:3.30.365.10 590 746 2.4E-35 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Gene3D G3DSA:3.30.365.10 417 575 1.4E-49 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Gene3D G3DSA:3.30.365.10 747 894 5.4E-42 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Pfam PF01315 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain 170 282 4.5E-30 T 28-03-2018 IPR000674 Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Gene3D G3DSA:1.10.150.120 74 152 8.6E-28 T 28-03-2018 IPR002888 [2Fe-2S]-binding GO:0016491|GO:0046872|GO:0055114 CNX65_RS13375 d93090e55c246365b9f24d27f350645f 897 Gene3D G3DSA:3.30.365.10 311 416 2.3E-36 T 28-03-2018 IPR008274 Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding GO:0016491|GO:0055114 CNX65_RS14535 6fbae3a57a904f29d2ab05c1b995169a 345 Gene3D G3DSA:3.40.50.10140 27 184 2.4E-14 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14535 6fbae3a57a904f29d2ab05c1b995169a 345 Pfam PF13676 TIR domain 30 136 3.9E-13 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14535 6fbae3a57a904f29d2ab05c1b995169a 345 Pfam PF08305 NPCBM/NEW2 domain 242 313 2.0E-5 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CNX65_RS14535 6fbae3a57a904f29d2ab05c1b995169a 345 SUPERFAMILY SSF52200 25 133 1.24E-7 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14535 6fbae3a57a904f29d2ab05c1b995169a 345 SUPERFAMILY SSF49785 217 315 2.81E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS02380 367e4924921fd0fa2410110b716bbef4 224 Pfam PF01476 LysM domain 177 221 1.1E-4 T 28-03-2018 IPR018392 LysM domain CNX65_RS02380 367e4924921fd0fa2410110b716bbef4 224 SUPERFAMILY SSF53955 47 120 1.35E-31 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS02380 367e4924921fd0fa2410110b716bbef4 224 Gene3D G3DSA:1.10.530.10 16 122 6.2E-30 T 28-03-2018 CNX65_RS02380 367e4924921fd0fa2410110b716bbef4 224 SMART SM00257 176 224 7.7E-4 T 28-03-2018 IPR018392 LysM domain CNX65_RS02380 367e4924921fd0fa2410110b716bbef4 224 Gene3D G3DSA:3.10.350.10 171 223 1.1E-8 T 28-03-2018 CNX65_RS02380 367e4924921fd0fa2410110b716bbef4 224 Pfam PF06737 Transglycosylase-like domain 49 118 4.0E-33 T 28-03-2018 IPR010618 Transglycosylase-like CNX65_RS14135 e508529c1578b4e0af8ff48dd61fa637 388 Gene3D G3DSA:3.40.50.2000 187 351 5.1E-39 T 28-03-2018 CNX65_RS14135 e508529c1578b4e0af8ff48dd61fa637 388 SUPERFAMILY SSF53756 26 367 3.18E-72 T 28-03-2018 CNX65_RS14135 e508529c1578b4e0af8ff48dd61fa637 388 Pfam PF00534 Glycosyl transferases group 1 188 343 6.5E-32 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS14135 e508529c1578b4e0af8ff48dd61fa637 388 Pfam PF13439 Glycosyltransferase Family 4 26 174 1.3E-26 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS14135 e508529c1578b4e0af8ff48dd61fa637 388 Gene3D G3DSA:3.40.50.2000 24 186 3.4E-20 T 28-03-2018 CNX65_RS13465 c1238ed5cdf9e8ebc390b5bb78017e22 328 Gene3D G3DSA:3.50.50.60 1 328 9.0E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13465 c1238ed5cdf9e8ebc390b5bb78017e22 328 SUPERFAMILY SSF51905 1 239 2.85E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13465 c1238ed5cdf9e8ebc390b5bb78017e22 328 Pfam PF01266 FAD dependent oxidoreductase 3 323 1.3E-25 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS01615 05ce84d0d2705e9c9b1cb275a65a7e4a 209 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 134 144 - T 28-03-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CNX65_RS01615 05ce84d0d2705e9c9b1cb275a65a7e4a 209 Gene3D G3DSA:1.10.286.10 26 74 1.5E-21 T 28-03-2018 CNX65_RS01615 05ce84d0d2705e9c9b1cb275a65a7e4a 209 SUPERFAMILY SSF55620 20 207 1.33E-74 T 28-03-2018 CNX65_RS01615 05ce84d0d2705e9c9b1cb275a65a7e4a 209 Gene3D G3DSA:3.30.1130.10 75 209 1.4E-57 T 28-03-2018 CNX65_RS01615 05ce84d0d2705e9c9b1cb275a65a7e4a 209 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 24 207 41.247 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CNX65_RS01615 05ce84d0d2705e9c9b1cb275a65a7e4a 209 Pfam PF01227 GTP cyclohydrolase I 29 206 1.6E-73 T 28-03-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CNX65_RS01615 05ce84d0d2705e9c9b1cb275a65a7e4a 209 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 30 207 9.8E-69 T 28-03-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 SUPERFAMILY SSF51905 3 214 3.33E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.8E-5 T 28-03-2018 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.8E-5 T 28-03-2018 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 180 205 1.8E-5 T 28-03-2018 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 180 198 2.3E-8 T 28-03-2018 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 2.3E-8 T 28-03-2018 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 2.3E-8 T 28-03-2018 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 Gene3D G3DSA:3.50.50.60 2 155 5.7E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 SUPERFAMILY SSF51905 134 362 6.69E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 6 326 2.2E-48 T 28-03-2018 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 Gene3D G3DSA:3.50.50.60 156 216 9.2E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21795 e9474c4f972b23764d5626571dc91b2f 516 Gene3D G3DSA:3.50.50.60 217 363 2.8E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS35070 fedfc9872dbedf4b907c7a715b890c71 89 SMART SM01234 10 77 3.4E-44 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CNX65_RS35070 fedfc9872dbedf4b907c7a715b890c71 89 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 15 81 1.5E-28 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CNX65_RS35070 fedfc9872dbedf4b907c7a715b890c71 89 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 25 77 4.0E-18 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CNX65_RS35070 fedfc9872dbedf4b907c7a715b890c71 89 Pfam PF01809 Haemolytic domain 12 77 3.6E-29 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CNX65_RS35070 fedfc9872dbedf4b907c7a715b890c71 89 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 10 78 24.888 T 28-03-2018 IPR002696 Putative membrane protein insertion efficiency factor CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 SMART SM00387 319 422 2.8E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 Pfam PF00512 His Kinase A (phospho-acceptor) domain 218 266 1.3E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 Pfam PF00672 HAMP domain 171 211 9.4E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 Gene3D G3DSA:3.30.565.10 279 426 4.3E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 SUPERFAMILY SSF47384 203 273 1.35E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 SMART SM00388 217 275 0.0023 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 SUPERFAMILY SSF55874 280 418 6.29E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 SMART SM00304 164 216 1.1E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 356 370 1.4E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 PRINTS PR00344 Bacterial sensor protein C-terminal signature 382 400 1.4E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 Gene3D G3DSA:1.10.287.130 207 278 8.8E-6 T 28-03-2018 CNX65_RS24700 903c443a259ee9065268e9146e6f6b2d 426 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 325 418 2.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS17670 521c6021b0d17d1b84fe2ecf13ffbb75 341 PRINTS PR00069 Aldo-keto reductase signature 135 152 5.9E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS17670 521c6021b0d17d1b84fe2ecf13ffbb75 341 PRINTS PR00069 Aldo-keto reductase signature 104 122 5.9E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS17670 521c6021b0d17d1b84fe2ecf13ffbb75 341 PRINTS PR00069 Aldo-keto reductase signature 40 64 5.9E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS17670 521c6021b0d17d1b84fe2ecf13ffbb75 341 SUPERFAMILY SSF51430 1 308 2.88E-100 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS17670 521c6021b0d17d1b84fe2ecf13ffbb75 341 Gene3D G3DSA:3.20.20.100 1 312 3.6E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS17670 521c6021b0d17d1b84fe2ecf13ffbb75 341 Pfam PF00248 Aldo/keto reductase family 17 306 1.5E-72 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 Gene3D G3DSA:3.30.1330.20 212 320 6.5E-46 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 SMART SM00864 10 202 2.4E-109 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 SUPERFAMILY SSF52490 9 205 1.96E-66 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 Gene3D G3DSA:3.40.50.1440 6 211 2.3E-39 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 ProSitePatterns PS01134 FtsZ protein signature 1. 41 75 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 SMART SM00865 204 321 9.3E-57 T 28-03-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-1445148|Reactome: R-HSA-190840|Reactome: R-HSA-190861|Reactome: R-HSA-2132295|Reactome: R-HSA-2467813|Reactome: R-HSA-2500257|Reactome: R-HSA-3371497|Reactome: R-HSA-380320|Reactome: R-HSA-437239|Reactome: R-HSA-5617833|Reactome: R-HSA-5626467|Reactome: R-HSA-5663220|Reactome: R-HSA-6807878|Reactome: R-HSA-6811434|Reactome: R-HSA-6811436|Reactome: R-HSA-68877|Reactome: R-HSA-8852276|Reactome: R-HSA-8955332|Reactome: R-HSA-983189 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 11 169 1.4E-38 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 8 316 5.4E-128 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 ProSitePatterns PS01135 FtsZ protein signature 2. 94 115 - T 28-03-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 Pfam PF12327 FtsZ family, C-terminal domain 219 313 1.5E-35 T 28-03-2018 IPR024757 Cell division protein FtsZ, C-terminal CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 SUPERFAMILY SSF55307 201 315 3.66E-43 T 28-03-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 6 347 38.347 T 28-03-2018 IPR000158 Cell division protein FtsZ GO:0005525 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 PRINTS PR00423 Cell division protein FtsZ signature 123 144 2.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 PRINTS PR00423 Cell division protein FtsZ signature 95 115 2.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 PRINTS PR00423 Cell division protein FtsZ signature 186 208 2.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS28230 19e6ac0d2dd1aa449edb48836d62da4e 404 PRINTS PR00423 Cell division protein FtsZ signature 209 230 2.3E-51 T 28-03-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 Gene3D G3DSA:1.10.287.1060 245 342 3.9E-4 T 28-03-2018 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 404 433 1.4E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 452 481 1.4E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 375 402 1.4E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 298 327 1.4E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 SMART SM00304 276 336 14.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 SMART SM00304 217 269 1.8E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 Gene3D G3DSA:1.20.120.30 29 191 1.0E-9 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 341 498 1.3E-32 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 SMART SM00283 284 531 8.9E-52 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 Pfam PF12729 Four helix bundle sensory module for signal transduction 13 184 1.1E-11 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 Pfam PF00672 HAMP domain 217 259 1.3E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 SUPERFAMILY SSF58104 237 530 1.01E-56 T 28-03-2018 CNX65_RS00910 b6ea0f43579504ae4e791a92329be95a 532 Gene3D G3DSA:1.10.287.950 343 532 8.1E-40 T 28-03-2018 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 Gene3D G3DSA:1.10.287.130 280 360 1.5E-12 T 28-03-2018 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 SMART SM00388 297 364 9.1E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 SMART SM00304 237 289 1.4E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 SUPERFAMILY SSF158472 237 286 2.35E-8 T 28-03-2018 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 413 519 1.8E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 SUPERFAMILY SSF55874 354 523 5.24E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 Pfam PF00672 HAMP domain 237 286 3.0E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 Gene3D G3DSA:3.30.565.10 370 523 2.0E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 SUPERFAMILY SSF47384 281 364 8.04E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 499 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 460 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 518 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 PRINTS PR00344 Bacterial sensor protein C-terminal signature 464 474 2.6E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 Pfam PF00512 His Kinase A (phospho-acceptor) domain 298 364 1.0E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS31080 2663ba0653b89bf9e2883f209218e661 788 SMART SM00387 410 521 5.4E-28 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 Pfam PF00082 Subtilase family 148 379 2.2E-36 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 SUPERFAMILY SSF49785 421 519 4.21E-17 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 PRINTS PR00723 Subtilisin serine protease family (S8) signature 340 356 2.0E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 PRINTS PR00723 Subtilisin serine protease family (S8) signature 186 199 2.0E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 167 2.0E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 Pfam PF01483 Proprotein convertase P-domain 441 519 4.1E-16 T 28-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 SUPERFAMILY SSF52743 125 390 2.62E-72 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 Gene3D G3DSA:2.60.120.260 410 519 2.2E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 SUPERFAMILY SSF54897 51 116 7.94E-13 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 190 200 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 153 164 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 Gene3D G3DSA:3.40.50.200 104 409 4.5E-77 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 341 351 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 Gene3D G3DSA:3.30.70.80 50 103 4.8E-19 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS32285 3b28c9197fc22d99188ff3534ca72e4b 519 Pfam PF05922 Peptidase inhibitor I9 70 116 4.9E-9 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 207 403 40.846 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 SUPERFAMILY SSF142695 209 380 1.44E-70 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 2 206 38.043 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 Pfam PF00925 GTP cyclohydrolase II 211 377 2.9E-72 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 3 399 55.461 T 28-03-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 Gene3D G3DSA:3.90.870.10 1 215 8.9E-94 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 SUPERFAMILY SSF55821 4 208 2.13E-80 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 4 202 9.3E-75 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 PIRSF PIRSF001259 2 410 6.9E-180 T 28-03-2018 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 210 400 1.1E-74 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS25965 d3791678e61a1d30ea68055f46f3481a 417 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 8 201 5.8E-85 T 28-03-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS15780 2b714fad8719725e2f4528fabc8bab7f 204 Gene3D G3DSA:1.10.10.60 48 203 4.2E-10 T 28-03-2018 CNX65_RS15780 2b714fad8719725e2f4528fabc8bab7f 204 SUPERFAMILY SSF46689 2 71 6.16E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS15780 2b714fad8719725e2f4528fabc8bab7f 204 Gene3D G3DSA:1.10.260.40 2 16 0.53 T 28-03-2018 CNX65_RS15780 2b714fad8719725e2f4528fabc8bab7f 204 Gene3D G3DSA:1.10.10.60 17 47 4.4E-17 T 28-03-2018 CNX65_RS15780 2b714fad8719725e2f4528fabc8bab7f 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 7.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS15780 2b714fad8719725e2f4528fabc8bab7f 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS15780 2b714fad8719725e2f4528fabc8bab7f 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14235 6bbfb8bab945da4d0606fb7bb6bc88b3 332 SUPERFAMILY SSF51735 2 323 6.12E-90 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14235 6bbfb8bab945da4d0606fb7bb6bc88b3 332 Gene3D G3DSA:3.90.25.10 165 330 2.2E-31 T 28-03-2018 CNX65_RS14235 6bbfb8bab945da4d0606fb7bb6bc88b3 332 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 324 3.5E-105 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CNX65_RS14235 6bbfb8bab945da4d0606fb7bb6bc88b3 332 Gene3D G3DSA:3.40.50.720 1 164 1.5E-35 T 28-03-2018 CNX65_RS14235 6bbfb8bab945da4d0606fb7bb6bc88b3 332 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 252 4.9E-54 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS34535 9f240e143e8c59dd76aa870317801d9c 712 Gene3D G3DSA:2.160.20.80 49 491 2.8E-6 T 28-03-2018 CNX65_RS11390 d933bd11b68010bd68d554a265b8ff08 499 PIRSF PIRSF018077 8 496 2.5E-202 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CNX65_RS11390 d933bd11b68010bd68d554a265b8ff08 499 Pfam PF03136 Pup-ligase protein 3 454 3.3E-182 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CNX65_RS11390 d933bd11b68010bd68d554a265b8ff08 499 TIGRFAM TIGR03688 pupylate_PafA2: proteasome accessory factor PafA2 2 485 7.2E-229 T 28-03-2018 IPR022366 Pup deamidase GO:0008233|GO:0016811 CNX65_RS27085 bb331ad702a1b27881cdfbdd3dd70420 592 PIRSF PIRSF003128 1 579 1.7E-156 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CNX65_RS27085 bb331ad702a1b27881cdfbdd3dd70420 592 SUPERFAMILY SSF52540 2 221 2.77E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27085 bb331ad702a1b27881cdfbdd3dd70420 592 Pfam PF02463 RecF/RecN/SMC N terminal domain 7 534 2.2E-16 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CNX65_RS27085 bb331ad702a1b27881cdfbdd3dd70420 592 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 574 8.1E-174 T 28-03-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 CNX65_RS27085 bb331ad702a1b27881cdfbdd3dd70420 592 SUPERFAMILY SSF52540 5 50 2.0E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27085 bb331ad702a1b27881cdfbdd3dd70420 592 SUPERFAMILY SSF52540 360 529 2.0E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27085 bb331ad702a1b27881cdfbdd3dd70420 592 Gene3D G3DSA:3.40.50.300 1 551 1.6E-38 T 28-03-2018 CNX65_RS02705 879343513ef12dafd647ea7403623a36 304 SUPERFAMILY SSF52540 5 222 2.77E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02705 879343513ef12dafd647ea7403623a36 304 Pfam PF00005 ABC transporter 21 161 1.8E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS02705 879343513ef12dafd647ea7403623a36 304 Gene3D G3DSA:3.40.50.300 2 264 9.5E-63 T 28-03-2018 CNX65_RS02705 879343513ef12dafd647ea7403623a36 304 SMART SM00382 30 209 9.1E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02705 879343513ef12dafd647ea7403623a36 304 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS02705 879343513ef12dafd647ea7403623a36 304 Pfam PF13732 Domain of unknown function (DUF4162) 215 297 9.6E-9 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CNX65_RS30075 70e4f5dc927800317438ddc845ffa5a4 208 TIGRFAM TIGR02365 dha_L_ycgS: dihydroxyacetone kinase, L subunit 12 203 7.0E-65 T 28-03-2018 IPR012737 Dihydroxyacetone kinase, subunit L GO:0016772 CNX65_RS30075 70e4f5dc927800317438ddc845ffa5a4 208 SMART SM01120 32 204 7.6E-67 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS30075 70e4f5dc927800317438ddc845ffa5a4 208 SUPERFAMILY SSF101473 7 204 3.53E-51 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS30075 70e4f5dc927800317438ddc845ffa5a4 208 Pfam PF02734 DAK2 domain 32 203 2.5E-50 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS22615 4b224628a3abb119778fc6667aa6d576 59 Gene3D G3DSA:1.10.10.60 3 45 6.7E-6 T 28-03-2018 CNX65_RS22615 4b224628a3abb119778fc6667aa6d576 59 Pfam PF12728 Helix-turn-helix domain 10 47 4.8E-8 T 28-03-2018 CNX65_RS31180 bfe3c572e50fe8ac16e1e566fe769f66 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 321 348 5.0E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS31180 bfe3c572e50fe8ac16e1e566fe769f66 359 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 255 286 8.0E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS31180 bfe3c572e50fe8ac16e1e566fe769f66 359 SUPERFAMILY SSF53448 9 241 3.92E-69 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31180 bfe3c572e50fe8ac16e1e566fe769f66 359 SUPERFAMILY SSF53448 272 310 3.92E-69 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31180 bfe3c572e50fe8ac16e1e566fe769f66 359 Pfam PF00483 Nucleotidyl transferase 9 235 4.0E-45 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CNX65_RS31180 bfe3c572e50fe8ac16e1e566fe769f66 359 Gene3D G3DSA:2.160.10.10 258 359 4.3E-20 T 28-03-2018 CNX65_RS31180 bfe3c572e50fe8ac16e1e566fe769f66 359 Gene3D G3DSA:3.90.550.10 8 257 1.3E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS06230 f7e615327197c3944793076e2f062f49 187 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 36 148 4.4E-30 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CNX65_RS06230 f7e615327197c3944793076e2f062f49 187 SUPERFAMILY SSF55486 6 147 2.69E-37 T 28-03-2018 CNX65_RS06230 f7e615327197c3944793076e2f062f49 187 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 2 176 20.306 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CNX65_RS06230 f7e615327197c3944793076e2f062f49 187 Gene3D G3DSA:3.40.390.30 2 166 1.1E-41 T 28-03-2018 IPR023091 Metalloprotease catalytic domain, predicted GO:0004222 CNX65_RS06230 f7e615327197c3944793076e2f062f49 187 Pfam PF02130 Uncharacterized protein family UPF0054 17 146 1.1E-34 T 28-03-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 CNX65_RS06230 f7e615327197c3944793076e2f062f49 187 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 118 128 - T 28-03-2018 IPR020549 Endoribonuclease YbeY, conserved site CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 Gene3D G3DSA:3.40.50.2300 53 170 1.5E-26 T 28-03-2018 CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 SUPERFAMILY SSF47413 1 56 2.56E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 SMART SM00354 1 68 3.1E-30 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 SUPERFAMILY SSF53822 58 326 7.97E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 Pfam PF13377 Periplasmic binding protein-like domain 165 323 8.7E-37 T 28-03-2018 CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 Gene3D G3DSA:1.10.260.40 1 52 6.8E-25 T 28-03-2018 CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 28-03-2018 CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 Gene3D G3DSA:3.40.50.2300 171 301 4.6E-44 T 28-03-2018 CNX65_RS09290 ac6cfabadd3f7c8a5cc04b8526ae02a9 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 2.8E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS13040 b9142572987f58063157c4da4801861c 192 Pfam PF13302 Acetyltransferase (GNAT) domain 15 157 6.1E-31 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS13040 b9142572987f58063157c4da4801861c 192 Gene3D G3DSA:3.40.630.30 2 192 2.6E-30 T 28-03-2018 CNX65_RS13040 b9142572987f58063157c4da4801861c 192 SUPERFAMILY SSF55729 8 183 5.0E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 SUPERFAMILY SSF81296 495 588 5.32E-12 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 Gene3D G3DSA:3.20.20.80 181 496 4.7E-41 T 28-03-2018 CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 Pfam PF03442 Carbohydrate binding domain X2 494 577 1.1E-15 T 28-03-2018 IPR005102 Carbohydrate binding X2 domain CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 SMART SM00637 32 131 1.7E-44 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 Pfam PF00553 Cellulose binding domain 32 131 4.4E-31 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 Gene3D G3DSA:2.60.40.10 497 588 3.3E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 Gene3D G3DSA:2.60.40.10 589 688 7.7E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 SUPERFAMILY SSF51445 151 487 5.62E-61 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 Gene3D G3DSA:2.60.40.290 23 131 2.2E-36 T 28-03-2018 CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 SUPERFAMILY SSF49384 28 133 6.63E-32 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS14075 9a2be995c509dc2296c75665eab8f145 689 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 186 465 6.0E-52 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 PRINTS PR00395 Ribosomal protein S2 signature 37 46 1.5E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 PRINTS PR00395 Ribosomal protein S2 signature 6 24 1.5E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 PRINTS PR00395 Ribosomal protein S2 signature 175 186 1.5E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 PRINTS PR00395 Ribosomal protein S2 signature 196 210 1.5E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 PRINTS PR00395 Ribosomal protein S2 signature 158 175 1.5E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 PRINTS PR00395 Ribosomal protein S2 signature 87 104 1.5E-38 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 Pfam PF00318 Ribosomal protein S2 9 224 1.1E-95 T 28-03-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 Gene3D G3DSA:3.40.50.10490 5 269 8.5E-97 T 28-03-2018 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 224 7.7E-108 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 SUPERFAMILY SSF52313 6 225 3.66E-93 T 28-03-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 28-03-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 CNX65_RS29005 119fc47bcd77bd3122163c4556671a4b 294 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 225 42.147 T 28-03-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS10555 8671bb466dd84af9653c709d57dccf2f 816 SMART SM00387 526 636 7.6E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10555 8671bb466dd84af9653c709d57dccf2f 816 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 529 632 2.6E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10555 8671bb466dd84af9653c709d57dccf2f 816 Gene3D G3DSA:3.30.565.10 444 635 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10555 8671bb466dd84af9653c709d57dccf2f 816 Pfam PF08376 Nitrate and nitrite sensing 68 288 1.5E-19 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CNX65_RS10555 8671bb466dd84af9653c709d57dccf2f 816 Pfam PF00672 HAMP domain 367 406 2.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS10555 8671bb466dd84af9653c709d57dccf2f 816 SUPERFAMILY SSF55874 509 634 1.44E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS21020 986a30ace5cf069fb402642d5a46c635 266 TIGRFAM TIGR02434 CobF: precorrin-6A synthase (deacetylating) 16 264 3.1E-98 T 28-03-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 CNX65_RS21020 986a30ace5cf069fb402642d5a46c635 266 Gene3D G3DSA:3.40.1010.10 15 167 1.2E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS21020 986a30ace5cf069fb402642d5a46c635 266 PIRSF PIRSF036525 14 266 2.0E-99 T 28-03-2018 IPR012797 Cobalamin (vitamin B12) biosynthesis CobF, precorrin-6A synthase GO:0009236|GO:0043819 KEGG: 00860+2.1.1.152|MetaCyc: PWY-7376 CNX65_RS21020 986a30ace5cf069fb402642d5a46c635 266 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 19 239 6.0E-30 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS21020 986a30ace5cf069fb402642d5a46c635 266 Gene3D G3DSA:3.30.950.10 168 264 1.2E-44 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS21020 986a30ace5cf069fb402642d5a46c635 266 SUPERFAMILY SSF53790 16 265 6.67E-37 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS34130 0ee05c1ce3f2702c09a094b2dfb9d057 382 Gene3D G3DSA:3.20.20.30 4 373 2.9E-89 T 28-03-2018 CNX65_RS34130 0ee05c1ce3f2702c09a094b2dfb9d057 382 SUPERFAMILY SSF51679 26 369 3.24E-90 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS34130 0ee05c1ce3f2702c09a094b2dfb9d057 382 Pfam PF00296 Luciferase-like monooxygenase 8 337 6.8E-84 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS34005 a0f30361be08508846cceb4e8fc61cc8 324 Gene3D G3DSA:3.40.50.720 1 56 2.6E-5 T 28-03-2018 CNX65_RS34005 a0f30361be08508846cceb4e8fc61cc8 324 SUPERFAMILY SSF51735 1 219 6.55E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34005 a0f30361be08508846cceb4e8fc61cc8 324 Gene3D G3DSA:3.40.50.720 57 230 8.9E-11 T 28-03-2018 CNX65_RS22865 2cf911d3422458c007f18b584bd1eaca 624 SUPERFAMILY SSF102114 327 540 3.53E-18 T 28-03-2018 CNX65_RS22865 2cf911d3422458c007f18b584bd1eaca 624 Gene3D G3DSA:3.40.50.280 119 246 8.8E-7 T 28-03-2018 CNX65_RS22865 2cf911d3422458c007f18b584bd1eaca 624 Pfam PF04055 Radical SAM superfamily 338 532 4.0E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS22865 2cf911d3422458c007f18b584bd1eaca 624 Gene3D G3DSA:3.20.20.70 313 591 3.6E-18 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS22865 2cf911d3422458c007f18b584bd1eaca 624 SMART SM00729 331 581 2.8E-8 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS31620 ecc9f4f0c795184ba16aa91afd23b184 356 Gene3D G3DSA:3.20.20.140 4 346 3.4E-79 T 28-03-2018 CNX65_RS31620 ecc9f4f0c795184ba16aa91afd23b184 356 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 16 344 7.0E-82 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CNX65_RS31620 ecc9f4f0c795184ba16aa91afd23b184 356 Pfam PF00962 Adenosine/AMP deaminase 15 343 1.8E-84 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CNX65_RS31620 ecc9f4f0c795184ba16aa91afd23b184 356 SUPERFAMILY SSF51556 11 346 3.2E-73 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS20840 9e7be6a91d25101ebbe58c9a1bc984e8 259 SMART SM00346 15 105 7.7E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS20840 9e7be6a91d25101ebbe58c9a1bc984e8 259 Gene3D G3DSA:3.30.450.40 79 252 1.1E-28 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS20840 9e7be6a91d25101ebbe58c9a1bc984e8 259 SUPERFAMILY SSF55781 92 250 2.81E-28 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS20840 9e7be6a91d25101ebbe58c9a1bc984e8 259 SUPERFAMILY SSF46785 15 85 3.21E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20840 9e7be6a91d25101ebbe58c9a1bc984e8 259 Pfam PF01614 Bacterial transcriptional regulator 134 250 8.7E-7 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS20840 9e7be6a91d25101ebbe58c9a1bc984e8 259 Pfam PF09339 IclR helix-turn-helix domain 17 66 9.1E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS20840 9e7be6a91d25101ebbe58c9a1bc984e8 259 Gene3D G3DSA:1.10.10.10 2 76 2.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17915 0715aa247ca2c2ab8f8a08b1fdcdb630 394 SUPERFAMILY SSF49384 34 136 4.12E-28 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS17915 0715aa247ca2c2ab8f8a08b1fdcdb630 394 Gene3D G3DSA:2.60.120.260 178 392 2.6E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS17915 0715aa247ca2c2ab8f8a08b1fdcdb630 394 Pfam PF00553 Cellulose binding domain 38 136 1.5E-28 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS17915 0715aa247ca2c2ab8f8a08b1fdcdb630 394 Gene3D G3DSA:2.60.40.290 29 136 4.8E-30 T 28-03-2018 CNX65_RS17915 0715aa247ca2c2ab8f8a08b1fdcdb630 394 SUPERFAMILY SSF49899 211 344 7.19E-6 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS17915 0715aa247ca2c2ab8f8a08b1fdcdb630 394 SMART SM00637 38 136 7.9E-41 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 87 6.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 Gene3D G3DSA:1.10.10.10 17 90 6.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 62 78 1.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 48 62 1.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 SMART SM00345 29 88 1.9E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 Gene3D G3DSA:1.20.120.530 93 248 4.7E-34 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 SMART SM00895 113 235 1.4E-22 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 SUPERFAMILY SSF46785 19 92 1.36E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 SUPERFAMILY SSF48008 112 238 1.96E-29 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS13415 51834b9ae75476f037a685d211fb5b50 254 Pfam PF07729 FCD domain 113 233 1.0E-26 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 Gene3D G3DSA:3.40.50.620 3 128 2.9E-15 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 Pfam PF00582 Universal stress protein family 5 126 3.7E-10 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 Pfam PF00582 Universal stress protein family 134 268 1.6E-24 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 SUPERFAMILY SSF52402 134 268 2.93E-27 T 28-03-2018 CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 Gene3D G3DSA:3.40.50.620 129 268 2.3E-29 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 SUPERFAMILY SSF52402 4 129 2.01E-14 T 28-03-2018 CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 PRINTS PR01438 Universal stress protein signature 132 150 1.9E-10 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS09660 cfd059a369ce529c609250855de50a86 274 PRINTS PR01438 Universal stress protein signature 246 268 1.9E-10 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS09010 33d1a15e1e02706dd4ad378c83ca11a6 170 Pfam PF00486 Transcriptional regulatory protein, C terminal 73 146 6.1E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS09010 33d1a15e1e02706dd4ad378c83ca11a6 170 Gene3D G3DSA:1.10.10.10 52 152 8.8E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09010 33d1a15e1e02706dd4ad378c83ca11a6 170 SUPERFAMILY SSF46894 60 147 3.97E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS09010 33d1a15e1e02706dd4ad378c83ca11a6 170 SMART SM00862 73 146 2.5E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 86 97 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 158 169 - T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 SUPERFAMILY SSF51569 4 340 1.47E-101 T 28-03-2018 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 TIGRFAM TIGR01520 FruBisAldo_II_A: fructose-bisphosphate aldolase, class II 3 338 1.2E-143 T 28-03-2018 IPR006411 Fructose-bisphosphate aldolase, class II, yeast/E. coli subtype GO:0004332|GO:0006096 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 Pfam PF01116 Fructose-bisphosphate aldolase class-II 9 340 3.3E-83 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 PIRSF PIRSF001359 6 341 4.8E-67 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 Gene3D G3DSA:3.20.20.70 1 343 2.7E-105 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS34175 1c1423e430c9c7bb0e7c8805f0f2b2a7 344 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 10 340 1.9E-77 T 28-03-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 CNX65_RS08165 8f767c91558318ed7b1e490dc05dfeb5 257 Pfam PF08386 TAP-like protein 161 250 7.5E-17 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS08165 8f767c91558318ed7b1e490dc05dfeb5 257 Gene3D G3DSA:3.40.50.1820 106 257 3.3E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS08165 8f767c91558318ed7b1e490dc05dfeb5 257 Gene3D G3DSA:3.40.50.1820 36 105 1.2E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS08165 8f767c91558318ed7b1e490dc05dfeb5 257 SUPERFAMILY SSF53474 113 225 4.7E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 Gene3D G3DSA:3.50.50.60 234 321 6.3E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 6 305 8.7E-119 T 28-03-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 134 154 - T 28-03-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 Gene3D G3DSA:3.50.50.60 127 233 3.2E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 SUPERFAMILY SSF51905 6 305 1.6E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 39 54 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 127 139 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 105 113 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 194 210 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 142 166 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 60 70 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 233 254 1.5E-77 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 4.3E-33 T 28-03-2018 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 4.3E-33 T 28-03-2018 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 4.3E-33 T 28-03-2018 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 4.3E-33 T 28-03-2018 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 4.3E-33 T 28-03-2018 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 Gene3D G3DSA:3.50.50.60 2 126 3.1E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS35000 c9ca8e08f45c092d0a29cc06dd2f0425 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 294 5.0E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 Gene3D G3DSA:1.10.287.950 164 331 1.1E-10 T 28-03-2018 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 Gene3D G3DSA:1.10.287.950 332 538 1.1E-42 T 28-03-2018 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 SUPERFAMILY SSF58104 243 536 1.31E-57 T 28-03-2018 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 342 503 4.8E-31 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 SMART SM00304 222 275 0.0013 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 SMART SM00304 282 338 110.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 SMART SM00283 283 537 3.2E-46 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 381 408 1.7E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 8 33 1.7E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 458 487 1.7E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 410 439 1.7E-20 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS20980 0dd5f143aa05bec5d8dad6b1e98d4085 538 Pfam PF02203 Tar ligand binding domain homologue 5 51 2.1E-7 T 28-03-2018 IPR003122 Chemotaxis methyl-accepting receptor Tar-related, ligand-binding GO:0006935|GO:0007165 CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 Pfam PF00082 Subtilase family 147 376 2.4E-34 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 339 349 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 Gene3D G3DSA:3.40.50.200 103 390 2.6E-74 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 Gene3D G3DSA:3.30.70.80 44 102 8.6E-19 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 338 354 2.1E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 185 198 2.1E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 PRINTS PR00723 Subtilisin serine protease family (S8) signature 147 166 2.1E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 Pfam PF05922 Peptidase inhibitor I9 47 114 2.1E-9 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 152 163 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 SUPERFAMILY SSF52743 98 394 1.57E-71 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08570 82e37aa03bb9f9bdcfeeff3d3db3a283 397 SUPERFAMILY SSF54897 45 115 5.21E-15 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.40.50.980 1699 1847 4.9E-35 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF47336 2044 2117 7.2E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF52777 1295 1538 4.11E-30 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF00550 Phosphopantetheine attachment site 1016 1077 5.8E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF00550 Phosphopantetheine attachment site 2055 2116 1.6E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.40.50.1820 2129 2389 4.5E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SMART SM00823 Phosphopantetheine attachment site 1014 1082 0.0038 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SMART SM00823 Phosphopantetheine attachment site 2052 2120 0.0042 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.30.559.10 1088 1304 1.9E-29 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF52777 47 219 2.0E-45 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 519 929 1.0E-129 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1579 1969 2.7E-119 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:1.10.1200.10 1020 1087 1.5E-20 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF47336 1008 1076 2.88E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF00668 Condensation domain 43 476 3.6E-84 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF00668 Condensation domain 1108 1528 4.0E-45 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF52777 223 464 4.56E-57 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1038 1053 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.30.300.30 900 1019 8.8E-40 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.30.300.30 1940 2055 3.8E-37 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 ProSitePatterns PS00455 Putative AMP-binding domain signature. 641 652 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF56801 455 1024 1.96E-150 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:1.10.1200.10 2056 2128 2.0E-20 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF56801 1553 2065 1.57E-138 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.40.50.980 1549 1698 5.2E-36 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.40.50.980 490 647 3.3E-42 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF00501 AMP-binding enzyme 1556 1945 9.9E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF00501 AMP-binding enzyme 500 905 5.1E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.40.50.980 648 812 1.7E-37 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF00975 Thioesterase domain 2140 2378 3.9E-17 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF53474 2129 2387 3.98E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 SUPERFAMILY SSF52777 1104 1308 4.78E-33 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:2.30.38.10 1855 1934 2.3E-21 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:2.30.38.10 816 895 5.8E-23 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Gene3D G3DSA:3.30.559.10 33 237 1.9E-36 T 28-03-2018 CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1697 1708 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF13193 AMP-binding enzyme C-terminal domain 913 986 1.4E-14 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 Pfam PF13193 AMP-binding enzyme C-terminal domain 1953 2024 1.0E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18105 4ed2734d4c263a9de2c5c0d3a78e67e4 2395 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2076 2091 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18495 525f544338ec57603ef19d65ae803f58 65 Gene3D G3DSA:3.30.70.20 3 65 1.8E-5 T 28-03-2018 CNX65_RS18495 525f544338ec57603ef19d65ae803f58 65 SUPERFAMILY SSF54862 5 61 2.27E-9 T 28-03-2018 CNX65_RS18495 525f544338ec57603ef19d65ae803f58 65 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 4.9E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS18495 525f544338ec57603ef19d65ae803f58 65 PRINTS PR00352 3Fe-4S ferredoxin signature 50 62 4.9E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS18495 525f544338ec57603ef19d65ae803f58 65 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 4.9E-6 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS18495 525f544338ec57603ef19d65ae803f58 65 Pfam PF13459 4Fe-4S single cluster domain 6 61 4.1E-13 T 28-03-2018 CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 424 670 1.4E-45 T 28-03-2018 CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 TIGRFAM TIGR02632 RhaD_aldol-ADH: rhamnulose-1-phosphate aldolase/alcohol dehydrogenase 5 676 0.0 T 28-03-2018 IPR013454 Bifunctional rhamnulose-1-phosphate aldolase/alcohol dehydrogenase CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 Gene3D G3DSA:3.40.225.10 2 240 5.3E-39 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 SUPERFAMILY SSF53639 5 210 3.92E-30 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 587 604 2.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 419 436 2.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 634 654 2.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 540 556 2.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 492 503 2.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 566 585 2.8E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 SMART SM01007 6 208 1.8E-34 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 6 206 5.7E-23 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 Gene3D G3DSA:3.40.225.10 247 396 0.038 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 SUPERFAMILY SSF51735 409 673 3.4E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15460 e407f15cae56f5e76c0a78b0991e4ff4 676 Gene3D G3DSA:3.40.50.720 397 673 6.3E-54 T 28-03-2018 CNX65_RS28800 331e29bc0a5ffc37dd3e93fe40cb3957 344 Gene3D G3DSA:3.30.2010.10 62 153 7.2E-18 T 28-03-2018 CNX65_RS28800 331e29bc0a5ffc37dd3e93fe40cb3957 344 Pfam PF01435 Peptidase family M48 71 265 1.8E-24 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CNX65_RS03850 6f94d36102b83460212c26b3ae6fa583 143 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 131 2.7E-9 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CNX65_RS03850 6f94d36102b83460212c26b3ae6fa583 143 SUPERFAMILY SSF55961 3 136 1.06E-17 T 28-03-2018 CNX65_RS03850 6f94d36102b83460212c26b3ae6fa583 143 Gene3D G3DSA:3.30.530.20 1 142 2.2E-17 T 28-03-2018 IPR023393 START-like domain CNX65_RS34270 86e42349e39275154d548b2bd877252d 184 Gene3D G3DSA:3.40.50.2020 3 184 2.2E-32 T 28-03-2018 CNX65_RS34270 86e42349e39275154d548b2bd877252d 184 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 184 23.678 T 28-03-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS34270 86e42349e39275154d548b2bd877252d 184 SUPERFAMILY SSF53271 10 181 1.01E-31 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS34270 86e42349e39275154d548b2bd877252d 184 Pfam PF00156 Phosphoribosyl transferase domain 98 164 6.2E-10 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CNX65_RS34270 86e42349e39275154d548b2bd877252d 184 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 17 181 6.4E-35 T 28-03-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 Gene3D G3DSA:3.40.50.300 42 194 2.7E-16 T 28-03-2018 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 Pfam PF00931 NB-ARC domain 66 254 4.0E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 Gene3D G3DSA:1.25.40.10 448 593 1.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 SUPERFAMILY SSF52540 45 309 3.55E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 Gene3D G3DSA:1.25.40.10 611 698 1.3E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 Gene3D G3DSA:3.30.70.100 594 610 0.0076 T 28-03-2018 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 PRINTS PR00364 Disease resistance protein signature 155 169 7.3E-9 T 28-03-2018 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 PRINTS PR00364 Disease resistance protein signature 242 256 7.3E-9 T 28-03-2018 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 PRINTS PR00364 Disease resistance protein signature 76 91 7.3E-9 T 28-03-2018 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 SMART SM00028 533 566 100.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 SMART SM00028 651 684 19.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 SMART SM00028 493 526 340.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 SMART SM00028 613 646 25.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS14560 48281e90127ca33cf82a380a9b96f654 703 SUPERFAMILY SSF48452 492 697 1.82E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16070 a8cc3e67547a6bdbd5fc7ee101e18cec 241 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 44 216 1.2E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS16070 a8cc3e67547a6bdbd5fc7ee101e18cec 241 SUPERFAMILY SSF52266 91 226 5.92E-36 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS16070 a8cc3e67547a6bdbd5fc7ee101e18cec 241 SUPERFAMILY SSF52266 33 60 5.92E-36 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS16070 a8cc3e67547a6bdbd5fc7ee101e18cec 241 Gene3D G3DSA:3.40.50.1110 26 211 8.2E-30 T 28-03-2018 CNX65_RS16070 a8cc3e67547a6bdbd5fc7ee101e18cec 241 Gene3D G3DSA:3.40.50.1110 212 232 0.21 T 28-03-2018 CNX65_RS11900 231484cf47265071a277f71aff6c286f 257 Pfam PF01618 MotA/TolQ/ExbB proton channel family 100 219 7.7E-24 T 28-03-2018 IPR002898 MotA/TolQ/ExbB proton channel GO:0006810|GO:0008565|GO:0016020 CNX65_RS11900 231484cf47265071a277f71aff6c286f 257 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 185 202 - T 28-03-2018 IPR000540 Flagellar motor protein MotA, conserved site CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 304 321 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 46 382 5.0E-101 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 Gene3D G3DSA:3.40.50.1700 395 571 7.5E-13 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 SUPERFAMILY SSF51445 29 416 1.37E-103 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 Gene3D G3DSA:3.20.20.300 28 394 7.1E-103 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 457 570 8.2E-11 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 PRINTS PR00133 Glycosyl hydrolase family 3 signature 304 322 6.6E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 PRINTS PR00133 Glycosyl hydrolase family 3 signature 227 243 6.6E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 PRINTS PR00133 Glycosyl hydrolase family 3 signature 144 163 6.6E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS01290 e3de23bb9e10bfb5dae07b0a759dda28 580 SUPERFAMILY SSF52279 447 580 4.58E-13 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS18440 7901acb83bc523a9c59abf07b7f13fd0 158 Gene3D G3DSA:3.10.450.50 1 147 9.0E-23 T 28-03-2018 CNX65_RS18440 7901acb83bc523a9c59abf07b7f13fd0 158 SUPERFAMILY SSF54427 7 152 6.48E-19 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS18440 7901acb83bc523a9c59abf07b7f13fd0 158 Pfam PF13577 SnoaL-like domain 6 132 1.6E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS15770 d60903b4123575f1677cb984954c9342 566 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 284 352 5.1E-7 T 28-03-2018 CNX65_RS15770 d60903b4123575f1677cb984954c9342 566 Gene3D G3DSA:2.60.40.680 207 289 0.0097 T 28-03-2018 CNX65_RS15770 d60903b4123575f1677cb984954c9342 566 Gene3D G3DSA:2.130.10.130 290 425 5.0E-15 T 28-03-2018 CNX65_RS15770 d60903b4123575f1677cb984954c9342 566 SUPERFAMILY SSF69318 212 466 1.57E-23 T 28-03-2018 CNX65_RS15770 d60903b4123575f1677cb984954c9342 566 Gene3D G3DSA:3.90.1720.10 70 206 1.3E-8 T 28-03-2018 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 149 194 3.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 Pfam PF00072 Response regulator receiver domain 3 98 2.3E-16 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 Gene3D G3DSA:1.10.10.10 133 214 7.0E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 SUPERFAMILY SSF52172 2 162 5.89E-23 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 SUPERFAMILY SSF46894 145 196 1.81E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 SMART SM00448 1 121 2.7E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 Gene3D G3DSA:3.40.50.2300 1 132 1.6E-29 T 28-03-2018 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 SMART SM00421 147 209 3.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 180 192 8.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 150 164 8.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02690 a93a97257050d87ccf20437b2c09d753 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 164 180 8.6E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS17525 1b1dfff54f0bbbf39a1d4c8a7efc2822 300 SUPERFAMILY SSF52317 4 157 1.19E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS17525 1b1dfff54f0bbbf39a1d4c8a7efc2822 300 Gene3D G3DSA:3.50.30.60 153 285 3.0E-32 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CNX65_RS17525 1b1dfff54f0bbbf39a1d4c8a7efc2822 300 PIRSF PIRSF028757 3 288 1.6E-53 T 28-03-2018 IPR003507 Peptidase family S66 CNX65_RS17525 1b1dfff54f0bbbf39a1d4c8a7efc2822 300 Gene3D G3DSA:3.40.50.10740 3 152 4.7E-42 T 28-03-2018 IPR027478 Murein tetrapeptide carboxypeptidase, N-terminal domain CNX65_RS17525 1b1dfff54f0bbbf39a1d4c8a7efc2822 300 Pfam PF02016 LD-carboxypeptidase 11 274 5.4E-61 T 28-03-2018 IPR003507 Peptidase family S66 CNX65_RS17525 1b1dfff54f0bbbf39a1d4c8a7efc2822 300 SUPERFAMILY SSF141986 146 279 2.35E-32 T 28-03-2018 IPR027461 LD-carboxypeptidase A, C-terminal domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SUPERFAMILY SSF55785 120 227 5.59E-17 T 28-03-2018 IPR000014 PAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SUPERFAMILY SSF55781 232 396 5.02E-22 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 575 757 9.9E-47 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Pfam PF08447 PAS fold 139 222 4.3E-14 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SUPERFAMILY SSF55785 392 510 2.93E-22 T 28-03-2018 IPR000014 PAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 115 235 2.2E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 401 518 3.1E-22 T 28-03-2018 IPR000014 PAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Pfam PF00989 PAS fold 406 455 1.1E-10 T 28-03-2018 IPR013767 PAS fold GO:0006355 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Gene3D G3DSA:3.60.40.10 524 758 2.1E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SMART SM00086 187 229 0.045 T 28-03-2018 IPR001610 PAC motif CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SMART SM00086 476 512 4.2 T 28-03-2018 IPR001610 PAC motif CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SUPERFAMILY SSF55874 793 883 1.72E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SUPERFAMILY SSF81606 562 757 8.37E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Gene3D G3DSA:3.30.450.20 114 242 3.1E-21 T 28-03-2018 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Pfam PF01590 GAF domain 254 387 7.9E-13 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SMART SM00065 251 401 2.5E-12 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SUPERFAMILY SSF52091 911 1001 8.04E-10 T 28-03-2018 IPR002645 STAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SMART SM00091 115 184 5.1E-9 T 28-03-2018 IPR000014 PAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SMART SM00091 405 471 5.6E-13 T 28-03-2018 IPR000014 PAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 SMART SM00331 548 758 3.4E-36 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Pfam PF13581 Histidine kinase-like ATPase domain 769 880 2.9E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Gene3D G3DSA:3.30.450.20 394 523 6.9E-28 T 28-03-2018 CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Gene3D G3DSA:3.30.450.40 243 393 3.2E-22 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Pfam PF13466 STAS domain 919 1001 3.3E-14 T 28-03-2018 IPR002645 STAS domain CNX65_RS18705 ed484f87c3c31541df8abdfb4bf1fda8 1016 Gene3D G3DSA:3.30.565.10 759 949 3.8E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 Pfam PF00108 Thiolase, N-terminal domain 13 265 1.6E-54 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 SUPERFAMILY SSF53901 10 271 1.93E-60 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 Gene3D G3DSA:3.40.47.10 277 396 1.2E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 SUPERFAMILY SSF53901 277 397 3.46E-38 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 16 397 2.4E-124 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 Pfam PF02803 Thiolase, C-terminal domain 278 397 7.8E-36 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 ProSitePatterns PS00737 Thiolases signature 2. 344 360 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 PIRSF PIRSF000429 7 400 1.4E-119 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 Gene3D G3DSA:3.40.47.10 5 152 2.6E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS07660 d55c62dc762c3008ddc1d6135d7dd20f 406 Gene3D G3DSA:3.40.47.10 155 276 1.6E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS28245 42a4be3f22f67bb8d793e1cb226732d3 372 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 16 364 5.4E-83 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS28245 42a4be3f22f67bb8d793e1cb226732d3 372 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 17 155 2.2E-36 T 28-03-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS28245 42a4be3f22f67bb8d793e1cb226732d3 372 SUPERFAMILY SSF53756 17 371 4.83E-95 T 28-03-2018 CNX65_RS28245 42a4be3f22f67bb8d793e1cb226732d3 372 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 201 356 3.8E-35 T 28-03-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CNX65_RS28245 42a4be3f22f67bb8d793e1cb226732d3 372 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 17 370 30.371 T 28-03-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0009252|GO:0050511 KEGG: 00052+2.4.1.22|KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS28245 42a4be3f22f67bb8d793e1cb226732d3 372 Gene3D G3DSA:3.40.50.2000 189 353 2.9E-32 T 28-03-2018 CNX65_RS28245 42a4be3f22f67bb8d793e1cb226732d3 372 Gene3D G3DSA:3.40.50.2000 9 188 8.3E-30 T 28-03-2018 CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 Gene3D G3DSA:3.20.80.10 114 284 5.5E-33 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 SUPERFAMILY SSF46689 3 53 3.94E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 SMART SM00871 126 284 2.4E-23 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 Gene3D G3DSA:1.10.10.60 57 113 2.1E-9 T 28-03-2018 CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 Pfam PF12833 Helix-turn-helix domain 25 103 1.7E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 Pfam PF06445 GyrI-like small molecule binding domain 126 283 1.0E-22 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 Gene3D G3DSA:1.10.10.60 2 56 5.4E-9 T 28-03-2018 CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 SUPERFAMILY SSF46689 55 105 3.18E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 SUPERFAMILY SSF55136 126 285 2.88E-20 T 28-03-2018 CNX65_RS08995 b1dc726ce42e5b61b5362a810034fc4b 286 SMART SM00342 19 102 9.2E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 Gene3D G3DSA:3.30.70.920 227 318 1.9E-14 T 28-03-2018 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 Gene3D G3DSA:3.30.70.920 55 141 2.2E-8 T 28-03-2018 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 SUPERFAMILY SSF46785 4 50 3.27E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 Gene3D G3DSA:1.10.10.10 1 52 9.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 Gene3D G3DSA:1.10.10.10 172 222 6.9E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 SUPERFAMILY SSF46785 174 221 1.22E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 SUPERFAMILY SSF54909 239 313 6.7E-9 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 4.3E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 4.3E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 4.3E-6 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 SMART SM00344 175 280 9.1E-6 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 SMART SM00344 4 107 7.4E-5 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 3.3E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 Pfam PF13404 AsnC-type helix-turn-helix domain 175 216 4.1E-12 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS15760 d7db6334750cbf223b043d5d05d952d4 319 Pfam PF01037 Lrp/AsnC ligand binding domain 242 311 3.8E-10 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 Pfam PF03793 PASTA domain 581 640 2.3E-8 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 Pfam PF03793 PASTA domain 782 838 5.3E-13 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 Pfam PF03793 PASTA domain 717 779 3.5E-15 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 Pfam PF03793 PASTA domain 646 710 1.2E-9 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 SMART SM00740 642 710 4.9E-5 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 SMART SM00740 782 840 3.1E-9 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 SMART SM00740 711 779 1.8E-13 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 SMART SM00740 575 641 2.8E-9 T 28-03-2018 IPR005543 PASTA domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 SUPERFAMILY SSF54184 782 837 8.24E-8 T 28-03-2018 CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 SMART SM00220 17 266 7.6E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 Gene3D G3DSA:3.30.200.20 2 99 6.5E-22 T 28-03-2018 CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 Gene3D G3DSA:1.10.510.10 100 279 3.4E-46 T 28-03-2018 CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 136 148 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 SUPERFAMILY SSF56112 15 366 8.52E-76 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS06910 86a64aecd720b3e468df0c5ac6d0767d 840 Pfam PF00069 Protein kinase domain 18 260 1.1E-43 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS14525 04e9ef97503a1bbef5da39c0d8bcc9c2 193 SUPERFAMILY SSF48150 5 145 1.74E-13 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS14525 04e9ef97503a1bbef5da39c0d8bcc9c2 193 TIGRFAM TIGR03252 TIGR03252: uncharacterized HhH-GPD family protein 8 193 1.5E-88 T 28-03-2018 IPR017658 Conserved hypothetical protein CHP03252, HhH-GPD CNX65_RS14525 04e9ef97503a1bbef5da39c0d8bcc9c2 193 Gene3D G3DSA:1.10.340.30 19 143 1.1E-11 T 28-03-2018 CNX65_RS14525 04e9ef97503a1bbef5da39c0d8bcc9c2 193 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 31 143 1.7E-13 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CNX65_RS34510 47271bc51c6ae595c1edbaff9aa75fe4 469 SUPERFAMILY SSF53187 380 463 3.43E-45 T 28-03-2018 CNX65_RS34510 47271bc51c6ae595c1edbaff9aa75fe4 469 SUPERFAMILY SSF53187 13 206 3.43E-45 T 28-03-2018 CNX65_RS34510 47271bc51c6ae595c1edbaff9aa75fe4 469 Gene3D G3DSA:3.30.70.360 210 376 1.9E-33 T 28-03-2018 CNX65_RS34510 47271bc51c6ae595c1edbaff9aa75fe4 469 Gene3D G3DSA:3.40.630.10 9 209 1.3E-23 T 28-03-2018 CNX65_RS34510 47271bc51c6ae595c1edbaff9aa75fe4 469 Pfam PF07687 Peptidase dimerisation domain 204 363 5.4E-12 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS34510 47271bc51c6ae595c1edbaff9aa75fe4 469 Pfam PF01546 Peptidase family M20/M25/M40 92 463 3.4E-22 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 SMART SM00633 82 338 1.2E-129 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 264 274 - T 28-03-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 Gene3D G3DSA:3.20.20.80 26 349 7.6E-69 T 28-03-2018 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 Pfam PF00553 Cellulose binding domain 366 452 1.0E-17 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 200 211 1.4E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 230 242 1.4E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 113 125 1.4E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 155 166 1.4E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 SUPERFAMILY SSF51445 39 340 9.15E-107 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 SMART SM00637 364 454 8.8E-26 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 SUPERFAMILY SSF49384 360 454 6.98E-22 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 Pfam PF00331 Glycosyl hydrolase family 10 43 336 1.3E-105 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS13135 5358be90f0ffdeab83f9cd7489bda52c 457 Gene3D G3DSA:2.60.40.290 352 456 4.3E-24 T 28-03-2018 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 SMART SM00354 6 76 1.4E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 ProSitePatterns PS00356 LacI-type HTH domain signature. 9 27 - T 28-03-2018 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 Gene3D G3DSA:3.40.50.2300 175 334 3.0E-46 T 28-03-2018 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 SUPERFAMILY SSF47413 6 65 8.44E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 8 18 1.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 18 28 1.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 SUPERFAMILY SSF53822 66 333 8.88E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 Pfam PF13377 Periplasmic binding protein-like domain 169 331 7.4E-41 T 28-03-2018 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 Gene3D G3DSA:3.40.50.2300 61 174 5.5E-28 T 28-03-2018 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 Gene3D G3DSA:1.10.260.40 7 60 2.4E-21 T 28-03-2018 CNX65_RS12225 dc3e68d2393db25ce8c9bfa36623f4cf 379 Pfam PF00356 Bacterial regulatory proteins, lacI family 8 51 4.2E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 SMART SM00304 172 225 2.0E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 Gene3D G3DSA:3.30.565.10 299 457 5.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 Gene3D G3DSA:1.10.287.130 216 293 3.1E-11 T 28-03-2018 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 SUPERFAMILY SSF158472 172 222 4.32E-6 T 28-03-2018 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 SMART SM00388 226 297 1.7E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 SUPERFAMILY SSF55874 299 451 1.57E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 SMART SM00387 337 451 1.1E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 Pfam PF00672 HAMP domain 172 221 8.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 411 429 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 392 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 448 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 PRINTS PR00344 Bacterial sensor protein C-terminal signature 396 406 5.0E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 337 449 1.1E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 296 6.6E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS13345 9fec0c1902836cad0b926b3c730d94e7 502 SUPERFAMILY SSF47384 209 295 1.49E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24285 1f7718ecb2ac253b7df3d10ff7b418c7 495 PIRSF PIRSF002741 48 481 3.7E-47 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS24285 1f7718ecb2ac253b7df3d10ff7b418c7 495 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 414 2.6E-52 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS24285 1f7718ecb2ac253b7df3d10ff7b418c7 495 SUPERFAMILY SSF53850 31 482 8.81E-80 T 28-03-2018 CNX65_RS24285 1f7718ecb2ac253b7df3d10ff7b418c7 495 Gene3D G3DSA:3.90.76.10 56 179 5.3E-21 T 28-03-2018 CNX65_RS24285 1f7718ecb2ac253b7df3d10ff7b418c7 495 Gene3D G3DSA:3.40.190.10 180 272 7.8E-20 T 28-03-2018 CNX65_RS24285 1f7718ecb2ac253b7df3d10ff7b418c7 495 Gene3D G3DSA:3.10.105.10 273 466 3.3E-32 T 28-03-2018 CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 Gene3D G3DSA:3.40.50.720 1 240 9.6E-62 T 28-03-2018 CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 169 0.0084 T 28-03-2018 CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.1E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.1E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 2.1E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 2.1E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 2.1E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 236 1.1E-49 T 28-03-2018 CNX65_RS23815 04cd1464a7521dbad080f5da0ca94cc1 241 SUPERFAMILY SSF51735 5 237 8.54E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26120 5cd44d60e15c19405f277208e0011756 139 Pfam PF01029 NusB family 6 129 1.4E-34 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CNX65_RS26120 5cd44d60e15c19405f277208e0011756 139 Hamap MF_00073 N utilization substance protein B homolog [nusB]. 2 133 22.251 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CNX65_RS26120 5cd44d60e15c19405f277208e0011756 139 Gene3D G3DSA:1.10.940.10 1 137 4.2E-42 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CNX65_RS26120 5cd44d60e15c19405f277208e0011756 139 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 4 129 7.3E-40 T 28-03-2018 IPR011605 NusB antitermination factor GO:0006353 CNX65_RS26120 5cd44d60e15c19405f277208e0011756 139 SUPERFAMILY SSF48013 4 128 7.98E-39 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CNX65_RS15135 463b1bab5a2f6f5b74394156195420f7 387 Pfam PF07730 Histidine kinase 181 248 1.5E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS15135 463b1bab5a2f6f5b74394156195420f7 387 SUPERFAMILY SSF55874 291 385 9.49E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS15135 463b1bab5a2f6f5b74394156195420f7 387 Gene3D G3DSA:3.30.565.10 250 385 1.9E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 Gene3D G3DSA:3.40.50.620 388 603 5.7E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 Gene3D G3DSA:3.90.740.10 209 387 1.6E-65 T 28-03-2018 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 9 1030 13.915 T 28-03-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 SUPERFAMILY SSF52374 11 208 1.64E-123 T 28-03-2018 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 SUPERFAMILY SSF52374 399 645 1.64E-123 T 28-03-2018 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 Gene3D G3DSA:3.40.50.620 41 207 2.1E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 Gene3D G3DSA:1.10.730.10 604 825 3.6E-48 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 SUPERFAMILY SSF50677 212 399 1.78E-52 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 11 840 8.9E-249 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 58 69 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 51 62 3.3E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 526 539 3.3E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 566 575 3.3E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 231 254 3.3E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 397 412 3.3E-30 T 28-03-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 24 641 6.0E-186 T 28-03-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 Pfam PF08264 Anticodon-binding domain of tRNA 692 829 6.9E-23 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CNX65_RS28195 0f8a9db5935b5f7a9ed1cb8ede7daa18 1037 SUPERFAMILY SSF47323 662 891 6.54E-43 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 SUPERFAMILY SSF56112 258 468 6.05E-34 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 391 403 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 Pfam PF16918 Protein kinase G tetratricopeptide repeat 709 824 7.9E-31 T 28-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 SUPERFAMILY SSF48452 708 832 1.04E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 Gene3D G3DSA:1.25.40.10 590 842 7.9E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 SMART SM00220 267 517 2.5E-12 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 Pfam PF16919 Protein kinase G rubredoxin domain 199 266 7.2E-10 T 28-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 Pfam PF00069 Protein kinase domain 268 466 2.0E-21 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 Gene3D G3DSA:1.10.510.10 350 538 1.7E-18 T 28-03-2018 CNX65_RS12815 1cbbd5c2f64454815e61b383eb98ad01 898 Gene3D G3DSA:3.30.200.20 255 349 5.4E-13 T 28-03-2018 CNX65_RS15575 59f87c9a34e2fdaf0c8669627d78a126 547 SUPERFAMILY SSF53850 47 545 9.77E-99 T 28-03-2018 CNX65_RS15575 59f87c9a34e2fdaf0c8669627d78a126 547 Gene3D G3DSA:3.40.190.10 190 306 2.5E-26 T 28-03-2018 CNX65_RS15575 59f87c9a34e2fdaf0c8669627d78a126 547 PIRSF PIRSF002741 18 539 1.4E-76 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS15575 59f87c9a34e2fdaf0c8669627d78a126 547 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 92 446 1.6E-75 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS15575 59f87c9a34e2fdaf0c8669627d78a126 547 Gene3D G3DSA:3.90.76.10 65 189 2.0E-25 T 28-03-2018 CNX65_RS15575 59f87c9a34e2fdaf0c8669627d78a126 547 Gene3D G3DSA:3.10.105.10 307 491 6.3E-39 T 28-03-2018 CNX65_RS10655 82c2054b0ff3812dfc2b5e94f203ef01 279 Pfam PF13560 Helix-turn-helix domain 13 70 6.6E-12 T 28-03-2018 CNX65_RS10655 82c2054b0ff3812dfc2b5e94f203ef01 279 Gene3D G3DSA:1.10.10.60 1 36 8.2E-7 T 28-03-2018 CNX65_RS10655 82c2054b0ff3812dfc2b5e94f203ef01 279 SMART SM00530 17 72 4.1E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS10655 82c2054b0ff3812dfc2b5e94f203ef01 279 Gene3D G3DSA:3.30.1190.10 37 91 0.0018 T 28-03-2018 CNX65_RS10655 82c2054b0ff3812dfc2b5e94f203ef01 279 SUPERFAMILY SSF47413 12 68 2.95E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS19525 5067aaceae6cbd3758eba29a7db79152 493 Pfam PF00743 Flavin-binding monooxygenase-like 9 214 4.2E-14 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS19525 5067aaceae6cbd3758eba29a7db79152 493 SUPERFAMILY SSF51905 295 411 6.58E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19525 5067aaceae6cbd3758eba29a7db79152 493 SUPERFAMILY SSF51905 9 228 6.58E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19525 5067aaceae6cbd3758eba29a7db79152 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 174 192 5.3E-5 T 28-03-2018 CNX65_RS19525 5067aaceae6cbd3758eba29a7db79152 493 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 5.3E-5 T 28-03-2018 CNX65_RS19525 5067aaceae6cbd3758eba29a7db79152 493 Gene3D G3DSA:3.50.50.60 164 488 1.4E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19525 5067aaceae6cbd3758eba29a7db79152 493 Gene3D G3DSA:3.50.50.60 7 163 5.6E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 SMART SM00354 8 78 9.6E-20 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 ProSitePatterns PS01081 TetR-type HTH domain signature. 5 35 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 Gene3D G3DSA:3.40.50.2300 60 186 1.7E-26 T 28-03-2018 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 10 55 5.3E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 28-03-2018 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 Pfam PF13377 Periplasmic binding protein-like domain 180 339 2.9E-36 T 28-03-2018 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 Gene3D G3DSA:1.10.260.40 8 59 5.1E-18 T 28-03-2018 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 Gene3D G3DSA:3.40.50.2300 187 316 5.2E-39 T 28-03-2018 CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 SUPERFAMILY SSF53822 82 342 6.67E-55 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS20670 296ce44c3a6215524078cd02e787096b 344 SUPERFAMILY SSF47413 8 64 7.41E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS27370 5fbbb76d540c2e0569bd606feea14a38 185 Gene3D G3DSA:1.10.3450.10 2 163 5.4E-47 T 28-03-2018 IPR023203 TTHA0068-like domain CNX65_RS27370 5fbbb76d540c2e0569bd606feea14a38 185 Pfam PF03745 Domain of unknown function (DUF309) 49 107 1.2E-21 T 28-03-2018 IPR005500 Protein of unknown function DUF309 CNX65_RS27370 5fbbb76d540c2e0569bd606feea14a38 185 SUPERFAMILY SSF140663 31 138 6.54E-29 T 28-03-2018 IPR023203 TTHA0068-like domain CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 SUPERFAMILY SSF50494 13 236 2.16E-65 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 Gene3D G3DSA:2.40.10.10 53 114 1.0E-15 T 28-03-2018 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 SMART SM00020 19 237 1.0E-63 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 195 206 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 Gene3D G3DSA:2.40.10.10 20 52 1.2E-13 T 28-03-2018 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 104 118 2.9E-11 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 194 206 2.9E-11 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 48 63 2.9E-11 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 Gene3D G3DSA:2.40.10.10 115 237 9.2E-37 T 28-03-2018 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 Pfam PF00089 Trypsin 27 236 2.3E-50 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS28790 909009276e4291b8bf92614ce5285d1a 237 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 58 63 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 475 488 1.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 429 1.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 433 443 1.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 469 1.6E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 375 490 3.1E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 SUPERFAMILY SSF55874 322 493 4.19E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 SMART SM00387 374 491 5.7E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 Gene3D G3DSA:1.10.287.130 260 329 1.2E-17 T 28-03-2018 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 Pfam PF00512 His Kinase A (phospho-acceptor) domain 271 332 4.2E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 SMART SM00388 270 333 1.3E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 Gene3D G3DSA:3.30.565.10 336 499 4.3E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 Pfam PF00672 HAMP domain 218 266 8.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 SUPERFAMILY SSF47384 253 333 2.55E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 SMART SM00304 217 269 6.0E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS24325 dd62a6f4e60fc79c0fddadc83ef53b76 515 SUPERFAMILY SSF158472 219 266 7.19E-8 T 28-03-2018 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 PIRSF PIRSF006431 1 308 7.9E-97 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 Pfam PF00561 alpha/beta hydrolase fold 32 192 8.5E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 Gene3D G3DSA:3.40.50.1820 1 308 1.8E-48 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 6 301 4.8E-78 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 1.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 122 135 1.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 PRINTS PR00111 Alpha/beta hydrolase fold signature 108 121 1.3E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 SUPERFAMILY SSF53474 4 300 8.58E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 60 71 4.4E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 34 42 4.4E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS24485 852470c80cb8c8e03145ecf09328e918 308 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 108 122 4.4E-13 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 126 251 1.3E-54 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 Gene3D G3DSA:2.30.30.30 120 196 1.0E-29 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 SMART SM01382 125 253 4.0E-88 T 28-03-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 272 4.5E-125 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 SUPERFAMILY SSF50104 127 269 2.35E-55 T 28-03-2018 IPR008991 Translation protein SH3-like domain CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 PIRSF PIRSF002158 4 274 5.6E-94 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 Gene3D G3DSA:4.10.950.10 198 272 4.1E-29 T 28-03-2018 IPR014726 Ribosomal protein L2, domain 3 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 272 47.121 T 28-03-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 SMART SM01383 42 119 1.8E-40 T 28-03-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 SUPERFAMILY SSF50249 3 126 1.17E-48 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 Gene3D G3DSA:2.40.50.140 1 115 2.9E-45 T 28-03-2018 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 ProSitePatterns PS00467 Ribosomal protein L2 signature. 219 230 - T 28-03-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32435 81dc3c8f97b940f19246f8d02b393fc7 277 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.5E-32 T 28-03-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS26515 7678094d507a3ee00a1a47be3e781546 298 SUPERFAMILY SSF159659 6 266 1.12E-82 T 28-03-2018 CNX65_RS26515 7678094d507a3ee00a1a47be3e781546 298 Gene3D G3DSA:1.10.287.100 225 264 3.0E-15 T 28-03-2018 CNX65_RS26515 7678094d507a3ee00a1a47be3e781546 298 Gene3D G3DSA:1.10.1400.10 8 163 9.3E-4 T 28-03-2018 CNX65_RS26515 7678094d507a3ee00a1a47be3e781546 298 Pfam PF09754 PAC2 family 27 242 7.0E-42 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CNX65_RS26515 7678094d507a3ee00a1a47be3e781546 298 PIRSF PIRSF028754 6 298 7.8E-94 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 6 276 2.0E-10 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 Gene3D G3DSA:3.30.420.40 1 271 2.2E-49 T 28-03-2018 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 TIGRFAM TIGR01234 L-ribulokinase: ribulokinase 7 535 7.9E-248 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 Hamap MF_00520 Ribulokinase [araB]. 4 543 47.934 T 28-03-2018 IPR005929 Ribulokinase GO:0005524|GO:0008741|GO:0019569 KEGG: 00040+2.7.1.16 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 289 486 5.5E-42 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 SUPERFAMILY SSF53067 282 532 1.97E-58 T 28-03-2018 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 SUPERFAMILY SSF53067 6 280 4.53E-36 T 28-03-2018 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 PIRSF PIRSF000538 4 534 2.2E-60 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS09295 a126712ab34b565b6bb300b1e2e9c0a7 554 Gene3D G3DSA:3.30.420.40 282 545 4.7E-57 T 28-03-2018 CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 228 238 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 Pfam PF00082 Subtilase family 165 523 1.6E-40 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 Gene3D G3DSA:3.40.50.200 142 573 1.1E-64 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 PRINTS PR00723 Subtilisin serine protease family (S8) signature 475 491 8.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 PRINTS PR00723 Subtilisin serine protease family (S8) signature 164 183 8.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 PRINTS PR00723 Subtilisin serine protease family (S8) signature 224 237 8.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 SUPERFAMILY SSF52743 147 343 1.83E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 SUPERFAMILY SSF52743 370 569 1.83E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 476 486 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS05215 8db6547880326c7563684fbe1d09b583 575 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 169 180 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS23945 566a4e80d8ba83adc88ec0a1dddff876 377 SUPERFAMILY SSF110738 7 375 4.45E-103 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS23945 566a4e80d8ba83adc88ec0a1dddff876 377 PIRSF PIRSF006078 6 376 7.4E-115 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS23945 566a4e80d8ba83adc88ec0a1dddff876 377 Pfam PF02595 Glycerate kinase family 8 375 3.4E-120 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS23945 566a4e80d8ba83adc88ec0a1dddff876 377 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 8 375 7.6E-108 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS23945 566a4e80d8ba83adc88ec0a1dddff876 377 Gene3D G3DSA:3.90.1510.10 45 278 2.9E-76 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CNX65_RS03855 bcec4000288c3d0945829a737f75a5ee 193 TIGRFAM TIGR00624 tag: DNA-3-methyladenine glycosylase I 3 178 4.1E-74 T 28-03-2018 IPR004597 DNA-3-methyladenine glycosylase I GO:0006284|GO:0008725 CNX65_RS03855 bcec4000288c3d0945829a737f75a5ee 193 Pfam PF03352 Methyladenine glycosylase 7 178 6.0E-67 T 28-03-2018 IPR005019 Methyladenine glycosylase GO:0006284|GO:0008725 CNX65_RS03855 bcec4000288c3d0945829a737f75a5ee 193 SUPERFAMILY SSF48150 3 181 2.62E-68 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS03855 bcec4000288c3d0945829a737f75a5ee 193 Gene3D G3DSA:1.10.340.30 2 179 2.1E-74 T 28-03-2018 CNX65_RS15040 65b256faed0bc26ccf458b1d78b25351 361 SMART SM00418 290 360 2.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS15040 65b256faed0bc26ccf458b1d78b25351 361 Gene3D G3DSA:1.10.10.10 156 361 6.9E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15040 65b256faed0bc26ccf458b1d78b25351 361 SUPERFAMILY SSF46785 294 360 4.99E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15040 65b256faed0bc26ccf458b1d78b25351 361 Pfam PF12840 Helix-turn-helix domain 294 343 2.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26750 74211ad1a7c56d6dde4afc382aafbf53 100 Pfam PF03551 Transcriptional regulator PadR-like family 16 71 6.1E-7 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS26750 74211ad1a7c56d6dde4afc382aafbf53 100 SUPERFAMILY SSF46785 4 86 7.86E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26750 74211ad1a7c56d6dde4afc382aafbf53 100 Gene3D G3DSA:1.10.10.10 1 99 6.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08640 f6cbc9e973003dc6464b93743a31a843 364 Gene3D G3DSA:3.30.360.10 145 342 4.8E-29 T 28-03-2018 CNX65_RS08640 f6cbc9e973003dc6464b93743a31a843 364 SUPERFAMILY SSF51735 8 159 8.92E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS08640 f6cbc9e973003dc6464b93743a31a843 364 Gene3D G3DSA:3.40.50.720 5 144 4.8E-43 T 28-03-2018 CNX65_RS08640 f6cbc9e973003dc6464b93743a31a843 364 SUPERFAMILY SSF55347 137 270 7.19E-16 T 28-03-2018 CNX65_RS08640 f6cbc9e973003dc6464b93743a31a843 364 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 13 130 2.1E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS15755 6df4fb07cc93765c04e0478ae6431e67 533 Gene3D G3DSA:3.40.640.10 182 406 1.1E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS15755 6df4fb07cc93765c04e0478ae6431e67 533 SUPERFAMILY SSF53383 127 520 5.19E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS15755 6df4fb07cc93765c04e0478ae6431e67 533 Gene3D G3DSA:3.90.1150.10 407 522 3.8E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15755 6df4fb07cc93765c04e0478ae6431e67 533 Pfam PF00155 Aminotransferase class I and II 168 514 2.7E-39 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS00290 aeae24311f12936adb42ea3c4e903644 1171 Gene3D G3DSA:1.20.1170.10 422 664 7.1E-7 T 28-03-2018 CNX65_RS00290 aeae24311f12936adb42ea3c4e903644 1171 Pfam PF00535 Glycosyl transferase family 2 847 974 9.5E-15 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS00290 aeae24311f12936adb42ea3c4e903644 1171 SUPERFAMILY SSF53448 843 1056 6.56E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS00290 aeae24311f12936adb42ea3c4e903644 1171 Gene3D G3DSA:3.40.50.150 14 226 1.2E-25 T 28-03-2018 CNX65_RS00290 aeae24311f12936adb42ea3c4e903644 1171 Pfam PF08241 Methyltransferase domain 65 162 2.5E-11 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS00290 aeae24311f12936adb42ea3c4e903644 1171 SUPERFAMILY SSF53335 57 227 3.29E-30 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS00290 aeae24311f12936adb42ea3c4e903644 1171 Gene3D G3DSA:3.90.550.10 818 1075 4.4E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08870 24f8dda09e2bcdca1db9a7d53e4b93f7 242 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 5 237 3.0E-40 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CNX65_RS08870 24f8dda09e2bcdca1db9a7d53e4b93f7 242 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 7 236 3.2E-64 T 28-03-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 CNX65_RS08870 24f8dda09e2bcdca1db9a7d53e4b93f7 242 Gene3D G3DSA:3.40.50.2300 67 242 4.4E-21 T 28-03-2018 CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 SMART SM00344 4 109 1.7E-33 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 SUPERFAMILY SSF54909 66 137 1.01E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 Gene3D G3DSA:3.30.70.920 54 143 5.6E-18 T 28-03-2018 CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 Gene3D G3DSA:1.10.10.10 4 53 2.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 Pfam PF01037 Lrp/AsnC ligand binding domain 69 135 2.4E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 1.9E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 1.9E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 1.9E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 Pfam PF13404 AsnC-type helix-turn-helix domain 4 44 4.3E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS04485 d0310a291b164d5b89296ea156a0e999 154 SUPERFAMILY SSF46785 4 62 1.65E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 98 109 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 Pfam PF12838 4Fe-4S dicluster domain 52 110 3.5E-11 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 53 64 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 Gene3D G3DSA:3.30.70.20 101 164 2.2E-7 T 28-03-2018 CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 146 27.072 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 SUPERFAMILY SSF54862 26 141 3.14E-25 T 28-03-2018 CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 Gene3D G3DSA:3.30.70.20 43 100 1.6E-15 T 28-03-2018 CNX65_RS32890 9b108a390bf7b18b3df6b857aa4ec335 188 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 9 136 2.9E-40 T 28-03-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS09780 d17480b0705f7997616f937320730ff4 268 SUPERFAMILY SSF48498 148 245 8.9E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS09780 d17480b0705f7997616f937320730ff4 268 Gene3D G3DSA:1.10.260.40 111 131 7.5E-4 T 28-03-2018 CNX65_RS09780 d17480b0705f7997616f937320730ff4 268 Gene3D G3DSA:1.10.357.10 132 253 1.1E-4 T 28-03-2018 CNX65_RS09780 d17480b0705f7997616f937320730ff4 268 Pfam PF00440 Bacterial regulatory proteins, tetR family 83 128 3.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS09780 d17480b0705f7997616f937320730ff4 268 Gene3D G3DSA:1.10.10.60 67 110 2.4E-13 T 28-03-2018 CNX65_RS09780 d17480b0705f7997616f937320730ff4 268 SUPERFAMILY SSF46689 69 145 4.21E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS11565 a9ce0a86fe941a3ffa3ecf4d80bae2b4 323 SUPERFAMILY SSF52540 28 297 1.02E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11565 a9ce0a86fe941a3ffa3ecf4d80bae2b4 323 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 51 180 3.3E-57 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CNX65_RS11565 a9ce0a86fe941a3ffa3ecf4d80bae2b4 323 Gene3D G3DSA:1.10.8.300 212 320 2.9E-23 T 28-03-2018 CNX65_RS11565 a9ce0a86fe941a3ffa3ecf4d80bae2b4 323 PIRSF PIRSF002849 2 323 2.1E-111 T 28-03-2018 CNX65_RS11565 a9ce0a86fe941a3ffa3ecf4d80bae2b4 323 Gene3D G3DSA:3.40.50.300 32 198 1.1E-24 T 28-03-2018 CNX65_RS03740 c64d7027c5a20cca960fb7366f42699a 100 SUPERFAMILY SSF54909 1 82 1.39E-10 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS03740 c64d7027c5a20cca960fb7366f42699a 100 Gene3D G3DSA:3.30.70.1060 1 84 1.7E-8 T 28-03-2018 CNX65_RS03740 c64d7027c5a20cca960fb7366f42699a 100 Pfam PF03795 YCII-related domain 1 49 4.8E-6 T 28-03-2018 IPR005545 YCII-related CNX65_RS34630 a8403b9fa37389149310d66931dd11ca 402 SMART SM00387 306 401 0.0064 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34630 a8403b9fa37389149310d66931dd11ca 402 SUPERFAMILY SSF55874 286 399 4.11E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34630 a8403b9fa37389149310d66931dd11ca 402 Pfam PF07730 Histidine kinase 197 262 6.8E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS34630 a8403b9fa37389149310d66931dd11ca 402 Gene3D G3DSA:3.30.565.10 275 401 2.0E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 SUPERFAMILY SSF48008 79 211 6.28E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 SMART SM00345 15 73 6.0E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 Gene3D G3DSA:1.20.120.530 70 218 2.0E-30 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 SUPERFAMILY SSF46785 8 99 5.59E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 SMART SM00895 83 209 3.7E-18 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 65 7.0E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 Gene3D G3DSA:1.10.10.10 1 69 2.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12515 ed219803be7aa48fc166f6091d96525c 224 Pfam PF07729 FCD domain 83 208 2.8E-23 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 Pfam PF13377 Periplasmic binding protein-like domain 189 350 1.1E-41 T 28-03-2018 CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 SUPERFAMILY SSF53822 126 351 3.77E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 SMART SM00354 3 70 3.4E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 SUPERFAMILY SSF47413 2 49 1.69E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 Gene3D G3DSA:3.40.50.2300 59 187 3.3E-16 T 28-03-2018 CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 Gene3D G3DSA:3.40.50.2300 188 353 2.7E-54 T 28-03-2018 CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 49 8.1E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09105 a83f85a48c3eb9272bcbe6496daf3cfe 354 Gene3D G3DSA:1.10.260.40 2 58 7.6E-16 T 28-03-2018 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 13 181 1.0E-24 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 Pfam PF01968 Hydantoinase/oxoprolinase 200 508 6.0E-68 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 SUPERFAMILY SSF53067 258 306 1.05E-9 T 28-03-2018 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 SUPERFAMILY SSF53067 339 366 1.05E-9 T 28-03-2018 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 SUPERFAMILY SSF53067 409 504 1.05E-9 T 28-03-2018 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 SUPERFAMILY SSF53067 14 88 1.05E-9 T 28-03-2018 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 Gene3D G3DSA:3.30.420.150 259 653 8.8E-7 T 28-03-2018 CNX65_RS17155 605e5fb7faa48709594079dc69bba986 720 Gene3D G3DSA:3.30.420.40 6 127 1.9E-9 T 28-03-2018 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 428 437 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00385 P450 superfamily signature 426 435 4.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00385 P450 superfamily signature 435 446 4.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00385 P450 superfamily signature 351 362 4.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00385 P450 superfamily signature 299 316 4.4E-8 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 Gene3D G3DSA:1.10.630.10 48 486 7.7E-92 T 28-03-2018 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 Pfam PF00067 Cytochrome P450 51 476 6.0E-60 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 SUPERFAMILY SSF48264 50 486 3.01E-88 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00463 E-class P450 group I signature 390 414 5.5E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00463 E-class P450 group I signature 435 458 5.5E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00463 E-class P450 group I signature 288 305 5.5E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00463 E-class P450 group I signature 308 334 5.5E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00463 E-class P450 group I signature 77 96 5.5E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS24005 cafda541bba91e720f7a62f768db7ff3 486 PRINTS PR00463 E-class P450 group I signature 425 435 5.5E-22 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS07355 7f8898f3b13d33b8c453c0b59655ecb9 274 SUPERFAMILY SSF51735 4 233 2.65E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07355 7f8898f3b13d33b8c453c0b59655ecb9 274 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 167 3.3E-24 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS07355 7f8898f3b13d33b8c453c0b59655ecb9 274 Gene3D G3DSA:3.40.50.720 2 230 1.4E-39 T 28-03-2018 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 Pfam PF12833 Helix-turn-helix domain 235 313 2.3E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 Gene3D G3DSA:1.10.10.60 232 271 1.6E-13 T 28-03-2018 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 SUPERFAMILY SSF46689 215 263 1.12E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 SUPERFAMILY SSF52317 1 196 8.81E-38 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 SUPERFAMILY SSF46689 266 315 8.08E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 SMART SM00342 229 312 8.4E-30 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 266 308 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 Pfam PF01965 DJ-1/PfpI family 2 175 3.4E-12 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 Gene3D G3DSA:1.10.10.60 272 317 1.3E-13 T 28-03-2018 CNX65_RS21610 f45ab187ea869d8628f1c934ffa0c263 320 Gene3D G3DSA:3.40.50.880 1 231 9.3E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 Gene3D G3DSA:1.20.1250.20 269 517 3.6E-30 T 28-03-2018 CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 SUPERFAMILY SSF103473 265 437 1.1E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 SUPERFAMILY SSF103473 481 512 1.1E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 SUPERFAMILY SSF103473 17 208 1.1E-63 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 Pfam PF07690 Major Facilitator Superfamily 31 427 5.4E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 Gene3D G3DSA:1.20.1250.20 17 214 3.4E-33 T 28-03-2018 CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 PRINTS PR01036 Tetracycline resistance protein TetB signature 151 175 8.1E-12 T 28-03-2018 CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 PRINTS PR01036 Tetracycline resistance protein TetB signature 418 437 8.1E-12 T 28-03-2018 CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 PRINTS PR01036 Tetracycline resistance protein TetB signature 121 141 8.1E-12 T 28-03-2018 CNX65_RS12780 dee666b31737965a91ab0950ddff475b 551 PRINTS PR01036 Tetracycline resistance protein TetB signature 30 54 8.1E-12 T 28-03-2018 CNX65_RS06660 48f31b4ae37e66fc6e636fc4c700f11a 275 Gene3D G3DSA:3.40.50.720 2 63 0.013 T 28-03-2018 CNX65_RS06660 48f31b4ae37e66fc6e636fc4c700f11a 275 SUPERFAMILY SSF51735 3 243 2.73E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06660 48f31b4ae37e66fc6e636fc4c700f11a 275 Gene3D G3DSA:3.40.50.720 71 271 7.3E-11 T 28-03-2018 CNX65_RS23490 83fa3996445e3ccb10db04cb47b0b3dc 564 Gene3D G3DSA:3.40.190.10 186 325 5.4E-30 T 28-03-2018 CNX65_RS23490 83fa3996445e3ccb10db04cb47b0b3dc 564 Gene3D G3DSA:3.10.105.10 326 530 2.8E-50 T 28-03-2018 CNX65_RS23490 83fa3996445e3ccb10db04cb47b0b3dc 564 Gene3D G3DSA:3.90.76.10 64 185 1.3E-23 T 28-03-2018 CNX65_RS23490 83fa3996445e3ccb10db04cb47b0b3dc 564 PIRSF PIRSF002741 2 555 4.0E-72 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS23490 83fa3996445e3ccb10db04cb47b0b3dc 564 SUPERFAMILY SSF53850 38 545 7.96E-103 T 28-03-2018 CNX65_RS23490 83fa3996445e3ccb10db04cb47b0b3dc 564 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 91 472 5.8E-77 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 Gene3D G3DSA:2.40.10.10 118 233 4.0E-38 T 28-03-2018 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 SUPERFAMILY SSF50494 7 240 7.45E-57 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 Gene3D G3DSA:2.30.42.10 234 317 1.6E-14 T 28-03-2018 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 Pfam PF13365 Trypsin-like peptidase domain 43 187 1.1E-35 T 28-03-2018 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 Gene3D G3DSA:2.40.10.10 17 117 1.3E-29 T 28-03-2018 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 SMART SM00228 232 303 3.3E-8 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 SUPERFAMILY SSF50156 202 304 9.05E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 Pfam PF13180 PDZ domain 233 302 1.3E-15 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 PRINTS PR00834 HtrA/DegQ protease family signature 76 96 6.4E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 PRINTS PR00834 HtrA/DegQ protease family signature 261 273 6.4E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 PRINTS PR00834 HtrA/DegQ protease family signature 117 141 6.4E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 PRINTS PR00834 HtrA/DegQ protease family signature 158 175 6.4E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 PRINTS PR00834 HtrA/DegQ protease family signature 180 197 6.4E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03085 224975b7e37ca3fc0ebc48987f191751 317 PRINTS PR00834 HtrA/DegQ protease family signature 52 64 6.4E-49 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 Gene3D G3DSA:3.10.150.10 128 253 1.8E-33 T 28-03-2018 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 Gene3D G3DSA:3.10.150.10 1 126 1.4E-31 T 28-03-2018 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 132 249 2.2E-30 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 251 361 2.7E-32 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 SUPERFAMILY SSF55979 251 376 1.02E-29 T 28-03-2018 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 SMART SM00480 17 372 1.7E-118 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 SUPERFAMILY SSF55979 1 123 2.27E-22 T 28-03-2018 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 376 1.3E-98 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 Gene3D G3DSA:3.10.150.10 254 376 7.4E-34 T 28-03-2018 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 SUPERFAMILY SSF55979 132 250 1.19E-21 T 28-03-2018 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 123 8.0E-32 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS00010 e3ab4b87784052c566e89fd055781148 378 PIRSF PIRSF000804 1 377 1.4E-99 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS16430 81234294c5783183ea9a4d494ce3389d 698 Gene3D G3DSA:2.60.40.10 98 175 2.9E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS16430 81234294c5783183ea9a4d494ce3389d 698 Gene3D G3DSA:2.60.40.290 592 696 2.5E-30 T 28-03-2018 CNX65_RS16430 81234294c5783183ea9a4d494ce3389d 698 Pfam PF08757 CotH kinase protein 226 583 2.0E-65 T 28-03-2018 IPR014867 Spore coat protein CotH CNX65_RS16430 81234294c5783183ea9a4d494ce3389d 698 Pfam PF00553 Cellulose binding domain 602 690 6.6E-25 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16430 81234294c5783183ea9a4d494ce3389d 698 SUPERFAMILY SSF49384 596 693 1.74E-27 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS16430 81234294c5783183ea9a4d494ce3389d 698 SMART SM00637 602 695 1.3E-36 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16430 81234294c5783183ea9a4d494ce3389d 698 Pfam PF13290 Chitobiase/beta-hexosaminidase C-terminal domain 98 156 3.3E-12 T 28-03-2018 CNX65_RS11905 29ade345b59da7c1f9ef02cce9656842 101 Pfam PF06289 Flagellar protein (FlbD) 2 58 3.1E-21 T 28-03-2018 IPR009384 Flagellar CNX65_RS14385 a15cf044319bf8ceb058dd23231b3def 311 SUPERFAMILY SSF161098 44 296 5.51E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14385 a15cf044319bf8ceb058dd23231b3def 311 Gene3D G3DSA:1.10.3720.10 41 295 2.0E-37 T 28-03-2018 CNX65_RS14385 a15cf044319bf8ceb058dd23231b3def 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 290 9.4E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 7 194 2.3E-17 T 28-03-2018 IPR003111 Lon, substrate-binding domain CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 SMART SM00464 6 197 3.3E-16 T 28-03-2018 IPR003111 Lon, substrate-binding domain CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 708 727 3.5E-49 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 731 749 3.5E-49 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 601 617 3.5E-49 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 678 697 3.5E-49 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 361 380 3.5E-49 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Gene3D G3DSA:3.40.50.300 310 496 4.0E-30 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 TIGRFAM TIGR00763 lon: endopeptidase La 8 775 1.2E-238 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 SUPERFAMILY SSF88697 7 194 7.21E-19 T 28-03-2018 IPR015947 PUA-like domain CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Gene3D G3DSA:1.10.8.60 497 582 1.2E-25 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 SMART SM00382 353 506 3.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 PIRSF PIRSF001174 2 780 6.4E-243 T 28-03-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 SUPERFAMILY SSF54211 601 775 2.39E-48 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Hamap MF_01973 Lon protease [lon]. 7 777 58.411 T 28-03-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Gene3D G3DSA:3.30.230.10 583 787 1.0E-59 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Gene3D G3DSA:2.30.130.40 4 117 5.2E-13 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Gene3D G3DSA:1.10.4060.10 118 202 3.3E-6 T 28-03-2018 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 SUPERFAMILY SSF52540 305 561 1.91E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 576 777 1.3E-75 T 28-03-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 358 493 4.4E-20 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS28815 2e8f8f97a0ac248f049016e058c80475 787 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 681 689 - T 28-03-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 PRINTS PR00944 Copper ion binding protein signature 3 15 2.4E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 PRINTS PR00944 Copper ion binding protein signature 15 28 2.4E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 PRINTS PR00944 Copper ion binding protein signature 28 41 2.4E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 PRINTS PR00944 Copper ion binding protein signature 53 66 2.4E-6 T 28-03-2018 IPR000428 Copper ion binding protein GO:0005507|GO:0006825 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 SUPERFAMILY SSF55008 2 67 2.23E-17 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 37 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 Pfam PF00403 Heavy-metal-associated domain 5 65 5.9E-14 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CNX65_RS33515 6f219bb26be2d32e92d9c6c691bd085b 68 Gene3D G3DSA:3.30.70.100 1 67 2.0E-18 T 28-03-2018 CNX65_RS04930 11559f899bbabb27f1aeb66590da7159 375 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 221 350 3.2E-16 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS04930 11559f899bbabb27f1aeb66590da7159 375 Gene3D G3DSA:2.40.110.10 101 200 5.0E-17 T 28-03-2018 CNX65_RS04930 11559f899bbabb27f1aeb66590da7159 375 SUPERFAMILY SSF47203 219 368 6.93E-17 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS04930 11559f899bbabb27f1aeb66590da7159 375 Gene3D G3DSA:1.20.140.10 201 370 2.9E-22 T 28-03-2018 CNX65_RS04930 11559f899bbabb27f1aeb66590da7159 375 SUPERFAMILY SSF56645 8 198 3.05E-27 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS04930 11559f899bbabb27f1aeb66590da7159 375 PIRSF PIRSF016578 2 371 1.7E-23 T 28-03-2018 CNX65_RS27565 aa012c2d81f501ad597258aff234d0ca 246 Pfam PF00005 ABC transporter 10 169 2.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS27565 aa012c2d81f501ad597258aff234d0ca 246 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 218 240 2.0E-12 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CNX65_RS27565 aa012c2d81f501ad597258aff234d0ca 246 Gene3D G3DSA:3.40.50.300 1 245 7.4E-58 T 28-03-2018 CNX65_RS27565 aa012c2d81f501ad597258aff234d0ca 246 SUPERFAMILY SSF52540 2 240 8.98E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27565 aa012c2d81f501ad597258aff234d0ca 246 SMART SM00382 18 217 6.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS23855 7d5bc8107c5f138edd197e7d03591e59 504 SUPERFAMILY SSF103473 7 206 1.1E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23855 7d5bc8107c5f138edd197e7d03591e59 504 SUPERFAMILY SSF103473 253 424 1.1E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23855 7d5bc8107c5f138edd197e7d03591e59 504 SUPERFAMILY SSF103473 470 497 1.1E-69 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23855 7d5bc8107c5f138edd197e7d03591e59 504 Gene3D G3DSA:1.20.1250.20 264 503 8.3E-24 T 28-03-2018 CNX65_RS23855 7d5bc8107c5f138edd197e7d03591e59 504 ProSitePatterns PS00216 Sugar transport proteins signature 1. 73 90 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS23855 7d5bc8107c5f138edd197e7d03591e59 504 Gene3D G3DSA:1.20.1250.20 1 206 1.0E-33 T 28-03-2018 CNX65_RS23855 7d5bc8107c5f138edd197e7d03591e59 504 Pfam PF07690 Major Facilitator Superfamily 23 414 2.5E-52 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS24925 e1c0ff19781e5a832d757a4431d731be 64 Gene3D G3DSA:3.90.820.10 2 64 4.0E-33 T 28-03-2018 CNX65_RS24925 e1c0ff19781e5a832d757a4431d731be 64 SMART SM00923 3 53 1.9E-31 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS24925 e1c0ff19781e5a832d757a4431d731be 64 SUPERFAMILY SSF160582 1 64 6.15E-30 T 28-03-2018 CNX65_RS24925 e1c0ff19781e5a832d757a4431d731be 64 Pfam PF03621 MbtH-like protein 1 53 1.6E-28 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS31435 6bc4106c3336fcbf56d9a02478757b91 422 Pfam PF00823 PPE family 18 162 6.8E-10 T 28-03-2018 IPR000030 PPE family CNX65_RS31435 6bc4106c3336fcbf56d9a02478757b91 422 Gene3D G3DSA:1.10.287.1060 30 114 3.5E-4 T 28-03-2018 CNX65_RS31435 6bc4106c3336fcbf56d9a02478757b91 422 SUPERFAMILY SSF140459 7 176 1.05E-17 T 28-03-2018 CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 Pfam PF00106 short chain dehydrogenase 6 193 9.4E-57 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 1.2E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 Gene3D G3DSA:3.40.50.720 1 193 3.5E-60 T 28-03-2018 CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.3E-30 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11150 b437091cc07d470f17b94011b7e5ac8b 237 SUPERFAMILY SSF51735 1 230 9.53E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS04555 f802aa8f16b70253cb8b883a89f97a4f 139 ProSitePatterns PS00354 HMG-I and HMG-Y DNA-binding domain (A+T-hook). 98 108 - T 28-03-2018 IPR000637 HMG-I/HMG-Y, DNA-binding, conserved site GO:0006355 CNX65_RS04555 f802aa8f16b70253cb8b883a89f97a4f 139 Pfam PF02467 Transcription factor WhiB 40 88 3.9E-14 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS04555 f802aa8f16b70253cb8b883a89f97a4f 139 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 102 16.074 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS31705 515bab073b7b3cb56fa2d44273d67557 140 Gene3D G3DSA:1.20.1300.10 19 131 1.0E-25 T 28-03-2018 CNX65_RS31705 515bab073b7b3cb56fa2d44273d67557 140 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 19 121 1.9E-21 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31705 515bab073b7b3cb56fa2d44273d67557 140 TIGRFAM TIGR02970 succ_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit 19 122 1.8E-27 T 28-03-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31705 515bab073b7b3cb56fa2d44273d67557 140 SUPERFAMILY SSF81343 18 124 1.22E-26 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 Gene3D G3DSA:2.40.40.20 528 677 2.9E-39 T 28-03-2018 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 SMART SM00926 1 47 6.6E-4 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 Gene3D G3DSA:3.40.50.740 50 167 2.4E-27 T 28-03-2018 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 Pfam PF00384 Molybdopterin oxidoreductase 50 476 7.4E-70 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 Gene3D G3DSA:3.40.228.10 168 245 9.6E-18 T 28-03-2018 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 SUPERFAMILY SSF53706 2 565 2.36E-157 T 28-03-2018 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 Gene3D G3DSA:2.20.25.90 1 48 2.4E-13 T 28-03-2018 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 SUPERFAMILY SSF50692 530 676 1.04E-42 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 Pfam PF01568 Molydopterin dinucleotide binding domain 565 671 4.2E-25 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CNX65_RS04120 32ed9da4094c58d6cc101d0c155a3026 677 Gene3D G3DSA:3.40.50.740 246 527 1.0E-66 T 28-03-2018 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 SUPERFAMILY SSF56655 6 258 2.23E-65 T 28-03-2018 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 84 97 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 213 227 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 Gene3D G3DSA:3.40.190.80 149 262 1.3E-25 T 28-03-2018 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 Gene3D G3DSA:3.30.540.10 2 148 6.9E-47 T 28-03-2018 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 Pfam PF00459 Inositol monophosphatase family 7 248 7.0E-58 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 84 100 1.2E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 179 200 1.2E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 42 62 1.2E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 210 234 1.2E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 64 80 1.2E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS07485 459b3e25ded23b2af82af0f12d6bc05f 266 PRINTS PR00377 Inositol monophosphatase superfamily signature 133 156 1.2E-38 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 Pfam PF13492 GAF domain 230 358 1.6E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 SUPERFAMILY SSF55874 476 564 9.82E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 Gene3D G3DSA:3.30.450.40 202 368 3.2E-18 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 Pfam PF07730 Histidine kinase 375 437 3.6E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 SMART SM00387 477 565 2.5E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 Pfam PF13185 GAF domain 55 193 1.6E-17 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 483 545 1.1E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 SUPERFAMILY SSF55781 37 218 1.9E-37 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 SMART SM00065 223 367 2.5E-4 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 SMART SM00065 55 202 4.2E-18 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 Gene3D G3DSA:3.30.565.10 441 565 2.8E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 Gene3D G3DSA:3.30.450.40 8 201 2.7E-32 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS09520 7ecae9dba2c98adbe8380822075aebf1 565 SUPERFAMILY SSF55781 206 385 4.14E-15 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 Gene3D G3DSA:3.40.50.720 1 214 5.8E-26 T 28-03-2018 CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 SUPERFAMILY SSF48179 204 332 1.13E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 PIRSF PIRSF000103 3 90 1.0E-19 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 PIRSF PIRSF000103 112 333 4.3E-44 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 129 203 2.1E-18 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 6 77 7.8E-11 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 SUPERFAMILY SSF51735 6 67 6.23E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 SUPERFAMILY SSF51735 113 208 6.23E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 206 326 3.8E-32 T 28-03-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 CNX65_RS06480 8ef023cbfb6fcf1c5f9fdc0a6cb866b7 341 Gene3D G3DSA:1.10.1040.10 215 332 1.2E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS24605 31fb1e08c64c40917de91bf40964282e 415 Pfam PF07730 Histidine kinase 189 252 2.3E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS24605 31fb1e08c64c40917de91bf40964282e 415 SUPERFAMILY SSF55874 287 405 6.36E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24605 31fb1e08c64c40917de91bf40964282e 415 Gene3D G3DSA:3.30.565.10 284 408 1.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS06420 0f6330e715206ead40444fd2e613261f 341 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 93 266 8.9E-30 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS06420 0f6330e715206ead40444fd2e613261f 341 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 94 266 3.8E-22 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS10830 98c3a1ac48bbb7efe4e42c76511b067e 320 Hamap MF_02037 Histidine N-alpha-methyltransferase [egtD]. 4 318 54.59 T 28-03-2018 IPR032888 Histidine N-alpha-methyltransferase, Actinobacteria-type GO:0008276|GO:0052699 KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CNX65_RS10830 98c3a1ac48bbb7efe4e42c76511b067e 320 Pfam PF10017 Histidine-specific methyltransferase, SAM-dependent 18 317 6.5E-105 T 28-03-2018 IPR019257 Histidine-specific methyltransferase, SAM-dependent CNX65_RS10830 98c3a1ac48bbb7efe4e42c76511b067e 320 PIRSF PIRSF018005 2 319 5.5E-121 T 28-03-2018 IPR017804 Methyltransferase EgtD-like CNX65_RS10830 98c3a1ac48bbb7efe4e42c76511b067e 320 SUPERFAMILY SSF53335 37 203 2.11E-10 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS10830 98c3a1ac48bbb7efe4e42c76511b067e 320 SUPERFAMILY SSF53335 253 313 2.11E-10 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS10830 98c3a1ac48bbb7efe4e42c76511b067e 320 TIGRFAM TIGR03438 egtD_ergothio: dimethylhistidine N-methyltransferase 17 315 1.5E-104 T 28-03-2018 IPR035094 Histidine N-alpha-methyltransferase KEGG: 00340+2.1.1.44|MetaCyc: PWY-7255|MetaCyc: PWY-7550 CNX65_RS10830 98c3a1ac48bbb7efe4e42c76511b067e 320 Gene3D G3DSA:3.40.50.150 9 318 7.8E-20 T 28-03-2018 CNX65_RS29985 dc9cbfb044993037c929174f6ab64c4a 323 Gene3D G3DSA:1.25.40.120 5 314 2.0E-5 T 28-03-2018 CNX65_RS25510 d503c5672437a22141585fa502869a88 69 Gene3D G3DSA:1.10.10.10 4 68 6.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 2 585 32.119 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 Gene3D G3DSA:3.30.930.10 132 587 4.3E-107 T 28-03-2018 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 Pfam PF01336 OB-fold nucleic acid binding domain 19 101 6.8E-15 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 475 491 2.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 519 533 2.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 208 221 2.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 191 203 2.4E-26 T 28-03-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 SUPERFAMILY SSF55681 417 583 1.14E-99 T 28-03-2018 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 SUPERFAMILY SSF55681 115 293 1.14E-99 T 28-03-2018 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 Pfam PF02938 GAD domain 313 394 1.7E-14 T 28-03-2018 IPR029351 GAD domain Reactome: R-HSA-379726 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 Gene3D G3DSA:2.40.50.140 1 107 7.6E-25 T 28-03-2018 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 119 558 5.1E-102 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 SUPERFAMILY SSF50249 2 104 1.14E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 SUPERFAMILY SSF55261 290 412 4.14E-35 T 28-03-2018 IPR004115 GAD-like domain GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 CNX65_RS08575 528b03ca9520a9e754a6de56df1c07ee 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 581 2.5E-208 T 28-03-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 18 719 7.2E-267 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SUPERFAMILY SSF54791 582 668 2.82E-17 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SUPERFAMILY SSF54211 10 152 2.02E-46 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Gene3D G3DSA:3.30.300.20 557 622 1.1E-13 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Gene3D G3DSA:3.30.230.70 341 556 3.2E-49 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 PIRSF PIRSF005499 8 747 9.8E-287 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Gene3D G3DSA:1.10.10.400 278 340 5.4E-25 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SUPERFAMILY SSF50249 647 717 1.72E-14 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Pfam PF00013 KH domain 583 639 5.9E-10 T 28-03-2018 IPR004088 K Homology domain, type 1 GO:0003723 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 269 343 7.5E-20 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Pfam PF00575 S1 RNA binding domain 648 717 2.6E-13 T 28-03-2018 IPR003029 S1 domain GO:0003676 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SUPERFAMILY SSF46915 266 345 4.71E-19 T 28-03-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0000175|GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Gene3D G3DSA:3.30.230.70 18 277 1.2E-49 T 28-03-2018 IPR027408 PNPase/RNase PH domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SMART SM00316 649 720 3.5E-17 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 TIGRFAM TIGR02696 pppGpp_PNP: guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase 5 718 0.0 T 28-03-2018 IPR014069 Guanosine pentaphosphate synthetase I/polyribonucleotide nucleotidyltransferase GO:0004654|GO:0005737|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Gene3D G3DSA:2.40.50.140 651 747 1.6E-17 T 28-03-2018 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 10 723 27.097 T 28-03-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Pfam PF01138 3' exoribonuclease family, domain 1 21 152 1.1E-17 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 Pfam PF01138 3' exoribonuclease family, domain 1 348 480 5.7E-14 T 28-03-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SUPERFAMILY SSF55666 474 573 5.07E-23 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SUPERFAMILY SSF54211 319 515 2.08E-42 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SMART SM00322 579 644 1.3E-10 T 28-03-2018 IPR004087 K Homology domain GO:0003676 CNX65_RS28560 6ec8cbd20f97aaaedf01bfd28e969e0d 747 SUPERFAMILY SSF55666 153 259 5.07E-27 T 28-03-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00473 Galactokinase signature 29 47 5.7E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00473 Galactokinase signature 115 133 5.7E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00473 Galactokinase signature 96 107 5.7E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00473 Galactokinase signature 276 290 5.7E-25 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 ProSitePatterns PS00106 Galactokinase signature. 29 40 - T 28-03-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 SUPERFAMILY SSF54211 7 212 2.2E-51 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 SUPERFAMILY SSF55060 218 391 1.8E-47 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 Pfam PF10509 Galactokinase galactose-binding signature 12 60 4.8E-21 T 28-03-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PIRSF PIRSF000530 2 394 7.7E-113 T 28-03-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0008152|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 Gene3D G3DSA:3.30.70.890 220 392 1.2E-53 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 TIGRFAM TIGR00131 gal_kin: galactokinase 11 369 3.8E-82 T 28-03-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 Gene3D G3DSA:3.30.230.10 5 219 1.0E-53 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 Pfam PF00288 GHMP kinases N terminal domain 117 190 2.8E-11 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00959 Mevalonate kinase family signature 122 144 3.0E-39 T 28-03-2018 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00959 Mevalonate kinase family signature 339 356 3.0E-39 T 28-03-2018 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00959 Mevalonate kinase family signature 172 191 3.0E-39 T 28-03-2018 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 PRINTS PR00959 Mevalonate kinase family signature 27 51 3.0E-39 T 28-03-2018 CNX65_RS07260 fac034e6ed326c47e988e30f6a495fd8 394 Pfam PF08544 GHMP kinases C terminal 293 371 1.8E-10 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS06415 263a81104bbc7dcebb0fe63f8028eea3 260 Gene3D G3DSA:3.40.50.720 1 136 2.3E-13 T 28-03-2018 CNX65_RS06415 263a81104bbc7dcebb0fe63f8028eea3 260 SUPERFAMILY SSF51735 1 112 3.22E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06415 263a81104bbc7dcebb0fe63f8028eea3 260 PIRSF PIRSF000103 1 260 2.2E-21 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CNX65_RS06415 263a81104bbc7dcebb0fe63f8028eea3 260 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 1 96 2.3E-4 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS06415 263a81104bbc7dcebb0fe63f8028eea3 260 Gene3D G3DSA:1.10.1040.10 137 260 1.2E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 Gene3D G3DSA:3.30.1490.20 36 87 8.8E-24 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 Pfam PF08442 ATP-grasp domain 2 194 3.8E-69 T 28-03-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 Gene3D G3DSA:3.40.50.261 3 35 0.17 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 SUPERFAMILY SSF56059 3 228 8.75E-68 T 28-03-2018 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 SUPERFAMILY SSF52210 231 385 1.96E-41 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 PIRSF PIRSF001554 1 388 7.3E-139 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 Gene3D G3DSA:3.40.50.261 232 385 2.5E-37 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 385 1.7E-127 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 38.336 T 28-03-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 Gene3D G3DSA:3.30.470.20 88 231 1.9E-50 T 28-03-2018 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 273 - T 28-03-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS31935 37baabb8e9d6a0ea9fa3b9c0e3a45426 389 Pfam PF00549 CoA-ligase 256 378 1.0E-13 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 Pfam PF00089 Trypsin 38 254 4.2E-56 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 Gene3D G3DSA:2.40.10.10 133 261 5.0E-37 T 28-03-2018 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 SUPERFAMILY SSF50494 1 254 9.56E-66 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 Gene3D G3DSA:2.40.10.10 70 132 1.8E-19 T 28-03-2018 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 75 80 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 210 222 4.6E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 121 135 4.6E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 65 80 4.6E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 211 222 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 Gene3D G3DSA:2.40.10.10 38 69 6.2E-14 T 28-03-2018 CNX65_RS28725 a84c38534cca53a6b23804cd21dcd6bd 261 SMART SM00020 37 256 2.8E-68 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS00240 1e32008b6a6549993e9d2605a3b1b8e6 615 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 66 517 1.6E-160 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CNX65_RS00240 1e32008b6a6549993e9d2605a3b1b8e6 615 ProSitePatterns PS01303 BCCT family of transporters signature. 335 344 - T 28-03-2018 IPR018093 BCCT transporter, conserved site GO:0005215|GO:0006810|GO:0016020 CNX65_RS00240 1e32008b6a6549993e9d2605a3b1b8e6 615 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 28 516 6.2E-176 T 28-03-2018 IPR000060 BCCT transporter family GO:0005215|GO:0006810|GO:0016020 CNX65_RS00240 1e32008b6a6549993e9d2605a3b1b8e6 615 Gene3D G3DSA:1.10.357.10 118 268 0.019 T 28-03-2018 CNX65_RS31215 ec0ba9521a93fb8c83c007338b8137aa 822 SUPERFAMILY SSF53756 373 759 3.2E-27 T 28-03-2018 CNX65_RS31215 ec0ba9521a93fb8c83c007338b8137aa 822 Gene3D G3DSA:3.90.550.10 1 254 3.0E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31215 ec0ba9521a93fb8c83c007338b8137aa 822 Gene3D G3DSA:3.40.50.2000 555 747 1.4E-28 T 28-03-2018 CNX65_RS31215 ec0ba9521a93fb8c83c007338b8137aa 822 SUPERFAMILY SSF53448 1 244 1.46E-52 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31215 ec0ba9521a93fb8c83c007338b8137aa 822 Pfam PF13692 Glycosyl transferases group 1 571 726 3.8E-11 T 28-03-2018 CNX65_RS31215 ec0ba9521a93fb8c83c007338b8137aa 822 Pfam PF00535 Glycosyl transferase family 2 2 174 1.2E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS18055 dcabed44b7831e5189610c5c37b47c09 191 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 4.9E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18055 dcabed44b7831e5189610c5c37b47c09 191 SUPERFAMILY SSF46689 3 79 3.33E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS18055 dcabed44b7831e5189610c5c37b47c09 191 SUPERFAMILY SSF48498 77 184 3.26E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS18055 dcabed44b7831e5189610c5c37b47c09 191 Gene3D G3DSA:1.10.357.10 9 191 2.4E-34 T 28-03-2018 CNX65_RS18055 dcabed44b7831e5189610c5c37b47c09 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18055 dcabed44b7831e5189610c5c37b47c09 191 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.1E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS05860 4cc47bbcfb0c4631564bb245e6e01c15 655 Pfam PF04055 Radical SAM superfamily 268 432 4.9E-18 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS05860 4cc47bbcfb0c4631564bb245e6e01c15 655 SUPERFAMILY SSF102114 231 635 3.79E-50 T 28-03-2018 CNX65_RS05860 4cc47bbcfb0c4631564bb245e6e01c15 655 Gene3D G3DSA:3.20.20.70 167 574 4.3E-40 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS05860 4cc47bbcfb0c4631564bb245e6e01c15 655 TIGRFAM TIGR03960 rSAM_fuse_unch: radical SAM family uncharacterized protein 13 620 2.1E-210 T 28-03-2018 IPR023862 Conserved hypothetical protein CHP03960, radical SAM CNX65_RS05860 4cc47bbcfb0c4631564bb245e6e01c15 655 SMART SM00729 264 487 3.2E-28 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 Pfam PF00027 Cyclic nucleotide-binding domain 23 108 1.1E-18 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 SUPERFAMILY SSF46785 138 211 1.89E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 SMART SM00100 4 121 5.0E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 Pfam PF13545 Crp-like helix-turn-helix domain 140 208 8.9E-18 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 Gene3D G3DSA:1.10.10.10 136 211 7.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 Gene3D G3DSA:2.60.120.10 3 135 2.9E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 SUPERFAMILY SSF51206 5 130 7.46E-22 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS28340 3d32c2a5ee10f164707edad37309233a 212 SMART SM00419 155 203 2.2E-7 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 SUPERFAMILY SSF52540 307 507 5.51E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 Gene3D G3DSA:3.40.50.300 2 287 1.9E-53 T 28-03-2018 CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 Pfam PF00005 ABC transporter 21 188 7.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 Pfam PF00005 ABC transporter 338 471 1.0E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 SUPERFAMILY SSF52540 8 241 3.38E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 ProSitePatterns PS00211 ABC transporters family signature. 443 457 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 SMART SM00382 346 516 2.0E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 SMART SM00382 30 242 1.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 Pfam PF12848 ABC transporter 227 303 1.5E-14 T 28-03-2018 IPR032781 ABC-transporter extension domain CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 TIGRFAM TIGR03719 ABC_ABC_ChvD: ATP-binding cassette protein, ChvD family 3 555 3.4E-268 T 28-03-2018 IPR022374 ABC transporter, ATP-binding protein, ChvD CNX65_RS05610 b35f5727883ccbe0ffcb5c523e305de8 558 Gene3D G3DSA:3.40.50.300 288 544 1.8E-48 T 28-03-2018 CNX65_RS02105 5782f05d8d24a3e22dcbd9c4d9ccfae9 258 Hamap MF_00443 Thiazole synthase [thiG]. 9 257 41.255 T 28-03-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CNX65_RS02105 5782f05d8d24a3e22dcbd9c4d9ccfae9 258 SUPERFAMILY SSF110399 8 246 4.97E-84 T 28-03-2018 CNX65_RS02105 5782f05d8d24a3e22dcbd9c4d9ccfae9 258 Pfam PF05690 Thiazole biosynthesis protein ThiG 12 254 8.9E-106 T 28-03-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 CNX65_RS02105 5782f05d8d24a3e22dcbd9c4d9ccfae9 258 Gene3D G3DSA:3.20.20.70 7 258 1.3E-54 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS09825 1f49d51922874d8a0513f9832e74a47e 480 Pfam PF05977 Transmembrane secretion effector 85 466 6.0E-23 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS09825 1f49d51922874d8a0513f9832e74a47e 480 SUPERFAMILY SSF103473 85 471 3.01E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS09825 1f49d51922874d8a0513f9832e74a47e 480 Gene3D G3DSA:1.20.1250.20 83 265 1.3E-9 T 28-03-2018 CNX65_RS09825 1f49d51922874d8a0513f9832e74a47e 480 Gene3D G3DSA:1.20.1250.20 283 472 2.2E-25 T 28-03-2018 CNX65_RS04525 cdf9132a5aaf2552c918f3cf81984969 236 Gene3D G3DSA:3.40.50.1000 81 235 7.6E-19 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS04525 cdf9132a5aaf2552c918f3cf81984969 236 SUPERFAMILY SSF56784 17 39 1.12E-22 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS04525 cdf9132a5aaf2552c918f3cf81984969 236 SUPERFAMILY SSF56784 98 234 1.12E-22 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS04525 cdf9132a5aaf2552c918f3cf81984969 236 Pfam PF13419 Haloacid dehalogenase-like hydrolase 98 204 1.3E-9 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33455 6022693aa8972c84285cc856bad588e8 432 Gene3D G3DSA:1.10.10.10 355 431 6.3E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33455 6022693aa8972c84285cc856bad588e8 432 SUPERFAMILY SSF88946 4 94 3.73E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS33455 6022693aa8972c84285cc856bad588e8 432 Gene3D G3DSA:1.10.1740.10 1 110 2.6E-16 T 28-03-2018 CNX65_RS33455 6022693aa8972c84285cc856bad588e8 432 Pfam PF04542 Sigma-70 region 2 25 89 3.9E-8 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 SUPERFAMILY SSF53901 273 392 7.41E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 PIRSF PIRSF000429 1 394 2.7E-115 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 ProSitePatterns PS00099 Thiolases active site. 376 389 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 Pfam PF02803 Thiolase, C-terminal domain 272 393 6.8E-35 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 Gene3D G3DSA:3.40.47.10 158 258 3.8E-19 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 392 6.1E-124 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 Gene3D G3DSA:3.40.47.10 1 151 8.9E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 Pfam PF00108 Thiolase, N-terminal domain 6 264 2.1E-66 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 SUPERFAMILY SSF53901 1 267 1.2E-70 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS00840 d3224b57c77b6e34c218b01c20aabf65 394 Gene3D G3DSA:3.40.47.10 259 394 6.9E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 SUPERFAMILY SSF81296 1 71 7.4E-13 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 SUPERFAMILY SSF51445 69 493 1.34E-105 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 Gene3D G3DSA:2.60.40.10 1 63 7.0E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 TIGRFAM TIGR02402 trehalose_TreZ: malto-oligosyltrehalose trehalohydrolase 2 524 4.4E-217 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 Gene3D G3DSA:3.20.20.80 64 494 3.0E-82 T 28-03-2018 CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 PIRSF PIRSF006337 1 528 6.4E-217 T 28-03-2018 IPR012768 Malto-oligosyltrehalose trehalohydrolase GO:0004553|GO:0005992 KEGG: 00500+3.2.1.141|KEGG: 00520+3.2.1.14|MetaCyc: PWY-2661|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 SMART SM00642 93 441 7.8E-9 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 Pfam PF11941 Domain of unknown function (DUF3459) 479 551 1.6E-9 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CNX65_RS25405 77fdbf4b3dd924fb1bdcba451e46cd7a 630 Pfam PF00128 Alpha amylase, catalytic domain 107 188 7.3E-12 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS03410 22c72c03e7f007cd42146cb45ecb742b 317 PIRSF PIRSF002849 1 314 1.0E-122 T 28-03-2018 CNX65_RS03410 22c72c03e7f007cd42146cb45ecb742b 317 SUPERFAMILY SSF52540 23 285 3.25E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03410 22c72c03e7f007cd42146cb45ecb742b 317 Gene3D G3DSA:1.10.8.300 201 309 4.5E-30 T 28-03-2018 CNX65_RS03410 22c72c03e7f007cd42146cb45ecb742b 317 Gene3D G3DSA:3.40.50.300 20 186 2.2E-24 T 28-03-2018 CNX65_RS03410 22c72c03e7f007cd42146cb45ecb742b 317 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 39 169 2.8E-62 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CNX65_RS24225 e700805911bb11e08279d4baf17ffa60 349 Pfam PF01032 FecCD transport family 35 343 5.9E-75 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS24225 e700805911bb11e08279d4baf17ffa60 349 SUPERFAMILY SSF81345 15 343 1.44E-59 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS24225 e700805911bb11e08279d4baf17ffa60 349 Gene3D G3DSA:1.10.3470.10 16 348 8.2E-57 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS08330 93d2b4b4a4d653afcd6e2e72ad1960aa 248 Pfam PF00005 ABC transporter 20 172 6.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS08330 93d2b4b4a4d653afcd6e2e72ad1960aa 248 SMART SM00382 29 219 5.2E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08330 93d2b4b4a4d653afcd6e2e72ad1960aa 248 Gene3D G3DSA:3.40.50.300 2 246 4.4E-58 T 28-03-2018 CNX65_RS08330 93d2b4b4a4d653afcd6e2e72ad1960aa 248 TIGRFAM TIGR03411 urea_trans_UrtD: urea ABC transporter, ATP-binding protein UrtD 4 242 6.8E-99 T 28-03-2018 IPR017781 ABC transporter, urea, ATP-binding protein, UrtD CNX65_RS08330 93d2b4b4a4d653afcd6e2e72ad1960aa 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 223 241 6.2E-6 T 28-03-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal CNX65_RS08330 93d2b4b4a4d653afcd6e2e72ad1960aa 248 SUPERFAMILY SSF52540 4 241 2.02E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 Pfam PF03561 Allantoicase repeat 18 163 2.0E-42 T 28-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 Pfam PF03561 Allantoicase repeat 185 312 2.0E-34 T 28-03-2018 IPR015908 Allantoicase domain GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 PIRSF PIRSF016516 2 266 8.6E-84 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 PIRSF PIRSF016516 259 330 7.9E-12 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 SUPERFAMILY SSF49785 175 314 5.53E-41 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 Hamap MF_00813 Probable allantoicase [alc]. 1 315 43.084 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 TIGRFAM TIGR02961 allantoicase: allantoicase 9 312 1.4E-115 T 28-03-2018 IPR005164 Allantoicase GO:0000256|GO:0004037 KEGG: 00230+3.5.3.4|MetaCyc: PWY-5697 CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 SUPERFAMILY SSF49785 6 167 2.72E-49 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 Gene3D G3DSA:2.60.120.260 173 317 2.6E-46 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS29140 766eddbd0158cafc8409329a8c31ea06 331 Gene3D G3DSA:2.60.120.260 1 168 5.1E-61 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 81 1.6E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 41 55 2.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 55 71 2.6E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 SUPERFAMILY SSF46785 11 85 2.21E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 SMART SM00345 22 81 7.4E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 Gene3D G3DSA:1.10.10.10 6 83 3.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 Gene3D G3DSA:3.90.1150.10 362 455 2.2E-11 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 SUPERFAMILY SSF53383 76 452 5.02E-67 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 Gene3D G3DSA:3.40.640.10 118 361 4.7E-33 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS29435 b45fbd65edbcec8c6dce88518ada10ad 456 Pfam PF00155 Aminotransferase class I and II 136 400 9.5E-11 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS30395 e9c7e30cd4f896bb854d1cfa588fce49 197 SUPERFAMILY SSF55961 46 190 6.52E-40 T 28-03-2018 CNX65_RS30395 e9c7e30cd4f896bb854d1cfa588fce49 197 Gene3D G3DSA:3.30.530.20 34 191 1.4E-25 T 28-03-2018 IPR023393 START-like domain CNX65_RS30395 e9c7e30cd4f896bb854d1cfa588fce49 197 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 59 190 9.9E-26 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 SMART SM00382 381 538 2.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 SMART SM00382 48 249 2.9E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 Gene3D G3DSA:3.40.50.300 359 535 1.5E-33 T 28-03-2018 CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 Pfam PF00005 ABC transporter 375 497 2.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 Pfam PF00005 ABC transporter 39 204 4.3E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 SUPERFAMILY SSF52540 375 534 1.39E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 Gene3D G3DSA:3.40.50.300 20 301 1.4E-36 T 28-03-2018 CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 SUPERFAMILY SSF52540 145 248 9.35E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13270 0cf757ff549295a22f063468fff0ce5c 540 SUPERFAMILY SSF52540 21 114 9.35E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 44 284 1.3E-89 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 126 142 7.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 227 239 7.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 104 117 7.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 7.6E-21 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 Gene3D G3DSA:3.90.230.10 40 285 5.3E-85 T 28-03-2018 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 Pfam PF00557 Metallopeptidase family M24 48 276 3.3E-51 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 202 220 - T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 SUPERFAMILY SSF55920 5 284 2.09E-87 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS28875 8e4787ff10c9d05de4d11d2cd691a41f 285 Hamap MF_01974 Methionine aminopeptidase [map]. 39 285 39.359 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS12360 dc054edf614491e64a7e79dcef389605 350 Gene3D G3DSA:3.20.20.70 74 350 1.8E-56 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS12360 dc054edf614491e64a7e79dcef389605 350 Pfam PF03537 Glycoside-hydrolase family GH114 96 342 1.1E-76 T 28-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CNX65_RS12360 dc054edf614491e64a7e79dcef389605 350 SUPERFAMILY SSF51445 133 344 7.58E-36 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS23430 a92607e0b9a7c730d8638f9c400d87ca 133 SUPERFAMILY SSF54427 11 128 1.02E-23 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS23430 a92607e0b9a7c730d8638f9c400d87ca 133 Pfam PF12680 SnoaL-like domain 18 120 2.6E-9 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS23430 a92607e0b9a7c730d8638f9c400d87ca 133 Gene3D G3DSA:3.10.450.50 2 124 5.0E-15 T 28-03-2018 CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 Gene3D G3DSA:3.40.50.150 5 116 7.1E-8 T 28-03-2018 CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 Pfam PF01795 MraW methylase family 5 311 7.4E-110 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 4 311 8.3E-89 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 7 312 36.408 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 PIRSF PIRSF004486 1 313 4.6E-93 T 28-03-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 SUPERFAMILY SSF53335 7 115 1.01E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 SUPERFAMILY SSF53335 217 312 1.01E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 Gene3D G3DSA:1.10.150.170 117 219 3.9E-37 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28290 952621c1fe09a6c5a8e1b3a386c2f6a8 316 SUPERFAMILY SSF81799 116 217 4.45E-32 T 28-03-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 Gene3D G3DSA:2.60.120.280 38 182 1.7E-10 T 28-03-2018 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 251 293 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 SUPERFAMILY SSF46689 197 248 9.73E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 Pfam PF12833 Helix-turn-helix domain 220 297 6.3E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 SMART SM00342 214 297 2.6E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 SUPERFAMILY SSF46689 250 299 6.45E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 Gene3D G3DSA:1.10.10.60 253 309 3.0E-12 T 28-03-2018 CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 Pfam PF12852 Cupin 5 181 1.4E-25 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CNX65_RS22150 a3750dfcaa5bad7607cc4711a5f23746 337 Gene3D G3DSA:1.10.10.60 194 252 1.3E-8 T 28-03-2018 CNX65_RS31035 1f90e4109c1293df3af4a251b607ea7d 462 TIGRFAM TIGR02946 acyl_WS_DGAT: acyltransferase, WS/DGAT/MGAT 5 457 2.3E-145 T 28-03-2018 IPR014292 Acyltransferase, WS/DGAT/MGAT GO:0016746|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CNX65_RS31035 1f90e4109c1293df3af4a251b607ea7d 462 Pfam PF06974 Protein of unknown function (DUF1298) 314 456 1.9E-28 T 28-03-2018 IPR009721 O-acyltransferase WSD1, C-terminal GO:0004144 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CNX65_RS31035 1f90e4109c1293df3af4a251b607ea7d 462 Pfam PF03007 Wax ester synthase-like Acyl-CoA acyltransferase domain 5 269 3.4E-75 T 28-03-2018 IPR004255 O-acyltransferase, WSD1, N-terminal GO:0004144|GO:0045017 KEGG: 00073+2.3.1.20|KEGG: 00561+2.3.1.20 CNX65_RS31035 1f90e4109c1293df3af4a251b607ea7d 462 SUPERFAMILY SSF52777 5 155 3.34E-8 T 28-03-2018 CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 SUPERFAMILY SSF55781 288 432 2.84E-13 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 Gene3D G3DSA:3.20.20.450 599 860 1.6E-95 T 28-03-2018 IPR001633 EAL domain CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 431 582 5.0E-14 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 SMART SM00052 601 846 5.6E-105 T 28-03-2018 IPR001633 EAL domain CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 Pfam PF00990 Diguanylate cyclase, GGDEF domain 434 584 6.4E-19 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 SMART SM00065 283 431 1.5E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 SUPERFAMILY SSF55073 439 582 1.57E-21 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 SUPERFAMILY SSF141868 608 854 3.92E-84 T 28-03-2018 IPR001633 EAL domain CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 Pfam PF00563 EAL domain 608 841 1.1E-69 T 28-03-2018 IPR001633 EAL domain CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 Gene3D G3DSA:3.30.450.40 235 421 1.6E-20 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 Pfam PF13492 GAF domain 288 423 3.7E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 SMART SM00267 423 592 2.4E-19 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS32640 e86cb1da9da3c6d34bffa9dd1ee102cf 871 Gene3D G3DSA:3.30.70.270 422 598 4.4E-32 T 28-03-2018 CNX65_RS14530 1a3c5e48a1d73761e9d1e76c93ab780d 236 Pfam PF00027 Cyclic nucleotide-binding domain 28 111 3.8E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS14530 1a3c5e48a1d73761e9d1e76c93ab780d 236 SUPERFAMILY SSF46785 146 220 1.14E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14530 1a3c5e48a1d73761e9d1e76c93ab780d 236 Gene3D G3DSA:2.60.120.10 5 147 1.7E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS14530 1a3c5e48a1d73761e9d1e76c93ab780d 236 SUPERFAMILY SSF51206 9 132 1.83E-21 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS14530 1a3c5e48a1d73761e9d1e76c93ab780d 236 SMART SM00100 9 124 6.6E-8 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS14530 1a3c5e48a1d73761e9d1e76c93ab780d 236 Gene3D G3DSA:1.10.10.10 148 226 4.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14530 1a3c5e48a1d73761e9d1e76c93ab780d 236 Pfam PF13545 Crp-like helix-turn-helix domain 147 218 2.7E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS24715 f36d29c016d8190979bde1d5e697c8db 405 SUPERFAMILY SSF56112 53 212 6.33E-10 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS24715 f36d29c016d8190979bde1d5e697c8db 405 Gene3D G3DSA:3.40.80.10 212 272 4.8E-4 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24715 f36d29c016d8190979bde1d5e697c8db 405 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 237 338 1.8E-12 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24715 f36d29c016d8190979bde1d5e697c8db 405 SMART SM00644 229 338 5.6E-5 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24715 f36d29c016d8190979bde1d5e697c8db 405 SUPERFAMILY SSF55846 223 340 1.83E-17 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24715 f36d29c016d8190979bde1d5e697c8db 405 Gene3D G3DSA:3.40.80.10 273 353 1.5E-13 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS26400 4b673cf3bac121e66d07ef15a206673d 463 Pfam PF00106 short chain dehydrogenase 141 228 6.0E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26400 4b673cf3bac121e66d07ef15a206673d 463 SUPERFAMILY SSF51735 309 415 5.4E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26400 4b673cf3bac121e66d07ef15a206673d 463 SUPERFAMILY SSF51735 135 233 5.4E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26400 4b673cf3bac121e66d07ef15a206673d 463 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 157 1.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26400 4b673cf3bac121e66d07ef15a206673d 463 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 216 227 1.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26400 4b673cf3bac121e66d07ef15a206673d 463 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 374 393 1.1E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26400 4b673cf3bac121e66d07ef15a206673d 463 Gene3D G3DSA:3.40.50.720 80 451 6.1E-53 T 28-03-2018 CNX65_RS16410 a9f32d362b33013738235a0c15343d6d 432 SUPERFAMILY SSF55874 323 428 1.14E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16410 a9f32d362b33013738235a0c15343d6d 432 Pfam PF07730 Histidine kinase 236 301 4.9E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS16410 a9f32d362b33013738235a0c15343d6d 432 Gene3D G3DSA:3.30.565.10 301 432 1.6E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 SUPERFAMILY SSF51735 248 410 2.68E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 SMART SM00996 16 489 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 SMART SM00997 248 410 5.6E-107 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 88 102 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 16 489 6.9E-145 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 SUPERFAMILY SSF52283 200 247 3.0E-111 T 28-03-2018 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 SUPERFAMILY SSF52283 411 490 3.0E-111 T 28-03-2018 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 SUPERFAMILY SSF52283 15 162 3.0E-111 T 28-03-2018 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 Gene3D G3DSA:3.40.50.1480 262 463 2.1E-81 T 28-03-2018 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 17 482 1.7E-191 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 Gene3D G3DSA:3.40.50.1480 5 261 5.3E-109 T 28-03-2018 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 12 482 48.337 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 270 286 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 PIRSF PIRSF001109 6 490 6.7E-190 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS31100 fa7f4f4869cea1bc0e2b1846406e80cb 490 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 248 410 1.3E-79 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS13845 1701599bdaf95acf42b79ceac4ae6f98 505 Pfam PF00561 alpha/beta hydrolase fold 79 268 4.6E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS13845 1701599bdaf95acf42b79ceac4ae6f98 505 Pfam PF08386 TAP-like protein 377 477 2.8E-19 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS13845 1701599bdaf95acf42b79ceac4ae6f98 505 SUPERFAMILY SSF53474 402 449 1.18E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13845 1701599bdaf95acf42b79ceac4ae6f98 505 SUPERFAMILY SSF53474 68 124 1.18E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13845 1701599bdaf95acf42b79ceac4ae6f98 505 SUPERFAMILY SSF53474 311 359 1.18E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13845 1701599bdaf95acf42b79ceac4ae6f98 505 SUPERFAMILY SSF53474 166 225 1.18E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13845 1701599bdaf95acf42b79ceac4ae6f98 505 Gene3D G3DSA:3.40.50.1820 57 477 3.5E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS08825 685e3d6e193049942f85de38674928a2 401 Pfam PF02371 Transposase IS116/IS110/IS902 family 272 355 1.3E-25 T 28-03-2018 IPR003346 Transposase, IS116/IS110/IS902 GO:0003677|GO:0004803|GO:0006313 CNX65_RS08825 685e3d6e193049942f85de38674928a2 401 Pfam PF01548 Transposase 9 163 1.8E-42 T 28-03-2018 IPR002525 Transposase, IS111A/IS1328/IS1533, N-terminal GO:0003677|GO:0004803|GO:0006313 CNX65_RS08825 685e3d6e193049942f85de38674928a2 401 Gene3D G3DSA:1.10.8.50 263 360 2.8E-4 T 28-03-2018 CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 SUPERFAMILY SSF103473 13 397 4.84E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 Pfam PF07690 Major Facilitator Superfamily 19 349 7.9E-21 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 Gene3D G3DSA:1.20.1250.20 209 404 4.1E-11 T 28-03-2018 CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 143 164 2.6E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 18 40 2.6E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 297 320 2.6E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 PRINTS PR01988 Putative bacilysin exporter bacE signature 170 187 2.6E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS01825 b1e1ccb274cb55885109f5b5c06ce34e 407 Gene3D G3DSA:1.20.1250.20 5 208 2.4E-17 T 28-03-2018 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 PIRSF PIRSF002134 1 125 9.0E-43 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 SUPERFAMILY SSF46946 2 122 1.05E-45 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 120 27.616 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 ProSitePatterns PS00646 Ribosomal protein S13 signature. 88 101 - T 28-03-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 115 1.7E-52 T 28-03-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 Pfam PF00416 Ribosomal protein S13/S18 3 109 1.1E-31 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 Gene3D G3DSA:4.10.910.10 68 86 5.0E-15 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 Gene3D G3DSA:1.10.8.50 1 67 2.6E-23 T 28-03-2018 CNX65_RS32315 990df259c7644868aa6dd8b4a1f5876d 126 Gene3D G3DSA:4.10.910.10 87 122 4.7E-26 T 28-03-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS20950 24ef9b24894944c802f21830ef253bc0 519 Pfam PF00795 Carbon-nitrogen hydrolase 263 469 1.3E-19 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS20950 24ef9b24894944c802f21830ef253bc0 519 Hamap MF_01148 Apolipoprotein N-acyltransferase [lnt]. 20 486 15.708 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CNX65_RS20950 24ef9b24894944c802f21830ef253bc0 519 SUPERFAMILY SSF56317 220 478 3.66E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS20950 24ef9b24894944c802f21830ef253bc0 519 TIGRFAM TIGR00546 lnt: apolipoprotein N-acyltransferase 72 448 1.4E-74 T 28-03-2018 IPR004563 Apolipoprotein N-acyltransferase GO:0016021|GO:0016410|GO:0042158 CNX65_RS20950 24ef9b24894944c802f21830ef253bc0 519 Gene3D G3DSA:3.60.110.10 207 480 2.0E-38 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS19520 01dece2fb782727229a02bf1a2860a8f 484 Pfam PF00743 Flavin-binding monooxygenase-like 14 191 3.5E-16 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS19520 01dece2fb782727229a02bf1a2860a8f 484 Gene3D G3DSA:3.50.50.60 1 143 4.2E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19520 01dece2fb782727229a02bf1a2860a8f 484 SUPERFAMILY SSF51905 2 208 3.09E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19520 01dece2fb782727229a02bf1a2860a8f 484 SUPERFAMILY SSF51905 274 389 3.09E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19520 01dece2fb782727229a02bf1a2860a8f 484 Gene3D G3DSA:3.50.50.60 144 467 4.7E-60 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 PRINTS PR00723 Subtilisin serine protease family (S8) signature 242 255 7.6E-22 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 PRINTS PR00723 Subtilisin serine protease family (S8) signature 411 427 7.6E-22 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 PRINTS PR00723 Subtilisin serine protease family (S8) signature 205 224 7.6E-22 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 412 422 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 Gene3D G3DSA:3.40.50.200 166 475 1.6E-92 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 Pfam PF00082 Subtilase family 205 461 5.5E-63 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 210 221 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 Gene3D G3DSA:2.60.40.10 476 577 0.0024 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS18050 a97362bdd2687c922841af6875c634ce 1066 SUPERFAMILY SSF52743 187 470 3.27E-85 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 Pfam PF00005 ABC transporter 515 722 3.0E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 SUPERFAMILY SSF52540 507 775 1.01E-37 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 Gene3D G3DSA:1.20.1580.10 123 371 1.1E-58 T 28-03-2018 CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 Gene3D G3DSA:3.40.50.300 5 122 0.095 T 28-03-2018 CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 Gene3D G3DSA:3.40.50.300 372 491 1.1E-18 T 28-03-2018 CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 SMART SM00382 50 461 2.2 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 SMART SM00382 524 768 0.4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 Gene3D G3DSA:3.40.50.300 492 801 7.8E-54 T 28-03-2018 CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 SUPERFAMILY SSF52540 261 467 1.15E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18660 d675d8c4d76cbaacf7817743d665746d 803 SUPERFAMILY SSF52540 31 79 1.15E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 Pfam PF00589 Phage integrase family 117 281 3.8E-48 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 11 92 9.2E-21 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 Gene3D G3DSA:1.10.150.130 6 113 8.3E-25 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 SUPERFAMILY SSF56349 5 289 5.59E-60 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 8 297 56.163 T 28-03-2018 IPR023009 Tyrosine recombinase XerC/XerD CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 12 297 7.7E-104 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 6 297 55.65 T 28-03-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 CNX65_RS27040 15f6de8591b3904ce0650e0553da4e58 299 Gene3D G3DSA:1.10.443.10 114 291 2.0E-50 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 16 341 40.247 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 Gene3D G3DSA:3.20.20.70 12 341 8.2E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 16 341 7.6E-109 T 28-03-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 Reactome: R-HSA-947581 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 31 42 - T 28-03-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 Reactome: R-HSA-947581 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 Pfam PF04055 Radical SAM superfamily 30 191 2.2E-30 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 Pfam PF06463 Molybdenum Cofactor Synthesis C 197 323 4.8E-36 T 28-03-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 Reactome: R-HSA-947581 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 SUPERFAMILY SSF102114 16 289 1.31E-70 T 28-03-2018 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 Pfam PF13353 4Fe-4S single cluster domain 32 117 1.9E-5 T 28-03-2018 CNX65_RS02390 839a1c0f51a4180d7bdba93a71ea1813 341 SMART SM00729 25 221 3.3E-6 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS25250 d2c05e630d4ce2b1065236707d1cae8d 112 SUPERFAMILY SSF69118 1 110 3.01E-32 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS25250 d2c05e630d4ce2b1065236707d1cae8d 112 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 106 8.5E-25 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS25250 d2c05e630d4ce2b1065236707d1cae8d 112 Gene3D G3DSA:1.20.1290.10 2 112 3.4E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 Gene3D G3DSA:3.20.20.80 2 335 1.0E-54 T 28-03-2018 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 SUPERFAMILY SSF51445 3 342 3.1E-87 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 Gene3D G3DSA:2.60.40.1500 336 485 3.4E-38 T 28-03-2018 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 PRINTS PR00745 Glycosyl hydrolase family 39 signature 70 86 4.5E-31 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 PRINTS PR00745 Glycosyl hydrolase family 39 signature 271 288 4.5E-31 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 PRINTS PR00745 Glycosyl hydrolase family 39 signature 198 212 4.5E-31 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 PRINTS PR00745 Glycosyl hydrolase family 39 signature 117 134 4.5E-31 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 PRINTS PR00745 Glycosyl hydrolase family 39 signature 134 150 4.5E-31 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 PRINTS PR00745 Glycosyl hydrolase family 39 signature 413 427 4.5E-31 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 Pfam PF01229 Glycosyl hydrolases family 39 4 466 9.3E-126 T 28-03-2018 IPR000514 Glycoside hydrolase, family 39 GO:0004553|GO:0005975 Reactome: R-HSA-2024096|Reactome: R-HSA-2024101 CNX65_RS09875 398bc6ae1833a57ddd8ca9af2a9b26b4 497 SUPERFAMILY SSF51011 330 478 2.88E-24 T 28-03-2018 CNX65_RS30470 f9dc5816b9c0cbb8de1e59d3d81c7a4e 402 Pfam PF00480 ROK family 145 374 9.2E-35 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS30470 f9dc5816b9c0cbb8de1e59d3d81c7a4e 402 Gene3D G3DSA:3.30.420.40 73 184 1.8E-13 T 28-03-2018 CNX65_RS30470 f9dc5816b9c0cbb8de1e59d3d81c7a4e 402 Gene3D G3DSA:1.10.10.10 9 72 1.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30470 f9dc5816b9c0cbb8de1e59d3d81c7a4e 402 SUPERFAMILY SSF53067 81 375 4.94E-37 T 28-03-2018 CNX65_RS30470 f9dc5816b9c0cbb8de1e59d3d81c7a4e 402 SUPERFAMILY SSF46785 13 73 1.56E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30470 f9dc5816b9c0cbb8de1e59d3d81c7a4e 402 Gene3D G3DSA:3.30.420.40 185 381 5.3E-40 T 28-03-2018 CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 Pfam PF00270 DEAD/DEAH box helicase 33 178 3.3E-12 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 SUPERFAMILY SSF52540 44 250 3.92E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 SUPERFAMILY SSF52540 283 375 3.92E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 SMART SM00490 277 363 2.3E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 Pfam PF12029 Domain of unknown function (DUF3516) 374 821 2.6E-212 T 28-03-2018 IPR021904 Protein of unknown function DUF3516 CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 Gene3D G3DSA:3.40.50.300 19 201 5.0E-28 T 28-03-2018 CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 SMART SM00487 27 212 2.2E-18 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 Gene3D G3DSA:3.40.50.300 212 406 8.4E-19 T 28-03-2018 CNX65_RS26245 7e50cc7e6fb71d19d5318e8671e3397b 827 Pfam PF00271 Helicase conserved C-terminal domain 284 363 5.5E-6 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS25770 0c60046faec0b8bab8ad03fe853ac023 215 SUPERFAMILY SSF51182 76 200 1.03E-6 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS25770 0c60046faec0b8bab8ad03fe853ac023 215 Gene3D G3DSA:2.60.120.10 60 207 2.3E-6 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS20180 fdcb9eb701dfa0a0224aca119fb3e414 533 SUPERFAMILY SSF50370 406 531 3.47E-31 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20180 fdcb9eb701dfa0a0224aca119fb3e414 533 Gene3D G3DSA:2.80.10.50 202 449 3.2E-13 T 28-03-2018 CNX65_RS20180 fdcb9eb701dfa0a0224aca119fb3e414 533 Pfam PF00652 Ricin-type beta-trefoil lectin domain 409 530 3.4E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20180 fdcb9eb701dfa0a0224aca119fb3e414 533 Gene3D G3DSA:2.80.10.50 450 532 3.7E-21 T 28-03-2018 CNX65_RS20180 fdcb9eb701dfa0a0224aca119fb3e414 533 SMART SM00458 406 533 3.4E-29 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20180 fdcb9eb701dfa0a0224aca119fb3e414 533 Pfam PF16483 Beta-1,3-glucanase 37 394 1.7E-105 T 28-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 SUPERFAMILY SSF56601 52 311 1.71E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 PRINTS PR00118 Beta-lactamase class A signature 192 217 7.9E-62 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 PRINTS PR00118 Beta-lactamase class A signature 166 190 7.9E-62 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 PRINTS PR00118 Beta-lactamase class A signature 83 100 7.9E-62 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 PRINTS PR00118 Beta-lactamase class A signature 229 244 7.9E-62 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 PRINTS PR00118 Beta-lactamase class A signature 52 76 7.9E-62 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 PRINTS PR00118 Beta-lactamase class A signature 123 148 7.9E-62 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 PRINTS PR00118 Beta-lactamase class A signature 246 261 7.9E-62 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 Pfam PF13354 Beta-lactamase enzyme family 73 286 9.1E-32 T 28-03-2018 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 Gene3D G3DSA:3.40.710.10 50 314 5.8E-34 T 28-03-2018 CNX65_RS19820 ab74fcfda463772e0f4ac4a9b0821547 314 ProSitePatterns PS00146 Beta-lactamase class-A active site. 85 100 - T 28-03-2018 IPR023650 Beta-lactamase, class-A active site KEGG: 00311+3.5.2.6 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 SMART SM00776 522 667 1.7E-65 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 Gene3D G3DSA:3.20.20.70 19 182 8.5E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 Gene3D G3DSA:2.60.40.1180 308 412 8.4E-25 T 28-03-2018 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 425 497 1.7E-12 T 28-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 Pfam PF16499 Alpha galactosidase A 40 307 1.2E-78 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 Gene3D G3DSA:2.60.40.10 422 517 0.0017 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 Gene3D G3DSA:3.20.20.70 183 307 2.1E-53 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 SUPERFAMILY SSF49785 524 667 1.62E-41 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 PRINTS PR00740 Glycosyl hydrolase family 27 signature 263 284 3.4E-59 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 PRINTS PR00740 Glycosyl hydrolase family 27 signature 35 54 3.4E-59 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 PRINTS PR00740 Glycosyl hydrolase family 27 signature 150 167 3.4E-59 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 PRINTS PR00740 Glycosyl hydrolase family 27 signature 73 88 3.4E-59 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 PRINTS PR00740 Glycosyl hydrolase family 27 signature 177 195 3.4E-59 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 PRINTS PR00740 Glycosyl hydrolase family 27 signature 242 261 3.4E-59 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 PRINTS PR00740 Glycosyl hydrolase family 27 signature 114 135 3.4E-59 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 Pfam PF08305 NPCBM/NEW2 domain 525 664 3.1E-44 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 SUPERFAMILY SSF51011 309 396 1.56E-20 T 28-03-2018 CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 SUPERFAMILY SSF51445 32 308 1.09E-97 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS05240 915ccee73d24de54522a996d8b331fa1 668 ProSitePatterns PS00512 Alpha-galactosidase signature. 78 94 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS10825 3a14f92d7236757d94eb189f1b716851 248 Hamap MF_02036 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase [egtC]. 1 245 37.281 T 28-03-2018 IPR032889 Gamma-glutamyl-hercynylcysteine sulfoxide hydrolase, Actinobacteria GO:0016811|GO:0052699 CNX65_RS10825 3a14f92d7236757d94eb189f1b716851 248 Pfam PF13522 Glutamine amidotransferase domain 75 216 3.6E-17 T 28-03-2018 CNX65_RS10825 3a14f92d7236757d94eb189f1b716851 248 Gene3D G3DSA:3.60.20.10 2 246 7.0E-26 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS10825 3a14f92d7236757d94eb189f1b716851 248 SUPERFAMILY SSF56235 2 240 4.17E-20 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS10825 3a14f92d7236757d94eb189f1b716851 248 TIGRFAM TIGR03442 TIGR03442: ergothioneine biosynthesis protein EgtC 1 245 9.9E-79 T 28-03-2018 IPR017808 Ergothioneine biosynthesis protein EgtC GO:0052699 CNX65_RS32230 276d46ec262cd15c73a6ce1b2840cdc3 105 Pfam PF06013 Proteins of 100 residues with WXG 9 88 4.8E-16 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS32230 276d46ec262cd15c73a6ce1b2840cdc3 105 Gene3D G3DSA:1.10.287.1060 1 97 2.3E-18 T 28-03-2018 CNX65_RS32230 276d46ec262cd15c73a6ce1b2840cdc3 105 SUPERFAMILY SSF140453 5 95 2.49E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS32230 276d46ec262cd15c73a6ce1b2840cdc3 105 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 7 92 1.8E-18 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 330 364 2.7E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 408 441 1.6E-5 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 280 312 1.1E-4 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 8 465 39.533 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 SUPERFAMILY SSF51161 262 451 1.09E-38 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 SUPERFAMILY SSF53448 11 266 2.38E-59 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 Pfam PF12804 MobA-like NTP transferase domain 12 145 5.2E-19 T 28-03-2018 IPR025877 MobA-like NTP transferase CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 Gene3D G3DSA:3.90.550.10 6 265 1.6E-58 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 10 465 1.7E-164 T 28-03-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|KEGG: 00561+2.3.1.15|KEGG: 00564+2.3.1.15|MetaCyc: PWY-5514|MetaCyc: PWY-5667|MetaCyc: PWY-6453|MetaCyc: PWY-7411|MetaCyc: PWY-7587 CNX65_RS03255 7a957dda630a7bbf9024b0b80a9b738e 491 Gene3D G3DSA:2.160.10.10 266 453 2.6E-42 T 28-03-2018 CNX65_RS23575 9d9c80e0a28304e6a20ef6edbc15509d 267 SMART SM00382 42 227 3.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS23575 9d9c80e0a28304e6a20ef6edbc15509d 267 Pfam PF00005 ABC transporter 43 179 2.4E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS23575 9d9c80e0a28304e6a20ef6edbc15509d 267 SUPERFAMILY SSF52540 18 238 7.61E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23575 9d9c80e0a28304e6a20ef6edbc15509d 267 Gene3D G3DSA:3.40.50.300 17 247 2.2E-59 T 28-03-2018 CNX65_RS24645 710d0afe019a93f3e04a4aceb703a3cb 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 137 1.9E-23 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS24645 710d0afe019a93f3e04a4aceb703a3cb 346 SUPERFAMILY SSF51735 151 310 1.93E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24645 710d0afe019a93f3e04a4aceb703a3cb 346 Gene3D G3DSA:3.40.50.10730 166 302 4.9E-23 T 28-03-2018 CNX65_RS24645 710d0afe019a93f3e04a4aceb703a3cb 346 SUPERFAMILY SSF50129 1 172 1.05E-44 T 28-03-2018 IPR011032 GroES-like CNX65_RS24645 710d0afe019a93f3e04a4aceb703a3cb 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS24645 710d0afe019a93f3e04a4aceb703a3cb 346 Pfam PF00107 Zinc-binding dehydrogenase 182 300 5.6E-19 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS24645 710d0afe019a93f3e04a4aceb703a3cb 346 Gene3D G3DSA:3.90.180.10 1 165 3.6E-39 T 28-03-2018 CNX65_RS20430 4cb283a7997282c1bfe01909139d1e11 336 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 221 2.2E-28 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS20430 4cb283a7997282c1bfe01909139d1e11 336 SUPERFAMILY SSF51735 1 265 3.32E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20430 4cb283a7997282c1bfe01909139d1e11 336 SUPERFAMILY SSF51735 291 326 3.32E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20430 4cb283a7997282c1bfe01909139d1e11 336 Gene3D G3DSA:3.40.50.720 2 328 1.6E-49 T 28-03-2018 CNX65_RS20430 4cb283a7997282c1bfe01909139d1e11 336 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS27605 34c308c9a7d9ce7fb6343f1257fc4029 131 SMART SM00881 5 97 1.4E-21 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS27605 34c308c9a7d9ce7fb6343f1257fc4029 131 Gene3D G3DSA:3.40.50.720 6 127 5.3E-29 T 28-03-2018 CNX65_RS27605 34c308c9a7d9ce7fb6343f1257fc4029 131 SUPERFAMILY SSF51735 2 125 3.94E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27605 34c308c9a7d9ce7fb6343f1257fc4029 131 Pfam PF13380 CoA binding domain 9 123 5.9E-38 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 Gene3D G3DSA:3.40.50.1370 1 163 7.9E-58 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 136 147 1.1E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 257 266 1.1E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 269 292 1.1E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 49 68 1.1E-18 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 157 302 4.6E-20 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 135 152 3.0E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 3.0E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 285 299 3.0E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 39 61 3.0E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 220 229 3.0E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 PRINTS PR00101 Aspartate carbamoyltransferase signature 261 266 3.0E-30 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 149 1.5E-37 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 304 5.8E-81 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 49 56 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 SUPERFAMILY SSF53671 2 305 2.36E-90 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 Gene3D G3DSA:3.40.50.1370 164 306 3.8E-42 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS26105 18e1f72d20f7c4bd37eff2f68fca5c91 311 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 306 38.075 T 28-03-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS18145 1b8c5fee4f2a1ceeb7be43f4516313ea 315 PIRSF PIRSF001439 4 314 5.9E-49 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CNX65_RS18145 1b8c5fee4f2a1ceeb7be43f4516313ea 315 Gene3D G3DSA:3.30.1780.10 3 137 1.4E-35 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CNX65_RS18145 1b8c5fee4f2a1ceeb7be43f4516313ea 315 SUPERFAMILY SSF51735 7 313 1.67E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18145 1b8c5fee4f2a1ceeb7be43f4516313ea 315 Gene3D G3DSA:3.40.50.720 138 297 2.4E-18 T 28-03-2018 CNX65_RS18145 1b8c5fee4f2a1ceeb7be43f4516313ea 315 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 9 313 4.3E-39 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 SUPERFAMILY SSF51621 246 522 7.85E-84 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 59 521 3.9E-104 T 28-03-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 SUPERFAMILY SSF52009 123 225 1.44E-28 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 Pfam PF00391 PEP-utilising enzyme, mobile domain 150 221 8.8E-23 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 247 513 1.3E-76 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 Pfam PF05524 PEP-utilising enzyme, N-terminal 8 124 2.4E-18 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 182 193 - T 28-03-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 Gene3D G3DSA:3.20.20.60 297 517 1.9E-69 T 28-03-2018 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 Gene3D G3DSA:1.10.274.10 30 143 4.6E-22 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 PIRSF PIRSF000732 1 541 1.6E-142 T 28-03-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 421 436 3.5E-18 T 28-03-2018 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 438 453 3.5E-18 T 28-03-2018 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 474 486 3.5E-18 T 28-03-2018 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 277 296 3.5E-18 T 28-03-2018 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 Gene3D G3DSA:3.50.30.10 144 261 4.4E-25 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 Gene3D G3DSA:3.20.20.60 262 296 1.8E-10 T 28-03-2018 CNX65_RS34915 a112f92fa64eff2e0de062948c6064b9 543 SUPERFAMILY SSF47831 35 141 2.35E-19 T 28-03-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 SMART SM00829 10 342 3.5E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 Gene3D G3DSA:3.40.50.10730 166 299 5.9E-25 T 28-03-2018 CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 SUPERFAMILY SSF50129 1 179 8.95E-42 T 28-03-2018 IPR011032 GroES-like CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 139 1.5E-29 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 SUPERFAMILY SSF51735 142 312 4.45E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 Gene3D G3DSA:3.90.180.10 1 165 2.7E-43 T 28-03-2018 CNX65_RS15995 14d85c2f28d9d96357f262e45868308f 346 Pfam PF00107 Zinc-binding dehydrogenase 182 283 4.7E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 PIRSF PIRSF036382 3 200 1.0E-72 T 28-03-2018 IPR008327 Signal transduction response regulator, antiterminator CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 Gene3D G3DSA:1.10.10.10 145 198 5.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 Gene3D G3DSA:3.40.50.2300 1 143 2.4E-34 T 28-03-2018 CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 SMART SM00448 14 125 2.3E-35 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 Pfam PF00072 Response regulator receiver domain 16 125 7.7E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 SUPERFAMILY SSF52172 9 196 1.99E-56 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 Pfam PF03861 ANTAR domain 145 196 6.1E-21 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS27585 d61633d5a7074bd5886ea4617eeec569 200 SMART SM01012 141 196 3.0E-24 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 SUPERFAMILY SSF46785 1 110 1.78E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 Gene3D G3DSA:3.40.190.10 86 170 1.6E-17 T 28-03-2018 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.6E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 SUPERFAMILY SSF53850 87 271 6.36E-32 T 28-03-2018 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 Gene3D G3DSA:1.10.10.10 1 85 5.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 Gene3D G3DSA:3.40.190.10 171 248 1.0E-8 T 28-03-2018 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 6.6E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02795 ffa7e2e8d49b5358f6643ed7a163d97b 272 Pfam PF03466 LysR substrate binding domain 86 271 6.9E-35 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 Gene3D G3DSA:1.10.1740.10 1 88 6.2E-14 T 28-03-2018 CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 SUPERFAMILY SSF88946 2 89 1.88E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 155 1.2E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 Gene3D G3DSA:1.10.10.10 96 161 2.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 SUPERFAMILY SSF88659 99 156 2.62E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 Pfam PF04545 Sigma-70, region 4 104 153 4.6E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 155 4.9E-43 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CNX65_RS02195 22a9b800aca8996ca1154b20e992e7f8 174 Pfam PF04542 Sigma-70 region 2 18 75 3.2E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS19810 6686b369e793ee7c25d32e025815bb0e 300 Gene3D G3DSA:3.40.710.10 1 296 9.8E-31 T 28-03-2018 CNX65_RS19810 6686b369e793ee7c25d32e025815bb0e 300 Pfam PF13354 Beta-lactamase enzyme family 28 267 7.7E-44 T 28-03-2018 CNX65_RS19810 6686b369e793ee7c25d32e025815bb0e 300 SUPERFAMILY SSF56601 6 152 3.25E-33 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS19810 6686b369e793ee7c25d32e025815bb0e 300 SUPERFAMILY SSF56601 184 273 3.25E-33 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 Pfam PF00072 Response regulator receiver domain 4 113 5.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 SUPERFAMILY SSF46894 132 212 3.13E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 Gene3D G3DSA:1.10.10.10 125 214 3.0E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 SMART SM00421 149 206 2.5E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 5.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 5.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 5.9E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 SUPERFAMILY SSF52172 2 132 1.99E-32 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 Gene3D G3DSA:3.40.50.2300 1 124 2.4E-33 T 28-03-2018 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 SMART SM00448 2 113 7.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS30690 d7503d271f23228bbe9f376e721cb8a1 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 205 1.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 Gene3D G3DSA:3.90.180.10 242 329 4.5E-5 T 28-03-2018 CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 SMART SM00829 10 327 4.3E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 94 7.2E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 SUPERFAMILY SSF51735 122 276 1.04E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 SUPERFAMILY SSF50129 1 146 1.29E-37 T 28-03-2018 IPR011032 GroES-like CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 Gene3D G3DSA:3.90.180.10 1 171 4.3E-49 T 28-03-2018 CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 Gene3D G3DSA:3.40.50.720 172 241 9.1E-19 T 28-03-2018 CNX65_RS02140 80a9acbf6da6cb116f88d8d46d4aa4ac 330 Pfam PF13602 Zinc-binding dehydrogenase 207 327 4.8E-25 T 28-03-2018 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 Pfam PF00035 Double-stranded RNA binding motif 170 235 2.3E-16 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 ProSitePatterns PS00517 Ribonuclease III family signature. 49 57 - T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 Gene3D G3DSA:3.30.160.20 168 244 1.1E-22 T 28-03-2018 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 Gene3D G3DSA:1.10.1520.10 22 163 1.1E-37 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 Pfam PF14622 Ribonuclease-III-like 25 153 6.2E-34 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 SMART SM00535 27 163 1.1E-50 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 SMART SM00358 170 236 1.7E-24 T 28-03-2018 IPR014720 Double-stranded RNA-binding domain CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 25 233 6.0E-68 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 Hamap MF_00104 Ribonuclease 3 [rnc]. 16 232 29.65 T 28-03-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 SUPERFAMILY SSF69065 14 171 1.52E-44 T 28-03-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 CNX65_RS29285 697758e9f41c3dfd2e805b50a6817d8b 258 SUPERFAMILY SSF54768 124 235 6.29E-26 T 28-03-2018 CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 Hamap MF_00082_B Acetylglutamate kinase [argB]. 27 293 34.018 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 PRINTS PR00474 Glutamate 5-kinase family signature 243 263 8.7E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 PRINTS PR00474 Glutamate 5-kinase family signature 192 219 8.7E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 PRINTS PR00474 Glutamate 5-kinase family signature 60 74 8.7E-8 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 TIGRFAM TIGR00761 argB: acetylglutamate kinase 30 268 5.5E-74 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 Gene3D G3DSA:3.40.1160.10 1 297 7.8E-71 T 28-03-2018 CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 SUPERFAMILY SSF53633 8 294 1.31E-84 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 Pfam PF00696 Amino acid kinase family 30 270 3.9E-41 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS27175 7301857c94aa863edbb394d5b7196d63 300 PIRSF PIRSF000728 14 293 3.0E-99 T 28-03-2018 IPR004662 Acetylglutamate kinase GO:0003991|GO:0005737|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS01760 599706a6500fe7212928870059cdedff 285 Pfam PF00633 Helix-hairpin-helix motif 91 119 2.9E-8 T 28-03-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 CNX65_RS01760 599706a6500fe7212928870059cdedff 285 Gene3D G3DSA:1.10.340.30 11 108 1.9E-30 T 28-03-2018 CNX65_RS01760 599706a6500fe7212928870059cdedff 285 SUPERFAMILY SSF48150 3 210 6.12E-62 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS01760 599706a6500fe7212928870059cdedff 285 SMART SM00525 183 203 0.0068 T 28-03-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 CNX65_RS01760 599706a6500fe7212928870059cdedff 285 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 26 147 8.6E-16 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CNX65_RS01760 599706a6500fe7212928870059cdedff 285 Gene3D G3DSA:1.10.1670.10 109 216 1.3E-32 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CNX65_RS01760 599706a6500fe7212928870059cdedff 285 SMART SM00478 30 182 5.1E-42 T 28-03-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 189 199 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Gene3D G3DSA:3.40.50.200 122 392 3.1E-71 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 339 349 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Pfam PF05922 Peptidase inhibitor I9 47 113 5.5E-8 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Pfam PF05345 Putative Ig domain 430 466 3.0E-6 T 28-03-2018 IPR008009 Putative Ig CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Pfam PF01483 Proprotein convertase P-domain 518 596 1.2E-19 T 28-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 SUPERFAMILY SSF49785 479 595 6.38E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 SUPERFAMILY SSF49313 411 480 2.98E-6 T 28-03-2018 IPR015919 Cadherin-like GO:0005509|GO:0016020 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 PRINTS PR00723 Subtilisin serine protease family (S8) signature 185 198 6.1E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 PRINTS PR00723 Subtilisin serine protease family (S8) signature 149 168 6.1E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 PRINTS PR00723 Subtilisin serine protease family (S8) signature 338 354 6.1E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Gene3D G3DSA:2.60.120.260 483 597 1.2E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Pfam PF00082 Subtilase family 159 376 9.3E-34 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 SUPERFAMILY SSF54897 45 116 1.19E-11 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 SUPERFAMILY SSF52743 122 376 6.15E-69 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 154 165 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Gene3D G3DSA:2.60.40.10 393 481 6.7E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS11215 7524a049895ac435ca8c7dcf3ed5461a 597 Gene3D G3DSA:3.30.70.80 38 121 5.4E-19 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.6E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 Pfam PF00106 short chain dehydrogenase 5 190 1.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 5.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 5.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.9E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 PIRSF PIRSF000126 2 258 1.4E-73 T 28-03-2018 CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 Gene3D G3DSA:3.40.50.720 1 256 7.8E-53 T 28-03-2018 CNX65_RS34295 64e6003c3ab20abf5f2a220d62402054 259 SUPERFAMILY SSF51735 4 221 3.89E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19060 3fcaa3fbfa2a53cf874ffd6dce90eebb 310 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 175 200 - T 28-03-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 CNX65_RS19060 3fcaa3fbfa2a53cf874ffd6dce90eebb 310 Pfam PF00494 Squalene/phytoene synthase 30 292 8.4E-69 T 28-03-2018 IPR002060 Squalene/phytoene synthase GO:0009058|GO:0016740 CNX65_RS19060 3fcaa3fbfa2a53cf874ffd6dce90eebb 310 SUPERFAMILY SSF48576 19 306 4.24E-77 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS19060 3fcaa3fbfa2a53cf874ffd6dce90eebb 310 Gene3D G3DSA:1.10.600.10 8 307 3.7E-99 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS05820 582b84507b71ea0b260d00f20d39422e 292 Pfam PF12686 Protein of unknown function (DUF3800) 13 216 9.7E-17 T 28-03-2018 IPR024524 Protein of unknown function DUF3800 CNX65_RS04085 1b88a7b01a10fc873d1fe27fefeff3db 271 SUPERFAMILY SSF46689 14 96 9.22E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS04085 1b88a7b01a10fc873d1fe27fefeff3db 271 Gene3D G3DSA:1.10.357.10 71 213 1.6E-21 T 28-03-2018 CNX65_RS04085 1b88a7b01a10fc873d1fe27fefeff3db 271 Pfam PF00440 Bacterial regulatory proteins, tetR family 28 72 4.7E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS04085 1b88a7b01a10fc873d1fe27fefeff3db 271 SUPERFAMILY SSF48498 94 206 7.95E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS04085 1b88a7b01a10fc873d1fe27fefeff3db 271 Gene3D G3DSA:1.10.10.60 2 70 3.8E-17 T 28-03-2018 CNX65_RS16475 8fc48115bf24d282af677fe6fec26e85 540 PIRSF PIRSF001294 3 540 4.8E-203 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CNX65_RS16475 8fc48115bf24d282af677fe6fec26e85 540 Pfam PF03814 Potassium-transporting ATPase A subunit 13 539 1.5E-213 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CNX65_RS16475 8fc48115bf24d282af677fe6fec26e85 540 TIGRFAM TIGR00680 kdpA: K+-transporting ATPase, A subunit 6 539 2.3E-195 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CNX65_RS16475 8fc48115bf24d282af677fe6fec26e85 540 Hamap MF_00275 Potassium-transporting ATPase potassium-binding subunit [kdpA]. 4 540 31.56 T 28-03-2018 IPR004623 Potassium-transporting ATPase A chain GO:0005886|GO:0006813|GO:0008556 CNX65_RS16905 f9eacc0de08e59a57080e26611c1a29c 382 SUPERFAMILY SSF53383 19 376 6.27E-84 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS16905 f9eacc0de08e59a57080e26611c1a29c 382 Gene3D G3DSA:3.90.1150.10 280 375 1.1E-28 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS16905 f9eacc0de08e59a57080e26611c1a29c 382 Pfam PF00266 Aminotransferase class-V 41 337 8.3E-26 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS16905 f9eacc0de08e59a57080e26611c1a29c 382 TIGRFAM TIGR03301 PhnW-AepZ: 2-aminoethylphosphonate aminotransferase 19 370 2.6E-109 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CNX65_RS16905 f9eacc0de08e59a57080e26611c1a29c 382 Gene3D G3DSA:3.40.640.10 26 279 3.7E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS16905 f9eacc0de08e59a57080e26611c1a29c 382 PIRSF PIRSF000524 13 382 5.1E-83 T 28-03-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661 CNX65_RS16905 f9eacc0de08e59a57080e26611c1a29c 382 Hamap MF_01376 2-aminoethylphosphonate--pyruvate transaminase [phnW]. 1 380 112.637 T 28-03-2018 IPR012703 2-aminoethylphosphonate--pyruvate transaminase GO:0019700|GO:0047304 KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 Gene3D G3DSA:2.70.150.10 12 233 7.3E-29 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 82 631 1.4E-171 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 82 633 1.6E-146 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 334 340 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 106 592 5.2E-71 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 Gene3D G3DSA:3.40.1110.10 344 454 4.1E-29 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 SUPERFAMILY SSF81665 233 326 1.83E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 SUPERFAMILY SSF81665 84 136 1.83E-12 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 500 516 4.5E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 528 544 4.5E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 560 585 4.5E-7 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 Pfam PF00702 haloacid dehalogenase-like hydrolase 331 541 3.9E-42 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 Gene3D G3DSA:3.40.50.1000 455 595 2.2E-35 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 Pfam PF00122 E1-E2 ATPase 133 311 7.2E-48 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 SUPERFAMILY SSF81653 135 231 1.96E-24 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 SUPERFAMILY SSF81660 346 462 1.73E-27 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 182 196 4.7E-23 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 547 4.7E-23 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 475 485 4.7E-23 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 452 463 4.7E-23 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 332 346 4.7E-23 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 552 564 4.7E-23 T 28-03-2018 CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 SUPERFAMILY SSF56784 443 628 4.21E-50 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS21450 4b44932570c46af757c187be7a2da9d4 642 SUPERFAMILY SSF56784 331 350 4.21E-50 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS00970 794844e3a04c37a7966fe3a470e03269 336 SUPERFAMILY SSF161098 92 161 2.94E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS00970 794844e3a04c37a7966fe3a470e03269 336 SUPERFAMILY SSF161098 198 319 2.94E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS00970 794844e3a04c37a7966fe3a470e03269 336 Gene3D G3DSA:1.10.3720.10 2 323 7.6E-44 T 28-03-2018 CNX65_RS00970 794844e3a04c37a7966fe3a470e03269 336 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 115 334 9.9E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS23070 7003e9111264e175b64763002205df58 333 Gene3D G3DSA:1.10.1660.10 57 122 6.8E-5 T 28-03-2018 CNX65_RS23070 7003e9111264e175b64763002205df58 333 SUPERFAMILY SSF48371 113 327 5.76E-21 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS23070 7003e9111264e175b64763002205df58 333 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS23070 7003e9111264e175b64763002205df58 333 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS23070 7003e9111264e175b64763002205df58 333 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.1E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS23070 7003e9111264e175b64763002205df58 333 Pfam PF13646 HEAT repeats 178 263 6.3E-13 T 28-03-2018 CNX65_RS23070 7003e9111264e175b64763002205df58 333 Gene3D G3DSA:1.10.1660.10 1 56 6.1E-20 T 28-03-2018 CNX65_RS23070 7003e9111264e175b64763002205df58 333 SUPERFAMILY SSF46955 3 102 1.68E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS23070 7003e9111264e175b64763002205df58 333 Pfam PF13411 MerR HTH family regulatory protein 3 68 8.9E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS23070 7003e9111264e175b64763002205df58 333 SMART SM00567 E-Z type HEAT repeats 286 315 80.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS23070 7003e9111264e175b64763002205df58 333 SMART SM00567 E-Z type HEAT repeats 189 219 0.11 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS23070 7003e9111264e175b64763002205df58 333 SMART SM00567 E-Z type HEAT repeats 221 250 290.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS23070 7003e9111264e175b64763002205df58 333 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS23070 7003e9111264e175b64763002205df58 333 Gene3D G3DSA:1.25.10.10 123 329 5.4E-12 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS23070 7003e9111264e175b64763002205df58 333 SMART SM00422 1 70 8.8E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Gene3D G3DSA:3.40.10.10 2 73 1.8E-26 T 28-03-2018 IPR035451 Ada-like domain CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Gene3D G3DSA:3.30.310.20 199 309 1.8E-40 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Pfam PF06029 AlkA N-terminal domain 197 311 1.6E-34 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 SUPERFAMILY SSF48150 350 418 2.09E-8 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 SMART SM00342 100 183 8.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 SMART SM01009 196 311 5.0E-51 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Gene3D G3DSA:1.10.10.60 144 198 1.8E-8 T 28-03-2018 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Pfam PF12833 Helix-turn-helix domain 106 184 2.0E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Gene3D G3DSA:1.10.10.60 82 143 7.4E-5 T 28-03-2018 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Gene3D G3DSA:1.10.1670.10 310 420 8.2E-4 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 Pfam PF02805 Metal binding domain of Ada 8 71 1.5E-27 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 SUPERFAMILY SSF57884 2 84 1.96E-30 T 28-03-2018 IPR004026 Ada DNA repair, metal-binding GO:0003677|GO:0006281|GO:0006355|GO:0008168|GO:0008270 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 SUPERFAMILY SSF46689 137 186 8.51E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 137 179 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS03660 759af510dd5ae0a6424e402afeffb5ca 441 SUPERFAMILY SSF55945 197 292 1.73E-27 T 28-03-2018 CNX65_RS33095 9ceff8325f0b1b0e4537cc19df24cb3d 324 SMART SM00829 21 321 8.1E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS33095 9ceff8325f0b1b0e4537cc19df24cb3d 324 SUPERFAMILY SSF51735 132 256 5.78E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS33095 9ceff8325f0b1b0e4537cc19df24cb3d 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 38 103 1.8E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS33095 9ceff8325f0b1b0e4537cc19df24cb3d 324 SUPERFAMILY SSF50129 11 165 5.48E-38 T 28-03-2018 IPR011032 GroES-like CNX65_RS33095 9ceff8325f0b1b0e4537cc19df24cb3d 324 Gene3D G3DSA:3.90.180.10 11 205 4.0E-51 T 28-03-2018 CNX65_RS33095 9ceff8325f0b1b0e4537cc19df24cb3d 324 Gene3D G3DSA:3.90.180.10 206 324 2.7E-6 T 28-03-2018 CNX65_RS33095 9ceff8325f0b1b0e4537cc19df24cb3d 324 Pfam PF13602 Zinc-binding dehydrogenase 201 321 1.1E-13 T 28-03-2018 CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 SUPERFAMILY SSF56645 1 270 7.59E-75 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 4 268 7.3E-93 T 28-03-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 Gene3D G3DSA:1.20.140.10 280 479 2.0E-60 T 28-03-2018 CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 SUPERFAMILY SSF47203 260 479 1.49E-47 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 Gene3D G3DSA:2.40.110.10 142 271 2.2E-17 T 28-03-2018 CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 276 478 7.5E-55 T 28-03-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 PIRSF PIRSF000331 1 484 2.4E-142 T 28-03-2018 IPR004925 HpaB/PvcC/4-BUDH CNX65_RS18390 7f1b220b886d85da72bbc1d8af2aa861 486 Gene3D G3DSA:1.10.3140.10 2 141 3.3E-40 T 28-03-2018 CNX65_RS25395 f72880abda0cd0e27a066d059361c2cc 57 Pfam PF05532 CsbD-like 5 57 1.6E-17 T 28-03-2018 IPR008462 CsbD-like domain CNX65_RS25395 f72880abda0cd0e27a066d059361c2cc 57 Gene3D G3DSA:1.10.1470.10 3 57 9.3E-15 T 28-03-2018 IPR008462 CsbD-like domain CNX65_RS25395 f72880abda0cd0e27a066d059361c2cc 57 SUPERFAMILY SSF69047 5 56 9.55E-10 T 28-03-2018 IPR008462 CsbD-like domain CNX65_RS13700 7bcc8a072efa1c666b378cf63794ea0f 352 SUPERFAMILY SSF53807 63 345 3.18E-44 T 28-03-2018 CNX65_RS13700 7bcc8a072efa1c666b378cf63794ea0f 352 Gene3D G3DSA:3.40.50.1980 184 347 1.1E-33 T 28-03-2018 CNX65_RS13700 7bcc8a072efa1c666b378cf63794ea0f 352 Gene3D G3DSA:3.40.50.1980 40 183 5.5E-35 T 28-03-2018 CNX65_RS13700 7bcc8a072efa1c666b378cf63794ea0f 352 Pfam PF01497 Periplasmic binding protein 68 326 6.1E-37 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS21950 1a048ddf927315879c3480ff97190a57 330 PIRSF PIRSF005739 2 329 5.6E-36 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CNX65_RS21950 1a048ddf927315879c3480ff97190a57 330 Pfam PF00891 O-methyltransferase 106 312 1.3E-36 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CNX65_RS21950 1a048ddf927315879c3480ff97190a57 330 SUPERFAMILY SSF53335 107 329 3.8E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS21950 1a048ddf927315879c3480ff97190a57 330 Gene3D G3DSA:3.40.50.150 84 330 7.6E-35 T 28-03-2018 CNX65_RS21950 1a048ddf927315879c3480ff97190a57 330 SUPERFAMILY SSF46785 10 86 2.85E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21950 1a048ddf927315879c3480ff97190a57 330 Gene3D G3DSA:1.10.10.10 1 82 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 Pfam PF13377 Periplasmic binding protein-like domain 175 336 1.9E-39 T 28-03-2018 CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 Gene3D G3DSA:3.40.50.2300 182 312 5.3E-49 T 28-03-2018 CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 SMART SM00354 13 78 3.0E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 SUPERFAMILY SSF47413 13 61 2.64E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 Gene3D G3DSA:1.10.260.40 14 64 2.0E-16 T 28-03-2018 CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 Gene3D G3DSA:3.40.50.2300 65 181 2.4E-26 T 28-03-2018 CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 SUPERFAMILY SSF53822 69 339 2.06E-71 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS16745 58898753e4c1705bbcfabf677f017945 341 Pfam PF00356 Bacterial regulatory proteins, lacI family 15 58 9.2E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS21925 7af6b5509e4553f8071fb69a0a4ed1e1 264 SUPERFAMILY SSF51735 3 234 1.52E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21925 7af6b5509e4553f8071fb69a0a4ed1e1 264 Gene3D G3DSA:3.40.50.720 2 264 6.4E-39 T 28-03-2018 CNX65_RS21925 7af6b5509e4553f8071fb69a0a4ed1e1 264 Pfam PF00106 short chain dehydrogenase 3 127 1.7E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21925 7af6b5509e4553f8071fb69a0a4ed1e1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 2 19 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21925 7af6b5509e4553f8071fb69a0a4ed1e1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21925 7af6b5509e4553f8071fb69a0a4ed1e1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21925 7af6b5509e4553f8071fb69a0a4ed1e1 264 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 129 1.4E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 Gene3D G3DSA:3.20.20.120 102 380 1.1E-59 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 SUPERFAMILY SSF51604 98 390 1.57E-69 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 Pfam PF13378 Enolase C-terminal domain-like 141 382 4.2E-42 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 SUPERFAMILY SSF54826 8 112 1.5E-31 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 ProSitePatterns PS00908 Mandelate racemase / muconate lactonizing enzyme family signature 1. 85 110 - T 28-03-2018 IPR018110 Mandelate racemase/muconate lactonizing enzyme, conserved site GO:0009063 CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 SMART SM00922 129 262 2.0E-18 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 Gene3D G3DSA:3.30.390.10 1 101 1.9E-30 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS20680 4a56fbcdd716062b6fbf06d51f040fb8 407 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 14 110 5.6E-31 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 906 1058 7.7E-29 T 28-03-2018 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 SMART SM00560 922 1055 7.3E-12 T 28-03-2018 IPR006558 LamG-like jellyroll fold CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 SUPERFAMILY SSF49303 473 565 5.18E-14 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Gene3D G3DSA:3.20.20.80 575 843 7.6E-34 T 28-03-2018 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Gene3D G3DSA:2.60.40.10 471 565 7.3E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 SUPERFAMILY SSF56988 35 185 1.57E-28 T 28-03-2018 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Gene3D G3DSA:2.60.120.200 851 1064 1.6E-40 T 28-03-2018 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Gene3D G3DSA:3.90.182.10 25 240 9.4E-33 T 28-03-2018 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 343 465 1.4E-11 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 SUPERFAMILY SSF49899 865 1062 2.11E-34 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Pfam PF00703 Glycosyl hydrolases family 2 473 564 6.9E-11 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 SUPERFAMILY SSF51445 561 836 7.42E-52 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 SUPERFAMILY SSF49785 299 469 6.56E-46 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Pfam PF07691 PA14 domain 59 175 3.1E-18 T 28-03-2018 IPR011658 PA14 domain CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 Gene3D G3DSA:2.60.120.260 276 470 3.3E-41 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS12505 5f8592f81e0112e9c5272043093a34e9 1064 SMART SM00758 34 176 8.4E-23 T 28-03-2018 IPR011658 PA14 domain CNX65_RS26810 6820e8da724246a233062249ccb1a7ab 602 SUPERFAMILY SSF69255 376 450 2.62E-18 T 28-03-2018 CNX65_RS26810 6820e8da724246a233062249ccb1a7ab 602 SUPERFAMILY SSF69279 32 176 2.27E-13 T 28-03-2018 CNX65_RS26810 6820e8da724246a233062249ccb1a7ab 602 Pfam PF05954 Phage late control gene D protein (GPD) 60 345 5.4E-7 T 28-03-2018 CNX65_RS26810 6820e8da724246a233062249ccb1a7ab 602 Gene3D G3DSA:3.55.50.10 105 191 0.0011 T 28-03-2018 CNX65_RS26810 6820e8da724246a233062249ccb1a7ab 602 Gene3D G3DSA:2.40.50.260 371 472 5.8E-28 T 28-03-2018 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 1.0E-38 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 SMART SM01387 8 88 5.3E-49 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 11 88 7.0E-20 T 28-03-2018 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 Pfam PF00312 Ribosomal protein S15 8 88 4.3E-36 T 28-03-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.114 T 28-03-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 Gene3D G3DSA:1.10.287.10 2 89 1.0E-34 T 28-03-2018 CNX65_RS28565 73f124ecd32ace5e94a4f8286caaeaa9 89 SUPERFAMILY SSF47060 3 89 2.18E-34 T 28-03-2018 IPR009068 S15/NS1, RNA-binding CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 343 362 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 SUPERFAMILY SSF56645 7 247 9.95E-77 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 Gene3D G3DSA:2.40.110.10 125 224 1.8E-38 T 28-03-2018 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 PIRSF PIRSF016578 6 105 1.6E-7 T 28-03-2018 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 PIRSF PIRSF016578 127 386 1.5E-15 T 28-03-2018 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 1.0E-28 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 Gene3D G3DSA:1.20.140.10 225 387 2.6E-63 T 28-03-2018 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 SUPERFAMILY SSF47203 233 386 3.29E-59 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 Gene3D G3DSA:1.10.540.10 1 124 2.0E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 122 4.6E-31 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 384 1.3E-50 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS31260 9c403b6dd8bca3f2de6079e8e152429d 387 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 128 140 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 SUPERFAMILY SSF110921 403 526 6.41E-23 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 SMART SM00917 380 530 1.8E-35 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 TIGRFAM TIGR00977 citramal_synth: citramalate synthase 8 530 1.1E-176 T 28-03-2018 IPR005675 Citramalate synthase GO:0019752|GO:0046912 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 Pfam PF08502 LeuA allosteric (dimerisation) domain 380 527 3.1E-25 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 Pfam PF00682 HMGL-like 10 260 5.4E-39 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 Gene3D G3DSA:3.20.20.70 2 357 3.0E-86 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS29580 6308646a5d80ae2853d79b87f6eaa151 537 SUPERFAMILY SSF51569 4 298 3.48E-71 T 28-03-2018 CNX65_RS10325 daf4c433af25be7f7e45a824122f73af 116 Gene3D G3DSA:1.10.10.10 1 74 4.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10325 daf4c433af25be7f7e45a824122f73af 116 SUPERFAMILY SSF46785 2 74 9.24E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10325 daf4c433af25be7f7e45a824122f73af 116 SMART SM00345 13 72 2.9E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS10325 daf4c433af25be7f7e45a824122f73af 116 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 72 1.3E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS18750 60656a06a69f733f5cffacfccf1a1647 557 Pfam PF05199 GMC oxidoreductase 453 510 1.1E-17 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS18750 60656a06a69f733f5cffacfccf1a1647 557 SUPERFAMILY SSF51905 3 296 1.38E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18750 60656a06a69f733f5cffacfccf1a1647 557 SUPERFAMILY SSF51905 455 515 1.38E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18750 60656a06a69f733f5cffacfccf1a1647 557 Pfam PF00732 GMC oxidoreductase 4 270 3.7E-12 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS18750 60656a06a69f733f5cffacfccf1a1647 557 Gene3D G3DSA:3.50.50.60 1 525 1.2E-57 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Gene3D G3DSA:3.90.1100.10 555 623 1.9E-13 T 28-03-2018 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Gene3D G3DSA:3.90.1100.10 326 554 2.3E-81 T 28-03-2018 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 SUPERFAMILY SSF64484 25 1130 0.0 T 28-03-2018 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Pfam PF04565 RNA polymerase Rpb2, domain 3 422 490 2.0E-28 T 28-03-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Pfam PF04563 RNA polymerase beta subunit 91 407 7.4E-22 T 28-03-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Gene3D G3DSA:2.40.50.100 624 695 1.3E-27 T 28-03-2018 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Gene3D G3DSA:2.40.270.10 789 1029 8.5E-66 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Gene3D G3DSA:2.40.270.10 696 788 1.7E-10 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 ProSitePatterns PS01166 RNA polymerases beta chain signature. 866 878 - T 28-03-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Pfam PF00562 RNA polymerase Rpb2, domain 6 627 1043 9.7E-159 T 28-03-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, domain 6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Pfam PF10385 RNA polymerase beta subunit external 1 domain 500 566 2.9E-25 T 28-03-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Gene3D G3DSA:3.90.1800.10 1046 1090 2.5E-10 T 28-03-2018 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 242 840 0.0 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Gene3D G3DSA:3.90.1110.10 165 325 1.4E-67 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 26 1121 12.298 T 28-03-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Pfam PF04561 RNA polymerase Rpb2, domain 2 168 363 9.5E-29 T 28-03-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32520 eaeb0a952a965a38672c4631432df65d 1160 Pfam PF04560 RNA polymerase Rpb2, domain 7 1045 1119 1.1E-26 T 28-03-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Gene3D G3DSA:1.25.40.10 615 778 4.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 SMART SM01043 109 253 4.0E-39 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Gene3D G3DSA:1.25.40.10 779 1144 8.5E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Gene3D G3DSA:3.40.50.300 275 456 3.3E-11 T 28-03-2018 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 SUPERFAMILY SSF48452 105 274 3.76E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Gene3D G3DSA:1.25.40.10 106 274 1.4E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Pfam PF13191 AAA ATPase domain 281 443 1.1E-16 T 28-03-2018 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 SUPERFAMILY SSF48452 711 887 2.91E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Gene3D G3DSA:1.10.10.10 4 105 2.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Pfam PF00486 Transcriptional regulatory protein, C terminal 29 102 2.0E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 SMART SM00862 22 102 1.3E-15 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 SUPERFAMILY SSF46894 9 102 3.4E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 SUPERFAMILY SSF52540 386 521 2.04E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 SUPERFAMILY SSF52540 274 344 2.04E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14875 21d153cd92546245c1e111597cdfa99b 1145 Pfam PF03704 Bacterial transcriptional activator domain 110 250 3.0E-36 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS16735 7b91e7c6faa6c0ee94795ddc4e4eca5d 502 SUPERFAMILY SSF53850 94 498 1.63E-40 T 28-03-2018 CNX65_RS16735 7b91e7c6faa6c0ee94795ddc4e4eca5d 502 Gene3D G3DSA:3.40.190.10 174 361 4.0E-25 T 28-03-2018 CNX65_RS16735 7b91e7c6faa6c0ee94795ddc4e4eca5d 502 Gene3D G3DSA:3.40.190.10 85 151 0.02 T 28-03-2018 CNX65_RS16735 7b91e7c6faa6c0ee94795ddc4e4eca5d 502 Pfam PF13416 Bacterial extracellular solute-binding protein 142 324 1.5E-9 T 28-03-2018 CNX65_RS24435 c321bd15248ff833a2935fccf56f9928 245 Pfam PF00535 Glycosyl transferase family 2 16 141 4.6E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS24435 c321bd15248ff833a2935fccf56f9928 245 Gene3D G3DSA:3.90.550.10 6 243 1.1E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS24435 c321bd15248ff833a2935fccf56f9928 245 SUPERFAMILY SSF53448 16 215 1.89E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 11 22 3.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 43 3.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 32 3.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 Pfam PF03466 LysR substrate binding domain 83 284 4.4E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 Gene3D G3DSA:1.10.10.10 1 76 3.9E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 Gene3D G3DSA:3.40.190.10 176 264 1.1E-11 T 28-03-2018 CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 SUPERFAMILY SSF53850 84 285 1.29E-23 T 28-03-2018 CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 Gene3D G3DSA:3.40.190.10 84 175 3.1E-16 T 28-03-2018 CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 SUPERFAMILY SSF46785 2 103 6.23E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22830 4dd76f0e88e96a8d01029c2c1d540495 291 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 2 54 1.8E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 Pfam PF07729 FCD domain 104 222 2.3E-19 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 SMART SM00895 102 223 5.5E-18 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 SUPERFAMILY SSF48008 98 231 8.11E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 SMART SM00345 21 82 5.3E-19 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 SUPERFAMILY SSF46785 11 84 4.56E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 70 5.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 54 5.1E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 Gene3D G3DSA:1.20.120.530 91 233 3.4E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 Pfam PF00392 Bacterial regulatory proteins, gntR family 19 76 5.1E-18 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS10625 9c8697edbe2d5d74b9325285c390b0cb 233 Gene3D G3DSA:1.10.10.10 9 84 5.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 SMART SM00331 160 387 2.6E-17 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 Gene3D G3DSA:3.60.40.10 138 388 2.6E-27 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 SUPERFAMILY SSF81606 181 385 4.18E-5 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 SMART SM00448 7 119 2.4E-11 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 190 385 9.1E-42 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 Pfam PF00072 Response regulator receiver domain 9 108 1.6E-12 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 SUPERFAMILY SSF52172 5 145 3.7E-21 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS24815 c691b09aebf9d65374ffe1f17eeffcef 389 Gene3D G3DSA:3.40.50.2300 3 137 1.4E-24 T 28-03-2018 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 SMART SM00637 396 489 4.4E-35 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 Pfam PF00069 Protein kinase domain 12 262 2.8E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 130 142 - T 28-03-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 Gene3D G3DSA:1.10.510.10 79 273 1.0E-48 T 28-03-2018 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 Gene3D G3DSA:3.30.200.20 3 78 6.4E-20 T 28-03-2018 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 PIRSF PIRSF000654 11 269 4.1E-22 T 28-03-2018 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 Gene3D G3DSA:2.60.40.290 387 492 1.2E-31 T 28-03-2018 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 SUPERFAMILY SSF56112 5 289 6.88E-69 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 Pfam PF00553 Cellulose binding domain 396 489 5.5E-24 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 SUPERFAMILY SSF49384 391 490 1.26E-28 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS20895 8397104bc162e679a9fd5d8caed304ac 492 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS18285 9801adf825de8d3dcc15634086f66fac 183 Pfam PF03358 NADPH-dependent FMN reductase 10 148 7.0E-25 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CNX65_RS18285 9801adf825de8d3dcc15634086f66fac 183 SUPERFAMILY SSF52218 9 172 1.84E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS18285 9801adf825de8d3dcc15634086f66fac 183 Gene3D G3DSA:3.40.50.360 9 182 8.4E-25 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 SUPERFAMILY SSF64288 66 245 4.71E-55 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 Gene3D G3DSA:1.10.10.10 4 81 2.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 SMART SM00345 21 78 1.3E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 52 68 6.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 38 52 6.1E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 SUPERFAMILY SSF46785 12 82 5.17E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 Pfam PF07702 UTRA domain 98 238 4.3E-45 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 Gene3D G3DSA:3.40.1410.10 82 247 1.8E-49 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 SMART SM00866 98 238 5.4E-46 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS02075 fe304eb87ecac65f8ade394c54fe146a 249 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 77 5.8E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.9E-23 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 270 286 5.9E-23 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 116 134 5.9E-23 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 5.9E-23 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 297 319 5.9E-23 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 323 1.4E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 119 128 1.8E-13 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 1.8E-13 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 160 185 1.8E-13 T 28-03-2018 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 Pfam PF04324 BFD-like [2Fe-2S] binding domain 380 431 1.5E-8 T 28-03-2018 IPR007419 BFD-like [2Fe-2S]-binding domain CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 Gene3D G3DSA:3.50.50.60 122 265 2.9E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 PIRSF PIRSF037495 1 465 8.5E-125 T 28-03-2018 IPR017224 Opine oxidase, subunit A/hydrogen cyanide synthase, subunit B GO:0016491|GO:0055114 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 SUPERFAMILY SSF51905 3 342 1.3E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 Gene3D G3DSA:3.50.50.60 266 346 2.9E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23515 904c96583a8de0e2793b89a59fcdf21a 467 Gene3D G3DSA:3.50.50.60 1 121 7.4E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS02830 841fda94c9bcf7f20c5e0e5deb5bc2be 220 Pfam PF14016 Protein of unknown function (DUF4232) 85 217 3.6E-29 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CNX65_RS02830 841fda94c9bcf7f20c5e0e5deb5bc2be 220 Gene3D G3DSA:3.40.190.10 1 205 3.4E-4 T 28-03-2018 CNX65_RS31585 1617382947d0068b5f4b3683236bf59a 188 Pfam PF13424 Tetratricopeptide repeat 12 80 8.0E-9 T 28-03-2018 CNX65_RS31585 1617382947d0068b5f4b3683236bf59a 188 Gene3D G3DSA:1.25.40.10 3 127 6.0E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS31585 1617382947d0068b5f4b3683236bf59a 188 SUPERFAMILY SSF48452 9 108 1.27E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 Gene3D G3DSA:3.90.180.10 1 178 1.0E-47 T 28-03-2018 CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 59 73 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 Pfam PF00107 Zinc-binding dehydrogenase 189 257 3.0E-11 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 Gene3D G3DSA:3.40.50.720 179 344 4.2E-31 T 28-03-2018 CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 SMART SM00829 8 310 0.0037 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 SUPERFAMILY SSF51735 156 351 7.27E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 Pfam PF13823 Alcohol dehydrogenase GroES-associated 2 23 1.5E-11 T 28-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 SUPERFAMILY SSF50129 2 175 1.28E-56 T 28-03-2018 IPR011032 GroES-like CNX65_RS09000 e2595c3455497cbe64345f4d620e606b 392 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 140 2.0E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS25855 7cdbed409f70e1a059901f5c5fbb94d6 261 SUPERFAMILY SSF51351 2 253 4.45E-88 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25855 7cdbed409f70e1a059901f5c5fbb94d6 261 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 244 9.0E-54 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25855 7cdbed409f70e1a059901f5c5fbb94d6 261 Pfam PF00121 Triosephosphate isomerase 6 251 1.7E-85 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25855 7cdbed409f70e1a059901f5c5fbb94d6 261 ProSitePatterns PS00171 Triosephosphate isomerase active site. 170 180 - T 28-03-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25855 7cdbed409f70e1a059901f5c5fbb94d6 261 Gene3D G3DSA:3.20.20.70 1 258 1.8E-97 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS25855 7cdbed409f70e1a059901f5c5fbb94d6 261 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 3 255 38.691 T 28-03-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 Gene3D G3DSA:3.40.710.10 67 320 6.2E-25 T 28-03-2018 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 SUPERFAMILY SSF56601 68 317 5.83E-57 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 Pfam PF13354 Beta-lactamase enzyme family 90 294 5.7E-27 T 28-03-2018 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 PRINTS PR00118 Beta-lactamase class A signature 204 229 1.6E-55 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 PRINTS PR00118 Beta-lactamase class A signature 142 167 1.6E-55 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 PRINTS PR00118 Beta-lactamase class A signature 255 270 1.6E-55 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 PRINTS PR00118 Beta-lactamase class A signature 100 117 1.6E-55 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 PRINTS PR00118 Beta-lactamase class A signature 69 93 1.6E-55 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS11115 9bc57a689a1aa549c11e6f25017a5ba5 325 PRINTS PR00118 Beta-lactamase class A signature 178 202 1.6E-55 T 28-03-2018 IPR000871 Beta-lactamase, class-A GO:0008800|GO:0030655|GO:0046677 KEGG: 00311+3.5.2.6 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00149 Fumarate lyase superfamily signature 110 128 2.1E-26 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00149 Fumarate lyase superfamily signature 283 299 2.1E-26 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00149 Fumarate lyase superfamily signature 155 173 2.1E-26 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00149 Fumarate lyase superfamily signature 239 266 2.1E-26 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 Gene3D G3DSA:1.20.200.10 115 382 1.2E-89 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 SUPERFAMILY SSF48557 13 463 2.36E-134 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 Gene3D G3DSA:1.10.40.30 383 440 2.2E-26 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00145 Argininosuccinate lyase family signature 150 170 2.6E-53 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00145 Argininosuccinate lyase family signature 239 263 2.6E-53 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00145 Argininosuccinate lyase family signature 318 337 2.6E-53 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00145 Argininosuccinate lyase family signature 109 131 2.6E-53 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00145 Argininosuccinate lyase family signature 201 217 2.6E-53 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 PRINTS PR00145 Argininosuccinate lyase family signature 283 299 2.6E-53 T 28-03-2018 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 TIGRFAM TIGR00838 argH: argininosuccinate lyase 10 462 7.3E-179 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 Pfam PF14698 Argininosuccinate lyase C-terminal 371 439 5.7E-23 T 28-03-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 Hamap MF_00006 Argininosuccinate lyase [argH]. 9 461 39.399 T 28-03-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 ProSitePatterns PS00163 Fumarate lyases signature. 283 292 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 Gene3D G3DSA:1.10.275.10 9 114 6.7E-32 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CNX65_RS27150 9bbda154f14cf2a3df8a6be5ed4a42b2 469 Pfam PF00206 Lyase 20 308 3.7E-61 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CNX65_RS13310 f61a0bbdde2a7689e93bad28f7e0d40a 226 Pfam PF00857 Isochorismatase family 19 207 1.2E-36 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS13310 f61a0bbdde2a7689e93bad28f7e0d40a 226 Gene3D G3DSA:3.40.50.850 3 221 1.7E-48 T 28-03-2018 CNX65_RS13310 f61a0bbdde2a7689e93bad28f7e0d40a 226 SUPERFAMILY SSF52499 11 213 7.33E-47 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS22780 4c1d24037ebec0422ffc6659d4032eb2 367 SUPERFAMILY SSF53383 5 357 1.29E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS22780 4c1d24037ebec0422ffc6659d4032eb2 367 PIRSF PIRSF000390 2 361 2.5E-100 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS22780 4c1d24037ebec0422ffc6659d4032eb2 367 Gene3D G3DSA:3.40.640.10 4 232 1.2E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS22780 4c1d24037ebec0422ffc6659d4032eb2 367 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 13 355 1.3E-110 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS22780 4c1d24037ebec0422ffc6659d4032eb2 367 Gene3D G3DSA:3.90.1150.10 233 362 3.9E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 SUPERFAMILY SSF46689 246 295 8.06E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 SMART SM00342 210 293 1.5E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 Gene3D G3DSA:1.10.10.60 249 295 1.5E-13 T 28-03-2018 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 247 289 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 SUPERFAMILY SSF46689 193 244 1.08E-6 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 Pfam PF12833 Helix-turn-helix domain 216 294 2.1E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 Gene3D G3DSA:2.60.120.280 13 178 3.2E-16 T 28-03-2018 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 Pfam PF12852 Cupin 1 177 1.4E-37 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 277 293 1.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 262 277 1.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS16935 7443ed2c04178557ff40b70425e9de96 300 Gene3D G3DSA:1.10.10.60 192 248 5.2E-11 T 28-03-2018 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 PRINTS PR00067 Catalase signature 123 141 8.4E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 PRINTS PR00067 Catalase signature 104 121 8.4E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 PRINTS PR00067 Catalase signature 288 315 8.4E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 PRINTS PR00067 Catalase signature 320 346 8.4E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 PRINTS PR00067 Catalase signature 83 101 8.4E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 PRINTS PR00067 Catalase signature 21 44 8.4E-67 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 SMART SM01060 8 389 2.6E-273 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 Gene3D G3DSA:2.40.180.10 1 357 3.0E-159 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 ProSitePatterns PS00438 Catalase proximal active site signature. 44 60 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 Pfam PF00199 Catalase 8 385 4.7E-181 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 333 341 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 SUPERFAMILY SSF56634 5 481 2.09E-197 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 PIRSF PIRSF038928 1 484 1.6E-227 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS01040 a8967a74a0f55f969f42c905df3d33f6 484 Pfam PF06628 Catalase-related immune-responsive 418 479 9.6E-16 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 218 229 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 Gene3D G3DSA:2.40.10.10 76 138 3.2E-19 T 28-03-2018 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 SMART SM00020 43 263 1.1E-69 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 SUPERFAMILY SSF50494 17 260 5.71E-65 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 Pfam PF00089 Trypsin 44 260 4.5E-53 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 81 86 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 Gene3D G3DSA:2.40.10.10 44 75 8.0E-14 T 28-03-2018 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 Gene3D G3DSA:2.40.10.10 139 269 3.5E-35 T 28-03-2018 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 71 86 1.1E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 127 141 1.1E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS27400 c2b4f35ff9cc4b6afce6a1a63b319cc5 269 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 217 229 1.1E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS19545 73857b1706aafd8e9b45eb6c9c95eb56 521 SUPERFAMILY SSF103378 31 398 4.84E-49 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 CNX65_RS19545 73857b1706aafd8e9b45eb6c9c95eb56 521 Pfam PF03972 MmgE/PrpD family 35 393 9.4E-36 T 28-03-2018 IPR005656 MmgE/PrpD GO:0016829 CNX65_RS19545 73857b1706aafd8e9b45eb6c9c95eb56 521 Gene3D G3DSA:1.10.4100.10 15 317 3.1E-36 T 28-03-2018 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 Pfam PF01238 Phosphomannose isomerase type I 4 363 4.4E-64 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PIRSF PIRSF001480 1 406 2.5E-99 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 245 264 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 82 103 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 32 47 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 283 302 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 127 150 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 229 244 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 4 22 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 PRINTS PR00714 Phosphomannose isomerase type I signature 264 283 9.4E-62 T 28-03-2018 IPR016305 Mannose-6-phosphate isomerase GO:0004476|GO:0009298 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 Gene3D G3DSA:2.60.120.10 5 164 3.7E-46 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 Gene3D G3DSA:1.10.441.10 165 271 9.4E-29 T 28-03-2018 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 SUPERFAMILY SSF51182 3 400 1.28E-98 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 3 396 6.9E-70 T 28-03-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-446205 CNX65_RS31115 2333e4efd4abe217d403029a65691f65 407 Gene3D G3DSA:2.60.120.10 302 406 2.7E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 SUPERFAMILY SSF50370 33 161 1.28E-34 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 Gene3D G3DSA:2.80.10.50 117 162 8.3E-15 T 28-03-2018 CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 Gene3D G3DSA:2.80.10.50 82 116 3.6E-9 T 28-03-2018 CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 Pfam PF00652 Ricin-type beta-trefoil lectin domain 40 159 4.0E-26 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 Gene3D G3DSA:3.30.386.10 178 282 2.9E-50 T 28-03-2018 CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 Gene3D G3DSA:1.20.141.10 283 410 4.1E-57 T 28-03-2018 CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 Gene3D G3DSA:4.10.1090.10 14 81 2.4E-14 T 28-03-2018 CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 Pfam PF01374 Glycosyl hydrolase family 46 194 403 3.4E-101 T 28-03-2018 IPR000400 Glycoside hydrolase, family 46 GO:0005576|GO:0005975|GO:0016977 KEGG: 00520+3.2.1.132 CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 SUPERFAMILY SSF53955 182 414 1.8E-89 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS21690 a9fc7f274a7249bcf6fe931f5f1f4dd2 415 SMART SM00458 33 162 3.0E-27 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF05729 NACHT domain 657 815 3.9E-9 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SUPERFAMILY SSF50494 16 195 3.35E-17 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SUPERFAMILY SSF50978 1153 1467 2.88E-74 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SUPERFAMILY SSF56300 232 294 5.69E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SUPERFAMILY SSF56300 325 448 5.69E-14 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00805 Pentapeptide repeats (8 copies) 1051 1079 0.013 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00805 Pentapeptide repeats (8 copies) 1084 1114 1.7E-5 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.40.10.10 109 200 8.2E-6 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:3.60.21.10 211 504 7.4E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.140.10.30 1134 1224 4.2E-18 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SUPERFAMILY SSF141571 1052 1124 4.84E-15 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.160.20.80 1035 1133 2.6E-16 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.40.10.10 12 108 9.6E-6 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SUPERFAMILY SSF52540 649 823 3.63E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.80.10.50 1389 1478 1.4E-23 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.40.50.140 1479 1501 4.4E-7 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.40.50.140 1316 1340 1.0E-10 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:3.40.50.300 605 922 3.6E-6 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.130.10.150 1643 1751 2.3E-21 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SUPERFAMILY SSF50978 1440 1717 2.61E-74 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1536 1550 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00149 Calcineurin-like phosphoesterase 232 404 4.8E-5 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:1.10.10.670 1341 1388 2.8E-9 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1442 1466 0.016 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1308 1343 4.0E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1225 1261 2.7E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1513 1549 6.5E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1356 1384 0.12 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1389 1426 3.6E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1556 1590 1.2E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1679 1712 1.3E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1636 1678 0.032 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1594 1630 1.4E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1473 1507 0.0021 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1265 1302 0.0041 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Pfam PF00400 WD domain, G-beta repeat 1188 1220 1.3E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.40.10.120 1561 1584 2.0E-13 T 28-03-2018 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1551 1590 1.9E-11 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1428 1467 8.9E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1305 1344 1.5E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1346 1385 7.1E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1469 1508 2.9E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1674 1713 3.5E-10 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1633 1672 0.0072 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1592 1631 1.2E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1387 1426 3.1E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1223 1262 1.3E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1140 1179 240.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1264 1303 1.5E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1510 1549 7.5E-11 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 SMART SM00320 1182 1221 1.5E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.130.10.10 1225 1315 1.3E-29 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.130.10.10 1502 1560 2.8E-21 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS31555 f8f6c48e8863033a3565040289da2d3a 1784 Gene3D G3DSA:2.130.10.10 1585 1642 1.5E-22 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS29945 0276c5dfc7c89e016fdb8893db370d8f 312 Pfam PF00005 ABC transporter 25 165 3.2E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS29945 0276c5dfc7c89e016fdb8893db370d8f 312 Gene3D G3DSA:3.40.50.300 6 253 1.4E-50 T 28-03-2018 CNX65_RS29945 0276c5dfc7c89e016fdb8893db370d8f 312 SUPERFAMILY SSF52540 11 226 7.46E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29945 0276c5dfc7c89e016fdb8893db370d8f 312 SMART SM00382 34 212 2.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 SMART SM00823 Phosphopantetheine attachment site 990 1059 2.6E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Pfam PF00550 Phosphopantetheine attachment site 992 1055 1.1E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 SUPERFAMILY SSF51735 1102 1380 2.46E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Pfam PF00501 AMP-binding enzyme 485 882 1.4E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 SUPERFAMILY SSF52777 34 201 5.78E-36 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Gene3D G3DSA:3.40.50.980 475 629 1.0E-44 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Gene3D G3DSA:1.10.1200.10 996 1062 1.8E-20 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Pfam PF07993 Male sterility protein 1106 1341 1.4E-61 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 SUPERFAMILY SSF47336 983 1055 8.9E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Gene3D G3DSA:3.30.559.10 23 228 2.2E-31 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 PIRSF PIRSF001617 925 1478 3.5E-80 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 PIRSF PIRSF001617 209 593 1.3E-16 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 PIRSF PIRSF001617 601 936 7.1E-27 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 505 906 6.7E-134 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1014 1029 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Gene3D G3DSA:3.30.300.30 877 995 8.4E-35 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Gene3D G3DSA:3.40.50.720 1094 1425 8.3E-39 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 ProSitePatterns PS00455 Putative AMP-binding domain signature. 624 635 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 SUPERFAMILY SSF56801 444 1003 9.94E-153 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1103 1466 1.8E-98 T 28-03-2018 IPR010080 Thioester reductase-like domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Gene3D G3DSA:3.40.50.980 630 788 3.8E-35 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Pfam PF13193 AMP-binding enzyme C-terminal domain 890 965 5.8E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Pfam PF00668 Condensation domain 34 461 9.0E-71 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 Gene3D G3DSA:2.30.38.10 790 872 7.8E-26 T 28-03-2018 CNX65_RS18320 945d008d4c4be1e7a813db1380b82f1e 1482 SUPERFAMILY SSF52777 210 470 4.56E-52 T 28-03-2018 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 Gene3D G3DSA:1.10.10.10 137 218 5.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 173 200 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 173 189 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 159 173 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 189 201 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 SUPERFAMILY SSF52172 3 187 6.94E-31 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 SMART SM00448 3 118 3.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 158 213 2.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 SMART SM00421 156 213 4.3E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 Pfam PF00072 Response regulator receiver domain 5 119 5.4E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS15130 384c156a71643d1a0b5b7de80f0ba11c 223 Gene3D G3DSA:3.40.50.2300 2 136 3.3E-34 T 28-03-2018 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 SMART SM00421 153 210 1.1E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 2.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 2.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 2.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 SMART SM00448 7 120 1.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 Gene3D G3DSA:1.10.10.10 132 218 1.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 SUPERFAMILY SSF52172 6 135 2.7E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 156 209 1.3E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 Pfam PF00072 Response regulator receiver domain 9 120 2.8E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 Gene3D G3DSA:3.40.50.2300 6 131 2.5E-36 T 28-03-2018 CNX65_RS26765 b9c4c86613387c70222824926a63d786 218 SUPERFAMILY SSF46894 140 215 4.76E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS06515 6f5241889b524d867119c9b0bac0f857 564 SUPERFAMILY SSF52540 318 554 1.01E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06515 6f5241889b524d867119c9b0bac0f857 564 Pfam PF00005 ABC transporter 341 489 2.6E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS06515 6f5241889b524d867119c9b0bac0f857 564 Gene3D G3DSA:3.40.50.300 320 559 4.4E-47 T 28-03-2018 CNX65_RS06515 6f5241889b524d867119c9b0bac0f857 564 SMART SM00382 349 533 4.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS06515 6f5241889b524d867119c9b0bac0f857 564 Gene3D G3DSA:1.20.1560.10 1 307 2.9E-18 T 28-03-2018 CNX65_RS06515 6f5241889b524d867119c9b0bac0f857 564 SUPERFAMILY SSF90123 5 303 8.63E-23 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 Gene3D G3DSA:3.30.565.10 291 434 1.5E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 SUPERFAMILY SSF55874 274 430 3.54E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 SUPERFAMILY SSF47384 202 283 2.94E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 Pfam PF00512 His Kinase A (phospho-acceptor) domain 220 283 6.5E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 SMART SM00387 323 432 1.3E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 358 372 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 386 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 393 411 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 PRINTS PR00344 Bacterial sensor protein C-terminal signature 416 429 5.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 327 416 4.9E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 SMART SM00304 165 218 3.2E-8 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 SMART SM00388 219 284 4.0E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS27240 2e1f735fce3f294efde0527977dd8911 434 Gene3D G3DSA:1.10.287.130 209 280 1.6E-7 T 28-03-2018 CNX65_RS03775 13f588cc73618c11445bcc6a332c3d7c 349 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 319 1.3E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS03775 13f588cc73618c11445bcc6a332c3d7c 349 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 340 1.9E-27 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS03775 13f588cc73618c11445bcc6a332c3d7c 349 Pfam PF00005 ABC transporter 48 200 7.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03775 13f588cc73618c11445bcc6a332c3d7c 349 SUPERFAMILY SSF52540 19 272 7.24E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03775 13f588cc73618c11445bcc6a332c3d7c 349 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03775 13f588cc73618c11445bcc6a332c3d7c 349 Gene3D G3DSA:3.40.50.300 16 346 4.6E-84 T 28-03-2018 CNX65_RS03775 13f588cc73618c11445bcc6a332c3d7c 349 SMART SM00382 56 250 2.3E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Gene3D G3DSA:1.25.40.10 823 962 3.2E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Pfam PF03704 Bacterial transcriptional activator domain 108 251 1.2E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Pfam PF13191 AAA ATPase domain 450 603 2.7E-17 T 28-03-2018 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Pfam PF00486 Transcriptional regulatory protein, C terminal 30 101 3.9E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Gene3D G3DSA:1.25.40.10 110 266 3.0E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Gene3D G3DSA:3.40.50.300 441 609 7.9E-10 T 28-03-2018 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Gene3D G3DSA:1.10.10.10 10 109 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 SUPERFAMILY SSF52540 438 678 3.96E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 SMART SM01043 108 251 7.8E-54 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 SUPERFAMILY SSF46894 8 101 4.82E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 SUPERFAMILY SSF48452 104 254 1.64E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 Gene3D G3DSA:1.25.40.10 978 1258 2.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14880 146efb1e1799748eceb1427be853d59b 1266 SMART SM00862 21 101 3.7E-8 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS03920 6f1d186dbb5b20256104a2bc893e6c63 387 TIGRFAM TIGR02149 glgA_Coryne: glycogen synthase, Corynebacterium family 2 381 8.4E-178 T 28-03-2018 IPR011875 Alpha-maltose-1-phosphate synthase GO:0009250|GO:0016740 CNX65_RS03920 6f1d186dbb5b20256104a2bc893e6c63 387 Gene3D G3DSA:3.40.50.2000 2 172 5.3E-19 T 28-03-2018 CNX65_RS03920 6f1d186dbb5b20256104a2bc893e6c63 387 Gene3D G3DSA:3.40.50.2000 173 367 1.3E-49 T 28-03-2018 CNX65_RS03920 6f1d186dbb5b20256104a2bc893e6c63 387 SUPERFAMILY SSF53756 8 384 1.36E-84 T 28-03-2018 CNX65_RS03920 6f1d186dbb5b20256104a2bc893e6c63 387 Pfam PF00534 Glycosyl transferases group 1 190 361 1.5E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS03920 6f1d186dbb5b20256104a2bc893e6c63 387 Pfam PF13439 Glycosyltransferase Family 4 15 177 2.3E-29 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS00885 3cbbbcc6ca9987120170463310a6946a 135 Gene3D G3DSA:3.30.1330.40 7 135 8.7E-27 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS00885 3cbbbcc6ca9987120170463310a6946a 135 SUPERFAMILY SSF55298 4 134 1.1E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS00885 3cbbbcc6ca9987120170463310a6946a 135 Pfam PF01042 Endoribonuclease L-PSP 26 134 2.5E-18 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CNX65_RS00230 df7a440fa5fc63ee01ffa5769c4f0f78 249 Pfam PF07987 Domain of unkown function (DUF1775) 35 182 6.7E-47 T 28-03-2018 IPR012533 YcnI-like CNX65_RS23785 ebff3ae15085cc8f0af023295a2ab508 189 Pfam PF16859 Bacterial transcriptional repressor C-terminal 77 181 1.9E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS23785 ebff3ae15085cc8f0af023295a2ab508 189 SUPERFAMILY SSF46689 11 71 6.16E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23785 ebff3ae15085cc8f0af023295a2ab508 189 Gene3D G3DSA:1.10.10.60 2 62 1.3E-11 T 28-03-2018 CNX65_RS23785 ebff3ae15085cc8f0af023295a2ab508 189 SUPERFAMILY SSF48498 79 186 5.34E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS23785 ebff3ae15085cc8f0af023295a2ab508 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 64 4.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23785 ebff3ae15085cc8f0af023295a2ab508 189 Gene3D G3DSA:1.10.357.10 63 189 3.0E-14 T 28-03-2018 CNX65_RS33845 9f57286bb21e34d9ec4463fef0b6817a 292 TIGRFAM TIGR04378 myo_inos_iolB: 5-deoxy-glucuronate isomerase 20 270 5.0E-77 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CNX65_RS33845 9f57286bb21e34d9ec4463fef0b6817a 292 Gene3D G3DSA:2.60.120.10 18 120 1.5E-34 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS33845 9f57286bb21e34d9ec4463fef0b6817a 292 Pfam PF04962 KduI/IolB family 18 269 2.9E-75 T 28-03-2018 IPR021120 KduI/IolB isomerase GO:0016861 KEGG: 00040+5.3.1.17|MetaCyc: PWY-6507 CNX65_RS33845 9f57286bb21e34d9ec4463fef0b6817a 292 SUPERFAMILY SSF51182 18 253 5.13E-51 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS33845 9f57286bb21e34d9ec4463fef0b6817a 292 Gene3D G3DSA:2.60.120.10 121 274 1.3E-54 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS33845 9f57286bb21e34d9ec4463fef0b6817a 292 PIRSF PIRSF036628 3 275 4.9E-74 T 28-03-2018 IPR024203 5-deoxy-glucuronate isomerase, IolB GO:0008880|GO:0019310 KEGG: 00562+5.3.1.30 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 Gene3D G3DSA:3.40.50.300 67 244 1.0E-6 T 28-03-2018 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 Gene3D G3DSA:1.25.40.10 275 554 0.018 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 Pfam PF00196 Bacterial regulatory proteins, luxR family 936 984 5.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 Gene3D G3DSA:1.25.40.10 739 942 1.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 SUPERFAMILY SSF52540 95 244 3.74E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 SUPERFAMILY SSF48452 606 701 4.64E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 SUPERFAMILY SSF46894 932 987 7.48E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 ProSitePatterns PS00622 LuxR-type HTH domain signature. 951 978 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 Gene3D G3DSA:1.10.10.10 943 991 7.3E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 Gene3D G3DSA:1.25.40.10 596 722 2.2E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 Pfam PF13191 AAA ATPase domain 76 239 4.5E-17 T 28-03-2018 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 937 951 1.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 967 979 1.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 951 967 1.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13765 324d3b01eb8a5fc2e76c56c910ef7411 1004 SMART SM00421 934 991 1.3E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS33075 abe1fc0047e2d626f3104c86bb5154ec 317 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 87 314 2.7E-71 T 28-03-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 CNX65_RS33075 abe1fc0047e2d626f3104c86bb5154ec 317 Pfam PF01578 Cytochrome C assembly protein 110 311 2.2E-47 T 28-03-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 SUPERFAMILY SSF49785 830 937 1.87E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 Pfam PF00082 Subtilase family 281 644 2.2E-16 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 Gene3D G3DSA:2.60.120.260 778 938 6.6E-20 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 Pfam PF01483 Proprotein convertase P-domain 831 933 1.9E-8 T 28-03-2018 IPR002884 Proprotein convertase, P GO:0004252|GO:0006508 CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 Gene3D G3DSA:2.60.40.10 673 770 7.6E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 Gene3D G3DSA:3.40.50.200 213 665 4.6E-35 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 594 604 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 SUPERFAMILY SSF52743 546 656 5.24E-32 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 SUPERFAMILY SSF52743 493 515 5.24E-32 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS25550 be029dab0813a302fbbe2853daeea610 938 SUPERFAMILY SSF52743 219 358 5.24E-32 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 Gene3D G3DSA:3.40.50.1260 1 166 2.0E-53 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 SUPERFAMILY SSF53748 11 388 1.65E-139 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 Gene3D G3DSA:3.40.50.1260 172 376 1.9E-84 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PIRSF PIRSF000724 1 389 1.3E-128 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 Pfam PF00162 Phosphoglycerate kinase 12 378 7.1E-139 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 16 26 - T 28-03-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 340 351 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 307 332 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 11 27 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 162 184 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 32 54 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 364 381 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 132 154 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 185 204 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 PRINTS PR00477 Phosphoglycerate kinase family signature 100 115 7.5E-80 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25860 b0b5a0f99c90ca4290513024fa5644f1 389 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 6 388 39.718 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25825 82345e00c7789e6177fbcdf01a96a988 450 SUPERFAMILY SSF55874 315 423 1.18E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25825 82345e00c7789e6177fbcdf01a96a988 450 Gene3D G3DSA:3.30.565.10 275 426 2.4E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25825 82345e00c7789e6177fbcdf01a96a988 450 Pfam PF07730 Histidine kinase 234 298 2.4E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 Pfam PF01019 Gamma-glutamyltranspeptidase 28 586 4.9E-113 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 123 142 2.6E-26 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 105 123 2.6E-26 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 404 422 2.6E-26 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 458 473 2.6E-26 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 35 60 2.6E-26 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 SUPERFAMILY SSF56235 399 592 8.49E-133 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS00260 fc961f85757018865fca14d3b59a4c9d 593 SUPERFAMILY SSF56235 2 362 8.49E-133 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 Gene3D G3DSA:3.40.50.2300 74 180 7.5E-23 T 28-03-2018 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 SUPERFAMILY SSF53822 75 346 5.44E-76 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 Gene3D G3DSA:3.40.50.2300 181 346 5.8E-55 T 28-03-2018 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 20 38 - T 28-03-2018 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 Gene3D G3DSA:1.10.10.60 13 32 0.0021 T 28-03-2018 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 Pfam PF13377 Periplasmic binding protein-like domain 182 343 4.7E-40 T 28-03-2018 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 SMART SM00354 17 84 1.7E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 SUPERFAMILY SSF47413 17 65 8.44E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 62 1.7E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09100 2af7143208bf3ae020e459679cee3377 347 Gene3D G3DSA:1.10.260.40 33 73 6.0E-18 T 28-03-2018 CNX65_RS34470 fc38c67ba858adbbc5801aa38c78ddf3 268 Pfam PF01575 MaoC like domain 173 230 1.2E-11 T 28-03-2018 IPR002539 MaoC-like domain CNX65_RS34470 fc38c67ba858adbbc5801aa38c78ddf3 268 Gene3D G3DSA:3.10.129.10 17 155 1.1E-24 T 28-03-2018 CNX65_RS34470 fc38c67ba858adbbc5801aa38c78ddf3 268 SUPERFAMILY SSF54637 30 153 1.66E-10 T 28-03-2018 IPR029069 HotDog domain CNX65_RS34470 fc38c67ba858adbbc5801aa38c78ddf3 268 Gene3D G3DSA:3.10.129.10 158 267 3.3E-16 T 28-03-2018 CNX65_RS34470 fc38c67ba858adbbc5801aa38c78ddf3 268 SUPERFAMILY SSF54637 163 265 4.53E-20 T 28-03-2018 IPR029069 HotDog domain CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 Gene3D G3DSA:1.10.10.10 93 143 8.8E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 PRINTS PR00046 Major sigma-70 factor signature 199 211 8.5E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 PRINTS PR00046 Major sigma-70 factor signature 216 231 8.5E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 PRINTS PR00046 Major sigma-70 factor signature 231 242 8.5E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 PRINTS PR00046 Major sigma-70 factor signature 47 60 8.5E-13 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 20 246 9.2E-81 T 28-03-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 17 245 1.7E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 Pfam PF04545 Sigma-70, region 4 195 243 8.9E-17 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 Gene3D G3DSA:1.10.10.10 168 252 6.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 SUPERFAMILY SSF88659 163 248 1.21E-21 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 PIRSF PIRSF000770 1 252 7.8E-57 T 28-03-2018 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 47 60 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 SUPERFAMILY SSF88659 93 157 4.36E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 Pfam PF04542 Sigma-70 region 2 20 92 7.9E-18 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 Gene3D G3DSA:1.10.1740.10 5 90 4.2E-21 T 28-03-2018 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 216 242 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29015 963c9ea5ea7ff5e66cb0e99365bf8cdb 252 SUPERFAMILY SSF88946 3 92 5.49E-27 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 SUPERFAMILY SSF51971 110 289 2.82E-38 T 28-03-2018 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 SUPERFAMILY SSF51971 12 65 2.82E-38 T 28-03-2018 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 SUPERFAMILY SSF51971 348 405 2.82E-38 T 28-03-2018 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 Gene3D G3DSA:3.30.9.10 235 353 1.1E-15 T 28-03-2018 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 Pfam PF01266 FAD dependent oxidoreductase 13 400 1.0E-54 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 Gene3D G3DSA:3.50.50.60 7 234 7.6E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 SUPERFAMILY SSF54373 276 363 1.57E-8 T 28-03-2018 CNX65_RS18195 3d51091bc53d4b5d8525ea94a7f12d21 418 Gene3D G3DSA:3.50.50.60 354 418 7.7E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS25020 6b76203d8d7ea320fe450a824d24e55e 330 Pfam PF01183 Glycosyl hydrolases family 25 5 164 2.4E-21 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CNX65_RS25020 6b76203d8d7ea320fe450a824d24e55e 330 SMART SM00641 2 104 3.8E-10 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CNX65_RS25020 6b76203d8d7ea320fe450a824d24e55e 330 Gene3D G3DSA:3.20.20.80 1 209 3.4E-41 T 28-03-2018 CNX65_RS25020 6b76203d8d7ea320fe450a824d24e55e 330 SUPERFAMILY SSF51445 2 204 7.72E-35 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS05275 2ec16df7d5663abdd4c0bd8d1ed9bb41 127 TIGRFAM TIGR00632 vsr: DNA mismatch endonuclease Vsr 1 107 2.6E-32 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CNX65_RS05275 2ec16df7d5663abdd4c0bd8d1ed9bb41 127 Pfam PF03852 DNA mismatch endonuclease Vsr 1 60 1.3E-17 T 28-03-2018 IPR004603 DNA mismatch endonuclease vsr GO:0004519|GO:0006298 CNX65_RS05275 2ec16df7d5663abdd4c0bd8d1ed9bb41 127 Gene3D G3DSA:3.40.960.10 8 123 1.9E-24 T 28-03-2018 CNX65_RS05275 2ec16df7d5663abdd4c0bd8d1ed9bb41 127 SUPERFAMILY SSF52980 1 118 3.75E-33 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Gene3D G3DSA:1.10.150.20 576 639 1.5E-16 T 28-03-2018 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 SMART SM00465 17 99 1.1E-21 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Pfam PF14520 Helix-hairpin-helix domain 587 638 2.4E-8 T 28-03-2018 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 401 572 2.4E-47 T 28-03-2018 IPR001162 UvrC family homology region CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Gene3D G3DSA:3.40.1440.10 5 102 9.4E-23 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 SUPERFAMILY SSF47781 532 639 3.5E-24 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 13 619 1.3E-148 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 SMART SM00278 586 605 9.2 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 SMART SM00278 618 637 0.48 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Pfam PF02151 UvrB/uvrC motif 210 242 5.8E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 SUPERFAMILY SSF46600 195 247 6.93E-14 T 28-03-2018 IPR001943 UVR domain GO:0005515 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 SUPERFAMILY SSF82771 17 101 2.62E-22 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Hamap MF_00203 UvrABC system protein C [uvrC]. 4 637 29.987 T 28-03-2018 IPR004791 UvrABC system, subunit C GO:0005737|GO:0006281|GO:0009380|GO:0009381 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Gene3D G3DSA:4.10.860.10 187 247 7.6E-15 T 28-03-2018 IPR001943 UVR domain GO:0005515 CNX65_RS25895 0399a6df069f651174e8707b1ac1ae08 649 Pfam PF01541 GIY-YIG catalytic domain 19 92 7.8E-10 T 28-03-2018 IPR000305 GIY-YIG nuclease superfamily CNX65_RS32080 01490503a3cfd002c4396bc1f6c475a3 190 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 184 6.7E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS32080 01490503a3cfd002c4396bc1f6c475a3 190 Gene3D G3DSA:1.10.10.10 118 190 3.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32080 01490503a3cfd002c4396bc1f6c475a3 190 SUPERFAMILY SSF88946 12 116 4.24E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS32080 01490503a3cfd002c4396bc1f6c475a3 190 Pfam PF08281 Sigma-70, region 4 130 180 3.4E-11 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS32080 01490503a3cfd002c4396bc1f6c475a3 190 Pfam PF04542 Sigma-70 region 2 27 98 1.2E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS32080 01490503a3cfd002c4396bc1f6c475a3 190 SUPERFAMILY SSF88659 112 185 9.91E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS32080 01490503a3cfd002c4396bc1f6c475a3 190 Gene3D G3DSA:1.10.1740.10 9 117 5.6E-21 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF47336 3486 3594 8.24E-24 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 1501 1713 6.71E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 4310 4404 1.39E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 4119 4248 1.39E-64 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 2595 2695 4.45E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 2404 2533 4.45E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00698 Acyl transferase domain 668 989 1.7E-48 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00698 Acyl transferase domain 4121 4437 9.5E-81 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00698 Acyl transferase domain 2406 2722 8.3E-77 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00698 Acyl transferase domain 5833 6114 1.8E-60 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 4760 4924 3.35E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:1.10.1200.10 3484 3579 8.7E-21 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:1.10.1200.10 1775 1872 2.1E-19 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 6013 6136 1.9E-26 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 5468 5484 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 2037 2053 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 120 390 1.0E-86 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 5297 5567 7.5E-82 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 3580 3842 2.7E-83 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 1873 2136 3.1E-87 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00550 Phosphopantetheine attachment site 3490 3556 4.6E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00550 Phosphopantetheine attachment site 6936 7002 9.8E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00550 Phosphopantetheine attachment site 1783 1849 2.9E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00550 Phosphopantetheine attachment site 37 102 5.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00550 Phosphopantetheine attachment site 5214 5280 1.1E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF08659 KR domain 1501 1674 9.0E-57 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF08659 KR domain 3214 3385 2.3E-54 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF08659 KR domain 4936 5107 1.4E-52 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF08659 KR domain 6653 6827 1.7E-53 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 2408 2703 5.0E-111 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 4123 4418 2.2E-114 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 669 971 4.2E-112 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5833 6129 3.7E-120 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.50.720 6651 6891 5.1E-48 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.50.720 3207 3449 4.4E-47 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.50.720 1497 1737 7.2E-49 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.50.720 4928 5181 2.3E-50 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF47336 5207 5319 8.11E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 5305 5555 9.0E-86 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1874 2124 1.0E-90 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 3580 3830 2.1E-85 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 128 378 3.4E-88 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.30.70.250 5967 6012 1.5E-18 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.30.70.250 2546 2588 5.7E-13 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.30.70.250 810 851 5.7E-17 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.30.70.250 4260 4299 8.4E-18 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM01294 5213 5280 1.4E-4 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM01294 41 106 7.8E-4 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM01294 3489 3556 2.7E-5 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM01294 6934 7002 2.4E-4 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM01294 1782 1849 3.4E-5 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 3515 3530 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:1.10.1200.10 1 108 1.3E-17 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 5830 5957 2.3E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 6021 6118 2.3E-70 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 852 976 2.3E-27 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 1325 1488 6.69E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.10.129.10 6192 6317 1.8E-9 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.10.129.10 2773 2898 5.6E-6 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.10.129.10 4490 4612 1.0E-7 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.10.129.10 1036 1166 8.5E-10 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00825 Beta-ketoacyl synthase 1876 2300 1.3E-226 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00825 Beta-ketoacyl synthase 5307 5731 8.0E-214 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00825 Beta-ketoacyl synthase 3582 4006 2.4E-217 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00825 Beta-ketoacyl synthase 130 554 2.3E-219 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF53901 125 491 1.65E-103 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF55048 4247 4309 9.55E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 3209 3456 6.67E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1808 1823 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF55048 5956 6020 3.27E-12 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 6468 6643 6.8E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF47336 35 142 1.31E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 4931 5170 3.4E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 3743 3759 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF14765 Polyketide synthase dehydratase 6190 6463 3.1E-55 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF14765 Polyketide synthase dehydratase 1038 1318 5.0E-54 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF14765 Polyketide synthase dehydratase 4488 4753 4.0E-52 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF14765 Polyketide synthase dehydratase 2771 3042 4.2E-47 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 6961 6976 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF53901 1870 2246 2.13E-104 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF53901 5301 5675 1.3E-99 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00826 6190 6357 3.6E-79 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00826 1038 1201 2.7E-85 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00826 4488 4649 1.6E-79 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00826 2771 2932 2.7E-81 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF55048 2533 2593 7.46E-8 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF47336 1779 1889 3.4E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF55048 796 860 2.22E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 2589 2705 1.6E-24 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 4300 4420 4.1E-24 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 2404 2545 5.3E-43 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 665 809 4.0E-41 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 4119 4259 4.5E-40 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.366.10 5829 5966 9.4E-44 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 2139 2298 2.5E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 393 552 1.3E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 3845 4004 3.2E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:3.40.47.10 5570 5729 6.0E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:1.10.1200.10 6913 7007 8.7E-21 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 ProSitePatterns PS00012 Phosphopantetheine attachment site. 5239 5254 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 6649 6897 3.97E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 666 797 2.51E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF52151 861 957 2.51E-67 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF47336 6925 7014 2.09E-21 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6653 6829 1.0E-48 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4935 5109 4.9E-49 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1501 1677 7.0E-53 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3213 3387 5.5E-50 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 5684 5797 3.0E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 504 630 1.9E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 3959 4086 3.5E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2252 2350 1.2E-13 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF51735 3048 3200 4.33E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Gene3D G3DSA:1.10.1200.10 5194 5291 5.9E-20 T 28-03-2018 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00823 Phosphopantetheine attachment site 3488 3560 9.9E-33 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00823 Phosphopantetheine attachment site 6934 7006 2.8E-27 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00823 Phosphopantetheine attachment site 1781 1853 1.5E-31 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00823 Phosphopantetheine attachment site 5212 5284 6.6E-32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SMART SM00823 Phosphopantetheine attachment site 35 107 2.5E-21 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 SUPERFAMILY SSF53901 3576 3951 1.31E-101 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 2132 2247 3.6E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 3838 3953 2.8E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 386 501 1.1E-43 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS13645 7cfcf5cfe82557649e70f232da01d934 7085 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 5563 5678 1.3E-42 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Gene3D G3DSA:1.10.10.10 364 435 3.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 226 239 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 198 423 1.4E-35 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 PRINTS PR00046 Major sigma-70 factor signature 226 239 2.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 PRINTS PR00046 Major sigma-70 factor signature 410 421 2.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 PRINTS PR00046 Major sigma-70 factor signature 374 386 2.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 PRINTS PR00046 Major sigma-70 factor signature 250 258 2.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 PRINTS PR00046 Major sigma-70 factor signature 395 410 2.0E-29 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Pfam PF04545 Sigma-70, region 4 370 423 1.3E-18 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Pfam PF04539 Sigma-70 region 3 281 356 1.4E-28 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Pfam PF00140 Sigma-70 factor, region 1.2 133 166 3.7E-16 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Pfam PF04542 Sigma-70 region 2 202 271 1.5E-22 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 12 435 33.185 T 28-03-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 SUPERFAMILY SSF88946 130 272 1.05E-54 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 SUPERFAMILY SSF88659 275 348 1.55E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Gene3D G3DSA:1.10.601.10 1 271 3.5E-78 T 28-03-2018 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 395 421 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 198 434 8.5E-114 T 28-03-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 SUPERFAMILY SSF88659 334 434 2.51E-26 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07475 20071abd8c335d3bd15bf490831831ad 435 Gene3D G3DSA:1.10.10.10 272 322 1.0E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24495 11c88f246900c39477bc426bbd7cb043 327 SUPERFAMILY SSF47323 190 309 1.18E-21 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS24495 11c88f246900c39477bc426bbd7cb043 327 Gene3D G3DSA:1.10.730.10 181 315 1.3E-21 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS19255 7327e181a4d1aef3be486d02f392f7f3 151 Gene3D G3DSA:3.10.180.10 1 151 6.5E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS19255 7327e181a4d1aef3be486d02f392f7f3 151 SUPERFAMILY SSF54593 6 151 2.26E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 SMART SM00448 2 115 1.2E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 Gene3D G3DSA:3.40.50.2300 1 133 2.1E-34 T 28-03-2018 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 208 1.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 Pfam PF00072 Response regulator receiver domain 4 116 8.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 SUPERFAMILY SSF52172 2 131 6.83E-30 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 Gene3D G3DSA:1.10.10.10 134 213 4.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 SUPERFAMILY SSF46894 139 214 1.16E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02985 e8b0b9f596647f56b94769ed78231d58 215 SMART SM00421 151 208 2.2E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1241 1276 4.8E-7 T 28-03-2018 IPR006530 YD repeat CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1287 1313 4.3E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 SUPERFAMILY SSF51294 2003 2146 1.77E-22 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 2120 2146 2.6E-4 T 28-03-2018 IPR030934 Intein C-terminal splicing region CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 Gene3D G3DSA:2.170.16.10 1978 2145 3.2E-35 T 28-03-2018 CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 Pfam PF07591 Pretoxin HINT domain 2013 2145 2.0E-15 T 28-03-2018 CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1737 1815 1.1E-15 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 SMART SM00306 2001 2103 4.9E-10 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS24070 75fe598d2b20926a21ea733ad0ffb20a 2276 Pfam PF05593 RHS Repeat 1241 1276 4.4E-8 T 28-03-2018 IPR031325 RHS repeat CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 SUPERFAMILY SSF55920 2 253 5.1E-70 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 Gene3D G3DSA:3.90.230.10 1 255 1.1E-65 T 28-03-2018 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 73 86 1.4E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 95 111 1.4E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 208 1.4E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 PRINTS PR00599 Methionine aminopeptidase-1 signature 165 177 1.4E-17 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 Pfam PF00557 Metallopeptidase family M24 13 245 1.7E-42 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 Hamap MF_01974 Methionine aminopeptidase [map]. 2 254 32.343 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS20930 c92961a45661d28d10ba063e20f604df 259 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 253 2.2E-72 T 28-03-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 Gene3D G3DSA:2.60.420.10 678 749 1.4E-21 T 28-03-2018 CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 PIRSF PIRSF036289 2 758 2.8E-218 T 28-03-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 323 690 1.8E-135 T 28-03-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 SUPERFAMILY SSF74650 4 268 5.65E-62 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 696 745 1.9E-12 T 28-03-2018 IPR005194 Glycoside hydrolase family 65, C-terminal CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 SUPERFAMILY SSF48208 275 743 7.48E-125 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 Gene3D G3DSA:1.50.10.10 317 677 7.1E-108 T 28-03-2018 CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 14 266 1.6E-64 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CNX65_RS09030 adb186447f7f891ad4d4cac3af4091c0 784 Gene3D G3DSA:2.70.98.40 2 270 8.2E-81 T 28-03-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 4 141 1.5E-46 T 28-03-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 Gene3D G3DSA:3.40.50.1370 142 306 1.4E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 4 306 2.4E-111 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 3 307 74.817 T 28-03-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 SUPERFAMILY SSF53671 2 308 9.17E-98 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 47 54 - T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 Gene3D G3DSA:3.40.50.1370 1 141 9.9E-51 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 259 268 4.6E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 271 294 4.6E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 129 140 4.6E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 47 66 4.6E-26 T 28-03-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 149 304 3.9E-51 T 28-03-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 285 296 1.0E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 45 59 1.0E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 78 91 1.0E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 222 232 1.0E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS27165 7a5bb3df909fec9c81546e9e2b53a2ae 310 PRINTS PR00102 Ornithine carbamoyltransferase signature 118 132 1.0E-29 T 28-03-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS22755 bf396bd2cb33b0569dc09be900f37a0a 341 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 256 1.8E-49 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS22755 bf396bd2cb33b0569dc09be900f37a0a 341 SUPERFAMILY SSF51735 8 327 1.68E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22755 bf396bd2cb33b0569dc09be900f37a0a 341 Gene3D G3DSA:3.40.50.720 2 190 6.4E-35 T 28-03-2018 CNX65_RS22755 bf396bd2cb33b0569dc09be900f37a0a 341 Gene3D G3DSA:3.90.25.10 191 332 4.2E-32 T 28-03-2018 CNX65_RS24805 0c13026baaaeeded0fd9816362bad554 369 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 269 335 3.0E-5 T 28-03-2018 CNX65_RS24805 0c13026baaaeeded0fd9816362bad554 369 Pfam PF03601 Conserved hypothetical protein 698 59 348 8.9E-50 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CNX65_RS08105 7b4806700a0a043dfac94c9ab82fe8bb 501 Gene3D G3DSA:1.10.3810.10 71 272 2.0E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS08105 7b4806700a0a043dfac94c9ab82fe8bb 501 Pfam PF00912 Transglycosylase 80 256 3.1E-51 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS08105 7b4806700a0a043dfac94c9ab82fe8bb 501 SUPERFAMILY SSF53955 68 275 3.09E-56 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS08105 7b4806700a0a043dfac94c9ab82fe8bb 501 Gene3D G3DSA:3.40.710.10 427 489 0.086 T 28-03-2018 CNX65_RS08105 7b4806700a0a043dfac94c9ab82fe8bb 501 Gene3D G3DSA:3.40.710.10 273 393 2.1E-10 T 28-03-2018 CNX65_RS08105 7b4806700a0a043dfac94c9ab82fe8bb 501 SUPERFAMILY SSF56601 243 260 4.5E-9 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS08105 7b4806700a0a043dfac94c9ab82fe8bb 501 SUPERFAMILY SSF56601 288 393 4.5E-9 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS21500 2a2e12e074c513b92d7b2562bf4394d7 275 Gene3D G3DSA:3.40.50.300 3 244 6.3E-60 T 28-03-2018 CNX65_RS21500 2a2e12e074c513b92d7b2562bf4394d7 275 Pfam PF00005 ABC transporter 24 170 5.6E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS21500 2a2e12e074c513b92d7b2562bf4394d7 275 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS21500 2a2e12e074c513b92d7b2562bf4394d7 275 SMART SM00382 31 220 4.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS21500 2a2e12e074c513b92d7b2562bf4394d7 275 SUPERFAMILY SSF52540 5 240 4.02E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 Hamap MF_00456 Glutamate 5-kinase [proB]. 12 263 35.108 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 PRINTS PR00474 Glutamate 5-kinase family signature 155 182 6.8E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 PRINTS PR00474 Glutamate 5-kinase family signature 123 144 6.8E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 PRINTS PR00474 Glutamate 5-kinase family signature 216 236 6.8E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 PRINTS PR00474 Glutamate 5-kinase family signature 83 111 6.8E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 PRINTS PR00474 Glutamate 5-kinase family signature 49 63 6.8E-53 T 28-03-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 SUPERFAMILY SSF53633 13 260 3.14E-57 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 SMART SM00359 281 360 9.9E-14 T 28-03-2018 IPR002478 PUA domain GO:0003723 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 Pfam PF00696 Amino acid kinase family 13 240 1.8E-40 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 SUPERFAMILY SSF88697 281 366 6.63E-18 T 28-03-2018 IPR015947 PUA-like domain CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 PIRSF PIRSF000729 7 369 4.8E-118 T 28-03-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 Gene3D G3DSA:2.30.130.10 279 367 7.6E-21 T 28-03-2018 IPR002478 PUA domain GO:0003723 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 TIGRFAM TIGR01027 proB: glutamate 5-kinase 13 366 1.3E-126 T 28-03-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 Pfam PF01472 PUA domain 281 348 1.4E-17 T 28-03-2018 IPR002478 PUA domain GO:0003723 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 Gene3D G3DSA:3.40.1160.10 1 269 6.1E-59 T 28-03-2018 CNX65_RS05930 be9b97270c72a72aa7c6169adb54be37 370 ProSitePatterns PS00902 Glutamate 5-kinase signature. 214 231 - T 28-03-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 CNX65_RS27970 8b55f3c66e7a0f3bc6957809c40c7b65 125 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 33 105 7.7E-35 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CNX65_RS27970 8b55f3c66e7a0f3bc6957809c40c7b65 125 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 7 110 31.704 T 28-03-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CNX65_RS27970 8b55f3c66e7a0f3bc6957809c40c7b65 125 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 56 110 3.0E-20 T 28-03-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 CNX65_RS27970 8b55f3c66e7a0f3bc6957809c40c7b65 125 SUPERFAMILY SSF141734 6 109 2.48E-46 T 28-03-2018 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 PIRSF PIRSF017184 3 463 1.7E-83 T 28-03-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 6 191 19.487 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 220 442 2.5E-46 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 203 464 19.468 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 402 412 - T 28-03-2018 IPR017953 Carbohydrate kinase, predicted, conserved site CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 Gene3D G3DSA:3.40.1190.20 203 465 6.4E-42 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 Pfam PF01256 Carbohydrate kinase 228 442 1.8E-55 T 28-03-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 Pfam PF03853 YjeF-related protein N-terminus 25 173 1.7E-36 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 SUPERFAMILY SSF53613 206 459 2.03E-51 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 SUPERFAMILY SSF64153 4 224 3.92E-46 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CNX65_RS32180 efb9f83d3f505c058c0e4cfb3434a8d3 465 Gene3D G3DSA:3.40.50.10260 3 202 7.2E-50 T 28-03-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 ProSitePatterns PS00455 Putative AMP-binding domain signature. 151 162 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 Gene3D G3DSA:3.40.50.980 157 312 2.2E-27 T 28-03-2018 CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 Gene3D G3DSA:3.40.50.980 2 156 1.3E-27 T 28-03-2018 CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 Gene3D G3DSA:2.30.38.10 313 396 2.1E-24 T 28-03-2018 CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 SUPERFAMILY SSF56801 7 497 4.58E-101 T 28-03-2018 CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 Pfam PF13193 AMP-binding enzyme C-terminal domain 413 487 3.2E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 Gene3D G3DSA:3.30.300.30 397 501 4.7E-19 T 28-03-2018 CNX65_RS20185 b06653108a03a805ebfb202c08b75808 501 Pfam PF00501 AMP-binding enzyme 16 403 2.6E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS24425 66b7c9557b6e8793700b9afd6764af07 312 SUPERFAMILY SSF53187 40 311 7.38E-71 T 28-03-2018 CNX65_RS24425 66b7c9557b6e8793700b9afd6764af07 312 Pfam PF04389 Peptidase family M28 97 304 4.3E-47 T 28-03-2018 IPR007484 Peptidase M28 CNX65_RS24425 66b7c9557b6e8793700b9afd6764af07 312 Gene3D G3DSA:3.40.630.10 32 312 2.8E-64 T 28-03-2018 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 Gene3D G3DSA:1.10.1660.10 59 127 2.4E-14 T 28-03-2018 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 Pfam PF13411 MerR HTH family regulatory protein 4 70 3.7E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 Gene3D G3DSA:1.10.1660.10 1 58 1.7E-22 T 28-03-2018 CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 SUPERFAMILY SSF46955 4 117 5.13E-32 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS31530 4510b4e79133e639b8e3ed12eaf49633 131 SMART SM00422 3 72 4.3E-23 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:3.40.366.10 730 849 1.5E-23 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF00550 Phosphopantetheine attachment site 1572 1637 3.9E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SUPERFAMILY SSF55048 675 737 5.1E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:3.10.129.10 898 1013 6.4E-7 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF08990 Erythronolide synthase docking 3 25 3.0E-8 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:3.40.47.10 25 295 3.9E-88 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SUPERFAMILY SSF47336 1564 1647 4.71E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SUPERFAMILY SSF53901 30 403 7.3E-105 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 291 406 4.9E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 555 842 3.4E-113 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 409 489 4.8E-12 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1293 1468 2.5E-42 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SMART SM00823 Phosphopantetheine attachment site 1570 1642 1.1E-34 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SMART SM00825 Beta-ketoacyl synthase 35 459 3.8E-226 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SMART SM00826 893 1049 4.9E-34 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:3.40.47.10 298 457 2.6E-58 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SMART SM01294 1571 1638 8.4E-6 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 196 212 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF00698 Acyl transferase domain 554 861 5.7E-82 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:1.10.1200.10 1546 1650 1.1E-21 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 33 283 9.7E-93 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:3.40.366.10 551 687 3.0E-41 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:3.40.50.720 1287 1523 3.9E-41 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SUPERFAMILY SSF52151 738 831 1.02E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SUPERFAMILY SSF52151 551 677 1.02E-65 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SUPERFAMILY SSF51735 1293 1532 5.04E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF14765 Polyketide synthase dehydratase 915 1138 1.8E-27 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Gene3D G3DSA:3.30.70.250 688 729 1.2E-16 T 28-03-2018 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 Pfam PF08659 KR domain 1293 1466 5.7E-49 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1597 1612 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15330 ec8bd3f2c87893f6e529b07a89731f98 1717 SUPERFAMILY SSF51735 1147 1280 1.91E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 SUPERFAMILY SSF52518 327 442 2.41E-6 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Gene3D G3DSA:3.40.50.920 469 602 1.4E-27 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 ProSitePatterns PS00801 Transketolase signature 1. 56 75 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 ProSitePatterns PS00802 Transketolase signature 2. 402 418 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Pfam PF02779 Transketolase, pyrimidine binding domain 298 454 7.6E-32 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 30 596 35.068 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Pfam PF02780 Transketolase, C-terminal domain 479 584 4.4E-20 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Gene3D G3DSA:3.40.50.970 23 279 3.1E-74 T 28-03-2018 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 SUPERFAMILY SSF52922 469 595 1.96E-21 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 SMART SM00861 296 460 1.9E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Gene3D G3DSA:3.40.50.970 280 460 5.7E-44 T 28-03-2018 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 SUPERFAMILY SSF52518 31 358 6.17E-63 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 226 267 5.0E-8 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS24765 26a9fa764fad9aeed611d766bb20ede2 620 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 31 223 4.3E-79 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 Pfam PF00553 Cellulose binding domain 806 906 1.4E-32 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 SUPERFAMILY SSF110296 471 774 1.57E-34 T 28-03-2018 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 SUPERFAMILY SSF49384 801 906 3.49E-34 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 SUPERFAMILY SSF110296 58 463 1.18E-79 T 28-03-2018 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 Gene3D G3DSA:2.130.10.10 473 785 2.2E-60 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 Gene3D G3DSA:2.130.10.10 67 472 4.4E-89 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 SMART SM00637 806 906 9.8E-49 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS08930 553fc432e12e11ae2e17868ffda40a72 909 Gene3D G3DSA:2.60.40.290 795 906 2.6E-36 T 28-03-2018 CNX65_RS24730 fb3dad48099bc1d320f7d0fb10b37825 256 Pfam PF04199 Putative cyclase 43 193 3.6E-27 T 28-03-2018 IPR007325 Kynurenine formamidase GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 CNX65_RS24730 fb3dad48099bc1d320f7d0fb10b37825 256 Gene3D G3DSA:3.50.30.50 20 255 5.3E-43 T 28-03-2018 CNX65_RS24730 fb3dad48099bc1d320f7d0fb10b37825 256 SUPERFAMILY SSF102198 22 251 2.75E-39 T 28-03-2018 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 SMART SM00997 249 411 5.6E-107 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 13 483 48.266 T 28-03-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 SUPERFAMILY SSF51735 249 411 2.68E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 PIRSF PIRSF001109 7 491 5.4E-189 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 18 483 1.1E-190 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 249 411 1.3E-79 T 28-03-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 SMART SM00996 17 490 0.0 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 89 103 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 Gene3D G3DSA:3.40.50.1480 264 464 2.3E-81 T 28-03-2018 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 SUPERFAMILY SSF52283 412 491 4.48E-111 T 28-03-2018 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 SUPERFAMILY SSF52283 16 163 4.48E-111 T 28-03-2018 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 SUPERFAMILY SSF52283 201 248 4.48E-111 T 28-03-2018 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 271 287 - T 28-03-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013|GO:0006730 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 17 490 1.5E-144 T 28-03-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 CNX65_RS15715 738d9a0a15db0ef3b67d8b5e330a7b07 491 Gene3D G3DSA:3.40.50.1480 5 263 6.8E-109 T 28-03-2018 CNX65_RS18760 4d6f4d9d884142543c56f5ab08252a35 351 Gene3D G3DSA:1.10.10.60 306 340 1.2E-11 T 28-03-2018 CNX65_RS18760 4d6f4d9d884142543c56f5ab08252a35 351 Gene3D G3DSA:1.10.260.40 273 305 5.2E-4 T 28-03-2018 CNX65_RS18760 4d6f4d9d884142543c56f5ab08252a35 351 SMART SM00342 256 338 4.6E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS18760 4d6f4d9d884142543c56f5ab08252a35 351 SUPERFAMILY SSF46689 292 339 3.63E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS18760 4d6f4d9d884142543c56f5ab08252a35 351 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 32 213 6.6E-39 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CNX65_RS18760 4d6f4d9d884142543c56f5ab08252a35 351 Pfam PF12833 Helix-turn-helix domain 262 338 7.5E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS18760 4d6f4d9d884142543c56f5ab08252a35 351 Gene3D G3DSA:1.10.10.60 214 272 0.019 T 28-03-2018 CNX65_RS04805 4545aa1aa6fe9021a64b8d45e272d586 407 SUPERFAMILY SSF51713 358 406 5.23E-34 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CNX65_RS04805 4545aa1aa6fe9021a64b8d45e272d586 407 SUPERFAMILY SSF51713 32 278 5.23E-34 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CNX65_RS04805 4545aa1aa6fe9021a64b8d45e272d586 407 Gene3D G3DSA:3.20.20.105 35 407 5.8E-55 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Gene3D G3DSA:3.30.230.10 495 619 2.4E-43 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Gene3D G3DSA:3.30.70.240 620 697 1.1E-31 T 28-03-2018 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 SMART SM00889 482 604 1.2E-70 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Pfam PF03764 Elongation factor G, domain IV 481 604 1.4E-46 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Pfam PF14492 Elongation Factor G, domain II 406 480 1.7E-35 T 28-03-2018 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 SUPERFAMILY SSF54211 481 605 2.3E-40 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 SUPERFAMILY SSF54980 406 483 1.29E-25 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 SMART SM00838 606 693 3.9E-56 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 12 182 4.3E-33 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 SUPERFAMILY SSF52540 8 284 5.18E-110 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Gene3D G3DSA:3.30.70.870 402 494 1.1E-38 T 28-03-2018 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Pfam PF03144 Elongation factor Tu domain 2 326 392 2.6E-12 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Pfam PF00009 Elongation factor Tu GTP binding domain 11 284 1.2E-68 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 SUPERFAMILY SSF54980 609 695 4.8E-30 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Gene3D G3DSA:3.40.50.300 7 289 9.6E-60 T 28-03-2018 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Hamap MF_00054_B Elongation factor G [fusA]. 8 697 108.503 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Pfam PF00679 Elongation factor G C-terminus 607 692 2.9E-30 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 PRINTS PR00315 GTP-binding elongation factor signature 96 107 3.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 PRINTS PR00315 GTP-binding elongation factor signature 80 90 3.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 PRINTS PR00315 GTP-binding elongation factor signature 132 141 3.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.7E-16 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 Gene3D G3DSA:2.40.30.10 291 401 3.9E-26 T 28-03-2018 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 TIGRFAM TIGR00484 EF-G: translation elongation factor G 7 697 0.0 T 28-03-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS32465 c61f3bf11b594bf8effd269800a729f5 700 SUPERFAMILY SSF50447 267 406 3.81E-32 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 Gene3D G3DSA:1.10.10.10 127 218 3.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.2E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 SUPERFAMILY SSF52172 2 133 6.12E-34 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 Pfam PF00072 Response regulator receiver domain 4 115 1.7E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 SUPERFAMILY SSF46894 143 214 1.05E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 Gene3D G3DSA:3.40.50.2300 1 126 1.9E-35 T 28-03-2018 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 8.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 8.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 8.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 SMART SM00421 152 209 6.8E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 SMART SM00448 2 115 6.4E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS28915 20065e7eaf9f419c01aa158786f8b906 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 3 422 42.629 T 28-03-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 Pfam PF00579 tRNA synthetases class I (W and Y) 31 325 2.9E-78 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 51 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 Gene3D G3DSA:3.10.290.10 327 424 1.6E-22 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 SUPERFAMILY SSF52374 4 325 1.08E-95 T 28-03-2018 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 4 421 1.4E-107 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 Gene3D G3DSA:1.10.240.10 224 326 2.5E-28 T 28-03-2018 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 Gene3D G3DSA:3.40.50.620 1 223 2.6E-63 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 SMART SM00363 357 418 4.9E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 217 229 4.5E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 45 67 4.5E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 163 178 4.5E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 184 206 4.5E-27 T 28-03-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 CNX65_RS27125 40bcf69bd61c8fd4ff3afd2770717cd9 424 SUPERFAMILY SSF55174 328 421 6.28E-16 T 28-03-2018 CNX65_RS33225 deb77b8d5c6092b8448c6b60136c4137 33 SMART SM01155 1 33 3.3E-6 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS33225 deb77b8d5c6092b8448c6b60136c4137 33 Pfam PF08213 Mitochondrial domain of unknown function (DUF1713) 1 33 1.9E-9 T 28-03-2018 IPR013177 Domain of unknown function DUF1713 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 SUPERFAMILY SSF81271 275 359 8.28E-35 T 28-03-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 SUPERFAMILY SSF52540 3 297 1.31E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 Gene3D G3DSA:3.10.20.30 259 358 3.2E-44 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 3 359 1.1E-129 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 359 42.638 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 1.0E-33 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 Gene3D G3DSA:3.40.50.300 2 80 3.0E-8 T 28-03-2018 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 Gene3D G3DSA:1.10.150.300 110 198 3.6E-24 T 28-03-2018 IPR023192 TGS-like domain Reactome: R-HSA-114608 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 Pfam PF01926 50S ribosome-binding GTPase 5 124 2.2E-21 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 Pfam PF06071 Protein of unknown function (DUF933) 275 358 3.9E-39 T 28-03-2018 IPR013029 Domain of unknown function DUF933 Reactome: R-HSA-114608 CNX65_RS03665 845c40a3aba04a8697962006281d592f 359 PIRSF PIRSF006641 1 359 8.0E-139 T 28-03-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 CNX65_RS11325 ecd84ed925025d669c49c36d1cd3f963 414 Gene3D G3DSA:3.30.565.10 289 414 4.1E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11325 ecd84ed925025d669c49c36d1cd3f963 414 SUPERFAMILY SSF55874 289 400 1.02E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11325 ecd84ed925025d669c49c36d1cd3f963 414 Pfam PF07730 Histidine kinase 219 284 1.2E-16 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 337 443 2.9E-23 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 39 54 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 255 269 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 297 304 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 418 438 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 333 354 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 4.4E-66 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PIRSF PIRSF000350 2 427 3.6E-71 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 6 454 5.9E-143 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 Gene3D G3DSA:3.30.390.30 327 450 3.2E-30 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 SUPERFAMILY SSF51905 3 327 9.97E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 Gene3D G3DSA:3.40.50.720 160 326 8.9E-40 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 40 50 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 317 2.9E-74 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 Gene3D G3DSA:3.50.50.60 1 159 2.4E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 SUPERFAMILY SSF55424 334 454 8.25E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 282 304 2.5E-38 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 270 2.5E-38 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 2.5E-38 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 2.5E-38 T 28-03-2018 CNX65_RS06680 baebd0c7790d8cf9b5e5db2724383ced 456 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 2.5E-38 T 28-03-2018 CNX65_RS16570 da7cd7c537866eb4278918f8cbfc05fc 432 SUPERFAMILY SSF49384 326 431 1.46E-30 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS16570 da7cd7c537866eb4278918f8cbfc05fc 432 SUPERFAMILY SSF53474 42 281 5.7E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16570 da7cd7c537866eb4278918f8cbfc05fc 432 Pfam PF00553 Cellulose binding domain 334 429 2.5E-26 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16570 da7cd7c537866eb4278918f8cbfc05fc 432 Gene3D G3DSA:2.60.40.290 321 429 1.6E-32 T 28-03-2018 CNX65_RS16570 da7cd7c537866eb4278918f8cbfc05fc 432 Gene3D G3DSA:3.40.50.1820 49 304 1.0E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16570 da7cd7c537866eb4278918f8cbfc05fc 432 SMART SM00637 330 429 2.2E-38 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 SMART SM00382 198 337 2.8E-25 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 ProSitePatterns PS00674 AAA-protein family signature. 305 323 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 115 605 1.0E-228 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 SUPERFAMILY SSF52540 158 405 7.04E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 Pfam PF01434 Peptidase family M41 398 604 1.2E-78 T 28-03-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 202 333 1.1E-45 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 Gene3D G3DSA:3.40.50.300 139 346 9.7E-65 T 28-03-2018 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 5 613 36.619 T 28-03-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 SUPERFAMILY SSF140990 416 609 6.93E-69 T 28-03-2018 CNX65_RS01610 9ee0c88a30e5a9f4a7b5556c04ba0ebe 743 Gene3D G3DSA:1.10.8.60 347 428 2.6E-20 T 28-03-2018 CNX65_RS03105 c7b3bb6a0cb0a84ba2d5c34cae4bb936 98 Gene3D G3DSA:2.20.25.10 2 17 0.043 T 28-03-2018 CNX65_RS03105 c7b3bb6a0cb0a84ba2d5c34cae4bb936 98 SMART SM00834 2 41 1.0E-13 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CNX65_RS03105 c7b3bb6a0cb0a84ba2d5c34cae4bb936 98 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 51 4.0E-20 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CNX65_RS03105 c7b3bb6a0cb0a84ba2d5c34cae4bb936 98 Pfam PF09723 Zinc ribbon domain 2 39 1.2E-14 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CNX65_RS18995 a9d55179f54acd164c565cba21aeb003 143 Pfam PF01638 HxlR-like helix-turn-helix 14 100 3.5E-26 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS18995 a9d55179f54acd164c565cba21aeb003 143 SUPERFAMILY SSF46785 3 135 8.86E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18995 a9d55179f54acd164c565cba21aeb003 143 Gene3D G3DSA:1.10.10.10 1 142 1.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16445 c4244ec39deddbf7c5166f1b2426cf90 237 SUPERFAMILY SSF51735 4 226 6.96E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16445 c4244ec39deddbf7c5166f1b2426cf90 237 Gene3D G3DSA:3.40.50.720 3 229 8.5E-35 T 28-03-2018 CNX65_RS16445 c4244ec39deddbf7c5166f1b2426cf90 237 Pfam PF00106 short chain dehydrogenase 5 190 1.2E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS09255 684ddba89e806130f342c1c8fd8885f3 323 Gene3D G3DSA:1.10.3470.10 2 309 4.0E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS09255 684ddba89e806130f342c1c8fd8885f3 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 40 303 2.7E-39 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS21830 153ac9de94bd23d84dc73eaa8d8f42f8 462 Gene3D G3DSA:3.40.50.2000 245 424 2.5E-21 T 28-03-2018 CNX65_RS21830 153ac9de94bd23d84dc73eaa8d8f42f8 462 SUPERFAMILY SSF53756 2 126 1.34E-43 T 28-03-2018 CNX65_RS21830 153ac9de94bd23d84dc73eaa8d8f42f8 462 SUPERFAMILY SSF53756 172 439 1.34E-43 T 28-03-2018 CNX65_RS21830 153ac9de94bd23d84dc73eaa8d8f42f8 462 Gene3D G3DSA:3.40.50.2000 1 201 7.7E-24 T 28-03-2018 CNX65_RS18375 c7ab73d41855ad4523a8a32f4a8d5b3a 76 Pfam PF00550 Phosphopantetheine attachment site 4 65 3.4E-4 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18375 c7ab73d41855ad4523a8a32f4a8d5b3a 76 SUPERFAMILY SSF47336 3 72 2.49E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18375 c7ab73d41855ad4523a8a32f4a8d5b3a 76 Gene3D G3DSA:1.10.1200.10 1 75 1.4E-10 T 28-03-2018 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Gene3D G3DSA:2.60.120.260 37 244 2.6E-46 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 781 919 6.4E-46 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 624 762 1.0E-47 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 SUPERFAMILY SSF49303 237 323 1.27E-10 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 SUPERFAMILY SSF110221 768 925 9.81E-46 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Gene3D G3DSA:2.60.40.10 245 323 1.1E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 SUPERFAMILY SSF51445 319 603 5.53E-53 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Pfam PF00703 Glycosyl hydrolases family 2 271 322 2.1E-6 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Gene3D G3DSA:3.20.20.80 333 603 1.0E-32 T 28-03-2018 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Gene3D G3DSA:2.80.10.50 769 926 4.8E-46 T 28-03-2018 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Gene3D G3DSA:2.80.10.50 609 768 9.1E-49 T 28-03-2018 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 SUPERFAMILY SSF110221 615 763 6.28E-47 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 Pfam PF02837 Glycosyl hydrolases family 2, sugar binding domain 111 229 3.2E-17 T 28-03-2018 IPR006104 Glycosyl hydrolases family 2, sugar binding domain GO:0004553|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS09350 d232661d909d6e4df87ee3461152f1fb 926 SUPERFAMILY SSF49785 65 232 2.19E-49 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS14885 56a0e5a54d62f12eac2de20f63473691 144 Gene3D G3DSA:3.40.50.620 1 144 1.5E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS14885 56a0e5a54d62f12eac2de20f63473691 144 Pfam PF00582 Universal stress protein family 4 142 3.0E-21 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS14885 56a0e5a54d62f12eac2de20f63473691 144 PRINTS PR01438 Universal stress protein signature 3 21 5.6E-7 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS14885 56a0e5a54d62f12eac2de20f63473691 144 PRINTS PR01438 Universal stress protein signature 120 142 5.6E-7 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS14885 56a0e5a54d62f12eac2de20f63473691 144 SUPERFAMILY SSF52402 4 142 1.34E-23 T 28-03-2018 CNX65_RS28390 f39d9267fbc238d9c3e45d589633debb 237 Gene3D G3DSA:3.40.50.720 1 230 3.6E-29 T 28-03-2018 CNX65_RS28390 f39d9267fbc238d9c3e45d589633debb 237 SUPERFAMILY SSF51735 3 225 2.37E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS28390 f39d9267fbc238d9c3e45d589633debb 237 Pfam PF00106 short chain dehydrogenase 3 185 2.5E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24380 baa24b416f5f2889dd1bdab790c3dbe8 456 Pfam PF15892 BNR repeat-containing family member 59 364 4.9E-79 T 28-03-2018 CNX65_RS24380 baa24b416f5f2889dd1bdab790c3dbe8 456 Gene3D G3DSA:2.120.10.10 214 446 7.2E-7 T 28-03-2018 CNX65_RS33830 754ff0bc1092692461fbb282595135f3 235 Pfam PF00027 Cyclic nucleotide-binding domain 38 122 5.5E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS33830 754ff0bc1092692461fbb282595135f3 235 Gene3D G3DSA:2.60.120.10 10 152 7.3E-21 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS33830 754ff0bc1092692461fbb282595135f3 235 SUPERFAMILY SSF46785 155 233 1.49E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33830 754ff0bc1092692461fbb282595135f3 235 Pfam PF13545 Crp-like helix-turn-helix domain 157 231 2.0E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS33830 754ff0bc1092692461fbb282595135f3 235 Gene3D G3DSA:1.10.10.10 153 234 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33830 754ff0bc1092692461fbb282595135f3 235 SMART SM00100 19 137 5.3E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS33830 754ff0bc1092692461fbb282595135f3 235 SUPERFAMILY SSF51206 15 149 4.98E-22 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS24405 2a5d8fc0fb684415e1704395067b5aab 212 Pfam PF01066 CDP-alcohol phosphatidyltransferase 37 101 4.6E-9 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 SUPERFAMILY SSF55073 373 526 6.12E-37 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 SMART SM00267 357 525 1.4E-48 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 Gene3D G3DSA:3.30.70.270 380 532 5.3E-48 T 28-03-2018 CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 Gene3D G3DSA:3.30.450.20 248 379 9.6E-8 T 28-03-2018 CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 Gene3D G3DSA:3.20.20.450 533 782 5.1E-90 T 28-03-2018 IPR001633 EAL domain CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 SMART SM00052 535 779 1.1E-94 T 28-03-2018 IPR001633 EAL domain CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 SUPERFAMILY SSF141868 542 773 2.48E-78 T 28-03-2018 IPR001633 EAL domain CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 365 522 5.5E-29 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 Pfam PF00563 EAL domain 542 773 6.9E-68 T 28-03-2018 IPR001633 EAL domain CNX65_RS12935 6352b47f766faaa8d46fa6eec71c7f22 786 Pfam PF00990 Diguanylate cyclase, GGDEF domain 370 519 2.2E-33 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS00340 5f320e6774cb9ca1344c0b6baa687da8 419 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 293 392 9.2E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00340 5f320e6774cb9ca1344c0b6baa687da8 419 Gene3D G3DSA:3.30.565.10 177 392 5.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00340 5f320e6774cb9ca1344c0b6baa687da8 419 Gene3D G3DSA:3.30.450.40 35 176 2.3E-5 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS00340 5f320e6774cb9ca1344c0b6baa687da8 419 SUPERFAMILY SSF55874 250 391 2.23E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00340 5f320e6774cb9ca1344c0b6baa687da8 419 SMART SM00387 284 394 1.1E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00340 5f320e6774cb9ca1344c0b6baa687da8 419 Pfam PF06580 Histidine kinase 195 273 1.8E-23 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CNX65_RS05970 c7af045bef8cdecb9428a348e518cb75 148 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 13 108 6.2E-32 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CNX65_RS05970 c7af045bef8cdecb9428a348e518cb75 148 SUPERFAMILY SSF81301 8 117 3.76E-39 T 28-03-2018 CNX65_RS05970 c7af045bef8cdecb9428a348e518cb75 148 Pfam PF02410 Ribosomal silencing factor during starvation 15 108 1.2E-23 T 28-03-2018 CNX65_RS05970 c7af045bef8cdecb9428a348e518cb75 148 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 4 109 23.95 T 28-03-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS CNX65_RS05970 c7af045bef8cdecb9428a348e518cb75 148 Gene3D G3DSA:3.30.460.10 4 112 8.1E-32 T 28-03-2018 CNX65_RS33985 893485e70d708091314913a70800ecf1 752 SUPERFAMILY SSF56042 211 441 1.94E-52 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 SUPERFAMILY SSF55326 18 202 9.12E-49 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Pfam PF02769 AIR synthase related protein, C-terminal domain 212 369 2.5E-33 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Pfam PF02769 AIR synthase related protein, C-terminal domain 588 723 6.1E-18 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Gene3D G3DSA:3.90.650.10 190 384 2.0E-36 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 SUPERFAMILY SSF55326 427 581 3.66E-54 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 748 5.7E-254 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33985 893485e70d708091314913a70800ecf1 752 SUPERFAMILY SSF56042 587 751 1.17E-33 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 752 307.721 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Gene3D G3DSA:3.90.650.10 583 752 3.0E-33 T 28-03-2018 IPR010918 AIR synthase-related protein, C-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Pfam PF00586 AIR synthase related protein, N-terminal domain 469 574 7.7E-25 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Pfam PF00586 AIR synthase related protein, N-terminal domain 97 198 4.0E-22 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 PIRSF PIRSF001587 9 752 9.1E-284 T 28-03-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Gene3D G3DSA:3.30.1330.10 412 579 1.8E-46 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS33985 893485e70d708091314913a70800ecf1 752 Gene3D G3DSA:3.30.1330.10 22 189 2.9E-53 T 28-03-2018 IPR016188 PurM-like, N-terminal domain CNX65_RS09400 487c58f6b9ddcc1883c6e5bc9f6ed420 310 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 117 1.3E-38 T 28-03-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CNX65_RS09400 487c58f6b9ddcc1883c6e5bc9f6ed420 310 Pfam PF14572 Phosphoribosyl synthetase-associated domain 201 308 2.7E-18 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CNX65_RS09400 487c58f6b9ddcc1883c6e5bc9f6ed420 310 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 309 1.8E-91 T 28-03-2018 IPR005946 Ribose-phosphate diphosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 CNX65_RS09400 487c58f6b9ddcc1883c6e5bc9f6ed420 310 SMART SM01400 1 117 4.0E-62 T 28-03-2018 CNX65_RS09400 487c58f6b9ddcc1883c6e5bc9f6ed420 310 SUPERFAMILY SSF53271 66 301 2.14E-44 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS09400 487c58f6b9ddcc1883c6e5bc9f6ed420 310 Gene3D G3DSA:3.40.50.2020 143 310 5.1E-37 T 28-03-2018 CNX65_RS09400 487c58f6b9ddcc1883c6e5bc9f6ed420 310 Gene3D G3DSA:3.40.50.2020 1 142 3.8E-52 T 28-03-2018 CNX65_RS21640 34b832616c069911ca6d16af0097f247 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 311 2.5E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS21640 34b832616c069911ca6d16af0097f247 325 SUPERFAMILY SSF161098 98 299 7.98E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS21640 34b832616c069911ca6d16af0097f247 325 Gene3D G3DSA:1.10.3720.10 5 300 6.7E-31 T 28-03-2018 CNX65_RS02430 c80645c46e489c5a97c8f0b8cbd1892c 222 Gene3D G3DSA:1.10.10.60 9 53 2.4E-11 T 28-03-2018 CNX65_RS02430 c80645c46e489c5a97c8f0b8cbd1892c 222 SUPERFAMILY SSF46689 31 102 3.74E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS02430 c80645c46e489c5a97c8f0b8cbd1892c 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 4.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02430 c80645c46e489c5a97c8f0b8cbd1892c 222 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 4.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02430 c80645c46e489c5a97c8f0b8cbd1892c 222 Pfam PF00440 Bacterial regulatory proteins, tetR family 33 79 3.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02430 c80645c46e489c5a97c8f0b8cbd1892c 222 Gene3D G3DSA:1.10.260.40 54 129 4.0E-11 T 28-03-2018 CNX65_RS00670 f5e740405cbf6712d3a56b509b414716 271 Pfam PF00005 ABC transporter 47 177 1.3E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS00670 f5e740405cbf6712d3a56b509b414716 271 SUPERFAMILY SSF52540 45 241 2.89E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00670 f5e740405cbf6712d3a56b509b414716 271 SMART SM00382 56 234 1.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS00670 f5e740405cbf6712d3a56b509b414716 271 Gene3D G3DSA:3.40.50.300 3 268 1.9E-41 T 28-03-2018 CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 SUPERFAMILY SSF52833 3 103 2.45E-34 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 Gene3D G3DSA:3.40.30.10 1 130 6.3E-36 T 28-03-2018 CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 102 5.3E-32 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 PRINTS PR00421 Thioredoxin family signature 68 79 1.6E-7 T 28-03-2018 CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 PRINTS PR00421 Thioredoxin family signature 29 38 1.6E-7 T 28-03-2018 CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 PRINTS PR00421 Thioredoxin family signature 21 29 1.6E-7 T 28-03-2018 CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 ProSitePatterns PS00194 Thioredoxin family active site. 22 40 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CNX65_RS08850 1750ef3fcc298d2d8f76ad1419bcc450 131 Pfam PF00085 Thioredoxin 4 102 1.1E-28 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CNX65_RS32165 5f43d8ca1093f00f686e968ad6a25fe4 169 Gene3D G3DSA:3.40.50.300 1 147 4.3E-42 T 28-03-2018 CNX65_RS32165 5f43d8ca1093f00f686e968ad6a25fe4 169 SUPERFAMILY SSF52540 19 122 1.13E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32165 5f43d8ca1093f00f686e968ad6a25fe4 169 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 6 132 5.3E-22 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CNX65_RS32165 5f43d8ca1093f00f686e968ad6a25fe4 169 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 4 125 2.3E-29 T 28-03-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 CNX65_RS16375 c1af9dd419fe934ea3ff48375bbf8d5d 460 SMART SM00606 331 460 1.3E-42 T 28-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 CNX65_RS16375 c1af9dd419fe934ea3ff48375bbf8d5d 460 SUPERFAMILY SSF49785 330 459 1.87E-33 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS16375 c1af9dd419fe934ea3ff48375bbf8d5d 460 Gene3D G3DSA:2.115.10.20 31 324 3.2E-62 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16375 c1af9dd419fe934ea3ff48375bbf8d5d 460 Gene3D G3DSA:2.60.120.260 327 460 4.1E-30 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS16375 c1af9dd419fe934ea3ff48375bbf8d5d 460 SUPERFAMILY SSF75005 33 316 3.62E-67 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16375 c1af9dd419fe934ea3ff48375bbf8d5d 460 Pfam PF04616 Glycosyl hydrolases family 43 35 316 1.8E-49 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS16375 c1af9dd419fe934ea3ff48375bbf8d5d 460 Pfam PF03422 Carbohydrate binding module (family 6) 339 459 3.3E-35 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 Pfam PF12852 Cupin 5 173 2.2E-29 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 SUPERFAMILY SSF46689 241 289 7.62E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 Gene3D G3DSA:2.60.120.280 30 164 1.2E-11 T 28-03-2018 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 Pfam PF12833 Helix-turn-helix domain 211 287 3.0E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 SUPERFAMILY SSF46689 191 239 1.48E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 SMART SM00342 205 287 1.5E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 256 271 9.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 271 287 9.3E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 Gene3D G3DSA:1.10.10.60 165 243 5.0E-8 T 28-03-2018 CNX65_RS16950 22779ab8020c635aa39e9e2162c3bdda 294 Gene3D G3DSA:1.10.10.60 244 294 3.6E-12 T 28-03-2018 CNX65_RS25445 c7580e55b777403742908abd610653c1 252 Pfam PF01551 Peptidase family M23 146 241 1.3E-30 T 28-03-2018 IPR016047 Peptidase M23 CNX65_RS25445 c7580e55b777403742908abd610653c1 252 Gene3D G3DSA:2.70.70.10 81 248 1.6E-48 T 28-03-2018 CNX65_RS25445 c7580e55b777403742908abd610653c1 252 SUPERFAMILY SSF51261 100 245 9.42E-49 T 28-03-2018 IPR011055 Duplicated hybrid motif CNX65_RS32450 584247296cebc9e55472fb5f22d48567 216 Gene3D G3DSA:4.10.960.10 62 170 5.0E-37 T 28-03-2018 CNX65_RS32450 584247296cebc9e55472fb5f22d48567 216 Pfam PF00297 Ribosomal protein L3 99 187 1.4E-17 T 28-03-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32450 584247296cebc9e55472fb5f22d48567 216 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 8 209 1.2E-90 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32450 584247296cebc9e55472fb5f22d48567 216 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 6 212 40.389 T 28-03-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32450 584247296cebc9e55472fb5f22d48567 216 ProSitePatterns PS00474 Ribosomal protein L3 signature. 106 129 - T 28-03-2018 IPR019926 Ribosomal protein L3, conserved site CNX65_RS32450 584247296cebc9e55472fb5f22d48567 216 SUPERFAMILY SSF50447 5 213 1.06E-81 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS00915 e3a7c031215263960de2b57675e5a9be 322 SUPERFAMILY SSF53807 35 292 3.92E-51 T 28-03-2018 CNX65_RS00915 e3a7c031215263960de2b57675e5a9be 322 Pfam PF01497 Periplasmic binding protein 57 288 1.6E-21 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS00915 e3a7c031215263960de2b57675e5a9be 322 Gene3D G3DSA:3.40.50.1980 25 160 6.0E-33 T 28-03-2018 CNX65_RS00915 e3a7c031215263960de2b57675e5a9be 322 Gene3D G3DSA:3.40.50.1980 161 320 5.5E-24 T 28-03-2018 CNX65_RS30375 eac235efaf54a71fb47650ac227e63d1 128 SUPERFAMILY SSF47413 19 75 4.74E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS30375 eac235efaf54a71fb47650ac227e63d1 128 Pfam PF01381 Helix-turn-helix 30 75 2.9E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS30375 eac235efaf54a71fb47650ac227e63d1 128 SMART SM00530 22 76 8.9E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS30375 eac235efaf54a71fb47650ac227e63d1 128 Gene3D G3DSA:1.10.260.40 11 81 9.3E-9 T 28-03-2018 CNX65_RS15870 98f4bdbb93ee85b9208f678b34abad3d 345 Gene3D G3DSA:3.40.47.10 42 165 8.3E-16 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15870 98f4bdbb93ee85b9208f678b34abad3d 345 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 244 334 9.3E-18 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS15870 98f4bdbb93ee85b9208f678b34abad3d 345 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 185 5.2E-6 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS15870 98f4bdbb93ee85b9208f678b34abad3d 345 Gene3D G3DSA:3.40.47.10 166 335 3.2E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15870 98f4bdbb93ee85b9208f678b34abad3d 345 SUPERFAMILY SSF53901 41 335 1.34E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 SUPERFAMILY SSF47203 250 400 3.06E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 115 9.5E-15 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 SUPERFAMILY SSF56645 5 234 1.7E-53 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 357 376 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 Gene3D G3DSA:1.20.140.10 223 403 4.0E-51 T 28-03-2018 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 126 223 2.9E-22 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 Gene3D G3DSA:1.10.540.10 2 117 1.5E-20 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 Gene3D G3DSA:2.40.110.10 125 222 2.7E-31 T 28-03-2018 CNX65_RS34475 d2484c585d612fc5e00d681e33e50244 404 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 398 1.4E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 SMART SM00388 235 307 2.8E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 SMART SM00387 348 462 3.9E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 Gene3D G3DSA:1.10.287.130 225 303 6.0E-14 T 28-03-2018 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 348 459 1.0E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 SUPERFAMILY SSF158472 185 231 2.22E-5 T 28-03-2018 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 SUPERFAMILY SSF47384 218 308 1.26E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 Pfam PF00672 HAMP domain 182 230 5.2E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 SUPERFAMILY SSF55874 309 462 5.11E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 SMART SM00304 182 234 3.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 Gene3D G3DSA:3.30.565.10 309 468 2.4E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 306 2.5E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 407 417 4.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 446 459 4.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 389 403 4.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS03045 a184593d6c5bf39284c7900044a2a601 476 PRINTS PR00344 Bacterial sensor protein C-terminal signature 422 440 4.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS10750 89a3f7a9b07473a4a881a2570402e7e5 251 Gene3D G3DSA:1.10.10.200 1 78 4.4E-29 T 28-03-2018 IPR017856 Integrase, N-terminal zinc-binding domain-like CNX65_RS10750 89a3f7a9b07473a4a881a2570402e7e5 251 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 241 34.632 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS10750 89a3f7a9b07473a4a881a2570402e7e5 251 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 239 1.1E-97 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS10750 89a3f7a9b07473a4a881a2570402e7e5 251 Gene3D G3DSA:3.30.70.980 84 180 1.2E-30 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS10750 89a3f7a9b07473a4a881a2570402e7e5 251 Gene3D G3DSA:3.30.70.980 181 250 2.4E-11 T 28-03-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS10750 89a3f7a9b07473a4a881a2570402e7e5 251 Pfam PF01709 Transcriptional regulator 5 239 1.2E-87 T 28-03-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS10750 89a3f7a9b07473a4a881a2570402e7e5 251 SUPERFAMILY SSF75625 3 248 8.37E-89 T 28-03-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00943 Copper-transporting ATPase signature 204 223 2.5E-5 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00943 Copper-transporting ATPase signature 357 371 2.5E-5 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00943 Copper-transporting ATPase signature 417 432 2.5E-5 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00943 Copper-transporting ATPase signature 606 623 2.5E-5 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 208 709 7.1E-82 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 Pfam PF00122 E1-E2 ATPase 237 412 4.1E-51 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 ProSitePatterns PS01047 Heavy-metal-associated domain. 15 43 - T 28-03-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 Gene3D G3DSA:3.30.70.100 8 75 3.8E-20 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 652 664 3.0E-23 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 554 565 3.0E-23 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 284 298 3.0E-23 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 576 586 3.0E-23 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 648 3.0E-23 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 448 3.0E-23 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 ProSitePatterns PS01229 Hypothetical cof family signature 2. 629 651 - T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 SUPERFAMILY SSF81653 240 334 1.11E-23 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 Pfam PF00702 haloacid dehalogenase-like hydrolase 430 643 8.1E-46 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 SUPERFAMILY SSF81665 335 428 1.44E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 SUPERFAMILY SSF81665 202 238 1.44E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 SUPERFAMILY SSF81665 678 704 1.44E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 SUPERFAMILY SSF55008 5 76 1.06E-19 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 203 731 5.6E-113 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 Gene3D G3DSA:3.40.50.1000 556 688 4.2E-38 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 154 731 4.9E-173 T 28-03-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 Gene3D G3DSA:3.40.1110.10 449 555 1.9E-26 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 SUPERFAMILY SSF56784 432 452 3.57E-56 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 SUPERFAMILY SSF56784 526 729 3.57E-56 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 199 732 8.4E-153 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 Pfam PF00403 Heavy-metal-associated domain 13 70 3.4E-13 T 28-03-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 Gene3D G3DSA:1.20.1110.10 197 448 1.1E-44 T 28-03-2018 CNX65_RS33520 1a3c551369167e1be646a05dd7f87882 739 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 436 442 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CNX65_RS13215 ac8d59367a8548eaa6290102b65486ba 184 SUPERFAMILY SSF52091 70 178 8.24E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS13215 ac8d59367a8548eaa6290102b65486ba 184 Pfam PF01740 STAS domain 74 165 1.5E-10 T 28-03-2018 IPR002645 STAS domain CNX65_RS13215 ac8d59367a8548eaa6290102b65486ba 184 Gene3D G3DSA:3.30.750.24 67 181 2.7E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 Gene3D G3DSA:3.40.50.300 454 752 9.7E-54 T 28-03-2018 CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 Pfam PF00005 ABC transporter 469 671 2.7E-10 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 Gene3D G3DSA:1.20.1580.10 98 130 4.3E-7 T 28-03-2018 CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 SUPERFAMILY SSF52540 463 724 1.85E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 SUPERFAMILY SSF52540 13 167 2.35E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 SUPERFAMILY SSF52540 281 420 2.35E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 Gene3D G3DSA:1.10.8.280 152 243 3.5E-20 T 28-03-2018 CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 Gene3D G3DSA:3.40.50.300 9 70 2.4E-7 T 28-03-2018 CNX65_RS17890 dbdceb7602ba1ac1e24fc0bdc4edb58c 754 Gene3D G3DSA:3.40.50.300 244 426 1.2E-25 T 28-03-2018 CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 70 85 1.0E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 1.0E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 39 1.0E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 SMART SM00418 22 99 3.6E-17 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 Pfam PF12840 Helix-turn-helix domain 23 75 3.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 SUPERFAMILY SSF46785 11 99 1.15E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 Gene3D G3DSA:1.10.10.10 20 62 9.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27035 2f637864a4cad665940479e5aeb34627 116 Gene3D G3DSA:1.10.10.10 63 101 1.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 Gene3D G3DSA:1.10.10.10 3 85 3.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 Gene3D G3DSA:3.40.190.10 175 252 9.8E-8 T 28-03-2018 CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 TIGRFAM TIGR03298 argP: transcriptional regulator, ArgP family 6 284 4.1E-92 T 28-03-2018 IPR017685 HTH-type transcriptional regulator ArgP CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 1.2E-15 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 SUPERFAMILY SSF46785 7 95 5.45E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 SUPERFAMILY SSF53850 95 283 7.96E-15 T 28-03-2018 CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 Pfam PF03466 LysR substrate binding domain 111 282 5.3E-9 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS25225 49791a09e4e98813a0e3e9a65837bd01 288 Gene3D G3DSA:3.40.190.10 92 174 6.5E-37 T 28-03-2018 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 39 76 6.0E-15 T 28-03-2018 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 8 144 32.046 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 Gene3D G3DSA:1.10.10.250 75 143 1.3E-24 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 Pfam PF03946 Ribosomal protein L11, N-terminal domain 12 69 9.0E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 6 143 3.3E-62 T 28-03-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 ProSitePatterns PS00359 Ribosomal protein L11 signature. 129 144 - T 28-03-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 SUPERFAMILY SSF46906 70 143 9.55E-27 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 SUPERFAMILY SSF54747 5 75 2.49E-29 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 Pfam PF00298 Ribosomal protein L11, RNA binding domain 74 142 2.1E-25 T 28-03-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 SMART SM00649 12 143 4.4E-85 T 28-03-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32580 282687670c516b3ea1809b43edf94b36 144 Gene3D G3DSA:3.30.1550.10 6 74 3.3E-35 T 28-03-2018 IPR020784 Ribosomal protein L11, N-terminal CNX65_RS13280 6ceb9dc29b829dce3360993da92fced0 97 SMART SM00418 4 89 2.3E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS13280 6ceb9dc29b829dce3360993da92fced0 97 SUPERFAMILY SSF46785 4 85 3.52E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13280 6ceb9dc29b829dce3360993da92fced0 97 Gene3D G3DSA:1.10.10.10 10 53 5.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13280 6ceb9dc29b829dce3360993da92fced0 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 6 21 3.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS13280 6ceb9dc29b829dce3360993da92fced0 97 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 3.3E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS13280 6ceb9dc29b829dce3360993da92fced0 97 Gene3D G3DSA:1.10.10.10 54 89 9.0E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13280 6ceb9dc29b829dce3360993da92fced0 97 Pfam PF12840 Helix-turn-helix domain 3 69 4.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10430 32800e6221e8b1b25f401e1acd771c51 397 Gene3D G3DSA:1.20.1250.20 204 395 3.4E-26 T 28-03-2018 CNX65_RS10430 32800e6221e8b1b25f401e1acd771c51 397 Pfam PF07690 Major Facilitator Superfamily 20 354 1.9E-35 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS10430 32800e6221e8b1b25f401e1acd771c51 397 Gene3D G3DSA:1.20.1250.20 3 203 3.9E-28 T 28-03-2018 CNX65_RS10430 32800e6221e8b1b25f401e1acd771c51 397 SUPERFAMILY SSF103473 9 394 2.75E-59 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19270 f06c9e257cc1bab364ddc4e34f9758da 817 Pfam PF04738 Lantibiotic dehydratase, C terminus 146 581 8.8E-19 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CNX65_RS00200 4d06207328d47135d59c718045800678 460 SMART SM00530 32 87 6.4E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS00200 4d06207328d47135d59c718045800678 460 Gene3D G3DSA:3.30.1190.10 51 112 2.5E-5 T 28-03-2018 CNX65_RS00200 4d06207328d47135d59c718045800678 460 Gene3D G3DSA:1.10.10.60 17 50 1.3E-5 T 28-03-2018 CNX65_RS00200 4d06207328d47135d59c718045800678 460 Gene3D G3DSA:1.25.40.10 194 253 2.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00200 4d06207328d47135d59c718045800678 460 Gene3D G3DSA:1.10.150.200 254 302 0.0016 T 28-03-2018 CNX65_RS00200 4d06207328d47135d59c718045800678 460 SMART SM00028 252 285 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00200 4d06207328d47135d59c718045800678 460 SMART SM00028 212 245 24.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00200 4d06207328d47135d59c718045800678 460 SUPERFAMILY SSF47413 32 85 2.67E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS00200 4d06207328d47135d59c718045800678 460 SUPERFAMILY SSF48452 208 415 1.66E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00200 4d06207328d47135d59c718045800678 460 Pfam PF13560 Helix-turn-helix domain 37 84 4.4E-8 T 28-03-2018 CNX65_RS00200 4d06207328d47135d59c718045800678 460 Gene3D G3DSA:1.25.40.10 303 447 0.016 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS12400 d189dc2ac1b60ac3508c1de01d494f63 224 Gene3D G3DSA:1.10.357.10 17 210 1.6E-28 T 28-03-2018 CNX65_RS12400 d189dc2ac1b60ac3508c1de01d494f63 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 49 1.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12400 d189dc2ac1b60ac3508c1de01d494f63 224 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 1.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12400 d189dc2ac1b60ac3508c1de01d494f63 224 Pfam PF00440 Bacterial regulatory proteins, tetR family 36 81 7.4E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12400 d189dc2ac1b60ac3508c1de01d494f63 224 SUPERFAMILY SSF46689 24 102 1.85E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12400 d189dc2ac1b60ac3508c1de01d494f63 224 SUPERFAMILY SSF48498 100 204 8.9E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS33375 a7e31aedd83be3c795226d85582bcda6 221 SUPERFAMILY SSF53474 8 218 6.56E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS33375 a7e31aedd83be3c795226d85582bcda6 221 Gene3D G3DSA:3.40.50.1820 1 221 1.7E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 PRINTS PR00131 Glycosyl hydrolase family 1 signature 391 403 4.5E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 PRINTS PR00131 Glycosyl hydrolase family 1 signature 336 344 4.5E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 PRINTS PR00131 Glycosyl hydrolase family 1 signature 367 384 4.5E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 PRINTS PR00131 Glycosyl hydrolase family 1 signature 272 286 4.5E-14 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 Gene3D G3DSA:3.20.20.80 3 419 1.1E-124 T 28-03-2018 CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 SUPERFAMILY SSF51445 4 418 1.63E-127 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 Pfam PF00232 Glycosyl hydrolase family 1 5 417 1.7E-111 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS00175 b0f72d801bccf7cfbad3f8de98b915b8 419 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 6 20 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CNX65_RS34610 bc33a7f078f7857adaf9ce156cb841fd 610 Pfam PF00350 Dynamin family 45 196 3.1E-14 T 28-03-2018 IPR022812 Dynamin superfamily CNX65_RS34610 bc33a7f078f7857adaf9ce156cb841fd 610 Gene3D G3DSA:3.40.50.300 57 588 8.1E-27 T 28-03-2018 CNX65_RS34610 bc33a7f078f7857adaf9ce156cb841fd 610 Gene3D G3DSA:1.20.120.430 7 56 0.043 T 28-03-2018 CNX65_RS34610 bc33a7f078f7857adaf9ce156cb841fd 610 SUPERFAMILY SSF52540 42 275 4.91E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14550 5fc5efd957279acd9641be0667716c1f 684 Pfam PF13676 TIR domain 9 115 2.2E-13 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14550 5fc5efd957279acd9641be0667716c1f 684 SUPERFAMILY SSF52200 9 124 4.71E-6 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14550 5fc5efd957279acd9641be0667716c1f 684 SUPERFAMILY SSF52540 184 280 1.12E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14550 5fc5efd957279acd9641be0667716c1f 684 Gene3D G3DSA:3.40.50.10140 7 161 7.8E-14 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS14550 5fc5efd957279acd9641be0667716c1f 684 Gene3D G3DSA:3.40.50.300 190 466 2.7E-7 T 28-03-2018 CNX65_RS34490 bf0488a06cbb4b791101731293e80f5b 299 Gene3D G3DSA:1.10.1660.10 1 105 3.4E-21 T 28-03-2018 CNX65_RS34490 bf0488a06cbb4b791101731293e80f5b 299 Pfam PF13411 MerR HTH family regulatory protein 4 72 9.3E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS34490 bf0488a06cbb4b791101731293e80f5b 299 SUPERFAMILY SSF46955 4 106 2.01E-20 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS34490 bf0488a06cbb4b791101731293e80f5b 299 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 40 60 1.0E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS34490 bf0488a06cbb4b791101731293e80f5b 299 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 1.0E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS34490 bf0488a06cbb4b791101731293e80f5b 299 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 1.0E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS34490 bf0488a06cbb4b791101731293e80f5b 299 SMART SM00422 4 73 2.4E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17865 b12fe6bb2045d0c61058d7f9c23a79da 321 SUPERFAMILY SSF101898 206 319 8.89E-15 T 28-03-2018 CNX65_RS17865 b12fe6bb2045d0c61058d7f9c23a79da 321 SUPERFAMILY SSF101898 55 135 8.89E-15 T 28-03-2018 CNX65_RS17865 b12fe6bb2045d0c61058d7f9c23a79da 321 Gene3D G3DSA:2.120.10.30 33 158 0.12 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS17865 b12fe6bb2045d0c61058d7f9c23a79da 321 Gene3D G3DSA:2.130.10.10 176 321 7.0E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 SUPERFAMILY SSF51445 92 403 5.27E-93 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 Gene3D G3DSA:3.30.379.10 23 82 1.0E-10 T 28-03-2018 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 SUPERFAMILY SSF55545 2 89 8.52E-14 T 28-03-2018 IPR029018 Chitobiase/beta-hexosaminidase domain 2-like Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 Gene3D G3DSA:3.20.20.80 83 432 5.1E-107 T 28-03-2018 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 Pfam PF02838 Glycosyl hydrolase family 20, domain 2 27 87 2.7E-9 T 28-03-2018 IPR015882 Beta-hexosaminidase, bacteial type, N-terminal KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 270 401 1.2E-22 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 Pfam PF00728 Glycosyl hydrolase family 20, catalytic domain 92 265 3.1E-61 T 28-03-2018 IPR015883 Glycoside hydrolase family 20, catalytic domain GO:0004553|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 PRINTS PR00738 Glycosyl hydrolase family 20 signature 85 102 4.8E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 PRINTS PR00738 Glycosyl hydrolase family 20 signature 383 400 4.8E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 PRINTS PR00738 Glycosyl hydrolase family 20 signature 230 248 4.8E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 PRINTS PR00738 Glycosyl hydrolase family 20 signature 43 63 4.8E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 PRINTS PR00738 Glycosyl hydrolase family 20 signature 114 135 4.8E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 PRINTS PR00738 Glycosyl hydrolase family 20 signature 185 202 4.8E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS02280 46afea7654509134c8fde2a2c10e29f5 447 PRINTS PR00738 Glycosyl hydrolase family 20 signature 252 265 4.8E-35 T 28-03-2018 IPR025705 Beta-hexosaminidase GO:0004563|GO:0005975 KEGG: 00511+3.2.1.52|KEGG: 00513+3.2.1.52|KEGG: 00520+3.2.1.52|KEGG: 00531+3.2.1.52|KEGG: 00603+3.2.1.52|KEGG: 00604+3.2.1.52|MetaCyc: PWY-6902|MetaCyc: PWY-7822|Reactome: R-HSA-1660662|Reactome: R-HSA-2022857|Reactome: R-HSA-2024101|Reactome: R-HSA-2160916 CNX65_RS26255 092325fb801a5354096e14ec34dd0ca4 205 Gene3D G3DSA:1.10.530.10 14 116 1.5E-31 T 28-03-2018 CNX65_RS26255 092325fb801a5354096e14ec34dd0ca4 205 SUPERFAMILY SSF54106 158 204 8.89E-6 T 28-03-2018 IPR018392 LysM domain CNX65_RS26255 092325fb801a5354096e14ec34dd0ca4 205 Pfam PF06737 Transglycosylase-like domain 39 111 2.6E-33 T 28-03-2018 IPR010618 Transglycosylase-like CNX65_RS26255 092325fb801a5354096e14ec34dd0ca4 205 SMART SM00257 157 205 7.8E-7 T 28-03-2018 IPR018392 LysM domain CNX65_RS26255 092325fb801a5354096e14ec34dd0ca4 205 SUPERFAMILY SSF53955 39 113 1.42E-31 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS26255 092325fb801a5354096e14ec34dd0ca4 205 Pfam PF01476 LysM domain 158 204 4.3E-8 T 28-03-2018 IPR018392 LysM domain CNX65_RS26255 092325fb801a5354096e14ec34dd0ca4 205 Gene3D G3DSA:3.10.350.10 152 205 1.8E-13 T 28-03-2018 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 Pfam PF00145 C-5 cytosine-specific DNA methylase 1 343 2.8E-58 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 ProSitePatterns PS00094 C-5 cytosine-specific DNA methylases active site. 62 74 - T 28-03-2018 IPR018117 DNA methylase, C-5 cytosine-specific, active site KEGG: 00270+2.1.1.37|Reactome: R-HSA-212300|Reactome: R-HSA-5334118 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 141 154 3.4E-6 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 100 114 3.4E-6 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 1 178 3.3E-42 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 Gene3D G3DSA:3.40.50.150 1 191 1.3E-54 T 28-03-2018 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 Gene3D G3DSA:3.90.120.10 224 331 1.5E-11 T 28-03-2018 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 ProSitePatterns PS00095 C-5 cytosine-specific DNA methylases C-terminal signature. 325 343 - T 28-03-2018 IPR031303 DNA methylase, C-5 cytosine-specific, conserved site KEGG: 00270+2.1.1.37 CNX65_RS05270 162cb6b2cd2059c59426d945698490ce 361 SUPERFAMILY SSF53335 2 343 7.8E-83 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS13790 6a2cbc87417b82a56761240cb71d5265 323 Gene3D G3DSA:1.10.3470.10 1 323 3.3E-50 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS13790 6a2cbc87417b82a56761240cb71d5265 323 Pfam PF01032 FecCD transport family 16 318 2.8E-68 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS13790 6a2cbc87417b82a56761240cb71d5265 323 SUPERFAMILY SSF81345 3 318 9.94E-62 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 Pfam PF00270 DEAD/DEAH box helicase 195 258 4.5E-7 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 Gene3D G3DSA:3.40.50.300 576 849 4.1E-10 T 28-03-2018 CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 SMART SM00490 566 643 7.5E-4 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 SMART SM00487 172 449 4.8E-13 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 Pfam PF00271 Helicase conserved C-terminal domain 599 642 4.5E-6 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 Gene3D G3DSA:3.40.50.300 157 452 2.5E-20 T 28-03-2018 CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 SUPERFAMILY SSF52540 336 431 5.05E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 SUPERFAMILY SSF52540 566 644 5.05E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 SUPERFAMILY SSF52540 195 251 5.05E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04825 d57a6dc074a63b25a07f5dc0b2b97adc 1495 SUPERFAMILY SSF52540 469 525 5.05E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03690 27ce4804f5cafb1736c5733e6e4976d3 515 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 323 501 6.9E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03690 27ce4804f5cafb1736c5733e6e4976d3 515 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 59 229 2.0E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03690 27ce4804f5cafb1736c5733e6e4976d3 515 SUPERFAMILY SSF161098 4 225 6.65E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03690 27ce4804f5cafb1736c5733e6e4976d3 515 SUPERFAMILY SSF161098 252 507 1.12E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03690 27ce4804f5cafb1736c5733e6e4976d3 515 Gene3D G3DSA:1.10.3720.10 1 236 2.6E-27 T 28-03-2018 CNX65_RS03690 27ce4804f5cafb1736c5733e6e4976d3 515 Gene3D G3DSA:1.10.3720.10 252 510 2.4E-31 T 28-03-2018 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SUPERFAMILY SSF56801 1841 1927 2.35E-8 T 28-03-2018 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:3.40.47.10 46 313 1.4E-80 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SUPERFAMILY SSF47336 762 856 1.83E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:3.40.47.10 316 475 4.0E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:3.90.1150.10 1285 1398 8.8E-8 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:3.20.20.30 1435 1773 1.2E-62 T 28-03-2018 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SUPERFAMILY SSF53901 50 422 1.63E-90 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:3.90.1150.10 958 1147 3.6E-34 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SMART SM00823 Phosphopantetheine attachment site 769 841 2.7E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 427 540 8.1E-14 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:3.40.640.10 1148 1284 4.2E-31 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SUPERFAMILY SSF53383 999 1397 5.62E-87 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Pfam PF00202 Aminotransferase class-III 1002 1326 1.5E-50 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 55 301 3.2E-79 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 TIGRFAM TIGR04020 seco_metab_LLM: natural product biosynthesis luciferase-like monooxygenase domain 1431 1767 2.2E-132 T 28-03-2018 IPR024011 Natural product biosynthesis luciferase-like monooxygenase domain CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 1201 1237 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Pfam PF00501 AMP-binding enzyme 1859 1914 4.6E-5 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 309 424 1.3E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:3.40.50.980 1836 1974 1.1E-8 T 28-03-2018 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Pfam PF00296 Luciferase-like monooxygenase 1443 1745 6.0E-45 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Gene3D G3DSA:1.10.1200.10 756 852 4.8E-16 T 28-03-2018 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SMART SM00825 Beta-ketoacyl synthase 56 477 4.0E-169 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SUPERFAMILY SSF51679 1440 1765 2.09E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 SMART SM01294 770 837 4.4E-4 T 28-03-2018 CNX65_RS17040 4e98f67c24638e45dc7a5d649d358fe8 2016 Pfam PF00550 Phosphopantetheine attachment site 771 837 3.4E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15815 4dda843c73adaec3fe4b03ba76ed6932 412 SMART SM00331 179 400 7.0E-26 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS15815 4dda843c73adaec3fe4b03ba76ed6932 412 SUPERFAMILY SSF81606 191 398 1.31E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS15815 4dda843c73adaec3fe4b03ba76ed6932 412 Gene3D G3DSA:3.60.40.10 151 403 4.5E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS15815 4dda843c73adaec3fe4b03ba76ed6932 412 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 206 400 8.5E-45 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS29830 15a7b7b3fced42b2755b4e3fa27e9a65 248 Gene3D G3DSA:2.160.10.10 112 247 1.0E-27 T 28-03-2018 CNX65_RS29830 15a7b7b3fced42b2755b4e3fa27e9a65 248 SUPERFAMILY SSF51161 34 219 2.11E-31 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS29830 15a7b7b3fced42b2755b4e3fa27e9a65 248 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 163 197 1.5E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS29830 15a7b7b3fced42b2755b4e3fa27e9a65 248 Gene3D G3DSA:2.160.10.10 48 111 0.0013 T 28-03-2018 CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 ProSitePatterns PS00519 AsnC-type HTH domain signature. 23 49 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 Pfam PF01037 Lrp/AsnC ligand binding domain 88 139 1.1E-9 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 32 51 6.6E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 21 32 6.6E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 5 21 6.6E-17 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 Gene3D G3DSA:1.10.10.10 6 55 1.2E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 Gene3D G3DSA:3.30.70.920 56 144 2.8E-14 T 28-03-2018 CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 Pfam PF13404 AsnC-type helix-turn-helix domain 5 46 2.9E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 SUPERFAMILY SSF46785 5 64 1.15E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 SUPERFAMILY SSF54909 67 141 9.12E-11 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS01265 3b28996e306acd9ec9a39d21371c981c 149 SMART SM00344 5 112 1.4E-33 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS18725 6449f9dc47d228327039902888c9b181 339 Gene3D G3DSA:3.60.40.10 150 339 1.4E-18 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18725 6449f9dc47d228327039902888c9b181 339 Pfam PF13581 Histidine kinase-like ATPase domain 22 137 7.2E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18725 6449f9dc47d228327039902888c9b181 339 SUPERFAMILY SSF81606 160 338 8.63E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18725 6449f9dc47d228327039902888c9b181 339 Gene3D G3DSA:3.30.565.10 10 149 2.6E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18725 6449f9dc47d228327039902888c9b181 339 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 177 311 2.9E-14 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18725 6449f9dc47d228327039902888c9b181 339 SMART SM00331 151 339 2.1E-10 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18725 6449f9dc47d228327039902888c9b181 339 SUPERFAMILY SSF55874 30 137 9.51E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 Gene3D G3DSA:3.40.50.2300 1 127 1.7E-36 T 28-03-2018 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 SMART SM00421 143 200 5.6E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 3.9E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 SUPERFAMILY SSF52172 1 127 9.25E-31 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 SUPERFAMILY SSF46894 137 205 6.46E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 Gene3D G3DSA:1.10.10.10 128 205 2.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 SMART SM00448 1 109 2.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 3.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 3.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 3.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11320 8762e72067e8f83ab53f4a92f215cd8c 208 Pfam PF00072 Response regulator receiver domain 1 109 3.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS31040 6d86a1f64ac926a8d37fc481d564c90b 223 Pfam PF01636 Phosphotransferase enzyme family 114 185 1.0E-7 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS31040 6d86a1f64ac926a8d37fc481d564c90b 223 Pfam PF01636 Phosphotransferase enzyme family 34 102 5.2E-8 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS31040 6d86a1f64ac926a8d37fc481d564c90b 223 SUPERFAMILY SSF56112 22 202 9.55E-26 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS31040 6d86a1f64ac926a8d37fc481d564c90b 223 Gene3D G3DSA:3.30.200.20 16 80 4.0E-4 T 28-03-2018 CNX65_RS31040 6d86a1f64ac926a8d37fc481d564c90b 223 Gene3D G3DSA:1.10.510.10 81 189 2.6E-14 T 28-03-2018 CNX65_RS07560 312f535157d7dfa60f7021977f24aade 225 SMART SM00448 1 112 2.3E-36 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS07560 312f535157d7dfa60f7021977f24aade 225 SMART SM00862 145 217 1.9E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS07560 312f535157d7dfa60f7021977f24aade 225 Gene3D G3DSA:1.10.10.10 119 222 2.3E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07560 312f535157d7dfa60f7021977f24aade 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 9.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS07560 312f535157d7dfa60f7021977f24aade 225 SUPERFAMILY SSF52172 2 172 1.71E-36 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS07560 312f535157d7dfa60f7021977f24aade 225 Gene3D G3DSA:3.40.50.2300 1 118 2.7E-32 T 28-03-2018 CNX65_RS07560 312f535157d7dfa60f7021977f24aade 225 Pfam PF00072 Response regulator receiver domain 3 113 6.3E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 Gene3D G3DSA:3.30.9.10 111 216 5.0E-17 T 28-03-2018 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 Gene3D G3DSA:3.30.9.10 217 353 3.3E-42 T 28-03-2018 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 409 532 1.8E-33 T 28-03-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 Pfam PF01266 FAD dependent oxidoreductase 33 381 6.2E-49 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 Gene3D G3DSA:3.40.50.720 30 87 1.2E-8 T 28-03-2018 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 SUPERFAMILY SSF51905 30 331 2.59E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 37 54 - T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 61 73 1.4E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 376 388 1.4E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 107 119 1.4E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 346 352 1.4E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 45 55 1.4E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS31465 03f5b86d50f64774706f57581f516310 579 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 32 44 1.4E-31 T 28-03-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-163560 CNX65_RS17600 a76a5ff533817323c502ea5c4020e562 597 Gene3D G3DSA:3.40.190.10 185 290 4.2E-21 T 28-03-2018 CNX65_RS17600 a76a5ff533817323c502ea5c4020e562 597 SUPERFAMILY SSF53850 28 534 3.44E-121 T 28-03-2018 CNX65_RS17600 a76a5ff533817323c502ea5c4020e562 597 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 74 447 3.2E-83 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS17600 a76a5ff533817323c502ea5c4020e562 597 Gene3D G3DSA:3.10.105.10 291 514 5.4E-52 T 28-03-2018 CNX65_RS17600 a76a5ff533817323c502ea5c4020e562 597 Gene3D G3DSA:3.90.76.10 41 184 3.0E-34 T 28-03-2018 CNX65_RS17600 a76a5ff533817323c502ea5c4020e562 597 PIRSF PIRSF002741 5 538 4.2E-95 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS01570 4b4d46b7534c5e8e6dfb420831f833ab 172 SMART SM00347 37 137 6.6E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS01570 4b4d46b7534c5e8e6dfb420831f833ab 172 Pfam PF01047 MarR family 48 101 3.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS01570 4b4d46b7534c5e8e6dfb420831f833ab 172 Gene3D G3DSA:1.10.10.10 2 157 5.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01570 4b4d46b7534c5e8e6dfb420831f833ab 172 SUPERFAMILY SSF46785 29 154 5.15E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01570 4b4d46b7534c5e8e6dfb420831f833ab 172 ProSitePatterns PS01117 MarR-type HTH domain signature. 76 110 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CNX65_RS24910 12bfcfc3dceb80ad8b491bb597671a55 343 Gene3D G3DSA:1.10.3470.10 13 343 3.3E-62 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS24910 12bfcfc3dceb80ad8b491bb597671a55 343 Pfam PF01032 FecCD transport family 29 334 1.1E-77 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS24910 12bfcfc3dceb80ad8b491bb597671a55 343 SUPERFAMILY SSF81345 12 333 1.96E-67 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS29785 b4c20d5f77b0e82735ca1179b824bb8f 280 SUPERFAMILY SSF82549 4 277 1.28E-60 T 28-03-2018 CNX65_RS29785 b4c20d5f77b0e82735ca1179b824bb8f 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 5 278 2.1E-61 T 28-03-2018 IPR003797 DegV CNX65_RS29785 b4c20d5f77b0e82735ca1179b824bb8f 280 Gene3D G3DSA:3.40.50.10170 1 153 1.8E-38 T 28-03-2018 CNX65_RS29785 b4c20d5f77b0e82735ca1179b824bb8f 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 5 277 5.0E-65 T 28-03-2018 IPR003797 DegV CNX65_RS29785 b4c20d5f77b0e82735ca1179b824bb8f 280 Gene3D G3DSA:3.30.1180.10 154 278 2.2E-33 T 28-03-2018 CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 Gene3D G3DSA:2.60.40.10 461 558 7.6E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 401 411 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 200 211 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 SUPERFAMILY SSF52743 180 457 1.22E-76 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 PRINTS PR00723 Subtilisin serine protease family (S8) signature 195 214 5.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 PRINTS PR00723 Subtilisin serine protease family (S8) signature 231 244 5.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 PRINTS PR00723 Subtilisin serine protease family (S8) signature 400 416 5.4E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 Gene3D G3DSA:2.60.40.650 961 1055 4.6E-4 T 28-03-2018 CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 Gene3D G3DSA:3.40.50.200 163 460 1.4E-83 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07720 0d22eb80fe20f0fa44304e5822f70828 1056 Pfam PF00082 Subtilase family 195 450 8.8E-54 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS11540 fea1eaf208d12e907460df20543f2aa3 204 SUPERFAMILY SSF81301 13 201 1.1E-53 T 28-03-2018 CNX65_RS11540 fea1eaf208d12e907460df20543f2aa3 204 Pfam PF04607 Region found in RelA / SpoT proteins 48 169 1.8E-32 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CNX65_RS11540 fea1eaf208d12e907460df20543f2aa3 204 SMART SM00954 48 171 6.9E-43 T 28-03-2018 IPR007685 RelA/SpoT GO:0015969 CNX65_RS11540 fea1eaf208d12e907460df20543f2aa3 204 Gene3D G3DSA:3.30.460.10 7 152 2.3E-33 T 28-03-2018 CNX65_RS11540 fea1eaf208d12e907460df20543f2aa3 204 Gene3D G3DSA:1.10.287.860 154 202 4.4E-17 T 28-03-2018 CNX65_RS03360 9cffb71a6dbdbc50590a20250bc9701c 320 Gene3D G3DSA:3.30.420.40 1 121 6.1E-46 T 28-03-2018 CNX65_RS03360 9cffb71a6dbdbc50590a20250bc9701c 320 Gene3D G3DSA:3.30.420.150 122 316 4.0E-53 T 28-03-2018 CNX65_RS03360 9cffb71a6dbdbc50590a20250bc9701c 320 SUPERFAMILY SSF53067 133 316 1.62E-35 T 28-03-2018 CNX65_RS03360 9cffb71a6dbdbc50590a20250bc9701c 320 SUPERFAMILY SSF53067 3 127 4.14E-32 T 28-03-2018 CNX65_RS03360 9cffb71a6dbdbc50590a20250bc9701c 320 Pfam PF02541 Ppx/GppA phosphatase family 23 312 2.8E-70 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CNX65_RS17735 5dee1f0a52e59229a4e1640fe68280ba 374 Pfam PF05139 Erythromycin esterase 42 370 2.4E-50 T 28-03-2018 IPR007815 Erythromycin esterase GO:0046677 CNX65_RS17735 5dee1f0a52e59229a4e1640fe68280ba 374 Gene3D G3DSA:3.40.1660.10 242 373 0.38 T 28-03-2018 CNX65_RS17735 5dee1f0a52e59229a4e1640fe68280ba 374 Gene3D G3DSA:1.20.1440.30 119 241 1.3E-10 T 28-03-2018 CNX65_RS17735 5dee1f0a52e59229a4e1640fe68280ba 374 Gene3D G3DSA:3.30.1870.10 44 118 1.8E-12 T 28-03-2018 CNX65_RS17735 5dee1f0a52e59229a4e1640fe68280ba 374 SUPERFAMILY SSF159501 10 371 1.92E-62 T 28-03-2018 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 SUPERFAMILY SSF46894 137 208 9.18E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 Pfam PF00072 Response regulator receiver domain 5 116 1.0E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 SMART SM00448 3 116 2.3E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 Gene3D G3DSA:3.40.50.2300 2 134 3.2E-30 T 28-03-2018 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 Gene3D G3DSA:1.10.10.10 135 210 2.9E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 SMART SM00421 148 205 1.3E-23 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 205 5.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 SUPERFAMILY SSF52172 3 132 9.68E-28 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 5.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 5.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09530 11855c0f2fbd793f66c2381c6df15977 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 5.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS04045 f8b6bc9895dad9f50b8c05f829d22855 285 SMART SM00481 3 67 1.0E-12 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CNX65_RS04045 f8b6bc9895dad9f50b8c05f829d22855 285 Gene3D G3DSA:3.20.20.140 1 266 9.5E-47 T 28-03-2018 CNX65_RS04045 f8b6bc9895dad9f50b8c05f829d22855 285 SUPERFAMILY SSF89550 2 85 5.62E-41 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CNX65_RS04045 f8b6bc9895dad9f50b8c05f829d22855 285 SUPERFAMILY SSF89550 167 266 5.62E-41 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CNX65_RS04045 f8b6bc9895dad9f50b8c05f829d22855 285 Pfam PF02811 PHP domain 4 173 1.4E-10 T 28-03-2018 IPR004013 PHP domain GO:0003824 CNX65_RS23160 e88af4ff786a4d184b9e991b6aed5ffb 684 Gene3D G3DSA:1.10.10.10 484 531 4.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23160 e88af4ff786a4d184b9e991b6aed5ffb 684 Gene3D G3DSA:1.10.10.10 535 626 0.065 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23160 e88af4ff786a4d184b9e991b6aed5ffb 684 Gene3D G3DSA:3.40.50.300 52 201 7.8E-11 T 28-03-2018 CNX65_RS23160 e88af4ff786a4d184b9e991b6aed5ffb 684 SUPERFAMILY SSF52540 59 262 2.3E-17 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26745 a78d282e4e6adda3d24f56f50c315ffa 303 Pfam PF09362 Domain of unknown function (DUF1996) 65 256 1.9E-23 T 28-03-2018 IPR018535 Domain of unknown function DUF1996 CNX65_RS15110 e43e4eae740bb8e79ddcdd84b6f30db2 200 SUPERFAMILY SSF47413 8 75 6.76E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS15110 e43e4eae740bb8e79ddcdd84b6f30db2 200 Gene3D G3DSA:2.60.120.10 69 197 1.4E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS15110 e43e4eae740bb8e79ddcdd84b6f30db2 200 SMART SM00530 15 70 5.9E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS15110 e43e4eae740bb8e79ddcdd84b6f30db2 200 Pfam PF13560 Helix-turn-helix domain 12 70 1.3E-12 T 28-03-2018 CNX65_RS15110 e43e4eae740bb8e79ddcdd84b6f30db2 200 SUPERFAMILY SSF51182 66 176 6.06E-22 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS15110 e43e4eae740bb8e79ddcdd84b6f30db2 200 Pfam PF07883 Cupin domain 118 177 5.6E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CNX65_RS15110 e43e4eae740bb8e79ddcdd84b6f30db2 200 Gene3D G3DSA:1.10.260.40 4 68 2.6E-17 T 28-03-2018 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 Pfam PF08447 PAS fold 97 158 9.2E-7 T 28-03-2018 IPR013655 PAS fold-3 GO:0005515 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 97 188 1.4E-5 T 28-03-2018 IPR000014 PAS domain CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 Gene3D G3DSA:3.30.450.20 55 182 3.3E-12 T 28-03-2018 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 SUPERFAMILY SSF47384 311 392 1.1E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 Gene3D G3DSA:3.30.565.10 386 546 5.5E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 473 487 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 506 524 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 PRINTS PR00344 Bacterial sensor protein C-terminal signature 530 543 1.1E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 SUPERFAMILY SSF55874 380 544 1.31E-45 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 SUPERFAMILY SSF55785 179 303 6.28E-5 T 28-03-2018 IPR000014 PAS domain CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 436 543 7.0E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 SUPERFAMILY SSF55785 82 188 2.44E-10 T 28-03-2018 IPR000014 PAS domain CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 Gene3D G3DSA:3.30.450.20 183 320 4.0E-10 T 28-03-2018 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 SMART SM00388 325 391 4.7E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 SMART SM00387 436 546 2.1E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 Gene3D G3DSA:1.10.287.130 321 385 5.2E-17 T 28-03-2018 CNX65_RS11760 edfbe520ce0cae860fb45036bb51638b 549 Pfam PF00512 His Kinase A (phospho-acceptor) domain 326 390 6.7E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 Gene3D G3DSA:3.90.1150.10 313 413 1.4E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 Pfam PF00155 Aminotransferase class I and II 46 403 1.5E-72 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 213 236 8.2E-11 T 28-03-2018 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 177 201 8.2E-11 T 28-03-2018 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 244 268 8.2E-11 T 28-03-2018 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 130 151 8.2E-11 T 28-03-2018 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 Gene3D G3DSA:3.40.640.10 60 312 1.7E-64 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 SUPERFAMILY SSF53383 17 411 1.3E-112 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS32600 d41b64ee160639dde9769cb148e71993 413 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 250 263 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CNX65_RS14210 6c124ee24c37e80cdd7960907f6c4882 322 SUPERFAMILY SSF51735 11 303 6.03E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14210 6c124ee24c37e80cdd7960907f6c4882 322 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS14210 6c124ee24c37e80cdd7960907f6c4882 322 Gene3D G3DSA:3.40.50.720 5 174 1.0E-30 T 28-03-2018 CNX65_RS14210 6c124ee24c37e80cdd7960907f6c4882 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 13 225 7.4E-42 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS14210 6c124ee24c37e80cdd7960907f6c4882 322 Gene3D G3DSA:3.90.25.10 175 306 5.7E-28 T 28-03-2018 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 Gene3D G3DSA:1.10.10.60 235 272 1.0E-9 T 28-03-2018 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 SUPERFAMILY SSF46689 221 268 1.34E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 Pfam PF01965 DJ-1/PfpI family 11 179 8.1E-14 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 271 313 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 Gene3D G3DSA:3.40.50.880 5 234 2.5E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 Pfam PF12833 Helix-turn-helix domain 240 318 3.3E-19 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 SUPERFAMILY SSF46689 271 321 1.29E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 Gene3D G3DSA:1.10.10.60 273 327 6.0E-9 T 28-03-2018 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 SMART SM00342 234 317 3.1E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16705 462e99ac7f020b05fd259fdffb6beeb0 332 SUPERFAMILY SSF52317 10 200 3.36E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS00745 208cf530a2c36fe16ee18f4782c0b73c 227 Pfam PF01738 Dienelactone hydrolase family 20 225 7.3E-28 T 28-03-2018 IPR002925 Dienelactone hydrolase GO:0016787 CNX65_RS00745 208cf530a2c36fe16ee18f4782c0b73c 227 Gene3D G3DSA:3.40.50.1820 4 227 1.7E-22 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS00745 208cf530a2c36fe16ee18f4782c0b73c 227 SUPERFAMILY SSF53474 5 226 2.75E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02295 8c894f6b4cf0532eb82408de85663fb4 312 Pfam PF13378 Enolase C-terminal domain-like 79 281 1.9E-36 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS02295 8c894f6b4cf0532eb82408de85663fb4 312 Gene3D G3DSA:3.30.390.10 1 82 2.4E-41 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS02295 8c894f6b4cf0532eb82408de85663fb4 312 Gene3D G3DSA:3.20.20.120 83 282 9.5E-47 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS02295 8c894f6b4cf0532eb82408de85663fb4 312 SUPERFAMILY SSF51604 63 281 1.7E-51 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS02295 8c894f6b4cf0532eb82408de85663fb4 312 SMART SM00922 73 173 5.8E-21 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CNX65_RS13305 adab05d61b0a8880b912e9b65757bf1d 444 SUPERFAMILY SSF51679 4 443 4.45E-93 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS13305 adab05d61b0a8880b912e9b65757bf1d 444 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 7 441 2.5E-109 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CNX65_RS13305 adab05d61b0a8880b912e9b65757bf1d 444 Gene3D G3DSA:3.20.20.30 3 444 4.5E-75 T 28-03-2018 CNX65_RS13305 adab05d61b0a8880b912e9b65757bf1d 444 PIRSF PIRSF000337 3 444 2.1E-103 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CNX65_RS13305 adab05d61b0a8880b912e9b65757bf1d 444 Pfam PF00296 Luciferase-like monooxygenase 21 395 5.1E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS28090 47b6ded1381e2849f2b8e325126637e1 229 Gene3D G3DSA:1.10.10.10 151 208 9.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28090 47b6ded1381e2849f2b8e325126637e1 229 SUPERFAMILY SSF55811 9 137 9.75E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS28090 47b6ded1381e2849f2b8e325126637e1 229 Pfam PF00293 NUDIX domain 10 117 2.0E-7 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS28090 47b6ded1381e2849f2b8e325126637e1 229 Gene3D G3DSA:3.90.79.10 4 150 2.3E-27 T 28-03-2018 CNX65_RS28090 47b6ded1381e2849f2b8e325126637e1 229 SUPERFAMILY SSF46785 141 212 1.96E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 366 3.8E-24 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 SUPERFAMILY SSF56645 16 207 3.01E-32 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 PIRSF PIRSF016578 1 394 9.2E-113 T 28-03-2018 CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 Gene3D G3DSA:2.40.110.10 115 208 3.6E-13 T 28-03-2018 CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 Gene3D G3DSA:1.10.540.10 6 114 1.8E-12 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 25 100 4.9E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 Gene3D G3DSA:1.20.140.10 211 393 4.1E-9 T 28-03-2018 CNX65_RS20455 0088541f1952b7756ff230d1255009bd 394 SUPERFAMILY SSF47203 232 369 2.47E-9 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS15190 a10911a05ee3c19e66d83a7540af4af5 441 Pfam PF01699 Sodium/calcium exchanger protein 47 212 1.5E-11 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CNX65_RS15190 a10911a05ee3c19e66d83a7540af4af5 441 Pfam PF01699 Sodium/calcium exchanger protein 244 415 1.7E-5 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CNX65_RS19415 6bf49b7cd331294c5cb1a9b7f2026f05 447 Pfam PF06965 Na+/H+ antiporter 1 40 415 3.3E-130 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CNX65_RS19415 6bf49b7cd331294c5cb1a9b7f2026f05 447 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 42 415 7.1E-95 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CNX65_RS19415 6bf49b7cd331294c5cb1a9b7f2026f05 447 Gene3D G3DSA:1.20.1530.10 36 421 1.1E-137 T 28-03-2018 IPR023171 Na/H antiporter domain CNX65_RS19415 6bf49b7cd331294c5cb1a9b7f2026f05 447 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 38 424 20.289 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 Gene3D G3DSA:1.25.40.10 207 312 3.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 Gene3D G3DSA:1.25.40.10 116 206 6.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 SUPERFAMILY SSF48452 20 229 2.95E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 SMART SM00028 41 74 85.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 SMART SM00028 117 150 16.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 SMART SM00028 157 190 68.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 SMART SM00028 81 114 82.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 Pfam PF12770 CHAT domain 626 853 1.6E-36 T 28-03-2018 IPR024983 CHAT domain CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 Pfam PF13424 Tetratricopeptide repeat 41 111 7.4E-8 T 28-03-2018 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 Pfam PF13424 Tetratricopeptide repeat 119 189 3.1E-10 T 28-03-2018 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 Gene3D G3DSA:3.40.50.1460 675 861 1.9E-9 T 28-03-2018 CNX65_RS26940 5ffb3d24878f54ead2d3ca532617a40c 873 Gene3D G3DSA:1.25.40.10 5 115 3.9E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05595 d4c931ea15fbc1f9e5e0e7566560f3b5 311 SUPERFAMILY SSF52540 5 228 4.89E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05595 d4c931ea15fbc1f9e5e0e7566560f3b5 311 Gene3D G3DSA:3.40.50.300 2 274 7.4E-61 T 28-03-2018 CNX65_RS05595 d4c931ea15fbc1f9e5e0e7566560f3b5 311 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS05595 d4c931ea15fbc1f9e5e0e7566560f3b5 311 Pfam PF00005 ABC transporter 21 164 3.1E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS05595 d4c931ea15fbc1f9e5e0e7566560f3b5 311 SMART SM00382 30 213 1.4E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05595 d4c931ea15fbc1f9e5e0e7566560f3b5 311 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 13 306 1.0E-96 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CNX65_RS18840 0f5248a21179635508a603fd0ab255c3 132 Gene3D G3DSA:1.10.1660.10 1 118 5.0E-21 T 28-03-2018 CNX65_RS18840 0f5248a21179635508a603fd0ab255c3 132 SUPERFAMILY SSF46955 7 109 4.58E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS18840 0f5248a21179635508a603fd0ab255c3 132 Pfam PF13411 MerR HTH family regulatory protein 7 74 2.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18840 0f5248a21179635508a603fd0ab255c3 132 SMART SM00422 6 75 2.0E-21 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18840 0f5248a21179635508a603fd0ab255c3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 18 31 1.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18840 0f5248a21179635508a603fd0ab255c3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 7 18 1.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS18840 0f5248a21179635508a603fd0ab255c3 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 1.2E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 Gene3D G3DSA:1.10.287.130 232 296 2.2E-10 T 28-03-2018 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 SUPERFAMILY SSF47384 228 308 4.12E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 SMART SM00388 244 308 1.7E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 SMART SM00387 351 461 1.6E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 245 307 2.8E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 388 402 1.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 439 1.4E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 Gene3D G3DSA:3.30.450.20 30 158 5.4E-5 T 28-03-2018 CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 Gene3D G3DSA:3.30.565.10 297 461 6.7E-29 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 SUPERFAMILY SSF55874 298 459 4.98E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07165 7cf0e70daa72906520492bad6ccdf58f 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 454 3.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 Gene3D G3DSA:3.40.50.1700 368 687 1.9E-64 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 Gene3D G3DSA:3.20.20.300 37 367 9.9E-77 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 Pfam PF14310 Fibronectin type III-like domain 716 784 2.8E-15 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 SUPERFAMILY SSF51445 33 373 2.32E-71 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 SUPERFAMILY SSF50405 436 504 1.06E-8 T 28-03-2018 IPR008999 Actin cross-linking CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 375 687 3.4E-55 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 PRINTS PR00133 Glycosyl hydrolase family 3 signature 184 200 1.5E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 PRINTS PR00133 Glycosyl hydrolase family 3 signature 96 115 1.5E-6 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 SMART SM01217 716 784 4.7E-21 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 80 336 4.3E-35 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 SUPERFAMILY SSF52279 375 437 2.88E-44 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 SUPERFAMILY SSF52279 545 690 2.88E-44 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS11065 da7896e0ab6b48b07dfd6560fcf05645 875 Gene3D G3DSA:2.60.40.10 688 798 7.4E-27 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS13965 f21c39f8f410b306964ff99e11fe8d85 144 SUPERFAMILY SSF55781 3 140 9.16E-12 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS13965 f21c39f8f410b306964ff99e11fe8d85 144 Gene3D G3DSA:3.30.450.40 2 144 1.6E-13 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS13965 f21c39f8f410b306964ff99e11fe8d85 144 Pfam PF13185 GAF domain 10 132 6.7E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS28825 d437b5bd47a355b926d532e4362be98d 644 SUPERFAMILY SSF52151 382 465 4.45E-10 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS28825 d437b5bd47a355b926d532e4362be98d 644 SUPERFAMILY SSF52151 291 339 4.45E-10 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS28825 d437b5bd47a355b926d532e4362be98d 644 Gene3D G3DSA:3.40.1090.10 5 440 1.3E-26 T 28-03-2018 CNX65_RS28825 d437b5bd47a355b926d532e4362be98d 644 Pfam PF01734 Patatin-like phospholipase 18 79 4.5E-6 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CNX65_RS28825 d437b5bd47a355b926d532e4362be98d 644 Pfam PF01734 Patatin-like phospholipase 381 433 1.2E-7 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CNX65_RS33400 341d705f819f790679d0541c7e9b12c3 418 Pfam PF04286 Protein of unknown function (DUF445) 54 416 1.4E-103 T 28-03-2018 IPR007383 Protein of unknown function DUF445 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 278 289 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 99 110 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 353 364 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 197 219 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 295 322 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 160 175 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 143 159 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 344 353 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 PRINTS PR00359 B-class P450 signature 323 338 1.4E-48 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 Pfam PF00067 Cytochrome P450 190 372 1.2E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 346 355 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 Gene3D G3DSA:1.10.630.10 12 403 5.2E-69 T 28-03-2018 CNX65_RS18215 c399fc609e6523036721ea272ae0966c 419 SUPERFAMILY SSF48264 19 401 2.88E-86 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 TIGRFAM TIGR02094 more_P_ylases: alpha-glucan phosphorylases 113 697 5.5E-228 T 28-03-2018 IPR011834 Alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 Pfam PF11897 Protein of unknown function (DUF3417) 13 125 1.7E-30 T 28-03-2018 IPR024517 Glycogen phosphorylase, domain of unknown function DUF3417 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 Pfam PF00343 Carbohydrate phosphorylase 130 175 3.6E-5 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 Pfam PF00343 Carbohydrate phosphorylase 280 609 9.3E-15 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 Gene3D G3DSA:3.40.50.2000 258 430 1.7E-52 T 28-03-2018 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 Gene3D G3DSA:3.40.50.2000 115 257 5.8E-33 T 28-03-2018 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 PIRSF PIRSF000460 1 783 1.8E-250 T 28-03-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 Gene3D G3DSA:3.40.50.2000 431 720 8.6E-77 T 28-03-2018 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 SUPERFAMILY SSF53756 4 730 4.19E-194 T 28-03-2018 CNX65_RS29880 2aabf84075ed739a8eb7e1de458067d1 835 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 587 599 - T 28-03-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 CNX65_RS26265 68819f9c85739ae750be362990d62008 259 Pfam PF04397 LytTr DNA-binding domain 160 251 6.4E-22 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CNX65_RS26265 68819f9c85739ae750be362990d62008 259 Pfam PF00072 Response regulator receiver domain 3 117 1.1E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS26265 68819f9c85739ae750be362990d62008 259 SUPERFAMILY SSF52172 1 128 2.28E-28 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS26265 68819f9c85739ae750be362990d62008 259 Gene3D G3DSA:2.40.50.40 149 217 4.2E-16 T 28-03-2018 CNX65_RS26265 68819f9c85739ae750be362990d62008 259 SMART SM00448 1 117 4.2E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS26265 68819f9c85739ae750be362990d62008 259 Gene3D G3DSA:3.40.50.2300 1 148 5.5E-28 T 28-03-2018 CNX65_RS26265 68819f9c85739ae750be362990d62008 259 SMART SM00850 157 252 3.9E-27 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CNX65_RS01235 9537332a64741aaf5f9b5e686b85bef4 390 TIGRFAM TIGR00773 NhaA: Na+/H+ antiporter NhaA 16 378 9.0E-103 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CNX65_RS01235 9537332a64741aaf5f9b5e686b85bef4 390 Hamap MF_01844 Na(+)/H(+) antiporter NhaA [nhaA]. 12 387 20.744 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CNX65_RS01235 9537332a64741aaf5f9b5e686b85bef4 390 Pfam PF06965 Na+/H+ antiporter 1 14 379 2.4E-128 T 28-03-2018 IPR004670 Na+/H+ antiporter NhaA GO:0006814|GO:0006885|GO:0016021 CNX65_RS01235 9537332a64741aaf5f9b5e686b85bef4 390 Gene3D G3DSA:1.20.1530.10 10 385 1.1E-130 T 28-03-2018 IPR023171 Na/H antiporter domain CNX65_RS05000 779fc1593cff0409da46f6eb434da681 450 SUPERFAMILY SSF53448 51 324 2.72E-30 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS05000 779fc1593cff0409da46f6eb434da681 450 Gene3D G3DSA:3.90.550.10 32 339 3.7E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS05000 779fc1593cff0409da46f6eb434da681 450 Pfam PF13641 Glycosyltransferase like family 2 51 299 9.2E-25 T 28-03-2018 CNX65_RS08655 fd1dc7ee886532a063450bb076d85f39 371 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 10 366 6.8E-115 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS08655 fd1dc7ee886532a063450bb076d85f39 371 SUPERFAMILY SSF53383 2 368 9.65E-105 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS08655 fd1dc7ee886532a063450bb076d85f39 371 Gene3D G3DSA:3.40.640.10 2 243 7.1E-51 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS08655 fd1dc7ee886532a063450bb076d85f39 371 PIRSF PIRSF000390 1 371 1.1E-107 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS08655 fd1dc7ee886532a063450bb076d85f39 371 Gene3D G3DSA:3.90.1150.10 244 371 1.9E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS25610 fb7a54a8fb6e4e893deae7c10721b023 147 Gene3D G3DSA:3.90.1010.10 1 140 3.6E-53 T 28-03-2018 CNX65_RS25610 fb7a54a8fb6e4e893deae7c10721b023 147 SUPERFAMILY SSF82649 2 141 1.44E-46 T 28-03-2018 CNX65_RS25610 fb7a54a8fb6e4e893deae7c10721b023 147 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 3 139 9.6E-49 T 28-03-2018 CNX65_RS25610 fb7a54a8fb6e4e893deae7c10721b023 147 Pfam PF01592 NifU-like N terminal domain 6 127 5.1E-28 T 28-03-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 CNX65_RS05700 b08db7d154bde9a67dca35fd82288105 155 Gene3D G3DSA:3.40.1400.10 1 154 2.4E-58 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS05700 b08db7d154bde9a67dca35fd82288105 155 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 147 2.9E-56 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS05700 b08db7d154bde9a67dca35fd82288105 155 PIRSF PIRSF005384 1 149 3.2E-50 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS05700 b08db7d154bde9a67dca35fd82288105 155 SUPERFAMILY SSF89623 2 151 8.63E-53 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS05700 b08db7d154bde9a67dca35fd82288105 155 Pfam PF02502 Ribose/Galactose Isomerase 3 140 7.8E-48 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS05700 b08db7d154bde9a67dca35fd82288105 155 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 1 148 7.1E-69 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CNX65_RS12915 3ff171fa723d0b8d96daa864ddf93707 165 Gene3D G3DSA:3.30.530.20 2 164 6.2E-25 T 28-03-2018 IPR023393 START-like domain CNX65_RS12915 3ff171fa723d0b8d96daa864ddf93707 165 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 26 139 2.6E-11 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS12915 3ff171fa723d0b8d96daa864ddf93707 165 SUPERFAMILY SSF55961 2 162 1.73E-35 T 28-03-2018 CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.8E-32 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 34 - T 28-03-2018 IPR019844 Cold-shock conserved site CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 SMART SM00357 3 67 4.2E-31 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 SUPERFAMILY SSF50249 1 66 1.27E-25 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 PRINTS PR00050 Cold shock protein signature 4 19 2.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 PRINTS PR00050 Cold shock protein signature 25 34 2.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 PRINTS PR00050 Cold shock protein signature 40 58 2.3E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 PIRSF PIRSF002599 1 67 4.3E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CNX65_RS33530 baf24663a80bd3b5dc0a77d15d800a54 67 Gene3D G3DSA:2.40.50.140 1 67 8.6E-30 T 28-03-2018 CNX65_RS01670 25d6aba58a015ac08ac1fcdbda1a675d 296 Gene3D G3DSA:3.30.1300.10 190 296 3.1E-34 T 28-03-2018 CNX65_RS01670 25d6aba58a015ac08ac1fcdbda1a675d 296 SUPERFAMILY SSF52374 12 291 8.91E-101 T 28-03-2018 CNX65_RS01670 25d6aba58a015ac08ac1fcdbda1a675d 296 Gene3D G3DSA:3.40.50.620 5 189 5.4E-74 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS01670 25d6aba58a015ac08ac1fcdbda1a675d 296 Pfam PF02569 Pantoate-beta-alanine ligase 17 287 9.7E-94 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CNX65_RS01670 25d6aba58a015ac08ac1fcdbda1a675d 296 Hamap MF_00158 Pantothenate synthetase [panC]. 16 289 37.662 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CNX65_RS01670 25d6aba58a015ac08ac1fcdbda1a675d 296 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 19 288 6.5E-82 T 28-03-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 SMART SM00382 181 375 7.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 Hamap MF_01884 Transcription termination factor Rho [rho]. 53 430 149.094 T 28-03-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 Gene3D G3DSA:2.40.50.140 34 140 1.1E-18 T 28-03-2018 CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 Gene3D G3DSA:3.40.50.300 143 380 8.9E-43 T 28-03-2018 CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 SUPERFAMILY SSF50249 68 139 1.88E-9 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 SUPERFAMILY SSF52540 132 381 3.02E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 Pfam PF07497 Rho termination factor, RNA-binding domain 69 139 1.3E-16 T 28-03-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 CNX65_RS20320 d44c9df886dbb0b87c0907d5562c757a 439 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 171 374 6.0E-20 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS11890 37ceca704bde303d126fd8a46ba1f8f5 149 Pfam PF03748 Flagellar basal body-associated protein FliL 61 149 1.8E-13 T 28-03-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 CNX65_RS01250 fb1f4806c213457cd6def17a898f2d44 240 SUPERFAMILY SSF140931 141 229 8.37E-5 T 28-03-2018 IPR003812 Fido domain CNX65_RS01250 fb1f4806c213457cd6def17a898f2d44 240 Gene3D G3DSA:1.10.3290.10 15 240 4.5E-12 T 28-03-2018 IPR003812 Fido domain CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 ProSitePatterns PS00356 LacI-type HTH domain signature. 10 28 - T 28-03-2018 CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 7.3E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 Gene3D G3DSA:1.10.260.40 8 60 4.3E-23 T 28-03-2018 CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 SUPERFAMILY SSF53822 64 314 4.71E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 Gene3D G3DSA:3.40.50.2300 177 310 5.4E-38 T 28-03-2018 CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 Pfam PF13377 Periplasmic binding protein-like domain 171 325 1.7E-35 T 28-03-2018 CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 SMART SM00354 7 77 2.3E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 SUPERFAMILY SSF47413 7 65 1.69E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS25350 1e11198364cdd0adb2d35c70593dd94f 326 Gene3D G3DSA:3.40.50.2300 61 176 4.0E-31 T 28-03-2018 CNX65_RS20205 76c6e34e14561eae352557e8fa44b056 422 Gene3D G3DSA:1.20.91.10 250 335 1.0E-17 T 28-03-2018 CNX65_RS20205 76c6e34e14561eae352557e8fa44b056 422 Pfam PF00999 Sodium/hydrogen exchanger family 15 397 3.3E-52 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CNX65_RS21060 2a6511745db25c12df659c0f45cf0065 180 Pfam PF11695 Domain of unknown function (DUF3291) 5 163 1.3E-45 T 28-03-2018 IPR021708 Domain of unknown function DUF3291 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Gene3D G3DSA:2.160.20.60 1236 1506 2.1E-110 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Gene3D G3DSA:3.20.20.70 797 1233 5.1E-157 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 SUPERFAMILY SSF51395 453 1217 2.61E-260 T 28-03-2018 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 SUPERFAMILY SSF56235 22 440 4.56E-144 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Pfam PF00310 Glutamine amidotransferases class-II 22 438 1.8E-173 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Gene3D G3DSA:3.60.20.10 22 447 1.3E-165 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 SUPERFAMILY SSF69336 1230 1492 4.45E-89 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Pfam PF04898 Glutamate synthase central domain 465 752 1.5E-107 T 28-03-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Gene3D G3DSA:3.20.20.70 448 796 6.1E-95 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Pfam PF01645 Conserved region in glutamate synthase 817 1181 5.8E-152 T 28-03-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 CNX65_RS27900 aa309e4a819a3a17e2d4128cfe3c6798 1512 Pfam PF01493 GXGXG motif 1262 1438 8.7E-77 T 28-03-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS06205 2606b2192cf9f893c31f2048a11dbefe 414 Gene3D G3DSA:3.40.50.1110 203 410 1.3E-27 T 28-03-2018 CNX65_RS06205 2606b2192cf9f893c31f2048a11dbefe 414 SUPERFAMILY SSF52266 214 413 5.04E-44 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS06205 2606b2192cf9f893c31f2048a11dbefe 414 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 217 403 3.6E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS01255 99718e34289521bcce7f09933cb80931 373 Pfam PF00266 Aminotransferase class-V 139 316 1.7E-19 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS01255 99718e34289521bcce7f09933cb80931 373 Gene3D G3DSA:3.40.640.10 30 275 1.3E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS01255 99718e34289521bcce7f09933cb80931 373 Gene3D G3DSA:3.90.1150.10 276 373 1.4E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS01255 99718e34289521bcce7f09933cb80931 373 Hamap MF_01970 Kynureninase [kynU]. 2 373 32.643 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CNX65_RS01255 99718e34289521bcce7f09933cb80931 373 SUPERFAMILY SSF53383 3 373 3.06E-85 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS01255 99718e34289521bcce7f09933cb80931 373 TIGRFAM TIGR01814 kynureninase: kynureninase 2 372 9.7E-79 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CNX65_RS01255 99718e34289521bcce7f09933cb80931 373 PIRSF PIRSF038800 1 373 3.6E-129 T 28-03-2018 IPR010111 Kynureninase GO:0005737|GO:0006569|GO:0009435|GO:0030170|GO:0030429 KEGG: 00380+3.7.1.3|MetaCyc: PWY-5651|MetaCyc: PWY-6309|Reactome: R-HSA-71240 CNX65_RS12925 73fc20841c0a1bbe60d92b99cbc34ffd 370 Gene3D G3DSA:3.40.50.2000 199 354 5.2E-37 T 28-03-2018 CNX65_RS12925 73fc20841c0a1bbe60d92b99cbc34ffd 370 SUPERFAMILY SSF53756 2 370 9.77E-68 T 28-03-2018 CNX65_RS12925 73fc20841c0a1bbe60d92b99cbc34ffd 370 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 203 347 1.0E-15 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CNX65_RS12925 73fc20841c0a1bbe60d92b99cbc34ffd 370 Gene3D G3DSA:3.40.50.2000 1 198 9.0E-25 T 28-03-2018 CNX65_RS12925 73fc20841c0a1bbe60d92b99cbc34ffd 370 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 203 341 2.9E-34 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CNX65_RS09910 8a7377b1c6a2ff55ec5be4293e2033f0 229 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 136 185 3.8E-14 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS09910 8a7377b1c6a2ff55ec5be4293e2033f0 229 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 65 112 1.2E-4 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS09910 8a7377b1c6a2ff55ec5be4293e2033f0 229 Gene3D G3DSA:1.10.1780.10 54 120 4.5E-8 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS09910 8a7377b1c6a2ff55ec5be4293e2033f0 229 Gene3D G3DSA:1.10.1780.10 121 221 2.3E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS09910 8a7377b1c6a2ff55ec5be4293e2033f0 229 SUPERFAMILY SSF81923 57 181 4.32E-19 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 SMART SM00448 4 117 1.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 SMART SM00421 151 208 1.5E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 SUPERFAMILY SSF46894 146 213 8.16E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 Gene3D G3DSA:3.40.50.2300 3 128 5.9E-29 T 28-03-2018 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 Gene3D G3DSA:1.10.10.10 129 215 8.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 7.9E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 Pfam PF00072 Response regulator receiver domain 6 118 2.8E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 5.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 5.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 5.0E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34865 7a564c20af636b26c716cab7e3ed69fa 219 SUPERFAMILY SSF52172 1 123 1.02E-28 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS32295 f4c1549f7d840b86d6adcd273ebbea21 196 Pfam PF01196 Ribosomal protein L17 20 116 2.1E-35 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32295 f4c1549f7d840b86d6adcd273ebbea21 196 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 5 116 25.501 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32295 f4c1549f7d840b86d6adcd273ebbea21 196 Gene3D G3DSA:3.90.1030.10 1 117 7.6E-45 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32295 f4c1549f7d840b86d6adcd273ebbea21 196 ProSitePatterns PS01167 Ribosomal protein L17 signature. 34 56 - T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32295 f4c1549f7d840b86d6adcd273ebbea21 196 TIGRFAM TIGR00059 L17: ribosomal protein bL17 9 116 8.4E-40 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32295 f4c1549f7d840b86d6adcd273ebbea21 196 SUPERFAMILY SSF64263 1 117 5.49E-46 T 28-03-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 ProSitePatterns PS00211 ABC transporters family signature. 429 443 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 SMART SM00382 314 506 1.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 SMART SM00382 46 240 4.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 243 280 0.029 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 508 534 8.5E-4 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 ProSitePatterns PS00211 ABC transporters family signature. 163 177 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 SUPERFAMILY SSF52540 282 533 1.28E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 Pfam PF00005 ABC transporter 38 191 1.2E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 Pfam PF00005 ABC transporter 306 457 1.2E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 Gene3D G3DSA:3.40.50.300 288 536 4.6E-69 T 28-03-2018 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 Gene3D G3DSA:3.40.50.300 19 287 1.2E-64 T 28-03-2018 CNX65_RS21650 6eb94967ba050966935c198369ddeea5 537 SUPERFAMILY SSF52540 21 262 4.53E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 SUPERFAMILY SSF48371 484 534 1.64E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 SUPERFAMILY SSF48371 48 165 1.64E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 SUPERFAMILY SSF48371 240 312 1.64E-10 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 SUPERFAMILY SSF48371 224 313 5.95E-12 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 Gene3D G3DSA:1.25.40.70 21 119 0.037 T 28-03-2018 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 Gene3D G3DSA:1.25.40.70 124 259 0.0082 T 28-03-2018 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 Gene3D G3DSA:1.25.40.70 260 316 9.9E-4 T 28-03-2018 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 SMART SM00567 E-Z type HEAT repeats 284 313 0.55 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 SMART SM00567 E-Z type HEAT repeats 139 167 110.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 SMART SM00567 E-Z type HEAT repeats 226 249 340.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS19950 d59da13cb27ee65681844ca2a6e456e9 590 Gene3D G3DSA:1.25.10.20 326 587 1.1E-4 T 28-03-2018 CNX65_RS02565 6ddce95b8532b43b5c9ab2ae69b078c1 238 TIGRFAM TIGR00101 ureG: urease accessory protein UreG 38 227 1.2E-81 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CNX65_RS02565 6ddce95b8532b43b5c9ab2ae69b078c1 238 PIRSF PIRSF005624 24 238 4.1E-43 T 28-03-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 CNX65_RS02565 6ddce95b8532b43b5c9ab2ae69b078c1 238 Gene3D G3DSA:3.40.50.300 37 237 9.1E-18 T 28-03-2018 CNX65_RS02565 6ddce95b8532b43b5c9ab2ae69b078c1 238 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 40 210 3.1E-32 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CNX65_RS02565 6ddce95b8532b43b5c9ab2ae69b078c1 238 Hamap MF_01389 Urease accessory protein UreG [ureG]. 36 234 42.805 T 28-03-2018 IPR004400 Urease accessory protein UreG GO:0003924|GO:0006807|GO:0016151 CNX65_RS02565 6ddce95b8532b43b5c9ab2ae69b078c1 238 SUPERFAMILY SSF52540 24 229 1.02E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02655 bb954eb6ce9565810936c93c206127fd 290 Gene3D G3DSA:2.70.98.10 1 287 1.1E-61 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS02655 bb954eb6ce9565810936c93c206127fd 290 SUPERFAMILY SSF74650 4 284 1.07E-56 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CNX65_RS02655 bb954eb6ce9565810936c93c206127fd 290 Pfam PF01263 Aldose 1-epimerase 2 283 1.4E-40 T 28-03-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 CNX65_RS28855 a02aaa839774d87d1185df7b85b039eb 304 SUPERFAMILY SSF53850 89 300 2.8E-38 T 28-03-2018 CNX65_RS28855 a02aaa839774d87d1185df7b85b039eb 304 SUPERFAMILY SSF46785 1 112 5.71E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28855 a02aaa839774d87d1185df7b85b039eb 304 Gene3D G3DSA:3.40.190.10 89 185 4.0E-24 T 28-03-2018 CNX65_RS28855 a02aaa839774d87d1185df7b85b039eb 304 Gene3D G3DSA:3.40.190.10 186 269 1.3E-20 T 28-03-2018 CNX65_RS28855 a02aaa839774d87d1185df7b85b039eb 304 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 62 1.9E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS28855 a02aaa839774d87d1185df7b85b039eb 304 Gene3D G3DSA:1.10.10.10 1 84 3.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28855 a02aaa839774d87d1185df7b85b039eb 304 Pfam PF03466 LysR substrate binding domain 88 296 2.3E-41 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS02540 c59967da02bb0a8a5f47e3861e84ec16 429 SUPERFAMILY SSF103473 20 408 6.15E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS02540 c59967da02bb0a8a5f47e3861e84ec16 429 Pfam PF05977 Transmembrane secretion effector 14 399 3.5E-32 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS02540 c59967da02bb0a8a5f47e3861e84ec16 429 Gene3D G3DSA:1.20.1250.20 13 212 2.3E-18 T 28-03-2018 CNX65_RS02540 c59967da02bb0a8a5f47e3861e84ec16 429 Gene3D G3DSA:1.20.1250.20 213 416 2.4E-12 T 28-03-2018 CNX65_RS23215 c681c13b8d64fb4c2e6cccb8d8c18b2c 453 Gene3D G3DSA:3.40.50.920 179 451 1.1E-24 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS23215 c681c13b8d64fb4c2e6cccb8d8c18b2c 453 SUPERFAMILY SSF52922 324 426 4.71E-22 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS23215 c681c13b8d64fb4c2e6cccb8d8c18b2c 453 Pfam PF02780 Transketolase, C-terminal domain 328 434 6.1E-21 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS23215 c681c13b8d64fb4c2e6cccb8d8c18b2c 453 Gene3D G3DSA:3.40.50.970 99 167 1.3E-5 T 28-03-2018 CNX65_RS23215 c681c13b8d64fb4c2e6cccb8d8c18b2c 453 SUPERFAMILY SSF52518 40 159 7.85E-9 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS26475 8a02af6f89aeed6e7c289d1928b81e63 329 Pfam PF16670 Phosphoinositide phospholipase C, Ca2+-dependent 96 208 2.3E-11 T 28-03-2018 IPR032075 Phosphoinositide phospholipase C, Ca2+-dependent CNX65_RS26475 8a02af6f89aeed6e7c289d1928b81e63 329 SUPERFAMILY SSF51695 55 196 9.42E-5 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS26475 8a02af6f89aeed6e7c289d1928b81e63 329 Gene3D G3DSA:3.20.20.190 28 234 1.1E-9 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS26025 70c61f3f0e11c6117927f256f2fd2076 142 Gene3D G3DSA:1.10.1740.10 3 75 1.1E-8 T 28-03-2018 CNX65_RS26025 70c61f3f0e11c6117927f256f2fd2076 142 Pfam PF04542 Sigma-70 region 2 15 72 1.1E-5 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26025 70c61f3f0e11c6117927f256f2fd2076 142 Gene3D G3DSA:1.10.10.10 85 142 1.3E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26025 70c61f3f0e11c6117927f256f2fd2076 142 SUPERFAMILY SSF88946 6 73 9.42E-8 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26025 70c61f3f0e11c6117927f256f2fd2076 142 Pfam PF08281 Sigma-70, region 4 87 135 2.0E-6 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26025 70c61f3f0e11c6117927f256f2fd2076 142 SUPERFAMILY SSF88659 87 137 9.94E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS17790 157f0f57f51e9cf7c0ce4d21e5d508d6 323 Gene3D G3DSA:2.20.28.20 2 30 5.9E-4 T 28-03-2018 CNX65_RS17790 157f0f57f51e9cf7c0ce4d21e5d508d6 323 SMART SM00332 66 317 4.8E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS17790 157f0f57f51e9cf7c0ce4d21e5d508d6 323 SUPERFAMILY SSF81606 79 320 4.45E-47 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS17790 157f0f57f51e9cf7c0ce4d21e5d508d6 323 Gene3D G3DSA:3.60.40.10 75 320 2.0E-36 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS17790 157f0f57f51e9cf7c0ce4d21e5d508d6 323 Pfam PF13672 Protein phosphatase 2C 87 286 3.8E-15 T 28-03-2018 CNX65_RS17790 157f0f57f51e9cf7c0ce4d21e5d508d6 323 SMART SM00331 83 319 1.8E-9 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 87 100 7.6E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 156 7.6E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 118 134 7.6E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 76 168 4.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 TIGRFAM TIGR01454 AHBA_synth_RP: AHBA synthesis associated protein 1 205 2.0E-119 T 28-03-2018 IPR006351 3-amino-5-hydroxybenzoic acid synthesis-related CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 Gene3D G3DSA:3.40.50.1000 1 192 4.3E-35 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 Pfam PF13419 Haloacid dehalogenase-like hydrolase 1 173 1.1E-28 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 169 2.9E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS16525 2c7a03eace4226f706626ea0f7abc1ec 212 SUPERFAMILY SSF56784 1 203 1.76E-50 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS30715 37568e93b5f6fd95f1bd037c704b67b3 429 Gene3D G3DSA:3.90.1150.10 291 429 2.5E-49 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS30715 37568e93b5f6fd95f1bd037c704b67b3 429 PIRSF PIRSF001434 1 426 4.3E-130 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS30715 37568e93b5f6fd95f1bd037c704b67b3 429 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 5 422 2.2E-194 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CNX65_RS30715 37568e93b5f6fd95f1bd037c704b67b3 429 Gene3D G3DSA:3.40.640.10 3 289 2.2E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS30715 37568e93b5f6fd95f1bd037c704b67b3 429 SUPERFAMILY SSF53383 3 422 1.79E-121 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS30715 37568e93b5f6fd95f1bd037c704b67b3 429 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 199 213 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS30715 37568e93b5f6fd95f1bd037c704b67b3 429 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 6 422 7.4E-141 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS02080 0a011d025087b3b5a671069ae7056e5b 315 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 300 1.0E-83 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS02080 0a011d025087b3b5a671069ae7056e5b 315 Gene3D G3DSA:3.40.50.1100 101 315 6.8E-53 T 28-03-2018 CNX65_RS02080 0a011d025087b3b5a671069ae7056e5b 315 SUPERFAMILY SSF53686 5 308 8.25E-86 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS02080 0a011d025087b3b5a671069ae7056e5b 315 Gene3D G3DSA:3.40.50.1100 45 100 9.0E-22 T 28-03-2018 CNX65_RS02080 0a011d025087b3b5a671069ae7056e5b 315 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 37 50 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CNX65_RS02080 0a011d025087b3b5a671069ae7056e5b 315 PIRSF PIRSF006278 46 314 7.1E-9 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CNX65_RS10080 81b89782450d47380ac7f9533bb47905 225 Pfam PF08281 Sigma-70, region 4 154 205 5.9E-15 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10080 81b89782450d47380ac7f9533bb47905 225 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 47 207 1.0E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10080 81b89782450d47380ac7f9533bb47905 225 SUPERFAMILY SSF88659 151 209 1.87E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10080 81b89782450d47380ac7f9533bb47905 225 SUPERFAMILY SSF88946 33 132 3.3E-27 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10080 81b89782450d47380ac7f9533bb47905 225 Pfam PF04542 Sigma-70 region 2 51 118 3.1E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS10080 81b89782450d47380ac7f9533bb47905 225 Gene3D G3DSA:1.10.10.10 122 212 7.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10080 81b89782450d47380ac7f9533bb47905 225 Gene3D G3DSA:1.10.1740.10 28 121 6.3E-26 T 28-03-2018 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 Gene3D G3DSA:1.10.10.10 12 96 6.9E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 Gene3D G3DSA:3.40.190.10 191 281 6.8E-16 T 28-03-2018 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 SUPERFAMILY SSF46785 15 99 1.13E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 52 63 1.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 42 1.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 52 1.1E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 SUPERFAMILY SSF53850 104 306 1.32E-29 T 28-03-2018 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 Gene3D G3DSA:3.40.190.10 101 190 7.8E-19 T 28-03-2018 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 16 75 2.7E-24 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15820 d2d4781d17fca8f377dada91457f012b 309 Pfam PF03466 LysR substrate binding domain 100 306 6.0E-30 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS23755 d7af7a4a7ae973fb7db092edf0df0175 353 Gene3D G3DSA:1.10.3470.10 9 348 8.0E-68 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS23755 d7af7a4a7ae973fb7db092edf0df0175 353 SUPERFAMILY SSF81345 14 346 1.02E-73 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS23755 d7af7a4a7ae973fb7db092edf0df0175 353 Pfam PF01032 FecCD transport family 25 345 4.5E-86 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS34160 79ca12c6ec2165748311b4d19f0e260d 155 Pfam PF00583 Acetyltransferase (GNAT) family 28 142 1.7E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS34160 79ca12c6ec2165748311b4d19f0e260d 155 SUPERFAMILY SSF55729 2 145 3.82E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS34160 79ca12c6ec2165748311b4d19f0e260d 155 Gene3D G3DSA:3.40.630.30 1 148 1.7E-26 T 28-03-2018 CNX65_RS16005 24d11a32b0ff26d8c4f2d4d44d970ab6 497 Pfam PF01740 STAS domain 405 483 1.0E-7 T 28-03-2018 IPR002645 STAS domain CNX65_RS16005 24d11a32b0ff26d8c4f2d4d44d970ab6 497 Gene3D G3DSA:3.30.750.24 392 490 1.4E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS16005 24d11a32b0ff26d8c4f2d4d44d970ab6 497 Pfam PF00916 Sulfate permease family 24 150 2.6E-19 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CNX65_RS16005 24d11a32b0ff26d8c4f2d4d44d970ab6 497 Pfam PF00916 Sulfate permease family 171 337 3.2E-26 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CNX65_RS16005 24d11a32b0ff26d8c4f2d4d44d970ab6 497 SUPERFAMILY SSF52091 409 485 1.96E-12 T 28-03-2018 IPR002645 STAS domain CNX65_RS19715 c0ae9cf83761549643fbc1f0f2fbe3cc 192 Gene3D G3DSA:3.30.530.20 1 161 4.8E-31 T 28-03-2018 IPR023393 START-like domain CNX65_RS19715 c0ae9cf83761549643fbc1f0f2fbe3cc 192 SUPERFAMILY SSF55961 4 150 6.52E-38 T 28-03-2018 CNX65_RS19715 c0ae9cf83761549643fbc1f0f2fbe3cc 192 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 16 148 1.8E-24 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 Pfam PF00717 Peptidase S24-like 138 202 3.3E-14 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 174 186 8.4E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 146 157 8.4E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 135 145 8.4E-11 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 TIGRFAM TIGR00498 lexA: repressor LexA 18 218 2.3E-63 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 Pfam PF01726 LexA DNA binding domain 18 78 2.0E-20 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 Gene3D G3DSA:2.10.109.10 104 219 7.8E-25 T 28-03-2018 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 SUPERFAMILY SSF46785 18 82 1.22E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 SUPERFAMILY SSF51306 98 217 3.31E-34 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 Hamap MF_00015 LexA repressor [lexA]. 17 219 30.579 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CNX65_RS19895 1d51db7c175a1524aa78caabe65728fc 219 Gene3D G3DSA:1.10.10.10 12 93 5.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23735 a22770afba34cd9d873e1457b5407248 311 SUPERFAMILY SSF54211 13 173 9.87E-17 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS23735 a22770afba34cd9d873e1457b5407248 311 Gene3D G3DSA:3.30.230.10 32 172 5.9E-12 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS23735 a22770afba34cd9d873e1457b5407248 311 Pfam PF00288 GHMP kinases N terminal domain 99 142 5.6E-6 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 157 2.3E-14 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Gene3D G3DSA:3.30.230.10 532 653 3.2E-36 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SMART SM00889 520 638 2.6E-53 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Pfam PF00679 Elongation factor G C-terminus 640 723 2.0E-19 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Gene3D G3DSA:3.40.50.300 17 319 1.5E-34 T 28-03-2018 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SUPERFAMILY SSF52540 19 199 4.3E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SUPERFAMILY SSF52540 228 313 4.3E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Pfam PF00009 Elongation factor Tu GTP binding domain 22 312 2.6E-33 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SMART SM00382 22 160 0.001 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Gene3D G3DSA:3.30.70.870 441 531 4.7E-17 T 28-03-2018 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Gene3D G3DSA:3.30.70.240 654 731 4.7E-19 T 28-03-2018 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SUPERFAMILY SSF54980 643 723 2.78E-19 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Gene3D G3DSA:2.40.30.10 325 440 4.3E-25 T 28-03-2018 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Pfam PF14492 Elongation Factor G, domain II 445 515 6.5E-20 T 28-03-2018 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SUPERFAMILY SSF54980 445 521 1.4E-14 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SUPERFAMILY SSF50447 336 440 8.84E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SUPERFAMILY SSF50447 280 306 8.84E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SMART SM00838 640 729 5.0E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 SUPERFAMILY SSF54211 520 634 4.3E-34 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Pfam PF03764 Elongation factor G, domain IV 520 634 1.1E-38 T 28-03-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 CNX65_RS10735 3a1ac4cb8cd290f7f6c11ce12c8252d4 737 Pfam PF03144 Elongation factor Tu domain 2 355 431 1.3E-7 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 120 134 8.5E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 203 215 8.5E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 56 71 8.5E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 SUPERFAMILY SSF50494 13 247 2.28E-61 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 66 71 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 Gene3D G3DSA:2.40.10.10 132 249 4.8E-34 T 28-03-2018 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 SMART SM00020 30 249 1.2E-62 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 204 215 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 Pfam PF00089 Trypsin 37 247 1.8E-48 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 Gene3D G3DSA:2.40.10.10 31 60 7.1E-14 T 28-03-2018 CNX65_RS28780 d82dbe9d6b455e39cc8840227f223dcb 249 Gene3D G3DSA:2.40.10.10 61 131 4.1E-19 T 28-03-2018 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 SUPERFAMILY SSF47384 138 209 3.92E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 Pfam PF00512 His Kinase A (phospho-acceptor) domain 146 210 1.7E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 Gene3D G3DSA:3.30.565.10 215 377 3.8E-43 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 SMART SM00387 256 368 3.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 Gene3D G3DSA:1.10.287.130 151 207 2.7E-12 T 28-03-2018 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 Gene3D G3DSA:3.30.450.20 41 150 0.0027 T 28-03-2018 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 SMART SM00388 145 211 4.3E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 SUPERFAMILY SSF55874 201 366 2.1E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 256 367 5.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 321 2.6E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 328 346 2.6E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 352 365 2.6E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS33270 01d9a60668ed08e4e46239f5abd2f1f8 394 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 307 2.6E-20 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS05420 c3db7fbe88db4d121e4aa888565ada9d 215 SUPERFAMILY SSF53335 12 213 2.01E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS05420 c3db7fbe88db4d121e4aa888565ada9d 215 Gene3D G3DSA:3.40.50.150 7 192 7.1E-32 T 28-03-2018 CNX65_RS05420 c3db7fbe88db4d121e4aa888565ada9d 215 Pfam PF13649 Methyltransferase domain 50 141 5.0E-17 T 28-03-2018 CNX65_RS08485 bfd6c0fa94a26593d490c84294526f19 234 SUPERFAMILY SSF56281 4 218 2.84E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS08485 bfd6c0fa94a26593d490c84294526f19 234 Gene3D G3DSA:3.60.15.10 2 222 2.6E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS08485 bfd6c0fa94a26593d490c84294526f19 234 Pfam PF00753 Metallo-beta-lactamase superfamily 9 201 4.0E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS08485 bfd6c0fa94a26593d490c84294526f19 234 SMART SM00849 12 201 6.6E-36 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS06025 d91544ce45964fdf60f7edca6d90173a 256 Gene3D G3DSA:3.10.180.10 138 256 9.9E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS06025 d91544ce45964fdf60f7edca6d90173a 256 Gene3D G3DSA:3.10.180.10 14 136 7.7E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS06025 d91544ce45964fdf60f7edca6d90173a 256 SUPERFAMILY SSF54593 12 163 8.86E-17 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS06025 d91544ce45964fdf60f7edca6d90173a 256 SUPERFAMILY SSF54593 139 250 2.28E-22 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 SMART SM00382 33 221 2.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 SMART SM00382 282 476 1.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 SUPERFAMILY SSF52540 252 484 1.4E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 Pfam PF00005 ABC transporter 26 174 7.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 Pfam PF00005 ABC transporter 275 427 1.5E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 SUPERFAMILY SSF52540 7 236 1.38E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 Gene3D G3DSA:3.40.50.300 259 489 7.7E-40 T 28-03-2018 CNX65_RS15435 61ac8ce626201b13fc51f40f880c88a5 500 Gene3D G3DSA:3.40.50.300 6 246 4.5E-53 T 28-03-2018 CNX65_RS23525 4b485afee1e3b5511b642e7b81e1fe61 388 Gene3D G3DSA:3.30.9.10 85 166 1.1E-12 T 28-03-2018 CNX65_RS23525 4b485afee1e3b5511b642e7b81e1fe61 388 SUPERFAMILY SSF54373 218 320 1.15E-9 T 28-03-2018 CNX65_RS23525 4b485afee1e3b5511b642e7b81e1fe61 388 Pfam PF01266 FAD dependent oxidoreductase 1 356 7.6E-63 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS23525 4b485afee1e3b5511b642e7b81e1fe61 388 SUPERFAMILY SSF51905 1 218 4.27E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23525 4b485afee1e3b5511b642e7b81e1fe61 388 SUPERFAMILY SSF51905 320 378 4.27E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23525 4b485afee1e3b5511b642e7b81e1fe61 388 Gene3D G3DSA:3.50.50.60 305 384 1.7E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23525 4b485afee1e3b5511b642e7b81e1fe61 388 Gene3D G3DSA:3.30.9.10 167 304 9.2E-31 T 28-03-2018 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Pfam PF00501 AMP-binding enzyme 110 358 1.2E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Pfam PF00501 AMP-binding enzyme 14 99 3.8E-16 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Gene3D G3DSA:2.30.38.10 276 351 3.4E-25 T 28-03-2018 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Gene3D G3DSA:3.30.300.30 353 450 4.1E-29 T 28-03-2018 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 ProSitePatterns PS00455 Putative AMP-binding domain signature. 122 133 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Gene3D G3DSA:3.40.50.980 101 127 5.6E-10 T 28-03-2018 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Pfam PF13193 AMP-binding enzyme C-terminal domain 368 442 8.1E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Gene3D G3DSA:3.40.50.980 128 275 8.3E-45 T 28-03-2018 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 SUPERFAMILY SSF56801 11 450 1.26E-130 T 28-03-2018 CNX65_RS32145 5f8bd24f7f324eabef99382f7d6ec7aa 450 Gene3D G3DSA:3.40.50.980 2 100 1.5E-17 T 28-03-2018 CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 Gene3D G3DSA:3.90.1150.10 249 354 3.5E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 218 227 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 Hamap MF_01513 Putative phenylalanine aminotransferase [pat]. 5 355 47.495 T 28-03-2018 IPR024892 Putative phenylalanine aminotransferase CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 4 354 50.531 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 6 351 1.3E-86 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 SUPERFAMILY SSF53383 18 349 1.26E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 Gene3D G3DSA:3.40.640.10 37 248 7.4E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS00740 bad1306a8aaf5146b6cd80fbe87c3517 355 Pfam PF00155 Aminotransferase class I and II 25 347 4.0E-49 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS01225 acafe067e3722edf4724b809ae970421 308 PRINTS PR00412 Epoxide hydrolase signature 107 120 5.2E-23 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS01225 acafe067e3722edf4724b809ae970421 308 PRINTS PR00412 Epoxide hydrolase signature 63 78 5.2E-23 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS01225 acafe067e3722edf4724b809ae970421 308 PRINTS PR00412 Epoxide hydrolase signature 282 304 5.2E-23 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS01225 acafe067e3722edf4724b809ae970421 308 PRINTS PR00412 Epoxide hydrolase signature 43 61 5.2E-23 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS01225 acafe067e3722edf4724b809ae970421 308 Gene3D G3DSA:3.40.50.1820 6 308 6.0E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS01225 acafe067e3722edf4724b809ae970421 308 Pfam PF00561 alpha/beta hydrolase fold 37 290 9.2E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS01225 acafe067e3722edf4724b809ae970421 308 SUPERFAMILY SSF53474 14 307 4.93E-67 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24900 082885e93c59434f5bce2535e8cb9089 724 Gene3D G3DSA:3.40.50.300 168 566 1.6E-32 T 28-03-2018 CNX65_RS24900 082885e93c59434f5bce2535e8cb9089 724 SUPERFAMILY SSF52540 322 398 4.46E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24900 082885e93c59434f5bce2535e8cb9089 724 SUPERFAMILY SSF52540 485 706 4.46E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24900 082885e93c59434f5bce2535e8cb9089 724 SUPERFAMILY SSF52540 163 241 4.46E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24900 082885e93c59434f5bce2535e8cb9089 724 Gene3D G3DSA:3.40.50.300 658 717 4.7E-8 T 28-03-2018 CNX65_RS24900 082885e93c59434f5bce2535e8cb9089 724 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 185 228 7.3E-5 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 SMART SM00345 16 73 8.8E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 Gene3D G3DSA:1.10.10.10 14 72 4.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 SMART SM00866 93 231 2.0E-40 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 Pfam PF07702 UTRA domain 94 230 2.1E-36 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 SUPERFAMILY SSF46785 8 83 5.75E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 Pfam PF00392 Bacterial regulatory proteins, gntR family 26 72 2.8E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 Gene3D G3DSA:3.40.1410.10 73 239 3.3E-47 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 SUPERFAMILY SSF64288 61 238 3.3E-49 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 7.2E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS26175 bf5e558021fb2c9b57f6fb6e271b236c 253 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 7.2E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 4 238 4.8E-50 T 28-03-2018 CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 SUPERFAMILY SSF51735 1 239 1.81E-66 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 Gene3D G3DSA:3.40.50.720 31 240 2.4E-56 T 28-03-2018 CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 Gene3D G3DSA:3.40.50.720 1 30 0.0028 T 28-03-2018 CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 4.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 4.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 146 165 4.1E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 36 53 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14700 6d03de54c7835332f15c3a6fa2858b06 240 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 2.3E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS33475 8f2f156c5f08386a7da2545a301aeea3 180 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 18 42 0.0064 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS33475 8f2f156c5f08386a7da2545a301aeea3 180 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 130 175 3.1E-4 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS33475 8f2f156c5f08386a7da2545a301aeea3 180 Gene3D G3DSA:1.10.1780.10 2 180 1.7E-30 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS33475 8f2f156c5f08386a7da2545a301aeea3 180 SUPERFAMILY SSF81923 4 178 1.59E-15 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS33305 3498fcd8f1d77bd27d002f34bbb17638 417 Hamap MF_01695 D-inositol-3-phosphate glycosyltransferase [mshA]. 2 412 52.785 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CNX65_RS33305 3498fcd8f1d77bd27d002f34bbb17638 417 SUPERFAMILY SSF53756 21 406 4.54E-83 T 28-03-2018 CNX65_RS33305 3498fcd8f1d77bd27d002f34bbb17638 417 TIGRFAM TIGR03449 mycothiol_MshA: D-inositol-3-phosphate glycosyltransferase 3 407 1.8E-198 T 28-03-2018 IPR017814 Mycothiol biosynthesis protein, MshA GO:0008375|GO:0010125 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CNX65_RS33305 3498fcd8f1d77bd27d002f34bbb17638 417 Gene3D G3DSA:3.40.50.2000 18 211 1.7E-23 T 28-03-2018 CNX65_RS33305 3498fcd8f1d77bd27d002f34bbb17638 417 Pfam PF00534 Glycosyl transferases group 1 209 384 1.7E-31 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS33305 3498fcd8f1d77bd27d002f34bbb17638 417 Pfam PF13439 Glycosyltransferase Family 4 22 203 4.8E-34 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS33305 3498fcd8f1d77bd27d002f34bbb17638 417 Gene3D G3DSA:3.40.50.2000 212 388 5.0E-44 T 28-03-2018 CNX65_RS06650 3860199b22c8d7962658f4e561cceaff 269 SUPERFAMILY SSF47413 34 77 8.94E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS06650 3860199b22c8d7962658f4e561cceaff 269 Pfam PF13560 Helix-turn-helix domain 5 84 1.4E-17 T 28-03-2018 CNX65_RS06650 3860199b22c8d7962658f4e561cceaff 269 Gene3D G3DSA:1.10.260.40 1 89 1.1E-15 T 28-03-2018 CNX65_RS06650 3860199b22c8d7962658f4e561cceaff 269 SMART SM00530 9 81 8.5E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS32780 c3a8370f4db2460b0970e0025d00185f 468 Gene3D G3DSA:1.10.443.10 237 453 6.4E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS32780 c3a8370f4db2460b0970e0025d00185f 468 Pfam PF00589 Phage integrase family 265 448 1.6E-12 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS32780 c3a8370f4db2460b0970e0025d00185f 468 Gene3D G3DSA:1.10.150.130 78 236 4.6E-14 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS32780 c3a8370f4db2460b0970e0025d00185f 468 SUPERFAMILY SSF56349 179 298 9.42E-31 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS32780 c3a8370f4db2460b0970e0025d00185f 468 SUPERFAMILY SSF56349 334 450 9.42E-31 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS22560 2898ee99f22e11b7d613a66e28464a76 451 SUPERFAMILY SSF52777 184 425 2.78E-24 T 28-03-2018 CNX65_RS22560 2898ee99f22e11b7d613a66e28464a76 451 Gene3D G3DSA:3.30.559.10 1 204 1.8E-25 T 28-03-2018 CNX65_RS22560 2898ee99f22e11b7d613a66e28464a76 451 Pfam PF00668 Condensation domain 29 321 1.2E-31 T 28-03-2018 IPR001242 Condensation domain CNX65_RS22560 2898ee99f22e11b7d613a66e28464a76 451 SUPERFAMILY SSF52777 8 178 3.34E-29 T 28-03-2018 CNX65_RS01885 2ee832ec8009bcf9076c5d2725d8ab01 284 Gene3D G3DSA:1.10.260.40 1 109 2.6E-16 T 28-03-2018 CNX65_RS01885 2ee832ec8009bcf9076c5d2725d8ab01 284 Pfam PF13560 Helix-turn-helix domain 7 87 9.7E-19 T 28-03-2018 CNX65_RS01885 2ee832ec8009bcf9076c5d2725d8ab01 284 SUPERFAMILY SSF47413 32 80 1.3E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS01885 2ee832ec8009bcf9076c5d2725d8ab01 284 SMART SM00530 11 84 1.3E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS12030 57e36066ab52bd28b48c33cb292176af 127 Pfam PF00072 Response regulator receiver domain 12 118 6.9E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12030 57e36066ab52bd28b48c33cb292176af 127 SUPERFAMILY SSF52172 9 124 4.27E-21 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS12030 57e36066ab52bd28b48c33cb292176af 127 Gene3D G3DSA:3.40.50.2300 1 125 5.3E-20 T 28-03-2018 CNX65_RS12030 57e36066ab52bd28b48c33cb292176af 127 SMART SM00448 10 120 2.0E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS28165 c959ff7b1f5ddb1e001fa0ca1f84b915 229 TIGRFAM TIGR00077 lspA: signal peptidase II 34 186 6.5E-26 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS28165 c959ff7b1f5ddb1e001fa0ca1f84b915 229 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 121 136 6.2E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS28165 c959ff7b1f5ddb1e001fa0ca1f84b915 229 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 79 87 6.2E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS28165 c959ff7b1f5ddb1e001fa0ca1f84b915 229 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 164 180 6.2E-16 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS28165 c959ff7b1f5ddb1e001fa0ca1f84b915 229 Pfam PF01252 Signal peptidase (SPase) II 40 183 2.3E-30 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS28165 c959ff7b1f5ddb1e001fa0ca1f84b915 229 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 32 189 15.054 T 28-03-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 SMART SM00347 20 119 4.8E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 Gene3D G3DSA:1.10.10.10 2 138 8.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 43 59 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 60 75 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 129 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 PRINTS PR00598 Bacterial regulatory protein MarR family signature 79 95 2.2E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 SUPERFAMILY SSF46785 6 132 1.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12040 c203c98955a7339676498bdb3cf0ec74 141 Pfam PF12802 MarR family 25 82 2.0E-13 T 28-03-2018 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 Gene3D G3DSA:3.40.50.1820 46 412 3.5E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 SMART SM00939 377 592 5.0E-46 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 32 44 4.3E-17 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 83 99 4.3E-17 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 560 575 4.3E-17 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 48 58 4.3E-17 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 PRINTS PR00923 Lactococcus X-Pro dipeptidyl-peptidase (S15) family signature 241 257 4.3E-17 T 28-03-2018 IPR008252 Peptidase S15, X-Pro dipeptidyl-peptidase GO:0004177|GO:0006508 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 SUPERFAMILY SSF53474 30 412 1.13E-71 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 62 362 2.4E-63 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 389 589 4.9E-42 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 Gene3D G3DSA:2.60.120.260 413 596 1.1E-39 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS07235 15ed8140890cf527cd2153d2af47133e 607 SUPERFAMILY SSF49785 461 597 4.68E-36 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS15455 403e68a6a76c77b3bd1dd0f45bbf7bd7 392 SUPERFAMILY SSF51658 29 363 7.74E-93 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS15455 403e68a6a76c77b3bd1dd0f45bbf7bd7 392 Pfam PF06134 L-rhamnose isomerase (RhaA) 110 341 2.4E-6 T 28-03-2018 IPR009308 Rhamnose isomerase GO:0008740|GO:0019299|GO:0030145 KEGG: 00051+5.3.1.14 CNX65_RS15455 403e68a6a76c77b3bd1dd0f45bbf7bd7 392 Gene3D G3DSA:3.20.20.150 6 383 4.3E-106 T 28-03-2018 CNX65_RS15455 403e68a6a76c77b3bd1dd0f45bbf7bd7 392 TIGRFAM TIGR02635 RhaI_grampos: L-rhamnose isomerase 9 382 2.0E-190 T 28-03-2018 IPR013457 Rhamnose isomerase-related CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 239 1.1E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 Gene3D G3DSA:1.10.10.10 178 237 2.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 Gene3D G3DSA:1.10.601.10 10 99 6.2E-20 T 28-03-2018 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 SUPERFAMILY SSF88659 104 167 9.59E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 Gene3D G3DSA:1.10.10.10 100 153 5.9E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 SUPERFAMILY SSF88946 10 100 9.81E-27 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 Pfam PF04539 Sigma-70 region 3 114 168 5.0E-8 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 SUPERFAMILY SSF88659 174 241 2.06E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 Pfam PF04542 Sigma-70 region 2 31 100 2.2E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 25 239 3.4E-76 T 28-03-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 Pfam PF04545 Sigma-70, region 4 190 238 2.6E-15 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 PRINTS PR00046 Major sigma-70 factor signature 210 225 1.1E-6 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 PRINTS PR00046 Major sigma-70 factor signature 55 68 1.1E-6 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 PRINTS PR00046 Major sigma-70 factor signature 225 236 1.1E-6 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26880 ca58cc3738c30abe4d5161df60436398 243 PRINTS PR00046 Major sigma-70 factor signature 193 205 1.1E-6 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02965 676dd8f548724126b67f6cca66dc3d85 283 Gene3D G3DSA:1.10.150.130 1 59 9.7E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS02965 676dd8f548724126b67f6cca66dc3d85 283 SUPERFAMILY SSF56349 13 265 4.12E-26 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS02965 676dd8f548724126b67f6cca66dc3d85 283 Gene3D G3DSA:1.10.443.10 63 274 1.2E-26 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS02965 676dd8f548724126b67f6cca66dc3d85 283 Pfam PF00589 Phage integrase family 66 263 1.5E-7 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS20380 989fb59722e95dcaa1ad7778eb159c62 252 SUPERFAMILY SSF52540 30 248 2.08E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS20380 989fb59722e95dcaa1ad7778eb159c62 252 Gene3D G3DSA:3.40.50.300 27 251 4.8E-66 T 28-03-2018 CNX65_RS20380 989fb59722e95dcaa1ad7778eb159c62 252 SMART SM00382 56 243 3.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS20380 989fb59722e95dcaa1ad7778eb159c62 252 Pfam PF00005 ABC transporter 47 195 5.2E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS20380 989fb59722e95dcaa1ad7778eb159c62 252 ProSitePatterns PS00211 ABC transporters family signature. 168 182 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS08045 f7342e0bb08b071173a3de5200586b0b 259 Pfam PF13359 DDE superfamily endonuclease 104 253 3.7E-26 T 28-03-2018 IPR027806 Harbinger transposase-derived nuclease domain CNX65_RS08045 f7342e0bb08b071173a3de5200586b0b 259 Pfam PF13613 Helix-turn-helix of DDE superfamily endonuclease 34 85 1.2E-16 T 28-03-2018 IPR027805 Transposase, Helix-turn-helix domain CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 Pfam PF08029 HisG, C-terminal domain 212 282 5.5E-23 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 SUPERFAMILY SSF54913 215 286 5.0E-19 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 143 164 - T 28-03-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 SUPERFAMILY SSF53850 4 213 3.8E-60 T 28-03-2018 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 Gene3D G3DSA:3.40.190.10 3 111 2.9E-33 T 28-03-2018 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 192 286 2.3E-28 T 28-03-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 Gene3D G3DSA:3.30.70.120 215 279 1.4E-21 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 Pfam PF01634 ATP phosphoribosyltransferase 51 208 4.6E-41 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 Hamap MF_00079 ATP phosphoribosyltransferase [hisG]. 3 287 31.809 T 28-03-2018 IPR020621 ATP phosphoribosyltransferase HisG, long form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 4 185 1.6E-53 T 28-03-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 CNX65_RS11630 b6ad8d8d2a1327a0a5215e2634d4d484 287 Gene3D G3DSA:3.40.190.10 112 174 6.5E-22 T 28-03-2018 CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 SUPERFAMILY SSF46894 125 225 2.83E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 SUPERFAMILY SSF52172 4 125 7.12E-40 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 SMART SM00448 3 113 2.7E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 SMART SM00862 148 224 4.5E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 224 5.0E-21 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 Gene3D G3DSA:3.40.50.2300 2 119 1.5E-35 T 28-03-2018 CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 Pfam PF00072 Response regulator receiver domain 5 114 4.2E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS20370 cdf61e557a5704209905f9f703224cb9 232 Gene3D G3DSA:1.10.10.10 120 230 2.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17450 45c542f09e906035b48e8427ad93ecbf 330 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CNX65_RS17450 45c542f09e906035b48e8427ad93ecbf 330 Pfam PF13280 WYL domain 142 322 5.2E-16 T 28-03-2018 IPR026881 WYL domain CNX65_RS17450 45c542f09e906035b48e8427ad93ecbf 330 Pfam PF08279 HTH domain 7 62 1.6E-12 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CNX65_RS17450 45c542f09e906035b48e8427ad93ecbf 330 SMART SM00420 7 63 0.0013 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS17450 45c542f09e906035b48e8427ad93ecbf 330 SUPERFAMILY SSF46785 6 62 4.63E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17450 45c542f09e906035b48e8427ad93ecbf 330 Gene3D G3DSA:1.10.10.10 1 66 1.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08075 032398f03548131da0110e98f8ba5c9e 376 Pfam PF13692 Glycosyl transferases group 1 197 335 1.6E-25 T 28-03-2018 CNX65_RS08075 032398f03548131da0110e98f8ba5c9e 376 SUPERFAMILY SSF53756 11 371 5.38E-61 T 28-03-2018 CNX65_RS08075 032398f03548131da0110e98f8ba5c9e 376 Pfam PF13439 Glycosyltransferase Family 4 20 177 5.4E-15 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS08075 032398f03548131da0110e98f8ba5c9e 376 Gene3D G3DSA:3.40.50.2000 14 184 1.7E-9 T 28-03-2018 CNX65_RS08075 032398f03548131da0110e98f8ba5c9e 376 Gene3D G3DSA:3.40.50.2000 185 352 4.0E-35 T 28-03-2018 CNX65_RS15750 8999068e9232117755838454312c810d 444 SUPERFAMILY SSF51905 2 181 6.87E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15750 8999068e9232117755838454312c810d 444 SUPERFAMILY SSF51905 273 352 6.87E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15750 8999068e9232117755838454312c810d 444 Gene3D G3DSA:3.50.50.60 1 353 4.6E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15750 8999068e9232117755838454312c810d 444 Pfam PF01494 FAD binding domain 4 346 1.7E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS15750 8999068e9232117755838454312c810d 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.2E-5 T 28-03-2018 CNX65_RS15750 8999068e9232117755838454312c810d 444 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 160 175 2.2E-5 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Gene3D G3DSA:1.25.40.10 688 834 1.1E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Pfam PF03704 Bacterial transcriptional activator domain 98 242 1.4E-39 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SUPERFAMILY SSF46894 2 91 1.05E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SUPERFAMILY SSF48452 94 263 7.59E-35 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 PRINTS PR00364 Disease resistance protein signature 388 402 4.8E-9 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 PRINTS PR00364 Disease resistance protein signature 568 584 4.8E-9 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 PRINTS PR00364 Disease resistance protein signature 312 327 4.8E-9 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 PRINTS PR00364 Disease resistance protein signature 471 485 4.8E-9 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SMART SM01043 98 242 1.5E-45 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Pfam PF00931 NB-ARC domain 311 539 1.7E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SUPERFAMILY SSF52540 275 538 3.14E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Gene3D G3DSA:1.25.40.10 95 271 8.4E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 91 3.9E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Gene3D G3DSA:1.10.101.10 593 687 0.018 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SMART SM00028 734 767 0.0021 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SMART SM00028 774 807 45.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SMART SM00028 854 887 240.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SMART SM00028 814 847 95.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Gene3D G3DSA:3.40.50.300 272 427 1.2E-16 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Pfam PF13424 Tetratricopeptide repeat 737 802 2.5E-9 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Gene3D G3DSA:1.25.40.10 912 1017 0.002 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Gene3D G3DSA:3.30.70.100 835 901 0.03 T 28-03-2018 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 Gene3D G3DSA:1.10.10.10 1 94 4.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SMART SM00862 17 91 1.6E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS26505 ec2cb25cdc3acc6194dfaeccd4a7163e 1026 SUPERFAMILY SSF48452 720 908 3.9E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04775 c1e00c7d3ae7460dafcd4fa4f7dbab14 266 Pfam PF02649 Type I GTP cyclohydrolase folE2 2 251 1.6E-65 T 28-03-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 CNX65_RS04775 c1e00c7d3ae7460dafcd4fa4f7dbab14 266 Gene3D G3DSA:3.10.270.10 1 253 6.7E-73 T 28-03-2018 CNX65_RS32425 6df920a3e078ebb97c0d6cadf31da21a 133 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 13 122 29.783 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32425 6df920a3e078ebb97c0d6cadf31da21a 133 ProSitePatterns PS00464 Ribosomal protein L22 signature. 95 119 - T 28-03-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32425 6df920a3e078ebb97c0d6cadf31da21a 133 SUPERFAMILY SSF54843 11 123 3.27E-42 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32425 6df920a3e078ebb97c0d6cadf31da21a 133 Pfam PF00237 Ribosomal protein L22p/L17e 17 119 6.5E-35 T 28-03-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32425 6df920a3e078ebb97c0d6cadf31da21a 133 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 17 119 2.0E-46 T 28-03-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32425 6df920a3e078ebb97c0d6cadf31da21a 133 Gene3D G3DSA:3.90.470.10 1 133 8.3E-46 T 28-03-2018 CNX65_RS12530 04d0bb013ee1b08f30f60bd8709a4ce6 125 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 12 113 8.2E-18 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS12530 04d0bb013ee1b08f30f60bd8709a4ce6 125 Gene3D G3DSA:3.30.750.24 11 125 2.3E-18 T 28-03-2018 IPR002645 STAS domain CNX65_RS12530 04d0bb013ee1b08f30f60bd8709a4ce6 125 Pfam PF01740 STAS domain 15 117 9.7E-13 T 28-03-2018 IPR002645 STAS domain CNX65_RS12530 04d0bb013ee1b08f30f60bd8709a4ce6 125 SUPERFAMILY SSF52091 13 121 2.35E-17 T 28-03-2018 IPR002645 STAS domain CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 58 73 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 Gene3D G3DSA:3.40.50.300 1 216 6.1E-35 T 28-03-2018 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 PRINTS PR00315 GTP-binding elongation factor signature 65 73 9.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 PRINTS PR00315 GTP-binding elongation factor signature 85 95 9.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 PRINTS PR00315 GTP-binding elongation factor signature 101 112 9.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 PRINTS PR00315 GTP-binding elongation factor signature 138 147 9.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 PRINTS PR00315 GTP-binding elongation factor signature 6 19 9.8E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 SUPERFAMILY SSF52540 3 229 7.59E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 TIGRFAM TIGR02034 CysN: sulfate adenylyltransferase, large subunit 5 414 3.1E-164 T 28-03-2018 IPR011779 Sulphate adenylyltransferase, large subunit GO:0006790 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 SUPERFAMILY SSF50465 311 414 1.94E-26 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 Gene3D G3DSA:2.40.30.10 310 416 1.1E-25 T 28-03-2018 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 SUPERFAMILY SSF50447 217 308 1.56E-19 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 Pfam PF00009 Elongation factor Tu GTP binding domain 5 203 7.2E-38 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06155 7ee89387cddacf85f255a5bf8ab3ddd8 444 Gene3D G3DSA:2.40.30.10 217 309 9.2E-23 T 28-03-2018 CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Pfam PF13519 von Willebrand factor type A domain 227 338 9.3E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Pfam PF07676 WD40-like Beta Propeller Repeat 167 189 4.6E-6 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Pfam PF07676 WD40-like Beta Propeller Repeat 615 629 0.0022 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Pfam PF07676 WD40-like Beta Propeller Repeat 125 141 0.0049 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Pfam PF07676 WD40-like Beta Propeller Repeat 65 81 0.047 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Gene3D G3DSA:2.60.40.10 824 954 9.0E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Gene3D G3DSA:2.60.40.10 506 575 2.1E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 SUPERFAMILY SSF69304 40 196 2.09E-25 T 28-03-2018 CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 SUPERFAMILY SSF69304 580 695 2.09E-25 T 28-03-2018 CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 SUPERFAMILY SSF53300 226 376 5.04E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Gene3D G3DSA:2.130.10.150 21 196 1.7E-17 T 28-03-2018 CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Gene3D G3DSA:2.130.10.150 595 724 1.3E-11 T 28-03-2018 CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Gene3D G3DSA:2.60.40.10 418 505 0.61 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Gene3D G3DSA:3.40.50.410 223 374 7.1E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS26780 df6cb0026dea0223f55e9437de1b0e29 1051 Gene3D G3DSA:2.60.40.10 725 823 5.9E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS04390 654f07bdbbeb25c337b79045b043a463 337 Pfam PF00877 NlpC/P60 family 226 327 3.5E-22 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CNX65_RS04390 654f07bdbbeb25c337b79045b043a463 337 Gene3D G3DSA:2.30.260.10 259 330 1.8E-15 T 28-03-2018 CNX65_RS04390 654f07bdbbeb25c337b79045b043a463 337 SUPERFAMILY SSF54001 211 327 3.14E-32 T 28-03-2018 CNX65_RS04390 654f07bdbbeb25c337b79045b043a463 337 Gene3D G3DSA:3.90.1720.10 15 258 5.4E-14 T 28-03-2018 CNX65_RS00405 1fd808682315bcdaf8eeed0e678ded19 108 Pfam PF06108 Protein of unknown function (DUF952) 5 91 2.7E-18 T 28-03-2018 IPR009297 Protein of unknown function DUF952 CNX65_RS00405 1fd808682315bcdaf8eeed0e678ded19 108 SUPERFAMILY SSF56399 2 105 7.19E-21 T 28-03-2018 CNX65_RS09490 589681b9b7c867b0088e84655f051a6e 328 TIGRFAM TIGR03707 PPK2_P_aer: polyphosphate kinase 2 52 279 1.2E-113 T 28-03-2018 IPR022486 Polyphosphate kinase 2, PA0141 GO:0006793|GO:0008976 CNX65_RS09490 589681b9b7c867b0088e84655f051a6e 328 Pfam PF03976 Polyphosphate kinase 2 (PPK2) 52 278 1.9E-100 T 28-03-2018 IPR022488 Polyphosphate kinase-2-related CNX65_RS09490 589681b9b7c867b0088e84655f051a6e 328 PIRSF PIRSF028756 25 302 7.3E-117 T 28-03-2018 IPR016898 Polyphosphate kinase 2 CNX65_RS09490 589681b9b7c867b0088e84655f051a6e 328 Gene3D G3DSA:3.40.50.300 10 299 2.6E-99 T 28-03-2018 CNX65_RS09490 589681b9b7c867b0088e84655f051a6e 328 SUPERFAMILY SSF52540 82 269 7.67E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25495 69c9d1fcf15aa3923189bea941b0e6b5 245 Gene3D G3DSA:3.40.50.10490 3 240 1.2E-31 T 28-03-2018 CNX65_RS25495 69c9d1fcf15aa3923189bea941b0e6b5 245 SUPERFAMILY SSF53697 16 204 2.22E-19 T 28-03-2018 CNX65_RS25495 69c9d1fcf15aa3923189bea941b0e6b5 245 Pfam PF13580 SIS domain 10 144 2.7E-38 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS11495 0e7f9442055e622fdd0c1b1e7ebfdf5c 376 Gene3D G3DSA:3.90.230.10 146 376 2.6E-68 T 28-03-2018 CNX65_RS11495 0e7f9442055e622fdd0c1b1e7ebfdf5c 376 Pfam PF00557 Metallopeptidase family M24 155 357 6.8E-58 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS11495 0e7f9442055e622fdd0c1b1e7ebfdf5c 376 Pfam PF01321 Creatinase/Prolidase N-terminal domain 16 147 3.8E-12 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CNX65_RS11495 0e7f9442055e622fdd0c1b1e7ebfdf5c 376 Gene3D G3DSA:3.40.350.10 4 144 7.8E-17 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CNX65_RS11495 0e7f9442055e622fdd0c1b1e7ebfdf5c 376 SUPERFAMILY SSF53092 7 145 4.71E-19 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CNX65_RS11495 0e7f9442055e622fdd0c1b1e7ebfdf5c 376 SUPERFAMILY SSF55920 146 374 2.49E-72 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS11495 0e7f9442055e622fdd0c1b1e7ebfdf5c 376 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 304 316 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CNX65_RS30035 3350c6f6933811547fd0f10e30045312 146 Gene3D G3DSA:3.10.180.10 5 146 3.8E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS30035 3350c6f6933811547fd0f10e30045312 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 12 127 8.6E-22 T 28-03-2018 CNX65_RS30035 3350c6f6933811547fd0f10e30045312 146 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 11 142 1.8E-39 T 28-03-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 CNX65_RS30035 3350c6f6933811547fd0f10e30045312 146 SUPERFAMILY SSF54593 8 143 1.09E-33 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS21980 b5909e3a5e626bbb043ac0d51658799d 129 Gene3D G3DSA:1.10.3680.10 5 128 4.8E-8 T 28-03-2018 IPR029024 TerB-like CNX65_RS21980 b5909e3a5e626bbb043ac0d51658799d 129 SUPERFAMILY SSF158682 9 127 4.32E-5 T 28-03-2018 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 SUPERFAMILY SSF51984 5 93 9.02E-14 T 28-03-2018 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 SUPERFAMILY SSF53244 308 448 5.49E-37 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 Gene3D G3DSA:3.90.190.20 312 447 4.8E-35 T 28-03-2018 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 Gene3D G3DSA:3.40.1190.10 97 310 7.0E-49 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 SUPERFAMILY SSF53623 107 304 6.02E-44 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 10 446 1.0E-110 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 Pfam PF08245 Mur ligase middle domain 114 237 2.6E-20 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 Gene3D G3DSA:3.40.50.720 3 93 1.8E-16 T 28-03-2018 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 7 448 31.304 T 28-03-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS28260 f011a9af4425a438de7fbddf56481061 450 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 112 135 - T 28-03-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 4.1E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 2.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 2.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 Pfam PF16925 Bacterial transcriptional repressor C-terminal 84 187 1.8E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 Gene3D G3DSA:1.10.357.10 62 195 2.4E-30 T 28-03-2018 CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 SUPERFAMILY SSF46689 4 85 7.7E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 Gene3D G3DSA:1.10.10.60 8 61 1.1E-20 T 28-03-2018 CNX65_RS22010 136a64e215b0c0f5a679d383b1bd75a3 196 SUPERFAMILY SSF48498 81 190 2.18E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS06210 41fbcba49c7cb0d40729411c39262c24 221 Gene3D G3DSA:3.40.50.1820 9 217 6.0E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS06210 41fbcba49c7cb0d40729411c39262c24 221 SUPERFAMILY SSF53474 13 206 4.15E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS06210 41fbcba49c7cb0d40729411c39262c24 221 Pfam PF00326 Prolyl oligopeptidase family 89 198 6.6E-13 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS04050 e30be1c3cae28306a76636ca2050d787 279 Pfam PF12705 PD-(D/E)XK nuclease superfamily 19 262 8.5E-30 T 28-03-2018 CNX65_RS04050 e30be1c3cae28306a76636ca2050d787 279 Gene3D G3DSA:3.90.320.10 18 203 1.0E-12 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CNX65_RS06330 85190cc7f72a39f3b9b804a41975ccb2 212 Pfam PF02698 DUF218 domain 46 176 5.4E-22 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CNX65_RS06330 85190cc7f72a39f3b9b804a41975ccb2 212 Gene3D G3DSA:3.40.50.620 35 175 6.5E-26 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS21480 b7297b6a5387513a6bbbac792dc0030f 132 Pfam PF03965 Penicillinase repressor 19 128 1.6E-18 T 28-03-2018 IPR005650 BlaI transcriptional regulatory family GO:0003677|GO:0045892 CNX65_RS21480 b7297b6a5387513a6bbbac792dc0030f 132 SUPERFAMILY SSF46785 18 129 4.34E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21480 b7297b6a5387513a6bbbac792dc0030f 132 Gene3D G3DSA:1.10.10.10 21 83 4.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21400 9058eef5e347f20ecf72f9cfdefc37de 145 Gene3D G3DSA:1.10.10.10 2 135 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21400 9058eef5e347f20ecf72f9cfdefc37de 145 SMART SM00347 25 123 5.5E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS21400 9058eef5e347f20ecf72f9cfdefc37de 145 SUPERFAMILY SSF46785 9 134 2.15E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21400 9058eef5e347f20ecf72f9cfdefc37de 145 Pfam PF12802 MarR family 31 86 3.1E-9 T 28-03-2018 CNX65_RS22180 025b108818589f5964a4a2087f2fbe70 281 SUPERFAMILY SSF51735 4 223 4.17E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22180 025b108818589f5964a4a2087f2fbe70 281 Pfam PF13460 NAD(P)H-binding 10 176 2.3E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22180 025b108818589f5964a4a2087f2fbe70 281 Gene3D G3DSA:3.40.50.720 53 277 2.3E-21 T 28-03-2018 CNX65_RS22180 025b108818589f5964a4a2087f2fbe70 281 Gene3D G3DSA:3.40.50.720 1 52 2.7E-7 T 28-03-2018 CNX65_RS15965 dc9098faa42195ea882124ae40541299 378 Gene3D G3DSA:3.40.50.720 10 243 2.2E-32 T 28-03-2018 CNX65_RS15965 dc9098faa42195ea882124ae40541299 378 SUPERFAMILY SSF69572 7 344 2.88E-40 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CNX65_RS15965 dc9098faa42195ea882124ae40541299 378 Gene3D G3DSA:3.40.250.10 273 378 2.1E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS15965 dc9098faa42195ea882124ae40541299 378 Pfam PF00581 Rhodanese-like domain 276 369 3.6E-10 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS15965 dc9098faa42195ea882124ae40541299 378 Pfam PF00899 ThiF family 30 234 3.7E-23 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CNX65_RS15965 dc9098faa42195ea882124ae40541299 378 SMART SM00450 276 373 7.0E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 290 306 1.3E-16 T 28-03-2018 CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 148 163 1.3E-16 T 28-03-2018 CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 275 290 1.3E-16 T 28-03-2018 CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.3E-16 T 28-03-2018 CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 Pfam PF01494 FAD binding domain 1 321 5.2E-30 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 Gene3D G3DSA:3.50.50.60 1 389 1.2E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 SUPERFAMILY SSF51905 1 169 1.99E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21945 3a4a2d7c624e07d4594f6f2ea0f8d05c 417 SUPERFAMILY SSF51905 262 368 1.99E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15185 c7bccf63a7d29455aa16be06e6d85d9a 167 SUPERFAMILY SSF52218 5 147 1.41E-12 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS15185 c7bccf63a7d29455aa16be06e6d85d9a 167 Gene3D G3DSA:3.40.50.360 4 162 1.1E-13 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 60 8.0E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 SMART SM00420 6 58 1.8E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 SUPERFAMILY SSF100950 74 235 9.0E-29 T 28-03-2018 CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 Pfam PF00455 DeoR C terminal sensor domain 75 233 5.6E-49 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 Gene3D G3DSA:3.40.50.1360 74 244 1.0E-38 T 28-03-2018 CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 SUPERFAMILY SSF46785 5 60 3.57E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 SMART SM01134 73 234 3.7E-67 T 28-03-2018 CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.6E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.6E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS05325 490e6ae225ed19a20f54c3eb9906ca49 253 Gene3D G3DSA:1.10.10.10 1 73 1.4E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34925 977a11bc048a871f57b1dda95287be73 626 Pfam PF10101 Predicted membrane protein (DUF2339) 125 519 7.8E-18 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CNX65_RS34925 977a11bc048a871f57b1dda95287be73 626 Pfam PF10101 Predicted membrane protein (DUF2339) 428 613 3.1E-9 T 28-03-2018 IPR019286 Protein of unknown function DUF2339, transmembrane CNX65_RS01370 1f63bffd925ad4742f3bd034a9320e0f 240 Pfam PF12686 Protein of unknown function (DUF3800) 2 120 3.8E-10 T 28-03-2018 IPR024524 Protein of unknown function DUF3800 CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 SUPERFAMILY SSF56645 16 205 3.66E-28 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 Gene3D G3DSA:1.20.140.10 214 390 8.9E-10 T 28-03-2018 CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 SUPERFAMILY SSF47203 232 368 9.84E-10 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 PIRSF PIRSF016578 1 393 6.9E-99 T 28-03-2018 CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 369 1.2E-23 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 Gene3D G3DSA:2.40.110.10 115 208 2.2E-14 T 28-03-2018 CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 Gene3D G3DSA:1.10.540.10 9 112 4.2E-9 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS23415 ff1431553c0779d0caac1043c2c3cf05 393 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 19 96 2.1E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 SMART SM00825 Beta-ketoacyl synthase 38 463 2.3E-192 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 285 1.0E-85 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 SUPERFAMILY SSF53901 438 453 3.34E-95 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 SUPERFAMILY SSF53901 32 406 3.34E-95 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 SMART SM01294 795 862 1.9E-4 T 28-03-2018 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 SUPERFAMILY SSF47336 786 873 7.07E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 Gene3D G3DSA:3.40.47.10 28 297 7.6E-84 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 Gene3D G3DSA:3.40.47.10 300 461 7.0E-56 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 407 3.2E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 Pfam PF00550 Phosphopantetheine attachment site 796 862 1.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 Gene3D G3DSA:1.10.1200.10 788 905 2.1E-18 T 28-03-2018 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 417 550 2.1E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23015 8f2a6fbb416d16070f7fba825457004e 929 SMART SM00823 Phosphopantetheine attachment site 794 866 2.7E-22 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22325 94cdb861c8b844a95e2b42df5d5335a3 381 TIGRFAM TIGR04468 arg_2_3_am_muta: arginine 2,3-aminomutase 19 368 1.9E-194 T 28-03-2018 IPR031015 Arginine 2,3-aminomutase CNX65_RS22325 94cdb861c8b844a95e2b42df5d5335a3 381 SUPERFAMILY SSF102114 113 336 1.44E-29 T 28-03-2018 CNX65_RS22325 94cdb861c8b844a95e2b42df5d5335a3 381 Gene3D G3DSA:3.20.20.70 106 324 3.9E-23 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS22325 94cdb861c8b844a95e2b42df5d5335a3 381 Pfam PF04055 Radical SAM superfamily 124 275 2.3E-8 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS22325 94cdb861c8b844a95e2b42df5d5335a3 381 TIGRFAM TIGR00238 TIGR00238: KamA family protein 15 335 1.5E-97 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CNX65_RS22325 94cdb861c8b844a95e2b42df5d5335a3 381 PIRSF PIRSF004911 2 378 5.1E-149 T 28-03-2018 IPR003739 Lysine-2,3-aminomutase/glutamate 2,3-aminomutase CNX65_RS14380 6acf1d12de6ac380c22f1e450d7ce883 690 Gene3D G3DSA:3.30.420.40 1 109 4.3E-11 T 28-03-2018 CNX65_RS14380 6acf1d12de6ac380c22f1e450d7ce883 690 Gene3D G3DSA:3.30.420.40 281 662 0.0065 T 28-03-2018 CNX65_RS14380 6acf1d12de6ac380c22f1e450d7ce883 690 Pfam PF01968 Hydantoinase/oxoprolinase 209 497 9.3E-79 T 28-03-2018 IPR002821 Hydantoinase/oxoprolinase GO:0016787 Reactome: R-HSA-174403 CNX65_RS14380 6acf1d12de6ac380c22f1e450d7ce883 690 SUPERFAMILY SSF53067 8 70 5.98E-6 T 28-03-2018 CNX65_RS14380 6acf1d12de6ac380c22f1e450d7ce883 690 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 10 188 9.5E-45 T 28-03-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403 CNX65_RS07220 cb2a5fb2304ace8e80a9a40b866bd124 227 Pfam PF04493 Endonuclease V 41 219 4.3E-65 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 CNX65_RS07220 cb2a5fb2304ace8e80a9a40b866bd124 227 Hamap MF_00801 Endonuclease V [nfi]. 18 227 29.929 T 28-03-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 25 38 2.3E-54 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 143 161 2.3E-54 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 124 140 2.3E-54 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 62 81 2.3E-54 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 224 238 2.3E-54 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 173 190 2.3E-54 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 Pfam PF00771 FHIPEP family 18 660 4.7E-243 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 PIRSF PIRSF005419 1 677 2.8E-249 T 28-03-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 CNX65_RS11775 c1e1380cfd864b710172c73b81da966e 680 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 129 152 - T 28-03-2018 IPR025505 FHIPEP conserved site CNX65_RS01995 23357b7537191d3b646d1a07ffc8616e 330 Gene3D G3DSA:3.20.20.30 1 326 1.3E-72 T 28-03-2018 CNX65_RS01995 23357b7537191d3b646d1a07ffc8616e 330 SUPERFAMILY SSF51679 1 326 5.78E-74 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS01995 23357b7537191d3b646d1a07ffc8616e 330 Pfam PF00296 Luciferase-like monooxygenase 12 294 2.3E-49 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 SUPERFAMILY SSF52743 161 408 2.62E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 SUPERFAMILY SSF52743 561 663 2.62E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 Gene3D G3DSA:3.40.50.200 139 668 5.5E-75 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 255 268 5.8E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 178 197 5.8E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 PRINTS PR00723 Subtilisin serine protease family (S8) signature 599 615 5.8E-18 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 183 194 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 600 610 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 259 269 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 Gene3D G3DSA:2.60.40.1710 669 825 1.9E-4 T 28-03-2018 CNX65_RS29590 dcd2bae1ef63b4ca43b5f69995f218cb 1092 Pfam PF00082 Subtilase family 178 654 6.6E-40 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS19065 7bdf0080b665c8711d1be2dc86e5d6d6 325 Pfam PF00355 Rieske [2Fe-2S] domain 44 112 2.0E-12 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS19065 7bdf0080b665c8711d1be2dc86e5d6d6 325 SUPERFAMILY SSF50022 39 137 3.01E-20 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS19065 7bdf0080b665c8711d1be2dc86e5d6d6 325 Gene3D G3DSA:3.90.380.10 133 316 1.6E-4 T 28-03-2018 CNX65_RS19065 7bdf0080b665c8711d1be2dc86e5d6d6 325 Gene3D G3DSA:2.102.10.10 39 132 4.6E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS23995 385614865a80056d31dc22c234c0a96a 181 Gene3D G3DSA:3.30.70.1260 99 179 9.8E-19 T 28-03-2018 CNX65_RS23995 385614865a80056d31dc22c234c0a96a 181 SUPERFAMILY SSF160379 4 178 1.57E-47 T 28-03-2018 CNX65_RS23995 385614865a80056d31dc22c234c0a96a 181 PIRSF PIRSF008502 2 180 1.8E-40 T 28-03-2018 IPR012545 Protein of unknown function DUF1697 CNX65_RS23995 385614865a80056d31dc22c234c0a96a 181 Pfam PF08002 Protein of unknown function (DUF1697) 4 139 3.6E-39 T 28-03-2018 IPR012545 Protein of unknown function DUF1697 CNX65_RS23995 385614865a80056d31dc22c234c0a96a 181 Gene3D G3DSA:3.30.70.1280 2 89 1.2E-28 T 28-03-2018 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 Pfam PF00400 WD domain, G-beta repeat 236 274 0.17 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 Pfam PF00400 WD domain, G-beta repeat 366 403 0.032 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 Gene3D G3DSA:2.130.10.10 352 739 1.2E-29 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 Gene3D G3DSA:2.130.10.10 184 268 5.6E-19 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 PRINTS PR00320 G protein beta WD-40 repeat signature 390 404 5.3E-5 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 PRINTS PR00320 G protein beta WD-40 repeat signature 302 316 5.3E-5 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 PRINTS PR00320 G protein beta WD-40 repeat signature 46 60 5.3E-5 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SUPERFAMILY SSF50998 336 579 4.0E-23 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 Gene3D G3DSA:2.130.10.10 2 76 4.2E-11 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 Gene3D G3DSA:2.120.10.30 269 351 9.4E-19 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 Gene3D G3DSA:2.130.10.10 77 183 9.6E-18 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SUPERFAMILY SSF50998 185 408 1.18E-59 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SUPERFAMILY SSF50998 6 156 1.18E-59 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 193 230 8.6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 452 496 82.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 499 539 100.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 63 104 450.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 362 403 0.025 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 282 315 31.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 318 359 0.0046 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 20 59 3.2 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 233 274 4.5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 148 189 19.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS19630 ad9eb6cfa573842bc47109be5481b11e 745 SMART SM00320 107 145 0.77 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 Pfam PF00561 alpha/beta hydrolase fold 27 261 3.4E-30 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 52 67 2.9E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 221 235 2.9E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 2.9E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 PRINTS PR00412 Epoxide hydrolase signature 32 50 4.6E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 PRINTS PR00412 Epoxide hydrolase signature 219 235 4.6E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 PRINTS PR00412 Epoxide hydrolase signature 253 275 4.6E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 PRINTS PR00412 Epoxide hydrolase signature 52 67 4.6E-10 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 Gene3D G3DSA:3.40.50.1820 7 278 2.0E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20745 f24d3c32af1c746f2b4f43313cbba80c 278 SUPERFAMILY SSF53474 12 278 2.43E-64 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS32000 5f3d822fcdc90476e365fc44b1af743d 300 Gene3D G3DSA:1.10.10.10 1 88 4.8E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32000 5f3d822fcdc90476e365fc44b1af743d 300 Pfam PF03466 LysR substrate binding domain 88 297 3.5E-44 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS32000 5f3d822fcdc90476e365fc44b1af743d 300 SUPERFAMILY SSF53850 89 298 5.54E-41 T 28-03-2018 CNX65_RS32000 5f3d822fcdc90476e365fc44b1af743d 300 Gene3D G3DSA:3.40.190.10 180 268 2.1E-26 T 28-03-2018 CNX65_RS32000 5f3d822fcdc90476e365fc44b1af743d 300 Gene3D G3DSA:3.40.190.10 89 179 1.7E-26 T 28-03-2018 CNX65_RS32000 5f3d822fcdc90476e365fc44b1af743d 300 SUPERFAMILY SSF46785 1 111 1.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32000 5f3d822fcdc90476e365fc44b1af743d 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 1.0E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS19975 d3c51f44f7734d96fddbdedb5d7572f6 350 Pfam PF13409 Glutathione S-transferase, N-terminal domain 58 152 2.3E-11 T 28-03-2018 IPR004045 Glutathione S-transferase, N-terminal GO:0005515 CNX65_RS19975 d3c51f44f7734d96fddbdedb5d7572f6 350 Pfam PF13410 Glutathione S-transferase, C-terminal domain 199 268 3.0E-12 T 28-03-2018 CNX65_RS19975 d3c51f44f7734d96fddbdedb5d7572f6 350 SUPERFAMILY SSF47616 167 334 2.37E-34 T 28-03-2018 IPR010987 Glutathione S-transferase, C-terminal-like CNX65_RS19975 d3c51f44f7734d96fddbdedb5d7572f6 350 Gene3D G3DSA:3.40.30.10 29 182 3.8E-23 T 28-03-2018 CNX65_RS19975 d3c51f44f7734d96fddbdedb5d7572f6 350 PIRSF PIRSF015753 7 319 2.5E-108 T 28-03-2018 IPR016639 Glutathione S-transferase (GST) KEGG: 00480+2.5.1.18|KEGG: 00980+2.5.1.18|KEGG: 00982+2.5.1.18|MetaCyc: PWY-4061|MetaCyc: PWY-6842|MetaCyc: PWY-7112|MetaCyc: PWY-7533 CNX65_RS19975 d3c51f44f7734d96fddbdedb5d7572f6 350 Gene3D G3DSA:1.20.1050.10 183 323 2.2E-42 T 28-03-2018 CNX65_RS19975 d3c51f44f7734d96fddbdedb5d7572f6 350 SUPERFAMILY SSF52833 35 107 3.35E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS09005 be773993f20a0ed18ee7d04e113c2a7a 133 Pfam PF07498 Rho termination factor, N-terminal domain 95 122 9.7E-6 T 28-03-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 CNX65_RS09005 be773993f20a0ed18ee7d04e113c2a7a 133 Gene3D G3DSA:1.10.720.10 89 124 2.0E-10 T 28-03-2018 CNX65_RS09005 be773993f20a0ed18ee7d04e113c2a7a 133 SUPERFAMILY SSF140376 4 61 1.57E-16 T 28-03-2018 CNX65_RS09005 be773993f20a0ed18ee7d04e113c2a7a 133 Pfam PF06150 ChaB 7 61 4.0E-19 T 28-03-2018 IPR009317 ChaB CNX65_RS23865 68adbe03f839722593eac054ae6aa30e 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 59 2.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23865 68adbe03f839722593eac054ae6aa30e 206 SUPERFAMILY SSF48498 81 179 1.34E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS23865 68adbe03f839722593eac054ae6aa30e 206 SUPERFAMILY SSF46689 5 86 2.31E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23865 68adbe03f839722593eac054ae6aa30e 206 Gene3D G3DSA:1.10.10.60 1 61 5.6E-14 T 28-03-2018 CNX65_RS23865 68adbe03f839722593eac054ae6aa30e 206 Gene3D G3DSA:1.10.357.10 62 200 1.7E-13 T 28-03-2018 CNX65_RS23865 68adbe03f839722593eac054ae6aa30e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 8.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23865 68adbe03f839722593eac054ae6aa30e 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 8.3E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS06215 4fe11e6bc32f07de8939ae7318ac5e3e 113 SUPERFAMILY SSF54197 1 109 1.86E-30 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS06215 4fe11e6bc32f07de8939ae7318ac5e3e 113 PRINTS PR00332 Histidine triad family signature 5 21 2.4E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CNX65_RS06215 4fe11e6bc32f07de8939ae7318ac5e3e 113 PRINTS PR00332 Histidine triad family signature 94 104 2.4E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CNX65_RS06215 4fe11e6bc32f07de8939ae7318ac5e3e 113 PRINTS PR00332 Histidine triad family signature 26 44 2.4E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CNX65_RS06215 4fe11e6bc32f07de8939ae7318ac5e3e 113 Gene3D G3DSA:3.30.428.10 1 112 1.8E-28 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS06215 4fe11e6bc32f07de8939ae7318ac5e3e 113 Pfam PF01230 HIT domain 13 107 4.1E-20 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CNX65_RS33570 f0d801ecc51dd90e27f841ab29738b4b 399 Pfam PF00589 Phage integrase family 193 369 9.4E-14 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS33570 f0d801ecc51dd90e27f841ab29738b4b 399 SUPERFAMILY SSF56349 76 370 2.3E-49 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS33570 f0d801ecc51dd90e27f841ab29738b4b 399 Gene3D G3DSA:1.10.443.10 187 389 3.8E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS33570 f0d801ecc51dd90e27f841ab29738b4b 399 Gene3D G3DSA:1.10.150.130 65 186 9.8E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS26060 1cd0e51f77b0f9d0b963566bf85b8438 422 SUPERFAMILY SSF102645 192 409 1.7E-64 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CNX65_RS26060 1cd0e51f77b0f9d0b963566bf85b8438 422 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 13 407 1.3E-112 T 28-03-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 CNX65_RS26060 1cd0e51f77b0f9d0b963566bf85b8438 422 Pfam PF02441 Flavoprotein 13 179 1.2E-38 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CNX65_RS26060 1cd0e51f77b0f9d0b963566bf85b8438 422 Gene3D G3DSA:3.40.50.10300 189 416 1.2E-66 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CNX65_RS26060 1cd0e51f77b0f9d0b963566bf85b8438 422 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 194 382 1.3E-63 T 28-03-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 CNX65_RS26060 1cd0e51f77b0f9d0b963566bf85b8438 422 SUPERFAMILY SSF52507 11 180 1.19E-54 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CNX65_RS26060 1cd0e51f77b0f9d0b963566bf85b8438 422 Gene3D G3DSA:3.40.50.1950 8 188 2.1E-50 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CNX65_RS02755 baa0344f030a1c4c16468add20885235 932 SUPERFAMILY SSF52540 361 591 4.47E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02755 baa0344f030a1c4c16468add20885235 932 Gene3D G3DSA:3.40.50.300 223 596 1.6E-20 T 28-03-2018 CNX65_RS02755 baa0344f030a1c4c16468add20885235 932 Pfam PF01580 FtsK/SpoIIIE family 371 566 2.2E-20 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CNX65_RS03495 939c95a5cadc29af0572c32a628924ca 383 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 195 209 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS03495 939c95a5cadc29af0572c32a628924ca 383 Gene3D G3DSA:3.90.1150.10 254 383 1.7E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS03495 939c95a5cadc29af0572c32a628924ca 383 SUPERFAMILY SSF53383 12 382 8.11E-124 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS03495 939c95a5cadc29af0572c32a628924ca 383 Gene3D G3DSA:3.40.640.10 7 253 2.1E-62 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS03495 939c95a5cadc29af0572c32a628924ca 383 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 11 382 9.4E-148 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS03495 939c95a5cadc29af0572c32a628924ca 383 PIRSF PIRSF001434 1 383 2.8E-148 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS33680 688261f7782c2b046d20425528f460bc 378 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 10 332 1.7E-119 T 28-03-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 CNX65_RS33680 688261f7782c2b046d20425528f460bc 378 Gene3D G3DSA:1.10.1200.80 266 340 1.5E-17 T 28-03-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 CNX65_RS33680 688261f7782c2b046d20425528f460bc 378 Pfam PF01207 Dihydrouridine synthase (Dus) 20 325 1.6E-103 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CNX65_RS33680 688261f7782c2b046d20425528f460bc 378 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 104 122 - T 28-03-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 CNX65_RS33680 688261f7782c2b046d20425528f460bc 378 Gene3D G3DSA:3.20.20.70 15 255 3.6E-52 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS33680 688261f7782c2b046d20425528f460bc 378 PIRSF PIRSF006621 7 342 2.0E-110 T 28-03-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 CNX65_RS33680 688261f7782c2b046d20425528f460bc 378 SUPERFAMILY SSF51395 19 329 2.01E-80 T 28-03-2018 CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 SUPERFAMILY SSF52540 441 699 3.8E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 SUPERFAMILY SSF52540 1079 1263 8.6E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 TIGRFAM TIGR03924 T7SS_EccC_a: type VII secretion protein EccCa 24 698 4.2E-280 T 28-03-2018 IPR023836 EccCa-like, Actinobacteria CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 Pfam PF01580 FtsK/SpoIIIE family 812 1047 2.2E-55 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 Pfam PF01580 FtsK/SpoIIIE family 451 575 2.3E-21 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 Gene3D G3DSA:3.40.50.300 340 660 5.3E-16 T 28-03-2018 CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 Gene3D G3DSA:3.40.50.300 736 1020 1.3E-13 T 28-03-2018 CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 SUPERFAMILY SSF52540 785 1021 2.79E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32245 55eea1a8a7300b21252d1cbae2a3322a 1334 TIGRFAM TIGR03925 T7SS_EccC_b: type VII secretion protein EccCb 755 1329 3.3E-232 T 28-03-2018 IPR023837 EccCb-like, Actinobacteria CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 SMART SM01043 104 247 8.4E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 SUPERFAMILY SSF52540 326 539 1.3E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 SUPERFAMILY SSF46894 7 85 1.79E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 Gene3D G3DSA:1.25.40.10 101 273 3.0E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 Gene3D G3DSA:3.40.50.300 319 479 9.8E-8 T 28-03-2018 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 Pfam PF03704 Bacterial transcriptional activator domain 104 247 5.6E-41 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 SMART SM00862 23 106 1.4E-6 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 SUPERFAMILY SSF48452 99 260 3.42E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 Gene3D G3DSA:3.40.50.150 544 662 0.03 T 28-03-2018 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 Pfam PF13191 AAA ATPase domain 333 382 7.9E-9 T 28-03-2018 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 Pfam PF00486 Transcriptional regulatory protein, C terminal 32 85 7.3E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS14745 9ebe1fbb5db4b1bc25111b3c7c80e7bf 667 Gene3D G3DSA:1.10.10.10 1 100 5.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 3.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.7E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 3.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 3.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 3.8E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 Gene3D G3DSA:3.40.50.720 2 273 3.8E-59 T 28-03-2018 CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 Pfam PF00106 short chain dehydrogenase 6 185 3.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21280 128431a6a58353070089b176016cfeb4 276 SUPERFAMILY SSF51735 4 232 4.6E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS10915 c29ecde7b818500030a369951eef9c1f 510 Pfam PF00501 AMP-binding enzyme 36 407 3.4E-79 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS10915 c29ecde7b818500030a369951eef9c1f 510 Gene3D G3DSA:2.30.38.10 334 400 5.0E-14 T 28-03-2018 CNX65_RS10915 c29ecde7b818500030a369951eef9c1f 510 SUPERFAMILY SSF56801 4 503 2.75E-128 T 28-03-2018 CNX65_RS10915 c29ecde7b818500030a369951eef9c1f 510 Gene3D G3DSA:3.40.50.980 4 166 6.5E-32 T 28-03-2018 CNX65_RS10915 c29ecde7b818500030a369951eef9c1f 510 Gene3D G3DSA:3.30.300.30 402 510 1.8E-30 T 28-03-2018 CNX65_RS10915 c29ecde7b818500030a369951eef9c1f 510 Pfam PF13193 AMP-binding enzyme C-terminal domain 416 491 4.4E-22 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS10915 c29ecde7b818500030a369951eef9c1f 510 Gene3D G3DSA:3.40.50.980 167 326 8.9E-39 T 28-03-2018 CNX65_RS00225 140c9c339e362aeb5f743e429cffa127 182 Gene3D G3DSA:2.60.40.1220 27 125 2.3E-27 T 28-03-2018 CNX65_RS00225 140c9c339e362aeb5f743e429cffa127 182 SUPERFAMILY SSF81296 27 123 1.19E-21 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS00225 140c9c339e362aeb5f743e429cffa127 182 Pfam PF04234 CopC domain 28 123 4.6E-24 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CNX65_RS07455 147e0597143892355710720fd2325a24 474 Gene3D G3DSA:1.10.3470.10 66 468 9.1E-14 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS07455 147e0597143892355710720fd2325a24 474 Pfam PF02653 Branched-chain amino acid transport system / permease component 72 458 6.0E-32 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS04335 8e698224c022ca5ba8e8f1f970367357 380 Gene3D G3DSA:3.40.1390.30 223 359 7.9E-9 T 28-03-2018 CNX65_RS04335 8e698224c022ca5ba8e8f1f970367357 380 SUPERFAMILY SSF102705 1 369 2.09E-109 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CNX65_RS04335 8e698224c022ca5ba8e8f1f970367357 380 Gene3D G3DSA:3.40.1390.30 1 123 8.0E-36 T 28-03-2018 CNX65_RS04335 8e698224c022ca5ba8e8f1f970367357 380 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 6 352 7.4E-68 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CNX65_RS04335 8e698224c022ca5ba8e8f1f970367357 380 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 6 358 2.7E-45 T 28-03-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 CNX65_RS04335 8e698224c022ca5ba8e8f1f970367357 380 Gene3D G3DSA:3.30.70.120 131 222 3.4E-34 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CNX65_RS04335 8e698224c022ca5ba8e8f1f970367357 380 PIRSF PIRSF037489 1 371 3.4E-132 T 28-03-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria CNX65_RS13770 e36e3e25f49c048bc58b36c0b4c83bdc 351 SUPERFAMILY SSF51569 26 350 1.36E-98 T 28-03-2018 CNX65_RS13770 e36e3e25f49c048bc58b36c0b4c83bdc 351 Pfam PF00793 DAHP synthetase I family 47 338 8.3E-68 T 28-03-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 CNX65_RS13770 e36e3e25f49c048bc58b36c0b4c83bdc 351 TIGRFAM TIGR00034 aroFGH: 3-deoxy-7-phosphoheptulonate synthase 31 351 7.7E-106 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CNX65_RS13770 e36e3e25f49c048bc58b36c0b4c83bdc 351 PIRSF PIRSF001361 25 351 2.2E-112 T 28-03-2018 IPR006219 DHAP synthase, class 1 GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CNX65_RS13770 e36e3e25f49c048bc58b36c0b4c83bdc 351 Gene3D G3DSA:3.20.20.70 24 351 5.0E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS22685 77c91c5e858197293f6fd2cd2fa8c7f3 857 Gene3D G3DSA:1.25.10.10 199 533 4.7E-4 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS22685 77c91c5e858197293f6fd2cd2fa8c7f3 857 Pfam PF13576 Pentapeptide repeats (9 copies) 651 699 8.9E-11 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS22685 77c91c5e858197293f6fd2cd2fa8c7f3 857 Gene3D G3DSA:2.160.20.80 665 743 7.4E-6 T 28-03-2018 CNX65_RS22685 77c91c5e858197293f6fd2cd2fa8c7f3 857 Gene3D G3DSA:2.160.20.80 536 664 6.7E-13 T 28-03-2018 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 Pfam PF04055 Radical SAM superfamily 155 325 4.0E-28 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 155 175 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 Gene3D G3DSA:3.80.30.20 149 383 2.4E-51 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 9 418 5.5E-141 T 28-03-2018 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 SMART SM00729 151 369 3.2E-55 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 9 443 7.1E-148 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 Pfam PF00919 Uncharacterized protein family UPF0004 9 108 3.2E-29 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 SUPERFAMILY SSF102114 136 373 3.01E-55 T 28-03-2018 CNX65_RS07155 bc189069a98f8d1b215dd19d4b86c0cf 494 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 8 448 66.667 T 28-03-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 1.3E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 SUPERFAMILY SSF52172 1 129 2.28E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 5.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 5.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 5.4E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 SUPERFAMILY SSF46894 145 215 2.86E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 SMART SM00448 2 115 2.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 Pfam PF00072 Response regulator receiver domain 4 115 3.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 SMART SM00421 151 208 2.3E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 Gene3D G3DSA:1.10.10.10 127 218 1.1E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24600 561269a7bed95573dd57a865cb2dc3d3 224 Gene3D G3DSA:3.40.50.2300 1 126 1.8E-34 T 28-03-2018 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 SUPERFAMILY SSF55347 115 225 2.4E-37 T 28-03-2018 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 117 243 2.4E-28 T 28-03-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 Gene3D G3DSA:3.40.50.720 9 130 6.5E-24 T 28-03-2018 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 10 254 28.132 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 10 114 3.0E-20 T 28-03-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 PIRSF PIRSF000161 8 255 5.7E-58 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 Gene3D G3DSA:3.30.360.10 131 222 1.3E-33 T 28-03-2018 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 SUPERFAMILY SSF51735 8 141 3.94E-33 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 136 153 - T 28-03-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28550 61c9f3fbf9d94633255fc83062638f27 255 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 50 253 2.7E-53 T 28-03-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS16425 e34d50ceb509a6993ce57c922ebe8d45 275 SUPERFAMILY SSF55154 33 234 8.17E-7 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CNX65_RS16425 e34d50ceb509a6993ce57c922ebe8d45 275 Gene3D G3DSA:2.40.320.10 30 236 1.4E-28 T 28-03-2018 CNX65_RS16425 e34d50ceb509a6993ce57c922ebe8d45 275 Pfam PF09359 VTC domain 30 188 1.1E-15 T 28-03-2018 IPR018966 VTC domain CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 Pfam PF01568 Molydopterin dinucleotide binding domain 1075 1184 2.4E-20 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 15 1215 0.0 T 28-03-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 Gene3D G3DSA:3.40.50.740 113 217 0.0023 T 28-03-2018 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 53 71 - T 28-03-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 KEGG: 00910+1.7.99.4 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 SUPERFAMILY SSF50692 1066 1215 7.46E-43 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 Gene3D G3DSA:2.40.40.20 1035 1221 5.2E-44 T 28-03-2018 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 Gene3D G3DSA:3.40.228.10 727 865 3.4E-4 T 28-03-2018 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 Gene3D G3DSA:2.20.25.90 60 103 2.5E-26 T 28-03-2018 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 SMART SM00926 48 110 5.0E-5 T 28-03-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 SUPERFAMILY SSF53706 15 1053 0.0 T 28-03-2018 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 Gene3D G3DSA:3.40.228.10 228 652 4.3E-96 T 28-03-2018 CNX65_RS10425 a71aa08b6e3bdc0d8736f570eb0741b0 1221 Pfam PF00384 Molybdopterin oxidoreductase 113 821 2.7E-144 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS19135 0d6542fa5544c0622a56a3d51454f0f8 517 Pfam PF02515 CoA-transferase family III 228 469 1.1E-30 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CNX65_RS19135 0d6542fa5544c0622a56a3d51454f0f8 517 SUPERFAMILY SSF89796 11 198 1.83E-12 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS19135 0d6542fa5544c0622a56a3d51454f0f8 517 Gene3D G3DSA:3.40.50.10540 223 505 1.3E-41 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS19135 0d6542fa5544c0622a56a3d51454f0f8 517 Gene3D G3DSA:3.40.50.10540 1 214 9.1E-13 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS19135 0d6542fa5544c0622a56a3d51454f0f8 517 SUPERFAMILY SSF89796 227 266 5.49E-37 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS19135 0d6542fa5544c0622a56a3d51454f0f8 517 SUPERFAMILY SSF89796 330 472 5.49E-37 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS28105 81c241dc78d540d2ee2410a28a602788 423 SUPERFAMILY SSF103473 19 422 1.22E-73 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS28105 81c241dc78d540d2ee2410a28a602788 423 Gene3D G3DSA:1.20.1250.20 20 220 6.7E-33 T 28-03-2018 CNX65_RS28105 81c241dc78d540d2ee2410a28a602788 423 Pfam PF07690 Major Facilitator Superfamily 38 381 5.4E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS28105 81c241dc78d540d2ee2410a28a602788 423 Gene3D G3DSA:1.20.1250.20 221 423 1.8E-24 T 28-03-2018 CNX65_RS28105 81c241dc78d540d2ee2410a28a602788 423 ProSitePatterns PS00217 Sugar transport proteins signature 2. 127 152 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS06980 329a623756356b4aa2becce27e16caf8 531 Pfam PF09423 PhoD-like phosphatase 134 450 4.0E-15 T 28-03-2018 IPR018946 Alkaline phosphatase D-related CNX65_RS06980 329a623756356b4aa2becce27e16caf8 531 Gene3D G3DSA:3.60.21.10 91 527 2.6E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS06980 329a623756356b4aa2becce27e16caf8 531 SUPERFAMILY SSF56300 383 451 3.46E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS06980 329a623756356b4aa2becce27e16caf8 531 SUPERFAMILY SSF56300 282 351 3.46E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS06980 329a623756356b4aa2becce27e16caf8 531 SUPERFAMILY SSF56300 117 232 3.46E-12 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS20890 41ec321fe1c36c5ac24dc8857d2a7be7 249 Gene3D G3DSA:3.40.50.880 1 238 5.8E-45 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS20890 41ec321fe1c36c5ac24dc8857d2a7be7 249 Pfam PF03575 Peptidase family S51 3 201 4.0E-54 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CNX65_RS20890 41ec321fe1c36c5ac24dc8857d2a7be7 249 SUPERFAMILY SSF52317 4 205 6.87E-32 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS24375 32855cfd189fa8a233825ba573f42389 304 SUPERFAMILY SSF53613 24 281 7.33E-40 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS24375 32855cfd189fa8a233825ba573f42389 304 Gene3D G3DSA:3.40.1190.20 3 303 2.4E-34 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS24375 32855cfd189fa8a233825ba573f42389 304 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 239 252 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS24375 32855cfd189fa8a233825ba573f42389 304 Pfam PF00294 pfkB family carbohydrate kinase 21 283 2.2E-33 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS24375 32855cfd189fa8a233825ba573f42389 304 PIRSF PIRSF000535 10 301 2.9E-41 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CNX65_RS27245 e68c0158bcc92d0602998dfbf055d8be 282 Gene3D G3DSA:3.40.1280.10 126 282 4.2E-41 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CNX65_RS27245 e68c0158bcc92d0602998dfbf055d8be 282 SUPERFAMILY SSF75217 107 281 3.6E-38 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CNX65_RS27245 e68c0158bcc92d0602998dfbf055d8be 282 SMART SM00967 41 119 2.1E-17 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CNX65_RS27245 e68c0158bcc92d0602998dfbf055d8be 282 Gene3D G3DSA:3.30.1330.30 16 115 2.6E-24 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS27245 e68c0158bcc92d0602998dfbf055d8be 282 SUPERFAMILY SSF55315 19 116 3.65E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS27245 e68c0158bcc92d0602998dfbf055d8be 282 Pfam PF00588 SpoU rRNA Methylase family 130 274 4.2E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CNX65_RS27245 e68c0158bcc92d0602998dfbf055d8be 282 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 41 117 6.3E-15 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CNX65_RS15560 89d22078fbaa444be4c0acb34cac5898 304 Pfam PF07859 alpha/beta hydrolase fold 70 275 8.8E-50 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CNX65_RS15560 89d22078fbaa444be4c0acb34cac5898 304 Gene3D G3DSA:3.40.50.1820 4 303 2.5E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS15560 89d22078fbaa444be4c0acb34cac5898 304 SUPERFAMILY SSF53474 28 296 1.03E-47 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29820 ef4eca9a34518896554c0e00915849b3 264 Gene3D G3DSA:3.30.450.40 59 263 1.3E-13 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS29820 ef4eca9a34518896554c0e00915849b3 264 SUPERFAMILY SSF55781 116 251 9.6E-12 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS04070 200ad794ca3eb4fdfae427d6843d1bb4 225 Pfam PF13794 tRNA-(MS[2]IO[6]A)-hydroxylase (MiaE)-like 13 197 1.4E-84 T 28-03-2018 CNX65_RS04070 200ad794ca3eb4fdfae427d6843d1bb4 225 Gene3D G3DSA:1.20.1260.10 12 225 3.0E-42 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS04070 200ad794ca3eb4fdfae427d6843d1bb4 225 SUPERFAMILY SSF47240 19 165 1.62E-7 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS23340 74fbd5edb108b95a4270423c2616554a 403 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 124 338 6.4E-17 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CNX65_RS02330 6bb1283a18b01d5854b0f65e40ae6357 139 SMART SM00960 11 101 4.2E-34 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS02330 6bb1283a18b01d5854b0f65e40ae6357 139 Gene3D G3DSA:3.30.450.30 8 133 2.1E-44 T 28-03-2018 CNX65_RS02330 6bb1283a18b01d5854b0f65e40ae6357 139 Pfam PF03259 Roadblock/LC7 domain 12 101 6.8E-25 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS02330 6bb1283a18b01d5854b0f65e40ae6357 139 SUPERFAMILY SSF103196 3 128 3.84E-35 T 28-03-2018 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 4 263 2.6E-79 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 2 263 27.164 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 Gene3D G3DSA:1.10.3730.10 161 268 5.4E-42 T 28-03-2018 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 SUPERFAMILY SSF48179 158 265 1.05E-34 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 SUPERFAMILY SSF51735 3 157 9.21E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 219 241 - T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 Gene3D G3DSA:3.40.50.720 1 160 1.8E-32 T 28-03-2018 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 159 263 1.9E-36 T 28-03-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 96 2.7E-19 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 ProSitePatterns PS00616 Histidine acid phosphatases phosphohistidine signature. 234 248 - T 28-03-2018 IPR033379 Histidine acid phosphatase active site CNX65_RS33235 89a55eaebde72be664af1f71e54a2abb 270 PIRSF PIRSF000193 1 266 2.7E-71 T 28-03-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344 CNX65_RS01730 b5dcde7b4c7a43c7c8fa5c02e0cbf913 323 Gene3D G3DSA:3.60.10.10 102 323 2.3E-17 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS01730 b5dcde7b4c7a43c7c8fa5c02e0cbf913 323 SUPERFAMILY SSF56219 103 320 2.88E-25 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS01730 b5dcde7b4c7a43c7c8fa5c02e0cbf913 323 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 123 312 1.4E-10 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS00510 a5d4b8b476dc11238562f808982b47fb 203 PIRSF PIRSF000709 2 168 1.5E-6 T 28-03-2018 CNX65_RS00510 a5d4b8b476dc11238562f808982b47fb 203 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 196 4.4E-46 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS00510 a5d4b8b476dc11238562f808982b47fb 203 SUPERFAMILY SSF53254 2 198 2.86E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS00510 a5d4b8b476dc11238562f808982b47fb 203 Gene3D G3DSA:3.40.50.1240 1 202 1.1E-44 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS00510 a5d4b8b476dc11238562f808982b47fb 203 SMART SM00855 2 158 7.9E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS00510 a5d4b8b476dc11238562f808982b47fb 203 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 5 14 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 Gene3D G3DSA:3.20.20.70 46 422 8.6E-114 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 Pfam PF08502 LeuA allosteric (dimerisation) domain 468 596 4.6E-31 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 TIGRFAM TIGR00970 leuA_yeast: 2-isopropylmalate synthase 39 598 2.2E-275 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 Hamap MF_00572 2-isopropylmalate synthase [leuA]. 40 598 55.469 T 28-03-2018 IPR005668 2-isopropylmalate synthase GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 SUPERFAMILY SSF89000 434 483 7.45E-16 T 28-03-2018 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 SUPERFAMILY SSF51569 58 366 2.93E-96 T 28-03-2018 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 Pfam PF00682 HMGL-like 69 349 7.5E-78 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 279 292 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 SUPERFAMILY SSF110921 490 596 1.44E-36 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 76 92 - T 28-03-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS00995 64cea9239c2a383ff8cf33b045653ad2 598 SMART SM00917 468 597 2.7E-35 T 28-03-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 CNX65_RS01675 788a42695cc1edfd777e2e0b64fe5086 156 Gene3D G3DSA:2.40.40.20 1 117 2.7E-55 T 28-03-2018 CNX65_RS01675 788a42695cc1edfd777e2e0b64fe5086 156 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 118 1.4E-53 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CNX65_RS01675 788a42695cc1edfd777e2e0b64fe5086 156 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 130 76.329 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CNX65_RS01675 788a42695cc1edfd777e2e0b64fe5086 156 Pfam PF02261 Aspartate decarboxylase 1 114 1.1E-52 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CNX65_RS01675 788a42695cc1edfd777e2e0b64fe5086 156 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 114 1.0E-39 T 28-03-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 CNX65_RS01675 788a42695cc1edfd777e2e0b64fe5086 156 SUPERFAMILY SSF50692 1 116 7.87E-50 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 Gene3D G3DSA:3.50.50.60 348 445 1.3E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 SUPERFAMILY SSF56425 243 389 1.42E-33 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 Gene3D G3DSA:3.50.50.60 2 346 6.5E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 Gene3D G3DSA:1.20.58.100 455 570 1.0E-31 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 393 415 7.4E-9 T 28-03-2018 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 7.4E-9 T 28-03-2018 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 SUPERFAMILY SSF46977 475 620 7.06E-41 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 SUPERFAMILY SSF51905 393 470 1.1E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 SUPERFAMILY SSF51905 4 270 1.1E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 Pfam PF02910 Fumarate reductase flavoprotein C-term 484 601 6.4E-24 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 6.4E-7 T 28-03-2018 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 438 458 6.4E-7 T 28-03-2018 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 Pfam PF00890 FAD binding domain 10 429 2.2E-91 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS07065 8d4028eafed1ef0ceff77781e982c1ff 623 PIRSF PIRSF000171 1 602 3.0E-40 T 28-03-2018 CNX65_RS06065 022518a988aa69838ae6821606637987 613 SUPERFAMILY SSF54980 301 380 1.8E-18 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS06065 022518a988aa69838ae6821606637987 613 Pfam PF00009 Elongation factor Tu GTP binding domain 15 191 7.6E-51 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 PRINTS PR00315 GTP-binding elongation factor signature 17 30 3.7E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 PRINTS PR00315 GTP-binding elongation factor signature 100 111 3.7E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 PRINTS PR00315 GTP-binding elongation factor signature 60 68 3.7E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 PRINTS PR00315 GTP-binding elongation factor signature 84 94 3.7E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 PRINTS PR00315 GTP-binding elongation factor signature 136 145 3.7E-13 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 17 186 7.7E-18 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 Gene3D G3DSA:3.30.70.870 298 377 7.7E-27 T 28-03-2018 CNX65_RS06065 022518a988aa69838ae6821606637987 613 SUPERFAMILY SSF50447 175 297 1.34E-24 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS06065 022518a988aa69838ae6821606637987 613 Gene3D G3DSA:3.30.70.240 402 558 2.0E-27 T 28-03-2018 CNX65_RS06065 022518a988aa69838ae6821606637987 613 Gene3D G3DSA:3.40.50.300 13 195 9.3E-35 T 28-03-2018 CNX65_RS06065 022518a988aa69838ae6821606637987 613 TIGRFAM TIGR01393 lepA: elongation factor 4 14 605 1.8E-292 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CNX65_RS06065 022518a988aa69838ae6821606637987 613 Gene3D G3DSA:2.40.30.10 198 297 7.0E-20 T 28-03-2018 CNX65_RS06065 022518a988aa69838ae6821606637987 613 Pfam PF00679 Elongation factor G C-terminus 408 494 1.6E-21 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CNX65_RS06065 022518a988aa69838ae6821606637987 613 SUPERFAMILY SSF52540 8 215 4.18E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06065 022518a988aa69838ae6821606637987 613 SMART SM00838 407 491 0.0018 T 28-03-2018 IPR000640 Elongation factor EFG, domain V-like CNX65_RS06065 022518a988aa69838ae6821606637987 613 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CNX65_RS06065 022518a988aa69838ae6821606637987 613 SUPERFAMILY SSF54980 408 503 1.92E-22 T 28-03-2018 IPR035647 EF-G domain III/V-like CNX65_RS06065 022518a988aa69838ae6821606637987 613 Pfam PF06421 GTP-binding protein LepA C-terminus 498 602 2.1E-48 T 28-03-2018 IPR013842 GTP-binding protein LepA, C-terminal CNX65_RS06065 022518a988aa69838ae6821606637987 613 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 285.159 T 28-03-2018 IPR006297 Elongation factor 4 GO:0005525 CNX65_RS08675 0a5e36d562123a30d9402130e6612eea 187 Gene3D G3DSA:2.160.10.10 2 152 3.1E-32 T 28-03-2018 CNX65_RS08675 0a5e36d562123a30d9402130e6612eea 187 SUPERFAMILY SSF51161 17 163 2.22E-35 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS08675 0a5e36d562123a30d9402130e6612eea 187 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 17 48 3.0E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS00855 1cd46cf67b5692af26227c40ba2cacbf 318 Pfam PF02153 Prephenate dehydrogenase 39 241 1.5E-39 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CNX65_RS00855 1cd46cf67b5692af26227c40ba2cacbf 318 Gene3D G3DSA:3.40.50.720 1 168 4.2E-18 T 28-03-2018 CNX65_RS00855 1cd46cf67b5692af26227c40ba2cacbf 318 SUPERFAMILY SSF51735 3 163 7.58E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00855 1cd46cf67b5692af26227c40ba2cacbf 318 SUPERFAMILY SSF48179 167 266 1.93E-21 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS00855 1cd46cf67b5692af26227c40ba2cacbf 318 Gene3D G3DSA:1.10.3660.10 175 298 5.5E-9 T 28-03-2018 CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 Gene3D G3DSA:3.40.1710.10 46 205 6.3E-24 T 28-03-2018 CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 Gene3D G3DSA:1.10.287.950 354 402 1.7E-4 T 28-03-2018 CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 Gene3D G3DSA:1.10.287.950 276 353 8.9E-7 T 28-03-2018 CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 Pfam PF12698 ABC-2 family transporter protein 426 611 2.3E-9 T 28-03-2018 CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 414 617 3.8E-63 T 28-03-2018 IPR017501 Phage infection protein, YhgE, C-terminal CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 SUPERFAMILY SSF58104 194 394 1.18E-7 T 28-03-2018 CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 9 171 2.5E-49 T 28-03-2018 IPR017500 Phage infection protein, YhgE, N-terminal CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 204 229 1.4E-7 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CNX65_RS27520 e8114d002306394c9bef6469f78fed94 631 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 352 378 1.5E-5 T 28-03-2018 IPR023908 xxxLxxG heptad repeat CNX65_RS02535 9a574dd39dce42d8423638daa585d88d 588 Pfam PF00326 Prolyl oligopeptidase family 379 572 7.7E-43 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS02535 9a574dd39dce42d8423638daa585d88d 588 SUPERFAMILY SSF82171 10 192 1.02E-6 T 28-03-2018 CNX65_RS02535 9a574dd39dce42d8423638daa585d88d 588 Gene3D G3DSA:3.40.50.1820 324 576 1.3E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02535 9a574dd39dce42d8423638daa585d88d 588 SUPERFAMILY SSF53474 329 572 6.49E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02535 9a574dd39dce42d8423638daa585d88d 588 Gene3D G3DSA:2.140.10.30 4 323 2.6E-6 T 28-03-2018 CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 SUPERFAMILY SSF46894 371 443 9.18E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 SMART SM00421 380 437 1.9E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 ProSitePatterns PS00622 LuxR-type HTH domain signature. 397 424 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 Gene3D G3DSA:1.10.10.10 136 447 8.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 397 413 6.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 383 397 6.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 413 425 6.3E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14340 de06de375c0cd84e4fc67a4b5da37288 464 Pfam PF00196 Bacterial regulatory proteins, luxR family 383 437 9.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 Gene3D G3DSA:1.20.58.410 2 94 2.9E-21 T 28-03-2018 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 SMART SM00937 63 176 1.8E-52 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 Pfam PF03462 PCRF domain 10 201 5.7E-65 T 28-03-2018 IPR005139 Peptide chain release factor GO:0006415 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 354 37.005 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 5 352 1.7E-146 T 28-03-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 Gene3D G3DSA:3.30.160.20 207 289 6.5E-33 T 28-03-2018 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 SUPERFAMILY SSF75620 8 351 7.19E-126 T 28-03-2018 CNX65_RS30270 074a452abd5559f905e2fcc6bbe42d65 354 Pfam PF00472 RF-1 domain 212 319 3.3E-39 T 28-03-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 CNX65_RS29365 3b8698d8a2638f6b6d18137002360a3d 545 SUPERFAMILY SSF101473 4 198 6.02E-34 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS29365 3b8698d8a2638f6b6d18137002360a3d 545 SMART SM01120 34 197 6.2E-45 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS29365 3b8698d8a2638f6b6d18137002360a3d 545 SMART SM01121 229 545 4.6E-70 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CNX65_RS29365 3b8698d8a2638f6b6d18137002360a3d 545 Pfam PF13684 Dihydroxyacetone kinase family 229 545 1.8E-75 T 28-03-2018 IPR033470 Uncharacterised protein, DhaK domain CNX65_RS29365 3b8698d8a2638f6b6d18137002360a3d 545 Pfam PF02734 DAK2 domain 34 196 4.4E-32 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS29365 3b8698d8a2638f6b6d18137002360a3d 545 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 10 545 1.2E-130 T 28-03-2018 IPR019986 DAK2 domain-containing protein YloV CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 SUPERFAMILY SSF54373 334 457 7.36E-20 T 28-03-2018 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 SUPERFAMILY SSF51905 6 290 2.72E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 SUPERFAMILY SSF51905 456 515 2.72E-70 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 Pfam PF05199 GMC oxidoreductase 370 508 1.9E-35 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 Gene3D G3DSA:4.10.450.10 47 103 8.2E-11 T 28-03-2018 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 256 270 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 Pfam PF00732 GMC oxidoreductase 7 295 4.0E-62 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 PIRSF PIRSF000137 3 516 1.1E-109 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20410 607a1c295427026a8211820409a5ef2b 516 Gene3D G3DSA:3.30.560.10 104 472 1.3E-85 T 28-03-2018 CNX65_RS08665 71b45c538f0be4e782647f7fe9e8bf21 218 Gene3D G3DSA:2.160.10.10 90 218 6.7E-29 T 28-03-2018 CNX65_RS08665 71b45c538f0be4e782647f7fe9e8bf21 218 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 161 193 0.0028 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS08665 71b45c538f0be4e782647f7fe9e8bf21 218 TIGRFAM TIGR03570 NeuD_NnaD: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family 6 209 1.8E-52 T 28-03-2018 IPR020019 Sialic acid O-acyltransferase NeuD-like CNX65_RS08665 71b45c538f0be4e782647f7fe9e8bf21 218 Gene3D G3DSA:3.40.50.720 2 89 4.2E-14 T 28-03-2018 CNX65_RS08665 71b45c538f0be4e782647f7fe9e8bf21 218 SUPERFAMILY SSF51161 68 215 1.05E-34 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS08665 71b45c538f0be4e782647f7fe9e8bf21 218 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 169 197 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CNX65_RS08665 71b45c538f0be4e782647f7fe9e8bf21 218 SUPERFAMILY SSF53335 3 72 8.8E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS07420 81fd950194b677e443f805af0739134e 300 SUPERFAMILY SSF53613 7 293 5.61E-68 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS07420 81fd950194b677e443f805af0739134e 300 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 247 260 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS07420 81fd950194b677e443f805af0739134e 300 Gene3D G3DSA:3.40.1190.20 5 297 7.3E-63 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS07420 81fd950194b677e443f805af0739134e 300 Pfam PF00294 pfkB family carbohydrate kinase 8 293 6.6E-53 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS07420 81fd950194b677e443f805af0739134e 300 PRINTS PR00990 Ribokinase signature 218 229 1.8E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS07420 81fd950194b677e443f805af0739134e 300 PRINTS PR00990 Ribokinase signature 36 55 1.8E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS07420 81fd950194b677e443f805af0739134e 300 PRINTS PR00990 Ribokinase signature 107 120 1.8E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS07420 81fd950194b677e443f805af0739134e 300 PRINTS PR00990 Ribokinase signature 181 196 1.8E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS07420 81fd950194b677e443f805af0739134e 300 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 41 65 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS09595 8cb6ab7784f4b5e65fe8b11f83509040 174 Gene3D G3DSA:3.30.565.10 17 125 1.8E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16870 edaea46e95b764ef885514e42ea1935e 168 Pfam PF13420 Acetyltransferase (GNAT) domain 8 161 1.3E-20 T 28-03-2018 CNX65_RS16870 edaea46e95b764ef885514e42ea1935e 168 SUPERFAMILY SSF55729 6 167 3.6E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS16870 edaea46e95b764ef885514e42ea1935e 168 Gene3D G3DSA:3.40.630.30 4 168 2.7E-28 T 28-03-2018 CNX65_RS04405 eded072db84c4b970421755dc194bd75 222 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 9 105 6.2E-21 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CNX65_RS04405 eded072db84c4b970421755dc194bd75 222 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 7 219 3.5E-74 T 28-03-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 CNX65_RS04405 eded072db84c4b970421755dc194bd75 222 SUPERFAMILY SSF51735 8 216 6.26E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS04405 eded072db84c4b970421755dc194bd75 222 Gene3D G3DSA:3.40.50.720 8 218 2.3E-29 T 28-03-2018 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Gene3D G3DSA:2.40.50.140 369 491 1.5E-28 T 28-03-2018 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 72 503 2.4E-72 T 28-03-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 SUPERFAMILY SSF117018 1 204 2.22E-27 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Hamap MF_00407 DNA ligase [lig]. 1 505 25.647 T 28-03-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Pfam PF04679 ATP dependent DNA ligase C terminal region 398 489 2.5E-9 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 SUPERFAMILY SSF50249 380 504 1.34E-28 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 SUPERFAMILY SSF56091 185 378 1.53E-45 T 28-03-2018 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Pfam PF04675 DNA ligase N terminus 69 143 2.0E-8 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 213 221 - T 28-03-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Gene3D G3DSA:1.10.3260.10 53 180 2.5E-22 T 28-03-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Pfam PF01068 ATP dependent DNA ligase domain 191 378 6.6E-39 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Gene3D G3DSA:3.30.470.30 181 316 7.5E-33 T 28-03-2018 CNX65_RS03580 ebbe2cf22685d6ecb7dcf367c3badc86 539 Gene3D G3DSA:3.30.1490.70 317 368 2.1E-15 T 28-03-2018 CNX65_RS23825 c1e2f6e9071ca5998e49598153d0888c 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 2.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23825 c1e2f6e9071ca5998e49598153d0888c 187 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 2.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23825 c1e2f6e9071ca5998e49598153d0888c 187 Gene3D G3DSA:1.10.357.10 53 187 3.8E-20 T 28-03-2018 CNX65_RS23825 c1e2f6e9071ca5998e49598153d0888c 187 SUPERFAMILY SSF46689 3 79 4.73E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23825 c1e2f6e9071ca5998e49598153d0888c 187 Gene3D G3DSA:1.10.10.60 7 52 4.8E-16 T 28-03-2018 CNX65_RS23825 c1e2f6e9071ca5998e49598153d0888c 187 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 55 5.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23825 c1e2f6e9071ca5998e49598153d0888c 187 ProSitePatterns PS01081 TetR-type HTH domain signature. 24 55 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS26470 3c64062db6e0a1994e867a20850f6891 279 PRINTS PR00069 Aldo-keto reductase signature 141 158 1.4E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS26470 3c64062db6e0a1994e867a20850f6891 279 PRINTS PR00069 Aldo-keto reductase signature 212 236 1.4E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS26470 3c64062db6e0a1994e867a20850f6891 279 PRINTS PR00069 Aldo-keto reductase signature 110 128 1.4E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS26470 3c64062db6e0a1994e867a20850f6891 279 PRINTS PR00069 Aldo-keto reductase signature 45 69 1.4E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS26470 3c64062db6e0a1994e867a20850f6891 279 Gene3D G3DSA:3.20.20.100 3 279 2.8E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS26470 3c64062db6e0a1994e867a20850f6891 279 Pfam PF00248 Aldo/keto reductase family 15 278 9.7E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS26470 3c64062db6e0a1994e867a20850f6891 279 SUPERFAMILY SSF51430 5 278 2.23E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS28525 1b01dd69856f90994f4333d3ff26bfe0 332 Pfam PF00248 Aldo/keto reductase family 16 309 1.6E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS28525 1b01dd69856f90994f4333d3ff26bfe0 332 Gene3D G3DSA:3.20.20.100 2 331 1.6E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS28525 1b01dd69856f90994f4333d3ff26bfe0 332 SUPERFAMILY SSF51430 5 310 8.12E-88 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 SUPERFAMILY SSF53098 790 955 8.18E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 Pfam PF00270 DEAD/DEAH box helicase 36 206 2.2E-28 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 SMART SM00479 792 959 1.3E-31 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 SMART SM00490 303 390 5.1E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 SMART SM00487 30 242 5.1E-31 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 Pfam PF00271 Helicase conserved C-terminal domain 286 390 7.7E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 791 951 3.8E-24 T 28-03-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 Pfam PF00929 Exonuclease 795 949 2.7E-24 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 Gene3D G3DSA:3.40.50.300 6 244 1.6E-35 T 28-03-2018 CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 SUPERFAMILY SSF52540 42 208 1.12E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 SUPERFAMILY SSF52540 258 393 1.12E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 Gene3D G3DSA:3.40.50.300 270 419 3.5E-25 T 28-03-2018 CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 Gene3D G3DSA:1.10.10.10 420 695 0.0093 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21905 20902076a9ef41231ec0506215dbd8b8 967 Gene3D G3DSA:3.30.420.10 789 959 2.0E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS26370 4ef9ce346e3b7a008aed57bb19bfbdab 320 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 23 85 4.5E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS26370 4ef9ce346e3b7a008aed57bb19bfbdab 320 SUPERFAMILY SSF51735 130 290 1.3E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26370 4ef9ce346e3b7a008aed57bb19bfbdab 320 SUPERFAMILY SSF50129 10 156 2.89E-38 T 28-03-2018 IPR011032 GroES-like CNX65_RS26370 4ef9ce346e3b7a008aed57bb19bfbdab 320 Gene3D G3DSA:3.90.180.10 1 320 1.7E-62 T 28-03-2018 CNX65_RS26370 4ef9ce346e3b7a008aed57bb19bfbdab 320 Pfam PF00107 Zinc-binding dehydrogenase 162 282 2.7E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS26370 4ef9ce346e3b7a008aed57bb19bfbdab 320 SMART SM00829 4 317 9.4E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Gene3D G3DSA:1.50.10.10 266 443 1.5E-12 T 28-03-2018 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Gene3D G3DSA:1.50.10.10 86 265 1.3E-18 T 28-03-2018 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 716 771 1.1E-9 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 626 708 4.6E-17 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 54 571 6.9E-144 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Gene3D G3DSA:2.80.10.50 709 771 1.2E-15 T 28-03-2018 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Gene3D G3DSA:2.80.10.50 674 708 5.0E-13 T 28-03-2018 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 Gene3D G3DSA:2.80.10.50 448 673 4.3E-13 T 28-03-2018 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 SUPERFAMILY SSF50370 632 768 2.75E-38 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 SUPERFAMILY SSF48208 112 146 1.19E-12 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS15740 3ac69c81023c471f1e383e55c07bb9dc 771 SUPERFAMILY SSF48208 173 409 1.19E-12 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS04340 17d17143a9451fe3a0ff7eb71dadc1e7 245 Gene3D G3DSA:1.20.5.730 12 87 9.3E-4 T 28-03-2018 CNX65_RS04340 17d17143a9451fe3a0ff7eb71dadc1e7 245 Pfam PF02591 C4-type zinc ribbon domain 203 237 7.1E-10 T 28-03-2018 IPR003743 C4-type zinc ribbon domain CNX65_RS04340 17d17143a9451fe3a0ff7eb71dadc1e7 245 Gene3D G3DSA:1.20.5.340 92 191 1.8E-5 T 28-03-2018 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 SUPERFAMILY SSF56176 2 216 9.35E-77 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 Gene3D G3DSA:1.10.45.10 422 454 2.4E-13 T 28-03-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 Gene3D G3DSA:3.30.43.10 1 92 1.6E-24 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 Pfam PF01565 FAD binding domain 40 179 1.3E-43 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 216 453 7.5E-61 T 28-03-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 Gene3D G3DSA:3.30.465.10 93 237 1.2E-45 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 Gene3D G3DSA:3.40.50.2300 253 421 0.2 T 28-03-2018 CNX65_RS34225 8c21eb7134926e578f2d4f3ab1b23adf 461 SUPERFAMILY SSF55103 220 457 3.27E-57 T 28-03-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 72 296 1.3E-9 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 SUPERFAMILY SSF51905 378 595 1.17E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 73 92 9.4E-5 T 28-03-2018 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 249 267 9.4E-5 T 28-03-2018 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 SUPERFAMILY SSF51905 68 303 3.31E-43 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 Gene3D G3DSA:3.50.50.60 242 603 3.5E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 249 274 2.3E-5 T 28-03-2018 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 72 94 2.3E-5 T 28-03-2018 CNX65_RS24050 edd1ddcad4a2566ed44d0801889ab6c6 606 Gene3D G3DSA:3.50.50.60 68 241 4.8E-29 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19075 68110c671651781c8b8549572dec2317 230 SUPERFAMILY SSF53335 9 213 1.43E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS19075 68110c671651781c8b8549572dec2317 230 Gene3D G3DSA:3.40.50.150 2 226 1.8E-31 T 28-03-2018 CNX65_RS19075 68110c671651781c8b8549572dec2317 230 Pfam PF01209 ubiE/COQ5 methyltransferase family 6 215 2.2E-21 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CNX65_RS01920 7e04cb9917c75f071c4723635a80565c 323 Gene3D G3DSA:1.10.10.10 109 323 2.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01920 7e04cb9917c75f071c4723635a80565c 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 280 295 2.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS01920 7e04cb9917c75f071c4723635a80565c 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 295 310 2.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS01920 7e04cb9917c75f071c4723635a80565c 323 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 249 264 2.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS01920 7e04cb9917c75f071c4723635a80565c 323 SMART SM00418 247 322 1.0E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS01920 7e04cb9917c75f071c4723635a80565c 323 SUPERFAMILY SSF46785 232 312 1.79E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01920 7e04cb9917c75f071c4723635a80565c 323 Pfam PF12840 Helix-turn-helix domain 251 304 6.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08455 83829b2c4ec3198e2dc95afa002de361 130 Pfam PF02699 Preprotein translocase subunit 7 83 2.9E-20 T 28-03-2018 IPR003849 Preprotein translocase YajC CNX65_RS08455 83829b2c4ec3198e2dc95afa002de361 130 SMART SM01323 4 86 8.9E-27 T 28-03-2018 IPR003849 Preprotein translocase YajC CNX65_RS08455 83829b2c4ec3198e2dc95afa002de361 130 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 10 86 5.8E-18 T 28-03-2018 IPR003849 Preprotein translocase YajC CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 SUPERFAMILY SSF54862 1 485 5.13E-155 T 28-03-2018 CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 Gene3D G3DSA:3.30.70.20 235 370 5.0E-26 T 28-03-2018 CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 Gene3D G3DSA:3.30.70.20 371 468 1.9E-25 T 28-03-2018 CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 Gene3D G3DSA:3.30.70.20 5 196 3.0E-29 T 28-03-2018 CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 485 2.1E-228 T 28-03-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.99.4 CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 357 437 1.1E-25 T 28-03-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.99.4 CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 Pfam PF13247 4Fe-4S dicluster domain 174 269 3.4E-35 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS10420 688a7001edb08ae6d1924ded1c9b4016 511 Gene3D G3DSA:3.30.70.20 197 234 3.0E-18 T 28-03-2018 CNX65_RS14330 ac8512cc55aa0addca30673061c3631e 111 SUPERFAMILY SSF54909 1 109 2.57E-27 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS14330 ac8512cc55aa0addca30673061c3631e 111 Pfam PF07110 EthD domain 12 97 9.1E-17 T 28-03-2018 IPR009799 EthD domain CNX65_RS14330 ac8512cc55aa0addca30673061c3631e 111 Gene3D G3DSA:3.30.70.100 2 106 2.4E-25 T 28-03-2018 CNX65_RS14330 ac8512cc55aa0addca30673061c3631e 111 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 5 108 8.5E-9 T 28-03-2018 IPR009799 EthD domain CNX65_RS34600 330656f1a4f628146512196fa4839bca 289 Pfam PF13560 Helix-turn-helix domain 12 71 1.6E-10 T 28-03-2018 CNX65_RS34600 330656f1a4f628146512196fa4839bca 289 SMART SM00530 16 71 1.8E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS34600 330656f1a4f628146512196fa4839bca 289 SUPERFAMILY SSF47413 9 68 4.79E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS34600 330656f1a4f628146512196fa4839bca 289 Gene3D G3DSA:1.10.260.40 2 89 3.3E-9 T 28-03-2018 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 SUPERFAMILY SSF46894 143 210 1.53E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 207 1.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 Pfam PF00072 Response regulator receiver domain 5 116 3.3E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 SUPERFAMILY SSF52172 3 133 8.4E-32 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 SMART SM00421 152 209 8.3E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.7E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 SMART SM00448 3 116 9.3E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 Gene3D G3DSA:1.10.10.10 135 214 4.5E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS10035 98eeb7c3aa2cf69a7386efece2f769fd 214 Gene3D G3DSA:3.40.50.2300 2 134 4.1E-36 T 28-03-2018 CNX65_RS33780 550457f8b898f6a60a96470c6b191434 200 Gene3D G3DSA:3.30.1360.40 1 77 2.4E-15 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CNX65_RS33780 550457f8b898f6a60a96470c6b191434 200 SUPERFAMILY SSF160467 2 82 1.57E-7 T 28-03-2018 CNX65_RS33780 550457f8b898f6a60a96470c6b191434 200 Gene3D G3DSA:2.40.100.10 78 200 1.8E-51 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS33780 550457f8b898f6a60a96470c6b191434 200 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 1 189 1.2E-63 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CNX65_RS33780 550457f8b898f6a60a96470c6b191434 200 SUPERFAMILY SSF50891 78 199 9.86E-40 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS33780 550457f8b898f6a60a96470c6b191434 200 SMART SM00796 1 189 2.1E-82 T 28-03-2018 IPR003833 Carboxyltransferase domain, subdomain C and D CNX65_RS20955 eeb77a64ca0e973e674dc389b78cd44c 491 Gene3D G3DSA:3.40.50.620 236 433 0.0014 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS20955 eeb77a64ca0e973e674dc389b78cd44c 491 Gene3D G3DSA:3.40.50.620 161 235 4.7E-4 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS02615 02abac382e1f5d9a358f5058adaaeda9 377 Gene3D G3DSA:3.40.640.10 28 265 5.2E-20 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS02615 02abac382e1f5d9a358f5058adaaeda9 377 Gene3D G3DSA:3.90.1150.10 266 376 2.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS02615 02abac382e1f5d9a358f5058adaaeda9 377 Pfam PF00266 Aminotransferase class-V 26 336 6.2E-15 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS02615 02abac382e1f5d9a358f5058adaaeda9 377 SUPERFAMILY SSF53383 21 374 1.24E-75 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS02615 02abac382e1f5d9a358f5058adaaeda9 377 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 11 377 24.037 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CNX65_RS02615 02abac382e1f5d9a358f5058adaaeda9 377 TIGRFAM TIGR01366 serC_3: putative phosphoserine aminotransferase 17 376 2.9E-197 T 28-03-2018 IPR006272 Phosphoserine aminotransferase, Mycobacterial-type GO:0004648|GO:0006564|GO:0009058 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52 CNX65_RS02615 02abac382e1f5d9a358f5058adaaeda9 377 PIRSF PIRSF000525 10 377 1.2E-75 T 28-03-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 CNX65_RS22130 39a517a6f430d654643350e9a8b5904f 181 Pfam PF02627 Carboxymuconolactone decarboxylase family 46 101 1.0E-7 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS22130 39a517a6f430d654643350e9a8b5904f 181 Gene3D G3DSA:1.20.5.810 11 42 1.7E-13 T 28-03-2018 CNX65_RS22130 39a517a6f430d654643350e9a8b5904f 181 TIGRFAM TIGR01926 peroxid_rel: uncharacterized peroxidase-related enzyme 2 170 2.5E-27 T 28-03-2018 IPR010195 Uncharacterised peroxidase-related CNX65_RS22130 39a517a6f430d654643350e9a8b5904f 181 SUPERFAMILY SSF69118 1 175 1.44E-52 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS22130 39a517a6f430d654643350e9a8b5904f 181 Gene3D G3DSA:1.20.1290.10 43 176 2.7E-33 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS22130 39a517a6f430d654643350e9a8b5904f 181 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 61 103 2.5E-12 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS31280 712cc43d55346e90d79d3d6112278033 283 Gene3D G3DSA:3.40.50.300 5 241 1.0E-53 T 28-03-2018 CNX65_RS31280 712cc43d55346e90d79d3d6112278033 283 SMART SM00382 33 200 3.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS31280 712cc43d55346e90d79d3d6112278033 283 SUPERFAMILY SSF52540 9 214 7.35E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31280 712cc43d55346e90d79d3d6112278033 283 Pfam PF00005 ABC transporter 24 150 4.5E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 1066 1223 1.78E-19 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF13193 AMP-binding enzyme C-terminal domain 2380 2450 5.5E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF13193 AMP-binding enzyme C-terminal domain 893 967 9.0E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00668 Condensation domain 3002 3402 2.8E-38 T 28-03-2018 IPR001242 Condensation domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00668 Condensation domain 16 359 8.6E-33 T 28-03-2018 IPR001242 Condensation domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00668 Condensation domain 1103 1393 9.7E-25 T 28-03-2018 IPR001242 Condensation domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00668 Condensation domain 1529 1956 9.3E-68 T 28-03-2018 IPR001242 Condensation domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00668 Condensation domain 2594 2891 9.6E-26 T 28-03-2018 IPR001242 Condensation domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1998 2396 7.7E-124 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 502 908 2.5E-101 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 TIGRFAM TIGR01720 NRPS-para261: non-ribosomal peptide synthase domain TIGR01720 1367 1520 9.2E-23 T 28-03-2018 IPR010060 Non-ribosomal peptide synthase CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.40.50.980 476 629 1.8E-31 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.40.50.980 1972 2123 6.7E-41 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SMART SM00823 Phosphopantetheine attachment site 987 1045 0.04 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SMART SM00823 Phosphopantetheine attachment site 2474 2541 5.7E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF56801 1942 2486 3.92E-143 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:2.30.38.10 797 875 1.6E-22 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:2.30.38.10 2281 2362 1.7E-24 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 2727 2969 4.6E-31 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1014 1029 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 2548 2741 1.78E-23 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 1257 1495 2.22E-26 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2122 2133 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF56801 461 1000 3.53E-114 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF47336 983 1052 2.59E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 206 466 1.45E-31 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 1527 1717 1.45E-36 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 1703 1946 3.45E-47 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.40.50.980 2124 2274 1.5E-32 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 ProSitePatterns PS00012 Phosphopantetheine attachment site. 2497 2512 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00550 Phosphopantetheine attachment site 2476 2536 5.9E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00550 Phosphopantetheine attachment site 992 1052 2.8E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.30.300.30 2365 2462 3.8E-30 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 18 198 1.63E-25 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.30.300.30 879 976 1.4E-29 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.40.50.980 630 796 1.1E-26 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 3000 3181 6.34E-31 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.30.559.10 2 211 9.5E-18 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.30.559.10 2984 3180 5.5E-29 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00501 AMP-binding enzyme 1979 2372 3.6E-92 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Pfam PF00501 AMP-binding enzyme 487 885 6.5E-74 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF52777 3171 3401 1.11E-37 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.30.559.10 1057 1240 1.1E-18 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 ProSitePatterns PS00455 Putative AMP-binding domain signature. 625 636 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.30.559.10 1526 1723 4.6E-34 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:3.30.559.10 2582 2744 5.3E-23 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 SUPERFAMILY SSF47336 2467 2535 1.41E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:1.10.1200.10 2463 2550 9.3E-15 T 28-03-2018 CNX65_RS13780 cad3147ac22d7da88ddae8a79c84c3d8 3417 Gene3D G3DSA:1.10.1200.10 977 1056 5.0E-17 T 28-03-2018 CNX65_RS28350 41cea46f9c159e1c45b09ba212d0a17c 363 Pfam PF04909 Amidohydrolase 202 362 6.6E-7 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS28350 41cea46f9c159e1c45b09ba212d0a17c 363 Gene3D G3DSA:3.20.20.140 111 362 2.3E-62 T 28-03-2018 CNX65_RS28350 41cea46f9c159e1c45b09ba212d0a17c 363 SUPERFAMILY SSF51556 6 362 3.29E-11 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 SUPERFAMILY SSF54211 9 150 1.97E-26 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 PIRSF PIRSF000676 6 288 4.8E-72 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 91 102 - T 28-03-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 Pfam PF00288 GHMP kinases N terminal domain 85 144 6.3E-12 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 TIGRFAM TIGR00191 thrB: homoserine kinase 9 267 1.5E-60 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 Pfam PF08544 GHMP kinases C terminal 223 263 3.3E-5 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 Gene3D G3DSA:3.30.230.10 9 158 1.5E-31 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 SUPERFAMILY SSF55060 166 266 9.11E-21 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 PRINTS PR00958 Homoserine kinase signature 131 144 8.4E-33 T 28-03-2018 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 PRINTS PR00958 Homoserine kinase signature 98 113 8.4E-33 T 28-03-2018 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 PRINTS PR00958 Homoserine kinase signature 16 31 8.4E-33 T 28-03-2018 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 PRINTS PR00958 Homoserine kinase signature 170 187 8.4E-33 T 28-03-2018 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 PRINTS PR00958 Homoserine kinase signature 247 262 8.4E-33 T 28-03-2018 CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 Gene3D G3DSA:3.30.70.890 162 293 2.6E-22 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS30290 c620674e861dc9fbc91d135e2a0597f7 295 Hamap MF_00384 Homoserine kinase [thrB]. 9 291 27.484 T 28-03-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 CNX65_RS02450 975715c33a5e91a25758ac66eb9a4b85 128 Gene3D G3DSA:2.40.50.140 2 74 1.2E-18 T 28-03-2018 CNX65_RS02450 975715c33a5e91a25758ac66eb9a4b85 128 Pfam PF00313 'Cold-shock' DNA-binding domain 3 64 6.7E-16 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02450 975715c33a5e91a25758ac66eb9a4b85 128 PRINTS PR00050 Cold shock protein signature 24 33 6.2E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02450 975715c33a5e91a25758ac66eb9a4b85 128 PRINTS PR00050 Cold shock protein signature 38 56 6.2E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02450 975715c33a5e91a25758ac66eb9a4b85 128 PRINTS PR00050 Cold shock protein signature 4 19 6.2E-12 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02450 975715c33a5e91a25758ac66eb9a4b85 128 SUPERFAMILY SSF50249 2 65 5.14E-17 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS02450 975715c33a5e91a25758ac66eb9a4b85 128 SMART SM00357 3 65 3.7E-21 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CNX65_RS07195 8d6549f8df5c6039336381f8e47e43b2 269 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 47 133 0.004 T 28-03-2018 CNX65_RS07195 8d6549f8df5c6039336381f8e47e43b2 269 Pfam PF12787 EcsC protein family 47 209 2.0E-14 T 28-03-2018 IPR024787 EcsC protein CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 SMART SM00028 99 132 7.7 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 SMART SM00028 201 234 75.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 SMART SM00028 133 166 0.0032 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 SMART SM00028 279 309 330.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 SMART SM00028 167 200 0.03 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 SUPERFAMILY SSF48452 199 299 6.88E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 Gene3D G3DSA:1.10.287.1110 152 165 4.1E-5 T 28-03-2018 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 Pfam PF13432 Tetratricopeptide repeat 139 198 3.2E-8 T 28-03-2018 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 Pfam PF13432 Tetratricopeptide repeat 256 305 8.3E-6 T 28-03-2018 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 Gene3D G3DSA:1.25.40.10 166 217 4.8E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 Gene3D G3DSA:1.25.40.10 93 151 1.5E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 Pfam PF07721 Tetratricopeptide repeat 202 226 0.73 T 28-03-2018 IPR011717 Tetratricopeptide TPR-4 GO:0042802 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 Gene3D G3DSA:1.25.40.10 218 309 3.8E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11590 c805a4ed584411fa18694bcebf169d17 309 SUPERFAMILY SSF48452 96 231 1.78E-27 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS01295 602036f8e30026eb06f479cec58d1dcc 270 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 12 211 2.6E-66 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CNX65_RS01295 602036f8e30026eb06f479cec58d1dcc 270 Pfam PF12710 haloacid dehalogenase-like hydrolase 13 198 1.9E-32 T 28-03-2018 CNX65_RS01295 602036f8e30026eb06f479cec58d1dcc 270 SUPERFAMILY SSF56784 11 221 4.46E-28 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS01295 602036f8e30026eb06f479cec58d1dcc 270 Gene3D G3DSA:3.40.50.1000 12 233 2.7E-19 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS01295 602036f8e30026eb06f479cec58d1dcc 270 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 12 200 3.8E-23 T 28-03-2018 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 488 514 3.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 75 3.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 77 102 3.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 272 295 3.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 36 58 3.5E-44 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00458 Haem peroxidase superfamily signature 178 190 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00458 Haem peroxidase superfamily signature 324 339 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00458 Haem peroxidase superfamily signature 100 114 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00458 Haem peroxidase superfamily signature 160 177 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 PRINTS PR00458 Haem peroxidase superfamily signature 264 279 1.9E-18 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 SUPERFAMILY SSF48113 28 437 2.8E-154 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 Hamap MF_01961 Catalase-peroxidase [katG]. 15 744 41.838 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 Pfam PF00141 Peroxidase 410 718 1.0E-39 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 Pfam PF00141 Peroxidase 94 403 2.7E-49 T 28-03-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 32 744 0.0 T 28-03-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|MetaCyc: PWY-5506 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 SUPERFAMILY SSF48113 438 743 8.1E-110 T 28-03-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 Gene3D G3DSA:1.10.520.10 66 225 4.0E-36 T 28-03-2018 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 ProSitePatterns PS00436 Peroxidases active site signature. 100 111 - T 28-03-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 Gene3D G3DSA:1.10.520.10 449 610 1.4E-41 T 28-03-2018 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 Gene3D G3DSA:1.10.420.10 238 405 8.1E-40 T 28-03-2018 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 Gene3D G3DSA:1.10.420.10 611 719 3.4E-35 T 28-03-2018 CNX65_RS20995 589318fece9e2fbb3e4843342cdaec02 744 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 264 274 - T 28-03-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 TIGRFAM TIGR01443 intein_Cterm: intein C-terminal splicing region 378 400 1.1E-4 T 28-03-2018 IPR030934 Intein C-terminal splicing region CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SUPERFAMILY SSF101904 836 1103 9.42E-41 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:3.30.1360.40 562 662 1.4E-24 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SMART SM00434 362 794 1.3E-174 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SUPERFAMILY SSF56719 396 816 1.03E-129 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SUPERFAMILY SSF56719 22 88 1.12E-21 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:3.90.199.10 392 539 5.5E-57 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:2.120.10.90 835 1112 1.2E-48 T 28-03-2018 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 PRINTS PR00379 Intein signature 192 204 3.7E-6 T 28-03-2018 IPR006142 Intein GO:0016539 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 PRINTS PR00379 Intein signature 305 320 3.7E-6 T 28-03-2018 IPR006142 Intein GO:0016539 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 PRINTS PR00379 Intein signature 394 403 3.7E-6 T 28-03-2018 IPR006142 Intein GO:0016539 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 PRINTS PR00379 Intein signature 279 291 3.7E-6 T 28-03-2018 IPR006142 Intein GO:0016539 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 PRINTS PR00379 Intein signature 142 155 3.7E-6 T 28-03-2018 IPR006142 Intein GO:0016539 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:3.90.199.10 49 94 9.8E-13 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:3.10.28.10 267 330 0.0015 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 396 794 9.7E-121 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 47 88 7.7E-13 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SUPERFAMILY SSF51294 334 399 5.49E-23 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SUPERFAMILY SSF51294 88 203 5.49E-23 T 28-03-2018 IPR028992 Hedgehog/Intein (Hint) domain Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:2.170.16.10 343 391 7.8E-8 T 28-03-2018 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:2.170.16.10 95 231 1.6E-17 T 28-03-2018 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Gene3D G3DSA:1.10.268.10 674 816 7.1E-41 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 888 940 1.7 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 1060 1080 0.27 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SMART SM00306 86 179 3.4E-4 T 28-03-2018 IPR003587 Hint domain N-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS11605 b0453b7f3dc1a475d7309f6583d46876 1138 SMART SM00305 361 405 3.3E-4 T 28-03-2018 IPR003586 Hint domain C-terminal Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 CNX65_RS07180 f4267eff0b06eef1a9e0e2d16009a966 295 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 81 94 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CNX65_RS07180 f4267eff0b06eef1a9e0e2d16009a966 295 Gene3D G3DSA:3.40.190.10 162 245 2.8E-24 T 28-03-2018 CNX65_RS07180 f4267eff0b06eef1a9e0e2d16009a966 295 SMART SM00062 57 283 2.9E-62 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS07180 f4267eff0b06eef1a9e0e2d16009a966 295 Gene3D G3DSA:3.40.190.10 47 161 6.6E-28 T 28-03-2018 CNX65_RS07180 f4267eff0b06eef1a9e0e2d16009a966 295 SUPERFAMILY SSF53850 1 277 1.16E-58 T 28-03-2018 CNX65_RS07180 f4267eff0b06eef1a9e0e2d16009a966 295 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 58 278 2.2E-52 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS26300 3604ced2a1b7784839e0d890d80dc196 184 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 5.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS26300 3604ced2a1b7784839e0d890d80dc196 184 Gene3D G3DSA:1.10.357.10 71 182 2.9E-16 T 28-03-2018 CNX65_RS26300 3604ced2a1b7784839e0d890d80dc196 184 Gene3D G3DSA:1.10.10.60 51 70 2.2E-5 T 28-03-2018 CNX65_RS26300 3604ced2a1b7784839e0d890d80dc196 184 Pfam PF13305 WHG domain 85 164 2.9E-12 T 28-03-2018 IPR025996 WHG domain CNX65_RS26300 3604ced2a1b7784839e0d890d80dc196 184 SUPERFAMILY SSF48498 80 171 6.5E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS26300 3604ced2a1b7784839e0d890d80dc196 184 SUPERFAMILY SSF46689 6 78 4.46E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS26300 3604ced2a1b7784839e0d890d80dc196 184 Gene3D G3DSA:1.10.10.60 1 50 7.5E-15 T 28-03-2018 CNX65_RS02275 1668d3acd0385e5c5fe5809bc3b0a2b6 277 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 263 5.8E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02275 1668d3acd0385e5c5fe5809bc3b0a2b6 277 SUPERFAMILY SSF161098 2 272 1.12E-62 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02275 1668d3acd0385e5c5fe5809bc3b0a2b6 277 Gene3D G3DSA:1.10.3720.10 6 266 1.6E-40 T 28-03-2018 CNX65_RS04970 1ed52faa5d9317eb788f2937d59a9d37 261 Gene3D G3DSA:3.40.1490.10 172 261 6.3E-16 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CNX65_RS04970 1ed52faa5d9317eb788f2937d59a9d37 261 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 182 260 1.6E-6 T 28-03-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 CNX65_RS04970 1ed52faa5d9317eb788f2937d59a9d37 261 SUPERFAMILY SSF102462 176 260 5.06E-16 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CNX65_RS03030 5a2e910a84222a95b752644d48ad4941 276 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 181 276 2.3E-26 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS03030 5a2e910a84222a95b752644d48ad4941 276 Gene3D G3DSA:1.10.1040.10 180 276 1.3E-29 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS03030 5a2e910a84222a95b752644d48ad4941 276 SUPERFAMILY SSF48179 180 276 6.12E-29 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS03030 5a2e910a84222a95b752644d48ad4941 276 Gene3D G3DSA:3.40.50.720 3 179 1.1E-44 T 28-03-2018 CNX65_RS03030 5a2e910a84222a95b752644d48ad4941 276 PIRSF PIRSF000105 2 276 1.4E-69 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CNX65_RS03030 5a2e910a84222a95b752644d48ad4941 276 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 178 3.9E-51 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS03030 5a2e910a84222a95b752644d48ad4941 276 SUPERFAMILY SSF51735 4 180 1.55E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19550 8b2a04333a1375e9a2a53bf2f40ba406 179 Gene3D G3DSA:2.30.110.10 18 177 4.1E-37 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS19550 8b2a04333a1375e9a2a53bf2f40ba406 179 SUPERFAMILY SSF50475 21 171 3.68E-39 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS19550 8b2a04333a1375e9a2a53bf2f40ba406 179 Pfam PF01613 Flavin reductase like domain 25 170 4.9E-33 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS19550 8b2a04333a1375e9a2a53bf2f40ba406 179 SMART SM00903 24 169 4.5E-42 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS11570 0ee091450d1b2b797c27486eff2655a2 374 Pfam PF01882 Protein of unknown function DUF58 189 263 9.3E-16 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 Pfam PF08532 Beta-galactosidase trimerisation domain 398 608 4.3E-59 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 Pfam PF08533 Beta-galactosidase C-terminal domain 618 676 3.9E-5 T 28-03-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 SUPERFAMILY SSF52317 395 608 8.7E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 PIRSF PIRSF001084 1 678 1.6E-238 T 28-03-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 Gene3D G3DSA:3.40.50.880 395 611 3.8E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 Gene3D G3DSA:2.60.40.1180 616 677 1.6E-7 T 28-03-2018 CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 Gene3D G3DSA:3.20.20.80 5 378 1.2E-82 T 28-03-2018 CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 Pfam PF02449 Beta-galactosidase 10 385 4.1E-142 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS09865 4c9ee003bdf9985dac12659ad299df53 679 SUPERFAMILY SSF51445 5 367 8.6E-105 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS33260 4bbb0397e58363e945d66c60c3510e2b 336 Gene3D G3DSA:3.30.420.40 1 124 2.1E-34 T 28-03-2018 CNX65_RS33260 4bbb0397e58363e945d66c60c3510e2b 336 Pfam PF02541 Ppx/GppA phosphatase family 17 305 9.7E-73 T 28-03-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 CNX65_RS33260 4bbb0397e58363e945d66c60c3510e2b 336 SUPERFAMILY SSF53067 2 125 1.77E-28 T 28-03-2018 CNX65_RS33260 4bbb0397e58363e945d66c60c3510e2b 336 Gene3D G3DSA:3.30.420.150 126 309 8.9E-39 T 28-03-2018 CNX65_RS33260 4bbb0397e58363e945d66c60c3510e2b 336 SUPERFAMILY SSF53067 129 306 5.61E-35 T 28-03-2018 CNX65_RS05905 576ce6ac7e9c7895891d71ccabcd5073 251 Pfam PF10105 Uncharacterized protein conserved in bacteria (DUF2344) 3 185 1.3E-50 T 28-03-2018 IPR018768 Domain of unknown function DUF2344 CNX65_RS05905 576ce6ac7e9c7895891d71ccabcd5073 251 TIGRFAM TIGR03936 sam_1_link_chp: radical SAM-linked protein 3 211 3.1E-56 T 28-03-2018 IPR018768 Domain of unknown function DUF2344 CNX65_RS05905 576ce6ac7e9c7895891d71ccabcd5073 251 Gene3D G3DSA:3.30.470.10 104 176 0.0023 T 28-03-2018 CNX65_RS11575 5b70252a94e794af18c06d73d6f2e164 555 Gene3D G3DSA:3.40.50.980 200 347 7.0E-33 T 28-03-2018 CNX65_RS11575 5b70252a94e794af18c06d73d6f2e164 555 Pfam PF13193 AMP-binding enzyme C-terminal domain 449 526 1.8E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS11575 5b70252a94e794af18c06d73d6f2e164 555 Gene3D G3DSA:3.40.50.980 33 199 2.0E-35 T 28-03-2018 CNX65_RS11575 5b70252a94e794af18c06d73d6f2e164 555 Pfam PF00501 AMP-binding enzyme 42 440 2.9E-80 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS11575 5b70252a94e794af18c06d73d6f2e164 555 Gene3D G3DSA:2.30.38.10 348 433 4.9E-23 T 28-03-2018 CNX65_RS11575 5b70252a94e794af18c06d73d6f2e164 555 Gene3D G3DSA:3.30.300.30 434 542 3.4E-21 T 28-03-2018 CNX65_RS11575 5b70252a94e794af18c06d73d6f2e164 555 SUPERFAMILY SSF56801 18 538 8.24E-135 T 28-03-2018 CNX65_RS19385 2fc39f711731aa040c236b694716a510 534 Gene3D G3DSA:1.10.287.950 31 319 7.0E-4 T 28-03-2018 CNX65_RS19385 2fc39f711731aa040c236b694716a510 534 Gene3D G3DSA:1.10.287.950 320 534 1.5E-42 T 28-03-2018 CNX65_RS19385 2fc39f711731aa040c236b694716a510 534 SUPERFAMILY SSF58104 239 532 1.31E-58 T 28-03-2018 CNX65_RS19385 2fc39f711731aa040c236b694716a510 534 SMART SM00304 219 271 1.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS19385 2fc39f711731aa040c236b694716a510 534 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 337 494 1.5E-29 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS19385 2fc39f711731aa040c236b694716a510 534 SMART SM00283 279 533 6.2E-40 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS19385 2fc39f711731aa040c236b694716a510 534 Pfam PF00672 HAMP domain 219 266 4.6E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 PRINTS PR00154 AMP-binding signature 449 460 9.2E-5 T 28-03-2018 IPR020459 AMP-binding CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 PRINTS PR00154 AMP-binding signature 461 469 9.2E-5 T 28-03-2018 IPR020459 AMP-binding CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 Pfam PF13193 AMP-binding enzyme C-terminal domain 717 786 4.0E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 Pfam PF00501 AMP-binding enzyme 321 709 2.1E-90 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 Gene3D G3DSA:3.40.50.980 311 459 3.2E-48 T 28-03-2018 CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 Gene3D G3DSA:3.30.300.30 703 796 7.7E-29 T 28-03-2018 CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 Gene3D G3DSA:3.40.50.980 460 615 1.4E-31 T 28-03-2018 CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 340 733 4.3E-119 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 SUPERFAMILY SSF52777 129 285 3.34E-6 T 28-03-2018 CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 ProSitePatterns PS00455 Putative AMP-binding domain signature. 454 465 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 SUPERFAMILY SSF56801 292 795 2.09E-140 T 28-03-2018 CNX65_RS18310 9361b91392579b877dcc143ed23a3854 796 Gene3D G3DSA:2.30.38.10 617 698 7.1E-25 T 28-03-2018 CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 SMART SM00418 20 106 9.0E-16 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 SUPERFAMILY SSF55729 119 275 6.45E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 Gene3D G3DSA:3.40.630.30 202 268 3.2E-14 T 28-03-2018 CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 Pfam PF13420 Acetyltransferase (GNAT) domain 121 269 4.3E-13 T 28-03-2018 CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 Pfam PF12840 Helix-turn-helix domain 20 79 5.8E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 Gene3D G3DSA:1.10.10.10 4 102 4.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 SUPERFAMILY SSF46785 13 90 1.58E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 22 37 4.6E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 71 4.6E-7 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19455 7813055edf02455335108556f2a28aa4 283 Gene3D G3DSA:3.40.630.30 113 201 1.4E-14 T 28-03-2018 CNX65_RS33710 aa0f467b4b46903ae80e82a81bc668ed 564 PRINTS PR01228 Eggshell protein signature 494 512 1.3E-5 T 28-03-2018 CNX65_RS33710 aa0f467b4b46903ae80e82a81bc668ed 564 PRINTS PR01228 Eggshell protein signature 422 437 1.3E-5 T 28-03-2018 CNX65_RS33710 aa0f467b4b46903ae80e82a81bc668ed 564 PRINTS PR01228 Eggshell protein signature 359 370 1.3E-5 T 28-03-2018 CNX65_RS33710 aa0f467b4b46903ae80e82a81bc668ed 564 PRINTS PR01228 Eggshell protein signature 449 459 1.3E-5 T 28-03-2018 CNX65_RS33710 aa0f467b4b46903ae80e82a81bc668ed 564 Pfam PF00823 PPE family 105 248 2.7E-9 T 28-03-2018 IPR000030 PPE family CNX65_RS33710 aa0f467b4b46903ae80e82a81bc668ed 564 SUPERFAMILY SSF140459 94 264 4.71E-10 T 28-03-2018 CNX65_RS33710 aa0f467b4b46903ae80e82a81bc668ed 564 Gene3D G3DSA:1.10.287.1060 108 199 1.3E-8 T 28-03-2018 CNX65_RS13525 6afad1200e8ede0b92834bead50e5708 167 Pfam PF04213 Htaa 17 162 4.8E-21 T 28-03-2018 IPR007331 Htaa CNX65_RS31020 5f5aa7ca962bc4ccbf4962a24b7bc98a 335 Gene3D G3DSA:1.10.40.50 266 334 5.4E-18 T 28-03-2018 CNX65_RS31020 5f5aa7ca962bc4ccbf4962a24b7bc98a 335 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 35 332 25.143 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CNX65_RS31020 5f5aa7ca962bc4ccbf4962a24b7bc98a 335 Gene3D G3DSA:3.40.50.300 113 265 3.1E-18 T 28-03-2018 CNX65_RS31020 5f5aa7ca962bc4ccbf4962a24b7bc98a 335 SUPERFAMILY SSF52540 115 287 5.7E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31020 5f5aa7ca962bc4ccbf4962a24b7bc98a 335 Pfam PF03193 RsgA GTPase 97 265 1.3E-41 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CNX65_RS31020 5f5aa7ca962bc4ccbf4962a24b7bc98a 335 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 72 326 5.4E-44 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CNX65_RS29240 27b556f8385f1b16fcbb1a1d0d5b090b 95 Gene3D G3DSA:3.30.70.100 1 93 2.7E-27 T 28-03-2018 CNX65_RS29240 27b556f8385f1b16fcbb1a1d0d5b090b 95 SUPERFAMILY SSF54975 7 93 4.36E-24 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CNX65_RS29240 27b556f8385f1b16fcbb1a1d0d5b090b 95 Pfam PF00708 Acylphosphatase 11 92 8.3E-22 T 28-03-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CNX65_RS29240 27b556f8385f1b16fcbb1a1d0d5b090b 95 ProSitePatterns PS00150 Acylphosphatase signature 1. 14 24 - T 28-03-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 CNX65_RS21680 c512b2f53df2d9cdbd64dcf375349736 290 Gene3D G3DSA:1.10.260.40 11 97 1.8E-12 T 28-03-2018 CNX65_RS21680 c512b2f53df2d9cdbd64dcf375349736 290 SUPERFAMILY SSF47413 36 88 2.12E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS21680 c512b2f53df2d9cdbd64dcf375349736 290 SMART SM00530 16 89 1.2E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS21680 c512b2f53df2d9cdbd64dcf375349736 290 Pfam PF13560 Helix-turn-helix domain 12 92 8.8E-15 T 28-03-2018 CNX65_RS32125 e40cd1b0173383e16eacc257d03e7ee6 147 SUPERFAMILY SSF55729 2 132 4.73E-31 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS32125 e40cd1b0173383e16eacc257d03e7ee6 147 Gene3D G3DSA:3.40.630.30 1 147 3.9E-34 T 28-03-2018 CNX65_RS32125 e40cd1b0173383e16eacc257d03e7ee6 147 Pfam PF00583 Acetyltransferase (GNAT) family 18 120 6.7E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS32125 e40cd1b0173383e16eacc257d03e7ee6 147 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 10 140 2.0E-34 T 28-03-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 CNX65_RS26720 d551ded6186c971de4603411cccf9acd 317 SUPERFAMILY SSF51430 3 316 1.31E-68 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS26720 d551ded6186c971de4603411cccf9acd 317 Gene3D G3DSA:3.20.20.100 1 317 3.2E-65 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS26720 d551ded6186c971de4603411cccf9acd 317 Pfam PF00248 Aldo/keto reductase family 14 316 2.1E-48 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS13570 bb47a4226a62e0c7297f57c3609af64b 613 SUPERFAMILY SSF103473 248 420 4.19E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13570 bb47a4226a62e0c7297f57c3609af64b 613 SUPERFAMILY SSF103473 473 503 4.19E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13570 bb47a4226a62e0c7297f57c3609af64b 613 SUPERFAMILY SSF103473 5 198 4.19E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13570 bb47a4226a62e0c7297f57c3609af64b 613 Pfam PF07690 Major Facilitator Superfamily 18 410 1.2E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS13570 bb47a4226a62e0c7297f57c3609af64b 613 Gene3D G3DSA:1.20.1250.20 7 197 3.9E-31 T 28-03-2018 CNX65_RS13570 bb47a4226a62e0c7297f57c3609af64b 613 Gene3D G3DSA:1.20.1250.20 252 515 6.4E-22 T 28-03-2018 CNX65_RS19580 123571d1c6bc6ebfa5e2cec223ba0e1d 175 SUPERFAMILY SSF55961 13 136 2.08E-20 T 28-03-2018 CNX65_RS19580 123571d1c6bc6ebfa5e2cec223ba0e1d 175 Gene3D G3DSA:3.30.530.20 1 144 1.9E-21 T 28-03-2018 IPR023393 START-like domain CNX65_RS19580 123571d1c6bc6ebfa5e2cec223ba0e1d 175 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 13 131 9.6E-20 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CNX65_RS11700 789f3925a9a593412b13129b76098694 334 SUPERFAMILY SSF51658 8 318 5.76E-59 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS11700 789f3925a9a593412b13129b76098694 334 Pfam PF01261 Xylose isomerase-like TIM barrel 22 273 2.8E-36 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS11700 789f3925a9a593412b13129b76098694 334 Pfam PF07582 AP endonuclease family 2 C terminus 275 329 2.6E-24 T 28-03-2018 IPR011418 AP endonuclease, family 2, C-terminal CNX65_RS11700 789f3925a9a593412b13129b76098694 334 Gene3D G3DSA:3.20.20.150 1 322 7.9E-61 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF52151 271 371 2.14E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF52151 84 207 2.14E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.30.70.250 1612 1654 3.5E-11 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.366.10 1655 1775 1.8E-21 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.366.10 261 386 2.4E-23 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM00825 Beta-ketoacyl synthase 2251 2501 8.6E-18 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF08659 KR domain 2880 3064 1.0E-44 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF08659 KR domain 2013 2183 7.6E-36 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF51735 2009 2223 2.05E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:1.10.1200.10 3168 3258 5.8E-19 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2880 3066 2.2E-33 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2013 2185 1.1E-11 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF47336 487 585 7.33E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF55048 205 269 2.09E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 1488 1770 1.4E-78 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 86 380 1.7E-87 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF53901 1159 1343 3.36E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF51735 2880 3068 5.07E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00698 Acyl transferase domain 1490 1789 2.3E-59 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00698 Acyl transferase domain 85 399 2.4E-66 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00698 Acyl transferase domain 902 1005 3.9E-22 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF53901 2379 2501 1.08E-9 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF53901 2251 2401 1.2E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.47.10 567 723 6.9E-23 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.366.10 880 1023 1.7E-31 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.30.70.250 214 260 3.5E-15 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.47.10 724 746 0.0086 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1268 1317 1.5E-7 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 1159 1262 4.4E-14 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 2258 2386 3.8E-27 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 603 656 2.4E-9 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.50.720 1996 2256 8.9E-29 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.47.10 2257 2508 2.4E-31 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.50.720 2876 3167 5.2E-35 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM00823 Phosphopantetheine attachment site 3183 3252 2.0E-19 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM00823 Phosphopantetheine attachment site 490 561 1.8E-15 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF55048 1600 1661 4.84E-7 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00550 Phosphopantetheine attachment site 508 556 2.6E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF00550 Phosphopantetheine attachment site 3185 3248 1.8E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF47336 3180 3260 1.57E-18 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF52151 1474 1601 6.28E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF52151 1662 1754 6.28E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:1.10.1200.10 467 566 2.6E-14 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.366.10 83 213 1.5E-30 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.366.10 1473 1611 1.4E-34 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF53901 568 737 5.76E-26 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.366.10 1024 1089 6.8E-6 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SMART SM01294 3184 3248 0.0047 T 28-03-2018 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Gene3D G3DSA:3.40.47.10 1149 1344 3.0E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF51735 2733 2868 1.18E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 2468 2559 1.4E-9 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF52151 890 1068 1.86E-27 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21825 ea971ff1e85786d74530e02cf6952576 3329 SUPERFAMILY SSF51735 1827 2001 2.17E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22915 6567f368773f7800466c285dcc6af083 427 Pfam PF13416 Bacterial extracellular solute-binding protein 61 354 7.2E-16 T 28-03-2018 CNX65_RS22915 6567f368773f7800466c285dcc6af083 427 Gene3D G3DSA:3.40.190.10 156 359 1.4E-25 T 28-03-2018 CNX65_RS22915 6567f368773f7800466c285dcc6af083 427 SUPERFAMILY SSF53850 25 405 1.09E-37 T 28-03-2018 CNX65_RS03830 f6c22bf69a4185382e15c340d044fb94 512 Gene3D G3DSA:3.40.50.1820 24 335 1.5E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03830 f6c22bf69a4185382e15c340d044fb94 512 SMART SM00939 306 507 1.7E-12 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS03830 f6c22bf69a4185382e15c340d044fb94 512 Pfam PF02129 X-Pro dipeptidyl-peptidase (S15 family) 57 287 1.0E-27 T 28-03-2018 IPR000383 Xaa-Pro dipeptidyl-peptidase-like domain GO:0016787 CNX65_RS03830 f6c22bf69a4185382e15c340d044fb94 512 Pfam PF08530 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain 318 489 3.0E-5 T 28-03-2018 IPR013736 Xaa-Pro dipeptidyl-peptidase, C-terminal GO:0008239 CNX65_RS03830 f6c22bf69a4185382e15c340d044fb94 512 SUPERFAMILY SSF49785 334 490 4.68E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS03830 f6c22bf69a4185382e15c340d044fb94 512 Gene3D G3DSA:2.60.120.260 336 511 4.8E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS03830 f6c22bf69a4185382e15c340d044fb94 512 SUPERFAMILY SSF53474 27 325 3.05E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30245 746bfbf87b317cc03eeb0bd5c7a8c822 216 SUPERFAMILY SSF55821 4 208 1.59E-55 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CNX65_RS30245 746bfbf87b317cc03eeb0bd5c7a8c822 216 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 16 207 1.6E-59 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CNX65_RS30245 746bfbf87b317cc03eeb0bd5c7a8c822 216 Gene3D G3DSA:3.90.870.10 1 213 1.1E-66 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CNX65_RS30245 746bfbf87b317cc03eeb0bd5c7a8c822 216 Pfam PF01300 Telomere recombination 23 197 9.0E-46 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 Pfam PF00501 AMP-binding enzyme 21 425 1.4E-102 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 Gene3D G3DSA:3.40.50.980 183 337 1.9E-38 T 28-03-2018 CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 Gene3D G3DSA:2.30.38.10 338 418 8.9E-28 T 28-03-2018 CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 Gene3D G3DSA:3.30.300.30 420 523 1.4E-24 T 28-03-2018 CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 Gene3D G3DSA:3.40.50.980 12 182 1.3E-41 T 28-03-2018 CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 434 507 1.2E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS23330 b57010f23b85801465f0d4f126faeafd 524 SUPERFAMILY SSF56801 14 519 1.83E-144 T 28-03-2018 CNX65_RS08375 1828fea439349856042d52f7ed5f4db0 347 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 252 317 2.7E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS08375 1828fea439349856042d52f7ed5f4db0 347 SMART SM00382 54 250 7.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08375 1828fea439349856042d52f7ed5f4db0 347 Pfam PF00005 ABC transporter 46 200 5.7E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS08375 1828fea439349856042d52f7ed5f4db0 347 Gene3D G3DSA:3.40.50.300 12 346 2.6E-72 T 28-03-2018 CNX65_RS08375 1828fea439349856042d52f7ed5f4db0 347 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 339 4.0E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS08375 1828fea439349856042d52f7ed5f4db0 347 SUPERFAMILY SSF52540 55 325 5.44E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08375 1828fea439349856042d52f7ed5f4db0 347 ProSitePatterns PS00211 ABC transporters family signature. 173 187 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 SMART SM00829 8 342 0.0016 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 SUPERFAMILY SSF51735 148 311 5.7E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 Pfam PF00107 Zinc-binding dehydrogenase 178 305 1.7E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 Gene3D G3DSA:3.90.180.10 1 162 5.6E-39 T 28-03-2018 CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 SUPERFAMILY SSF50129 2 168 2.43E-46 T 28-03-2018 IPR011032 GroES-like CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 Pfam PF13823 Alcohol dehydrogenase GroES-associated 7 23 1.1E-6 T 28-03-2018 IPR027399 Alcohol dehydrogenase GroES-associated CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 Gene3D G3DSA:3.40.50.10730 163 305 1.0E-24 T 28-03-2018 CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS05180 ea5c60895e49927094df44707971a3e6 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 127 2.7E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS29750 f3a45bcad82d4b03f5118d3225adefb2 362 SUPERFAMILY SSF52402 1 243 7.94E-47 T 28-03-2018 CNX65_RS29750 f3a45bcad82d4b03f5118d3225adefb2 362 Gene3D G3DSA:2.30.30.280 207 271 1.9E-13 T 28-03-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 Reactome: R-HSA-6787450 CNX65_RS29750 f3a45bcad82d4b03f5118d3225adefb2 362 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 1 358 35.931 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CNX65_RS29750 f3a45bcad82d4b03f5118d3225adefb2 362 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 1 344 6.2E-81 T 28-03-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 Reactome: R-HSA-6787450 CNX65_RS29750 f3a45bcad82d4b03f5118d3225adefb2 362 Gene3D G3DSA:2.40.30.10 272 362 1.5E-15 T 28-03-2018 CNX65_RS29750 f3a45bcad82d4b03f5118d3225adefb2 362 Gene3D G3DSA:3.40.50.620 1 206 1.8E-55 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS29750 f3a45bcad82d4b03f5118d3225adefb2 362 Pfam PF03054 tRNA methyl transferase 1 355 6.1E-108 T 28-03-2018 CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 Gene3D G3DSA:3.30.420.40 70 191 2.9E-28 T 28-03-2018 CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 Pfam PF00480 ROK family 76 383 7.4E-56 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 SUPERFAMILY SSF46785 6 68 1.16E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 Gene3D G3DSA:1.10.10.10 3 69 1.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 Gene3D G3DSA:3.30.420.40 192 389 9.5E-53 T 28-03-2018 CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 SUPERFAMILY SSF53067 75 385 2.22E-54 T 28-03-2018 CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 ProSitePatterns PS01125 ROK family signature. 206 233 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS11690 7f2fcabc49bba8cc3c56a06d2aef2f08 389 Pfam PF12802 MarR family 8 59 1.1E-6 T 28-03-2018 CNX65_RS10365 961e451888772733f1e8e3a8a74a6729 188 SUPERFAMILY SSF56349 50 180 2.83E-27 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS10365 961e451888772733f1e8e3a8a74a6729 188 Pfam PF00589 Phage integrase family 52 172 3.0E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS10365 961e451888772733f1e8e3a8a74a6729 188 Gene3D G3DSA:1.10.443.10 27 180 1.6E-28 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 Hamap MF_00109 Shikimate kinase [aroK]. 2 167 24.725 T 28-03-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 PRINTS PR01100 Shikimate kinase family signature 75 84 1.8E-12 T 28-03-2018 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 PRINTS PR01100 Shikimate kinase family signature 57 65 1.8E-12 T 28-03-2018 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 PRINTS PR01100 Shikimate kinase family signature 5 20 1.8E-12 T 28-03-2018 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 PRINTS PR01100 Shikimate kinase family signature 95 112 1.8E-12 T 28-03-2018 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 PRINTS PR01100 Shikimate kinase family signature 29 42 1.8E-12 T 28-03-2018 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 SUPERFAMILY SSF52540 2 164 2.52E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 Gene3D G3DSA:3.40.50.300 1 170 4.7E-29 T 28-03-2018 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 Pfam PF01202 Shikimate kinase 11 164 9.4E-38 T 28-03-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CNX65_RS26150 f3fb41d4bc9e67155d0024036eba74e3 171 ProSitePatterns PS01128 Shikimate kinase signature. 58 83 - T 28-03-2018 IPR023000 Shikimate kinase, conserved site KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 ProSitePatterns PS01143 Ribosomal protein L31 signature. 49 70 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 Hamap MF_00502 50S ribosomal protein L31 type B [rpmE2]. 1 81 25.512 T 28-03-2018 IPR027493 Ribosomal protein L31 type B GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 80 8.7E-23 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 Pfam PF01197 Ribosomal protein L31 2 79 5.8E-32 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 PRINTS PR01249 Ribosomal protein L31 signature 60 78 8.7E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 PRINTS PR01249 Ribosomal protein L31 signature 2 19 8.7E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 PRINTS PR01249 Ribosomal protein L31 signature 45 60 8.7E-19 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS22105 7fccc24e8db7af8cf68c1108488ae271 83 SUPERFAMILY SSF143800 2 79 3.1E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS25900 ec5bdc99c331527d1dc5441d390ecbc6 171 SUPERFAMILY SSF50022 74 168 3.67E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS25900 ec5bdc99c331527d1dc5441d390ecbc6 171 Gene3D G3DSA:2.102.10.10 66 171 1.1E-19 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS25900 ec5bdc99c331527d1dc5441d390ecbc6 171 Pfam PF00355 Rieske [2Fe-2S] domain 80 155 1.6E-12 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS32620 485c3622b7766be8714baa26d17e617b 148 Pfam PF13452 N-terminal half of MaoC dehydratase 7 137 1.1E-31 T 28-03-2018 CNX65_RS32620 485c3622b7766be8714baa26d17e617b 148 PIRSF PIRSF018072 2 148 1.1E-56 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CNX65_RS32620 485c3622b7766be8714baa26d17e617b 148 SUPERFAMILY SSF54637 7 147 3.59E-38 T 28-03-2018 IPR029069 HotDog domain CNX65_RS32620 485c3622b7766be8714baa26d17e617b 148 Hamap MF_00799 UPF0336 protein . 1 148 32.584 T 28-03-2018 IPR016709 Uncharacterised protein family UPF0336 CNX65_RS32620 485c3622b7766be8714baa26d17e617b 148 Gene3D G3DSA:3.10.129.10 4 148 4.4E-38 T 28-03-2018 CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 Pfam PF00106 short chain dehydrogenase 8 198 1.7E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 SUPERFAMILY SSF51735 2 260 3.42E-68 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 83 94 3.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 179 196 3.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 3.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 3.7E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 194 0.0025 T 28-03-2018 CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 2.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS16310 cd5e20cfdd1c96217599a27801a3a937 341 Gene3D G3DSA:3.40.50.720 1 268 1.5E-58 T 28-03-2018 CNX65_RS11460 2127506f0233dd2692cac59c3669d585 115 Pfam PF02416 mttA/Hcf106 family 4 54 6.4E-18 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CNX65_RS11460 2127506f0233dd2692cac59c3669d585 115 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 1 86 20.573 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CNX65_RS11460 2127506f0233dd2692cac59c3669d585 115 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 4 49 3.2E-17 T 28-03-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 CNX65_RS23470 4cdcd89c875e47546610379aef6b754e 326 Gene3D G3DSA:3.40.50.300 3 314 4.0E-70 T 28-03-2018 CNX65_RS23470 4cdcd89c875e47546610379aef6b754e 326 Pfam PF00005 ABC transporter 35 185 2.4E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS23470 4cdcd89c875e47546610379aef6b754e 326 SUPERFAMILY SSF52540 9 257 8.91E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23470 4cdcd89c875e47546610379aef6b754e 326 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 278 5.6E-9 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS23470 4cdcd89c875e47546610379aef6b754e 326 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS23470 4cdcd89c875e47546610379aef6b754e 326 SMART SM00382 43 235 6.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS27015 aeea88a0ff6ab5f4f848f0037aa6fdaa 193 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 21 181 1.3E-30 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CNX65_RS27015 aeea88a0ff6ab5f4f848f0037aa6fdaa 193 PIRSF PIRSF019345 5 193 2.2E-54 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CNX65_RS27015 aeea88a0ff6ab5f4f848f0037aa6fdaa 193 Pfam PF04079 Segregation and condensation complex subunit ScpB 23 180 4.0E-51 T 28-03-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 CNX65_RS27015 aeea88a0ff6ab5f4f848f0037aa6fdaa 193 Gene3D G3DSA:1.10.10.10 98 188 2.8E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27015 aeea88a0ff6ab5f4f848f0037aa6fdaa 193 Gene3D G3DSA:1.10.10.10 8 97 5.7E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27015 aeea88a0ff6ab5f4f848f0037aa6fdaa 193 SUPERFAMILY SSF46785 17 94 1.78E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27015 aeea88a0ff6ab5f4f848f0037aa6fdaa 193 SUPERFAMILY SSF46785 98 171 1.56E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30100 3bcfc4c5d01f567b9b0b7542df331847 562 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 161 186 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CNX65_RS30100 3bcfc4c5d01f567b9b0b7542df331847 562 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 46 461 1.9E-80 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS30100 3bcfc4c5d01f567b9b0b7542df331847 562 Pfam PF00474 Sodium:solute symporter family 46 461 5.9E-55 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS13985 a6512d47b6d20af3e572e5b2807a2409 256 SUPERFAMILY SSF52540 20 237 5.99E-70 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13985 a6512d47b6d20af3e572e5b2807a2409 256 SMART SM00382 47 233 5.3E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13985 a6512d47b6d20af3e572e5b2807a2409 256 Pfam PF00005 ABC transporter 38 184 2.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13985 a6512d47b6d20af3e572e5b2807a2409 256 Gene3D G3DSA:3.40.50.300 15 250 2.1E-62 T 28-03-2018 CNX65_RS13985 a6512d47b6d20af3e572e5b2807a2409 256 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS34615 01e9b8d24e7ba652cefe4f7cb7244451 124 Gene3D G3DSA:2.30.22.10 65 122 2.1E-11 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CNX65_RS34615 01e9b8d24e7ba652cefe4f7cb7244451 124 SUPERFAMILY SSF51064 67 122 1.12E-7 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CNX65_RS34615 01e9b8d24e7ba652cefe4f7cb7244451 124 Pfam PF01025 GrpE 55 121 2.6E-7 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34435 6ec24965f2aca777647660a2a51a7a08 163 SUPERFAMILY SSF46955 75 121 1.04E-6 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS34435 6ec24965f2aca777647660a2a51a7a08 163 Gene3D G3DSA:1.10.10.60 21 88 5.8E-5 T 28-03-2018 CNX65_RS34435 6ec24965f2aca777647660a2a51a7a08 163 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 76 122 3.7E-14 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CNX65_RS34435 6ec24965f2aca777647660a2a51a7a08 163 Pfam PF12728 Helix-turn-helix domain 75 123 1.5E-11 T 28-03-2018 CNX65_RS34435 6ec24965f2aca777647660a2a51a7a08 163 Gene3D G3DSA:1.10.10.10 89 134 9.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01580 7bd65eb7f6d20a2f0c59d542f5a68790 167 Pfam PF00719 Inorganic pyrophosphatase 5 157 4.2E-52 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CNX65_RS01580 7bd65eb7f6d20a2f0c59d542f5a68790 167 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 1 158 32.045 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CNX65_RS01580 7bd65eb7f6d20a2f0c59d542f5a68790 167 SUPERFAMILY SSF50324 3 158 4.71E-56 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CNX65_RS01580 7bd65eb7f6d20a2f0c59d542f5a68790 167 Gene3D G3DSA:3.90.80.10 1 164 6.5E-53 T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CNX65_RS01580 7bd65eb7f6d20a2f0c59d542f5a68790 167 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 52 58 - T 28-03-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 SUPERFAMILY SSF48264 18 396 9.95E-104 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00385 P450 superfamily signature 235 252 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00385 P450 superfamily signature 270 281 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00385 P450 superfamily signature 347 358 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00385 P450 superfamily signature 338 347 3.6E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 347 358 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 87 98 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 189 211 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 151 166 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 289 316 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 317 332 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 338 347 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 134 150 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 PRINTS PR00359 B-class P450 signature 270 281 3.7E-62 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 Pfam PF00067 Cytochrome P450 184 367 1.5E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS14130 94a9a1362b68a58058704e15fe607a68 401 Gene3D G3DSA:1.10.630.10 3 396 2.6E-84 T 28-03-2018 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 Gene3D G3DSA:1.10.601.10 4 156 1.2E-60 T 28-03-2018 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 111 124 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 280 306 - T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 SUPERFAMILY SSF88659 160 233 2.62E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 Pfam PF04545 Sigma-70, region 4 257 307 4.1E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 Pfam PF04542 Sigma-70 region 2 87 156 9.5E-19 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 Gene3D G3DSA:1.10.10.10 249 319 2.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 Pfam PF00140 Sigma-70 factor, region 1.2 23 56 7.8E-13 T 28-03-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 SUPERFAMILY SSF88946 23 157 8.79E-48 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 PRINTS PR00046 Major sigma-70 factor signature 259 271 1.3E-22 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 PRINTS PR00046 Major sigma-70 factor signature 280 295 1.3E-22 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 PRINTS PR00046 Major sigma-70 factor signature 295 306 1.3E-22 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 PRINTS PR00046 Major sigma-70 factor signature 111 124 1.3E-22 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 PRINTS PR00046 Major sigma-70 factor signature 135 143 1.3E-22 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 SUPERFAMILY SSF88659 217 312 1.6E-22 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 83 308 5.9E-34 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 Gene3D G3DSA:1.10.10.10 157 209 9.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09485 7e027b2049b6ec08f23a088fccc76edd 320 Pfam PF04539 Sigma-70 region 3 166 241 5.9E-19 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SUPERFAMILY SSF50249 45 198 1.74E-32 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Pfam PF01588 Putative tRNA binding domain 47 148 1.1E-17 T 28-03-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Pfam PF03483 B3/4 domain 216 385 2.0E-65 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SMART SM00896 731 824 4.9E-38 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Gene3D G3DSA:3.30.930.10 493 720 4.6E-35 T 28-03-2018 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Pfam PF03484 tRNA synthetase B5 domain 409 478 2.6E-11 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Gene3D G3DSA:2.40.50.140 35 164 6.9E-44 T 28-03-2018 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SMART SM00873 216 389 1.6E-84 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Gene3D G3DSA:3.30.70.380 728 824 7.7E-23 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SUPERFAMILY SSF54991 730 824 3.66E-24 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SMART SM00874 405 478 1.6E-19 T 28-03-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 818 39.375 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 2 824 2.0E-172 T 28-03-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SUPERFAMILY SSF56037 202 401 1.52E-67 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Pfam PF03147 Ferredoxin-fold anticodon binding domain 731 824 1.1E-22 T 28-03-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Gene3D G3DSA:3.30.56.10 404 482 2.6E-15 T 28-03-2018 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SUPERFAMILY SSF55681 620 719 6.46E-41 T 28-03-2018 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SUPERFAMILY SSF55681 474 590 6.46E-41 T 28-03-2018 CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 SUPERFAMILY SSF46955 407 482 6.32E-13 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS27215 4a3bcc97ccf630f5b8188961ead74692 825 Gene3D G3DSA:3.50.40.10 200 400 1.3E-74 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CNX65_RS10525 58f428e2e5f4b009217c5d207f416315 208 Gene3D G3DSA:1.20.1260.10 52 207 7.4E-47 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS10525 58f428e2e5f4b009217c5d207f416315 208 Pfam PF03713 Domain of unknown function (DUF305) 60 206 2.4E-45 T 28-03-2018 IPR005183 Domain of unknown function DUF305 CNX65_RS02670 1979da26c28e46d94878b3525591ac62 198 Gene3D G3DSA:1.10.357.10 64 196 3.0E-11 T 28-03-2018 CNX65_RS02670 1979da26c28e46d94878b3525591ac62 198 Gene3D G3DSA:1.10.10.60 4 63 3.8E-10 T 28-03-2018 CNX65_RS02670 1979da26c28e46d94878b3525591ac62 198 SUPERFAMILY SSF48498 111 193 8.56E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS02670 1979da26c28e46d94878b3525591ac62 198 SUPERFAMILY SSF46689 16 83 2.72E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS02670 1979da26c28e46d94878b3525591ac62 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 61 1.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 SUPERFAMILY SSF51445 66 367 2.21E-72 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 Gene3D G3DSA:3.20.20.300 37 365 3.6E-80 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 71 343 3.2E-54 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 SUPERFAMILY SSF52279 378 619 3.92E-22 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 378 619 2.5E-23 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 113 132 3.9E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 90 106 3.9E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 268 286 3.9E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 159 175 3.9E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 PRINTS PR00133 Glycosyl hydrolase family 3 signature 198 214 3.9E-16 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 Gene3D G3DSA:3.40.50.1700 366 620 1.3E-40 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS22930 0d812f71461637e1f89877c604a7c07d 746 Gene3D G3DSA:2.60.40.10 625 738 1.5E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS33575 9d7a836e31987de402d3da7c2a2de816 59 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 7 52 3.4E-8 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CNX65_RS33575 9d7a836e31987de402d3da7c2a2de816 59 Pfam PF12728 Helix-turn-helix domain 6 52 4.4E-13 T 28-03-2018 CNX65_RS33575 9d7a836e31987de402d3da7c2a2de816 59 Gene3D G3DSA:1.10.10.10 6 58 7.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33575 9d7a836e31987de402d3da7c2a2de816 59 SUPERFAMILY SSF46955 4 53 6.41E-10 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS08245 37ae5d0a932569b4ead61d99a449b109 560 Gene3D G3DSA:2.80.10.50 4 478 3.1E-10 T 28-03-2018 CNX65_RS08245 37ae5d0a932569b4ead61d99a449b109 560 SMART SM00458 434 560 1.2E-27 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS08245 37ae5d0a932569b4ead61d99a449b109 560 Gene3D G3DSA:4.10.1090.10 479 521 9.4E-11 T 28-03-2018 CNX65_RS08245 37ae5d0a932569b4ead61d99a449b109 560 Pfam PF16483 Beta-1,3-glucanase 37 394 5.1E-103 T 28-03-2018 IPR032477 Beta-1,3-glucanase, N-terminal KEGG: 00500+3.2.1.39 CNX65_RS08245 37ae5d0a932569b4ead61d99a449b109 560 Gene3D G3DSA:2.80.10.50 522 560 2.1E-11 T 28-03-2018 CNX65_RS08245 37ae5d0a932569b4ead61d99a449b109 560 SUPERFAMILY SSF50370 436 558 3.54E-32 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS08245 37ae5d0a932569b4ead61d99a449b109 560 Pfam PF00652 Ricin-type beta-trefoil lectin domain 437 557 5.9E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 90 4.1E-29 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 Pfam PF01479 S4 domain 92 138 1.6E-20 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 Gene3D G3DSA:1.10.1050.10 140 201 1.4E-10 T 28-03-2018 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 SMART SM00363 91 153 4.4E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 SMART SM01390 3 90 6.5E-43 T 28-03-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 SUPERFAMILY SSF55174 3 201 9.03E-66 T 28-03-2018 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 Gene3D G3DSA:1.10.1050.10 1 95 5.5E-40 T 28-03-2018 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 ProSitePatterns PS00632 Ribosomal protein S4 signature. 89 113 - T 28-03-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 Gene3D G3DSA:3.10.290.10 96 139 4.3E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 201 34.828 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CNX65_RS32305 6c7bb98370a86288a2c819fdb049cd10 201 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 201 2.9E-79 T 28-03-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 CNX65_RS24370 fb4fdcea958be5617a14e631521269db 243 Pfam PF01975 Survival protein SurE 4 175 9.5E-40 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CNX65_RS24370 fb4fdcea958be5617a14e631521269db 243 Gene3D G3DSA:3.40.1210.10 1 240 1.4E-50 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CNX65_RS24370 fb4fdcea958be5617a14e631521269db 243 SUPERFAMILY SSF64167 1 233 3.14E-45 T 28-03-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 CNX65_RS09045 4060bb90acfbdac7c524ef19a4b4483e 106 Gene3D G3DSA:1.10.10.10 1 100 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09045 4060bb90acfbdac7c524ef19a4b4483e 106 SMART SM00418 2 84 1.3E-21 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS09045 4060bb90acfbdac7c524ef19a4b4483e 106 SUPERFAMILY SSF46785 3 96 5.45E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09045 4060bb90acfbdac7c524ef19a4b4483e 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 3.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS09045 4060bb90acfbdac7c524ef19a4b4483e 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 4 19 3.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS09045 4060bb90acfbdac7c524ef19a4b4483e 106 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 55 70 3.3E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS09045 4060bb90acfbdac7c524ef19a4b4483e 106 Pfam PF01022 Bacterial regulatory protein, arsR family 9 57 3.2E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Pfam PF00550 Phosphopantetheine attachment site 947 1010 1.1E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 SUPERFAMILY SSF56801 409 950 6.8E-137 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 SUPERFAMILY SSF52777 173 418 6.45E-42 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 SMART SM00823 Phosphopantetheine attachment site 945 1014 9.4E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 SUPERFAMILY SSF47336 939 1010 3.01E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Pfam PF13193 AMP-binding enzyme C-terminal domain 841 915 5.9E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 ProSitePatterns PS00455 Putative AMP-binding domain signature. 584 595 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Gene3D G3DSA:3.30.559.10 2 177 7.1E-25 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Gene3D G3DSA:1.10.1200.10 951 1017 4.2E-18 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Gene3D G3DSA:3.30.300.30 828 950 3.5E-28 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Gene3D G3DSA:2.30.38.10 745 823 5.1E-25 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Pfam PF00501 AMP-binding enzyme 453 833 1.0E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 SUPERFAMILY SSF52777 8 158 5.34E-30 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Gene3D G3DSA:3.40.50.980 588 737 1.4E-40 T 28-03-2018 CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 470 856 2.8E-113 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Pfam PF00668 Condensation domain 10 424 1.2E-50 T 28-03-2018 IPR001242 Condensation domain CNX65_RS15310 38454f8e39a7ab4dee9541e197f1b804 1023 Gene3D G3DSA:3.40.50.980 442 587 6.3E-36 T 28-03-2018 CNX65_RS15420 c4a34fa5841f945f7e4e8d893c91964a 243 Pfam PF02754 Cysteine-rich domain 3 83 1.7E-16 T 28-03-2018 IPR004017 Cysteine-rich domain CNX65_RS15420 c4a34fa5841f945f7e4e8d893c91964a 243 Pfam PF02754 Cysteine-rich domain 134 218 1.2E-14 T 28-03-2018 IPR004017 Cysteine-rich domain CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 4 160 9.7E-44 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 Pfam PF04542 Sigma-70 region 2 9 74 2.9E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 Gene3D G3DSA:1.10.1740.10 2 71 1.9E-10 T 28-03-2018 CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 6 158 8.4E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 SUPERFAMILY SSF88659 94 157 2.43E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 Pfam PF08281 Sigma-70, region 4 102 155 1.2E-18 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 SUPERFAMILY SSF88946 5 80 7.85E-11 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS18020 10eb183842804d68a4ea9507df7b1812 167 Gene3D G3DSA:1.10.10.10 72 161 1.6E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 SMART SM00421 999 1056 4.2E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 ProSitePatterns PS00622 LuxR-type HTH domain signature. 1016 1043 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Gene3D G3DSA:1.10.10.10 404 488 1.4E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Pfam PF00196 Bacterial regulatory proteins, luxR family 1002 1052 3.8E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 SUPERFAMILY SSF46894 995 1052 4.08E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1002 1016 8.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1016 1032 8.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1032 1044 8.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 SUPERFAMILY SSF52540 268 347 3.1E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 SUPERFAMILY SSF52540 164 221 3.1E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 SUPERFAMILY SSF48452 711 839 9.96E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Pfam PF13191 AAA ATPase domain 170 316 3.4E-11 T 28-03-2018 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Gene3D G3DSA:1.25.40.10 648 777 0.01 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Gene3D G3DSA:1.25.40.10 778 1008 1.4E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Gene3D G3DSA:1.25.40.10 489 583 0.091 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Gene3D G3DSA:1.10.10.10 1009 1060 4.5E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16540 b4b17a52d14d0b837933191a5906ae84 1062 Gene3D G3DSA:3.40.50.300 158 384 1.8E-6 T 28-03-2018 CNX65_RS28060 d629982c12d0d8ed8fbf5e53e01c4199 519 SUPERFAMILY SSF53850 37 498 1.99E-105 T 28-03-2018 CNX65_RS28060 d629982c12d0d8ed8fbf5e53e01c4199 519 Gene3D G3DSA:3.10.105.10 284 478 7.8E-40 T 28-03-2018 CNX65_RS28060 d629982c12d0d8ed8fbf5e53e01c4199 519 Gene3D G3DSA:3.40.190.10 156 283 2.3E-29 T 28-03-2018 CNX65_RS28060 d629982c12d0d8ed8fbf5e53e01c4199 519 Gene3D G3DSA:3.90.76.10 56 155 8.1E-25 T 28-03-2018 CNX65_RS28060 d629982c12d0d8ed8fbf5e53e01c4199 519 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 78 420 4.3E-67 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS28060 d629982c12d0d8ed8fbf5e53e01c4199 519 PIRSF PIRSF002741 4 511 2.7E-79 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS05030 6ed433a18997b2cc1fe604037b21e6a9 189 SUPERFAMILY SSF52499 3 181 1.15E-43 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS05030 6ed433a18997b2cc1fe604037b21e6a9 189 Gene3D G3DSA:3.40.50.850 2 182 6.1E-55 T 28-03-2018 CNX65_RS05030 6ed433a18997b2cc1fe604037b21e6a9 189 Pfam PF00857 Isochorismatase family 4 181 4.6E-29 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS29760 876262b12f81c71580448959192b0631 441 SUPERFAMILY SSF103473 11 194 2.09E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS29760 876262b12f81c71580448959192b0631 441 SUPERFAMILY SSF103473 234 431 2.09E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS29760 876262b12f81c71580448959192b0631 441 Gene3D G3DSA:1.20.1250.20 246 434 1.2E-10 T 28-03-2018 CNX65_RS29760 876262b12f81c71580448959192b0631 441 Gene3D G3DSA:1.20.1250.20 6 196 6.4E-31 T 28-03-2018 CNX65_RS29760 876262b12f81c71580448959192b0631 441 Pfam PF07690 Major Facilitator Superfamily 15 306 1.7E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS29760 876262b12f81c71580448959192b0631 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 253 278 2.5E-5 T 28-03-2018 CNX65_RS29760 876262b12f81c71580448959192b0631 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 102 122 2.5E-5 T 28-03-2018 CNX65_RS29760 876262b12f81c71580448959192b0631 441 PRINTS PR01036 Tetracycline resistance protein TetB signature 132 156 2.5E-5 T 28-03-2018 CNX65_RS03380 3eb2a8ed80df38ea2b1e5ef9b1d0259b 329 Gene3D G3DSA:3.40.50.300 3 329 8.4E-75 T 28-03-2018 CNX65_RS03380 3eb2a8ed80df38ea2b1e5ef9b1d0259b 329 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 1.0E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS03380 3eb2a8ed80df38ea2b1e5ef9b1d0259b 329 SMART SM00382 35 235 8.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03380 3eb2a8ed80df38ea2b1e5ef9b1d0259b 329 Pfam PF00005 ABC transporter 26 185 2.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03380 3eb2a8ed80df38ea2b1e5ef9b1d0259b 329 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03380 3eb2a8ed80df38ea2b1e5ef9b1d0259b 329 SUPERFAMILY SSF52540 6 256 1.15E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03380 3eb2a8ed80df38ea2b1e5ef9b1d0259b 329 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 3.4E-24 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 Gene3D G3DSA:1.10.1740.10 2 75 2.7E-11 T 28-03-2018 CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 SUPERFAMILY SSF88946 3 74 3.41E-12 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 160 9.1E-53 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 Gene3D G3DSA:1.10.10.10 83 165 1.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 Pfam PF04542 Sigma-70 region 2 18 77 2.1E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 SUPERFAMILY SSF88659 98 157 3.74E-16 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 8 155 4.4E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27685 81eae0d6d17629c802c58c4f3bad2422 166 Pfam PF08281 Sigma-70, region 4 101 154 1.2E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Gene3D G3DSA:2.60.260.20 208 256 4.7E-10 T 28-03-2018 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 SUPERFAMILY SSF49493 260 350 6.28E-18 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Gene3D G3DSA:2.10.230.10 143 207 1.9E-15 T 28-03-2018 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Pfam PF00684 DnaJ central domain 145 209 1.5E-11 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Pfam PF00226 DnaJ domain 4 63 4.5E-23 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Pfam PF01556 DnaJ C terminal domain 120 339 1.0E-35 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 SUPERFAMILY SSF46565 3 102 1.23E-31 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Gene3D G3DSA:2.60.260.20 257 366 6.7E-27 T 28-03-2018 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 PRINTS PR00625 DnaJ domain signature 6 24 6.1E-15 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 PRINTS PR00625 DnaJ domain signature 38 58 6.1E-15 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 PRINTS PR00625 DnaJ domain signature 58 77 6.1E-15 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 SUPERFAMILY SSF49493 188 265 4.32E-15 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 SUPERFAMILY SSF49493 113 136 4.32E-15 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 SUPERFAMILY SSF57938 132 212 7.85E-17 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 1 380 36.42 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 Gene3D G3DSA:1.10.287.110 1 108 1.5E-28 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS06190 fabdf48e2a0bd2c60d516d5c0541d251 384 SMART SM00271 3 58 1.9E-28 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS14935 413bdb0017c78292d2406ed49353a81e 384 Pfam PF00155 Aminotransferase class I and II 99 376 1.5E-27 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS14935 413bdb0017c78292d2406ed49353a81e 384 SUPERFAMILY SSF53383 22 381 1.79E-68 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS14935 413bdb0017c78292d2406ed49353a81e 384 Gene3D G3DSA:3.90.1150.10 270 384 8.0E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS14935 413bdb0017c78292d2406ed49353a81e 384 Gene3D G3DSA:3.40.640.10 42 269 9.7E-27 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS15350 6a0718267ea5c356f12f98312a35b8ff 273 SUPERFAMILY SSF49899 8 267 5.09E-36 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS15350 6a0718267ea5c356f12f98312a35b8ff 273 Pfam PF00722 Glycosyl hydrolases family 16 136 228 4.4E-10 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CNX65_RS15350 6a0718267ea5c356f12f98312a35b8ff 273 Gene3D G3DSA:2.60.120.200 11 266 5.6E-34 T 28-03-2018 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 SMART SM00054 41 69 4.2 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 SMART SM00054 164 192 0.0015 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 SMART SM00054 132 160 1.1 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 Gene3D G3DSA:1.10.238.10 57 145 2.6E-9 T 28-03-2018 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 Pfam PF13499 EF-hand domain pair 40 157 1.1E-8 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 SUPERFAMILY SSF47473 40 200 2.4E-20 T 28-03-2018 IPR011992 EF-hand domain pair CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 ProSitePatterns PS00018 EF-hand calcium-binding domain. 173 185 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 ProSitePatterns PS00018 EF-hand calcium-binding domain. 50 62 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 Pfam PF13405 EF-hand domain 167 191 2.4E-6 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 Gene3D G3DSA:1.10.238.10 146 194 9.9E-13 T 28-03-2018 CNX65_RS23020 4f70e9ca1de657f8b06ce31e31c8e20f 209 Gene3D G3DSA:1.10.238.10 21 56 0.027 T 28-03-2018 CNX65_RS29845 00dae621d43dc22898fbd3352849c799 331 Gene3D G3DSA:3.40.50.150 36 311 3.1E-34 T 28-03-2018 CNX65_RS29845 00dae621d43dc22898fbd3352849c799 331 SUPERFAMILY SSF53335 242 270 1.81E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS29845 00dae621d43dc22898fbd3352849c799 331 SUPERFAMILY SSF53335 49 195 1.81E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS29845 00dae621d43dc22898fbd3352849c799 331 Pfam PF08241 Methyltransferase domain 86 183 4.6E-24 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Gene3D G3DSA:1.10.150.80 517 605 1.2E-25 T 28-03-2018 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 SUPERFAMILY SSF47819 532 605 1.18E-21 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Pfam PF00570 HRDC domain 537 603 3.8E-22 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Pfam PF09382 RQC domain 400 513 2.9E-33 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 SMART SM00487 15 211 1.2E-23 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Gene3D G3DSA:1.10.10.10 397 516 1.1E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 SMART SM00490 244 325 8.4E-23 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 SUPERFAMILY SSF52540 201 457 3.59E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Pfam PF00270 DEAD/DEAH box helicase 23 179 2.2E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 9 460 2.6E-150 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Gene3D G3DSA:3.40.50.300 203 396 8.6E-44 T 28-03-2018 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 SMART SM00956 405 511 4.8E-42 T 28-03-2018 IPR018982 RQC domain GO:0006260|GO:0006281|GO:0043140 Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Gene3D G3DSA:3.40.50.300 2 201 3.9E-29 T 28-03-2018 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Pfam PF16124 RecQ zinc-binding 337 398 1.6E-17 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 Pfam PF00271 Helicase conserved C-terminal domain 218 324 2.4E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 SMART SM00341 534 606 1.8E-9 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 TIGRFAM TIGR01389 recQ: ATP-dependent DNA helicase RecQ 8 603 1.3E-231 T 28-03-2018 IPR006293 DNA helicase, ATP-dependent, RecQ type, bacterial GO:0004003|GO:0006310|GO:0009432 CNX65_RS27630 80e17eff7ad1c07982f373ca249a57cf 606 SUPERFAMILY SSF52540 8 190 1.52E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:3.30.559.10 535 733 2.5E-32 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 ProSitePatterns PS00012 Phosphopantetheine attachment site. 473 488 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:3.40.50.1820 1564 1869 3.6E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:1.10.1200.10 296 437 0.075 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Pfam PF00550 Phosphopantetheine attachment site 451 510 4.1E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Pfam PF00550 Phosphopantetheine attachment site 1488 1551 4.2E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Pfam PF00501 AMP-binding enzyme 1001 1382 4.3E-97 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF56801 960 1498 1.57E-148 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:3.40.50.980 990 1141 2.4E-42 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF52777 730 985 2.56E-45 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 ProSitePatterns PS00455 Putative AMP-binding domain signature. 1138 1149 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF52777 185 426 6.78E-54 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Pfam PF00668 Condensation domain 11 425 5.9E-83 T 28-03-2018 IPR001242 Condensation domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Pfam PF00668 Condensation domain 542 979 4.8E-59 T 28-03-2018 IPR001242 Condensation domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1017 1399 2.4E-124 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:1.10.1200.10 1492 1563 4.2E-20 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1510 1525 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Pfam PF13193 AMP-binding enzyme C-terminal domain 1391 1455 4.3E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF53474 1710 1868 3.21E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF47336 1480 1551 4.45E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:3.40.50.980 1142 1292 2.6E-48 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Pfam PF00975 Thioesterase domain 1708 1864 2.9E-10 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF52777 539 741 9.34E-39 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF47336 441 513 5.63E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:2.30.38.10 1301 1376 4.3E-23 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SUPERFAMILY SSF52777 9 196 4.78E-45 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:1.10.1200.10 438 526 2.3E-18 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SMART SM00823 Phosphopantetheine attachment site 1486 1555 6.0E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 SMART SM00823 Phosphopantetheine attachment site 449 517 0.41 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:3.30.300.30 1378 1491 6.4E-28 T 28-03-2018 CNX65_RS22390 3bfec2f4d4cb7f48dccb3f23bc8adeb1 1872 Gene3D G3DSA:3.30.559.10 8 199 1.1E-39 T 28-03-2018 CNX65_RS03055 3846e4615feacdae3a73a4cc5772e862 286 Gene3D G3DSA:1.10.3720.10 2 273 1.9E-37 T 28-03-2018 CNX65_RS03055 3846e4615feacdae3a73a4cc5772e862 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 271 1.7E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03055 3846e4615feacdae3a73a4cc5772e862 286 SUPERFAMILY SSF161098 6 286 4.14E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08645 0972f19be2b3c811edc1d2f658552aae 200 Pfam PF00908 dTDP-4-dehydrorhamnose 3,5-epimerase 18 186 9.0E-68 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CNX65_RS08645 0972f19be2b3c811edc1d2f658552aae 200 TIGRFAM TIGR01221 rmlC: dTDP-4-dehydrorhamnose 3,5-epimerase 15 186 3.8E-67 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CNX65_RS08645 0972f19be2b3c811edc1d2f658552aae 200 SUPERFAMILY SSF51182 13 191 1.19E-70 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS08645 0972f19be2b3c811edc1d2f658552aae 200 Gene3D G3DSA:2.60.120.10 4 195 1.5E-70 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS08645 0972f19be2b3c811edc1d2f658552aae 200 ProDom PD001462 35-EPIMERASE DTDP-4-DEHYDRORHAMNOSE ISOMERASE RMLC EPIMERASE RELATED DTDP-6-DEOXY-D-GLUCOSE-35-EPIMERASE DTDP-4-KETO-6-DEOXY-D-GLUCOSE DTDP-4-KETO-6-DEOXYGLUCOSE-35-EPIMERASE DTDP-L-RHAMNOSE 19 185 5.0E-52 T 28-03-2018 IPR000888 dTDP-4-dehydrorhamnose 3,5-epimerase-related GO:0008830 CNX65_RS34875 dcbedd06cdcbdc5e075b21ee219dd88a 41 Pfam PF04149 Domain of unknown function (DUF397) 3 33 3.2E-8 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS23480 77fad6a63605d579b317fb11ba5d067c 321 SUPERFAMILY SSF161098 93 304 5.49E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS23480 77fad6a63605d579b317fb11ba5d067c 321 Gene3D G3DSA:1.10.3720.10 1 317 4.9E-36 T 28-03-2018 CNX65_RS23480 77fad6a63605d579b317fb11ba5d067c 321 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 316 8.8E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 56 75 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 215 225 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 262 282 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 99 112 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 247 260 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 127 142 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 286 300 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PRINTS PR00733 Glycosyl hydrolase family 6 signature 184 197 1.1E-42 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 Pfam PF01341 Glycosyl hydrolases family 6 52 302 3.0E-63 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 Gene3D G3DSA:3.20.20.40 34 320 1.8E-87 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 SUPERFAMILY SSF49384 338 440 7.67E-25 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 Pfam PF00553 Cellulose binding domain 342 440 1.5E-22 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 SMART SM00637 342 440 1.3E-28 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 SUPERFAMILY SSF51989 37 319 1.44E-84 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PIRSF PIRSF001100 322 441 4000.0 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 PIRSF PIRSF001100 2 324 4.3E-81 T 28-03-2018 IPR016288 1, 4-beta cellobiohydrolase GO:0004553|GO:0030245 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 ProSitePatterns PS00655 Glycosyl hydrolases family 6 signature 1. 104 120 - T 28-03-2018 IPR001524 Glycoside hydrolase, family 6, conserved site GO:0004553|GO:0005975 CNX65_RS16385 0f723fcca0ed4f27c6690993edbbb2f7 441 Gene3D G3DSA:2.60.40.290 330 440 1.8E-28 T 28-03-2018 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 SMART SM00422 1 69 2.6E-19 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 Pfam PF13411 MerR HTH family regulatory protein 2 67 9.1E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 Gene3D G3DSA:1.10.1660.10 55 124 1.5E-7 T 28-03-2018 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 6.5E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 6.5E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 6.5E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 SUPERFAMILY SSF46955 2 116 1.25E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 ProSitePatterns PS00552 MerR-type HTH domain signature. 4 26 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS11105 4b3446d15a4894431a08fcbb678a3ba4 125 Gene3D G3DSA:1.10.1660.10 1 54 5.0E-19 T 28-03-2018 CNX65_RS14520 199ae7f884cbe4156deaaa1647aeef49 198 SUPERFAMILY SSF51366 1 195 8.16E-51 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS14520 199ae7f884cbe4156deaaa1647aeef49 198 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 192 2.5E-43 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CNX65_RS14520 199ae7f884cbe4156deaaa1647aeef49 198 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 198 33.891 T 28-03-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 CNX65_RS14520 199ae7f884cbe4156deaaa1647aeef49 198 Gene3D G3DSA:3.20.20.70 1 197 6.6E-58 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 SUPERFAMILY SSF53187 318 410 2.64E-69 T 28-03-2018 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 SUPERFAMILY SSF53187 20 217 2.64E-69 T 28-03-2018 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 Pfam PF01546 Peptidase family M20/M25/M40 89 406 4.3E-25 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 Gene3D G3DSA:3.40.630.10 10 291 8.8E-57 T 28-03-2018 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 32 397 7.4E-98 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 Gene3D G3DSA:3.40.630.10 292 411 9.6E-4 T 28-03-2018 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 PIRSF PIRSF005962 18 411 1.4E-107 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 Pfam PF07687 Peptidase dimerisation domain 205 302 4.7E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS00860 6f8aeed02b8a3cbd5100ff34de151872 411 SUPERFAMILY SSF55031 203 316 3.14E-31 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS16125 fd7e853f4b7d21a9dec27cce0c19278a 429 Gene3D G3DSA:1.20.91.10 262 346 5.6E-17 T 28-03-2018 CNX65_RS16125 fd7e853f4b7d21a9dec27cce0c19278a 429 Pfam PF00999 Sodium/hydrogen exchanger family 32 415 3.6E-52 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CNX65_RS17070 7e11e0671e5d9570843fa6b4b74e4444 139 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 81 3.2E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS17070 7e11e0671e5d9570843fa6b4b74e4444 139 SUPERFAMILY SSF46785 11 83 2.41E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17070 7e11e0671e5d9570843fa6b4b74e4444 139 Gene3D G3DSA:1.10.10.10 5 82 3.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17070 7e11e0671e5d9570843fa6b4b74e4444 139 SMART SM00345 22 81 5.2E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS26740 408be84351b22bf8f07ffbb155537382 181 Gene3D G3DSA:1.10.1740.10 5 85 2.9E-22 T 28-03-2018 CNX65_RS26740 408be84351b22bf8f07ffbb155537382 181 Pfam PF04545 Sigma-70, region 4 120 169 6.8E-13 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26740 408be84351b22bf8f07ffbb155537382 181 Pfam PF04542 Sigma-70 region 2 21 88 8.9E-20 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26740 408be84351b22bf8f07ffbb155537382 181 Gene3D G3DSA:1.10.10.10 86 174 2.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26740 408be84351b22bf8f07ffbb155537382 181 SUPERFAMILY SSF88946 12 95 3.88E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26740 408be84351b22bf8f07ffbb155537382 181 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 18 169 1.1E-26 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26740 408be84351b22bf8f07ffbb155537382 181 SUPERFAMILY SSF88659 107 171 3.74E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 Pfam PF01926 50S ribosome-binding GTPase 161 288 2.5E-22 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 Gene3D G3DSA:2.70.210.12 3 156 5.2E-52 T 28-03-2018 IPR006169 GTP1/OBG domain CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 8.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 183 201 8.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 8.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 162 182 8.1E-35 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 Hamap MF_01454 GTPase Obg [obg]. 3 335 44.303 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 Pfam PF01018 GTP1/OBG 5 157 4.5E-51 T 28-03-2018 IPR006169 GTP1/OBG domain CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 28-03-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 4 334 3.7E-125 T 28-03-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 367 432 1.1E-24 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 Pfam PF09269 Domain of unknown function (DUF1967) 361 431 1.1E-23 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 Gene3D G3DSA:3.40.50.300 159 345 1.5E-31 T 28-03-2018 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 SUPERFAMILY SSF102741 361 433 1.05E-19 T 28-03-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 SUPERFAMILY SSF82051 4 157 4.32E-47 T 28-03-2018 IPR006169 GTP1/OBG domain CNX65_RS05925 0b0e023fdb6cbef92945e4ed5617866e 488 SUPERFAMILY SSF52540 151 344 1.59E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28065 27c01c7e37fb24ad82e1885b8f71d465 259 SUPERFAMILY SSF56317 1 257 1.57E-64 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS28065 27c01c7e37fb24ad82e1885b8f71d465 259 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 138 158 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CNX65_RS28065 27c01c7e37fb24ad82e1885b8f71d465 259 Gene3D G3DSA:3.60.110.10 1 259 2.6E-65 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS28065 27c01c7e37fb24ad82e1885b8f71d465 259 Pfam PF00795 Carbon-nitrogen hydrolase 2 248 2.8E-37 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS19190 573721e0b1c7b3d50cc02801cfff9538 307 Gene3D G3DSA:3.40.50.720 135 241 1.1E-20 T 28-03-2018 CNX65_RS19190 573721e0b1c7b3d50cc02801cfff9538 307 SUPERFAMILY SSF50129 7 130 1.42E-20 T 28-03-2018 IPR011032 GroES-like CNX65_RS19190 573721e0b1c7b3d50cc02801cfff9538 307 Pfam PF13602 Zinc-binding dehydrogenase 177 304 1.6E-9 T 28-03-2018 CNX65_RS19190 573721e0b1c7b3d50cc02801cfff9538 307 SMART SM00829 9 304 2.1E-7 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS19190 573721e0b1c7b3d50cc02801cfff9538 307 Gene3D G3DSA:3.90.180.10 1 134 2.4E-27 T 28-03-2018 CNX65_RS19190 573721e0b1c7b3d50cc02801cfff9538 307 SUPERFAMILY SSF51735 110 231 1.14E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 Pfam PF13620 Carboxypeptidase regulatory-like domain 57 111 8.2E-12 T 28-03-2018 CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 SMART SM00458 256 393 1.2E-12 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 Gene3D G3DSA:2.80.10.50 255 356 1.2E-15 T 28-03-2018 CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 SUPERFAMILY SSF49478 35 105 1.92E-11 T 28-03-2018 CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 Pfam PF17210 SdrD B-like domain 131 246 1.5E-12 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 SUPERFAMILY SSF117074 127 206 3.53E-10 T 28-03-2018 CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 Gene3D G3DSA:2.80.10.50 357 393 3.1E-6 T 28-03-2018 CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 SUPERFAMILY SSF50370 259 390 5.2E-21 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 Gene3D G3DSA:2.60.40.10 127 254 8.9E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 Gene3D G3DSA:2.60.40.1120 27 121 1.4E-14 T 28-03-2018 CNX65_RS12960 0d80e0b8e7d27b1c30dcac1a812a6958 393 Pfam PF00652 Ricin-type beta-trefoil lectin domain 259 348 5.2E-10 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS16535 c553fa684c6ab545d9d666ff1393e032 342 PIRSF PIRSF001455 18 340 3.1E-75 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS16535 c553fa684c6ab545d9d666ff1393e032 342 Gene3D G3DSA:3.40.50.1970 7 169 3.7E-38 T 28-03-2018 CNX65_RS16535 c553fa684c6ab545d9d666ff1393e032 342 SUPERFAMILY SSF56796 11 336 5.5E-87 T 28-03-2018 CNX65_RS16535 c553fa684c6ab545d9d666ff1393e032 342 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 8 338 30.417 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS16535 c553fa684c6ab545d9d666ff1393e032 342 Pfam PF01761 3-dehydroquinate synthase 66 307 4.0E-77 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS16535 c553fa684c6ab545d9d666ff1393e032 342 Gene3D G3DSA:1.20.1090.10 170 342 8.4E-41 T 28-03-2018 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 SUPERFAMILY SSF53223 3 122 3.17E-34 T 28-03-2018 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 Gene3D G3DSA:3.40.50.10860 11 139 4.2E-40 T 28-03-2018 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 SUPERFAMILY SSF51735 135 278 3.85E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 279 34.087 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 155 175 2.1E-48 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 34 56 2.1E-48 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 110 131 2.1E-48 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 235 251 2.1E-48 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 75 102 2.1E-48 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 252 270 2.1E-48 T 28-03-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 128 278 7.8E-57 T 28-03-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 Gene3D G3DSA:3.40.50.720 140 260 8.2E-32 T 28-03-2018 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 256 264 - T 28-03-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS20100 d81b4a9fed6a2e1c0f03eb95cc44c4ec 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 6 121 1.2E-35 T 28-03-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|Reactome: R-HSA-196757 CNX65_RS13980 2a6e64007824da88c6bc02eafb0eac56 388 SMART SM00387 299 388 9.0E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13980 2a6e64007824da88c6bc02eafb0eac56 388 Pfam PF07730 Histidine kinase 199 265 2.0E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS13980 2a6e64007824da88c6bc02eafb0eac56 388 SUPERFAMILY SSF55874 280 385 7.38E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13980 2a6e64007824da88c6bc02eafb0eac56 388 Gene3D G3DSA:3.30.565.10 270 388 3.4E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31335 4f021b6d20460c832ffae487239d3bf4 221 SMART SM00448 1 111 1.7E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS31335 4f021b6d20460c832ffae487239d3bf4 221 Pfam PF00072 Response regulator receiver domain 2 112 3.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS31335 4f021b6d20460c832ffae487239d3bf4 221 Gene3D G3DSA:1.10.10.10 124 221 7.6E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31335 4f021b6d20460c832ffae487239d3bf4 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 141 217 2.0E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS31335 4f021b6d20460c832ffae487239d3bf4 221 SMART SM00862 141 217 2.6E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS31335 4f021b6d20460c832ffae487239d3bf4 221 Gene3D G3DSA:3.40.50.2300 1 123 1.1E-38 T 28-03-2018 CNX65_RS31335 4f021b6d20460c832ffae487239d3bf4 221 SUPERFAMILY SSF52172 2 176 1.17E-41 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS01070 3e8db2579670918bb49c555354cdbc9a 272 Pfam PF08241 Methyltransferase domain 80 172 7.0E-18 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS01070 3e8db2579670918bb49c555354cdbc9a 272 Gene3D G3DSA:3.40.50.150 48 267 6.2E-26 T 28-03-2018 CNX65_RS01070 3e8db2579670918bb49c555354cdbc9a 272 SUPERFAMILY SSF53335 52 267 1.09E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS33100 a57f8d4f5992d8ae5a5b48b440909147 195 Pfam PF00578 AhpC/TSA family 66 174 3.0E-21 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS33100 a57f8d4f5992d8ae5a5b48b440909147 195 SUPERFAMILY SSF52833 57 194 2.2E-31 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS33100 a57f8d4f5992d8ae5a5b48b440909147 195 Gene3D G3DSA:3.40.30.10 36 185 1.7E-29 T 28-03-2018 CNX65_RS33100 a57f8d4f5992d8ae5a5b48b440909147 195 ProSitePatterns PS00194 Thioredoxin family active site. 82 100 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CNX65_RS24810 84b0145dc867951907c9448714cfeeb0 260 Gene3D G3DSA:3.40.1130.10 17 238 1.1E-44 T 28-03-2018 CNX65_RS24810 84b0145dc867951907c9448714cfeeb0 260 SMART SM00563 48 166 1.1E-30 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS24810 84b0145dc867951907c9448714cfeeb0 260 SUPERFAMILY SSF69593 16 227 3.4E-38 T 28-03-2018 CNX65_RS24810 84b0145dc867951907c9448714cfeeb0 260 Pfam PF01553 Acyltransferase 34 162 1.0E-24 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS26570 3c8518b4d20309800654313eecc7b839 345 Pfam PF00182 Chitinase class I 144 345 1.6E-41 T 28-03-2018 IPR000726 Glycoside hydrolase, family 19, catalytic GO:0004568|GO:0006032|GO:0016998 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS26570 3c8518b4d20309800654313eecc7b839 345 Gene3D G3DSA:1.10.530.10 140 345 8.6E-63 T 28-03-2018 CNX65_RS26570 3c8518b4d20309800654313eecc7b839 345 Gene3D G3DSA:2.10.10.20 79 128 1.7E-7 T 28-03-2018 CNX65_RS26570 3c8518b4d20309800654313eecc7b839 345 Gene3D G3DSA:2.10.10.20 19 68 4.7E-4 T 28-03-2018 CNX65_RS26570 3c8518b4d20309800654313eecc7b839 345 SUPERFAMILY SSF53955 141 345 2.39E-65 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS26570 3c8518b4d20309800654313eecc7b839 345 PIRSF PIRSF001060 48 345 4.5E-81 T 28-03-2018 IPR016283 Glycoside hydrolase, family 19 GO:0004568|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 SUPERFAMILY SSF50129 1 140 2.28E-40 T 28-03-2018 IPR011032 GroES-like CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 TIGRFAM TIGR02824 quinone_pig3: putative NAD(P)H quinone oxidoreductase, PIG3 family 1 322 2.3E-129 T 28-03-2018 IPR014189 Quinone oxidoreductase PIG3 Reactome: R-HSA-6803205 CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 SMART SM00829 10 321 1.7E-33 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 87 3.3E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 Gene3D G3DSA:3.40.50.720 135 306 2.2E-36 T 28-03-2018 CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 SUPERFAMILY SSF51735 111 264 4.48E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 Gene3D G3DSA:3.90.180.10 1 134 4.3E-42 T 28-03-2018 CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 Pfam PF13602 Zinc-binding dehydrogenase 183 321 7.0E-22 T 28-03-2018 CNX65_RS00700 03b3c2437cffb9ee4e33cba0884a6892 324 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 140 161 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS07460 a5880174bffd801badf5b1a6ad5cf1f7 390 Gene3D G3DSA:1.10.10.10 11 78 9.2E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07460 a5880174bffd801badf5b1a6ad5cf1f7 390 Gene3D G3DSA:3.30.420.40 79 203 4.4E-25 T 28-03-2018 CNX65_RS07460 a5880174bffd801badf5b1a6ad5cf1f7 390 SUPERFAMILY SSF46785 13 77 1.5E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07460 a5880174bffd801badf5b1a6ad5cf1f7 390 Pfam PF00480 ROK family 88 382 4.6E-50 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS07460 a5880174bffd801badf5b1a6ad5cf1f7 390 Gene3D G3DSA:3.30.420.40 204 388 1.6E-48 T 28-03-2018 CNX65_RS07460 a5880174bffd801badf5b1a6ad5cf1f7 390 SUPERFAMILY SSF53067 87 384 6.48E-43 T 28-03-2018 CNX65_RS21995 b7588743a491106319b907bdc9f216ff 180 SUPERFAMILY SSF55797 54 178 2.09E-24 T 28-03-2018 IPR014044 CAP domain CNX65_RS21995 b7588743a491106319b907bdc9f216ff 180 Gene3D G3DSA:3.40.33.10 48 179 1.0E-17 T 28-03-2018 IPR014044 CAP domain CNX65_RS21995 b7588743a491106319b907bdc9f216ff 180 Pfam PF00188 Cysteine-rich secretory protein family 61 177 8.5E-19 T 28-03-2018 IPR014044 CAP domain CNX65_RS09325 271394a54eb1f812aa9a7a9c1befd628 405 Pfam PF13529 Peptidase_C39 like family 209 360 4.0E-33 T 28-03-2018 CNX65_RS09325 271394a54eb1f812aa9a7a9c1befd628 405 Gene3D G3DSA:3.90.70.10 230 405 2.7E-18 T 28-03-2018 CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 Pfam PF16542 PNKP adenylyltransferase domain, ligase domain 464 771 5.3E-138 T 28-03-2018 IPR032380 Polynucleotide kinase-phosphatase, ligase domain CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 Gene3D G3DSA:3.40.50.300 1 19 0.0014 T 28-03-2018 CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 Pfam PF13671 AAA domain 10 135 2.4E-22 T 28-03-2018 CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 Gene3D G3DSA:3.60.21.10 176 425 3.7E-53 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 SUPERFAMILY SSF56300 175 414 1.52E-42 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 TIGRFAM TIGR04075 bacter_Pnkp: polynucleotide kinase-phosphatase 1 834 0.0 T 28-03-2018 IPR024028 Polynucleotide kinase-phosphatase, bacterial CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 SUPERFAMILY SSF52540 3 130 2.0E-16 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 Pfam PF16536 PNKP adenylyltransferase domain, C-terminal region 775 834 2.4E-31 T 28-03-2018 IPR032390 Polynucleotide kinase-phosphatase, C-terminal CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 Gene3D G3DSA:3.40.50.300 20 175 3.2E-17 T 28-03-2018 CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 SUPERFAMILY SSF56091 510 599 2.59E-13 T 28-03-2018 CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 SUPERFAMILY SSF56091 626 748 2.59E-13 T 28-03-2018 CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 Pfam PF00149 Calcineurin-like phosphoesterase 181 387 1.6E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS17755 c4030dc83bc2c5af14aa2a5ed82efd2b 834 SMART SM00382 7 181 0.0013 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS00330 7c8f6ebd9bb57a704d60cc41802bd762 488 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 188 5.2E-16 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS00330 7c8f6ebd9bb57a704d60cc41802bd762 488 Pfam PF04542 Sigma-70 region 2 40 99 3.1E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS00330 7c8f6ebd9bb57a704d60cc41802bd762 488 SUPERFAMILY SSF88659 129 188 6.17E-7 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS00330 7c8f6ebd9bb57a704d60cc41802bd762 488 Gene3D G3DSA:1.10.10.10 134 260 9.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00330 7c8f6ebd9bb57a704d60cc41802bd762 488 Gene3D G3DSA:1.10.1740.10 21 103 1.5E-19 T 28-03-2018 CNX65_RS00330 7c8f6ebd9bb57a704d60cc41802bd762 488 Pfam PF13490 Putative zinc-finger 204 237 2.5E-5 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS00330 7c8f6ebd9bb57a704d60cc41802bd762 488 SUPERFAMILY SSF88946 22 114 2.67E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14400 1b790952704e3d72ff8de50e4ceb3e0f 405 Gene3D G3DSA:3.40.190.10 79 223 2.5E-17 T 28-03-2018 CNX65_RS14400 1b790952704e3d72ff8de50e4ceb3e0f 405 Pfam PF13416 Bacterial extracellular solute-binding protein 100 369 1.1E-25 T 28-03-2018 CNX65_RS14400 1b790952704e3d72ff8de50e4ceb3e0f 405 Gene3D G3DSA:3.40.190.10 224 376 2.7E-4 T 28-03-2018 CNX65_RS14400 1b790952704e3d72ff8de50e4ceb3e0f 405 SUPERFAMILY SSF53850 81 399 3.31E-38 T 28-03-2018 CNX65_RS14400 1b790952704e3d72ff8de50e4ceb3e0f 405 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 45 71 5.1E-4 T 28-03-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 82 1.4E-7 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 SUPERFAMILY SSF51735 110 280 4.76E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 Pfam PF00107 Zinc-binding dehydrogenase 146 258 2.6E-24 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 SUPERFAMILY SSF50129 1 144 5.48E-36 T 28-03-2018 IPR011032 GroES-like CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 135 156 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 SMART SM00829 10 313 1.8E-32 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 Gene3D G3DSA:3.40.50.720 130 283 7.4E-27 T 28-03-2018 CNX65_RS17690 989fd8548522c2d431d77cdcef0bd892 315 Gene3D G3DSA:3.90.180.10 1 129 1.5E-36 T 28-03-2018 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 SMART SM00642 162 568 5.0E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 14 100 9.7E-20 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 SUPERFAMILY SSF51445 148 471 2.46E-127 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 SUPERFAMILY SSF51445 500 575 2.46E-127 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 Gene3D G3DSA:3.20.20.80 146 580 5.8E-109 T 28-03-2018 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 Gene3D G3DSA:2.60.40.1180 581 700 3.9E-26 T 28-03-2018 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 10 697 4.2E-261 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 Pfam PF00128 Alpha amylase, catalytic domain 195 276 3.6E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 SUPERFAMILY SSF51011 586 697 3.52E-18 T 28-03-2018 CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 SUPERFAMILY SSF81296 10 122 1.34E-36 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS29860 6dae5ebce3b9bb2650aa65d97631d429 700 Gene3D G3DSA:2.60.40.10 9 141 3.1E-42 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 Pfam PF11975 Family 4 glycosyl hydrolase C-terminal domain 178 383 8.3E-38 T 28-03-2018 IPR022616 Glycosyl hydrolase, family 4, C-terminal GO:0004553 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 SUPERFAMILY SSF51735 1 163 1.41E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 Gene3D G3DSA:3.90.110.10 153 405 1.0E-74 T 28-03-2018 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 PRINTS PR00732 Glycosyl hydrolase family 4 signature 2 17 2.0E-25 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 PRINTS PR00732 Glycosyl hydrolase family 4 signature 82 95 2.0E-25 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 PRINTS PR00732 Glycosyl hydrolase family 4 signature 150 161 2.0E-25 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 PRINTS PR00732 Glycosyl hydrolase family 4 signature 125 142 2.0E-25 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 PRINTS PR00732 Glycosyl hydrolase family 4 signature 96 116 2.0E-25 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 SUPERFAMILY SSF56327 154 402 2.09E-52 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 Gene3D G3DSA:3.40.50.720 1 152 8.4E-32 T 28-03-2018 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 Pfam PF02056 Family 4 glycosyl hydrolase 26 170 8.1E-38 T 28-03-2018 IPR001088 Glycoside hydrolase, family 4 GO:0004553|GO:0005975 CNX65_RS07225 ee67dd070feed924bdf26ce08d52e364 407 ProSitePatterns PS01324 Glycosyl hydrolases family 4 signature. 125 155 - T 28-03-2018 IPR019802 Glycoside hydrolase, family 4, conserved site GO:0004553|GO:0005975 CNX65_RS10760 fca4d681824750895f1aea8e4268a148 160 TIGRFAM TIGR03086 TIGR03086: TIGR03086 family protein 3 158 1.4E-39 T 28-03-2018 IPR017520 Conserved hypothetical protein CHP03086 CNX65_RS10760 fca4d681824750895f1aea8e4268a148 160 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 3 158 3.3E-16 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS10760 fca4d681824750895f1aea8e4268a148 160 SUPERFAMILY SSF109854 3 108 5.49E-13 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS10760 fca4d681824750895f1aea8e4268a148 160 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 3 102 4.7E-10 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS10760 fca4d681824750895f1aea8e4268a148 160 Gene3D G3DSA:1.20.120.450 1 108 1.4E-10 T 28-03-2018 CNX65_RS02990 9527e6925181360428872a14189d050f 615 Gene3D G3DSA:3.30.70.270 330 490 1.1E-45 T 28-03-2018 CNX65_RS02990 9527e6925181360428872a14189d050f 615 SUPERFAMILY SSF55073 326 483 4.55E-37 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS02990 9527e6925181360428872a14189d050f 615 SMART SM00267 311 484 1.2E-42 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS02990 9527e6925181360428872a14189d050f 615 Gene3D G3DSA:1.25.40.10 153 329 0.0033 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS02990 9527e6925181360428872a14189d050f 615 Pfam PF00990 Diguanylate cyclase, GGDEF domain 321 480 1.8E-33 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS02990 9527e6925181360428872a14189d050f 615 SUPERFAMILY SSF48452 17 184 7.6E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS02990 9527e6925181360428872a14189d050f 615 Gene3D G3DSA:1.25.40.10 12 142 9.7E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS02990 9527e6925181360428872a14189d050f 615 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 319 483 7.6E-38 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 Pfam PF00813 FliP family 97 288 1.1E-75 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 214 226 1.2E-14 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 152 164 1.2E-14 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 282 292 1.2E-14 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 164 178 1.2E-14 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 92 101 1.2E-14 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 192 204 1.2E-14 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 97 291 2.9E-75 T 28-03-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 269 281 - T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 242 263 2.8E-60 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 113 133 2.8E-60 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 266 291 2.8E-60 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 133 152 2.8E-60 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 94 113 2.8E-60 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS11870 486a2c0e7d835e5de22f94dfe7ed6da8 293 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 221 241 2.8E-60 T 28-03-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 CNX65_RS25725 3e9c4578c20e34e75e5521234eea9afd 993 SMART SM00387 524 640 1.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25725 3e9c4578c20e34e75e5521234eea9afd 993 Pfam PF08376 Nitrate and nitrite sensing 72 307 6.0E-34 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CNX65_RS25725 3e9c4578c20e34e75e5521234eea9afd 993 SUPERFAMILY SSF55874 512 638 3.14E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25725 3e9c4578c20e34e75e5521234eea9afd 993 Gene3D G3DSA:3.30.565.10 401 638 3.2E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25725 3e9c4578c20e34e75e5521234eea9afd 993 Pfam PF00672 HAMP domain 346 408 1.0E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS28470 4f7b6a2dd88fc2c4617d401ca3ae69da 487 Gene3D G3DSA:1.10.510.10 108 375 4.0E-47 T 28-03-2018 CNX65_RS28470 4f7b6a2dd88fc2c4617d401ca3ae69da 487 SMART SM00220 20 274 3.9E-58 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS28470 4f7b6a2dd88fc2c4617d401ca3ae69da 487 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 26 49 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS28470 4f7b6a2dd88fc2c4617d401ca3ae69da 487 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS28470 4f7b6a2dd88fc2c4617d401ca3ae69da 487 Pfam PF00069 Protein kinase domain 20 270 4.3E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS28470 4f7b6a2dd88fc2c4617d401ca3ae69da 487 Gene3D G3DSA:3.30.200.20 2 107 2.8E-21 T 28-03-2018 CNX65_RS28470 4f7b6a2dd88fc2c4617d401ca3ae69da 487 SUPERFAMILY SSF56112 8 301 2.56E-68 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 SUPERFAMILY SSF51735 17 260 7.46E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 26 260 6.4E-54 T 28-03-2018 CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 6.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 244 6.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 6.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 6.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 6.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 159 6.1E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 157 185 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 157 2.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 92 103 2.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 2.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 Gene3D G3DSA:3.40.50.720 56 266 2.2E-58 T 28-03-2018 CNX65_RS17545 c6f84191ff470784c934535ae9d901d4 267 Gene3D G3DSA:3.40.50.720 10 55 4.2E-9 T 28-03-2018 CNX65_RS17330 be956277663ef0b02cf251135b596ade 272 Gene3D G3DSA:2.40.290.10 1 175 2.9E-22 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CNX65_RS17330 be956277663ef0b02cf251135b596ade 272 SUPERFAMILY SSF100939 1 229 2.55E-37 T 28-03-2018 IPR016194 SPOC-like, C-terminal domain CNX65_RS17330 be956277663ef0b02cf251135b596ade 272 SMART SM00559 52 179 1.7E-22 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CNX65_RS17330 be956277663ef0b02cf251135b596ade 272 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 1 265 28.437 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CNX65_RS17330 be956277663ef0b02cf251135b596ade 272 PIRSF PIRSF006493 1 272 2.7E-61 T 28-03-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type CNX65_RS17330 be956277663ef0b02cf251135b596ade 272 Pfam PF02735 Ku70/Ku80 beta-barrel domain 12 174 3.0E-24 T 28-03-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 CNX65_RS20175 c10e49dd9f1e9204f6a36480092a1bd1 298 Pfam PF03984 Repeat of unknown function (DUF346) 148 183 4.0E-6 T 28-03-2018 IPR007132 Protein of unknown function DUF346 CNX65_RS20175 c10e49dd9f1e9204f6a36480092a1bd1 298 Pfam PF03984 Repeat of unknown function (DUF346) 238 273 2.5E-7 T 28-03-2018 IPR007132 Protein of unknown function DUF346 CNX65_RS20175 c10e49dd9f1e9204f6a36480092a1bd1 298 Pfam PF03984 Repeat of unknown function (DUF346) 104 137 1.5E-6 T 28-03-2018 IPR007132 Protein of unknown function DUF346 CNX65_RS20175 c10e49dd9f1e9204f6a36480092a1bd1 298 Gene3D G3DSA:2.120.10.70 181 298 2.5E-35 T 28-03-2018 CNX65_RS20175 c10e49dd9f1e9204f6a36480092a1bd1 298 Gene3D G3DSA:2.120.10.70 7 180 6.4E-37 T 28-03-2018 CNX65_RS20175 c10e49dd9f1e9204f6a36480092a1bd1 298 SUPERFAMILY SSF89372 41 297 1.83E-58 T 28-03-2018 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 SUPERFAMILY SSF53244 316 462 1.53E-45 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 Gene3D G3DSA:3.40.1190.10 96 317 6.5E-43 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 8 456 5.7E-145 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 SUPERFAMILY SSF53623 95 315 5.84E-53 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 Pfam PF08245 Mur ligase middle domain 114 297 6.4E-28 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 402 2.0E-24 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 Gene3D G3DSA:3.90.190.20 318 464 1.0E-40 T 28-03-2018 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 Gene3D G3DSA:3.40.50.720 3 95 3.2E-16 T 28-03-2018 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 5 464 38.022 T 28-03-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 Pfam PF01225 Mur ligase family, catalytic domain 8 110 1.3E-26 T 28-03-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 CNX65_RS28240 74e153a2da480912be199c666cee1354 466 SUPERFAMILY SSF51984 7 95 1.31E-23 T 28-03-2018 CNX65_RS31365 e2f19f16a2fa4170f3d96a78aec3000a 309 Gene3D G3DSA:3.20.20.70 16 309 2.1E-103 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS31365 e2f19f16a2fa4170f3d96a78aec3000a 309 Pfam PF00682 HMGL-like 21 289 4.6E-45 T 28-03-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 CNX65_RS31365 e2f19f16a2fa4170f3d96a78aec3000a 309 SUPERFAMILY SSF51569 18 305 2.49E-68 T 28-03-2018 CNX65_RS05415 225925b24dfce266a04707747e67d416 830 Gene3D G3DSA:1.25.40.10 84 459 3.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05415 225925b24dfce266a04707747e67d416 830 SUPERFAMILY SSF52540 23 62 7.45E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05415 225925b24dfce266a04707747e67d416 830 Gene3D G3DSA:1.20.1250.10 462 651 5.3E-5 T 28-03-2018 CNX65_RS05415 225925b24dfce266a04707747e67d416 830 Gene3D G3DSA:3.40.50.300 17 83 4.3E-4 T 28-03-2018 CNX65_RS16945 59877cc6b485ad92e3f5862e235ebf19 336 Pfam PF00248 Aldo/keto reductase family 15 310 2.6E-58 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS16945 59877cc6b485ad92e3f5862e235ebf19 336 Gene3D G3DSA:3.20.20.100 1 314 5.7E-78 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS16945 59877cc6b485ad92e3f5862e235ebf19 336 SUPERFAMILY SSF51430 1 311 2.36E-80 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 SUPERFAMILY SSF52540 1 179 1.22E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 28-03-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 PRINTS PR00094 Adenylate kinase signature 129 144 7.6E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 PRINTS PR00094 Adenylate kinase signature 146 160 7.6E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 PRINTS PR00094 Adenylate kinase signature 4 17 7.6E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 PRINTS PR00094 Adenylate kinase signature 32 46 7.6E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 PRINTS PR00094 Adenylate kinase signature 81 97 7.6E-30 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 Hamap MF_00235 Adenylate kinase [adk]. 1 180 43.56 T 28-03-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 Pfam PF00406 Adenylate kinase 5 156 2.5E-53 T 28-03-2018 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 Gene3D G3DSA:3.40.50.300 1 128 7.9E-39 T 28-03-2018 CNX65_RS32345 eeb634b23d9466ccb07ba411d9b8b594 183 Gene3D G3DSA:3.40.50.300 129 183 9.2E-6 T 28-03-2018 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 Pfam PF00557 Metallopeptidase family M24 148 352 4.6E-63 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 PRINTS PR00599 Methionine aminopeptidase-1 signature 320 332 2.1E-8 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 PRINTS PR00599 Methionine aminopeptidase-1 signature 200 213 2.1E-8 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 PRINTS PR00599 Methionine aminopeptidase-1 signature 222 238 2.1E-8 T 28-03-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 Pfam PF01321 Creatinase/Prolidase N-terminal domain 6 140 3.6E-23 T 28-03-2018 IPR000587 Creatinase, N-terminal GO:0016787 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 SUPERFAMILY SSF53092 5 139 1.17E-22 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 Gene3D G3DSA:3.90.230.10 125 368 7.9E-79 T 28-03-2018 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 SUPERFAMILY SSF55920 139 368 1.57E-74 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 Gene3D G3DSA:3.40.350.10 2 124 2.8E-26 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CNX65_RS26130 fd91d1adb251373a03a57f12635d6065 368 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 298 310 - T 28-03-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 Pfam PF00089 Trypsin 162 294 1.4E-8 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 Gene3D G3DSA:2.40.10.10 283 370 1.8E-16 T 28-03-2018 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 Gene3D G3DSA:2.40.10.10 188 262 1.6E-6 T 28-03-2018 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 Gene3D G3DSA:2.40.10.10 159 187 4.4E-5 T 28-03-2018 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 ProSitePatterns PS00673 Serine proteases, V8 family, serine active site. 314 324 - T 28-03-2018 IPR000126 Serine proteases, V8 family, serine active site GO:0006508|GO:0008236 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 PRINTS PR00839 V8 serine protease family signature 182 199 2.4E-16 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 PRINTS PR00839 V8 serine protease family signature 308 324 2.4E-16 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 PRINTS PR00839 V8 serine protease family signature 158 175 2.4E-16 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 PRINTS PR00839 V8 serine protease family signature 275 288 2.4E-16 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 PRINTS PR00839 V8 serine protease family signature 211 223 2.4E-16 T 28-03-2018 IPR008256 Peptidase S1B GO:0006508|GO:0008236 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 193 198 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS22490 efa5fb5f82b54e89972f9e0cee9ab43d 374 SUPERFAMILY SSF50494 149 357 4.66E-26 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 Gene3D G3DSA:1.20.120.640 330 412 7.3E-12 T 28-03-2018 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 SUPERFAMILY SSF52374 27 335 3.49E-67 T 28-03-2018 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 TIGRFAM TIGR03447 mycothiol_MshC: cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase 2 412 1.0E-208 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 38 335 1.6E-80 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 244 265 2.1E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 40 51 2.1E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 76 85 2.1E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 213 231 2.1E-23 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 Gene3D G3DSA:3.40.50.620 1 329 1.1E-70 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS11210 902db69d33f31ddc2dfde41ae27f74da 412 Hamap MF_01697 L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase [mshC]. 9 412 53.212 T 28-03-2018 IPR017812 Mycothiol ligase MshC GO:0010125|GO:0035446 CNX65_RS29650 b35dcc3170893e8af10c4c3529b9d459 322 SUPERFAMILY SSF53474 23 292 3.21E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29650 b35dcc3170893e8af10c4c3529b9d459 322 Pfam PF00561 alpha/beta hydrolase fold 68 278 5.5E-9 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS29650 b35dcc3170893e8af10c4c3529b9d459 322 Gene3D G3DSA:3.40.50.1820 13 308 1.3E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 SUPERFAMILY SSF47413 7 62 1.48E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 SUPERFAMILY SSF53822 85 308 1.3E-20 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 Pfam PF13377 Periplasmic binding protein-like domain 178 327 3.0E-15 T 28-03-2018 CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 Gene3D G3DSA:3.40.50.2300 60 184 2.6E-19 T 28-03-2018 CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 SMART SM00354 4 83 1.4E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 9 54 4.8E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 Gene3D G3DSA:3.40.50.2300 185 307 1.2E-12 T 28-03-2018 CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 Gene3D G3DSA:1.10.10.10 2 19 0.34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17145 4dc26f4a3beb577a96ddea230697a6e6 333 Gene3D G3DSA:1.10.260.40 20 59 5.7E-19 T 28-03-2018 CNX65_RS03210 7a99919c31dc9458154438414873f534 590 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03210 7a99919c31dc9458154438414873f534 590 SMART SM00382 311 481 4.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03210 7a99919c31dc9458154438414873f534 590 SMART SM00382 29 207 1.3E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03210 7a99919c31dc9458154438414873f534 590 ProSitePatterns PS00211 ABC transporters family signature. 409 423 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03210 7a99919c31dc9458154438414873f534 590 Gene3D G3DSA:3.40.50.300 270 517 2.3E-54 T 28-03-2018 CNX65_RS03210 7a99919c31dc9458154438414873f534 590 SUPERFAMILY SSF52540 271 498 1.8E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03210 7a99919c31dc9458154438414873f534 590 SUPERFAMILY SSF52540 4 204 4.88E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03210 7a99919c31dc9458154438414873f534 590 Gene3D G3DSA:3.40.50.300 1 269 7.6E-54 T 28-03-2018 CNX65_RS03210 7a99919c31dc9458154438414873f534 590 Pfam PF00005 ABC transporter 303 437 4.0E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03210 7a99919c31dc9458154438414873f534 590 Pfam PF00005 ABC transporter 20 155 1.9E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS33390 c4f066e2c829d2f5e6d0ba9bdb4962b2 128 SMART SM00530 19 74 2.2E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS33390 c4f066e2c829d2f5e6d0ba9bdb4962b2 128 Pfam PF01381 Helix-turn-helix 20 72 1.2E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS33390 c4f066e2c829d2f5e6d0ba9bdb4962b2 128 Gene3D G3DSA:1.10.260.40 16 116 1.4E-16 T 28-03-2018 CNX65_RS33390 c4f066e2c829d2f5e6d0ba9bdb4962b2 128 SUPERFAMILY SSF47413 16 76 2.82E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS01310 f8c7858fff09c01fbac09f637856ee37 484 Gene3D G3DSA:3.40.50.1390 1 163 1.3E-38 T 28-03-2018 CNX65_RS01310 f8c7858fff09c01fbac09f637856ee37 484 Pfam PF07508 Recombinase 173 257 1.5E-6 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CNX65_RS01310 f8c7858fff09c01fbac09f637856ee37 484 SUPERFAMILY SSF53041 5 155 2.75E-26 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS01310 f8c7858fff09c01fbac09f637856ee37 484 Gene3D G3DSA:1.20.120.330 342 415 7.6E-4 T 28-03-2018 CNX65_RS01310 f8c7858fff09c01fbac09f637856ee37 484 Pfam PF00239 Resolvase, N terminal domain 7 155 4.5E-29 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS01310 f8c7858fff09c01fbac09f637856ee37 484 SMART SM00857 6 155 4.0E-41 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS15005 1f7d025f7d9bc551c73b7ff6a1d356ca 221 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 17 66 5.3E-10 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS02490 82733094e2f024ab8966643d58ab5eb6 142 Gene3D G3DSA:1.10.10.10 3 108 7.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02490 82733094e2f024ab8966643d58ab5eb6 142 SMART SM00347 26 126 8.4E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS02490 82733094e2f024ab8966643d58ab5eb6 142 SUPERFAMILY SSF46785 7 137 4.03E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02490 82733094e2f024ab8966643d58ab5eb6 142 Pfam PF01047 MarR family 33 90 1.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS02490 82733094e2f024ab8966643d58ab5eb6 142 Gene3D G3DSA:1.10.287.100 109 140 1.2E-12 T 28-03-2018 CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 78 93 1.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 97 113 1.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 61 77 1.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 128 148 1.9E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 SUPERFAMILY SSF46785 9 152 1.77E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 Gene3D G3DSA:1.10.10.10 2 155 7.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 Pfam PF01047 MarR family 42 100 1.8E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS20920 d029d350bb0250dcda65985b4541f877 166 SMART SM00347 35 138 1.4E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 Gene3D G3DSA:2.20.230.10 310 382 9.8E-17 T 28-03-2018 CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 SMART SM01208 311 389 2.0E-21 T 28-03-2018 IPR011098 G5 domain CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 Gene3D G3DSA:1.10.530.10 383 474 7.1E-30 T 28-03-2018 CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 Pfam PF03990 Domain of unknown function (DUF348) 265 298 4.0E-7 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 Pfam PF03990 Domain of unknown function (DUF348) 142 181 5.7E-15 T 28-03-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 SUPERFAMILY SSF53955 391 474 1.05E-29 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 Pfam PF06737 Transglycosylase-like domain 394 468 6.5E-30 T 28-03-2018 IPR010618 Transglycosylase-like CNX65_RS03180 934cfc5b6eeb711e05c3b2853a80d10e 474 Pfam PF07501 G5 domain 318 388 4.2E-16 T 28-03-2018 IPR011098 G5 domain CNX65_RS03550 017a10484b80c88de5218159ef2806e6 208 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 1 205 9.5E-58 T 28-03-2018 IPR005744 Hly-III GO:0016021|GO:0019835 CNX65_RS03550 017a10484b80c88de5218159ef2806e6 208 Pfam PF03006 Haemolysin-III related 2 199 2.3E-44 T 28-03-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 CNX65_RS12810 79f1d51ecadc13402858bc814504bcc7 533 Gene3D G3DSA:2.40.10.10 98 200 5.3E-6 T 28-03-2018 CNX65_RS12810 79f1d51ecadc13402858bc814504bcc7 533 Gene3D G3DSA:2.40.10.10 8 90 1.7E-6 T 28-03-2018 CNX65_RS12810 79f1d51ecadc13402858bc814504bcc7 533 Pfam PF13365 Trypsin-like peptidase domain 28 169 1.2E-9 T 28-03-2018 CNX65_RS12810 79f1d51ecadc13402858bc814504bcc7 533 SUPERFAMILY SSF50494 14 189 4.43E-14 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 Gene3D G3DSA:1.10.8.70 340 389 4.3E-8 T 28-03-2018 IPR020752 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 1 GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 9 493 31.051 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 Gene3D G3DSA:1.10.10.350 392 494 2.2E-26 T 28-03-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 Gene3D G3DSA:1.10.1160.10 255 338 9.4E-29 T 28-03-2018 IPR020061 Glutamyl/glutaminyl-tRNA synthetase, class Ib, alpha-bundle domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 SUPERFAMILY SSF48163 323 493 7.72E-36 T 28-03-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 SUPERFAMILY SSF52374 10 322 1.26E-100 T 28-03-2018 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 Gene3D G3DSA:3.40.50.620 10 126 2.3E-30 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 9 491 7.1E-128 T 28-03-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 Gene3D G3DSA:3.40.50.620 127 254 1.8E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 9 326 6.1E-81 T 28-03-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0005524|GO:0016876|GO:0043039 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 27 38 1.9E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 42 55 1.9E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 213 221 1.9E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 197 207 1.9E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CNX65_RS29560 cff6451dd784d6f4ab63e71c7f23d9be 496 PRINTS PR00987 Glutamyl-tRNA synthetase signature 13 25 1.9E-22 T 28-03-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0005524|GO:0005737|GO:0016876|GO:0043039 CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 SUPERFAMILY SSF46894 140 239 7.37E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 SUPERFAMILY SSF52172 15 139 4.98E-40 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 Gene3D G3DSA:1.10.10.10 138 244 5.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 Pfam PF00072 Response regulator receiver domain 20 128 6.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 SMART SM00862 163 239 3.8E-18 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 Pfam PF00486 Transcriptional regulatory protein, C terminal 164 238 2.1E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 Gene3D G3DSA:3.40.50.2300 14 137 2.2E-36 T 28-03-2018 CNX65_RS11240 ca857bd7287804aa67f078ab6f1f19bd 244 SMART SM00448 18 128 3.7E-41 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS13395 a41e07a4eca1f7a8e29843fafec804e0 188 Gene3D G3DSA:3.30.1310.10 11 115 1.8E-15 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS13395 a41e07a4eca1f7a8e29843fafec804e0 188 Pfam PF02575 YbaB/EbfC DNA-binding family 24 101 9.2E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS13395 a41e07a4eca1f7a8e29843fafec804e0 188 SUPERFAMILY SSF82607 27 105 2.09E-6 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS19155 10f7e14434599f0cc6a467cfc14caab7 384 Pfam PF01040 UbiA prenyltransferase family 111 344 4.2E-16 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CNX65_RS03840 e1e21081ec58065a7112951c142c6ae7 115 SUPERFAMILY SSF46785 2 103 1.05E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03840 e1e21081ec58065a7112951c142c6ae7 115 Gene3D G3DSA:1.10.10.10 1 106 1.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03840 e1e21081ec58065a7112951c142c6ae7 115 Pfam PF03551 Transcriptional regulator PadR-like family 14 86 1.3E-20 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS07025 b4d8f296a93679aa07854da0a251b7af 64 Pfam PF11248 Protein of unknown function (DUF3046) 1 62 1.8E-27 T 28-03-2018 IPR021408 Protein of unknown function DUF3046 CNX65_RS31045 82206538d631d47bdc2a798401f62456 248 Gene3D G3DSA:3.40.1280.10 83 248 2.5E-41 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CNX65_RS31045 82206538d631d47bdc2a798401f62456 248 SUPERFAMILY SSF55315 6 82 1.13E-11 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS31045 82206538d631d47bdc2a798401f62456 248 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 12 86 4.4E-14 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CNX65_RS31045 82206538d631d47bdc2a798401f62456 248 SUPERFAMILY SSF75217 93 246 9.81E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CNX65_RS31045 82206538d631d47bdc2a798401f62456 248 Gene3D G3DSA:3.30.1330.30 4 82 5.3E-14 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS31045 82206538d631d47bdc2a798401f62456 248 Pfam PF00588 SpoU rRNA Methylase family 102 240 3.3E-33 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CNX65_RS31045 82206538d631d47bdc2a798401f62456 248 SMART SM00967 11 88 1.1E-11 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 SUPERFAMILY SSF47203 235 381 9.21E-9 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 244 372 1.9E-18 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 SUPERFAMILY SSF56645 9 210 4.84E-29 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 105 1.2E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 PIRSF PIRSF016578 1 395 1.2E-90 T 28-03-2018 CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 Gene3D G3DSA:1.20.140.10 211 394 3.5E-10 T 28-03-2018 CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 Gene3D G3DSA:2.40.110.10 114 210 8.6E-11 T 28-03-2018 CNX65_RS23435 32d439a2b14051d5c54a41d8bc465fc5 395 Gene3D G3DSA:1.10.540.10 2 113 2.6E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS06590 6747aeef6abbddaa58428ecb7678f984 144 Pfam PF11253 Protein of unknown function (DUF3052) 13 137 5.7E-58 T 28-03-2018 IPR021412 Protein of unknown function DUF3052 CNX65_RS26355 544ab6149883f32f7a896de6ef99e6bd 190 Hamap MF_00202 Isopentenyl-diphosphate Delta-isomerase [idi]. 2 175 34.426 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CNX65_RS26355 544ab6149883f32f7a896de6ef99e6bd 190 Gene3D G3DSA:3.90.79.10 29 172 1.3E-28 T 28-03-2018 CNX65_RS26355 544ab6149883f32f7a896de6ef99e6bd 190 Pfam PF00293 NUDIX domain 29 159 9.4E-20 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS26355 544ab6149883f32f7a896de6ef99e6bd 190 TIGRFAM TIGR02150 IPP_isom_1: isopentenyl-diphosphate delta-isomerase 4 163 2.4E-46 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CNX65_RS26355 544ab6149883f32f7a896de6ef99e6bd 190 SUPERFAMILY SSF55811 2 169 7.58E-46 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS26355 544ab6149883f32f7a896de6ef99e6bd 190 PIRSF PIRSF018427 1 185 6.4E-56 T 28-03-2018 IPR011876 Isopentenyl-diphosphate delta-isomerase, type 1 GO:0004452|GO:0008299 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922|Reactome: R-HSA-191273 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 SUPERFAMILY SSF55874 282 453 7.86E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 SUPERFAMILY SSF52172 462 578 3.27E-12 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 Pfam PF00072 Response regulator receiver domain 464 557 4.6E-6 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 SMART SM00388 225 293 2.0E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 SMART SM00387 339 454 6.3E-34 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 Gene3D G3DSA:1.10.287.130 226 289 1.8E-13 T 28-03-2018 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 Gene3D G3DSA:3.40.50.2300 462 594 2.1E-10 T 28-03-2018 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 Pfam PF00512 His Kinase A (phospho-acceptor) domain 225 293 1.4E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 Gene3D G3DSA:3.30.565.10 298 461 5.5E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 379 393 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 414 432 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 438 451 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 407 4.7E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 Gene3D G3DSA:1.10.287.510 128 225 0.0019 T 28-03-2018 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 SUPERFAMILY SSF47384 208 294 4.71E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS18720 c8c40bb29f08910b246661091c29a57b 616 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 453 1.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 Gene3D G3DSA:3.90.1150.10 296 388 2.7E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 198 221 7.4E-11 T 28-03-2018 CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 162 186 7.4E-11 T 28-03-2018 CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 90 110 7.4E-11 T 28-03-2018 CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 112 133 7.4E-11 T 28-03-2018 CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 Gene3D G3DSA:3.40.640.10 43 295 2.3E-65 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 SUPERFAMILY SSF53383 9 388 1.58E-104 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS33405 fb4556fe7876966ac0e8f2e15004cf16 390 Pfam PF00155 Aminotransferase class I and II 31 385 7.8E-61 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Gene3D G3DSA:3.40.50.980 150 315 5.4E-40 T 28-03-2018 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 SUPERFAMILY SSF56801 12 515 1.83E-115 T 28-03-2018 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Gene3D G3DSA:3.40.50.980 16 149 2.9E-23 T 28-03-2018 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 ProSitePatterns PS00455 Putative AMP-binding domain signature. 149 160 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Gene3D G3DSA:2.30.38.10 316 392 7.0E-16 T 28-03-2018 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Gene3D G3DSA:1.10.1200.10 510 574 2.2E-17 T 28-03-2018 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 ProSitePatterns PS00012 Phosphopantetheine attachment site. 527 542 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Pfam PF13193 AMP-binding enzyme C-terminal domain 407 478 2.0E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Pfam PF00550 Phosphopantetheine attachment site 506 568 7.2E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 SMART SM00823 Phosphopantetheine attachment site 503 572 7.6E-11 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 SUPERFAMILY SSF47336 499 571 2.09E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Pfam PF00501 AMP-binding enzyme 24 399 3.8E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS16920 7afb6ca6d4caf0d7443267f7a274e5f1 575 Gene3D G3DSA:3.30.300.30 394 509 2.5E-25 T 28-03-2018 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 Pfam PF13450 NAD(P)-binding Rossmann-like domain 10 79 5.8E-18 T 28-03-2018 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 SUPERFAMILY SSF54373 254 325 1.31E-24 T 28-03-2018 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 TIGRFAM TIGR00031 UDP-GALP_mutase: UDP-galactopyranose mutase 6 379 2.4E-105 T 28-03-2018 IPR004379 UDP-galactopyranose mutase GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 Pfam PF03275 UDP-galactopyranose mutase 154 361 1.7E-83 T 28-03-2018 IPR015899 UDP-galactopyranose mutase, C-terminal GO:0008767 KEGG: 00052+5.4.99.9|KEGG: 00520+5.4.99.9|MetaCyc: PWY-6397|MetaCyc: PWY-7328|MetaCyc: PWY-7622 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 SUPERFAMILY SSF51971 346 376 4.41E-48 T 28-03-2018 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 SUPERFAMILY SSF51971 6 273 4.41E-48 T 28-03-2018 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 Gene3D G3DSA:3.40.50.720 5 298 1.6E-43 T 28-03-2018 CNX65_RS00650 35febd5ede66014e19509a3ff240592a 394 Gene3D G3DSA:3.40.50.720 299 383 7.9E-11 T 28-03-2018 CNX65_RS27305 5560dd182cb3410b3f5cc43dd0512679 464 PIRSF PIRSF002746 7 464 6.6E-151 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CNX65_RS27305 5560dd182cb3410b3f5cc43dd0512679 464 Pfam PF02447 GntP family permease 18 463 8.5E-130 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CNX65_RS27305 5560dd182cb3410b3f5cc43dd0512679 464 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 15 464 1.9E-116 T 28-03-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 CNX65_RS21405 3aa44a722604e0ba175f3313052d2a4c 229 Pfam PF10067 Predicted membrane protein (DUF2306) 58 204 6.7E-34 T 28-03-2018 IPR018750 Protein of unknown function DUF2306, membrane CNX65_RS26015 5c9768ed238935c1684b9611f70a8623 191 Pfam PF04542 Sigma-70 region 2 31 99 9.8E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26015 5c9768ed238935c1684b9611f70a8623 191 SUPERFAMILY SSF88659 128 185 3.36E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26015 5c9768ed238935c1684b9611f70a8623 191 Gene3D G3DSA:1.10.10.10 112 189 2.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26015 5c9768ed238935c1684b9611f70a8623 191 SUPERFAMILY SSF88946 17 113 1.07E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26015 5c9768ed238935c1684b9611f70a8623 191 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 184 6.7E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26015 5c9768ed238935c1684b9611f70a8623 191 Gene3D G3DSA:1.10.1740.10 10 95 5.8E-17 T 28-03-2018 CNX65_RS26015 5c9768ed238935c1684b9611f70a8623 191 Pfam PF08281 Sigma-70, region 4 132 183 1.2E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34670 345ec446484d9499ef064aa9e03886da 234 Pfam PF02390 Putative methyltransferase 62 225 2.1E-53 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CNX65_RS34670 345ec446484d9499ef064aa9e03886da 234 Gene3D G3DSA:3.40.50.150 25 234 3.8E-32 T 28-03-2018 CNX65_RS34670 345ec446484d9499ef064aa9e03886da 234 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 52 234 9.7E-48 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CNX65_RS34670 345ec446484d9499ef064aa9e03886da 234 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 19 234 28.855 T 28-03-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 CNX65_RS34670 345ec446484d9499ef064aa9e03886da 234 SUPERFAMILY SSF53335 10 227 4.62E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS27620 c17e0f31e7d9f4bb1c21324ae2b93fce 743 Pfam PF05729 NACHT domain 130 222 3.1E-7 T 28-03-2018 CNX65_RS27620 c17e0f31e7d9f4bb1c21324ae2b93fce 743 Gene3D G3DSA:3.40.50.300 65 615 3.9E-6 T 28-03-2018 CNX65_RS27620 c17e0f31e7d9f4bb1c21324ae2b93fce 743 SUPERFAMILY SSF52540 67 98 1.1E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27620 c17e0f31e7d9f4bb1c21324ae2b93fce 743 SUPERFAMILY SSF52540 125 219 1.1E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27055 85453e0782bd673b95a423bbcdf333bd 213 Pfam PF00293 NUDIX domain 50 161 1.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS27055 85453e0782bd673b95a423bbcdf333bd 213 SUPERFAMILY SSF55811 15 183 4.06E-41 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS27055 85453e0782bd673b95a423bbcdf333bd 213 Gene3D G3DSA:3.90.79.10 9 188 2.0E-33 T 28-03-2018 CNX65_RS21435 c654f8714d5ec1015a9254633210b094 331 SUPERFAMILY SSF53474 32 174 7.76E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21435 c654f8714d5ec1015a9254633210b094 331 SUPERFAMILY SSF53474 244 295 7.76E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21435 c654f8714d5ec1015a9254633210b094 331 Pfam PF12146 Serine aminopeptidase, S33 59 283 2.1E-8 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CNX65_RS21435 c654f8714d5ec1015a9254633210b094 331 Gene3D G3DSA:3.40.50.1820 28 328 1.5E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20345 839f78414c772e4b57b857e1afc4039e 195 Gene3D G3DSA:1.10.357.10 61 192 6.5E-24 T 28-03-2018 CNX65_RS20345 839f78414c772e4b57b857e1afc4039e 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 5.8E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20345 839f78414c772e4b57b857e1afc4039e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 14 27 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20345 839f78414c772e4b57b857e1afc4039e 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 58 1.1E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20345 839f78414c772e4b57b857e1afc4039e 195 Gene3D G3DSA:1.10.10.60 1 60 1.5E-19 T 28-03-2018 CNX65_RS20345 839f78414c772e4b57b857e1afc4039e 195 SUPERFAMILY SSF46689 2 76 1.33E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS20345 839f78414c772e4b57b857e1afc4039e 195 SUPERFAMILY SSF48498 79 192 4.45E-25 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 Gene3D G3DSA:3.40.50.200 167 478 4.8E-90 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 PRINTS PR00723 Subtilisin serine protease family (S8) signature 243 256 7.4E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 PRINTS PR00723 Subtilisin serine protease family (S8) signature 206 225 7.4E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 PRINTS PR00723 Subtilisin serine protease family (S8) signature 412 428 7.4E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 SUPERFAMILY SSF52743 189 471 1.44E-83 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 247 257 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 Pfam PF00082 Subtilase family 206 451 2.1E-55 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS14925 ee5cf4a1ce6f9b57ea5f75e8a57d72a0 957 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 413 423 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS01060 78e861496861c583ade38ed00f244b99 350 Pfam PF07859 alpha/beta hydrolase fold 116 321 1.3E-72 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CNX65_RS01060 78e861496861c583ade38ed00f244b99 350 SUPERFAMILY SSF53474 85 341 1.91E-70 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS01060 78e861496861c583ade38ed00f244b99 350 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 116 132 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CNX65_RS01060 78e861496861c583ade38ed00f244b99 350 Gene3D G3DSA:3.40.50.1820 42 346 4.8E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20545 bf55a94666f86431f39c423979c23f86 343 SUPERFAMILY SSF69118 18 169 8.64E-24 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS20545 bf55a94666f86431f39c423979c23f86 343 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 79 108 1.1E-7 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS20545 bf55a94666f86431f39c423979c23f86 343 Pfam PF02627 Carboxymuconolactone decarboxylase family 64 106 3.0E-5 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS20545 bf55a94666f86431f39c423979c23f86 343 Gene3D G3DSA:1.20.1290.10 220 338 2.4E-7 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS20545 bf55a94666f86431f39c423979c23f86 343 Gene3D G3DSA:1.20.1290.10 12 172 1.0E-25 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 132 1.2E-31 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 SUPERFAMILY SSF50129 2 173 3.04E-51 T 28-03-2018 IPR011032 GroES-like CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 Gene3D G3DSA:3.90.180.10 1 159 1.5E-43 T 28-03-2018 CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 SMART SM00829 10 338 0.0022 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 Gene3D G3DSA:3.40.50.720 160 286 3.3E-24 T 28-03-2018 CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 Pfam PF00107 Zinc-binding dehydrogenase 174 299 6.2E-21 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 SUPERFAMILY SSF51735 142 296 9.6E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34895 0cdd4f3dd0c8c0acabfdad6dc4486d72 344 Hamap MF_00627 L-threonine 3-dehydrogenase [tdh]. 1 340 56.093 T 28-03-2018 IPR004627 L-threonine 3-dehydrogenase GO:0006567|GO:0008270|GO:0008743|GO:0055114 KEGG: 00040+1.1.1.10|KEGG: 00260+1.1.1.103|MetaCyc: PWY-5515|MetaCyc: PWY-5525|MetaCyc: PWY-7378 CNX65_RS10965 8568916b70f5a4fb6e73ddd3cce81cc1 308 SUPERFAMILY SSF53850 25 305 5.83E-42 T 28-03-2018 CNX65_RS10965 8568916b70f5a4fb6e73ddd3cce81cc1 308 Gene3D G3DSA:3.40.190.10 24 150 3.5E-11 T 28-03-2018 CNX65_RS10965 8568916b70f5a4fb6e73ddd3cce81cc1 308 Pfam PF16868 NMT1-like family 55 305 6.1E-35 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS10965 8568916b70f5a4fb6e73ddd3cce81cc1 308 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 8 305 5.9E-46 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS10965 8568916b70f5a4fb6e73ddd3cce81cc1 308 Gene3D G3DSA:3.40.190.10 151 306 2.7E-25 T 28-03-2018 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 Gene3D G3DSA:3.40.50.300 530 755 2.1E-7 T 28-03-2018 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 SUPERFAMILY SSF48452 128 296 1.31E-38 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 SMART SM01043 133 278 9.9E-50 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 Pfam PF03704 Bacterial transcriptional activator domain 133 278 3.1E-49 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 Gene3D G3DSA:1.25.40.10 130 303 5.7E-28 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 Gene3D G3DSA:1.10.10.10 23 129 4.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 Pfam PF13191 AAA ATPase domain 529 709 2.6E-18 T 28-03-2018 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 SUPERFAMILY SSF46894 33 126 2.83E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 SUPERFAMILY SSF55073 360 502 2.83E-11 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 SMART SM00862 47 126 2.0E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 Pfam PF00486 Transcriptional regulatory protein, C terminal 55 114 1.4E-5 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 SUPERFAMILY SSF52540 645 786 1.54E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 SUPERFAMILY SSF52540 529 579 1.54E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16225 b5397c52da90f35fd13228bb40e2d6af 945 Gene3D G3DSA:3.30.70.1230 347 506 4.2E-12 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 Pfam PF00425 chorismate binding enzyme 131 388 7.7E-44 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00097 Anthranilate synthase component II signature 527 538 1.0E-6 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00097 Anthranilate synthase component II signature 613 626 1.0E-6 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00097 Anthranilate synthase component II signature 453 467 1.0E-6 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 Gene3D G3DSA:3.60.120.10 8 399 2.9E-75 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00096 Glutamine amidotransferase superfamily signature 494 503 3.8E-9 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00096 Glutamine amidotransferase superfamily signature 613 626 3.8E-9 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00096 Glutamine amidotransferase superfamily signature 527 538 3.8E-9 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 SUPERFAMILY SSF52317 449 633 3.6E-26 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 SUPERFAMILY SSF56322 86 398 4.58E-64 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 Pfam PF00117 Glutamine amidotransferase class-I 455 630 5.4E-23 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 491 505 8.3E-5 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 527 543 8.3E-5 T 28-03-2018 CNX65_RS15955 643b4dba5c421e9d987c09993ba6c8bb 649 Gene3D G3DSA:3.40.50.880 452 646 5.7E-33 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS04270 4899f5f254ca6a25c2869488f579d68d 319 SUPERFAMILY SSF55811 131 296 2.98E-42 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS04270 4899f5f254ca6a25c2869488f579d68d 319 Gene3D G3DSA:3.90.79.10 178 318 1.6E-32 T 28-03-2018 CNX65_RS04270 4899f5f254ca6a25c2869488f579d68d 319 Pfam PF09296 NADH pyrophosphatase-like rudimentary NUDIX domain 53 143 7.7E-9 T 28-03-2018 IPR015375 NADH pyrophosphatase-like, N-terminal GO:0016787 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CNX65_RS04270 4899f5f254ca6a25c2869488f579d68d 319 ProSitePatterns PS00893 Nudix box signature. 212 233 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS04270 4899f5f254ca6a25c2869488f579d68d 319 Pfam PF09297 NADH pyrophosphatase zinc ribbon domain 145 176 1.1E-10 T 28-03-2018 IPR015376 Zinc ribbon, NADH pyrophosphatase GO:0016787|GO:0046872 KEGG: 00760+3.6.1.22|MetaCyc: PWY-5381|MetaCyc: PWY-7761 CNX65_RS04270 4899f5f254ca6a25c2869488f579d68d 319 Pfam PF00293 NUDIX domain 181 290 6.1E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS11235 eee08e16a212dafeb2db1054eb322091 293 Gene3D G3DSA:2.10.109.10 137 242 2.8E-9 T 28-03-2018 CNX65_RS11235 eee08e16a212dafeb2db1054eb322091 293 SUPERFAMILY SSF51306 154 205 3.5E-8 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS11235 eee08e16a212dafeb2db1054eb322091 293 Pfam PF00717 Peptidase S24-like 157 224 1.6E-7 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS11235 eee08e16a212dafeb2db1054eb322091 293 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 155 170 2.3E-5 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CNX65_RS11235 eee08e16a212dafeb2db1054eb322091 293 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 214 225 2.3E-5 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CNX65_RS11235 eee08e16a212dafeb2db1054eb322091 293 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 129 272 1.3E-17 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CNX65_RS06070 d87559442cc8982e88b33322a7108a26 147 Gene3D G3DSA:2.30.30.110 37 147 1.3E-16 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CNX65_RS06070 d87559442cc8982e88b33322a7108a26 147 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 39 141 1.1E-8 T 28-03-2018 IPR003477 mRNA interferase PemK-like GO:0003677 CNX65_RS06070 d87559442cc8982e88b33322a7108a26 147 SUPERFAMILY SSF50118 36 141 1.37E-8 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CNX65_RS09905 04a078cf21a0f6c544fbdf7ab4ca0e60 327 SUPERFAMILY SSF53474 4 128 1.36E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09905 04a078cf21a0f6c544fbdf7ab4ca0e60 327 SUPERFAMILY SSF53474 155 322 1.36E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09905 04a078cf21a0f6c544fbdf7ab4ca0e60 327 Gene3D G3DSA:3.40.50.1820 1 322 3.6E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09905 04a078cf21a0f6c544fbdf7ab4ca0e60 327 Pfam PF05448 Acetyl xylan esterase (AXE1) 2 318 1.4E-92 T 28-03-2018 IPR008391 Acetyl xylan esterase CNX65_RS11655 2a6f5838df61ea1bc895c6ddc6b8f10d 257 Pfam PF12822 ECF transporter, substrate-specific component 72 236 1.3E-18 T 28-03-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 CNX65_RS11655 2a6f5838df61ea1bc895c6ddc6b8f10d 257 PIRSF PIRSF037395 2 257 2.9E-94 T 28-03-2018 IPR017196 ECF transporter, predicted substrate-specific component UCP037395 CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 49 308 3.5E-71 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 Gene3D G3DSA:1.20.1640.10 75 332 8.4E-26 T 28-03-2018 CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 Pfam PF02355 Protein export membrane protein 135 317 1.2E-56 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 74 305 5.4E-51 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 PRINTS PR01755 Bacterial translocase SecF protein signature 168 182 3.4E-24 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 PRINTS PR01755 Bacterial translocase SecF protein signature 48 63 3.4E-24 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 PRINTS PR01755 Bacterial translocase SecF protein signature 216 234 3.4E-24 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 PRINTS PR01755 Bacterial translocase SecF protein signature 251 266 3.4E-24 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 21 319 24.217 T 28-03-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 Pfam PF07549 SecD/SecF GG Motif 45 68 1.5E-9 T 28-03-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site CNX65_RS08465 8bf50d3238b8d4eb3535db0cb7b9ca59 396 SUPERFAMILY SSF82866 140 316 2.49E-27 T 28-03-2018 CNX65_RS29360 33615fb36422c2850da04541599400de 733 Gene3D G3DSA:3.40.50.300 255 470 2.0E-36 T 28-03-2018 CNX65_RS29360 33615fb36422c2850da04541599400de 733 Pfam PF00270 DEAD/DEAH box helicase 295 449 2.6E-16 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS29360 33615fb36422c2850da04541599400de 733 Pfam PF00271 Helicase conserved C-terminal domain 548 620 6.0E-17 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS29360 33615fb36422c2850da04541599400de 733 Pfam PF17191 RecG wedge domain 13 180 2.2E-12 T 28-03-2018 IPR033454 RecG, wedge domain CNX65_RS29360 33615fb36422c2850da04541599400de 733 SMART SM00487 270 473 2.7E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS29360 33615fb36422c2850da04541599400de 733 SUPERFAMILY SSF50249 12 184 4.16E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS29360 33615fb36422c2850da04541599400de 733 SUPERFAMILY SSF52540 190 466 1.87E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29360 33615fb36422c2850da04541599400de 733 SMART SM00490 536 621 9.7E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS29360 33615fb36422c2850da04541599400de 733 SUPERFAMILY SSF52540 404 630 4.87E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29360 33615fb36422c2850da04541599400de 733 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 24 696 3.2E-203 T 28-03-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 CNX65_RS29360 33615fb36422c2850da04541599400de 733 Gene3D G3DSA:3.40.50.300 475 662 2.2E-30 T 28-03-2018 CNX65_RS29360 33615fb36422c2850da04541599400de 733 Gene3D G3DSA:2.40.50.140 43 143 3.1E-23 T 28-03-2018 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 SMART SM01350 162 296 8.3E-4 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 SUPERFAMILY SSF51735 2 144 1.81E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 230 242 - T 28-03-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 143 7.3E-35 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 Gene3D G3DSA:3.40.50.720 2 163 1.5E-32 T 28-03-2018 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 162 272 2.2E-22 T 28-03-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 Gene3D G3DSA:1.10.1040.10 164 295 1.0E-38 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 SUPERFAMILY SSF48179 160 292 2.38E-39 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 TIGRFAM TIGR00872 gnd_rel: 6-phosphogluconate dehydrogenase (decarboxylating) 2 292 4.1E-105 T 28-03-2018 IPR004849 6-phosphogluconate dehydrogenase, YqeC-type GO:0055114 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 50 79 4.0E-33 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 226 253 4.0E-33 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 103 128 4.0E-33 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 1 15 4.0E-33 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS00015 ff9161fd9535e3baa6066020d7ddeabf 304 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 151 179 4.0E-33 T 28-03-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 CNX65_RS01035 f436361e1f30f71493b87e343915c031 392 Pfam PF07690 Major Facilitator Superfamily 19 210 1.4E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS01035 f436361e1f30f71493b87e343915c031 392 Pfam PF07690 Major Facilitator Superfamily 212 386 2.5E-8 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS01035 f436361e1f30f71493b87e343915c031 392 Gene3D G3DSA:1.20.1250.20 2 190 6.3E-20 T 28-03-2018 CNX65_RS01035 f436361e1f30f71493b87e343915c031 392 Gene3D G3DSA:1.20.1250.20 204 389 4.1E-14 T 28-03-2018 CNX65_RS01035 f436361e1f30f71493b87e343915c031 392 SUPERFAMILY SSF103473 10 382 1.44E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS29570 bfa1db0cde34aeca25d7ff50f7b91f9f 256 Pfam PF10370 Domain of unknown function (DUF2437) 2 54 1.6E-14 T 28-03-2018 IPR018833 Domain of unknown function DUF2437 CNX65_RS29570 bfa1db0cde34aeca25d7ff50f7b91f9f 256 Gene3D G3DSA:3.90.850.10 27 256 4.9E-85 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS29570 bfa1db0cde34aeca25d7ff50f7b91f9f 256 SUPERFAMILY SSF56529 51 253 7.2E-76 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS29570 bfa1db0cde34aeca25d7ff50f7b91f9f 256 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 59 252 3.1E-62 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS33330 71261126f9f82750fc12297bddb308b0 165 Pfam PF10698 Protein of unknown function (DUF2505) 9 161 1.2E-47 T 28-03-2018 IPR019639 Protein of unknown function DUF2505 CNX65_RS33330 71261126f9f82750fc12297bddb308b0 165 Gene3D G3DSA:3.30.530.20 1 163 2.5E-8 T 28-03-2018 IPR023393 START-like domain CNX65_RS29410 59088ec19b836bc5ac11a1e05280e271 77 SUPERFAMILY SSF54909 2 76 7.24E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS29410 59088ec19b836bc5ac11a1e05280e271 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 75 5.3E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS29410 59088ec19b836bc5ac11a1e05280e271 77 Gene3D G3DSA:3.30.70.920 1 77 3.8E-17 T 28-03-2018 CNX65_RS13675 1cd9887dfadebdb47d2b84113cf3e41f 357 Gene3D G3DSA:3.40.50.1110 42 342 2.2E-27 T 28-03-2018 CNX65_RS13675 1cd9887dfadebdb47d2b84113cf3e41f 357 SUPERFAMILY SSF52266 48 335 2.83E-37 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS13675 1cd9887dfadebdb47d2b84113cf3e41f 357 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 52 326 2.7E-16 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS26675 a589ae7fa2c8bd8339d7345f587dc2dd 126 SUPERFAMILY SSF51230 2 125 3.27E-43 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS26675 a589ae7fa2c8bd8339d7345f587dc2dd 126 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CNX65_RS26675 a589ae7fa2c8bd8339d7345f587dc2dd 126 Gene3D G3DSA:2.40.50.100 4 126 5.3E-46 T 28-03-2018 CNX65_RS26675 a589ae7fa2c8bd8339d7345f587dc2dd 126 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 2 125 1.4E-50 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CNX65_RS26675 a589ae7fa2c8bd8339d7345f587dc2dd 126 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 3 125 38.658 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CNX65_RS26675 a589ae7fa2c8bd8339d7345f587dc2dd 126 Pfam PF01597 Glycine cleavage H-protein 6 126 2.3E-44 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CNX65_RS32965 c5d0f5ec600a74c9ef275a99d9d96335 309 SUPERFAMILY SSF47240 55 303 1.24E-67 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS32965 c5d0f5ec600a74c9ef275a99d9d96335 309 Gene3D G3DSA:1.20.1260.10 45 309 7.4E-69 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS32965 c5d0f5ec600a74c9ef275a99d9d96335 309 PIRSF PIRSF037834 49 309 1.0E-89 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CNX65_RS32965 c5d0f5ec600a74c9ef275a99d9d96335 309 Pfam PF05138 Phenylacetic acid catabolic protein 53 309 2.0E-80 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CNX65_RS32965 c5d0f5ec600a74c9ef275a99d9d96335 309 TIGRFAM TIGR02158 PA_CoA_Oxy3: phenylacetate-CoA oxygenase, PaaI subunit 64 309 6.2E-72 T 28-03-2018 IPR011882 1,2-phenylacetyl-CoA epoxidase, subunit C GO:0010124 CNX65_RS03695 4026d2d9cbc0088515e5f9c3030fd7c0 327 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03695 4026d2d9cbc0088515e5f9c3030fd7c0 327 Pfam PF00005 ABC transporter 19 160 1.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03695 4026d2d9cbc0088515e5f9c3030fd7c0 327 SUPERFAMILY SSF52540 3 235 5.09E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03695 4026d2d9cbc0088515e5f9c3030fd7c0 327 Gene3D G3DSA:3.40.50.300 1 249 1.2E-69 T 28-03-2018 CNX65_RS03695 4026d2d9cbc0088515e5f9c3030fd7c0 327 SMART SM00382 27 210 2.9E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15155 c67b9c6a16f3f831ec417ba8bf92dbf9 487 Gene3D G3DSA:3.40.50.10140 1 144 1.7E-9 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS15155 c67b9c6a16f3f831ec417ba8bf92dbf9 487 SUPERFAMILY SSF52200 2 123 3.92E-6 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS15155 c67b9c6a16f3f831ec417ba8bf92dbf9 487 Pfam PF13676 TIR domain 22 112 6.8E-12 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS17850 c1939db3ae1fe738ede813f1c49f6790 349 Gene3D G3DSA:3.20.20.30 1 342 4.7E-71 T 28-03-2018 CNX65_RS17850 c1939db3ae1fe738ede813f1c49f6790 349 TIGRFAM TIGR03559 F420_Rv3520c: probable F420-dependent oxidoreductase, Rv3520c family 2 322 1.5E-120 T 28-03-2018 IPR019951 F420-dependent oxidoreductase-predicted, Rv3520c CNX65_RS17850 c1939db3ae1fe738ede813f1c49f6790 349 Pfam PF00296 Luciferase-like monooxygenase 17 317 2.3E-83 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS17850 c1939db3ae1fe738ede813f1c49f6790 349 SUPERFAMILY SSF51679 5 329 1.83E-70 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS12850 21936705d255957e4a8a1bd1105abb72 150 SMART SM00347 28 133 2.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12850 21936705d255957e4a8a1bd1105abb72 150 Gene3D G3DSA:1.10.10.10 2 150 6.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12850 21936705d255957e4a8a1bd1105abb72 150 Pfam PF01047 MarR family 44 96 3.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12850 21936705d255957e4a8a1bd1105abb72 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 93 109 1.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12850 21936705d255957e4a8a1bd1105abb72 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 143 1.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12850 21936705d255957e4a8a1bd1105abb72 150 PRINTS PR00598 Bacterial regulatory protein MarR family signature 74 89 1.1E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12850 21936705d255957e4a8a1bd1105abb72 150 SUPERFAMILY SSF46785 13 148 1.44E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 Gene3D G3DSA:3.40.50.300 250 423 2.4E-45 T 28-03-2018 CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 TIGRFAM TIGR01967 DEAH_box_HrpA: RNA helicase HrpA 10 1301 0.0 T 28-03-2018 IPR010222 RNA helicase HrpA GO:0004004 CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 SMART SM00847 464 556 1.3E-35 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 Pfam PF11898 Domain of unknown function (DUF3418) 722 1302 9.2E-217 T 28-03-2018 IPR024590 RNA helicase HrpA, C-terminal CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 SUPERFAMILY SSF52540 71 596 6.88E-107 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 Pfam PF04408 Helicase associated domain (HA2) 466 563 2.1E-18 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 Gene3D G3DSA:3.40.50.300 73 232 1.3E-29 T 28-03-2018 CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 SMART SM00490 304 404 4.7E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 SMART SM00382 89 384 4.0E-5 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 Pfam PF00270 DEAD/DEAH box helicase 81 230 6.4E-6 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 Pfam PF07717 Oligonucleotide/oligosaccharide-binding (OB)-fold 619 708 1.8E-16 T 28-03-2018 IPR011709 Domain of unknown function DUF1605 CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 SMART SM00487 72 256 1.2E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS17825 e012f677f3d7917a2ef709eb566a2d52 1306 Pfam PF00271 Helicase conserved C-terminal domain 286 403 1.2E-8 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 Gene3D G3DSA:1.10.10.60 47 98 1.2E-9 T 28-03-2018 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 SUPERFAMILY SSF55945 106 202 3.14E-22 T 28-03-2018 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 Gene3D G3DSA:1.10.340.30 208 352 1.3E-5 T 28-03-2018 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 SMART SM00342 9 92 1.1E-16 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 Gene3D G3DSA:3.30.310.20 106 207 1.8E-34 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 Pfam PF12833 Helix-turn-helix domain 15 92 5.3E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 SMART SM01009 106 221 1.2E-37 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 SUPERFAMILY SSF48150 213 389 1.88E-10 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 46 88 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 SUPERFAMILY SSF46689 45 94 2.33E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 Pfam PF06029 AlkA N-terminal domain 106 221 4.2E-28 T 28-03-2018 IPR010316 DNA-3-methyladenine glycosylase AlkA, N-terminal CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 Gene3D G3DSA:1.10.10.60 11 46 0.095 T 28-03-2018 CNX65_RS02870 72718ccf6f8b21212c7d1c725770a515 394 Gene3D G3DSA:1.10.1670.10 353 389 5.3E-6 T 28-03-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 CNX65_RS03945 87db8670f606543aabe6a970aebbb9d8 130 TIGRFAM TIGR01410 tatB: twin arginine-targeting protein translocase TatB 4 84 5.7E-19 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CNX65_RS03945 87db8670f606543aabe6a970aebbb9d8 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 4.1E-11 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CNX65_RS03945 87db8670f606543aabe6a970aebbb9d8 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 4.1E-11 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CNX65_RS03945 87db8670f606543aabe6a970aebbb9d8 130 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 4.1E-11 T 28-03-2018 IPR003998 Twin-arginine translocation protein TatB-like GO:0009306|GO:0016020 CNX65_RS03945 87db8670f606543aabe6a970aebbb9d8 130 Hamap MF_00237 Sec-independent protein translocase protein TatB [tatB]. 2 123 14.326 T 28-03-2018 IPR018448 Twin-arginine translocation protein TatB GO:0016020|GO:0043953 CNX65_RS03945 87db8670f606543aabe6a970aebbb9d8 130 Pfam PF02416 mttA/Hcf106 family 5 50 6.2E-7 T 28-03-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 Gene3D G3DSA:1.10.10.10 130 216 3.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 206 1.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 SMART SM00448 3 118 1.2E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 166 193 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 Pfam PF00072 Response regulator receiver domain 5 118 2.3E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 SMART SM00421 149 206 7.1E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 SUPERFAMILY SSF46894 141 213 1.19E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 Gene3D G3DSA:3.40.50.2300 2 129 4.7E-33 T 28-03-2018 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 166 182 3.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 166 3.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 182 194 3.2E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08150 48244f8590cebdc1e94154193c124e08 216 SUPERFAMILY SSF52172 3 132 1.85E-31 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 PRINTS PR00298 60kDa chaperonin signature 26 52 2.2E-68 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 PRINTS PR00298 60kDa chaperonin signature 266 289 2.2E-68 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 PRINTS PR00298 60kDa chaperonin signature 82 109 2.2E-68 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 PRINTS PR00298 60kDa chaperonin signature 396 417 2.2E-68 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 PRINTS PR00298 60kDa chaperonin signature 348 373 2.2E-68 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 Hamap MF_00600 60 kDa chaperonin [groL]. 1 539 39.309 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 28-03-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 Gene3D G3DSA:3.50.7.10 177 371 4.9E-85 T 28-03-2018 IPR027409 GroEL-like apical domain CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 SUPERFAMILY SSF54849 136 203 5.04E-22 T 28-03-2018 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 SUPERFAMILY SSF52029 183 374 2.79E-73 T 28-03-2018 IPR027409 GroEL-like apical domain CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 1.1E-86 T 28-03-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 Gene3D G3DSA:1.10.560.10 372 514 6.3E-22 T 28-03-2018 IPR027413 GroEL-like equatorial domain CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 SUPERFAMILY SSF48592 1 135 2.93E-74 T 28-03-2018 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 SUPERFAMILY SSF48592 406 522 2.93E-74 T 28-03-2018 CNX65_RS32105 721823546f8c7238bf6f9b116c5cb65e 541 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 525 3.6E-228 T 28-03-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 CNX65_RS04655 6f5a2167258cc0921beaaf50b637b526 300 PIRSF PIRSF003097 1 300 5.6E-68 T 28-03-2018 IPR004513 Cell division protein FtsX GO:0007049|GO:0016021 CNX65_RS04655 6f5a2167258cc0921beaaf50b637b526 300 Pfam PF02687 FtsX-like permease family 203 291 9.1E-6 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS32400 900e97fe7daa0d62377819b3766a0ed4 122 SMART SM01374 1 122 1.2E-86 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CNX65_RS32400 900e97fe7daa0d62377819b3766a0ed4 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 1.9E-56 T 28-03-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 CNX65_RS32400 900e97fe7daa0d62377819b3766a0ed4 122 Pfam PF00238 Ribosomal protein L14p/L23e 2 122 1.9E-54 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CNX65_RS32400 900e97fe7daa0d62377819b3766a0ed4 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 28-03-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32400 900e97fe7daa0d62377819b3766a0ed4 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.794 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CNX65_RS32400 900e97fe7daa0d62377819b3766a0ed4 122 Gene3D G3DSA:2.40.150.20 1 122 4.4E-53 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CNX65_RS32400 900e97fe7daa0d62377819b3766a0ed4 122 SUPERFAMILY SSF50193 2 122 3.53E-50 T 28-03-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 CNX65_RS31500 6c984a168ff2eaaf610f421a59313188 593 Gene3D G3DSA:3.40.50.280 463 593 5.3E-27 T 28-03-2018 CNX65_RS31500 6c984a168ff2eaaf610f421a59313188 593 Pfam PF01642 Methylmalonyl-CoA mutase 43 504 5.5E-119 T 28-03-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0008152|GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31500 6c984a168ff2eaaf610f421a59313188 593 SUPERFAMILY SSF51703 9 500 1.81E-140 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31500 6c984a168ff2eaaf610f421a59313188 593 Gene3D G3DSA:3.20.20.240 43 462 5.5E-135 T 28-03-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0008152|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 CNX65_RS31500 6c984a168ff2eaaf610f421a59313188 593 SUPERFAMILY SSF52242 448 591 3.77E-36 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS31500 6c984a168ff2eaaf610f421a59313188 593 Gene3D G3DSA:1.10.196.20 8 42 6.8E-12 T 28-03-2018 IPR024067 Methylmalonyl-CoA mutase small subunit, N-terminal KEGG: 00280+5.4.99.2|KEGG: 00630+5.4.99.2|KEGG: 00640+5.4.99.2|KEGG: 00720+5.4.99.2|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854 CNX65_RS04910 b0680813d746c37f4daa9e509dd7ffcf 763 SUPERFAMILY SSF48576 378 706 1.38E-56 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS04910 b0680813d746c37f4daa9e509dd7ffcf 763 Gene3D G3DSA:1.10.600.10 1 339 7.8E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS04910 b0680813d746c37f4daa9e509dd7ffcf 763 SUPERFAMILY SSF48576 3 334 2.65E-63 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS04910 b0680813d746c37f4daa9e509dd7ffcf 763 Gene3D G3DSA:1.10.600.10 383 716 2.8E-68 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS17140 0dd69ca1669e2c28b9eb0a477fc9ad8d 334 Gene3D G3DSA:2.115.10.20 170 330 3.9E-16 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS17140 0dd69ca1669e2c28b9eb0a477fc9ad8d 334 SUPERFAMILY SSF75005 40 267 2.62E-21 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS17140 0dd69ca1669e2c28b9eb0a477fc9ad8d 334 Gene3D G3DSA:2.115.10.20 38 169 4.8E-17 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS17895 a72a26d8a926b740f4362d2729d5d878 257 Gene3D G3DSA:3.40.50.80 131 257 3.4E-27 T 28-03-2018 CNX65_RS17895 a72a26d8a926b740f4362d2729d5d878 257 Pfam PF04954 Siderophore-interacting protein 135 236 2.9E-23 T 28-03-2018 IPR007037 Siderophore-interacting protein CNX65_RS17895 a72a26d8a926b740f4362d2729d5d878 257 Gene3D G3DSA:2.40.30.10 1 127 2.6E-30 T 28-03-2018 CNX65_RS17895 a72a26d8a926b740f4362d2729d5d878 257 Pfam PF08021 Siderophore-interacting FAD-binding domain 5 127 1.6E-33 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CNX65_RS17895 a72a26d8a926b740f4362d2729d5d878 257 SUPERFAMILY SSF63380 3 128 7.38E-11 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS27455 802303cc9748e70d1c9ed0b288e42b51 330 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 318 1.5E-117 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CNX65_RS27455 802303cc9748e70d1c9ed0b288e42b51 330 Pfam PF03741 Integral membrane protein TerC family 69 272 2.1E-51 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CNX65_RS15215 57a263e6eb00183ea746827ebec17742 207 SUPERFAMILY SSF46689 22 92 1.94E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS15215 57a263e6eb00183ea746827ebec17742 207 Gene3D G3DSA:1.10.357.10 81 206 2.4E-5 T 28-03-2018 CNX65_RS15215 57a263e6eb00183ea746827ebec17742 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 78 1.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS15215 57a263e6eb00183ea746827ebec17742 207 Gene3D G3DSA:1.10.260.40 54 80 4.9E-10 T 28-03-2018 CNX65_RS15215 57a263e6eb00183ea746827ebec17742 207 Gene3D G3DSA:1.10.10.60 12 53 3.2E-13 T 28-03-2018 CNX65_RS17665 6c8342c7362d18379eb22ab547517859 314 ProSitePatterns PS00894 DeoR-type HTH domain signature. 7 41 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CNX65_RS17665 6c8342c7362d18379eb22ab547517859 314 Gene3D G3DSA:1.10.10.10 1 68 5.7E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17665 6c8342c7362d18379eb22ab547517859 314 Pfam PF13280 WYL domain 139 308 8.1E-29 T 28-03-2018 IPR026881 WYL domain CNX65_RS17665 6c8342c7362d18379eb22ab547517859 314 SUPERFAMILY SSF46785 5 63 8.29E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17665 6c8342c7362d18379eb22ab547517859 314 Pfam PF08279 HTH domain 7 62 2.0E-16 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CNX65_RS17665 6c8342c7362d18379eb22ab547517859 314 PIRSF PIRSF016838 1 314 2.3E-22 T 28-03-2018 IPR028349 Protein PafC CNX65_RS15705 47c83494db16b9093a134b429d6fa860 385 Gene3D G3DSA:3.30.420.40 72 187 5.9E-15 T 28-03-2018 CNX65_RS15705 47c83494db16b9093a134b429d6fa860 385 Pfam PF00480 ROK family 116 359 2.8E-25 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS15705 47c83494db16b9093a134b429d6fa860 385 SUPERFAMILY SSF46785 15 70 2.73E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15705 47c83494db16b9093a134b429d6fa860 385 SUPERFAMILY SSF53067 79 366 4.11E-27 T 28-03-2018 CNX65_RS15705 47c83494db16b9093a134b429d6fa860 385 Gene3D G3DSA:3.30.420.40 188 376 6.5E-35 T 28-03-2018 CNX65_RS15705 47c83494db16b9093a134b429d6fa860 385 Gene3D G3DSA:1.10.10.10 14 71 3.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31960 8e36ac17387239d609e574f850bf5612 92 SUPERFAMILY SSF48600 15 80 8.39E-12 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS31960 8e36ac17387239d609e574f850bf5612 92 Gene3D G3DSA:1.20.59.10 3 89 5.3E-14 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS31960 8e36ac17387239d609e574f850bf5612 92 TIGRFAM TIGR01808 CM_M_hiGC-arch: chorismate mutase 16 88 3.0E-31 T 28-03-2018 IPR010958 Chorismate mutase, high GC Gram-positive bacteria/archaeal CNX65_RS31960 8e36ac17387239d609e574f850bf5612 92 Pfam PF01817 Chorismate mutase type II 20 73 1.5E-8 T 28-03-2018 IPR020822 Chorismate mutase, type II GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS31960 8e36ac17387239d609e574f850bf5612 92 SMART SM00830 20 82 2.1E-4 T 28-03-2018 IPR002701 Chorismate mutase GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 Gene3D G3DSA:3.40.50.1360 78 247 2.7E-40 T 28-03-2018 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 Gene3D G3DSA:1.10.10.10 1 77 3.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 SUPERFAMILY SSF46785 5 60 4.85E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 SUPERFAMILY SSF100950 76 236 1.15E-31 T 28-03-2018 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 SMART SM00420 6 58 7.1E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 SMART SM01134 74 236 8.5E-62 T 28-03-2018 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 6.3E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 Pfam PF00455 DeoR C terminal sensor domain 78 234 1.7E-48 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 5.4E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS03075 4be5eb2ae9cbe886a747a235e9c670f1 266 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 5.4E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 Gene3D G3DSA:1.20.970.10 1 73 2.4E-21 T 28-03-2018 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 8 340 33.825 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 SUPERFAMILY SSF52418 78 342 6.02E-78 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 11 339 2.4E-109 T 28-03-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 Pfam PF02885 Glycosyl transferase family, helical bundle domain 9 69 1.5E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 Pfam PF00591 Glycosyl transferase family, a/b domain 77 329 1.2E-77 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 SUPERFAMILY SSF47648 6 72 4.45E-18 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS06780 d10e50c1d26edcd63a88e3d1c0bcd34f 349 Gene3D G3DSA:3.40.1030.10 74 348 2.9E-92 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS15915 f3b0e9cbc938631883ca2d1f9527ed04 489 SUPERFAMILY SSF103473 273 487 3.79E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15915 f3b0e9cbc938631883ca2d1f9527ed04 489 SUPERFAMILY SSF103473 25 218 3.79E-68 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15915 f3b0e9cbc938631883ca2d1f9527ed04 489 Gene3D G3DSA:1.20.1250.20 33 218 1.7E-28 T 28-03-2018 CNX65_RS15915 f3b0e9cbc938631883ca2d1f9527ed04 489 Pfam PF07690 Major Facilitator Superfamily 42 434 9.7E-55 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS15915 f3b0e9cbc938631883ca2d1f9527ed04 489 Gene3D G3DSA:1.20.1250.20 284 489 8.6E-31 T 28-03-2018 CNX65_RS15915 f3b0e9cbc938631883ca2d1f9527ed04 489 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 36 445 1.6E-106 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CNX65_RS08895 0404ec26f45b1defe693ee75ae1219f4 424 SUPERFAMILY SSF53850 35 422 1.04E-43 T 28-03-2018 CNX65_RS08895 0404ec26f45b1defe693ee75ae1219f4 424 Gene3D G3DSA:3.40.190.10 22 188 4.1E-25 T 28-03-2018 CNX65_RS08895 0404ec26f45b1defe693ee75ae1219f4 424 Gene3D G3DSA:3.40.190.10 189 380 2.4E-16 T 28-03-2018 CNX65_RS08895 0404ec26f45b1defe693ee75ae1219f4 424 Pfam PF13416 Bacterial extracellular solute-binding protein 52 356 5.3E-31 T 28-03-2018 CNX65_RS02290 8a71b855cb17185f544904a10ec4c342 368 Pfam PF13478 XdhC Rossmann domain 201 347 3.6E-42 T 28-03-2018 IPR027051 XdhC Rossmann domain CNX65_RS02290 8a71b855cb17185f544904a10ec4c342 368 Pfam PF02625 XdhC and CoxI family 13 78 4.7E-16 T 28-03-2018 IPR003777 XdhC- CoxI CNX65_RS02290 8a71b855cb17185f544904a10ec4c342 368 Pfam PF02625 XdhC and CoxI family 117 178 2.9E-15 T 28-03-2018 IPR003777 XdhC- CoxI CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Pfam PF02779 Transketolase, pyrimidine binding domain 276 434 2.1E-32 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 SMART SM00861 276 439 2.3E-49 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Gene3D G3DSA:3.40.50.970 260 443 2.0E-45 T 28-03-2018 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 ProSitePatterns PS00801 Transketolase signature 1. 35 54 - T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 18 204 1.3E-78 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 205 247 1.5E-9 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Pfam PF02780 Transketolase, C-terminal domain 456 570 7.7E-21 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 SUPERFAMILY SSF52518 18 338 1.48E-66 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 9 579 35.509 T 28-03-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 SUPERFAMILY SSF52922 448 578 3.01E-20 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 ProSitePatterns PS00802 Transketolase signature 2. 382 398 - T 28-03-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Gene3D G3DSA:3.40.50.970 14 259 6.3E-77 T 28-03-2018 CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 SUPERFAMILY SSF52518 320 423 3.22E-5 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS19000 c64dddc1ad8cc41e69a6e7c2ca05911f 583 Gene3D G3DSA:3.40.50.920 448 580 1.7E-26 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS16615 f80aa604b7a363f501433c37e009d7b4 426 Pfam PF13354 Beta-lactamase enzyme family 162 314 9.2E-21 T 28-03-2018 CNX65_RS16615 f80aa604b7a363f501433c37e009d7b4 426 SUPERFAMILY SSF56601 131 269 1.67E-25 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS16615 f80aa604b7a363f501433c37e009d7b4 426 SUPERFAMILY SSF56601 322 412 1.67E-25 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS16615 f80aa604b7a363f501433c37e009d7b4 426 Gene3D G3DSA:3.40.710.10 128 424 2.5E-23 T 28-03-2018 CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 Gene3D G3DSA:3.30.2080.10 628 773 2.5E-51 T 28-03-2018 CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 TIGRFAM TIGR01180 aman2_put: putative alpha-1,2-mannosidase 20 763 5.4E-175 T 28-03-2018 IPR005887 Alpha-1,2-mannosidase, putative CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 823 876 2.1E-7 T 28-03-2018 IPR018905 Alpha-galactosidase, NEW3 domain CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 Gene3D G3DSA:1.20.1050.60 357 452 7.0E-23 T 28-03-2018 CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 Gene3D G3DSA:2.70.98.10 35 334 5.0E-103 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 Gene3D G3DSA:2.60.40.10 789 890 2.5E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 Gene3D G3DSA:1.20.1610.10 454 627 3.2E-51 T 28-03-2018 CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 SUPERFAMILY SSF48208 273 748 4.08E-26 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS09355 cccfe2d89b3eaef67e393c15d7e76d57 1075 Pfam PF07971 Glycosyl hydrolase family 92 250 760 1.1E-150 T 28-03-2018 IPR012939 Glycosyl hydrolase family 92 CNX65_RS07435 5fc61778196213352eff388c2a0e34a0 425 Pfam PF03631 Virulence factor BrkB 36 296 6.4E-41 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS28990 dbe71a867aaa8e6a446cc22930a12cc6 185 TIGRFAM TIGR00496 frr: ribosome recycling factor 10 185 4.4E-63 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CNX65_RS28990 dbe71a867aaa8e6a446cc22930a12cc6 185 Pfam PF01765 Ribosome recycling factor 21 183 6.6E-58 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CNX65_RS28990 dbe71a867aaa8e6a446cc22930a12cc6 185 Gene3D G3DSA:1.10.132.20 74 184 4.4E-35 T 28-03-2018 CNX65_RS28990 dbe71a867aaa8e6a446cc22930a12cc6 185 Gene3D G3DSA:1.10.132.20 2 73 9.7E-11 T 28-03-2018 CNX65_RS28990 dbe71a867aaa8e6a446cc22930a12cc6 185 SUPERFAMILY SSF55194 3 184 1.44E-66 T 28-03-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 CNX65_RS28990 dbe71a867aaa8e6a446cc22930a12cc6 185 Hamap MF_00040 Ribosome-recycling factor [frr]. 3 185 26.553 T 28-03-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 CNX65_RS03345 9aab667081423fcae590aed43ea3c786 433 Pfam PF13406 Transglycosylase SLT domain 190 238 9.4E-9 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CNX65_RS03345 9aab667081423fcae590aed43ea3c786 433 SUPERFAMILY SSF53955 108 274 3.75E-38 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS03345 9aab667081423fcae590aed43ea3c786 433 Gene3D G3DSA:1.10.530.10 112 359 5.4E-30 T 28-03-2018 CNX65_RS16345 47523d299e4662d59b2fb2bd882c677c 204 Gene3D G3DSA:1.10.357.10 6 193 2.8E-33 T 28-03-2018 CNX65_RS16345 47523d299e4662d59b2fb2bd882c677c 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 55 1.5E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16345 47523d299e4662d59b2fb2bd882c677c 204 SUPERFAMILY SSF46689 2 69 7.7E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS02250 da231da787e6834ab24f8672fbb9a834 165 Gene3D G3DSA:2.60.40.1120 70 163 1.3E-4 T 28-03-2018 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Gene3D G3DSA:1.10.730.10 734 871 2.1E-18 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Pfam PF08264 Anticodon-binding domain of tRNA 782 898 1.4E-11 T 28-03-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0000166|GO:0006418 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 63 73 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Pfam PF09334 tRNA synthetases class I (M) 59 165 1.6E-12 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 SUPERFAMILY SSF47323 748 932 8.6E-27 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 212 933 1.6E-219 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 SUPERFAMILY SSF50677 293 485 4.6E-49 T 28-03-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Gene3D G3DSA:3.40.50.620 473 733 1.0E-56 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Gene3D G3DSA:3.40.50.620 13 295 4.4E-62 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 SUPERFAMILY SSF52374 215 293 9.86E-108 T 28-03-2018 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 SUPERFAMILY SSF52374 21 167 9.86E-108 T 28-03-2018 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 SUPERFAMILY SSF52374 486 752 9.86E-108 T 28-03-2018 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 288 474 7.2E-63 T 28-03-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Gene3D G3DSA:3.90.740.10 296 472 5.6E-55 T 28-03-2018 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 622 644 1.2E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 147 164 1.2E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 655 665 1.2E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 282 301 1.2E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 253 266 1.2E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 570 588 1.2E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 PRINTS PR00985 Leucyl-tRNA synthetase signature 220 236 1.2E-54 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS34940 62d26e8d6a128eb5a9ad52576561c766 933 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 16 933 21.342 T 28-03-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 CNX65_RS01895 422148b3364dda2d2ca86c13e9fadb42 78 Gene3D G3DSA:3.40.50.880 9 78 0.0014 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 46 8.5E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 SUPERFAMILY SSF47413 1 58 3.38E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 Gene3D G3DSA:3.40.50.2300 160 286 2.0E-19 T 28-03-2018 CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 Pfam PF13377 Periplasmic binding protein-like domain 154 305 3.6E-16 T 28-03-2018 CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 Gene3D G3DSA:1.10.260.40 2 55 1.8E-17 T 28-03-2018 CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 SMART SM00354 1 71 2.2E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 SUPERFAMILY SSF53822 72 287 2.55E-31 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS25430 98b5dd6f8a5c75be93b3bf3c74726637 320 Gene3D G3DSA:3.40.50.2300 56 159 1.1E-16 T 28-03-2018 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 SUPERFAMILY SSF53098 15 231 6.91E-55 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 SMART SM00474 27 194 4.8E-39 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 Pfam PF01612 3'-5' exonuclease 30 193 5.3E-34 T 28-03-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 Gene3D G3DSA:3.30.420.10 15 216 2.7E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 SUPERFAMILY SSF47819 215 324 4.8E-25 T 28-03-2018 IPR010997 HRDC-like GO:0000166|GO:0003824|GO:0044237 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 Pfam PF00570 HRDC domain 236 302 3.1E-13 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 Gene3D G3DSA:1.10.150.80 217 337 4.4E-30 T 28-03-2018 CNX65_RS07680 3aaada0b02e6857b59ce5c7cedfd6890 414 SMART SM00341 233 313 3.5E-13 T 28-03-2018 IPR002121 HRDC domain GO:0003676|GO:0005622 CNX65_RS21160 80aa431eae31d411eeee4c07a1651b74 536 Pfam PF01740 STAS domain 429 510 9.4E-12 T 28-03-2018 IPR002645 STAS domain CNX65_RS21160 80aa431eae31d411eeee4c07a1651b74 536 Pfam PF00916 Sulfate permease family 17 375 1.1E-66 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CNX65_RS21160 80aa431eae31d411eeee4c07a1651b74 536 Gene3D G3DSA:3.30.750.24 425 528 1.4E-17 T 28-03-2018 IPR002645 STAS domain CNX65_RS21160 80aa431eae31d411eeee4c07a1651b74 536 SUPERFAMILY SSF52091 428 524 9.42E-15 T 28-03-2018 IPR002645 STAS domain CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 7.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 7.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 7.2E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 SUPERFAMILY SSF52172 3 135 1.99E-29 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 Pfam PF00072 Response regulator receiver domain 5 117 1.8E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 SMART SM00448 3 117 8.7E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 210 4.5E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 SUPERFAMILY SSF46894 138 215 5.78E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 SMART SM00421 153 210 1.6E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 Gene3D G3DSA:1.10.10.10 129 216 1.4E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32015 8f7d9ac77ff87866200f79f47e9608f5 216 Gene3D G3DSA:3.40.50.2300 2 128 3.6E-31 T 28-03-2018 CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 SUPERFAMILY SSF141868 6 231 6.41E-43 T 28-03-2018 IPR001633 EAL domain CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 SMART SM00267 384 546 2.4E-5 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 SUPERFAMILY SSF54631 267 403 6.59E-7 T 28-03-2018 CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 SUPERFAMILY SSF55073 400 480 6.59E-12 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 SMART SM00052 6 229 2.3E-13 T 28-03-2018 IPR001633 EAL domain CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 Gene3D G3DSA:3.30.70.270 394 489 3.1E-18 T 28-03-2018 CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 Pfam PF00990 Diguanylate cyclase, GGDEF domain 398 479 2.5E-8 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 Gene3D G3DSA:3.10.580.10 245 393 8.6E-8 T 28-03-2018 CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 Pfam PF00563 EAL domain 7 223 4.8E-39 T 28-03-2018 IPR001633 EAL domain CNX65_RS25590 b556d86672e1c8bb2d1c6109d11299f7 565 Gene3D G3DSA:3.20.20.450 4 238 6.9E-43 T 28-03-2018 IPR001633 EAL domain CNX65_RS11220 1b08ce5c3c94ed1b345bd75d7c749c48 150 Gene3D G3DSA:1.10.10.10 1 82 2.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11220 1b08ce5c3c94ed1b345bd75d7c749c48 150 Pfam PF12802 MarR family 16 75 1.7E-7 T 28-03-2018 CNX65_RS11220 1b08ce5c3c94ed1b345bd75d7c749c48 150 SUPERFAMILY SSF46785 3 103 1.42E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10010 78aaf99d01b89c7fabbac8a13a74b654 521 Pfam PF01274 Malate synthase 10 514 8.0E-178 T 28-03-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS10010 78aaf99d01b89c7fabbac8a13a74b654 521 TIGRFAM TIGR01344 malate_syn_A: malate synthase A 20 513 1.0E-216 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS10010 78aaf99d01b89c7fabbac8a13a74b654 521 Gene3D G3DSA:3.20.20.360 80 404 2.8E-104 T 28-03-2018 CNX65_RS10010 78aaf99d01b89c7fabbac8a13a74b654 521 SUPERFAMILY SSF51645 6 516 4.05E-167 T 28-03-2018 IPR011076 Malate synthase-like GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS10010 78aaf99d01b89c7fabbac8a13a74b654 521 ProSitePatterns PS00510 Malate synthase signature. 263 278 - T 28-03-2018 IPR019830 Malate synthase, conserved site GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS10010 78aaf99d01b89c7fabbac8a13a74b654 521 Gene3D G3DSA:1.20.1220.12 405 518 4.1E-33 T 28-03-2018 CNX65_RS10010 78aaf99d01b89c7fabbac8a13a74b654 521 PIRSF PIRSF001363 1 518 4.0E-218 T 28-03-2018 IPR006252 Malate synthase A GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 CNX65_RS25760 f2617b76e454313ef3483d21f940ba1e 195 Gene3D G3DSA:3.10.50.40 34 195 1.5E-30 T 28-03-2018 CNX65_RS25760 f2617b76e454313ef3483d21f940ba1e 195 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 102 190 3.5E-19 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CNX65_RS25760 f2617b76e454313ef3483d21f940ba1e 195 SUPERFAMILY SSF54534 65 195 6.29E-30 T 28-03-2018 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 14 31 4.4E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 169 192 4.4E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 208 227 4.4E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 234 253 4.4E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 86 103 4.4E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR01397 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature 106 126 4.4E-51 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 187 0.0019 T 28-03-2018 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 TIGRFAM TIGR04316 dhbA_paeA: 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase 10 257 1.7E-94 T 28-03-2018 IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase GO:0008667|GO:0019290|GO:0055114 MetaCyc: PWY-5901 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 2.0E-59 T 28-03-2018 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 SUPERFAMILY SSF51735 6 254 4.3E-74 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 Gene3D G3DSA:3.40.50.720 1 257 8.8E-71 T 28-03-2018 CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 83 94 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15945 09848e47c335cb8b149cb08a3cb636d7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 1.8E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19565 3f05337c90ba600f8073d01544dbdf52 437 Pfam PF01266 FAD dependent oxidoreductase 26 379 6.0E-46 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS19565 3f05337c90ba600f8073d01544dbdf52 437 SUPERFAMILY SSF51905 341 397 1.42E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19565 3f05337c90ba600f8073d01544dbdf52 437 SUPERFAMILY SSF51905 25 233 1.42E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19565 3f05337c90ba600f8073d01544dbdf52 437 Gene3D G3DSA:3.30.9.10 218 332 1.4E-11 T 28-03-2018 CNX65_RS19565 3f05337c90ba600f8073d01544dbdf52 437 Gene3D G3DSA:3.50.50.60 333 399 5.4E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19565 3f05337c90ba600f8073d01544dbdf52 437 Gene3D G3DSA:3.50.50.60 20 126 6.9E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19565 3f05337c90ba600f8073d01544dbdf52 437 Gene3D G3DSA:3.50.50.60 127 217 6.3E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15930 0d3adb345c8888c11c3c71e28d6eb1eb 146 SUPERFAMILY SSF54593 2 135 7.33E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS15930 0d3adb345c8888c11c3c71e28d6eb1eb 146 Gene3D G3DSA:3.10.180.10 1 141 4.2E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS15930 0d3adb345c8888c11c3c71e28d6eb1eb 146 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 106 7.1E-16 T 28-03-2018 CNX65_RS23385 ce1317b072cb06700e00255ed99758fd 135 Pfam PF12680 SnoaL-like domain 22 123 6.9E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS23385 ce1317b072cb06700e00255ed99758fd 135 SUPERFAMILY SSF54427 16 131 5.16E-25 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS23385 ce1317b072cb06700e00255ed99758fd 135 Gene3D G3DSA:3.10.450.50 10 125 1.6E-16 T 28-03-2018 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 PIRSF PIRSF001563 13 451 2.4E-115 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 Gene3D G3DSA:3.40.1190.10 7 307 2.9E-82 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 Pfam PF02875 Mur ligase family, glutamate ligase domain 307 385 1.5E-11 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 Pfam PF08245 Mur ligase middle domain 53 280 1.9E-13 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 Gene3D G3DSA:3.90.190.20 308 452 1.2E-29 T 28-03-2018 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 SUPERFAMILY SSF53623 17 304 2.04E-90 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 SUPERFAMILY SSF53244 308 449 3.11E-27 T 28-03-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 CNX65_RS05810 67d33b1a579a33f984886a275d7f6229 452 TIGRFAM TIGR01499 folC: bifunctional protein FolC 31 445 4.0E-102 T 28-03-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 CNX65_RS17260 bffc73b48539ebd9f8447d75fb6bc5a7 318 Pfam PF13556 PucR C-terminal helix-turn-helix domain 254 310 4.8E-13 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS24630 14d203891a6815b28165705f1474cc1f 538 Gene3D G3DSA:1.20.200.10 209 535 1.4E-108 T 28-03-2018 CNX65_RS24630 14d203891a6815b28165705f1474cc1f 538 Gene3D G3DSA:1.10.275.10 5 207 1.2E-63 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CNX65_RS24630 14d203891a6815b28165705f1474cc1f 538 Pfam PF00221 Aromatic amino acid lyase 21 499 8.0E-163 T 28-03-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 CNX65_RS24630 14d203891a6815b28165705f1474cc1f 538 SUPERFAMILY SSF48557 9 527 2.67E-169 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CNX65_RS24630 14d203891a6815b28165705f1474cc1f 538 TIGRFAM TIGR03832 Tyr_2_3_mutase: tyrosine 2,3-aminomutase 16 521 4.0E-276 T 28-03-2018 IPR022314 Tyrosine 2,3-aminomutase, putative KEGG: 00350+5.4.3.6+4.3.1.23 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 Gene3D G3DSA:3.40.47.10 281 402 2.1E-32 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 Gene3D G3DSA:3.40.47.10 1 280 3.5E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 SUPERFAMILY SSF53901 283 404 2.66E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 SUPERFAMILY SSF53901 3 282 5.26E-66 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 Pfam PF02803 Thiolase, C-terminal domain 283 404 2.7E-47 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 403 3.7E-134 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 PIRSF PIRSF000429 1 406 2.8E-125 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 Pfam PF00108 Thiolase, N-terminal domain 5 273 2.4E-57 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CNX65_RS03480 14671c04f533c47ac3cab5df41755f89 406 ProSitePatterns PS00737 Thiolases signature 2. 351 367 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CNX65_RS27180 e624c7cce2f4bf29d6da2b4a1dafd52c 390 SUPERFAMILY SSF56266 10 386 2.75E-125 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS27180 e624c7cce2f4bf29d6da2b4a1dafd52c 390 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 390 133.631 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS27180 e624c7cce2f4bf29d6da2b4a1dafd52c 390 Gene3D G3DSA:3.60.70.12 2 266 2.6E-94 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS27180 e624c7cce2f4bf29d6da2b4a1dafd52c 390 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 5 389 3.2E-112 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS27180 e624c7cce2f4bf29d6da2b4a1dafd52c 390 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 21 388 1.0E-116 T 28-03-2018 CNX65_RS27180 e624c7cce2f4bf29d6da2b4a1dafd52c 390 Pfam PF01960 ArgJ family 15 390 1.2E-129 T 28-03-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS25960 eee864373cb13397edb956deeb3bfdd4 160 Gene3D G3DSA:3.40.50.960 2 157 1.0E-54 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25960 eee864373cb13397edb956deeb3bfdd4 160 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 12 155 26.24 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25960 eee864373cb13397edb956deeb3bfdd4 160 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 19 150 1.5E-41 T 28-03-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25960 eee864373cb13397edb956deeb3bfdd4 160 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 17 151 1.9E-47 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS25960 eee864373cb13397edb956deeb3bfdd4 160 SUPERFAMILY SSF52121 11 155 9.29E-49 T 28-03-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 SMART SM00450 148 266 9.7E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 SMART SM00450 3 127 1.6E-21 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 SUPERFAMILY SSF52821 2 142 3.01E-38 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 Gene3D G3DSA:3.40.250.10 2 145 1.6E-29 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 Gene3D G3DSA:3.40.250.10 146 272 1.5E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 Pfam PF00581 Rhodanese-like domain 6 122 9.0E-16 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 Pfam PF00581 Rhodanese-like domain 163 262 9.9E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 ProSitePatterns PS00380 Rhodanese signature 1. 35 46 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CNX65_RS21560 34c8329a4e171e76e44e030919b54a29 272 SUPERFAMILY SSF52821 148 271 9.17E-34 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS06975 fb688640fe355a5dc71e4e202f9d0b13 278 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 19 159 8.0E-6 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS06975 fb688640fe355a5dc71e4e202f9d0b13 278 Pfam PF07398 MDMPI C-terminal domain 173 267 1.0E-7 T 28-03-2018 IPR010872 MDMPI C-terminal CNX65_RS06975 fb688640fe355a5dc71e4e202f9d0b13 278 Gene3D G3DSA:1.20.120.450 8 163 3.1E-6 T 28-03-2018 CNX65_RS10805 88269d1aca7780819e14c3fc7be68522 198 Gene3D G3DSA:1.10.357.10 2 195 8.2E-31 T 28-03-2018 CNX65_RS10805 88269d1aca7780819e14c3fc7be68522 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS10805 88269d1aca7780819e14c3fc7be68522 198 SUPERFAMILY SSF46689 3 74 1.28E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS10805 88269d1aca7780819e14c3fc7be68522 198 SUPERFAMILY SSF48498 100 194 3.26E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS10805 88269d1aca7780819e14c3fc7be68522 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 9.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10805 88269d1aca7780819e14c3fc7be68522 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 9.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10805 88269d1aca7780819e14c3fc7be68522 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 7.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21165 62070bfb50affd3ada1b57d971a76f8c 258 Gene3D G3DSA:1.10.1660.10 57 141 3.4E-5 T 28-03-2018 CNX65_RS21165 62070bfb50affd3ada1b57d971a76f8c 258 SUPERFAMILY SSF46955 4 101 1.36E-17 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS21165 62070bfb50affd3ada1b57d971a76f8c 258 Pfam PF00376 MerR family regulatory protein 4 41 2.6E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS21165 62070bfb50affd3ada1b57d971a76f8c 258 Gene3D G3DSA:1.10.1660.10 1 56 5.4E-16 T 28-03-2018 CNX65_RS21165 62070bfb50affd3ada1b57d971a76f8c 258 SMART SM00422 3 72 1.9E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS10860 ec03b144ea2e18567a0b235e7df4d25f 309 SUPERFAMILY SSF55874 216 308 2.61E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10860 ec03b144ea2e18567a0b235e7df4d25f 309 Gene3D G3DSA:3.30.565.10 180 309 9.5E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10860 ec03b144ea2e18567a0b235e7df4d25f 309 Pfam PF07730 Histidine kinase 150 211 1.4E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 SUPERFAMILY SSF46894 142 215 1.12E-19 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 SMART SM00448 2 115 1.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 SUPERFAMILY SSF52172 2 130 8.97E-32 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 Pfam PF00072 Response regulator receiver domain 4 113 5.8E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.6E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 SMART SM00421 152 209 1.2E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 Gene3D G3DSA:1.10.10.10 134 214 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 Gene3D G3DSA:3.40.50.2300 1 133 4.7E-36 T 28-03-2018 CNX65_RS18510 713c39ec6dab24a5bce6172b132ad560 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 1.9E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 SUPERFAMILY SSF47413 5 64 1.97E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 Gene3D G3DSA:1.10.260.40 6 58 7.5E-19 T 28-03-2018 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 SUPERFAMILY SSF53822 67 340 4.56E-68 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 Pfam PF13377 Periplasmic binding protein-like domain 180 337 5.9E-36 T 28-03-2018 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 Gene3D G3DSA:3.40.50.2300 186 319 3.5E-47 T 28-03-2018 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 SMART SM00354 5 76 1.7E-25 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 ProSitePatterns PS00356 LacI-type HTH domain signature. 8 26 - T 28-03-2018 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 Gene3D G3DSA:3.40.50.2300 59 185 5.1E-30 T 28-03-2018 CNX65_RS26600 d7fdd4f680795538cda10cab22f625d7 346 Pfam PF00356 Bacterial regulatory proteins, lacI family 7 53 1.6E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS03860 bf9ec8aa39a7723535c19122c0b3c04d 239 Pfam PF13305 WHG domain 109 192 1.4E-10 T 28-03-2018 IPR025996 WHG domain CNX65_RS03860 bf9ec8aa39a7723535c19122c0b3c04d 239 Gene3D G3DSA:1.10.357.10 90 219 1.3E-20 T 28-03-2018 CNX65_RS03860 bf9ec8aa39a7723535c19122c0b3c04d 239 Gene3D G3DSA:1.10.10.60 70 89 9.7E-6 T 28-03-2018 CNX65_RS03860 bf9ec8aa39a7723535c19122c0b3c04d 239 Gene3D G3DSA:1.10.10.60 4 69 7.3E-15 T 28-03-2018 CNX65_RS03860 bf9ec8aa39a7723535c19122c0b3c04d 239 SUPERFAMILY SSF46689 20 107 9.98E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS03860 bf9ec8aa39a7723535c19122c0b3c04d 239 SUPERFAMILY SSF48498 105 203 1.7E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS03860 bf9ec8aa39a7723535c19122c0b3c04d 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 73 6.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS32020 4ea832155bcecdf8555cc2724b4fb9f1 444 Pfam PF04024 PspC domain 52 105 8.3E-14 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CNX65_RS32020 4ea832155bcecdf8555cc2724b4fb9f1 444 SUPERFAMILY SSF55874 343 438 8.08E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS32020 4ea832155bcecdf8555cc2724b4fb9f1 444 Gene3D G3DSA:3.30.565.10 307 444 4.5E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS35060 aece9bf90916ae6a4f14d71b50d9cf6c 183 Gene3D G3DSA:3.30.1370.50 114 183 1.3E-18 T 28-03-2018 IPR001374 R3H domain GO:0003676 CNX65_RS35060 aece9bf90916ae6a4f14d71b50d9cf6c 183 SMART SM00393 103 182 5.7E-23 T 28-03-2018 IPR001374 R3H domain GO:0003676 CNX65_RS35060 aece9bf90916ae6a4f14d71b50d9cf6c 183 Pfam PF01424 R3H domain 124 179 3.6E-14 T 28-03-2018 IPR001374 R3H domain GO:0003676 CNX65_RS35060 aece9bf90916ae6a4f14d71b50d9cf6c 183 Gene3D G3DSA:3.30.300.20 34 112 2.6E-17 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS35060 aece9bf90916ae6a4f14d71b50d9cf6c 183 SUPERFAMILY SSF82708 136 181 1.73E-10 T 28-03-2018 IPR001374 R3H domain GO:0003676 CNX65_RS23905 6dab868d06c7e9c87a4d62136b7c7461 202 SUPERFAMILY SSF52540 22 195 1.18E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23905 6dab868d06c7e9c87a4d62136b7c7461 202 PRINTS PR00449 Transforming protein P21 ras signature 23 44 8.1E-5 T 28-03-2018 CNX65_RS23905 6dab868d06c7e9c87a4d62136b7c7461 202 PRINTS PR00449 Transforming protein P21 ras signature 170 192 8.1E-5 T 28-03-2018 CNX65_RS23905 6dab868d06c7e9c87a4d62136b7c7461 202 Pfam PF03029 Conserved hypothetical ATP binding protein 27 193 3.7E-25 T 28-03-2018 IPR004130 GPN-loop GTPase CNX65_RS23905 6dab868d06c7e9c87a4d62136b7c7461 202 Gene3D G3DSA:3.40.50.300 17 196 1.2E-16 T 28-03-2018 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 Gene3D G3DSA:3.20.20.70 69 359 5.6E-90 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 Pfam PF16499 Alpha galactosidase A 77 361 1.9E-75 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 SUPERFAMILY SSF51445 68 362 3.86E-81 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 Gene3D G3DSA:2.80.10.50 461 579 9.7E-27 T 28-03-2018 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 SUPERFAMILY SSF51011 354 448 6.65E-14 T 28-03-2018 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 SUPERFAMILY SSF50370 455 578 9.47E-30 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 SMART SM00458 454 579 2.0E-16 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 Gene3D G3DSA:2.60.40.1180 360 460 3.4E-22 T 28-03-2018 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 PRINTS PR00740 Glycosyl hydrolase family 27 signature 72 91 3.4E-48 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 PRINTS PR00740 Glycosyl hydrolase family 27 signature 190 207 3.4E-48 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 PRINTS PR00740 Glycosyl hydrolase family 27 signature 108 123 3.4E-48 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 PRINTS PR00740 Glycosyl hydrolase family 27 signature 219 237 3.4E-48 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 PRINTS PR00740 Glycosyl hydrolase family 27 signature 296 315 3.4E-48 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 PRINTS PR00740 Glycosyl hydrolase family 27 signature 317 338 3.4E-48 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS18975 e77baca5e549ec7f69b14350c4b9b41e 579 Pfam PF00652 Ricin-type beta-trefoil lectin domain 456 576 2.3E-21 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 Gene3D G3DSA:3.30.540.10 8 143 1.1E-12 T 28-03-2018 CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 Pfam PF00459 Inositol monophosphatase family 20 261 2.5E-13 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 88 104 2.8E-7 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 48 68 2.8E-7 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 173 194 2.8E-7 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 2.8E-7 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 SUPERFAMILY SSF56655 12 261 7.85E-33 T 28-03-2018 CNX65_RS31850 385dfb755fdcd4f92078ef1392d5e882 264 Gene3D G3DSA:3.40.190.80 144 263 2.8E-15 T 28-03-2018 CNX65_RS06200 e57c3fdb1db960788e5f38fa66bf3a58 404 SUPERFAMILY SSF52266 203 403 2.14E-43 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS06200 e57c3fdb1db960788e5f38fa66bf3a58 404 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 208 393 3.3E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS06200 e57c3fdb1db960788e5f38fa66bf3a58 404 Gene3D G3DSA:3.40.50.1110 196 401 1.1E-26 T 28-03-2018 CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 SMART SM00052 491 728 1.2E-10 T 28-03-2018 IPR001633 EAL domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 Pfam PF00989 PAS fold 202 305 4.5E-8 T 28-03-2018 IPR013767 PAS fold GO:0006355 CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 Gene3D G3DSA:3.30.70.270 319 488 2.0E-43 T 28-03-2018 CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 SUPERFAMILY SSF55785 201 305 3.32E-14 T 28-03-2018 IPR000014 PAS domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 Pfam PF00990 Diguanylate cyclase, GGDEF domain 321 474 5.9E-30 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 Gene3D G3DSA:3.20.20.450 489 728 6.8E-44 T 28-03-2018 IPR001633 EAL domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 SMART SM00267 309 481 6.3E-37 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 Gene3D G3DSA:3.30.450.20 199 318 1.5E-16 T 28-03-2018 CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 SUPERFAMILY SSF55073 325 483 1.33E-32 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 316 477 4.3E-27 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 SUPERFAMILY SSF141868 501 726 6.93E-29 T 28-03-2018 IPR001633 EAL domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 204 309 1.4E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS11635 f986865a0f18f5b6e55802d760e69f0c 729 Pfam PF00563 EAL domain 502 724 7.8E-30 T 28-03-2018 IPR001633 EAL domain CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 82 103 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 Pfam PF13602 Zinc-binding dehydrogenase 125 255 1.1E-18 T 28-03-2018 CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 Gene3D G3DSA:3.90.180.10 2 81 5.2E-12 T 28-03-2018 CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 SUPERFAMILY SSF51735 60 229 4.62E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 SMART SM00829 5 255 8.3E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 Gene3D G3DSA:3.90.180.10 188 258 0.21 T 28-03-2018 CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 Gene3D G3DSA:3.40.50.720 82 187 5.6E-25 T 28-03-2018 CNX65_RS17380 dcdb65c4bb36db0c369d98d609fd31d8 258 SUPERFAMILY SSF50129 2 87 7.54E-11 T 28-03-2018 IPR011032 GroES-like CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 155 208 1.9E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 SUPERFAMILY SSF46894 149 215 2.21E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 SMART SM00421 153 210 2.0E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 Gene3D G3DSA:1.10.10.10 137 215 6.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 SMART SM00448 3 118 2.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 Pfam PF00072 Response regulator receiver domain 5 118 8.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 170 197 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 SUPERFAMILY SSF52172 3 136 1.05E-29 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 156 170 6.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 186 198 6.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 170 186 6.0E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20025 24477c6bcbbebf74032829292c5ec185 217 Gene3D G3DSA:3.40.50.2300 2 136 5.4E-34 T 28-03-2018 CNX65_RS33875 ca56d7dfc2cb98029abcbd9845ceb5f1 338 SUPERFAMILY SSF51735 2 146 4.3E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS33875 ca56d7dfc2cb98029abcbd9845ceb5f1 338 Gene3D G3DSA:3.30.360.10 130 333 1.3E-41 T 28-03-2018 CNX65_RS33875 ca56d7dfc2cb98029abcbd9845ceb5f1 338 SUPERFAMILY SSF55347 123 286 7.19E-26 T 28-03-2018 CNX65_RS33875 ca56d7dfc2cb98029abcbd9845ceb5f1 338 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 133 237 5.1E-7 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS33875 ca56d7dfc2cb98029abcbd9845ceb5f1 338 Gene3D G3DSA:3.40.50.720 1 129 5.1E-31 T 28-03-2018 CNX65_RS33875 ca56d7dfc2cb98029abcbd9845ceb5f1 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 118 9.9E-17 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 Pfam PF00271 Helicase conserved C-terminal domain 354 433 2.0E-4 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 SMART SM00490 343 433 4.1E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 Gene3D G3DSA:3.40.50.300 4 207 5.0E-37 T 28-03-2018 CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 SMART SM00487 31 213 2.0E-32 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 Gene3D G3DSA:3.40.50.300 263 573 2.4E-17 T 28-03-2018 CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 SUPERFAMILY SSF52540 353 446 4.57E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 SUPERFAMILY SSF52540 45 186 4.57E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 SUPERFAMILY SSF52540 254 311 4.57E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 SMART SM01142 802 977 1.0E-66 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 Pfam PF00270 DEAD/DEAH box helicase 37 184 3.1E-18 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS11475 b5156737510beb3542b578b5abedbc6c 978 Pfam PF08148 DSHCT (NUC185) domain 806 973 4.2E-39 T 28-03-2018 IPR012961 ATP-dependent RNA helicase Ski2, C-terminal CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 Gene3D G3DSA:1.10.1660.10 1 58 1.4E-16 T 28-03-2018 CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 Pfam PF13411 MerR HTH family regulatory protein 5 70 1.2E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 4.1E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 4.1E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 4.1E-5 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 SUPERFAMILY SSF46955 4 75 1.28E-14 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 SMART SM00422 4 72 4.6E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28435 5ca8b7767d1ac09cdcf434489299a763 284 Gene3D G3DSA:1.10.1660.10 59 121 2.7E-4 T 28-03-2018 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 SUPERFAMILY SSF50494 199 370 2.84E-33 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 Gene3D G3DSA:2.40.10.10 193 273 7.0E-19 T 28-03-2018 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 Gene3D G3DSA:2.40.10.10 274 363 4.3E-17 T 28-03-2018 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 317 340 1.4E-38 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 216 230 1.4E-38 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 298 315 1.4E-38 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 341 355 1.4E-38 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 277 297 1.4E-38 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 Gene3D G3DSA:3.30.300.50 34 117 2.2E-20 T 28-03-2018 IPR035070 Streptogrisin prodomain CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 Gene3D G3DSA:3.30.300.50 118 183 6.2E-11 T 28-03-2018 IPR035070 Streptogrisin prodomain CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 Pfam PF02983 Alpha-lytic protease prodomain 121 172 2.4E-9 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 PIRSF PIRSF001134 3 378 5.4E-118 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS22460 54ff4ff602196483b19efae8af43a806 378 Pfam PF00089 Trypsin 249 368 4.7E-10 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS09160 5968b39e6a3f48bd14aee3098af65465 290 SUPERFAMILY SSF47413 68 127 6.76E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09160 5968b39e6a3f48bd14aee3098af65465 290 Gene3D G3DSA:1.10.260.40 63 252 7.8E-9 T 28-03-2018 CNX65_RS09160 5968b39e6a3f48bd14aee3098af65465 290 SMART SM00530 74 129 8.6E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS09160 5968b39e6a3f48bd14aee3098af65465 290 Pfam PF13560 Helix-turn-helix domain 70 128 4.2E-12 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Gene3D G3DSA:3.40.50.980 245 418 1.6E-24 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1196 1211 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 SUPERFAMILY SSF51735 848 1078 4.55E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Pfam PF08659 KR domain 851 1038 7.5E-32 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Gene3D G3DSA:2.30.38.10 447 520 7.5E-21 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Pfam PF00550 Phosphopantetheine attachment site 1178 1237 9.9E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 SMART SM00823 Phosphopantetheine attachment site 1172 1241 5.1E-5 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Gene3D G3DSA:3.40.50.720 843 1097 1.0E-36 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 851 1039 4.9E-14 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Gene3D G3DSA:1.10.1200.10 1153 1240 7.2E-23 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 SUPERFAMILY SSF47336 1165 1237 1.83E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Pfam PF00501 AMP-binding enzyme 97 527 2.8E-55 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Gene3D G3DSA:3.30.300.30 521 648 8.0E-16 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 Gene3D G3DSA:3.40.50.980 74 244 8.7E-25 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 SUPERFAMILY SSF56801 66 414 7.2E-94 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 SUPERFAMILY SSF56801 446 630 7.2E-94 T 28-03-2018 CNX65_RS17025 b9b928812e3262f5438884141d99a3d3 1241 SUPERFAMILY SSF51735 645 837 2.6E-14 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS05965 f6f2d47798525a79a150b77fdd98d953 197 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 70 2.6E-10 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CNX65_RS05965 f6f2d47798525a79a150b77fdd98d953 197 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 8 193 5.9E-54 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CNX65_RS05965 f6f2d47798525a79a150b77fdd98d953 197 SUPERFAMILY SSF52374 4 195 4.38E-54 T 28-03-2018 CNX65_RS05965 f6f2d47798525a79a150b77fdd98d953 197 Pfam PF01467 Cytidylyltransferase-like 8 168 4.3E-29 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CNX65_RS05965 f6f2d47798525a79a150b77fdd98d953 197 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 4 194 30.077 T 28-03-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 CNX65_RS05965 f6f2d47798525a79a150b77fdd98d953 197 Gene3D G3DSA:3.40.50.620 1 195 3.9E-52 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 SUPERFAMILY SSF46785 7 71 1.32E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 SUPERFAMILY SSF100950 77 235 1.57E-23 T 28-03-2018 CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 SMART SM00420 9 61 1.5E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 SMART SM01134 75 235 6.3E-57 T 28-03-2018 CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 Pfam PF08220 DeoR-like helix-turn-helix domain 9 60 1.1E-12 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 Gene3D G3DSA:1.10.10.10 4 76 4.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 ProSitePatterns PS00894 DeoR-type HTH domain signature. 9 43 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 Pfam PF00455 DeoR C terminal sensor domain 77 233 2.2E-41 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 27 41 4.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 41 59 4.0E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS25490 2c612f6a607e6af3da49f75c4586c6a7 254 Gene3D G3DSA:3.40.50.1360 77 242 2.9E-31 T 28-03-2018 CNX65_RS17590 ed335be9191d8ac8991c651304b6963c 293 Gene3D G3DSA:1.10.3720.10 7 278 1.2E-38 T 28-03-2018 CNX65_RS17590 ed335be9191d8ac8991c651304b6963c 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 289 1.9E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17590 ed335be9191d8ac8991c651304b6963c 293 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 16 65 7.2E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CNX65_RS17590 ed335be9191d8ac8991c651304b6963c 293 SUPERFAMILY SSF161098 84 272 3.27E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17970 92d0b7543cbdd1134bda41224c9c3087 399 Pfam PF07690 Major Facilitator Superfamily 22 247 1.5E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS17970 92d0b7543cbdd1134bda41224c9c3087 399 Gene3D G3DSA:1.20.1250.20 207 399 2.4E-15 T 28-03-2018 CNX65_RS17970 92d0b7543cbdd1134bda41224c9c3087 399 Gene3D G3DSA:1.20.1250.20 17 201 2.9E-21 T 28-03-2018 CNX65_RS17970 92d0b7543cbdd1134bda41224c9c3087 399 SUPERFAMILY SSF103473 16 388 4.84E-48 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS18670 92f5304788b26fd33dcfa4fe605597bc 450 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 60 129 2.8E-5 T 28-03-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 CNX65_RS18670 92f5304788b26fd33dcfa4fe605597bc 450 Gene3D G3DSA:3.40.50.720 7 155 7.2E-14 T 28-03-2018 CNX65_RS18670 92f5304788b26fd33dcfa4fe605597bc 450 SMART SM00858 345 413 4.5E-4 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CNX65_RS18670 92f5304788b26fd33dcfa4fe605597bc 450 SUPERFAMILY SSF51735 12 131 2.9E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18670 92f5304788b26fd33dcfa4fe605597bc 450 Gene3D G3DSA:3.90.1210.10 347 417 0.049 T 28-03-2018 CNX65_RS30295 cb59d5736fde60e15feda3187407bae6 358 PIRSF PIRSF038945 2 357 1.6E-162 T 28-03-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 CNX65_RS30295 cb59d5736fde60e15feda3187407bae6 358 TIGRFAM TIGR00260 thrC: threonine synthase 18 332 2.1E-89 T 28-03-2018 IPR004450 Threonine synthase-like CNX65_RS30295 cb59d5736fde60e15feda3187407bae6 358 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 31 325 2.2E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS30295 cb59d5736fde60e15feda3187407bae6 358 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 59 72 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CNX65_RS30295 cb59d5736fde60e15feda3187407bae6 358 Gene3D G3DSA:3.40.50.1100 153 341 6.8E-49 T 28-03-2018 CNX65_RS30295 cb59d5736fde60e15feda3187407bae6 358 SUPERFAMILY SSF53686 12 341 3.8E-99 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS30295 cb59d5736fde60e15feda3187407bae6 358 Gene3D G3DSA:3.40.50.1100 46 152 4.2E-26 T 28-03-2018 CNX65_RS30450 c50e91aef28fcf61813a7e7608b978a5 284 Pfam PF00005 ABC transporter 28 171 8.5E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS30450 c50e91aef28fcf61813a7e7608b978a5 284 Gene3D G3DSA:3.40.50.300 1 280 1.1E-63 T 28-03-2018 CNX65_RS30450 c50e91aef28fcf61813a7e7608b978a5 284 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS30450 c50e91aef28fcf61813a7e7608b978a5 284 SMART SM00382 36 221 1.1E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30450 c50e91aef28fcf61813a7e7608b978a5 284 SUPERFAMILY SSF52540 11 242 1.52E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30450 c50e91aef28fcf61813a7e7608b978a5 284 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 223 256 1.1E-7 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 169 188 1.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 1.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 203 216 1.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 91 105 1.4E-21 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 371 448 1.7E-15 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 SUPERFAMILY SSF53738 151 254 2.83E-29 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 259 366 2.3E-25 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 SUPERFAMILY SSF53738 7 121 1.77E-31 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 131 1.3E-30 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 153 252 1.3E-24 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 SUPERFAMILY SSF55957 366 450 7.72E-18 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Gene3D G3DSA:3.40.120.10 7 156 5.3E-32 T 28-03-2018 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Gene3D G3DSA:3.40.120.10 157 262 1.2E-34 T 28-03-2018 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Gene3D G3DSA:3.40.120.10 263 362 5.0E-28 T 28-03-2018 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 SUPERFAMILY SSF53738 258 362 9.03E-30 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31130 fe9d2819785e5276d59bb78508b6cabc 450 Gene3D G3DSA:3.30.310.50 363 450 2.6E-20 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS17410 bf18dcef5d0a896b0bcc75b157e6de81 174 Gene3D G3DSA:1.10.3300.10 8 171 2.2E-30 T 28-03-2018 IPR023286 ABATE domain CNX65_RS17410 bf18dcef5d0a896b0bcc75b157e6de81 174 Pfam PF11706 CGNR zinc finger 127 169 2.1E-16 T 28-03-2018 IPR021005 Zinc finger, CGNR CNX65_RS17410 bf18dcef5d0a896b0bcc75b157e6de81 174 SUPERFAMILY SSF160904 2 168 9.55E-35 T 28-03-2018 CNX65_RS12330 c640be750c2e195ff000dd941891d904 267 Gene3D G3DSA:3.40.50.1820 2 267 8.1E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS12330 c640be750c2e195ff000dd941891d904 267 PRINTS PR00412 Epoxide hydrolase signature 106 119 9.2E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS12330 c640be750c2e195ff000dd941891d904 267 PRINTS PR00412 Epoxide hydrolase signature 241 263 9.2E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS12330 c640be750c2e195ff000dd941891d904 267 PRINTS PR00412 Epoxide hydrolase signature 47 62 9.2E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS12330 c640be750c2e195ff000dd941891d904 267 SUPERFAMILY SSF53474 1 266 1.57E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS12330 c640be750c2e195ff000dd941891d904 267 Pfam PF12697 Alpha/beta hydrolase family 23 258 2.6E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 Pfam PF09992 Phosphodiester glycosidase 240 410 5.3E-34 T 28-03-2018 IPR018711 Phosphodiester glycosidase CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 Gene3D G3DSA:3.60.21.10 779 1029 5.8E-29 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 SUPERFAMILY SSF56300 782 1022 3.17E-26 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 Gene3D G3DSA:2.60.120.430 603 767 2.5E-27 T 28-03-2018 CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 Gene3D G3DSA:2.60.40.1080 544 602 7.7E-4 T 28-03-2018 CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 Gene3D G3DSA:2.60.40.1080 425 516 4.7E-4 T 28-03-2018 CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 Gene3D G3DSA:2.60.40.1080 1030 1123 3.3E-5 T 28-03-2018 CNX65_RS12805 0a44a335cb5c5e0f148635e505da763c 1126 Pfam PF00149 Calcineurin-like phosphoesterase 785 977 3.4E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS28965 70f8e31bcd86774668e05a626c795518 293 SUPERFAMILY SSF46785 139 225 1.51E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28965 70f8e31bcd86774668e05a626c795518 293 Pfam PF03551 Transcriptional regulator PadR-like family 154 223 1.2E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS28965 70f8e31bcd86774668e05a626c795518 293 Gene3D G3DSA:1.10.10.10 138 267 5.1E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 SMART SM00411 1 89 1.5E-34 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 Pfam PF00216 Bacterial DNA-binding protein 1 88 2.0E-25 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 SUPERFAMILY SSF47729 1 92 2.06E-25 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 Gene3D G3DSA:4.10.520.10 1 96 7.0E-26 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 45 64 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 PRINTS PR01727 Prokaryotic integration host factor signature 39 54 6.2E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 PRINTS PR01727 Prokaryotic integration host factor signature 57 70 6.2E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS29520 6bc6c94ef0d924469211aa9473e237b6 290 PRINTS PR01727 Prokaryotic integration host factor signature 73 87 6.2E-14 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 48 75 - T 28-03-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 Gene3D G3DSA:3.40.50.150 9 217 4.3E-48 T 28-03-2018 CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 275 7.6E-48 T 28-03-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 Gene3D G3DSA:1.10.8.100 218 278 5.2E-18 T 28-03-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 16 278 48.096 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 16 275 9.7E-74 T 28-03-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 SMART SM00650 32 207 3.0E-68 T 28-03-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 CNX65_RS03185 2b813dc9dd68301888f3e02b245fb870 280 SUPERFAMILY SSF53335 16 276 1.91E-64 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS16980 393bfecab8fa0cd5cf3d6edc0ae49e6c 186 Gene3D G3DSA:3.40.430.10 2 183 2.0E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS16980 393bfecab8fa0cd5cf3d6edc0ae49e6c 186 Pfam PF01872 RibD C-terminal domain 2 180 5.3E-22 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS16980 393bfecab8fa0cd5cf3d6edc0ae49e6c 186 SUPERFAMILY SSF53597 2 184 8.12E-32 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 Gene3D G3DSA:1.20.1250.20 10 213 1.3E-20 T 28-03-2018 CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 Gene3D G3DSA:1.20.1250.20 220 414 6.4E-9 T 28-03-2018 CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 SUPERFAMILY SSF103473 21 411 3.27E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 357 380 7.3E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 23 45 7.3E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 59 77 7.3E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 PRINTS PR01988 Putative bacilysin exporter bacE signature 152 173 7.3E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS18095 13d70a470f3a5c0bbfbe73299f9b8b68 416 Pfam PF05977 Transmembrane secretion effector 13 402 7.3E-27 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 SUPERFAMILY SSF52540 402 607 1.9E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 Gene3D G3DSA:3.40.50.300 399 613 1.8E-47 T 28-03-2018 CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 Pfam PF00664 ABC transporter transmembrane region 21 273 8.9E-10 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 Gene3D G3DSA:1.20.1560.10 2 305 8.2E-28 T 28-03-2018 CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 Pfam PF00005 ABC transporter 415 548 4.4E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 SMART SM00382 424 594 8.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 SUPERFAMILY SSF90123 9 303 4.84E-32 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS06520 0c1a6997e2106050cc7f08ceb160dc58 615 ProSitePatterns PS00211 ABC transporters family signature. 520 534 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 Pfam PF12802 MarR family 39 97 1.3E-14 T 28-03-2018 CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 2.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 2.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 2.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 Gene3D G3DSA:1.10.10.10 3 151 1.1E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 SMART SM00418 34 115 0.0071 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 SUPERFAMILY SSF46785 5 148 2.03E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24190 1888ae59b27e41ae45abcc193d336872 151 SMART SM00347 34 134 1.2E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 Gene3D G3DSA:3.40.50.2300 98 223 6.9E-27 T 28-03-2018 CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 SUPERFAMILY SSF46785 9 90 1.31E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 100 218 1.2E-15 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 Pfam PF12840 Helix-turn-helix domain 14 70 2.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 SMART SM00418 14 89 1.2E-5 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 Gene3D G3DSA:1.10.10.10 12 97 1.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 SUPERFAMILY SSF52788 98 219 1.02E-25 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS19425 677b3e24caf4bb03f9932dc8e07b3aad 226 SMART SM00226 98 221 1.0E-20 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 SMART SM00881 104 204 1.6E-18 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 Pfam PF06971 Putative DNA-binding protein N-terminus 30 77 2.4E-18 T 28-03-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 SUPERFAMILY SSF51735 106 228 1.97E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 SUPERFAMILY SSF46785 31 103 8.43E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 Pfam PF02629 CoA binding domain 106 203 6.4E-20 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 Gene3D G3DSA:3.40.50.720 101 245 2.4E-17 T 28-03-2018 CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 Gene3D G3DSA:1.10.10.10 28 98 5.0E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33170 9725f76643622d6ccfc378e907d45239 256 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 25 233 35.137 T 28-03-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 SUPERFAMILY SSF50331 243 364 6.66E-19 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 40 365 1.5E-113 T 28-03-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 Pfam PF08402 TOBE domain 285 365 3.6E-18 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 Gene3D G3DSA:2.40.50.140 294 358 6.5E-6 T 28-03-2018 CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 SUPERFAMILY SSF52540 11 248 1.43E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 Pfam PF00005 ABC transporter 26 167 8.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 SMART SM00382 34 263 2.9E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 Gene3D G3DSA:2.40.50.100 245 293 9.8E-7 T 28-03-2018 CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 Gene3D G3DSA:3.40.50.300 6 244 1.1E-67 T 28-03-2018 CNX65_RS28940 26d3bcf1cc7b1b0e6fc22ffeb004afb7 371 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS16585 587baeeb2aa274f2dd6006569e178a2f 256 Gene3D G3DSA:1.10.10.60 3 78 3.9E-13 T 28-03-2018 CNX65_RS16585 587baeeb2aa274f2dd6006569e178a2f 256 Pfam PF00440 Bacterial regulatory proteins, tetR family 37 81 4.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16585 587baeeb2aa274f2dd6006569e178a2f 256 SUPERFAMILY SSF48498 101 205 1.52E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS16585 587baeeb2aa274f2dd6006569e178a2f 256 Pfam PF13305 WHG domain 112 170 3.3E-8 T 28-03-2018 IPR025996 WHG domain CNX65_RS16585 587baeeb2aa274f2dd6006569e178a2f 256 Gene3D G3DSA:1.10.357.10 79 210 2.9E-16 T 28-03-2018 CNX65_RS16585 587baeeb2aa274f2dd6006569e178a2f 256 SUPERFAMILY SSF46689 27 95 2.41E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14085 07b63666e6a1144610cc83022b82f4a0 302 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 293 5.1E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS14085 07b63666e6a1144610cc83022b82f4a0 302 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 35 48 - T 28-03-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 CNX65_RS14085 07b63666e6a1144610cc83022b82f4a0 302 SUPERFAMILY SSF53686 6 300 4.06E-72 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS14085 07b63666e6a1144610cc83022b82f4a0 302 Gene3D G3DSA:3.40.50.1100 128 294 3.1E-36 T 28-03-2018 CNX65_RS14085 07b63666e6a1144610cc83022b82f4a0 302 Gene3D G3DSA:3.40.50.1100 29 127 1.3E-26 T 28-03-2018 CNX65_RS08670 dc6cf5e0ff1c1de0d4760dde15284a9f 365 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 361 5.8E-112 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS08670 dc6cf5e0ff1c1de0d4760dde15284a9f 365 SUPERFAMILY SSF53383 15 364 4.76E-100 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS08670 dc6cf5e0ff1c1de0d4760dde15284a9f 365 Gene3D G3DSA:3.90.1150.10 239 365 3.5E-42 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS08670 dc6cf5e0ff1c1de0d4760dde15284a9f 365 PIRSF PIRSF000390 5 365 5.6E-97 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS08670 dc6cf5e0ff1c1de0d4760dde15284a9f 365 Gene3D G3DSA:3.40.640.10 3 238 7.0E-46 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS09320 2366eede428d1dbee739e7d37e16eaf1 405 Pfam PF02653 Branched-chain amino acid transport system / permease component 54 395 4.4E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS09320 2366eede428d1dbee739e7d37e16eaf1 405 Gene3D G3DSA:1.10.3470.10 47 404 6.4E-23 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS30460 1a033b571398092cfb3488bb8692688b 329 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 326 1.7E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS30460 1a033b571398092cfb3488bb8692688b 329 Gene3D G3DSA:1.10.3720.10 2 315 3.5E-31 T 28-03-2018 CNX65_RS30460 1a033b571398092cfb3488bb8692688b 329 SUPERFAMILY SSF161098 99 309 3.27E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS34750 c9ab81fc9ee2e356514499d90ff8364c 127 Pfam PF17249 Family of unknown function (DUF5318) 1 122 5.7E-66 T 28-03-2018 IPR035169 Protein of unknown function DUF5318 CNX65_RS33940 4fe9fdf2d310f31095ce1643318e2452 480 Gene3D G3DSA:1.10.287.1060 30 108 1.8E-5 T 28-03-2018 CNX65_RS33940 4fe9fdf2d310f31095ce1643318e2452 480 SUPERFAMILY SSF140459 14 190 5.49E-14 T 28-03-2018 CNX65_RS33940 4fe9fdf2d310f31095ce1643318e2452 480 Pfam PF00823 PPE family 16 174 1.6E-9 T 28-03-2018 IPR000030 PPE family CNX65_RS07735 93a0b9a84b977272b1d8ad06e0d92ebb 265 Pfam PF05114 Protein of unknown function (DUF692) 5 263 1.9E-85 T 28-03-2018 IPR007801 Uncharacterised protein family UPF0276 CNX65_RS07735 93a0b9a84b977272b1d8ad06e0d92ebb 265 Gene3D G3DSA:3.20.20.150 1 265 2.4E-76 T 28-03-2018 CNX65_RS07735 93a0b9a84b977272b1d8ad06e0d92ebb 265 SUPERFAMILY SSF51658 23 216 7.27E-18 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS25335 d2079dcb9ed8eced360c3c2ed259c05e 217 Gene3D G3DSA:3.40.50.1000 70 210 7.6E-23 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS25335 d2079dcb9ed8eced360c3c2ed259c05e 217 Gene3D G3DSA:1.10.150.240 19 69 1.3E-19 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CNX65_RS25335 d2079dcb9ed8eced360c3c2ed259c05e 217 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 99 173 7.1E-8 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS25335 d2079dcb9ed8eced360c3c2ed259c05e 217 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 178 7.7E-20 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS25335 d2079dcb9ed8eced360c3c2ed259c05e 217 SUPERFAMILY SSF56784 3 207 5.97E-40 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS22690 2ad8fdd5f4b28be623cbc92b969c9b70 384 Gene3D G3DSA:1.10.443.10 165 368 1.9E-32 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS22690 2ad8fdd5f4b28be623cbc92b969c9b70 384 Pfam PF00589 Phage integrase family 167 358 1.0E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS22690 2ad8fdd5f4b28be623cbc92b969c9b70 384 Gene3D G3DSA:1.10.150.130 19 156 1.4E-10 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS22690 2ad8fdd5f4b28be623cbc92b969c9b70 384 SUPERFAMILY SSF56349 168 368 6.77E-31 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS32800 6fc216aedd254130fbd10a53428df21a 289 Gene3D G3DSA:3.30.2010.10 58 151 1.6E-22 T 28-03-2018 CNX65_RS32800 6fc216aedd254130fbd10a53428df21a 289 Hamap MF_00188 Protease HtpX [htpX]. 7 285 27.027 T 28-03-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 CNX65_RS32800 6fc216aedd254130fbd10a53428df21a 289 Pfam PF01435 Peptidase family M48 68 285 9.0E-36 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 Gene3D G3DSA:3.40.50.300 279 428 7.3E-19 T 28-03-2018 CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 TIGRFAM TIGR03817 DECH_helic: helicase/secretion neighborhood putative DEAH-box helicase 23 768 0.0 T 28-03-2018 IPR022307 DEAD/DEAH-box helicase, putative, actinobacteria CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 Pfam PF00271 Helicase conserved C-terminal domain 289 397 8.8E-10 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 Gene3D G3DSA:3.40.50.300 20 250 1.6E-30 T 28-03-2018 CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 Pfam PF00270 DEAD/DEAH box helicase 62 227 7.1E-22 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 SMART SM00490 316 397 1.9E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 Pfam PF09369 Domain of unknown function (DUF1998) 662 741 4.0E-18 T 28-03-2018 IPR018973 DEAD/DEAH-box helicase, putative CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 SUPERFAMILY SSF52540 261 406 6.1E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 SUPERFAMILY SSF52540 69 229 6.1E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01460 0df11af8046d822546a61881d55ebc35 805 SMART SM00487 55 256 3.0E-27 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 4 628 2.4E-217 T 28-03-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 Gene3D G3DSA:3.50.50.60 244 552 0.0081 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 420 442 2.4E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 86 106 2.4E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 60 84 2.4E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 264 286 2.4E-8 T 28-03-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 66 123 2.1E-23 T 28-03-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 314 326 2.3E-59 T 28-03-2018 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 421 440 2.3E-59 T 28-03-2018 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 159 180 2.3E-59 T 28-03-2018 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 224 245 2.3E-59 T 28-03-2018 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 246 272 2.3E-59 T 28-03-2018 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 84 109 2.3E-59 T 28-03-2018 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 112 132 2.3E-59 T 28-03-2018 CNX65_RS32875 b9a9064c23554d875c8b027bb69a62da 635 Pfam PF00361 Proton-conducting membrane transporter 138 420 2.1E-84 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1248 1262 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 800 814 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:3.40.50.300 135 363 6.8E-7 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SUPERFAMILY SSF50978 1141 1310 2.93E-66 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SUPERFAMILY SSF50978 922 1037 2.93E-66 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 844 858 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 936 950 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 969 995 0.0061 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 1276 1306 1.2E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 791 813 0.0012 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 920 949 1.0E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 1181 1215 1.0E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 687 721 5.4E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 824 857 7.6E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 1229 1261 8.5E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 1138 1170 5.9E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 1001 1033 0.02 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 735 767 9.6E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF00400 WD domain, G-beta repeat 871 903 1.2E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.140.10.10 1097 1236 1.1E-31 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.80.10.50 1002 1027 1.2E-5 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1157 1171 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1111 1125 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 PRINTS PR00320 G protein beta WD-40 repeat signature 1020 1034 3.2E-8 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 PRINTS PR00320 G protein beta WD-40 repeat signature 708 722 3.2E-8 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 PRINTS PR00320 G protein beta WD-40 repeat signature 844 858 3.2E-8 T 28-03-2018 IPR020472 G-protein beta WD-40 repeat CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:1.10.10.670 854 915 1.1E-16 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:1.10.10.670 813 853 4.5E-14 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:1.10.10.670 1028 1092 9.3E-8 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 890 904 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 754 768 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1202 1216 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Pfam PF13191 AAA ATPase domain 147 307 3.7E-8 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SUPERFAMILY SSF52540 143 379 7.24E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 1093 1124 210.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 956 995 0.0026 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 1267 1307 1.0E-5 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 1042 1080 12.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 864 903 1.1E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 910 949 1.9E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 996 1033 1.3 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 682 721 2.8E-8 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 773 813 8.6E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 819 857 3.2E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 1222 1261 3.1E-7 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 1176 1215 4.8E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 728 767 1.0E-9 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SMART SM00320 1131 1170 1.6E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SUPERFAMILY SSF50978 682 997 4.58E-76 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.40.10.120 916 960 2.3E-14 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.40.10.120 961 1001 3.3E-9 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.40.10.120 1237 1273 1.1E-11 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.40.10.120 733 778 5.3E-15 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.40.10.120 684 732 4.0E-17 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.40.10.120 784 812 7.1E-13 T 28-03-2018 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 Gene3D G3DSA:2.130.10.10 1274 1326 7.8E-8 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 708 722 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 1020 1034 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS02865 61fd6bdd688e29ecdfb0ae374df43d4a 1344 SUPERFAMILY SSF50965 1055 1173 1.96E-12 T 28-03-2018 IPR011043 Galactose oxidase/kelch, beta-propeller CNX65_RS27700 5a08c3ff8fa21f3342261ad770a0fa1c 137 Pfam PF02675 S-adenosylmethionine decarboxylase 18 124 1.3E-34 T 28-03-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CNX65_RS27700 5a08c3ff8fa21f3342261ad770a0fa1c 137 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 12 128 24.954 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CNX65_RS27700 5a08c3ff8fa21f3342261ad770a0fa1c 137 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 15 124 2.2E-35 T 28-03-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 CNX65_RS27700 5a08c3ff8fa21f3342261ad770a0fa1c 137 SUPERFAMILY SSF56276 15 125 7.85E-34 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CNX65_RS27700 5a08c3ff8fa21f3342261ad770a0fa1c 137 Gene3D G3DSA:3.60.90.10 8 130 7.5E-39 T 28-03-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 CNX65_RS24140 04c9ef7a3b6d1d80e9dc50aacd52df94 338 Gene3D G3DSA:3.40.190.10 136 338 1.3E-25 T 28-03-2018 CNX65_RS24140 04c9ef7a3b6d1d80e9dc50aacd52df94 338 Gene3D G3DSA:3.40.190.10 2 124 9.3E-17 T 28-03-2018 CNX65_RS24140 04c9ef7a3b6d1d80e9dc50aacd52df94 338 SMART SM00062 40 261 9.4E-4 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS24140 04c9ef7a3b6d1d80e9dc50aacd52df94 338 Pfam PF09084 NMT1/THI5 like 51 257 6.6E-40 T 28-03-2018 IPR015168 SsuA/THI5-like CNX65_RS24140 04c9ef7a3b6d1d80e9dc50aacd52df94 338 SUPERFAMILY SSF53850 39 271 1.37E-42 T 28-03-2018 CNX65_RS25820 7b68780be51abe7988c5eecf1e5eefd8 259 TIGRFAM TIGR01198 pgl: 6-phosphogluconolactonase 8 250 2.3E-73 T 28-03-2018 IPR005900 6-phosphogluconolactonase, DevB-type GO:0005975|GO:0006098|GO:0017057 KEGG: 00030+3.1.1.31 CNX65_RS25820 7b68780be51abe7988c5eecf1e5eefd8 259 Pfam PF01182 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase 11 240 2.2E-72 T 28-03-2018 IPR006148 Glucosamine/galactosamine-6-phosphate isomerase GO:0005975 KEGG: 00520+3.5.99.6|MetaCyc: PWY-5514|MetaCyc: PWY-6855|MetaCyc: PWY-6906 CNX65_RS25820 7b68780be51abe7988c5eecf1e5eefd8 259 SUPERFAMILY SSF100950 5 252 1.5E-63 T 28-03-2018 CNX65_RS25820 7b68780be51abe7988c5eecf1e5eefd8 259 Gene3D G3DSA:3.40.50.1360 1 255 4.7E-79 T 28-03-2018 CNX65_RS29585 e045e74de77ab5e60dd6f87e480bb34e 345 Gene3D G3DSA:3.40.718.10 1 330 3.4E-106 T 28-03-2018 CNX65_RS29585 e045e74de77ab5e60dd6f87e480bb34e 345 Hamap MF_01035 3-isopropylmalate dehydrogenase [leuB]. 1 338 57.709 T 28-03-2018 IPR023698 3-isopropylmalate dehydrogenase GO:0003862|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 CNX65_RS29585 e045e74de77ab5e60dd6f87e480bb34e 345 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 317 3.5E-86 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CNX65_RS29585 e045e74de77ab5e60dd6f87e480bb34e 345 SMART SM01329 2 334 2.0E-160 T 28-03-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 CNX65_RS29585 e045e74de77ab5e60dd6f87e480bb34e 345 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 232 251 - T 28-03-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 CNX65_RS29585 e045e74de77ab5e60dd6f87e480bb34e 345 SUPERFAMILY SSF53659 2 329 1.03E-107 T 28-03-2018 CNX65_RS28810 62abd945248392823d26f7006daab542 210 Gene3D G3DSA:2.160.10.10 3 204 4.1E-38 T 28-03-2018 CNX65_RS28810 62abd945248392823d26f7006daab542 210 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 104 138 2.5E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS28810 62abd945248392823d26f7006daab542 210 SUPERFAMILY SSF51161 38 197 1.03E-42 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS10740 6dbcc98b5aae637d1e854b7a475a5288 322 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 37 322 7.6E-145 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10740 6dbcc98b5aae637d1e854b7a475a5288 322 SUPERFAMILY SSF51366 46 295 9.42E-63 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS10740 6dbcc98b5aae637d1e854b7a475a5288 322 Gene3D G3DSA:3.20.20.70 46 299 2.9E-67 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS10740 6dbcc98b5aae637d1e854b7a475a5288 322 PIRSF PIRSF029271 25 322 3.9E-150 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10740 6dbcc98b5aae637d1e854b7a475a5288 322 Pfam PF01680 SOR/SNZ family 35 240 2.5E-106 T 28-03-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10740 6dbcc98b5aae637d1e854b7a475a5288 322 ProSitePatterns PS01235 PdxS/SNZ family signature. 233 251 - T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10740 6dbcc98b5aae637d1e854b7a475a5288 322 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 32 322 52.846 T 28-03-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS06015 e21f5aeb07054990faf72e623a1a5d82 86 Pfam PF01649 Ribosomal protein S20 2 84 7.5E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS06015 e21f5aeb07054990faf72e623a1a5d82 86 Gene3D G3DSA:1.20.58.110 1 86 8.0E-30 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS06015 e21f5aeb07054990faf72e623a1a5d82 86 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 84 3.0E-24 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS06015 e21f5aeb07054990faf72e623a1a5d82 86 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 17.483 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS06015 e21f5aeb07054990faf72e623a1a5d82 86 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 12 86 8.0E-24 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS06015 e21f5aeb07054990faf72e623a1a5d82 86 SUPERFAMILY SSF46992 3 86 2.62E-28 T 28-03-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30930 ebca85d25a67ce0ad4b065a7e0cec7ad 106 Pfam PF00717 Peptidase S24-like 3 63 1.8E-10 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS30930 ebca85d25a67ce0ad4b065a7e0cec7ad 106 Gene3D G3DSA:2.10.109.10 1 89 2.2E-17 T 28-03-2018 CNX65_RS30930 ebca85d25a67ce0ad4b065a7e0cec7ad 106 SUPERFAMILY SSF51306 2 91 7.46E-16 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS26315 57173dab5f9247da0214fba37f5ba728 234 SUPERFAMILY SSF56214 116 229 3.53E-13 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS26315 57173dab5f9247da0214fba37f5ba728 234 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 118 203 3.4E-11 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS26315 57173dab5f9247da0214fba37f5ba728 234 Gene3D G3DSA:3.90.470.20 127 212 2.0E-8 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS26315 57173dab5f9247da0214fba37f5ba728 234 Gene3D G3DSA:3.90.470.20 30 126 3.3E-16 T 28-03-2018 IPR008278 4'-phosphopantetheinyl transferase superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|Reactome: R-HSA-199220 CNX65_RS26315 57173dab5f9247da0214fba37f5ba728 234 PRINTS PR01399 Enterobactin synthetase component D signature 83 101 2.7E-25 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CNX65_RS26315 57173dab5f9247da0214fba37f5ba728 234 PRINTS PR01399 Enterobactin synthetase component D signature 160 176 2.7E-25 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CNX65_RS26315 57173dab5f9247da0214fba37f5ba728 234 PRINTS PR01399 Enterobactin synthetase component D signature 53 73 2.7E-25 T 28-03-2018 IPR003542 Enterobactin synthetase-like, component D GO:0009239|GO:0009366|GO:0016780 CNX65_RS02255 71dfcc92f7c35bf5bb3007d0fd4f645b 201 Pfam PF04542 Sigma-70 region 2 40 102 4.3E-9 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02255 71dfcc92f7c35bf5bb3007d0fd4f645b 201 SUPERFAMILY SSF88659 126 195 1.94E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02255 71dfcc92f7c35bf5bb3007d0fd4f645b 201 SUPERFAMILY SSF88946 23 119 1.02E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS02255 71dfcc92f7c35bf5bb3007d0fd4f645b 201 Gene3D G3DSA:1.10.10.10 119 201 8.6E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02255 71dfcc92f7c35bf5bb3007d0fd4f645b 201 Gene3D G3DSA:1.10.1740.10 17 118 3.1E-18 T 28-03-2018 CNX65_RS02255 71dfcc92f7c35bf5bb3007d0fd4f645b 201 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 36 193 4.7E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 Gene3D G3DSA:1.10.1660.10 66 120 4.5E-8 T 28-03-2018 CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 Gene3D G3DSA:3.20.80.10 121 268 6.3E-17 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 SUPERFAMILY SSF46955 5 113 1.1E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 SMART SM00871 119 267 2.2E-6 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 SUPERFAMILY SSF55136 120 253 4.97E-8 T 28-03-2018 CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 Pfam PF13411 MerR HTH family regulatory protein 6 73 2.5E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 SMART SM00422 5 75 2.1E-14 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 Gene3D G3DSA:1.10.1660.10 3 65 9.5E-18 T 28-03-2018 CNX65_RS23065 a8a69afdd2b70e3d157105962ba48638 278 Pfam PF06445 GyrI-like small molecule binding domain 121 259 3.9E-10 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CNX65_RS15630 8722be22e062e4dea913cce677071cdb 521 Gene3D G3DSA:3.40.605.10 25 297 2.9E-76 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS15630 8722be22e062e4dea913cce677071cdb 521 SUPERFAMILY SSF53720 36 516 1.83E-136 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS15630 8722be22e062e4dea913cce677071cdb 521 Gene3D G3DSA:3.40.309.10 298 494 1.7E-62 T 28-03-2018 CNX65_RS15630 8722be22e062e4dea913cce677071cdb 521 Pfam PF00171 Aldehyde dehydrogenase family 52 512 9.4E-139 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS15630 8722be22e062e4dea913cce677071cdb 521 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 309 320 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS30330 47aa3a7a10f08db1e6adfee874e2b91b 305 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 22 294 4.2E-77 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CNX65_RS30330 47aa3a7a10f08db1e6adfee874e2b91b 305 Pfam PF01545 Cation efflux family 23 214 6.8E-43 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CNX65_RS30330 47aa3a7a10f08db1e6adfee874e2b91b 305 SUPERFAMILY SSF160240 219 294 8.24E-7 T 28-03-2018 CNX65_RS30330 47aa3a7a10f08db1e6adfee874e2b91b 305 Gene3D G3DSA:1.20.1510.10 20 215 2.2E-51 T 28-03-2018 CNX65_RS30330 47aa3a7a10f08db1e6adfee874e2b91b 305 Gene3D G3DSA:3.30.70.1350 217 297 5.0E-12 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CNX65_RS30330 47aa3a7a10f08db1e6adfee874e2b91b 305 SUPERFAMILY SSF161111 22 216 2.22E-49 T 28-03-2018 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 PIRSF PIRSF001438 1 313 4.8E-103 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 5 299 6.8E-87 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 223 299 4.5E-18 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 Gene3D G3DSA:3.30.160.40 217 307 2.8E-17 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 SUPERFAMILY SSF54782 216 303 3.27E-15 T 28-03-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 4 301 33.879 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 227 243 - T 28-03-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 Gene3D G3DSA:3.40.190.10 1 101 1.4E-35 T 28-03-2018 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 5 207 1.4E-65 T 28-03-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 Gene3D G3DSA:3.40.190.10 102 194 9.7E-32 T 28-03-2018 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 SUPERFAMILY SSF53850 3 211 5.65E-65 T 28-03-2018 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 PRINTS PR00151 Porphobilinogen deaminase signature 71 90 1.3E-19 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 PRINTS PR00151 Porphobilinogen deaminase signature 119 136 1.3E-19 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 PRINTS PR00151 Porphobilinogen deaminase signature 138 155 1.3E-19 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33160 c7e5a6eda824481b6fb85e8eaf279421 313 PRINTS PR00151 Porphobilinogen deaminase signature 226 243 1.3E-19 T 28-03-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 SUPERFAMILY SSF103473 39 459 4.45E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 Pfam PF02223 Thymidylate kinase 494 612 5.7E-12 T 28-03-2018 CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 Gene3D G3DSA:1.20.1250.20 253 466 1.5E-17 T 28-03-2018 CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 Pfam PF05977 Transmembrane secretion effector 34 398 1.4E-17 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 SUPERFAMILY SSF52540 640 690 1.14E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 SUPERFAMILY SSF52540 479 609 1.14E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 Gene3D G3DSA:1.20.1250.20 18 246 3.1E-16 T 28-03-2018 CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 Gene3D G3DSA:3.40.50.300 478 615 8.2E-20 T 28-03-2018 CNX65_RS01510 66bdfd262777c9f03fc79755fc98b25d 705 Hamap MF_00165 Thymidylate kinase [tmk]. 481 691 15.399 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 ProSitePatterns PS00591 Glycosyl hydrolases family 10 (GH10) active site. 259 269 - T 28-03-2018 IPR031158 Glycosyl hydrolases family 10, active site MetaCyc: PWY-6784 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 SUPERFAMILY SSF51445 38 332 1.02E-108 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 Pfam PF00553 Cellulose binding domain 364 449 8.1E-18 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 SUPERFAMILY SSF49384 358 454 8.37E-22 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 Pfam PF00331 Glycosyl hydrolase family 10 39 329 2.3E-104 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 Gene3D G3DSA:3.20.20.80 28 341 1.7E-69 T 28-03-2018 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 153 164 4.0E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 111 123 4.0E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 198 209 4.0E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 PRINTS PR00134 Glycosyl hydrolase family 10 signature 227 239 4.0E-16 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 Gene3D G3DSA:2.60.40.290 353 456 6.5E-25 T 28-03-2018 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 SMART SM00637 364 454 2.8E-22 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16380 1ae79fe7c8874b1ab730376f6b924834 457 SMART SM00633 80 331 1.5E-126 T 28-03-2018 IPR001000 Glycoside hydrolase family 10 domain GO:0004553|GO:0005975 MetaCyc: PWY-6784 CNX65_RS10800 759d4ab445ca12fa54208d523f1b0ea5 386 Gene3D G3DSA:1.20.1250.20 187 381 1.8E-13 T 28-03-2018 CNX65_RS10800 759d4ab445ca12fa54208d523f1b0ea5 386 Pfam PF07690 Major Facilitator Superfamily 208 374 3.7E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS10800 759d4ab445ca12fa54208d523f1b0ea5 386 Pfam PF07690 Major Facilitator Superfamily 6 183 7.7E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS10800 759d4ab445ca12fa54208d523f1b0ea5 386 Gene3D G3DSA:1.20.1250.20 1 183 2.1E-13 T 28-03-2018 CNX65_RS10800 759d4ab445ca12fa54208d523f1b0ea5 386 SUPERFAMILY SSF103473 3 374 1.12E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13620 34f7278b42a287368fdba25c1007b74e 308 Gene3D G3DSA:3.40.366.10 1 284 9.3E-27 T 28-03-2018 CNX65_RS13620 34f7278b42a287368fdba25c1007b74e 308 SUPERFAMILY SSF52151 5 126 1.18E-25 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13620 34f7278b42a287368fdba25c1007b74e 308 SUPERFAMILY SSF52151 194 276 1.18E-25 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS30490 578e44df0adac9e40ae3a1441a55db43 258 Gene3D G3DSA:1.10.8.10 25 64 1.2E-7 T 28-03-2018 CNX65_RS30490 578e44df0adac9e40ae3a1441a55db43 258 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 39 250 1.6E-41 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CNX65_RS30490 578e44df0adac9e40ae3a1441a55db43 258 TIGRFAM TIGR03704 PrmC_rel_meth: putative protein-(glutamine-N5) methyltransferase, unknown substrate-specific 11 256 2.0E-107 T 28-03-2018 IPR022446 Conserved hypothetical protein CHP03704, protein-(glutamine-N5) methyltransferase CNX65_RS30490 578e44df0adac9e40ae3a1441a55db43 258 Pfam PF05175 Methyltransferase small domain 68 170 1.5E-10 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CNX65_RS30490 578e44df0adac9e40ae3a1441a55db43 258 SUPERFAMILY SSF53335 35 249 4.18E-46 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS30490 578e44df0adac9e40ae3a1441a55db43 258 Gene3D G3DSA:3.40.50.150 65 255 4.9E-41 T 28-03-2018 CNX65_RS13615 138a079a3b105a68ca01918aebe167dd 507 SUPERFAMILY SSF56801 8 506 3.01E-105 T 28-03-2018 CNX65_RS13615 138a079a3b105a68ca01918aebe167dd 507 Gene3D G3DSA:3.40.50.980 169 326 6.9E-31 T 28-03-2018 CNX65_RS13615 138a079a3b105a68ca01918aebe167dd 507 Gene3D G3DSA:3.40.50.980 5 168 3.1E-35 T 28-03-2018 CNX65_RS13615 138a079a3b105a68ca01918aebe167dd 507 Pfam PF00501 AMP-binding enzyme 19 415 3.0E-66 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS13615 138a079a3b105a68ca01918aebe167dd 507 Gene3D G3DSA:2.30.38.10 332 406 2.4E-17 T 28-03-2018 CNX65_RS13615 138a079a3b105a68ca01918aebe167dd 507 Gene3D G3DSA:3.30.300.30 411 507 5.2E-20 T 28-03-2018 CNX65_RS13615 138a079a3b105a68ca01918aebe167dd 507 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS23715 fe0f9175c3ca8d79975a5d66e0d7f806 598 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 215 256 1.8E-14 T 28-03-2018 IPR022435 Surface-anchored repeat, actinobacteria CNX65_RS23715 fe0f9175c3ca8d79975a5d66e0d7f806 598 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 485 523 1.1E-8 T 28-03-2018 IPR022435 Surface-anchored repeat, actinobacteria CNX65_RS23715 fe0f9175c3ca8d79975a5d66e0d7f806 598 TIGRFAM TIGR03773 anch_rpt_wall: putative ABC transporter-associated repeat protein 98 598 8.3E-92 T 28-03-2018 IPR022395 Conserved hypothetical protein CHP03773, ABC transporter-like CNX65_RS01270 a24d94937b67f1b737e9d5016df05cc7 308 Gene3D G3DSA:1.10.8.10 277 302 0.016 T 28-03-2018 CNX65_RS01270 a24d94937b67f1b737e9d5016df05cc7 308 Gene3D G3DSA:1.10.8.10 247 275 3.8E-6 T 28-03-2018 CNX65_RS01270 a24d94937b67f1b737e9d5016df05cc7 308 ProSitePatterns PS01272 Glucokinase regulatory protein family signature. 189 206 - T 28-03-2018 IPR005486 Glucokinase regulatory protein, conserved site KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126|Reactome: R-HSA-170822|Reactome: R-HSA-5619107 CNX65_RS01270 a24d94937b67f1b737e9d5016df05cc7 308 SUPERFAMILY SSF53697 14 253 5.12E-59 T 28-03-2018 CNX65_RS01270 a24d94937b67f1b737e9d5016df05cc7 308 Gene3D G3DSA:3.40.50.10490 10 246 4.5E-45 T 28-03-2018 CNX65_RS01270 a24d94937b67f1b737e9d5016df05cc7 308 Pfam PF13580 SIS domain 52 166 1.3E-8 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS01270 a24d94937b67f1b737e9d5016df05cc7 308 Hamap MF_00068 N-acetylmuramic acid 6-phosphate etherase [murQ]. 8 299 34.853 T 28-03-2018 IPR005488 N-acetylmuramic acid 6-phosphate etherase MurQ GO:0016835|GO:0046348 KEGG: 00030+4.2.1.12|KEGG: 00520+4.2.1.126 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Gene3D G3DSA:3.40.50.720 1135 1396 1.5E-55 T 28-03-2018 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SMART SM00825 Beta-ketoacyl synthase 38 463 1.9E-210 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Gene3D G3DSA:3.40.366.10 725 848 6.4E-28 T 28-03-2018 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Gene3D G3DSA:3.40.366.10 543 724 4.9E-50 T 28-03-2018 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SUPERFAMILY SSF51735 1138 1382 4.14E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Gene3D G3DSA:3.40.47.10 28 297 8.2E-81 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Pfam PF00698 Acyl transferase domain 559 860 1.1E-77 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Pfam PF08990 Erythronolide synthase docking 6 29 6.7E-11 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SMART SM00823 Phosphopantetheine attachment site 1425 1497 7.1E-32 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Pfam PF00550 Phosphopantetheine attachment site 1427 1493 2.6E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SUPERFAMILY SSF47336 1417 1508 1.7E-23 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Pfam PF08659 KR domain 1143 1321 3.7E-54 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SUPERFAMILY SSF51735 951 1131 1.89E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 560 842 3.9E-107 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SMART SM01294 1426 1493 2.7E-4 T 28-03-2018 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Gene3D G3DSA:3.40.47.10 300 461 5.7E-62 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SUPERFAMILY SSF52151 556 681 3.66E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SUPERFAMILY SSF52151 736 838 3.66E-68 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1452 1467 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SUPERFAMILY SSF53901 33 407 2.89E-102 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1143 1323 3.7E-46 T 28-03-2018 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Gene3D G3DSA:1.10.1200.10 1397 1503 5.4E-22 T 28-03-2018 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 198 214 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 497 1.0E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 293 410 2.2E-44 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 SUPERFAMILY SSF55048 679 730 4.71E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS16145 bcc2410b665ec6f478fa7d9957970928 1589 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 36 285 1.7E-85 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS06410 c5dbd8ce484bbfaea8677d0d56c8761e 148 Pfam PF01638 HxlR-like helix-turn-helix 53 140 4.9E-28 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS06410 c5dbd8ce484bbfaea8677d0d56c8761e 148 SUPERFAMILY SSF46785 42 144 1.34E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06410 c5dbd8ce484bbfaea8677d0d56c8761e 148 Gene3D G3DSA:1.10.10.10 51 147 1.1E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27345 4390056b20456088dff713b59ae62da5 377 Gene3D G3DSA:3.40.640.10 45 257 2.3E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS27345 4390056b20456088dff713b59ae62da5 377 Pfam PF00155 Aminotransferase class I and II 41 373 3.1E-38 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS27345 4390056b20456088dff713b59ae62da5 377 Gene3D G3DSA:3.90.1150.10 258 377 1.5E-33 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS27345 4390056b20456088dff713b59ae62da5 377 SUPERFAMILY SSF53383 4 377 7.93E-103 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS30400 bc9d31fa5ab0203d510d54835d243a52 165 SUPERFAMILY SSF55136 4 144 1.36E-14 T 28-03-2018 CNX65_RS30400 bc9d31fa5ab0203d510d54835d243a52 165 Gene3D G3DSA:3.20.80.10 1 153 2.6E-21 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CNX65_RS30400 bc9d31fa5ab0203d510d54835d243a52 165 SMART SM00871 3 152 1.1E-5 T 28-03-2018 IPR010499 Bacterial transcription activator, effector binding CNX65_RS30400 bc9d31fa5ab0203d510d54835d243a52 165 Pfam PF06445 GyrI-like small molecule binding domain 4 151 5.4E-10 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CNX65_RS28555 10785d8709953f54dc355bc821539aac 461 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 68 91 - T 28-03-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 CNX65_RS28555 10785d8709953f54dc355bc821539aac 461 Gene3D G3DSA:3.30.830.10 30 255 7.5E-58 T 28-03-2018 CNX65_RS28555 10785d8709953f54dc355bc821539aac 461 SUPERFAMILY SSF63411 267 451 1.32E-48 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CNX65_RS28555 10785d8709953f54dc355bc821539aac 461 Pfam PF05193 Peptidase M16 inactive domain 201 380 9.0E-40 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CNX65_RS28555 10785d8709953f54dc355bc821539aac 461 SUPERFAMILY SSF63411 37 240 3.14E-55 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CNX65_RS28555 10785d8709953f54dc355bc821539aac 461 Pfam PF00675 Insulinase (Peptidase family M16) 47 193 2.8E-39 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CNX65_RS28555 10785d8709953f54dc355bc821539aac 461 Gene3D G3DSA:3.30.830.10 256 452 7.0E-48 T 28-03-2018 CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 SUPERFAMILY SSF81606 189 385 1.83E-10 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 Pfam PF13426 PAS domain 38 140 7.6E-8 T 28-03-2018 IPR000014 PAS domain CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 Gene3D G3DSA:3.60.40.10 157 388 1.9E-34 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 SUPERFAMILY SSF55785 27 130 3.14E-12 T 28-03-2018 IPR000014 PAS domain CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 SMART SM00331 184 388 1.2E-25 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 214 385 2.0E-27 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 Gene3D G3DSA:3.30.450.20 25 156 6.1E-16 T 28-03-2018 CNX65_RS19220 9fe32294b1dc390c6a4fc1ad3b773e99 391 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 32 151 5.5E-9 T 28-03-2018 IPR000014 PAS domain CNX65_RS16630 f6829dd7912f7ebd57af3596e2267ddf 410 Pfam PF13203 Putative metallopeptidase domain 12 269 7.9E-20 T 28-03-2018 IPR025154 Putative metallopeptidase domain CNX65_RS16630 f6829dd7912f7ebd57af3596e2267ddf 410 Pfam PF09967 VWA-like domain (DUF2201) 275 380 2.8E-13 T 28-03-2018 IPR018698 VWA-like domain CNX65_RS16630 f6829dd7912f7ebd57af3596e2267ddf 410 Gene3D G3DSA:3.40.50.410 264 393 3.9E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS16630 f6829dd7912f7ebd57af3596e2267ddf 410 SUPERFAMILY SSF53300 269 373 3.71E-9 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS32565 1e40951f8747a7d7a826a801152acef7 184 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 1 158 24.951 T 28-03-2018 IPR022973 Ribosomal protein L10 CNX65_RS32565 1e40951f8747a7d7a826a801152acef7 184 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 66 150 0.008 T 28-03-2018 CNX65_RS32565 1e40951f8747a7d7a826a801152acef7 184 SUPERFAMILY SSF160369 1 169 5.23E-51 T 28-03-2018 CNX65_RS32565 1e40951f8747a7d7a826a801152acef7 184 Pfam PF00466 Ribosomal protein L10 2 98 5.1E-24 T 28-03-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 CNX65_RS01160 d27f1b77de3f4bb6359a214b4fc53918 296 Gene3D G3DSA:3.40.50.720 3 156 2.7E-33 T 28-03-2018 CNX65_RS01160 d27f1b77de3f4bb6359a214b4fc53918 296 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 8 123 4.3E-17 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS01160 d27f1b77de3f4bb6359a214b4fc53918 296 SUPERFAMILY SSF51735 5 137 1.32E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS01160 d27f1b77de3f4bb6359a214b4fc53918 296 SUPERFAMILY SSF55347 137 246 1.18E-7 T 28-03-2018 CNX65_RS01160 d27f1b77de3f4bb6359a214b4fc53918 296 Gene3D G3DSA:3.30.360.10 157 295 7.9E-9 T 28-03-2018 CNX65_RS04315 bbb104fd0692bfae7401857d258d7c19 285 Gene3D G3DSA:3.30.200.20 22 87 1.2E-8 T 28-03-2018 CNX65_RS04315 bbb104fd0692bfae7401857d258d7c19 285 Gene3D G3DSA:3.90.1200.10 89 276 6.2E-21 T 28-03-2018 CNX65_RS04315 bbb104fd0692bfae7401857d258d7c19 285 Pfam PF03881 Fructosamine kinase 53 277 1.2E-37 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CNX65_RS04315 bbb104fd0692bfae7401857d258d7c19 285 SUPERFAMILY SSF56112 30 273 1.6E-38 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS04315 bbb104fd0692bfae7401857d258d7c19 285 PIRSF PIRSF006221 31 283 2.4E-51 T 28-03-2018 IPR016477 Fructosamine/Ketosamine-3-kinase Reactome: R-HSA-163841 CNX65_RS13050 9f67ed8298895c8c8103947401938bfb 274 Gene3D G3DSA:1.10.3720.10 1 271 6.3E-40 T 28-03-2018 CNX65_RS13050 9f67ed8298895c8c8103947401938bfb 274 SUPERFAMILY SSF161098 35 264 4.84E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS13050 9f67ed8298895c8c8103947401938bfb 274 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 266 1.6E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS26080 bb0ef6db527144e5d4ff631e6231b93f 272 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 90 103 - T 28-03-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26080 bb0ef6db527144e5d4ff631e6231b93f 272 Hamap MF_01215 Orotidine 5'-phosphate decarboxylase [pyrF]. 2 272 32.621 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS26080 bb0ef6db527144e5d4ff631e6231b93f 272 SUPERFAMILY SSF51366 3 262 2.59E-57 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS26080 bb0ef6db527144e5d4ff631e6231b93f 272 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 16 235 3.4E-34 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26080 bb0ef6db527144e5d4ff631e6231b93f 272 SMART SM00934 16 262 1.0E-29 T 28-03-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 CNX65_RS26080 bb0ef6db527144e5d4ff631e6231b93f 272 Gene3D G3DSA:3.20.20.70 2 271 3.9E-79 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS26080 bb0ef6db527144e5d4ff631e6231b93f 272 TIGRFAM TIGR02127 pyrF_sub2: orotidine 5'-phosphate decarboxylase 3 260 1.7E-82 T 28-03-2018 IPR011995 Orotidine 5'-phosphate decarboxylase, type 2 GO:0004590|GO:0006221 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 CNX65_RS21860 77cc245abff0c4bd407caaf554f33be4 195 SUPERFAMILY SSF46689 3 65 7.18E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21860 77cc245abff0c4bd407caaf554f33be4 195 Gene3D G3DSA:1.10.357.10 120 195 0.098 T 28-03-2018 CNX65_RS21860 77cc245abff0c4bd407caaf554f33be4 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 2.9E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21860 77cc245abff0c4bd407caaf554f33be4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21860 77cc245abff0c4bd407caaf554f33be4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21860 77cc245abff0c4bd407caaf554f33be4 195 Gene3D G3DSA:1.10.10.60 2 48 1.3E-17 T 28-03-2018 CNX65_RS21860 77cc245abff0c4bd407caaf554f33be4 195 Gene3D G3DSA:1.10.357.10 49 119 4.1E-6 T 28-03-2018 CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 87 98 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 183 200 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 3.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 Gene3D G3DSA:3.40.50.720 192 245 0.052 T 28-03-2018 CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 Pfam PF00106 short chain dehydrogenase 13 206 1.2E-49 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 Gene3D G3DSA:3.40.50.720 7 191 1.3E-54 T 28-03-2018 CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 SUPERFAMILY SSF51735 9 272 3.56E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 87 98 1.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 1.6E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19530 465aafd47bf2b60aaa6eb44949c6eaa3 284 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 147 175 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 SUPERFAMILY SSF52821 149 279 1.7E-29 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 Pfam PF00581 Rhodanese-like domain 13 126 9.9E-18 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 Pfam PF00581 Rhodanese-like domain 161 270 1.6E-9 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 Gene3D G3DSA:3.40.250.10 1 146 2.0E-33 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 SUPERFAMILY SSF52821 2 146 1.01E-36 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 SMART SM00450 6 130 4.2E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 SMART SM00450 151 274 5.7E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS07270 96a4635a933f0f67c0a285fe60ca97ea 282 Gene3D G3DSA:3.40.250.10 147 282 8.7E-24 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS13920 75e596e98dc365561856bb3463f9431b 360 Pfam PF12698 ABC-2 family transporter protein 24 334 1.1E-24 T 28-03-2018 CNX65_RS09680 a03fef7adc636946cfa4535581fcefc9 250 SUPERFAMILY SSF55874 163 236 4.73E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09680 a03fef7adc636946cfa4535581fcefc9 250 Pfam PF07730 Histidine kinase 65 132 3.7E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS09680 a03fef7adc636946cfa4535581fcefc9 250 Gene3D G3DSA:3.30.565.10 131 245 5.9E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11010 bf47816690d7c87c8654b2cdca5d407b 359 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 142 317 4.5E-49 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CNX65_RS11010 bf47816690d7c87c8654b2cdca5d407b 359 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 11 289 1.1E-52 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11010 bf47816690d7c87c8654b2cdca5d407b 359 Pfam PF02470 MlaD protein 37 111 4.0E-12 T 28-03-2018 IPR003399 Mce/MlaD CNX65_RS03805 e38f1339241b7d5f12b3bb0985a35f73 363 Pfam PF00155 Aminotransferase class I and II 29 361 1.5E-44 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS03805 e38f1339241b7d5f12b3bb0985a35f73 363 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 219 232 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CNX65_RS03805 e38f1339241b7d5f12b3bb0985a35f73 363 Gene3D G3DSA:3.40.640.10 63 266 2.2E-36 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS03805 e38f1339241b7d5f12b3bb0985a35f73 363 Gene3D G3DSA:3.90.1150.10 267 363 5.2E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS03805 e38f1339241b7d5f12b3bb0985a35f73 363 TIGRFAM TIGR03539 DapC_actino: succinyldiaminopimelate transaminase 7 361 3.7E-173 T 28-03-2018 IPR019880 Succinyldiaminopimelate transaminase, DapC, actinobacteria CNX65_RS03805 e38f1339241b7d5f12b3bb0985a35f73 363 SUPERFAMILY SSF53383 20 362 2.78E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 SUPERFAMILY SSF51556 57 110 9.21E-32 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 SUPERFAMILY SSF51556 180 479 9.21E-32 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 Gene3D G3DSA:2.30.40.10 463 522 1.0E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 Gene3D G3DSA:3.20.20.140 164 462 4.9E-48 T 28-03-2018 CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 Pfam PF07969 Amidohydrolase family 46 517 2.2E-80 T 28-03-2018 IPR013108 Amidohydrolase 3 CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 Gene3D G3DSA:2.30.40.10 6 105 3.7E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 SUPERFAMILY SSF51338 3 58 1.45E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS05505 888b383120ad49afe459ed0aea14d977 525 SUPERFAMILY SSF51338 478 518 1.45E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS29965 0e9d105db8c0dd1e31d17e55f0996b2b 339 Gene3D G3DSA:2.60.120.10 264 329 1.2E-7 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS29965 0e9d105db8c0dd1e31d17e55f0996b2b 339 SUPERFAMILY SSF51182 15 331 2.05E-49 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS29965 0e9d105db8c0dd1e31d17e55f0996b2b 339 Gene3D G3DSA:2.60.120.10 12 219 3.6E-32 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 SMART SM00487 38 453 6.1E-25 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Pfam PF02151 UvrB/uvrC motif 680 713 1.9E-6 T 28-03-2018 IPR001943 UVR domain GO:0005515 CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 SUPERFAMILY SSF52540 34 443 1.42E-130 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 SMART SM00490 488 574 7.3E-19 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Gene3D G3DSA:3.40.50.300 39 441 1.6E-32 T 28-03-2018 CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Pfam PF12344 Ultra-violet resistance protein B 580 621 6.8E-21 T 28-03-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Gene3D G3DSA:4.10.860.10 659 716 6.8E-13 T 28-03-2018 IPR001943 UVR domain GO:0005515 CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Hamap MF_00204 UvrABC system protein B [uvrB]. 32 713 42.741 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Pfam PF04851 Type III restriction enzyme, res subunit 43 157 4.6E-7 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 33 711 0.0 T 28-03-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006281|GO:0006289|GO:0009381|GO:0009432 CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 SUPERFAMILY SSF52540 487 608 1.36E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 SUPERFAMILY SSF52540 62 111 1.36E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Pfam PF00271 Helicase conserved C-terminal domain 464 572 8.4E-18 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 Gene3D G3DSA:3.40.50.300 443 617 6.6E-33 T 28-03-2018 CNX65_RS27470 f10a73849e9bcf31e981277551fa12b1 723 SUPERFAMILY SSF46600 669 715 6.15E-10 T 28-03-2018 IPR001943 UVR domain GO:0005515 CNX65_RS11695 61aa14d63b27629ebef7a5c36d361bd6 378 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 9 127 2.7E-23 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS11695 61aa14d63b27629ebef7a5c36d361bd6 378 SUPERFAMILY SSF51735 4 169 1.61E-47 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS11695 61aa14d63b27629ebef7a5c36d361bd6 378 Gene3D G3DSA:3.40.50.720 1 149 5.8E-37 T 28-03-2018 CNX65_RS11695 61aa14d63b27629ebef7a5c36d361bd6 378 Gene3D G3DSA:3.30.360.10 150 377 5.9E-55 T 28-03-2018 CNX65_RS11695 61aa14d63b27629ebef7a5c36d361bd6 378 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 149 271 5.1E-10 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS11695 61aa14d63b27629ebef7a5c36d361bd6 378 SUPERFAMILY SSF55347 143 301 3.43E-39 T 28-03-2018 CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 ProSitePatterns PS00211 ABC transporters family signature. 518 532 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 SUPERFAMILY SSF90123 30 350 6.67E-68 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 Pfam PF00005 ABC transporter 398 546 2.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 Gene3D G3DSA:1.20.1560.10 24 352 5.4E-60 T 28-03-2018 CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 SMART SM00382 406 598 2.2E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 SUPERFAMILY SSF52540 356 617 2.61E-80 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 Pfam PF00664 ABC transporter transmembrane region 46 314 1.6E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS26520 da17e595d8259e8c7754cfdf2591f9bc 632 Gene3D G3DSA:3.40.50.300 355 622 1.5E-70 T 28-03-2018 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 ProSitePatterns PS00622 LuxR-type HTH domain signature. 167 194 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 SUPERFAMILY SSF52172 1 133 2.85E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 Pfam PF00072 Response regulator receiver domain 4 114 3.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 Gene3D G3DSA:1.10.10.10 126 217 4.7E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 6.9E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 SMART SM00448 2 114 2.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 SMART SM00421 150 207 3.8E-28 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 Gene3D G3DSA:3.40.50.2300 1 125 7.2E-38 T 28-03-2018 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34635 6730d2e786e57ff8bd238a48cb028289 218 SUPERFAMILY SSF46894 146 214 4.08E-24 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS08000 a7b7c1d096c858147686bb5fb8dbb33c 393 Gene3D G3DSA:1.20.91.10 229 313 4.7E-7 T 28-03-2018 CNX65_RS08000 a7b7c1d096c858147686bb5fb8dbb33c 393 Pfam PF00999 Sodium/hydrogen exchanger family 14 371 6.4E-45 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CNX65_RS23255 84ee3b0ca32bb8828520d39832db1719 312 SUPERFAMILY SSF53474 34 308 8.18E-70 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23255 84ee3b0ca32bb8828520d39832db1719 312 Pfam PF07859 alpha/beta hydrolase fold 70 276 6.6E-70 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CNX65_RS23255 84ee3b0ca32bb8828520d39832db1719 312 Gene3D G3DSA:3.40.50.1820 6 303 5.3E-58 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02485 bda25b0219c6edfebb2192c05b5c425c 479 Pfam PF00860 Permease family 20 432 2.7E-30 T 28-03-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS29035 6cb5dd72babf3f5348ed46f3e8aa0c22 117 Pfam PF02021 Uncharacterised protein family UPF0102 11 100 5.0E-23 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CNX65_RS29035 6cb5dd72babf3f5348ed46f3e8aa0c22 117 Gene3D G3DSA:3.40.1350.10 10 117 6.8E-29 T 28-03-2018 CNX65_RS29035 6cb5dd72babf3f5348ed46f3e8aa0c22 117 SUPERFAMILY SSF52980 5 111 3.43E-18 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CNX65_RS29035 6cb5dd72babf3f5348ed46f3e8aa0c22 117 Hamap MF_00048 UPF0102 protein YraN [yraN]. 4 114 18.337 T 28-03-2018 IPR003509 Uncharacterised protein family UPF0102 CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 SUPERFAMILY SSF53850 99 260 2.9E-16 T 28-03-2018 CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 Pfam PF03466 LysR substrate binding domain 101 260 1.1E-13 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 Gene3D G3DSA:1.10.10.10 1 82 7.7E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 9.3E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 Gene3D G3DSA:3.40.190.10 167 256 1.3E-11 T 28-03-2018 CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 SUPERFAMILY SSF46785 2 81 2.13E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30595 6f2e02938d4e518b70c01437aa4f7ede 279 Gene3D G3DSA:3.40.190.10 83 166 3.1E-9 T 28-03-2018 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 Pfam PF13188 PAS domain 314 350 3.0E-4 T 28-03-2018 IPR000014 PAS domain CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 Gene3D G3DSA:3.30.450.20 294 424 5.0E-11 T 28-03-2018 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 SMART SM00387 542 655 2.0E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 Gene3D G3DSA:1.10.287.130 425 493 6.0E-7 T 28-03-2018 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 PRINTS PR00344 Bacterial sensor protein C-terminal signature 615 633 4.5E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 PRINTS PR00344 Bacterial sensor protein C-terminal signature 639 652 4.5E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 PRINTS PR00344 Bacterial sensor protein C-terminal signature 582 596 4.5E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 PRINTS PR00344 Bacterial sensor protein C-terminal signature 600 610 4.5E-16 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 Gene3D G3DSA:3.30.565.10 500 655 3.1E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 Pfam PF05231 MASE1 5 287 9.1E-10 T 28-03-2018 IPR007895 MASE1 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 SUPERFAMILY SSF55785 299 418 6.28E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 543 653 2.5E-27 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 SUPERFAMILY SSF55874 494 653 2.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 SUPERFAMILY SSF47384 412 493 5.89E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12115 043d5e1bcaf1d30ed7da2f4c30b3ff13 655 SMART SM00388 426 498 4.0E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS09735 00551f7a91f3539101afde06604e7970 259 SUPERFAMILY SSF161098 3 252 3.05E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09735 00551f7a91f3539101afde06604e7970 259 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 50 253 1.2E-72 T 28-03-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 CNX65_RS09735 00551f7a91f3539101afde06604e7970 259 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 67 257 1.6E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09735 00551f7a91f3539101afde06604e7970 259 Gene3D G3DSA:1.10.3720.10 6 257 1.2E-42 T 28-03-2018 CNX65_RS09735 00551f7a91f3539101afde06604e7970 259 TIGRFAM TIGR01581 Mo_ABC_porter: NifC-like ABC-type porter 27 249 1.3E-72 T 28-03-2018 IPR006469 NifC-like ABC-type porter GO:0005215|GO:0006810|GO:0016020 CNX65_RS28750 41ab16e50f4c65a0b85830da5a460def 204 SUPERFAMILY SSF52540 12 204 5.31E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28750 41ab16e50f4c65a0b85830da5a460def 204 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 19 204 9.3E-74 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CNX65_RS28750 41ab16e50f4c65a0b85830da5a460def 204 Gene3D G3DSA:3.40.50.300 5 204 1.6E-60 T 28-03-2018 CNX65_RS28750 41ab16e50f4c65a0b85830da5a460def 204 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 22 204 3.1E-56 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CNX65_RS28750 41ab16e50f4c65a0b85830da5a460def 204 PIRSF PIRSF015617 1 204 1.5E-62 T 28-03-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6268|MetaCyc: PWY-6269 CNX65_RS16820 a9225a27d4d7a408d6aaaddae5d197c5 463 Pfam PF00135 Carboxylesterase family 338 434 7.6E-5 T 28-03-2018 IPR002018 Carboxylesterase, type B CNX65_RS16820 a9225a27d4d7a408d6aaaddae5d197c5 463 Pfam PF00135 Carboxylesterase family 13 328 5.1E-69 T 28-03-2018 IPR002018 Carboxylesterase, type B CNX65_RS16820 a9225a27d4d7a408d6aaaddae5d197c5 463 Gene3D G3DSA:3.40.50.1820 333 455 2.8E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16820 a9225a27d4d7a408d6aaaddae5d197c5 463 Gene3D G3DSA:3.40.50.1820 9 332 3.2E-79 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16820 a9225a27d4d7a408d6aaaddae5d197c5 463 SUPERFAMILY SSF53474 13 448 1.2E-87 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16820 a9225a27d4d7a408d6aaaddae5d197c5 463 ProSitePatterns PS01173 Lipolytic enzymes "G-D-X-G" family, putative histidine active site. 115 131 - T 28-03-2018 IPR002168 Lipase, GDXG, putative histidine active site GO:0008152|GO:0016787 Reactome: R-HSA-163560 CNX65_RS16820 a9225a27d4d7a408d6aaaddae5d197c5 463 ProSitePatterns PS00122 Carboxylesterases type-B serine active site. 186 201 - T 28-03-2018 IPR019826 Carboxylesterase type B, active site CNX65_RS11190 58a2f05f446c4dab9cded66ded748049 464 SUPERFAMILY SSF88946 22 99 4.71E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11190 58a2f05f446c4dab9cded66ded748049 464 Pfam PF04542 Sigma-70 region 2 38 98 6.8E-6 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11190 58a2f05f446c4dab9cded66ded748049 464 Gene3D G3DSA:1.10.1740.10 17 111 8.7E-11 T 28-03-2018 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 Pfam PF00012 Hsp70 protein 94 349 5.0E-29 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 PRINTS PR00301 70kDa heat shock protein signature 337 357 3.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 PRINTS PR00301 70kDa heat shock protein signature 306 322 3.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 PRINTS PR00301 70kDa heat shock protein signature 174 184 3.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 PRINTS PR00301 70kDa heat shock protein signature 3 16 3.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 PRINTS PR00301 70kDa heat shock protein signature 54 62 3.9E-9 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 TIGRFAM TIGR03931 T7SS_Rv3446c: type VII secretion-associated protein, Rv3446c family 476 651 1.1E-22 T 28-03-2018 IPR023840 Type VII secretion system Rv3446c CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 168 181 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 SUPERFAMILY SSF53067 4 153 1.26E-21 T 28-03-2018 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 Gene3D G3DSA:3.30.420.40 2 171 2.4E-29 T 28-03-2018 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 SUPERFAMILY SSF53067 165 350 8.87E-32 T 28-03-2018 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 Gene3D G3DSA:3.30.420.40 172 333 5.0E-25 T 28-03-2018 CNX65_RS32235 e990346b42ee55f0fd1ea922ab93d344 653 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 309 323 - T 28-03-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 CNX65_RS17190 3397e05114329bb6eb735888973da35a 845 SUPERFAMILY SSF144091 37 218 7.85E-9 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS17190 3397e05114329bb6eb735888973da35a 845 Gene3D G3DSA:3.40.630.30 579 807 1.4E-6 T 28-03-2018 CNX65_RS17190 3397e05114329bb6eb735888973da35a 845 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 514 810 3.8E-88 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CNX65_RS17190 3397e05114329bb6eb735888973da35a 845 Gene3D G3DSA:1.20.1540.10 35 254 2.3E-11 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS01065 2b3e697407e52538879a1cc4636ea27a 604 Gene3D G3DSA:3.40.50.1820 341 604 1.6E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS01065 2b3e697407e52538879a1cc4636ea27a 604 Pfam PF00326 Prolyl oligopeptidase family 397 603 6.0E-44 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS01065 2b3e697407e52538879a1cc4636ea27a 604 Gene3D G3DSA:2.130.10.150 33 131 2.0E-8 T 28-03-2018 CNX65_RS01065 2b3e697407e52538879a1cc4636ea27a 604 Gene3D G3DSA:2.140.10.30 164 340 6.8E-15 T 28-03-2018 CNX65_RS01065 2b3e697407e52538879a1cc4636ea27a 604 SUPERFAMILY SSF53474 363 603 2.89E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS01065 2b3e697407e52538879a1cc4636ea27a 604 SUPERFAMILY SSF82171 33 342 5.1E-22 T 28-03-2018 CNX65_RS28770 59746576ba0b18a040dbceaf3e6b2db0 392 SUPERFAMILY SSF53383 15 382 4.34E-94 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS28770 59746576ba0b18a040dbceaf3e6b2db0 392 Gene3D G3DSA:3.40.640.10 54 279 2.2E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS28770 59746576ba0b18a040dbceaf3e6b2db0 392 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 233 242 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CNX65_RS28770 59746576ba0b18a040dbceaf3e6b2db0 392 Gene3D G3DSA:3.90.1150.10 280 388 3.4E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS28770 59746576ba0b18a040dbceaf3e6b2db0 392 Pfam PF00155 Aminotransferase class I and II 39 378 8.4E-59 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS11295 1f3daed158c9b2b24edc06166af40771 87 SUPERFAMILY SSF101386 2 87 2.8E-21 T 28-03-2018 CNX65_RS11295 1f3daed158c9b2b24edc06166af40771 87 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 5 87 4.2E-23 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CNX65_RS11295 1f3daed158c9b2b24edc06166af40771 87 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 9 86 3.5E-7 T 28-03-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 CNX65_RS11295 1f3daed158c9b2b24edc06166af40771 87 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 1 87 18.344 T 28-03-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 CNX65_RS11295 1f3daed158c9b2b24edc06166af40771 87 Gene3D G3DSA:1.10.287.1080 1 87 8.1E-16 T 28-03-2018 CNX65_RS07175 a06a0d4fa240a3ecf7018b1d3ca0d70b 251 SUPERFAMILY SSF52540 10 244 9.04E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07175 a06a0d4fa240a3ecf7018b1d3ca0d70b 251 Gene3D G3DSA:3.40.50.300 7 250 1.6E-73 T 28-03-2018 CNX65_RS07175 a06a0d4fa240a3ecf7018b1d3ca0d70b 251 PIRSF PIRSF039085 7 250 4.8E-110 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CNX65_RS07175 a06a0d4fa240a3ecf7018b1d3ca0d70b 251 SMART SM00382 35 222 4.4E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS07175 a06a0d4fa240a3ecf7018b1d3ca0d70b 251 Pfam PF00005 ABC transporter 26 174 1.9E-35 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS07175 a06a0d4fa240a3ecf7018b1d3ca0d70b 251 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS24500 74617ee81602bfbc3f94c62668320a6f 196 Pfam PF13489 Methyltransferase domain 33 140 6.3E-12 T 28-03-2018 CNX65_RS24500 74617ee81602bfbc3f94c62668320a6f 196 SUPERFAMILY SSF53335 2 178 3.94E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS24500 74617ee81602bfbc3f94c62668320a6f 196 Gene3D G3DSA:3.40.50.150 23 194 3.5E-23 T 28-03-2018 CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 Pfam PF00005 ABC transporter 21 162 2.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 Gene3D G3DSA:3.40.50.300 2 237 6.5E-73 T 28-03-2018 CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 SUPERFAMILY SSF52540 4 243 2.0E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 Gene3D G3DSA:2.40.50.140 293 374 5.6E-14 T 28-03-2018 CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 SUPERFAMILY SSF50331 237 390 9.07E-18 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 SMART SM00382 29 212 4.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS04005 cef06c51a60ff90a1577e9d5a42339eb 394 Gene3D G3DSA:2.40.50.100 240 292 1.4E-13 T 28-03-2018 CNX65_RS26530 89cd3095dd8305442856c503a0e594c5 455 Gene3D G3DSA:1.10.10.60 297 370 1.6E-4 T 28-03-2018 CNX65_RS26530 89cd3095dd8305442856c503a0e594c5 455 Pfam PF13556 PucR C-terminal helix-turn-helix domain 336 392 1.1E-17 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS06605 71a72e4c6c7089cbfa08ead0f4f70156 685 Pfam PF07510 Protein of unknown function (DUF1524) 411 552 1.3E-24 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CNX65_RS06605 71a72e4c6c7089cbfa08ead0f4f70156 685 Pfam PF03235 Protein of unknown function DUF262 11 227 1.1E-34 T 28-03-2018 IPR004919 Domain of unknown function DUF262 CNX65_RS06605 71a72e4c6c7089cbfa08ead0f4f70156 685 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 576 651 7.0E-6 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS06605 71a72e4c6c7089cbfa08ead0f4f70156 685 SUPERFAMILY SSF46767 574 651 1.31E-6 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS06605 71a72e4c6c7089cbfa08ead0f4f70156 685 Gene3D G3DSA:1.10.10.10 570 671 4.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08770 52c6395ae319c470cd8678d57a46088a 149 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 3 140 7.4E-11 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CNX65_RS08770 52c6395ae319c470cd8678d57a46088a 149 Gene3D G3DSA:3.30.530.20 1 148 2.8E-17 T 28-03-2018 IPR023393 START-like domain CNX65_RS08770 52c6395ae319c470cd8678d57a46088a 149 SUPERFAMILY SSF55961 2 141 6.81E-18 T 28-03-2018 CNX65_RS16890 b70d9bc2a33998845fa298bf3edfa1bb 379 Gene3D G3DSA:3.90.180.10 8 167 5.4E-45 T 28-03-2018 CNX65_RS16890 b70d9bc2a33998845fa298bf3edfa1bb 379 Gene3D G3DSA:3.40.50.720 168 347 2.9E-25 T 28-03-2018 CNX65_RS16890 b70d9bc2a33998845fa298bf3edfa1bb 379 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 35 143 7.7E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS16890 b70d9bc2a33998845fa298bf3edfa1bb 379 SUPERFAMILY SSF51735 195 341 4.93E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16890 b70d9bc2a33998845fa298bf3edfa1bb 379 SMART SM00829 14 372 0.0082 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS16890 b70d9bc2a33998845fa298bf3edfa1bb 379 SUPERFAMILY SSF50129 6 169 8.83E-46 T 28-03-2018 IPR011032 GroES-like CNX65_RS16890 b70d9bc2a33998845fa298bf3edfa1bb 379 Pfam PF00107 Zinc-binding dehydrogenase 208 333 2.2E-17 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 Pfam PF13527 Acetyltransferase (GNAT) domain 6 127 3.1E-24 T 28-03-2018 CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 Gene3D G3DSA:3.40.630.30 1 129 3.2E-10 T 28-03-2018 CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 SUPERFAMILY SSF55718 293 398 2.55E-22 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 Gene3D G3DSA:3.30.1050.10 287 392 6.7E-28 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 Pfam PF13530 Sterol carrier protein domain 175 394 1.3E-47 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 Hamap MF_01812 UPF0256 protein . 2 398 31.9 T 28-03-2018 IPR022902 N-acetyltransferase Eis CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 SUPERFAMILY SSF55729 9 292 1.83E-47 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS05720 e428484e5e0bc26d475ba15435e68653 398 Gene3D G3DSA:3.40.630.30 130 286 2.8E-34 T 28-03-2018 CNX65_RS13485 6ad62bd6510868c7898077400887107b 542 SUPERFAMILY SSF52374 6 140 1.77E-49 T 28-03-2018 CNX65_RS13485 6ad62bd6510868c7898077400887107b 542 SUPERFAMILY SSF52374 175 385 1.77E-49 T 28-03-2018 CNX65_RS13485 6ad62bd6510868c7898077400887107b 542 Gene3D G3DSA:1.10.730.10 324 502 4.1E-12 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS13485 6ad62bd6510868c7898077400887107b 542 Pfam PF09334 tRNA synthetases class I (M) 8 397 5.3E-63 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS13485 6ad62bd6510868c7898077400887107b 542 Gene3D G3DSA:3.40.50.620 2 293 1.4E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS09925 876004beb15becbf46b81cc58ef298f9 181 SUPERFAMILY SSF48498 81 181 9.93E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS09925 876004beb15becbf46b81cc58ef298f9 181 Gene3D G3DSA:1.10.357.10 1 181 8.1E-33 T 28-03-2018 CNX65_RS09925 876004beb15becbf46b81cc58ef298f9 181 SUPERFAMILY SSF46689 6 77 3.45E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS09925 876004beb15becbf46b81cc58ef298f9 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 60 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22355 91d805084efcf28a25303cd54662a71c 423 Gene3D G3DSA:1.20.1250.20 214 412 5.9E-15 T 28-03-2018 CNX65_RS22355 91d805084efcf28a25303cd54662a71c 423 Pfam PF05977 Transmembrane secretion effector 8 415 1.1E-34 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS22355 91d805084efcf28a25303cd54662a71c 423 SUPERFAMILY SSF103473 9 412 9.02E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS22355 91d805084efcf28a25303cd54662a71c 423 Gene3D G3DSA:1.20.1250.20 2 202 2.5E-16 T 28-03-2018 CNX65_RS08250 ceac764fd744390f50b928e86cf64c44 263 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 24 240 8.0E-32 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS08250 ceac764fd744390f50b928e86cf64c44 263 SMART SM00062 21 244 1.8E-22 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS08250 ceac764fd744390f50b928e86cf64c44 263 Gene3D G3DSA:3.40.190.10 20 138 3.2E-19 T 28-03-2018 CNX65_RS08250 ceac764fd744390f50b928e86cf64c44 263 SUPERFAMILY SSF53850 20 243 6.63E-34 T 28-03-2018 CNX65_RS08250 ceac764fd744390f50b928e86cf64c44 263 Gene3D G3DSA:3.40.190.10 139 202 7.9E-9 T 28-03-2018 CNX65_RS25955 a3483354235474ec28336b93967b66a4 158 Pfam PF10756 Bacterial PH domain 81 151 2.0E-20 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CNX65_RS25555 790e57ca86f979a847bf38699b20854a 522 Pfam PF01966 HD domain 64 129 1.1E-9 T 28-03-2018 IPR006674 HD domain CNX65_RS25555 790e57ca86f979a847bf38699b20854a 522 Gene3D G3DSA:1.10.3210.10 2 225 1.1E-43 T 28-03-2018 CNX65_RS25555 790e57ca86f979a847bf38699b20854a 522 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 27 508 5.1E-59 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CNX65_RS25555 790e57ca86f979a847bf38699b20854a 522 SMART SM00471 60 262 1.0E-11 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS25555 790e57ca86f979a847bf38699b20854a 522 Gene3D G3DSA:1.10.3410.10 241 462 5.4E-14 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CNX65_RS25555 790e57ca86f979a847bf38699b20854a 522 SUPERFAMILY SSF109604 230 275 1.57E-47 T 28-03-2018 CNX65_RS25555 790e57ca86f979a847bf38699b20854a 522 SUPERFAMILY SSF109604 27 178 1.57E-47 T 28-03-2018 CNX65_RS05250 d1efe091417d636d6a58bb5c3cdd8900 377 Pfam PF04434 SWIM zinc finger 247 269 8.6E-5 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 2 397 1.2E-220 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Gene3D G3DSA:2.40.30.10 303 396 6.4E-34 T 28-03-2018 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Pfam PF03143 Elongation factor Tu C-terminal domain 302 395 6.5E-34 T 28-03-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 147 3.3E-13 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Gene3D G3DSA:2.40.30.10 208 299 1.4E-31 T 28-03-2018 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Pfam PF03144 Elongation factor Tu domain 2 227 296 1.1E-18 T 28-03-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 397 59.296 T 28-03-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 SUPERFAMILY SSF50465 305 397 1.04E-36 T 28-03-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Pfam PF00009 Elongation factor Tu GTP binding domain 10 203 2.3E-56 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 53 68 - T 28-03-2018 IPR031157 Tr-type G domain, conserved site CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Gene3D G3DSA:3.40.50.300 2 76 1.6E-11 T 28-03-2018 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 SUPERFAMILY SSF52540 9 228 3.64E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 Gene3D G3DSA:3.40.50.300 77 205 3.1E-31 T 28-03-2018 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 PRINTS PR00315 GTP-binding elongation factor signature 133 142 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 PRINTS PR00315 GTP-binding elongation factor signature 60 68 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 PRINTS PR00315 GTP-binding elongation factor signature 96 107 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 PRINTS PR00315 GTP-binding elongation factor signature 14 27 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 PRINTS PR00315 GTP-binding elongation factor signature 80 90 2.3E-24 T 28-03-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 CNX65_RS32460 96abdcd957c12e27fa3118b145e6980a 397 SUPERFAMILY SSF50447 207 304 3.95E-30 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS34520 97c7f91a70a90ca25c86093b1eb8aefa 271 SMART SM00079 47 266 0.001 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CNX65_RS34520 97c7f91a70a90ca25c86093b1eb8aefa 271 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 48 266 9.2E-61 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS34520 97c7f91a70a90ca25c86093b1eb8aefa 271 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 68 81 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CNX65_RS34520 97c7f91a70a90ca25c86093b1eb8aefa 271 Gene3D G3DSA:3.40.190.10 169 271 2.3E-17 T 28-03-2018 CNX65_RS34520 97c7f91a70a90ca25c86093b1eb8aefa 271 Gene3D G3DSA:3.40.190.10 8 168 3.3E-34 T 28-03-2018 CNX65_RS34520 97c7f91a70a90ca25c86093b1eb8aefa 271 SUPERFAMILY SSF53850 12 267 6.44E-62 T 28-03-2018 CNX65_RS34520 97c7f91a70a90ca25c86093b1eb8aefa 271 SMART SM00062 46 267 1.8E-62 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS33740 37c11f0d92e2228c0e7505eadffb6929 250 Gene3D G3DSA:1.10.10.10 110 225 3.1E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33740 37c11f0d92e2228c0e7505eadffb6929 250 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 219 3.5E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS33740 37c11f0d92e2228c0e7505eadffb6929 250 SMART SM00862 145 219 1.5E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS33740 37c11f0d92e2228c0e7505eadffb6929 250 SUPERFAMILY SSF46894 123 220 1.64E-30 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 SUPERFAMILY SSF55874 329 490 3.14E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 Pfam PF05227 CHASE3 domain 56 177 4.1E-19 T 28-03-2018 IPR007891 CHASE3 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 Pfam PF00672 HAMP domain 212 260 4.6E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 SMART SM00387 381 492 2.9E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 452 470 8.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 476 489 8.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 PRINTS PR00344 Bacterial sensor protein C-terminal signature 419 433 8.9E-13 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 Gene3D G3DSA:1.10.287.130 262 336 2.0E-13 T 28-03-2018 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 Gene3D G3DSA:3.30.565.10 340 492 2.3E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 384 490 4.2E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 SUPERFAMILY SSF158472 212 260 1.83E-5 T 28-03-2018 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 SMART SM00388 272 340 2.6E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 SMART SM00304 212 264 0.0014 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 Pfam PF00512 His Kinase A (phospho-acceptor) domain 273 337 8.2E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS24820 734bd3fefdc428f04c3a6fd44db76b04 498 SUPERFAMILY SSF47384 257 338 2.94E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 120 144 1.3E-6 T 28-03-2018 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 90 110 1.3E-6 T 28-03-2018 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 PRINTS PR01036 Tetracycline resistance protein TetB signature 325 345 1.3E-6 T 28-03-2018 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 ProSitePatterns PS00216 Sugar transport proteins signature 1. 50 67 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 Gene3D G3DSA:1.20.1250.20 241 454 7.1E-20 T 28-03-2018 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 Gene3D G3DSA:1.20.1250.20 1 186 1.2E-31 T 28-03-2018 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 Pfam PF07690 Major Facilitator Superfamily 2 400 6.7E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 SUPERFAMILY SSF103473 238 452 1.13E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19515 60aada2af0550f66bc754e9c4c62fa3a 455 SUPERFAMILY SSF103473 2 189 1.13E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 SUPERFAMILY SSF103039 38 210 5.75E-13 T 28-03-2018 IPR028976 CheC-like domain CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 Pfam PF02154 Flagellar motor switch protein FliM 30 214 4.8E-40 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 244 308 1.2E-12 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 SUPERFAMILY SSF101801 241 315 1.26E-11 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 Gene3D G3DSA:3.40.1550.10 39 224 3.2E-29 T 28-03-2018 IPR028976 CheC-like domain CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 Gene3D G3DSA:2.30.330.10 228 320 4.6E-15 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 PIRSF PIRSF002888 8 320 1.1E-74 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 PRINTS PR00955 Flagellar motor switch protein FliM signature 81 97 1.8E-6 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 PRINTS PR00955 Flagellar motor switch protein FliM signature 201 219 1.8E-6 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CNX65_RS11885 b736fdf30674eec6620b848d50441c8f 320 PRINTS PR00955 Flagellar motor switch protein FliM signature 106 125 1.8E-6 T 28-03-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 CNX65_RS09885 ae8dcf52081f87aa69eb90e3ec6a4df4 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 302 1.4E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09885 ae8dcf52081f87aa69eb90e3ec6a4df4 310 Gene3D G3DSA:1.10.3720.10 22 297 3.8E-35 T 28-03-2018 CNX65_RS09885 ae8dcf52081f87aa69eb90e3ec6a4df4 310 SUPERFAMILY SSF161098 28 309 6.54E-54 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS13005 b3cd72f61b53e4fe8bf710fb18147f3e 250 SUPERFAMILY SSF51126 38 211 3.38E-55 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS13005 b3cd72f61b53e4fe8bf710fb18147f3e 250 Gene3D G3DSA:2.160.20.10 37 249 5.8E-83 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS13005 b3cd72f61b53e4fe8bf710fb18147f3e 250 Pfam PF03211 Pectate lyase 24 225 1.0E-82 T 28-03-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 CNX65_RS05020 1f14dc2ce6e9f9315e44dd036807e5c4 390 Gene3D G3DSA:3.40.50.2000 1 207 2.3E-56 T 28-03-2018 CNX65_RS05020 1f14dc2ce6e9f9315e44dd036807e5c4 390 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 24 367 5.0E-93 T 28-03-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001 CNX65_RS05020 1f14dc2ce6e9f9315e44dd036807e5c4 390 Gene3D G3DSA:3.40.50.2000 208 343 1.3E-37 T 28-03-2018 CNX65_RS05020 1f14dc2ce6e9f9315e44dd036807e5c4 390 SUPERFAMILY SSF53756 1 370 6.28E-102 T 28-03-2018 CNX65_RS05020 1f14dc2ce6e9f9315e44dd036807e5c4 390 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 4 367 8.9E-106 T 28-03-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 Gene3D G3DSA:3.40.50.200 74 402 3.1E-67 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 350 360 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 Pfam PF00082 Subtilase family 137 374 9.4E-37 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 142 153 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 SUPERFAMILY SSF52743 125 401 1.57E-61 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 174 187 5.8E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 349 365 5.8E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS07995 2906439b3e57d636a48ed5b34767895d 402 PRINTS PR00723 Subtilisin serine protease family (S8) signature 137 156 5.8E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 56 98 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 Gene3D G3DSA:1.10.10.60 57 114 3.0E-14 T 28-03-2018 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 SUPERFAMILY SSF46689 55 103 3.4E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 86 102 1.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 71 86 1.4E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 SMART SM00342 19 102 7.9E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 SUPERFAMILY SSF46689 3 52 2.51E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 Gene3D G3DSA:2.60.40.1120 118 224 1.6E-4 T 28-03-2018 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 Pfam PF12833 Helix-turn-helix domain 31 103 9.0E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 SUPERFAMILY SSF117074 144 220 4.71E-7 T 28-03-2018 CNX65_RS20550 72c3aa2c9ffdf8fb4a22ee5add9aee3c 250 Gene3D G3DSA:1.10.10.60 2 56 3.9E-10 T 28-03-2018 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 177 5.7E-74 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 Pfam PF00347 Ribosomal protein L6 92 165 6.7E-20 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 Pfam PF00347 Ribosomal protein L6 11 83 7.4E-19 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 155 163 - T 28-03-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 Gene3D G3DSA:3.90.930.12 87 179 5.7E-39 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 SUPERFAMILY SSF56053 84 178 1.3E-34 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 177 38.565 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 PIRSF PIRSF002162 1 178 2.7E-47 T 28-03-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 Gene3D G3DSA:3.90.930.12 5 86 8.6E-29 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 PRINTS PR00059 Ribosomal protein L6 signature 142 163 1.3E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 PRINTS PR00059 Ribosomal protein L6 signature 72 97 1.3E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 PRINTS PR00059 Ribosomal protein L6 signature 100 116 1.3E-33 T 28-03-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 CNX65_RS32375 03b220b12b11306bb0b9bad819f39158 179 SUPERFAMILY SSF56053 1 83 4.84E-26 T 28-03-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS25280 b81bcfa543d38ab588fc3ed40d8458e2 265 SUPERFAMILY SSF100950 5 261 2.09E-69 T 28-03-2018 CNX65_RS25280 b81bcfa543d38ab588fc3ed40d8458e2 265 Pfam PF01144 Coenzyme A transferase 6 222 4.3E-20 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CNX65_RS25280 b81bcfa543d38ab588fc3ed40d8458e2 265 SMART SM00882 4 224 6.8E-37 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CNX65_RS25280 b81bcfa543d38ab588fc3ed40d8458e2 265 Gene3D G3DSA:3.40.1080.10 1 245 1.1E-50 T 28-03-2018 CNX65_RS32990 239cf5b198394c8cfa0d619f730ecc1f 348 Pfam PF03747 ADP-ribosylglycohydrolase 6 313 3.3E-66 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS32990 239cf5b198394c8cfa0d619f730ecc1f 348 Gene3D G3DSA:1.10.4080.10 3 338 8.5E-70 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS32990 239cf5b198394c8cfa0d619f730ecc1f 348 SUPERFAMILY SSF101478 118 327 4.97E-53 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS32990 239cf5b198394c8cfa0d619f730ecc1f 348 SUPERFAMILY SSF101478 4 90 4.97E-53 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 6.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 6.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 6.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 SUPERFAMILY SSF51735 4 235 2.01E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 Gene3D G3DSA:3.40.50.720 153 246 1.9E-15 T 28-03-2018 CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 148 1.0E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 1.0E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 169 188 1.0E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 Pfam PF00106 short chain dehydrogenase 6 208 4.6E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25485 3abef48a52a8689c27ae98d4f691d152 246 Gene3D G3DSA:3.40.50.720 2 152 8.5E-37 T 28-03-2018 CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 179 1.3E-57 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 SUPERFAMILY SSF54211 3 87 1.2E-30 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 SUPERFAMILY SSF54211 88 184 8.89E-29 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 Gene3D G3DSA:3.30.230.40 1 89 4.3E-32 T 28-03-2018 CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 200 40.759 T 28-03-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 161 173 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 Gene3D G3DSA:3.30.230.40 91 200 2.3E-35 T 28-03-2018 CNX65_RS28035 475f16d745a3f3c1f9e473a709a3e3f5 200 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 28-03-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 SUPERFAMILY SSF50346 10 86 4.4E-10 T 28-03-2018 IPR011033 PRC-barrel-like CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 Gene3D G3DSA:2.30.30.240 7 77 1.7E-10 T 28-03-2018 CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 SMART SM00116 356 404 0.0022 T 28-03-2018 IPR000644 CBS domain CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 Pfam PF03448 MgtE intracellular N domain 177 276 7.2E-25 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 SUPERFAMILY SSF54631 279 410 1.26E-24 T 28-03-2018 CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 Gene3D G3DSA:3.10.580.10 278 414 5.7E-18 T 28-03-2018 CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 SMART SM00924 177 280 1.7E-31 T 28-03-2018 IPR006668 Magnesium transporter, MgtE intracellular domain CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 Gene3D G3DSA:1.25.60.10 151 275 5.3E-22 T 28-03-2018 CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 Pfam PF00571 CBS domain 352 404 2.4E-5 T 28-03-2018 IPR000644 CBS domain CNX65_RS03965 2875cabdd4f19087dd1f054adfc696de 416 SUPERFAMILY SSF158791 165 275 1.31E-28 T 28-03-2018 CNX65_RS29450 df9e38369a753847aad26e05af369876 578 Pfam PF13655 N-terminal domain of reverse transcriptase 19 98 1.2E-24 T 28-03-2018 IPR025960 Reverse transcriptase, N-terminal domain CNX65_RS29450 df9e38369a753847aad26e05af369876 578 TIGRFAM TIGR04416 group_II_RT_mat: group II intron reverse transcriptase/maturase 66 420 5.6E-97 T 28-03-2018 IPR030931 Group II intron reverse transcriptase/maturase CNX65_RS29450 df9e38369a753847aad26e05af369876 578 SUPERFAMILY SSF56672 93 432 3.94E-50 T 28-03-2018 CNX65_RS29450 df9e38369a753847aad26e05af369876 578 Pfam PF00078 Reverse transcriptase (RNA-dependent DNA polymerase) 118 339 2.0E-40 T 28-03-2018 IPR000477 Reverse transcriptase domain CNX65_RS29450 df9e38369a753847aad26e05af369876 578 Pfam PF08388 Group II intron, maturase-specific domain 355 433 2.4E-22 T 28-03-2018 IPR013597 Group II intron, maturase-specific CNX65_RS29450 df9e38369a753847aad26e05af369876 578 Gene3D G3DSA:3.30.70.270 149 339 2.4E-25 T 28-03-2018 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 SUPERFAMILY SSF54373 369 497 6.67E-38 T 28-03-2018 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 Gene3D G3DSA:4.10.450.10 121 185 0.0032 T 28-03-2018 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 Gene3D G3DSA:3.30.410.10 324 489 1.6E-55 T 28-03-2018 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 Gene3D G3DSA:3.30.410.10 212 291 1.4E-15 T 28-03-2018 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 Pfam PF05199 GMC oxidoreductase 492 543 5.0E-12 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 Gene3D G3DSA:3.40.50.720 64 118 3.5E-4 T 28-03-2018 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 Pfam PF00890 FAD binding domain 66 95 6.3E-5 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 SUPERFAMILY SSF51905 284 371 2.78E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 SUPERFAMILY SSF51905 494 550 2.78E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS12320 d2aa31112e0a7300ee5b1517b38ffd20 553 SUPERFAMILY SSF51905 65 244 2.78E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24725 eedefd0c9018fad5c0983635b01802d2 493 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 339 489 9.8E-33 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS24725 eedefd0c9018fad5c0983635b01802d2 493 SUPERFAMILY SSF55073 348 491 7.38E-37 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS24725 eedefd0c9018fad5c0983635b01802d2 493 Gene3D G3DSA:3.30.70.270 333 493 6.1E-47 T 28-03-2018 CNX65_RS24725 eedefd0c9018fad5c0983635b01802d2 493 SMART SM00267 332 493 6.7E-46 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS24725 eedefd0c9018fad5c0983635b01802d2 493 Pfam PF00990 Diguanylate cyclase, GGDEF domain 343 487 7.5E-36 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS31580 87694a7c55ca03f382c1f5778b371c8f 218 Pfam PF08044 Domain of unknown function (DUF1707) 12 63 1.9E-22 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CNX65_RS31580 87694a7c55ca03f382c1f5778b371c8f 218 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 119 174 5.0E-10 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CNX65_RS13010 88cef4f6409e10057e32927d8469280a 312 Gene3D G3DSA:3.30.1780.10 9 141 1.1E-28 T 28-03-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 CNX65_RS13010 88cef4f6409e10057e32927d8469280a 312 Gene3D G3DSA:3.40.50.720 142 292 5.3E-24 T 28-03-2018 CNX65_RS13010 88cef4f6409e10057e32927d8469280a 312 PIRSF PIRSF001439 5 311 2.9E-63 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CNX65_RS13010 88cef4f6409e10057e32927d8469280a 312 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 26 301 5.6E-60 T 28-03-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 CNX65_RS13010 88cef4f6409e10057e32927d8469280a 312 SUPERFAMILY SSF51735 10 306 1.75E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 SMART SM00448 3 116 9.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 Gene3D G3DSA:1.10.10.10 135 211 7.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 SMART SM00421 150 207 1.5E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 Pfam PF00072 Response regulator receiver domain 6 116 1.9E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 SUPERFAMILY SSF52172 3 132 7.54E-29 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 4.4E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 SUPERFAMILY SSF46894 142 211 7.14E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 4.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 4.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 4.5E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08025 b6f05b6082789b3c6a86349e82112ce2 214 Gene3D G3DSA:3.40.50.2300 2 134 3.1E-31 T 28-03-2018 CNX65_RS34230 90e08d34d748ca038932c2f7adca23f6 224 Pfam PF09335 SNARE associated Golgi protein 43 170 2.6E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS31120 070c86aa637c52e0ebb21f55b3ec2e8b 358 Gene3D G3DSA:3.40.50.10490 12 192 2.2E-6 T 28-03-2018 CNX65_RS31120 070c86aa637c52e0ebb21f55b3ec2e8b 358 Gene3D G3DSA:3.40.50.10490 193 346 1.8E-25 T 28-03-2018 CNX65_RS31120 070c86aa637c52e0ebb21f55b3ec2e8b 358 Pfam PF10432 Bacterial phospho-glucose isomerase C-terminal SIS domain 200 346 3.0E-7 T 28-03-2018 IPR019490 Bifunctional glucose-6-phosphate/mannose-6-phosphate isomerase, C-terminal GO:0004347|GO:0004476|GO:0005975 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00051+5.3.1.8|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.8+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 CNX65_RS31120 070c86aa637c52e0ebb21f55b3ec2e8b 358 SUPERFAMILY SSF53697 64 346 5.34E-46 T 28-03-2018 CNX65_RS18175 8fbb421ad5c90c0c85a27896ec22bb19 271 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 13 202 1.9E-81 T 28-03-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 CNX65_RS18175 8fbb421ad5c90c0c85a27896ec22bb19 271 Pfam PF00005 ABC transporter 20 168 3.5E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18175 8fbb421ad5c90c0c85a27896ec22bb19 271 SMART SM00382 29 223 2.5E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18175 8fbb421ad5c90c0c85a27896ec22bb19 271 Gene3D G3DSA:3.40.50.300 1 238 2.9E-59 T 28-03-2018 CNX65_RS18175 8fbb421ad5c90c0c85a27896ec22bb19 271 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS18175 8fbb421ad5c90c0c85a27896ec22bb19 271 SUPERFAMILY SSF52540 3 228 3.26E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08480 bc8eacf0f37bcb240a53700cb9cf8ce3 281 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 130 278 6.7E-30 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS08480 bc8eacf0f37bcb240a53700cb9cf8ce3 281 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 208 223 5.9E-9 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS08480 bc8eacf0f37bcb240a53700cb9cf8ce3 281 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 223 235 5.9E-9 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS08480 bc8eacf0f37bcb240a53700cb9cf8ce3 281 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 141 156 5.9E-9 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS08480 bc8eacf0f37bcb240a53700cb9cf8ce3 281 Gene3D G3DSA:2.40.100.10 106 281 1.9E-48 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS08480 bc8eacf0f37bcb240a53700cb9cf8ce3 281 SUPERFAMILY SSF50891 128 278 1.23E-42 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS22555 dff59fa01fae30a13da5fed87d32658f 391 Pfam PF13186 Iron-sulfur cluster-binding domain 321 383 4.8E-10 T 28-03-2018 IPR023885 4Fe4S-binding SPASM domain CNX65_RS22555 dff59fa01fae30a13da5fed87d32658f 391 Gene3D G3DSA:3.20.20.70 35 372 9.1E-37 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS22555 dff59fa01fae30a13da5fed87d32658f 391 Pfam PF13394 4Fe-4S single cluster domain 52 124 9.3E-7 T 28-03-2018 CNX65_RS22555 dff59fa01fae30a13da5fed87d32658f 391 Pfam PF04055 Radical SAM superfamily 50 215 1.6E-12 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS22555 dff59fa01fae30a13da5fed87d32658f 391 SUPERFAMILY SSF102114 277 387 3.14E-45 T 28-03-2018 CNX65_RS22555 dff59fa01fae30a13da5fed87d32658f 391 SUPERFAMILY SSF102114 44 247 3.14E-45 T 28-03-2018 CNX65_RS13065 0fa8d196d6c1025b5f39f1b78f1341d9 512 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 290 502 6.8E-32 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS13065 0fa8d196d6c1025b5f39f1b78f1341d9 512 Gene3D G3DSA:3.20.20.80 17 376 6.2E-105 T 28-03-2018 CNX65_RS13065 0fa8d196d6c1025b5f39f1b78f1341d9 512 SUPERFAMILY SSF51445 17 383 5.06E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS13065 0fa8d196d6c1025b5f39f1b78f1341d9 512 SMART SM00813 290 502 2.6E-55 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS13065 0fa8d196d6c1025b5f39f1b78f1341d9 512 Gene3D G3DSA:2.60.40.1180 377 511 1.6E-29 T 28-03-2018 CNX65_RS13065 0fa8d196d6c1025b5f39f1b78f1341d9 512 SUPERFAMILY SSF51011 366 507 3.34E-21 T 28-03-2018 CNX65_RS00445 8eae7512024f6e965b25a12205419861 394 Gene3D G3DSA:2.60.120.10 62 365 2.2E-30 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS00445 8eae7512024f6e965b25a12205419861 394 Pfam PF04209 homogentisate 1,2-dioxygenase 116 374 1.1E-14 T 28-03-2018 IPR005708 Homogentisate 1,2-dioxygenase GO:0004411|GO:0006559|GO:0006570|GO:0055114 KEGG: 00350+1.13.11.5|KEGG: 00643+1.13.11.5|Reactome: R-HSA-71182 CNX65_RS00445 8eae7512024f6e965b25a12205419861 394 SUPERFAMILY SSF51182 6 388 2.74E-92 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS23245 6821f60e662f26a9e853e7b33cd29b52 244 SUPERFAMILY SSF55729 54 129 4.94E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS23245 6821f60e662f26a9e853e7b33cd29b52 244 Gene3D G3DSA:3.40.630.30 33 196 1.4E-8 T 28-03-2018 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00385 P450 superfamily signature 344 355 4.7E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00385 P450 superfamily signature 335 344 4.7E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00385 P450 superfamily signature 234 251 4.7E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00385 P450 superfamily signature 268 279 4.7E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 Gene3D G3DSA:1.10.630.10 8 400 7.3E-75 T 28-03-2018 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 SUPERFAMILY SSF48264 9 398 2.36E-94 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 Pfam PF00067 Cytochrome P450 268 365 1.8E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 Pfam PF00067 Cytochrome P450 181 261 5.2E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 286 313 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 344 355 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 135 151 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 268 279 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 335 344 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 188 210 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 152 167 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 89 100 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 PRINTS PR00359 B-class P450 signature 314 329 2.5E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21960 98943a9ee2e72a278c6c599a298071dd 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 SUPERFAMILY SSF47203 233 371 7.23E-9 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 PIRSF PIRSF016578 1 392 3.5E-109 T 28-03-2018 CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 Gene3D G3DSA:1.20.140.10 210 391 1.4E-10 T 28-03-2018 CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 241 370 7.4E-19 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 Gene3D G3DSA:1.10.540.10 1 121 1.8E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 18 85 1.5E-6 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 SUPERFAMILY SSF56645 8 208 6.54E-31 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS20485 2330221fe6db78a7e0fc6edd8bcacb74 392 Gene3D G3DSA:2.40.110.10 122 208 2.1E-14 T 28-03-2018 CNX65_RS04845 0d0c165f3b0fb689db7cab1b881ff949 852 SUPERFAMILY SSF52540 164 497 6.32E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04845 0d0c165f3b0fb689db7cab1b881ff949 852 Gene3D G3DSA:3.40.50.300 363 686 7.3E-28 T 28-03-2018 CNX65_RS04845 0d0c165f3b0fb689db7cab1b881ff949 852 Pfam PF00270 DEAD/DEAH box helicase 158 335 1.1E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS04845 0d0c165f3b0fb689db7cab1b881ff949 852 Pfam PF00271 Helicase conserved C-terminal domain 386 486 1.5E-9 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04845 0d0c165f3b0fb689db7cab1b881ff949 852 SMART SM00490 401 487 2.0E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04845 0d0c165f3b0fb689db7cab1b881ff949 852 SMART SM00487 142 357 2.9E-14 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS04845 0d0c165f3b0fb689db7cab1b881ff949 852 Gene3D G3DSA:3.40.50.300 105 362 3.5E-23 T 28-03-2018 CNX65_RS25595 e73bfc22f179f8aeaf44005bf8ab517c 373 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 23 295 1.2E-48 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS25595 e73bfc22f179f8aeaf44005bf8ab517c 373 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 21 299 9.4E-83 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS25595 e73bfc22f179f8aeaf44005bf8ab517c 373 SUPERFAMILY SSF55931 19 370 9.02E-90 T 28-03-2018 CNX65_RS25595 e73bfc22f179f8aeaf44005bf8ab517c 373 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 373 77.273 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 176 349 3.5E-37 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 Pfam PF01471 Putative peptidoglycan binding domain 10 66 7.2E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 Pfam PF01471 Putative peptidoglycan binding domain 87 143 1.0E-16 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 Gene3D G3DSA:1.10.101.10 79 146 4.3E-20 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 SUPERFAMILY SSF47090 80 145 1.18E-18 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 Gene3D G3DSA:1.10.101.10 1 76 1.9E-17 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 Gene3D G3DSA:3.40.630.40 157 359 1.0E-46 T 28-03-2018 CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 SUPERFAMILY SSF47090 3 67 1.7E-13 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 SUPERFAMILY SSF53187 173 352 1.6E-41 T 28-03-2018 CNX65_RS35010 038b5363a4d1cff692fcd8b807ab6bc2 379 SMART SM00646 234 349 1.7E-27 T 28-03-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 CNX65_RS15145 44bcb0e66113456c0bc02927ea83e96d 801 Pfam PF02687 FtsX-like permease family 265 358 9.2E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS15145 44bcb0e66113456c0bc02927ea83e96d 801 Pfam PF02687 FtsX-like permease family 704 788 9.7E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS00525 f7f1daea1eae0f182ab91d81a3e9a62f 126 SMART SM00345 18 77 6.5E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS00525 f7f1daea1eae0f182ab91d81a3e9a62f 126 SUPERFAMILY SSF46785 7 79 1.37E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00525 f7f1daea1eae0f182ab91d81a3e9a62f 126 Gene3D G3DSA:1.10.10.10 1 79 3.5E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00525 f7f1daea1eae0f182ab91d81a3e9a62f 126 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 9.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS13235 00212cf90add4f020af179e642e871a4 289 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 56 267 3.8E-33 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CNX65_RS13235 00212cf90add4f020af179e642e871a4 289 SUPERFAMILY SSF53213 34 288 1.44E-71 T 28-03-2018 CNX65_RS13235 00212cf90add4f020af179e642e871a4 289 Gene3D G3DSA:3.40.830.10 21 289 1.2E-67 T 28-03-2018 CNX65_RS13235 00212cf90add4f020af179e642e871a4 289 PIRSF PIRSF006157 31 289 2.0E-68 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CNX65_RS13885 6a75e56143c54b17678737e2c9233559 430 Pfam PF07730 Histidine kinase 225 290 6.8E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS13885 6a75e56143c54b17678737e2c9233559 430 SMART SM00387 335 427 2.2E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13885 6a75e56143c54b17678737e2c9233559 430 SUPERFAMILY SSF55874 308 424 1.72E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS13885 6a75e56143c54b17678737e2c9233559 430 Gene3D G3DSA:3.30.565.10 301 429 3.1E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19215 386837e6b3b23a9bbc2e2b8d05bdb81b 272 SUPERFAMILY SSF53474 8 265 2.34E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19215 386837e6b3b23a9bbc2e2b8d05bdb81b 272 Pfam PF12697 Alpha/beta hydrolase family 20 257 2.3E-16 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS19215 386837e6b3b23a9bbc2e2b8d05bdb81b 272 Gene3D G3DSA:3.40.50.1820 6 270 3.3E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS10605 23f0ff460da19551ffa5a7acc30026fc 449 Pfam PF00120 Glutamine synthetase, catalytic domain 115 443 1.8E-104 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS10605 23f0ff460da19551ffa5a7acc30026fc 449 SUPERFAMILY SSF54368 3 113 2.09E-18 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS10605 23f0ff460da19551ffa5a7acc30026fc 449 SUPERFAMILY SSF55931 114 447 8.63E-105 T 28-03-2018 CNX65_RS10605 23f0ff460da19551ffa5a7acc30026fc 449 SMART SM01230 114 367 2.3E-106 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS10605 23f0ff460da19551ffa5a7acc30026fc 449 Gene3D G3DSA:3.10.20.70 10 110 1.8E-23 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS10605 23f0ff460da19551ffa5a7acc30026fc 449 Gene3D G3DSA:3.30.590.10 111 449 3.2E-105 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CNX65_RS14390 0a133a39ac57783ddea8cb924314cce9 279 Gene3D G3DSA:1.10.3720.10 8 276 1.4E-34 T 28-03-2018 CNX65_RS14390 0a133a39ac57783ddea8cb924314cce9 279 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 266 6.2E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14390 0a133a39ac57783ddea8cb924314cce9 279 SUPERFAMILY SSF161098 5 266 1.87E-43 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17885 912dc3cccf5bf7db7cf6c7de8cfe99ce 267 Pfam PF00440 Bacterial regulatory proteins, tetR family 39 83 2.7E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS17885 912dc3cccf5bf7db7cf6c7de8cfe99ce 267 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 99 212 9.0E-12 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CNX65_RS17885 912dc3cccf5bf7db7cf6c7de8cfe99ce 267 Gene3D G3DSA:1.10.260.40 61 103 1.2E-5 T 28-03-2018 CNX65_RS17885 912dc3cccf5bf7db7cf6c7de8cfe99ce 267 Gene3D G3DSA:1.10.10.60 7 60 3.1E-9 T 28-03-2018 CNX65_RS17885 912dc3cccf5bf7db7cf6c7de8cfe99ce 267 SUPERFAMILY SSF46689 28 94 9.23E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS17885 912dc3cccf5bf7db7cf6c7de8cfe99ce 267 SUPERFAMILY SSF48498 101 262 7.34E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS17885 912dc3cccf5bf7db7cf6c7de8cfe99ce 267 Gene3D G3DSA:1.10.357.10 104 265 5.0E-35 T 28-03-2018 CNX65_RS27710 3839a8c1f4efb4339d1d9f05429f78a4 693 SUPERFAMILY SSF53474 451 692 1.35E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27710 3839a8c1f4efb4339d1d9f05429f78a4 693 Gene3D G3DSA:3.40.50.1820 444 693 6.9E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27710 3839a8c1f4efb4339d1d9f05429f78a4 693 Gene3D G3DSA:2.140.10.30 6 443 9.7E-59 T 28-03-2018 CNX65_RS27710 3839a8c1f4efb4339d1d9f05429f78a4 693 SUPERFAMILY SSF82171 20 396 3.4E-33 T 28-03-2018 CNX65_RS27710 3839a8c1f4efb4339d1d9f05429f78a4 693 Pfam PF00326 Prolyl oligopeptidase family 495 692 1.9E-46 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS27710 3839a8c1f4efb4339d1d9f05429f78a4 693 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 109 399 7.5E-36 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 CNX65_RS27940 abd466e9cdc0b144d8f30960912893a3 261 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 48 61 - T 28-03-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS27940 abd466e9cdc0b144d8f30960912893a3 261 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 14 257 31.79 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS27940 abd466e9cdc0b144d8f30960912893a3 261 SUPERFAMILY SSF51366 2 245 4.0E-80 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS27940 abd466e9cdc0b144d8f30960912893a3 261 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 8 239 6.7E-63 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS27940 abd466e9cdc0b144d8f30960912893a3 261 Pfam PF00290 Tryptophan synthase alpha chain 8 239 1.2E-70 T 28-03-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS27940 abd466e9cdc0b144d8f30960912893a3 261 Gene3D G3DSA:3.20.20.70 2 259 5.0E-80 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS16255 78a9349d91c4b915912a1a3c22158f84 144 PIRSF PIRSF001399 1 143 6.3E-47 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS16255 78a9349d91c4b915912a1a3c22158f84 144 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 28-03-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS16255 78a9349d91c4b915912a1a3c22158f84 144 SUPERFAMILY SSF52304 3 142 1.23E-49 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS16255 78a9349d91c4b915912a1a3c22158f84 144 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 123 1.0E-48 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS16255 78a9349d91c4b915912a1a3c22158f84 144 Gene3D G3DSA:3.40.50.9100 2 143 2.6E-46 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS16255 78a9349d91c4b915912a1a3c22158f84 144 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 144 51.164 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS16255 78a9349d91c4b915912a1a3c22158f84 144 Pfam PF01220 Dehydroquinase class II 4 138 1.5E-44 T 28-03-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 Pfam PF13361 UvrD-like helicase C-terminal domain 894 962 8.4E-20 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 Pfam PF13361 UvrD-like helicase C-terminal domain 703 840 1.7E-6 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 SUPERFAMILY SSF89550 4 250 9.61E-18 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 Gene3D G3DSA:3.40.50.300 468 696 1.2E-54 T 28-03-2018 CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 SUPERFAMILY SSF52540 464 977 6.68E-115 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 Gene3D G3DSA:3.40.50.300 697 984 1.4E-42 T 28-03-2018 CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 Pfam PF13245 AAA domain 472 682 1.8E-44 T 28-03-2018 CNX65_RS03140 ae83471fa0c768c2f7bfd04d565711c3 997 Gene3D G3DSA:3.20.20.140 3 235 1.9E-7 T 28-03-2018 CNX65_RS12015 ad9bf01ddee0d94c0ef66ba3520fab4d 86 Hamap MF_00167 Carbon storage regulator [csrA]. 1 70 20.124 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CNX65_RS12015 ad9bf01ddee0d94c0ef66ba3520fab4d 86 Pfam PF02599 Global regulator protein family 1 50 9.7E-24 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CNX65_RS12015 ad9bf01ddee0d94c0ef66ba3520fab4d 86 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 61 7.6E-24 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CNX65_RS12015 ad9bf01ddee0d94c0ef66ba3520fab4d 86 SUPERFAMILY SSF117130 1 51 3.27E-18 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CNX65_RS12015 ad9bf01ddee0d94c0ef66ba3520fab4d 86 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 8.0E-14 T 28-03-2018 IPR003751 Carbon storage regulator GO:0003723|GO:0006109|GO:0006402 CNX65_RS13935 942a46a21fc9cc1b8119f99cbb517144 169 SUPERFAMILY SSF55781 34 161 1.53E-14 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS13935 942a46a21fc9cc1b8119f99cbb517144 169 Pfam PF13185 GAF domain 41 159 1.9E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS13935 942a46a21fc9cc1b8119f99cbb517144 169 Gene3D G3DSA:3.30.450.40 8 168 3.3E-18 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 7.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 208 7.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 7.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 7.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 189 7.9E-25 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 Gene3D G3DSA:3.40.50.720 2 152 8.0E-35 T 28-03-2018 CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 SUPERFAMILY SSF51735 4 240 5.97E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 Pfam PF00106 short chain dehydrogenase 6 209 9.5E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 Gene3D G3DSA:3.40.50.720 153 247 2.4E-16 T 28-03-2018 CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 2.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04220 922d20f8c1f50167da89ab5169ae3dce 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 170 189 2.9E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15245 c44c5b7936cbb86093d464a624b37d68 711 SUPERFAMILY SSF48371 423 508 1.89E-6 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS15245 c44c5b7936cbb86093d464a624b37d68 711 SUPERFAMILY SSF48371 574 706 1.89E-6 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS15245 c44c5b7936cbb86093d464a624b37d68 711 SUPERFAMILY SSF48371 293 375 1.89E-6 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS15245 c44c5b7936cbb86093d464a624b37d68 711 Gene3D G3DSA:1.25.10.10 38 709 1.7E-11 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS02320 7d7a9f8fcd9c4746c0858626adf3208b 333 Gene3D G3DSA:3.40.190.10 151 332 7.3E-27 T 28-03-2018 CNX65_RS02320 7d7a9f8fcd9c4746c0858626adf3208b 333 Pfam PF13379 NMT1-like family 39 266 2.4E-19 T 28-03-2018 CNX65_RS02320 7d7a9f8fcd9c4746c0858626adf3208b 333 Gene3D G3DSA:3.40.190.10 37 150 6.9E-7 T 28-03-2018 CNX65_RS02320 7d7a9f8fcd9c4746c0858626adf3208b 333 SUPERFAMILY SSF53850 40 266 1.01E-22 T 28-03-2018 CNX65_RS01275 9f8063336e0f055bfe532b16c6c29d7d 293 Gene3D G3DSA:3.40.50.10490 73 287 8.4E-42 T 28-03-2018 CNX65_RS01275 9f8063336e0f055bfe532b16c6c29d7d 293 SUPERFAMILY SSF53697 97 275 2.37E-42 T 28-03-2018 CNX65_RS01275 9f8063336e0f055bfe532b16c6c29d7d 293 Gene3D G3DSA:1.10.10.10 1 72 4.3E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01275 9f8063336e0f055bfe532b16c6c29d7d 293 Pfam PF01418 Helix-turn-helix domain, rpiR family 2 71 7.5E-19 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CNX65_RS01275 9f8063336e0f055bfe532b16c6c29d7d 293 Pfam PF01380 SIS domain 126 253 2.0E-23 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS01275 9f8063336e0f055bfe532b16c6c29d7d 293 SUPERFAMILY SSF46689 2 71 5.2E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS29940 431cc81861656a8b528318506397d956 114 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 9 90 3.2E-24 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CNX65_RS29940 431cc81861656a8b528318506397d956 114 Pfam PF12823 Domain of unknown function (DUF3817) 7 91 1.8E-22 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 Gene3D G3DSA:1.20.1560.10 1 317 8.8E-52 T 28-03-2018 CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 SUPERFAMILY SSF52540 330 560 1.18E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 SUPERFAMILY SSF90123 4 312 2.49E-57 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 Pfam PF00005 ABC transporter 347 492 4.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 ProSitePatterns PS00211 ABC transporters family signature. 464 478 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 SMART SM00382 354 538 3.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 Pfam PF00664 ABC transporter transmembrane region 16 282 3.0E-34 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS14050 780bf5ce000167e18067df7d6c7dbeab 581 Gene3D G3DSA:3.40.50.300 326 571 1.2E-62 T 28-03-2018 CNX65_RS09435 c3c42242e75c702001ea7d01b236a08b 1086 Pfam PF13569 Domain of unknown function (DUF4132) 832 1011 1.2E-49 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS26145 3f9569f684d1ff18489c3f20c66af9d4 368 SUPERFAMILY SSF56796 11 353 5.63E-100 T 28-03-2018 CNX65_RS26145 3f9569f684d1ff18489c3f20c66af9d4 368 Gene3D G3DSA:3.40.50.1970 5 171 1.2E-44 T 28-03-2018 CNX65_RS26145 3f9569f684d1ff18489c3f20c66af9d4 368 Pfam PF01761 3-dehydroquinate synthase 66 323 4.9E-93 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS26145 3f9569f684d1ff18489c3f20c66af9d4 368 Gene3D G3DSA:1.20.1090.10 172 360 2.3E-57 T 28-03-2018 CNX65_RS26145 3f9569f684d1ff18489c3f20c66af9d4 368 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 15 338 3.2E-106 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS26145 3f9569f684d1ff18489c3f20c66af9d4 368 PIRSF PIRSF001455 4 353 2.2E-98 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS26145 3f9569f684d1ff18489c3f20c66af9d4 368 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 5 355 37.342 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS07985 95e5f289556207c0ac0023327a182931 318 SMART SM00829 10 314 5.2E-21 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS07985 95e5f289556207c0ac0023327a182931 318 Gene3D G3DSA:3.40.50.720 139 241 1.5E-23 T 28-03-2018 CNX65_RS07985 95e5f289556207c0ac0023327a182931 318 Gene3D G3DSA:3.90.180.10 242 316 0.015 T 28-03-2018 CNX65_RS07985 95e5f289556207c0ac0023327a182931 318 SUPERFAMILY SSF50129 1 129 5.19E-28 T 28-03-2018 IPR011032 GroES-like CNX65_RS07985 95e5f289556207c0ac0023327a182931 318 Gene3D G3DSA:3.90.180.10 1 138 4.1E-37 T 28-03-2018 CNX65_RS07985 95e5f289556207c0ac0023327a182931 318 SUPERFAMILY SSF51735 102 281 7.89E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07985 95e5f289556207c0ac0023327a182931 318 Pfam PF00107 Zinc-binding dehydrogenase 141 259 8.4E-31 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 SUPERFAMILY SSF52172 3 122 2.99E-31 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 SMART SM00448 2 117 4.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 PIRSF PIRSF000876 1 386 3.4E-124 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 SUPERFAMILY SSF52738 194 383 6.15E-67 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 Gene3D G3DSA:3.40.50.2300 1 134 8.4E-33 T 28-03-2018 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 Pfam PF00072 Response regulator receiver domain 4 116 4.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 2 383 37.842 T 28-03-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 Gene3D G3DSA:3.40.50.180 191 388 8.7E-75 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CNX65_RS11805 001dcbd2d50192005c6506afcf5795e8 394 Pfam PF01339 CheB methylesterase 200 378 8.2E-61 T 28-03-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 CNX65_RS00790 33d152958284541cde71c49b08f2071e 271 SUPERFAMILY SSF56601 9 262 3.7E-52 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS00790 33d152958284541cde71c49b08f2071e 271 Pfam PF00144 Beta-lactamase 16 263 5.8E-33 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS00790 33d152958284541cde71c49b08f2071e 271 Gene3D G3DSA:3.40.710.10 3 271 5.7E-51 T 28-03-2018 CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 3.2E-16 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 SUPERFAMILY SSF48498 78 188 9.79E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 9.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 9.3E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 Gene3D G3DSA:1.10.357.10 58 193 2.1E-23 T 28-03-2018 CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 SUPERFAMILY SSF46689 7 68 5.99E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 Gene3D G3DSA:1.10.10.60 6 57 3.5E-19 T 28-03-2018 CNX65_RS14975 9bb3c6e87283e26919ae40e42c0fe682 197 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 99 191 4.8E-11 T 28-03-2018 CNX65_RS00455 b225aa25b332fb625b9d5bf5d2bff6c4 394 Gene3D G3DSA:2.30.30.230 2 99 1.9E-13 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CNX65_RS00455 b225aa25b332fb625b9d5bf5d2bff6c4 394 Gene3D G3DSA:3.90.850.10 100 373 3.8E-79 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS00455 b225aa25b332fb625b9d5bf5d2bff6c4 394 SUPERFAMILY SSF63433 2 86 7.19E-12 T 28-03-2018 IPR015377 Fumarylacetoacetase, N-terminal GO:0004334|GO:0009072 KEGG: 00350+3.7.1.2|KEGG: 00643+3.7.1.2|Reactome: R-HSA-71182 CNX65_RS00455 b225aa25b332fb625b9d5bf5d2bff6c4 394 SUPERFAMILY SSF56529 104 387 3.14E-83 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS00455 b225aa25b332fb625b9d5bf5d2bff6c4 394 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 107 376 9.4E-55 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 Gene3D G3DSA:2.60.120.10 10 114 2.1E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 Gene3D G3DSA:3.40.50.620 365 479 4.4E-13 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 SUPERFAMILY SSF47323 508 641 1.33E-7 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 136 147 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 SUPERFAMILY SSF52374 127 264 2.82E-53 T 28-03-2018 CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 SUPERFAMILY SSF52374 298 483 2.82E-53 T 28-03-2018 CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 Gene3D G3DSA:1.10.730.10 495 644 1.1E-8 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 SUPERFAMILY SSF51182 32 109 9.43E-16 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 Gene3D G3DSA:3.40.50.620 115 364 1.9E-27 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 Pfam PF09334 tRNA synthetases class I (M) 130 483 8.3E-57 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS21055 346ddbb8a3400de2565ceac3c58a1246 645 Pfam PF07883 Cupin domain 39 105 7.0E-13 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 Gene3D G3DSA:1.10.1660.10 2 56 5.8E-20 T 28-03-2018 CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 SUPERFAMILY SSF46955 4 101 1.32E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 Pfam PF13411 MerR HTH family regulatory protein 4 68 1.0E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 SMART SM00422 3 72 7.1E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 3.8E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 3.8E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 3.8E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS21900 69e3f93777757ce879bb736bb76c0d38 242 Gene3D G3DSA:1.10.1660.10 57 112 7.5E-9 T 28-03-2018 CNX65_RS10315 06718d78031f8bcd3f7ed2909eb76ebb 84 Pfam PF02467 Transcription factor WhiB 12 73 1.7E-22 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS10315 06718d78031f8bcd3f7ed2909eb76ebb 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 4 83 13.242 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS32680 06718d78031f8bcd3f7ed2909eb76ebb 84 Pfam PF02467 Transcription factor WhiB 12 73 1.7E-22 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS32680 06718d78031f8bcd3f7ed2909eb76ebb 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 4 83 13.242 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS19935 ba9405438c689ca623764698581fde17 341 Pfam PF01872 RibD C-terminal domain 148 309 3.6E-42 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 52 90 - T 28-03-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 101 3.3E-15 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CNX65_RS19935 ba9405438c689ca623764698581fde17 341 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 8 321 2.1E-88 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 Gene3D G3DSA:3.40.430.10 244 328 1.6E-18 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 SUPERFAMILY SSF53927 5 143 5.27E-40 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 PIRSF PIRSF006769 1 250 1.1E-90 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 PIRSF PIRSF006769 244 324 3.2E-12 T 28-03-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00040+1.1.1.19|KEGG: 00053+1.1.1.19|KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-5525 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 Gene3D G3DSA:3.40.140.10 3 123 5.6E-30 T 28-03-2018 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 SUPERFAMILY SSF53597 145 326 5.5E-46 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS19935 ba9405438c689ca623764698581fde17 341 Gene3D G3DSA:3.40.430.10 124 243 2.5E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 Pfam PF08220 DeoR-like helix-turn-helix domain 108 162 3.0E-16 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 SMART SM01134 173 333 1.9E-54 T 28-03-2018 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 Pfam PF00455 DeoR C terminal sensor domain 178 331 1.4E-41 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 SUPERFAMILY SSF100950 177 333 2.3E-28 T 28-03-2018 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 126 140 1.5E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 140 158 1.5E-7 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 SUPERFAMILY SSF46785 107 163 2.73E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 Gene3D G3DSA:3.40.50.1360 166 333 1.1E-35 T 28-03-2018 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 SMART SM00420 108 160 8.1E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 Gene3D G3DSA:1.10.10.10 101 160 4.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17460 8b5a308e37e953386cf47fe09a7e7d08 349 ProSitePatterns PS00894 DeoR-type HTH domain signature. 108 142 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CNX65_RS12500 611fcf84653f601fa3f06d49faacd5b9 118 SUPERFAMILY SSF52091 10 113 1.24E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS12500 611fcf84653f601fa3f06d49faacd5b9 118 Pfam PF01740 STAS domain 12 100 6.0E-6 T 28-03-2018 IPR002645 STAS domain CNX65_RS12500 611fcf84653f601fa3f06d49faacd5b9 118 Gene3D G3DSA:3.30.750.24 7 118 2.8E-15 T 28-03-2018 IPR002645 STAS domain CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 SUPERFAMILY SSF51905 215 360 1.51E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 SUPERFAMILY SSF51905 3 52 1.51E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 SUPERFAMILY SSF51905 89 187 1.51E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PIRSF PIRSF000350 2 437 1.2E-80 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 TIGRFAM TIGR03452 mycothione_red: mycothione reductase 2 454 7.3E-197 T 28-03-2018 IPR017817 Mycothione reductase MetaCyc: PWY-6421 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 341 450 1.5E-25 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 36 46 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 131 149 1.3E-25 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.3E-25 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 272 1.3E-25 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 285 307 1.3E-25 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 170 188 1.3E-25 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 300 307 1.8E-42 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 195 1.8E-42 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.8E-42 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 337 358 1.8E-42 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.8E-42 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 134 143 1.8E-42 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 1.8E-42 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 Gene3D G3DSA:3.50.50.60 1 161 2.2E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 SUPERFAMILY SSF55424 338 454 2.75E-29 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 Gene3D G3DSA:3.40.50.720 162 329 1.3E-27 T 28-03-2018 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 319 2.1E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28840 c4d0848f254fbc86726e01518cc089d4 459 Gene3D G3DSA:3.30.390.30 340 458 8.3E-32 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS18945 2f58862a1e5b0fcef377fe58d76ace85 331 SUPERFAMILY SSF89372 4 227 1.96E-44 T 28-03-2018 CNX65_RS18945 2f58862a1e5b0fcef377fe58d76ace85 331 Gene3D G3DSA:2.120.10.70 1 130 1.2E-35 T 28-03-2018 CNX65_RS18945 2f58862a1e5b0fcef377fe58d76ace85 331 Gene3D G3DSA:2.120.10.70 131 233 5.5E-24 T 28-03-2018 CNX65_RS18945 2f58862a1e5b0fcef377fe58d76ace85 331 Gene3D G3DSA:2.120.10.70 234 331 1.0E-21 T 28-03-2018 CNX65_RS18945 2f58862a1e5b0fcef377fe58d76ace85 331 SUPERFAMILY SSF89372 196 328 1.57E-22 T 28-03-2018 CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 45 68 2.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 24 37 2.2E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 3.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 Gene3D G3DSA:1.10.357.10 81 207 8.2E-19 T 28-03-2018 CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 Gene3D G3DSA:1.10.260.40 46 80 8.6E-11 T 28-03-2018 CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 Gene3D G3DSA:1.10.10.60 1 45 8.2E-14 T 28-03-2018 CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 SUPERFAMILY SSF48498 97 202 5.66E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS34485 d2ca5cb4d3065c6f0c07512d93ad1ddb 220 SUPERFAMILY SSF46689 11 84 1.45E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21700 b60e5cb0c753201562a290cc9efb0421 597 PIRSF PIRSF036654 39 596 6.0E-268 T 28-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 CNX65_RS21700 b60e5cb0c753201562a290cc9efb0421 597 Gene3D G3DSA:3.50.50.60 29 597 2.7E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21700 b60e5cb0c753201562a290cc9efb0421 597 SUPERFAMILY SSF51905 533 594 9.43E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21700 b60e5cb0c753201562a290cc9efb0421 597 SUPERFAMILY SSF51905 33 340 9.43E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21700 b60e5cb0c753201562a290cc9efb0421 597 Pfam PF00890 FAD binding domain 45 578 1.4E-100 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS28000 1543bb696b6cc27b17f42b80f65637b8 244 SUPERFAMILY SSF51366 3 240 2.02E-62 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS28000 1543bb696b6cc27b17f42b80f65637b8 244 Pfam PF00977 Histidine biosynthesis protein 5 234 1.5E-63 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CNX65_RS28000 1543bb696b6cc27b17f42b80f65637b8 244 TIGRFAM TIGR01919 hisA-trpF: bifunctional HisA/TrpF protein 2 243 2.5E-124 T 28-03-2018 IPR010188 Bifunctional HisA/TrpF GO:0000105|GO:0000162|GO:0003949|GO:0004640|GO:0005737 KEGG: 00340+5.3.1.16 CNX65_RS28000 1543bb696b6cc27b17f42b80f65637b8 244 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 4 241 32.532 T 28-03-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 CNX65_RS28000 1543bb696b6cc27b17f42b80f65637b8 244 Gene3D G3DSA:3.20.20.70 3 244 1.3E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 PRINTS PR00063 Ribosomal protein L27 signature 4 28 1.5E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 PRINTS PR00063 Ribosomal protein L27 signature 54 78 1.5E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 PRINTS PR00063 Ribosomal protein L27 signature 29 53 1.5E-36 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 TIGRFAM TIGR00062 L27: ribosomal protein bL27 1 81 3.0E-35 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 ProSitePatterns PS00831 Ribosomal protein L27 signature. 34 48 - T 28-03-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 Gene3D G3DSA:2.40.50.100 20 83 1.1E-28 T 28-03-2018 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 Pfam PF01016 Ribosomal L27 protein 2 80 5.3E-37 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 SUPERFAMILY SSF110324 2 81 4.88E-32 T 28-03-2018 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 28 70 2.0E-16 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05920 812e26c73969d31f41bd575f7e6a09da 87 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 1 83 27.937 T 28-03-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Gene3D G3DSA:1.10.1040.10 473 574 3.7E-16 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 359 471 4.5E-38 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 315 353 2.5E-8 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 SUPERFAMILY SSF48179 592 683 2.72E-20 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 SUPERFAMILY SSF52096 3 294 1.03E-57 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Gene3D G3DSA:3.40.50.720 254 472 5.1E-56 T 28-03-2018 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 SUPERFAMILY SSF51735 312 472 5.65E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Gene3D G3DSA:3.90.226.10 1 203 3.3E-46 T 28-03-2018 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 SUPERFAMILY SSF48179 473 582 8.5E-18 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 201 3.0E-29 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Gene3D G3DSA:1.10.1040.10 596 684 1.2E-16 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS27765 fd50b6972d85f1d1c635eb99735d7b1a 684 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 474 569 9.8E-18 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS16760 82c70d678d7117a7d782fd8a11cb8aef 266 SMART SM00530 12 85 8.4E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS16760 82c70d678d7117a7d782fd8a11cb8aef 266 SUPERFAMILY SSF47413 9 81 9.48E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS16760 82c70d678d7117a7d782fd8a11cb8aef 266 Gene3D G3DSA:1.10.260.40 1 96 9.7E-17 T 28-03-2018 CNX65_RS16760 82c70d678d7117a7d782fd8a11cb8aef 266 Pfam PF13560 Helix-turn-helix domain 8 88 1.4E-15 T 28-03-2018 CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 Gene3D G3DSA:2.60.40.10 185 288 6.1E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 Gene3D G3DSA:2.60.40.10 634 714 1.3E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 Gene3D G3DSA:2.60.40.10 722 809 1.3E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 SUPERFAMILY SSF49303 727 793 7.05E-6 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 SUPERFAMILY SSF49785 4 189 9.21E-50 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 Gene3D G3DSA:3.20.20.80 289 630 1.2E-83 T 28-03-2018 CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 Gene3D G3DSA:2.60.120.260 3 184 2.3E-42 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 SUPERFAMILY SSF51445 287 632 7.68E-101 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS30430 f3bcbcb0092cbe44a058a230b058d638 812 SUPERFAMILY SSF49303 192 290 1.81E-14 T 28-03-2018 IPR006102 Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich GO:0004553|GO:0005975 CNX65_RS33415 3a06fabab0d5f14bf3b2a4f15d51e984 136 Pfam PF13453 Transcription factor zinc-finger 3 41 2.5E-17 T 28-03-2018 IPR027392 Transcription factor zinc-finger CNX65_RS04175 fc99f662a84545297013b805f69a08d3 359 Pfam PF02254 TrkA-N domain 143 261 1.0E-23 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CNX65_RS04175 fc99f662a84545297013b805f69a08d3 359 SUPERFAMILY SSF51735 139 284 5.52E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS04175 fc99f662a84545297013b805f69a08d3 359 Pfam PF07885 Ion channel 44 123 2.2E-12 T 28-03-2018 IPR013099 Potassium channel domain CNX65_RS04175 fc99f662a84545297013b805f69a08d3 359 Gene3D G3DSA:1.10.287.70 30 132 6.0E-14 T 28-03-2018 CNX65_RS04175 fc99f662a84545297013b805f69a08d3 359 SUPERFAMILY SSF81324 34 159 2.09E-18 T 28-03-2018 CNX65_RS04175 fc99f662a84545297013b805f69a08d3 359 Gene3D G3DSA:3.40.50.720 133 261 3.4E-22 T 28-03-2018 CNX65_RS11365 e1a0a5ceff398eb18a3902496b536726 304 SMART SM00382 28 206 9.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS11365 e1a0a5ceff398eb18a3902496b536726 304 Gene3D G3DSA:3.40.50.300 1 285 4.6E-59 T 28-03-2018 CNX65_RS11365 e1a0a5ceff398eb18a3902496b536726 304 SUPERFAMILY SSF52540 2 220 3.06E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11365 e1a0a5ceff398eb18a3902496b536726 304 Pfam PF00005 ABC transporter 20 158 1.3E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS11365 e1a0a5ceff398eb18a3902496b536726 304 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS31865 9312e2708f20d9f12de2449bbc3a1bb7 1176 Pfam PF14021 Tuberculosis necrotizing toxin 1082 1168 9.2E-26 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CNX65_RS31865 9312e2708f20d9f12de2449bbc3a1bb7 1176 SUPERFAMILY SSF160424 14 147 1.18E-16 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 170 240 1.6E-26 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 169 241 7.4E-29 T 28-03-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 Gene3D G3DSA:2.30.330.10 161 250 2.8E-28 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 SUPERFAMILY SSF101801 168 244 7.59E-24 T 28-03-2018 IPR001543 Surface presentation of antigen (SpoA) CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 PRINTS PR00956 Flagellar motor switch protein FliN signature 187 203 1.3E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 PRINTS PR00956 Flagellar motor switch protein FliN signature 216 231 1.3E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 PRINTS PR00956 Flagellar motor switch protein FliN signature 170 186 1.3E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CNX65_RS11880 40759896f4819d5346ed2493f615fa5f 250 PRINTS PR00956 Flagellar motor switch protein FliN signature 203 216 1.3E-25 T 28-03-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 PIRSF PIRSF004862 4 558 1.6E-129 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 Pfam PF01514 Secretory protein of YscJ/FliF family 32 221 1.7E-66 T 28-03-2018 IPR006182 Secretory protein YscJ/FliF CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 Gene3D G3DSA:3.30.70.1530 53 116 5.7E-7 T 28-03-2018 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 PRINTS PR01009 Flagellar M-ring protein signature 349 373 2.9E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 PRINTS PR01009 Flagellar M-ring protein signature 154 168 2.9E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 PRINTS PR01009 Flagellar M-ring protein signature 122 140 2.9E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 PRINTS PR01009 Flagellar M-ring protein signature 268 286 2.9E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 PRINTS PR01009 Flagellar M-ring protein signature 197 215 2.9E-23 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 17 556 7.0E-83 T 28-03-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 CNX65_RS11950 5f0a0e22fa209a6c173a1373989e8451 559 Pfam PF08345 Flagellar M-ring protein C-terminal 255 413 7.9E-32 T 28-03-2018 IPR013556 Flagellar M-ring C-terminal CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 Gene3D G3DSA:3.40.50.1860 4 122 1.6E-25 T 28-03-2018 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 Gene3D G3DSA:3.40.50.1860 123 262 9.9E-42 T 28-03-2018 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 TIGRFAM TIGR00067 glut_race: glutamate racemase 8 251 2.9E-69 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 SUPERFAMILY SSF53681 111 253 1.96E-38 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 181 191 - T 28-03-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 72 80 - T 28-03-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 Pfam PF01177 Asp/Glu/Hydantoin racemase 8 216 1.6E-32 T 28-03-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 SUPERFAMILY SSF53681 7 109 3.6E-33 T 28-03-2018 IPR001920 Asp/Glu racemase GO:0008152|GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS05090 bae16ca5528d2a2b0b42d9f6db48cc15 264 Hamap MF_00258 Glutamate racemase [murI]. 6 255 36.515 T 28-03-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 Pfam PF00196 Bacterial regulatory proteins, luxR family 140 195 1.2E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 Gene3D G3DSA:3.40.50.2300 1 125 1.5E-35 T 28-03-2018 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 SMART SM00421 138 195 2.0E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 SUPERFAMILY SSF52172 2 129 1.08E-31 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 141 155 9.9E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 171 9.9E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 171 183 9.9E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 SMART SM00448 2 115 3.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 Gene3D G3DSA:1.10.10.10 126 201 3.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 Pfam PF00072 Response regulator receiver domain 4 116 1.7E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS09675 b27c21390de95ddd6ea1765aaea4a28c 201 SUPERFAMILY SSF46894 132 201 1.67E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1249 1311 1.2E-19 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Gene3D G3DSA:1.10.287.850 78 173 1.4E-10 T 28-03-2018 CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 SUPERFAMILY SSF140453 87 174 1.2E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Pfam PF05593 RHS Repeat 885 922 2.7E-10 T 28-03-2018 IPR031325 RHS repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Pfam PF05593 RHS Repeat 826 859 8.4E-6 T 28-03-2018 IPR031325 RHS repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Pfam PF05593 RHS Repeat 580 613 1.3E-4 T 28-03-2018 IPR031325 RHS repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Pfam PF05593 RHS Repeat 662 699 3.6E-9 T 28-03-2018 IPR031325 RHS repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Pfam PF05593 RHS Repeat 1131 1166 2.2E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Pfam PF05593 RHS Repeat 907 935 1.4E-5 T 28-03-2018 IPR031325 RHS repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 Pfam PF05593 RHS Repeat 865 899 3.5E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 926 960 2.8E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 843 882 7.6E-7 T 28-03-2018 IPR006530 YD repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 558 593 7.3E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1131 1159 5.6E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 662 699 2.7E-8 T 28-03-2018 IPR006530 YD repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 878 905 1.4E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS15810 1c5a03bf511d8bafba948dcfa6a2e1a4 1551 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 906 936 8.8E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 SUPERFAMILY SSF50494 5 245 2.82E-68 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 Gene3D G3DSA:2.40.10.10 58 118 3.3E-20 T 28-03-2018 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 195 206 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 SMART SM00020 25 240 1.4E-73 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 53 68 8.6E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 194 206 8.6E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 109 123 8.6E-13 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 Gene3D G3DSA:2.40.10.10 119 246 5.3E-40 T 28-03-2018 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 Pfam PF00089 Trypsin 26 240 1.9E-56 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 63 68 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS28795 30b7713f59b55c086f8d7fdc01629c55 246 Gene3D G3DSA:2.40.10.10 26 57 2.7E-14 T 28-03-2018 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 Gene3D G3DSA:3.30.950.10 127 252 3.4E-28 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 SUPERFAMILY SSF69618 238 489 6.15E-71 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 SUPERFAMILY SSF53790 5 241 7.72E-46 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 10 203 1.6E-35 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 14 28 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 Gene3D G3DSA:3.40.1010.10 9 126 4.9E-28 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 Gene3D G3DSA:3.40.50.10090 399 493 9.3E-24 T 28-03-2018 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 Gene3D G3DSA:3.40.50.10090 270 398 1.5E-30 T 28-03-2018 CNX65_RS33155 85b10df7259031278bd4beba0a0be30b 510 Pfam PF02602 Uroporphyrinogen-III synthase HemD 252 482 1.9E-65 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS29310 6aa82190f49025eaa00c0574032d405f 188 Gene3D G3DSA:3.40.50.150 1 187 3.2E-36 T 28-03-2018 CNX65_RS29310 6aa82190f49025eaa00c0574032d405f 188 PIRSF PIRSF004553 1 185 8.2E-53 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CNX65_RS29310 6aa82190f49025eaa00c0574032d405f 188 SUPERFAMILY SSF53335 2 180 1.67E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS29310 6aa82190f49025eaa00c0574032d405f 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 3 182 1.7E-46 T 28-03-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 CNX65_RS29310 6aa82190f49025eaa00c0574032d405f 188 Pfam PF03602 Conserved hypothetical protein 95 2 179 8.5E-47 T 28-03-2018 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 SUPERFAMILY SSF52440 2 114 8.63E-46 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Pfam PF00289 Biotin carboxylase, N-terminal domain 3 111 6.2E-43 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Pfam PF02785 Biotin carboxylase C-terminal domain 336 446 4.9E-34 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 SUPERFAMILY SSF51246 330 450 7.85E-36 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 SMART SM00878 336 446 8.4E-54 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Gene3D G3DSA:3.40.50.20 2 124 2.3E-48 T 28-03-2018 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Gene3D G3DSA:3.30.1490.20 125 210 1.6E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 SUPERFAMILY SSF51230 517 586 1.2E-20 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Gene3D G3DSA:3.30.470.20 211 449 8.2E-90 T 28-03-2018 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Gene3D G3DSA:2.40.50.100 518 588 3.0E-19 T 28-03-2018 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 SUPERFAMILY SSF56059 84 328 4.95E-59 T 28-03-2018 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Pfam PF00364 Biotin-requiring enzyme 521 586 1.3E-17 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 543 560 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS31410 c47c4f6a8ac1d9ec4b4c6c766c95ffd0 588 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 5.1E-75 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS11225 4798b08c4d51ccbd20e4907a7b552d0a 226 Pfam PF12389 Camelysin metallo-endopeptidase 25 220 3.1E-10 T 28-03-2018 IPR022121 Peptidase M73, camelysin CNX65_RS21050 eba37cb4fff81c24cc37b9c058070748 357 SUPERFAMILY SSF51905 310 351 4.92E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21050 eba37cb4fff81c24cc37b9c058070748 357 SUPERFAMILY SSF51905 7 216 4.92E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21050 eba37cb4fff81c24cc37b9c058070748 357 Pfam PF01266 FAD dependent oxidoreductase 8 347 1.8E-41 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS21050 eba37cb4fff81c24cc37b9c058070748 357 Gene3D G3DSA:3.50.50.60 1 356 8.2E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS17315 7521456b2a6ab2b95e1fbd1303e69d2b 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 14 94 6.9E-13 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS17315 7521456b2a6ab2b95e1fbd1303e69d2b 151 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 16 140 3.0E-36 T 28-03-2018 IPR019920 F420-binding domain, putative CNX65_RS17315 7521456b2a6ab2b95e1fbd1303e69d2b 151 Gene3D G3DSA:2.30.110.10 3 135 6.1E-24 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS17315 7521456b2a6ab2b95e1fbd1303e69d2b 151 SUPERFAMILY SSF50475 14 139 1.53E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 Pfam PF07650 KH domain 208 287 1.6E-15 T 28-03-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 11 168 6.2E-21 T 28-03-2018 IPR005225 Small GTP-binding protein domain GO:0005525 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 Pfam PF01926 50S ribosome-binding GTPase 9 124 1.8E-20 T 28-03-2018 IPR006073 GTP binding domain GO:0005525 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 Gene3D G3DSA:3.40.50.300 5 23 0.15 T 28-03-2018 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 SUPERFAMILY SSF52540 10 213 3.65E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 SUPERFAMILY SSF54814 182 298 7.85E-35 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 Gene3D G3DSA:3.30.300.20 185 298 1.9E-41 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 Hamap MF_00367 GTPase Era [era]. 4 298 35.084 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 TIGRFAM TIGR00436 era: GTP-binding protein Era 7 281 7.3E-71 T 28-03-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS06250 ea5ab99deca2835c8fabcfb2f3d0d630 298 Gene3D G3DSA:3.40.50.300 24 176 3.2E-33 T 28-03-2018 CNX65_RS28540 9e4c33f6d08d4cbf84a03250e3595255 167 Gene3D G3DSA:1.10.357.10 54 165 8.8E-4 T 28-03-2018 CNX65_RS08085 1d307f160c5fd86605365ef59af724e4 339 Gene3D G3DSA:3.90.550.10 2 243 1.1E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08085 1d307f160c5fd86605365ef59af724e4 339 Pfam PF00535 Glycosyl transferase family 2 11 124 7.0E-32 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS08085 1d307f160c5fd86605365ef59af724e4 339 SUPERFAMILY SSF53448 5 217 7.07E-49 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 Gene3D G3DSA:4.10.320.10 164 211 6.4E-15 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 Gene3D G3DSA:3.30.559.10 212 447 6.0E-72 T 28-03-2018 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 Pfam PF02817 e3 binding domain 166 199 3.2E-13 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 SUPERFAMILY SSF47005 164 201 2.09E-9 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 Gene3D G3DSA:3.90.1170.30 1 45 1.5E-12 T 28-03-2018 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 SUPERFAMILY SSF52777 216 444 1.96E-66 T 28-03-2018 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 227 444 8.3E-65 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 SUPERFAMILY SSF51230 3 92 2.88E-22 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 Gene3D G3DSA:2.40.50.100 46 163 2.1E-4 T 28-03-2018 CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 Pfam PF00364 Biotin-requiring enzyme 3 73 4.1E-15 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS24675 efd171ebede5a84fe53061c10952684d 447 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 26 55 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CNX65_RS15880 e0e9faadcecab3f096282138acaa0dc6 289 Pfam PF00196 Bacterial regulatory proteins, luxR family 214 265 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15880 e0e9faadcecab3f096282138acaa0dc6 289 SMART SM00421 212 269 3.5E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15880 e0e9faadcecab3f096282138acaa0dc6 289 SUPERFAMILY SSF46894 211 271 1.05E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS15880 e0e9faadcecab3f096282138acaa0dc6 289 Gene3D G3DSA:1.10.10.10 6 279 1.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15880 e0e9faadcecab3f096282138acaa0dc6 289 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 215 229 2.0E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15880 e0e9faadcecab3f096282138acaa0dc6 289 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 229 245 2.0E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15880 e0e9faadcecab3f096282138acaa0dc6 289 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 245 257 2.0E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS01655 dafe510101d35a258bc8491b0a9583ef 305 SUPERFAMILY SSF53335 7 287 1.08E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS01655 dafe510101d35a258bc8491b0a9583ef 305 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 151 230 1.7E-7 T 28-03-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 CNX65_RS01655 dafe510101d35a258bc8491b0a9583ef 305 Gene3D G3DSA:3.40.50.150 17 263 6.1E-4 T 28-03-2018 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 SUPERFAMILY SSF47644 636 719 6.41E-24 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Pfam PF00809 Pterin binding enzyme 343 579 2.1E-45 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Pfam PF02574 Homocysteine S-methyltransferase 18 308 2.5E-62 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Gene3D G3DSA:3.40.50.280 714 884 2.1E-46 T 28-03-2018 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Gene3D G3DSA:3.20.20.330 3 320 5.6E-89 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 SUPERFAMILY SSF56507 896 1178 8.11E-86 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 SUPERFAMILY SSF82282 7 382 7.98E-107 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Gene3D G3DSA:3.10.196.10 948 1178 9.7E-60 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 968 1177 2.0E-32 T 28-03-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Gene3D G3DSA:3.20.20.20 328 625 5.1E-50 T 28-03-2018 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Pfam PF02310 B12 binding domain 726 837 1.7E-19 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Gene3D G3DSA:1.10.1240.10 626 713 1.2E-31 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 SUPERFAMILY SSF52242 720 856 8.63E-39 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 SMART SM01018 638 720 3.8E-40 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 PIRSF PIRSF000381 3 1178 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 SUPERFAMILY SSF51717 340 611 1.3E-77 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 TIGRFAM TIGR02082 metH: methionine synthase 14 1177 0.0 T 28-03-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS11260 2fa040f5cc3edc81f314afcce3ceabd6 1178 Pfam PF02607 B12 binding domain 641 713 2.8E-25 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS19295 259cefa99e993d4713712868761b7814 513 SUPERFAMILY SSF55469 326 510 6.85E-11 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS19295 259cefa99e993d4713712868761b7814 513 Pfam PF00881 Nitroreductase family 344 509 3.5E-5 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS19295 259cefa99e993d4713712868761b7814 513 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 13 264 5.5E-30 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CNX65_RS19295 259cefa99e993d4713712868761b7814 513 Gene3D G3DSA:3.40.109.10 275 512 1.4E-21 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS19295 259cefa99e993d4713712868761b7814 513 TIGRFAM TIGR03891 thiopep_ocin: thiopeptide-type bacteriocin biosynthesis domain 100 262 6.9E-14 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CNX65_RS16200 2de5931313131fd4a82d6747addd9d6a 306 Gene3D G3DSA:3.40.50.720 5 198 4.3E-40 T 28-03-2018 CNX65_RS16200 2de5931313131fd4a82d6747addd9d6a 306 SUPERFAMILY SSF51735 25 199 3.95E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16200 2de5931313131fd4a82d6747addd9d6a 306 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 200 296 7.5E-27 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS16200 2de5931313131fd4a82d6747addd9d6a 306 SUPERFAMILY SSF48179 199 301 1.62E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS16200 2de5931313131fd4a82d6747addd9d6a 306 Gene3D G3DSA:1.10.1040.10 199 300 3.2E-26 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS16200 2de5931313131fd4a82d6747addd9d6a 306 PIRSF PIRSF000105 17 305 4.9E-96 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CNX65_RS16200 2de5931313131fd4a82d6747addd9d6a 306 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 27 197 2.0E-40 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS01840 0821bb8f2364340324f56317e2b05026 476 PIRSF PIRSF016636 1 476 8.1E-148 T 28-03-2018 IPR024194 Alginate O-acetyltransferase AlgI/D-alanyl transfer protein DltB CNX65_RS01840 0821bb8f2364340324f56317e2b05026 476 Pfam PF03062 MBOAT, membrane-bound O-acyltransferase family 152 346 1.0E-28 T 28-03-2018 IPR004299 Membrane bound O-acyl transferase, MBOAT CNX65_RS01840 0821bb8f2364340324f56317e2b05026 476 PIRSF PIRSF500217 1 476 3.8E-150 T 28-03-2018 IPR028362 Alginate O-acetyltransferase AlgI GO:0042121 CNX65_RS15505 c3b43ad92823c6e3adaf22d2965859c8 388 SUPERFAMILY SSF55874 291 382 1.66E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS15505 c3b43ad92823c6e3adaf22d2965859c8 388 Pfam PF07730 Histidine kinase 192 254 3.2E-14 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS15505 c3b43ad92823c6e3adaf22d2965859c8 388 Gene3D G3DSA:3.30.565.10 258 388 5.7E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 Gene3D G3DSA:3.40.50.2300 82 247 8.2E-40 T 28-03-2018 CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 ProSitePatterns PS00356 LacI-type HTH domain signature. 11 29 - T 28-03-2018 CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 Gene3D G3DSA:3.40.50.2300 43 81 6.4E-11 T 28-03-2018 CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 Pfam PF13377 Periplasmic binding protein-like domain 84 244 2.5E-34 T 28-03-2018 CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 50 1.2E-13 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 SUPERFAMILY SSF53822 32 244 2.14E-46 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 SMART SM00354 8 65 3.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS15430 5c7a5c898784deca293b38afb0e3a5b6 247 Gene3D G3DSA:1.10.260.40 9 42 3.6E-11 T 28-03-2018 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 Gene3D G3DSA:1.10.10.10 135 214 1.2E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 SMART SM00448 2 116 1.2E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 SUPERFAMILY SSF46894 137 214 1.63E-21 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 Pfam PF00072 Response regulator receiver domain 4 117 5.4E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 Gene3D G3DSA:3.40.50.2300 1 134 9.2E-37 T 28-03-2018 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 SMART SM00421 152 209 2.9E-21 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 SUPERFAMILY SSF52172 3 134 3.27E-32 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 169 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 169 185 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 185 197 1.2E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 154 209 7.1E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21345 9fb5f187dd165a600cf582ef3ac07424 217 ProSitePatterns PS00622 LuxR-type HTH domain signature. 169 196 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27830 24633d01ca72e583ccd612949196c8ef 739 Gene3D G3DSA:3.40.1050.10 529 739 2.0E-68 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS27830 24633d01ca72e583ccd612949196c8ef 739 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 576 583 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS27830 24633d01ca72e583ccd612949196c8ef 739 Pfam PF00916 Sulfate permease family 27 374 5.1E-58 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CNX65_RS27830 24633d01ca72e583ccd612949196c8ef 739 SUPERFAMILY SSF53056 526 732 2.75E-55 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS27830 24633d01ca72e583ccd612949196c8ef 739 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 617 637 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS27830 24633d01ca72e583ccd612949196c8ef 739 Pfam PF00484 Carbonic anhydrase 572 724 3.0E-47 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS27830 24633d01ca72e583ccd612949196c8ef 739 SMART SM00947 564 728 4.9E-57 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS04915 5ac5356e7e0708f5c171feacff5e9b5d 192 Gene3D G3DSA:3.90.79.10 4 187 1.7E-29 T 28-03-2018 CNX65_RS04915 5ac5356e7e0708f5c171feacff5e9b5d 192 SUPERFAMILY SSF55811 9 181 7.31E-33 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS04915 5ac5356e7e0708f5c171feacff5e9b5d 192 Pfam PF00293 NUDIX domain 47 157 2.1E-14 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS08735 5473fd77f026953f787ebeec737fbaf4 719 SUPERFAMILY SSF53756 409 699 6.28E-21 T 28-03-2018 CNX65_RS08735 5473fd77f026953f787ebeec737fbaf4 719 SUPERFAMILY SSF53448 3 247 1.56E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08735 5473fd77f026953f787ebeec737fbaf4 719 Pfam PF13692 Glycosyl transferases group 1 545 676 1.1E-10 T 28-03-2018 CNX65_RS08735 5473fd77f026953f787ebeec737fbaf4 719 Gene3D G3DSA:3.90.550.10 1 289 8.2E-32 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08735 5473fd77f026953f787ebeec737fbaf4 719 Gene3D G3DSA:3.40.50.2000 500 690 7.9E-17 T 28-03-2018 CNX65_RS08735 5473fd77f026953f787ebeec737fbaf4 719 Pfam PF00535 Glycosyl transferase family 2 5 120 1.2E-16 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS30750 69a6f7c6c2ae0900c622e5244e87711c 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 5 126 35.173 T 28-03-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CNX65_RS30750 69a6f7c6c2ae0900c622e5244e87711c 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 51 80 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CNX65_RS30750 69a6f7c6c2ae0900c622e5244e87711c 127 SUPERFAMILY SSF51230 4 125 5.5E-38 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS30750 69a6f7c6c2ae0900c622e5244e87711c 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 4 125 2.5E-41 T 28-03-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 CNX65_RS30750 69a6f7c6c2ae0900c622e5244e87711c 127 Pfam PF01597 Glycine cleavage H-protein 8 124 2.8E-37 T 28-03-2018 IPR033753 Glycine cleavage system H-protein/Simiate CNX65_RS30750 69a6f7c6c2ae0900c622e5244e87711c 127 Gene3D G3DSA:2.40.50.100 6 127 4.3E-40 T 28-03-2018 CNX65_RS24550 7aaa4eb8e55aa1df4c9693c4b90133cd 145 SUPERFAMILY SSF50475 33 136 5.42E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS24550 7aaa4eb8e55aa1df4c9693c4b90133cd 145 Gene3D G3DSA:2.30.110.10 7 144 5.6E-45 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS24550 7aaa4eb8e55aa1df4c9693c4b90133cd 145 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 31 142 1.7E-36 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CNX65_RS24550 7aaa4eb8e55aa1df4c9693c4b90133cd 145 Pfam PF04075 F420H(2)-dependent quinone reductase 14 142 5.2E-54 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CNX65_RS05845 a2a25a7d06c12b97fdee530f5f124576 306 Gene3D G3DSA:3.40.50.300 2 274 3.4E-70 T 28-03-2018 CNX65_RS05845 a2a25a7d06c12b97fdee530f5f124576 306 SMART SM00382 30 213 3.9E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05845 a2a25a7d06c12b97fdee530f5f124576 306 Pfam PF00005 ABC transporter 22 164 2.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS05845 a2a25a7d06c12b97fdee530f5f124576 306 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS05845 a2a25a7d06c12b97fdee530f5f124576 306 SUPERFAMILY SSF52540 4 228 2.02E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 Hamap MF_00372 Imidazolonepropionase [hutI]. 2 380 40.771 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 Gene3D G3DSA:3.20.20.140 74 339 6.7E-51 T 28-03-2018 CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 TIGRFAM TIGR01224 hutI: imidazolonepropionase 23 377 9.4E-101 T 28-03-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 SUPERFAMILY SSF51338 320 377 4.46E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 SUPERFAMILY SSF51338 13 71 1.81E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 SUPERFAMILY SSF51556 58 338 4.54E-68 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 Pfam PF01979 Amidohydrolase family 56 354 3.9E-15 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS30830 2492e7e7fec5aeb6d9746c6e4a7bd748 381 Gene3D G3DSA:2.30.40.10 2 73 5.7E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 54 474 38.759 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 Gene3D G3DSA:3.20.20.10 73 318 2.0E-63 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 44 474 1.1E-141 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 SUPERFAMILY SSF51419 65 334 6.54E-74 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 269 286 - T 28-03-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 230 243 3.2E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 95 113 3.2E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 431 444 3.2E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 115 127 3.2E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 323 342 3.2E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 339 431 6.0E-14 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 441 463 7.6E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 356 374 7.6E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 202 211 7.6E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 PRINTS PR01181 Diaminopimelate decarboxylase signature 113 130 7.6E-27 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 74 333 1.9E-61 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 Gene3D G3DSA:2.40.37.10 319 474 9.6E-37 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 95 113 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CNX65_RS30305 9da20e24b0223755ab177396193189c9 474 SUPERFAMILY SSF50621 308 474 5.86E-46 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 4.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 4.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 4.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 4.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 4.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 4.1E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 244 9.3E-64 T 28-03-2018 CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 5.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 5.3E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 SUPERFAMILY SSF51735 6 246 2.62E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 Gene3D G3DSA:3.40.50.720 48 250 2.0E-55 T 28-03-2018 CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 Gene3D G3DSA:3.40.50.720 1 47 5.8E-12 T 28-03-2018 CNX65_RS25520 eaf18067405aaa0761ea08443c62c557 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:2.80.10.50 1091 1128 1.2E-6 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SMART SM00458 910 1007 0.44 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SMART SM00458 1008 1127 6.5E-20 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:2.80.10.50 905 994 4.7E-10 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SUPERFAMILY SSF50370 1016 1126 1.66E-31 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Pfam PF03422 Carbohydrate binding module (family 6) 155 261 7.6E-8 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SUPERFAMILY SSF50370 916 997 1.58E-12 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Pfam PF00652 Ricin-type beta-trefoil lectin domain 1016 1124 1.4E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:4.10.1090.10 995 1055 1.5E-11 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Pfam PF17137 Domain of unknown function (DUF5110) 789 856 6.7E-15 T 28-03-2018 IPR033403 Domain of unknown function DUF5110 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:2.60.40.1180 768 888 2.3E-20 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Pfam PF01055 Glycosyl hydrolases family 31 345 771 3.7E-77 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SUPERFAMILY SSF51011 683 766 1.15E-18 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:2.80.10.50 1056 1090 3.6E-13 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:3.20.20.80 336 702 1.0E-64 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:2.60.120.260 129 271 4.5E-25 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SUPERFAMILY SSF49785 129 262 3.83E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SUPERFAMILY SSF51445 353 681 5.15E-33 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 Gene3D G3DSA:2.60.40.1180 703 767 2.0E-19 T 28-03-2018 CNX65_RS00550 93ccb7124834078c972569ed6f615962 1128 SMART SM00606 125 262 0.0062 T 28-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Pfam PF00550 Phosphopantetheine attachment site 547 609 2.5E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 SUPERFAMILY SSF56801 28 558 3.01E-142 T 28-03-2018 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Pfam PF00501 AMP-binding enzyme 39 434 2.7E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 SMART SM00823 Phosphopantetheine attachment site 545 614 3.1E-8 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Gene3D G3DSA:2.30.38.10 348 424 6.5E-24 T 28-03-2018 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Gene3D G3DSA:3.40.50.980 162 347 1.8E-47 T 28-03-2018 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 SUPERFAMILY SSF47336 539 610 2.88E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 58 458 2.7E-117 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Gene3D G3DSA:3.30.300.30 429 552 3.9E-37 T 28-03-2018 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Gene3D G3DSA:3.40.50.980 29 161 2.2E-30 T 28-03-2018 CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Pfam PF13193 AMP-binding enzyme C-terminal domain 442 517 2.0E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS22415 17282641bd6e23961238ce978a2ec760 636 Gene3D G3DSA:1.10.1200.10 553 622 4.1E-24 T 28-03-2018 CNX65_RS28140 3aaeae4377bd0ee841f15b634dbb734f 423 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 240 277 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS28140 3aaeae4377bd0ee841f15b634dbb734f 423 Pfam PF00202 Aminotransferase class-III 25 409 1.8E-110 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS28140 3aaeae4377bd0ee841f15b634dbb734f 423 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 14 413 1.1E-159 T 28-03-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 CNX65_RS28140 3aaeae4377bd0ee841f15b634dbb734f 423 SUPERFAMILY SSF53383 5 414 3.07E-113 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS28140 3aaeae4377bd0ee841f15b634dbb734f 423 Gene3D G3DSA:3.40.640.10 53 314 8.1E-69 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS28140 3aaeae4377bd0ee841f15b634dbb734f 423 Gene3D G3DSA:3.90.1150.10 315 423 1.0E-20 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS02225 4e24bae5de0b220d5788fd2e32194a6d 202 SUPERFAMILY SSF51219 4 199 3.4E-31 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CNX65_RS02225 4e24bae5de0b220d5788fd2e32194a6d 202 Pfam PF01987 Mitochondrial biogenesis AIM24 10 196 1.9E-24 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CNX65_RS02225 4e24bae5de0b220d5788fd2e32194a6d 202 Gene3D G3DSA:3.60.160.10 1 202 2.4E-26 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 Gene3D G3DSA:3.40.190.10 93 175 1.6E-13 T 28-03-2018 CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 SUPERFAMILY SSF46785 5 111 1.31E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 Gene3D G3DSA:1.10.10.10 1 89 1.1E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 SUPERFAMILY SSF53850 90 265 1.1E-22 T 28-03-2018 CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 Gene3D G3DSA:3.40.190.10 176 260 1.0E-11 T 28-03-2018 CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 Pfam PF03466 LysR substrate binding domain 89 264 1.5E-24 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 66 3.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 33 43 5.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 22 33 5.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS21585 3bd70c6cddd634ae5bd86d21be8315e7 303 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 43 54 5.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS13195 b3f07dd7e36d670247abaf1296d9d40d 133 Gene3D G3DSA:1.10.10.10 11 87 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13195 b3f07dd7e36d670247abaf1296d9d40d 133 SMART SM00345 20 79 2.1E-6 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS13195 b3f07dd7e36d670247abaf1296d9d40d 133 Pfam PF00392 Bacterial regulatory proteins, gntR family 18 79 8.8E-9 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS13195 b3f07dd7e36d670247abaf1296d9d40d 133 SUPERFAMILY SSF46785 10 83 6.13E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 Pfam PF00069 Protein kinase domain 9 260 4.0E-41 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 15 38 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 Gene3D G3DSA:3.30.200.20 3 105 8.6E-22 T 28-03-2018 CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 Gene3D G3DSA:1.10.510.10 106 368 1.2E-40 T 28-03-2018 CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 SMART SM00220 9 267 1.3E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 SUPERFAMILY SSF56112 5 268 1.13E-66 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 SUPERFAMILY SSF56112 310 346 1.13E-66 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS26925 1a1f0b660bfbeeaf46f15983573bf6a3 621 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 127 139 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS01440 e82595f1105c32ec51667ca9d1cc8bd4 55 Pfam PF14029 Protein of unknown function (DUF4244) 5 51 4.2E-14 T 28-03-2018 IPR025338 Protein of unknown function DUF4244 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 141 354 3.2E-63 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 Gene3D G3DSA:1.10.1140.10 360 470 7.2E-38 T 28-03-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 10 472 2.5E-242 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 SUPERFAMILY SSF52540 88 359 8.01E-85 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 13 84 6.4E-21 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 Gene3D G3DSA:2.40.10.170 1 86 4.8E-28 T 28-03-2018 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 SMART SM00382 153 416 5.5E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 Hamap MF_01347 ATP synthase subunit beta [atpB]. 8 472 54.4 T 28-03-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 SUPERFAMILY SSF50615 10 85 2.04E-22 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 SUPERFAMILY SSF47917 357 472 9.68E-50 T 28-03-2018 CNX65_RS30195 12e19e943b0e2b81b6e34c5bc4f0b0c0 475 Gene3D G3DSA:3.40.50.300 87 359 3.1E-84 T 28-03-2018 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 SUPERFAMILY SSF82114 174 307 4.14E-42 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 Pfam PF01687 Riboflavin kinase 184 306 6.9E-36 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 SUPERFAMILY SSF52374 16 175 1.69E-35 T 28-03-2018 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 Gene3D G3DSA:3.40.50.620 1 179 1.1E-48 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 PIRSF PIRSF004491 3 308 6.1E-100 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 18 304 5.4E-75 T 28-03-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 18 84 6.8E-9 T 28-03-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 SMART SM00904 183 308 5.3E-57 T 28-03-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 Reactome: R-HSA-196843 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 Gene3D G3DSA:2.40.30.30 180 309 1.3E-41 T 28-03-2018 IPR023465 Riboflavin kinase domain GO:0008531|GO:0009231 Reactome: R-HSA-196843 CNX65_RS28580 6ba2564bf7c158c1863705fdacc6906e 310 Pfam PF06574 FAD synthetase 16 166 3.3E-53 T 28-03-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 CNX65_RS13990 ea85a27ce61231fb90d9f1733b87b57f 822 Pfam PF02687 FtsX-like permease family 725 811 6.4E-10 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS33355 e74699bdd46cdb68ed2bae47c19871ca 177 Gene3D G3DSA:1.10.357.10 7 177 8.6E-28 T 28-03-2018 CNX65_RS33355 e74699bdd46cdb68ed2bae47c19871ca 177 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 94 176 1.3E-19 T 28-03-2018 CNX65_RS33355 e74699bdd46cdb68ed2bae47c19871ca 177 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 1.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS33355 e74699bdd46cdb68ed2bae47c19871ca 177 SUPERFAMILY SSF46689 3 70 2.0E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS33355 e74699bdd46cdb68ed2bae47c19871ca 177 SUPERFAMILY SSF48498 94 176 1.09E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS28410 deae9884188c5d4f5f19df555ae76fde 138 SUPERFAMILY SSF47413 3 70 6.76E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS28410 deae9884188c5d4f5f19df555ae76fde 138 Pfam PF13560 Helix-turn-helix domain 8 70 3.8E-12 T 28-03-2018 CNX65_RS28410 deae9884188c5d4f5f19df555ae76fde 138 Gene3D G3DSA:1.10.260.40 3 79 2.4E-15 T 28-03-2018 CNX65_RS28410 deae9884188c5d4f5f19df555ae76fde 138 SMART SM00530 12 67 7.4E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS15905 e589364bfb10194a1b71aff314f8daf2 243 SMART SM01007 12 189 4.2E-31 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15905 e589364bfb10194a1b71aff314f8daf2 243 Gene3D G3DSA:3.40.225.10 6 234 6.0E-46 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15905 e589364bfb10194a1b71aff314f8daf2 243 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 18 189 3.4E-32 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS15905 e589364bfb10194a1b71aff314f8daf2 243 SUPERFAMILY SSF53639 11 203 7.06E-43 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS06880 c288553e282c8f83543cc89a2a043c21 495 Pfam PF13581 Histidine kinase-like ATPase domain 377 483 3.9E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS06880 c288553e282c8f83543cc89a2a043c21 495 SUPERFAMILY SSF55874 392 484 3.41E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS06880 c288553e282c8f83543cc89a2a043c21 495 Pfam PF14417 MEDS: MEthanogen/methylotroph, DcmR Sensory domain 192 333 3.6E-18 T 28-03-2018 IPR025847 MEDS domain CNX65_RS06880 c288553e282c8f83543cc89a2a043c21 495 Gene3D G3DSA:3.30.565.10 367 495 3.6E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 Pfam PF00384 Molybdopterin oxidoreductase 121 500 3.0E-31 T 28-03-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 SUPERFAMILY SSF50692 640 762 1.08E-16 T 28-03-2018 IPR009010 Aspartate decarboxylase-like domain CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 Gene3D G3DSA:2.40.40.20 636 763 7.2E-23 T 28-03-2018 CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 PIRSF PIRSF000144 3 763 0.0 T 28-03-2018 CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 Pfam PF01568 Molydopterin dinucleotide binding domain 644 755 6.4E-9 T 28-03-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0030151|GO:0055114 CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 SUPERFAMILY SSF53706 59 634 5.37E-142 T 28-03-2018 CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 Gene3D G3DSA:3.40.50.740 334 620 3.1E-44 T 28-03-2018 CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 TIGRFAM TIGR01701 Fdhalpha-like: oxidoreductase alpha (molybdopterin) subunit 24 760 5.4E-292 T 28-03-2018 IPR010046 Oxidoreductase alpha (molybdopterin) subunit GO:0008863|GO:0030151|GO:0051539 CNX65_RS05790 4b5fa46e4f76f27ef764208ec9aa8571 763 Gene3D G3DSA:3.40.50.740 122 333 5.2E-39 T 28-03-2018 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 SUPERFAMILY SSF47917 383 511 2.88E-45 T 28-03-2018 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 29 95 6.4E-10 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 Gene3D G3DSA:3.40.50.300 86 375 1.5E-105 T 28-03-2018 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 382 507 9.5E-46 T 28-03-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 SUPERFAMILY SSF52540 99 381 1.47E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 6 512 2.7E-241 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 SUPERFAMILY SSF50615 14 97 3.14E-23 T 28-03-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0015992|GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 4 512 48.421 T 28-03-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 152 375 1.9E-66 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 366 375 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 Gene3D G3DSA:2.40.30.20 6 85 1.8E-28 T 28-03-2018 IPR023366 ATP synthase subunit alpha-like domain KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30205 aa8b1ba319d1cf6a1fb18b8595e41084 548 Gene3D G3DSA:1.20.150.20 384 511 1.6E-49 T 28-03-2018 CNX65_RS12745 f08f8c9231ca4084dccacdb151bec05e 1261 Pfam PF05762 VWA domain containing CoxE-like protein 1035 1255 1.4E-57 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CNX65_RS12745 f08f8c9231ca4084dccacdb151bec05e 1261 SUPERFAMILY SSF53300 1096 1246 2.97E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS12745 f08f8c9231ca4084dccacdb151bec05e 1261 Gene3D G3DSA:3.40.50.410 1065 1245 2.2E-13 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 Pfam PF02132 RecR protein 40 77 4.5E-15 T 28-03-2018 IPR023628 Recombination protein RecR, C4-type zinc finger CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 Gene3D G3DSA:1.10.150.20 7 30 0.22 T 28-03-2018 CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 Hamap MF_00017 Recombination protein RecR [recR]. 1 197 100.566 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 Gene3D G3DSA:3.40.1360.10 76 169 2.1E-37 T 28-03-2018 CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 SUPERFAMILY SSF111304 1 197 4.58E-70 T 28-03-2018 IPR023627 Recombination protein RecR CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 SMART SM00493 79 163 1.4E-15 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 ProSitePatterns PS01300 RecR protein signature. 56 77 - T 28-03-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 Pfam PF13662 Toprim domain 81 170 3.9E-24 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS00935 2b30d0dda827e16dfbb136ae5d941570 197 TIGRFAM TIGR00615 recR: recombination protein RecR 2 195 5.1E-79 T 28-03-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 CNX65_RS21295 81dbfa6a59d93f3da3fbeac885008f58 609 SUPERFAMILY SSF52540 280 474 9.88E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21295 81dbfa6a59d93f3da3fbeac885008f58 609 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 296 322 1.9E-4 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS21295 81dbfa6a59d93f3da3fbeac885008f58 609 Gene3D G3DSA:3.40.50.300 18 181 0.001 T 28-03-2018 CNX65_RS21295 81dbfa6a59d93f3da3fbeac885008f58 609 Gene3D G3DSA:3.40.50.300 258 427 2.6E-8 T 28-03-2018 CNX65_RS21295 81dbfa6a59d93f3da3fbeac885008f58 609 SUPERFAMILY SSF52540 40 228 5.87E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04480 56d35e59026c5c8a8af4bd5fe0b1a1c5 285 SUPERFAMILY SSF55729 139 279 1.56E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS04480 56d35e59026c5c8a8af4bd5fe0b1a1c5 285 Gene3D G3DSA:3.40.630.30 125 281 1.6E-15 T 28-03-2018 CNX65_RS00965 793b1b69a6e0a265cef12ab9fbd2db5b 561 Gene3D G3DSA:3.90.76.10 54 220 8.8E-34 T 28-03-2018 CNX65_RS00965 793b1b69a6e0a265cef12ab9fbd2db5b 561 Gene3D G3DSA:3.10.105.10 323 533 4.6E-43 T 28-03-2018 CNX65_RS00965 793b1b69a6e0a265cef12ab9fbd2db5b 561 SUPERFAMILY SSF53850 45 557 4.89E-114 T 28-03-2018 CNX65_RS00965 793b1b69a6e0a265cef12ab9fbd2db5b 561 Gene3D G3DSA:3.40.190.10 223 322 2.8E-28 T 28-03-2018 CNX65_RS00965 793b1b69a6e0a265cef12ab9fbd2db5b 561 PIRSF PIRSF002741 5 560 6.5E-97 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS00965 793b1b69a6e0a265cef12ab9fbd2db5b 561 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 478 2.0E-80 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 303 316 4.4E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 279 295 4.4E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 229 242 4.4E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 196 207 4.4E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 PRINTS PR00980 Alanyl-tRNA synthetase signature 69 80 4.4E-26 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 Gene3D G3DSA:3.30.930.10 1 245 3.9E-97 T 28-03-2018 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 SUPERFAMILY SSF55681 2 248 1.66E-88 T 28-03-2018 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 Pfam PF02272 DHHA1 domain 740 881 1.4E-21 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 SUPERFAMILY SSF55186 559 720 2.35E-40 T 28-03-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain GO:0000166 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 SUPERFAMILY SSF101353 249 464 9.81E-55 T 28-03-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 Pfam PF01411 tRNA synthetases class II (A) 5 562 7.9E-194 T 28-03-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 SUPERFAMILY SSF50447 460 559 9.19E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 660 704 6.6E-14 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 887 164.166 T 28-03-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 5 866 6.0E-246 T 28-03-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 SMART SM00863 660 704 1.5E-16 T 28-03-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0005524|GO:0016876|GO:0043039 CNX65_RS26205 0aa0e4e842a4465e93b83af0db1a8b76 890 Gene3D G3DSA:3.30.980.10 560 721 2.1E-34 T 28-03-2018 CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 Pfam PF00271 Helicase conserved C-terminal domain 800 920 1.9E-7 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 SUPERFAMILY SSF46785 950 1029 3.26E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 SMART SM00490 839 920 2.9E-11 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 Pfam PF00270 DEAD/DEAH box helicase 587 747 8.0E-21 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 Gene3D G3DSA:3.40.50.300 566 768 4.3E-34 T 28-03-2018 CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 SMART SM00487 581 772 3.1E-22 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 Gene3D G3DSA:3.40.50.300 778 977 1.6E-18 T 28-03-2018 CNX65_RS12855 734bdc4818b6a3fa5369015d53ff6b9a 1355 SUPERFAMILY SSF52540 594 935 3.96E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 Gene3D G3DSA:1.10.40.30 388 454 4.7E-13 T 28-03-2018 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00149 Fumarate lyase superfamily signature 154 172 4.2E-18 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00149 Fumarate lyase superfamily signature 243 270 4.2E-18 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00149 Fumarate lyase superfamily signature 109 127 4.2E-18 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00149 Fumarate lyase superfamily signature 288 304 4.2E-18 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 TIGRFAM TIGR02426 protocat_pcaB: 3-carboxy-cis,cis-muconate cycloisomerase 16 361 7.7E-109 T 28-03-2018 IPR012789 3-carboxy-cis,cis-muconate cycloisomerase GO:0019619|GO:0047472 KEGG: 00362+5.5.1.2 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00145 Argininosuccinate lyase family signature 243 267 1.5E-8 T 28-03-2018 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00145 Argininosuccinate lyase family signature 149 169 1.5E-8 T 28-03-2018 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00145 Argininosuccinate lyase family signature 288 304 1.5E-8 T 28-03-2018 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00145 Argininosuccinate lyase family signature 108 130 1.5E-8 T 28-03-2018 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 PRINTS PR00145 Argininosuccinate lyase family signature 198 214 1.5E-8 T 28-03-2018 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 SMART SM00998 376 454 0.0095 T 28-03-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 Gene3D G3DSA:1.10.275.10 1 113 4.8E-14 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 Gene3D G3DSA:1.20.200.10 126 387 2.3E-90 T 28-03-2018 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 SUPERFAMILY SSF48557 11 459 1.88E-92 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CNX65_RS23220 946e9f18448a034a8727ae26f8530125 464 Pfam PF00206 Lyase 29 311 4.2E-39 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CNX65_RS17645 21edd13d338da89415f4753049564e5b 405 Gene3D G3DSA:1.10.443.10 191 391 1.1E-29 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS17645 21edd13d338da89415f4753049564e5b 405 Gene3D G3DSA:1.10.150.130 27 180 4.6E-13 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS17645 21edd13d338da89415f4753049564e5b 405 SUPERFAMILY SSF56349 125 390 5.0E-35 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS17645 21edd13d338da89415f4753049564e5b 405 Pfam PF00589 Phage integrase family 196 382 1.5E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS03435 2d59c9afd4ca83ca7da3a5375a54224b 356 Pfam PF00881 Nitroreductase family 168 348 1.1E-16 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS03435 2d59c9afd4ca83ca7da3a5375a54224b 356 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 183 352 1.1E-32 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain CNX65_RS03435 2d59c9afd4ca83ca7da3a5375a54224b 356 Gene3D G3DSA:3.40.109.10 99 352 2.7E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS03435 2d59c9afd4ca83ca7da3a5375a54224b 356 SUPERFAMILY SSF55469 164 227 5.97E-21 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS03435 2d59c9afd4ca83ca7da3a5375a54224b 356 SUPERFAMILY SSF55469 255 352 5.97E-21 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 Pfam PF01494 FAD binding domain 7 308 2.2E-16 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 5 27 3.0E-13 T 28-03-2018 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 3.0E-13 T 28-03-2018 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 303 3.0E-13 T 28-03-2018 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 272 287 3.0E-13 T 28-03-2018 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 Gene3D G3DSA:3.50.50.60 2 362 3.6E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 SUPERFAMILY SSF51905 259 364 4.97E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10405 f719e5ef3758b31e0b07c01aa5c6facb 388 SUPERFAMILY SSF51905 5 167 4.97E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06850 7c4d586ba7feb4a9ec01bfc03aeb5c9c 126 Gene3D G3DSA:3.30.530.20 3 52 1.6E-7 T 28-03-2018 IPR023393 START-like domain CNX65_RS06850 7c4d586ba7feb4a9ec01bfc03aeb5c9c 126 SUPERFAMILY SSF55961 5 92 5.79E-8 T 28-03-2018 CNX65_RS06850 7c4d586ba7feb4a9ec01bfc03aeb5c9c 126 Gene3D G3DSA:3.30.530.20 53 121 0.012 T 28-03-2018 IPR023393 START-like domain CNX65_RS10580 305788721ebed6a97116ecf93ce3ae7e 373 Pfam PF11991 Tryptophan dimethylallyltransferase 65 243 8.2E-12 T 28-03-2018 IPR017795 Aromatic prenyltransferase, DMATS-type GO:0009820|GO:0016765 CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 Gene3D G3DSA:3.40.50.2300 9 143 6.3E-36 T 28-03-2018 CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 SMART SM00448 21 132 3.2E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 SUPERFAMILY SSF46894 146 243 2.24E-28 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 SMART SM00862 168 242 3.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 Gene3D G3DSA:1.10.10.10 144 246 3.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 Pfam PF00072 Response regulator receiver domain 23 132 8.0E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 SUPERFAMILY SSF52172 16 141 4.7E-40 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS08600 9ebd576cbc33cdc13b432d977f83e9f9 246 Pfam PF00486 Transcriptional regulatory protein, C terminal 169 242 7.5E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS34505 d196ec4f57bfd8f5b2e2f0d1fc30eb2c 397 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 41 384 2.9E-129 T 28-03-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 CNX65_RS34505 d196ec4f57bfd8f5b2e2f0d1fc30eb2c 397 SUPERFAMILY SSF52518 38 387 4.42E-94 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS34505 d196ec4f57bfd8f5b2e2f0d1fc30eb2c 397 Gene3D G3DSA:3.40.50.970 12 385 1.2E-90 T 28-03-2018 CNX65_RS34505 d196ec4f57bfd8f5b2e2f0d1fc30eb2c 397 Pfam PF00676 Dehydrogenase E1 component 71 345 5.4E-73 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CNX65_RS25675 61902ffef87651c87d607b07e6b0fe16 303 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS25675 61902ffef87651c87d607b07e6b0fe16 303 Gene3D G3DSA:3.40.50.300 1 235 3.6E-55 T 28-03-2018 CNX65_RS25675 61902ffef87651c87d607b07e6b0fe16 303 Pfam PF00005 ABC transporter 17 155 9.7E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS25675 61902ffef87651c87d607b07e6b0fe16 303 SUPERFAMILY SSF52540 1 218 3.93E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25675 61902ffef87651c87d607b07e6b0fe16 303 SMART SM00382 25 203 3.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 Gene3D G3DSA:1.25.40.10 158 208 1.9E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 Gene3D G3DSA:1.25.40.10 2 89 5.5E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 Gene3D G3DSA:1.25.40.10 90 157 7.2E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 Pfam PF13432 Tetratricopeptide repeat 148 189 2.5E-4 T 28-03-2018 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 Pfam PF13432 Tetratricopeptide repeat 23 69 0.002 T 28-03-2018 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 SMART SM00028 5 38 300.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 SMART SM00028 39 72 0.057 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 SMART SM00028 73 106 39.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 SMART SM00028 142 175 0.0063 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS05375 12513df06ffdd0d26322295eb3564988 331 SUPERFAMILY SSF48452 11 191 2.03E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS34250 64c804f6edc25ccc8b896537216d13d7 371 Pfam PF03663 Glycosyl hydrolase family 76 53 328 1.3E-31 T 28-03-2018 IPR005198 Glycoside hydrolase, family 76 KEGG: 00052+3.2.1.10|KEGG: 00500+3.2.1.10 CNX65_RS34250 64c804f6edc25ccc8b896537216d13d7 371 Gene3D G3DSA:1.50.10.20 5 364 2.2E-51 T 28-03-2018 CNX65_RS34250 64c804f6edc25ccc8b896537216d13d7 371 SUPERFAMILY SSF48208 26 310 1.02E-24 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS29265 dbbe147f0780f41992be915a7a2157e2 226 SMART SM00862 148 224 6.9E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS29265 dbbe147f0780f41992be915a7a2157e2 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 4.3E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS29265 dbbe147f0780f41992be915a7a2157e2 226 Gene3D G3DSA:1.10.10.10 119 226 4.6E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29265 dbbe147f0780f41992be915a7a2157e2 226 SUPERFAMILY SSF52172 1 183 2.13E-41 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS29265 dbbe147f0780f41992be915a7a2157e2 226 SMART SM00448 2 112 2.2E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS29265 dbbe147f0780f41992be915a7a2157e2 226 Pfam PF00072 Response regulator receiver domain 4 112 2.6E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS29265 dbbe147f0780f41992be915a7a2157e2 226 Gene3D G3DSA:3.40.50.2300 1 118 5.2E-37 T 28-03-2018 CNX65_RS09210 6255bd290a378a425b0b39994dfd9686 295 SUPERFAMILY SSF161098 30 295 1.59E-69 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09210 6255bd290a378a425b0b39994dfd9686 295 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 288 5.9E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09210 6255bd290a378a425b0b39994dfd9686 295 Gene3D G3DSA:1.10.3720.10 22 282 1.9E-41 T 28-03-2018 CNX65_RS16435 6f05b14e55a60407df5c080434319c61 183 Pfam PF04892 VanZ like family 97 165 3.8E-10 T 28-03-2018 IPR006976 VanZ-like CNX65_RS30415 f72f0b0c5604d905e6934e60fc74b4d7 375 SUPERFAMILY SSF55469 165 226 4.85E-21 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS30415 f72f0b0c5604d905e6934e60fc74b4d7 375 SUPERFAMILY SSF55469 264 371 4.85E-21 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS30415 f72f0b0c5604d905e6934e60fc74b4d7 375 Pfam PF00881 Nitroreductase family 169 352 3.5E-18 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS30415 f72f0b0c5604d905e6934e60fc74b4d7 375 TIGRFAM TIGR03605 antibiot_sagB: SagB-type dehydrogenase domain 184 349 8.4E-30 T 28-03-2018 IPR020051 SagB-type dehydrogenase domain CNX65_RS30415 f72f0b0c5604d905e6934e60fc74b4d7 375 Gene3D G3DSA:3.40.109.10 103 354 2.2E-38 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS13425 ee9c7f4873cde4b24ff7cb3596f0c8d3 567 SUPERFAMILY SSF101473 362 563 3.27E-41 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS13425 ee9c7f4873cde4b24ff7cb3596f0c8d3 567 Gene3D G3DSA:3.40.50.10440 12 182 3.9E-51 T 28-03-2018 CNX65_RS13425 ee9c7f4873cde4b24ff7cb3596f0c8d3 567 SUPERFAMILY SSF82549 11 328 4.97E-101 T 28-03-2018 CNX65_RS13425 ee9c7f4873cde4b24ff7cb3596f0c8d3 567 Pfam PF02733 Dak1 domain 18 325 9.2E-105 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS13425 ee9c7f4873cde4b24ff7cb3596f0c8d3 567 SMART SM01120 391 562 1.3E-45 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS13425 ee9c7f4873cde4b24ff7cb3596f0c8d3 567 Pfam PF02734 DAK2 domain 392 561 7.0E-38 T 28-03-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS13425 ee9c7f4873cde4b24ff7cb3596f0c8d3 567 Gene3D G3DSA:3.30.1180.20 183 331 1.7E-42 T 28-03-2018 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 SUPERFAMILY SSF48264 41 418 3.14E-83 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 Pfam PF00067 Cytochrome P450 241 390 5.1E-17 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00385 P450 superfamily signature 369 380 2.7E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00385 P450 superfamily signature 261 278 2.7E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00385 P450 superfamily signature 296 307 2.7E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00385 P450 superfamily signature 360 369 2.7E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 362 371 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00359 B-class P450 signature 116 127 4.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00359 B-class P450 signature 217 239 4.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00359 B-class P450 signature 314 341 4.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00359 B-class P450 signature 296 307 4.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00359 B-class P450 signature 180 195 4.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00359 B-class P450 signature 369 380 4.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 PRINTS PR00359 B-class P450 signature 163 179 4.8E-47 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS12835 97e2bd71cc23839afebe3036e6136697 419 Gene3D G3DSA:1.10.630.10 30 418 1.1E-65 T 28-03-2018 CNX65_RS24525 e429eadf3cf822754e2654cdc55014ba 389 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 274 356 1.9E-9 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CNX65_RS24525 e429eadf3cf822754e2654cdc55014ba 389 SUPERFAMILY SSF53756 3 386 1.61E-69 T 28-03-2018 CNX65_RS24525 e429eadf3cf822754e2654cdc55014ba 389 TIGRFAM TIGR01426 MGT: glycosyltransferase, MGT family 222 373 1.1E-35 T 28-03-2018 IPR006326 UDP-glycosyltransferase, MGT GO:0016758|GO:0016999 CNX65_RS24525 e429eadf3cf822754e2654cdc55014ba 389 Gene3D G3DSA:3.40.50.2000 3 212 1.3E-27 T 28-03-2018 CNX65_RS24525 e429eadf3cf822754e2654cdc55014ba 389 Gene3D G3DSA:3.40.50.2000 213 373 9.6E-38 T 28-03-2018 CNX65_RS07830 9d9bc64f5e8a89ff97b2b9ff939ec145 358 SUPERFAMILY SSF56091 6 199 5.14E-38 T 28-03-2018 CNX65_RS07830 9d9bc64f5e8a89ff97b2b9ff939ec145 358 Pfam PF04679 ATP dependent DNA ligase C terminal region 221 328 1.4E-15 T 28-03-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 CNX65_RS07830 9d9bc64f5e8a89ff97b2b9ff939ec145 358 Gene3D G3DSA:3.30.470.30 27 139 6.3E-27 T 28-03-2018 CNX65_RS07830 9d9bc64f5e8a89ff97b2b9ff939ec145 358 Gene3D G3DSA:2.40.50.140 200 345 5.2E-27 T 28-03-2018 CNX65_RS07830 9d9bc64f5e8a89ff97b2b9ff939ec145 358 Pfam PF01068 ATP dependent DNA ligase domain 11 199 1.4E-28 T 28-03-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 CNX65_RS07830 9d9bc64f5e8a89ff97b2b9ff939ec145 358 Gene3D G3DSA:3.30.1490.70 140 199 1.4E-9 T 28-03-2018 CNX65_RS07830 9d9bc64f5e8a89ff97b2b9ff939ec145 358 SUPERFAMILY SSF50249 202 334 3.94E-12 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 Pfam PF01037 Lrp/AsnC ligand binding domain 68 137 1.5E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 SUPERFAMILY SSF46785 2 67 6.92E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.6E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.6E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.6E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 Gene3D G3DSA:1.10.10.10 1 50 5.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 SUPERFAMILY SSF54909 61 143 7.11E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 SMART SM00344 1 108 2.7E-36 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 Pfam PF13412 Winged helix-turn-helix DNA-binding 2 48 1.2E-17 T 28-03-2018 CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 Gene3D G3DSA:3.30.70.920 51 143 9.3E-18 T 28-03-2018 CNX65_RS11500 a7fa61ce71b08f0e0fcc028f789f2f4c 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CNX65_RS30670 c376a27cfb896331a196b41bb0bcead0 197 Gene3D G3DSA:1.10.357.10 58 191 2.6E-22 T 28-03-2018 CNX65_RS30670 c376a27cfb896331a196b41bb0bcead0 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS30670 c376a27cfb896331a196b41bb0bcead0 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS30670 c376a27cfb896331a196b41bb0bcead0 197 Gene3D G3DSA:1.10.10.60 2 57 1.3E-20 T 28-03-2018 CNX65_RS30670 c376a27cfb896331a196b41bb0bcead0 197 SUPERFAMILY SSF46689 5 84 3.26E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS30670 c376a27cfb896331a196b41bb0bcead0 197 SUPERFAMILY SSF48498 80 185 4.45E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS30670 c376a27cfb896331a196b41bb0bcead0 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 5.9E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11050 e53351594a3db61301d93f70f782484a 122 Pfam PF02810 SEC-C motif 3 17 6.3E-5 T 28-03-2018 IPR004027 SEC-C motif CNX65_RS11050 e53351594a3db61301d93f70f782484a 122 SUPERFAMILY SSF54427 22 119 2.45E-33 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS11050 e53351594a3db61301d93f70f782484a 122 Gene3D G3DSA:3.10.450.50 1 121 3.9E-42 T 28-03-2018 CNX65_RS02125 c201bc2371c501790b1980e725287971 217 Gene3D G3DSA:1.10.357.10 75 217 1.3E-18 T 28-03-2018 CNX65_RS02125 c201bc2371c501790b1980e725287971 217 SUPERFAMILY SSF46689 23 99 1.1E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS02125 c201bc2371c501790b1980e725287971 217 SUPERFAMILY SSF48498 101 215 6.82E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS02125 c201bc2371c501790b1980e725287971 217 Pfam PF00440 Bacterial regulatory proteins, tetR family 34 79 2.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02125 c201bc2371c501790b1980e725287971 217 Gene3D G3DSA:1.10.10.60 6 74 4.3E-15 T 28-03-2018 CNX65_RS02125 c201bc2371c501790b1980e725287971 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 54 77 2.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02125 c201bc2371c501790b1980e725287971 217 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 46 2.4E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21265 26cc82f06decbbd5dd1fc71fd36727ab 287 Gene3D G3DSA:1.10.260.40 1 87 8.8E-16 T 28-03-2018 CNX65_RS21265 26cc82f06decbbd5dd1fc71fd36727ab 287 SUPERFAMILY SSF47413 29 80 1.36E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS21265 26cc82f06decbbd5dd1fc71fd36727ab 287 Pfam PF13560 Helix-turn-helix domain 5 84 3.9E-16 T 28-03-2018 CNX65_RS21265 26cc82f06decbbd5dd1fc71fd36727ab 287 SMART SM00530 9 81 1.6E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 Gene3D G3DSA:3.40.50.1820 13 285 1.2E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 Gene3D G3DSA:2.60.40.290 292 422 1.4E-33 T 28-03-2018 CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 SUPERFAMILY SSF53474 15 96 2.84E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 SMART SM00637 323 422 5.9E-46 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 Pfam PF00553 Cellulose binding domain 323 422 1.0E-31 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 TIGRFAM TIGR01840 esterase_phb: esterase, PHB depolymerase family 38 248 1.4E-43 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 SUPERFAMILY SSF53474 121 323 1.28E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 Pfam PF10503 Esterase PHB depolymerase 38 241 2.2E-21 T 28-03-2018 IPR010126 Esterase, PHB depolymerase GO:0005576|GO:0016787 CNX65_RS19805 ce23e73a42437b027e020c4cdba5ee5f 425 SUPERFAMILY SSF49384 318 423 1.12E-32 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 SUPERFAMILY SSF46785 33 98 1.22E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 Gene3D G3DSA:1.10.10.10 5 95 1.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 SUPERFAMILY SSF53383 112 465 7.01E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 SMART SM00345 35 94 3.7E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 Gene3D G3DSA:3.90.1150.10 379 471 4.0E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 68 84 5.6E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 54 68 5.6E-8 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 Gene3D G3DSA:3.40.640.10 129 378 1.9E-45 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 Pfam PF00392 Bacterial regulatory proteins, gntR family 34 93 1.1E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS33465 4ceb16783e394dd0ae7b01484a068448 487 Pfam PF00155 Aminotransferase class I and II 152 464 6.6E-30 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS13810 dbcc5cda7630ecd42f7468cfb1f29c4a 77 Pfam PF00550 Phosphopantetheine attachment site 9 73 6.7E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13810 dbcc5cda7630ecd42f7468cfb1f29c4a 77 SUPERFAMILY SSF47336 6 76 1.14E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13810 dbcc5cda7630ecd42f7468cfb1f29c4a 77 Gene3D G3DSA:1.10.1200.10 2 77 6.9E-14 T 28-03-2018 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 SMART SM01240 17 489 0.0 T 28-03-2018 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 SMART SM00116 167 215 2.0E-7 T 28-03-2018 IPR000644 CBS domain CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 SMART SM00116 106 154 6.1E-9 T 28-03-2018 IPR000644 CBS domain CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 SUPERFAMILY SSF51412 13 100 2.88E-114 T 28-03-2018 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 SUPERFAMILY SSF51412 226 493 2.88E-114 T 28-03-2018 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 18 502 82.932 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 PIRSF PIRSF000130 9 503 8.5E-199 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 18 489 9.6E-154 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 18 471 9.0E-185 T 28-03-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00053+1.1.1.20|KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 SUPERFAMILY SSF54631 73 212 7.42E-30 T 28-03-2018 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 305 317 - T 28-03-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 Gene3D G3DSA:3.20.20.70 10 488 6.8E-109 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 Pfam PF00571 CBS domain 103 152 2.5E-10 T 28-03-2018 IPR000644 CBS domain CNX65_RS32065 4abd0f571f0f7b0db34fc8c9c5ed0791 503 Pfam PF00571 CBS domain 159 212 1.1E-7 T 28-03-2018 IPR000644 CBS domain CNX65_RS04855 39ceb920e9483856ee3fd81d1fa83619 524 Gene3D G3DSA:3.60.40.10 278 518 5.0E-21 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS04855 39ceb920e9483856ee3fd81d1fa83619 524 Gene3D G3DSA:3.30.450.40 100 277 1.3E-5 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS04855 39ceb920e9483856ee3fd81d1fa83619 524 SMART SM00331 297 517 3.6E-4 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS04855 39ceb920e9483856ee3fd81d1fa83619 524 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 326 517 1.2E-23 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18245 aa0a9c9aab70842077fb23bea626a6b6 175 Pfam PF00720 Subtilisin inhibitor-like 86 159 9.7E-13 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS18245 aa0a9c9aab70842077fb23bea626a6b6 175 SUPERFAMILY SSF55399 80 175 3.14E-15 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS18245 aa0a9c9aab70842077fb23bea626a6b6 175 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 82 165 7.0E-8 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS18245 aa0a9c9aab70842077fb23bea626a6b6 175 Gene3D G3DSA:3.30.350.10 74 175 2.8E-20 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS05500 2eb82b3839fb3a456edb192982b56be6 316 Gene3D G3DSA:3.10.25.10 205 313 1.8E-19 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS05500 2eb82b3839fb3a456edb192982b56be6 316 SUPERFAMILY SSF50486 205 307 1.33E-16 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CNX65_RS05500 2eb82b3839fb3a456edb192982b56be6 316 Pfam PF02911 Formyl transferase, C-terminal domain 205 305 3.9E-15 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS05500 2eb82b3839fb3a456edb192982b56be6 316 Pfam PF00551 Formyl transferase 1 167 1.2E-29 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS05500 2eb82b3839fb3a456edb192982b56be6 316 SUPERFAMILY SSF53328 1 203 3.53E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS05500 2eb82b3839fb3a456edb192982b56be6 316 Gene3D G3DSA:3.40.50.170 1 204 2.9E-54 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS17925 ced33594e0512080ed81d435a5ddb4b4 328 Gene3D G3DSA:3.40.190.10 172 254 6.0E-12 T 28-03-2018 CNX65_RS17925 ced33594e0512080ed81d435a5ddb4b4 328 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 68 275 1.4E-30 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS17925 ced33594e0512080ed81d435a5ddb4b4 328 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 91 104 - T 28-03-2018 IPR018313 Solute-binding protein family 3, conserved site GO:0005215|GO:0006810 CNX65_RS17925 ced33594e0512080ed81d435a5ddb4b4 328 SMART SM00062 67 296 1.5E-18 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS17925 ced33594e0512080ed81d435a5ddb4b4 328 Gene3D G3DSA:3.40.190.10 58 171 1.1E-17 T 28-03-2018 CNX65_RS17925 ced33594e0512080ed81d435a5ddb4b4 328 SUPERFAMILY SSF53850 64 275 2.37E-29 T 28-03-2018 CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 755 795 5.7E-10 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1171 1207 4.6E-7 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 629 669 2.1E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 545 580 4.3E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 712 752 7.8E-11 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 859 900 3.5E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 566 594 0.0021 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 670 708 6.7E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 901 938 6.3E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 963 1001 1.8E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 817 857 1.1E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF15657 HNH/Endo VII superfamily nuclease toxins 1402 1469 2.2E-14 T 28-03-2018 IPR028048 HNH/Endo VII superfamily nuclease toxins CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF05593 RHS Repeat 654 686 2.0E-8 T 28-03-2018 IPR031325 RHS repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF05593 RHS Repeat 755 791 1.6E-9 T 28-03-2018 IPR031325 RHS repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF05593 RHS Repeat 566 598 7.8E-5 T 28-03-2018 IPR031325 RHS repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF05593 RHS Repeat 1171 1201 1.0E-6 T 28-03-2018 IPR031325 RHS repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF05593 RHS Repeat 963 997 1.1E-5 T 28-03-2018 IPR031325 RHS repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF05593 RHS Repeat 712 748 9.2E-10 T 28-03-2018 IPR031325 RHS repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF05593 RHS Repeat 859 896 3.9E-6 T 28-03-2018 IPR031325 RHS repeat CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Gene3D G3DSA:1.10.287.850 73 241 2.3E-6 T 28-03-2018 CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 1287 1360 5.7E-22 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS22580 b49cbac11b053e39de619f0774de36f8 1480 Pfam PF03527 RHS protein 1264 1294 2.6E-7 T 28-03-2018 IPR001826 RHS protein CNX65_RS34955 ac91b48ff050020c51aad729a129a68c 439 Gene3D G3DSA:1.20.1250.20 235 431 4.3E-12 T 28-03-2018 CNX65_RS34955 ac91b48ff050020c51aad729a129a68c 439 Gene3D G3DSA:1.20.1250.20 8 218 4.1E-12 T 28-03-2018 CNX65_RS34955 ac91b48ff050020c51aad729a129a68c 439 Pfam PF07690 Major Facilitator Superfamily 57 392 6.1E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS34955 ac91b48ff050020c51aad729a129a68c 439 SUPERFAMILY SSF103473 56 428 5.75E-24 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS02060 e0f0ebf28c8373e24c4d39e8f4dca61e 273 SUPERFAMILY SSF161098 4 273 5.51E-77 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02060 e0f0ebf28c8373e24c4d39e8f4dca61e 273 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 260 8.8E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02060 e0f0ebf28c8373e24c4d39e8f4dca61e 273 Gene3D G3DSA:1.10.3720.10 1 260 4.0E-49 T 28-03-2018 CNX65_RS19710 049311d7c30ced47bd0ea69b8e550bd8 206 SUPERFAMILY SSF53597 5 204 7.07E-24 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS19710 049311d7c30ced47bd0ea69b8e550bd8 206 Pfam PF01872 RibD C-terminal domain 4 191 3.5E-17 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS19710 049311d7c30ced47bd0ea69b8e550bd8 206 Gene3D G3DSA:3.40.430.10 4 204 1.3E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS13380 054df954e9118f36ecf5cf2e0a5cf510 477 SUPERFAMILY SSF51905 1 295 1.2E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13380 054df954e9118f36ecf5cf2e0a5cf510 477 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 62 4.3E-8 T 28-03-2018 CNX65_RS13380 054df954e9118f36ecf5cf2e0a5cf510 477 Gene3D G3DSA:3.50.50.60 166 454 2.8E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13380 054df954e9118f36ecf5cf2e0a5cf510 477 SUPERFAMILY SSF51905 175 222 5.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13380 054df954e9118f36ecf5cf2e0a5cf510 477 SUPERFAMILY SSF51905 296 403 5.4E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13380 054df954e9118f36ecf5cf2e0a5cf510 477 Pfam PF00743 Flavin-binding monooxygenase-like 82 213 9.7E-10 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS13380 054df954e9118f36ecf5cf2e0a5cf510 477 Gene3D G3DSA:3.50.50.60 4 165 1.6E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 Gene3D G3DSA:1.10.10.10 126 207 2.5E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 SMART SM00421 145 202 5.8E-25 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 ProSitePatterns PS00622 LuxR-type HTH domain signature. 162 189 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 Pfam PF00072 Response regulator receiver domain 3 115 5.8E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 Gene3D G3DSA:3.40.50.2300 1 125 1.7E-30 T 28-03-2018 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 SUPERFAMILY SSF52172 1 132 7.4E-30 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 Pfam PF00196 Bacterial regulatory proteins, luxR family 147 201 1.8E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 178 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 178 190 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 148 162 1.1E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 SUPERFAMILY SSF46894 137 206 1.8E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS00490 10c32d4a94eadc1c503a81119e615e43 207 SMART SM00448 1 114 1.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 Pfam PF00175 Oxidoreductase NAD-binding domain 328 424 2.1E-7 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 Pfam PF01794 Ferric reductase like transmembrane component 53 175 3.4E-13 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 SUPERFAMILY SSF52343 307 441 5.89E-24 T 28-03-2018 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 Gene3D G3DSA:3.40.50.80 316 447 4.2E-20 T 28-03-2018 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 Gene3D G3DSA:2.40.30.10 217 315 2.4E-15 T 28-03-2018 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 Pfam PF08022 FAD-binding domain 225 315 1.6E-4 T 28-03-2018 IPR013112 FAD-binding 8 GO:0016491|GO:0055114 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 SUPERFAMILY SSF63380 217 316 2.69E-15 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 PRINTS PR00410 Phenol hydroxylase reductase family signature 311 320 2.4E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 PRINTS PR00410 Phenol hydroxylase reductase family signature 411 419 2.4E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CNX65_RS01950 0eb355c7fefc2e02b20b45a6c58e9078 447 PRINTS PR00410 Phenol hydroxylase reductase family signature 327 346 2.4E-6 T 28-03-2018 IPR001221 Phenol hydroxylase reductase GO:0055114 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF56801 1461 1966 6.67E-133 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:2.30.38.10 753 836 2.2E-23 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:2.30.38.10 1757 1844 4.6E-23 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:2.30.38.10 2768 2855 1.1E-23 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF13193 AMP-binding enzyme C-terminal domain 2871 2937 7.2E-8 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF13193 AMP-binding enzyme C-terminal domain 1860 1927 9.2E-9 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF13193 AMP-binding enzyme C-terminal domain 852 918 1.1E-10 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF52777 191 425 3.45E-45 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 ProSitePatterns PS00012 Phosphopantetheine attachment site. 966 981 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF52777 1195 1433 1.45E-44 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00501 AMP-binding enzyme 1468 1852 1.2E-86 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00501 AMP-binding enzyme 2483 2863 4.4E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00501 AMP-binding enzyme 462 844 6.9E-85 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00668 Condensation domain 2043 2459 2.9E-61 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00668 Condensation domain 30 440 5.9E-49 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00668 Condensation domain 1031 1444 2.6E-65 T 28-03-2018 IPR001242 Condensation domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.30.559.10 2020 2217 4.2E-29 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.30.559.10 1015 1201 1.4E-38 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 ProSitePatterns PS00455 Putative AMP-binding domain signature. 2616 2627 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.40.50.980 1611 1756 8.5E-26 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.40.50.980 2622 2767 2.5E-24 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF52777 2211 2449 1.22E-47 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.40.50.980 596 752 5.9E-33 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 482 868 9.1E-120 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 1488 1876 5.9E-121 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 2503 2887 6.7E-118 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.40.50.980 1458 1610 2.1E-43 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.40.50.980 2473 2621 1.8E-47 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF47336 2955 3026 7.2E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF52777 2046 2209 2.0E-35 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00550 Phosphopantetheine attachment site 944 1007 4.7E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00550 Phosphopantetheine attachment site 1956 2019 2.4E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Pfam PF00550 Phosphopantetheine attachment site 2963 3026 5.1E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF47336 935 1007 2.36E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:1.10.1200.10 950 1014 7.5E-22 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF56801 420 955 1.24E-137 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:1.10.1200.10 2968 3029 1.8E-22 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF56801 2475 2973 2.09E-137 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SMART SM00823 Phosphopantetheine attachment site 942 1011 4.2E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SMART SM00823 Phosphopantetheine attachment site 2961 3030 4.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SMART SM00823 Phosphopantetheine attachment site 1953 2024 8.5E-11 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF52777 32 198 2.17E-28 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 ProSitePatterns PS00012 Phosphopantetheine attachment site. 1979 1994 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.30.300.30 2858 2967 6.6E-30 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.30.300.30 839 949 3.7E-30 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.30.300.30 1847 1959 9.5E-32 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:1.10.1200.10 1960 2019 1.0E-21 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.40.50.980 454 595 3.0E-35 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF47336 1946 2020 8.38E-19 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 Gene3D G3DSA:3.30.559.10 8 208 2.4E-25 T 28-03-2018 CNX65_RS18345 24a5187563644eb15e8c86b24ee75c7f 3049 SUPERFAMILY SSF52777 1034 1192 7.34E-39 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Gene3D G3DSA:1.20.120.330 204 284 0.01 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Gene3D G3DSA:1.20.120.330 159 203 0.044 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 SUPERFAMILY SSF81891 335 567 3.14E-15 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 SUPERFAMILY SSF81593 186 278 1.65E-5 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 SUPERFAMILY SSF81301 29 155 3.35E-13 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Pfam PF01966 HD domain 429 515 3.1E-9 T 28-03-2018 IPR006674 HD domain CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Gene3D G3DSA:3.30.70.260 585 694 3.0E-13 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Gene3D G3DSA:3.30.70.260 710 782 2.8E-10 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 SUPERFAMILY SSF55021 607 676 3.27E-7 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Hamap MF_00277 Bifunctional uridylyltransferase/uridylyl-removing enzyme [glnD]. 1 782 67.238 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 SMART SM00471 424 557 1.4E-6 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Gene3D G3DSA:3.30.460.10 25 158 1.2E-8 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 PIRSF PIRSF006288 583 778 3.3E-29 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 PIRSF PIRSF006288 2 600 1.7E-144 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 TIGRFAM TIGR01693 UTase_glnD: protein-P-II uridylyltransferase 22 590 1.5E-161 T 28-03-2018 IPR010043 Bifunctional uridylyltransferase/uridylyl-removing enzyme GO:0006807|GO:0008773 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 Gene3D G3DSA:1.10.3090.10 329 584 2.5E-39 T 28-03-2018 CNX65_RS29120 ed23ff0dc013603cde67b8b0ae45c621 782 SUPERFAMILY SSF55021 714 771 2.17E-8 T 28-03-2018 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 5.6E-6 T 28-03-2018 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 117 126 5.6E-6 T 28-03-2018 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 Pfam PF05834 Lycopene cyclase protein 2 342 8.0E-52 T 28-03-2018 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 6.4E-5 T 28-03-2018 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 114 132 6.4E-5 T 28-03-2018 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 Gene3D G3DSA:3.50.50.60 1 328 4.9E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 SUPERFAMILY SSF51905 1 156 2.59E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS25585 b18e454ae3bf6d127a10fd3c7676bcc0 359 SUPERFAMILY SSF51905 217 284 2.59E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23140 2760c592623f1341da111ddd73f1241f 414 Pfam PF13520 Amino acid permease 10 391 2.6E-38 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS23140 2760c592623f1341da111ddd73f1241f 414 PIRSF PIRSF006060 1 407 2.7E-60 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS34420 a0570d0ad021dcdc3aff02c620beb8f8 876 Pfam PF04294 VanW like protein 668 799 1.8E-38 T 28-03-2018 IPR007391 Vancomycin resistance VanW CNX65_RS34420 a0570d0ad021dcdc3aff02c620beb8f8 876 Pfam PF12229 Putative peptidoglycan binding domain 544 629 3.7E-10 T 28-03-2018 IPR022029 Putative peptidoglycan binding domain CNX65_RS07140 36ef4325ea4a4f5b774a0e1fe738564e 237 Gene3D G3DSA:3.40.830.10 113 235 1.2E-17 T 28-03-2018 CNX65_RS07140 36ef4325ea4a4f5b774a0e1fe738564e 237 Gene3D G3DSA:3.40.830.10 1 112 6.4E-5 T 28-03-2018 CNX65_RS07140 36ef4325ea4a4f5b774a0e1fe738564e 237 SUPERFAMILY SSF53213 112 229 1.18E-8 T 28-03-2018 CNX65_RS22410 e20f15f4c3a84b323e1819bf6f94e0ed 71 SMART SM00923 2 52 7.0E-23 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS22410 e20f15f4c3a84b323e1819bf6f94e0ed 71 SUPERFAMILY SSF160582 3 69 2.22E-28 T 28-03-2018 CNX65_RS22410 e20f15f4c3a84b323e1819bf6f94e0ed 71 Gene3D G3DSA:3.90.820.10 2 67 9.8E-32 T 28-03-2018 CNX65_RS22410 e20f15f4c3a84b323e1819bf6f94e0ed 71 Pfam PF03621 MbtH-like protein 4 51 6.7E-23 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS13840 437a654707f8a7e2450c09151f858dd0 514 Gene3D G3DSA:3.40.50.1820 23 467 1.5E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13840 437a654707f8a7e2450c09151f858dd0 514 Pfam PF08386 TAP-like protein 396 487 2.0E-18 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS13840 437a654707f8a7e2450c09151f858dd0 514 SUPERFAMILY SSF53474 318 459 1.32E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13840 437a654707f8a7e2450c09151f858dd0 514 SUPERFAMILY SSF53474 74 134 1.32E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13840 437a654707f8a7e2450c09151f858dd0 514 SUPERFAMILY SSF53474 176 235 1.32E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13840 437a654707f8a7e2450c09151f858dd0 514 Pfam PF00561 alpha/beta hydrolase fold 89 281 3.1E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25635 cd63b71780b32906205308fa19ea210f 481 SUPERFAMILY SSF101960 47 478 1.96E-140 T 28-03-2018 CNX65_RS25635 cd63b71780b32906205308fa19ea210f 481 Pfam PF01458 Uncharacterized protein family (UPF0051) 227 452 5.1E-76 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CNX65_RS25635 cd63b71780b32906205308fa19ea210f 481 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 25 472 1.3E-220 T 28-03-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 CNX65_RS11135 69e7f847a5bbae882919bdca415d8cb6 344 Hamap MF_00323 Ferrochelatase [hemH]. 2 303 31.517 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CNX65_RS11135 69e7f847a5bbae882919bdca415d8cb6 344 SUPERFAMILY SSF53800 3 309 1.05E-82 T 28-03-2018 CNX65_RS11135 69e7f847a5bbae882919bdca415d8cb6 344 TIGRFAM TIGR00109 hemH: ferrochelatase 34 302 4.0E-42 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CNX65_RS11135 69e7f847a5bbae882919bdca415d8cb6 344 Gene3D G3DSA:3.40.50.1400 151 285 1.2E-46 T 28-03-2018 CNX65_RS11135 69e7f847a5bbae882919bdca415d8cb6 344 Gene3D G3DSA:3.40.50.1400 1 150 1.6E-28 T 28-03-2018 CNX65_RS11135 69e7f847a5bbae882919bdca415d8cb6 344 Pfam PF00762 Ferrochelatase 4 302 2.4E-95 T 28-03-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 CNX65_RS07375 142adaed691c6a238eda39b1fad7adbb 379 Gene3D G3DSA:3.20.20.70 233 374 6.2E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS07375 142adaed691c6a238eda39b1fad7adbb 379 SUPERFAMILY SSF82282 207 344 5.49E-5 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CNX65_RS07375 142adaed691c6a238eda39b1fad7adbb 379 SUPERFAMILY SSF82282 140 177 5.49E-5 T 28-03-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 CNX65_RS07375 142adaed691c6a238eda39b1fad7adbb 379 Gene3D G3DSA:3.20.20.80 74 218 1.7E-6 T 28-03-2018 CNX65_RS28430 00783aedb137d9bf6946e92449741a26 166 Gene3D G3DSA:3.40.630.30 5 148 7.7E-21 T 28-03-2018 CNX65_RS28430 00783aedb137d9bf6946e92449741a26 166 Pfam PF00583 Acetyltransferase (GNAT) family 43 110 3.7E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS28430 00783aedb137d9bf6946e92449741a26 166 SUPERFAMILY SSF55729 5 125 1.03E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS18875 e818f6e578197ce910bd87f080ac9acf 420 Pfam PF13347 MFS/sugar transport protein 11 410 3.5E-73 T 28-03-2018 CNX65_RS18875 e818f6e578197ce910bd87f080ac9acf 420 SUPERFAMILY SSF103473 7 409 7.85E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS18875 e818f6e578197ce910bd87f080ac9acf 420 Gene3D G3DSA:1.20.1250.20 2 196 1.6E-15 T 28-03-2018 CNX65_RS18875 e818f6e578197ce910bd87f080ac9acf 420 Gene3D G3DSA:1.20.1250.20 204 420 2.1E-18 T 28-03-2018 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Gene3D G3DSA:2.60.40.10 142 229 1.2E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 SUPERFAMILY SSF49384 39 140 8.37E-27 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 SUPERFAMILY SSF48208 338 974 3.29E-276 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Pfam PF00553 Cellulose binding domain 40 139 1.9E-28 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Gene3D G3DSA:2.60.40.290 31 139 4.3E-32 T 28-03-2018 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Gene3D G3DSA:2.60.40.10 235 332 9.6E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Gene3D G3DSA:4.10.870.10 890 951 3.1E-29 T 28-03-2018 IPR027390 Endoglucanase F, domain 3 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Gene3D G3DSA:1.50.10.10 340 514 4.1E-51 T 28-03-2018 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Gene3D G3DSA:1.50.10.10 535 889 1.4E-150 T 28-03-2018 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 554 581 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 696 719 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 742 768 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 797 817 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 626 645 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 367 392 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 393 410 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 509 533 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 PRINTS PR00844 Glycosyl hydrolase family 48 signature 906 934 4.2E-97 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 Pfam PF02011 Glycosyl hydrolase family 48 341 973 0.0 T 28-03-2018 IPR000556 Glycoside hydrolase, 48F GO:0004553|GO:0008810|GO:0030245 CNX65_RS11060 42369c7b2e9a3824d7eb90539a505c78 974 SMART SM00637 40 139 2.6E-38 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 Gene3D G3DSA:1.20.1250.20 29 220 4.0E-33 T 28-03-2018 CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 SUPERFAMILY SSF46785 531 654 9.6E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 Gene3D G3DSA:1.10.10.10 532 680 4.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 34 446 2.6E-77 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 SUPERFAMILY SSF103473 268 440 3.4E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 SUPERFAMILY SSF103473 482 514 3.4E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 SUPERFAMILY SSF103473 17 211 3.4E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 Gene3D G3DSA:1.20.1250.20 272 521 5.5E-31 T 28-03-2018 CNX65_RS24035 8d5047143c02c6f02be5d0858bddcc52 686 Pfam PF07690 Major Facilitator Superfamily 39 431 1.4E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS19335 91e1cb9aa9b23acbd2589b56fb257e94 488 Pfam PF00589 Phage integrase family 269 430 2.0E-11 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS19335 91e1cb9aa9b23acbd2589b56fb257e94 488 Gene3D G3DSA:1.10.150.130 141 250 7.0E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS19335 91e1cb9aa9b23acbd2589b56fb257e94 488 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 147 200 1.3E-9 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CNX65_RS19335 91e1cb9aa9b23acbd2589b56fb257e94 488 Gene3D G3DSA:1.10.443.10 251 433 9.7E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS19335 91e1cb9aa9b23acbd2589b56fb257e94 488 SUPERFAMILY SSF56349 147 434 1.85E-52 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS03545 911e3dfe9ce6933b5bfb689465d5699d 657 PIRSF PIRSF006402 1 657 7.3E-193 T 28-03-2018 IPR024705 Spermatogenesis-associated protein 20 CNX65_RS03545 911e3dfe9ce6933b5bfb689465d5699d 657 SUPERFAMILY SSF48208 189 521 2.38E-69 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS03545 911e3dfe9ce6933b5bfb689465d5699d 657 Pfam PF03190 Protein of unknown function, DUF255 2 163 3.1E-74 T 28-03-2018 IPR004879 Domain of unknown function DUF255 CNX65_RS03545 911e3dfe9ce6933b5bfb689465d5699d 657 Gene3D G3DSA:1.50.10.10 341 574 1.1E-28 T 28-03-2018 CNX65_RS03545 911e3dfe9ce6933b5bfb689465d5699d 657 Gene3D G3DSA:1.50.10.10 214 340 9.2E-27 T 28-03-2018 CNX65_RS03545 911e3dfe9ce6933b5bfb689465d5699d 657 Gene3D G3DSA:3.40.30.10 1 171 5.2E-31 T 28-03-2018 CNX65_RS03545 911e3dfe9ce6933b5bfb689465d5699d 657 SUPERFAMILY SSF52833 2 127 2.96E-30 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 SUPERFAMILY SSF50621 235 369 2.2E-45 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 Gene3D G3DSA:2.40.37.10 217 370 4.2E-64 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 TIGRFAM TIGR00492 alr: alanine racemase 10 368 8.3E-96 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 28-03-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 SMART SM01005 242 370 1.0E-56 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 Pfam PF01168 Alanine racemase, N-terminal domain 14 232 2.6E-68 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 SUPERFAMILY SSF51419 14 243 7.27E-65 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 Hamap MF_01201 Alanine racemase. 7 370 32.785 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 Gene3D G3DSA:3.20.20.10 9 216 4.6E-47 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 Pfam PF00842 Alanine racemase, C-terminal domain 242 369 1.6E-42 T 28-03-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 275 290 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 351 364 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 68 86 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 163 174 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 205 232 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 296 313 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 258 273 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 32 48 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS32175 6678d10833e3cb7eabe923754d4bf52c 370 PRINTS PR00992 Alanine racemase signature 129 141 2.0E-65 T 28-03-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 218 2.0E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 Pfam PF00072 Response regulator receiver domain 3 109 2.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 SUPERFAMILY SSF52172 2 117 1.42E-35 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 SMART SM00862 146 218 6.1E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 SUPERFAMILY SSF46894 122 219 1.84E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 Gene3D G3DSA:3.40.50.2300 1 119 6.2E-34 T 28-03-2018 CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 SMART SM00448 1 108 7.6E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS27930 5c67942d934253224c2a289302e6a79f 222 Gene3D G3DSA:1.10.10.10 120 222 1.8E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19670 49ee319a1062fdbb180cc8548b342a99 424 Pfam PF07690 Major Facilitator Superfamily 39 344 7.3E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS19670 49ee319a1062fdbb180cc8548b342a99 424 Gene3D G3DSA:1.20.1250.20 217 414 1.4E-15 T 28-03-2018 CNX65_RS19670 49ee319a1062fdbb180cc8548b342a99 424 SUPERFAMILY SSF103473 18 413 6.67E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19670 49ee319a1062fdbb180cc8548b342a99 424 Gene3D G3DSA:1.20.1250.20 16 213 6.9E-14 T 28-03-2018 CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 Pfam PF13307 Helicase C-terminal domain 498 655 1.3E-26 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 Gene3D G3DSA:3.40.50.300 22 431 1.2E-27 T 28-03-2018 CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 SUPERFAMILY SSF52540 191 262 2.8E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 SUPERFAMILY SSF52540 474 635 2.8E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 SUPERFAMILY SSF52540 38 90 2.8E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 SUPERFAMILY SSF52540 397 411 2.8E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 SMART SM00487 18 302 1.2E-4 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 Gene3D G3DSA:3.40.50.300 489 677 1.3E-7 T 28-03-2018 CNX65_RS04990 8590b3a5a41a2eb3f5773a2af703372c 677 SMART SM00491 513 642 3.2E-40 T 28-03-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 Gene3D G3DSA:3.40.50.720 52 253 3.5E-57 T 28-03-2018 CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 Gene3D G3DSA:3.40.50.720 1 51 8.4E-12 T 28-03-2018 CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 SUPERFAMILY SSF51735 6 247 2.95E-79 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 6.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 6.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 6.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 211 231 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.4E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS10620 65ee5c328489af349558b013af1a625a 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 248 1.1E-68 T 28-03-2018 CNX65_RS14365 ffe4b9a43d36d4363023d4919f44764d 527 SUPERFAMILY SSF55031 204 309 2.09E-27 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS14365 ffe4b9a43d36d4363023d4919f44764d 527 Pfam PF01546 Peptidase family M20/M25/M40 90 408 9.8E-26 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS14365 ffe4b9a43d36d4363023d4919f44764d 527 SUPERFAMILY SSF53187 28 216 4.4E-69 T 28-03-2018 CNX65_RS14365 ffe4b9a43d36d4363023d4919f44764d 527 SUPERFAMILY SSF53187 317 412 4.4E-69 T 28-03-2018 CNX65_RS14365 ffe4b9a43d36d4363023d4919f44764d 527 Pfam PF07687 Peptidase dimerisation domain 205 299 3.8E-11 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS14365 ffe4b9a43d36d4363023d4919f44764d 527 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 32 394 2.2E-90 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CNX65_RS14365 ffe4b9a43d36d4363023d4919f44764d 527 Gene3D G3DSA:3.40.630.10 20 300 5.5E-53 T 28-03-2018 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 SUPERFAMILY SSF55347 204 511 1.41E-110 T 28-03-2018 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 24 512 87.266 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 216 511 1.1E-109 T 28-03-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 28 214 1.6E-62 T 28-03-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 SUPERFAMILY SSF51735 14 217 5.71E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 PIRSF PIRSF000110 5 513 4.0E-177 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 264 280 4.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 246 263 4.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 353 379 4.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 170 183 4.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 194 222 4.4E-49 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 Gene3D G3DSA:3.30.360.10 216 513 4.0E-123 T 28-03-2018 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 26 512 4.1E-200 T 28-03-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 204 210 - T 28-03-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 CNX65_RS25810 5a46176e358c6b7a1d32f8b6830f7c91 513 Gene3D G3DSA:3.40.50.720 22 215 6.8E-68 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 579 810 4.4E-57 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Pfam PF03710 Glutamate-ammonia ligase adenylyltransferase 88 307 7.1E-34 T 28-03-2018 IPR005190 Glutamate-ammonia ligase adenylyltransferase, repeated domain GO:0008882 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 SUPERFAMILY SSF81593 824 976 2.43E-36 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Pfam PF08335 GlnD PII-uridylyltransferase 328 474 2.4E-32 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Pfam PF08335 GlnD PII-uridylyltransferase 833 974 6.0E-21 T 28-03-2018 IPR013546 PII-uridylyltransferase/Glutamine-synthetase adenylyltransferase GO:0016779 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 SUPERFAMILY SSF81301 551 819 3.92E-66 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Gene3D G3DSA:3.30.460.10 169 314 3.8E-49 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Gene3D G3DSA:3.30.460.10 661 818 7.0E-53 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Gene3D G3DSA:1.20.120.330 317 478 2.3E-46 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Gene3D G3DSA:1.20.120.330 822 978 4.1E-46 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Hamap MF_00802 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme [glnE]. 83 966 16.606 T 28-03-2018 IPR023057 Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme GO:0008882 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 SUPERFAMILY SSF81301 70 314 5.89E-56 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 SUPERFAMILY SSF81593 320 475 6.91E-34 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Gene3D G3DSA:1.10.4050.10 60 160 1.0E-18 T 28-03-2018 CNX65_RS04510 43ab97ef17d88bdc1d67223e51329dd3 978 Gene3D G3DSA:1.10.4050.10 553 660 1.4E-17 T 28-03-2018 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Gene3D G3DSA:2.10.230.10 170 234 9.5E-16 T 28-03-2018 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Gene3D G3DSA:1.10.287.110 6 156 4.7E-28 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 SUPERFAMILY SSF49493 139 178 1.07E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 SUPERFAMILY SSF49493 239 287 1.07E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 10 375 1.8E-117 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 SMART SM00271 9 67 1.5E-25 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 PRINTS PR00625 DnaJ domain signature 12 30 1.2E-21 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 PRINTS PR00625 DnaJ domain signature 67 86 1.2E-21 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 PRINTS PR00625 DnaJ domain signature 47 67 1.2E-21 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 PRINTS PR00625 DnaJ domain signature 30 45 1.2E-21 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Gene3D G3DSA:2.60.260.20 235 280 1.0E-11 T 28-03-2018 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Gene3D G3DSA:2.60.260.20 281 388 5.3E-26 T 28-03-2018 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Pfam PF00226 DnaJ domain 10 72 1.4E-24 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 SUPERFAMILY SSF46565 9 108 7.98E-29 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 7 396 36.488 T 28-03-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 SUPERFAMILY SSF57938 160 235 3.14E-18 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Pfam PF00684 DnaJ central domain 173 233 2.8E-11 T 28-03-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 Pfam PF01556 DnaJ C terminal domain 146 358 1.6E-37 T 28-03-2018 IPR002939 Chaperone DnaJ, C-terminal CNX65_RS34325 d899649877e20f038d5feff5d41f205f 396 SUPERFAMILY SSF49493 285 369 1.1E-19 T 28-03-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 CNX65_RS28055 b1f0e709264823b9ca273465bcc4f323 393 SUPERFAMILY SSF53383 7 391 6.49E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS28055 b1f0e709264823b9ca273465bcc4f323 393 Gene3D G3DSA:3.90.1150.10 291 393 6.3E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS28055 b1f0e709264823b9ca273465bcc4f323 393 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 207 227 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CNX65_RS28055 b1f0e709264823b9ca273465bcc4f323 393 Hamap MF_02038 Probable hercynylcysteine sulfoxide lyase [egtE]. 9 392 35.183 T 28-03-2018 IPR027563 Pyridoxal-phosphate-dependent protein EgtE CNX65_RS28055 b1f0e709264823b9ca273465bcc4f323 393 Gene3D G3DSA:3.40.640.10 36 288 9.5E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS28055 b1f0e709264823b9ca273465bcc4f323 393 Pfam PF00266 Aminotransferase class-V 22 385 1.5E-57 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS33005 9f55836049e5d12fc0f02878e4582489 290 Pfam PF01040 UbiA prenyltransferase family 20 262 2.0E-30 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CNX65_RS33005 9f55836049e5d12fc0f02878e4582489 290 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 3 287 20.819 T 28-03-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CNX65_RS33005 9f55836049e5d12fc0f02878e4582489 290 PIRSF PIRSF005355 1 290 1.1E-81 T 28-03-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 CNX65_RS33005 9f55836049e5d12fc0f02878e4582489 290 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 12 285 6.4E-88 T 28-03-2018 CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 Gene3D G3DSA:3.40.50.880 1 227 1.6E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 262 304 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 SUPERFAMILY SSF52317 2 190 4.31E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 SUPERFAMILY SSF46689 209 259 6.45E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 SUPERFAMILY SSF46689 262 311 2.02E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 Pfam PF01965 DJ-1/PfpI family 2 168 1.7E-7 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 SMART SM00342 225 308 1.0E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 Gene3D G3DSA:1.10.10.60 263 315 1.2E-13 T 28-03-2018 CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 Gene3D G3DSA:1.10.10.60 228 262 2.3E-12 T 28-03-2018 CNX65_RS16985 35bf22757b482a28e51deaa9f73edb0c 329 Pfam PF12833 Helix-turn-helix domain 231 310 1.4E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 Pfam PF00326 Prolyl oligopeptidase family 427 634 7.0E-47 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 SUPERFAMILY SSF82171 15 358 2.24E-23 T 28-03-2018 CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 Pfam PF07676 WD40-like Beta Propeller Repeat 58 82 0.0018 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 Pfam PF07676 WD40-like Beta Propeller Repeat 183 209 0.073 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 Pfam PF07676 WD40-like Beta Propeller Repeat 96 128 8.1E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 Gene3D G3DSA:3.40.50.1820 370 634 1.9E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 Gene3D G3DSA:2.130.10.150 72 267 3.4E-24 T 28-03-2018 CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 Gene3D G3DSA:2.130.10.150 14 71 3.1E-5 T 28-03-2018 CNX65_RS27450 c1b1796f34c5d3e67ee41c19957de031 634 SUPERFAMILY SSF53474 384 634 1.52E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS11625 036482667b20b8b44d4f60810090637b 200 Gene3D G3DSA:3.40.50.360 1 180 7.4E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS11625 036482667b20b8b44d4f60810090637b 200 TIGRFAM TIGR04037 LLM_duo_CE1759: LLM-partnered FMN reductase, CE1759 family 4 196 1.6E-83 T 28-03-2018 IPR023932 Uncharacterised protein family, CE1759 CNX65_RS11625 036482667b20b8b44d4f60810090637b 200 Pfam PF03358 NADPH-dependent FMN reductase 2 154 5.9E-36 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CNX65_RS11625 036482667b20b8b44d4f60810090637b 200 SUPERFAMILY SSF52218 3 178 2.33E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 SUPERFAMILY SSF52440 5 134 2.97E-37 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 290 318 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 7 347 2.3E-105 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 6 348 40.434 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 Pfam PF07478 D-ala D-ala ligase C-terminus 143 345 6.1E-66 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 SUPERFAMILY SSF56059 135 348 1.08E-54 T 28-03-2018 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 Pfam PF01820 D-ala D-ala ligase N-terminus 7 124 9.3E-31 T 28-03-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 PIRSF PIRSF039102 3 353 1.4E-108 T 28-03-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 102 113 - T 28-03-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 Gene3D G3DSA:3.40.50.20 1 130 1.7E-46 T 28-03-2018 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 Gene3D G3DSA:3.30.1490.20 131 205 1.2E-17 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS29420 fb6447ba67deceb12d6c33e0d3eef310 355 Gene3D G3DSA:3.30.470.20 206 353 1.5E-38 T 28-03-2018 CNX65_RS23370 1b757064bd522468b38747d674053517 818 Gene3D G3DSA:1.10.10.10 1 97 5.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23370 1b757064bd522468b38747d674053517 818 SUPERFAMILY SSF55073 368 516 6.59E-13 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS23370 1b757064bd522468b38747d674053517 818 Gene3D G3DSA:3.30.70.1230 363 536 1.3E-9 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS23370 1b757064bd522468b38747d674053517 818 Pfam PF00486 Transcriptional regulatory protein, C terminal 23 94 1.6E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS23370 1b757064bd522468b38747d674053517 818 Gene3D G3DSA:1.25.40.10 98 279 2.8E-25 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS23370 1b757064bd522468b38747d674053517 818 Pfam PF13191 AAA ATPase domain 548 728 1.4E-10 T 28-03-2018 CNX65_RS23370 1b757064bd522468b38747d674053517 818 SMART SM00862 15 94 6.4E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS23370 1b757064bd522468b38747d674053517 818 SUPERFAMILY SSF46894 4 94 5.95E-10 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS23370 1b757064bd522468b38747d674053517 818 Gene3D G3DSA:3.40.50.300 537 738 1.6E-5 T 28-03-2018 CNX65_RS23370 1b757064bd522468b38747d674053517 818 SUPERFAMILY SSF52540 671 771 7.89E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23370 1b757064bd522468b38747d674053517 818 SUPERFAMILY SSF52540 540 615 7.89E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23370 1b757064bd522468b38747d674053517 818 SUPERFAMILY SSF48452 96 264 3.37E-39 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS23370 1b757064bd522468b38747d674053517 818 SMART SM01043 101 246 4.3E-47 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS23370 1b757064bd522468b38747d674053517 818 Pfam PF03704 Bacterial transcriptional activator domain 101 246 5.0E-44 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS18820 01e8939329f31fbbb41576f2067aed8d 189 Gene3D G3DSA:3.40.1410.10 11 175 1.3E-6 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS01375 485fb2f3561c5161326d1bc2f8896f93 234 Pfam PF07508 Recombinase 180 228 4.2E-5 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CNX65_RS01375 485fb2f3561c5161326d1bc2f8896f93 234 SUPERFAMILY SSF53041 1 155 9.16E-24 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS01375 485fb2f3561c5161326d1bc2f8896f93 234 SMART SM00857 3 156 1.5E-30 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS01375 485fb2f3561c5161326d1bc2f8896f93 234 Pfam PF00239 Resolvase, N terminal domain 4 156 7.0E-28 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS01375 485fb2f3561c5161326d1bc2f8896f93 234 Gene3D G3DSA:3.40.50.1390 1 164 4.3E-28 T 28-03-2018 CNX65_RS32140 539059c45bfd721cbbdbfb50d00df480 101 Gene3D G3DSA:3.40.30.10 4 101 1.2E-22 T 28-03-2018 CNX65_RS32140 539059c45bfd721cbbdbfb50d00df480 101 SUPERFAMILY SSF52833 2 101 1.78E-27 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS32140 539059c45bfd721cbbdbfb50d00df480 101 Pfam PF00085 Thioredoxin 2 98 4.2E-21 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CNX65_RS32140 539059c45bfd721cbbdbfb50d00df480 101 PIRSF PIRSF000077 1 101 1.7E-24 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CNX65_RS04955 39d2af9f982af6b406172081aef923c0 377 Pfam PF01636 Phosphotransferase enzyme family 169 316 4.6E-10 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS04955 39d2af9f982af6b406172081aef923c0 377 SUPERFAMILY SSF56112 115 363 1.46E-19 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS04955 39d2af9f982af6b406172081aef923c0 377 Gene3D G3DSA:1.10.510.10 172 369 2.8E-15 T 28-03-2018 CNX65_RS12890 adf4dab9ea6f4edb7658874f1ed6fc91 372 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 211 216 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS12890 adf4dab9ea6f4edb7658874f1ed6fc91 372 ProSitePatterns PS00135 Serine proteases, trypsin family, serine active site. 321 332 - T 28-03-2018 IPR033116 Serine proteases, trypsin family, serine active site CNX65_RS12890 adf4dab9ea6f4edb7658874f1ed6fc91 372 SUPERFAMILY SSF50494 186 344 2.21E-15 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS12890 adf4dab9ea6f4edb7658874f1ed6fc91 372 Gene3D G3DSA:2.40.10.10 182 265 4.0E-13 T 28-03-2018 CNX65_RS30590 a7110868cb1bb590086b511f5b4d81ac 551 PIRSF PIRSF036654 1 550 1.1E-273 T 28-03-2018 IPR014614 Uncharacterised conserved protein UCP036654 GO:0016627|GO:0055114 CNX65_RS30590 a7110868cb1bb590086b511f5b4d81ac 551 Pfam PF00890 FAD binding domain 6 532 1.4E-99 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS30590 a7110868cb1bb590086b511f5b4d81ac 551 Gene3D G3DSA:3.50.50.60 1 353 4.8E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30590 a7110868cb1bb590086b511f5b4d81ac 551 Gene3D G3DSA:3.50.50.60 364 548 7.0E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30590 a7110868cb1bb590086b511f5b4d81ac 551 SUPERFAMILY SSF51905 487 550 2.51E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30590 a7110868cb1bb590086b511f5b4d81ac 551 SUPERFAMILY SSF51905 2 284 2.51E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20165 5f969f8ddeebd96ff28d7c4a85174e1f 493 SMART SM00220 18 272 3.6E-56 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS20165 5f969f8ddeebd96ff28d7c4a85174e1f 493 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 47 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS20165 5f969f8ddeebd96ff28d7c4a85174e1f 493 Gene3D G3DSA:3.30.200.20 5 105 5.4E-20 T 28-03-2018 CNX65_RS20165 5f969f8ddeebd96ff28d7c4a85174e1f 493 SUPERFAMILY SSF56112 12 278 9.85E-67 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS20165 5f969f8ddeebd96ff28d7c4a85174e1f 493 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 141 153 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS20165 5f969f8ddeebd96ff28d7c4a85174e1f 493 Gene3D G3DSA:1.10.510.10 106 333 6.2E-46 T 28-03-2018 CNX65_RS20165 5f969f8ddeebd96ff28d7c4a85174e1f 493 Pfam PF00069 Protein kinase domain 19 269 4.9E-48 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS12830 f0eeda299bd598f158338ebc32d75f1f 404 Gene3D G3DSA:3.40.190.10 157 343 1.2E-12 T 28-03-2018 CNX65_RS12830 f0eeda299bd598f158338ebc32d75f1f 404 Gene3D G3DSA:3.40.190.10 45 156 4.7E-4 T 28-03-2018 CNX65_RS12830 f0eeda299bd598f158338ebc32d75f1f 404 SUPERFAMILY SSF53850 35 392 8.01E-28 T 28-03-2018 CNX65_RS12830 f0eeda299bd598f158338ebc32d75f1f 404 Pfam PF01547 Bacterial extracellular solute-binding protein 57 198 4.5E-4 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS16260 f53b7a01e28ec6353600648831a8a187 388 Gene3D G3DSA:3.40.640.10 18 243 4.7E-47 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS16260 f53b7a01e28ec6353600648831a8a187 388 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 18 380 6.7E-111 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS16260 f53b7a01e28ec6353600648831a8a187 388 SUPERFAMILY SSF53383 11 383 4.21E-95 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS16260 f53b7a01e28ec6353600648831a8a187 388 PIRSF PIRSF000390 7 388 6.5E-107 T 28-03-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase CNX65_RS16260 f53b7a01e28ec6353600648831a8a187 388 Gene3D G3DSA:3.90.1150.10 244 388 2.7E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS14625 c8cee6e3a519444e40d2e9523b7d8667 282 SUPERFAMILY SSF46955 3 104 9.52E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS14625 c8cee6e3a519444e40d2e9523b7d8667 282 Pfam PF13411 MerR HTH family regulatory protein 5 73 8.6E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS14625 c8cee6e3a519444e40d2e9523b7d8667 282 Gene3D G3DSA:1.10.1660.10 2 180 5.0E-19 T 28-03-2018 CNX65_RS14625 c8cee6e3a519444e40d2e9523b7d8667 282 SMART SM00422 4 74 2.8E-11 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS06720 35f8ddd3426f818c462b7d1a8acbe907 180 SUPERFAMILY SSF52540 5 173 9.56E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06720 35f8ddd3426f818c462b7d1a8acbe907 180 Gene3D G3DSA:3.40.50.300 4 174 5.6E-53 T 28-03-2018 CNX65_RS06720 35f8ddd3426f818c462b7d1a8acbe907 180 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 5 173 4.8E-52 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06720 35f8ddd3426f818c462b7d1a8acbe907 180 PIRSF PIRSF006135 3 176 4.4E-50 T 28-03-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00030+2.7.1.15|KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06360 4b9e528631422c074a9f4ce357b62c0d 169 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 51 3.7E-11 T 28-03-2018 IPR025161 Putative transposase IS4/IS5 family CNX65_RS16340 70b6f8f28bb0f95116593f1604f188fa 190 Pfam PF01872 RibD C-terminal domain 2 181 8.9E-13 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS16340 70b6f8f28bb0f95116593f1604f188fa 190 Gene3D G3DSA:3.40.430.10 2 187 5.7E-36 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS16340 70b6f8f28bb0f95116593f1604f188fa 190 SUPERFAMILY SSF53597 2 189 2.62E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 PRINTS PR00107 Phosphocarrier protein signature 40 55 3.8E-13 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 PRINTS PR00107 Phosphocarrier protein signature 13 29 3.8E-13 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 PRINTS PR00107 Phosphocarrier protein signature 55 72 3.8E-13 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 83 1.8E-25 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 Pfam PF00381 PTS HPr component phosphorylation site 3 84 3.0E-26 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 Gene3D G3DSA:3.30.1340.10 1 86 4.1E-29 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 13 20 - T 28-03-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site CNX65_RS26185 f3526e2c9d35462ef3f0a3eed1d77625 90 SUPERFAMILY SSF55594 1 89 6.02E-23 T 28-03-2018 IPR000032 Phosphocarrier protein HPr-like CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 Hamap MF_00580 10 kDa chaperonin [groS]. 4 97 25.784 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 ProSitePatterns PS00681 Chaperonins cpn10 signature. 5 29 - T 28-03-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 SUPERFAMILY SSF50129 3 97 1.32E-34 T 28-03-2018 IPR011032 GroES-like CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 PRINTS PR00297 10kDa chaperonin signature 5 20 5.9E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 PRINTS PR00297 10kDa chaperonin signature 62 74 5.9E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 PRINTS PR00297 10kDa chaperonin signature 83 96 5.9E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 PRINTS PR00297 10kDa chaperonin signature 27 48 5.9E-31 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 Pfam PF00166 Chaperonin 10 Kd subunit 4 96 3.2E-35 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 Gene3D G3DSA:2.30.33.40 1 97 1.5E-39 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS32110 214ad49f4724761e2c6a9333e2e1f58c 97 SMART SM00883 4 96 3.6E-54 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 10 96 2.9E-16 T 28-03-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 SMART SM00642 132 568 3.2E-8 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 SUPERFAMILY SSF51445 500 576 1.61E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 SUPERFAMILY SSF51445 133 471 1.61E-134 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 TIGRFAM TIGR02100 glgX_debranch: glycogen debranching enzyme GlgX 6 703 0.0 T 28-03-2018 IPR011837 Glycogen debranching enzyme, GlgX type GO:0004133|GO:0004553|GO:0005980 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 SUPERFAMILY SSF81296 5 147 1.34E-42 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 Pfam PF00128 Alpha amylase, catalytic domain 188 531 1.2E-14 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 Gene3D G3DSA:2.60.40.1180 592 708 2.6E-33 T 28-03-2018 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 Gene3D G3DSA:3.20.20.80 137 582 1.1E-112 T 28-03-2018 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 SUPERFAMILY SSF51011 590 703 5.4E-27 T 28-03-2018 CNX65_RS25415 1c4220a5a73b126a43a97f0b578b5f81 708 Gene3D G3DSA:2.60.40.10 5 136 1.5E-48 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS03685 5ea9890601508f27fd2c9f6d41eee3bf 344 Pfam PF13343 Bacterial extracellular solute-binding protein 80 313 1.1E-24 T 28-03-2018 CNX65_RS03685 5ea9890601508f27fd2c9f6d41eee3bf 344 Gene3D G3DSA:3.40.190.10 136 342 2.3E-30 T 28-03-2018 CNX65_RS03685 5ea9890601508f27fd2c9f6d41eee3bf 344 TIGRFAM TIGR01254 sfuA: ABC transporter periplasmic binding protein, thiB subfamily 31 338 3.4E-68 T 28-03-2018 IPR005948 Thiamine/thiamin pyrophosphate-binding periplasmic protein, ABC transporter GO:0015888|GO:0030288|GO:0030975 CNX65_RS03685 5ea9890601508f27fd2c9f6d41eee3bf 344 SUPERFAMILY SSF53850 33 339 1.27E-47 T 28-03-2018 CNX65_RS10345 c6c69b4401e7b930d1c3392fd694ce95 220 Gene3D G3DSA:3.40.50.620 21 159 6.0E-23 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS10345 c6c69b4401e7b930d1c3392fd694ce95 220 Pfam PF02698 DUF218 domain 42 145 9.2E-18 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CNX65_RS28185 0c9c7c4960d89d5cc71f16d9726af250 187 SUPERFAMILY SSF55729 1 183 1.68E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS28185 0c9c7c4960d89d5cc71f16d9726af250 187 Pfam PF13508 Acetyltransferase (GNAT) domain 64 163 6.2E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS28185 0c9c7c4960d89d5cc71f16d9726af250 187 Gene3D G3DSA:3.40.630.30 1 187 3.0E-24 T 28-03-2018 CNX65_RS23110 db2a4c3d3e2de0931d66f47337e0527c 315 Gene3D G3DSA:3.40.50.1100 27 133 6.0E-28 T 28-03-2018 CNX65_RS23110 db2a4c3d3e2de0931d66f47337e0527c 315 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 20 300 4.2E-62 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS23110 db2a4c3d3e2de0931d66f47337e0527c 315 Gene3D G3DSA:3.40.50.1100 134 308 2.9E-27 T 28-03-2018 CNX65_RS23110 db2a4c3d3e2de0931d66f47337e0527c 315 SUPERFAMILY SSF53686 5 303 1.7E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 SUPERFAMILY SSF51998 160 591 6.1E-130 T 28-03-2018 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 SUPERFAMILY SSF51998 625 699 6.1E-130 T 28-03-2018 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 Pfam PF02867 Ribonucleotide reductase, barrel domain 160 695 4.9E-141 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 Pfam PF08471 Class II vitamin B12-dependent ribonucleotide reductase 56 139 1.1E-19 T 28-03-2018 IPR013678 Ribonucleotide reductase class II vitamin B12-dependent, N-terminal domain GO:0004748|GO:0050897|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 Gene3D G3DSA:3.20.70.20 51 702 4.9E-167 T 28-03-2018 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 541 568 5.1E-11 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 235 254 5.1E-11 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 362 373 5.1E-11 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 PRINTS PR01183 Ribonucleotide reductase large chain signature 434 456 5.1E-11 T 28-03-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS07090 0c7687b406ae41a196bde79d2d6181f1 948 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 81 705 2.3E-182 T 28-03-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 CNX65_RS30935 550243a5850e12ca31ab4e5f040ae889 138 Gene3D G3DSA:1.20.120.400 20 136 1.1E-42 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CNX65_RS30935 550243a5850e12ca31ab4e5f040ae889 138 SUPERFAMILY SSF109770 20 137 2.62E-52 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CNX65_RS30935 550243a5850e12ca31ab4e5f040ae889 138 TIGRFAM TIGR02753 sodN: superoxide dismutase, Ni 12 137 1.7E-48 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CNX65_RS30935 550243a5850e12ca31ab4e5f040ae889 138 Pfam PF09055 Nickel-containing superoxide dismutase 16 136 2.6E-45 T 28-03-2018 IPR014123 Superoxide dismutase, Nickel-type GO:0004784|GO:0016151|GO:0016209 MetaCyc: PWY-6854 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 SUPERFAMILY SSF47781 65 135 1.74E-18 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 SUPERFAMILY SSF46929 148 196 5.76E-9 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 191 1.6E-37 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 SMART SM00278 72 91 210.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 SMART SM00278 107 126 2.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Gene3D G3DSA:2.40.50.140 1 62 4.3E-21 T 28-03-2018 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Gene3D G3DSA:1.10.8.10 162 198 2.1E-15 T 28-03-2018 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Pfam PF07499 RuvA, C-terminal domain 149 194 3.5E-12 T 28-03-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Gene3D G3DSA:1.10.150.20 66 123 1.2E-16 T 28-03-2018 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Gene3D G3DSA:1.10.150.20 124 161 0.015 T 28-03-2018 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Pfam PF14520 Helix-hairpin-helix domain 71 129 6.1E-14 T 28-03-2018 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 195 27.912 T 28-03-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 Pfam PF01330 RuvA N terminal domain 2 61 1.1E-16 T 28-03-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 CNX65_RS08435 668defc0c37624ca6c4e3033c86fd845 198 SUPERFAMILY SSF50249 2 62 2.17E-13 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS08095 b92acbb003c9708bfcc16e275bd23b00 330 Gene3D G3DSA:3.20.20.100 9 325 1.3E-61 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS08095 b92acbb003c9708bfcc16e275bd23b00 330 Pfam PF00248 Aldo/keto reductase family 19 323 4.7E-45 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS08095 b92acbb003c9708bfcc16e275bd23b00 330 SUPERFAMILY SSF51430 17 323 1.96E-62 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS19180 547ef13ac51b4187ef28bcd2df5db48b 275 Pfam PF01261 Xylose isomerase-like TIM barrel 25 220 1.4E-27 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS19180 547ef13ac51b4187ef28bcd2df5db48b 275 Gene3D G3DSA:3.20.20.150 3 275 2.9E-44 T 28-03-2018 CNX65_RS19180 547ef13ac51b4187ef28bcd2df5db48b 275 SUPERFAMILY SSF51658 16 249 6.77E-41 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 Pfam PF13193 AMP-binding enzyme C-terminal domain 440 516 3.4E-11 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 Gene3D G3DSA:3.30.300.30 425 528 2.8E-29 T 28-03-2018 CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 Gene3D G3DSA:2.30.38.10 338 422 8.8E-20 T 28-03-2018 CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 Pfam PF00501 AMP-binding enzyme 24 432 1.6E-81 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 SUPERFAMILY SSF56801 13 525 2.09E-126 T 28-03-2018 CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 Gene3D G3DSA:3.40.50.980 174 330 2.0E-31 T 28-03-2018 CNX65_RS13610 652d350eae9a101e6f162eda04d446a2 529 Gene3D G3DSA:3.40.50.980 12 173 6.8E-37 T 28-03-2018 CNX65_RS28265 b8ac6c2981700e7e2399b7f0e30c086d 362 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 15 349 5.0E-90 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS28265 b8ac6c2981700e7e2399b7f0e30c086d 362 ProSitePatterns PS01348 MraY family signature 2. 182 193 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS28265 b8ac6c2981700e7e2399b7f0e30c086d 362 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 46 58 7.3E-6 T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS28265 b8ac6c2981700e7e2399b7f0e30c086d 362 Pfam PF00953 Glycosyl transferase family 4 89 279 3.7E-36 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CNX65_RS28265 b8ac6c2981700e7e2399b7f0e30c086d 362 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 3 353 22.889 T 28-03-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS28265 b8ac6c2981700e7e2399b7f0e30c086d 362 ProSitePatterns PS01347 MraY family signature 1. 46 58 - T 28-03-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 Gene3D G3DSA:1.10.1740.10 21 99 5.1E-18 T 28-03-2018 CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 SUPERFAMILY SSF88659 121 185 1.64E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 Pfam PF04545 Sigma-70, region 4 133 182 3.0E-11 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 ProSitePatterns PS01063 Sigma-70 factors ECF subfamily signature. 56 88 - T 28-03-2018 IPR000838 RNA polymerase sigma factor 70, ECF, conserved site GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 29 184 9.0E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 SUPERFAMILY SSF88946 26 116 1.18E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 Gene3D G3DSA:1.10.10.10 100 187 1.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24780 90256a5f37dfb781298804af7a7ef967 188 Pfam PF04542 Sigma-70 region 2 33 101 1.2E-16 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS17595 a9ccd62072f630bcecae917f42284d19 319 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 317 4.1E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17595 a9ccd62072f630bcecae917f42284d19 319 Gene3D G3DSA:1.10.3720.10 2 306 2.7E-34 T 28-03-2018 CNX65_RS17595 a9ccd62072f630bcecae917f42284d19 319 SUPERFAMILY SSF161098 93 305 2.13E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09960 2f4c2d33c6f1a4dc7382b56f11bb3c59 324 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 22 78 2.0E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS09960 2f4c2d33c6f1a4dc7382b56f11bb3c59 324 Gene3D G3DSA:3.90.180.10 4 155 9.0E-17 T 28-03-2018 CNX65_RS09960 2f4c2d33c6f1a4dc7382b56f11bb3c59 324 SUPERFAMILY SSF51735 117 284 4.11E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09960 2f4c2d33c6f1a4dc7382b56f11bb3c59 324 Gene3D G3DSA:3.90.180.10 261 324 0.15 T 28-03-2018 CNX65_RS09960 2f4c2d33c6f1a4dc7382b56f11bb3c59 324 SUPERFAMILY SSF50129 19 149 3.04E-16 T 28-03-2018 IPR011032 GroES-like CNX65_RS09960 2f4c2d33c6f1a4dc7382b56f11bb3c59 324 Gene3D G3DSA:3.40.50.720 156 221 4.5E-5 T 28-03-2018 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 Hamap MF_01976 Pyrophosphate--fructose 6-phosphate 1-phosphotransferase [pfp]. 1 341 44.144 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 Pfam PF00365 Phosphofructokinase 2 296 1.4E-103 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 TIGRFAM TIGR02483 PFK_mixed: phosphofructokinase 2 321 6.9E-151 T 28-03-2018 IPR012829 Phosphofructokinase, mixed-substrate PFK group III GO:0006096|GO:0047334 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 Gene3D G3DSA:3.40.50.450 1 199 1.9E-78 T 28-03-2018 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 SUPERFAMILY SSF53784 1 333 5.89E-122 T 28-03-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 ProSitePatterns PS00433 Phosphofructokinase signature. 265 283 - T 28-03-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 Gene3D G3DSA:3.40.50.450 200 322 1.7E-15 T 28-03-2018 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PIRSF PIRSF000532 1 339 8.8E-122 T 28-03-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 5 24 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 211 223 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS06900 3891880a0ef0c18ab3cd26e6cfbba4ab 341 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 261 283 8.6E-73 T 28-03-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 CNX65_RS14415 777c917e0e7b0c32a68e4b8b0b6f9958 326 Gene3D G3DSA:1.10.10.10 2 69 9.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14415 777c917e0e7b0c32a68e4b8b0b6f9958 326 Pfam PF08279 HTH domain 11 65 1.1E-13 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CNX65_RS14415 777c917e0e7b0c32a68e4b8b0b6f9958 326 Pfam PF13280 WYL domain 147 311 4.0E-23 T 28-03-2018 IPR026881 WYL domain CNX65_RS14415 777c917e0e7b0c32a68e4b8b0b6f9958 326 SUPERFAMILY SSF46785 8 71 1.04E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 Gene3D G3DSA:3.40.50.1100 138 306 1.0E-33 T 28-03-2018 CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 SUPERFAMILY SSF53686 3 306 1.05E-64 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 Gene3D G3DSA:3.40.50.1100 39 137 1.3E-20 T 28-03-2018 CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 Gene3D G3DSA:3.30.470.20 538 747 2.3E-32 T 28-03-2018 CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 Pfam PF13535 ATP-grasp domain 490 637 4.9E-20 T 28-03-2018 CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 6 290 4.3E-44 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 Gene3D G3DSA:3.30.1490.20 487 537 5.8E-12 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 Gene3D G3DSA:3.40.50.720 325 486 0.032 T 28-03-2018 CNX65_RS22400 0190645fc5bc44f87f063c194d55e156 756 SUPERFAMILY SSF56059 444 689 1.04E-39 T 28-03-2018 CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 Pfam PF00270 DEAD/DEAH box helicase 21 206 8.0E-26 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 SMART SM00490 289 417 2.0E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 Gene3D G3DSA:1.10.10.10 1028 1080 0.1 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 Pfam PF00271 Helicase conserved C-terminal domain 352 417 3.6E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 Gene3D G3DSA:3.40.50.300 259 430 1.5E-27 T 28-03-2018 CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 Pfam PF08494 DEAD/H associated 680 873 9.8E-78 T 28-03-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 SMART SM00382 33 404 2.6E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 Gene3D G3DSA:3.40.50.300 5 238 1.4E-35 T 28-03-2018 CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 Gene3D G3DSA:1.10.10.10 440 1005 0.012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 SMART SM00487 16 233 1.5E-37 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 SUPERFAMILY SSF52540 253 301 2.11E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 SUPERFAMILY SSF52540 29 206 2.11E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07000 7095af577c936c827a7e4d080ee2837b 1595 SUPERFAMILY SSF52540 348 422 2.11E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03795 417548f25162662cd864f0a7650c3c3f 292 SUPERFAMILY SSF55729 202 289 4.8E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS03795 417548f25162662cd864f0a7650c3c3f 292 Gene3D G3DSA:3.40.630.30 13 292 9.0E-20 T 28-03-2018 CNX65_RS03795 417548f25162662cd864f0a7650c3c3f 292 Pfam PF00583 Acetyltransferase (GNAT) family 216 278 4.3E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS12795 646133f45c902cb1f7f92ac65f6551af 318 Gene3D G3DSA:2.60.130.10 44 286 4.0E-40 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS12795 646133f45c902cb1f7f92ac65f6551af 318 Pfam PF00775 Dioxygenase 114 188 1.2E-7 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CNX65_RS12795 646133f45c902cb1f7f92ac65f6551af 318 SUPERFAMILY SSF49482 60 258 5.36E-39 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS28595 0c6b7c9e4df8ee3419045060844909bb 438 TIGRFAM TIGR00797 matE: MATE efflux family protein 21 408 1.5E-88 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS28595 0c6b7c9e4df8ee3419045060844909bb 438 Pfam PF01554 MatE 21 181 1.2E-25 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS28595 0c6b7c9e4df8ee3419045060844909bb 438 Pfam PF01554 MatE 238 386 8.7E-14 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS28595 0c6b7c9e4df8ee3419045060844909bb 438 PIRSF PIRSF006603 9 437 1.7E-49 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 SUPERFAMILY SSF53850 90 287 1.77E-30 T 28-03-2018 CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 Gene3D G3DSA:3.40.190.10 89 177 3.0E-21 T 28-03-2018 CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 Pfam PF03466 LysR substrate binding domain 88 286 5.3E-35 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 SUPERFAMILY SSF46785 1 109 3.33E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 2.3E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 Gene3D G3DSA:3.40.190.10 178 263 8.9E-17 T 28-03-2018 CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 Gene3D G3DSA:1.10.10.10 1 86 1.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 4.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 4.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS23105 18f6290d6fc80959e750e3949c0ad37b 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 4.7E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 295 309 1.9E-7 T 28-03-2018 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 194 219 1.9E-7 T 28-03-2018 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.9E-7 T 28-03-2018 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 Gene3D G3DSA:3.50.50.60 2 208 1.1E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 Gene3D G3DSA:3.50.50.60 209 399 9.3E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 SUPERFAMILY SSF51905 6 46 1.78E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 SUPERFAMILY SSF51905 74 389 1.78E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 309 5.7E-14 T 28-03-2018 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.7E-8 T 28-03-2018 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 310 2.7E-8 T 28-03-2018 CNX65_RS19450 6317c9389bd828dcf98d4811fd5dc245 440 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 194 212 2.7E-8 T 28-03-2018 CNX65_RS30945 a7b8d9af9b3e37e73bdf4abba66bed89 202 PIRSF PIRSF000709 2 107 7.6E-10 T 28-03-2018 CNX65_RS30945 a7b8d9af9b3e37e73bdf4abba66bed89 202 PIRSF PIRSF000709 139 165 690.0 T 28-03-2018 CNX65_RS30945 a7b8d9af9b3e37e73bdf4abba66bed89 202 SMART SM00855 6 155 2.1E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS30945 a7b8d9af9b3e37e73bdf4abba66bed89 202 Gene3D G3DSA:3.40.50.1240 3 196 1.5E-46 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS30945 a7b8d9af9b3e37e73bdf4abba66bed89 202 SUPERFAMILY SSF53254 5 194 1.33E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS30945 a7b8d9af9b3e37e73bdf4abba66bed89 202 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 7 194 8.5E-48 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS24390 09f8ad085e923485b575141339e58570 529 SUPERFAMILY SSF51905 43 356 2.25E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24390 09f8ad085e923485b575141339e58570 529 SUPERFAMILY SSF51905 455 499 2.25E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24390 09f8ad085e923485b575141339e58570 529 Gene3D G3DSA:3.50.50.60 38 508 1.7E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24390 09f8ad085e923485b575141339e58570 529 Pfam PF01593 Flavin containing amine oxidoreductase 53 496 4.8E-32 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS21840 37ded25b73f697f0c85293687e7e0635 246 SUPERFAMILY SSF53335 28 229 2.09E-24 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS21840 37ded25b73f697f0c85293687e7e0635 246 Gene3D G3DSA:3.40.50.150 22 103 4.5E-10 T 28-03-2018 CNX65_RS21840 37ded25b73f697f0c85293687e7e0635 246 Gene3D G3DSA:3.40.50.150 104 157 0.029 T 28-03-2018 CNX65_RS21840 37ded25b73f697f0c85293687e7e0635 246 Pfam PF13649 Methyltransferase domain 53 143 4.9E-10 T 28-03-2018 CNX65_RS21840 37ded25b73f697f0c85293687e7e0635 246 Gene3D G3DSA:2.20.130.10 158 211 5.3E-20 T 28-03-2018 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 Pfam PF00067 Cytochrome P450 312 388 2.4E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 Pfam PF00067 Cytochrome P450 229 281 9.3E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 Gene3D G3DSA:1.10.630.10 40 421 1.7E-54 T 28-03-2018 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 360 369 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 PRINTS PR00359 B-class P450 signature 216 238 1.5E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 PRINTS PR00359 B-class P450 signature 161 177 1.5E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 PRINTS PR00359 B-class P450 signature 358 367 1.5E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 PRINTS PR00359 B-class P450 signature 115 126 1.5E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 PRINTS PR00359 B-class P450 signature 367 378 1.5E-20 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS15540 8bcacba291839d4f2ea33213ea462e31 422 SUPERFAMILY SSF48264 28 420 6.94E-72 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 400 1.2E-128 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 ProSitePatterns PS00737 Thiolases signature 2. 348 364 - T 28-03-2018 IPR020613 Thiolase, conserved site GO:0008152|GO:0016747 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 SUPERFAMILY SSF53901 280 401 3.03E-43 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 Pfam PF00108 Thiolase, N-terminal domain 5 270 2.2E-43 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 87 105 - T 28-03-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0008152|GO:0016747 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 ProSitePatterns PS00099 Thiolases active site. 383 396 - T 28-03-2018 IPR020610 Thiolase, active site GO:0008152|GO:0016747 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 Gene3D G3DSA:3.40.47.10 278 402 6.3E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 SUPERFAMILY SSF53901 2 276 3.36E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 Gene3D G3DSA:3.40.47.10 1 277 2.5E-48 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 PIRSF PIRSF000429 2 402 1.9E-110 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS21870 a224b47792b77d067fef65a8f7789642 402 Pfam PF02803 Thiolase, C-terminal domain 280 401 1.1E-45 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CNX65_RS02425 5a921f9b870934ab31a27848264b201a 332 Gene3D G3DSA:3.30.360.10 136 324 7.3E-40 T 28-03-2018 CNX65_RS02425 5a921f9b870934ab31a27848264b201a 332 SUPERFAMILY SSF55347 129 287 4.41E-37 T 28-03-2018 CNX65_RS02425 5a921f9b870934ab31a27848264b201a 332 SUPERFAMILY SSF51735 4 157 4.57E-54 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02425 5a921f9b870934ab31a27848264b201a 332 Gene3D G3DSA:3.40.50.720 2 135 1.8E-43 T 28-03-2018 CNX65_RS02425 5a921f9b870934ab31a27848264b201a 332 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 121 6.2E-25 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS23465 bf8cfc3e11c82e50aad17d1561e52f00 434 Gene3D G3DSA:3.40.50.1820 31 433 9.9E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23465 bf8cfc3e11c82e50aad17d1561e52f00 434 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 87 98 2.3E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS23465 bf8cfc3e11c82e50aad17d1561e52f00 434 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 57 65 2.3E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS23465 bf8cfc3e11c82e50aad17d1561e52f00 434 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 146 160 2.3E-8 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS23465 bf8cfc3e11c82e50aad17d1561e52f00 434 SUPERFAMILY SSF53474 327 411 3.27E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23465 bf8cfc3e11c82e50aad17d1561e52f00 434 SUPERFAMILY SSF53474 37 176 3.27E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23465 bf8cfc3e11c82e50aad17d1561e52f00 434 Pfam PF00561 alpha/beta hydrolase fold 56 209 6.7E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 SUPERFAMILY SSF47413 1 59 2.06E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 Gene3D G3DSA:1.10.10.60 2 14 0.0052 T 28-03-2018 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 Gene3D G3DSA:1.10.260.40 15 51 1.3E-22 T 28-03-2018 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 Gene3D G3DSA:3.40.50.2300 52 173 1.1E-22 T 28-03-2018 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 SMART SM00354 1 71 1.3E-27 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 Gene3D G3DSA:3.40.50.2300 174 307 1.7E-19 T 28-03-2018 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 9.8E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 Pfam PF13377 Periplasmic binding protein-like domain 168 322 5.1E-19 T 28-03-2018 CNX65_RS15045 cd90200291ed8d1be4810449ffdb2b1e 328 SUPERFAMILY SSF53822 58 305 9.66E-30 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 16 99 5.6E-25 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 Pfam PF00120 Glutamine synthetase, catalytic domain 107 441 1.5E-127 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 SMART SM01230 106 357 5.3E-127 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 Gene3D G3DSA:3.30.590.10 106 447 1.4E-117 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 28-03-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 SUPERFAMILY SSF55931 108 444 2.65E-117 T 28-03-2018 CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 SUPERFAMILY SSF54368 8 104 5.36E-28 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS04455 858b7a7de1070c93c53bb77b671de559 447 Gene3D G3DSA:3.10.20.70 1 105 3.9E-31 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS16895 5b7e69eb29038dfa1281991b475a3e9a 330 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 22 329 4.4E-31 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CNX65_RS16895 5b7e69eb29038dfa1281991b475a3e9a 330 Gene3D G3DSA:3.40.50.720 18 127 2.3E-34 T 28-03-2018 CNX65_RS16895 5b7e69eb29038dfa1281991b475a3e9a 330 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 122 298 6.3E-51 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CNX65_RS16895 5b7e69eb29038dfa1281991b475a3e9a 330 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 239 255 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CNX65_RS16895 5b7e69eb29038dfa1281991b475a3e9a 330 Gene3D G3DSA:3.40.50.720 128 301 6.0E-48 T 28-03-2018 CNX65_RS16895 5b7e69eb29038dfa1281991b475a3e9a 330 SUPERFAMILY SSF52283 19 148 1.87E-36 T 28-03-2018 CNX65_RS16895 5b7e69eb29038dfa1281991b475a3e9a 330 SUPERFAMILY SSF51735 116 298 2.82E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 Hamap MF_02112 Proteasome-associated ATPase [mpa]. 58 578 50.58 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 SUPERFAMILY SSF52540 487 545 2.87E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 SUPERFAMILY SSF52540 237 446 2.87E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 Gene3D G3DSA:1.20.5.340 20 149 1.1E-7 T 28-03-2018 CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 Gene3D G3DSA:3.40.50.300 219 444 1.7E-54 T 28-03-2018 CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 Pfam PF16450 Proteasomal ATPase OB/ID domain 100 236 6.4E-54 T 28-03-2018 IPR032501 Proteasomal ATPase, OB/ID domain CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 279 429 5.9E-48 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 TIGRFAM TIGR03689 pup_AAA: proteasome ATPase 56 577 1.9E-254 T 28-03-2018 IPR022482 Proteasome ATPase GO:0000502|GO:0010498|GO:0016887|GO:0019941 CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 SMART SM00382 275 431 4.2E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS11350 763461bc5337b9237bf5c2251ca87180 599 ProSitePatterns PS00674 AAA-protein family signature. 399 417 - T 28-03-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 CNX65_RS05065 772f5eaaa9e504a3084e0152646693ba 90 Gene3D G3DSA:3.10.20.30 1 90 6.0E-23 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS05065 772f5eaaa9e504a3084e0152646693ba 90 SUPERFAMILY SSF54285 1 90 2.62E-25 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CNX65_RS05065 772f5eaaa9e504a3084e0152646693ba 90 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 10 90 1.8E-14 T 28-03-2018 IPR010038 MoaD, archaeal-type CNX65_RS05065 772f5eaaa9e504a3084e0152646693ba 90 Pfam PF02597 ThiS family 5 90 8.0E-20 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CNX65_RS07210 f5b153212296e6e177588924be4bfaeb 219 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 9 200 2.8E-28 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS07210 f5b153212296e6e177588924be4bfaeb 219 SUPERFAMILY SSF109854 3 139 1.34E-29 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS07210 f5b153212296e6e177588924be4bfaeb 219 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 137 3.8E-17 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS07210 f5b153212296e6e177588924be4bfaeb 219 Gene3D G3DSA:1.20.120.450 2 141 7.8E-18 T 28-03-2018 CNX65_RS07210 f5b153212296e6e177588924be4bfaeb 219 SUPERFAMILY SSF55718 144 218 1.41E-12 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 SUPERFAMILY SSF51735 160 304 6.55E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 4 418 9.0E-119 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 415 25.36 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 97 120 - T 28-03-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 SUPERFAMILY SSF69742 1 156 3.27E-44 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 SUPERFAMILY SSF69075 316 418 8.37E-17 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 Gene3D G3DSA:3.40.50.720 159 313 1.1E-23 T 28-03-2018 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 319 417 5.0E-21 T 28-03-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 Gene3D G3DSA:1.10.1200.70 330 418 1.7E-21 T 28-03-2018 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 304 7.8E-25 T 28-03-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 PIRSF PIRSF000445 1 431 1.5E-131 T 28-03-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS33165 1cc5a9a3f4229e068293ab39a82d26b0 438 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 154 8.3E-42 T 28-03-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 CNX65_RS06475 951fbe7112f72e9666687ca5c78f6349 748 Pfam PF13245 AAA domain 192 566 2.3E-12 T 28-03-2018 CNX65_RS06475 951fbe7112f72e9666687ca5c78f6349 748 Gene3D G3DSA:3.40.50.300 591 747 3.8E-15 T 28-03-2018 CNX65_RS06475 951fbe7112f72e9666687ca5c78f6349 748 Gene3D G3DSA:3.40.50.300 186 567 5.3E-33 T 28-03-2018 CNX65_RS06475 951fbe7112f72e9666687ca5c78f6349 748 SUPERFAMILY SSF52540 346 407 4.22E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06475 951fbe7112f72e9666687ca5c78f6349 748 SUPERFAMILY SSF52540 180 259 4.22E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06475 951fbe7112f72e9666687ca5c78f6349 748 SUPERFAMILY SSF52540 491 737 4.22E-48 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 Pfam PF04715 Anthranilate synthase component I, N terminal region 40 181 9.4E-32 T 28-03-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 Gene3D G3DSA:3.60.120.10 29 502 1.9E-167 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 SUPERFAMILY SSF56322 29 499 1.7E-155 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 Pfam PF00425 chorismate binding enzyme 237 490 2.0E-99 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 PRINTS PR00095 Anthranilate synthase component I signature 352 365 2.1E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 PRINTS PR00095 Anthranilate synthase component I signature 447 461 2.1E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 PRINTS PR00095 Anthranilate synthase component I signature 432 446 2.1E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 PRINTS PR00095 Anthranilate synthase component I signature 338 351 2.1E-24 T 28-03-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS27960 bf8a67f478e2c5a984842d6972de7c4a 513 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 39 498 1.7E-170 T 28-03-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 Gene3D G3DSA:2.40.30.10 2 96 4.5E-14 T 28-03-2018 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 SUPERFAMILY SSF52343 101 234 1.83E-29 T 28-03-2018 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 SUPERFAMILY SSF54292 223 338 1.7E-24 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 Gene3D G3DSA:3.40.50.80 97 229 9.1E-26 T 28-03-2018 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 Pfam PF00175 Oxidoreductase NAD-binding domain 107 215 5.9E-14 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 SUPERFAMILY SSF63380 2 95 1.38E-16 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 Pfam PF00970 Oxidoreductase FAD-binding domain 7 97 3.9E-7 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 Gene3D G3DSA:3.10.20.30 230 341 5.3E-24 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 258 330 1.3E-12 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS32955 40bda2f84c4c2e147a7894f257dd01ff 341 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 288 296 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CNX65_RS05655 7edae29a112566aac28f1a262142313e 325 Pfam PF00924 Mechanosensitive ion channel 97 296 2.8E-37 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CNX65_RS05655 7edae29a112566aac28f1a262142313e 325 Gene3D G3DSA:2.30.30.60 155 203 7.1E-9 T 28-03-2018 CNX65_RS05655 7edae29a112566aac28f1a262142313e 325 SUPERFAMILY SSF82689 204 297 8.24E-10 T 28-03-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 CNX65_RS05655 7edae29a112566aac28f1a262142313e 325 Gene3D G3DSA:3.30.70.100 204 299 3.0E-12 T 28-03-2018 CNX65_RS05655 7edae29a112566aac28f1a262142313e 325 SUPERFAMILY SSF50182 139 197 6.54E-12 T 28-03-2018 IPR010920 LSM domain CNX65_RS05655 7edae29a112566aac28f1a262142313e 325 SUPERFAMILY SSF82861 83 138 2.62E-10 T 28-03-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 Pfam PF00652 Ricin-type beta-trefoil lectin domain 370 495 4.5E-15 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 Pfam PF13620 Carboxypeptidase regulatory-like domain 180 238 1.7E-9 T 28-03-2018 CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 Gene3D G3DSA:2.60.40.1120 244 362 1.6E-4 T 28-03-2018 CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 SUPERFAMILY SSF50370 371 497 7.8E-23 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 SUPERFAMILY SSF117074 155 229 1.24E-11 T 28-03-2018 CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 Gene3D G3DSA:2.80.10.50 363 413 1.0E-7 T 28-03-2018 CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 Gene3D G3DSA:2.80.10.50 414 498 2.2E-16 T 28-03-2018 CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 SUPERFAMILY SSF117074 245 316 3.53E-6 T 28-03-2018 CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 SMART SM00458 362 498 3.4E-16 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS16040 cda17e5881d35e43677544546af162b0 498 Gene3D G3DSA:2.60.40.10 156 243 1.7E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS30970 e36cd43f397b78af20341497b83b6c9b 314 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 117 4.8E-25 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CNX65_RS30970 e36cd43f397b78af20341497b83b6c9b 314 Gene3D G3DSA:3.40.50.10330 1 134 1.5E-28 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CNX65_RS30970 e36cd43f397b78af20341497b83b6c9b 314 SUPERFAMILY SSF111331 2 314 2.09E-56 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CNX65_RS30970 e36cd43f397b78af20341497b83b6c9b 314 SMART SM00046 2 131 2.2E-12 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CNX65_RS22870 d25e6d4e9716c387feb24cb85370a353 330 Pfam PF00303 Thymidylate synthase 102 236 5.6E-10 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CNX65_RS22870 d25e6d4e9716c387feb24cb85370a353 330 Gene3D G3DSA:3.30.572.10 3 246 3.7E-27 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CNX65_RS22870 d25e6d4e9716c387feb24cb85370a353 330 SUPERFAMILY SSF55831 10 236 5.23E-30 T 28-03-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 CNX65_RS32915 d6ddc58fc5f8ae7fd15aa69bc39d8970 489 Gene3D G3DSA:1.10.645.10 84 271 1.1E-47 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32915 d6ddc58fc5f8ae7fd15aa69bc39d8970 489 TIGRFAM TIGR01962 NuoD: NADH dehydrogenase (quinone), D subunit 88 489 5.0E-166 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32915 d6ddc58fc5f8ae7fd15aa69bc39d8970 489 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 80 489 47.217 T 28-03-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32915 d6ddc58fc5f8ae7fd15aa69bc39d8970 489 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 125 136 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32915 d6ddc58fc5f8ae7fd15aa69bc39d8970 489 Gene3D G3DSA:1.10.645.10 272 485 1.3E-39 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32915 d6ddc58fc5f8ae7fd15aa69bc39d8970 489 SUPERFAMILY SSF56762 98 489 6.41E-121 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32915 d6ddc58fc5f8ae7fd15aa69bc39d8970 489 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 203 489 1.4E-107 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 Gene3D G3DSA:1.10.10.10 123 223 6.7E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 SMART SM00862 145 220 2.6E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 Gene3D G3DSA:3.40.50.2300 1 122 1.4E-31 T 28-03-2018 CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 Pfam PF00072 Response regulator receiver domain 3 112 1.1E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 SMART SM00448 1 112 6.8E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 6.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 SUPERFAMILY SSF52172 1 118 1.18E-37 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS27235 928b508dae1f6c64b1766b76a545e151 223 SUPERFAMILY SSF46894 123 221 6.52E-27 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SMART SM01043 108 252 1.9E-44 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Pfam PF00486 Transcriptional regulatory protein, C terminal 35 101 1.8E-9 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Gene3D G3DSA:3.40.50.300 280 434 1.1E-15 T 28-03-2018 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Pfam PF13424 Tetratricopeptide repeat 819 890 1.0E-12 T 28-03-2018 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SUPERFAMILY SSF48452 724 929 2.73E-21 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SUPERFAMILY SSF48452 104 267 1.52E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 PRINTS PR00364 Disease resistance protein signature 395 409 7.9E-10 T 28-03-2018 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 PRINTS PR00364 Disease resistance protein signature 317 332 7.9E-10 T 28-03-2018 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 PRINTS PR00364 Disease resistance protein signature 480 494 7.9E-10 T 28-03-2018 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Pfam PF03704 Bacterial transcriptional activator domain 108 251 4.0E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SMART SM00028 859 892 36.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SMART SM00028 899 932 3.8 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SMART SM00028 819 852 26.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Gene3D G3DSA:1.25.40.10 467 881 1.3E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Pfam PF13374 Tetratricopeptide repeat 902 932 0.0014 T 28-03-2018 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SUPERFAMILY SSF46894 13 101 2.3E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Gene3D G3DSA:1.10.10.10 2 104 5.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Gene3D G3DSA:1.25.40.10 105 279 5.9E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SMART SM00862 25 101 3.1E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Pfam PF00931 NB-ARC domain 314 545 4.2E-17 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 SUPERFAMILY SSF52540 284 546 3.19E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18075 2ff2e4e255d7c4fb134e1b4aec8bfac3 954 Gene3D G3DSA:3.30.70.100 882 947 8.8E-8 T 28-03-2018 CNX65_RS28500 4b920fa42958b2932b1c9da2dfc4bae6 291 Gene3D G3DSA:3.40.50.1820 5 286 4.7E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS28500 4b920fa42958b2932b1c9da2dfc4bae6 291 SUPERFAMILY SSF53474 12 281 2.17E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23960 5bc20ce965504454aa5f406eb0d030dd 300 SUPERFAMILY SSF53850 89 292 3.36E-34 T 28-03-2018 CNX65_RS23960 5bc20ce965504454aa5f406eb0d030dd 300 Gene3D G3DSA:3.40.190.10 87 182 4.2E-17 T 28-03-2018 CNX65_RS23960 5bc20ce965504454aa5f406eb0d030dd 300 SUPERFAMILY SSF46785 2 110 2.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23960 5bc20ce965504454aa5f406eb0d030dd 300 Pfam PF03466 LysR substrate binding domain 88 290 2.0E-37 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS23960 5bc20ce965504454aa5f406eb0d030dd 300 Gene3D G3DSA:3.40.190.10 183 267 6.5E-19 T 28-03-2018 CNX65_RS23960 5bc20ce965504454aa5f406eb0d030dd 300 Gene3D G3DSA:1.10.10.10 2 84 3.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23960 5bc20ce965504454aa5f406eb0d030dd 300 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 63 1.0E-11 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS22620 9be42852a4446036d9c6df3e241c7b1e 127 SUPERFAMILY SSF47413 7 68 8.59E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS22620 9be42852a4446036d9c6df3e241c7b1e 127 Gene3D G3DSA:1.10.260.40 2 79 7.8E-10 T 28-03-2018 CNX65_RS22620 9be42852a4446036d9c6df3e241c7b1e 127 Gene3D G3DSA:3.90.20.10 81 126 3.4E-5 T 28-03-2018 CNX65_RS22620 9be42852a4446036d9c6df3e241c7b1e 127 Pfam PF13560 Helix-turn-helix domain 14 71 2.4E-6 T 28-03-2018 CNX65_RS24335 61c3aee537cbe9d185bfc1c5308af946 278 SUPERFAMILY SSF53955 169 275 2.63E-15 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS24335 61c3aee537cbe9d185bfc1c5308af946 278 Gene3D G3DSA:1.10.530.10 116 277 1.8E-19 T 28-03-2018 CNX65_RS24335 61c3aee537cbe9d185bfc1c5308af946 278 Pfam PF01464 Transglycosylase SLT domain 185 263 1.2E-12 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CNX65_RS24465 0e5db0c0b9e651f934ababbc7abaeb82 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 2.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24465 0e5db0c0b9e651f934ababbc7abaeb82 196 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 2.3E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24465 0e5db0c0b9e651f934ababbc7abaeb82 196 SUPERFAMILY SSF46689 3 78 5.64E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS24465 0e5db0c0b9e651f934ababbc7abaeb82 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 61 2.0E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24465 0e5db0c0b9e651f934ababbc7abaeb82 196 Gene3D G3DSA:1.10.10.60 1 57 3.3E-17 T 28-03-2018 CNX65_RS24465 0e5db0c0b9e651f934ababbc7abaeb82 196 SUPERFAMILY SSF48498 85 187 2.67E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS24465 0e5db0c0b9e651f934ababbc7abaeb82 196 Gene3D G3DSA:1.10.357.10 58 188 6.7E-16 T 28-03-2018 CNX65_RS21540 e52e0d37690c145fca10e775d57a9dbb 284 SUPERFAMILY SSF46894 208 279 4.42E-13 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS21540 e52e0d37690c145fca10e775d57a9dbb 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 248 260 1.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21540 e52e0d37690c145fca10e775d57a9dbb 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 232 248 1.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21540 e52e0d37690c145fca10e775d57a9dbb 284 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 218 232 1.9E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21540 e52e0d37690c145fca10e775d57a9dbb 284 Gene3D G3DSA:1.10.10.10 163 284 2.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21540 e52e0d37690c145fca10e775d57a9dbb 284 Pfam PF00196 Bacterial regulatory proteins, luxR family 217 263 7.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21540 e52e0d37690c145fca10e775d57a9dbb 284 SMART SM00421 215 274 2.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 Gene3D G3DSA:3.30.565.10 163 318 2.1E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 Pfam PF00672 HAMP domain 53 97 1.4E-12 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 SMART SM00304 51 103 3.1E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 266 276 8.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 248 262 8.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 280 298 8.0E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 SMART SM00387 211 318 3.5E-36 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 SMART SM00388 104 168 2.1E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 SUPERFAMILY SSF158472 53 99 3.01E-10 T 28-03-2018 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 SUPERFAMILY SSF47384 87 168 1.22E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 Pfam PF00512 His Kinase A (phospho-acceptor) domain 105 168 5.6E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 SUPERFAMILY SSF55874 158 316 3.14E-40 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 Gene3D G3DSA:1.10.287.130 94 162 5.6E-15 T 28-03-2018 CNX65_RS30565 2ada0ab81f0fe77dce407b8ca6f17c23 323 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 212 316 1.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 Pfam PF01037 Lrp/AsnC ligand binding domain 84 151 3.6E-15 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 Pfam PF13412 Winged helix-turn-helix DNA-binding 15 62 4.4E-14 T 28-03-2018 CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 15 31 6.4E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 42 61 6.4E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 42 6.4E-11 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 Gene3D G3DSA:3.30.70.920 68 159 2.2E-20 T 28-03-2018 CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 SUPERFAMILY SSF46785 15 74 2.27E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 SMART SM00344 15 121 9.4E-32 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 SUPERFAMILY SSF54909 77 155 4.56E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS24690 82f12222d3bb70f10b5a30a4a8b62f37 162 Gene3D G3DSA:1.10.10.10 1 67 6.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25630 95ba555cad7f17f08b77f4bfea7499c8 380 SUPERFAMILY SSF101960 25 376 3.14E-90 T 28-03-2018 CNX65_RS25630 95ba555cad7f17f08b77f4bfea7499c8 380 Pfam PF01458 Uncharacterized protein family (UPF0051) 130 350 2.1E-74 T 28-03-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 CNX65_RS25630 95ba555cad7f17f08b77f4bfea7499c8 380 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 97 367 3.7E-78 T 28-03-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 PRINTS PR01703 Manganese superoxide dismutase signature 67 80 2.4E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 PRINTS PR01703 Manganese superoxide dismutase signature 120 128 2.4E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 PRINTS PR01703 Manganese superoxide dismutase signature 158 170 2.4E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 PRINTS PR01703 Manganese superoxide dismutase signature 7 18 2.4E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 PRINTS PR01703 Manganese superoxide dismutase signature 28 41 2.4E-17 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 84 1.9E-25 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 PIRSF PIRSF000349 1 203 2.1E-69 T 28-03-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 Gene3D G3DSA:1.10.287.990 21 84 1.2E-16 T 28-03-2018 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 SUPERFAMILY SSF46609 3 88 1.7E-26 T 28-03-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 SUPERFAMILY SSF54719 84 197 3.67E-41 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 160 167 - T 28-03-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS02505 2e4eabe3f2285ccc25df06277eed7666 209 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 91 193 1.1E-33 T 28-03-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803 CNX65_RS09890 a7c26b5064f3861554196edcd263a277 293 SUPERFAMILY SSF161098 56 277 1.96E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09890 a7c26b5064f3861554196edcd263a277 293 Gene3D G3DSA:1.10.3720.10 6 291 4.3E-36 T 28-03-2018 CNX65_RS09890 a7c26b5064f3861554196edcd263a277 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 286 2.4E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS19760 423a32cfe6588a12bf0a32ed851936b3 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 58 1.0E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19760 423a32cfe6588a12bf0a32ed851936b3 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19760 423a32cfe6588a12bf0a32ed851936b3 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19760 423a32cfe6588a12bf0a32ed851936b3 210 Gene3D G3DSA:1.10.10.60 3 58 1.9E-18 T 28-03-2018 CNX65_RS19760 423a32cfe6588a12bf0a32ed851936b3 210 SUPERFAMILY SSF46689 5 60 1.04E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS19760 423a32cfe6588a12bf0a32ed851936b3 210 ProSitePatterns PS01081 TetR-type HTH domain signature. 29 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS19760 423a32cfe6588a12bf0a32ed851936b3 210 Gene3D G3DSA:1.10.357.10 59 198 6.7E-27 T 28-03-2018 CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 ProSitePatterns PS01218 TatC family signature. 181 200 - T 28-03-2018 IPR019820 Sec-independent periplasmic protein translocase, conserved site CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 Pfam PF00902 Sec-independent protein translocase protein (TatC) 25 248 2.9E-59 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 23 254 1.6E-59 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 131 157 3.4E-35 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 181 209 3.4E-35 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 113 131 3.4E-35 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 22 49 3.4E-35 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CNX65_RS11465 d73e3c8fbfc04c17d82c3793bc02ed6e 370 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 17 268 16.892 T 28-03-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 Gene3D G3DSA:2.60.40.1180 529 578 0.0059 T 28-03-2018 CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 Gene3D G3DSA:2.60.120.260 50 215 2.1E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 Gene3D G3DSA:2.60.40.1180 679 826 4.6E-26 T 28-03-2018 CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 SUPERFAMILY SSF49899 634 722 3.89E-9 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 SUPERFAMILY SSF51445 201 542 1.1E-66 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 464 814 3.5E-41 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 SUPERFAMILY SSF49785 64 214 1.56E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 Gene3D G3DSA:3.20.20.80 216 528 1.7E-73 T 28-03-2018 CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 Pfam PF02018 Carbohydrate binding domain 64 199 1.9E-9 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CNX65_RS09275 f5962dbe6224f93eff4db894dae423c2 826 SMART SM00813 464 814 4.2E-51 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS31740 583ce027ca1fe78345d0203aaf4eed7a 339 Pfam PF03631 Virulence factor BrkB 38 291 3.8E-44 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS31740 583ce027ca1fe78345d0203aaf4eed7a 339 TIGRFAM TIGR00766 TIGR00766: inner membrane protein YhjD 24 290 1.8E-66 T 28-03-2018 IPR005274 Inner membrane protein YhjD CNX65_RS31740 583ce027ca1fe78345d0203aaf4eed7a 339 PIRSF PIRSF035875 8 305 1.2E-30 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 Pfam PF01039 Carboxyl transferase domain 250 368 5.0E-7 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 Pfam PF01039 Carboxyl transferase domain 35 147 3.8E-9 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 SUPERFAMILY SSF52096 203 405 5.19E-37 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 Gene3D G3DSA:3.90.226.10 18 197 2.0E-21 T 28-03-2018 CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 SUPERFAMILY SSF52096 10 186 1.53E-23 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 Gene3D G3DSA:3.90.226.10 205 396 1.6E-31 T 28-03-2018 CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 76 94 1.5E-11 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 42 56 1.5E-11 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CNX65_RS32150 42d5c582bb5fdb8e579ed8c03c9816c9 409 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 113 130 1.5E-11 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Pfam PF08531 Alpha-L-rhamnosidase N-terminal domain 145 313 9.2E-60 T 28-03-2018 IPR013737 Bacterial alpha-L-rhamnosidase N-terminal CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Gene3D G3DSA:2.60.40.10 15 112 5.8E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Pfam PF05592 Bacterial alpha-L-rhamnosidase concanavalin-like domain 324 408 1.4E-22 T 28-03-2018 IPR008902 Alpha-L-rhamnosidase, concanavalin-like domain CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Gene3D G3DSA:1.50.10.10 420 760 1.2E-52 T 28-03-2018 CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Pfam PF17390 Bacterial alpha-L-rhamnosidase C-terminal domain 767 838 4.7E-17 T 28-03-2018 IPR035398 Alpha-L-rhamnosidase C-terminal domain CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Gene3D G3DSA:2.60.120.260 305 418 8.3E-35 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 SUPERFAMILY SSF48208 419 830 4.56E-46 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Pfam PF17389 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain 421 765 6.5E-109 T 28-03-2018 IPR035396 Alpha-L-rhamnosidase, six-hairpin glycosidase domain CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Gene3D G3DSA:2.60.420.10 761 840 2.1E-23 T 28-03-2018 CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 PIRSF PIRSF010631 9 856 8.2E-229 T 28-03-2018 IPR016007 Alpha-L-rhamnosidase CNX65_RS10465 e469a3d2b66a7c24b11260752b08c7bb 859 Gene3D G3DSA:2.60.120.260 113 304 5.0E-58 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS30385 c1375412f22b62c2c923411b932895e9 78 SUPERFAMILY SSF48452 2 61 3.41E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30385 c1375412f22b62c2c923411b932895e9 78 Gene3D G3DSA:1.25.40.10 1 70 1.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS21470 2697d24a463faec164fc82338e0bf33f 373 Pfam PF13473 Cupredoxin-like domain 16 118 1.8E-8 T 28-03-2018 IPR028096 EfeO-type cupredoxin-like domain CNX65_RS21470 2697d24a463faec164fc82338e0bf33f 373 Pfam PF09375 Imelysin 136 363 5.1E-40 T 28-03-2018 IPR018976 Peptidase M75, Imelysin CNX65_RS33425 ca8ad5449366e62c7e818931301203e2 174 SUPERFAMILY SSF46785 3 166 2.26E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33425 ca8ad5449366e62c7e818931301203e2 174 Gene3D G3DSA:1.10.10.10 1 92 1.3E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33425 ca8ad5449366e62c7e818931301203e2 174 Pfam PF03551 Transcriptional regulator PadR-like family 7 76 1.7E-16 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS04715 d3fad7db585e185dde7d5baa6e5b1af7 487 Pfam PF00501 AMP-binding enzyme 141 341 1.2E-11 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS04715 d3fad7db585e185dde7d5baa6e5b1af7 487 Gene3D G3DSA:3.40.50.980 140 313 9.4E-20 T 28-03-2018 CNX65_RS04715 d3fad7db585e185dde7d5baa6e5b1af7 487 Pfam PF14535 AMP-binding enzyme C-terminal domain 391 474 3.0E-12 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal CNX65_RS04715 d3fad7db585e185dde7d5baa6e5b1af7 487 Gene3D G3DSA:3.30.300.30 381 476 2.9E-11 T 28-03-2018 CNX65_RS04715 d3fad7db585e185dde7d5baa6e5b1af7 487 SUPERFAMILY SSF56801 96 475 3.92E-54 T 28-03-2018 CNX65_RS04850 16c620771a6ffdfcc4896aad57611ec3 1102 SUPERFAMILY SSF52540 256 321 8.7E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04850 16c620771a6ffdfcc4896aad57611ec3 1102 SUPERFAMILY SSF52540 551 679 8.7E-23 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04850 16c620771a6ffdfcc4896aad57611ec3 1102 Pfam PF00271 Helicase conserved C-terminal domain 562 677 3.0E-6 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04850 16c620771a6ffdfcc4896aad57611ec3 1102 Gene3D G3DSA:3.40.50.300 543 715 4.0E-15 T 28-03-2018 CNX65_RS04850 16c620771a6ffdfcc4896aad57611ec3 1102 SMART SM00487 157 334 7.5E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS04850 16c620771a6ffdfcc4896aad57611ec3 1102 Gene3D G3DSA:3.40.50.10810 150 342 1.4E-22 T 28-03-2018 CNX65_RS04850 16c620771a6ffdfcc4896aad57611ec3 1102 SUPERFAMILY SSF52540 154 343 8.52E-30 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08755 237e31761d66ee710ce65d06f8319b2d 155 SUPERFAMILY SSF55729 27 153 3.04E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS08755 237e31761d66ee710ce65d06f8319b2d 155 Gene3D G3DSA:3.40.630.30 2 154 1.7E-28 T 28-03-2018 CNX65_RS08755 237e31761d66ee710ce65d06f8319b2d 155 Pfam PF00583 Acetyltransferase (GNAT) family 29 135 4.0E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 Pfam PF03704 Bacterial transcriptional activator domain 113 258 4.8E-25 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 SUPERFAMILY SSF46894 16 106 5.39E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 Pfam PF00486 Transcriptional regulatory protein, C terminal 37 106 1.1E-7 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 Gene3D G3DSA:1.25.40.10 115 260 3.0E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 SMART SM00862 30 106 1.0E-4 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 SUPERFAMILY SSF48452 108 259 4.64E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 Gene3D G3DSA:1.10.10.10 7 114 1.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19260 fd628a35905c711de7a7d2761d6b1286 261 SMART SM01043 113 258 2.9E-24 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS23800 971e4a99528e9002be29d28ac4c38a10 493 SUPERFAMILY SSF58104 119 363 1.48E-53 T 28-03-2018 CNX65_RS23800 971e4a99528e9002be29d28ac4c38a10 493 Gene3D G3DSA:1.10.287.950 170 370 2.5E-42 T 28-03-2018 CNX65_RS23800 971e4a99528e9002be29d28ac4c38a10 493 Gene3D G3DSA:1.10.287.950 54 169 5.2E-4 T 28-03-2018 CNX65_RS23800 971e4a99528e9002be29d28ac4c38a10 493 SMART SM00283 113 367 3.0E-41 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS23800 971e4a99528e9002be29d28ac4c38a10 493 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 175 333 2.4E-34 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS23800 971e4a99528e9002be29d28ac4c38a10 493 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 240 269 1.4E-5 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS23800 971e4a99528e9002be29d28ac4c38a10 493 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 141 170 1.4E-5 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS02175 b4dbee804a73b0ff2c6e2bffb2e401a0 222 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 125 213 9.1E-14 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CNX65_RS14720 2de8208c49d2746517909846b2264418 424 Gene3D G3DSA:3.40.190.10 31 206 2.3E-35 T 28-03-2018 CNX65_RS14720 2de8208c49d2746517909846b2264418 424 Gene3D G3DSA:3.40.190.10 207 373 5.8E-10 T 28-03-2018 CNX65_RS14720 2de8208c49d2746517909846b2264418 424 SUPERFAMILY SSF53850 26 418 6.62E-59 T 28-03-2018 CNX65_RS14720 2de8208c49d2746517909846b2264418 424 Pfam PF01547 Bacterial extracellular solute-binding protein 47 334 8.1E-35 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 SUPERFAMILY SSF57716 11 46 1.37E-11 T 28-03-2018 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 415 52.557 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 Gene3D G3DSA:1.10.8.60 317 409 6.5E-35 T 28-03-2018 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 SUPERFAMILY SSF52540 59 405 4.76E-74 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 317 395 8.5E-15 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 9 411 1.7E-195 T 28-03-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 SMART SM00382 113 269 1.1E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 SMART SM00994 10 49 1.1E-23 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 Pfam PF07724 AAA domain (Cdc48 subfamily) 114 310 1.6E-50 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 SMART SM01086 317 411 4.4E-34 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 Pfam PF06689 ClpX C4-type zinc finger 12 48 1.7E-20 T 28-03-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 CNX65_RS05755 770d814910847ed9dfc948f79fb0050a 426 Gene3D G3DSA:3.40.50.300 53 315 1.3E-67 T 28-03-2018 CNX65_RS04860 e939e24207f49c251980383162dfd5b0 349 Gene3D G3DSA:1.10.490.20 247 334 6.3E-6 T 28-03-2018 CNX65_RS04860 e939e24207f49c251980383162dfd5b0 349 Pfam PF02310 B12 binding domain 112 222 9.8E-17 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS04860 e939e24207f49c251980383162dfd5b0 349 SUPERFAMILY SSF52242 107 229 3.53E-20 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS04860 e939e24207f49c251980383162dfd5b0 349 Pfam PF02607 B12 binding domain 31 99 1.8E-6 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS04860 e939e24207f49c251980383162dfd5b0 349 Gene3D G3DSA:3.40.50.280 109 231 5.0E-24 T 28-03-2018 CNX65_RS23080 a038576e7d34dc032bd50623ef82773e 537 Gene3D G3DSA:3.40.50.980 182 344 1.4E-18 T 28-03-2018 CNX65_RS23080 a038576e7d34dc032bd50623ef82773e 537 Pfam PF00501 AMP-binding enzyme 48 434 7.8E-55 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS23080 a038576e7d34dc032bd50623ef82773e 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS23080 a038576e7d34dc032bd50623ef82773e 537 SUPERFAMILY SSF56801 47 526 1.14E-69 T 28-03-2018 CNX65_RS23080 a038576e7d34dc032bd50623ef82773e 537 Gene3D G3DSA:2.30.38.10 345 433 2.7E-15 T 28-03-2018 CNX65_RS23080 a038576e7d34dc032bd50623ef82773e 537 Gene3D G3DSA:3.30.300.30 442 529 9.2E-4 T 28-03-2018 CNX65_RS23080 a038576e7d34dc032bd50623ef82773e 537 Gene3D G3DSA:3.40.50.980 46 181 9.5E-25 T 28-03-2018 CNX65_RS24635 ae68cffb2e6506e232cfc2e3cb13f380 366 SUPERFAMILY SSF56801 51 317 8.77E-18 T 28-03-2018 CNX65_RS24635 ae68cffb2e6506e232cfc2e3cb13f380 366 Pfam PF00501 AMP-binding enzyme 194 316 2.0E-9 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS24635 ae68cffb2e6506e232cfc2e3cb13f380 366 Gene3D G3DSA:3.40.50.980 88 277 9.3E-16 T 28-03-2018 CNX65_RS34185 9ade6f9ba1451de51ed147552a3106a5 311 SUPERFAMILY SSF51430 2 308 1.26E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS34185 9ade6f9ba1451de51ed147552a3106a5 311 Pfam PF00248 Aldo/keto reductase family 14 308 3.7E-61 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS34185 9ade6f9ba1451de51ed147552a3106a5 311 Gene3D G3DSA:3.20.20.100 1 311 1.9E-80 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS22595 4d9b0f77294bc9da8dcafb314db00b5b 674 Pfam PF01580 FtsK/SpoIIIE family 325 490 8.7E-6 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CNX65_RS22595 4d9b0f77294bc9da8dcafb314db00b5b 674 Gene3D G3DSA:3.40.50.300 296 504 2.2E-5 T 28-03-2018 CNX65_RS22595 4d9b0f77294bc9da8dcafb314db00b5b 674 SUPERFAMILY SSF52540 260 540 6.9E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00385 1d30dc183ffed8fe1e76895251b49aeb 346 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 41 327 5.2E-42 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CNX65_RS00385 1d30dc183ffed8fe1e76895251b49aeb 346 SUPERFAMILY SSF51695 37 333 1.36E-60 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS00385 1d30dc183ffed8fe1e76895251b49aeb 346 Gene3D G3DSA:3.20.20.190 27 341 3.7E-67 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 77 88 3.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.1E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 239 1.6E-54 T 28-03-2018 CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 Gene3D G3DSA:3.40.50.720 156 239 6.8E-20 T 28-03-2018 CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 SUPERFAMILY SSF51735 3 241 4.03E-71 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 Gene3D G3DSA:3.40.50.720 3 155 5.0E-44 T 28-03-2018 CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 172 0.0064 T 28-03-2018 CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.0E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 1.0E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.0E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.0E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.0E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24890 0dd77575502eae49c78823e16ba43cad 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 223 1.0E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 Pfam PF00072 Response regulator receiver domain 3 115 1.9E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 SMART SM00448 1 114 3.1E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.4E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 Gene3D G3DSA:3.40.50.2300 1 132 2.2E-34 T 28-03-2018 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 SUPERFAMILY SSF46894 140 212 2.82E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 SUPERFAMILY SSF52172 2 132 1.29E-30 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 Gene3D G3DSA:1.10.10.10 133 210 2.6E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 ProSitePatterns PS00622 LuxR-type HTH domain signature. 165 192 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 204 7.6E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11355 dbd461cb1b8bc957193b73e180074d81 232 SMART SM00421 148 205 1.3E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS06995 ef5f5a0390eb49f167eecbb93129d8e7 331 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 13 316 5.5E-43 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS06995 ef5f5a0390eb49f167eecbb93129d8e7 331 Gene3D G3DSA:3.40.50.1100 49 150 6.9E-34 T 28-03-2018 CNX65_RS06995 ef5f5a0390eb49f167eecbb93129d8e7 331 PIRSF PIRSF006278 1 331 3.2E-118 T 28-03-2018 IPR027278 1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase CNX65_RS06995 ef5f5a0390eb49f167eecbb93129d8e7 331 SUPERFAMILY SSF53686 6 328 4.94E-94 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS06995 ef5f5a0390eb49f167eecbb93129d8e7 331 Gene3D G3DSA:3.40.50.1100 151 331 1.0E-25 T 28-03-2018 CNX65_RS06995 ef5f5a0390eb49f167eecbb93129d8e7 331 TIGRFAM TIGR01274 ACC_deam: 1-aminocyclopropane-1-carboxylate deaminase 3 331 1.7E-165 T 28-03-2018 IPR005965 1-aminocyclopropane-1-carboxylate deaminase GO:0008660|GO:0009310|GO:0030170 KEGG: 00270+3.5.99.7 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 Gene3D G3DSA:3.40.190.80 146 261 2.2E-25 T 28-03-2018 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 Pfam PF00459 Inositol monophosphatase family 8 239 2.6E-51 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 77 93 5.8E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 176 197 5.8E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 207 231 5.8E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 126 149 5.8E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 57 73 5.8E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 PRINTS PR00377 Inositol monophosphatase superfamily signature 35 55 5.8E-40 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 Gene3D G3DSA:3.30.540.10 1 145 1.3E-37 T 28-03-2018 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 210 224 - T 28-03-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 77 90 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CNX65_RS15260 1302a45f30fb4ead6f485288260fe99a 261 SUPERFAMILY SSF56655 5 258 1.11E-62 T 28-03-2018 CNX65_RS28830 c45d51ebe66a85b5ce4ed8019c968f65 265 Gene3D G3DSA:3.20.20.370 79 265 5.9E-31 T 28-03-2018 CNX65_RS28830 c45d51ebe66a85b5ce4ed8019c968f65 265 Pfam PF01522 Polysaccharide deacetylase 80 198 1.2E-21 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CNX65_RS28830 c45d51ebe66a85b5ce4ed8019c968f65 265 SUPERFAMILY SSF88713 48 258 1.05E-34 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS05985 bc0808158147c71d6cd5d1ce263160f9 280 Gene3D G3DSA:3.30.1180.10 151 278 3.0E-41 T 28-03-2018 CNX65_RS05985 bc0808158147c71d6cd5d1ce263160f9 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 276 6.6E-76 T 28-03-2018 IPR003797 DegV CNX65_RS05985 bc0808158147c71d6cd5d1ce263160f9 280 SUPERFAMILY SSF82549 2 276 8.89E-72 T 28-03-2018 CNX65_RS05985 bc0808158147c71d6cd5d1ce263160f9 280 Gene3D G3DSA:3.40.50.10170 1 150 6.2E-44 T 28-03-2018 CNX65_RS05985 bc0808158147c71d6cd5d1ce263160f9 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 274 9.7E-80 T 28-03-2018 IPR003797 DegV CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 SUPERFAMILY SSF51395 7 339 3.97E-93 T 28-03-2018 CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 Gene3D G3DSA:3.20.20.70 1 340 2.9E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 84 103 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 Pfam PF01180 Dihydroorotate dehydrogenase 49 339 7.7E-87 T 28-03-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 Hamap MF_00225 Dihydroorotate dehydrogenase (quinone) [pyrD]. 3 339 46.96 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 PIRSF PIRSF000164 17 341 2.2E-97 T 28-03-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 TIGRFAM TIGR01036 pyrD_sub2: dihydroorotate dehydrogenase (fumarate) 6 339 1.2E-116 T 28-03-2018 IPR005719 Dihydroorotate dehydrogenase, class 2 GO:0004152|GO:0006207|GO:0016020|GO:0055114 KEGG: 00240+1.3.5.2|MetaCyc: PWY-5686|Reactome: R-HSA-500753 CNX65_RS28380 b1f6829734985ca89377f9c6efa0fd1f 342 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 295 315 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CNX65_RS06050 4985ca2770e117e407365b050d668b0c 314 Pfam PF04168 A predicted alpha-helical domain with a conserved ER motif. 1 300 1.9E-78 T 28-03-2018 IPR007296 Domain of unknown function DUF403 CNX65_RS16250 4eb33365134049fec0d8db3afd8670de 299 Gene3D G3DSA:3.30.420.40 3 119 2.7E-14 T 28-03-2018 CNX65_RS16250 4eb33365134049fec0d8db3afd8670de 299 Gene3D G3DSA:3.30.420.40 120 298 5.9E-31 T 28-03-2018 CNX65_RS16250 4eb33365134049fec0d8db3afd8670de 299 Pfam PF00480 ROK family 10 294 2.2E-35 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS16250 4eb33365134049fec0d8db3afd8670de 299 SUPERFAMILY SSF53067 9 294 5.71E-34 T 28-03-2018 CNX65_RS08785 d20bb07347f9d1057fb03de494dc9605 341 Gene3D G3DSA:3.20.20.100 7 316 4.6E-93 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS08785 d20bb07347f9d1057fb03de494dc9605 341 Pfam PF00248 Aldo/keto reductase family 19 314 4.1E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS08785 d20bb07347f9d1057fb03de494dc9605 341 PRINTS PR00069 Aldo-keto reductase signature 42 66 7.7E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS08785 d20bb07347f9d1057fb03de494dc9605 341 PRINTS PR00069 Aldo-keto reductase signature 137 154 7.7E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS08785 d20bb07347f9d1057fb03de494dc9605 341 PRINTS PR00069 Aldo-keto reductase signature 106 124 7.7E-8 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS08785 d20bb07347f9d1057fb03de494dc9605 341 SUPERFAMILY SSF51430 6 316 1.07E-97 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 Gene3D G3DSA:3.40.50.10860 2 140 7.7E-29 T 28-03-2018 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 283 294 8.4E-12 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 174 194 8.4E-12 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 63 77 8.4E-12 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 130 152 8.4E-12 T 28-03-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 29 125 1.8E-10 T 28-03-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 SUPERFAMILY SSF53223 10 142 3.52E-26 T 28-03-2018 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 216 292 3.9E-8 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 PIRSF PIRSF000188 4 344 4.0E-90 T 28-03-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 SUPERFAMILY SSF51735 139 301 1.17E-35 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 Gene3D G3DSA:3.40.50.720 141 334 1.9E-30 T 28-03-2018 CNX65_RS21705 6293cb62dbccc14b27b132c26859d9ff 344 SMART SM00839 145 344 3.0E-21 T 28-03-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 CNX65_RS17390 3c4cc95ac91ba0494832c4c00be658ec 91 Pfam PF03861 ANTAR domain 28 80 4.5E-14 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS17390 3c4cc95ac91ba0494832c4c00be658ec 91 SMART SM01012 25 80 2.5E-13 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS17390 3c4cc95ac91ba0494832c4c00be658ec 91 Gene3D G3DSA:1.10.10.10 29 82 2.1E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06095 42853442321fa711ba1f3ea92886c3e5 526 Pfam PF05960 Bacterial protein of unknown function (DUF885) 1 518 2.0E-132 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 Gene3D G3DSA:1.10.1660.10 1 60 4.1E-21 T 28-03-2018 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 Pfam PF13411 MerR HTH family regulatory protein 6 72 4.7E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 SMART SM00422 5 74 5.1E-24 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 41 61 1.4E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 6 17 1.4E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 17 30 1.4E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 Gene3D G3DSA:1.10.1660.10 61 139 1.1E-8 T 28-03-2018 CNX65_RS22035 37330c09150db73978d3d80fada7b981 303 SUPERFAMILY SSF46955 5 106 1.76E-24 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS32845 2cf4a2c721e1b754451bacf3c221a8f1 347 Gene3D G3DSA:3.40.50.970 94 339 6.3E-40 T 28-03-2018 CNX65_RS32845 2cf4a2c721e1b754451bacf3c221a8f1 347 Gene3D G3DSA:3.40.50.970 14 93 3.9E-21 T 28-03-2018 CNX65_RS32845 2cf4a2c721e1b754451bacf3c221a8f1 347 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 67 214 7.0E-30 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CNX65_RS32845 2cf4a2c721e1b754451bacf3c221a8f1 347 SUPERFAMILY SSF52518 22 347 1.36E-80 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS23305 914cf1902af93f6157d5383acaec36af 219 Gene3D G3DSA:3.90.1720.10 14 189 3.8E-19 T 28-03-2018 CNX65_RS23305 914cf1902af93f6157d5383acaec36af 219 SUPERFAMILY SSF54001 15 201 5.79E-26 T 28-03-2018 CNX65_RS13960 b1ed56985a5ac23a0731106f06d43338 464 Gene3D G3DSA:1.20.1250.20 261 453 3.9E-28 T 28-03-2018 CNX65_RS13960 b1ed56985a5ac23a0731106f06d43338 464 Gene3D G3DSA:1.20.1250.20 9 226 6.8E-36 T 28-03-2018 CNX65_RS13960 b1ed56985a5ac23a0731106f06d43338 464 Pfam PF00083 Sugar (and other) transporter 54 450 1.9E-47 T 28-03-2018 IPR005828 Major facilitator, sugar transporter-like GO:0016021|GO:0022857|GO:0055085 CNX65_RS13960 b1ed56985a5ac23a0731106f06d43338 464 SUPERFAMILY SSF103473 7 449 3.27E-88 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13960 b1ed56985a5ac23a0731106f06d43338 464 ProSitePatterns PS00217 Sugar transport proteins signature 2. 115 140 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 Gene3D G3DSA:3.30.70.260 92 178 1.3E-17 T 28-03-2018 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 Gene3D G3DSA:1.10.150.210 193 239 5.7E-23 T 28-03-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 SUPERFAMILY SSF56784 180 389 4.2E-50 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 Pfam PF12710 haloacid dehalogenase-like hydrolase 183 349 2.4E-25 T 28-03-2018 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 182 350 1.3E-28 T 28-03-2018 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 SUPERFAMILY SSF55021 5 79 7.5E-10 T 28-03-2018 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 Gene3D G3DSA:3.30.70.260 1 90 8.4E-15 T 28-03-2018 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 169 384 2.1E-72 T 28-03-2018 CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 Gene3D G3DSA:3.40.50.1000 240 385 6.3E-28 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS04965 c14f20415c9758d075b8a3782c758103 406 Pfam PF13740 ACT domain 7 78 7.3E-20 T 28-03-2018 CNX65_RS06140 05e7a3b94ca5acf9c73e849a423764be 284 SUPERFAMILY SSF161098 77 263 3.92E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS06140 05e7a3b94ca5acf9c73e849a423764be 284 Gene3D G3DSA:1.10.3720.10 28 277 5.4E-26 T 28-03-2018 CNX65_RS06140 05e7a3b94ca5acf9c73e849a423764be 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 259 1.8E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS34525 fc080900cd805f908c0f9d6f25ad5094 278 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 254 6.4E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS34525 fc080900cd805f908c0f9d6f25ad5094 278 SUPERFAMILY SSF161098 53 244 2.13E-37 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS34525 fc080900cd805f908c0f9d6f25ad5094 278 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 54 149 2.7E-19 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CNX65_RS34525 fc080900cd805f908c0f9d6f25ad5094 278 Gene3D G3DSA:1.10.3720.10 3 251 3.9E-41 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 Gene3D G3DSA:3.40.50.300 87 244 1.8E-18 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 SUPERFAMILY SSF48452 532 726 2.46E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 SMART SM00530 10 65 6.1E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 SUPERFAMILY SSF52540 83 348 3.65E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 SMART SM00028 573 606 200.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 SMART SM00028 693 726 29.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 SMART SM00028 533 566 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 Gene3D G3DSA:1.10.260.40 1 79 1.2E-10 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 Gene3D G3DSA:1.10.150.200 516 583 5.9E-9 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 SUPERFAMILY SSF47413 6 62 9.78E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 Pfam PF13560 Helix-turn-helix domain 6 66 1.6E-9 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 Pfam PF00931 NB-ARC domain 99 353 3.4E-19 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 PRINTS PR00364 Disease resistance protein signature 282 296 2.3E-8 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 PRINTS PR00364 Disease resistance protein signature 118 133 2.3E-8 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 PRINTS PR00364 Disease resistance protein signature 197 211 2.3E-8 T 28-03-2018 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 Gene3D G3DSA:1.25.40.10 634 738 1.0E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS08170 9e9476341cdf0c07e997015c410acc46 742 Gene3D G3DSA:1.20.1250.10 584 633 0.018 T 28-03-2018 CNX65_RS14080 320072e363bf93836b0ef5926dd7bb21 294 Pfam PF03466 LysR substrate binding domain 93 293 1.6E-36 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS14080 320072e363bf93836b0ef5926dd7bb21 294 Gene3D G3DSA:1.10.10.10 1 88 5.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14080 320072e363bf93836b0ef5926dd7bb21 294 SUPERFAMILY SSF46785 3 116 8.71E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14080 320072e363bf93836b0ef5926dd7bb21 294 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 10 66 1.1E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS14080 320072e363bf93836b0ef5926dd7bb21 294 Gene3D G3DSA:3.40.190.10 190 269 5.8E-19 T 28-03-2018 CNX65_RS14080 320072e363bf93836b0ef5926dd7bb21 294 Gene3D G3DSA:3.40.190.10 95 189 1.2E-21 T 28-03-2018 CNX65_RS14080 320072e363bf93836b0ef5926dd7bb21 294 SUPERFAMILY SSF53850 95 292 5.02E-35 T 28-03-2018 CNX65_RS10940 7958f0c07f8db2be6ef2095166b5627d 214 SUPERFAMILY SSF53335 3 187 5.23E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS10940 7958f0c07f8db2be6ef2095166b5627d 214 Pfam PF05724 Thiopurine S-methyltransferase (TPMT) 1 213 3.6E-45 T 28-03-2018 IPR008854 TPMT family GO:0008757 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 CNX65_RS10940 7958f0c07f8db2be6ef2095166b5627d 214 Hamap MF_00812 Thiopurine S-methyltransferase [tpm]. 1 213 31.848 T 28-03-2018 IPR025835 Thiopurine S-methyltransferase GO:0008119 KEGG: 00983+2.1.1.67|Reactome: R-HSA-156581 CNX65_RS10940 7958f0c07f8db2be6ef2095166b5627d 214 Gene3D G3DSA:3.40.50.150 18 213 4.7E-18 T 28-03-2018 CNX65_RS26430 865021a197d6178afe8f369420a6f84b 447 Gene3D G3DSA:3.40.190.10 29 144 1.4E-7 T 28-03-2018 CNX65_RS26430 865021a197d6178afe8f369420a6f84b 447 Gene3D G3DSA:3.40.190.10 145 443 8.0E-37 T 28-03-2018 CNX65_RS26430 865021a197d6178afe8f369420a6f84b 447 SUPERFAMILY SSF53850 18 440 1.92E-67 T 28-03-2018 CNX65_RS26430 865021a197d6178afe8f369420a6f84b 447 Pfam PF01547 Bacterial extracellular solute-binding protein 44 337 2.4E-47 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS15800 ba79966e1b6bbea7a916532f2e99e2b7 109 Gene3D G3DSA:1.10.287.1060 6 103 1.0E-12 T 28-03-2018 CNX65_RS15800 ba79966e1b6bbea7a916532f2e99e2b7 109 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 7 98 1.1E-12 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CNX65_RS12465 29d56b6258e4a607d1f9b23198781e6e 331 SUPERFAMILY SSF161098 107 317 2.35E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12465 29d56b6258e4a607d1f9b23198781e6e 331 Gene3D G3DSA:1.10.3720.10 5 318 3.4E-38 T 28-03-2018 CNX65_RS12465 29d56b6258e4a607d1f9b23198781e6e 331 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 130 329 1.1E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS19815 043fbcf132efcee00c284e8e07eb6299 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 9 63 2.6E-17 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS19815 043fbcf132efcee00c284e8e07eb6299 288 Gene3D G3DSA:1.10.10.10 5 84 8.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19815 043fbcf132efcee00c284e8e07eb6299 288 SUPERFAMILY SSF46785 8 87 2.72E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10910 2838e4d0c763f31188ad7a359e0ef6f2 191 SUPERFAMILY SSF51069 5 187 3.4E-32 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CNX65_RS10910 2838e4d0c763f31188ad7a359e0ef6f2 191 Gene3D G3DSA:3.10.200.10 3 190 1.1E-27 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CNX65_RS10910 2838e4d0c763f31188ad7a359e0ef6f2 191 SMART SM01057 3 187 4.3E-10 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CNX65_RS10910 2838e4d0c763f31188ad7a359e0ef6f2 191 Pfam PF00194 Eukaryotic-type carbonic anhydrase 7 94 2.4E-6 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CNX65_RS10910 2838e4d0c763f31188ad7a359e0ef6f2 191 Pfam PF00194 Eukaryotic-type carbonic anhydrase 113 178 2.2E-11 T 28-03-2018 IPR001148 Alpha carbonic anhydrase CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 ProSitePatterns PS00622 LuxR-type HTH domain signature. 867 894 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 Pfam PF00196 Bacterial regulatory proteins, luxR family 852 903 1.1E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 Gene3D G3DSA:1.10.10.10 248 372 0.18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 Gene3D G3DSA:3.40.50.300 3 187 6.7E-13 T 28-03-2018 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 SUPERFAMILY SSF48452 587 721 1.68E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 SMART SM00421 850 907 4.3E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 883 895 7.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 867 883 7.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 853 867 7.7E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 SUPERFAMILY SSF52540 84 246 4.86E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 SUPERFAMILY SSF52540 7 52 4.86E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 Gene3D G3DSA:1.10.10.10 861 905 2.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 Gene3D G3DSA:1.25.40.10 538 860 9.1E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 Pfam PF13191 AAA ATPase domain 3 156 2.0E-15 T 28-03-2018 CNX65_RS13650 354923c64d61b350dcedbfca20e5b183 933 SUPERFAMILY SSF46894 843 903 3.3E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS02950 11f5ba0534bca1efb1e8f388c074c740 487 SUPERFAMILY SSF52540 210 457 4.6E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02950 11f5ba0534bca1efb1e8f388c074c740 487 Gene3D G3DSA:3.40.50.300 213 464 8.8E-13 T 28-03-2018 CNX65_RS02950 11f5ba0534bca1efb1e8f388c074c740 487 Pfam PF01580 FtsK/SpoIIIE family 241 413 8.7E-10 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CNX65_RS01050 19902a386b445d6aece403bf20193249 158 Gene3D G3DSA:1.20.1260.10 2 158 3.1E-41 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS01050 19902a386b445d6aece403bf20193249 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 40 56 4.2E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CNX65_RS01050 19902a386b445d6aece403bf20193249 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 135 153 4.2E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CNX65_RS01050 19902a386b445d6aece403bf20193249 158 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 64 80 4.2E-11 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CNX65_RS01050 19902a386b445d6aece403bf20193249 158 Pfam PF00210 Ferritin-like domain 22 156 8.2E-22 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CNX65_RS01050 19902a386b445d6aece403bf20193249 158 SUPERFAMILY SSF47240 6 156 8.97E-48 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS01050 19902a386b445d6aece403bf20193249 158 PIRSF PIRSF005900 2 158 2.4E-43 T 28-03-2018 IPR002177 DNA-binding protein Dps GO:0006950|GO:0055114 CNX65_RS01050 19902a386b445d6aece403bf20193249 158 ProSitePatterns PS00818 Dps protein family signature 1. 40 56 - T 28-03-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 CNX65_RS32625 1658367ba81f76a525dcfa122b524754 54 ProSitePatterns PS00582 Ribosomal protein L33 signature. 22 41 - T 28-03-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32625 1658367ba81f76a525dcfa122b524754 54 Pfam PF00471 Ribosomal protein L33 9 54 4.2E-22 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32625 1658367ba81f76a525dcfa122b524754 54 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 6 54 19.734 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32625 1658367ba81f76a525dcfa122b524754 54 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 54 9.9E-21 T 28-03-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32625 1658367ba81f76a525dcfa122b524754 54 SUPERFAMILY SSF57829 4 54 2.87E-19 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Gene3D G3DSA:3.40.50.80 457 590 1.1E-27 T 28-03-2018 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 SUPERFAMILY SSF50475 161 277 5.02E-12 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Pfam PF00175 Oxidoreductase NAD-binding domain 478 576 4.9E-12 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Gene3D G3DSA:2.30.110.10 25 142 0.027 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 SUPERFAMILY SSF52343 457 595 1.83E-32 T 28-03-2018 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00406 Cytochrome B5 reductase signature 565 573 5.9E-10 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00406 Cytochrome B5 reductase signature 477 496 5.9E-10 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00406 Cytochrome B5 reductase signature 514 525 5.9E-10 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00406 Cytochrome B5 reductase signature 418 425 5.9E-10 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00406 Cytochrome B5 reductase signature 454 468 5.9E-10 T 28-03-2018 IPR001834 NADH:cytochrome b5 reductase (CBR) GO:0016491|GO:0055114 Reactome: R-HSA-1237044 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 SUPERFAMILY SSF54292 587 696 1.84E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Gene3D G3DSA:3.10.20.30 591 698 3.7E-21 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 161 252 6.8E-9 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 623 688 1.3E-10 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 SUPERFAMILY SSF63380 372 469 1.0E-26 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Pfam PF00970 Oxidoreductase FAD-binding domain 375 467 1.2E-10 T 28-03-2018 IPR008333 Oxidoreductase, FAD-binding domain Reactome: R-HSA-1237044 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Gene3D G3DSA:2.30.110.10 157 305 1.2E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 Gene3D G3DSA:2.40.30.10 359 456 1.0E-21 T 28-03-2018 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 418 425 5.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 514 525 5.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CNX65_RS22235 6d8b66ada0259239bb6405604795510b 699 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 477 496 5.3E-5 T 28-03-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 CNX65_RS26165 f18c5a44ef63924feed5e59adf8be9c2 152 Gene3D G3DSA:2.70.70.10 1 152 7.2E-51 T 28-03-2018 CNX65_RS26165 f18c5a44ef63924feed5e59adf8be9c2 152 SUPERFAMILY SSF51261 4 149 3.49E-38 T 28-03-2018 IPR011055 Duplicated hybrid motif CNX65_RS26165 f18c5a44ef63924feed5e59adf8be9c2 152 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 4 126 3.5E-41 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CNX65_RS26165 f18c5a44ef63924feed5e59adf8be9c2 152 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 67 79 - T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CNX65_RS26165 f18c5a44ef63924feed5e59adf8be9c2 152 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 6 123 2.7E-31 T 28-03-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 Gene3D G3DSA:3.40.50.2300 170 330 3.7E-47 T 28-03-2018 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 SUPERFAMILY SSF53822 59 330 1.96E-65 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 Gene3D G3DSA:1.10.260.40 3 55 9.1E-17 T 28-03-2018 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 Gene3D G3DSA:3.40.50.2300 56 169 1.2E-25 T 28-03-2018 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 47 2.9E-14 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 SMART SM00354 2 69 7.9E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 Pfam PF13377 Periplasmic binding protein-like domain 171 327 2.4E-35 T 28-03-2018 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 SUPERFAMILY SSF47413 3 49 1.19E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 6.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS05630 2c5358f3f4e79163aba662c041d6d2cb 337 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 6.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS04215 3a1081e4ab2baee088c94a20f52aca38 122 SMART SM00028 4 37 2.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04215 3a1081e4ab2baee088c94a20f52aca38 122 SMART SM00028 38 71 75.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04215 3a1081e4ab2baee088c94a20f52aca38 122 SMART SM00028 72 105 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04215 3a1081e4ab2baee088c94a20f52aca38 122 Gene3D G3DSA:1.25.40.10 1 121 1.0E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04215 3a1081e4ab2baee088c94a20f52aca38 122 Pfam PF14559 Tetratricopeptide repeat 16 79 1.0E-8 T 28-03-2018 CNX65_RS04215 3a1081e4ab2baee088c94a20f52aca38 122 SUPERFAMILY SSF48452 3 104 3.8E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13730 1a66277b908bd76f6976a1796a0568d5 93 Pfam PF14117 Domain of unknown function (DUF4287) 2 63 5.6E-25 T 28-03-2018 IPR025629 Protein of unknown function DUF4287 CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 SMART SM00487 19 214 2.4E-26 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 Gene3D G3DSA:3.40.50.300 208 349 3.7E-29 T 28-03-2018 CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 15 343 7.6E-104 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 Pfam PF00271 Helicase conserved C-terminal domain 231 323 3.7E-14 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 Pfam PF16124 RecQ zinc-binding 418 466 4.8E-9 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 Pfam PF00270 DEAD/DEAH box helicase 25 184 6.8E-17 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 SUPERFAMILY SSF52540 63 343 1.62E-51 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 Gene3D G3DSA:1.10.10.10 412 525 8.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 137 146 - T 28-03-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 Gene3D G3DSA:3.40.50.300 4 204 3.9E-30 T 28-03-2018 CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 SMART SM00490 248 324 1.3E-21 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS21225 6bd53752c688718962b4e3c14c7cc4b7 536 Gene3D G3DSA:1.10.10.10 350 411 0.0014 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13535 b1845ac3ed2cb57f3fb3b67e2246c277 200 SUPERFAMILY SSF53335 18 200 5.58E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS13535 b1845ac3ed2cb57f3fb3b67e2246c277 200 Gene3D G3DSA:3.40.50.150 3 200 6.0E-32 T 28-03-2018 CNX65_RS13535 b1845ac3ed2cb57f3fb3b67e2246c277 200 Pfam PF13649 Methyltransferase domain 50 146 1.1E-13 T 28-03-2018 CNX65_RS18665 fcadab95edce1a59e839b469ead2ddfb 425 Pfam PF07158 Dicarboxylate carrier protein MatC N-terminus 3 146 4.4E-33 T 28-03-2018 IPR009827 Dicarboxylate carrier MatC N-terminal CNX65_RS18665 fcadab95edce1a59e839b469ead2ddfb 425 Pfam PF03600 Citrate transporter 240 418 4.7E-8 T 28-03-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 CNX65_RS05885 1dd1dd9f5aee9620e3575214b52c4eda 177 Gene3D G3DSA:1.20.950.20 5 91 5.7E-4 T 28-03-2018 CNX65_RS05885 1dd1dd9f5aee9620e3575214b52c4eda 177 Pfam PF01794 Ferric reductase like transmembrane component 13 133 1.3E-10 T 28-03-2018 IPR013130 Ferric reductase transmembrane component-like domain CNX65_RS26555 f0cc39a1a0149711766b6b34c71af375 206 Gene3D G3DSA:1.20.1260.10 47 206 2.5E-33 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS26555 f0cc39a1a0149711766b6b34c71af375 206 Pfam PF03713 Domain of unknown function (DUF305) 59 204 6.4E-33 T 28-03-2018 IPR005183 Domain of unknown function DUF305 CNX65_RS08230 26113270cc28dd4a3176aa2b37b6cc32 1131 SUPERFAMILY SSF53822 775 1122 1.1E-7 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS08230 26113270cc28dd4a3176aa2b37b6cc32 1131 Gene3D G3DSA:3.40.50.300 14 304 3.4E-7 T 28-03-2018 CNX65_RS08230 26113270cc28dd4a3176aa2b37b6cc32 1131 SUPERFAMILY SSF52540 20 61 7.42E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08230 26113270cc28dd4a3176aa2b37b6cc32 1131 Gene3D G3DSA:3.40.50.2300 727 949 2.4E-11 T 28-03-2018 CNX65_RS09140 4e4fec2073801b1ee66f5bfa0b291d5d 133 SUPERFAMILY SSF54909 17 109 1.13E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS09140 4e4fec2073801b1ee66f5bfa0b291d5d 133 Gene3D G3DSA:3.30.70.1060 1 130 4.1E-34 T 28-03-2018 CNX65_RS09140 4e4fec2073801b1ee66f5bfa0b291d5d 133 Pfam PF03795 YCII-related domain 26 102 3.9E-8 T 28-03-2018 IPR005545 YCII-related CNX65_RS01785 1d64aa78821d4e1c7980aa1209fde24a 419 Gene3D G3DSA:3.40.190.10 223 371 3.8E-15 T 28-03-2018 CNX65_RS01785 1d64aa78821d4e1c7980aa1209fde24a 419 Gene3D G3DSA:3.40.190.10 35 212 1.3E-32 T 28-03-2018 CNX65_RS01785 1d64aa78821d4e1c7980aa1209fde24a 419 SUPERFAMILY SSF53850 35 407 2.33E-81 T 28-03-2018 CNX65_RS01785 1d64aa78821d4e1c7980aa1209fde24a 419 Pfam PF13416 Bacterial extracellular solute-binding protein 53 355 2.6E-47 T 28-03-2018 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Gene3D G3DSA:1.10.150.310 496 625 3.3E-41 T 28-03-2018 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Pfam PF12836 Helix-hairpin-helix motif 488 552 1.3E-27 T 28-03-2018 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Pfam PF16921 Tex protein YqgF-like domain 323 448 3.2E-51 T 28-03-2018 IPR032639 Tex protein, YqgF-like domain CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 SUPERFAMILY SSF53098 318 466 1.82E-49 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Gene3D G3DSA:1.10.3500.10 351 495 3.8E-39 T 28-03-2018 IPR023323 Tex-like domain CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Gene3D G3DSA:2.40.50.140 638 720 1.2E-24 T 28-03-2018 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 SUPERFAMILY SSF47781 467 555 2.22E-26 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 SUPERFAMILY SSF158832 3 317 9.81E-115 T 28-03-2018 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 SUPERFAMILY SSF47781 557 626 3.78E-17 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Pfam PF00575 S1 RNA binding domain 644 715 5.0E-19 T 28-03-2018 IPR003029 S1 domain GO:0003676 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Gene3D G3DSA:1.10.3500.10 102 350 1.5E-76 T 28-03-2018 IPR023323 Tex-like domain CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Pfam PF09371 Tex-like protein N-terminal domain 9 190 5.7E-66 T 28-03-2018 IPR018974 Tex-like protein, N-terminal CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 Gene3D G3DSA:1.10.10.650 2 101 2.3E-32 T 28-03-2018 IPR023319 Tex-like protein, HTH domain CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 SMART SM00732 322 421 3.4E-39 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 SUPERFAMILY SSF50249 632 719 1.49E-24 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS08780 6fb85c326671529582d7986b42eb1ae1 779 SMART SM00316 644 715 2.1E-24 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS20005 7ac9140f00972cebb6a4b6fafb8250ec 309 Gene3D G3DSA:3.60.20.10 3 212 2.0E-62 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS20005 7ac9140f00972cebb6a4b6fafb8250ec 309 Gene3D G3DSA:1.25.40.10 213 300 2.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20005 7ac9140f00972cebb6a4b6fafb8250ec 309 SUPERFAMILY SSF56235 6 214 5.02E-53 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS20005 7ac9140f00972cebb6a4b6fafb8250ec 309 Pfam PF06267 Family of unknown function (DUF1028) 6 202 1.7E-53 T 28-03-2018 IPR010430 Protein of unknown function DUF1028 CNX65_RS22935 4612f4117b7487e76ff7d312bb93c043 425 Pfam PF06824 Metal-independent alpha-mannosidase (GH125) 25 412 2.1E-126 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CNX65_RS22935 4612f4117b7487e76ff7d312bb93c043 425 SUPERFAMILY SSF48208 21 417 1.4E-143 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS22935 4612f4117b7487e76ff7d312bb93c043 425 Gene3D G3DSA:1.50.10.10 2 422 7.2E-136 T 28-03-2018 CNX65_RS22935 4612f4117b7487e76ff7d312bb93c043 425 PIRSF PIRSF028846 1 425 1.6E-152 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CNX65_RS22935 4612f4117b7487e76ff7d312bb93c043 425 SMART SM01149 20 414 4.7E-228 T 28-03-2018 IPR008313 Metal-independent alpha-mannosidase CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 ProSitePatterns PS00893 Nudix box signature. 38 59 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 Gene3D G3DSA:3.90.79.10 2 141 1.7E-32 T 28-03-2018 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 SUPERFAMILY SSF53254 135 282 7.07E-17 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 137 217 2.5E-11 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 SMART SM00855 136 251 1.9E-8 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 PRINTS PR00502 NUDIX hydrolase family signature 33 47 3.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 PRINTS PR00502 NUDIX hydrolase family signature 47 62 3.1E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 SUPERFAMILY SSF55811 7 129 2.71E-28 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 Pfam PF00293 NUDIX domain 10 121 2.1E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS29515 e1d6a6214b16687db8feb6bf8ef07e4a 314 Gene3D G3DSA:3.40.50.1240 142 290 1.7E-20 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS24840 bb61d1d74b909d58ee99dd50e6921f34 310 Pfam PF13560 Helix-turn-helix domain 35 94 2.0E-7 T 28-03-2018 CNX65_RS24840 bb61d1d74b909d58ee99dd50e6921f34 310 SMART SM00530 38 93 2.3E-5 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS24840 bb61d1d74b909d58ee99dd50e6921f34 310 Gene3D G3DSA:1.10.260.40 25 111 1.7E-10 T 28-03-2018 CNX65_RS24840 bb61d1d74b909d58ee99dd50e6921f34 310 SUPERFAMILY SSF47413 34 89 4.44E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS20975 1e7a5c5e50e2922baef8c1163a1f7079 158 Pfam PF13463 Winged helix DNA-binding domain 36 100 2.2E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS20975 1e7a5c5e50e2922baef8c1163a1f7079 158 SMART SM00347 25 127 7.2E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS20975 1e7a5c5e50e2922baef8c1163a1f7079 158 SUPERFAMILY SSF46785 17 141 4.87E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20975 1e7a5c5e50e2922baef8c1163a1f7079 158 Gene3D G3DSA:1.10.10.10 3 141 7.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34830 eebc78d9d905201eb1f04a451490bc17 260 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 108 203 1.6E-19 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS34830 eebc78d9d905201eb1f04a451490bc17 260 SUPERFAMILY SSF55073 112 251 7.77E-24 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS34830 eebc78d9d905201eb1f04a451490bc17 260 SMART SM00267 95 260 3.3E-15 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS34830 eebc78d9d905201eb1f04a451490bc17 260 Gene3D G3DSA:3.30.70.270 104 260 5.1E-31 T 28-03-2018 CNX65_RS34830 eebc78d9d905201eb1f04a451490bc17 260 Pfam PF00990 Diguanylate cyclase, GGDEF domain 109 209 3.5E-23 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS31190 22d57c5b763bb9852e88f1e9003ff873 285 Pfam PF00535 Glycosyl transferase family 2 10 191 7.4E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS31190 22d57c5b763bb9852e88f1e9003ff873 285 SUPERFAMILY SSF53448 8 134 4.19E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31190 22d57c5b763bb9852e88f1e9003ff873 285 SUPERFAMILY SSF53448 167 241 4.19E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31190 22d57c5b763bb9852e88f1e9003ff873 285 Gene3D G3DSA:3.90.550.10 3 267 2.1E-38 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1510 656 775 2.0E-16 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1510 2646 2763 4.0E-7 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1510 3380 3499 1.1E-15 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1510 2520 2645 4.1E-17 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1510 901 1026 3.7E-21 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1510 1401 1527 7.7E-16 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1510 3017 3134 2.5E-12 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.740 527 655 5.8E-16 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 3135 3260 1.9E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 1149 1277 7.8E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 2764 2898 1.1E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1220 2045 2138 8.8E-13 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1220 3276 3365 1.9E-15 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.1220 2294 2386 1.7E-15 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 3515 3601 4.5E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 911 989 1.9E-11 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 534 622 1.2E-11 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 1412 1499 2.0E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 667 735 3.8E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 3271 3343 2.0E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 1282 1375 6.8E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 1919 1995 1.1E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 1539 1629 3.3E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 2787 2864 2.4E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 2411 2486 1.9E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 3751 3841 7.4E-15 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 377 501 2.5E-12 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 3389 3479 1.2E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 1036 1120 3.5E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Pfam PF01345 Domain of unknown function DUF11 1664 1757 6.8E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 388 432 4.5E-10 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2414 2446 3.3E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1919 1957 1.2E-5 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 916 958 4.9E-10 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3753 3803 7.7E-14 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 536 586 2.9E-10 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1038 1083 2.2E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3273 3313 5.0E-9 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 678 709 9.5E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1668 1713 1.0E-8 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 2162 2198 4.2E-4 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1540 1588 1.2E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1416 1456 6.6E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 1286 1334 1.2E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 785 833 1.7E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 3515 3555 2.8E-7 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.740 370 511 1.8E-18 T 28-03-2018 CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 SUPERFAMILY SSF49401 389 502 5.72E-5 T 28-03-2018 IPR008966 Adhesion domain CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 2399 2518 1.9E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 1027 1148 1.1E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 2152 2274 2.7E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 3505 3624 9.2E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 3746 3884 1.9E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 1908 2025 7.2E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 1655 1778 6.7E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 776 899 1.6E-12 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 1278 1399 1.5E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 2899 3016 6.8E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 3625 3744 2.4E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 1782 1904 1.0E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12575 afa02d0e2ff4e5461aaad427b7ac500f 3924 Gene3D G3DSA:2.60.40.10 1531 1653 4.5E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 Gene3D G3DSA:3.40.190.10 203 256 0.069 T 28-03-2018 CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 3.8E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 SUPERFAMILY SSF46785 3 83 4.33E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 Gene3D G3DSA:3.40.190.10 176 202 0.0061 T 28-03-2018 CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 Gene3D G3DSA:1.10.10.10 1 76 1.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 SUPERFAMILY SSF53850 99 278 6.52E-16 T 28-03-2018 CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 Pfam PF03466 LysR substrate binding domain 99 278 2.6E-15 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS04225 e16adbddff9049f25253043a89f485be 295 Gene3D G3DSA:3.40.190.10 77 175 2.5E-13 T 28-03-2018 CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 Pfam PF10502 Signal peptidase, peptidase S26 138 242 4.2E-7 T 28-03-2018 IPR019533 Peptidase S26 CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 46 244 1.8E-34 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 Pfam PF00717 Peptidase S24-like 67 113 5.2E-6 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 ProSitePatterns PS00761 Signal peptidases I signature 3. 204 217 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 SUPERFAMILY SSF51306 59 111 1.41E-38 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 SUPERFAMILY SSF51306 143 251 1.41E-38 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 199 218 2.1E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 148 160 2.1E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 60 76 2.1E-18 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29050 f941acf24653cf24cbe3432ae828807d 299 Gene3D G3DSA:2.10.109.10 56 259 1.2E-39 T 28-03-2018 CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 SUPERFAMILY SSF141868 434 682 1.26E-81 T 28-03-2018 IPR001633 EAL domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 SUPERFAMILY SSF55073 260 417 1.1E-42 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 Gene3D G3DSA:3.30.450.20 96 255 1.5E-36 T 28-03-2018 CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 SUPERFAMILY SSF55785 117 242 3.22E-30 T 28-03-2018 IPR000014 PAS domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 SMART SM00086 202 244 8.3E-8 T 28-03-2018 IPR001610 PAC motif CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 SMART SM00052 425 676 4.1E-107 T 28-03-2018 IPR001633 EAL domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 SMART SM00091 129 195 3.5E-11 T 28-03-2018 IPR000014 PAS domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 252 413 1.2E-34 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 Pfam PF00990 Diguanylate cyclase, GGDEF domain 255 410 7.7E-41 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 Gene3D G3DSA:3.20.20.450 423 683 2.0E-102 T 28-03-2018 IPR001633 EAL domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 SMART SM00267 244 415 3.3E-56 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 Pfam PF00563 EAL domain 434 671 7.9E-70 T 28-03-2018 IPR001633 EAL domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 125 251 1.1E-28 T 28-03-2018 IPR000014 PAS domain CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 Gene3D G3DSA:3.30.70.270 256 422 8.6E-57 T 28-03-2018 CNX65_RS33960 bd16902b0eda53f578b3c20da265cb12 683 Pfam PF13426 PAS domain 141 243 6.8E-15 T 28-03-2018 IPR000014 PAS domain CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 Gene3D G3DSA:3.90.550.10 2 308 1.9E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 SUPERFAMILY SSF53448 12 61 1.88E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 SUPERFAMILY SSF53448 99 257 1.88E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 PRINTS PR01217 Proline rich extensin signature 506 527 1.3E-10 T 28-03-2018 CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 PRINTS PR01217 Proline rich extensin signature 558 575 1.3E-10 T 28-03-2018 CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 PRINTS PR01217 Proline rich extensin signature 608 633 1.3E-10 T 28-03-2018 CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 PRINTS PR01217 Proline rich extensin signature 415 427 1.3E-10 T 28-03-2018 CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 PRINTS PR01217 Proline rich extensin signature 540 556 1.3E-10 T 28-03-2018 CNX65_RS31145 0ee47af1295f43602dfe63edf6bf8d8a 1330 Pfam PF13641 Glycosyltransferase like family 2 15 259 1.4E-10 T 28-03-2018 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 SUPERFAMILY SSF53850 86 296 1.27E-42 T 28-03-2018 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 Gene3D G3DSA:1.10.10.10 1 83 2.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 Pfam PF03466 LysR substrate binding domain 86 291 7.9E-44 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 Gene3D G3DSA:3.40.190.10 176 267 2.9E-20 T 28-03-2018 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 6.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 6.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 6.0E-9 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 61 8.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 Gene3D G3DSA:3.40.190.10 86 175 6.7E-21 T 28-03-2018 CNX65_RS05740 b829c0100b5c76035075aaa95909201d 302 SUPERFAMILY SSF46785 1 109 8.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32590 fb58fc185162ef36718638594e6a87a9 136 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 83 111 - T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32590 fb58fc185162ef36718638594e6a87a9 136 Gene3D G3DSA:1.20.5.1030 80 131 3.7E-20 T 28-03-2018 CNX65_RS32590 fb58fc185162ef36718638594e6a87a9 136 Hamap MF_00422 Protein translocase subunit SecE [secE]. 78 133 13.019 T 28-03-2018 IPR022943 Preprotein translocase subunit SecE Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32590 fb58fc185162ef36718638594e6a87a9 136 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 80 136 3.4E-19 T 28-03-2018 IPR005807 SecE subunit of protein translocation complex GO:0009306|GO:0015450|GO:0016021 CNX65_RS32590 fb58fc185162ef36718638594e6a87a9 136 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 82 134 1.2E-18 T 28-03-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS21975 42c420f5c3ced437ec7ad40437d1b52c 429 Gene3D G3DSA:1.20.1250.20 14 210 2.2E-17 T 28-03-2018 CNX65_RS21975 42c420f5c3ced437ec7ad40437d1b52c 429 Pfam PF07690 Major Facilitator Superfamily 46 286 5.3E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS21975 42c420f5c3ced437ec7ad40437d1b52c 429 Gene3D G3DSA:1.20.1250.20 218 415 2.4E-23 T 28-03-2018 CNX65_RS21975 42c420f5c3ced437ec7ad40437d1b52c 429 SUPERFAMILY SSF103473 30 412 1.31E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS21215 81987450149ddea91c82c72bf1aaf7e9 298 Pfam PF04072 Leucine carboxyl methyltransferase 16 194 3.5E-49 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CNX65_RS21215 81987450149ddea91c82c72bf1aaf7e9 298 Gene3D G3DSA:3.40.50.150 1 271 9.0E-52 T 28-03-2018 CNX65_RS21215 81987450149ddea91c82c72bf1aaf7e9 298 SUPERFAMILY SSF53335 12 293 2.55E-66 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS21215 81987450149ddea91c82c72bf1aaf7e9 298 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 14 273 7.1E-71 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 Gene3D G3DSA:1.10.3810.10 58 270 4.4E-72 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 Pfam PF00905 Penicillin binding protein transpeptidase domain 360 633 2.4E-22 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 SUPERFAMILY SSF53955 55 275 3.94E-69 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 SMART SM00740 710 773 3.8E-12 T 28-03-2018 IPR005543 PASTA domain CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 SUPERFAMILY SSF56601 235 257 5.45E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 SUPERFAMILY SSF56601 533 706 5.45E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 SUPERFAMILY SSF56601 293 503 5.45E-72 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 Pfam PF00912 Transglycosylase 66 253 1.2E-60 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 Gene3D G3DSA:3.40.710.10 287 755 1.1E-72 T 28-03-2018 CNX65_RS01110 cfda47db1c477592317eb50abd78d044 830 Pfam PF03793 PASTA domain 715 773 3.1E-10 T 28-03-2018 IPR005543 PASTA domain CNX65_RS32820 c663681ea1809d5daeb371e8a16b4a4b 347 SUPERFAMILY SSF46785 29 127 1.59E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32820 c663681ea1809d5daeb371e8a16b4a4b 347 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 30 95 7.8E-12 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS32820 c663681ea1809d5daeb371e8a16b4a4b 347 Gene3D G3DSA:1.10.10.10 17 119 1.6E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20460 b796e9a779e55d5e10c258b5ca34abc2 421 Gene3D G3DSA:1.20.1250.20 211 395 2.0E-16 T 28-03-2018 CNX65_RS20460 b796e9a779e55d5e10c258b5ca34abc2 421 Gene3D G3DSA:1.20.1250.20 12 206 1.4E-20 T 28-03-2018 CNX65_RS20460 b796e9a779e55d5e10c258b5ca34abc2 421 Pfam PF07690 Major Facilitator Superfamily 26 339 1.5E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS20460 b796e9a779e55d5e10c258b5ca34abc2 421 SUPERFAMILY SSF103473 16 396 8.24E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:1.25.40.10 715 766 1.6E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SUPERFAMILY SSF46894 6 91 5.95E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SUPERFAMILY SSF48452 715 869 1.23E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:1.25.40.10 899 1087 9.8E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SUPERFAMILY SSF48452 955 1068 8.43E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Pfam PF13424 Tetratricopeptide repeat 718 788 5.6E-8 T 28-03-2018 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SUPERFAMILY SSF52540 270 534 5.35E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SUPERFAMILY SSF48452 883 988 2.2E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:3.30.70.100 808 841 3.7E-4 T 28-03-2018 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SUPERFAMILY SSF48452 94 263 5.9E-40 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Pfam PF00931 NB-ARC domain 285 540 9.5E-13 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:3.40.50.300 267 425 5.5E-18 T 28-03-2018 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00862 19 92 2.7E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Pfam PF03704 Bacterial transcriptional activator domain 99 244 1.9E-42 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 PRINTS PR00364 Disease resistance protein signature 376 390 2.2E-9 T 28-03-2018 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 PRINTS PR00364 Disease resistance protein signature 464 478 2.2E-9 T 28-03-2018 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 PRINTS PR00364 Disease resistance protein signature 298 313 2.2E-9 T 28-03-2018 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:1.25.40.10 101 266 8.2E-31 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:1.25.40.10 842 898 2.4E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00028 759 792 0.047 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00028 194 227 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00028 879 912 36.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00028 799 832 37.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00028 718 751 52.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00028 999 1032 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM00028 959 992 120.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Pfam PF00486 Transcriptional regulatory protein, C terminal 28 87 4.2E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 SMART SM01043 99 244 6.6E-48 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:1.10.10.10 10 100 4.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:1.10.10.10 523 580 8.8E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00960 f3911175bafc9c1e4015261a9a9df894 1088 Gene3D G3DSA:1.10.150.200 767 807 2.5E-10 T 28-03-2018 CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 SUPERFAMILY SSF51735 15 266 1.49E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 29 266 1.9E-55 T 28-03-2018 CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 Gene3D G3DSA:3.40.50.720 58 267 8.2E-54 T 28-03-2018 CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 Gene3D G3DSA:3.40.50.720 12 57 1.8E-8 T 28-03-2018 CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 4.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 96 107 4.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 4.5E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 96 107 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 229 249 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23045 52dfbec875957c632e8cc68811d0e65e 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 21 38 1.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS14820 02d91a0f1194fdeb43002e902b875a04 141 Pfam PF06841 T4-like virus tail tube protein gp19 9 139 5.2E-33 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 CNX65_RS14820 02d91a0f1194fdeb43002e902b875a04 141 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 9 139 3.5E-26 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 CNX65_RS14305 0d965f9ea53bded1dfa3ccab90f857ce 291 Gene3D G3DSA:3.40.390.10 16 269 6.6E-5 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CNX65_RS14305 0d965f9ea53bded1dfa3ccab90f857ce 291 SUPERFAMILY SSF55486 150 284 3.67E-9 T 28-03-2018 CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 Gene3D G3DSA:2.60.40.1180 486 531 1.4E-4 T 28-03-2018 CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 SUPERFAMILY SSF51445 16 465 1.22E-120 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 Gene3D G3DSA:3.20.20.470 4 107 4.8E-33 T 28-03-2018 CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 Pfam PF00128 Alpha amylase, catalytic domain 40 383 4.4E-81 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 Gene3D G3DSA:3.20.20.470 185 351 2.0E-36 T 28-03-2018 CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 SMART SM00642 25 408 1.3E-115 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 Pfam PF11941 Domain of unknown function (DUF3459) 454 530 2.7E-7 T 28-03-2018 IPR022567 Glycosyl hydrolase, C-terminal (DUF3459) CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 Gene3D G3DSA:3.90.400.10 117 184 2.6E-31 T 28-03-2018 CNX65_RS05645 00a3339d3453e0eb74997a57578098dd 531 Gene3D G3DSA:3.20.20.80 352 470 2.6E-23 T 28-03-2018 CNX65_RS25880 273d0ae5745c55f6f556290976fa6efb 328 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 306 29.001 T 28-03-2018 IPR003802 Sporulation regulator WhiA GO:0043937 CNX65_RS25880 273d0ae5745c55f6f556290976fa6efb 328 Gene3D G3DSA:3.10.28.10 115 199 0.036 T 28-03-2018 IPR027434 Homing endonuclease GO:0004519 CNX65_RS25880 273d0ae5745c55f6f556290976fa6efb 328 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 304 1.4E-104 T 28-03-2018 IPR033981 Sporulation regulator WhiA-like CNX65_RS25880 273d0ae5745c55f6f556290976fa6efb 328 Pfam PF02650 WhiA C-terminal HTH domain 221 303 7.4E-19 T 28-03-2018 IPR023054 Sporulation regulator WhiA, C-terminal CNX65_RS25880 273d0ae5745c55f6f556290976fa6efb 328 Pfam PF14527 WhiA LAGLIDADG-like domain 127 218 7.3E-24 T 28-03-2018 CNX65_RS25880 273d0ae5745c55f6f556290976fa6efb 328 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 20 104 9.4E-25 T 28-03-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain CNX65_RS13505 f9c558b2c91b6561c57699eaa73dd9b5 617 Gene3D G3DSA:3.40.190.10 230 336 5.3E-6 T 28-03-2018 CNX65_RS13505 f9c558b2c91b6561c57699eaa73dd9b5 617 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 93 492 1.8E-32 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS13505 f9c558b2c91b6561c57699eaa73dd9b5 617 SUPERFAMILY SSF53850 232 612 7.06E-55 T 28-03-2018 CNX65_RS13505 f9c558b2c91b6561c57699eaa73dd9b5 617 SUPERFAMILY SSF53850 30 199 7.06E-55 T 28-03-2018 CNX65_RS13505 f9c558b2c91b6561c57699eaa73dd9b5 617 Gene3D G3DSA:3.10.105.10 337 582 6.1E-27 T 28-03-2018 CNX65_RS13505 f9c558b2c91b6561c57699eaa73dd9b5 617 Gene3D G3DSA:3.90.76.10 44 201 7.2E-13 T 28-03-2018 CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 Gene3D G3DSA:3.30.300.30 461 597 2.3E-15 T 28-03-2018 CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 Pfam PF00501 AMP-binding enzyme 25 466 2.0E-96 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 Gene3D G3DSA:2.30.38.10 387 459 2.7E-22 T 28-03-2018 CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 Gene3D G3DSA:3.40.50.980 13 188 2.3E-39 T 28-03-2018 CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 SUPERFAMILY SSF56801 336 595 4.06E-113 T 28-03-2018 CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 SUPERFAMILY SSF56801 17 287 4.06E-113 T 28-03-2018 CNX65_RS22250 1a81432489d2469d5e3a459a138c865b 597 Gene3D G3DSA:3.40.50.980 189 386 1.1E-36 T 28-03-2018 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 SUPERFAMILY SSF46689 10 81 7.98E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 64 7.8E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 Pfam PF00440 Bacterial regulatory proteins, tetR family 210 256 4.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 SUPERFAMILY SSF46689 197 280 3.39E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 3.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 18 31 3.9E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 Gene3D G3DSA:1.10.357.10 252 384 8.6E-11 T 28-03-2018 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 Gene3D G3DSA:1.10.10.60 191 251 3.3E-17 T 28-03-2018 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 Gene3D G3DSA:1.10.10.60 1 51 5.0E-18 T 28-03-2018 CNX65_RS23325 2027f44c1c2175bb6b32bdec9bc349c8 385 Gene3D G3DSA:1.10.10.60 52 185 2.0E-9 T 28-03-2018 CNX65_RS22820 5f3a61f2a6e317410f75de3df2d9db1c 485 Gene3D G3DSA:3.40.50.980 1 149 6.8E-36 T 28-03-2018 CNX65_RS22820 5f3a61f2a6e317410f75de3df2d9db1c 485 SUPERFAMILY SSF56801 1 483 8.63E-119 T 28-03-2018 CNX65_RS22820 5f3a61f2a6e317410f75de3df2d9db1c 485 Gene3D G3DSA:2.30.38.10 299 388 4.5E-25 T 28-03-2018 CNX65_RS22820 5f3a61f2a6e317410f75de3df2d9db1c 485 Gene3D G3DSA:3.30.300.30 389 485 3.2E-16 T 28-03-2018 CNX65_RS22820 5f3a61f2a6e317410f75de3df2d9db1c 485 Pfam PF00501 AMP-binding enzyme 6 396 3.9E-88 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS22820 5f3a61f2a6e317410f75de3df2d9db1c 485 Gene3D G3DSA:3.40.50.980 150 298 4.7E-33 T 28-03-2018 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 15 178 6.0E-44 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 SUPERFAMILY SSF50891 15 179 1.9E-59 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 137 152 1.7E-25 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 28 43 1.7E-25 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 69 81 1.7E-25 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 109 124 1.7E-25 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 124 136 1.7E-25 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 Gene3D G3DSA:2.40.100.10 2 182 4.2E-60 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 64 81 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CNX65_RS00545 7d3c583af9f91e2006bee86a33e3dfc9 182 PIRSF PIRSF001467 2 182 3.6E-55 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CNX65_RS31170 e9d9d5789683352334f91e8f19334d0a 181 Pfam PF00293 NUDIX domain 48 170 7.6E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS31170 e9d9d5789683352334f91e8f19334d0a 181 Gene3D G3DSA:3.90.79.10 33 181 7.4E-24 T 28-03-2018 CNX65_RS31170 e9d9d5789683352334f91e8f19334d0a 181 SUPERFAMILY SSF55811 46 178 1.62E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS25730 8c265a438f91322357f2c8a20d30fabf 139 Pfam PF04341 Protein of unknown function, DUF485 45 132 4.3E-29 T 28-03-2018 IPR007436 Protein of unknown function DUF485 CNX65_RS25730 8c265a438f91322357f2c8a20d30fabf 139 Gene3D G3DSA:1.20.1250.20 46 124 8.1E-4 T 28-03-2018 CNX65_RS03610 6269a2a3eb57d94d8b83f6f3c0ecb62b 69 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 4 45 3.0E-11 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS03610 6269a2a3eb57d94d8b83f6f3c0ecb62b 69 PIRSF PIRSF006488 1 69 3.6E-23 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS03610 6269a2a3eb57d94d8b83f6f3c0ecb62b 69 Gene3D G3DSA:1.10.287.1040 3 66 6.8E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS03610 6269a2a3eb57d94d8b83f6f3c0ecb62b 69 Pfam PF02609 Exonuclease VII small subunit 6 56 2.5E-17 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS03610 6269a2a3eb57d94d8b83f6f3c0ecb62b 69 SUPERFAMILY SSF116842 2 59 6.93E-16 T 28-03-2018 CNX65_RS03610 6269a2a3eb57d94d8b83f6f3c0ecb62b 69 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 6 59 1.7E-20 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS03610 6269a2a3eb57d94d8b83f6f3c0ecb62b 69 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 5 65 13.848 T 28-03-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 CNX65_RS01105 317fe8d52f642ab4b72100ba6f9a4e6f 155 SUPERFAMILY SSF89095 4 154 2.56E-33 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CNX65_RS01105 317fe8d52f642ab4b72100ba6f9a4e6f 155 Gene3D G3DSA:1.10.1510.10 2 93 2.7E-26 T 28-03-2018 CNX65_RS01105 317fe8d52f642ab4b72100ba6f9a4e6f 155 Pfam PF09424 Yqey-like protein 5 153 3.5E-45 T 28-03-2018 IPR019004 Uncharacterised domain YOR215C, mitochondrial CNX65_RS01105 317fe8d52f642ab4b72100ba6f9a4e6f 155 Gene3D G3DSA:1.10.10.410 94 154 1.4E-17 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CNX65_RS19240 1da6eebca1729cafd5b83e0b9c07dd2f 385 Pfam PF07690 Major Facilitator Superfamily 18 213 1.2E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS19240 1da6eebca1729cafd5b83e0b9c07dd2f 385 Pfam PF07690 Major Facilitator Superfamily 228 377 2.7E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS19240 1da6eebca1729cafd5b83e0b9c07dd2f 385 SUPERFAMILY SSF103473 9 379 4.97E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19240 1da6eebca1729cafd5b83e0b9c07dd2f 385 Gene3D G3DSA:1.20.1250.20 200 382 2.9E-12 T 28-03-2018 CNX65_RS19240 1da6eebca1729cafd5b83e0b9c07dd2f 385 Gene3D G3DSA:1.20.1250.20 8 199 3.2E-23 T 28-03-2018 CNX65_RS19240 1da6eebca1729cafd5b83e0b9c07dd2f 385 PRINTS PR01036 Tetracycline resistance protein TetB signature 134 158 1.7E-8 T 28-03-2018 CNX65_RS19240 1da6eebca1729cafd5b83e0b9c07dd2f 385 PRINTS PR01036 Tetracycline resistance protein TetB signature 104 124 1.7E-8 T 28-03-2018 CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 SMART SM00862 143 212 9.9E-16 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 SMART SM00448 1 110 3.4E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 Gene3D G3DSA:3.40.50.2300 1 122 1.4E-31 T 28-03-2018 CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 212 9.6E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 SUPERFAMILY SSF46894 123 212 1.5E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 Gene3D G3DSA:1.10.10.10 123 214 3.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 SUPERFAMILY SSF52172 1 116 1.08E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS21780 a4d67e20e2555bf514c944b4f105b6f3 215 Pfam PF00072 Response regulator receiver domain 2 110 1.7E-23 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 SMART SM00490 222 319 2.9E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 Pfam PF08482 ATP-dependent helicase C-terminal 641 764 3.0E-44 T 28-03-2018 IPR013689 ATP-dependent RNA helicase HrpB, C-terminal CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 SUPERFAMILY SSF52540 19 329 2.72E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 SMART SM00847 379 473 1.6E-7 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 Pfam PF04408 Helicase associated domain (HA2) 381 436 1.4E-8 T 28-03-2018 IPR007502 Helicase-associated domain GO:0004386 CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 PIRSF PIRSF005496 2 772 8.2E-243 T 28-03-2018 CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 Gene3D G3DSA:3.40.50.300 176 338 4.8E-38 T 28-03-2018 CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 SMART SM00487 1 185 3.6E-16 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 TIGRFAM TIGR01970 DEAH_box_HrpB: ATP-dependent helicase HrpB 6 771 8.2E-206 T 28-03-2018 IPR010225 ATP-dependent helicase HrpB GO:0008026 CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 Gene3D G3DSA:3.40.50.300 5 158 7.3E-21 T 28-03-2018 CNX65_RS04690 a764bc5e4de7279d5f82ce51e5b36639 772 Pfam PF00271 Helicase conserved C-terminal domain 206 317 7.2E-12 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS02460 76474aec507fd0fd4cba7099fbc5ecab 546 SUPERFAMILY SSF103473 164 523 1.16E-23 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS02460 76474aec507fd0fd4cba7099fbc5ecab 546 Pfam PF07690 Major Facilitator Superfamily 150 476 7.7E-14 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS02460 76474aec507fd0fd4cba7099fbc5ecab 546 Gene3D G3DSA:1.20.1250.20 330 525 1.5E-7 T 28-03-2018 CNX65_RS02460 76474aec507fd0fd4cba7099fbc5ecab 546 Gene3D G3DSA:1.20.1250.20 144 329 6.1E-14 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SUPERFAMILY SSF48452 559 751 1.52E-30 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SMART SM00028 641 674 0.016 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SMART SM00028 601 634 3.1E-4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SMART SM00028 681 714 1.1 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SMART SM00028 561 594 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SMART SM00028 721 754 63.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:1.25.40.10 714 763 1.6E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SMART SM00530 25 87 0.0032 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:3.40.50.300 117 269 7.9E-13 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:1.10.260.40 19 87 1.9E-4 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Pfam PF13424 Tetratricopeptide repeat 561 633 1.9E-12 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Pfam PF13424 Tetratricopeptide repeat 642 711 3.4E-13 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:1.10.150.200 545 609 6.2E-10 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:1.10.150.200 636 685 2.3E-10 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:1.10.10.10 367 435 0.0061 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 PRINTS PR00364 Disease resistance protein signature 151 166 4.2E-7 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 PRINTS PR00364 Disease resistance protein signature 230 244 4.2E-7 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 PRINTS PR00364 Disease resistance protein signature 318 332 4.2E-7 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:3.30.70.100 686 713 2.0E-6 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 Gene3D G3DSA:3.30.70.100 610 635 2.1E-9 T 28-03-2018 CNX65_RS04905 8548f8fe9ca2e7bc9f18fcc95e09463c 775 SUPERFAMILY SSF52540 114 380 1.04E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS20590 cd3291df8bcb426cafc80dca5a164a71 248 Pfam PF00106 short chain dehydrogenase 8 170 9.1E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20590 cd3291df8bcb426cafc80dca5a164a71 248 Gene3D G3DSA:3.40.50.720 1 245 4.5E-28 T 28-03-2018 CNX65_RS20590 cd3291df8bcb426cafc80dca5a164a71 248 SUPERFAMILY SSF51735 1 232 2.49E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 SUPERFAMILY SSF47203 245 401 4.51E-44 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 Gene3D G3DSA:2.40.110.10 133 235 6.1E-35 T 28-03-2018 CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 Gene3D G3DSA:1.10.540.10 1 132 4.4E-29 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 128 1.8E-11 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 SUPERFAMILY SSF56645 2 260 1.31E-62 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 Gene3D G3DSA:1.20.140.10 236 402 3.5E-47 T 28-03-2018 CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 247 397 2.9E-35 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS17565 ddc86094494f17a905659daaa3f0afdf 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 235 4.7E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS23595 7922a605401e336d4c76a3d5f4a32fc8 476 SUPERFAMILY SSF52467 301 474 2.29E-71 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS23595 7922a605401e336d4c76a3d5f4a32fc8 476 PIRSF PIRSF000204 1 475 4.7E-182 T 28-03-2018 IPR012136 NADP transhydrogenase, beta subunit GO:0008750|GO:0016021|GO:0050661|GO:0055114 KEGG: 00760+1.6.1.2 CNX65_RS23595 7922a605401e336d4c76a3d5f4a32fc8 476 Pfam PF02233 NAD(P) transhydrogenase beta subunit 8 471 6.7E-173 T 28-03-2018 IPR034300 NADP transhydrogenase beta-like domain KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CNX65_RS23595 7922a605401e336d4c76a3d5f4a32fc8 476 Gene3D G3DSA:3.40.50.1220 300 474 2.1E-82 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS19175 d700e46d14c7fdd24bae87b82864d26c 338 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 120 3.0E-8 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS19175 d700e46d14c7fdd24bae87b82864d26c 338 Gene3D G3DSA:3.30.360.10 136 325 2.7E-9 T 28-03-2018 CNX65_RS19175 d700e46d14c7fdd24bae87b82864d26c 338 Gene3D G3DSA:3.40.50.720 1 135 4.3E-18 T 28-03-2018 CNX65_RS19175 d700e46d14c7fdd24bae87b82864d26c 338 SUPERFAMILY SSF51735 1 150 1.48E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19175 d700e46d14c7fdd24bae87b82864d26c 338 SUPERFAMILY SSF55347 131 281 2.16E-5 T 28-03-2018 CNX65_RS26325 bfef616273a38e658cf2ce298cb5bfa3 610 Pfam PF13304 AAA domain, putative AbiEii toxin, Type IV TA system 316 364 9.3E-7 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS26325 bfef616273a38e658cf2ce298cb5bfa3 610 SUPERFAMILY SSF52540 210 367 3.37E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26325 bfef616273a38e658cf2ce298cb5bfa3 610 SUPERFAMILY SSF52540 2 168 3.37E-18 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26325 bfef616273a38e658cf2ce298cb5bfa3 610 Gene3D G3DSA:3.40.50.300 2 377 4.3E-23 T 28-03-2018 CNX65_RS00180 98eed0a1d5ca6c5e72b6be48ea2b729a 388 Pfam PF07690 Major Facilitator Superfamily 31 263 8.2E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS00180 98eed0a1d5ca6c5e72b6be48ea2b729a 388 Gene3D G3DSA:1.20.1250.20 192 385 1.3E-25 T 28-03-2018 CNX65_RS00180 98eed0a1d5ca6c5e72b6be48ea2b729a 388 SUPERFAMILY SSF103473 2 385 4.71E-43 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS00180 98eed0a1d5ca6c5e72b6be48ea2b729a 388 Gene3D G3DSA:1.20.1250.20 1 190 2.4E-19 T 28-03-2018 CNX65_RS13915 fb6d9745234721fd1c8359e71d30ec8c 292 SUPERFAMILY SSF52540 2 223 8.7E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13915 fb6d9745234721fd1c8359e71d30ec8c 292 Gene3D G3DSA:3.40.50.300 1 231 1.8E-67 T 28-03-2018 CNX65_RS13915 fb6d9745234721fd1c8359e71d30ec8c 292 SMART SM00382 26 205 5.1E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13915 fb6d9745234721fd1c8359e71d30ec8c 292 Pfam PF13732 Domain of unknown function (DUF4162) 211 292 6.1E-13 T 28-03-2018 IPR025302 Domain of unknown function DUF4162 CNX65_RS13915 fb6d9745234721fd1c8359e71d30ec8c 292 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS13915 fb6d9745234721fd1c8359e71d30ec8c 292 Pfam PF00005 ABC transporter 17 157 6.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 4 364 1.1E-110 T 28-03-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 Gene3D G3DSA:3.30.1360.120 134 236 1.8E-32 T 28-03-2018 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 Gene3D G3DSA:4.10.1250.10 237 280 1.3E-17 T 28-03-2018 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 SUPERFAMILY SSF101790 277 364 3.43E-25 T 28-03-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal domain CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 Gene3D G3DSA:2.40.30.110 282 365 4.4E-26 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 358 9.1E-26 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 Hamap MF_00259 Aminomethyltransferase [gcvT]. 2 364 43.862 T 28-03-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 PIRSF PIRSF006487 1 365 2.6E-102 T 28-03-2018 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 Pfam PF01571 Aminomethyltransferase folate-binding domain 8 258 1.0E-92 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 Gene3D G3DSA:3.30.1360.120 3 133 4.7E-31 T 28-03-2018 CNX65_RS27725 3e4a439d2e05e87db83b774f99dcb1ad 365 SUPERFAMILY SSF103025 3 281 5.18E-97 T 28-03-2018 CNX65_RS28475 4f5e48c26afd697c8beeee2232ecc9fb 129 PIRSF PIRSF008459 2 129 2.7E-30 T 28-03-2018 IPR016540 Uncharacterised conserved protein UCP008459 CNX65_RS28475 4f5e48c26afd697c8beeee2232ecc9fb 129 Gene3D G3DSA:3.30.2130.10 1 129 6.0E-28 T 28-03-2018 CNX65_RS28475 4f5e48c26afd697c8beeee2232ecc9fb 129 SUPERFAMILY SSF55021 62 126 6.48E-17 T 28-03-2018 CNX65_RS28475 4f5e48c26afd697c8beeee2232ecc9fb 129 Pfam PF13840 ACT domain 59 120 5.7E-18 T 28-03-2018 IPR027795 GATS-like ACT domain CNX65_RS28475 4f5e48c26afd697c8beeee2232ecc9fb 129 SUPERFAMILY SSF55021 4 58 1.83E-10 T 28-03-2018 CNX65_RS01465 a1194e94fec2ed7a890c47faadda9086 786 Pfam PF03030 Inorganic H+ pyrophosphatase 29 710 4.8E-238 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CNX65_RS01465 a1194e94fec2ed7a890c47faadda9086 786 PIRSF PIRSF001265 14 723 1.1E-248 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CNX65_RS01465 a1194e94fec2ed7a890c47faadda9086 786 Hamap MF_01129 Putative K(+)-stimulated pyrophosphate-energized sodium pump [hppA]. 17 715 24.131 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CNX65_RS01465 a1194e94fec2ed7a890c47faadda9086 786 TIGRFAM TIGR01104 V_PPase: V-type H(+)-translocating pyrophosphatase 22 716 2.6E-206 T 28-03-2018 IPR004131 Pyrophosphate-energised proton pump GO:0004427|GO:0009678|GO:0015992|GO:0016020 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 SMART SM00382 60 231 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 SUPERFAMILY SSF52540 7 270 8.63E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 7 327 9.8E-175 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 Gene3D G3DSA:3.30.250.10 272 329 1.9E-26 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 Hamap MF_00268 Protein RecA [recA]. 8 332 53.054 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 Pfam PF00154 recA bacterial DNA recombination protein 10 271 5.8E-143 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 SUPERFAMILY SSF54752 271 329 2.62E-21 T 28-03-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 Gene3D G3DSA:3.40.50.300 29 271 3.6E-49 T 28-03-2018 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 PRINTS PR00142 RecA protein signature 300 317 8.4E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 PRINTS PR00142 RecA protein signature 130 159 8.4E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 PRINTS PR00142 RecA protein signature 246 275 8.4E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 PRINTS PR00142 RecA protein signature 213 241 8.4E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 PRINTS PR00142 RecA protein signature 96 125 8.4E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 PRINTS PR00142 RecA protein signature 168 197 8.4E-86 T 28-03-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 CNX65_RS07030 0c3b7933b3142350b78abf1165efdb1f 347 ProSitePatterns PS00321 recA signature. 216 224 - T 28-03-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 CNX65_RS27280 a003c89a079d8211e18d6f0011c3b42d 128 SUPERFAMILY SSF55298 4 127 2.04E-37 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS27280 a003c89a079d8211e18d6f0011c3b42d 128 Gene3D G3DSA:3.30.1330.40 1 128 3.6E-41 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS27280 a003c89a079d8211e18d6f0011c3b42d 128 Pfam PF01042 Endoribonuclease L-PSP 9 126 4.4E-32 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CNX65_RS27280 a003c89a079d8211e18d6f0011c3b42d 128 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 6 126 1.2E-32 T 28-03-2018 IPR006056 RidA family CNX65_RS11030 342498824e5be14cacef660df76f548c 328 Pfam PF02470 MlaD protein 39 116 1.2E-16 T 28-03-2018 IPR003399 Mce/MlaD CNX65_RS11030 342498824e5be14cacef660df76f548c 328 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 174 286 1.8E-7 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CNX65_RS11030 342498824e5be14cacef660df76f548c 328 Gene3D G3DSA:1.20.120.330 141 297 5.1E-4 T 28-03-2018 CNX65_RS11030 342498824e5be14cacef660df76f548c 328 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 9 304 5.6E-59 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS10030 3996bee7bddc585ccd7c550822f2113e 395 Pfam PF07730 Histidine kinase 207 269 1.0E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS10030 3996bee7bddc585ccd7c550822f2113e 395 SUPERFAMILY SSF55874 289 394 1.51E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10030 3996bee7bddc585ccd7c550822f2113e 395 Gene3D G3DSA:3.30.565.10 277 395 1.5E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS21425 789f5235d71f8f9f48f3f2e753fc5095 199 Gene3D G3DSA:1.10.10.60 3 67 4.6E-20 T 28-03-2018 CNX65_RS21425 789f5235d71f8f9f48f3f2e753fc5095 199 Gene3D G3DSA:1.10.357.10 68 199 6.5E-19 T 28-03-2018 CNX65_RS21425 789f5235d71f8f9f48f3f2e753fc5095 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 26 39 9.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21425 789f5235d71f8f9f48f3f2e753fc5095 199 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 9.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21425 789f5235d71f8f9f48f3f2e753fc5095 199 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 2.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21425 789f5235d71f8f9f48f3f2e753fc5095 199 SUPERFAMILY SSF46689 12 96 3.49E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21425 789f5235d71f8f9f48f3f2e753fc5095 199 SUPERFAMILY SSF48498 91 195 2.22E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS13605 c6ff6662134b5f2ce3facc7ac4b6f63e 82 Pfam PF00550 Phosphopantetheine attachment site 19 70 2.2E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13605 c6ff6662134b5f2ce3facc7ac4b6f63e 82 ProSitePatterns PS00012 Phosphopantetheine attachment site. 31 46 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS13605 c6ff6662134b5f2ce3facc7ac4b6f63e 82 Gene3D G3DSA:1.10.1200.10 3 80 6.8E-13 T 28-03-2018 CNX65_RS13605 c6ff6662134b5f2ce3facc7ac4b6f63e 82 SUPERFAMILY SSF47336 5 79 1.83E-15 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 SMART SM00876 248 340 1.1E-24 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 PIRSF PIRSF001619 16 346 7.5E-100 T 28-03-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 SMART SM00729 72 277 3.2E-32 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 Hamap MF_01694 Biotin synthase [bioB]. 32 341 36.798 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 Gene3D G3DSA:3.20.20.70 21 332 4.9E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 248 336 3.2E-10 T 28-03-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 TIGRFAM TIGR00433 bioB: biotin synthase 44 338 6.6E-101 T 28-03-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 Pfam PF04055 Radical SAM superfamily 79 227 7.1E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS28120 54822c7a8335d0872206a5fa27ab8190 347 SUPERFAMILY SSF102114 32 329 1.03E-60 T 28-03-2018 CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 Gene3D G3DSA:1.10.260.40 39 59 4.0E-11 T 28-03-2018 CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 23 53 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 SUPERFAMILY SSF46689 4 83 6.48E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 SUPERFAMILY SSF48498 82 191 3.66E-7 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 Gene3D G3DSA:1.10.357.10 60 191 3.1E-14 T 28-03-2018 CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 9.9E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS28495 30569e4ee206e04ab11372e15efbec42 195 Gene3D G3DSA:1.10.10.60 2 38 5.6E-14 T 28-03-2018 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Pfam PF02151 UvrB/uvrC motif 422 454 1.3E-8 T 28-03-2018 IPR001943 UVR domain GO:0005515 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Gene3D G3DSA:3.40.50.300 497 719 2.7E-53 T 28-03-2018 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 SMART SM00382 542 721 1.6E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 SMART SM00382 205 349 4.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 546 564 1.1E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 591 609 1.1E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 620 638 1.1E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 653 667 1.1E-38 T 28-03-2018 IPR001270 ClpA/B family GO:0005524 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Gene3D G3DSA:3.40.50.300 198 347 3.7E-19 T 28-03-2018 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Gene3D G3DSA:1.10.8.60 349 492 3.1E-42 T 28-03-2018 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 SMART SM01086 720 811 3.6E-33 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Gene3D G3DSA:1.10.8.60 720 825 1.6E-22 T 28-03-2018 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 300 312 - T 28-03-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Gene3D G3DSA:1.10.1780.10 81 197 7.9E-29 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Pfam PF07724 AAA domain (Cdc48 subfamily) 541 714 8.3E-51 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 SUPERFAMILY SSF81923 3 145 1.67E-32 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 142 3.9E-17 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 16 68 6.5E-18 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 720 798 8.8E-25 T 28-03-2018 IPR019489 Clp ATPase, C-terminal CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 SUPERFAMILY SSF52540 168 489 5.41E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Gene3D G3DSA:1.10.1780.10 1 80 1.6E-28 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 210 339 2.6E-13 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS01720 ede3665ff47cf0415f9a7b6af7051060 852 SUPERFAMILY SSF52540 491 804 2.46E-76 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27145 095b105ecf93f1ff0fbac0afd975365a 209 Hamap MF_00527 Putative 3-methyladenine DNA glycosylase. 10 199 30.282 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CNX65_RS27145 095b105ecf93f1ff0fbac0afd975365a 209 Gene3D G3DSA:3.10.300.10 8 206 8.4E-68 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CNX65_RS27145 095b105ecf93f1ff0fbac0afd975365a 209 TIGRFAM TIGR00567 3mg: DNA-3-methyladenine glycosylase 14 197 1.3E-57 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CNX65_RS27145 095b105ecf93f1ff0fbac0afd975365a 209 SUPERFAMILY SSF50486 11 204 4.79E-59 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CNX65_RS27145 095b105ecf93f1ff0fbac0afd975365a 209 Pfam PF02245 Methylpurine-DNA glycosylase (MPG) 19 193 1.7E-63 T 28-03-2018 IPR003180 Methylpurine-DNA glycosylase (MPG) GO:0003677|GO:0003905|GO:0006284 Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 CNX65_RS15440 86c8b5a065ec148640cc9fd412311974 340 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 317 2.7E-41 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS15440 86c8b5a065ec148640cc9fd412311974 340 Gene3D G3DSA:1.10.3470.10 20 330 3.9E-30 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 SMART SM00418 35 113 8.3E-29 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 Pfam PF01022 Bacterial regulatory protein, arsR family 43 86 4.5E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 SUPERFAMILY SSF46785 25 108 4.8E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 Gene3D G3DSA:1.10.10.10 12 130 3.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 5.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 5.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 5.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS06290 4951abe713e8bbd1c3b60dff4677c08d 133 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 5.3E-14 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS31085 4ae4de97cc75a7523b929720710d3c59 225 Gene3D G3DSA:3.40.50.2300 2 121 2.9E-38 T 28-03-2018 CNX65_RS31085 4ae4de97cc75a7523b929720710d3c59 225 Pfam PF00072 Response regulator receiver domain 5 114 1.2E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS31085 4ae4de97cc75a7523b929720710d3c59 225 SUPERFAMILY SSF52172 3 179 1.71E-45 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS31085 4ae4de97cc75a7523b929720710d3c59 225 Gene3D G3DSA:1.10.10.10 122 225 2.9E-35 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31085 4ae4de97cc75a7523b929720710d3c59 225 SMART SM00862 146 222 1.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS31085 4ae4de97cc75a7523b929720710d3c59 225 SMART SM00448 3 113 7.2E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS31085 4ae4de97cc75a7523b929720710d3c59 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 221 4.1E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS32795 c86fcfa38a02bd81e1e0aa9efc4c90e9 292 TIGRFAM TIGR01207 rmlA: glucose-1-phosphate thymidylyltransferase 2 286 1.1E-138 T 28-03-2018 IPR005907 Glucose-1-phosphate thymidylyltransferase, short form GO:0008879|GO:0045226 KEGG: 00521+2.7.7.24|KEGG: 00523+2.7.7.24|KEGG: 00525+2.7.7.24|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 CNX65_RS32795 c86fcfa38a02bd81e1e0aa9efc4c90e9 292 Pfam PF00483 Nucleotidyl transferase 2 237 6.9E-61 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CNX65_RS32795 c86fcfa38a02bd81e1e0aa9efc4c90e9 292 Gene3D G3DSA:3.90.550.10 1 290 1.3E-65 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS32795 c86fcfa38a02bd81e1e0aa9efc4c90e9 292 SUPERFAMILY SSF53448 2 285 1.04E-82 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS27995 245bd56b99118e10294c78fa19029af3 240 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 105 147 5.3E-6 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS27995 245bd56b99118e10294c78fa19029af3 240 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 174 223 1.1E-12 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS27995 245bd56b99118e10294c78fa19029af3 240 SUPERFAMILY SSF81923 88 219 3.73E-19 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS27995 245bd56b99118e10294c78fa19029af3 240 Gene3D G3DSA:1.10.1780.10 81 162 2.9E-13 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS27995 245bd56b99118e10294c78fa19029af3 240 Gene3D G3DSA:1.10.1780.10 163 239 8.5E-19 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 SMART SM00895 93 215 9.9E-22 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 Gene3D G3DSA:1.20.120.530 71 224 1.5E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 SUPERFAMILY SSF48008 89 220 1.33E-28 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 Gene3D G3DSA:1.10.10.10 2 68 4.4E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 SUPERFAMILY SSF46785 9 70 7.26E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 Pfam PF07729 FCD domain 93 214 1.9E-25 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 66 3.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS02050 748a6208fb280df088fa3930f454d242 224 SMART SM00345 7 66 2.7E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS01215 e5fd6c4a4613298a186359d00789dbee 207 SUPERFAMILY SSF55811 22 179 4.74E-26 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS01215 e5fd6c4a4613298a186359d00789dbee 207 Pfam PF00293 NUDIX domain 27 144 1.1E-12 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS01215 e5fd6c4a4613298a186359d00789dbee 207 Gene3D G3DSA:3.90.79.10 4 187 3.2E-32 T 28-03-2018 CNX65_RS06455 0b62fb18f6011d94bf5bf99303180823 274 Pfam PF04672 S-adenosyl methyltransferase 9 273 1.9E-66 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS06455 0b62fb18f6011d94bf5bf99303180823 274 Gene3D G3DSA:3.40.50.150 1 274 1.5E-41 T 28-03-2018 CNX65_RS06455 0b62fb18f6011d94bf5bf99303180823 274 PIRSF PIRSF017393 1 274 1.0E-69 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS06455 0b62fb18f6011d94bf5bf99303180823 274 SUPERFAMILY SSF53335 17 250 2.21E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 SUPERFAMILY SSF48452 589 790 4.8E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 Gene3D G3DSA:1.25.40.10 431 570 0.049 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 Gene3D G3DSA:1.25.40.10 12 291 0.061 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 Gene3D G3DSA:1.25.40.10 571 705 1.1E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 SMART SM00028 708 741 0.027 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 SMART SM00028 767 800 220.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 SMART SM00028 667 700 68.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS27230 1d85a8751615e1a7ffe550100efffd98 943 Gene3D G3DSA:1.25.40.10 706 939 2.0E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 292 446 1.0E-27 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 SUPERFAMILY SSF55785 157 283 9.5E-25 T 28-03-2018 IPR000014 PAS domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 Gene3D G3DSA:3.20.20.450 459 700 1.3E-36 T 28-03-2018 IPR001633 EAL domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 Gene3D G3DSA:3.30.450.20 138 301 7.7E-31 T 28-03-2018 CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 SMART SM00267 285 452 1.1E-38 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 Pfam PF00990 Diguanylate cyclase, GGDEF domain 297 446 7.7E-28 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 168 292 1.0E-17 T 28-03-2018 IPR000014 PAS domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 SUPERFAMILY SSF141868 469 696 1.57E-23 T 28-03-2018 IPR001633 EAL domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 Gene3D G3DSA:3.30.70.270 302 458 5.1E-39 T 28-03-2018 CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 Pfam PF08448 PAS fold 176 286 2.1E-14 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 SMART SM00091 170 236 3.7E-9 T 28-03-2018 IPR000014 PAS domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 Pfam PF00563 EAL domain 468 694 1.5E-26 T 28-03-2018 IPR001633 EAL domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 SMART SM00052 462 699 8.9E-9 T 28-03-2018 IPR001633 EAL domain CNX65_RS06450 db3c85edfcbfb4b618f8986bc3415537 700 SUPERFAMILY SSF55073 301 453 4.47E-30 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS07360 4bf9d2763f795ab5b88b2932297af7f4 260 Gene3D G3DSA:1.10.10.10 3 74 3.5E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07360 4bf9d2763f795ab5b88b2932297af7f4 260 SUPERFAMILY SSF55781 80 255 3.73E-44 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS07360 4bf9d2763f795ab5b88b2932297af7f4 260 SUPERFAMILY SSF46785 13 86 2.15E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07360 4bf9d2763f795ab5b88b2932297af7f4 260 Gene3D G3DSA:3.30.450.40 78 257 2.9E-45 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS07360 4bf9d2763f795ab5b88b2932297af7f4 260 Pfam PF01614 Bacterial transcriptional regulator 131 252 2.3E-25 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS07360 4bf9d2763f795ab5b88b2932297af7f4 260 Pfam PF09339 IclR helix-turn-helix domain 15 65 5.6E-15 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS07360 4bf9d2763f795ab5b88b2932297af7f4 260 SMART SM00346 13 103 3.6E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 PRINTS PR01249 Ribosomal protein L31 signature 32 47 2.8E-21 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 PRINTS PR01249 Ribosomal protein L31 signature 47 65 2.8E-21 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.8E-21 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 Pfam PF01197 Ribosomal protein L31 2 66 9.5E-31 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 SUPERFAMILY SSF143800 1 66 4.71E-25 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 TIGRFAM TIGR00105 L31: ribosomal protein bL31 2 67 9.5E-32 T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 69 29.114 T 28-03-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30275 c1ea67e6a7b43e03675a0d5d66bbaaaa 70 ProSitePatterns PS01143 Ribosomal protein L31 signature. 36 57 - T 28-03-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS14090 e51c5bafa9397ab0f842278467b8b7bb 284 Gene3D G3DSA:1.10.260.40 10 93 3.8E-17 T 28-03-2018 CNX65_RS14090 e51c5bafa9397ab0f842278467b8b7bb 284 Pfam PF13560 Helix-turn-helix domain 12 91 3.6E-19 T 28-03-2018 CNX65_RS14090 e51c5bafa9397ab0f842278467b8b7bb 284 SMART SM00530 16 88 2.6E-9 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS14090 e51c5bafa9397ab0f842278467b8b7bb 284 SUPERFAMILY SSF47413 36 87 1.55E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 Gene3D G3DSA:3.20.20.300 17 381 3.6E-99 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 SMART SM01217 672 741 7.1E-23 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 Gene3D G3DSA:3.40.50.1700 385 635 2.4E-66 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 400 635 5.8E-48 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 Gene3D G3DSA:2.60.40.10 636 753 2.7E-25 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 Pfam PF14310 Fibronectin type III-like domain 672 741 5.2E-17 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 PRINTS PR00133 Glycosyl hydrolase family 3 signature 108 124 7.7E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 PRINTS PR00133 Glycosyl hydrolase family 3 signature 131 150 7.7E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 PRINTS PR00133 Glycosyl hydrolase family 3 signature 279 297 7.7E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 PRINTS PR00133 Glycosyl hydrolase family 3 signature 177 193 7.7E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 PRINTS PR00133 Glycosyl hydrolase family 3 signature 208 224 7.7E-17 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 SUPERFAMILY SSF51445 11 399 1.05E-90 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 SUPERFAMILY SSF52279 400 638 9.02E-46 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS09895 2f29f409e2083ee933e6411b00adf746 803 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 31 358 1.9E-67 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 Gene3D G3DSA:1.10.260.40 31 70 2.0E-15 T 28-03-2018 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 Gene3D G3DSA:3.40.50.2300 178 343 1.0E-52 T 28-03-2018 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 59 8.1E-12 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 Gene3D G3DSA:1.10.10.60 11 30 0.0042 T 28-03-2018 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 SMART SM00354 14 81 1.1E-9 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 SUPERFAMILY SSF47413 15 63 2.88E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 Gene3D G3DSA:3.40.50.2300 71 177 2.1E-20 T 28-03-2018 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 Pfam PF13377 Periplasmic binding protein-like domain 179 340 1.0E-37 T 28-03-2018 CNX65_RS09900 bc95c53b1e82da0372ca2c630f973b6b 345 SUPERFAMILY SSF53822 72 343 3.81E-76 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS29270 e654772778cc84b2df2a7a9fc88a9c3a 142 SUPERFAMILY SSF46785 10 138 1.61E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29270 e654772778cc84b2df2a7a9fc88a9c3a 142 Gene3D G3DSA:1.10.287.100 105 141 1.4E-7 T 28-03-2018 CNX65_RS29270 e654772778cc84b2df2a7a9fc88a9c3a 142 Gene3D G3DSA:1.10.10.10 20 104 4.5E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29270 e654772778cc84b2df2a7a9fc88a9c3a 142 Pfam PF01047 MarR family 33 90 6.9E-16 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS29270 e654772778cc84b2df2a7a9fc88a9c3a 142 SMART SM00347 26 126 6.7E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 1.2E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 Gene3D G3DSA:3.40.190.10 172 256 6.5E-8 T 28-03-2018 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 SUPERFAMILY SSF46785 1 85 3.08E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 Gene3D G3DSA:1.10.10.10 1 83 1.1E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 SUPERFAMILY SSF53850 102 279 1.33E-21 T 28-03-2018 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 Gene3D G3DSA:3.40.190.10 84 171 6.6E-17 T 28-03-2018 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 8.5E-21 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS24170 b18c5e26501c0b8ad8406db48307c5e2 280 Pfam PF03466 LysR substrate binding domain 102 278 6.9E-22 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 SUPERFAMILY SSF52518 431 847 1.47E-87 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 133 365 9.8E-53 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Gene3D G3DSA:3.40.50.970 476 837 2.4E-94 T 28-03-2018 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Pfam PF16078 2-oxoglutarate dehydrogenase N-terminus 9 43 1.8E-12 T 28-03-2018 IPR032106 2-oxoglutarate dehydrogenase E1 component, N-terminal domain KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Pfam PF16870 2-oxoglutarate dehydrogenase C-terminal 1100 1241 1.9E-46 T 28-03-2018 IPR031717 Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 TIGRFAM TIGR00239 2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component 399 1240 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Gene3D G3DSA:3.30.559.10 115 366 3.6E-52 T 28-03-2018 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Gene3D G3DSA:1.10.287.1150 393 475 1.0E-25 T 28-03-2018 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 SUPERFAMILY SSF52777 121 365 4.89E-54 T 28-03-2018 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Pfam PF00676 Dehydrogenase E1 component 517 841 2.0E-59 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Gene3D G3DSA:3.40.50.970 898 1109 8.1E-53 T 28-03-2018 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 SUPERFAMILY SSF52518 889 1102 1.37E-45 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 PIRSF PIRSF000157 2 1242 0.0 T 28-03-2018 IPR011603 2-oxoglutarate dehydrogenase E1 component GO:0004591|GO:0006099|GO:0030976|GO:0055114 KEGG: 00020+1.2.4.2|KEGG: 00310+1.2.4.2|KEGG: 00380+1.2.4.2|MetaCyc: PWY-5084 CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 SMART SM00861 902 1095 9.7E-50 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS30785 761df9ba9b5f59e4a446f629a5ef8932 1242 Pfam PF02779 Transketolase, pyrimidine binding domain 902 1094 1.6E-54 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS00645 091cdc0d9e3ef08ad80500694160d6d9 299 SUPERFAMILY SSF53448 3 247 1.69E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS00645 091cdc0d9e3ef08ad80500694160d6d9 299 Gene3D G3DSA:3.90.550.10 2 280 3.0E-31 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS00645 091cdc0d9e3ef08ad80500694160d6d9 299 Pfam PF00535 Glycosyl transferase family 2 6 115 1.5E-22 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS06465 effddd9038c9a401b14b78bd93dbbd66 121 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 16 109 3.8E-17 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CNX65_RS06465 effddd9038c9a401b14b78bd93dbbd66 121 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 14 114 16.296 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CNX65_RS00415 1b36ed280ac605af3c6c9e39340b1cb8 187 SUPERFAMILY SSF47240 13 159 5.0E-46 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS00415 1b36ed280ac605af3c6c9e39340b1cb8 187 Pfam PF00210 Ferritin-like domain 18 153 4.6E-36 T 28-03-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 CNX65_RS00415 1b36ed280ac605af3c6c9e39340b1cb8 187 Gene3D G3DSA:1.20.1260.10 7 187 4.8E-46 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS15785 d9341edf44f232656a6b20539fc6f886 289 Pfam PF05368 NmrA-like family 5 222 1.5E-19 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CNX65_RS15785 d9341edf44f232656a6b20539fc6f886 289 Gene3D G3DSA:3.40.50.720 3 75 1.6E-12 T 28-03-2018 CNX65_RS15785 d9341edf44f232656a6b20539fc6f886 289 SUPERFAMILY SSF51735 5 249 3.01E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15785 d9341edf44f232656a6b20539fc6f886 289 Gene3D G3DSA:3.40.50.720 101 285 4.7E-4 T 28-03-2018 CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 Pfam PF01580 FtsK/SpoIIIE family 467 667 1.4E-62 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 SUPERFAMILY SSF52540 441 739 3.72E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 Pfam PF09397 Ftsk gamma domain 772 829 2.0E-21 T 28-03-2018 IPR018541 FtsK gamma domain CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 Gene3D G3DSA:1.10.10.10 769 823 1.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 Gene3D G3DSA:3.40.50.300 377 709 7.5E-45 T 28-03-2018 CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 SUPERFAMILY SSF46785 769 833 1.13E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 Pfam PF13491 4TM region of DNA translocase FtsK/SpoIIIE 111 232 6.0E-7 T 28-03-2018 IPR025199 DNA translocase FtsK, 4TM region CNX65_RS28445 99a0e3e99f7a720ab41ba5f8160242f0 853 SMART SM00843 768 832 1.0E-28 T 28-03-2018 IPR018541 FtsK gamma domain CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 ProSitePatterns PS00211 ABC transporters family signature. 160 174 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 Gene3D G3DSA:3.40.50.300 300 540 2.3E-49 T 28-03-2018 CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 Pfam PF00005 ABC transporter 17 197 2.3E-20 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 Pfam PF00005 ABC transporter 353 481 7.0E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 SMART SM00382 26 242 2.5E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 SMART SM00382 360 527 8.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 Pfam PF12848 ABC transporter 239 314 8.3E-9 T 28-03-2018 IPR032781 ABC-transporter extension domain CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 SUPERFAMILY SSF52540 3 239 1.72E-39 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 Gene3D G3DSA:3.40.50.300 1 299 1.2E-46 T 28-03-2018 CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 SUPERFAMILY SSF52540 316 527 1.5E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25515 36dd3627ad7f65b6d35b29c474209221 542 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS17060 876cf35b847f14bec59c39631495559e 598 Pfam PF00005 ABC transporter 364 517 2.1E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS17060 876cf35b847f14bec59c39631495559e 598 SUPERFAMILY SSF90123 20 310 3.45E-6 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS17060 876cf35b847f14bec59c39631495559e 598 Gene3D G3DSA:3.40.50.300 343 590 5.3E-53 T 28-03-2018 CNX65_RS17060 876cf35b847f14bec59c39631495559e 598 ProSitePatterns PS00211 ABC transporters family signature. 488 502 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS17060 876cf35b847f14bec59c39631495559e 598 SUPERFAMILY SSF52540 337 593 5.22E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17060 876cf35b847f14bec59c39631495559e 598 Gene3D G3DSA:1.20.1560.10 11 326 4.2E-4 T 28-03-2018 CNX65_RS17060 876cf35b847f14bec59c39631495559e 598 SMART SM00382 372 569 3.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 SMART SM00419 189 236 1.4E-4 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 SUPERFAMILY SSF51206 38 144 1.31E-19 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 Pfam PF13545 Crp-like helix-turn-helix domain 173 242 4.9E-10 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 SUPERFAMILY SSF46785 171 244 1.79E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 Pfam PF00027 Cyclic nucleotide-binding domain 56 136 5.5E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 Gene3D G3DSA:2.60.120.10 55 162 5.0E-15 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 Gene3D G3DSA:1.10.10.10 169 246 3.1E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18620 5e6fc4d2c1505a649a0330912585bd10 246 SMART SM00100 35 154 1.8E-9 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS19955 d3c0da0de994199aba9398c6a430cee6 466 Pfam PF13646 HEAT repeats 269 338 1.9E-6 T 28-03-2018 CNX65_RS19955 d3c0da0de994199aba9398c6a430cee6 466 SUPERFAMILY SSF48371 242 339 1.64E-14 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19955 d3c0da0de994199aba9398c6a430cee6 466 SUPERFAMILY SSF48371 178 194 1.64E-14 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19955 d3c0da0de994199aba9398c6a430cee6 466 SUPERFAMILY SSF48371 31 127 1.64E-14 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19955 d3c0da0de994199aba9398c6a430cee6 466 Gene3D G3DSA:1.25.10.10 21 462 5.9E-17 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 PIRSF PIRSF000478 2 423 2.3E-149 T 28-03-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 SUPERFAMILY SSF52418 74 316 3.53E-81 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 111 126 - T 28-03-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 Gene3D G3DSA:1.20.970.10 2 69 1.8E-22 T 28-03-2018 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 6 407 2.7E-164 T 28-03-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 Gene3D G3DSA:3.40.1030.10 70 324 1.9E-82 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 Gene3D G3DSA:3.90.1170.30 325 411 4.5E-26 T 28-03-2018 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 SUPERFAMILY SSF47648 4 71 5.49E-20 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 Pfam PF00591 Glycosyl transferase family, a/b domain 78 285 2.4E-33 T 28-03-2018 IPR000312 Glycosyl transferase, family 3 GO:0008152|GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 Pfam PF02885 Glycosyl transferase family, helical bundle domain 6 68 4.8E-18 T 28-03-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 SMART SM00941 334 408 6.3E-29 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 335 406 2.7E-20 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS31635 d28ecc555a4f764ba97b1e724d341a6b 424 SUPERFAMILY SSF54680 321 422 4.05E-24 T 28-03-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 Pfam PF00069 Protein kinase domain 236 409 3.6E-9 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 Gene3D G3DSA:1.50.10.20 512 811 3.7E-10 T 28-03-2018 CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 SMART SM01260 518 836 8.2E-6 T 28-03-2018 IPR007822 Lanthionine synthetase C-like CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 SUPERFAMILY SSF158745 716 822 3.4E-5 T 28-03-2018 CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 SMART SM00220 225 517 5.0E-4 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 Gene3D G3DSA:1.10.510.10 221 453 2.0E-19 T 28-03-2018 CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 SUPERFAMILY SSF56112 225 419 5.33E-21 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 SUPERFAMILY SSF158745 511 696 1.01E-15 T 28-03-2018 CNX65_RS06530 7719d23b16f3ff5c1bc9dd40b9d7e6d3 849 Gene3D G3DSA:3.30.2430.10 30 180 2.3E-28 T 28-03-2018 CNX65_RS13400 94a904f55409b30ff2f5ed00912044f8 165 Gene3D G3DSA:3.40.1000.10 9 157 5.3E-14 T 28-03-2018 CNX65_RS28490 b930aff16db460d247d6b4dea219e13d 297 Pfam PF13349 Putative adhesin 113 266 1.6E-7 T 28-03-2018 IPR025164 Putative adhesin CNX65_RS30955 ae0ae47731bc8a36920259fb4bef925e 263 Pfam PF04672 S-adenosyl methyltransferase 11 260 8.4E-79 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS30955 ae0ae47731bc8a36920259fb4bef925e 263 Gene3D G3DSA:3.40.50.150 1 262 4.6E-38 T 28-03-2018 CNX65_RS30955 ae0ae47731bc8a36920259fb4bef925e 263 PIRSF PIRSF017393 2 263 6.1E-84 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS30955 ae0ae47731bc8a36920259fb4bef925e 263 SUPERFAMILY SSF53335 14 246 6.72E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS32765 3fc7f7e463900a10d8e034de257f2659 208 Gene3D G3DSA:3.40.50.300 25 51 0.0013 T 28-03-2018 CNX65_RS32765 3fc7f7e463900a10d8e034de257f2659 208 SUPERFAMILY SSF52540 34 158 2.33E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS32765 3fc7f7e463900a10d8e034de257f2659 208 PIRSF PIRSF037081 40 205 6.1E-18 T 28-03-2018 IPR017101 P-loop ATP/GTP binding protein, All4644, predicted CNX65_RS32765 3fc7f7e463900a10d8e034de257f2659 208 Pfam PF13671 AAA domain 44 180 4.4E-18 T 28-03-2018 CNX65_RS32765 3fc7f7e463900a10d8e034de257f2659 208 Gene3D G3DSA:3.40.50.300 52 205 4.5E-13 T 28-03-2018 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 SMART SM00881 4 104 8.7E-31 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 292 39.523 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 Pfam PF00549 CoA-ligase 158 275 1.6E-14 T 28-03-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 SUPERFAMILY SSF51735 1 128 7.19E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 291 4.1E-125 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 Gene3D G3DSA:3.40.50.720 1 125 3.2E-40 T 28-03-2018 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 240 253 - T 28-03-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 Pfam PF02629 CoA binding domain 6 103 1.1E-25 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 Gene3D G3DSA:3.40.50.261 126 295 1.2E-47 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 158 185 - T 28-03-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 PRINTS PR01798 Succinyl-CoA synthase signature 181 199 2.3E-34 T 28-03-2018 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 PRINTS PR01798 Succinyl-CoA synthase signature 86 103 2.3E-34 T 28-03-2018 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 PRINTS PR01798 Succinyl-CoA synthase signature 212 225 2.3E-34 T 28-03-2018 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 PRINTS PR01798 Succinyl-CoA synthase signature 244 261 2.3E-34 T 28-03-2018 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 SUPERFAMILY SSF52210 129 290 6.54E-45 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS31930 ab4575fa4893efad719228ddea37b27e 296 PIRSF PIRSF001553 1 295 4.9E-115 T 28-03-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824|GO:0008152 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 SMART SM00387 390 490 7.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 Pfam PF12282 Signal transduction histidine kinase 4 146 8.7E-54 T 28-03-2018 IPR022066 Signal transduction histidine kinase CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 SUPERFAMILY SSF55874 353 488 6.02E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 Gene3D G3DSA:3.30.565.10 291 489 1.5E-22 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 Pfam PF08448 PAS fold 173 282 1.7E-10 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 Gene3D G3DSA:3.30.450.20 171 290 4.3E-11 T 28-03-2018 CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 SUPERFAMILY SSF55785 175 287 5.58E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 394 489 1.9E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30980 f55d44bfbce627d518ce38c570f85fba 492 Pfam PF07568 Histidine kinase 296 366 3.5E-24 T 28-03-2018 IPR011495 Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain CNX65_RS34240 b02f3fdd9c40f36ab10708a6a9a68409 306 PRINTS PR00990 Ribokinase signature 6 27 3.8E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS34240 b02f3fdd9c40f36ab10708a6a9a68409 306 PRINTS PR00990 Ribokinase signature 33 52 3.8E-5 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS34240 b02f3fdd9c40f36ab10708a6a9a68409 306 SUPERFAMILY SSF53613 4 291 2.96E-44 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS34240 b02f3fdd9c40f36ab10708a6a9a68409 306 Pfam PF00294 pfkB family carbohydrate kinase 229 290 1.1E-9 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS34240 b02f3fdd9c40f36ab10708a6a9a68409 306 Pfam PF00294 pfkB family carbohydrate kinase 4 182 6.2E-16 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS34240 b02f3fdd9c40f36ab10708a6a9a68409 306 Gene3D G3DSA:3.40.1190.20 1 304 1.5E-50 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS34240 b02f3fdd9c40f36ab10708a6a9a68409 306 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 251 264 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 427 3.1E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 Pfam PF13188 PAS domain 227 289 3.5E-6 T 28-03-2018 IPR000014 PAS domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 Gene3D G3DSA:1.10.287.130 370 422 5.6E-13 T 28-03-2018 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SMART SM00387 474 586 1.7E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SUPERFAMILY SSF55874 418 584 5.59E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SUPERFAMILY SSF55785 213 342 5.41E-10 T 28-03-2018 IPR000014 PAS domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 546 564 3.7E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 PRINTS PR00344 Bacterial sensor protein C-terminal signature 570 583 3.7E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 Gene3D G3DSA:3.30.565.10 423 586 2.2E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 Gene3D G3DSA:3.30.450.20 224 369 8.2E-20 T 28-03-2018 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 Gene3D G3DSA:3.30.450.20 66 223 1.4E-8 T 28-03-2018 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SMART SM00388 364 428 1.4E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SUPERFAMILY SSF47384 347 428 2.75E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 512 585 2.8E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SMART SM00091 99 166 130.0 T 28-03-2018 IPR000014 PAS domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SMART SM00091 227 296 0.0064 T 28-03-2018 IPR000014 PAS domain CNX65_RS12495 a6b24719e874282fdc94ecd6521d7980 597 SUPERFAMILY SSF55785 104 217 4.0E-6 T 28-03-2018 IPR000014 PAS domain CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 Gene3D G3DSA:1.10.10.10 155 243 2.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 Gene3D G3DSA:3.40.50.2300 39 154 8.4E-4 T 28-03-2018 CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 SMART SM00421 180 237 1.4E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 213 225 3.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 197 3.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 197 213 3.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 Pfam PF00196 Bacterial regulatory proteins, luxR family 183 237 2.9E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS24660 da9c0e3681e282b1a10b1758986e4948 243 SUPERFAMILY SSF46894 177 243 3.03E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:3.40.366.10 535 667 2.2E-37 T 28-03-2018 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF08990 Erythronolide synthase docking 2 27 1.1E-7 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:1.10.1200.10 1409 1503 4.6E-16 T 28-03-2018 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 34 280 7.5E-85 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF07993 Male sterility protein 1530 1760 4.5E-59 T 28-03-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF55048 660 719 4.05E-11 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF08659 KR domain 1194 1347 1.4E-42 T 28-03-2018 IPR013968 Polyketide synthase, ketoreductase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:3.40.47.10 296 456 2.9E-59 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF51735 1058 1184 2.56E-8 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF00698 Acyl transferase domain 538 804 1.1E-52 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SMART SM00825 Beta-ketoacyl synthase 36 454 2.3E-191 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:3.40.366.10 714 815 1.7E-17 T 28-03-2018 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:3.40.47.10 26 292 1.6E-78 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SMART SM00826 875 1012 4.3E-7 T 28-03-2018 IPR020807 Polyketide synthase, dehydratase domain Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF47336 1426 1493 5.37E-14 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF51735 1191 1399 3.53E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:3.40.50.720 1522 1860 7.2E-38 T 28-03-2018 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 415 489 1.5E-11 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF52151 722 806 3.92E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF52151 535 661 3.92E-53 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 1194 1349 6.9E-33 T 28-03-2018 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 288 403 7.8E-41 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 TIGRFAM TIGR01746 Thioester-redct: thioester reductase domain 1528 1867 1.3E-88 T 28-03-2018 IPR010080 Thioester reductase-like domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 539 817 1.8E-83 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF53901 29 401 1.24E-92 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:3.30.70.250 668 713 7.4E-16 T 28-03-2018 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SUPERFAMILY SSF51735 1529 1805 5.6E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Gene3D G3DSA:3.40.50.720 1184 1394 9.3E-42 T 28-03-2018 CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 Pfam PF00550 Phosphopantetheine attachment site 1429 1490 1.0E-9 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23010 ae837688f134b65aa92d5bd45ab48b18 1874 SMART SM00823 Phosphopantetheine attachment site 1426 1494 1.3E-22 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS09590 53483164a1c7bf0de12d3f4aa860c363 341 Gene3D G3DSA:3.30.200.20 28 120 1.6E-17 T 28-03-2018 CNX65_RS09590 53483164a1c7bf0de12d3f4aa860c363 341 Pfam PF00069 Protein kinase domain 45 278 2.0E-38 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS09590 53483164a1c7bf0de12d3f4aa860c363 341 SUPERFAMILY SSF56112 32 317 2.46E-59 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS09590 53483164a1c7bf0de12d3f4aa860c363 341 Gene3D G3DSA:1.10.510.10 121 287 1.1E-39 T 28-03-2018 CNX65_RS19800 fadd25b000614c8c09caff21f021cde0 365 Gene3D G3DSA:2.160.20.10 99 356 9.5E-57 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS19800 fadd25b000614c8c09caff21f021cde0 365 SMART SM00656 77 286 1.2E-17 T 28-03-2018 IPR002022 Pectate lyase CNX65_RS19800 fadd25b000614c8c09caff21f021cde0 365 SUPERFAMILY SSF51126 34 356 1.05E-72 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS19800 fadd25b000614c8c09caff21f021cde0 365 Pfam PF00544 Pectate lyase 80 280 1.7E-33 T 28-03-2018 IPR002022 Pectate lyase CNX65_RS19800 fadd25b000614c8c09caff21f021cde0 365 Gene3D G3DSA:2.160.20.10 15 98 5.4E-11 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS11145 bc3432ef6649f3cbac7f0023b0be90c8 257 ProDom PD040491 SCO1799 RV1486C/MT1533 MB1522C CGL1536 ML1804 MAV321 2 242 7.0E-15 T 28-03-2018 CNX65_RS25715 8d61b7ea5c568c50616e3fe81e9fbc29 146 Gene3D G3DSA:1.10.10.10 11 145 4.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25715 8d61b7ea5c568c50616e3fe81e9fbc29 146 Pfam PF05331 Protein of unknown function (DUF742) 33 146 1.2E-33 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CNX65_RS08690 b4fb43731e005d65ca3270f46b09d968 319 Gene3D G3DSA:2.140.10.30 24 318 5.8E-9 T 28-03-2018 CNX65_RS08690 b4fb43731e005d65ca3270f46b09d968 319 SUPERFAMILY SSF82171 83 309 2.24E-11 T 28-03-2018 CNX65_RS25815 a97192a548ad21acbbc184d7c4deed94 373 Pfam PF10128 Glucose-6-phosphate dehydrogenase subunit 52 297 2.1E-93 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CNX65_RS25815 a97192a548ad21acbbc184d7c4deed94 373 TIGRFAM TIGR00534 OpcA: glucose-6-phosphate dehydrogenase assembly protein OpcA 2 303 3.5E-83 T 28-03-2018 IPR004555 Glucose-6-phosphate dehydrogenase assembly protein OpcA CNX65_RS28980 29268bc5e50e58d7adec1506e40077ad 271 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 20 244 2.3E-5 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS28980 29268bc5e50e58d7adec1506e40077ad 271 Gene3D G3DSA:3.10.180.10 131 260 8.1E-10 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS28980 29268bc5e50e58d7adec1506e40077ad 271 SUPERFAMILY SSF54593 134 248 1.75E-9 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS28980 29268bc5e50e58d7adec1506e40077ad 271 SUPERFAMILY SSF54593 20 168 5.37E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS28980 29268bc5e50e58d7adec1506e40077ad 271 Gene3D G3DSA:3.10.180.10 19 121 5.8E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 Gene3D G3DSA:3.40.50.970 1 372 1.2E-73 T 28-03-2018 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 SUPERFAMILY SSF52518 370 583 1.03E-23 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 Pfam PF03894 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase 394 569 4.7E-77 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 Gene3D G3DSA:3.40.50.920 600 778 1.5E-64 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 PIRSF PIRSF017245 2 778 2.1E-297 T 28-03-2018 IPR005593 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase GO:0005975|GO:0016832 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 Gene3D G3DSA:3.40.50.970 375 594 6.4E-30 T 28-03-2018 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 Pfam PF09364 XFP N-terminal domain 10 379 2.0E-141 T 28-03-2018 IPR018970 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, N-terminal CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 SUPERFAMILY SSF52518 9 360 1.15E-54 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 ProSitePatterns PS60002 Phosphoketolase signature 1. 140 146 - T 28-03-2018 IPR019790 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, conserved site GO:0005975|GO:0016832 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 Pfam PF09363 XFP C-terminal domain 580 776 1.0E-70 T 28-03-2018 IPR018969 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, C-terminal GO:0005975|GO:0016832 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 SUPERFAMILY SSF52922 593 719 1.53E-5 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS16960 c613f23fe8372586e3c0e6b0a90a38b9 778 ProSitePatterns PS60003 Phosphoketolase signature 2. 153 171 - T 28-03-2018 IPR019789 Xylulose 5-phosphate/Fructose 6-phosphate phosphoketolase, thiamine diphosphate binding site GO:0005975|GO:0016832 CNX65_RS08900 73cadb737368abd01d88cb917d2b492b 335 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 110 329 3.7E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08900 73cadb737368abd01d88cb917d2b492b 335 Gene3D G3DSA:1.10.3720.10 96 330 1.9E-41 T 28-03-2018 CNX65_RS08900 73cadb737368abd01d88cb917d2b492b 335 Gene3D G3DSA:1.20.58.370 30 78 4.3E-6 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CNX65_RS08900 73cadb737368abd01d88cb917d2b492b 335 SUPERFAMILY SSF161098 89 318 5.49E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 Pfam PF00687 Ribosomal protein L1p/L10e family 30 219 5.5E-52 T 28-03-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 ProSitePatterns PS01199 Ribosomal protein L1 signature. 120 138 - T 28-03-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 2 226 1.2E-101 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 1 228 42.386 T 28-03-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 Gene3D G3DSA:3.30.190.20 15 129 1.2E-32 T 28-03-2018 CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 Gene3D G3DSA:3.30.190.20 130 223 1.2E-20 T 28-03-2018 CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 SUPERFAMILY SSF56808 5 226 1.26E-82 T 28-03-2018 IPR023674 Ribosomal protein L1-like CNX65_RS32575 c66f72663e889076b3fae970c1588165 238 PIRSF PIRSF002155 1 226 1.5E-74 T 28-03-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS20160 6601d8b88f2381588d01a0a57a6b7d0f 128 SUPERFAMILY SSF158682 4 126 1.83E-5 T 28-03-2018 CNX65_RS20160 6601d8b88f2381588d01a0a57a6b7d0f 128 Gene3D G3DSA:1.10.3680.10 1 127 6.9E-5 T 28-03-2018 IPR029024 TerB-like CNX65_RS29235 e37112c56ac3c3c4a3cbabfe1c3bf644 162 SUPERFAMILY SSF88946 4 85 1.26E-10 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29235 e37112c56ac3c3c4a3cbabfe1c3bf644 162 Pfam PF04542 Sigma-70 region 2 11 76 4.3E-7 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29235 e37112c56ac3c3c4a3cbabfe1c3bf644 162 Gene3D G3DSA:1.10.1740.10 2 78 9.2E-12 T 28-03-2018 CNX65_RS29235 e37112c56ac3c3c4a3cbabfe1c3bf644 162 SUPERFAMILY SSF88659 91 154 1.1E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29235 e37112c56ac3c3c4a3cbabfe1c3bf644 162 Pfam PF04545 Sigma-70, region 4 103 152 2.4E-9 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS29235 e37112c56ac3c3c4a3cbabfe1c3bf644 162 Gene3D G3DSA:1.10.10.10 79 161 2.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05170 76db36d29a7893b2d571f0cdb152444f 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 71 2.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS05170 76db36d29a7893b2d571f0cdb152444f 204 Pfam PF16859 Bacterial transcriptional repressor C-terminal 85 195 3.8E-33 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS05170 76db36d29a7893b2d571f0cdb152444f 204 SUPERFAMILY SSF46689 17 79 1.65E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS05170 76db36d29a7893b2d571f0cdb152444f 204 ProSitePatterns PS01081 TetR-type HTH domain signature. 39 70 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS05170 76db36d29a7893b2d571f0cdb152444f 204 SUPERFAMILY SSF48498 85 201 1.56E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS05170 76db36d29a7893b2d571f0cdb152444f 204 Gene3D G3DSA:1.10.10.60 5 69 2.1E-16 T 28-03-2018 CNX65_RS05170 76db36d29a7893b2d571f0cdb152444f 204 Gene3D G3DSA:1.10.357.10 70 201 5.9E-22 T 28-03-2018 CNX65_RS32495 268914a4f5ed3b56f101bc8ac934ed0d 182 SUPERFAMILY SSF56399 15 141 4.46E-8 T 28-03-2018 CNX65_RS32495 268914a4f5ed3b56f101bc8ac934ed0d 182 Gene3D G3DSA:3.90.210.10 11 178 4.4E-12 T 28-03-2018 CNX65_RS29425 674946eba06c9a67ce8c372706af64bd 155 Pfam PF05995 Cysteine dioxygenase type I 26 138 8.9E-19 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CNX65_RS29425 674946eba06c9a67ce8c372706af64bd 155 Gene3D G3DSA:2.60.120.10 6 145 1.3E-23 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS29425 674946eba06c9a67ce8c372706af64bd 155 SUPERFAMILY SSF51182 13 147 2.83E-27 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS01630 37cb6267c0887be7f58f2ef274733c3c 158 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 5 129 2.4E-31 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CNX65_RS01630 37cb6267c0887be7f58f2ef274733c3c 158 SUPERFAMILY SSF55083 3 149 2.09E-45 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CNX65_RS01630 37cb6267c0887be7f58f2ef274733c3c 158 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 84 95 - T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CNX65_RS01630 37cb6267c0887be7f58f2ef274733c3c 158 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 4 129 3.8E-37 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CNX65_RS01630 37cb6267c0887be7f58f2ef274733c3c 158 Gene3D G3DSA:3.30.70.560 1 156 5.0E-50 T 28-03-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 213 233 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.6E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 4.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 4.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 4.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 Gene3D G3DSA:3.40.50.720 45 250 5.0E-60 T 28-03-2018 CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 139 167 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 SUPERFAMILY SSF51735 3 248 1.06E-75 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 183 1.9E-5 T 28-03-2018 CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 Gene3D G3DSA:3.40.50.10090 1 44 2.2E-9 T 28-03-2018 CNX65_RS07970 59022c9c2644941ac51b5849b9d2f9a8 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 248 9.7E-59 T 28-03-2018 CNX65_RS19120 c172569ecb29693ec2cd552b3ecb7a2a 390 Pfam PF01594 AI-2E family transporter 37 348 2.1E-58 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CNX65_RS19120 c172569ecb29693ec2cd552b3ecb7a2a 390 Gene3D G3DSA:1.20.5.1230 90 308 8.7E-4 T 28-03-2018 CNX65_RS10415 07e24fac7418ba1747421b263a3ed492 207 Gene3D G3DSA:1.10.3480.10 2 182 5.5E-27 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CNX65_RS10415 07e24fac7418ba1747421b263a3ed492 207 SUPERFAMILY SSF89155 10 166 9.68E-30 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CNX65_RS10415 07e24fac7418ba1747421b263a3ed492 207 Pfam PF02613 Nitrate reductase delta subunit 41 156 1.0E-13 T 28-03-2018 IPR020945 DMSO/Nitrate reductase chaperone CNX65_RS10415 07e24fac7418ba1747421b263a3ed492 207 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 35 161 5.2E-35 T 28-03-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 PRINTS PR00364 Disease resistance protein signature 146 160 1.2E-5 T 28-03-2018 CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 PRINTS PR00364 Disease resistance protein signature 231 245 1.2E-5 T 28-03-2018 CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 PRINTS PR00364 Disease resistance protein signature 71 86 1.2E-5 T 28-03-2018 CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 SUPERFAMILY SSF52540 39 296 6.32E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 Gene3D G3DSA:1.25.40.10 517 790 3.0E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 Gene3D G3DSA:3.40.50.300 40 198 5.1E-14 T 28-03-2018 CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 SUPERFAMILY SSF48452 416 513 1.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS25560 441f7268ccf4eb389bd599d9872013d8 980 Gene3D G3DSA:1.25.40.10 362 481 3.9E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS18555 b6903b17134fae8f89b337c2affdae09 328 Gene3D G3DSA:3.40.190.10 136 300 1.4E-20 T 28-03-2018 CNX65_RS18555 b6903b17134fae8f89b337c2affdae09 328 SUPERFAMILY SSF53850 71 291 2.47E-17 T 28-03-2018 CNX65_RS18555 b6903b17134fae8f89b337c2affdae09 328 Pfam PF03401 Tripartite tricarboxylate transporter family receptor 66 325 1.7E-32 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CNX65_RS18555 b6903b17134fae8f89b337c2affdae09 328 PIRSF PIRSF017082 1 328 6.0E-90 T 28-03-2018 IPR005064 Bordetella uptake gene GO:0030288 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 140 226 1.3E-22 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 Gene3D G3DSA:1.10.8.50 142 291 9.5E-45 T 28-03-2018 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 SUPERFAMILY SSF46946 140 229 3.53E-26 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 280 1.3E-89 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 SMART SM01232 140 232 1.7E-39 T 28-03-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 2 119 1.5E-34 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 SUPERFAMILY SSF81624 2 149 5.49E-36 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 Pfam PF06827 Zinc finger found in FPG and IleRS 255 282 1.4E-7 T 28-03-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 281 39.737 T 28-03-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 Gene3D G3DSA:3.20.190.10 2 132 6.4E-45 T 28-03-2018 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 SUPERFAMILY SSF57716 232 281 2.2E-15 T 28-03-2018 CNX65_RS29275 767cde29005d6edac9033f385e951743 291 SMART SM00898 2 121 2.5E-49 T 28-03-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 CNX65_RS08115 f1f470f8d1816dcdb19424cc6d9bdc7e 239 Pfam PF12698 ABC-2 family transporter protein 44 227 2.9E-8 T 28-03-2018 CNX65_RS10745 1792b281013ad09d91937e31395ccfea 204 Gene3D G3DSA:3.40.50.880 1 204 8.2E-47 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS10745 1792b281013ad09d91937e31395ccfea 204 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 198 38.156 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10745 1792b281013ad09d91937e31395ccfea 204 SUPERFAMILY SSF52317 3 200 1.48E-46 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS10745 1792b281013ad09d91937e31395ccfea 204 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 4 196 1.2E-71 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10745 1792b281013ad09d91937e31395ccfea 204 PIRSF PIRSF005639 1 203 1.9E-71 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10745 1792b281013ad09d91937e31395ccfea 204 Pfam PF01174 SNO glutamine amidotransferase family 6 199 2.1E-56 T 28-03-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS10745 1792b281013ad09d91937e31395ccfea 204 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 28-03-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 CNX65_RS27980 fe74022954d238b52cbacbd133c4f240 257 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 2 257 47.259 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CNX65_RS27980 fe74022954d238b52cbacbd133c4f240 257 Pfam PF00977 Histidine biosynthesis protein 6 240 2.6E-84 T 28-03-2018 IPR006062 Histidine biosynthesis GO:0000105 CNX65_RS27980 fe74022954d238b52cbacbd133c4f240 257 Gene3D G3DSA:3.20.20.70 5 253 1.0E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS27980 fe74022954d238b52cbacbd133c4f240 257 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 3 257 6.1E-111 T 28-03-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 CNX65_RS27980 fe74022954d238b52cbacbd133c4f240 257 SUPERFAMILY SSF51366 4 257 2.2E-78 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS22155 659bf9ab513fb34a9ba91b1bfcf65d64 302 SUPERFAMILY SSF50129 2 145 3.35E-24 T 28-03-2018 IPR011032 GroES-like CNX65_RS22155 659bf9ab513fb34a9ba91b1bfcf65d64 302 SMART SM00829 12 299 2.4E-8 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS22155 659bf9ab513fb34a9ba91b1bfcf65d64 302 SUPERFAMILY SSF51735 107 270 3.62E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22155 659bf9ab513fb34a9ba91b1bfcf65d64 302 Gene3D G3DSA:3.90.180.10 1 140 1.0E-32 T 28-03-2018 CNX65_RS22155 659bf9ab513fb34a9ba91b1bfcf65d64 302 Pfam PF00107 Zinc-binding dehydrogenase 143 236 2.4E-10 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS22155 659bf9ab513fb34a9ba91b1bfcf65d64 302 Gene3D G3DSA:3.40.50.720 141 243 1.3E-14 T 28-03-2018 CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 1.6E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 1.6E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 165 1.6E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.6E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 1.6E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 184 1.6E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 237 6.6E-54 T 28-03-2018 CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 133 161 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 Gene3D G3DSA:3.40.50.720 2 41 8.4E-5 T 28-03-2018 CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 Gene3D G3DSA:3.40.50.720 42 237 1.9E-51 T 28-03-2018 CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 SUPERFAMILY SSF51735 6 237 3.75E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17435 57722c0837888d7ad18d8b5ee4a7454e 237 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 199 0.0039 T 28-03-2018 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 SUPERFAMILY SSF50249 614 742 1.37E-29 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Gene3D G3DSA:3.40.630.30 341 546 1.7E-4 T 28-03-2018 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 250 549 5.6E-100 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Gene3D G3DSA:2.40.50.140 614 741 3.6E-26 T 28-03-2018 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Pfam PF00152 tRNA synthetases class II (D, K and N) 750 1087 1.5E-72 T 28-03-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 PRINTS PR00982 Lysyl-tRNA synthetase signature 802 818 6.1E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 PRINTS PR00982 Lysyl-tRNA synthetase signature 974 990 6.1E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 PRINTS PR00982 Lysyl-tRNA synthetase signature 831 844 6.1E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 PRINTS PR00982 Lysyl-tRNA synthetase signature 786 796 6.1E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 PRINTS PR00982 Lysyl-tRNA synthetase signature 849 866 6.1E-31 T 28-03-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Pfam PF16995 Transmembrane region of lysyl-tRNA synthetase 11 231 9.0E-31 T 28-03-2018 IPR031553 Lysyl-tRNA synthetase, N-terminal transmembrane region KEGG: 00970+6.1.1.6 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Pfam PF01336 OB-fold nucleic acid binding domain 657 730 4.2E-11 T 28-03-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 SUPERFAMILY SSF55681 749 1089 2.99E-102 T 28-03-2018 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 617 1090 1.0E-142 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Gene3D G3DSA:3.30.930.10 743 1088 1.3E-86 T 28-03-2018 CNX65_RS04440 b045fb69124380311d67a5b12bf1665d 1094 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 620 1091 35.423 T 28-03-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 CNX65_RS00755 c06e3c3e38b2cf56870bb5757019bdd2 446 SUPERFAMILY SSF140459 46 151 3.14E-6 T 28-03-2018 CNX65_RS00755 c06e3c3e38b2cf56870bb5757019bdd2 446 Pfam PF00823 PPE family 60 150 4.8E-7 T 28-03-2018 IPR000030 PPE family CNX65_RS00755 c06e3c3e38b2cf56870bb5757019bdd2 446 Gene3D G3DSA:1.10.287.850 55 146 1.1E-8 T 28-03-2018 CNX65_RS17800 f50e0a4f25ec433afb75ce1d076af818 292 SUPERFAMILY SSF51735 3 272 3.25E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17800 f50e0a4f25ec433afb75ce1d076af818 292 Gene3D G3DSA:3.40.50.720 2 207 1.7E-26 T 28-03-2018 CNX65_RS17800 f50e0a4f25ec433afb75ce1d076af818 292 Pfam PF13460 NAD(P)H-binding 8 181 8.8E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12860 324429cac8745a13f7d74174de837988 158 Gene3D G3DSA:3.40.1490.10 28 156 3.8E-33 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CNX65_RS12860 324429cac8745a13f7d74174de837988 158 SUPERFAMILY SSF102462 28 157 1.05E-24 T 28-03-2018 IPR023476 Peptidyl-tRNA hydrolase II domain MetaCyc: PWY-6308 CNX65_RS12860 324429cac8745a13f7d74174de837988 158 Pfam PF09391 Protein of unknown function (DUF2000) 29 157 1.2E-37 T 28-03-2018 IPR018988 Protein of unknown function DUF2000 CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 Gene3D G3DSA:3.40.710.10 285 693 3.2E-72 T 28-03-2018 CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 Gene3D G3DSA:1.10.3810.10 49 260 2.0E-70 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 SUPERFAMILY SSF53955 46 258 2.14E-65 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 Pfam PF00905 Penicillin binding protein transpeptidase domain 359 617 5.0E-23 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 Pfam PF00912 Transglycosylase 57 244 1.2E-59 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 SUPERFAMILY SSF56601 292 491 8.28E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 SUPERFAMILY SSF56601 226 248 8.28E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS25450 357db20a107a08773f75a9b35bc48eca 693 SUPERFAMILY SSF56601 518 687 8.28E-71 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS06460 b60653f89ea1226b45a378a11d369760 145 SUPERFAMILY SSF46785 5 137 8.24E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06460 b60653f89ea1226b45a378a11d369760 145 SMART SM00347 25 125 2.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS06460 b60653f89ea1226b45a378a11d369760 145 Gene3D G3DSA:1.10.287.100 109 140 8.0E-6 T 28-03-2018 CNX65_RS06460 b60653f89ea1226b45a378a11d369760 145 Pfam PF12802 MarR family 31 88 4.9E-12 T 28-03-2018 CNX65_RS06460 b60653f89ea1226b45a378a11d369760 145 ProSitePatterns PS01117 MarR-type HTH domain signature. 64 98 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CNX65_RS06460 b60653f89ea1226b45a378a11d369760 145 Gene3D G3DSA:1.10.10.10 1 108 2.6E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 SUPERFAMILY SSF51735 2 212 5.04E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 185 3.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 3.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 210 3.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 3.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 147 166 3.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 Pfam PF00106 short chain dehydrogenase 5 190 3.4E-38 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS26585 f683ed4242460de1f1a8a4573d073c35 230 Gene3D G3DSA:3.40.50.720 3 221 3.6E-48 T 28-03-2018 CNX65_RS05100 cb129829c335501d2b9a5a7aa9e5613f 169 Gene3D G3DSA:1.20.120.520 5 145 2.9E-17 T 28-03-2018 CNX65_RS05100 cb129829c335501d2b9a5a7aa9e5613f 169 Pfam PF01814 Hemerythrin HHE cation binding domain 7 119 1.3E-9 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CNX65_RS19695 65bf2ec4105c79a92579b5f6b0b95cbe 353 Gene3D G3DSA:2.115.10.20 34 352 1.7E-55 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS19695 65bf2ec4105c79a92579b5f6b0b95cbe 353 SUPERFAMILY SSF75005 41 335 1.43E-53 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS19695 65bf2ec4105c79a92579b5f6b0b95cbe 353 Pfam PF04616 Glycosyl hydrolases family 43 43 334 6.1E-49 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS04180 a4fead94e968df68c7f256770bb323f2 479 Pfam PF07687 Peptidase dimerisation domain 208 369 9.1E-21 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS04180 a4fead94e968df68c7f256770bb323f2 479 Pfam PF01546 Peptidase family M20/M25/M40 95 465 9.1E-30 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS04180 a4fead94e968df68c7f256770bb323f2 479 Gene3D G3DSA:3.30.70.360 215 379 2.3E-52 T 28-03-2018 CNX65_RS04180 a4fead94e968df68c7f256770bb323f2 479 SUPERFAMILY SSF53187 18 211 4.0E-55 T 28-03-2018 CNX65_RS04180 a4fead94e968df68c7f256770bb323f2 479 SUPERFAMILY SSF53187 384 468 4.0E-55 T 28-03-2018 CNX65_RS04180 a4fead94e968df68c7f256770bb323f2 479 Gene3D G3DSA:3.40.630.10 15 214 3.1E-35 T 28-03-2018 CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 PRINTS PR00625 DnaJ domain signature 71 90 3.1E-8 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 PRINTS PR00625 DnaJ domain signature 38 53 3.1E-8 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 PRINTS PR00625 DnaJ domain signature 20 38 3.1E-8 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 Gene3D G3DSA:1.10.287.110 12 91 1.9E-20 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 Pfam PF00226 DnaJ domain 18 76 2.8E-17 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 Pfam PF08378 Nuclease-related domain 223 291 1.9E-6 T 28-03-2018 IPR011528 Nuclease-related domain, NERD CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 SUPERFAMILY SSF46565 17 89 1.09E-22 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 SMART SM00271 17 71 7.6E-19 T 28-03-2018 IPR001623 DnaJ domain CNX65_RS31805 c32d50856d973657563d1f8ef6c8587b 383 ProSitePatterns PS00636 Nt-dnaJ domain signature. 56 75 - T 28-03-2018 IPR018253 DnaJ domain, conserved site CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 Gene3D G3DSA:3.40.1280.10 150 321 2.8E-47 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 SUPERFAMILY SSF75217 142 317 3.07E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 77 152 1.1E-16 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 SUPERFAMILY SSF55315 70 149 3.77E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 Gene3D G3DSA:3.30.1330.30 45 148 4.1E-15 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 SMART SM00967 76 152 5.6E-16 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 76 316 3.8E-59 T 28-03-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 CNX65_RS01845 8e08d18381aa1f441ab5761a5bffd004 321 Pfam PF00588 SpoU rRNA Methylase family 169 309 3.0E-34 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CNX65_RS05350 206a4dd8d3ca37252014dede43322f41 161 Pfam PF03703 Bacterial PH domain 71 146 3.4E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CNX65_RS24230 c01f7bacbff9e2881a429b1aea41c9f3 351 Pfam PF01032 FecCD transport family 32 345 2.8E-84 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS24230 c01f7bacbff9e2881a429b1aea41c9f3 351 Gene3D G3DSA:1.10.3470.10 18 351 1.2E-57 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS24230 c01f7bacbff9e2881a429b1aea41c9f3 351 SUPERFAMILY SSF81345 19 345 1.57E-71 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS15570 8a4585202bea1b6baed8992dbb2ed8e9 262 Gene3D G3DSA:3.40.50.1110 13 217 1.1E-28 T 28-03-2018 CNX65_RS15570 8a4585202bea1b6baed8992dbb2ed8e9 262 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 17 192 1.1E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS15570 8a4585202bea1b6baed8992dbb2ed8e9 262 SUPERFAMILY SSF52266 13 201 8.16E-33 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS33380 1e183508db72a726a33a9ec6c2a348ad 107 Pfam PF10724 Protein of unknown function (DUF2516) 14 104 1.1E-29 T 28-03-2018 IPR019662 Protein of unknown function DUF2516 CNX65_RS03470 e4c790227ddd2ec7db80927345ced965 268 PIRSF PIRSF009160 1 268 1.9E-83 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 CNX65_RS03470 e4c790227ddd2ec7db80927345ced965 268 Pfam PF12811 Bax inhibitor 1 like 41 267 1.6E-85 T 28-03-2018 IPR010539 Protein of unknown function UCP009160 CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 Gene3D G3DSA:3.40.50.300 2 243 1.1E-71 T 28-03-2018 CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 SMART SM00382 28 209 2.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 Gene3D G3DSA:2.40.50.140 273 347 4.5E-6 T 28-03-2018 CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 Pfam PF08402 TOBE domain 270 353 3.0E-12 T 28-03-2018 IPR013611 Transport-associated OB, type 2 GO:0005215|GO:0005524|GO:0006810|GO:0016820|GO:0043190 CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 Pfam PF00005 ABC transporter 19 159 1.7E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 SUPERFAMILY SSF50331 235 353 8.5E-15 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CNX65_RS10515 8fcebfe3c5a6842ca3c33ac1a1f79ad8 356 SUPERFAMILY SSF52540 4 239 1.17E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08055 8c7359c66a0245b59d6ab7c89e507d3c 335 SUPERFAMILY SSF46894 268 316 6.12E-7 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS08055 8c7359c66a0245b59d6ab7c89e507d3c 335 SMART SM00421 267 316 0.0055 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08055 8c7359c66a0245b59d6ab7c89e507d3c 335 Gene3D G3DSA:1.10.10.10 187 321 7.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 Pfam PF02602 Uroporphyrinogen-III synthase HemD 10 250 6.8E-40 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 SUPERFAMILY SSF69618 1 254 3.14E-53 T 28-03-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 SUPERFAMILY SSF46894 267 353 2.66E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 Gene3D G3DSA:3.40.50.10090 153 260 6.1E-16 T 28-03-2018 CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 SMART SM00862 282 351 2.9E-14 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 Gene3D G3DSA:3.40.50.10090 30 152 4.0E-21 T 28-03-2018 CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 Gene3D G3DSA:1.10.10.10 261 358 1.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04145 e28c2a9ce7c90fe2cbdde522fd6a08ed 365 Pfam PF00486 Transcriptional regulatory protein, C terminal 289 351 4.8E-11 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS26690 5b52f188da65b65f7fc7635c48530bf7 138 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 33 130 3.9E-23 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS26690 5b52f188da65b65f7fc7635c48530bf7 138 SUPERFAMILY SSF52091 33 133 4.71E-21 T 28-03-2018 IPR002645 STAS domain CNX65_RS26690 5b52f188da65b65f7fc7635c48530bf7 138 Gene3D G3DSA:3.30.750.24 24 135 2.8E-20 T 28-03-2018 IPR002645 STAS domain CNX65_RS26690 5b52f188da65b65f7fc7635c48530bf7 138 Pfam PF13466 STAS domain 41 119 9.1E-15 T 28-03-2018 IPR002645 STAS domain CNX65_RS01625 089500787005f92f2116f429549288ee 125 TIGRFAM TIGR00526 folB_dom: FolB domain 9 125 3.9E-33 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CNX65_RS01625 089500787005f92f2116f429549288ee 125 Pfam PF02152 Dihydroneopterin aldolase 11 121 1.4E-33 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CNX65_RS01625 089500787005f92f2116f429549288ee 125 SMART SM00905 11 123 1.6E-49 T 28-03-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CNX65_RS01625 089500787005f92f2116f429549288ee 125 SUPERFAMILY SSF55620 9 125 6.67E-36 T 28-03-2018 CNX65_RS01625 089500787005f92f2116f429549288ee 125 Gene3D G3DSA:3.30.1130.10 7 125 3.6E-37 T 28-03-2018 CNX65_RS01625 089500787005f92f2116f429549288ee 125 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 9 123 8.5E-39 T 28-03-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 CNX65_RS20850 f713e74b0213844ec7749f602330164b 296 Gene3D G3DSA:3.40.50.720 1 107 3.8E-28 T 28-03-2018 CNX65_RS20850 f713e74b0213844ec7749f602330164b 296 SUPERFAMILY SSF51735 95 275 1.74E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20850 f713e74b0213844ec7749f602330164b 296 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 213 229 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CNX65_RS20850 f713e74b0213844ec7749f602330164b 296 Gene3D G3DSA:3.40.50.720 108 275 1.6E-46 T 28-03-2018 CNX65_RS20850 f713e74b0213844ec7749f602330164b 296 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 38 294 2.1E-23 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CNX65_RS20850 f713e74b0213844ec7749f602330164b 296 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 118 274 1.0E-53 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CNX65_RS20850 f713e74b0213844ec7749f602330164b 296 SUPERFAMILY SSF52283 1 114 3.59E-23 T 28-03-2018 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 SUPERFAMILY SSF53720 27 435 5.3E-68 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 Gene3D G3DSA:3.40.50.1980 28 233 5.1E-80 T 28-03-2018 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 5 436 37.857 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PIRSF PIRSF000099 2 438 7.1E-148 T 28-03-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 237 269 - T 28-03-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 Gene3D G3DSA:3.40.50.1980 234 380 1.2E-57 T 28-03-2018 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 35 59 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 208 233 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 136 162 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 259 278 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 329 354 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 370 388 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 173 199 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 PRINTS PR00083 Histidinol dehydrogenase signature 237 258 2.2E-85 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 35 435 1.4E-136 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS28045 d0ed3921d4f8be34cebb7a567ffa61c4 438 Pfam PF00815 Histidinol dehydrogenase 22 436 4.9E-152 T 28-03-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 CNX65_RS05405 37f44a7010f71ff53322a75f98204903 465 Gene3D G3DSA:2.60.120.200 33 314 8.6E-59 T 28-03-2018 CNX65_RS05405 37f44a7010f71ff53322a75f98204903 465 SUPERFAMILY SSF49785 330 464 4.25E-25 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS05405 37f44a7010f71ff53322a75f98204903 465 Gene3D G3DSA:2.60.120.260 326 465 1.6E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS05405 37f44a7010f71ff53322a75f98204903 465 Pfam PF03422 Carbohydrate binding module (family 6) 337 464 2.4E-29 T 28-03-2018 IPR005084 Carbohydrate binding module family 6 GO:0030246 CNX65_RS05405 37f44a7010f71ff53322a75f98204903 465 Pfam PF00722 Glycosyl hydrolases family 16 83 291 2.4E-11 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CNX65_RS05405 37f44a7010f71ff53322a75f98204903 465 SUPERFAMILY SSF49899 33 309 1.71E-46 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS05405 37f44a7010f71ff53322a75f98204903 465 SMART SM00606 329 465 2.9E-33 T 28-03-2018 IPR006584 Cellulose binding, type IV GO:0030246 CNX65_RS03960 525b06b6d7fc79251d18a18bffa4f682 201 Pfam PF06210 Protein of unknown function (DUF1003) 40 140 3.8E-41 T 28-03-2018 IPR010406 Protein of unknown function DUF1003 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 SMART SM00530 136 190 3.9E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 SUPERFAMILY SSF48452 293 399 7.59E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 SUPERFAMILY SSF48452 449 509 7.59E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 SUPERFAMILY SSF47413 126 179 1.45E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 Gene3D G3DSA:1.25.40.10 183 430 2.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 Gene3D G3DSA:1.25.40.10 452 553 1.9E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 Pfam PF13560 Helix-turn-helix domain 132 189 1.7E-12 T 28-03-2018 CNX65_RS04920 532f03065ee6f1c604007f7324127e28 564 Gene3D G3DSA:1.10.260.40 127 182 1.4E-13 T 28-03-2018 CNX65_RS20435 5f4e9e72aa232990d5d7874347db771c 163 SMART SM00903 15 162 5.1E-61 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS20435 5f4e9e72aa232990d5d7874347db771c 163 Gene3D G3DSA:2.30.110.10 4 163 8.3E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS20435 5f4e9e72aa232990d5d7874347db771c 163 SUPERFAMILY SSF50475 8 162 3.63E-50 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS20435 5f4e9e72aa232990d5d7874347db771c 163 Pfam PF01613 Flavin reductase like domain 15 162 3.3E-42 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 254 2.1E-73 T 28-03-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 135 147 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 Hamap MF_00186 Glycerol kinase [glpK]. 2 500 55.991 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 SUPERFAMILY SSF53067 257 500 1.26E-83 T 28-03-2018 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 SUPERFAMILY SSF53067 3 257 5.34E-88 T 28-03-2018 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 28-03-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 Gene3D G3DSA:3.30.420.40 251 504 4.4E-80 T 28-03-2018 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 263 453 4.4E-66 T 28-03-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 Gene3D G3DSA:3.30.420.40 1 250 3.9E-88 T 28-03-2018 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 3 499 1.3E-224 T 28-03-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 CNX65_RS31455 9c54d100e7e06d18115f30896c0784b8 504 PIRSF PIRSF000538 2 504 1.6E-170 T 28-03-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 CNX65_RS06550 ada309d2499a91877ad0748160d59869 325 Gene3D G3DSA:3.40.47.10 171 324 1.1E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS06550 ada309d2499a91877ad0748160d59869 325 Gene3D G3DSA:3.40.47.10 12 170 2.0E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS06550 ada309d2499a91877ad0748160d59869 325 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 116 192 5.2E-25 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS06550 ada309d2499a91877ad0748160d59869 325 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 232 323 1.1E-28 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS06550 ada309d2499a91877ad0748160d59869 325 SUPERFAMILY SSF53901 7 324 8.8E-61 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS06550 ada309d2499a91877ad0748160d59869 325 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 13 323 2.3E-99 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS06550 ada309d2499a91877ad0748160d59869 325 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 11 324 57.889 T 28-03-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS10005 ffabf0069dd1f15b82625251607420bb 193 Gene3D G3DSA:1.10.357.10 6 193 5.0E-36 T 28-03-2018 CNX65_RS10005 ffabf0069dd1f15b82625251607420bb 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10005 ffabf0069dd1f15b82625251607420bb 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 1.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10005 ffabf0069dd1f15b82625251607420bb 193 SUPERFAMILY SSF46689 11 89 1.75E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS10005 ffabf0069dd1f15b82625251607420bb 193 SUPERFAMILY SSF48498 89 191 2.6E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS10005 ffabf0069dd1f15b82625251607420bb 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 9.7E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS32355 05ea399686d3d8390a4ffbc55390ef8e 147 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 141 - T 28-03-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32355 05ea399686d3d8390a4ffbc55390ef8e 147 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 145 1.2E-31 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CNX65_RS32355 05ea399686d3d8390a4ffbc55390ef8e 147 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 5 147 19.358 T 28-03-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 CNX65_RS32355 05ea399686d3d8390a4ffbc55390ef8e 147 SUPERFAMILY SSF52080 7 146 1.16E-38 T 28-03-2018 IPR021131 Ribosomal protein L18e/L15P CNX65_RS32355 05ea399686d3d8390a4ffbc55390ef8e 147 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 4 144 1.7E-42 T 28-03-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32355 05ea399686d3d8390a4ffbc55390ef8e 147 Gene3D G3DSA:3.100.10.10 39 147 3.6E-28 T 28-03-2018 CNX65_RS03095 89e522183b7f96c4d671055dfdafd16c 182 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 2 127 9.5E-31 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CNX65_RS03095 89e522183b7f96c4d671055dfdafd16c 182 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 78 86 2.1E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CNX65_RS03095 89e522183b7f96c4d671055dfdafd16c 182 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 88 97 2.1E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CNX65_RS03095 89e522183b7f96c4d671055dfdafd16c 182 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 2.1E-8 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CNX65_RS03095 89e522183b7f96c4d671055dfdafd16c 182 SUPERFAMILY SSF81330 10 122 4.32E-28 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CNX65_RS03095 89e522183b7f96c4d671055dfdafd16c 182 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 2 125 7.6E-38 T 28-03-2018 IPR001185 Large-conductance mechanosensitive channel GO:0005216|GO:0006810|GO:0016021 CNX65_RS03095 89e522183b7f96c4d671055dfdafd16c 182 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 28-03-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site CNX65_RS12210 4db4cfb61f5ea094f12a850d3c99504a 285 SUPERFAMILY SSF51679 1 225 3.66E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS12210 4db4cfb61f5ea094f12a850d3c99504a 285 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 23 262 2.2E-54 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CNX65_RS12210 4db4cfb61f5ea094f12a850d3c99504a 285 Gene3D G3DSA:3.20.20.30 1 284 2.5E-49 T 28-03-2018 CNX65_RS12210 4db4cfb61f5ea094f12a850d3c99504a 285 Pfam PF00296 Luciferase-like monooxygenase 2 219 1.2E-39 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 Gene3D G3DSA:3.40.190.10 176 263 3.7E-11 T 28-03-2018 CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 Pfam PF03466 LysR substrate binding domain 101 287 2.1E-25 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 SUPERFAMILY SSF53850 102 286 2.02E-24 T 28-03-2018 CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 23 34 3.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 34 44 3.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 44 55 3.4E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 Gene3D G3DSA:1.10.10.10 1 87 1.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 8 67 1.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 SUPERFAMILY SSF46785 6 89 2.83E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23810 3a033687b4b3ae984db4f5574b2a543c 290 Gene3D G3DSA:3.40.190.10 95 175 1.4E-17 T 28-03-2018 CNX65_RS09815 f35d5ec1b093d3e7be0f94e141343bea 151 Gene3D G3DSA:1.10.10.10 2 150 3.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09815 f35d5ec1b093d3e7be0f94e141343bea 151 SUPERFAMILY SSF46785 7 148 3.46E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09815 f35d5ec1b093d3e7be0f94e141343bea 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 8.5E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS09815 f35d5ec1b093d3e7be0f94e141343bea 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 8.5E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS09815 f35d5ec1b093d3e7be0f94e141343bea 151 PRINTS PR00598 Bacterial regulatory protein MarR family signature 59 75 8.5E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS09815 f35d5ec1b093d3e7be0f94e141343bea 151 SMART SM00347 35 135 4.4E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS09815 f35d5ec1b093d3e7be0f94e141343bea 151 Pfam PF01047 MarR family 42 99 2.2E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS05605 64a176f5d982ad6e6f3443864a0a4187 176 SUPERFAMILY SSF50249 7 137 5.14E-20 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS05605 64a176f5d982ad6e6f3443864a0a4187 176 Gene3D G3DSA:2.40.50.140 1 119 1.4E-21 T 28-03-2018 CNX65_RS05605 64a176f5d982ad6e6f3443864a0a4187 176 Pfam PF00436 Single-strand binding protein family 7 105 1.1E-9 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CNX65_RS34025 7b7c2e9174164aadf622b67d42876176 285 SMART SM00062 50 278 1.2E-30 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS34025 7b7c2e9174164aadf622b67d42876176 285 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 51 276 1.7E-40 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS34025 7b7c2e9174164aadf622b67d42876176 285 SMART SM00079 50 277 8.2E-5 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CNX65_RS34025 7b7c2e9174164aadf622b67d42876176 285 Gene3D G3DSA:3.40.190.10 44 152 4.3E-17 T 28-03-2018 CNX65_RS34025 7b7c2e9174164aadf622b67d42876176 285 Gene3D G3DSA:3.40.190.10 153 241 7.5E-16 T 28-03-2018 CNX65_RS34025 7b7c2e9174164aadf622b67d42876176 285 SUPERFAMILY SSF53850 5 275 1.66E-46 T 28-03-2018 CNX65_RS29500 32e0a530cb6a47d6125c8275ee780734 204 Gene3D G3DSA:3.90.550.10 2 166 1.8E-8 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS29500 32e0a530cb6a47d6125c8275ee780734 204 Pfam PF01983 Guanylyl transferase CofC like 7 152 2.2E-6 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CNX65_RS29500 32e0a530cb6a47d6125c8275ee780734 204 SUPERFAMILY SSF53448 8 193 1.5E-20 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS29500 32e0a530cb6a47d6125c8275ee780734 204 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 7 190 4.8E-42 T 28-03-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 CNX65_RS29805 8301facc74019dcd1d5891f96796b360 499 SUPERFAMILY SSF88688 391 497 5.23E-17 T 28-03-2018 IPR028995 Glycoside hydrolase families 57/38, central domain CNX65_RS29805 8301facc74019dcd1d5891f96796b360 499 Gene3D G3DSA:3.20.110.10 3 382 1.6E-87 T 28-03-2018 IPR027291 Glycoside hydrolase 38/57, N-terminal domain CNX65_RS29805 8301facc74019dcd1d5891f96796b360 499 Pfam PF09210 Domain of unknown function (DUF1957) 411 497 1.2E-18 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CNX65_RS29805 8301facc74019dcd1d5891f96796b360 499 SUPERFAMILY SSF88713 6 383 8.9E-94 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS29805 8301facc74019dcd1d5891f96796b360 499 Pfam PF03065 Glycosyl hydrolase family 57 10 333 2.8E-21 T 28-03-2018 IPR004300 Glycoside hydrolase family 57, N-terminal domain GO:0003824|GO:0005975 CNX65_RS29805 8301facc74019dcd1d5891f96796b360 499 Gene3D G3DSA:1.20.1430.10 383 499 3.6E-24 T 28-03-2018 IPR015293 Domain of unknown function DUF1957 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622 CNX65_RS00640 d7d77ac00900e776dffb38f8e958aa3b 543 Gene3D G3DSA:3.40.50.2000 327 521 3.9E-25 T 28-03-2018 CNX65_RS00640 d7d77ac00900e776dffb38f8e958aa3b 543 SUPERFAMILY SSF53756 184 513 9.77E-37 T 28-03-2018 CNX65_RS00640 d7d77ac00900e776dffb38f8e958aa3b 543 Pfam PF00534 Glycosyl transferases group 1 354 511 1.7E-18 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 Gene3D G3DSA:1.10.10.10 132 215 1.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 Pfam PF00072 Response regulator receiver domain 3 108 7.7E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 2.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 2.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 2.3E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 SMART SM00448 1 120 3.6E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 Gene3D G3DSA:3.40.50.2300 1 131 7.5E-29 T 28-03-2018 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 SMART SM00421 148 211 2.1E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 Pfam PF00196 Bacterial regulatory proteins, luxR family 151 196 1.1E-11 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS15500 c10879bad75dbe3df923ba0a93c2846a 216 SUPERFAMILY SSF52172 2 176 8.01E-23 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS32995 ed7afa9a7c95084e70c110bd0376116c 359 SUPERFAMILY SSF53686 28 340 5.5E-70 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS32995 ed7afa9a7c95084e70c110bd0376116c 359 Gene3D G3DSA:3.40.50.1100 147 335 9.1E-39 T 28-03-2018 CNX65_RS32995 ed7afa9a7c95084e70c110bd0376116c 359 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 38 320 1.3E-43 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS32995 ed7afa9a7c95084e70c110bd0376116c 359 Gene3D G3DSA:3.40.50.1100 36 146 1.4E-22 T 28-03-2018 CNX65_RS02325 5e76272203266b4bdbcde3ee6e8dfd9b 1092 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 556 663 2.0E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02325 5e76272203266b4bdbcde3ee6e8dfd9b 1092 SMART SM00387 552 665 8.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02325 5e76272203266b4bdbcde3ee6e8dfd9b 1092 Pfam PF00672 HAMP domain 368 437 2.8E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS02325 5e76272203266b4bdbcde3ee6e8dfd9b 1092 SUPERFAMILY SSF55874 539 662 4.98E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02325 5e76272203266b4bdbcde3ee6e8dfd9b 1092 Gene3D G3DSA:3.30.565.10 473 663 1.4E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02325 5e76272203266b4bdbcde3ee6e8dfd9b 1092 Pfam PF08376 Nitrate and nitrite sensing 90 330 5.0E-39 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CNX65_RS21760 92794b8bb5aa468dd7d5aeaf52d0baa4 406 ProSitePatterns PS00216 Sugar transport proteins signature 1. 78 94 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS21760 92794b8bb5aa468dd7d5aeaf52d0baa4 406 Pfam PF07690 Major Facilitator Superfamily 34 367 1.3E-42 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS21760 92794b8bb5aa468dd7d5aeaf52d0baa4 406 SUPERFAMILY SSF103473 12 402 4.05E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS21760 92794b8bb5aa468dd7d5aeaf52d0baa4 406 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 23 398 8.8E-92 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CNX65_RS21760 92794b8bb5aa468dd7d5aeaf52d0baa4 406 Gene3D G3DSA:1.20.1250.20 3 219 6.5E-33 T 28-03-2018 CNX65_RS21760 92794b8bb5aa468dd7d5aeaf52d0baa4 406 Gene3D G3DSA:1.20.1250.20 220 406 1.8E-12 T 28-03-2018 CNX65_RS17215 ba89bb4e3e456335e6d787be38581916 320 Gene3D G3DSA:1.10.10.10 2 66 9.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17215 ba89bb4e3e456335e6d787be38581916 320 Pfam PF13280 WYL domain 144 314 1.1E-36 T 28-03-2018 IPR026881 WYL domain CNX65_RS17215 ba89bb4e3e456335e6d787be38581916 320 PIRSF PIRSF016838 3 53 0.61 T 28-03-2018 IPR028349 Protein PafC CNX65_RS17215 ba89bb4e3e456335e6d787be38581916 320 PIRSF PIRSF016838 68 320 1.6E-19 T 28-03-2018 IPR028349 Protein PafC CNX65_RS17215 ba89bb4e3e456335e6d787be38581916 320 Pfam PF08279 HTH domain 7 62 3.5E-10 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CNX65_RS17215 ba89bb4e3e456335e6d787be38581916 320 SUPERFAMILY SSF46785 9 67 3.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26220 49b8dd0d243f11c006839b242bfbff00 395 Gene3D G3DSA:2.60.120.650 23 230 1.0E-21 T 28-03-2018 CNX65_RS26220 49b8dd0d243f11c006839b242bfbff00 395 SMART SM00558 79 239 0.0012 T 28-03-2018 IPR003347 JmjC domain CNX65_RS26220 49b8dd0d243f11c006839b242bfbff00 395 Pfam PF08007 Cupin superfamily protein 17 260 4.6E-35 T 28-03-2018 IPR003347 JmjC domain CNX65_RS26220 49b8dd0d243f11c006839b242bfbff00 395 SUPERFAMILY SSF51197 14 281 2.33E-38 T 28-03-2018 CNX65_RS18165 a0b06b47e6e7d3930124b1e6fc0e4962 118 Pfam PF02553 Cobalt transport protein component CbiN 7 74 5.9E-26 T 28-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CNX65_RS18165 a0b06b47e6e7d3930124b1e6fc0e4962 118 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 114 34.634 T 28-03-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 CNX65_RS15655 e31908a28be4ca05fcaf509951abbf07 172 Gene3D G3DSA:3.40.1580.10 21 160 1.8E-9 T 28-03-2018 CNX65_RS15655 e31908a28be4ca05fcaf509951abbf07 172 SUPERFAMILY SSF160631 35 140 5.23E-7 T 28-03-2018 CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 Pfam PF00553 Cellulose binding domain 353 443 6.9E-25 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 148 157 - T 28-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 41 284 7.1E-29 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 SMART SM00637 353 446 2.8E-38 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 SUPERFAMILY SSF51445 32 322 2.86E-68 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 Gene3D G3DSA:3.20.20.80 20 324 9.5E-50 T 28-03-2018 CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 SUPERFAMILY SSF49384 347 444 3.91E-29 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS20770 20e6f26bb585816f8f60c69d3ac2e224 449 Gene3D G3DSA:2.60.40.290 350 449 6.6E-33 T 28-03-2018 CNX65_RS05690 2b376e413490da9be1b350913330c0ed 204 Gene3D G3DSA:3.40.30.10 59 165 1.1E-11 T 28-03-2018 CNX65_RS05690 2b376e413490da9be1b350913330c0ed 204 Gene3D G3DSA:3.40.30.10 5 58 3.4E-10 T 28-03-2018 CNX65_RS05690 2b376e413490da9be1b350913330c0ed 204 SUPERFAMILY SSF52833 7 164 3.5E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS05690 2b376e413490da9be1b350913330c0ed 204 Pfam PF01323 DSBA-like thioredoxin domain 8 162 3.3E-7 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CNX65_RS09080 c563362fb88383ec917c45f75fbd7660 111 Gene3D G3DSA:3.30.750.24 3 110 2.4E-14 T 28-03-2018 IPR002645 STAS domain CNX65_RS09080 c563362fb88383ec917c45f75fbd7660 111 SUPERFAMILY SSF52091 11 105 3.73E-17 T 28-03-2018 IPR002645 STAS domain CNX65_RS09080 c563362fb88383ec917c45f75fbd7660 111 Pfam PF13466 STAS domain 19 97 3.3E-13 T 28-03-2018 IPR002645 STAS domain CNX65_RS02475 5729635630813673f1c985a1d837fcbc 942 Gene3D G3DSA:3.30.565.10 38 192 1.6E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02475 5729635630813673f1c985a1d837fcbc 942 SUPERFAMILY SSF55874 43 131 3.91E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 Gene3D G3DSA:3.30.450.20 33 166 1.2E-28 T 28-03-2018 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 Gene3D G3DSA:3.30.450.20 218 314 1.3E-8 T 28-03-2018 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 SUPERFAMILY SSF55874 385 522 1.7E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 Gene3D G3DSA:3.30.565.10 380 527 4.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 421 523 5.5E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 SUPERFAMILY SSF55890 322 365 1.26E-10 T 28-03-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 Pfam PF17203 Single cache domain 3 39 171 1.2E-33 T 28-03-2018 IPR033463 Single cache domain 3 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 Gene3D G3DSA:1.10.287.130 315 376 2.6E-16 T 28-03-2018 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 321 365 8.8E-12 T 28-03-2018 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 484 502 2.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 509 522 2.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 PRINTS PR00344 Bacterial sensor protein C-terminal signature 451 465 2.8E-9 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 SMART SM00387 415 525 9.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18560 b68acf2c892dd3a66007bda76dc91ea2 527 SUPERFAMILY SSF103190 40 167 4.71E-36 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CNX65_RS17370 b4c5dd7c08e134632e621e38dbb60001 136 Gene3D G3DSA:3.40.50.2300 4 136 5.6E-37 T 28-03-2018 CNX65_RS17370 b4c5dd7c08e134632e621e38dbb60001 136 SUPERFAMILY SSF52788 5 128 6.02E-36 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS17370 b4c5dd7c08e134632e621e38dbb60001 136 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 128 1.7E-22 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS17370 b4c5dd7c08e134632e621e38dbb60001 136 SMART SM00226 5 130 7.9E-40 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS25625 349d108108c828a426dc0a20597e38dd 112 Gene3D G3DSA:2.102.10.10 2 110 9.7E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS25625 349d108108c828a426dc0a20597e38dd 112 Pfam PF00355 Rieske [2Fe-2S] domain 4 90 1.2E-15 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS25625 349d108108c828a426dc0a20597e38dd 112 SUPERFAMILY SSF50022 3 100 1.44E-24 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 SUPERFAMILY SSF52540 281 484 1.89E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 Pfam PF02881 SRP54-type protein, helical bundle domain 202 265 3.0E-9 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 212 485 57.217 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 Pfam PF00448 SRP54-type protein, GTPase domain 286 485 2.2E-71 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 SMART SM00962 286 485 1.2E-99 T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 SMART SM00382 285 435 7.6E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 SUPERFAMILY SSF47364 184 263 3.93E-17 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 Gene3D G3DSA:1.20.120.140 398 485 4.2E-23 T 28-03-2018 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 Gene3D G3DSA:3.40.50.300 264 397 2.9E-13 T 28-03-2018 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 213 484 3.2E-102 T 28-03-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 458 471 - T 28-03-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 SMART SM00963 189 269 1.0E-17 T 28-03-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 CNX65_RS29185 bfe829eaabdf6f775f4f07f1433cf412 485 Gene3D G3DSA:1.20.120.140 185 263 1.4E-15 T 28-03-2018 CNX65_RS33785 6bad4979b86e46c6e3a2a7824331d45c 285 SUPERFAMILY SSF50891 171 282 7.21E-14 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS33785 6bad4979b86e46c6e3a2a7824331d45c 285 SMART SM00797 25 285 1.0E-91 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CNX65_RS33785 6bad4979b86e46c6e3a2a7824331d45c 285 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 282 2.3E-80 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CNX65_RS33785 6bad4979b86e46c6e3a2a7824331d45c 285 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 4 282 8.5E-80 T 28-03-2018 IPR003778 Carboxyltransferase domain, subdomain A and B CNX65_RS24965 934805a42db6da4b92124e6afd86bd13 394 Gene3D G3DSA:3.50.50.60 2 394 2.7E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24965 934805a42db6da4b92124e6afd86bd13 394 Pfam PF01593 Flavin containing amine oxidoreductase 11 384 1.1E-39 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS24965 934805a42db6da4b92124e6afd86bd13 394 SUPERFAMILY SSF51905 2 273 1.36E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24965 934805a42db6da4b92124e6afd86bd13 394 SUPERFAMILY SSF51905 348 387 1.36E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23915 67360418a4ce94fb150ddf06db1bbf5e 139 SMART SM00960 9 101 1.1E-25 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS23915 67360418a4ce94fb150ddf06db1bbf5e 139 Gene3D G3DSA:3.30.450.30 4 133 6.9E-38 T 28-03-2018 CNX65_RS23915 67360418a4ce94fb150ddf06db1bbf5e 139 Pfam PF03259 Roadblock/LC7 domain 8 101 1.8E-22 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS23915 67360418a4ce94fb150ddf06db1bbf5e 139 SUPERFAMILY SSF103196 2 130 5.58E-33 T 28-03-2018 CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 SUPERFAMILY SSF51206 4 142 1.83E-37 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 Gene3D G3DSA:1.10.10.10 144 224 2.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 Pfam PF00027 Cyclic nucleotide-binding domain 29 114 7.6E-25 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 Pfam PF13545 Crp-like helix-turn-helix domain 148 221 1.0E-18 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 PRINTS PR00103 cAMP-dependent protein kinase signature 76 85 8.7E-5 T 28-03-2018 CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 PRINTS PR00103 cAMP-dependent protein kinase signature 88 99 8.7E-5 T 28-03-2018 CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 PRINTS PR00103 cAMP-dependent protein kinase signature 46 60 8.7E-5 T 28-03-2018 CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 PRINTS PR00103 cAMP-dependent protein kinase signature 31 45 8.7E-5 T 28-03-2018 CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 SMART SM00419 167 215 2.2E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 Gene3D G3DSA:2.60.120.10 1 143 9.6E-36 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 SUPERFAMILY SSF46785 145 223 4.21E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01195 2953e0c0c295fa62dc3ae589e4859e0c 224 SMART SM00100 10 128 1.6E-28 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS10040 1a6245353de7dcd5f415c5266fc78562 293 SUPERFAMILY SSF50494 86 267 8.69E-18 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS10040 1a6245353de7dcd5f415c5266fc78562 293 Gene3D G3DSA:2.40.10.10 191 293 7.1E-31 T 28-03-2018 CNX65_RS10040 1a6245353de7dcd5f415c5266fc78562 293 Gene3D G3DSA:2.40.10.10 72 190 1.2E-8 T 28-03-2018 CNX65_RS10040 1a6245353de7dcd5f415c5266fc78562 293 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 114 119 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS07480 7ded02ab0d1feb5fead59078b3ca856f 253 Gene3D G3DSA:3.30.420.40 5 123 9.7E-21 T 28-03-2018 CNX65_RS07480 7ded02ab0d1feb5fead59078b3ca856f 253 Pfam PF00480 ROK family 8 166 1.7E-15 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS07480 7ded02ab0d1feb5fead59078b3ca856f 253 SUPERFAMILY SSF53067 7 248 6.74E-34 T 28-03-2018 CNX65_RS07480 7ded02ab0d1feb5fead59078b3ca856f 253 Gene3D G3DSA:3.30.420.40 124 251 1.2E-26 T 28-03-2018 CNX65_RS18030 0a8872bcf256f916dea5dc64a0ebba12 391 Pfam PF07690 Major Facilitator Superfamily 16 353 2.7E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS18030 0a8872bcf256f916dea5dc64a0ebba12 391 Gene3D G3DSA:1.20.1250.20 200 389 1.3E-23 T 28-03-2018 CNX65_RS18030 0a8872bcf256f916dea5dc64a0ebba12 391 Gene3D G3DSA:1.20.1250.20 10 199 1.1E-15 T 28-03-2018 CNX65_RS18030 0a8872bcf256f916dea5dc64a0ebba12 391 SUPERFAMILY SSF103473 12 386 3.4E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS14410 b455fa6d64380875bd99e32c8bee0bba 239 Gene3D G3DSA:3.40.50.1820 2 225 2.4E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14410 b455fa6d64380875bd99e32c8bee0bba 239 SUPERFAMILY SSF53474 3 222 4.55E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14410 b455fa6d64380875bd99e32c8bee0bba 239 Pfam PF12697 Alpha/beta hydrolase family 3 218 3.6E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS06865 7a77ff9292028c2363fa2fa16c387488 401 SUPERFAMILY SSF52540 5 286 1.18E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06865 7a77ff9292028c2363fa2fa16c387488 401 Pfam PF02374 Anion-transporting ATPase 5 309 1.0E-59 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CNX65_RS06865 7a77ff9292028c2363fa2fa16c387488 401 TIGRFAM TIGR00345 GET3_arsA_TRC40: transport-energizing ATPase, TRC40/GET3/ArsA family 7 305 3.6E-55 T 28-03-2018 IPR016300 Arsenical pump ATPase, ArsA/GET3 GO:0005524|GO:0016887 Reactome: R-HSA-381038 CNX65_RS06865 7a77ff9292028c2363fa2fa16c387488 401 Gene3D G3DSA:3.40.50.300 3 322 2.5E-59 T 28-03-2018 CNX65_RS23660 9eb1870779a710bf00474fa177d34869 181 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 59 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23660 9eb1870779a710bf00474fa177d34869 181 Gene3D G3DSA:1.10.357.10 57 180 1.6E-22 T 28-03-2018 CNX65_RS23660 9eb1870779a710bf00474fa177d34869 181 SUPERFAMILY SSF48498 76 177 3.34E-18 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS23660 9eb1870779a710bf00474fa177d34869 181 SUPERFAMILY SSF46689 3 73 4.13E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23660 9eb1870779a710bf00474fa177d34869 181 Pfam PF13305 WHG domain 83 161 3.2E-18 T 28-03-2018 IPR025996 WHG domain CNX65_RS23660 9eb1870779a710bf00474fa177d34869 181 Gene3D G3DSA:1.10.10.60 5 56 1.8E-13 T 28-03-2018 CNX65_RS08530 e793dda835f084d759235bb2e7b427f5 458 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 15 141 4.1E-21 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS08530 e793dda835f084d759235bb2e7b427f5 458 TIGRFAM TIGR03084 TIGR03084: TIGR03084 family protein 11 251 3.0E-90 T 28-03-2018 IPR017518 Conserved hypothetical protein CHP03084 CNX65_RS08530 e793dda835f084d759235bb2e7b427f5 458 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 16 218 6.7E-39 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS08530 e793dda835f084d759235bb2e7b427f5 458 Gene3D G3DSA:1.20.120.450 9 147 2.8E-16 T 28-03-2018 CNX65_RS08530 e793dda835f084d759235bb2e7b427f5 458 SUPERFAMILY SSF109854 7 146 2.22E-24 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS28890 dd3a99dfb7d5b5040afb21d7acbdd7df 385 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 18 369 33.283 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CNX65_RS28890 dd3a99dfb7d5b5040afb21d7acbdd7df 385 Pfam PF04551 GcpE protein 23 363 1.6E-132 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CNX65_RS28890 dd3a99dfb7d5b5040afb21d7acbdd7df 385 SUPERFAMILY SSF56014 278 360 5.23E-11 T 28-03-2018 CNX65_RS28890 dd3a99dfb7d5b5040afb21d7acbdd7df 385 PIRSF PIRSF004640 14 375 2.8E-143 T 28-03-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CNX65_RS28890 dd3a99dfb7d5b5040afb21d7acbdd7df 385 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 20 362 2.0E-126 T 28-03-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 CNX65_RS28890 dd3a99dfb7d5b5040afb21d7acbdd7df 385 SUPERFAMILY SSF51717 49 221 1.26E-8 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS28890 dd3a99dfb7d5b5040afb21d7acbdd7df 385 Gene3D G3DSA:3.20.20.120 31 202 6.5E-18 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS23345 12ca07a996145b33e5e9fb12802b2d75 367 Gene3D G3DSA:3.40.710.10 25 364 3.4E-56 T 28-03-2018 CNX65_RS23345 12ca07a996145b33e5e9fb12802b2d75 367 SUPERFAMILY SSF56601 30 348 4.51E-58 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS23345 12ca07a996145b33e5e9fb12802b2d75 367 Pfam PF00144 Beta-lactamase 45 349 5.5E-46 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS04460 9251722cbc1d3f9f016a7fd084b473eb 1361 Gene3D G3DSA:3.40.50.150 1121 1322 1.4E-20 T 28-03-2018 CNX65_RS04460 9251722cbc1d3f9f016a7fd084b473eb 1361 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 1135 1282 1.0E-13 T 28-03-2018 IPR006342 Methyltransferase FkbM CNX65_RS04460 9251722cbc1d3f9f016a7fd084b473eb 1361 Gene3D G3DSA:3.40.50.2000 663 837 1.6E-10 T 28-03-2018 CNX65_RS04460 9251722cbc1d3f9f016a7fd084b473eb 1361 Pfam PF05050 Methyltransferase FkbM domain 1137 1306 1.2E-9 T 28-03-2018 IPR006342 Methyltransferase FkbM CNX65_RS04460 9251722cbc1d3f9f016a7fd084b473eb 1361 SUPERFAMILY SSF53335 1093 1307 3.81E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS04460 9251722cbc1d3f9f016a7fd084b473eb 1361 SUPERFAMILY SSF53756 632 850 9.42E-9 T 28-03-2018 CNX65_RS26865 bc9ccd2ab822640f98457fe074a49070 282 Pfam PF13560 Helix-turn-helix domain 16 75 4.1E-14 T 28-03-2018 CNX65_RS26865 bc9ccd2ab822640f98457fe074a49070 282 Gene3D G3DSA:1.10.3100.10 8 164 3.0E-15 T 28-03-2018 IPR027910 YdiL-like domain CNX65_RS26865 bc9ccd2ab822640f98457fe074a49070 282 SUPERFAMILY SSF47413 12 72 4.86E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS26865 bc9ccd2ab822640f98457fe074a49070 282 SMART SM00530 17 72 5.5E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS28700 1879d3970d9dcf291b03e71e40d3264e 229 SUPERFAMILY SSF51206 22 142 4.32E-24 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS28700 1879d3970d9dcf291b03e71e40d3264e 229 Gene3D G3DSA:2.60.120.10 10 145 1.6E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS28700 1879d3970d9dcf291b03e71e40d3264e 229 Pfam PF00027 Cyclic nucleotide-binding domain 33 117 1.9E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS28700 1879d3970d9dcf291b03e71e40d3264e 229 SUPERFAMILY SSF46785 150 227 1.61E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28700 1879d3970d9dcf291b03e71e40d3264e 229 SMART SM00100 13 131 1.8E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS28700 1879d3970d9dcf291b03e71e40d3264e 229 Gene3D G3DSA:1.10.10.10 148 229 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28700 1879d3970d9dcf291b03e71e40d3264e 229 Pfam PF13545 Crp-like helix-turn-helix domain 152 226 4.7E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS20090 20abbc258d7a480373ef14b94c74d1d9 266 Pfam PF00561 alpha/beta hydrolase fold 22 249 2.1E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20090 20abbc258d7a480373ef14b94c74d1d9 266 SUPERFAMILY SSF53474 6 264 1.07E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20090 20abbc258d7a480373ef14b94c74d1d9 266 Gene3D G3DSA:3.40.50.1820 3 265 5.7E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20090 20abbc258d7a480373ef14b94c74d1d9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 4.8E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20090 20abbc258d7a480373ef14b94c74d1d9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 4.8E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20090 20abbc258d7a480373ef14b94c74d1d9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 209 223 4.8E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS20090 20abbc258d7a480373ef14b94c74d1d9 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 4.8E-11 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS14845 594489d1384d7b03a98645ead542ccfe 650 Pfam PF04865 Baseplate J-like protein 404 574 2.8E-14 T 28-03-2018 IPR006949 Baseplate protein J-like CNX65_RS14845 594489d1384d7b03a98645ead542ccfe 650 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 6 613 8.8E-169 T 28-03-2018 IPR011749 Conserved hypothetical protein CHP02243 CNX65_RS14265 623c07a0596835aedc28308437ab6d33 280 Pfam PF01569 PAP2 superfamily 96 263 4.6E-14 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS14265 623c07a0596835aedc28308437ab6d33 280 Gene3D G3DSA:1.20.144.10 8 277 1.3E-13 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS14265 623c07a0596835aedc28308437ab6d33 280 SUPERFAMILY SSF48317 225 263 2.52E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS14265 623c07a0596835aedc28308437ab6d33 280 SUPERFAMILY SSF48317 33 153 2.52E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS20400 3ddff99906e6e3411e553f6ac9c5bd66 400 SUPERFAMILY SSF53383 3 397 2.26E-77 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS20400 3ddff99906e6e3411e553f6ac9c5bd66 400 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 393 3.4E-128 T 28-03-2018 IPR011340 Cysteine desulfurase-related CNX65_RS20400 3ddff99906e6e3411e553f6ac9c5bd66 400 Gene3D G3DSA:3.40.640.10 29 263 1.5E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS20400 3ddff99906e6e3411e553f6ac9c5bd66 400 Pfam PF00266 Aminotransferase class-V 22 390 2.3E-53 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS20400 3ddff99906e6e3411e553f6ac9c5bd66 400 Gene3D G3DSA:3.90.1150.10 264 396 1.1E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 Gene3D G3DSA:3.90.180.10 2 191 2.0E-58 T 28-03-2018 CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 SMART SM00829 11 341 8.2E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 143 1.7E-29 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 SUPERFAMILY SSF50129 7 173 1.83E-55 T 28-03-2018 IPR011032 GroES-like CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 Gene3D G3DSA:3.40.50.20 192 274 2.1E-16 T 28-03-2018 CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 Gene3D G3DSA:3.40.50.20 275 340 6.7E-5 T 28-03-2018 CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 SUPERFAMILY SSF51735 148 311 1.9E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS19835 d26a7f14b2331d4e282b24ec0960b7e4 348 Pfam PF00107 Zinc-binding dehydrogenase 185 307 2.0E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS25905 6e644edcfaf32284084556766130b109 136 SUPERFAMILY SSF50022 15 135 4.06E-23 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS25905 6e644edcfaf32284084556766130b109 136 Pfam PF00355 Rieske [2Fe-2S] domain 46 125 1.5E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS25905 6e644edcfaf32284084556766130b109 136 Gene3D G3DSA:2.102.10.10 34 136 1.5E-18 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 Pfam PF00512 His Kinase A (phospho-acceptor) domain 237 298 6.7E-11 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 Gene3D G3DSA:3.30.565.10 304 451 8.4E-31 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 SUPERFAMILY SSF55874 310 447 3.41E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 SUPERFAMILY SSF47384 217 298 2.75E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 448 6.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 SUPERFAMILY SSF158472 184 230 6.15E-8 T 28-03-2018 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 SMART SM00388 234 301 1.2E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 Gene3D G3DSA:1.10.287.130 223 297 2.0E-10 T 28-03-2018 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 SMART SM00387 339 450 2.4E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 Pfam PF00672 HAMP domain 183 230 4.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 410 428 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 392 402 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 447 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 388 6.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS20215 45b96b4a81783de2645460435e8819e0 451 SMART SM00304 181 233 1.3E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS10660 4a45c7c6f0c977f91ebbfeab189e7920 215 Pfam PF01066 CDP-alcohol phosphatidyltransferase 27 91 2.7E-10 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS10660 4a45c7c6f0c977f91ebbfeab189e7920 215 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 69 91 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS20510 8662cbe966590427ef3e755cf677e317 292 SUPERFAMILY SSF109854 21 172 3.14E-14 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS20510 8662cbe966590427ef3e755cf677e317 292 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 29 168 9.9E-10 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS20510 8662cbe966590427ef3e755cf677e317 292 Gene3D G3DSA:1.20.120.450 5 174 6.0E-16 T 28-03-2018 CNX65_RS20510 8662cbe966590427ef3e755cf677e317 292 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 27 234 5.3E-14 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS21465 286135a2037cc90de5d0c0b82c7c0542 295 Pfam PF03239 Iron permease FTR1 family 21 274 2.4E-53 T 28-03-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0006827|GO:0016020|GO:0033573 CNX65_RS21465 286135a2037cc90de5d0c0b82c7c0542 295 Gene3D G3DSA:1.10.287.70 89 274 0.0068 T 28-03-2018 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 Gene3D G3DSA:3.40.50.720 1 147 8.7E-26 T 28-03-2018 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 SUPERFAMILY SSF116726 132 216 8.37E-15 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 Pfam PF02254 TrkA-N domain 3 118 1.4E-26 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 Gene3D G3DSA:3.30.70.1450 148 218 1.5E-16 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 SUPERFAMILY SSF51735 1 145 9.77E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 PRINTS PR00335 TrkA potassium uptake protein signature 59 69 9.7E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 PRINTS PR00335 TrkA potassium uptake protein signature 72 86 9.7E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 9.7E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 9.7E-9 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07530 0454e934fb4c031997864d9e5c2b1dad 218 Pfam PF02080 TrkA-C domain 149 214 4.4E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 Pfam PF13377 Periplasmic binding protein-like domain 179 343 3.0E-38 T 28-03-2018 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 Gene3D G3DSA:3.40.50.2300 57 176 1.2E-24 T 28-03-2018 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 Gene3D G3DSA:1.10.260.40 18 56 3.6E-18 T 28-03-2018 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 47 4.7E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 28-03-2018 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 SUPERFAMILY SSF47413 3 48 6.75E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 SUPERFAMILY SSF53822 58 346 6.48E-69 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 Gene3D G3DSA:3.40.50.2300 177 346 1.3E-47 T 28-03-2018 CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 Gene3D G3DSA:1.10.10.10 2 17 0.017 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01780 734944d40ba39b5f43b72779f1872b49 347 SMART SM00354 1 68 4.6E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 Gene3D G3DSA:3.40.630.10 165 497 5.1E-134 T 28-03-2018 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 ProSitePatterns PS00631 Cytosol aminopeptidase signature. 341 348 - T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 SUPERFAMILY SSF52949 18 162 1.06E-27 T 28-03-2018 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 SUPERFAMILY SSF53187 175 493 2.32E-111 T 28-03-2018 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 Pfam PF00883 Cytosol aminopeptidase family, catalytic domain 182 486 2.9E-119 T 28-03-2018 IPR000819 Peptidase M17, leucyl aminopeptidase, C-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 Pfam PF02789 Cytosol aminopeptidase family, N-terminal domain 22 144 8.8E-22 T 28-03-2018 IPR008283 Peptidase M17, leucyl aminopeptidase, N-terminal GO:0004177|GO:0005622|GO:0006508 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 Gene3D G3DSA:3.40.220.10 1 164 3.9E-36 T 28-03-2018 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 PRINTS PR00481 Cytosol aminopeptidase signature 337 357 3.4E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 PRINTS PR00481 Cytosol aminopeptidase signature 365 380 3.4E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 PRINTS PR00481 Cytosol aminopeptidase signature 278 299 3.4E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 PRINTS PR00481 Cytosol aminopeptidase signature 256 273 3.4E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 PRINTS PR00481 Cytosol aminopeptidase signature 315 336 3.4E-49 T 28-03-2018 IPR011356 Peptidase M17, leucine aminopeptidase/peptidase B GO:0004177|GO:0005737|GO:0008235|GO:0019538|GO:0030145 KEGG: 00480+3.4.11.1 CNX65_RS06695 b0394dace850b1be3c831031f8c4e0dc 497 Hamap MF_00181 Probable cytosol aminopeptidase [pepA]. 5 495 34.942 T 28-03-2018 IPR023042 Peptidase M17, leucine aminopeptidase KEGG: 00480+3.4.11.1 CNX65_RS06260 0bd7b9256f57610df7d46ce75d6bdd29 288 Pfam PF01255 Putative undecaprenyl diphosphate synthase 41 261 4.9E-74 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS06260 0bd7b9256f57610df7d46ce75d6bdd29 288 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 34 262 38.678 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS06260 0bd7b9256f57610df7d46ce75d6bdd29 288 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 34 261 4.4E-75 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS06260 0bd7b9256f57610df7d46ce75d6bdd29 288 SUPERFAMILY SSF64005 34 257 2.62E-83 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS06260 0bd7b9256f57610df7d46ce75d6bdd29 288 Gene3D G3DSA:3.40.1180.10 22 264 3.2E-84 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS06260 0bd7b9256f57610df7d46ce75d6bdd29 288 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 207 224 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CNX65_RS05550 30dd93d000a78411457399fa256e5372 122 SUPERFAMILY SSF56112 4 93 4.52E-19 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS05550 30dd93d000a78411457399fa256e5372 122 Gene3D G3DSA:3.90.1200.10 1 115 4.7E-17 T 28-03-2018 CNX65_RS05550 30dd93d000a78411457399fa256e5372 122 Pfam PF01636 Phosphotransferase enzyme family 2 65 1.7E-10 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS10725 9ec2f1fe66bf04493e9e89d78d9e2aed 518 TIGRFAM TIGR01722 MMSDH: methylmalonate-semialdehyde dehydrogenase (acylating) 26 502 7.0E-214 T 28-03-2018 IPR010061 Methylmalonate-semialdehyde dehydrogenase GO:0004491|GO:0055114 KEGG: 00280+1.2.1.27|KEGG: 00410+1.2.1.18|KEGG: 00562+1.2.1.18|KEGG: 00640+1.2.1.18+1.2.1.27|MetaCyc: PWY-5642|MetaCyc: PWY-6373|Reactome: R-HSA-70895 CNX65_RS10725 9ec2f1fe66bf04493e9e89d78d9e2aed 518 Pfam PF00171 Aldehyde dehydrogenase family 34 498 2.6E-140 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS10725 9ec2f1fe66bf04493e9e89d78d9e2aed 518 Gene3D G3DSA:3.40.605.10 19 285 7.1E-84 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS10725 9ec2f1fe66bf04493e9e89d78d9e2aed 518 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 295 306 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS10725 9ec2f1fe66bf04493e9e89d78d9e2aed 518 SUPERFAMILY SSF53720 22 504 5.37E-148 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS10725 9ec2f1fe66bf04493e9e89d78d9e2aed 518 Gene3D G3DSA:3.40.309.10 286 481 2.2E-66 T 28-03-2018 CNX65_RS14830 2cee584a26e0b923ece050e9c85346fe 588 SUPERFAMILY SSF69279 35 187 3.87E-19 T 28-03-2018 CNX65_RS14830 2cee584a26e0b923ece050e9c85346fe 588 Pfam PF05954 Phage late control gene D protein (GPD) 63 345 1.0E-16 T 28-03-2018 CNX65_RS14830 2cee584a26e0b923ece050e9c85346fe 588 Gene3D G3DSA:3.55.50.10 109 198 5.0E-5 T 28-03-2018 CNX65_RS14830 2cee584a26e0b923ece050e9c85346fe 588 Gene3D G3DSA:2.40.50.260 378 484 2.0E-24 T 28-03-2018 CNX65_RS14830 2cee584a26e0b923ece050e9c85346fe 588 SUPERFAMILY SSF69255 378 458 2.88E-13 T 28-03-2018 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 Gene3D G3DSA:1.10.287.130 177 261 1.5E-6 T 28-03-2018 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 SMART SM00304 148 200 0.0022 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 Pfam PF00512 His Kinase A (phospho-acceptor) domain 203 261 3.1E-6 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 SUPERFAMILY SSF47384 184 262 5.1E-9 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 SMART SM00388 201 265 7.9E-5 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 SMART SM00387 307 408 2.2E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 SUPERFAMILY SSF55874 266 407 5.63E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 342 356 3.7E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 PRINTS PR00344 Bacterial sensor protein C-terminal signature 370 388 3.7E-6 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 310 406 9.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS31340 2e792bc4e6718abee200cc06297bf756 424 Gene3D G3DSA:3.30.565.10 266 413 1.9E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 ProSitePatterns PS00455 Putative AMP-binding domain signature. 140 151 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 SUPERFAMILY SSF56801 9 472 3.79E-100 T 28-03-2018 CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 Pfam PF00501 AMP-binding enzyme 16 382 3.6E-64 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 Pfam PF13193 AMP-binding enzyme C-terminal domain 392 466 1.0E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 Gene3D G3DSA:3.30.300.30 378 475 7.8E-20 T 28-03-2018 CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 Gene3D G3DSA:3.40.50.980 5 145 3.9E-25 T 28-03-2018 CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 Gene3D G3DSA:3.40.50.980 146 295 2.6E-26 T 28-03-2018 CNX65_RS21800 0fe7483f6bbbb6bf924c0a7cc69ec954 475 Gene3D G3DSA:2.30.38.10 296 375 4.2E-22 T 28-03-2018 CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 SUPERFAMILY SSF51735 1 242 9.94E-65 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 6.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 6.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 6.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 6.1E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 Gene3D G3DSA:3.40.50.720 1 43 6.1E-10 T 28-03-2018 CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 Gene3D G3DSA:3.40.50.720 44 246 1.5E-46 T 28-03-2018 CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 2.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 2.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 2.0E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 Pfam PF00106 short chain dehydrogenase 7 196 2.4E-48 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15315 32e5a238c29f03364ac574fa25804f90 269 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 Gene3D G3DSA:1.10.540.10 1 119 3.8E-39 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 SUPERFAMILY SSF56645 2 241 1.44E-79 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 335 354 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 216 1.4E-27 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 2.7E-34 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 PIRSF PIRSF016578 3 379 6.1E-24 T 28-03-2018 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 Gene3D G3DSA:1.20.140.10 218 381 2.8E-62 T 28-03-2018 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 Gene3D G3DSA:2.40.110.10 121 217 6.0E-37 T 28-03-2018 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 228 376 2.7E-53 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS07795 3f7a9b4f544163c74de8ab073594cccd 383 SUPERFAMILY SSF47203 226 378 1.1E-59 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS22590 79039d14c690288e67f9e3cb3fb692de 587 Pfam PF13408 Recombinase zinc beta ribbon domain 373 430 3.6E-6 T 28-03-2018 IPR025827 Recombinase zinc beta ribbon domain CNX65_RS22590 79039d14c690288e67f9e3cb3fb692de 587 Pfam PF00239 Resolvase, N terminal domain 33 178 1.0E-10 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS22590 79039d14c690288e67f9e3cb3fb692de 587 SUPERFAMILY SSF53041 32 177 1.16E-10 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS22590 79039d14c690288e67f9e3cb3fb692de 587 Pfam PF07508 Recombinase 224 348 1.3E-15 T 28-03-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 CNX65_RS22590 79039d14c690288e67f9e3cb3fb692de 587 SMART SM00857 32 186 5.6E-6 T 28-03-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 CNX65_RS22590 79039d14c690288e67f9e3cb3fb692de 587 Gene3D G3DSA:3.40.50.1390 30 195 1.7E-17 T 28-03-2018 CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 Gene3D G3DSA:1.10.357.10 64 186 7.2E-18 T 28-03-2018 CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 SUPERFAMILY SSF46689 7 88 1.04E-21 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 3.1E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 SUPERFAMILY SSF48498 83 185 1.53E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 6.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 6.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22265 8fe8940c022dfb8a3df4e1b044de95c1 200 Gene3D G3DSA:1.10.10.60 10 63 1.2E-22 T 28-03-2018 CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 SUPERFAMILY SSF47781 151 222 5.78E-25 T 28-03-2018 IPR010994 RuvA domain 2-like CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 Pfam PF10531 SLBB domain 95 147 9.7E-12 T 28-03-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 SMART SM00278 202 221 490.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 SMART SM00278 48 67 240.0 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 SMART SM00278 172 191 0.0018 T 28-03-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 Gene3D G3DSA:1.10.150.280 178 224 9.6E-18 T 28-03-2018 CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 Pfam PF12836 Helix-hairpin-helix motif 163 223 7.5E-21 T 28-03-2018 CNX65_RS05990 7f6328f861f5ae016c3583aab4d1dffc 224 Gene3D G3DSA:1.10.150.20 48 177 2.9E-12 T 28-03-2018 CNX65_RS34745 1a0ae018f817c2c7b1fad5ab010f8167 181 Gene3D G3DSA:1.10.10.10 1 97 5.6E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34745 1a0ae018f817c2c7b1fad5ab010f8167 181 Pfam PF03551 Transcriptional regulator PadR-like family 6 83 4.9E-21 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS34745 1a0ae018f817c2c7b1fad5ab010f8167 181 SUPERFAMILY SSF46785 2 171 5.34E-36 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08835 0dbc20ae857515fcfc8c4a6beab8470d 252 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS08835 0dbc20ae857515fcfc8c4a6beab8470d 252 SMART SM00382 28 242 1.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08835 0dbc20ae857515fcfc8c4a6beab8470d 252 SUPERFAMILY SSF52540 4 247 7.02E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08835 0dbc20ae857515fcfc8c4a6beab8470d 252 Pfam PF00005 ABC transporter 19 177 9.0E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS08835 0dbc20ae857515fcfc8c4a6beab8470d 252 PIRSF PIRSF039085 1 252 5.8E-116 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CNX65_RS08835 0dbc20ae857515fcfc8c4a6beab8470d 252 Gene3D G3DSA:3.40.50.300 1 252 2.3E-73 T 28-03-2018 CNX65_RS22940 ed7f8e36d38f4ea2dd51eed3aa842108 165 Gene3D G3DSA:3.30.750.24 27 132 6.2E-11 T 28-03-2018 IPR002645 STAS domain CNX65_RS22940 ed7f8e36d38f4ea2dd51eed3aa842108 165 SUPERFAMILY SSF52091 35 132 2.16E-13 T 28-03-2018 IPR002645 STAS domain CNX65_RS22940 ed7f8e36d38f4ea2dd51eed3aa842108 165 Pfam PF13466 STAS domain 43 120 3.1E-8 T 28-03-2018 IPR002645 STAS domain CNX65_RS10670 f0b602d5accb6dcea29f902d90295ac7 375 Gene3D G3DSA:3.40.50.2000 180 346 2.2E-38 T 28-03-2018 CNX65_RS10670 f0b602d5accb6dcea29f902d90295ac7 375 Pfam PF13439 Glycosyltransferase Family 4 14 173 3.6E-30 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS10670 f0b602d5accb6dcea29f902d90295ac7 375 Pfam PF13692 Glycosyl transferases group 1 190 328 5.5E-26 T 28-03-2018 CNX65_RS10670 f0b602d5accb6dcea29f902d90295ac7 375 Gene3D G3DSA:3.40.50.2000 2 179 1.7E-16 T 28-03-2018 CNX65_RS10670 f0b602d5accb6dcea29f902d90295ac7 375 SUPERFAMILY SSF53756 4 363 1.41E-77 T 28-03-2018 CNX65_RS10610 95a6fbed90ba0a7df05afc4bcf97a2b0 233 Pfam PF07722 Peptidase C26 8 212 4.5E-56 T 28-03-2018 IPR011697 Peptidase C26 GO:0016787 Reactome: R-HSA-6798695 CNX65_RS10610 95a6fbed90ba0a7df05afc4bcf97a2b0 233 SUPERFAMILY SSF52317 31 228 3.06E-35 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS10610 95a6fbed90ba0a7df05afc4bcf97a2b0 233 Gene3D G3DSA:3.40.50.880 4 233 6.1E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS11505 9605f95cab7c3b45361e385b3d8a7167 248 SUPERFAMILY SSF56752 17 233 1.44E-31 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CNX65_RS11505 9605f95cab7c3b45361e385b3d8a7167 248 Gene3D G3DSA:3.30.470.10 6 97 7.5E-11 T 28-03-2018 CNX65_RS11505 9605f95cab7c3b45361e385b3d8a7167 248 Pfam PF01063 Amino-transferase class IV 24 220 1.7E-21 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CNX65_RS11505 9605f95cab7c3b45361e385b3d8a7167 248 Gene3D G3DSA:3.20.10.10 106 243 4.1E-21 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF58104 763 886 3.14E-11 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF55874 1144 1313 4.98E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00448 1356 1470 1.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00388 1087 1155 9.1E-22 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF52172 1347 1475 6.97E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF55781 874 1042 7.85E-31 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1238 1252 3.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1256 1266 3.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1273 1291 3.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 1297 1310 3.4E-15 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:3.30.565.10 1159 1318 3.4E-49 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF58104 395 575 9.29E-14 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF58104 303 394 3.14E-7 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Pfam PF00672 HAMP domain 378 422 2.0E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Pfam PF00672 HAMP domain 102 147 3.9E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 375 427 1.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 743 795 4.4E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 467 519 9.6E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 835 887 1.4E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 6 58 50.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 651 703 9.8E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 99 151 8.7E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 283 335 2.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 559 611 1.0E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00304 191 243 2.0E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:1.10.287.130 1087 1151 3.8E-16 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:3.30.450.40 883 1086 1.1E-28 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 1202 1312 9.2E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 479 569 1.3E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 570 661 3.6E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 203 294 6.9E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 846 882 0.11 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 662 754 1.6E-21 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 755 845 2.6E-23 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 295 386 2.5E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 75 202 3.3E-18 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:2.60.120.260 387 478 1.8E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF58104 119 295 2.62E-11 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00065 911 1054 3.3E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Pfam PF13185 GAF domain 910 1042 1.1E-19 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Pfam PF00512 His Kinase A (phospho-acceptor) domain 1088 1155 3.9E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF58104 579 759 1.33E-12 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SMART SM00387 1202 1313 8.1E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Gene3D G3DSA:3.40.50.2300 1354 1478 4.0E-31 T 28-03-2018 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 SUPERFAMILY SSF47384 1073 1156 2.16E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS25300 2e024109f2695a055bad46db13ad1055 1479 Pfam PF00072 Response regulator receiver domain 1358 1470 1.3E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS21730 6a0a88f6e737f2cbb046b3f48bf6e94d 434 SUPERFAMILY SSF51905 283 383 2.06E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21730 6a0a88f6e737f2cbb046b3f48bf6e94d 434 SUPERFAMILY SSF51905 18 183 2.06E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21730 6a0a88f6e737f2cbb046b3f48bf6e94d 434 Pfam PF01494 FAD binding domain 126 331 1.7E-12 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS21730 6a0a88f6e737f2cbb046b3f48bf6e94d 434 Gene3D G3DSA:3.50.50.60 12 383 1.8E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21730 6a0a88f6e737f2cbb046b3f48bf6e94d 434 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 18 40 1.9E-11 T 28-03-2018 CNX65_RS21730 6a0a88f6e737f2cbb046b3f48bf6e94d 434 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 1.9E-11 T 28-03-2018 CNX65_RS21730 6a0a88f6e737f2cbb046b3f48bf6e94d 434 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 1.9E-11 T 28-03-2018 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 192 1.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 192 204 1.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 162 176 1.8E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 SMART SM00421 159 216 1.0E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 216 3.3E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 Gene3D G3DSA:3.40.50.2300 4 132 3.6E-40 T 28-03-2018 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 SUPERFAMILY SSF46894 150 222 1.02E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 ProSitePatterns PS00622 LuxR-type HTH domain signature. 176 203 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 SUPERFAMILY SSF52172 4 139 1.57E-34 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 Pfam PF00072 Response regulator receiver domain 7 122 1.7E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 SMART SM00448 5 121 4.8E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS13890 917ce6e15165ef58632f2a3f002bed27 227 Gene3D G3DSA:1.10.10.10 133 225 4.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27850 5754690ccbaa7d4b3ec0be3babc5b059 630 Pfam PF04542 Sigma-70 region 2 26 91 7.1E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27850 5754690ccbaa7d4b3ec0be3babc5b059 630 Gene3D G3DSA:1.10.1740.10 2 181 1.5E-21 T 28-03-2018 CNX65_RS27850 5754690ccbaa7d4b3ec0be3babc5b059 630 Gene3D G3DSA:3.20.20.80 454 627 5.1E-15 T 28-03-2018 CNX65_RS27850 5754690ccbaa7d4b3ec0be3babc5b059 630 SUPERFAMILY SSF51445 411 627 3.59E-23 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS27850 5754690ccbaa7d4b3ec0be3babc5b059 630 SUPERFAMILY SSF88946 10 97 5.02E-19 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27850 5754690ccbaa7d4b3ec0be3babc5b059 630 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 181 8.3E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS27850 5754690ccbaa7d4b3ec0be3babc5b059 630 Pfam PF11790 Glycosyl hydrolase catalytic core 411 626 1.1E-51 T 28-03-2018 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 Pfam PF01145 SPFH domain / Band 7 family 4 172 2.4E-23 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 SUPERFAMILY SSF117892 34 161 7.59E-20 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 PRINTS PR00721 Stomatin signature 132 150 1.4E-17 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 PRINTS PR00721 Stomatin signature 176 199 1.4E-17 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 PRINTS PR00721 Stomatin signature 7 29 1.4E-17 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 PRINTS PR00721 Stomatin signature 53 74 1.4E-17 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 PRINTS PR00721 Stomatin signature 151 172 1.4E-17 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS07555 8e67ab8cddfb9826f8c72e436b350e4d 234 SMART SM00244 3 156 0.004 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS07445 8c670d457f95451183f7e10c4c5a954f 378 SUPERFAMILY SSF53822 46 351 1.99E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS07445 8c670d457f95451183f7e10c4c5a954f 378 Gene3D G3DSA:3.40.50.2300 155 363 1.2E-34 T 28-03-2018 CNX65_RS07445 8c670d457f95451183f7e10c4c5a954f 378 Gene3D G3DSA:3.40.50.2300 44 154 2.1E-14 T 28-03-2018 CNX65_RS07445 8c670d457f95451183f7e10c4c5a954f 378 Pfam PF13407 Periplasmic binding protein domain 50 313 2.1E-53 T 28-03-2018 IPR025997 Periplasmic binding protein CNX65_RS09540 c532fe61b2703688399318df8b9a78bc 95 Gene3D G3DSA:3.30.70.100 3 50 0.0057 T 28-03-2018 CNX65_RS09540 c532fe61b2703688399318df8b9a78bc 95 Pfam PF04972 BON domain 3 59 3.3E-6 T 28-03-2018 IPR007055 BON domain CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 Pfam PF13288 DXP reductoisomerase C-terminal domain 274 391 1.4E-31 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 7 396 42.816 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 Gene3D G3DSA:3.40.50.720 4 162 2.2E-45 T 28-03-2018 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 158 241 5.8E-37 T 28-03-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 SUPERFAMILY SSF55347 140 276 1.05E-54 T 28-03-2018 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 PIRSF PIRSF006205 4 403 2.6E-134 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 SUPERFAMILY SSF51735 4 162 8.53E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 6 399 2.9E-111 T 28-03-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 7 146 3.5E-35 T 28-03-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 Gene3D G3DSA:1.10.1740.10 315 398 2.0E-26 T 28-03-2018 CNX65_RS28900 2fa3b3e20654b074b0e8017a019e8e62 406 SUPERFAMILY SSF69055 305 397 3.53E-24 T 28-03-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00630+1.1.1.26|KEGG: 00900+1.1.1.267|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7560 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 SUPERFAMILY SSF53748 34 377 3.27E-40 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 Gene3D G3DSA:3.40.50.1260 187 366 3.4E-17 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 Pfam PF00162 Phosphoglycerate kinase 35 366 5.9E-36 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 Gene3D G3DSA:3.40.50.1260 27 178 6.1E-23 T 28-03-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 PRINTS PR00477 Phosphoglycerate kinase family signature 189 208 3.0E-11 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 PRINTS PR00477 Phosphoglycerate kinase family signature 107 122 3.0E-11 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 PRINTS PR00477 Phosphoglycerate kinase family signature 135 157 3.0E-11 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS16880 40e4b23dcff7d289fba9422f193e9bd3 388 PRINTS PR00477 Phosphoglycerate kinase family signature 354 371 3.0E-11 T 28-03-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 Gene3D G3DSA:3.40.50.300 1 167 4.2E-36 T 28-03-2018 CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 189 8.1E-19 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 262 442 1.7E-25 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 Hamap MF_00027 Cobyrinate a,c-diamide synthase [cbiA]. 1 447 42.057 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 4 455 3.2E-115 T 28-03-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 SUPERFAMILY SSF52317 260 454 1.53E-29 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 Gene3D G3DSA:3.40.50.880 168 406 1.8E-27 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS28745 af47226447e9dc9f4a76f27639db5914 465 SUPERFAMILY SSF52540 3 196 2.09E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 327 336 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 Gene3D G3DSA:1.10.630.10 1 384 3.2E-77 T 28-03-2018 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00385 P450 superfamily signature 223 240 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00385 P450 superfamily signature 258 269 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00385 P450 superfamily signature 334 345 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00385 P450 superfamily signature 325 334 1.1E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 SUPERFAMILY SSF48264 5 384 7.86E-99 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 127 143 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 181 203 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 304 319 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 258 269 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 334 345 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 144 159 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 325 334 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 276 303 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 PRINTS PR00359 B-class P450 signature 80 91 1.4E-55 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 Pfam PF00067 Cytochrome P450 203 355 1.3E-19 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS09790 62b383e8360387b86b7f0ae803185a7c 384 Pfam PF00067 Cytochrome P450 31 156 2.1E-7 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13320 16c1cb5b3438556e0309e0320dfeee46 381 SUPERFAMILY SSF53850 69 279 3.5E-16 T 28-03-2018 CNX65_RS13320 16c1cb5b3438556e0309e0320dfeee46 381 Pfam PF09084 NMT1/THI5 like 79 281 6.0E-27 T 28-03-2018 IPR015168 SsuA/THI5-like CNX65_RS13320 16c1cb5b3438556e0309e0320dfeee46 381 Gene3D G3DSA:3.40.190.10 187 370 1.4E-17 T 28-03-2018 CNX65_RS13320 16c1cb5b3438556e0309e0320dfeee46 381 Gene3D G3DSA:3.40.190.10 67 186 9.5E-5 T 28-03-2018 CNX65_RS27375 420cb3c3268816b20d440744d1d52205 214 Gene3D G3DSA:3.40.630.30 1 205 2.8E-39 T 28-03-2018 CNX65_RS27375 420cb3c3268816b20d440744d1d52205 214 SUPERFAMILY SSF55729 1 186 4.71E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS27375 420cb3c3268816b20d440744d1d52205 214 Pfam PF00583 Acetyltransferase (GNAT) family 49 183 4.5E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS18675 f08b6b68c805de0315ef281775038e6e 411 Pfam PF07005 Putative sugar-binding N-terminal domain 4 227 1.4E-62 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CNX65_RS18675 f08b6b68c805de0315ef281775038e6e 411 SUPERFAMILY SSF142764 4 410 3.14E-102 T 28-03-2018 CNX65_RS18675 f08b6b68c805de0315ef281775038e6e 411 Pfam PF17042 Putative nucleotide-binding of sugar-metabolising enzyme 247 403 7.5E-35 T 28-03-2018 IPR031475 Putative nucleotide-binding C-terminal domain CNX65_RS18675 f08b6b68c805de0315ef281775038e6e 411 Gene3D G3DSA:3.40.50.10840 3 236 1.7E-66 T 28-03-2018 IPR010737 Putative sugar-binding, N-terminal domain CNX65_RS33350 8b0e3164a3a6a1cf0ea04920e4e73821 360 SUPERFAMILY SSF102405 233 353 5.49E-27 T 28-03-2018 CNX65_RS33350 8b0e3164a3a6a1cf0ea04920e4e73821 360 SUPERFAMILY SSF102405 133 196 5.49E-27 T 28-03-2018 CNX65_RS33350 8b0e3164a3a6a1cf0ea04920e4e73821 360 Gene3D G3DSA:3.40.50.450 127 359 6.8E-49 T 28-03-2018 CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Gene3D G3DSA:2.60.40.10 651 783 2.2E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Gene3D G3DSA:2.60.40.10 804 928 4.2E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Gene3D G3DSA:2.140.10.30 65 177 1.1E-10 T 28-03-2018 CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 SUPERFAMILY SSF82171 326 616 1.22E-29 T 28-03-2018 CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 SUPERFAMILY SSF82171 123 267 1.22E-29 T 28-03-2018 CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Pfam PF07676 WD40-like Beta Propeller Repeat 425 446 2.3E-4 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Pfam PF07676 WD40-like Beta Propeller Repeat 153 181 6.1E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Pfam PF07676 WD40-like Beta Propeller Repeat 377 402 0.012 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Pfam PF07676 WD40-like Beta Propeller Repeat 478 497 0.0012 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Gene3D G3DSA:2.130.10.150 178 344 2.7E-14 T 28-03-2018 CNX65_RS14775 9984ed1d31a005f43242334659254634 1024 Gene3D G3DSA:2.130.10.150 373 617 8.6E-22 T 28-03-2018 CNX65_RS21250 06c9ce03634c61aa46c436384e4ab7ca 422 Gene3D G3DSA:3.40.190.10 166 345 1.8E-25 T 28-03-2018 CNX65_RS21250 06c9ce03634c61aa46c436384e4ab7ca 422 SUPERFAMILY SSF53850 44 412 4.0E-59 T 28-03-2018 CNX65_RS21250 06c9ce03634c61aa46c436384e4ab7ca 422 Gene3D G3DSA:3.40.190.10 9 165 3.0E-24 T 28-03-2018 CNX65_RS21250 06c9ce03634c61aa46c436384e4ab7ca 422 Pfam PF01547 Bacterial extracellular solute-binding protein 54 324 1.2E-31 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS02270 560239689bbfa818d7c721485d36d87e 303 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 289 1.8E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02270 560239689bbfa818d7c721485d36d87e 303 SUPERFAMILY SSF161098 59 289 1.96E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02270 560239689bbfa818d7c721485d36d87e 303 Gene3D G3DSA:1.10.3720.10 2 294 2.9E-41 T 28-03-2018 CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 SUPERFAMILY SSF90123 6 312 1.44E-70 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 ProSitePatterns PS00211 ABC transporters family signature. 472 486 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 SUPERFAMILY SSF52540 325 570 2.83E-79 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 Pfam PF00005 ABC transporter 351 499 5.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 Pfam PF00664 ABC transporter transmembrane region 18 288 2.0E-46 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 Gene3D G3DSA:1.20.1560.10 1 315 3.3E-69 T 28-03-2018 CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 Gene3D G3DSA:3.40.50.300 324 576 2.2E-62 T 28-03-2018 CNX65_RS18805 da2c0a296fef361adad839b48d06a9a1 577 SMART SM00382 360 546 5.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS24385 814b1457b14281b2d8b4e7bc05aaf3ec 296 Pfam PF01828 Peptidase A4 family 72 257 5.0E-26 T 28-03-2018 IPR000250 Peptidase G1 GO:0004190|GO:0006508 CNX65_RS24385 814b1457b14281b2d8b4e7bc05aaf3ec 296 SUPERFAMILY SSF49899 70 275 2.14E-27 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS12035 4ecc34552543aeb469e516a42aa3ad86 294 Gene3D G3DSA:3.40.50.720 1 166 7.7E-22 T 28-03-2018 CNX65_RS12035 4ecc34552543aeb469e516a42aa3ad86 294 Pfam PF05368 NmrA-like family 9 236 8.6E-51 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CNX65_RS12035 4ecc34552543aeb469e516a42aa3ad86 294 SUPERFAMILY SSF51735 6 261 2.52E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS25235 130b9b96d052976c1c9590622a6d7b2c 210 SUPERFAMILY SSF53597 3 191 5.5E-23 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS25235 130b9b96d052976c1c9590622a6d7b2c 210 Pfam PF01872 RibD C-terminal domain 4 181 4.1E-22 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS25235 130b9b96d052976c1c9590622a6d7b2c 210 Gene3D G3DSA:3.40.430.10 3 193 5.4E-31 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS19925 1be3c724f0101483d1da3b8b9607d93b 235 Pfam PF00925 GTP cyclohydrolase II 23 190 3.1E-59 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS19925 1be3c724f0101483d1da3b8b9607d93b 235 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 13 216 34.825 T 28-03-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS19925 1be3c724f0101483d1da3b8b9607d93b 235 SUPERFAMILY SSF142695 14 191 2.09E-53 T 28-03-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539 CNX65_RS06705 41655ed37f6990f5b45f8f44cecff858 367 PIRSF PIRSF006468 7 367 2.0E-130 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CNX65_RS06705 41655ed37f6990f5b45f8f44cecff858 367 TIGRFAM TIGR01123 ilvE_II: branched-chain amino acid aminotransferase 49 366 1.6E-135 T 28-03-2018 IPR005786 Branched-chain amino acid aminotransferase II GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767|Reactome: R-HSA-70895 CNX65_RS06705 41655ed37f6990f5b45f8f44cecff858 367 Pfam PF01063 Amino-transferase class IV 75 321 1.2E-29 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CNX65_RS06705 41655ed37f6990f5b45f8f44cecff858 367 SUPERFAMILY SSF56752 18 363 1.83E-111 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CNX65_RS06705 41655ed37f6990f5b45f8f44cecff858 367 Gene3D G3DSA:3.30.470.10 3 187 4.0E-64 T 28-03-2018 CNX65_RS06705 41655ed37f6990f5b45f8f44cecff858 367 Gene3D G3DSA:3.20.10.10 188 362 4.3E-51 T 28-03-2018 CNX65_RS06705 41655ed37f6990f5b45f8f44cecff858 367 ProSitePatterns PS00770 Aminotransferases class-IV signature. 239 272 - T 28-03-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824|GO:0008152 Reactome: R-HSA-70895 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 SUPERFAMILY SSF56024 266 412 2.22E-21 T 28-03-2018 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 Pfam PF00614 Phospholipase D Active site motif 161 181 8.3E-8 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 Pfam PF13091 PLD-like domain 275 400 5.8E-10 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 SUPERFAMILY SSF56024 47 255 5.49E-34 T 28-03-2018 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 SMART SM00155 157 184 0.084 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 SMART SM00155 355 382 0.0057 T 28-03-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 Gene3D G3DSA:3.30.870.10 44 244 6.2E-29 T 28-03-2018 CNX65_RS04985 6b6fead8d95dd3b280ad8d9fa11348ca 470 Gene3D G3DSA:3.30.870.10 245 417 1.6E-25 T 28-03-2018 CNX65_RS30050 63581d52376651a8a7cebadf13d5617b 176 Gene3D G3DSA:3.40.630.30 4 176 2.0E-25 T 28-03-2018 CNX65_RS30050 63581d52376651a8a7cebadf13d5617b 176 SUPERFAMILY SSF55729 12 158 6.53E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS30050 63581d52376651a8a7cebadf13d5617b 176 Pfam PF13302 Acetyltransferase (GNAT) domain 16 155 1.0E-25 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 Gene3D G3DSA:3.30.70.100 318 372 1.7E-6 T 28-03-2018 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 SUPERFAMILY SSF143597 19 142 3.79E-16 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 Gene3D G3DSA:3.40.1700.10 10 143 1.1E-15 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 Gene3D G3DSA:1.10.150.200 373 427 7.6E-7 T 28-03-2018 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 25 138 1.9E-16 T 28-03-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 Pfam PF13424 Tetratricopeptide repeat 419 487 3.1E-9 T 28-03-2018 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 Gene3D G3DSA:1.25.40.10 428 546 1.7E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 SUPERFAMILY SSF48452 320 528 2.66E-23 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 SMART SM00028 417 450 360.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 SMART SM00028 377 410 13.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 SMART SM00028 337 370 140.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 SMART SM00028 457 490 10.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS20940 5743059d912cb439264dd4de5b122a9d 547 SMART SM00028 497 530 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS18745 56e8d8c3f3ea4c1d890263c39733879f 199 SUPERFAMILY SSF160104 3 191 1.44E-27 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CNX65_RS18745 56e8d8c3f3ea4c1d890263c39733879f 199 Pfam PF06314 Acetoacetate decarboxylase (ADC) 27 114 9.8E-13 T 28-03-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CNX65_RS18745 56e8d8c3f3ea4c1d890263c39733879f 199 Gene3D G3DSA:2.40.400.10 2 144 3.9E-20 T 28-03-2018 IPR023375 Acetoacetate decarboxylase beta barrel domain KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 CNX65_RS02545 9e7a8a4e44d5ca9097a03a0e57654990 533 Gene3D G3DSA:2.70.98.10 444 518 4.0E-8 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS02545 9e7a8a4e44d5ca9097a03a0e57654990 533 Gene3D G3DSA:1.50.10.100 21 276 1.1E-48 T 28-03-2018 CNX65_RS02545 9e7a8a4e44d5ca9097a03a0e57654990 533 SUPERFAMILY SSF48230 25 290 7.85E-51 T 28-03-2018 IPR008929 Chondroitin AC/alginate lyase Reactome: R-HSA-2022923 CNX65_RS02545 9e7a8a4e44d5ca9097a03a0e57654990 533 Pfam PF08124 Polysaccharide lyase family 8, N terminal alpha-helical domain 63 253 8.4E-24 T 28-03-2018 IPR012970 Polysaccharide lyase 8, N-terminal alpha-helical CNX65_RS02545 9e7a8a4e44d5ca9097a03a0e57654990 533 SUPERFAMILY SSF74650 280 512 1.78E-51 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CNX65_RS02545 9e7a8a4e44d5ca9097a03a0e57654990 533 Pfam PF02278 Polysaccharide lyase family 8, super-sandwich domain 283 502 1.7E-47 T 28-03-2018 IPR003159 Polysaccharide lyase family 8, central domain GO:0005576|GO:0016829 CNX65_RS02545 9e7a8a4e44d5ca9097a03a0e57654990 533 Gene3D G3DSA:2.70.98.10 279 443 2.7E-44 T 28-03-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 CNX65_RS35045 06d26c3ca6fde1341f841c85ec9ca341 290 SUPERFAMILY SSF52540 30 281 7.66E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS35045 06d26c3ca6fde1341f841c85ec9ca341 290 Pfam PF13614 AAA domain 30 209 2.6E-59 T 28-03-2018 IPR025669 AAA domain CNX65_RS35045 06d26c3ca6fde1341f841c85ec9ca341 290 Gene3D G3DSA:3.40.50.300 29 287 5.9E-60 T 28-03-2018 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 PRINTS PR00773 GrpE protein signature 153 168 4.6E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 PRINTS PR00773 GrpE protein signature 180 199 4.6E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 PRINTS PR00773 GrpE protein signature 78 94 4.6E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 PRINTS PR00773 GrpE protein signature 106 121 4.6E-24 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 SUPERFAMILY SSF58014 63 144 1.12E-16 T 28-03-2018 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 Gene3D G3DSA:3.90.20.20 49 144 2.9E-16 T 28-03-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 Pfam PF01025 GrpE 62 200 7.0E-33 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 SUPERFAMILY SSF51064 147 201 3.66E-16 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 Hamap MF_01151 Protein GrpE [grpE]. 6 201 17.017 T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 ProSitePatterns PS01071 grpE protein signature. 156 199 - T 28-03-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 CNX65_RS34330 48482396b05cc8ddb9297039666d9f62 218 Gene3D G3DSA:2.30.22.10 145 207 2.3E-21 T 28-03-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 Gene3D G3DSA:3.40.50.300 349 541 7.4E-35 T 28-03-2018 CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 Pfam PF00005 ABC transporter 364 492 5.8E-15 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 Pfam PF00005 ABC transporter 22 184 2.5E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 Gene3D G3DSA:3.40.50.300 1 334 5.5E-48 T 28-03-2018 CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 SUPERFAMILY SSF52540 5 237 9.01E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 SMART SM00382 371 538 5.0E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 SMART SM00382 29 229 8.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 SUPERFAMILY SSF52540 362 539 6.1E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS05300 300fcacd67199d3e73c9cf92aa113b82 542 Pfam PF12848 ABC transporter 226 330 6.4E-6 T 28-03-2018 IPR032781 ABC-transporter extension domain CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 PIRSF PIRSF000171 1 575 9.9E-45 T 28-03-2018 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 SUPERFAMILY SSF46977 446 583 1.44E-47 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 7 583 5.7E-251 T 28-03-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 SUPERFAMILY SSF56425 236 354 2.99E-40 T 28-03-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 Pfam PF02910 Fumarate reductase flavoprotein C-term 454 583 1.4E-44 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 Gene3D G3DSA:4.10.80.40 536 583 1.2E-18 T 28-03-2018 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 SUPERFAMILY SSF51905 2 259 1.18E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 SUPERFAMILY SSF51905 358 429 1.18E-73 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 378 385 1.3E-5 T 28-03-2018 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 1.3E-5 T 28-03-2018 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 Pfam PF00890 FAD binding domain 7 400 2.3E-113 T 28-03-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 TIGRFAM TIGR01816 sdhA_forward: succinate dehydrogenase, flavoprotein subunit 4 583 1.4E-281 T 28-03-2018 IPR011281 Succinate dehydrogenase, flavoprotein subunit GO:0006099|GO:0016627|GO:0050660|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 Gene3D G3DSA:3.50.50.60 304 416 1.3E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 40 49 - T 28-03-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 Gene3D G3DSA:1.20.58.100 425 535 5.4E-33 T 28-03-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31715 843fcc7930acd11ca81be0f9f4f7089b 583 Gene3D G3DSA:3.50.50.60 3 303 1.5E-46 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS16560 8f3a8c11173302695f768681836116c6 486 SMART SM00637 41 140 1.6E-47 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16560 8f3a8c11173302695f768681836116c6 486 Gene3D G3DSA:2.115.10.20 153 481 3.2E-53 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16560 8f3a8c11173302695f768681836116c6 486 SUPERFAMILY SSF75005 195 477 5.14E-24 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16560 8f3a8c11173302695f768681836116c6 486 Pfam PF00553 Cellulose binding domain 41 140 5.0E-33 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS16560 8f3a8c11173302695f768681836116c6 486 Gene3D G3DSA:2.60.40.290 32 140 5.8E-37 T 28-03-2018 CNX65_RS16560 8f3a8c11173302695f768681836116c6 486 Pfam PF03664 Glycosyl hydrolase family 62 168 452 4.5E-61 T 28-03-2018 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS16560 8f3a8c11173302695f768681836116c6 486 SUPERFAMILY SSF49384 37 142 1.19E-32 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS35075 66a23e0decc5ab5210453a8bde542684 114 Gene3D G3DSA:3.30.230.10 1 114 2.4E-30 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS35075 66a23e0decc5ab5210453a8bde542684 114 SUPERFAMILY SSF54211 2 113 1.92E-20 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS35075 66a23e0decc5ab5210453a8bde542684 114 Pfam PF00825 Ribonuclease P 2 112 3.3E-25 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CNX65_RS35075 66a23e0decc5ab5210453a8bde542684 114 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 2 111 13.849 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CNX65_RS35075 66a23e0decc5ab5210453a8bde542684 114 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 7 111 1.2E-14 T 28-03-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 CNX65_RS14295 1d11f376b9b74aaa8522ee786693a9e8 315 SUPERFAMILY SSF161098 76 303 8.5E-53 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14295 1d11f376b9b74aaa8522ee786693a9e8 315 Gene3D G3DSA:1.10.3720.10 35 315 7.6E-40 T 28-03-2018 CNX65_RS14295 1d11f376b9b74aaa8522ee786693a9e8 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 303 3.8E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS33910 c21662f4715e9fa4c6701824875b8f28 247 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 16 132 1.2E-9 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS33910 c21662f4715e9fa4c6701824875b8f28 247 Gene3D G3DSA:1.20.120.450 4 139 1.2E-6 T 28-03-2018 CNX65_RS33910 c21662f4715e9fa4c6701824875b8f28 247 SUPERFAMILY SSF109854 7 129 1.12E-5 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS33910 c21662f4715e9fa4c6701824875b8f28 247 Pfam PF07398 MDMPI C-terminal domain 149 241 5.4E-8 T 28-03-2018 IPR010872 MDMPI C-terminal CNX65_RS22425 80668a132752a82cc838426066764aea 427 SUPERFAMILY SSF52777 20 181 2.59E-39 T 28-03-2018 CNX65_RS22425 80668a132752a82cc838426066764aea 427 Gene3D G3DSA:3.30.559.10 2 194 5.3E-37 T 28-03-2018 CNX65_RS22425 80668a132752a82cc838426066764aea 427 SUPERFAMILY SSF52777 190 424 8.45E-56 T 28-03-2018 CNX65_RS22425 80668a132752a82cc838426066764aea 427 Pfam PF00668 Condensation domain 10 423 1.3E-74 T 28-03-2018 IPR001242 Condensation domain CNX65_RS05910 4fe01effb421c062a829eec6cf267569 971 Pfam PF10150 Ribonuclease E/G family 427 698 3.5E-104 T 28-03-2018 IPR019307 RNA-binding protein AU-1/Ribonuclease E/G GO:0003723 CNX65_RS05910 4fe01effb421c062a829eec6cf267569 971 SUPERFAMILY SSF50249 348 431 4.52E-16 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS05910 4fe01effb421c062a829eec6cf267569 971 Gene3D G3DSA:3.30.56.50 30 72 2.4E-8 T 28-03-2018 CNX65_RS05910 4fe01effb421c062a829eec6cf267569 971 SMART SM00316 346 425 1.5E-6 T 28-03-2018 IPR022967 RNA-binding domain, S1 CNX65_RS05910 4fe01effb421c062a829eec6cf267569 971 TIGRFAM TIGR00757 RNaseEG: ribonuclease, Rne/Rng family 323 727 6.0E-152 T 28-03-2018 IPR004659 Ribonuclease E/G GO:0003723|GO:0004540|GO:0006396 CNX65_RS05910 4fe01effb421c062a829eec6cf267569 971 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 27 76 2.1E-10 T 28-03-2018 IPR006847 Translation initiation factor IF-2, N-terminal CNX65_RS05910 4fe01effb421c062a829eec6cf267569 971 Gene3D G3DSA:2.40.50.140 342 430 1.3E-26 T 28-03-2018 CNX65_RS30485 69b8ab7e0921f89dcccb55f533653b6f 352 Gene3D G3DSA:3.50.50.60 2 72 6.2E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30485 69b8ab7e0921f89dcccb55f533653b6f 352 Pfam PF01266 FAD dependent oxidoreductase 5 335 7.5E-49 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS30485 69b8ab7e0921f89dcccb55f533653b6f 352 SUPERFAMILY SSF54373 207 299 8.63E-15 T 28-03-2018 CNX65_RS30485 69b8ab7e0921f89dcccb55f533653b6f 352 Gene3D G3DSA:3.30.9.10 73 299 8.2E-35 T 28-03-2018 CNX65_RS30485 69b8ab7e0921f89dcccb55f533653b6f 352 SUPERFAMILY SSF51905 299 344 1.1E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30485 69b8ab7e0921f89dcccb55f533653b6f 352 SUPERFAMILY SSF51905 4 206 1.1E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19200 5e343b875ce8bcd1b2e5106785071178 346 SUPERFAMILY SSF53686 20 319 2.23E-51 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS19200 5e343b875ce8bcd1b2e5106785071178 346 Gene3D G3DSA:3.40.50.1100 32 130 1.5E-13 T 28-03-2018 CNX65_RS19200 5e343b875ce8bcd1b2e5106785071178 346 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 19 301 4.1E-32 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS19200 5e343b875ce8bcd1b2e5106785071178 346 Gene3D G3DSA:3.40.50.1100 131 315 3.0E-35 T 28-03-2018 CNX65_RS23270 d21549ceab483741430f13ecd0a11f58 126 Gene3D G3DSA:3.10.180.10 1 125 6.7E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS23270 d21549ceab483741430f13ecd0a11f58 126 SUPERFAMILY SSF54593 4 121 3.24E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 130 158 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 SUPERFAMILY SSF51735 6 218 8.78E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 Gene3D G3DSA:3.40.50.720 1 172 1.6E-49 T 28-03-2018 CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 9.0E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 143 162 9.0E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 143 162 8.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 117 133 8.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 8.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 162 179 8.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 8.9E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 Pfam PF00106 short chain dehydrogenase 6 186 6.2E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 Gene3D G3DSA:3.40.50.720 173 223 8.0E-4 T 28-03-2018 CNX65_RS34710 e9d3979eefe5fc75c166813a9082c183 229 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 177 0.0016 T 28-03-2018 CNX65_RS08800 7caca38f876849d9f7cb8a6ac09b0edf 196 Gene3D G3DSA:3.10.180.10 45 190 3.8E-28 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS08800 7caca38f876849d9f7cb8a6ac09b0edf 196 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 50 170 1.2E-15 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS08800 7caca38f876849d9f7cb8a6ac09b0edf 196 SUPERFAMILY SSF54593 47 174 2.28E-29 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS29080 123104ae17a3fd78d5f4499247594777 145 Pfam PF00886 Ribosomal protein S16 9 67 6.0E-23 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29080 123104ae17a3fd78d5f4499247594777 145 Gene3D G3DSA:3.30.1320.10 2 85 4.0E-30 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29080 123104ae17a3fd78d5f4499247594777 145 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 4.3E-30 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29080 123104ae17a3fd78d5f4499247594777 145 SUPERFAMILY SSF54565 2 95 1.83E-32 T 28-03-2018 IPR023803 Ribosomal protein S16 domain Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29080 123104ae17a3fd78d5f4499247594777 145 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 22.989 T 28-03-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS01350 225a30c8c867a3e304381e6f43b1de22 68 Pfam PF16827 zinc-finger 2 60 3.9E-15 T 28-03-2018 IPR031795 Putative zinc-finger containing protein CNX65_RS34820 62798bc2a731ef24ab9f1fa8e20697c6 278 SUPERFAMILY SSF47413 30 77 1.2E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS34820 62798bc2a731ef24ab9f1fa8e20697c6 278 Gene3D G3DSA:1.10.260.40 1 81 1.8E-14 T 28-03-2018 CNX65_RS34820 62798bc2a731ef24ab9f1fa8e20697c6 278 Pfam PF13560 Helix-turn-helix domain 5 84 1.1E-18 T 28-03-2018 CNX65_RS34820 62798bc2a731ef24ab9f1fa8e20697c6 278 SMART SM00530 9 81 4.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS22810 4f51cff846c2cb624c023deee68dbe0b 402 SUPERFAMILY SSF53448 67 221 6.38E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS22810 4f51cff846c2cb624c023deee68dbe0b 402 SUPERFAMILY SSF53448 283 350 6.38E-26 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS22810 4f51cff846c2cb624c023deee68dbe0b 402 Pfam PF00535 Glycosyl transferase family 2 75 198 2.2E-11 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS22810 4f51cff846c2cb624c023deee68dbe0b 402 Gene3D G3DSA:3.90.550.10 48 392 7.7E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS33690 daa6ba0c2c79abf85e68ba096ae214bb 285 Gene3D G3DSA:1.25.40.10 7 86 7.8E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS33690 daa6ba0c2c79abf85e68ba096ae214bb 285 SMART SM00267 81 260 4.1E-42 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS33690 daa6ba0c2c79abf85e68ba096ae214bb 285 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 90 259 4.3E-40 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS33690 daa6ba0c2c79abf85e68ba096ae214bb 285 SUPERFAMILY SSF55073 97 259 5.89E-39 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS33690 daa6ba0c2c79abf85e68ba096ae214bb 285 Gene3D G3DSA:3.30.70.270 87 261 2.7E-47 T 28-03-2018 CNX65_RS33690 daa6ba0c2c79abf85e68ba096ae214bb 285 Pfam PF00990 Diguanylate cyclase, GGDEF domain 93 255 2.3E-34 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS16765 f5a652fe4687d7685980a019e091104a 172 Pfam PF12680 SnoaL-like domain 10 133 4.5E-13 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS16765 f5a652fe4687d7685980a019e091104a 172 SUPERFAMILY SSF54427 3 141 1.12E-19 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS16765 f5a652fe4687d7685980a019e091104a 172 Gene3D G3DSA:3.10.450.50 2 167 3.9E-21 T 28-03-2018 CNX65_RS09480 43c7f98d957a9a4e15fe4ae8b0533780 149 Pfam PF14430 Immunity protein Imm1 20 142 1.5E-31 T 28-03-2018 IPR025680 Immunity protein Imm1 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 Gene3D G3DSA:1.10.287.130 223 285 2.8E-7 T 28-03-2018 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 408 426 4.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 PRINTS PR00344 Bacterial sensor protein C-terminal signature 377 391 4.2E-8 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 SMART SM00388 233 297 2.0E-7 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 SMART SM00304 179 232 8.5E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 SUPERFAMILY SSF55874 332 444 3.27E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 Pfam PF00672 HAMP domain 179 226 2.3E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 Gene3D G3DSA:3.30.565.10 286 446 1.2E-25 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 SUPERFAMILY SSF158472 179 227 3.14E-5 T 28-03-2018 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 SMART SM00387 341 446 6.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 346 445 7.9E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 SUPERFAMILY SSF47384 216 296 5.89E-10 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS10970 f20e0f735af60574f6479a2715535c9c 448 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 296 5.9E-8 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 224 240 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 Gene3D G3DSA:3.40.50.720 111 286 1.7E-59 T 28-03-2018 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 SUPERFAMILY SSF51735 103 285 1.07E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 SUPERFAMILY SSF55021 456 527 4.2E-12 T 28-03-2018 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 9 529 6.1E-183 T 28-03-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 147 174 - T 28-03-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 Gene3D G3DSA:3.30.70.260 454 528 1.5E-14 T 28-03-2018 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 195 217 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 Pfam PF01842 ACT domain 460 516 9.6E-9 T 28-03-2018 IPR002912 ACT domain CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 Gene3D G3DSA:3.40.50.720 2 110 6.6E-32 T 28-03-2018 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 9 316 1.7E-32 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 SUPERFAMILY SSF143548 325 453 7.32E-30 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 Gene3D G3DSA:3.30.1330.90 319 453 1.1E-28 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 SUPERFAMILY SSF52283 6 137 3.78E-36 T 28-03-2018 CNX65_RS29595 2ea1ee23ac9bf7f4eea972565ce5423a 532 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 110 284 3.2E-61 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CNX65_RS18325 711270eb1306911a292908af8281433d 66 Gene3D G3DSA:3.90.820.10 2 66 1.8E-31 T 28-03-2018 CNX65_RS18325 711270eb1306911a292908af8281433d 66 SUPERFAMILY SSF160582 3 65 3.4E-26 T 28-03-2018 CNX65_RS18325 711270eb1306911a292908af8281433d 66 Pfam PF03621 MbtH-like protein 4 50 5.5E-21 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS18325 711270eb1306911a292908af8281433d 66 SMART SM00923 1 51 1.4E-20 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS30805 8b4657b6d280a4284255763efe2e664d 345 Gene3D G3DSA:1.10.260.40 2 71 1.5E-14 T 28-03-2018 CNX65_RS30805 8b4657b6d280a4284255763efe2e664d 345 SMART SM00530 8 63 2.5E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS30805 8b4657b6d280a4284255763efe2e664d 345 SUPERFAMILY SSF47413 4 66 1.39E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS30805 8b4657b6d280a4284255763efe2e664d 345 Pfam PF13560 Helix-turn-helix domain 8 59 1.4E-12 T 28-03-2018 CNX65_RS30805 8b4657b6d280a4284255763efe2e664d 345 Pfam PF06114 IrrE N-terminal-like domain 166 268 2.6E-12 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 Pfam PF06628 Catalase-related immune-responsive 503 564 6.5E-21 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 SUPERFAMILY SSF52317 601 749 4.98E-8 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 ProSitePatterns PS00437 Catalase proximal heme-ligand signature. 414 422 - T 28-03-2018 IPR002226 Catalase haem-binding site GO:0020037 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 ProSitePatterns PS00438 Catalase proximal active site signature. 120 136 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 PIRSF PIRSF038927 55 753 6.9E-284 T 28-03-2018 IPR024712 Catalase, mono-functional, haem-containing, clade 2 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 PRINTS PR00067 Catalase signature 401 427 3.6E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 PRINTS PR00067 Catalase signature 180 197 3.6E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 PRINTS PR00067 Catalase signature 199 217 3.6E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 PRINTS PR00067 Catalase signature 97 120 3.6E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 PRINTS PR00067 Catalase signature 369 396 3.6E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 PRINTS PR00067 Catalase signature 159 177 3.6E-68 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 Gene3D G3DSA:3.40.50.880 593 752 2.5E-18 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 Gene3D G3DSA:2.40.180.10 60 439 2.4E-154 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 SUPERFAMILY SSF56634 74 577 4.06E-201 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 Pfam PF00199 Catalase 84 469 1.9E-164 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS12770 aec1c9140f9fff3674e88bd4b914c972 755 SMART SM01060 84 472 2.7E-247 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS24290 6561b168cb1725ec44fc13d0d4baf3e9 571 SUPERFAMILY SSF161098 378 555 1.54E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS24290 6561b168cb1725ec44fc13d0d4baf3e9 571 Gene3D G3DSA:1.10.3720.10 8 300 3.5E-19 T 28-03-2018 CNX65_RS24290 6561b168cb1725ec44fc13d0d4baf3e9 571 Gene3D G3DSA:1.10.3720.10 301 564 7.9E-20 T 28-03-2018 CNX65_RS24290 6561b168cb1725ec44fc13d0d4baf3e9 571 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 404 561 1.1E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS24290 6561b168cb1725ec44fc13d0d4baf3e9 571 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 142 301 2.3E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS24290 6561b168cb1725ec44fc13d0d4baf3e9 571 SUPERFAMILY SSF161098 94 290 6.54E-5 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 Gene3D G3DSA:3.30.300.30 523 620 2.3E-26 T 28-03-2018 CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 612 4.6E-20 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 Gene3D G3DSA:3.40.50.980 300 443 1.1E-27 T 28-03-2018 CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 Pfam PF00501 AMP-binding enzyme 49 529 6.2E-61 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 Gene3D G3DSA:2.30.38.10 444 522 1.9E-14 T 28-03-2018 CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 SUPERFAMILY SSF56801 45 167 6.41E-106 T 28-03-2018 CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 SUPERFAMILY SSF56801 272 618 6.41E-106 T 28-03-2018 CNX65_RS05355 ab30bb6614acf1d660385dd2b2e48026 620 Gene3D G3DSA:3.40.50.980 38 299 1.7E-28 T 28-03-2018 CNX65_RS24265 3a04fe756d036e413cfa9d4b64cf9348 345 SUPERFAMILY SSF52799 113 344 2.31E-46 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CNX65_RS24265 3a04fe756d036e413cfa9d4b64cf9348 345 ProSitePatterns PS00383 Tyrosine specific protein phosphatases active site. 258 268 - T 28-03-2018 IPR016130 Protein-tyrosine phosphatase, active site GO:0004725|GO:0016311 CNX65_RS24265 3a04fe756d036e413cfa9d4b64cf9348 345 Gene3D G3DSA:3.90.190.10 126 309 1.2E-23 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CNX65_RS24265 3a04fe756d036e413cfa9d4b64cf9348 345 Pfam PF13350 Tyrosine phosphatase family 114 344 1.4E-52 T 28-03-2018 IPR026893 Tyrosine/serine-protein phosphatase IphP-type CNX65_RS16930 dd17c47e57134e88cb2cf156269b3a9a 457 Gene3D G3DSA:1.20.1250.20 253 453 1.4E-16 T 28-03-2018 CNX65_RS16930 dd17c47e57134e88cb2cf156269b3a9a 457 SUPERFAMILY SSF103473 15 200 2.35E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS16930 dd17c47e57134e88cb2cf156269b3a9a 457 SUPERFAMILY SSF103473 249 443 2.35E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS16930 dd17c47e57134e88cb2cf156269b3a9a 457 Pfam PF07690 Major Facilitator Superfamily 23 410 1.1E-43 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS16930 dd17c47e57134e88cb2cf156269b3a9a 457 Gene3D G3DSA:1.20.1250.20 10 199 1.4E-24 T 28-03-2018 CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 SMART SM00487 71 271 8.7E-55 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 Gene3D G3DSA:3.40.50.300 272 589 3.1E-43 T 28-03-2018 CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 Gene3D G3DSA:3.40.50.300 24 271 1.2E-56 T 28-03-2018 CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 Pfam PF00271 Helicase conserved C-terminal domain 279 388 1.0E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 SMART SM00490 307 388 1.5E-32 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 Pfam PF00270 DEAD/DEAH box helicase 77 237 8.6E-52 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 200 208 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CNX65_RS04065 1bea6f221288b0ce4f250e448e843772 593 SUPERFAMILY SSF52540 122 408 2.37E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21460 e1591322e562a0ba5b48c4d4254aa6f5 118 Gene3D G3DSA:1.10.10.10 2 113 7.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21460 e1591322e562a0ba5b48c4d4254aa6f5 118 SUPERFAMILY SSF46785 14 104 2.91E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21460 e1591322e562a0ba5b48c4d4254aa6f5 118 Pfam PF01022 Bacterial regulatory protein, arsR family 34 79 1.1E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21460 e1591322e562a0ba5b48c4d4254aa6f5 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 44 8.0E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21460 e1591322e562a0ba5b48c4d4254aa6f5 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 76 91 8.0E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21460 e1591322e562a0ba5b48c4d4254aa6f5 118 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 61 76 8.0E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21460 e1591322e562a0ba5b48c4d4254aa6f5 118 SMART SM00418 27 105 1.6E-23 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 Gene3D G3DSA:1.10.390.10 321 477 6.1E-30 T 28-03-2018 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 354 366 6.6E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 335 350 6.6E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 191 206 6.6E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 238 253 6.6E-9 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 Gene3D G3DSA:2.60.40.1730 69 255 9.9E-36 T 28-03-2018 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 SUPERFAMILY SSF63737 60 253 1.57E-30 T 28-03-2018 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 Pfam PF01433 Peptidase family M1 domain 334 473 2.1E-20 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS01745 94fb718aa02d9b446fed7908524d2695 492 SUPERFAMILY SSF55486 279 480 9.52E-39 T 28-03-2018 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 13 184 4.4E-42 T 28-03-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 SUPERFAMILY SSF53335 206 377 3.31E-28 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 PIRSF PIRSF036428 7 391 1.1E-129 T 28-03-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|KEGG: 00860+2.1.1.132|MetaCyc: PWY-2201|MetaCyc: PWY-3841 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 Gene3D G3DSA:3.40.50.150 213 390 7.3E-29 T 28-03-2018 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 Gene3D G3DSA:3.40.1010.10 9 120 4.1E-19 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 Gene3D G3DSA:3.30.950.10 121 199 1.3E-17 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 219 341 5.7E-32 T 28-03-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00670+2.1.1.19|KEGG: 00860+2.1.1.196|MetaCyc: PWY-2201|MetaCyc: PWY-7377 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 11 183 4.2E-19 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08860 225f0ccea2a9a44240e2d923834cae8e 392 SUPERFAMILY SSF53790 11 186 2.09E-39 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS24945 d9e5ea77170fc8c151c417dd28420a33 549 SUPERFAMILY SSF52540 336 542 3.66E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24945 d9e5ea77170fc8c151c417dd28420a33 549 Gene3D G3DSA:3.40.50.300 332 547 1.8E-43 T 28-03-2018 CNX65_RS24945 d9e5ea77170fc8c151c417dd28420a33 549 Gene3D G3DSA:1.20.1560.10 2 318 6.6E-45 T 28-03-2018 CNX65_RS24945 d9e5ea77170fc8c151c417dd28420a33 549 SUPERFAMILY SSF90123 7 314 3.66E-52 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS24945 d9e5ea77170fc8c151c417dd28420a33 549 Pfam PF00005 ABC transporter 337 480 5.8E-18 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS24945 d9e5ea77170fc8c151c417dd28420a33 549 Pfam PF00664 ABC transporter transmembrane region 21 283 6.0E-24 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS24945 d9e5ea77170fc8c151c417dd28420a33 549 ProSitePatterns PS00211 ABC transporters family signature. 453 467 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 Gene3D G3DSA:3.40.50.2300 73 193 4.9E-34 T 28-03-2018 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 Pfam PF13377 Periplasmic binding protein-like domain 186 342 2.7E-29 T 28-03-2018 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 SUPERFAMILY SSF53822 77 337 5.89E-59 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 Pfam PF00356 Bacterial regulatory proteins, lacI family 20 65 4.5E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 ProSitePatterns PS00356 LacI-type HTH domain signature. 21 39 - T 28-03-2018 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 20 30 1.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 30 40 1.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 Gene3D G3DSA:3.40.50.2300 194 326 8.6E-31 T 28-03-2018 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 Gene3D G3DSA:1.10.10.10 9 32 9.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 Gene3D G3DSA:1.10.260.40 33 72 1.1E-22 T 28-03-2018 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 SUPERFAMILY SSF47413 17 76 1.36E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS29960 9c76e607df0b87b7a7f80b31922c5c70 347 SMART SM00354 18 89 1.0E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS13430 7898c8eeb4cdb18c3cf9e069327dd8be 160 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 7 151 1.2E-33 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS13430 7898c8eeb4cdb18c3cf9e069327dd8be 160 PIRSF PIRSF005384 5 154 3.8E-45 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS13430 7898c8eeb4cdb18c3cf9e069327dd8be 160 Gene3D G3DSA:3.40.1400.10 3 156 1.0E-53 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS13430 7898c8eeb4cdb18c3cf9e069327dd8be 160 TIGRFAM TIGR02133 RPI_actino: ribose 5-phosphate isomerase 5 151 5.5E-63 T 28-03-2018 IPR011860 Ribose 5-phosphate isomerase GO:0004751 CNX65_RS13430 7898c8eeb4cdb18c3cf9e069327dd8be 160 Pfam PF02502 Ribose/Galactose Isomerase 7 145 1.3E-43 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS13430 7898c8eeb4cdb18c3cf9e069327dd8be 160 SUPERFAMILY SSF89623 4 151 1.7E-46 T 28-03-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 CNX65_RS06010 9b415a8df3c56cb5489892b0d9c229c6 323 SUPERFAMILY SSF48019 198 314 1.67E-11 T 28-03-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 CNX65_RS06010 9b415a8df3c56cb5489892b0d9c229c6 323 SUPERFAMILY SSF52540 4 178 1.05E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06010 9b415a8df3c56cb5489892b0d9c229c6 323 Gene3D G3DSA:1.10.8.60 130 205 6.9E-11 T 28-03-2018 CNX65_RS06010 9b415a8df3c56cb5489892b0d9c229c6 323 Gene3D G3DSA:3.40.50.300 3 125 1.5E-10 T 28-03-2018 CNX65_RS06010 9b415a8df3c56cb5489892b0d9c229c6 323 Gene3D G3DSA:1.20.272.10 206 323 4.4E-21 T 28-03-2018 CNX65_RS34990 dde956d3ec673276820d7093c47e1ab3 203 SUPERFAMILY SSF88946 6 107 1.24E-29 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34990 dde956d3ec673276820d7093c47e1ab3 203 Gene3D G3DSA:1.10.1740.10 2 94 4.3E-27 T 28-03-2018 CNX65_RS34990 dde956d3ec673276820d7093c47e1ab3 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 176 4.9E-30 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34990 dde956d3ec673276820d7093c47e1ab3 203 Pfam PF08281 Sigma-70, region 4 122 173 1.0E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34990 dde956d3ec673276820d7093c47e1ab3 203 Pfam PF04542 Sigma-70 region 2 26 92 9.0E-17 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34990 dde956d3ec673276820d7093c47e1ab3 203 Gene3D G3DSA:1.10.10.10 95 180 8.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34990 dde956d3ec673276820d7093c47e1ab3 203 SUPERFAMILY SSF88659 113 178 9.59E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS04230 ae4597c6c58c5e04a2ea1189745927b7 302 Pfam PF04228 Putative neutral zinc metallopeptidase 102 294 5.3E-16 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CNX65_RS33720 434fbb7d995b3d1be5cccca823a46fa2 304 Gene3D G3DSA:1.10.3720.10 22 293 2.5E-39 T 28-03-2018 CNX65_RS33720 434fbb7d995b3d1be5cccca823a46fa2 304 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 30 296 2.6E-80 T 28-03-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 CNX65_RS33720 434fbb7d995b3d1be5cccca823a46fa2 304 SUPERFAMILY SSF161098 36 292 2.06E-39 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS33720 434fbb7d995b3d1be5cccca823a46fa2 304 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 303 2.5E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 95 108 - T 28-03-2018 IPR020583 Inositol monophosphatase, metal-binding site CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 Pfam PF00459 Inositol monophosphatase family 22 256 3.6E-46 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 Gene3D G3DSA:3.30.540.10 15 174 9.1E-46 T 28-03-2018 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 76 92 8.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 54 74 8.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 95 111 8.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 230 254 8.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 PRINTS PR00377 Inositol monophosphatase superfamily signature 155 178 8.5E-23 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 TIGRFAM TIGR02067 his_9_HisN: histidinol-phosphatase 22 278 3.4E-88 T 28-03-2018 IPR011809 Histidinol-phosphate phosphatase, putative, inositol monophosphatase GO:0004401 KEGG: 00340+3.1.3.15 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 Gene3D G3DSA:3.40.190.80 175 283 7.6E-20 T 28-03-2018 CNX65_RS31330 59907bce76425431176aa2b2d38ac5aa 283 SUPERFAMILY SSF56655 17 280 3.27E-69 T 28-03-2018 CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 Hamap MF_02040 Iron-sulfur cluster carrier protein. 108 363 33.826 T 28-03-2018 IPR019591 Mrp/NBP35 ATP-binding protein CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 117 362 1.7E-88 T 28-03-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 ProSitePatterns PS01215 Mrp family signature. 221 237 - T 28-03-2018 IPR000808 Mrp, conserved site GO:0005524 CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 SUPERFAMILY SSF117916 10 100 5.56E-23 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 Pfam PF01883 Iron-sulfur cluster assembly protein 11 83 2.6E-19 T 28-03-2018 IPR002744 MIP18 family-like CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 Gene3D G3DSA:3.40.50.300 95 371 1.7E-55 T 28-03-2018 CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 SUPERFAMILY SSF52540 116 365 2.31E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03950 ffa060320d0d8ac198269000e1248f3d 381 Gene3D G3DSA:3.30.300.130 8 94 1.1E-20 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CNX65_RS14060 c7500933b3a5ce7b6ff71a8ca286a547 185 SUPERFAMILY SSF48498 85 180 2.67E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS14060 c7500933b3a5ce7b6ff71a8ca286a547 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 2.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14060 c7500933b3a5ce7b6ff71a8ca286a547 185 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 2.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14060 c7500933b3a5ce7b6ff71a8ca286a547 185 Gene3D G3DSA:1.10.357.10 2 183 2.9E-37 T 28-03-2018 CNX65_RS14060 c7500933b3a5ce7b6ff71a8ca286a547 185 SUPERFAMILY SSF46689 3 82 1.3E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14060 c7500933b3a5ce7b6ff71a8ca286a547 185 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 2.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 Gene3D G3DSA:3.50.50.60 154 270 1.0E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 SUPERFAMILY SSF51905 138 322 3.14E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 Gene3D G3DSA:3.50.50.60 271 351 0.15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 165 189 4.5E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 4.5E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 126 134 4.5E-13 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PIRSF PIRSF000332 5 208 1.1E-17 T 28-03-2018 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PIRSF PIRSF000332 255 300 0.58 T 28-03-2018 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 SUPERFAMILY SSF51905 4 191 7.9E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 169 187 1.9E-11 T 28-03-2018 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.9E-11 T 28-03-2018 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 277 293 1.9E-11 T 28-03-2018 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 199 4.7E-30 T 28-03-2018 CNX65_RS19445 33dcf3f589c47d98ce1082dded304ab5 353 Gene3D G3DSA:3.50.50.60 4 153 1.1E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22840 9ef42b29b0419f74b103f8584772dc3e 373 Gene3D G3DSA:3.40.630.30 3 145 0.0016 T 28-03-2018 CNX65_RS22840 9ef42b29b0419f74b103f8584772dc3e 373 SUPERFAMILY SSF55729 168 324 7.71E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS22840 9ef42b29b0419f74b103f8584772dc3e 373 Pfam PF13480 Acetyltransferase (GNAT) domain 176 310 1.2E-6 T 28-03-2018 CNX65_RS22840 9ef42b29b0419f74b103f8584772dc3e 373 Gene3D G3DSA:3.40.630.30 155 337 8.1E-13 T 28-03-2018 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 SUPERFAMILY SSF56719 9 496 3.4E-167 T 28-03-2018 IPR013760 DNA topoisomerase, type IIA-like domain GO:0003918|GO:0005524 Reactome: R-HSA-4615885 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 665 713 3.0E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 511 558 2.4E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 768 812 8.6E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 561 608 8.6E-12 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 719 765 1.9E-11 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 618 661 6.0E-10 T 28-03-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 SMART SM00434 14 472 1.1E-255 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Gene3D G3DSA:2.120.10.90 503 816 1.5E-120 T 28-03-2018 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Gene3D G3DSA:3.90.199.10 37 219 2.2E-81 T 28-03-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 12 816 23.433 T 28-03-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 13 814 0.0 T 28-03-2018 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 35 479 6.5E-148 T 28-03-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Gene3D G3DSA:3.30.1360.40 243 340 1.1E-32 T 28-03-2018 IPR024946 Arginine repressor C-terminal-like domain Reactome: R-HSA-4615885 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 Gene3D G3DSA:1.10.268.10 352 494 5.6E-45 T 28-03-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 CNX65_RS00035 f9d6f5bf3e67d2a16ba7785a488a8498 834 SUPERFAMILY SSF101904 506 820 4.32E-101 T 28-03-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Gene3D G3DSA:1.10.287.130 484 554 2.0E-15 T 28-03-2018 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Pfam PF08448 PAS fold 240 347 6.7E-7 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SUPERFAMILY SSF55785 235 347 1.06E-8 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SUPERFAMILY SSF55874 547 716 5.79E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SUPERFAMILY SSF55785 116 208 1.58E-8 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SMART SM00091 97 169 1.2 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SMART SM00091 359 429 2.0 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SMART SM00091 232 299 2.8 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SMART SM00388 491 558 2.1E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Gene3D G3DSA:3.30.450.20 231 356 2.8E-15 T 28-03-2018 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Gene3D G3DSA:3.30.450.20 357 483 2.7E-17 T 28-03-2018 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SUPERFAMILY SSF47384 477 558 1.45E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Gene3D G3DSA:3.30.450.20 90 214 2.2E-8 T 28-03-2018 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 232 353 9.1E-6 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 114 199 6.5E-7 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Pfam PF00989 PAS fold 117 193 1.6E-7 T 28-03-2018 IPR013767 PAS fold GO:0006355 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 SUPERFAMILY SSF55785 344 469 1.05E-12 T 28-03-2018 IPR000014 PAS domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Pfam PF00512 His Kinase A (phospho-acceptor) domain 492 558 2.3E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Gene3D G3DSA:3.30.565.10 562 718 3.7E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12045 965ec9a1ba57c1e0d5f09e4716f28af5 722 Pfam PF13188 PAS domain 360 401 0.013 T 28-03-2018 IPR000014 PAS domain CNX65_RS02960 e81837e3ad5ece8aae18d2389cf3f170 68 Pfam PF12728 Helix-turn-helix domain 11 61 2.0E-7 T 28-03-2018 CNX65_RS02960 e81837e3ad5ece8aae18d2389cf3f170 68 Gene3D G3DSA:1.10.10.10 4 68 3.7E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33975 18bf7fb671a41f949cea3b0a2b218015 282 Gene3D G3DSA:3.20.20.80 59 282 4.8E-59 T 28-03-2018 CNX65_RS33975 18bf7fb671a41f949cea3b0a2b218015 282 Pfam PF01183 Glycosyl hydrolases family 25 80 264 7.0E-47 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CNX65_RS33975 18bf7fb671a41f949cea3b0a2b218015 282 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 81 114 - T 28-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 CNX65_RS33975 18bf7fb671a41f949cea3b0a2b218015 282 SMART SM00641 77 186 1.1E-37 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CNX65_RS33975 18bf7fb671a41f949cea3b0a2b218015 282 SUPERFAMILY SSF51445 77 280 4.49E-59 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS26990 3ae2f43f5d6e340a266916a77a2bd7c8 294 Gene3D G3DSA:3.40.50.300 1 285 4.5E-61 T 28-03-2018 CNX65_RS26990 3ae2f43f5d6e340a266916a77a2bd7c8 294 SMART SM00382 33 214 4.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS26990 3ae2f43f5d6e340a266916a77a2bd7c8 294 SUPERFAMILY SSF52540 4 235 5.32E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26990 3ae2f43f5d6e340a266916a77a2bd7c8 294 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS26990 3ae2f43f5d6e340a266916a77a2bd7c8 294 Pfam PF00005 ABC transporter 25 165 4.4E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS21065 989557ee89efd2a34d20b5521658f031 331 SUPERFAMILY SSF103481 57 148 2.75E-6 T 28-03-2018 CNX65_RS21065 989557ee89efd2a34d20b5521658f031 331 Pfam PF00892 EamA-like transporter family 12 146 1.1E-11 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS31265 c475c9d074d99ebc42ab158b21ff810e 166 Gene3D G3DSA:3.40.50.7700 1 153 1.4E-68 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CNX65_RS31265 c475c9d074d99ebc42ab158b21ff810e 166 PIRSF PIRSF001338 1 155 1.7E-65 T 28-03-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 CNX65_RS31265 c475c9d074d99ebc42ab158b21ff810e 166 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 1 151 6.4E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CNX65_RS31265 c475c9d074d99ebc42ab158b21ff810e 166 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 1 148 30.245 T 28-03-2018 IPR033747 Class I PurE CNX65_RS31265 c475c9d074d99ebc42ab158b21ff810e 166 Pfam PF00731 AIR carboxylase 1 141 8.7E-64 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CNX65_RS31265 c475c9d074d99ebc42ab158b21ff810e 166 SUPERFAMILY SSF52255 1 154 2.09E-63 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CNX65_RS31265 c475c9d074d99ebc42ab158b21ff810e 166 SMART SM01001 1 144 1.3E-88 T 28-03-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 CNX65_RS30840 9b1336a6f188b4518461ffc262b2bfed 391 TIGRFAM TIGR01879 hydantase: amidase, hydantoinase/carbamoylase family 3 386 3.7E-80 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CNX65_RS30840 9b1336a6f188b4518461ffc262b2bfed 391 Pfam PF01546 Peptidase family M20/M25/M40 68 387 3.8E-24 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS30840 9b1336a6f188b4518461ffc262b2bfed 391 PIRSF PIRSF001235 1 391 6.1E-108 T 28-03-2018 IPR010158 Amidase, carbamoylase-type GO:0008152|GO:0016813 CNX65_RS30840 9b1336a6f188b4518461ffc262b2bfed 391 SUPERFAMILY SSF55031 203 309 8.72E-19 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS30840 9b1336a6f188b4518461ffc262b2bfed 391 SUPERFAMILY SSF53187 4 210 8.38E-61 T 28-03-2018 CNX65_RS30840 9b1336a6f188b4518461ffc262b2bfed 391 SUPERFAMILY SSF53187 320 390 8.38E-61 T 28-03-2018 CNX65_RS30840 9b1336a6f188b4518461ffc262b2bfed 391 Gene3D G3DSA:3.40.630.10 1 391 8.6E-45 T 28-03-2018 CNX65_RS01010 0f95f9217437c7836f9e377e252f1e9c 407 Pfam PF04188 Mannosyltransferase (PIG-V) 61 194 5.3E-5 T 28-03-2018 IPR007315 GPI mannosyltransferase 2 GO:0004584|GO:0006506 Reactome: R-HSA-162710 CNX65_RS08295 2028bff9c5a2c25abe80bceedaa3c976 185 SUPERFAMILY SSF53098 6 144 5.56E-54 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS08295 2028bff9c5a2c25abe80bceedaa3c976 185 Hamap MF_00042 Ribonuclease H [rnhA]. 3 153 31.402 T 28-03-2018 IPR022892 Ribonuclease HI GO:0004523 CNX65_RS08295 2028bff9c5a2c25abe80bceedaa3c976 185 Pfam PF00075 RNase H 6 143 7.9E-47 T 28-03-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 CNX65_RS08295 2028bff9c5a2c25abe80bceedaa3c976 185 Gene3D G3DSA:3.30.420.10 1 147 2.7E-50 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS02130 5da7a033a8c08432f6b07ae6483540e0 234 Gene3D G3DSA:3.40.50.1820 2 233 1.8E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02130 5da7a033a8c08432f6b07ae6483540e0 234 SUPERFAMILY SSF53474 3 228 2.84E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02130 5da7a033a8c08432f6b07ae6483540e0 234 Pfam PF12697 Alpha/beta hydrolase family 6 224 3.2E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04110 eed67a1411fea6cda20c76acfd33a3b2 390 SMART SM00450 287 385 2.4E-29 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS04110 eed67a1411fea6cda20c76acfd33a3b2 390 Gene3D G3DSA:3.40.50.720 10 260 4.2E-71 T 28-03-2018 CNX65_RS04110 eed67a1411fea6cda20c76acfd33a3b2 390 SUPERFAMILY SSF69572 7 357 6.15E-99 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CNX65_RS04110 eed67a1411fea6cda20c76acfd33a3b2 390 Gene3D G3DSA:3.40.250.10 266 386 1.3E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS04110 eed67a1411fea6cda20c76acfd33a3b2 390 Pfam PF00899 ThiF family 21 258 5.2E-64 T 28-03-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 CNX65_RS04110 eed67a1411fea6cda20c76acfd33a3b2 390 Pfam PF00581 Rhodanese-like domain 289 381 2.5E-14 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS34900 cff7995220c2ec62a097685f05e79824 394 SUPERFAMILY SSF53383 7 391 1.33E-116 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS34900 cff7995220c2ec62a097685f05e79824 394 TIGRFAM TIGR01822 2am3keto_CoA: glycine C-acetyltransferase 5 388 1.1E-192 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 CNX65_RS34900 cff7995220c2ec62a097685f05e79824 394 Pfam PF00155 Aminotransferase class I and II 44 385 9.5E-66 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS34900 cff7995220c2ec62a097685f05e79824 394 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 239 248 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CNX65_RS34900 cff7995220c2ec62a097685f05e79824 394 Hamap MF_00985 2-amino-3-ketobutyrate coenzyme A ligase [kbl]. 2 393 53.854 T 28-03-2018 IPR011282 2-amino-3-ketobutyrate coenzyme A ligase GO:0006567|GO:0008890 KEGG: 00260+2.3.1.29|Reactome: R-HSA-8849175 CNX65_RS34900 cff7995220c2ec62a097685f05e79824 394 Gene3D G3DSA:3.40.640.10 58 285 8.5E-57 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS34900 cff7995220c2ec62a097685f05e79824 394 Gene3D G3DSA:3.90.1150.10 286 394 3.2E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS06670 0505189ce1e8d312f7af4c34472f0e07 297 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 218 1.6E-13 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS06670 0505189ce1e8d312f7af4c34472f0e07 297 Gene3D G3DSA:3.40.50.720 1 296 1.3E-34 T 28-03-2018 CNX65_RS06670 0505189ce1e8d312f7af4c34472f0e07 297 SUPERFAMILY SSF51735 1 282 4.85E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06670 0505189ce1e8d312f7af4c34472f0e07 297 Pfam PF08338 Domain of unknown function (DUF1731) 246 292 7.2E-15 T 28-03-2018 IPR013549 Domain of unknown function DUF1731 CNX65_RS06670 0505189ce1e8d312f7af4c34472f0e07 297 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 290 1.1E-93 T 28-03-2018 IPR010099 Epimerase family protein SDR39U1 CNX65_RS20110 9680f01ee7ca345ec0f2917550694a97 536 SUPERFAMILY SSF51735 270 499 8.28E-40 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20110 9680f01ee7ca345ec0f2917550694a97 536 Pfam PF00106 short chain dehydrogenase 274 401 9.3E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20110 9680f01ee7ca345ec0f2917550694a97 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 274 291 3.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20110 9680f01ee7ca345ec0f2917550694a97 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 446 463 3.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20110 9680f01ee7ca345ec0f2917550694a97 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 343 354 3.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20110 9680f01ee7ca345ec0f2917550694a97 536 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 385 401 3.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20110 9680f01ee7ca345ec0f2917550694a97 536 Gene3D G3DSA:3.40.50.720 260 533 1.5E-41 T 28-03-2018 CNX65_RS10540 6eeea6d0c2d7ac44e16e3725c90a8037 98 ProSitePatterns PS00768 Transthyretin signature 1. 6 21 - T 28-03-2018 IPR023418 Transthyretin, thyroxine binding site Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CNX65_RS10540 6eeea6d0c2d7ac44e16e3725c90a8037 98 TIGRFAM TIGR02962 hdxy_isourate: hydroxyisourate hydrolase 2 98 4.3E-26 T 28-03-2018 IPR014306 Hydroxyisourate hydrolase GO:0006144|GO:0033971 KEGG: 00230+3.5.2.17|MetaCyc: PWY-5691|MetaCyc: PWY-7394|MetaCyc: PWY-7849 CNX65_RS10540 6eeea6d0c2d7ac44e16e3725c90a8037 98 SUPERFAMILY SSF49472 2 98 1.14E-30 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CNX65_RS10540 6eeea6d0c2d7ac44e16e3725c90a8037 98 Gene3D G3DSA:2.60.40.180 1 98 7.2E-30 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CNX65_RS10540 6eeea6d0c2d7ac44e16e3725c90a8037 98 Pfam PF00576 HIUase/Transthyretin family 3 97 3.9E-25 T 28-03-2018 IPR023416 Transthyretin/hydroxyisourate hydrolase, superfamily Reactome: R-HSA-2453864|Reactome: R-HSA-2453902|Reactome: R-HSA-3000171|Reactome: R-HSA-6798695|Reactome: R-HSA-975634|Reactome: R-HSA-977225 CNX65_RS02090 4a11b7bf1d0ce3aa9f53093138355265 237 Pfam PF02581 Thiamine monophosphate synthase 18 213 1.4E-49 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CNX65_RS02090 4a11b7bf1d0ce3aa9f53093138355265 237 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 17 160 1.6E-43 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CNX65_RS02090 4a11b7bf1d0ce3aa9f53093138355265 237 SUPERFAMILY SSF51391 9 227 2.88E-56 T 28-03-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CNX65_RS02090 4a11b7bf1d0ce3aa9f53093138355265 237 Gene3D G3DSA:3.20.20.70 7 230 3.4E-43 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS02090 4a11b7bf1d0ce3aa9f53093138355265 237 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 16 231 24.623 T 28-03-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CNX65_RS05370 504b75c27d511ffdd07f47af2b8d9d0a 201 Pfam PF02525 Flavodoxin-like fold 2 172 9.6E-35 T 28-03-2018 IPR003680 Flavodoxin-like fold CNX65_RS05370 504b75c27d511ffdd07f47af2b8d9d0a 201 Gene3D G3DSA:3.40.50.360 1 201 2.0E-40 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS05370 504b75c27d511ffdd07f47af2b8d9d0a 201 SUPERFAMILY SSF52218 2 186 4.04E-36 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS05370 504b75c27d511ffdd07f47af2b8d9d0a 201 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 1 199 23.956 T 28-03-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 CNX65_RS16690 0c7594f844bfc08ed4b479401cd0d153 85 Pfam PF05402 Coenzyme PQQ synthesis protein D (PqqD) 18 82 6.7E-11 T 28-03-2018 IPR008792 Coenzyme PQQ synthesis D CNX65_RS30545 ec57bdb23c49ce7a3246090a50e8beb6 375 SUPERFAMILY SSF56601 42 340 1.23E-74 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS30545 ec57bdb23c49ce7a3246090a50e8beb6 375 Pfam PF00144 Beta-lactamase 51 341 1.5E-59 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS30545 ec57bdb23c49ce7a3246090a50e8beb6 375 Gene3D G3DSA:3.40.710.10 37 373 5.3E-76 T 28-03-2018 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 SUPERFAMILY SSF53474 2 293 4.93E-61 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 121 134 8.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 57 72 8.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 8.3E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 TIGRFAM TIGR01249 pro_imino_pep_1: prolyl aminopeptidase 6 309 6.6E-113 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 Gene3D G3DSA:3.40.50.1820 1 309 1.9E-62 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 PIRSF PIRSF006431 1 311 2.1E-130 T 28-03-2018 IPR005944 Proline iminopeptidase GO:0004177|GO:0005737|GO:0006508 KEGG: 00330+3.4.11.5 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 Pfam PF00561 alpha/beta hydrolase fold 32 292 6.5E-30 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 34 42 3.6E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 60 71 3.6E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS04415 ee1d07bd508dfd54b09440dd6ca39044 311 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 107 121 3.6E-14 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 SUPERFAMILY SSF52743 91 423 1.44E-67 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 362 372 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 PRINTS PR00723 Subtilisin serine protease family (S8) signature 361 377 1.4E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 PRINTS PR00723 Subtilisin serine protease family (S8) signature 108 127 1.4E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 PRINTS PR00723 Subtilisin serine protease family (S8) signature 148 161 1.4E-16 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 Pfam PF00082 Subtilase family 108 413 4.6E-40 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 Gene3D G3DSA:3.40.50.200 58 427 1.8E-74 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 TIGRFAM TIGR03921 T7SS_mycosin: type VII secretion-associated serine protease mycosin 97 485 5.6E-106 T 28-03-2018 IPR023834 Type VII secretion system peptidase S8A, mycosin CNX65_RS32255 2772fe7c172bff7b39c6359052cdf7d0 492 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 152 162 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS35055 3386ec207e66868f9c7e3dfce194fc73 155 SUPERFAMILY SSF55811 5 141 4.06E-30 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS35055 3386ec207e66868f9c7e3dfce194fc73 155 Pfam PF00293 NUDIX domain 9 130 1.0E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS35055 3386ec207e66868f9c7e3dfce194fc73 155 PRINTS PR00502 NUDIX hydrolase family signature 50 65 4.3E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS35055 3386ec207e66868f9c7e3dfce194fc73 155 PRINTS PR00502 NUDIX hydrolase family signature 36 50 4.3E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS35055 3386ec207e66868f9c7e3dfce194fc73 155 Gene3D G3DSA:3.90.79.10 1 145 5.3E-28 T 28-03-2018 CNX65_RS35055 3386ec207e66868f9c7e3dfce194fc73 155 ProSitePatterns PS00893 Nudix box signature. 41 62 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS01525 64a86a64163177db47952c0be8691780 297 Gene3D G3DSA:3.90.550.10 4 285 1.8E-10 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS01525 64a86a64163177db47952c0be8691780 297 SUPERFAMILY SSF53448 26 188 1.69E-17 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS03125 62f9b4744affde6d0d782f736415dce6 219 SUPERFAMILY SSF55729 28 197 1.0E-36 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS03125 62f9b4744affde6d0d782f736415dce6 219 Gene3D G3DSA:3.40.630.30 15 216 7.7E-25 T 28-03-2018 CNX65_RS03125 62f9b4744affde6d0d782f736415dce6 219 Pfam PF13302 Acetyltransferase (GNAT) domain 29 173 7.8E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS21365 dd87cb38ba4c90264e6c58d5ce48c87a 117 Pfam PF03551 Transcriptional regulator PadR-like family 23 92 1.5E-18 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS21365 dd87cb38ba4c90264e6c58d5ce48c87a 117 Gene3D G3DSA:1.10.10.10 2 115 1.2E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21365 dd87cb38ba4c90264e6c58d5ce48c87a 117 SUPERFAMILY SSF46785 20 108 1.19E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08945 8e80a417d03c0d657e00cdc786c0fe9a 382 Gene3D G3DSA:1.10.10.10 6 64 7.1E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08945 8e80a417d03c0d657e00cdc786c0fe9a 382 SUPERFAMILY SSF46785 1 63 1.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08945 8e80a417d03c0d657e00cdc786c0fe9a 382 Pfam PF00480 ROK family 76 363 5.1E-46 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS08945 8e80a417d03c0d657e00cdc786c0fe9a 382 SUPERFAMILY SSF53067 75 368 3.66E-48 T 28-03-2018 CNX65_RS08945 8e80a417d03c0d657e00cdc786c0fe9a 382 Gene3D G3DSA:3.30.420.40 65 193 1.0E-24 T 28-03-2018 CNX65_RS08945 8e80a417d03c0d657e00cdc786c0fe9a 382 Gene3D G3DSA:3.30.420.40 194 374 2.8E-48 T 28-03-2018 CNX65_RS14150 96b4d2a7cc79f3fe042f60bac0c65296 239 SUPERFAMILY SSF55781 24 160 5.49E-11 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14150 96b4d2a7cc79f3fe042f60bac0c65296 239 Gene3D G3DSA:1.10.10.10 180 228 6.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14150 96b4d2a7cc79f3fe042f60bac0c65296 239 PIRSF PIRSF036625 4 236 3.1E-31 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CNX65_RS14150 96b4d2a7cc79f3fe042f60bac0c65296 239 Pfam PF13185 GAF domain 20 158 1.1E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS14150 96b4d2a7cc79f3fe042f60bac0c65296 239 SMART SM01012 166 226 0.0062 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS14150 96b4d2a7cc79f3fe042f60bac0c65296 239 Gene3D G3DSA:3.30.450.40 2 174 7.1E-15 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 172 183 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 29 252 2.0E-75 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 SUPERFAMILY SSF46548 131 256 8.02E-33 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 SUPERFAMILY SSF54292 23 130 6.13E-27 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 26 136 2.4E-33 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 Gene3D G3DSA:1.10.1060.10 131 259 2.5E-27 T 28-03-2018 CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 Gene3D G3DSA:3.10.20.30 17 130 9.7E-31 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS31720 c3179a8d56ded4522e872e86da369739 260 Pfam PF13183 4Fe-4S dicluster domain 170 242 1.9E-10 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS19080 fdae3ef6d2f33cacf43839b587cc68dc 108 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 7 94 4.3E-16 T 28-03-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 CNX65_RS18000 6b630e40aad7903ae9c7c7af22d8e4ff 623 Pfam PF13632 Glycosyl transferase family group 2 171 254 3.4E-7 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS18000 6b630e40aad7903ae9c7c7af22d8e4ff 623 SUPERFAMILY SSF51735 378 510 3.35E-12 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18000 6b630e40aad7903ae9c7c7af22d8e4ff 623 Gene3D G3DSA:3.40.50.720 303 540 6.0E-11 T 28-03-2018 CNX65_RS18000 6b630e40aad7903ae9c7c7af22d8e4ff 623 SUPERFAMILY SSF53448 10 231 6.75E-46 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS18000 6b630e40aad7903ae9c7c7af22d8e4ff 623 Pfam PF00535 Glycosyl transferase family 2 11 124 1.4E-18 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS18000 6b630e40aad7903ae9c7c7af22d8e4ff 623 Gene3D G3DSA:3.90.550.10 2 264 4.1E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS12345 199dc3177bf6315c6e4a89f27688a715 276 SMART SM00530 14 69 5.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS12345 199dc3177bf6315c6e4a89f27688a715 276 SUPERFAMILY SSF47413 10 60 3.33E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS12345 199dc3177bf6315c6e4a89f27688a715 276 Pfam PF13560 Helix-turn-helix domain 11 55 9.9E-13 T 28-03-2018 CNX65_RS12345 199dc3177bf6315c6e4a89f27688a715 276 Gene3D G3DSA:1.10.10.60 10 37 1.2E-9 T 28-03-2018 CNX65_RS12345 199dc3177bf6315c6e4a89f27688a715 276 Gene3D G3DSA:1.10.260.40 38 81 1.3E-4 T 28-03-2018 CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 SUPERFAMILY SSF48498 80 181 4.2E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 SUPERFAMILY SSF46689 3 64 1.03E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 2.8E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 Gene3D G3DSA:1.10.10.60 1 53 1.6E-17 T 28-03-2018 CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 4.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 4.9E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 Gene3D G3DSA:1.10.357.10 54 180 2.1E-22 T 28-03-2018 CNX65_RS24095 dab9c51dccd67e26d77b9698ecd702e9 183 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 113 168 4.2E-8 T 28-03-2018 CNX65_RS06430 4cfa6f4c4072a219582243436f126035 647 Pfam PF13641 Glycosyltransferase like family 2 275 496 7.5E-39 T 28-03-2018 CNX65_RS06430 4cfa6f4c4072a219582243436f126035 647 Pfam PF01522 Polysaccharide deacetylase 46 108 3.4E-10 T 28-03-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 CNX65_RS06430 4cfa6f4c4072a219582243436f126035 647 SUPERFAMILY SSF88713 9 192 3.18E-18 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS06430 4cfa6f4c4072a219582243436f126035 647 SUPERFAMILY SSF53448 261 531 7.13E-63 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS06430 4cfa6f4c4072a219582243436f126035 647 Gene3D G3DSA:3.20.20.370 126 201 0.13 T 28-03-2018 CNX65_RS06430 4cfa6f4c4072a219582243436f126035 647 Gene3D G3DSA:3.90.550.10 251 516 5.9E-67 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS06430 4cfa6f4c4072a219582243436f126035 647 Gene3D G3DSA:3.20.20.370 26 125 1.4E-15 T 28-03-2018 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 Gene3D G3DSA:3.10.150.10 1 121 6.6E-21 T 28-03-2018 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 1 117 7.4E-18 T 28-03-2018 IPR022634 DNA polymerase III, beta chain, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 SMART SM00480 17 360 1.4E-28 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 SUPERFAMILY SSF55979 242 364 2.11E-16 T 28-03-2018 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 242 362 3.3E-16 T 28-03-2018 IPR022635 DNA polymerase III, beta chain, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 Gene3D G3DSA:3.10.150.10 245 365 1.4E-16 T 28-03-2018 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 Pfam PF02767 DNA polymerase III beta subunit, central domain 131 237 8.1E-14 T 28-03-2018 IPR022637 DNA polymerase III, beta chain, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 SUPERFAMILY SSF55979 1 118 8.52E-16 T 28-03-2018 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 SUPERFAMILY SSF55979 128 238 9.42E-11 T 28-03-2018 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 364 1.2E-44 T 28-03-2018 IPR001001 DNA polymerase III, beta chain GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS01185 65c7e04b49a20fc8943db2d0538aea94 365 Gene3D G3DSA:3.10.150.10 126 240 2.3E-22 T 28-03-2018 CNX65_RS01140 2281425fb1927ca81bc4b455f31d99fe 152 SUPERFAMILY SSF55298 2 150 2.04E-55 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS01140 2281425fb1927ca81bc4b455f31d99fe 152 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 6 150 8.9E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS01140 2281425fb1927ca81bc4b455f31d99fe 152 Gene3D G3DSA:3.30.1330.40 1 152 1.5E-34 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 9 195 1.6E-70 T 28-03-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00096 Glutamine amidotransferase superfamily signature 80 91 4.3E-8 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00096 Glutamine amidotransferase superfamily signature 169 182 4.3E-8 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00096 Glutamine amidotransferase superfamily signature 53 62 4.3E-8 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00097 Anthranilate synthase component II signature 53 62 1.1E-5 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00097 Anthranilate synthase component II signature 169 182 1.1E-5 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00097 Anthranilate synthase component II signature 80 91 1.1E-5 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 Gene3D G3DSA:3.40.50.620 214 393 3.6E-36 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 SUPERFAMILY SSF52317 8 229 2.22E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 6 519 53.828 T 28-03-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 Pfam PF00117 Glutamine amidotransferase class-I 11 192 1.1E-38 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 80 96 1.4E-5 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 9 23 1.4E-5 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 50 64 1.4E-5 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 SUPERFAMILY SSF54810 398 519 9.02E-47 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 205 519 3.8E-148 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 SUPERFAMILY SSF52402 185 439 1.19E-56 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 Gene3D G3DSA:3.40.50.880 4 213 1.3E-49 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 Gene3D G3DSA:3.30.300.10 394 519 1.4E-51 T 28-03-2018 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 Pfam PF00958 GMP synthase C terminal domain 426 518 1.2E-38 T 28-03-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 CNX65_RS32035 d9d2efb6ccfa6164cdfad7159a9f317a 519 Pfam PF02540 NAD synthase 216 251 1.5E-5 T 28-03-2018 IPR022310 NAD/GMP synthase CNX65_RS27955 b8d95ea3562df9585546083be07c598b 244 Pfam PF09534 Tryptophan-associated transmembrane protein (Trp_oprn_chp) 181 241 8.3E-17 T 28-03-2018 IPR019051 Trp biosynthesis associated, transmembrane protein, Oprn/Chp CNX65_RS26575 b67d38e0bb19222145a9c496d704a56e 343 SUPERFAMILY SSF50129 2 133 2.28E-24 T 28-03-2018 IPR011032 GroES-like CNX65_RS26575 b67d38e0bb19222145a9c496d704a56e 343 SUPERFAMILY SSF51735 164 285 8.14E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26575 b67d38e0bb19222145a9c496d704a56e 343 Gene3D G3DSA:3.90.180.10 2 174 1.6E-27 T 28-03-2018 CNX65_RS26575 b67d38e0bb19222145a9c496d704a56e 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 92 5.7E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS26575 b67d38e0bb19222145a9c496d704a56e 343 Gene3D G3DSA:3.40.50.720 175 284 2.1E-18 T 28-03-2018 CNX65_RS26575 b67d38e0bb19222145a9c496d704a56e 343 Pfam PF13602 Zinc-binding dehydrogenase 212 340 1.3E-19 T 28-03-2018 CNX65_RS26575 b67d38e0bb19222145a9c496d704a56e 343 SMART SM00829 10 340 3.2E-9 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS24955 495213f8b2af567cd960b4f957028cbd 214 Gene3D G3DSA:3.60.15.10 14 214 6.7E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS24955 495213f8b2af567cd960b4f957028cbd 214 SUPERFAMILY SSF56281 15 211 1.31E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS24955 495213f8b2af567cd960b4f957028cbd 214 SMART SM00849 14 204 5.5E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS24955 495213f8b2af567cd960b4f957028cbd 214 Pfam PF00753 Metallo-beta-lactamase superfamily 14 204 1.4E-28 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS33855 402e3f421a1e4f914dbd811d5683d834 255 SUPERFAMILY SSF52540 4 228 2.25E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS33855 402e3f421a1e4f914dbd811d5683d834 255 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS33855 402e3f421a1e4f914dbd811d5683d834 255 Gene3D G3DSA:3.40.50.300 1 249 1.3E-53 T 28-03-2018 CNX65_RS33855 402e3f421a1e4f914dbd811d5683d834 255 Pfam PF00005 ABC transporter 20 170 2.0E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS33855 402e3f421a1e4f914dbd811d5683d834 255 SMART SM00382 29 227 2.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Pfam PF00258 Flavodoxin 490 611 4.2E-15 T 28-03-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PIRSF PIRSF000209 3 1005 0.0 T 28-03-2018 IPR023206 Bifunctional cytochrome P450/NADPH--cytochrome P450 reductase GO:0003958|GO:0055114|GO:0070330 KEGG: 00071+1.14.14.1|KEGG: 00140+1.14.14.1|KEGG: 00232+1.14.14.1|KEGG: 00380+1.14.14.1|KEGG: 00590+1.14.14.1|KEGG: 00591+1.14.14.1|KEGG: 00627+1.14.14.1|KEGG: 00830+1.14.14.1|KEGG: 00980+1.14.14.1|KEGG: 00982+1.14.14.1|MetaCyc: PWY-5451|MetaCyc: PWY-5665|MetaCyc: PWY-6398|MetaCyc: PWY-6992|MetaCyc: PWY-7466|MetaCyc: PWY-7826 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 401 410 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Pfam PF00067 Cytochrome P450 9 452 2.1E-79 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Gene3D G3DSA:1.10.630.10 6 466 1.9E-116 T 28-03-2018 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00385 P450 superfamily signature 324 335 1.2E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00385 P450 superfamily signature 399 408 1.2E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00385 P450 superfamily signature 408 419 1.2E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00385 P450 superfamily signature 272 289 1.2E-10 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 SUPERFAMILY SSF52343 860 1005 2.1E-35 T 28-03-2018 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Gene3D G3DSA:2.40.30.10 656 854 4.9E-32 T 28-03-2018 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Gene3D G3DSA:3.40.50.80 858 1004 2.4E-25 T 28-03-2018 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 SUPERFAMILY SSF52218 485 636 4.19E-35 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 SUPERFAMILY SSF48264 7 460 1.3E-109 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Pfam PF00667 FAD binding domain 661 837 7.7E-16 T 28-03-2018 IPR003097 FAD-binding, type 1 GO:0016491|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00463 E-class P450 group I signature 398 408 3.4E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00463 E-class P450 group I signature 323 341 3.4E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00463 E-class P450 group I signature 408 431 3.4E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00463 E-class P450 group I signature 281 307 3.4E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00463 E-class P450 group I signature 261 278 3.4E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 PRINTS PR00463 E-class P450 group I signature 363 387 3.4E-25 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Pfam PF00175 Oxidoreductase NAD-binding domain 873 969 9.5E-10 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 SUPERFAMILY SSF63380 635 854 4.12E-45 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS16325 f884b5c2e0513caf0c047fbe0a7bb4b5 1005 Gene3D G3DSA:3.40.50.360 467 640 5.4E-29 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 SUPERFAMILY SSF51658 4 377 7.73E-108 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 Gene3D G3DSA:3.20.20.150 1 378 1.2E-83 T 28-03-2018 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 122 143 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 171 195 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 274 285 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 75 95 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 149 168 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 98 117 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 213 240 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 38 60 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 PRINTS PR00688 Xylose isomerase signature 241 252 1.8E-63 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 TIGRFAM TIGR02631 xylA_Arthro: xylose isomerase 3 376 1.0E-199 T 28-03-2018 IPR013453 Xylose isomerase, actinobacteria GO:0009045|GO:0042732 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 Hamap MF_00455 Xylose isomerase [xylA]. 1 375 32.781 T 28-03-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 CNX65_RS08955 11f310a2bc2d0e1d032ec90cf6b970e9 379 Pfam PF01261 Xylose isomerase-like TIM barrel 34 258 7.3E-27 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS20065 39b4f0e53848522e37300305ab354925 381 SUPERFAMILY SSF51735 50 173 8.44E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20065 39b4f0e53848522e37300305ab354925 381 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 52 138 2.5E-5 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS20065 39b4f0e53848522e37300305ab354925 381 SUPERFAMILY SSF55347 146 346 1.09E-32 T 28-03-2018 CNX65_RS20065 39b4f0e53848522e37300305ab354925 381 Gene3D G3DSA:3.40.50.720 1 153 8.1E-25 T 28-03-2018 CNX65_RS20065 39b4f0e53848522e37300305ab354925 381 Gene3D G3DSA:3.30.360.10 154 380 2.2E-40 T 28-03-2018 CNX65_RS20065 39b4f0e53848522e37300305ab354925 381 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 152 234 2.5E-4 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS07950 1452d21082d41ca43fa9b536d1792229 189 Gene3D G3DSA:1.10.357.10 55 189 1.4E-21 T 28-03-2018 CNX65_RS07950 1452d21082d41ca43fa9b536d1792229 189 SUPERFAMILY SSF46689 5 80 1.08E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS07950 1452d21082d41ca43fa9b536d1792229 189 SUPERFAMILY SSF48498 77 188 1.56E-16 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS07950 1452d21082d41ca43fa9b536d1792229 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS07950 1452d21082d41ca43fa9b536d1792229 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.5E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS07950 1452d21082d41ca43fa9b536d1792229 189 Gene3D G3DSA:1.10.10.60 2 54 3.3E-19 T 28-03-2018 CNX65_RS07950 1452d21082d41ca43fa9b536d1792229 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 2.5E-19 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34205 bca5de48748b8ea7c099dc13b688f9e7 299 SUPERFAMILY SSF53067 1 297 2.21E-51 T 28-03-2018 CNX65_RS34205 bca5de48748b8ea7c099dc13b688f9e7 299 Gene3D G3DSA:3.30.420.40 122 299 3.9E-45 T 28-03-2018 CNX65_RS34205 bca5de48748b8ea7c099dc13b688f9e7 299 Pfam PF00480 ROK family 2 294 5.9E-50 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS34205 bca5de48748b8ea7c099dc13b688f9e7 299 Gene3D G3DSA:3.30.420.40 1 121 8.3E-26 T 28-03-2018 CNX65_RS25400 1e4118c1278536675782790eb7726b69 163 Pfam PF03861 ANTAR domain 25 76 1.1E-15 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS25400 1e4118c1278536675782790eb7726b69 163 Gene3D G3DSA:1.10.10.10 25 77 2.3E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25400 1e4118c1278536675782790eb7726b69 163 Gene3D G3DSA:3.30.1020.10 85 137 0.0018 T 28-03-2018 CNX65_RS25400 1e4118c1278536675782790eb7726b69 163 SUPERFAMILY SSF52172 14 75 2.44E-5 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS25400 1e4118c1278536675782790eb7726b69 163 SMART SM01012 21 76 1.7E-16 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS03065 2ba57931aa65a33aead6602810eef658 432 Pfam PF01547 Bacterial extracellular solute-binding protein 70 345 8.0E-24 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS03065 2ba57931aa65a33aead6602810eef658 432 SUPERFAMILY SSF53850 35 430 3.83E-54 T 28-03-2018 CNX65_RS03065 2ba57931aa65a33aead6602810eef658 432 Gene3D G3DSA:3.40.190.10 46 164 1.6E-8 T 28-03-2018 CNX65_RS03065 2ba57931aa65a33aead6602810eef658 432 Gene3D G3DSA:3.40.190.10 165 379 4.5E-36 T 28-03-2018 CNX65_RS18935 f04a56f38b02a091f46a93942e6ecf1b 224 SUPERFAMILY SSF55729 94 216 7.44E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS18935 f04a56f38b02a091f46a93942e6ecf1b 224 Gene3D G3DSA:3.40.630.30 21 218 4.3E-20 T 28-03-2018 CNX65_RS18935 f04a56f38b02a091f46a93942e6ecf1b 224 Pfam PF08445 FR47-like protein 130 216 5.5E-24 T 28-03-2018 IPR013653 FR47-like GO:0016747 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 Pfam PF00672 HAMP domain 180 234 2.4E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 361 468 2.3E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 Pfam PF00512 His Kinase A (phospho-acceptor) domain 248 313 1.1E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 9.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 9.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 9.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 425 9.6E-17 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 SMART SM00304 180 239 1.8E-5 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 SUPERFAMILY SSF47384 235 313 5.1E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 SUPERFAMILY SSF55874 304 469 1.57E-42 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 Gene3D G3DSA:3.30.565.10 320 469 2.6E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 SMART SM00387 360 469 1.4E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 Gene3D G3DSA:1.10.287.130 237 310 1.8E-15 T 28-03-2018 CNX65_RS01940 09a4f0ebd0f1c23123fb7c1a5456ac96 469 SMART SM00388 247 314 1.4E-17 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PRINTS PR00471 Acetate kinase family signature 344 356 3.0E-30 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PRINTS PR00471 Acetate kinase family signature 270 283 3.0E-30 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PRINTS PR00471 Acetate kinase family signature 144 157 3.0E-30 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PRINTS PR00471 Acetate kinase family signature 174 195 3.0E-30 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PRINTS PR00471 Acetate kinase family signature 292 308 3.0E-30 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PRINTS PR00471 Acetate kinase family signature 4 15 3.0E-30 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 Gene3D G3DSA:3.30.420.40 3 166 2.4E-44 T 28-03-2018 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 174 191 - T 28-03-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 Gene3D G3DSA:3.30.420.40 167 363 2.4E-57 T 28-03-2018 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PIRSF PIRSF000722 37 363 1.4E-95 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 PIRSF PIRSF000722 1 44 0.19 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 SUPERFAMILY SSF53067 128 362 2.12E-64 T 28-03-2018 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 SUPERFAMILY SSF53067 3 166 5.83E-44 T 28-03-2018 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 Pfam PF00871 Acetokinase family 48 354 2.9E-85 T 28-03-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0008152|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS16965 783876a5e5fecc53919c19f00835bdfb 363 Hamap MF_00020 Acetate kinase [ackA]. 1 363 118.243 T 28-03-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 CNX65_RS15970 7701c2140a523a0b67aa5fdfe310e315 251 Pfam PF13649 Methyltransferase domain 52 144 8.6E-11 T 28-03-2018 CNX65_RS15970 7701c2140a523a0b67aa5fdfe310e315 251 SUPERFAMILY SSF53335 21 249 5.52E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS15970 7701c2140a523a0b67aa5fdfe310e315 251 Gene3D G3DSA:3.40.50.150 7 251 8.5E-29 T 28-03-2018 CNX65_RS11415 84c85644baf3b5f1d3fdbf7ea80992a5 197 Gene3D G3DSA:1.10.357.10 67 194 4.5E-9 T 28-03-2018 CNX65_RS11415 84c85644baf3b5f1d3fdbf7ea80992a5 197 SUPERFAMILY SSF46689 5 77 1.1E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS11415 84c85644baf3b5f1d3fdbf7ea80992a5 197 Gene3D G3DSA:1.10.260.40 45 66 3.6E-7 T 28-03-2018 CNX65_RS11415 84c85644baf3b5f1d3fdbf7ea80992a5 197 Gene3D G3DSA:1.10.10.60 1 44 2.1E-14 T 28-03-2018 CNX65_RS11415 84c85644baf3b5f1d3fdbf7ea80992a5 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 62 5.5E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11415 84c85644baf3b5f1d3fdbf7ea80992a5 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11415 84c85644baf3b5f1d3fdbf7ea80992a5 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 Pfam PF13183 4Fe-4S dicluster domain 296 412 8.3E-14 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 Gene3D G3DSA:1.20.950.20 5 246 1.2E-33 T 28-03-2018 CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 Pfam PF02754 Cysteine-rich domain 480 571 2.1E-14 T 28-03-2018 IPR004017 Cysteine-rich domain CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 Pfam PF02754 Cysteine-rich domain 610 696 1.1E-16 T 28-03-2018 IPR004017 Cysteine-rich domain CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 SUPERFAMILY SSF46548 379 426 4.36E-21 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 SUPERFAMILY SSF46548 282 320 4.36E-21 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 398 409 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS34355 fc38513a7c58e2f40f567001041b2d99 758 Gene3D G3DSA:1.10.1060.10 261 435 5.8E-32 T 28-03-2018 CNX65_RS27315 7709480f548275b3db09208e509dc993 239 SUPERFAMILY SSF55718 156 238 3.3E-13 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS27315 7709480f548275b3db09208e509dc993 239 Gene3D G3DSA:1.20.120.450 2 154 9.5E-25 T 28-03-2018 CNX65_RS27315 7709480f548275b3db09208e509dc993 239 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 11 222 7.9E-30 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS27315 7709480f548275b3db09208e509dc993 239 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 12 147 6.6E-26 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS27315 7709480f548275b3db09208e509dc993 239 SUPERFAMILY SSF109854 8 154 4.58E-40 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 ProSitePatterns PS00856 Guanylate kinase-like signature. 49 66 - T 28-03-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 Pfam PF00625 Guanylate kinase 15 191 1.5E-41 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 Gene3D G3DSA:3.40.50.300 11 57 3.3E-4 T 28-03-2018 CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 SUPERFAMILY SSF52540 14 193 8.89E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 Gene3D G3DSA:3.30.63.10 58 90 1.9E-25 T 28-03-2018 CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 Hamap MF_00328 Guanylate kinase [gmk]. 13 196 33.999 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 Gene3D G3DSA:3.40.50.300 91 193 6.5E-26 T 28-03-2018 CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 16 192 3.1E-65 T 28-03-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 CNX65_RS26070 b1c95a57dbec35943c13415589730a7f 199 SMART SM00072 14 196 7.1E-65 T 28-03-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 Gene3D G3DSA:3.40.50.720 37 241 5.3E-42 T 28-03-2018 CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 Gene3D G3DSA:3.40.50.720 1 36 2.6E-8 T 28-03-2018 CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 Pfam PF00106 short chain dehydrogenase 5 186 4.6E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 1.0E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 1.0E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 1.0E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 1.0E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 1.0E-20 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS33315 ad747e0152363c8c5c2116dc2875cf9d 243 SUPERFAMILY SSF51735 3 231 8.95E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12380 1ce4f5a45a21612b6611be8c11587ec9 405 PIRSF PIRSF033091 1 404 1.6E-93 T 28-03-2018 IPR014576 Predicted phosphoesterase, YhaO type CNX65_RS12380 1ce4f5a45a21612b6611be8c11587ec9 405 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 233 1.4E-13 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CNX65_RS12380 1ce4f5a45a21612b6611be8c11587ec9 405 SUPERFAMILY SSF56300 1 278 1.22E-48 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS12380 1ce4f5a45a21612b6611be8c11587ec9 405 Gene3D G3DSA:3.60.21.10 1 78 8.6E-11 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS12380 1ce4f5a45a21612b6611be8c11587ec9 405 Gene3D G3DSA:3.60.21.10 79 249 3.1E-15 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS20045 36dd080dae3377260e615681aaa060a5 396 Gene3D G3DSA:3.50.50.60 2 371 1.7E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20045 36dd080dae3377260e615681aaa060a5 396 Pfam PF01494 FAD binding domain 2 321 1.5E-17 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS20045 36dd080dae3377260e615681aaa060a5 396 SUPERFAMILY SSF51905 268 366 4.88E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20045 36dd080dae3377260e615681aaa060a5 396 SUPERFAMILY SSF51905 2 168 4.88E-51 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20045 36dd080dae3377260e615681aaa060a5 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 5.2E-11 T 28-03-2018 CNX65_RS20045 36dd080dae3377260e615681aaa060a5 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 5.2E-11 T 28-03-2018 CNX65_RS20045 36dd080dae3377260e615681aaa060a5 396 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 281 296 5.2E-11 T 28-03-2018 CNX65_RS08040 ff70cf459816e0260281c83a6fbd516c 385 Gene3D G3DSA:1.10.443.10 179 375 1.6E-34 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS08040 ff70cf459816e0260281c83a6fbd516c 385 SUPERFAMILY SSF56349 72 375 8.54E-56 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS08040 ff70cf459816e0260281c83a6fbd516c 385 Pfam PF00589 Phage integrase family 177 365 4.5E-20 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS08040 ff70cf459816e0260281c83a6fbd516c 385 Gene3D G3DSA:1.10.150.130 66 178 3.6E-18 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 SUPERFAMILY SSF46785 4 108 1.25E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 65 5.9E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 Pfam PF03466 LysR substrate binding domain 91 292 4.3E-23 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 SUPERFAMILY SSF53850 94 299 5.84E-20 T 28-03-2018 CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 42 53 4.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 32 42 4.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 21 32 4.0E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 Gene3D G3DSA:3.40.190.10 184 269 1.4E-15 T 28-03-2018 CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 Gene3D G3DSA:3.40.190.10 91 183 2.4E-12 T 28-03-2018 CNX65_RS02805 3a2b1e57505128e8689b0eff35b85f98 329 Gene3D G3DSA:1.10.10.10 1 83 1.7E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25440 c0fc8063b59ece99511f489a7af07539 316 TIGRFAM TIGR03841 F420_Rv3093c: probable F420-dependent oxidoreductase, Rv3093c family 12 296 3.9E-95 T 28-03-2018 IPR022526 F420-dependent oxidoreductase, Rv3093c CNX65_RS25440 c0fc8063b59ece99511f489a7af07539 316 Pfam PF00296 Luciferase-like monooxygenase 25 292 7.1E-54 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS25440 c0fc8063b59ece99511f489a7af07539 316 Gene3D G3DSA:3.20.20.30 3 314 1.8E-53 T 28-03-2018 CNX65_RS25440 c0fc8063b59ece99511f489a7af07539 316 SUPERFAMILY SSF51679 7 313 1.77E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 SUPERFAMILY SSF49384 28 129 1.67E-29 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 Pfam PF00041 Fibronectin type III domain 143 213 3.3E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 SMART SM00637 31 128 1.2E-34 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 Gene3D G3DSA:2.60.40.290 22 128 8.0E-32 T 28-03-2018 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 SUPERFAMILY SSF51445 274 525 9.32E-18 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 Gene3D G3DSA:3.20.20.80 270 545 1.3E-22 T 28-03-2018 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 Pfam PF00553 Cellulose binding domain 32 128 1.9E-27 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 Gene3D G3DSA:2.60.40.10 135 224 2.0E-17 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 SUPERFAMILY SSF49265 140 231 4.87E-15 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS30705 41768224c743f638c4a01db6ccbe9717 552 SMART SM00060 142 215 9.7E-12 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS10615 e2922db6a8236b3af3fd97421913b8cc 452 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 228 235 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS10615 e2922db6a8236b3af3fd97421913b8cc 452 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 256 267 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS10615 e2922db6a8236b3af3fd97421913b8cc 452 Pfam PF00171 Aldehyde dehydrogenase family 4 448 9.4E-159 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS10615 e2922db6a8236b3af3fd97421913b8cc 452 Gene3D G3DSA:3.40.309.10 247 434 4.1E-66 T 28-03-2018 CNX65_RS10615 e2922db6a8236b3af3fd97421913b8cc 452 SUPERFAMILY SSF53720 4 450 7.98E-155 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS10615 e2922db6a8236b3af3fd97421913b8cc 452 Gene3D G3DSA:3.40.605.10 2 246 1.1E-91 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS23150 1b91ce9066df5c3338cd530ac99169bf 364 SUPERFAMILY SSF53756 2 360 1.22E-50 T 28-03-2018 CNX65_RS23150 1b91ce9066df5c3338cd530ac99169bf 364 Gene3D G3DSA:3.40.50.2000 199 353 2.0E-29 T 28-03-2018 CNX65_RS23150 1b91ce9066df5c3338cd530ac99169bf 364 Pfam PF00534 Glycosyl transferases group 1 246 340 4.1E-18 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS23150 1b91ce9066df5c3338cd530ac99169bf 364 Gene3D G3DSA:3.40.50.2000 1 198 8.3E-4 T 28-03-2018 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 Gene3D G3DSA:3.30.479.20 53 148 3.3E-15 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 Pfam PF00889 Elongation factor TS 67 270 9.3E-62 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 SUPERFAMILY SSF46934 3 56 3.06E-16 T 28-03-2018 IPR009060 UBA-like GO:0005515 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 Gene3D G3DSA:1.10.8.10 1 52 2.8E-20 T 28-03-2018 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 Hamap MF_00050 Elongation factor Ts [tsf]. 1 271 65.588 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 Gene3D G3DSA:3.30.479.20 224 269 1.8E-12 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 Gene3D G3DSA:3.30.479.20 149 201 3.1E-8 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 Gene3D G3DSA:1.10.286.20 202 223 5.8E-16 T 28-03-2018 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 270 6.4E-78 T 28-03-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 SUPERFAMILY SSF54713 58 88 5.72E-41 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS29000 9955b0e24cbed32f2a8f2314b11ec04f 271 SUPERFAMILY SSF54713 173 269 5.72E-41 T 28-03-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 CNX65_RS02810 f647fbcc4f1a10462cf814860a8270cd 271 Gene3D G3DSA:3.40.50.720 1 205 1.1E-21 T 28-03-2018 CNX65_RS02810 f647fbcc4f1a10462cf814860a8270cd 271 SUPERFAMILY SSF51735 3 218 8.55E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02810 f647fbcc4f1a10462cf814860a8270cd 271 Pfam PF05368 NmrA-like family 4 157 6.8E-18 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 SMART SM00930 251 324 5.3E-8 T 28-03-2018 IPR018449 NIL domain CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 Pfam PF00005 ABC transporter 18 166 1.6E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 SUPERFAMILY SSF55021 250 321 3.32E-7 T 28-03-2018 CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 Gene3D G3DSA:3.40.50.300 1 242 2.3E-75 T 28-03-2018 CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 SMART SM00382 27 223 6.4E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 SUPERFAMILY SSF52540 1 231 4.22E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 Gene3D G3DSA:3.30.70.260 243 325 2.5E-9 T 28-03-2018 CNX65_RS03190 a36edfa7ba3434191ed22b80ea1c67e0 333 Pfam PF09383 NIL domain 256 318 4.5E-7 T 28-03-2018 IPR018449 NIL domain CNX65_RS30445 057230b47cf2f615b4a2e48ffba3eb5e 126 Gene3D G3DSA:3.10.180.10 1 126 1.2E-13 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS30445 057230b47cf2f615b4a2e48ffba3eb5e 126 SUPERFAMILY SSF54593 13 112 2.97E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS25330 f48d8ee9db0b22022c74a37de75d8834 160 SUPERFAMILY SSF55729 2 131 9.26E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS25330 f48d8ee9db0b22022c74a37de75d8834 160 Pfam PF00583 Acetyltransferase (GNAT) family 49 126 1.7E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS25330 f48d8ee9db0b22022c74a37de75d8834 160 Gene3D G3DSA:3.40.630.30 1 146 2.7E-18 T 28-03-2018 CNX65_RS08985 1fdc93e4e6e8caee22e3beb42ad8cfc8 247 SUPERFAMILY SSF56300 2 224 3.53E-30 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS08985 1fdc93e4e6e8caee22e3beb42ad8cfc8 247 Pfam PF00149 Calcineurin-like phosphoesterase 2 204 5.0E-10 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS08985 1fdc93e4e6e8caee22e3beb42ad8cfc8 247 Gene3D G3DSA:3.60.21.10 1 244 4.8E-27 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS08985 1fdc93e4e6e8caee22e3beb42ad8cfc8 247 PIRSF PIRSF008292 1 235 5.3E-90 T 28-03-2018 IPR016538 Uncharacterised conserved protein UCP008292 CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 Pfam PF00069 Protein kinase domain 12 264 8.7E-50 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 Gene3D G3DSA:1.10.510.10 99 441 2.4E-48 T 28-03-2018 CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 135 147 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 Gene3D G3DSA:3.30.200.20 1 98 5.5E-24 T 28-03-2018 CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 SUPERFAMILY SSF56112 366 451 1.48E-76 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 SUPERFAMILY SSF56112 8 270 1.48E-76 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 SMART SM00220 12 267 2.2E-61 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 18 41 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS31990 388e292f4736a73ca5e34d651a987044 466 PIRSF PIRSF000654 15 276 3.8E-22 T 28-03-2018 CNX65_RS25985 3b317f810a0fcad564c6ffbc6173bf85 168 Gene3D G3DSA:3.40.50.1950 7 166 2.2E-23 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CNX65_RS25985 3b317f810a0fcad564c6ffbc6173bf85 168 Pfam PF02441 Flavoprotein 16 150 1.0E-11 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CNX65_RS25985 3b317f810a0fcad564c6ffbc6173bf85 168 SUPERFAMILY SSF52507 14 152 7.33E-20 T 28-03-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 PRINTS PR01398 Isochorismatase signature 61 78 2.8E-33 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 PRINTS PR01398 Isochorismatase signature 188 205 2.8E-33 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 PRINTS PR01398 Isochorismatase signature 78 97 2.8E-33 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 PRINTS PR01398 Isochorismatase signature 2 14 2.8E-33 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 PRINTS PR01398 Isochorismatase signature 170 188 2.8E-33 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 Pfam PF00857 Isochorismatase family 32 207 3.0E-40 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 SUPERFAMILY SSF52499 2 212 9.29E-62 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS13815 aad78a91924b056e9690bc52063a1f98 222 Gene3D G3DSA:3.40.50.850 1 213 1.6E-49 T 28-03-2018 CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 Pfam PF00005 ABC transporter 21 172 1.1E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 Pfam PF00005 ABC transporter 279 434 5.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 SUPERFAMILY SSF52540 246 493 8.88E-44 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 Gene3D G3DSA:3.40.50.300 1 235 5.3E-50 T 28-03-2018 CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 ProSitePatterns PS00211 ABC transporters family signature. 407 421 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 SUPERFAMILY SSF52540 5 233 6.5E-54 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 Gene3D G3DSA:3.40.50.300 254 507 1.7E-38 T 28-03-2018 CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 SMART SM00382 30 220 6.9E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS09315 1c983ef939e4d1301d000ce1fe3ded10 508 SMART SM00382 287 482 4.3E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 SUPERFAMILY SSF52540 405 617 1.28E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 SUPERFAMILY SSF90123 32 339 2.88E-58 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 ProSitePatterns PS00211 ABC transporters family signature. 529 543 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 Pfam PF00005 ABC transporter 410 556 1.9E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 Pfam PF00664 ABC transporter transmembrane region 44 314 4.3E-28 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 Gene3D G3DSA:3.40.50.300 346 628 2.3E-60 T 28-03-2018 CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 Gene3D G3DSA:1.20.1560.10 24 345 2.1E-54 T 28-03-2018 CNX65_RS18395 e7dd709faa084220ce8c3f8184720c8e 632 SMART SM00382 419 603 1.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18585 17e8f070dfd13df1d3c718abd2bf010d 286 Pfam PF02558 Ketopantoate reductase PanE/ApbA 4 119 5.1E-15 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CNX65_RS18585 17e8f070dfd13df1d3c718abd2bf010d 286 Gene3D G3DSA:3.40.50.720 1 177 1.8E-16 T 28-03-2018 CNX65_RS18585 17e8f070dfd13df1d3c718abd2bf010d 286 SUPERFAMILY SSF51735 2 133 3.02E-7 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07625 0140968d9810f95d3562ed4020596482 228 Gene3D G3DSA:1.10.10.10 2 68 5.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 SUPERFAMILY SSF52540 750 796 1.15E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 SUPERFAMILY SSF52540 30 209 1.15E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 SUPERFAMILY SSF52540 241 512 1.15E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 SUPERFAMILY SSF52540 552 702 1.15E-106 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Gene3D G3DSA:3.40.50.300 25 361 1.4E-45 T 28-03-2018 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Pfam PF13361 UvrD-like helicase C-terminal domain 396 506 3.8E-7 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Pfam PF13361 UvrD-like helicase C-terminal domain 618 771 1.7E-15 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Gene3D G3DSA:3.90.320.10 690 1315 9.8E-17 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Gene3D G3DSA:3.40.50.300 362 471 1.1E-9 T 28-03-2018 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1166 1314 3.2E-11 T 28-03-2018 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 SUPERFAMILY SSF52980 1149 1303 1.07E-6 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Pfam PF00580 UvrD/REP helicase N-terminal domain 34 351 2.7E-47 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CNX65_RS04195 f40d4781104cf0bac346582f39f6feb1 1345 Gene3D G3DSA:1.10.486.10 472 648 8.2E-29 T 28-03-2018 CNX65_RS04060 ac765a979fb9d9a6cde8e9e9738ab92b 497 Gene3D G3DSA:2.140.10.10 123 320 1.4E-14 T 28-03-2018 CNX65_RS04060 ac765a979fb9d9a6cde8e9e9738ab92b 497 Gene3D G3DSA:2.140.10.10 321 494 1.4E-6 T 28-03-2018 CNX65_RS04060 ac765a979fb9d9a6cde8e9e9738ab92b 497 Pfam PF13360 PQQ-like domain 154 258 2.7E-4 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CNX65_RS04060 ac765a979fb9d9a6cde8e9e9738ab92b 497 SUPERFAMILY SSF50998 286 483 5.23E-10 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS04060 ac765a979fb9d9a6cde8e9e9738ab92b 497 SUPERFAMILY SSF50998 152 208 5.23E-10 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS04305 44c68467c969508d9dccba4ae005f134 315 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 9 267 1.2E-52 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CNX65_RS04305 44c68467c969508d9dccba4ae005f134 315 Pfam PF03186 CobD/Cbib protein 9 290 7.6E-91 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CNX65_RS04305 44c68467c969508d9dccba4ae005f134 315 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 312 90.582 T 28-03-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 CNX65_RS01680 3aa65d1e5977b310b483a37e6d426b5c 261 Pfam PF03309 Type III pantothenate kinase 2 208 3.8E-62 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CNX65_RS01680 3aa65d1e5977b310b483a37e6d426b5c 261 Gene3D G3DSA:3.30.420.40 98 261 6.9E-54 T 28-03-2018 CNX65_RS01680 3aa65d1e5977b310b483a37e6d426b5c 261 Gene3D G3DSA:3.30.420.40 1 97 4.0E-5 T 28-03-2018 CNX65_RS01680 3aa65d1e5977b310b483a37e6d426b5c 261 SUPERFAMILY SSF53067 2 123 6.2E-27 T 28-03-2018 CNX65_RS01680 3aa65d1e5977b310b483a37e6d426b5c 261 SUPERFAMILY SSF53067 126 259 3.89E-34 T 28-03-2018 CNX65_RS01680 3aa65d1e5977b310b483a37e6d426b5c 261 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 2 256 5.1E-72 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CNX65_RS01680 3aa65d1e5977b310b483a37e6d426b5c 261 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 260 33.145 T 28-03-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 CNX65_RS28480 2b9681207e1341c43ae0f500d01e48cc 250 TIGRFAM TIGR02170 thyX: thymidylate synthase, flavin-dependent 8 230 4.4E-59 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CNX65_RS28480 2b9681207e1341c43ae0f500d01e48cc 250 Pfam PF02511 Thymidylate synthase complementing protein 31 224 9.4E-55 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CNX65_RS28480 2b9681207e1341c43ae0f500d01e48cc 250 Hamap MF_01408 Flavin-dependent thymidylate synthase [thyX]. 5 238 26.594 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CNX65_RS28480 2b9681207e1341c43ae0f500d01e48cc 250 SUPERFAMILY SSF69796 28 235 1.44E-61 T 28-03-2018 IPR003669 Thymidylate synthase ThyX GO:0006231|GO:0050660|GO:0050797 KEGG: 00240+2.1.1.148|KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|KEGG: 00670+2.1.1.148|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6545|MetaCyc: PWY-6936|MetaCyc: PWY-702 CNX65_RS33795 ff1e631dd6c3a256bf25df12b705e7a7 126 SUPERFAMILY SSF46785 1 120 8.07E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33795 ff1e631dd6c3a256bf25df12b705e7a7 126 Pfam PF01475 Ferric uptake regulator family 1 113 3.5E-22 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CNX65_RS33795 ff1e631dd6c3a256bf25df12b705e7a7 126 Gene3D G3DSA:1.10.10.10 1 75 1.9E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 Gene3D G3DSA:3.90.180.10 6 174 3.3E-46 T 28-03-2018 CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 Gene3D G3DSA:3.40.50.10730 175 303 4.5E-37 T 28-03-2018 CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 SUPERFAMILY SSF50129 310 360 5.18E-8 T 28-03-2018 IPR011032 GroES-like CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 SMART SM00829 14 359 6.8E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 148 5.1E-28 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 Pfam PF00107 Zinc-binding dehydrogenase 190 317 1.9E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 SUPERFAMILY SSF51735 154 326 7.79E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 5 361 2.0E-207 T 28-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS18860 bbec65761ae0b3604679dc68ca58956f 361 SUPERFAMILY SSF50129 3 186 4.72E-55 T 28-03-2018 IPR011032 GroES-like CNX65_RS05585 e9bf09576959605bacdeac622fad87a0 687 Pfam PF05425 Copper resistance protein D 223 319 2.0E-17 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CNX65_RS05585 e9bf09576959605bacdeac622fad87a0 687 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 371 616 9.8E-87 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 SUPERFAMILY SSF55681 13 222 4.39E-62 T 28-03-2018 CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 ProSitePatterns PS01313 Lipoate-protein ligase B signature. 81 96 - T 28-03-2018 IPR020605 Octanoyltransferase, conserved site GO:0005737|GO:0009107|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 Pfam PF03099 Biotin/lipoate A/B protein ligase family 71 172 3.9E-9 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 Hamap MF_00013 Octanoyltransferase [lipB]. 14 222 33.162 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 ProDom PD006086 LIGASE LIPOATE-PROTEIN B TRANSFERASE ACYLTRANSFERASE LIPOYLTRANSFERASE LIPOYL-ACYL-CARRIER 2.3.1.- PROTEIN-PROTEIN- N-LIPOYLTRANSFERASE 85 137 3.0E-18 T 28-03-2018 CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 Gene3D G3DSA:3.30.930.10 8 220 8.3E-67 T 28-03-2018 CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 PIRSF PIRSF016262 11 226 4.7E-59 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CNX65_RS06645 9d469970fd5741c0787ad78feaa8bcdd 247 TIGRFAM TIGR00214 lipB: lipoyl(octanoyl) transferase 40 208 6.5E-40 T 28-03-2018 IPR000544 Octanoyltransferase GO:0005737|GO:0009107|GO:0033819 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CNX65_RS03060 bcb2e1fc56288c2f9c88ced03d275aa9 305 SUPERFAMILY SSF161098 68 290 3.14E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03060 bcb2e1fc56288c2f9c88ced03d275aa9 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 100 300 1.2E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03060 bcb2e1fc56288c2f9c88ced03d275aa9 305 Gene3D G3DSA:1.10.3720.10 21 304 9.0E-46 T 28-03-2018 CNX65_RS35065 23d440a98cd3346374c832ecbfdb6f66 358 Pfam PF02096 60Kd inner membrane protein 32 251 5.5E-51 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CNX65_RS35065 23d440a98cd3346374c832ecbfdb6f66 358 Gene3D G3DSA:1.20.1110.10 28 251 0.0013 T 28-03-2018 CNX65_RS35065 23d440a98cd3346374c832ecbfdb6f66 358 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 32 250 2.0E-56 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 SUPERFAMILY SSF81653 98 186 3.01E-20 T 28-03-2018 IPR008250 P-type ATPase, A domain Reactome: R-HSA-936837 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 Pfam PF00122 E1-E2 ATPase 97 262 1.2E-34 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 Gene3D G3DSA:3.40.1110.10 291 447 7.0E-26 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 286 292 - T 28-03-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 Pfam PF00702 haloacid dehalogenase-like hydrolase 280 501 7.9E-34 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 SUPERFAMILY SSF81665 21 89 3.14E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 SUPERFAMILY SSF81665 187 278 3.14E-13 T 28-03-2018 IPR023298 P-type ATPase, transmembrane domain Reactome: R-HSA-936837 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 TIGRFAM TIGR01497 kdpB: K+-transporting ATPase, B subunit 6 647 5.5E-297 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 Gene3D G3DSA:2.70.150.10 18 187 9.7E-26 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 348 570 5.5E-47 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 58 305 3.1E-33 T 28-03-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 284 298 7.6E-26 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 510 522 7.6E-26 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 434 444 7.6E-26 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 133 147 7.6E-26 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 487 506 7.6E-26 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 412 423 7.6E-26 T 28-03-2018 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 SUPERFAMILY SSF56784 384 537 1.86E-38 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 SUPERFAMILY SSF56784 283 302 1.86E-38 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 Hamap MF_00285 Potassium-transporting ATPase ATP-binding subunit [kdpB]. 1 651 39.533 T 28-03-2018 IPR006391 P-type ATPase, B chain, subfamily IA GO:0005524|GO:0006813|GO:0008556|GO:0016021 CNX65_RS16470 36f0a2a1b55447b31a5547b080fedee5 654 Gene3D G3DSA:1.20.1110.10 448 649 3.7E-30 T 28-03-2018 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 Pfam PF00108 Thiolase, N-terminal domain 7 273 2.1E-45 T 28-03-2018 IPR020616 Thiolase, N-terminal GO:0008152|GO:0016747 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 SUPERFAMILY SSF53901 7 280 1.89E-55 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 Pfam PF02803 Thiolase, C-terminal domain 301 421 2.4E-28 T 28-03-2018 IPR020617 Thiolase, C-terminal GO:0008152|GO:0016747 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 9 420 2.5E-112 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 Gene3D G3DSA:3.40.47.10 277 419 3.9E-24 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 SUPERFAMILY SSF53901 301 421 1.42E-29 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 Gene3D G3DSA:3.40.47.10 2 276 2.3E-36 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS34460 d552d3a3257bbaf0f956429bb48c0f48 421 PIRSF PIRSF000429 2 421 8.5E-99 T 28-03-2018 IPR002155 Thiolase GO:0008152|GO:0016747 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 43 1.2E-15 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 SUPERFAMILY SSF47413 1 56 8.44E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 Gene3D G3DSA:1.10.260.40 1 52 1.7E-19 T 28-03-2018 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 Pfam PF13377 Periplasmic binding protein-like domain 164 312 3.5E-29 T 28-03-2018 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 Gene3D G3DSA:3.40.50.2300 53 173 4.5E-38 T 28-03-2018 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 SUPERFAMILY SSF53822 58 313 3.14E-54 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 Gene3D G3DSA:3.40.50.2300 174 315 2.1E-29 T 28-03-2018 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 SMART SM00354 1 68 1.2E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS34245 2b1673d08e5b4dc4db2926f8eef22902 315 ProSitePatterns PS00356 LacI-type HTH domain signature. 1 19 - T 28-03-2018 CNX65_RS20715 86d83e6e237a40012e92793de91ce05f 267 SUPERFAMILY SSF81606 12 266 1.99E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS20715 86d83e6e237a40012e92793de91ce05f 267 Gene3D G3DSA:3.60.40.10 3 267 1.1E-5 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS20715 86d83e6e237a40012e92793de91ce05f 267 Pfam PF13672 Protein phosphatase 2C 16 245 2.2E-7 T 28-03-2018 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 Gene3D G3DSA:1.20.140.10 220 380 9.7E-46 T 28-03-2018 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 120 5.2E-27 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 SUPERFAMILY SSF56645 4 243 1.57E-76 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 379 5.0E-39 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 SUPERFAMILY SSF47203 229 379 4.67E-43 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 Gene3D G3DSA:2.40.110.10 125 219 3.2E-37 T 28-03-2018 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 219 1.1E-25 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 Gene3D G3DSA:1.10.540.10 3 124 1.7E-30 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS07925 2e2d5daa43cf9af875ceeb2abc25165b 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 338 357 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS23700 8dfd6b96d9f05c1d2d53326aabd819c8 377 Gene3D G3DSA:3.30.1220.10 238 344 7.4E-29 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS23700 8dfd6b96d9f05c1d2d53326aabd819c8 377 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 10 209 1.3E-57 T 28-03-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain CNX65_RS23700 8dfd6b96d9f05c1d2d53326aabd819c8 377 Gene3D G3DSA:3.40.50.300 6 228 1.1E-53 T 28-03-2018 CNX65_RS23700 8dfd6b96d9f05c1d2d53326aabd819c8 377 SMART SM00833 255 344 5.0E-27 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS23700 8dfd6b96d9f05c1d2d53326aabd819c8 377 SUPERFAMILY SSF52540 7 315 8.68E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23700 8dfd6b96d9f05c1d2d53326aabd819c8 377 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 255 341 8.4E-22 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 73 1.4E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 Gene3D G3DSA:1.10.10.10 2 75 4.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 Pfam PF07702 UTRA domain 94 223 1.5E-19 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 SMART SM00345 14 73 3.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 SMART SM00866 91 230 1.2E-14 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 Gene3D G3DSA:3.40.1410.10 86 233 6.2E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 SUPERFAMILY SSF64288 61 235 5.34E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS10215 15916209c1601f9eec0b8b7fb9329a1d 240 SUPERFAMILY SSF46785 1 83 3.63E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11095 934fa235d0dad9c0f9adfbae0522d36a 646 Gene3D G3DSA:2.60.40.1180 553 636 4.4E-31 T 28-03-2018 CNX65_RS11095 934fa235d0dad9c0f9adfbae0522d36a 646 Gene3D G3DSA:1.50.10.10 144 552 1.0E-108 T 28-03-2018 CNX65_RS11095 934fa235d0dad9c0f9adfbae0522d36a 646 Gene3D G3DSA:2.70.98.50 9 134 2.2E-23 T 28-03-2018 CNX65_RS11095 934fa235d0dad9c0f9adfbae0522d36a 646 SUPERFAMILY SSF48208 190 613 1.36E-70 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS11095 934fa235d0dad9c0f9adfbae0522d36a 646 Pfam PF14498 Glycosyl hydrolase family 65, N-terminal domain 10 126 7.4E-23 T 28-03-2018 IPR027414 Glycosyl hydrolase family 95, N-terminal domain KEGG: 00511+3.2.1.51 CNX65_RS08625 2f17396c56a440cdc8ca7d03a64f45c5 248 Pfam PF05331 Protein of unknown function (DUF742) 143 248 3.9E-31 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CNX65_RS28885 bfeb04352e102f56a53952875137ce83 283 Gene3D G3DSA:3.40.630.30 138 282 2.0E-19 T 28-03-2018 CNX65_RS28885 bfeb04352e102f56a53952875137ce83 283 SUPERFAMILY SSF55729 86 278 3.24E-18 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS28885 bfeb04352e102f56a53952875137ce83 283 Pfam PF13312 Domain of unknown function (DUF4081) 47 155 3.5E-41 T 28-03-2018 IPR025289 Domain of unknown function DUF4081 CNX65_RS28885 bfeb04352e102f56a53952875137ce83 283 Pfam PF08445 FR47-like protein 211 276 4.2E-10 T 28-03-2018 IPR013653 FR47-like GO:0016747 CNX65_RS28885 bfeb04352e102f56a53952875137ce83 283 PIRSF PIRSF021603 2 283 5.2E-116 T 28-03-2018 IPR016794 Uncharacterised conserved protein UCP21603, acetyltransferase-like CNX65_RS07635 902443450ea0b421557e085e1fe0c6a9 94 Gene3D G3DSA:3.40.1620.10 4 81 1.3E-14 T 28-03-2018 CNX65_RS07635 902443450ea0b421557e085e1fe0c6a9 94 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 6 42 1.3E-7 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS07635 902443450ea0b421557e085e1fe0c6a9 94 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 7 44 2.5E-9 T 28-03-2018 CNX65_RS07635 902443450ea0b421557e085e1fe0c6a9 94 SUPERFAMILY SSF143120 6 45 6.54E-8 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS31110 669d76eee97de3b5a0eb3470884b6ca7 305 Pfam PF01545 Cation efflux family 10 212 4.9E-32 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CNX65_RS31110 669d76eee97de3b5a0eb3470884b6ca7 305 Gene3D G3DSA:1.20.1510.10 6 217 1.7E-31 T 28-03-2018 CNX65_RS31110 669d76eee97de3b5a0eb3470884b6ca7 305 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 8 288 3.3E-38 T 28-03-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 CNX65_RS31110 669d76eee97de3b5a0eb3470884b6ca7 305 Gene3D G3DSA:3.30.70.1350 218 303 9.8E-7 T 28-03-2018 IPR027470 Cation efflux protein, cytoplasmic domain CNX65_RS31110 669d76eee97de3b5a0eb3470884b6ca7 305 SUPERFAMILY SSF161111 6 219 9.02E-36 T 28-03-2018 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 SUPERFAMILY SSF102114 161 393 1.83E-45 T 28-03-2018 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 Gene3D G3DSA:3.80.30.20 171 403 1.4E-39 T 28-03-2018 IPR023404 Radical SAM, alpha/beta horseshoe CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 Pfam PF04055 Radical SAM superfamily 176 347 1.1E-22 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 TIGRFAM TIGR01125 TIGR01125: ribosomal protein S12 methylthiotransferase RimO 12 463 7.8E-119 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 174 194 - T 28-03-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 Pfam PF00919 Uncharacterized protein family UPF0004 12 104 4.7E-27 T 28-03-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 12 462 9.1E-100 T 28-03-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 SMART SM00729 170 389 8.2E-40 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 Gene3D G3DSA:2.40.50.140 404 469 3.3E-18 T 28-03-2018 CNX65_RS28425 5da3b76000623c169881fea9352c4ef5 472 Hamap MF_01865 Ribosomal protein S12 methylthiotransferase RimO [rimO]. 11 466 56.773 T 28-03-2018 IPR005840 Ribosomal protein S12 methylthiotransferase RimO GO:0005737|GO:0016740|GO:0018339|GO:0051539 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Gene3D G3DSA:3.30.300.50 33 109 2.8E-20 T 28-03-2018 IPR035070 Streptogrisin prodomain CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 306 329 2.5E-39 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 330 344 2.5E-39 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 266 286 2.5E-39 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 206 220 2.5E-39 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 287 304 2.5E-39 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Gene3D G3DSA:2.80.10.50 415 495 3.4E-20 T 28-03-2018 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 SUPERFAMILY SSF50494 189 358 1.42E-32 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Gene3D G3DSA:3.30.300.50 110 174 2.9E-15 T 28-03-2018 IPR035070 Streptogrisin prodomain CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 SUPERFAMILY SSF50370 370 494 1.02E-33 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Gene3D G3DSA:2.40.10.10 183 261 2.1E-19 T 28-03-2018 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Pfam PF00652 Ricin-type beta-trefoil lectin domain 379 493 2.7E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 SMART SM00458 371 496 1.8E-26 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Gene3D G3DSA:2.40.10.10 262 352 6.7E-16 T 28-03-2018 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Gene3D G3DSA:2.80.10.50 367 414 1.2E-9 T 28-03-2018 CNX65_RS09240 79e9497534a5c37e60698ad174b028bb 496 Pfam PF02983 Alpha-lytic protease prodomain 112 166 8.4E-16 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 SUPERFAMILY SSF88659 118 191 1.07E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 SUPERFAMILY SSF88946 37 111 2.94E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 37 190 1.4E-47 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 Gene3D G3DSA:1.10.1740.10 34 104 7.4E-14 T 28-03-2018 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 Pfam PF08281 Sigma-70, region 4 133 185 2.1E-19 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 Pfam PF04542 Sigma-70 region 2 40 106 7.2E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 188 3.1E-25 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34200 08246e4a3134b7453da09764b04d0076 192 Gene3D G3DSA:1.10.10.10 105 192 1.8E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02525 a2f5efa22b484dd92ced39bf31e0adf1 260 SUPERFAMILY SSF55315 6 101 2.21E-11 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS02525 a2f5efa22b484dd92ced39bf31e0adf1 260 Gene3D G3DSA:3.40.1280.10 101 260 2.7E-43 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CNX65_RS02525 a2f5efa22b484dd92ced39bf31e0adf1 260 Gene3D G3DSA:3.30.1330.30 6 100 1.3E-19 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS02525 a2f5efa22b484dd92ced39bf31e0adf1 260 Pfam PF00588 SpoU rRNA Methylase family 117 257 3.5E-30 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CNX65_RS02525 a2f5efa22b484dd92ced39bf31e0adf1 260 SUPERFAMILY SSF75217 93 259 2.35E-39 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CNX65_RS16810 8b7092d49d212249d8bc260dbba47282 314 Pfam PF00106 short chain dehydrogenase 15 223 5.1E-22 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16810 8b7092d49d212249d8bc260dbba47282 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 93 104 3.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16810 8b7092d49d212249d8bc260dbba47282 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 181 200 3.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16810 8b7092d49d212249d8bc260dbba47282 314 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 15 32 3.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16810 8b7092d49d212249d8bc260dbba47282 314 SUPERFAMILY SSF51735 11 253 2.26E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16810 8b7092d49d212249d8bc260dbba47282 314 Gene3D G3DSA:3.40.50.720 2 311 6.3E-51 T 28-03-2018 CNX65_RS32040 4e2462fc50475a4d7077bfd05871ad08 235 Pfam PF01636 Phosphotransferase enzyme family 108 164 7.6E-13 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS32040 4e2462fc50475a4d7077bfd05871ad08 235 SUPERFAMILY SSF56112 4 176 3.96E-27 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS32040 4e2462fc50475a4d7077bfd05871ad08 235 Gene3D G3DSA:1.10.510.10 23 182 1.2E-23 T 28-03-2018 CNX65_RS09640 5d843655e07abab82571c4a320185a90 498 SMART SM00813 291 486 6.9E-57 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS09640 5d843655e07abab82571c4a320185a90 498 Gene3D G3DSA:2.60.40.1180 373 494 8.6E-31 T 28-03-2018 CNX65_RS09640 5d843655e07abab82571c4a320185a90 498 SUPERFAMILY SSF51445 18 380 1.86E-103 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09640 5d843655e07abab82571c4a320185a90 498 Pfam PF06964 Alpha-L-arabinofuranosidase C-terminal domain 291 486 1.6E-34 T 28-03-2018 IPR010720 Alpha-L-arabinofuranosidase, C-terminal GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS09640 5d843655e07abab82571c4a320185a90 498 SUPERFAMILY SSF51011 369 493 1.98E-27 T 28-03-2018 CNX65_RS09640 5d843655e07abab82571c4a320185a90 498 Gene3D G3DSA:3.20.20.80 18 372 3.0E-102 T 28-03-2018 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 Gene3D G3DSA:1.20.140.10 220 380 1.3E-53 T 28-03-2018 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 SUPERFAMILY SSF56645 8 243 3.8E-65 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 PIRSF PIRSF016578 209 379 5.4E-10 T 28-03-2018 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 PIRSF PIRSF016578 3 208 1.9E-7 T 28-03-2018 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 126 138 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 6.5E-24 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 217 1.5E-21 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 SUPERFAMILY SSF47203 229 378 3.87E-55 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 Gene3D G3DSA:2.40.110.10 125 219 7.7E-31 T 28-03-2018 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 7.1E-48 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS02665 9f72195ea451594ed749b8f25dfa8f19 381 Gene3D G3DSA:1.10.540.10 5 124 1.1E-26 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS14650 7b48ff91f6944b00cffabdc6bc2b66ab 36 Gene3D G3DSA:1.10.1200.10 1 36 9.4E-8 T 28-03-2018 CNX65_RS14650 7b48ff91f6944b00cffabdc6bc2b66ab 36 SUPERFAMILY SSF47336 1 34 1.83E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS14650 7b48ff91f6944b00cffabdc6bc2b66ab 36 Pfam PF00550 Phosphopantetheine attachment site 1 27 1.4E-4 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS19890 8ab6f6050b1ae10feec398e515422636 501 SUPERFAMILY SSF53850 31 499 4.34E-82 T 28-03-2018 CNX65_RS19890 8ab6f6050b1ae10feec398e515422636 501 PIRSF PIRSF002741 1 496 8.7E-51 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS19890 8ab6f6050b1ae10feec398e515422636 501 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 80 397 1.5E-51 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS19890 8ab6f6050b1ae10feec398e515422636 501 Gene3D G3DSA:3.40.190.10 189 277 2.4E-15 T 28-03-2018 CNX65_RS19890 8ab6f6050b1ae10feec398e515422636 501 Gene3D G3DSA:3.90.76.10 47 188 3.5E-25 T 28-03-2018 CNX65_RS19890 8ab6f6050b1ae10feec398e515422636 501 Gene3D G3DSA:3.10.105.10 278 466 1.4E-25 T 28-03-2018 CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 SUPERFAMILY SSF54637 529 674 1.03E-32 T 28-03-2018 IPR029069 HotDog domain CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 Gene3D G3DSA:3.40.309.10 270 487 6.5E-34 T 28-03-2018 CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 Pfam PF01575 MaoC like domain 546 650 5.4E-20 T 28-03-2018 IPR002539 MaoC-like domain CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 Gene3D G3DSA:3.10.129.10 502 672 2.0E-40 T 28-03-2018 CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 SUPERFAMILY SSF53720 4 503 5.5E-80 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 TIGRFAM TIGR02278 PaaN-DH: phenylacetic acid degradation protein paaN 4 673 0.0 T 28-03-2018 IPR011966 Phenylacetic acid degradation protein PaaN KEGG: 00360+3.3.2.12+1.2.1.91 CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 Pfam PF00171 Aldehyde dehydrogenase family 12 441 1.8E-59 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS26490 6823fb6a5e577c1343858ac53a58b041 675 Gene3D G3DSA:3.40.605.10 2 269 2.4E-41 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS24585 dbe60bf00f9b832de57b7e50b2993f79 350 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 46 317 8.7E-17 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS24585 dbe60bf00f9b832de57b7e50b2993f79 350 Gene3D G3DSA:3.40.50.1110 37 332 5.7E-24 T 28-03-2018 CNX65_RS24585 dbe60bf00f9b832de57b7e50b2993f79 350 SUPERFAMILY SSF52266 41 327 1.18E-40 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS12235 aa652e560adc07456c2a70e50cf555b2 294 SUPERFAMILY SSF161098 51 278 5.89E-58 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12235 aa652e560adc07456c2a70e50cf555b2 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 286 6.0E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12235 aa652e560adc07456c2a70e50cf555b2 294 Gene3D G3DSA:1.10.3720.10 8 291 1.1E-50 T 28-03-2018 CNX65_RS21325 2543d5287b8140a786a77c0934786121 339 SUPERFAMILY SSF56059 121 332 1.06E-34 T 28-03-2018 CNX65_RS21325 2543d5287b8140a786a77c0934786121 339 Pfam PF07478 D-ala D-ala ligase C-terminus 153 330 4.4E-14 T 28-03-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS21325 2543d5287b8140a786a77c0934786121 339 Gene3D G3DSA:3.30.470.20 187 339 4.2E-25 T 28-03-2018 CNX65_RS21325 2543d5287b8140a786a77c0934786121 339 Gene3D G3DSA:3.40.50.20 17 121 5.1E-6 T 28-03-2018 CNX65_RS21325 2543d5287b8140a786a77c0934786121 339 Gene3D G3DSA:3.30.1490.20 122 186 1.3E-11 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS23720 4027b216a6a490a2b7d0bdd7f0632131 414 Gene3D G3DSA:1.20.1250.20 17 208 4.0E-18 T 28-03-2018 CNX65_RS23720 4027b216a6a490a2b7d0bdd7f0632131 414 Gene3D G3DSA:1.20.1250.20 212 406 3.8E-14 T 28-03-2018 CNX65_RS23720 4027b216a6a490a2b7d0bdd7f0632131 414 Pfam PF07690 Major Facilitator Superfamily 27 356 2.1E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS23720 4027b216a6a490a2b7d0bdd7f0632131 414 SUPERFAMILY SSF103473 22 399 2.35E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01055 3b0a32810c2c63f0050f7d3076db258b 188 Pfam PF03358 NADPH-dependent FMN reductase 4 143 5.6E-23 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CNX65_RS01055 3b0a32810c2c63f0050f7d3076db258b 188 SUPERFAMILY SSF52218 4 176 6.1E-32 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS01055 3b0a32810c2c63f0050f7d3076db258b 188 Gene3D G3DSA:3.40.50.360 1 187 7.0E-30 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS33745 bbe34ebc0927b515aa0d675beae02ec0 283 Pfam PF12697 Alpha/beta hydrolase family 64 258 4.4E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS33745 bbe34ebc0927b515aa0d675beae02ec0 283 Gene3D G3DSA:3.40.50.1820 14 278 4.6E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS33745 bbe34ebc0927b515aa0d675beae02ec0 283 SUPERFAMILY SSF53474 35 276 4.77E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22925 5cc6f667e4b200de4f17db268865dd34 283 SUPERFAMILY SSF161098 11 283 4.19E-59 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS22925 5cc6f667e4b200de4f17db268865dd34 283 Gene3D G3DSA:1.10.3720.10 3 270 8.9E-40 T 28-03-2018 CNX65_RS22925 5cc6f667e4b200de4f17db268865dd34 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 274 8.0E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS29210 253017fdf5c737f227a5989e29aa398a 210 Gene3D G3DSA:1.20.120.450 20 155 3.4E-13 T 28-03-2018 CNX65_RS29210 253017fdf5c737f227a5989e29aa398a 210 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 27 149 5.2E-10 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS29210 253017fdf5c737f227a5989e29aa398a 210 SUPERFAMILY SSF109854 24 153 7.02E-12 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS22485 7a6d2404aaf80e42b65cb3a58e870c51 290 Pfam PF00561 alpha/beta hydrolase fold 35 186 4.4E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS22485 7a6d2404aaf80e42b65cb3a58e870c51 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 103 116 2.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS22485 7a6d2404aaf80e42b65cb3a58e870c51 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 59 74 2.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS22485 7a6d2404aaf80e42b65cb3a58e870c51 290 PRINTS PR00111 Alpha/beta hydrolase fold signature 117 130 2.6E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS22485 7a6d2404aaf80e42b65cb3a58e870c51 290 SUPERFAMILY SSF53474 31 288 3.6E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22485 7a6d2404aaf80e42b65cb3a58e870c51 290 Gene3D G3DSA:3.40.50.1820 2 289 1.1E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS06545 83fe8bb4b8e747dce44ce7549df00a2e 79 SUPERFAMILY SSF47336 3 78 1.44E-22 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS06545 83fe8bb4b8e747dce44ce7549df00a2e 79 Gene3D G3DSA:1.10.1200.10 1 79 1.8E-23 T 28-03-2018 CNX65_RS06545 83fe8bb4b8e747dce44ce7549df00a2e 79 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 36 75 5.0E-12 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CNX65_RS06545 83fe8bb4b8e747dce44ce7549df00a2e 79 Pfam PF00550 Phosphopantetheine attachment site 10 75 4.9E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS06545 83fe8bb4b8e747dce44ce7549df00a2e 79 Hamap MF_01217 Acyl carrier protein [acpP]. 5 79 17.223 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CNX65_RS06545 83fe8bb4b8e747dce44ce7549df00a2e 79 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 5 78 7.5E-21 T 28-03-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 CNX65_RS28005 5765f90b5358816e7964f9785a6a2044 210 Gene3D G3DSA:3.40.50.880 1 210 5.2E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS28005 5765f90b5358816e7964f9785a6a2044 210 SUPERFAMILY SSF52317 3 208 2.1E-56 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS28005 5765f90b5358816e7964f9785a6a2044 210 Pfam PF00117 Glutamine amidotransferase class-I 6 206 9.5E-19 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS28005 5765f90b5358816e7964f9785a6a2044 210 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 3 209 31.652 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CNX65_RS28005 5765f90b5358816e7964f9785a6a2044 210 PIRSF PIRSF000495 2 210 4.7E-62 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CNX65_RS28005 5765f90b5358816e7964f9785a6a2044 210 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 4 208 5.2E-61 T 28-03-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 6 29 6.3E-49 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 79 99 6.3E-49 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 161 173 6.3E-49 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 61 73 6.3E-49 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 PRINTS PR00706 Pyroglutamyl peptidase I (C15) family signature 131 147 6.3E-49 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 Pfam PF01470 Pyroglutamyl peptidase 6 199 2.0E-73 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 ProSitePatterns PS01333 Pyrrolidone-carboxylate peptidase glutamic acid active site. 68 84 - T 28-03-2018 IPR033693 Pyroglutamyl peptidase I, Glu active site CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 SUPERFAMILY SSF53182 4 211 4.97E-69 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 ProSitePatterns PS01334 Pyrrolidone-carboxylate peptidase cysteine active site. 129 143 - T 28-03-2018 IPR033694 Pyroglutamyl peptidase I, Cys active site CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 Hamap MF_00417 Pyrrolidone-carboxylate peptidase [pcp]. 4 200 37.568 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 TIGRFAM TIGR00504 pyro_pdase: pyroglutamyl-peptidase I 6 213 1.7E-78 T 28-03-2018 IPR029762 Pyroglutamyl peptidase I, bacterial-type GO:0005829|GO:0006508|GO:0008234|GO:0016920 CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 Gene3D G3DSA:3.40.630.20 1 214 3.2E-64 T 28-03-2018 IPR016125 Peptidase C15, pyroglutamyl peptidase I-like CNX65_RS01725 add7d20d006337b38f81fe4aa0554209 214 PIRSF PIRSF015592 3 212 1.2E-77 T 28-03-2018 IPR000816 Peptidase C15, pyroglutamyl peptidase I GO:0005829|GO:0006508|GO:0016920 CNX65_RS32605 b19b36044aeb6a2f5d1d49d2c04d08f0 203 Pfam PF13828 Domain of unknown function (DUF4190) 23 92 7.3E-9 T 28-03-2018 IPR025241 Domain of unknown function DUF4190 CNX65_RS32605 b19b36044aeb6a2f5d1d49d2c04d08f0 203 Pfam PF05423 Mycobacterium membrane protein 109 200 3.6E-7 T 28-03-2018 IPR008693 Transport accessory protein MmpS CNX65_RS32605 b19b36044aeb6a2f5d1d49d2c04d08f0 203 Gene3D G3DSA:2.60.40.10 92 197 9.9E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Gene3D G3DSA:2.40.40.20 421 563 3.2E-40 T 28-03-2018 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 SMART SM00663 310 589 1.9E-173 T 28-03-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Gene3D G3DSA:2.40.50.100 971 1096 1.0E-35 T 28-03-2018 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Pfam PF04983 RNA polymerase Rpb1, domain 3 564 721 4.6E-23 T 28-03-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 SUPERFAMILY SSF64484 5 1249 0.0 T 28-03-2018 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Pfam PF04997 RNA polymerase Rpb1, domain 1 7 417 1.7E-82 T 28-03-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Pfam PF00623 RNA polymerase Rpb1, domain 2 468 560 2.7E-28 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Pfam PF00623 RNA polymerase Rpb1, domain 2 419 464 2.4E-8 T 28-03-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Pfam PF05000 RNA polymerase Rpb1, domain 4 758 819 1.7E-7 T 28-03-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1258 17.414 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1248 0.0 T 28-03-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32515 6f0be598fc7251bfc091494c9ff49d95 1298 Pfam PF04998 RNA polymerase Rpb1, domain 5 828 1196 1.2E-62 T 28-03-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS19915 f2bf799d6deb21f9455e7da6da113415 399 SUPERFAMILY SSF103473 8 396 1.31E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19915 f2bf799d6deb21f9455e7da6da113415 399 Gene3D G3DSA:1.20.1250.20 216 398 2.9E-15 T 28-03-2018 CNX65_RS19915 f2bf799d6deb21f9455e7da6da113415 399 Gene3D G3DSA:1.20.1250.20 11 204 4.2E-17 T 28-03-2018 CNX65_RS19915 f2bf799d6deb21f9455e7da6da113415 399 Pfam PF07690 Major Facilitator Superfamily 21 276 8.8E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 Gene3D G3DSA:1.25.10.10 21 184 1.7E-12 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 Gene3D G3DSA:1.25.40.70 185 311 0.0052 T 28-03-2018 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 Gene3D G3DSA:1.25.40.70 312 375 6.7E-4 T 28-03-2018 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 Gene3D G3DSA:1.25.40.70 464 617 0.037 T 28-03-2018 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 SMART SM00567 E-Z type HEAT repeats 301 332 37.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 SMART SM00567 E-Z type HEAT repeats 347 371 140.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 SMART SM00567 E-Z type HEAT repeats 522 553 890.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 SMART SM00567 E-Z type HEAT repeats 123 152 330.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 SUPERFAMILY SSF48371 288 369 1.89E-18 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS19945 600af59c3e2766efae5f5cee95e61ba3 617 SUPERFAMILY SSF48371 26 207 1.89E-18 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 Gene3D G3DSA:3.40.50.300 175 353 6.1E-11 T 28-03-2018 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 Gene3D G3DSA:1.25.40.10 986 1220 2.8E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 Gene3D G3DSA:1.10.10.10 1221 1266 1.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 SUPERFAMILY SSF46894 1201 1262 1.53E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 SMART SM00028 701 734 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 SMART SM00028 1149 1182 0.19 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 SMART SM00421 1207 1264 5.5E-19 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 Pfam PF13191 AAA ATPase domain 174 312 6.2E-14 T 28-03-2018 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 Pfam PF00196 Bacterial regulatory proteins, luxR family 1210 1260 4.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 Gene3D G3DSA:1.25.40.10 701 883 0.008 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1240 1252 4.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1210 1224 4.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 1224 1240 4.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS05870 f4c8b0fd447cd10e5cb962e73e5b8d42 1272 SUPERFAMILY SSF52540 173 391 3.72E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22875 e643a9b8a59d3ac39b5009a0444074f6 405 Gene3D G3DSA:3.40.50.20 1 117 3.2E-7 T 28-03-2018 CNX65_RS22875 e643a9b8a59d3ac39b5009a0444074f6 405 Gene3D G3DSA:3.30.1490.20 118 179 7.7E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS22875 e643a9b8a59d3ac39b5009a0444074f6 405 Pfam PF13535 ATP-grasp domain 144 277 1.6E-14 T 28-03-2018 CNX65_RS22875 e643a9b8a59d3ac39b5009a0444074f6 405 Gene3D G3DSA:3.30.470.20 180 391 3.1E-16 T 28-03-2018 CNX65_RS22875 e643a9b8a59d3ac39b5009a0444074f6 405 SUPERFAMILY SSF56059 101 320 3.54E-31 T 28-03-2018 CNX65_RS30155 66c561b2d4821773a9799d92f99ecf94 176 Pfam PF00857 Isochorismatase family 3 143 3.3E-27 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS30155 66c561b2d4821773a9799d92f99ecf94 176 SUPERFAMILY SSF52499 2 175 2.35E-39 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS30155 66c561b2d4821773a9799d92f99ecf94 176 Gene3D G3DSA:3.40.50.850 1 176 7.3E-43 T 28-03-2018 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 11 383 4.5E-139 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 Gene3D G3DSA:3.90.1150.10 1 170 5.4E-50 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 Gene3D G3DSA:3.40.640.10 171 282 3.8E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 213 250 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 Pfam PF00202 Aminotransferase class-III 17 381 2.3E-109 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 PIRSF PIRSF000521 162 387 3.0E-30 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 PIRSF PIRSF000521 5 123 3.0E-10 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 PIRSF PIRSF000521 116 148 0.65 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 Gene3D G3DSA:3.90.1150.10 283 387 8.2E-23 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 8 386 43.378 T 28-03-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 CNX65_RS27170 a355b92f6aee21befe7a481bd1931d95 387 SUPERFAMILY SSF53383 10 385 9.14E-126 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS01600 54a98e67ecf17b5bebea0157b4c9ae24 182 SUPERFAMILY SSF53271 3 180 3.54E-54 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS01600 54a98e67ecf17b5bebea0157b4c9ae24 182 Gene3D G3DSA:3.40.50.2020 1 182 2.9E-43 T 28-03-2018 CNX65_RS01600 54a98e67ecf17b5bebea0157b4c9ae24 182 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 9 175 2.2E-67 T 28-03-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 CNX65_RS01600 54a98e67ecf17b5bebea0157b4c9ae24 182 Pfam PF00156 Phosphoribosyl transferase domain 10 162 2.9E-24 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CNX65_RS30265 da54a9305bb5f36c4f1831c23b79e9ec 707 Gene3D G3DSA:2.130.10.10 1 378 6.9E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS30265 da54a9305bb5f36c4f1831c23b79e9ec 707 Pfam PF04775 Acyl-CoA thioester hydrolase/BAAT N-terminal region 75 145 3.3E-20 T 28-03-2018 IPR006862 Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase CNX65_RS30265 da54a9305bb5f36c4f1831c23b79e9ec 707 Pfam PF08840 BAAT / Acyl-CoA thioester hydrolase C terminal 478 702 1.5E-34 T 28-03-2018 IPR014940 BAAT/Acyl-CoA thioester hydrolase C-terminal CNX65_RS30265 da54a9305bb5f36c4f1831c23b79e9ec 707 SUPERFAMILY SSF53474 566 659 8.18E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30265 da54a9305bb5f36c4f1831c23b79e9ec 707 SUPERFAMILY SSF53474 417 530 8.18E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30265 da54a9305bb5f36c4f1831c23b79e9ec 707 SUPERFAMILY SSF53474 687 705 8.18E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30265 da54a9305bb5f36c4f1831c23b79e9ec 707 Gene3D G3DSA:3.40.50.1820 416 704 8.9E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27480 ad4168023588ca18e1ec2e7eff0c21ba 181 Gene3D G3DSA:2.40.380.10 5 175 7.5E-51 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS27480 ad4168023588ca18e1ec2e7eff0c21ba 181 SUPERFAMILY SSF159234 15 179 2.48E-46 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS27480 ad4168023588ca18e1ec2e7eff0c21ba 181 Pfam PF04167 Protein of unknown function (DUF402) 65 130 1.3E-13 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS02800 ce2c8cfe1f97d768dc4c08ae87cdf901 275 PIRSF PIRSF016184 1 274 1.0E-60 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CNX65_RS02800 ce2c8cfe1f97d768dc4c08ae87cdf901 275 Gene3D G3DSA:3.10.310.10 2 117 6.1E-28 T 28-03-2018 CNX65_RS02800 ce2c8cfe1f97d768dc4c08ae87cdf901 275 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 2 272 1.9E-46 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CNX65_RS02800 ce2c8cfe1f97d768dc4c08ae87cdf901 275 Gene3D G3DSA:3.10.310.10 118 265 9.6E-35 T 28-03-2018 CNX65_RS02800 ce2c8cfe1f97d768dc4c08ae87cdf901 275 Pfam PF02567 Phenazine biosynthesis-like protein 7 272 6.3E-63 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CNX65_RS02800 ce2c8cfe1f97d768dc4c08ae87cdf901 275 SUPERFAMILY SSF54506 4 270 9.07E-58 T 28-03-2018 CNX65_RS00605 ec8c2ba6ee3bac6e5dc3241a2b008595 392 Pfam PF01266 FAD dependent oxidoreductase 3 388 2.8E-65 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS00605 ec8c2ba6ee3bac6e5dc3241a2b008595 392 Gene3D G3DSA:3.40.50.20 2 95 7.1E-8 T 28-03-2018 CNX65_RS00605 ec8c2ba6ee3bac6e5dc3241a2b008595 392 SUPERFAMILY SSF51905 3 281 5.18E-50 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS00605 ec8c2ba6ee3bac6e5dc3241a2b008595 392 Gene3D G3DSA:3.30.9.10 96 157 7.3E-11 T 28-03-2018 CNX65_RS00605 ec8c2ba6ee3bac6e5dc3241a2b008595 392 Gene3D G3DSA:3.30.9.10 158 346 2.1E-31 T 28-03-2018 CNX65_RS08190 09c5617df95b9b7b9d9656f96af70f53 527 Gene3D G3DSA:3.40.50.300 3 310 1.2E-26 T 28-03-2018 CNX65_RS08190 09c5617df95b9b7b9d9656f96af70f53 527 SUPERFAMILY SSF52540 3 219 3.72E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08190 09c5617df95b9b7b9d9656f96af70f53 527 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 48 1.1E-6 T 28-03-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain CNX65_RS10975 3dbca1bde38a0864115ce1eb8eff7ceb 217 Pfam PF00486 Transcriptional regulatory protein, C terminal 144 215 7.8E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS10975 3dbca1bde38a0864115ce1eb8eff7ceb 217 Gene3D G3DSA:3.40.50.2300 1 119 4.6E-30 T 28-03-2018 CNX65_RS10975 3dbca1bde38a0864115ce1eb8eff7ceb 217 SMART SM00862 143 215 1.0E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS10975 3dbca1bde38a0864115ce1eb8eff7ceb 217 Gene3D G3DSA:1.10.10.10 120 216 1.4E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10975 3dbca1bde38a0864115ce1eb8eff7ceb 217 Pfam PF00072 Response regulator receiver domain 3 109 1.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS10975 3dbca1bde38a0864115ce1eb8eff7ceb 217 SUPERFAMILY SSF52172 2 181 2.7E-34 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS10975 3dbca1bde38a0864115ce1eb8eff7ceb 217 SMART SM00448 1 109 1.5E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS27985 358ed9ca492e4d6089a2c06b622ad3a9 129 Pfam PF02661 Fic/DOC family 8 86 7.0E-8 T 28-03-2018 IPR003812 Fido domain CNX65_RS27985 358ed9ca492e4d6089a2c06b622ad3a9 129 Gene3D G3DSA:1.10.3290.10 4 116 1.6E-5 T 28-03-2018 IPR003812 Fido domain CNX65_RS05530 d8ff096a797a8aa83d8974b4c9f948e6 169 Pfam PF00293 NUDIX domain 16 128 1.6E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS05530 d8ff096a797a8aa83d8974b4c9f948e6 169 SUPERFAMILY SSF55811 15 134 7.45E-24 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS05530 d8ff096a797a8aa83d8974b4c9f948e6 169 PRINTS PR00502 NUDIX hydrolase family signature 42 56 2.9E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS05530 d8ff096a797a8aa83d8974b4c9f948e6 169 PRINTS PR00502 NUDIX hydrolase family signature 56 71 2.9E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS05530 d8ff096a797a8aa83d8974b4c9f948e6 169 Gene3D G3DSA:3.90.79.10 6 158 5.0E-24 T 28-03-2018 CNX65_RS05530 d8ff096a797a8aa83d8974b4c9f948e6 169 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 Pfam PF10502 Signal peptidase, peptidase S26 131 227 1.4E-5 T 28-03-2018 IPR019533 Peptidase S26 CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 ProSitePatterns PS00761 Signal peptidases I signature 3. 189 202 - T 28-03-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 31 229 1.2E-35 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 Pfam PF00717 Peptidase S24-like 51 97 1.7E-5 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 SUPERFAMILY SSF51306 43 95 2.41E-41 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 SUPERFAMILY SSF51306 127 236 2.41E-41 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 132 144 1.7E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 184 203 1.7E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 44 60 1.7E-19 T 28-03-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 CNX65_RS29055 2d9e7fe42f919f44d00a4d7f9d46b45c 288 Gene3D G3DSA:2.10.109.10 40 246 5.0E-42 T 28-03-2018 CNX65_RS34010 7c83a62b06d0b421693a1c9438a8958a 207 SMART SM00849 7 172 1.8E-7 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS34010 7c83a62b06d0b421693a1c9438a8958a 207 Pfam PF13483 Beta-lactamase superfamily domain 2 172 2.5E-21 T 28-03-2018 CNX65_RS34010 7c83a62b06d0b421693a1c9438a8958a 207 SUPERFAMILY SSF56281 2 178 7.73E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS34010 7c83a62b06d0b421693a1c9438a8958a 207 Gene3D G3DSA:3.60.15.10 1 207 3.3E-25 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 Gene3D G3DSA:3.40.50.980 180 336 4.1E-37 T 28-03-2018 CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 SUPERFAMILY SSF56801 30 530 6.41E-125 T 28-03-2018 CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 Pfam PF00501 AMP-binding enzyme 38 432 1.5E-87 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 Gene3D G3DSA:3.30.300.30 427 532 2.4E-17 T 28-03-2018 CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 58 457 3.6E-104 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 Gene3D G3DSA:2.30.38.10 346 422 1.1E-23 T 28-03-2018 CNX65_RS21090 c3706def13a75122190ff02bf1c5ce58 552 Gene3D G3DSA:3.40.50.980 31 179 7.9E-39 T 28-03-2018 CNX65_RS23410 de93b3eabb264a911a30422852f2c8ef 283 Pfam PF13460 NAD(P)H-binding 12 177 4.3E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23410 de93b3eabb264a911a30422852f2c8ef 283 Gene3D G3DSA:3.40.50.720 2 105 2.0E-6 T 28-03-2018 CNX65_RS23410 de93b3eabb264a911a30422852f2c8ef 283 SUPERFAMILY SSF51735 3 270 3.73E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23410 de93b3eabb264a911a30422852f2c8ef 283 Gene3D G3DSA:3.40.50.720 110 260 9.8E-16 T 28-03-2018 CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 Pfam PF03466 LysR substrate binding domain 88 279 1.6E-37 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 3.0E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 3.0E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 3.0E-10 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 SUPERFAMILY SSF46785 1 84 2.4E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 SUPERFAMILY SSF53850 89 279 2.74E-37 T 28-03-2018 CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 Gene3D G3DSA:3.40.190.10 176 256 8.1E-16 T 28-03-2018 CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 Gene3D G3DSA:3.40.190.10 87 175 2.4E-22 T 28-03-2018 CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 Gene3D G3DSA:1.10.10.10 1 83 4.3E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15485 c65bbdf9d9be4ea44cce7145b1a932bd 285 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 6.7E-23 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS05295 0975f1cb4f6345c20664bc3eed540b3a 400 Pfam PF03734 L,D-transpeptidase catalytic domain 259 370 8.5E-16 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CNX65_RS05295 0975f1cb4f6345c20664bc3eed540b3a 400 Gene3D G3DSA:2.40.440.10 240 372 5.4E-26 T 28-03-2018 CNX65_RS05295 0975f1cb4f6345c20664bc3eed540b3a 400 SUPERFAMILY SSF141523 251 370 4.58E-28 T 28-03-2018 CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 Pfam PF00561 alpha/beta hydrolase fold 29 282 8.0E-24 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 TIGRFAM TIGR01250 pro_imino_pep_2: proline-specific peptidase 8 293 2.5E-73 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 Gene3D G3DSA:3.40.50.1820 5 296 3.6E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 SUPERFAMILY SSF53474 9 294 1.74E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 58 69 1.3E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 31 39 1.3E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 PRINTS PR00793 Prolyl aminopeptidase (S33) family signature 104 118 1.3E-10 T 28-03-2018 IPR002410 Peptidase S33 GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS13595 77ea285aa76194d1909e4f9ba0649c08 296 PIRSF PIRSF005539 1 296 4.1E-110 T 28-03-2018 IPR005945 Proline-specific peptidase GO:0006508|GO:0008233 KEGG: 00330+3.4.11.5 CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 SMART SM00344 1 105 2.8E-34 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 SUPERFAMILY SSF46785 1 57 1.26E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 ProSitePatterns PS00519 AsnC-type HTH domain signature. 16 42 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 SUPERFAMILY SSF54909 58 140 1.11E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 Pfam PF01037 Lrp/AsnC ligand binding domain 64 135 6.7E-17 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 25 44 3.0E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 14 25 3.0E-8 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 Pfam PF13404 AsnC-type helix-turn-helix domain 1 39 5.0E-16 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 Gene3D G3DSA:3.30.70.920 51 143 7.0E-21 T 28-03-2018 CNX65_RS33055 fecb7e218de0e414a5df20eb3de41bc4 150 Gene3D G3DSA:1.10.10.10 1 50 2.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19600 c3531fd9d7ff8e2fc61d57758165df2e 334 Pfam PF09924 Uncharacterised conserved protein (DUF2156) 19 315 1.3E-64 T 28-03-2018 IPR024320 Phosphatidylglycerol lysyltransferase, C-terminal CNX65_RS19600 c3531fd9d7ff8e2fc61d57758165df2e 334 SUPERFAMILY SSF55729 131 264 2.12E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS19600 c3531fd9d7ff8e2fc61d57758165df2e 334 SUPERFAMILY SSF55729 295 321 2.12E-13 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS19600 c3531fd9d7ff8e2fc61d57758165df2e 334 Gene3D G3DSA:3.40.630.30 123 303 6.9E-9 T 28-03-2018 CNX65_RS03115 29d1b80274d155b64a84c4c0b0497c13 293 Gene3D G3DSA:3.90.550.10 2 292 6.4E-50 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS03115 29d1b80274d155b64a84c4c0b0497c13 293 Pfam PF00483 Nucleotidyl transferase 7 269 5.9E-28 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CNX65_RS03115 29d1b80274d155b64a84c4c0b0497c13 293 SUPERFAMILY SSF53448 6 282 7.89E-56 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 Pfam PF02887 Pyruvate kinase, alpha/beta domain 355 466 9.4E-25 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 SUPERFAMILY SSF52935 322 468 4.97E-36 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 Gene3D G3DSA:3.20.20.60 160 320 9.3E-61 T 28-03-2018 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 SUPERFAMILY SSF51621 2 76 4.19E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 SUPERFAMILY SSF51621 166 337 4.19E-94 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 SUPERFAMILY SSF50800 71 165 1.33E-26 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 PRINTS PR01050 Pyruvate kinase family signature 243 267 3.0E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 PRINTS PR01050 Pyruvate kinase family signature 268 292 3.0E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 PRINTS PR01050 Pyruvate kinase family signature 216 242 3.0E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 PRINTS PR01050 Pyruvate kinase family signature 312 328 3.0E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 PRINTS PR01050 Pyruvate kinase family signature 185 199 3.0E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 PRINTS PR01050 Pyruvate kinase family signature 293 311 3.0E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 PRINTS PR01050 Pyruvate kinase family signature 60 76 3.0E-64 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 Pfam PF00224 Pyruvate kinase, barrel domain 3 337 2.0E-119 T 28-03-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 ProSitePatterns PS00110 Pyruvate kinase active site signature. 214 226 - T 28-03-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 3 467 3.9E-169 T 28-03-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 Gene3D G3DSA:2.40.33.10 76 159 7.6E-29 T 28-03-2018 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 Gene3D G3DSA:3.20.20.60 1 75 1.0E-16 T 28-03-2018 CNX65_RS27870 5695965cc9aeba5cda50469a3e6e2940 474 Gene3D G3DSA:3.40.1380.20 321 469 1.8E-40 T 28-03-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 CNX65_RS33180 53cf6b11684de752685983f29265e032 583 Gene3D G3DSA:2.60.40.650 478 583 1.8E-21 T 28-03-2018 CNX65_RS33180 53cf6b11684de752685983f29265e032 583 Gene3D G3DSA:3.90.420.10 280 477 5.3E-51 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CNX65_RS33180 53cf6b11684de752685983f29265e032 583 SUPERFAMILY SSF56524 293 478 4.32E-54 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CNX65_RS33180 53cf6b11684de752685983f29265e032 583 SUPERFAMILY SSF81296 475 582 8.4E-20 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS33180 53cf6b11684de752685983f29265e032 583 Pfam PF00174 Oxidoreductase molybdopterin binding domain 310 457 2.3E-36 T 28-03-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 CNX65_RS04880 4fd0f30c96398a50bdd6b62c7073dc3e 315 SUPERFAMILY SSF161098 69 297 3.27E-51 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS04880 4fd0f30c96398a50bdd6b62c7073dc3e 315 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 305 1.5E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS04880 4fd0f30c96398a50bdd6b62c7073dc3e 315 Gene3D G3DSA:1.10.3720.10 27 310 3.8E-49 T 28-03-2018 CNX65_RS04880 4fd0f30c96398a50bdd6b62c7073dc3e 315 SUPERFAMILY SSF160964 26 59 7.19E-5 T 28-03-2018 CNX65_RS11515 eb140edcaacda14cbac7e4f289c6d4a0 408 Pfam PF00990 Diguanylate cyclase, GGDEF domain 233 390 6.4E-40 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS11515 eb140edcaacda14cbac7e4f289c6d4a0 408 SMART SM00267 222 394 3.5E-48 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS11515 eb140edcaacda14cbac7e4f289c6d4a0 408 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 229 392 3.4E-44 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS11515 eb140edcaacda14cbac7e4f289c6d4a0 408 Gene3D G3DSA:3.30.70.270 217 394 7.5E-50 T 28-03-2018 CNX65_RS11515 eb140edcaacda14cbac7e4f289c6d4a0 408 SUPERFAMILY SSF55073 239 391 2.59E-41 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS30575 bf90d1c591209f97ff7ec715faff08e1 391 SUPERFAMILY SSF50182 174 239 1.37E-12 T 28-03-2018 IPR010920 LSM domain CNX65_RS30575 bf90d1c591209f97ff7ec715faff08e1 391 Pfam PF00924 Mechanosensitive ion channel 136 278 4.0E-25 T 28-03-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 CNX65_RS30575 bf90d1c591209f97ff7ec715faff08e1 391 Gene3D G3DSA:2.30.30.60 190 240 3.8E-9 T 28-03-2018 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 SUPERFAMILY SSF54373 326 456 9.12E-20 T 28-03-2018 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 Gene3D G3DSA:3.30.560.10 104 471 1.0E-79 T 28-03-2018 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 ProSitePatterns PS00624 GMC oxidoreductases signature 2. 256 270 - T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 Pfam PF00732 GMC oxidoreductase 6 296 1.5E-62 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 Pfam PF05199 GMC oxidoreductase 369 508 2.5E-35 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 Gene3D G3DSA:4.10.450.10 45 103 1.8E-13 T 28-03-2018 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 PIRSF PIRSF000137 1 326 8.7E-65 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 PIRSF PIRSF000137 310 514 4.9E-39 T 28-03-2018 IPR012132 Glucose-methanol-choline oxidoreductase GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 SUPERFAMILY SSF51905 455 513 2.88E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20530 fa91f8087a63274c6a451f12b6dc5e71 515 SUPERFAMILY SSF51905 1 290 2.88E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24745 9116d88b9028205ff6655264bd3db29d 468 Gene3D G3DSA:2.60.120.10 86 227 1.5E-18 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS24745 9116d88b9028205ff6655264bd3db29d 468 SUPERFAMILY SSF51206 85 212 7.73E-20 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS24745 9116d88b9028205ff6655264bd3db29d 468 Pfam PF00027 Cyclic nucleotide-binding domain 113 197 2.4E-11 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS24745 9116d88b9028205ff6655264bd3db29d 468 SMART SM00100 93 219 1.9E-4 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS18250 9ee3c3bc39d4b731cece7a06a972046f 395 Gene3D G3DSA:3.30.450.20 12 138 9.5E-7 T 28-03-2018 CNX65_RS18250 9ee3c3bc39d4b731cece7a06a972046f 395 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 209 393 1.7E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18250 9ee3c3bc39d4b731cece7a06a972046f 395 SMART SM00331 185 393 4.1E-24 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18250 9ee3c3bc39d4b731cece7a06a972046f 395 Gene3D G3DSA:3.60.40.10 139 394 2.3E-27 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS18250 9ee3c3bc39d4b731cece7a06a972046f 395 SUPERFAMILY SSF81606 194 391 6.28E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 Pfam PF03466 LysR substrate binding domain 88 282 3.6E-39 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 SUPERFAMILY SSF46785 2 112 8.82E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 62 2.4E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 Gene3D G3DSA:1.10.10.10 1 82 4.2E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 SUPERFAMILY SSF53850 88 282 1.49E-35 T 28-03-2018 CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 Gene3D G3DSA:3.40.190.10 92 174 2.9E-25 T 28-03-2018 CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 Gene3D G3DSA:3.40.190.10 175 259 6.1E-20 T 28-03-2018 CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 1.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 1.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15680 2380a0c74c1bfe8e97f6dfdf4db999a8 283 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 1.8E-5 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS33280 fad9b81bbf298f75e6857569d52bb08b 211 Gene3D G3DSA:1.10.10.10 82 210 1.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33280 fad9b81bbf298f75e6857569d52bb08b 211 SUPERFAMILY SSF46894 158 211 1.73E-6 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 Gene3D G3DSA:3.40.50.720 2 280 6.3E-56 T 28-03-2018 CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 2.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 2.5E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 Pfam PF00106 short chain dehydrogenase 6 185 1.1E-43 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 9.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 9.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 9.7E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24885 a28b8ae20c4c605f2fab84e140a91870 281 SUPERFAMILY SSF51735 3 249 5.24E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 287 333 9.0E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 SUPERFAMILY SSF55781 25 167 1.79E-17 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 Gene3D G3DSA:3.30.565.10 204 372 1.6E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 Gene3D G3DSA:3.30.450.40 6 179 7.3E-23 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 SUPERFAMILY SSF55874 248 371 5.5E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 Pfam PF07730 Histidine kinase 176 239 3.2E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 SMART SM00065 25 169 5.2E-5 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 SMART SM00387 283 372 6.9E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS00485 32d9425bf1fae939c9ca5eb66b43c66e 372 Pfam PF13185 GAF domain 25 159 7.0E-15 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS28960 c721500662fff9b49c8c0384e0cc7ac6 368 SUPERFAMILY SSF102114 112 339 1.15E-17 T 28-03-2018 CNX65_RS28960 c721500662fff9b49c8c0384e0cc7ac6 368 SMART SM00729 117 342 0.0024 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS28960 c721500662fff9b49c8c0384e0cc7ac6 368 Gene3D G3DSA:3.20.20.70 26 364 3.0E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS28960 c721500662fff9b49c8c0384e0cc7ac6 368 PIRSF PIRSF006004 12 368 4.0E-118 T 28-03-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28960 c721500662fff9b49c8c0384e0cc7ac6 368 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 20 366 4.3E-97 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28960 c721500662fff9b49c8c0384e0cc7ac6 368 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 17 368 65.762 T 28-03-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS28960 c721500662fff9b49c8c0384e0cc7ac6 368 Pfam PF04055 Radical SAM superfamily 122 294 1.3E-20 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS16215 6c87760b3cd0e6b876bfb49803d25b48 465 TIGRFAM TIGR01686 FkbH: FkbH domain 6 314 3.2E-94 T 28-03-2018 IPR010037 FkbH domain CNX65_RS16215 6c87760b3cd0e6b876bfb49803d25b48 465 SUPERFAMILY SSF56784 6 109 1.12E-10 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS16215 6c87760b3cd0e6b876bfb49803d25b48 465 Gene3D G3DSA:3.40.50.1000 5 112 7.4E-12 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS16215 6c87760b3cd0e6b876bfb49803d25b48 465 Gene3D G3DSA:3.40.630.30 178 315 3.1E-9 T 28-03-2018 CNX65_RS16215 6c87760b3cd0e6b876bfb49803d25b48 465 TIGRFAM TIGR01681 HAD-SF-IIIC: HAD phosphatase, family IIIC 7 116 1.4E-12 T 28-03-2018 IPR010033 HAD-superfamily phosphatase, subfamily IIIC CNX65_RS16215 6c87760b3cd0e6b876bfb49803d25b48 465 SUPERFAMILY SSF55729 182 290 1.53E-6 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 323 341 3.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 404 426 3.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 182 191 3.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 96 113 3.4E-24 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 SUPERFAMILY SSF50621 283 436 3.14E-47 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 296 394 4.3E-17 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 58 305 3.7E-59 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 29 437 5.8E-123 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 Gene3D G3DSA:2.40.37.10 295 437 2.2E-40 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 38 437 39.215 T 28-03-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 SUPERFAMILY SSF51419 49 307 2.04E-71 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 295 314 1.8E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 98 110 1.8E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 210 223 1.8E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 78 96 1.8E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 394 407 1.8E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS16490 7c9aebfe62a80db302e6114a4ba186aa 437 Gene3D G3DSA:3.20.20.10 57 294 1.9E-64 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 SUPERFAMILY SSF117074 157 230 2.22E-11 T 28-03-2018 CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 SUPERFAMILY SSF117074 352 429 9.94E-12 T 28-03-2018 CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 SUPERFAMILY SSF117074 61 112 8.37E-12 T 28-03-2018 CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Pfam PF17210 SdrD B-like domain 365 426 4.9E-11 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Pfam PF17210 SdrD B-like domain 162 228 1.2E-8 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Pfam PF17210 SdrD B-like domain 61 127 6.0E-11 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Pfam PF17210 SdrD B-like domain 267 341 5.8E-11 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 SUPERFAMILY SSF117074 267 339 5.62E-13 T 28-03-2018 CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Gene3D G3DSA:2.60.40.10 360 459 1.6E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Gene3D G3DSA:2.60.40.10 38 149 9.7E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Gene3D G3DSA:2.60.40.10 157 248 1.1E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS13685 1f30f89bd23e20e550608448a881e4a9 542 Gene3D G3DSA:2.60.40.10 264 355 2.9E-15 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 Pfam PF00931 NB-ARC domain 113 348 2.4E-12 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 PRINTS PR00364 Disease resistance protein signature 275 289 9.6E-9 T 28-03-2018 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 PRINTS PR00364 Disease resistance protein signature 190 204 9.6E-9 T 28-03-2018 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 PRINTS PR00364 Disease resistance protein signature 116 131 9.6E-9 T 28-03-2018 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 Gene3D G3DSA:1.25.40.10 616 765 1.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 SMART SM00382 113 258 0.0045 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 SUPERFAMILY SSF52540 85 342 1.74E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 SUPERFAMILY SSF48452 534 717 5.9E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 Pfam PF13560 Helix-turn-helix domain 5 67 9.0E-17 T 28-03-2018 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 Gene3D G3DSA:1.10.260.40 2 77 1.9E-16 T 28-03-2018 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 Gene3D G3DSA:1.25.40.10 436 615 0.095 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 SUPERFAMILY SSF47413 3 61 1.53E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 Gene3D G3DSA:3.40.50.300 78 228 1.6E-18 T 28-03-2018 CNX65_RS27275 c62453b0f86888cce5e3dff305242db1 765 SMART SM00530 8 64 3.3E-14 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS18815 c01f89425a66680ab804a12515674cd8 280 SUPERFAMILY SSF53474 75 251 1.01E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18815 c01f89425a66680ab804a12515674cd8 280 Pfam PF12695 Alpha/beta hydrolase family 109 266 3.1E-37 T 28-03-2018 IPR029059 Alpha/beta hydrolase fold-5 CNX65_RS18815 c01f89425a66680ab804a12515674cd8 280 Gene3D G3DSA:3.40.50.1820 88 256 1.4E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20010 37386b2bb4739660de90875cc6a25107 380 Pfam PF13676 TIR domain 4 124 9.3E-9 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS20010 37386b2bb4739660de90875cc6a25107 380 SUPERFAMILY SSF52200 3 68 3.53E-6 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS20010 37386b2bb4739660de90875cc6a25107 380 Gene3D G3DSA:3.40.50.10140 1 148 7.6E-9 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS28740 00ad938f20ddcd00a279d7510f8beb02 376 SUPERFAMILY SSF53790 1 231 1.57E-50 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28740 00ad938f20ddcd00a279d7510f8beb02 376 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 205 1.6E-37 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28740 00ad938f20ddcd00a279d7510f8beb02 376 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS28740 00ad938f20ddcd00a279d7510f8beb02 376 Gene3D G3DSA:3.30.950.10 125 234 9.2E-18 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28740 00ad938f20ddcd00a279d7510f8beb02 376 Gene3D G3DSA:3.40.1010.10 2 124 3.1E-29 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS21590 41912f7c70fc1accb6dbb3550180a0e2 404 SUPERFAMILY SSF51679 31 376 8.9E-74 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS21590 41912f7c70fc1accb6dbb3550180a0e2 404 Pfam PF00296 Luciferase-like monooxygenase 39 344 4.0E-69 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS21590 41912f7c70fc1accb6dbb3550180a0e2 404 Gene3D G3DSA:3.20.20.30 21 403 4.6E-73 T 28-03-2018 CNX65_RS23025 40a481aee962d1314a46fd33130be0a2 283 SUPERFAMILY SSF51735 9 151 1.17E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23025 40a481aee962d1314a46fd33130be0a2 283 Gene3D G3DSA:1.10.1040.10 168 283 1.0E-7 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS23025 40a481aee962d1314a46fd33130be0a2 283 Gene3D G3DSA:3.40.50.720 5 167 1.0E-19 T 28-03-2018 CNX65_RS23025 40a481aee962d1314a46fd33130be0a2 283 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 9 151 2.6E-12 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS23025 40a481aee962d1314a46fd33130be0a2 283 PIRSF PIRSF000103 3 282 1.1E-27 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CNX65_RS22295 cd23dcf8be1e1ed62cc13dfa88781b53 320 SUPERFAMILY SSF55347 122 285 3.6E-31 T 28-03-2018 CNX65_RS22295 cd23dcf8be1e1ed62cc13dfa88781b53 320 Gene3D G3DSA:3.40.50.720 1 136 6.1E-41 T 28-03-2018 CNX65_RS22295 cd23dcf8be1e1ed62cc13dfa88781b53 320 SUPERFAMILY SSF51735 1 147 1.89E-42 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22295 cd23dcf8be1e1ed62cc13dfa88781b53 320 Gene3D G3DSA:3.30.360.10 137 319 9.8E-32 T 28-03-2018 CNX65_RS22295 cd23dcf8be1e1ed62cc13dfa88781b53 320 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 113 7.5E-22 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS22760 98522406a368751d976226abbdbe76a1 352 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 236 7.4E-36 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS22760 98522406a368751d976226abbdbe76a1 352 Gene3D G3DSA:3.40.50.720 1 307 2.7E-41 T 28-03-2018 CNX65_RS22760 98522406a368751d976226abbdbe76a1 352 SUPERFAMILY SSF51735 1 299 4.48E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24750 a87a5da8015914dd07e683b6e663d9ef 469 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 124 140 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CNX65_RS24750 a87a5da8015914dd07e683b6e663d9ef 469 Gene3D G3DSA:2.60.120.10 78 229 4.0E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS24750 a87a5da8015914dd07e683b6e663d9ef 469 Pfam PF00027 Cyclic nucleotide-binding domain 116 203 1.6E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS24750 a87a5da8015914dd07e683b6e663d9ef 469 SUPERFAMILY SSF51206 86 207 2.88E-21 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS24750 a87a5da8015914dd07e683b6e663d9ef 469 SMART SM00100 96 219 1.6E-6 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS15020 bdd768ea9e688694b9fb0731a99f4131 425 Gene3D G3DSA:3.40.190.10 225 376 4.5E-9 T 28-03-2018 CNX65_RS15020 bdd768ea9e688694b9fb0731a99f4131 425 Gene3D G3DSA:3.40.190.10 16 198 8.9E-30 T 28-03-2018 CNX65_RS15020 bdd768ea9e688694b9fb0731a99f4131 425 SUPERFAMILY SSF53850 18 420 9.32E-69 T 28-03-2018 CNX65_RS15020 bdd768ea9e688694b9fb0731a99f4131 425 Pfam PF13416 Bacterial extracellular solute-binding protein 49 340 1.2E-29 T 28-03-2018 CNX65_RS01595 940de237463aa8fb3a05204931660991 308 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 27 196 1.1E-35 T 28-03-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CNX65_RS01595 940de237463aa8fb3a05204931660991 308 SUPERFAMILY SSF52402 25 227 9.43E-45 T 28-03-2018 CNX65_RS01595 940de237463aa8fb3a05204931660991 308 Pfam PF01171 PP-loop family 28 192 4.1E-31 T 28-03-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 CNX65_RS01595 940de237463aa8fb3a05204931660991 308 Pfam PF09179 TilS substrate binding domain 238 301 1.0E-13 T 28-03-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CNX65_RS01595 940de237463aa8fb3a05204931660991 308 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 16 295 19.729 T 28-03-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 CNX65_RS01595 940de237463aa8fb3a05204931660991 308 SUPERFAMILY SSF82829 205 300 3.14E-12 T 28-03-2018 CNX65_RS01595 940de237463aa8fb3a05204931660991 308 Gene3D G3DSA:3.40.50.620 24 226 5.5E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS25310 fa2e95348f29b8cbdae5b72bc45ee06d 132 SUPERFAMILY SSF55874 31 128 6.29E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25310 fa2e95348f29b8cbdae5b72bc45ee06d 132 Gene3D G3DSA:3.30.565.10 4 132 2.5E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS25310 fa2e95348f29b8cbdae5b72bc45ee06d 132 Pfam PF13581 Histidine kinase-like ATPase domain 14 123 2.8E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 Pfam PF13365 Trypsin-like peptidase domain 107 247 3.2E-33 T 28-03-2018 CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 Gene3D G3DSA:2.40.10.10 174 281 2.2E-36 T 28-03-2018 CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 SUPERFAMILY SSF50494 81 281 7.54E-58 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 PRINTS PR00834 HtrA/DegQ protease family signature 116 128 8.9E-41 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 PRINTS PR00834 HtrA/DegQ protease family signature 178 202 8.9E-41 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 PRINTS PR00834 HtrA/DegQ protease family signature 240 257 8.9E-41 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 PRINTS PR00834 HtrA/DegQ protease family signature 137 157 8.9E-41 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 PRINTS PR00834 HtrA/DegQ protease family signature 218 235 8.9E-41 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS30640 ceffd25e4fd2fa479a3d71eae86a1b8f 283 Gene3D G3DSA:2.40.10.10 77 173 7.6E-33 T 28-03-2018 CNX65_RS26845 ed18739029c609ff39bd5c289862d534 514 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 212 396 2.8E-36 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CNX65_RS26845 ed18739029c609ff39bd5c289862d534 514 Pfam PF17482 Phage tail sheath C-terminal domain 397 503 4.9E-21 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CNX65_RS07190 05ca4d1874d3c7e08f3a2219e1002baa 290 Gene3D G3DSA:1.10.3720.10 15 270 1.4E-40 T 28-03-2018 CNX65_RS07190 05ca4d1874d3c7e08f3a2219e1002baa 290 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 82 265 4.8E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS07190 05ca4d1874d3c7e08f3a2219e1002baa 290 SUPERFAMILY SSF161098 62 265 1.09E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS07190 05ca4d1874d3c7e08f3a2219e1002baa 290 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 66 156 4.3E-22 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 Gene3D G3DSA:3.10.105.10 358 573 4.7E-31 T 28-03-2018 CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 PIRSF PIRSF002741 96 226 3.7E-5 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 PIRSF PIRSF002741 232 603 5.0E-36 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 109 515 2.2E-44 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 Gene3D G3DSA:3.40.190.10 258 357 1.2E-17 T 28-03-2018 CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 SUPERFAMILY SSF53850 64 230 1.99E-63 T 28-03-2018 CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 SUPERFAMILY SSF53850 258 601 1.99E-63 T 28-03-2018 CNX65_RS03755 ef63e36f074f78eba7e4d4f7b0b7ae57 604 Gene3D G3DSA:3.90.76.10 70 236 1.2E-15 T 28-03-2018 CNX65_RS28705 86243a8820b146c0deab815027d96834 239 Pfam PF00027 Cyclic nucleotide-binding domain 39 125 3.7E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS28705 86243a8820b146c0deab815027d96834 239 Pfam PF13545 Crp-like helix-turn-helix domain 158 233 3.9E-13 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS28705 86243a8820b146c0deab815027d96834 239 SMART SM00100 20 138 1.7E-15 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS28705 86243a8820b146c0deab815027d96834 239 SUPERFAMILY SSF51206 26 150 8.77E-22 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS28705 86243a8820b146c0deab815027d96834 239 Gene3D G3DSA:2.60.120.10 18 160 1.4E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS28705 86243a8820b146c0deab815027d96834 239 SUPERFAMILY SSF46785 156 235 5.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28705 86243a8820b146c0deab815027d96834 239 Gene3D G3DSA:1.10.10.10 161 239 4.5E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 Pfam PF00857 Isochorismatase family 32 205 1.2E-41 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 PIRSF PIRSF001111 1 240 3.5E-90 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 SUPERFAMILY SSF52499 1 210 2.09E-61 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 Gene3D G3DSA:3.40.50.850 1 211 3.4E-50 T 28-03-2018 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 PRINTS PR01398 Isochorismatase signature 63 80 8.1E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 PRINTS PR01398 Isochorismatase signature 168 186 8.1E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 PRINTS PR01398 Isochorismatase signature 112 134 8.1E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 PRINTS PR01398 Isochorismatase signature 2 14 8.1E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 PRINTS PR01398 Isochorismatase signature 80 99 8.1E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS15950 0196f9ef61ba407bf6dae39e859b1b74 254 PRINTS PR01398 Isochorismatase signature 186 203 8.1E-44 T 28-03-2018 IPR016291 Isochorismatase GO:0008908 MetaCyc: PWY-5901 CNX65_RS19650 61851afc53761a3139836a29e8a83f06 256 SUPERFAMILY SSF53335 10 161 7.3E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS19650 61851afc53761a3139836a29e8a83f06 256 SUPERFAMILY SSF53335 219 238 7.3E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS19650 61851afc53761a3139836a29e8a83f06 256 Pfam PF13649 Methyltransferase domain 48 150 2.0E-15 T 28-03-2018 CNX65_RS19650 61851afc53761a3139836a29e8a83f06 256 Gene3D G3DSA:3.40.50.150 3 254 1.0E-30 T 28-03-2018 CNX65_RS32250 79e1bde7ddf02a14d5badbab0bc853d4 464 TIGRFAM TIGR03920 T7SS_EccD: type VII secretion integral membrane protein EccD 11 459 2.4E-90 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CNX65_RS32250 79e1bde7ddf02a14d5badbab0bc853d4 464 Pfam PF08817 WXG100 protein secretion system (Wss), protein YukD 9 84 4.8E-22 T 28-03-2018 IPR024962 YukD-like CNX65_RS32250 79e1bde7ddf02a14d5badbab0bc853d4 464 PIRSF PIRSF017804 1 462 2.5E-116 T 28-03-2018 IPR006707 Type VII secretion system membrane protein EccD CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 6 64 5.2E-22 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 SUPERFAMILY SSF46785 4 88 2.02E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 Gene3D G3DSA:1.10.10.10 1 85 1.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 Pfam PF03466 LysR substrate binding domain 87 275 3.2E-14 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 SUPERFAMILY SSF53850 89 281 1.02E-16 T 28-03-2018 CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 Gene3D G3DSA:3.40.190.10 86 175 4.9E-15 T 28-03-2018 CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 Gene3D G3DSA:3.40.190.10 176 256 2.1E-7 T 28-03-2018 CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS25480 ab5118a4a27de43a5eac67c6522a4ea5 298 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.9E-8 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.0E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 2.0E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 77 88 2.0E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 2.0E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 227 247 2.0E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 Gene3D G3DSA:3.40.50.720 2 266 4.1E-37 T 28-03-2018 CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 SUPERFAMILY SSF51735 163 266 6.02E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 SUPERFAMILY SSF51735 8 134 6.02E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 167 263 1.0E-21 T 28-03-2018 CNX65_RS15115 be9f914ae9edcc1b51ef6d02e2ebbd58 272 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 134 9.4E-9 T 28-03-2018 CNX65_RS15855 55c2e1853d7b9255fe70a4c1471bee50 285 PIRSF PIRSF000103 1 281 2.7E-21 T 28-03-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 CNX65_RS15855 55c2e1853d7b9255fe70a4c1471bee50 285 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 7 151 7.7E-8 T 28-03-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0004616|GO:0055114 CNX65_RS15855 55c2e1853d7b9255fe70a4c1471bee50 285 SUPERFAMILY SSF51735 5 155 1.94E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15855 55c2e1853d7b9255fe70a4c1471bee50 285 Gene3D G3DSA:1.10.1040.10 166 282 9.1E-7 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS15855 55c2e1853d7b9255fe70a4c1471bee50 285 Gene3D G3DSA:3.40.50.720 2 165 4.7E-18 T 28-03-2018 CNX65_RS19665 a3b4879dcb034e8c827a165bea1a3576 372 Pfam PF01497 Periplasmic binding protein 83 327 3.9E-15 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS19665 a3b4879dcb034e8c827a165bea1a3576 372 Gene3D G3DSA:3.40.50.1980 194 357 7.9E-32 T 28-03-2018 CNX65_RS19665 a3b4879dcb034e8c827a165bea1a3576 372 SUPERFAMILY SSF53807 57 353 1.1E-35 T 28-03-2018 CNX65_RS19665 a3b4879dcb034e8c827a165bea1a3576 372 Gene3D G3DSA:3.40.50.1980 58 193 1.0E-16 T 28-03-2018 CNX65_RS22125 187fa76d3eadcd8721b3d7f6874fc9a7 230 SUPERFAMILY SSF50800 4 215 1.26E-68 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CNX65_RS22125 187fa76d3eadcd8721b3d7f6874fc9a7 230 Pfam PF03473 MOSC domain 51 161 1.3E-20 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CNX65_RS22125 187fa76d3eadcd8721b3d7f6874fc9a7 230 Gene3D G3DSA:2.40.33.20 1 228 7.6E-53 T 28-03-2018 CNX65_RS16455 f20860cd5ac75a6211fb79948a33e4e4 277 Gene3D G3DSA:1.10.260.40 3 98 4.6E-16 T 28-03-2018 CNX65_RS16455 f20860cd5ac75a6211fb79948a33e4e4 277 SUPERFAMILY SSF47413 35 87 3.56E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS16455 f20860cd5ac75a6211fb79948a33e4e4 277 Pfam PF13560 Helix-turn-helix domain 11 90 1.1E-16 T 28-03-2018 CNX65_RS16455 f20860cd5ac75a6211fb79948a33e4e4 277 SMART SM00530 15 88 4.7E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS06665 8d081a55c829f6d45d78acdd67f34020 204 Pfam PF01569 PAP2 superfamily 114 190 1.1E-9 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS06665 8d081a55c829f6d45d78acdd67f34020 204 Gene3D G3DSA:1.20.144.10 3 197 1.6E-10 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS06665 8d081a55c829f6d45d78acdd67f34020 204 SUPERFAMILY SSF48317 10 195 1.7E-17 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS06665 8d081a55c829f6d45d78acdd67f34020 204 SMART SM00014 85 189 0.0048 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS26275 0fcf9afb35db0530494f6067f8c91fe6 573 Pfam PF00474 Sodium:solute symporter family 34 199 2.6E-27 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS26275 0fcf9afb35db0530494f6067f8c91fe6 573 Pfam PF00474 Sodium:solute symporter family 307 497 6.9E-12 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS26275 0fcf9afb35db0530494f6067f8c91fe6 573 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 479 499 - T 28-03-2018 IPR018212 Sodium/solute symporter, conserved site GO:0005215|GO:0006810|GO:0016020 CNX65_RS33790 d501bc2d3aca8d2888dcd21a27c0cd6f 280 Gene3D G3DSA:3.30.470.10 4 117 4.9E-24 T 28-03-2018 CNX65_RS33790 d501bc2d3aca8d2888dcd21a27c0cd6f 280 Pfam PF01063 Amino-transferase class IV 31 255 3.6E-40 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CNX65_RS33790 d501bc2d3aca8d2888dcd21a27c0cd6f 280 Gene3D G3DSA:3.20.10.10 118 275 3.2E-36 T 28-03-2018 CNX65_RS33790 d501bc2d3aca8d2888dcd21a27c0cd6f 280 SUPERFAMILY SSF56752 6 265 1.14E-55 T 28-03-2018 IPR001544 Aminotransferase class IV GO:0003824|GO:0008152 Reactome: R-HSA-70895 CNX65_RS03715 6d6e56e0a8c721312159e4874834407a 400 Pfam PF03888 MucB/RseB N-terminal domain 89 227 1.7E-5 T 28-03-2018 IPR033434 MucB/RseB, N-terminal CNX65_RS03715 6d6e56e0a8c721312159e4874834407a 400 Gene3D G3DSA:2.50.20.10 48 247 3.1E-34 T 28-03-2018 CNX65_RS03715 6d6e56e0a8c721312159e4874834407a 400 SUPERFAMILY SSF89392 88 245 5.49E-11 T 28-03-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 SUPERFAMILY SSF51206 233 343 2.88E-17 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 Gene3D G3DSA:3.40.50.10140 504 643 1.2E-20 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 Pfam PF13676 TIR domain 514 616 1.5E-18 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 SUPERFAMILY SSF52200 506 631 1.44E-18 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 Gene3D G3DSA:2.60.120.10 231 372 1.7E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 Gene3D G3DSA:3.30.70.1230 1 154 3.1E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 SMART SM00100 235 355 2.6E-7 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 ProSitePatterns PS00888 Cyclic nucleotide-binding domain signature 1. 262 278 - T 28-03-2018 IPR018488 Cyclic nucleotide-binding, conserved site CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 Pfam PF00027 Cyclic nucleotide-binding domain 257 338 5.6E-13 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 SMART SM00255 510 644 3.3E-4 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS30130 6907204b400e093edbf24c639fe71062 644 SUPERFAMILY SSF55073 1 158 9.42E-8 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS31770 65b0803fc3e2e1f92d55d3a082d58cef 264 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 5 261 1.2E-70 T 28-03-2018 CNX65_RS31770 65b0803fc3e2e1f92d55d3a082d58cef 264 Gene3D G3DSA:3.60.10.10 1 263 2.1E-52 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS31770 65b0803fc3e2e1f92d55d3a082d58cef 264 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 4 262 4.0E-73 T 28-03-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 CNX65_RS31770 65b0803fc3e2e1f92d55d3a082d58cef 264 SUPERFAMILY SSF56219 2 262 5.76E-70 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS31770 65b0803fc3e2e1f92d55d3a082d58cef 264 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 6 255 1.2E-22 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS10640 0c06b5fbc57e0d76008591c26e3845d1 364 Pfam PF00067 Cytochrome P450 272 333 1.5E-12 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10640 0c06b5fbc57e0d76008591c26e3845d1 364 SUPERFAMILY SSF48264 268 364 1.01E-24 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10640 0c06b5fbc57e0d76008591c26e3845d1 364 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 305 314 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS10640 0c06b5fbc57e0d76008591c26e3845d1 364 PRINTS PR00359 B-class P450 signature 280 295 1.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10640 0c06b5fbc57e0d76008591c26e3845d1 364 PRINTS PR00359 B-class P450 signature 303 312 1.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10640 0c06b5fbc57e0d76008591c26e3845d1 364 PRINTS PR00359 B-class P450 signature 312 323 1.0E-10 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS10640 0c06b5fbc57e0d76008591c26e3845d1 364 Gene3D G3DSA:1.10.630.10 267 364 2.7E-20 T 28-03-2018 CNX65_RS22205 ef8a324a5c8ae4d49465a3c832eb3304 303 SUPERFAMILY SSF51735 6 251 1.61E-48 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22205 ef8a324a5c8ae4d49465a3c832eb3304 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22205 ef8a324a5c8ae4d49465a3c832eb3304 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22205 ef8a324a5c8ae4d49465a3c832eb3304 303 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 2.6E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22205 ef8a324a5c8ae4d49465a3c832eb3304 303 Pfam PF00106 short chain dehydrogenase 9 205 1.2E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22205 ef8a324a5c8ae4d49465a3c832eb3304 303 Gene3D G3DSA:3.40.50.720 1 300 2.9E-52 T 28-03-2018 CNX65_RS03680 47d2eda6c8f11f59c123f7102dd57f87 97 Gene3D G3DSA:3.30.1360.20 1 95 5.0E-26 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CNX65_RS03680 47d2eda6c8f11f59c123f7102dd57f87 97 SUPERFAMILY SSF55248 1 93 1.11E-24 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CNX65_RS03680 47d2eda6c8f11f59c123f7102dd57f87 97 Pfam PF01329 Pterin 4 alpha carbinolamine dehydratase 4 91 7.4E-25 T 28-03-2018 IPR001533 Transcriptional coactivator/pterin dehydratase GO:0006729|GO:0008124 MetaCyc: PWY-7158 CNX65_RS20875 5e94bdd5fbffa8a8354cc6b64ce5610b 241 Pfam PF07302 AroM protein 13 235 1.1E-78 T 28-03-2018 IPR010843 Uncharacterised protein family AroM CNX65_RS20875 5e94bdd5fbffa8a8354cc6b64ce5610b 241 Gene3D G3DSA:3.40.50.1860 127 237 6.9E-5 T 28-03-2018 CNX65_RS20875 5e94bdd5fbffa8a8354cc6b64ce5610b 241 Gene3D G3DSA:3.40.50.1860 21 107 0.0016 T 28-03-2018 CNX65_RS20875 5e94bdd5fbffa8a8354cc6b64ce5610b 241 ProDom PD037589 AROM ARO OPERON REGULATED BY AROR BIOSYNTHESIS TRANSCRIPTION AMINO AROMATIC 13 212 7.0E-33 T 28-03-2018 IPR010843 Uncharacterised protein family AroM CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:3.40.50.300 4 34 0.013 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 SMART SM00382 28 438 0.47 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 SMART SM00382 506 780 2.6E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 SUPERFAMILY SSF52540 282 454 6.25E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 SUPERFAMILY SSF52540 8 117 6.25E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:3.40.50.300 318 478 9.1E-23 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:3.40.50.300 643 812 4.6E-26 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:1.20.1580.10 564 630 2.2E-11 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Pfam PF00005 ABC transporter 504 732 6.1E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 ProSitePatterns PS00211 ABC transporters family signature. 700 714 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:1.10.8.280 156 278 2.6E-14 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:3.40.50.300 35 44 0.1 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:3.40.50.300 45 95 0.28 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 Gene3D G3DSA:3.40.50.300 485 547 8.3E-6 T 28-03-2018 CNX65_RS18410 5eb5ca45cd633e1fb65896da325313b5 818 SUPERFAMILY SSF52540 502 787 4.38E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS14225 aad87ec0d579319b0bddfcbe83c6c0d1 451 Gene3D G3DSA:3.40.50.2000 1 171 6.3E-5 T 28-03-2018 CNX65_RS14225 aad87ec0d579319b0bddfcbe83c6c0d1 451 Gene3D G3DSA:3.40.50.2000 172 339 2.1E-41 T 28-03-2018 CNX65_RS14225 aad87ec0d579319b0bddfcbe83c6c0d1 451 SUPERFAMILY SSF53756 1 349 6.28E-57 T 28-03-2018 CNX65_RS14225 aad87ec0d579319b0bddfcbe83c6c0d1 451 Pfam PF00534 Glycosyl transferases group 1 169 333 2.1E-29 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS33020 1fd2ec9df4b1e6ed7ef858d9a62f237b 303 Pfam PF00378 Enoyl-CoA hydratase/isomerase 34 298 2.9E-55 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS33020 1fd2ec9df4b1e6ed7ef858d9a62f237b 303 TIGRFAM TIGR01929 menB: naphthoate synthase 23 298 1.6E-130 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CNX65_RS33020 1fd2ec9df4b1e6ed7ef858d9a62f237b 303 Gene3D G3DSA:1.10.12.10 243 291 2.6E-16 T 28-03-2018 IPR014748 Crontonase, C-terminal CNX65_RS33020 1fd2ec9df4b1e6ed7ef858d9a62f237b 303 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 15 302 53.499 T 28-03-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 CNX65_RS33020 1fd2ec9df4b1e6ed7ef858d9a62f237b 303 Gene3D G3DSA:3.90.226.10 7 242 8.5E-70 T 28-03-2018 CNX65_RS33020 1fd2ec9df4b1e6ed7ef858d9a62f237b 303 SUPERFAMILY SSF52096 15 300 4.64E-78 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS28690 5e2f0e617403088d065500cdd0b6beac 255 Pfam PF03883 Peroxide stress protein YaaA 2 231 2.2E-35 T 28-03-2018 IPR005583 Peroxide stress protein YaaA CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 Pfam PF16859 Bacterial transcriptional repressor C-terminal 69 168 4.4E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 SUPERFAMILY SSF46689 3 57 2.27E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 51 8.5E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 6 19 3.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 27 50 3.1E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 Gene3D G3DSA:1.10.357.10 55 176 3.8E-12 T 28-03-2018 CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 Gene3D G3DSA:1.10.10.60 2 54 3.9E-17 T 28-03-2018 CNX65_RS12140 62cf0c7732c48000d995809bf9cf8d29 176 SUPERFAMILY SSF48498 67 175 5.78E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS25740 d4f8a88b5c4973bffa631b26f2f16626 286 Gene3D G3DSA:3.30.470.20 86 272 2.5E-6 T 28-03-2018 CNX65_RS25740 d4f8a88b5c4973bffa631b26f2f16626 286 SUPERFAMILY SSF56059 109 270 1.14E-9 T 28-03-2018 CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 135 159 5.0E-8 T 28-03-2018 CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 105 125 5.0E-8 T 28-03-2018 CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 PRINTS PR01036 Tetracycline resistance protein TetB signature 14 38 5.0E-8 T 28-03-2018 CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 Gene3D G3DSA:1.20.1250.20 5 193 4.3E-35 T 28-03-2018 CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 SUPERFAMILY SSF103473 5 193 3.92E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 SUPERFAMILY SSF103473 251 458 3.92E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 Pfam PF07690 Major Facilitator Superfamily 276 455 3.3E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 Pfam PF07690 Major Facilitator Superfamily 17 192 1.2E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS12910 eb046db21e3ee4f3434a8a3b79f1fe99 477 Gene3D G3DSA:1.20.1250.20 257 467 9.0E-21 T 28-03-2018 CNX65_RS29430 c5bc4108399c499806d6f35b5b13ccfa 215 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 22 163 7.1E-46 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CNX65_RS29430 c5bc4108399c499806d6f35b5b13ccfa 215 SUPERFAMILY SSF50475 2 186 3.34E-56 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS29430 c5bc4108399c499806d6f35b5b13ccfa 215 Gene3D G3DSA:2.30.110.10 21 213 6.2E-45 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS28775 bb49fc6d1ccd0fc83d89f8a5764237df 150 Pfam PF13673 Acetyltransferase (GNAT) domain 50 147 2.3E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS28775 bb49fc6d1ccd0fc83d89f8a5764237df 150 SUPERFAMILY SSF55729 15 148 4.15E-30 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS28775 bb49fc6d1ccd0fc83d89f8a5764237df 150 Gene3D G3DSA:3.40.630.30 7 150 8.4E-24 T 28-03-2018 CNX65_RS12470 d76f2feefaf3c9cacc3c6268a6393f8a 308 Gene3D G3DSA:1.10.3720.10 17 294 2.7E-42 T 28-03-2018 CNX65_RS12470 d76f2feefaf3c9cacc3c6268a6393f8a 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 119 304 3.4E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12470 d76f2feefaf3c9cacc3c6268a6393f8a 308 SUPERFAMILY SSF161098 98 286 5.36E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS00570 2b1f0fd523becae8b1423ee33a06a633 387 SUPERFAMILY SSF56059 8 167 4.59E-71 T 28-03-2018 CNX65_RS00570 2b1f0fd523becae8b1423ee33a06a633 387 SUPERFAMILY SSF56059 270 384 4.59E-71 T 28-03-2018 CNX65_RS00570 2b1f0fd523becae8b1423ee33a06a633 387 SUPERFAMILY SSF52440 175 283 3.74E-33 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS00570 2b1f0fd523becae8b1423ee33a06a633 387 Pfam PF03738 Glutathionylspermidine synthase preATP-grasp 12 385 1.5E-145 T 28-03-2018 IPR005494 Glutathionylspermidine synthase, pre-ATP-grasp-like domain CNX65_RS12510 9522328c850809653af44e493e8683a5 398 Gene3D G3DSA:1.20.1250.20 200 391 6.0E-24 T 28-03-2018 CNX65_RS12510 9522328c850809653af44e493e8683a5 398 SUPERFAMILY SSF103473 6 380 3.79E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12510 9522328c850809653af44e493e8683a5 398 Gene3D G3DSA:1.20.1250.20 1 198 1.1E-19 T 28-03-2018 CNX65_RS12510 9522328c850809653af44e493e8683a5 398 Pfam PF07690 Major Facilitator Superfamily 214 395 6.3E-20 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS12510 9522328c850809653af44e493e8683a5 398 Pfam PF07690 Major Facilitator Superfamily 18 197 7.3E-17 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 SMART SM00327 492 668 1.9E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 Pfam PF01078 Magnesium chelatase, subunit ChlI 118 187 2.5E-9 T 28-03-2018 IPR000523 Magnesium chelatase ChlI domain CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 SMART SM00382 28 210 2.2E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 Gene3D G3DSA:3.40.50.410 480 674 5.7E-26 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 SUPERFAMILY SSF53300 495 660 8.16E-23 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 SUPERFAMILY SSF52540 5 332 1.04E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 Gene3D G3DSA:1.10.8.80 252 340 6.5E-24 T 28-03-2018 CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 TIGRFAM TIGR02442 Cob-chelat-sub: cobaltochelatase subunit 5 660 6.6E-240 T 28-03-2018 IPR012804 Cobaltochelatase subunit, putative CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 Gene3D G3DSA:3.40.50.300 2 207 2.8E-22 T 28-03-2018 CNX65_RS28755 efd2acc60195cb5239bfd1fcf73ff9a9 677 Pfam PF13519 von Willebrand factor type A domain 495 601 4.8E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 SMART SM00493 1 113 9.6E-38 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Pfam PF01751 Toprim domain 1 122 3.7E-29 T 28-03-2018 IPR006171 TOPRIM domain CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 SMART SM00437 273 543 1.3E-118 T 28-03-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Pfam PF13368 Topoisomerase C-terminal repeat 751 804 1.1E-17 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Pfam PF13368 Topoisomerase C-terminal repeat 685 746 7.3E-14 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Pfam PF13368 Topoisomerase C-terminal repeat 817 869 1.0E-20 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Pfam PF13368 Topoisomerase C-terminal repeat 627 679 1.2E-8 T 28-03-2018 IPR025589 Topoisomerase C-terminal repeat CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 1 646 6.5E-246 T 28-03-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 1.3E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 506 520 1.3E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 87 100 1.3E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 394 410 1.3E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 171 189 1.3E-35 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 SMART SM00436 113 201 1.2E-43 T 28-03-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Hamap MF_00952 DNA topoisomerase 1 [topA]. 1 763 53.287 T 28-03-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Gene3D G3DSA:1.10.460.10 144 347 4.3E-43 T 28-03-2018 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Gene3D G3DSA:2.70.20.10 348 478 2.1E-37 T 28-03-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Pfam PF01131 DNA topoisomerase 138 580 5.2E-118 T 28-03-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 SUPERFAMILY SSF56712 1 584 2.88E-174 T 28-03-2018 IPR023405 DNA topoisomerase, type IA, core domain CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 28-03-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Gene3D G3DSA:1.10.460.10 479 902 1.5E-30 T 28-03-2018 CNX65_RS01500 4ce4afdb4c21d02c920905c03a1d72b5 903 Gene3D G3DSA:3.40.50.140 1 138 8.1E-39 T 28-03-2018 CNX65_RS25845 03c5ab4432070c742cf34a12d29c0ef4 114 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 17 113 25.107 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CNX65_RS25845 03c5ab4432070c742cf34a12d29c0ef4 114 ProSitePatterns PS00202 Rubredoxin signature. 51 61 - T 28-03-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 CNX65_RS25845 03c5ab4432070c742cf34a12d29c0ef4 114 Pfam PF13397 RNA polymerase-binding protein 5 108 1.1E-42 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CNX65_RS17340 81a482695034ef4194027ccac1ed1b52 272 Pfam PF11296 Protein of unknown function (DUF3097) 6 268 5.8E-120 T 28-03-2018 IPR021447 Protein of unknown function DUF3097 CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Gene3D G3DSA:2.60.40.10 43 159 4.4E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Gene3D G3DSA:2.60.40.10 260 384 2.1E-21 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Gene3D G3DSA:2.60.40.10 163 256 2.3E-18 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Pfam PF17210 SdrD B-like domain 169 242 1.9E-14 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Pfam PF17210 SdrD B-like domain 265 384 2.5E-22 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Pfam PF17210 SdrD B-like domain 48 128 1.7E-8 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 SUPERFAMILY SSF117074 45 127 1.44E-10 T 28-03-2018 CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 SUPERFAMILY SSF117074 256 336 4.18E-16 T 28-03-2018 CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 585 626 9.1E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 SUPERFAMILY SSF117074 166 242 5.36E-17 T 28-03-2018 CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Gene3D G3DSA:2.60.40.10 558 757 2.1E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21895 7cf0dab9e491d9a95f8685d64902794f 816 Gene3D G3DSA:2.60.40.10 385 516 2.4E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS33175 71987aa5dcb9c9db9de0ebe5f6fd41c5 216 Gene3D G3DSA:2.30.180.10 81 212 6.3E-31 T 28-03-2018 IPR000782 FAS1 domain CNX65_RS33175 71987aa5dcb9c9db9de0ebe5f6fd41c5 216 SMART SM00554 117 214 3.2E-22 T 28-03-2018 IPR000782 FAS1 domain CNX65_RS33175 71987aa5dcb9c9db9de0ebe5f6fd41c5 216 SUPERFAMILY SSF82153 80 214 1.83E-30 T 28-03-2018 IPR000782 FAS1 domain CNX65_RS33175 71987aa5dcb9c9db9de0ebe5f6fd41c5 216 Pfam PF02469 Fasciclin domain 93 213 1.0E-28 T 28-03-2018 IPR000782 FAS1 domain CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 Pfam PF06441 Epoxide hydrolase N terminus 25 129 1.5E-35 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 PRINTS PR00412 Epoxide hydrolase signature 381 403 2.4E-13 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 PRINTS PR00412 Epoxide hydrolase signature 149 164 2.4E-13 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 PRINTS PR00412 Epoxide hydrolase signature 194 207 2.4E-13 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 PRINTS PR00412 Epoxide hydrolase signature 208 221 2.4E-13 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 PRINTS PR00412 Epoxide hydrolase signature 120 138 2.4E-13 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 SUPERFAMILY SSF53474 22 403 6.55E-93 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 Gene3D G3DSA:3.40.50.1820 22 410 6.6E-76 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20490 58d57aa35e154c16ebdecc2b807a0536 410 PIRSF PIRSF001112 2 410 6.8E-114 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CNX65_RS23520 9de4fd8ec8abaa04427417de1d5248ad 85 Gene3D G3DSA:3.10.20.30 1 78 1.5E-8 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS23520 9de4fd8ec8abaa04427417de1d5248ad 85 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 3 81 1.7E-24 T 28-03-2018 CNX65_RS23520 9de4fd8ec8abaa04427417de1d5248ad 85 SUPERFAMILY SSF54292 4 82 1.15E-18 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 Gene3D G3DSA:3.40.50.720 148 233 1.6E-23 T 28-03-2018 CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 150 171 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 Gene3D G3DSA:3.90.180.10 234 319 1.0E-7 T 28-03-2018 CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 Gene3D G3DSA:3.90.180.10 1 147 1.2E-44 T 28-03-2018 CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 SMART SM00829 14 316 3.7E-38 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 Pfam PF13602 Zinc-binding dehydrogenase 192 316 5.7E-26 T 28-03-2018 CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 SUPERFAMILY SSF50129 3 154 7.46E-38 T 28-03-2018 IPR011032 GroES-like CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 SUPERFAMILY SSF51735 122 243 8.63E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12480 c03a604973d74337b5bf0f1eaf479d8f 319 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 31 98 1.0E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS31220 e7437a6600970c771ce26f0b1b5e59ba 364 Pfam PF13439 Glycosyltransferase Family 4 21 181 1.1E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS31220 e7437a6600970c771ce26f0b1b5e59ba 364 Pfam PF13692 Glycosyl transferases group 1 203 324 3.5E-18 T 28-03-2018 CNX65_RS31220 e7437a6600970c771ce26f0b1b5e59ba 364 Gene3D G3DSA:3.40.50.2000 192 349 1.1E-30 T 28-03-2018 CNX65_RS31220 e7437a6600970c771ce26f0b1b5e59ba 364 SUPERFAMILY SSF53756 18 361 1.39E-57 T 28-03-2018 CNX65_RS31220 e7437a6600970c771ce26f0b1b5e59ba 364 Gene3D G3DSA:3.40.50.2000 17 191 6.1E-4 T 28-03-2018 CNX65_RS07160 dd2b68cafff4636e4902237e945eb068 307 Pfam PF16868 NMT1-like family 30 304 1.1E-49 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS07160 dd2b68cafff4636e4902237e945eb068 307 SUPERFAMILY SSF53850 27 304 4.21E-56 T 28-03-2018 CNX65_RS07160 dd2b68cafff4636e4902237e945eb068 307 Gene3D G3DSA:3.40.190.10 23 147 7.4E-14 T 28-03-2018 CNX65_RS07160 dd2b68cafff4636e4902237e945eb068 307 Gene3D G3DSA:3.40.190.10 153 307 6.4E-32 T 28-03-2018 CNX65_RS07160 dd2b68cafff4636e4902237e945eb068 307 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 4 305 3.4E-62 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS07330 8a8ce55d0a79ed1e721c7479959ec472 142 SUPERFAMILY SSF55729 4 134 9.94E-20 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS07330 8a8ce55d0a79ed1e721c7479959ec472 142 Pfam PF00583 Acetyltransferase (GNAT) family 58 130 1.9E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS07330 8a8ce55d0a79ed1e721c7479959ec472 142 Gene3D G3DSA:3.40.630.30 1 138 5.2E-19 T 28-03-2018 CNX65_RS11385 00be30a4513d3b33caa6a31f634eab14 822 Pfam PF02687 FtsX-like permease family 725 815 2.9E-7 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS11385 00be30a4513d3b33caa6a31f634eab14 822 Gene3D G3DSA:3.30.530.20 546 705 0.002 T 28-03-2018 IPR023393 START-like domain CNX65_RS02600 ee6c54b8fd0f3491074e63241a9feb7e 266 Pfam PF01061 ABC-2 type transporter 14 219 7.4E-27 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS02600 ee6c54b8fd0f3491074e63241a9feb7e 266 PIRSF PIRSF006648 10 263 8.5E-25 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 Gene3D G3DSA:3.40.50.10810 558 769 8.1E-49 T 28-03-2018 CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 Gene3D G3DSA:3.40.50.300 843 1003 4.8E-31 T 28-03-2018 CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 Pfam PF00176 SNF2 family N-terminal domain 574 837 1.7E-55 T 28-03-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 SMART SM00487 553 737 1.1E-29 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 SMART SM00490 881 965 4.9E-20 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 SUPERFAMILY SSF52540 548 768 1.72E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 SUPERFAMILY SSF52540 772 1022 1.02E-62 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 Pfam PF00271 Helicase conserved C-terminal domain 854 965 8.6E-15 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS05255 67a0c99374c7f5a69736b985e299189a 1028 Pfam PF12419 SNF2 Helicase protein 292 440 2.3E-40 T 28-03-2018 IPR022138 Helicase SWF/SNF-related CNX65_RS31670 f5b1a51f0a2200e59ebb9e35bf98dae4 555 Gene3D G3DSA:1.10.287.1060 85 161 1.5E-5 T 28-03-2018 CNX65_RS26645 60832660b9dab54eda4437467ff6fa3c 171 SUPERFAMILY SSF46785 26 159 1.89E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26645 60832660b9dab54eda4437467ff6fa3c 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 4.2E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS26645 60832660b9dab54eda4437467ff6fa3c 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 136 156 4.2E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS26645 60832660b9dab54eda4437467ff6fa3c 171 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 4.2E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS26645 60832660b9dab54eda4437467ff6fa3c 171 Gene3D G3DSA:1.10.10.10 19 169 5.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26645 60832660b9dab54eda4437467ff6fa3c 171 SMART SM00347 45 146 7.8E-18 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS26645 60832660b9dab54eda4437467ff6fa3c 171 Pfam PF01047 MarR family 52 111 3.0E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS25980 ec4acbf006791305f1830b4eaa21e446 702 Gene3D G3DSA:1.25.40.10 356 573 5.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS25980 ec4acbf006791305f1830b4eaa21e446 702 Gene3D G3DSA:1.25.40.10 104 354 3.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS07520 7c7d1e7f9a6d2b010d2fbbcc8e07198b 125 PIRSF PIRSF006910 1 124 2.9E-51 T 28-03-2018 IPR016499 Nucleic acid binding protein, Rv2694c, predicted CNX65_RS07520 7c7d1e7f9a6d2b010d2fbbcc8e07198b 125 Gene3D G3DSA:2.40.50.140 37 125 2.1E-9 T 28-03-2018 CNX65_RS03760 89b426db42f32ea75d2099a52c6cda3f 332 Gene3D G3DSA:1.10.3720.10 2 319 2.2E-40 T 28-03-2018 CNX65_RS03760 89b426db42f32ea75d2099a52c6cda3f 332 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 330 5.6E-35 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03760 89b426db42f32ea75d2099a52c6cda3f 332 SUPERFAMILY SSF161098 93 162 2.29E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03760 89b426db42f32ea75d2099a52c6cda3f 332 SUPERFAMILY SSF161098 194 318 2.29E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 2.6E-97 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 Gene3D G3DSA:1.20.210.10 24 536 5.1E-192 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 SUPERFAMILY SSF81442 26 535 1.1E-173 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 5.4E-214 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CNX65_RS18645 63ac98e347306bf9aedb571853ee76ce 602 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 37 479 3.9E-147 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS13480 34bd2b19d1b63e6d40a27317cef87951 121 Gene3D G3DSA:2.60.120.10 3 121 1.1E-20 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS13480 34bd2b19d1b63e6d40a27317cef87951 121 SUPERFAMILY SSF51182 7 111 4.28E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS13480 34bd2b19d1b63e6d40a27317cef87951 121 Pfam PF07883 Cupin domain 37 104 5.2E-12 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CNX65_RS11400 955d31f4fd5971f214d2ecbdd5cb6903 282 Hamap MF_02113_B Proteasome subunit beta [prcB]. 10 282 49.099 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CNX65_RS11400 955d31f4fd5971f214d2ecbdd5cb6903 282 TIGRFAM TIGR03690 20S_bact_beta: proteasome, beta subunit 51 276 2.0E-109 T 28-03-2018 IPR022483 Peptidase T1A, proteasome beta-subunit, actinobacteria GO:0004298|GO:0005839|GO:0010498 CNX65_RS11400 955d31f4fd5971f214d2ecbdd5cb6903 282 SUPERFAMILY SSF56235 41 269 5.9E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS11400 955d31f4fd5971f214d2ecbdd5cb6903 282 Pfam PF00227 Proteasome subunit 53 238 1.5E-31 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CNX65_RS11400 955d31f4fd5971f214d2ecbdd5cb6903 282 Gene3D G3DSA:3.60.20.10 50 281 2.9E-42 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 Gene3D G3DSA:3.40.50.720 2 38 1.2E-7 T 28-03-2018 CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 Gene3D G3DSA:3.40.50.720 39 234 5.8E-64 T 28-03-2018 CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 SUPERFAMILY SSF51735 3 230 3.48E-77 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 120 128 6.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 140 159 6.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 67 78 6.1E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 4 21 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 114 130 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 140 159 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 67 78 1.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 127 155 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 3 176 9.1E-7 T 28-03-2018 CNX65_RS11125 d62f346277ab5e6d9bcf2b758257f62b 234 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 230 3.5E-58 T 28-03-2018 CNX65_RS02115 e794da68e2691f41f260cf2350171f5c 272 SUPERFAMILY SSF53335 12 224 2.66E-54 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS02115 e794da68e2691f41f260cf2350171f5c 272 Gene3D G3DSA:3.40.50.150 3 219 9.0E-37 T 28-03-2018 CNX65_RS02115 e794da68e2691f41f260cf2350171f5c 272 PIRSF PIRSF028177 1 272 9.3E-63 T 28-03-2018 IPR016874 Tetracenomycin polyketide synthesis O-methyltransferase TcmP GO:0017000|GO:1901106 CNX65_RS02115 e794da68e2691f41f260cf2350171f5c 272 Pfam PF04072 Leucine carboxyl methyltransferase 57 174 6.7E-16 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 SMART SM00304 203 265 1.0E-4 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 383 493 1.0E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 474 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 449 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 435 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 PRINTS PR00344 Bacterial sensor protein C-terminal signature 479 492 4.2E-14 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 SMART SM00388 273 340 1.5E-20 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 SUPERFAMILY SSF47384 262 341 2.16E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 Pfam PF00512 His Kinase A (phospho-acceptor) domain 275 340 8.8E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 SUPERFAMILY SSF55874 329 492 5.24E-38 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 SMART SM00387 383 494 1.7E-37 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 Pfam PF00672 HAMP domain 203 259 3.7E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 Gene3D G3DSA:3.30.565.10 355 494 2.9E-39 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS08595 0577dc16b2bffdbd8e4f11fedc8fc5d8 494 Gene3D G3DSA:1.10.287.130 262 336 6.0E-16 T 28-03-2018 CNX65_RS07425 cefb3adf6b18acc8c12be687a655c96b 302 Hamap MF_01876 Pseudouridine-5'-phosphate glycosidase [psuG]. 8 302 39.239 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CNX65_RS07425 cefb3adf6b18acc8c12be687a655c96b 302 SUPERFAMILY SSF110581 7 301 4.58E-101 T 28-03-2018 CNX65_RS07425 cefb3adf6b18acc8c12be687a655c96b 302 Gene3D G3DSA:3.40.1790.10 2 302 1.4E-125 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CNX65_RS07425 cefb3adf6b18acc8c12be687a655c96b 302 Pfam PF04227 Indigoidine synthase A like protein 9 299 5.8E-117 T 28-03-2018 IPR007342 Pseudouridine-5'-phosphate glycosidase GO:0016798 KEGG: 00240+4.2.1.70|MetaCyc: PWY-6019 CNX65_RS29370 17e356bc5a1b6afe7c45f0f4bb5fb224 63 Gene3D G3DSA:2.30.170.40 2 63 1.7E-22 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29370 17e356bc5a1b6afe7c45f0f4bb5fb224 63 Pfam PF00830 Ribosomal L28 family 4 59 6.5E-23 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29370 17e356bc5a1b6afe7c45f0f4bb5fb224 63 TIGRFAM TIGR00009 L28: ribosomal protein bL28 2 57 1.6E-22 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29370 17e356bc5a1b6afe7c45f0f4bb5fb224 63 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 63 17.788 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29370 17e356bc5a1b6afe7c45f0f4bb5fb224 63 SUPERFAMILY SSF143800 2 62 2.55E-23 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS27610 e66e60bcb5a5774c05cf00dbf21d0b4c 126 Pfam PF01042 Endoribonuclease L-PSP 15 123 8.2E-23 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CNX65_RS27610 e66e60bcb5a5774c05cf00dbf21d0b4c 126 SUPERFAMILY SSF55298 1 124 2.2E-34 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS27610 e66e60bcb5a5774c05cf00dbf21d0b4c 126 Gene3D G3DSA:3.30.1330.40 1 126 1.8E-32 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS31245 cba0a433f82fe7816e1c3dbb0ef332e5 230 SUPERFAMILY SSF56801 2 225 1.44E-17 T 28-03-2018 CNX65_RS31245 cba0a433f82fe7816e1c3dbb0ef332e5 230 Gene3D G3DSA:3.40.50.980 1 113 5.0E-10 T 28-03-2018 CNX65_RS31245 cba0a433f82fe7816e1c3dbb0ef332e5 230 TIGRFAM TIGR03089 TIGR03089: TIGR03089 family protein 12 225 5.8E-52 T 28-03-2018 IPR017523 Conserved hypothetical protein CHP03089 CNX65_RS31245 cba0a433f82fe7816e1c3dbb0ef332e5 230 Gene3D G3DSA:3.40.50.980 155 227 0.009 T 28-03-2018 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 ProSitePatterns PS00211 ABC transporters family signature. 424 438 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 ProSitePatterns PS00211 ABC transporters family signature. 161 175 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 Gene3D G3DSA:3.40.50.300 10 277 2.0E-62 T 28-03-2018 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 Gene3D G3DSA:3.40.50.300 282 543 1.1E-65 T 28-03-2018 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 SUPERFAMILY SSF52540 285 523 2.95E-63 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 Pfam PF00005 ABC transporter 34 188 2.2E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 Pfam PF00005 ABC transporter 302 452 7.8E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 SMART SM00382 42 246 1.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 SMART SM00382 310 501 1.3E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 SUPERFAMILY SSF52540 13 259 5.68E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 503 536 3.1E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS17585 0b18059c1b995b03db4d33d3c68c6116 549 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 240 272 0.015 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS28610 54774c442c86f5e1e8fb4f79ee19b0e9 98 Gene3D G3DSA:3.30.70.1120 2 92 1.0E-31 T 28-03-2018 CNX65_RS28610 54774c442c86f5e1e8fb4f79ee19b0e9 98 Pfam PF04456 Protein of unknown function (DUF503) 3 89 2.3E-30 T 28-03-2018 IPR007546 Protein of unknown function DUF503 CNX65_RS28610 54774c442c86f5e1e8fb4f79ee19b0e9 98 SUPERFAMILY SSF103007 2 94 1.28E-28 T 28-03-2018 IPR007546 Protein of unknown function DUF503 CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 Gene3D G3DSA:3.30.70.920 54 135 5.4E-18 T 28-03-2018 CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 Pfam PF13404 AsnC-type helix-turn-helix domain 2 41 1.4E-14 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.5E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.5E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.5E-10 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 SUPERFAMILY SSF46785 1 61 2.03E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 Gene3D G3DSA:1.10.10.10 2 53 1.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 Pfam PF01037 Lrp/AsnC ligand binding domain 67 138 5.9E-13 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 SUPERFAMILY SSF54909 61 144 1.47E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 SMART SM00344 1 108 4.1E-34 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS32830 735d94a49f63a41894b43a7e53aa94cc 146 ProSitePatterns PS00519 AsnC-type HTH domain signature. 19 45 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 SUPERFAMILY SSF89372 583 719 5.23E-7 T 28-03-2018 CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 Gene3D G3DSA:2.120.10.70 110 175 0.088 T 28-03-2018 CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 Gene3D G3DSA:2.120.10.70 319 578 8.0E-11 T 28-03-2018 CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 Gene3D G3DSA:2.120.10.70 579 729 2.0E-14 T 28-03-2018 CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 SUPERFAMILY SSF89372 381 604 1.96E-11 T 28-03-2018 CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 SUPERFAMILY SSF50934 132 183 3.92E-6 T 28-03-2018 IPR023294 Tachylectin 2 CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 SUPERFAMILY SSF50934 233 344 3.92E-6 T 28-03-2018 IPR023294 Tachylectin 2 CNX65_RS19620 f67184d7fdc88a5a2e79082c8b31665f 731 Pfam PF14517 Tachylectin 130 339 2.6E-19 T 28-03-2018 IPR023294 Tachylectin 2 CNX65_RS11335 4017bace08cc57d82c35b6eb50e8b74f 275 Gene3D G3DSA:3.10.330.20 2 68 2.9E-26 T 28-03-2018 CNX65_RS11335 4017bace08cc57d82c35b6eb50e8b74f 275 SUPERFAMILY SSF53335 7 258 4.22E-70 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS11335 4017bace08cc57d82c35b6eb50e8b74f 275 PIRSF PIRSF017269 2 269 2.9E-84 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CNX65_RS11335 4017bace08cc57d82c35b6eb50e8b74f 275 Gene3D G3DSA:3.40.50.150 70 264 1.1E-33 T 28-03-2018 CNX65_RS11335 4017bace08cc57d82c35b6eb50e8b74f 275 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 74 235 5.4E-20 T 28-03-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829 CNX65_RS11335 4017bace08cc57d82c35b6eb50e8b74f 275 Pfam PF14801 tRNA methyltransferase complex GCD14 subunit N-term 5 55 1.0E-29 T 28-03-2018 CNX65_RS33870 864fa55b61ecb1201e157d18c52815d4 284 SUPERFAMILY SSF51658 22 282 4.42E-47 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS33870 864fa55b61ecb1201e157d18c52815d4 284 Pfam PF01261 Xylose isomerase-like TIM barrel 29 232 1.9E-27 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS33870 864fa55b61ecb1201e157d18c52815d4 284 Gene3D G3DSA:3.20.20.150 1 284 3.7E-49 T 28-03-2018 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 SUPERFAMILY SSF47413 2 61 5.91E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 Gene3D G3DSA:3.40.50.2300 59 175 1.9E-30 T 28-03-2018 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 SMART SM00354 3 73 3.7E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 Pfam PF13377 Periplasmic binding protein-like domain 171 338 2.2E-35 T 28-03-2018 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 5 15 6.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 15 25 6.0E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 SUPERFAMILY SSF53822 64 339 2.69E-61 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 28-03-2018 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 Gene3D G3DSA:1.10.260.40 4 58 1.7E-22 T 28-03-2018 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 50 4.4E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09620 08dc76bb3637d250f581633af8a0f1b1 359 Gene3D G3DSA:3.40.50.2300 176 323 1.4E-42 T 28-03-2018 CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 Pfam PF04542 Sigma-70 region 2 17 79 3.6E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 SUPERFAMILY SSF88659 96 161 1.5E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 TIGRFAM TIGR02983 SigE-fam_strep: RNA polymerase sigma-70 factor, sigma-E family 3 161 2.1E-46 T 28-03-2018 IPR014325 RNA polymerase sigma-E factor, actinobacteria GO:0016987 CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 SUPERFAMILY SSF88946 3 93 1.61E-15 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 Gene3D G3DSA:1.10.10.10 89 166 3.8E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 Pfam PF08281 Sigma-70, region 4 104 156 1.5E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 9 160 1.8E-21 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS34070 ebb6cf5d7b7887d840178a4bfe874f3f 171 Gene3D G3DSA:1.10.1740.10 1 88 4.7E-16 T 28-03-2018 CNX65_RS22505 532195198653f8690e01eb82dfaca36d 102 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 6 99 2.5E-12 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CNX65_RS22505 532195198653f8690e01eb82dfaca36d 102 Gene3D G3DSA:1.10.287.1060 2 102 1.2E-6 T 28-03-2018 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 Gene3D G3DSA:2.40.50.140 998 1093 5.7E-9 T 28-03-2018 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 SUPERFAMILY SSF89550 5 91 1.31E-29 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 SUPERFAMILY SSF89550 132 267 1.31E-29 T 28-03-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 SMART SM00481 6 73 1.0E-29 T 28-03-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 Pfam PF14579 Helix-hairpin-helix motif 830 917 2.2E-27 T 28-03-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 5 1054 0.0 T 28-03-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 315 757 1.3E-157 T 28-03-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 Gene3D G3DSA:1.10.150.280 807 915 4.7E-12 T 28-03-2018 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 Pfam PF02811 PHP domain 7 193 2.0E-44 T 28-03-2018 IPR004013 PHP domain GO:0003824 CNX65_RS28145 93a02c970467a26d4ef2300167a0c46a 1176 Gene3D G3DSA:3.20.20.140 2 259 1.7E-48 T 28-03-2018 CNX65_RS12405 c512f3a1026cfb43d17946d20d3f6857 312 Gene3D G3DSA:3.90.180.10 1 312 1.2E-66 T 28-03-2018 CNX65_RS12405 c512f3a1026cfb43d17946d20d3f6857 312 SUPERFAMILY SSF51735 117 286 1.86E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12405 c512f3a1026cfb43d17946d20d3f6857 312 SUPERFAMILY SSF50129 1 145 2.59E-31 T 28-03-2018 IPR011032 GroES-like CNX65_RS12405 c512f3a1026cfb43d17946d20d3f6857 312 SMART SM00829 10 309 2.2E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS12405 c512f3a1026cfb43d17946d20d3f6857 312 Pfam PF13602 Zinc-binding dehydrogenase 187 309 1.9E-21 T 28-03-2018 CNX65_RS12405 c512f3a1026cfb43d17946d20d3f6857 312 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 1.9E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS12405 c512f3a1026cfb43d17946d20d3f6857 312 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 145 166 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS30010 e870aa65e96a4bdf705cee81bb54f3f7 134 Gene3D G3DSA:2.30.110.10 3 130 2.0E-12 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS30010 e870aa65e96a4bdf705cee81bb54f3f7 134 Pfam PF12900 Pyridoxamine 5'-phosphate oxidase 12 129 2.1E-21 T 28-03-2018 IPR024747 Pyridoxamine 5'-phosphate oxidase-related CNX65_RS30010 e870aa65e96a4bdf705cee81bb54f3f7 134 SUPERFAMILY SSF50475 7 130 8.35E-18 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS14595 8613357f95d7cce973d1a50f0480ebae 66 Gene3D G3DSA:3.30.70.20 1 65 1.2E-8 T 28-03-2018 CNX65_RS14595 8613357f95d7cce973d1a50f0480ebae 66 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 6.3E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS14595 8613357f95d7cce973d1a50f0480ebae 66 PRINTS PR00352 3Fe-4S ferredoxin signature 48 60 6.3E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS14595 8613357f95d7cce973d1a50f0480ebae 66 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 6.3E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS14595 8613357f95d7cce973d1a50f0480ebae 66 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 60 1.7E-13 T 28-03-2018 CNX65_RS14595 8613357f95d7cce973d1a50f0480ebae 66 SUPERFAMILY SSF54862 2 62 1.79E-14 T 28-03-2018 CNX65_RS17750 cd6ed4c78d48d7e6f7f0c132f212505b 455 Pfam PF13489 Methyltransferase domain 266 418 1.2E-11 T 28-03-2018 CNX65_RS17750 cd6ed4c78d48d7e6f7f0c132f212505b 455 Gene3D G3DSA:3.40.50.150 244 455 5.4E-38 T 28-03-2018 CNX65_RS17750 cd6ed4c78d48d7e6f7f0c132f212505b 455 Pfam PF12623 RNA repair, ligase-Pnkp-associating, region of Hen1 1 229 7.0E-99 T 28-03-2018 IPR024740 Hen1, N-terminal CNX65_RS17750 cd6ed4c78d48d7e6f7f0c132f212505b 455 TIGRFAM TIGR04074 bacter_Hen1: 3' terminal RNA ribose 2'-O-methyltransferase Hen1 2 449 2.1E-198 T 28-03-2018 IPR024026 3'-RNA ribose 2'-O-methyltransferase, Hen1, bacterial CNX65_RS17750 cd6ed4c78d48d7e6f7f0c132f212505b 455 SUPERFAMILY SSF53335 258 418 1.0E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 Gene3D G3DSA:3.90.1150.10 421 594 1.5E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 SUPERFAMILY SSF56112 82 145 1.39E-24 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 SUPERFAMILY SSF56112 186 352 1.39E-24 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 Gene3D G3DSA:1.10.510.10 230 420 3.3E-8 T 28-03-2018 CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 Pfam PF00202 Aminotransferase class-III 467 810 8.2E-48 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 SUPERFAMILY SSF53383 446 870 1.57E-89 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 Pfam PF03109 ABC1 family 100 217 2.9E-26 T 28-03-2018 IPR004147 UbiB domain CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 Gene3D G3DSA:3.30.200.20 92 229 3.7E-23 T 28-03-2018 CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 671 707 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 Gene3D G3DSA:3.90.1150.10 754 870 3.7E-7 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS15850 170cbe1f77006cd989d2ddafa5dc918c 878 Gene3D G3DSA:3.40.640.10 605 753 7.2E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS08425 edc39e2d9eb88d591c270582362b5b10 182 Pfam PF04978 Protein of unknown function (DUF664) 20 177 1.2E-42 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CNX65_RS08425 edc39e2d9eb88d591c270582362b5b10 182 SUPERFAMILY SSF109854 11 176 3.82E-35 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS08425 edc39e2d9eb88d591c270582362b5b10 182 Gene3D G3DSA:1.20.120.450 1 181 1.9E-32 T 28-03-2018 CNX65_RS04150 c905ac13ee0a8a59b25a82753a88d4b0 241 Gene3D G3DSA:3.40.50.1400 109 222 2.0E-16 T 28-03-2018 CNX65_RS04150 c905ac13ee0a8a59b25a82753a88d4b0 241 SUPERFAMILY SSF53800 7 228 5.89E-21 T 28-03-2018 CNX65_RS04150 c905ac13ee0a8a59b25a82753a88d4b0 241 Gene3D G3DSA:3.40.50.1400 4 108 8.6E-20 T 28-03-2018 CNX65_RS04150 c905ac13ee0a8a59b25a82753a88d4b0 241 Pfam PF01903 CbiX 12 98 1.6E-13 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CNX65_RS28710 2c0e9a43adb33a1dfa0d3658ae305591 301 SMART SM00090 64 293 6.1E-8 T 28-03-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|Reactome: R-HSA-6791226 CNX65_RS28710 2c0e9a43adb33a1dfa0d3658ae305591 301 Pfam PF01163 RIO1 family 126 281 2.0E-31 T 28-03-2018 CNX65_RS28710 2c0e9a43adb33a1dfa0d3658ae305591 301 Gene3D G3DSA:1.10.510.10 190 286 8.0E-7 T 28-03-2018 CNX65_RS28710 2c0e9a43adb33a1dfa0d3658ae305591 301 Gene3D G3DSA:3.30.200.20 75 188 2.8E-19 T 28-03-2018 CNX65_RS28710 2c0e9a43adb33a1dfa0d3658ae305591 301 SUPERFAMILY SSF56112 79 118 8.34E-16 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS28710 2c0e9a43adb33a1dfa0d3658ae305591 301 SUPERFAMILY SSF56112 153 292 8.34E-16 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS13450 e78e57766a87bb466f95dba6227c74b2 231 Gene3D G3DSA:3.30.70.1210 95 219 5.5E-29 T 28-03-2018 CNX65_RS13450 e78e57766a87bb466f95dba6227c74b2 231 Pfam PF08798 CRISPR associated protein 2 219 9.3E-59 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 CNX65_RS13450 e78e57766a87bb466f95dba6227c74b2 231 Gene3D G3DSA:3.30.70.1200 1 91 2.6E-18 T 28-03-2018 CNX65_RS13450 e78e57766a87bb466f95dba6227c74b2 231 SUPERFAMILY SSF117987 96 219 2.38E-27 T 28-03-2018 CNX65_RS13450 e78e57766a87bb466f95dba6227c74b2 231 TIGRFAM TIGR01907 casE_Cse3: CRISPR-associated protein Cas6/Cse3/CasE, subtype I-E/ECOLI 23 219 6.1E-22 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 CNX65_RS13450 e78e57766a87bb466f95dba6227c74b2 231 SMART SM01101 1 219 4.5E-69 T 28-03-2018 IPR010179 CRISPR-associated protein Cse3 CNX65_RS13450 e78e57766a87bb466f95dba6227c74b2 231 SUPERFAMILY SSF117987 1 79 3.01E-20 T 28-03-2018 CNX65_RS01400 df632a19ac9e95db726e7c8a4b22e847 175 Gene3D G3DSA:1.10.10.60 20 60 7.5E-4 T 28-03-2018 CNX65_RS01400 df632a19ac9e95db726e7c8a4b22e847 175 Pfam PF13560 Helix-turn-helix domain 40 92 4.9E-10 T 28-03-2018 CNX65_RS01400 df632a19ac9e95db726e7c8a4b22e847 175 SUPERFAMILY SSF47413 38 92 3.75E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS01400 df632a19ac9e95db726e7c8a4b22e847 175 Gene3D G3DSA:1.10.260.40 61 159 3.9E-11 T 28-03-2018 CNX65_RS01400 df632a19ac9e95db726e7c8a4b22e847 175 SMART SM00530 44 98 5.1E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS13855 90fea97f0b2ff77fcee689ce567d9a29 255 Pfam PF00005 ABC transporter 19 167 1.2E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13855 90fea97f0b2ff77fcee689ce567d9a29 255 SUPERFAMILY SSF52540 3 225 2.19E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13855 90fea97f0b2ff77fcee689ce567d9a29 255 SMART SM00382 27 211 1.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13855 90fea97f0b2ff77fcee689ce567d9a29 255 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS13855 90fea97f0b2ff77fcee689ce567d9a29 255 Gene3D G3DSA:3.40.50.300 2 237 1.4E-56 T 28-03-2018 CNX65_RS27360 83da58a2372e8ba7bab6aab9305122e3 144 SMART SM00342 23 106 9.8E-32 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS27360 83da58a2372e8ba7bab6aab9305122e3 144 Pfam PF12833 Helix-turn-helix domain 29 108 5.3E-22 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS27360 83da58a2372e8ba7bab6aab9305122e3 144 Gene3D G3DSA:1.10.10.60 64 116 7.7E-15 T 28-03-2018 CNX65_RS27360 83da58a2372e8ba7bab6aab9305122e3 144 SUPERFAMILY SSF46689 59 110 5.82E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS27360 83da58a2372e8ba7bab6aab9305122e3 144 Gene3D G3DSA:1.10.10.60 9 63 2.2E-15 T 28-03-2018 CNX65_RS27360 83da58a2372e8ba7bab6aab9305122e3 144 SUPERFAMILY SSF46689 8 57 1.7E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS28730 f70f3b96872201c22fc61b607be2da16 419 Gene3D G3DSA:3.40.1010.10 324 414 4.6E-9 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28730 f70f3b96872201c22fc61b607be2da16 419 Pfam PF11760 Cobalamin synthesis G N-terminal 37 106 4.0E-14 T 28-03-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 CNX65_RS28730 f70f3b96872201c22fc61b607be2da16 419 SUPERFAMILY SSF53790 324 406 3.27E-9 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS28730 f70f3b96872201c22fc61b607be2da16 419 SUPERFAMILY SSF159664 186 321 9.03E-21 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CNX65_RS28730 f70f3b96872201c22fc61b607be2da16 419 SUPERFAMILY SSF159672 3 199 2.48E-24 T 28-03-2018 CNX65_RS28730 f70f3b96872201c22fc61b607be2da16 419 Gene3D G3DSA:3.30.420.180 183 323 2.9E-26 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CNX65_RS28730 f70f3b96872201c22fc61b607be2da16 419 Pfam PF01890 Cobalamin synthesis G C-terminus 193 320 7.4E-22 T 28-03-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 CNX65_RS14230 017bb03fd014f287e5d721cfdcee837f 230 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 124 2.4E-20 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CNX65_RS14230 017bb03fd014f287e5d721cfdcee837f 230 SUPERFAMILY SSF102588 1 218 2.35E-39 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS14230 017bb03fd014f287e5d721cfdcee837f 230 Gene3D G3DSA:3.40.50.10320 1 226 3.7E-41 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 Gene3D G3DSA:3.40.50.620 252 386 7.5E-24 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 SUPERFAMILY SSF47323 399 526 4.11E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 SUPERFAMILY SSF47323 554 580 4.11E-32 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 Gene3D G3DSA:3.40.50.620 2 70 2.0E-15 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 Hamap MF_00098 Methionine--tRNA ligase [metG]. 3 591 37.952 T 28-03-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 Gene3D G3DSA:1.10.730.10 387 582 3.4E-45 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 9 543 7.6E-144 T 28-03-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 Gene3D G3DSA:2.170.220.10 164 251 2.4E-17 T 28-03-2018 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 SUPERFAMILY SSF52374 7 139 8.73E-89 T 28-03-2018 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 SUPERFAMILY SSF52374 174 398 8.73E-89 T 28-03-2018 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 PRINTS PR01041 Methionyl-tRNA synthetase signature 292 307 1.1E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 1.1E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 PRINTS PR01041 Methionyl-tRNA synthetase signature 253 264 1.1E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 1.1E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 PRINTS PR01041 Methionyl-tRNA synthetase signature 7 20 1.1E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 PRINTS PR01041 Methionyl-tRNA synthetase signature 398 409 1.1E-25 T 28-03-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 Pfam PF09334 tRNA synthetases class I (M) 6 410 6.6E-142 T 28-03-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 SUPERFAMILY SSF57770 140 174 4.45E-12 T 28-03-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 CNX65_RS03170 11fb5ab43b390b8dbd46a9cb393d6dcf 596 Gene3D G3DSA:2.20.28.20 140 163 2.5E-17 T 28-03-2018 CNX65_RS16685 11d37349f08123e9cbcba6e64e3d4bef 599 SUPERFAMILY SSF52402 442 566 1.54E-31 T 28-03-2018 CNX65_RS16685 11d37349f08123e9cbcba6e64e3d4bef 599 SUPERFAMILY SSF52402 202 347 1.54E-31 T 28-03-2018 CNX65_RS16685 11d37349f08123e9cbcba6e64e3d4bef 599 Gene3D G3DSA:3.40.50.620 185 589 2.4E-38 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS16685 11d37349f08123e9cbcba6e64e3d4bef 599 Pfam PF00733 Asparagine synthase 203 586 1.4E-41 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CNX65_RS05435 87ea24110d42dcc7add79cb1d22d0ed2 512 Gene3D G3DSA:1.10.10.60 413 489 6.2E-6 T 28-03-2018 CNX65_RS05435 87ea24110d42dcc7add79cb1d22d0ed2 512 Gene3D G3DSA:3.30.450.40 107 265 5.1E-4 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS05435 87ea24110d42dcc7add79cb1d22d0ed2 512 Pfam PF13556 PucR C-terminal helix-turn-helix domain 453 511 7.8E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 Gene3D G3DSA:1.10.10.10 11 256 0.021 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 SMART SM00342 245 327 7.2E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 Pfam PF12833 Helix-turn-helix domain 251 328 2.3E-18 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 Pfam PF12625 Arabinose-binding domain of AraC transcription regulator, N-term 22 205 3.5E-47 T 28-03-2018 IPR032687 HTH-type transcriptional regulator AraC-type, N-terminal CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 Gene3D G3DSA:1.10.10.10 257 281 0.0031 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 296 311 6.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 311 327 6.6E-6 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 SUPERFAMILY SSF46689 284 329 1.65E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS27770 444583b438a101713791f67ab85e0c76 335 Gene3D G3DSA:1.10.10.60 282 332 2.7E-13 T 28-03-2018 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 PIRSF PIRSF001529 1 416 1.6E-139 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 Gene3D G3DSA:1.10.287.40 1 103 2.9E-24 T 28-03-2018 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 Gene3D G3DSA:3.30.930.10 104 413 2.4E-84 T 28-03-2018 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 413 38.964 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 PRINTS PR00981 Seryl-tRNA synthetase signature 309 322 1.3E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 PRINTS PR00981 Seryl-tRNA synthetase signature 344 360 1.3E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 PRINTS PR00981 Seryl-tRNA synthetase signature 326 342 1.3E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 PRINTS PR00981 Seryl-tRNA synthetase signature 257 269 1.3E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 PRINTS PR00981 Seryl-tRNA synthetase signature 269 282 1.3E-30 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 219 391 5.3E-25 T 28-03-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 SUPERFAMILY SSF46589 2 111 1.05E-26 T 28-03-2018 IPR010978 tRNA-binding arm GO:0000166 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 106 2.1E-26 T 28-03-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 TIGRFAM TIGR00414 serS: serine--tRNA ligase 2 408 2.3E-131 T 28-03-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 CNX65_RS00585 f47c3da91f89c056d6361180f4171ed9 416 SUPERFAMILY SSF55681 114 415 3.73E-87 T 28-03-2018 CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 SMART SM00829 15 355 9.6E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 SUPERFAMILY SSF50129 4 193 3.69E-53 T 28-03-2018 IPR011032 GroES-like CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 Pfam PF00107 Zinc-binding dehydrogenase 197 315 2.4E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 SUPERFAMILY SSF51735 159 322 1.97E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 Gene3D G3DSA:3.90.180.10 1 188 1.6E-47 T 28-03-2018 CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 153 9.1E-22 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 Gene3D G3DSA:3.40.50.720 189 301 9.4E-15 T 28-03-2018 CNX65_RS33655 0416850a4aab90e9436e8a2d3dbbb420 360 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS05850 f5e2bab4a7ea14f0719cb0184a68fa44 290 PRINTS PR00164 ABC-2 type transport system membrane protein signature 59 80 5.2E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05850 f5e2bab4a7ea14f0719cb0184a68fa44 290 PRINTS PR00164 ABC-2 type transport system membrane protein signature 211 230 5.2E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05850 f5e2bab4a7ea14f0719cb0184a68fa44 290 PRINTS PR00164 ABC-2 type transport system membrane protein signature 231 250 5.2E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05850 f5e2bab4a7ea14f0719cb0184a68fa44 290 PIRSF PIRSF006648 9 289 2.0E-25 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05850 f5e2bab4a7ea14f0719cb0184a68fa44 290 Pfam PF01061 ABC-2 type transporter 45 253 5.0E-16 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 Gene3D G3DSA:3.30.450.40 11 249 1.1E-7 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 261 275 4.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 275 291 4.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 291 303 4.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 SMART SM00421 258 315 4.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 SUPERFAMILY SSF46894 249 317 2.58E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 Gene3D G3DSA:1.10.10.10 250 319 2.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 SUPERFAMILY SSF55781 33 172 2.29E-5 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS23125 4613c5557da547d87a5c9577fe2a7350 320 Pfam PF00196 Bacterial regulatory proteins, luxR family 260 312 8.9E-10 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 149 366 1.9E-8 T 28-03-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 37 271 8.5E-54 T 28-03-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01182 Ornithine decarboxylase signature 330 340 2.1E-23 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01182 Ornithine decarboxylase signature 28 52 2.1E-23 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01182 Ornithine decarboxylase signature 54 81 2.1E-23 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01182 Ornithine decarboxylase signature 128 150 2.1E-23 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01182 Ornithine decarboxylase signature 98 122 2.1E-23 T 28-03-2018 IPR002433 Ornithine decarboxylase GO:0006596 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 Gene3D G3DSA:2.40.37.10 254 389 1.4E-26 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 SUPERFAMILY SSF51419 34 273 1.44E-67 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 261 280 3.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 178 191 3.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 56 74 3.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 76 88 3.6E-17 T 28-03-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 SUPERFAMILY SSF50621 249 388 1.44E-28 T 28-03-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 Gene3D G3DSA:3.20.20.10 38 253 7.6E-57 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS27695 6e8ea2aa8091e3673766afe233920963 389 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 56 74 - T 28-03-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site CNX65_RS15225 0d55cd56c40dd6498732ac77c3156535 1320 Gene3D G3DSA:2.20.140.10 8 76 6.9E-12 T 28-03-2018 IPR008893 WGR domain CNX65_RS15225 0d55cd56c40dd6498732ac77c3156535 1320 SUPERFAMILY SSF142921 29 72 2.75E-9 T 28-03-2018 IPR008893 WGR domain CNX65_RS15225 0d55cd56c40dd6498732ac77c3156535 1320 SMART SM00773 10 77 2.4E-12 T 28-03-2018 IPR008893 WGR domain CNX65_RS15225 0d55cd56c40dd6498732ac77c3156535 1320 Pfam PF05406 WGR domain 14 72 2.9E-15 T 28-03-2018 IPR008893 WGR domain CNX65_RS15225 0d55cd56c40dd6498732ac77c3156535 1320 Pfam PF13569 Domain of unknown function (DUF4132) 1048 1224 5.4E-45 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS14045 4a0c497b3cde9ec117ca3c8e4b3fb141 211 Gene3D G3DSA:1.10.260.40 67 91 5.2E-9 T 28-03-2018 CNX65_RS14045 4a0c497b3cde9ec117ca3c8e4b3fb141 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 41 85 4.3E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14045 4a0c497b3cde9ec117ca3c8e4b3fb141 211 Gene3D G3DSA:1.10.10.60 27 66 9.7E-13 T 28-03-2018 CNX65_RS14045 4a0c497b3cde9ec117ca3c8e4b3fb141 211 Gene3D G3DSA:1.10.357.10 92 211 7.8E-11 T 28-03-2018 CNX65_RS14045 4a0c497b3cde9ec117ca3c8e4b3fb141 211 SUPERFAMILY SSF46689 33 97 4.99E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14505 1475c51317f4f0f9587c38782e2cde94 226 Gene3D G3DSA:1.10.357.10 80 226 4.8E-27 T 28-03-2018 CNX65_RS14505 1475c51317f4f0f9587c38782e2cde94 226 Gene3D G3DSA:1.10.10.60 3 73 2.0E-12 T 28-03-2018 CNX65_RS14505 1475c51317f4f0f9587c38782e2cde94 226 SUPERFAMILY SSF48498 83 225 2.89E-20 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS14505 1475c51317f4f0f9587c38782e2cde94 226 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 88 225 2.5E-8 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CNX65_RS14505 1475c51317f4f0f9587c38782e2cde94 226 SUPERFAMILY SSF46689 12 82 1.13E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14505 1475c51317f4f0f9587c38782e2cde94 226 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 67 2.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS31685 99e7edc57a41eb7666468aa7f3115c2f 9459 Gene3D G3DSA:1.10.287.620 5325 5548 3.6E-4 T 28-03-2018 CNX65_RS31685 99e7edc57a41eb7666468aa7f3115c2f 9459 Gene3D G3DSA:1.10.287.620 679 915 0.32 T 28-03-2018 CNX65_RS31685 99e7edc57a41eb7666468aa7f3115c2f 9459 Gene3D G3DSA:1.10.287.620 1150 1262 0.21 T 28-03-2018 CNX65_RS31685 99e7edc57a41eb7666468aa7f3115c2f 9459 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 2873 2880 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS31685 99e7edc57a41eb7666468aa7f3115c2f 9459 Gene3D G3DSA:1.10.3290.10 409 674 1.2E-18 T 28-03-2018 IPR003812 Fido domain CNX65_RS31685 99e7edc57a41eb7666468aa7f3115c2f 9459 Gene3D G3DSA:1.20.1600.10 42 330 5.0E-4 T 28-03-2018 CNX65_RS31685 99e7edc57a41eb7666468aa7f3115c2f 9459 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 9336 9426 1.4E-8 T 28-03-2018 IPR028908 Tox-PL domain CNX65_RS17640 af4b8f4d6a793c7c3f6a109ddead5ab2 111 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 7 104 3.7E-6 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17640 af4b8f4d6a793c7c3f6a109ddead5ab2 111 SUPERFAMILY SSF161098 4 105 1.96E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17640 af4b8f4d6a793c7c3f6a109ddead5ab2 111 Gene3D G3DSA:1.10.3720.10 1 107 3.4E-13 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 SUPERFAMILY SSF103491 3 426 6.15E-121 T 28-03-2018 IPR023201 SecY subunit domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 435 28.875 T 28-03-2018 IPR026593 Protein translocase subunit SecY CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 ProSitePatterns PS00756 Protein secY signature 2. 173 190 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PIRSF PIRSF004557 2 436 7.6E-119 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 ProSitePatterns PS00755 Protein secY signature 1. 72 91 - T 28-03-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 Pfam PF00344 SecY translocase 72 419 5.4E-115 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 431 4.2E-132 T 28-03-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 Gene3D G3DSA:1.10.3370.10 1 436 5.4E-153 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 266 285 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 71 91 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 112 135 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 368 386 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 154 179 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 180 203 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 313 335 3.2E-103 T 28-03-2018 CNX65_RS32350 034e690015064ebbf6af7224ad0304dc 436 PRINTS PR00303 Preprotein translocase SecY subunit signature 404 422 3.2E-103 T 28-03-2018 CNX65_RS34640 20df5bea6143167b0aabf88f3200bf30 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34640 20df5bea6143167b0aabf88f3200bf30 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34640 20df5bea6143167b0aabf88f3200bf30 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 188 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34640 20df5bea6143167b0aabf88f3200bf30 302 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 190 207 1.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34640 20df5bea6143167b0aabf88f3200bf30 302 Pfam PF00106 short chain dehydrogenase 6 205 8.6E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34640 20df5bea6143167b0aabf88f3200bf30 302 Gene3D G3DSA:3.40.50.720 1 260 7.1E-37 T 28-03-2018 CNX65_RS34640 20df5bea6143167b0aabf88f3200bf30 302 SUPERFAMILY SSF51735 1 258 1.84E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18655 47691860605e70a6eaa71fa5014dd502 490 PIRSF PIRSF009414 62 489 6.8E-55 T 28-03-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 CNX65_RS18655 47691860605e70a6eaa71fa5014dd502 490 Pfam PF05893 Acyl-CoA reductase (LuxC) 75 480 7.8E-73 T 28-03-2018 IPR008670 Long-chain-fatty-acyl-CoA reductase, LuxC GO:0003995|GO:0008218|GO:0055114 KEGG: 00073+1.2.1.50|MetaCyc: PWY-7723 CNX65_RS18655 47691860605e70a6eaa71fa5014dd502 490 SUPERFAMILY SSF53720 78 353 1.07E-6 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS18655 47691860605e70a6eaa71fa5014dd502 490 Gene3D G3DSA:3.40.605.10 54 320 1.3E-12 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS07170 56d37dfd4acabbfbbb5501fc22ec9ee8 222 SMART SM00448 1 109 2.0E-31 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS07170 56d37dfd4acabbfbbb5501fc22ec9ee8 222 Pfam PF00072 Response regulator receiver domain 3 109 2.0E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS07170 56d37dfd4acabbfbbb5501fc22ec9ee8 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 220 3.2E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS07170 56d37dfd4acabbfbbb5501fc22ec9ee8 222 SMART SM00862 148 220 2.1E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS07170 56d37dfd4acabbfbbb5501fc22ec9ee8 222 Gene3D G3DSA:1.10.10.10 115 222 6.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07170 56d37dfd4acabbfbbb5501fc22ec9ee8 222 SUPERFAMILY SSF52172 2 185 3.27E-32 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS07170 56d37dfd4acabbfbbb5501fc22ec9ee8 222 Gene3D G3DSA:3.40.50.2300 1 114 1.8E-28 T 28-03-2018 CNX65_RS21200 36d169b6730e0159e933ebf8f4629a91 188 Gene3D G3DSA:1.10.357.10 70 188 7.1E-21 T 28-03-2018 CNX65_RS21200 36d169b6730e0159e933ebf8f4629a91 188 Gene3D G3DSA:1.10.10.60 2 57 1.6E-10 T 28-03-2018 CNX65_RS21200 36d169b6730e0159e933ebf8f4629a91 188 SUPERFAMILY SSF48498 76 181 8.15E-19 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS21200 36d169b6730e0159e933ebf8f4629a91 188 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 46 6.6E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21200 36d169b6730e0159e933ebf8f4629a91 188 SUPERFAMILY SSF46689 6 68 1.75E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS13795 740815a9bd2e4f1bc5d1c819826b901b 332 Gene3D G3DSA:1.10.3470.10 7 332 3.1E-61 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS13795 740815a9bd2e4f1bc5d1c819826b901b 332 Pfam PF01032 FecCD transport family 22 326 8.6E-80 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS13795 740815a9bd2e4f1bc5d1c819826b901b 332 SUPERFAMILY SSF81345 12 326 2.09E-66 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 SMART SM00829 12 328 5.7E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 SUPERFAMILY SSF51735 140 298 1.67E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 134 2.8E-23 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 Gene3D G3DSA:3.40.50.720 166 300 4.3E-18 T 28-03-2018 CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 61 75 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 SUPERFAMILY SSF50129 5 164 2.43E-40 T 28-03-2018 IPR011032 GroES-like CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 Gene3D G3DSA:3.90.180.10 1 165 4.4E-43 T 28-03-2018 CNX65_RS16860 b7e868b3809d12ed73315a5b4f97ecae 330 Pfam PF00107 Zinc-binding dehydrogenase 177 293 6.6E-13 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 SMART SM00862 153 228 8.2E-26 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 Gene3D G3DSA:3.40.50.2300 1 123 6.4E-35 T 28-03-2018 CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 SUPERFAMILY SSF46894 129 228 3.91E-29 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 228 8.6E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 SMART SM00448 7 118 7.3E-39 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 SUPERFAMILY SSF52172 5 128 3.27E-38 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 Gene3D G3DSA:1.10.10.10 124 233 1.1E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01945 7ffec0a7b5391c8635c0581f665de8b0 233 Pfam PF00072 Response regulator receiver domain 10 118 2.2E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS22315 91b82c58c18a32554bcef31543b13d97 193 Pfam PF01966 HD domain 37 135 8.6E-5 T 28-03-2018 IPR006674 HD domain CNX65_RS22315 91b82c58c18a32554bcef31543b13d97 193 Gene3D G3DSA:1.10.3210.10 21 176 3.5E-7 T 28-03-2018 CNX65_RS22315 91b82c58c18a32554bcef31543b13d97 193 SUPERFAMILY SSF109604 34 137 3.84E-7 T 28-03-2018 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 Gene3D G3DSA:3.40.50.2300 1 131 2.4E-21 T 28-03-2018 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 SUPERFAMILY SSF46894 132 196 4.76E-15 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 Pfam PF00196 Bacterial regulatory proteins, luxR family 150 196 1.6E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 SMART SM00421 148 210 1.0E-12 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 Gene3D G3DSA:1.10.10.10 132 214 3.4E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 SUPERFAMILY SSF52172 2 147 5.98E-20 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 Pfam PF00072 Response regulator receiver domain 3 107 1.1E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 165 181 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 151 165 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 181 193 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13975 76ee3e64f7a86ea73def0c257b442365 214 SMART SM00448 1 120 2.7E-10 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 Pfam PF00085 Thioredoxin 5 105 2.7E-33 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 ProSitePatterns PS00194 Thioredoxin family active site. 25 43 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 Gene3D G3DSA:3.40.30.10 2 108 1.1E-34 T 28-03-2018 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 PRINTS PR00421 Thioredoxin family signature 72 83 2.9E-8 T 28-03-2018 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 PRINTS PR00421 Thioredoxin family signature 24 32 2.9E-8 T 28-03-2018 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 PRINTS PR00421 Thioredoxin family signature 32 41 2.9E-8 T 28-03-2018 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 SUPERFAMILY SSF52833 4 108 5.74E-38 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 PIRSF PIRSF000077 2 108 1.2E-42 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CNX65_RS35005 3f610e058840406f63add06668f0e4c3 108 TIGRFAM TIGR01068 thioredoxin: thioredoxin 9 105 9.0E-39 T 28-03-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 SMART SM00448 31 143 5.5E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 SUPERFAMILY SSF46894 171 237 7.48E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 Gene3D G3DSA:1.10.10.10 153 238 1.5E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07685 4126edacec98369964c1a004649f0317 238 Pfam PF00072 Response regulator receiver domain 33 136 1.1E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 Pfam PF00196 Bacterial regulatory proteins, luxR family 177 231 2.1E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 207 219 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 191 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 207 1.8E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 SUPERFAMILY SSF52172 32 152 1.01E-24 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS07685 4126edacec98369964c1a004649f0317 238 ProSitePatterns PS00622 LuxR-type HTH domain signature. 191 218 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 Gene3D G3DSA:3.40.50.2300 30 152 9.0E-25 T 28-03-2018 CNX65_RS07685 4126edacec98369964c1a004649f0317 238 SMART SM00421 174 231 6.1E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11045 1d438ce7c1dfd1aa101fd2b6ec421c0c 295 PIRSF PIRSF000707 1 295 3.2E-81 T 28-03-2018 IPR016259 Hygromycin-B kinase KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 CNX65_RS11045 1d438ce7c1dfd1aa101fd2b6ec421c0c 295 SUPERFAMILY SSF56112 46 261 3.06E-23 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS11045 1d438ce7c1dfd1aa101fd2b6ec421c0c 295 Gene3D G3DSA:3.30.200.20 7 103 1.9E-4 T 28-03-2018 CNX65_RS11045 1d438ce7c1dfd1aa101fd2b6ec421c0c 295 Pfam PF01636 Phosphotransferase enzyme family 39 262 9.8E-21 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS11045 1d438ce7c1dfd1aa101fd2b6ec421c0c 295 Gene3D G3DSA:3.90.1200.10 106 268 3.9E-16 T 28-03-2018 CNX65_RS32470 5e30228804e8b37e54bc40b71c8adca3 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 28-03-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32470 5e30228804e8b37e54bc40b71c8adca3 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 1.9E-64 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CNX65_RS32470 5e30228804e8b37e54bc40b71c8adca3 156 SUPERFAMILY SSF47973 1 149 1.29E-57 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CNX65_RS32470 5e30228804e8b37e54bc40b71c8adca3 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.2E-59 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CNX65_RS32470 5e30228804e8b37e54bc40b71c8adca3 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 34.861 T 28-03-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 CNX65_RS32470 5e30228804e8b37e54bc40b71c8adca3 156 PIRSF PIRSF002122 5 156 2.8E-55 T 28-03-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 CNX65_RS32470 5e30228804e8b37e54bc40b71c8adca3 156 Gene3D G3DSA:1.10.455.10 6 156 5.0E-55 T 28-03-2018 IPR023798 Ribosomal protein S7 domain CNX65_RS28735 8bd5e404162784c6bb740ff35cd15d19 282 Gene3D G3DSA:3.40.50.150 102 280 7.2E-18 T 28-03-2018 CNX65_RS28735 8bd5e404162784c6bb740ff35cd15d19 282 SUPERFAMILY SSF53335 112 252 2.05E-19 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS23135 8f109e87c43ba4b7d08864a26ef9dc66 165 Gene3D G3DSA:1.10.10.10 12 155 1.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23135 8f109e87c43ba4b7d08864a26ef9dc66 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 95 111 8.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS23135 8f109e87c43ba4b7d08864a26ef9dc66 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 126 146 8.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS23135 8f109e87c43ba4b7d08864a26ef9dc66 165 PRINTS PR00598 Bacterial regulatory protein MarR family signature 76 91 8.4E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS23135 8f109e87c43ba4b7d08864a26ef9dc66 165 SUPERFAMILY SSF46785 6 150 7.58E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23135 8f109e87c43ba4b7d08864a26ef9dc66 165 SMART SM00347 33 136 1.9E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS23135 8f109e87c43ba4b7d08864a26ef9dc66 165 Pfam PF12802 MarR family 40 99 4.8E-10 T 28-03-2018 CNX65_RS27385 19353996f2482ef8b803b942407ad445 716 SMART SM00530 339 395 2.2E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS27385 19353996f2482ef8b803b942407ad445 716 Pfam PF13560 Helix-turn-helix domain 338 394 6.3E-9 T 28-03-2018 CNX65_RS27385 19353996f2482ef8b803b942407ad445 716 Gene3D G3DSA:1.10.260.40 328 407 7.5E-10 T 28-03-2018 CNX65_RS27385 19353996f2482ef8b803b942407ad445 716 Gene3D G3DSA:1.25.40.10 444 693 5.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27385 19353996f2482ef8b803b942407ad445 716 SUPERFAMILY SSF47413 337 395 1.13E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS12340 305cb00840db6dff287d80b07b7f6385 61 Pfam PF04149 Domain of unknown function (DUF397) 8 57 1.5E-17 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS02055 bc92d4f3b84468b8757a4fc8d49942c0 347 Gene3D G3DSA:3.40.50.10490 191 346 2.4E-27 T 28-03-2018 CNX65_RS02055 bc92d4f3b84468b8757a4fc8d49942c0 347 SUPERFAMILY SSF53697 9 345 1.64E-65 T 28-03-2018 CNX65_RS02055 bc92d4f3b84468b8757a4fc8d49942c0 347 Gene3D G3DSA:3.40.50.10490 7 179 1.6E-32 T 28-03-2018 CNX65_RS02055 bc92d4f3b84468b8757a4fc8d49942c0 347 Pfam PF01380 SIS domain 46 167 1.7E-12 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS02055 bc92d4f3b84468b8757a4fc8d49942c0 347 Pfam PF01380 SIS domain 207 318 3.2E-12 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS25950 b9f47ac47ce23b44ad1e7d3f8a0439ee 450 SUPERFAMILY SSF53187 48 104 2.62E-53 T 28-03-2018 CNX65_RS25950 b9f47ac47ce23b44ad1e7d3f8a0439ee 450 SUPERFAMILY SSF53187 232 448 2.62E-53 T 28-03-2018 CNX65_RS25950 b9f47ac47ce23b44ad1e7d3f8a0439ee 450 Pfam PF04389 Peptidase family M28 240 434 5.9E-37 T 28-03-2018 IPR007484 Peptidase M28 CNX65_RS25950 b9f47ac47ce23b44ad1e7d3f8a0439ee 450 Gene3D G3DSA:3.40.630.10 48 450 7.6E-51 T 28-03-2018 CNX65_RS02715 3c76f711d55300f4d4fe3beac5ad5816 147 SUPERFAMILY SSF82607 9 95 6.41E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS02715 3c76f711d55300f4d4fe3beac5ad5816 147 Pfam PF02575 YbaB/EbfC DNA-binding family 12 97 7.2E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS02715 3c76f711d55300f4d4fe3beac5ad5816 147 Gene3D G3DSA:3.30.1310.10 1 100 6.6E-19 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS23530 3c4df63767296d7c0a9fb034c8a009c2 221 PIRSF PIRSF001357 1 218 1.6E-68 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CNX65_RS23530 3c4df63767296d7c0a9fb034c8a009c2 221 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 4 207 4.6E-65 T 28-03-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CNX65_RS23530 3c4df63767296d7c0a9fb034c8a009c2 221 Gene3D G3DSA:3.20.20.70 1 217 4.4E-84 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS23530 3c4df63767296d7c0a9fb034c8a009c2 221 SUPERFAMILY SSF51569 3 213 6.59E-69 T 28-03-2018 CNX65_RS23530 3c4df63767296d7c0a9fb034c8a009c2 221 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 2 215 31.817 T 28-03-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 CNX65_RS23530 3c4df63767296d7c0a9fb034c8a009c2 221 SMART SM01133 3 213 3.2E-79 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CNX65_RS23530 3c4df63767296d7c0a9fb034c8a009c2 221 Pfam PF01791 DeoC/LacD family aldolase 9 206 2.1E-13 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CNX65_RS21510 1ec0655be6c1d35450a5c9a20491c44b 347 Gene3D G3DSA:1.10.3470.10 18 347 2.1E-64 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS21510 1ec0655be6c1d35450a5c9a20491c44b 347 SUPERFAMILY SSF81345 19 341 6.15E-79 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS21510 1ec0655be6c1d35450a5c9a20491c44b 347 Pfam PF01032 FecCD transport family 33 341 1.2E-84 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS09340 1fbce1c8402a3923185664f856bc8e9c 109 Gene3D G3DSA:3.30.70.100 1 103 7.8E-23 T 28-03-2018 CNX65_RS09340 1fbce1c8402a3923185664f856bc8e9c 109 SUPERFAMILY SSF54909 1 94 6.6E-26 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS09340 1fbce1c8402a3923185664f856bc8e9c 109 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 76 9.9E-17 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CNX65_RS24510 f7a7a3761ea29c508439ffba029e85a3 694 Pfam PF03176 MMPL family 454 675 2.4E-52 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS24510 f7a7a3761ea29c508439ffba029e85a3 694 Pfam PF03176 MMPL family 114 363 3.5E-58 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS24510 f7a7a3761ea29c508439ffba029e85a3 694 Gene3D G3DSA:1.20.1640.10 452 670 2.1E-31 T 28-03-2018 CNX65_RS24510 f7a7a3761ea29c508439ffba029e85a3 694 Gene3D G3DSA:1.20.1640.10 113 330 5.5E-35 T 28-03-2018 CNX65_RS24510 f7a7a3761ea29c508439ffba029e85a3 694 SUPERFAMILY SSF82866 138 334 2.22E-34 T 28-03-2018 CNX65_RS24510 f7a7a3761ea29c508439ffba029e85a3 694 SUPERFAMILY SSF82866 453 673 9.42E-31 T 28-03-2018 CNX65_RS29770 27863ebae402c26cfb1d9670f05d45a1 256 SUPERFAMILY SSF55729 22 227 5.53E-43 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS29770 27863ebae402c26cfb1d9670f05d45a1 256 Pfam PF13444 Acetyltransferase (GNAT) domain 37 138 1.3E-34 T 28-03-2018 CNX65_RS29770 27863ebae402c26cfb1d9670f05d45a1 256 Gene3D G3DSA:3.40.630.30 21 166 3.3E-37 T 28-03-2018 CNX65_RS28835 dc4fae5f02071db8af6806ff2fc8db22 175 Pfam PF01161 Phosphatidylethanolamine-binding protein 36 173 1.4E-36 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CNX65_RS28835 dc4fae5f02071db8af6806ff2fc8db22 175 Gene3D G3DSA:3.90.280.10 7 175 6.7E-49 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CNX65_RS28835 dc4fae5f02071db8af6806ff2fc8db22 175 SUPERFAMILY SSF49777 7 167 2.49E-50 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CNX65_RS28835 dc4fae5f02071db8af6806ff2fc8db22 175 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 40 173 9.7E-41 T 28-03-2018 IPR005247 YbhB/YbcL CNX65_RS20060 f1fc857af473fd28898123f90cb8877c 380 Pfam PF06187 Protein of unknown function (DUF993) 16 378 3.3E-169 T 28-03-2018 IPR009334 Protein of unknown function DUF993 CNX65_RS20060 f1fc857af473fd28898123f90cb8877c 380 SUPERFAMILY SSF51569 54 326 1.15E-15 T 28-03-2018 CNX65_RS20060 f1fc857af473fd28898123f90cb8877c 380 Gene3D G3DSA:3.20.20.70 46 334 4.8E-63 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS17395 aa8e29c8f4b7683f9ac819da31a64fe3 457 ProSitePatterns PS00571 Amidases signature. 153 184 - T 28-03-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 CNX65_RS17395 aa8e29c8f4b7683f9ac819da31a64fe3 457 SUPERFAMILY SSF75304 3 446 1.57E-108 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS17395 aa8e29c8f4b7683f9ac819da31a64fe3 457 Pfam PF01425 Amidase 28 437 1.2E-90 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS17395 aa8e29c8f4b7683f9ac819da31a64fe3 457 Gene3D G3DSA:3.90.1300.10 3 457 7.0E-115 T 28-03-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 CNX65_RS02495 5e14c052a29010b71c3e20532d6e4ce3 455 Pfam PF05977 Transmembrane secretion effector 28 423 2.7E-55 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS02495 5e14c052a29010b71c3e20532d6e4ce3 455 Gene3D G3DSA:1.20.1250.20 233 428 1.9E-21 T 28-03-2018 CNX65_RS02495 5e14c052a29010b71c3e20532d6e4ce3 455 Gene3D G3DSA:1.20.1250.20 27 226 6.3E-20 T 28-03-2018 CNX65_RS02495 5e14c052a29010b71c3e20532d6e4ce3 455 SUPERFAMILY SSF103473 36 429 1.57E-52 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS07325 beac909b0328783ef0c9cce0bd708188 322 SMART SM00382 29 212 2.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS07325 beac909b0328783ef0c9cce0bd708188 322 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 12 309 3.2E-103 T 28-03-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 CNX65_RS07325 beac909b0328783ef0c9cce0bd708188 322 Pfam PF00005 ABC transporter 20 163 2.4E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS07325 beac909b0328783ef0c9cce0bd708188 322 Gene3D G3DSA:3.40.50.300 1 261 5.9E-65 T 28-03-2018 CNX65_RS07325 beac909b0328783ef0c9cce0bd708188 322 SUPERFAMILY SSF52540 4 226 7.99E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07325 beac909b0328783ef0c9cce0bd708188 322 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 SUPERFAMILY SSF51011 368 452 2.3E-15 T 28-03-2018 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 ProSitePatterns PS00512 Alpha-galactosidase signature. 139 155 - T 28-03-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 Gene3D G3DSA:2.80.10.50 553 590 3.5E-10 T 28-03-2018 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 SMART SM00458 460 590 6.1E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 Gene3D G3DSA:2.80.10.50 461 552 1.3E-24 T 28-03-2018 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 Gene3D G3DSA:3.20.20.70 96 365 5.7E-105 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 Pfam PF00652 Ricin-type beta-trefoil lectin domain 463 587 6.6E-25 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 Gene3D G3DSA:2.60.40.1180 368 455 2.4E-18 T 28-03-2018 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 SUPERFAMILY SSF51445 94 367 9.48E-103 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 SUPERFAMILY SSF50370 458 588 2.29E-35 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 PRINTS PR00740 Glycosyl hydrolase family 27 signature 134 149 6.0E-62 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 PRINTS PR00740 Glycosyl hydrolase family 27 signature 236 254 6.0E-62 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 PRINTS PR00740 Glycosyl hydrolase family 27 signature 98 117 6.0E-62 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 PRINTS PR00740 Glycosyl hydrolase family 27 signature 301 320 6.0E-62 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 PRINTS PR00740 Glycosyl hydrolase family 27 signature 209 226 6.0E-62 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 PRINTS PR00740 Glycosyl hydrolase family 27 signature 322 343 6.0E-62 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 PRINTS PR00740 Glycosyl hydrolase family 27 signature 175 196 6.0E-62 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS08310 c8bc49808d2013dae8835f9f35a74cb7 590 Pfam PF16499 Alpha galactosidase A 104 366 9.7E-86 T 28-03-2018 IPR002241 Glycoside hydrolase, family 27 GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 SUPERFAMILY SSF55120 11 226 5.44E-72 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 12 223 2.0E-69 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 10 295 17.75 T 28-03-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 Gene3D G3DSA:2.30.130.10 233 295 4.0E-19 T 28-03-2018 IPR002478 PUA domain GO:0003723 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 185 226 2.1E-12 T 28-03-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 Gene3D G3DSA:3.30.2350.10 9 230 2.3E-81 T 28-03-2018 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 Pfam PF09142 tRNA Pseudouridine synthase II, C terminal 241 295 2.6E-18 T 28-03-2018 IPR015225 tRNA pseudouridine synthase II, TruB, subfamily 2, C-terminal GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 SUPERFAMILY SSF88697 241 297 1.64E-12 T 28-03-2018 IPR015947 PUA-like domain CNX65_RS28585 be08bd1589c96144e8f263be519b6113 299 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 32 184 2.7E-51 T 28-03-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 CNX65_RS08950 3a4df5f17c3358c4e2ec20a3b57f029b 50 Gene3D G3DSA:2.160.20.50 1 49 3.7E-4 T 28-03-2018 CNX65_RS08950 3a4df5f17c3358c4e2ec20a3b57f029b 50 Pfam PF01391 Collagen triple helix repeat (20 copies) 2 44 3.8E-7 T 28-03-2018 IPR008160 Collagen triple helix repeat CNX65_RS20785 899f68de49072b06ec4b4a4ca38ab466 326 Gene3D G3DSA:3.40.50.1110 50 324 1.3E-28 T 28-03-2018 CNX65_RS20785 899f68de49072b06ec4b4a4ca38ab466 326 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 70 314 7.2E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS20785 899f68de49072b06ec4b4a4ca38ab466 326 SUPERFAMILY SSF52266 67 323 1.12E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS20020 89ed19620e0b7a562a920db2dc8bbbf4 371 SMART SM00387 277 367 2.6E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20020 89ed19620e0b7a562a920db2dc8bbbf4 371 Gene3D G3DSA:3.30.565.10 244 369 1.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20020 89ed19620e0b7a562a920db2dc8bbbf4 371 SUPERFAMILY SSF55874 262 364 3.54E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20020 89ed19620e0b7a562a920db2dc8bbbf4 371 Pfam PF07730 Histidine kinase 176 236 3.6E-11 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS11820 aacb5beebb99b1d5bd2f96ded9be7402 144 SUPERFAMILY SSF50341 2 136 5.62E-32 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11820 aacb5beebb99b1d5bd2f96ded9be7402 144 Gene3D G3DSA:2.40.50.180 22 87 1.2E-18 T 28-03-2018 CNX65_RS11820 aacb5beebb99b1d5bd2f96ded9be7402 144 SMART SM00260 1 138 7.1E-29 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11820 aacb5beebb99b1d5bd2f96ded9be7402 144 Pfam PF01584 CheW-like domain 5 139 8.5E-28 T 28-03-2018 IPR002545 CheW-like domain GO:0004871|GO:0006935|GO:0007165 CNX65_RS11820 aacb5beebb99b1d5bd2f96ded9be7402 144 Gene3D G3DSA:2.30.30.40 88 132 4.0E-7 T 28-03-2018 CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 Gene3D G3DSA:3.30.465.10 66 176 3.5E-27 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 Gene3D G3DSA:3.40.462.10 177 392 1.0E-47 T 28-03-2018 IPR016170 Vanillyl-alcohol oxidase/Cytokinin dehydrogenase C-terminal domain CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 PIRSF PIRSF000136 1 425 3.8E-103 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 Gene3D G3DSA:3.30.43.10 2 64 9.0E-14 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 Pfam PF04030 D-arabinono-1,4-lactone oxidase 170 423 1.0E-71 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 TIGRFAM TIGR01679 bact_FAD_ox: FAD-linked oxidoreductase 5 425 4.2E-108 T 28-03-2018 CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 Pfam PF01565 FAD binding domain 18 145 3.9E-23 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS00160 9a50a1cb71b40e2cdd0945deb1aca849 425 SUPERFAMILY SSF56176 4 175 3.46E-41 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 241 379 8.5E-66 T 28-03-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 1 391 54.401 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 Gene3D G3DSA:3.30.300.10 267 393 9.1E-46 T 28-03-2018 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 SUPERFAMILY SSF55973 241 390 1.69E-65 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 SUPERFAMILY SSF55973 116 240 3.92E-45 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 Pfam PF02772 S-adenosylmethionine synthetase, central domain 120 239 7.1E-43 T 28-03-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 267 275 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 122 132 - T 28-03-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 PIRSF PIRSF000497 1 392 3.0E-162 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 1 97 4.4E-41 T 28-03-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 Gene3D G3DSA:3.30.300.10 7 143 8.8E-45 T 28-03-2018 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 Gene3D G3DSA:3.30.300.10 151 266 2.1E-41 T 28-03-2018 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 SUPERFAMILY SSF55973 1 105 1.41E-44 T 28-03-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS26055 487c6b95c4c9bf0625cc399456122242 393 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 1 390 1.5E-165 T 28-03-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 CNX65_RS05460 0f8090ac907bb3642002a088775f5a23 471 Gene3D G3DSA:1.10.10.10 279 393 2.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05460 0f8090ac907bb3642002a088775f5a23 471 SMART SM00862 303 367 0.0017 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS05460 0f8090ac907bb3642002a088775f5a23 471 Pfam PF01590 GAF domain 83 199 1.5E-6 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS08140 bbc578f32fcc7e791c6fe2da4fd7e4fd 219 Pfam PF04892 VanZ like family 87 202 7.0E-19 T 28-03-2018 IPR006976 VanZ-like CNX65_RS19875 a6a5e3cea0b0332152ce47569edd9472 499 Pfam PF13360 PQQ-like domain 215 335 2.0E-7 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CNX65_RS19875 a6a5e3cea0b0332152ce47569edd9472 499 SMART SM00564 166 198 0.15 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CNX65_RS19875 a6a5e3cea0b0332152ce47569edd9472 499 SMART SM00564 256 287 63.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CNX65_RS19875 a6a5e3cea0b0332152ce47569edd9472 499 SMART SM00564 304 333 470.0 T 28-03-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat CNX65_RS19875 a6a5e3cea0b0332152ce47569edd9472 499 Gene3D G3DSA:2.140.10.10 245 493 6.0E-9 T 28-03-2018 CNX65_RS19875 a6a5e3cea0b0332152ce47569edd9472 499 Gene3D G3DSA:2.140.10.10 80 244 2.2E-7 T 28-03-2018 CNX65_RS19875 a6a5e3cea0b0332152ce47569edd9472 499 SUPERFAMILY SSF50998 150 393 3.14E-15 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS18400 541a0f0df4018c85685635c1ece93c8e 601 Pfam PF00664 ABC transporter transmembrane region 50 304 1.8E-14 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18400 541a0f0df4018c85685635c1ece93c8e 601 Gene3D G3DSA:3.40.50.300 365 599 3.1E-55 T 28-03-2018 CNX65_RS18400 541a0f0df4018c85685635c1ece93c8e 601 SUPERFAMILY SSF52540 365 595 1.02E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18400 541a0f0df4018c85685635c1ece93c8e 601 SMART SM00382 392 574 2.2E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18400 541a0f0df4018c85685635c1ece93c8e 601 Gene3D G3DSA:1.20.1560.10 15 337 5.6E-29 T 28-03-2018 CNX65_RS18400 541a0f0df4018c85685635c1ece93c8e 601 Pfam PF00005 ABC transporter 384 527 5.1E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18400 541a0f0df4018c85685635c1ece93c8e 601 SUPERFAMILY SSF90123 27 337 4.05E-35 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS06105 51cff5adebd70a1ddd93e81ea28089f0 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 252 1.7E-44 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS06105 51cff5adebd70a1ddd93e81ea28089f0 255 Gene3D G3DSA:3.90.226.10 1 255 1.3E-68 T 28-03-2018 CNX65_RS06105 51cff5adebd70a1ddd93e81ea28089f0 255 SUPERFAMILY SSF52096 5 253 5.15E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 190 218 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 Gene3D G3DSA:3.40.50.720 3 296 7.7E-78 T 28-03-2018 CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 62 293 6.4E-63 T 28-03-2018 CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 54 71 2.0E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 193 2.0E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 224 241 2.0E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 258 278 2.0E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 141 2.0E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 203 222 2.0E-37 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 183 191 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 203 222 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 141 3.2E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19960 253bb3e8bea587959c36e5c61e0c1e8b 297 SUPERFAMILY SSF51735 51 293 5.32E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02500 f0e588ab8f0618a4923566a69c40672a 423 Pfam PF05977 Transmembrane secretion effector 13 412 1.6E-52 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS02500 f0e588ab8f0618a4923566a69c40672a 423 Gene3D G3DSA:1.20.1250.20 12 208 1.0E-14 T 28-03-2018 CNX65_RS02500 f0e588ab8f0618a4923566a69c40672a 423 SUPERFAMILY SSF103473 21 405 7.59E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS02500 f0e588ab8f0618a4923566a69c40672a 423 Gene3D G3DSA:1.20.1250.20 222 419 1.5E-14 T 28-03-2018 CNX65_RS33535 dff95594dad6110c61144d51f64beaa2 275 SMART SM00062 38 262 1.9E-55 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS33535 dff95594dad6110c61144d51f64beaa2 275 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 260 4.4E-47 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS33535 dff95594dad6110c61144d51f64beaa2 275 Gene3D G3DSA:3.40.190.10 28 141 1.4E-23 T 28-03-2018 CNX65_RS33535 dff95594dad6110c61144d51f64beaa2 275 SUPERFAMILY SSF53850 5 258 5.44E-51 T 28-03-2018 CNX65_RS33535 dff95594dad6110c61144d51f64beaa2 275 Gene3D G3DSA:3.40.190.10 142 224 2.0E-21 T 28-03-2018 CNX65_RS05345 3d992aa26edd521fa0499a7460372b14 511 PIRSF PIRSF026631 27 503 1.1E-73 T 28-03-2018 IPR014529 Uncharacterised conserved protein UCP026631 CNX65_RS05345 3d992aa26edd521fa0499a7460372b14 511 Pfam PF03703 Bacterial PH domain 421 493 1.2E-10 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CNX65_RS05345 3d992aa26edd521fa0499a7460372b14 511 Pfam PF03703 Bacterial PH domain 85 144 4.8E-12 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CNX65_RS23670 5696885771faa8873cf6db58382fcf5d 190 Pfam PF09346 SMI1 / KNR4 family (SUKH-1) 46 98 5.1E-7 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CNX65_RS23670 5696885771faa8873cf6db58382fcf5d 190 SMART SM00860 46 181 2.4E-8 T 28-03-2018 IPR018958 Knr4/Smi1-like domain CNX65_RS23670 5696885771faa8873cf6db58382fcf5d 190 Gene3D G3DSA:3.40.1580.10 36 189 4.9E-18 T 28-03-2018 CNX65_RS23670 5696885771faa8873cf6db58382fcf5d 190 SUPERFAMILY SSF160631 42 161 1.7E-11 T 28-03-2018 CNX65_RS14660 bcbe80b57cd63e3606cb90743ec5c4db 501 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 50 228 2.1E-15 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS14660 bcbe80b57cd63e3606cb90743ec5c4db 501 Gene3D G3DSA:3.40.190.10 164 240 1.5E-6 T 28-03-2018 CNX65_RS14660 bcbe80b57cd63e3606cb90743ec5c4db 501 Gene3D G3DSA:3.90.76.10 39 163 1.7E-19 T 28-03-2018 CNX65_RS14660 bcbe80b57cd63e3606cb90743ec5c4db 501 Gene3D G3DSA:3.40.190.10 241 292 0.31 T 28-03-2018 CNX65_RS14660 bcbe80b57cd63e3606cb90743ec5c4db 501 SUPERFAMILY SSF53850 21 459 8.87E-44 T 28-03-2018 CNX65_RS14660 bcbe80b57cd63e3606cb90743ec5c4db 501 Gene3D G3DSA:3.10.105.10 298 456 8.9E-18 T 28-03-2018 CNX65_RS09635 c1c86b2c671bfb0b0e012ecc00fd2859 284 Gene3D G3DSA:1.10.3720.10 2 272 2.4E-34 T 28-03-2018 CNX65_RS09635 c1c86b2c671bfb0b0e012ecc00fd2859 284 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 272 4.7E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09635 c1c86b2c671bfb0b0e012ecc00fd2859 284 SUPERFAMILY SSF161098 14 284 1.53E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PIRSF PIRSF019574 24 383 3.7E-102 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 86 107 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 113 127 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 283 302 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 203 222 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 160 176 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 70 86 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 328 354 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 129 142 3.8E-44 T 28-03-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 SUPERFAMILY SSF53850 64 383 5.43E-80 T 28-03-2018 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 Gene3D G3DSA:3.40.190.10 182 335 7.5E-26 T 28-03-2018 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 Pfam PF13416 Bacterial extracellular solute-binding protein 84 337 5.8E-36 T 28-03-2018 CNX65_RS28935 be15d6db7488ffc340dcb25b97bc2123 383 Gene3D G3DSA:3.40.190.10 39 181 1.4E-19 T 28-03-2018 CNX65_RS00800 2f5f52dddc4f36d96cfeded7a92243f0 279 Gene3D G3DSA:3.40.50.720 4 36 3.4E-6 T 28-03-2018 CNX65_RS00800 2f5f52dddc4f36d96cfeded7a92243f0 279 Gene3D G3DSA:3.90.25.10 155 276 8.8E-23 T 28-03-2018 CNX65_RS00800 2f5f52dddc4f36d96cfeded7a92243f0 279 Gene3D G3DSA:3.40.50.720 37 154 2.5E-20 T 28-03-2018 CNX65_RS00800 2f5f52dddc4f36d96cfeded7a92243f0 279 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 207 8.6E-35 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS00800 2f5f52dddc4f36d96cfeded7a92243f0 279 SUPERFAMILY SSF51735 1 270 1.81E-64 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02570 5624f8d01bfcd18d69132df807d3aec1 220 Pfam PF01730 UreF 33 170 4.6E-17 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CNX65_RS02570 5624f8d01bfcd18d69132df807d3aec1 220 PIRSF PIRSF009467 1 220 1.8E-35 T 28-03-2018 IPR002639 Urease accessory protein UreF GO:0006807|GO:0016151 CNX65_RS13245 0e72bf9aa700ebb2e4bb33441e315689 180 SMART SM00347 34 137 2.3E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS13245 0e72bf9aa700ebb2e4bb33441e315689 180 SUPERFAMILY SSF46785 3 151 1.18E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13245 0e72bf9aa700ebb2e4bb33441e315689 180 Pfam PF12802 MarR family 45 99 1.2E-10 T 28-03-2018 CNX65_RS13245 0e72bf9aa700ebb2e4bb33441e315689 180 Gene3D G3DSA:1.10.10.10 6 154 8.5E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Pfam PF13549 ATP-grasp domain 629 834 5.8E-57 T 28-03-2018 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Gene3D G3DSA:3.40.50.261 289 450 2.5E-37 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Gene3D G3DSA:3.40.50.720 171 288 3.1E-39 T 28-03-2018 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 SMART SM00881 171 266 9.9E-35 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 SUPERFAMILY SSF52210 453 599 1.01E-28 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 SUPERFAMILY SSF52210 291 447 1.31E-35 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Gene3D G3DSA:3.40.630.30 8 161 8.0E-19 T 28-03-2018 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Pfam PF00583 Acetyltransferase (GNAT) family 44 128 1.0E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 SUPERFAMILY SSF56059 637 835 1.26E-30 T 28-03-2018 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 SUPERFAMILY SSF55729 19 134 1.92E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Pfam PF13380 CoA binding domain 176 291 1.2E-24 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Gene3D G3DSA:3.40.50.261 451 604 3.0E-30 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 311 447 3.1E-46 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 SUPERFAMILY SSF51735 162 293 1.82E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Gene3D G3DSA:3.30.470.20 712 837 3.4E-35 T 28-03-2018 CNX65_RS09550 4905d4fbc2f7e0fbfea421127408c24e 852 Gene3D G3DSA:3.30.1490.20 653 711 5.5E-18 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 Pfam PF13537 Glutamine amidotransferase domain 51 172 1.1E-45 T 28-03-2018 IPR017932 Glutamine amidotransferase type 2 domain CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 PIRSF PIRSF001589 1 609 2.5E-138 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 SUPERFAMILY SSF52402 454 578 5.98E-64 T 28-03-2018 CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 SUPERFAMILY SSF52402 223 394 5.98E-64 T 28-03-2018 CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 Gene3D G3DSA:3.40.50.620 225 602 2.1E-58 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 Gene3D G3DSA:3.60.20.10 1 224 3.0E-54 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 Pfam PF00733 Asparagine synthase 243 587 5.0E-83 T 28-03-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 SUPERFAMILY SSF56235 1 227 4.55E-64 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS15600 bbcfd1bb714125f67a4f7b01bf09bb4b 612 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 537 7.8E-141 T 28-03-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 CNX65_RS25775 d0b43b2ddb428ab674e96b64fd7d5a98 212 SUPERFAMILY SSF109604 10 129 1.4E-18 T 28-03-2018 CNX65_RS25775 d0b43b2ddb428ab674e96b64fd7d5a98 212 Gene3D G3DSA:1.10.472.50 6 105 4.5E-9 T 28-03-2018 CNX65_RS30150 2ac4933eea34120569b13fca534dea5b 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 2.8E-46 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS30150 2ac4933eea34120569b13fca534dea5b 255 Gene3D G3DSA:1.10.12.10 217 254 2.8E-10 T 28-03-2018 IPR014748 Crontonase, C-terminal CNX65_RS30150 2ac4933eea34120569b13fca534dea5b 255 Gene3D G3DSA:3.90.226.10 1 216 8.8E-52 T 28-03-2018 CNX65_RS30150 2ac4933eea34120569b13fca534dea5b 255 SUPERFAMILY SSF52096 2 253 1.49E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS09230 812b25c445e54ebe8f2ce6151392b075 372 Pfam PF02558 Ketopantoate reductase PanE/ApbA 31 107 2.8E-7 T 28-03-2018 IPR013332 Ketopantoate reductase, N-terminal domain GO:0008677|GO:0055114 KEGG: 00052+1.1.1.16|KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654|MetaCyc: PWY-7862 CNX65_RS09230 812b25c445e54ebe8f2ce6151392b075 372 Gene3D G3DSA:3.40.50.720 28 228 3.3E-10 T 28-03-2018 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 28-03-2018 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 Gene3D G3DSA:1.10.260.40 3 57 2.4E-21 T 28-03-2018 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.7E-16 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 Pfam PF13377 Periplasmic binding protein-like domain 166 328 8.3E-39 T 28-03-2018 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 6.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 6.1E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 SUPERFAMILY SSF47413 3 60 8.16E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 SUPERFAMILY SSF53822 63 329 3.87E-66 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 SMART SM00354 2 72 3.0E-23 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 Gene3D G3DSA:3.40.50.2300 58 170 3.1E-28 T 28-03-2018 CNX65_RS09345 6dabcd8ab13e00f2a426af00f45c88dd 333 Gene3D G3DSA:3.40.50.2300 171 316 1.7E-45 T 28-03-2018 CNX65_RS21290 44d05e9551b6a6069a1705175040a06f 461 Pfam PF13203 Putative metallopeptidase domain 45 128 3.2E-6 T 28-03-2018 IPR025154 Putative metallopeptidase domain CNX65_RS21290 44d05e9551b6a6069a1705175040a06f 461 Gene3D G3DSA:3.40.50.410 309 453 6.0E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS21290 44d05e9551b6a6069a1705175040a06f 461 SUPERFAMILY SSF53300 322 419 3.34E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 147 176 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Gene3D G3DSA:3.90.1170.30 2 45 4.8E-20 T 28-03-2018 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Gene3D G3DSA:3.90.1170.30 46 166 1.3E-39 T 28-03-2018 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 SUPERFAMILY SSF51230 1 96 4.32E-28 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Gene3D G3DSA:3.30.559.10 312 563 1.6E-73 T 28-03-2018 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Gene3D G3DSA:4.10.320.10 260 309 5.9E-20 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Pfam PF00364 Biotin-requiring enzyme 124 196 5.2E-21 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Pfam PF00364 Biotin-requiring enzyme 5 76 4.3E-22 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Pfam PF02817 e3 binding domain 263 297 2.7E-14 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 TIGRFAM TIGR02927 SucB_Actino: 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase 1 570 2.2E-261 T 28-03-2018 IPR014276 2-oxoglutarate dehydrogenase, E2 component KEGG: 00010+2.3.1.12|KEGG: 00020+2.3.1.12|KEGG: 00620+2.3.1.12 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 333 561 1.7E-69 T 28-03-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 SUPERFAMILY SSF52777 321 561 2.58E-73 T 28-03-2018 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 28-03-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 SUPERFAMILY SSF51230 123 215 2.49E-26 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 Gene3D G3DSA:3.90.1170.30 167 259 0.0033 T 28-03-2018 CNX65_RS06675 8dcc29c9604b6e458108eb68a8427fa0 570 SUPERFAMILY SSF47005 257 301 7.19E-12 T 28-03-2018 IPR004167 E3-binding domain GO:0008152|GO:0016746 Reactome: R-HSA-389661 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 Gene3D G3DSA:3.30.300.50 43 120 5.8E-25 T 28-03-2018 IPR035070 Streptogrisin prodomain CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 Gene3D G3DSA:3.30.300.50 121 189 6.9E-14 T 28-03-2018 IPR035070 Streptogrisin prodomain CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 PIRSF PIRSF001134 1 368 7.4E-88 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 Gene3D G3DSA:2.40.10.10 271 352 1.1E-9 T 28-03-2018 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 ProSitePatterns PS00134 Serine proteases, trypsin family, histidine active site. 217 222 - T 28-03-2018 IPR018114 Serine proteases, trypsin family, histidine active site GO:0004252|GO:0006508 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 Gene3D G3DSA:2.40.10.10 193 270 2.4E-15 T 28-03-2018 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 SUPERFAMILY SSF50494 195 361 1.7E-21 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 Pfam PF02983 Alpha-lytic protease prodomain 124 175 6.5E-14 T 28-03-2018 IPR004236 Peptidase S1A, alpha-lytic prodomain GO:0005576|GO:0006508|GO:0008236 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 215 229 3.0E-24 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 292 309 3.0E-24 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 336 350 3.0E-24 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 271 291 3.0E-24 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS21520 3b0262374433d278a5207b6ca6987954 368 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 311 334 3.0E-24 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 Gene3D G3DSA:1.10.240.10 208 312 4.4E-19 T 28-03-2018 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 SUPERFAMILY SSF52374 3 320 1.07E-65 T 28-03-2018 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 4 318 2.0E-70 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 60 79 1.4E-12 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 189 199 1.4E-12 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 13 29 1.4E-12 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 136 157 1.4E-12 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 Gene3D G3DSA:3.40.50.620 1 207 4.7E-50 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS03735 3d1158b11abe53e4b133090396db137d 331 Pfam PF00579 tRNA synthetases class I (W and Y) 5 275 8.0E-51 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS21315 210021af65afa3ba3198cc5edd9aff77 136 Pfam PF13474 SnoaL-like domain 51 133 1.1E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS21315 210021af65afa3ba3198cc5edd9aff77 136 Gene3D G3DSA:3.10.450.50 2 135 8.8E-12 T 28-03-2018 CNX65_RS21315 210021af65afa3ba3198cc5edd9aff77 136 SUPERFAMILY SSF54427 42 132 2.6E-13 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 Pfam PF01494 FAD binding domain 271 307 7.6E-8 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 Pfam PF01494 FAD binding domain 3 155 2.6E-12 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 Gene3D G3DSA:3.50.50.60 1 310 2.3E-34 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 SUPERFAMILY SSF51905 2 158 5.83E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 SUPERFAMILY SSF51905 261 357 5.83E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 305 1.1E-18 T 28-03-2018 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 274 289 1.1E-18 T 28-03-2018 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 137 152 1.1E-18 T 28-03-2018 CNX65_RS24505 af23c3af48024768be30e17e7dd3731f 384 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 1.1E-18 T 28-03-2018 CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 SUPERFAMILY SSF52540 344 528 4.21E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 SUPERFAMILY SSF52540 16 234 1.42E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 Pfam PF00005 ABC transporter 347 475 6.0E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 Pfam PF00005 ABC transporter 21 191 6.7E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 SMART SM00382 29 235 3.1E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 SMART SM00382 352 528 6.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 Gene3D G3DSA:3.40.50.300 3 299 4.8E-39 T 28-03-2018 CNX65_RS07850 d2c9a9118ee4acc32d749446208f1229 539 Gene3D G3DSA:3.40.50.300 326 539 3.1E-33 T 28-03-2018 CNX65_RS09950 4b623fb0e8f8a4583d6cad6163740a71 137 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 16 131 6.0E-34 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 42 61 3.4E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 42 3.4E-5 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 SMART SM00345 13 71 8.6E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 SMART SM00895 81 204 5.2E-20 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 Gene3D G3DSA:1.10.10.10 2 67 1.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 Gene3D G3DSA:1.20.120.530 68 219 5.3E-32 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 9.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 9.3E-7 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 SUPERFAMILY SSF48008 82 209 1.44E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 SUPERFAMILY SSF46785 8 75 9.0E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 Pfam PF07729 FCD domain 82 204 1.2E-23 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS07785 ceb4a5e5ef856214a4acfb34de5a90a1 219 Pfam PF00392 Bacterial regulatory proteins, gntR family 11 71 4.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS20280 5e344f47ab65fa2cde8abb6184c8f920 385 SUPERFAMILY SSF55874 260 379 3.01E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20280 5e344f47ab65fa2cde8abb6184c8f920 385 Gene3D G3DSA:3.30.565.10 255 381 5.0E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS20280 5e344f47ab65fa2cde8abb6184c8f920 385 Pfam PF07730 Histidine kinase 174 237 9.5E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS19090 6a50083f8c6bb5b7b58390a928ce72d7 223 SUPERFAMILY SSF46689 14 75 4.72E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS19090 6a50083f8c6bb5b7b58390a928ce72d7 223 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 80 191 2.4E-10 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CNX65_RS19090 6a50083f8c6bb5b7b58390a928ce72d7 223 SUPERFAMILY SSF48498 82 218 2.33E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS19090 6a50083f8c6bb5b7b58390a928ce72d7 223 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 64 4.3E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19090 6a50083f8c6bb5b7b58390a928ce72d7 223 Gene3D G3DSA:1.10.357.10 1 223 2.2E-39 T 28-03-2018 CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 3.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 3.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 3.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 3.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.7E-26 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 Gene3D G3DSA:3.40.50.720 4 274 2.4E-64 T 28-03-2018 CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 SUPERFAMILY SSF51735 5 240 1.36E-63 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 Pfam PF00106 short chain dehydrogenase 8 189 4.1E-53 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.7E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS01890 bbacb1f961cc4666b0152ba3811836db 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 172 0.004 T 28-03-2018 CNX65_RS29025 f0e0139840f027e6bf8825a8ca9bf9b5 585 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 276 498 4.2E-64 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CNX65_RS29025 f0e0139840f027e6bf8825a8ca9bf9b5 585 SUPERFAMILY SSF102405 309 499 2.44E-33 T 28-03-2018 CNX65_RS29025 f0e0139840f027e6bf8825a8ca9bf9b5 585 Gene3D G3DSA:3.40.50.450 325 472 1.1E-35 T 28-03-2018 CNX65_RS29025 f0e0139840f027e6bf8825a8ca9bf9b5 585 Pfam PF02481 DNA recombination-mediator protein A 277 492 4.1E-67 T 28-03-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 Gene3D G3DSA:3.20.20.80 15 466 3.6E-160 T 28-03-2018 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 369 377 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 SUPERFAMILY SSF51445 16 462 2.71E-153 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 21 35 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 299 313 8.4E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 369 377 8.4E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 411 428 8.4E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 435 447 8.4E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 PRINTS PR00131 Glycosyl hydrolase family 1 signature 390 401 8.4E-20 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 Pfam PF00232 Glycosyl hydrolase family 1 16 463 8.9E-156 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08395 30b13a22ffc9d1fd1a5590cff0b9f96b 467 TIGRFAM TIGR03356 BGL: beta-galactosidase 18 457 2.5E-179 T 28-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 Hamap MF_01987 Ribokinase [rbsK]. 2 283 24.732 T 28-03-2018 IPR011877 Ribokinase GO:0004747|GO:0006014 KEGG: 00030+2.7.1.15|Reactome: R-HSA-71336 CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 Gene3D G3DSA:3.40.1190.20 1 283 1.5E-71 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 SUPERFAMILY SSF53613 1 279 1.71E-72 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 Pfam PF00294 pfkB family carbohydrate kinase 1 276 1.5E-59 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 228 241 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 PRINTS PR00990 Ribokinase signature 104 117 3.4E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 PRINTS PR00990 Ribokinase signature 33 52 3.4E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 PRINTS PR00990 Ribokinase signature 166 181 3.4E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 PRINTS PR00990 Ribokinase signature 6 27 3.4E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS34920 630e908cd1121006a470e913e282d91e 283 PRINTS PR00990 Ribokinase signature 199 210 3.4E-30 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS19465 81c8e377823e1492eff75c9cce3e9999 107 SUPERFAMILY SSF56349 1 96 1.41E-16 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS19465 81c8e377823e1492eff75c9cce3e9999 107 Gene3D G3DSA:1.10.150.130 1 57 1.1E-6 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS19465 81c8e377823e1492eff75c9cce3e9999 107 Gene3D G3DSA:1.10.443.10 58 99 1.1E-5 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 ProSitePatterns PS00622 LuxR-type HTH domain signature. 844 871 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 860 872 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 830 844 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 844 860 1.4E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 SUPERFAMILY SSF46894 820 880 5.1E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 SUPERFAMILY SSF52540 128 225 3.1E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 SUPERFAMILY SSF52540 11 87 3.1E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 Gene3D G3DSA:3.40.50.300 11 288 4.8E-14 T 28-03-2018 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 Pfam PF00196 Bacterial regulatory proteins, luxR family 829 880 1.2E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 Pfam PF13191 AAA ATPase domain 10 166 1.4E-22 T 28-03-2018 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 Gene3D G3DSA:1.25.40.10 639 830 4.0E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 Gene3D G3DSA:1.10.10.10 831 883 6.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21410 dcc36ea92a0954bb15498217d5386b2f 893 SMART SM00421 827 884 1.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS13285 5ef6e18a09630f324738a5d6dde25755 128 SUPERFAMILY SSF54593 2 127 2.69E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS13285 5ef6e18a09630f324738a5d6dde25755 128 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 124 6.7E-15 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS13285 5ef6e18a09630f324738a5d6dde25755 128 Gene3D G3DSA:3.10.180.10 1 128 3.0E-27 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS19595 17d6e5505fc9e6d6e010c1c1f4c6f713 541 Gene3D G3DSA:3.40.605.10 21 306 6.9E-47 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS19595 17d6e5505fc9e6d6e010c1c1f4c6f713 541 Pfam PF00171 Aldehyde dehydrogenase family 64 506 5.7E-60 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS19595 17d6e5505fc9e6d6e010c1c1f4c6f713 541 Gene3D G3DSA:3.40.309.10 307 504 1.3E-34 T 28-03-2018 CNX65_RS19595 17d6e5505fc9e6d6e010c1c1f4c6f713 541 SUPERFAMILY SSF53720 62 522 6.15E-72 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS05940 5f59668218bfe19030d04f1589feca9d 181 Gene3D G3DSA:3.40.630.30 1 176 3.0E-33 T 28-03-2018 CNX65_RS05940 5f59668218bfe19030d04f1589feca9d 181 Pfam PF13302 Acetyltransferase (GNAT) domain 6 144 7.9E-28 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS05940 5f59668218bfe19030d04f1589feca9d 181 SUPERFAMILY SSF55729 2 167 2.8E-39 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS29915 73a7e86e9d117eb27abaa41c7b9d3c21 323 Gene3D G3DSA:3.40.30.10 54 254 5.0E-32 T 28-03-2018 CNX65_RS29915 73a7e86e9d117eb27abaa41c7b9d3c21 323 SUPERFAMILY SSF52833 57 165 1.96E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS29915 73a7e86e9d117eb27abaa41c7b9d3c21 323 Pfam PF00085 Thioredoxin 59 161 5.1E-12 T 28-03-2018 IPR013766 Thioredoxin domain GO:0045454 CNX65_RS29915 73a7e86e9d117eb27abaa41c7b9d3c21 323 Pfam PF14561 Tetratricopeptide repeat 244 323 2.5E-20 T 28-03-2018 CNX65_RS29915 73a7e86e9d117eb27abaa41c7b9d3c21 323 Gene3D G3DSA:1.10.1240.20 255 323 0.0039 T 28-03-2018 IPR012289 Lytic transglycosylase, superhelical linker GO:0004553|GO:0042597 CNX65_RS02735 abf18f6c536d99ac0d1c635780ffe02f 395 SUPERFAMILY SSF51338 12 66 9.22E-8 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02735 abf18f6c536d99ac0d1c635780ffe02f 395 Gene3D G3DSA:2.30.40.10 1 61 2.0E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02735 abf18f6c536d99ac0d1c635780ffe02f 395 Pfam PF07969 Amidohydrolase family 97 387 2.1E-18 T 28-03-2018 IPR013108 Amidohydrolase 3 CNX65_RS02735 abf18f6c536d99ac0d1c635780ffe02f 395 Gene3D G3DSA:3.20.20.140 62 347 4.1E-33 T 28-03-2018 CNX65_RS02735 abf18f6c536d99ac0d1c635780ffe02f 395 SUPERFAMILY SSF51556 54 356 1.47E-68 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS09650 7e4325c830d3bb90d4926a296fd6969b 130 Gene3D G3DSA:3.30.530.20 1 108 2.2E-8 T 28-03-2018 IPR023393 START-like domain CNX65_RS09650 7e4325c830d3bb90d4926a296fd6969b 130 SUPERFAMILY SSF55961 1 102 1.65E-7 T 28-03-2018 CNX65_RS05480 068a838e051b4a1bb2a1a84df5cd59d6 495 Pfam PF05235 CHAD domain 223 447 4.2E-58 T 28-03-2018 IPR007899 CHAD domain CNX65_RS05480 068a838e051b4a1bb2a1a84df5cd59d6 495 Pfam PF01928 CYTH domain 6 194 3.9E-12 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CNX65_RS05480 068a838e051b4a1bb2a1a84df5cd59d6 495 SUPERFAMILY SSF55154 5 208 5.01E-43 T 28-03-2018 IPR033469 CYTH-like domain Reactome: R-HSA-196819 CNX65_RS05480 068a838e051b4a1bb2a1a84df5cd59d6 495 Gene3D G3DSA:2.40.320.10 3 207 2.4E-35 T 28-03-2018 CNX65_RS05480 068a838e051b4a1bb2a1a84df5cd59d6 495 SMART SM00880 223 480 5.1E-70 T 28-03-2018 IPR007899 CHAD domain CNX65_RS05480 068a838e051b4a1bb2a1a84df5cd59d6 495 SMART SM01118 5 204 9.3E-13 T 28-03-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 SUPERFAMILY SSF47203 239 372 2.44E-13 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 240 371 1.0E-27 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 25 102 7.3E-7 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 SUPERFAMILY SSF56645 13 207 1.31E-29 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 Gene3D G3DSA:2.40.110.10 115 208 1.0E-12 T 28-03-2018 CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 Gene3D G3DSA:1.20.140.10 215 393 4.4E-13 T 28-03-2018 CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 PIRSF PIRSF016578 1 394 1.7E-115 T 28-03-2018 CNX65_RS20450 8199eb9e5cadc7740c51cbd8456ce56b 394 Gene3D G3DSA:1.10.540.10 4 110 5.9E-10 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS03090 1270c84a139f6da857afad37fab35f5d 166 Pfam PF00994 Probable molybdopterin binding domain 13 149 1.6E-24 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03090 1270c84a139f6da857afad37fab35f5d 166 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 10 149 3.8E-27 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03090 1270c84a139f6da857afad37fab35f5d 166 Gene3D G3DSA:3.40.980.10 3 164 6.0E-30 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03090 1270c84a139f6da857afad37fab35f5d 166 SUPERFAMILY SSF53218 10 160 1.57E-32 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03090 1270c84a139f6da857afad37fab35f5d 166 SMART SM00852 12 156 3.1E-14 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS32045 eb0f5bb6eaa3138e67187338822e7dfd 481 Gene3D G3DSA:3.40.605.10 2 266 5.3E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS32045 eb0f5bb6eaa3138e67187338822e7dfd 481 Gene3D G3DSA:3.40.309.10 267 460 2.4E-60 T 28-03-2018 CNX65_RS32045 eb0f5bb6eaa3138e67187338822e7dfd 481 SUPERFAMILY SSF53720 6 476 1.96E-135 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS32045 eb0f5bb6eaa3138e67187338822e7dfd 481 Pfam PF00171 Aldehyde dehydrogenase family 20 474 7.8E-138 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS12785 f00057ebcef15674a018375be2dbb399 161 Pfam PF01047 MarR family 43 96 1.1E-9 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS12785 f00057ebcef15674a018375be2dbb399 161 SUPERFAMILY SSF46785 42 144 1.27E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12785 f00057ebcef15674a018375be2dbb399 161 Gene3D G3DSA:1.10.10.10 1 150 3.2E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12785 f00057ebcef15674a018375be2dbb399 161 ProSitePatterns PS01117 MarR-type HTH domain signature. 71 105 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CNX65_RS12785 f00057ebcef15674a018375be2dbb399 161 SMART SM00347 32 132 5.3E-13 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS10475 cfabb9cf1d81c1c479ceb110fe43fc0a 336 Gene3D G3DSA:3.40.190.120 166 261 2.8E-33 T 28-03-2018 CNX65_RS10475 cfabb9cf1d81c1c479ceb110fe43fc0a 336 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 50 317 2.2E-60 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CNX65_RS10475 cfabb9cf1d81c1c479ceb110fe43fc0a 336 Gene3D G3DSA:3.40.190.10 45 165 2.9E-16 T 28-03-2018 CNX65_RS10475 cfabb9cf1d81c1c479ceb110fe43fc0a 336 SUPERFAMILY SSF53850 51 322 4.16E-60 T 28-03-2018 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 123 3.3E-68 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 Pfam PF00164 Ribosomal protein S12/S23 12 123 1.6E-43 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 PIRSF PIRSF002133 1 124 1.1E-54 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 Gene3D G3DSA:2.40.50.140 1 124 1.0E-64 T 28-03-2018 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 SUPERFAMILY SSF50249 2 123 1.97E-52 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 ProSitePatterns PS00055 Ribosomal protein S12 signature. 43 50 - T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 123 39.892 T 28-03-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 PRINTS PR01034 Ribosomal protein S12 signature 77 94 5.2E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 PRINTS PR01034 Ribosomal protein S12 signature 58 77 5.2E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 PRINTS PR01034 Ribosomal protein S12 signature 42 57 5.2E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 PRINTS PR01034 Ribosomal protein S12 signature 94 110 5.2E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 PRINTS PR01034 Ribosomal protein S12 signature 27 42 5.2E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32475 ead13fb6f42e17db6e045f9eb22c8743 124 PRINTS PR01034 Ribosomal protein S12 signature 110 122 5.2E-59 T 28-03-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 Pfam PF00072 Response regulator receiver domain 1 109 6.9E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 SUPERFAMILY SSF46894 124 218 1.59E-26 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 SMART SM00448 1 109 5.4E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 216 3.9E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 SMART SM00862 145 216 1.5E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 Gene3D G3DSA:3.40.50.2300 1 118 3.8E-35 T 28-03-2018 CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 SUPERFAMILY SSF52172 1 122 2.99E-39 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS30560 93df5bfe71ee7229570f2d1a6819427a 220 Gene3D G3DSA:1.10.10.10 119 220 1.4E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 PIRSF PIRSF004983 1 544 3.5E-139 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 499 2.7E-6 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 Gene3D G3DSA:3.40.50.970 1 201 2.8E-47 T 28-03-2018 CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 Gene3D G3DSA:3.40.50.970 337 542 1.9E-24 T 28-03-2018 CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 SUPERFAMILY SSF52518 8 183 4.12E-28 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 8 171 8.8E-27 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 539 33.181 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 Gene3D G3DSA:3.40.50.1220 208 336 4.5E-8 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 SUPERFAMILY SSF52518 351 526 2.98E-18 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS33025 ce6896f495f523f95f82a6231ec990f5 544 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 415 1.2E-110 T 28-03-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 CNX65_RS22395 756d898251d7c219e4d526e9c19e33a9 348 SUPERFAMILY SSF53383 2 343 1.67E-102 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS22395 756d898251d7c219e4d526e9c19e33a9 348 Pfam PF01212 Beta-eliminating lyase 4 288 6.3E-81 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CNX65_RS22395 756d898251d7c219e4d526e9c19e33a9 348 PIRSF PIRSF017617 1 348 7.7E-118 T 28-03-2018 IPR023603 Threonine aldolase CNX65_RS22395 756d898251d7c219e4d526e9c19e33a9 348 Gene3D G3DSA:3.90.1150.10 250 345 1.1E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS22395 756d898251d7c219e4d526e9c19e33a9 348 Gene3D G3DSA:3.40.640.10 1 249 3.5E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS12460 636c30a80f0e2011010c195ef2074f40 554 Gene3D G3DSA:3.10.105.10 318 524 3.4E-45 T 28-03-2018 CNX65_RS12460 636c30a80f0e2011010c195ef2074f40 554 PIRSF PIRSF002741 2 551 1.5E-69 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS12460 636c30a80f0e2011010c195ef2074f40 554 Gene3D G3DSA:3.90.76.10 64 175 1.8E-19 T 28-03-2018 CNX65_RS12460 636c30a80f0e2011010c195ef2074f40 554 SUPERFAMILY SSF53850 33 542 2.35E-94 T 28-03-2018 CNX65_RS12460 636c30a80f0e2011010c195ef2074f40 554 Gene3D G3DSA:3.40.190.10 176 317 3.0E-31 T 28-03-2018 CNX65_RS12460 636c30a80f0e2011010c195ef2074f40 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 82 470 1.1E-65 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS23320 08de27369835cec237b56c03c8caadd8 141 SUPERFAMILY SSF50242 19 121 1.63E-13 T 28-03-2018 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold CNX65_RS23320 08de27369835cec237b56c03c8caadd8 141 Pfam PF00965 Tissue inhibitor of metalloproteinase 18 117 4.4E-5 T 28-03-2018 IPR001820 Protease inhibitor I35 (TIMP) GO:0008191 CNX65_RS23320 08de27369835cec237b56c03c8caadd8 141 Gene3D G3DSA:2.40.50.120 36 121 1.5E-11 T 28-03-2018 CNX65_RS00120 372f95bdadfbc0ba137f9fd60826d0b0 488 Gene3D G3DSA:3.40.710.10 135 488 1.1E-85 T 28-03-2018 CNX65_RS00120 372f95bdadfbc0ba137f9fd60826d0b0 488 SUPERFAMILY SSF56601 96 486 1.2E-80 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS00120 372f95bdadfbc0ba137f9fd60826d0b0 488 Pfam PF00905 Penicillin binding protein transpeptidase domain 156 481 8.0E-66 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CNX65_RS00120 372f95bdadfbc0ba137f9fd60826d0b0 488 Gene3D G3DSA:3.90.1310.10 17 134 6.5E-24 T 28-03-2018 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 PIRSF PIRSF005578 1 264 1.4E-94 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 Pfam PF01728 FtsJ-like methyltransferase 63 244 1.7E-17 T 28-03-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 SMART SM00363 5 68 3.4E-4 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 SUPERFAMILY SSF53335 62 246 9.97E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 6 239 5.9E-60 T 28-03-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 Gene3D G3DSA:3.40.50.150 65 265 3.4E-52 T 28-03-2018 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 Pfam PF01479 S4 domain 6 47 1.1E-8 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 SUPERFAMILY SSF55174 5 59 6.06E-11 T 28-03-2018 CNX65_RS27095 b9553d83be7bd9c6074fc517e2b5ba0c 268 Gene3D G3DSA:3.10.290.10 2 64 3.0E-14 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS06775 1a5068390aa3ab243e90dfbaa4963273 234 Gene3D G3DSA:3.40.1130.10 1 226 2.9E-54 T 28-03-2018 CNX65_RS06775 1a5068390aa3ab243e90dfbaa4963273 234 Pfam PF01553 Acyltransferase 20 150 3.7E-26 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS06775 1a5068390aa3ab243e90dfbaa4963273 234 SUPERFAMILY SSF69593 3 215 2.48E-50 T 28-03-2018 CNX65_RS06775 1a5068390aa3ab243e90dfbaa4963273 234 SMART SM00563 34 153 5.8E-36 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 23 467 45.435 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 Gene3D G3DSA:3.60.20.10 24 255 6.5E-57 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 Pfam PF13522 Glutamine amidotransferase domain 81 221 8.8E-16 T 28-03-2018 CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 PIRSF PIRSF000485 20 479 1.5E-158 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 24 468 2.0E-157 T 28-03-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 Gene3D G3DSA:3.40.50.2020 256 453 8.9E-31 T 28-03-2018 CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 SUPERFAMILY SSF53271 262 476 5.24E-67 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS33905 ec38426f5d12b72df85f02aa232996a4 514 SUPERFAMILY SSF56235 24 279 2.14E-62 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS22210 096782ad0a35afdcd7ca1af367fd699c 180 SUPERFAMILY SSF46689 3 73 1.8E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22210 096782ad0a35afdcd7ca1af367fd699c 180 Gene3D G3DSA:1.10.10.60 2 53 1.3E-11 T 28-03-2018 CNX65_RS22210 096782ad0a35afdcd7ca1af367fd699c 180 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 49 4.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22210 096782ad0a35afdcd7ca1af367fd699c 180 SUPERFAMILY SSF48498 77 166 3.56E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS22210 096782ad0a35afdcd7ca1af367fd699c 180 Gene3D G3DSA:1.10.357.10 54 168 2.3E-14 T 28-03-2018 CNX65_RS22785 58bba1c4698bd6088f9a4200a2cfddf7 239 Gene3D G3DSA:3.20.20.370 7 238 7.5E-10 T 28-03-2018 CNX65_RS22785 58bba1c4698bd6088f9a4200a2cfddf7 239 SUPERFAMILY SSF88713 52 229 2.26E-8 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 SUPERFAMILY SSF56601 568 955 9.22E-50 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 Gene3D G3DSA:3.40.710.10 571 957 4.0E-34 T 28-03-2018 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 740 955 2.4E-50 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 577 730 9.9E-24 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 829 843 1.0E-20 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 844 858 1.0E-20 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 611 630 1.0E-20 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 772 794 1.0E-20 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 915 928 1.0E-20 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS01585 731250932f3387956db2745979b6ffeb 962 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 740 938 3.9E-46 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS27655 d15b0d112a9b029da8bc8061e5235e6a 120 Gene3D G3DSA:3.30.1310.10 4 102 2.7E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS27655 d15b0d112a9b029da8bc8061e5235e6a 120 Pfam PF02575 YbaB/EbfC DNA-binding family 16 98 1.7E-11 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS27655 d15b0d112a9b029da8bc8061e5235e6a 120 SUPERFAMILY SSF82607 9 98 2.09E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS34785 ed71c7ec8f886b591821c4623383de13 168 SUPERFAMILY SSF50249 6 168 4.21E-47 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS34785 ed71c7ec8f886b591821c4623383de13 168 Gene3D G3DSA:2.40.50.140 1 120 1.0E-40 T 28-03-2018 CNX65_RS34785 ed71c7ec8f886b591821c4623383de13 168 Pfam PF00436 Single-strand binding protein family 6 106 1.7E-29 T 28-03-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 CNX65_RS34785 ed71c7ec8f886b591821c4623383de13 168 Hamap MF_00984 Single-stranded DNA-binding protein. 4 113 30.33 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CNX65_RS34785 ed71c7ec8f886b591821c4623383de13 168 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 5 168 1.4E-33 T 28-03-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 CNX65_RS31965 6586593eef60ee22bf30ec5c67811b00 354 Gene3D G3DSA:3.40.800.20 22 333 6.2E-82 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS31965 6586593eef60ee22bf30ec5c67811b00 354 SUPERFAMILY SSF52768 2 320 3.5E-82 T 28-03-2018 CNX65_RS31965 6586593eef60ee22bf30ec5c67811b00 354 PRINTS PR01270 Histone deacetylase superfamily signature 166 181 4.4E-12 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS31965 6586593eef60ee22bf30ec5c67811b00 354 PRINTS PR01270 Histone deacetylase superfamily signature 134 157 4.4E-12 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS31965 6586593eef60ee22bf30ec5c67811b00 354 PRINTS PR01270 Histone deacetylase superfamily signature 250 260 4.4E-12 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS31965 6586593eef60ee22bf30ec5c67811b00 354 Pfam PF00850 Histone deacetylase domain 32 313 1.6E-60 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 Gene3D G3DSA:3.40.50.720 128 218 2.9E-4 T 28-03-2018 CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 Gene3D G3DSA:3.40.50.720 219 415 5.4E-52 T 28-03-2018 CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 358 374 8.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 259 8.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 404 421 8.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 384 403 8.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 437 457 8.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 313 324 8.5E-33 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 247 470 1.7E-43 T 28-03-2018 CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 SUPERFAMILY SSF51735 237 473 1.16E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 364 372 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 313 324 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 384 403 1.8E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 Gene3D G3DSA:3.40.50.720 416 474 8.8E-7 T 28-03-2018 CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 371 399 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS34465 5a0c1c629dd140284e51165ce507023b 477 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 241 418 8.0E-6 T 28-03-2018 CNX65_RS23050 b5a9e561af3745dee887f9a54fde2e61 192 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 69 6.1E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23050 b5a9e561af3745dee887f9a54fde2e61 192 ProSitePatterns PS01081 TetR-type HTH domain signature. 36 67 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS23050 b5a9e561af3745dee887f9a54fde2e61 192 SUPERFAMILY SSF48498 82 190 1.33E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS23050 b5a9e561af3745dee887f9a54fde2e61 192 SUPERFAMILY SSF46689 15 78 1.75E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23050 b5a9e561af3745dee887f9a54fde2e61 192 Gene3D G3DSA:1.10.357.10 73 192 1.1E-13 T 28-03-2018 CNX65_RS23050 b5a9e561af3745dee887f9a54fde2e61 192 Gene3D G3DSA:1.10.10.60 16 72 4.0E-17 T 28-03-2018 CNX65_RS23050 b5a9e561af3745dee887f9a54fde2e61 192 Pfam PF16859 Bacterial transcriptional repressor C-terminal 82 184 2.7E-13 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS16635 b420c0e09e3e6f1d959cc9b78989b20a 413 Pfam PF07728 AAA domain (dynein-related subfamily) 49 182 2.1E-7 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CNX65_RS16635 b420c0e09e3e6f1d959cc9b78989b20a 413 SUPERFAMILY SSF52540 35 219 2.04E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16635 b420c0e09e3e6f1d959cc9b78989b20a 413 Gene3D G3DSA:3.40.50.300 34 187 3.3E-18 T 28-03-2018 CNX65_RS02170 529437bcad1cea46db47c0ee15cad778 94 Pfam PF11662 Protein of unknown function (DUF3263) 14 85 9.0E-36 T 28-03-2018 IPR021678 Protein of unknown function DUF3263 CNX65_RS24760 82150d4e123fb0fbc96199d3af5c5f90 307 Gene3D G3DSA:3.40.50.300 12 204 1.2E-5 T 28-03-2018 CNX65_RS24760 82150d4e123fb0fbc96199d3af5c5f90 307 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 6 283 1.3E-93 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CNX65_RS24760 82150d4e123fb0fbc96199d3af5c5f90 307 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 4 286 36.484 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CNX65_RS24760 82150d4e123fb0fbc96199d3af5c5f90 307 Pfam PF02401 LytB protein 6 282 1.3E-87 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CNX65_RS24760 82150d4e123fb0fbc96199d3af5c5f90 307 Gene3D G3DSA:3.40.50.2300 205 271 0.012 T 28-03-2018 CNX65_RS08855 ba735ecc7b161a9e1db44659be569789 130 SUPERFAMILY SSF50475 8 129 2.22E-25 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS08855 ba735ecc7b161a9e1db44659be569789 130 Gene3D G3DSA:2.30.110.10 3 128 2.3E-28 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS08855 ba735ecc7b161a9e1db44659be569789 130 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 94 1.9E-10 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS11710 48c4505076a753045655f24ec8335d55 429 Pfam PF05977 Transmembrane secretion effector 41 420 7.8E-33 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS11710 48c4505076a753045655f24ec8335d55 429 Gene3D G3DSA:1.20.1250.20 241 427 3.8E-15 T 28-03-2018 CNX65_RS11710 48c4505076a753045655f24ec8335d55 429 Gene3D G3DSA:1.20.1250.20 38 238 9.1E-18 T 28-03-2018 CNX65_RS11710 48c4505076a753045655f24ec8335d55 429 SUPERFAMILY SSF103473 47 424 6.28E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS24795 84dd7ed67672d6c3fd68d737d46d273d 194 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 5.6E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24795 84dd7ed67672d6c3fd68d737d46d273d 194 SUPERFAMILY SSF48498 81 192 2.89E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS24795 84dd7ed67672d6c3fd68d737d46d273d 194 Gene3D G3DSA:1.10.357.10 7 193 1.4E-27 T 28-03-2018 CNX65_RS24795 84dd7ed67672d6c3fd68d737d46d273d 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 9.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24795 84dd7ed67672d6c3fd68d737d46d273d 194 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 9.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24795 84dd7ed67672d6c3fd68d737d46d273d 194 SUPERFAMILY SSF46689 6 83 6.67E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS21335 7cfe983f3fc7d8cdcf0e95d03e7bedbb 284 Pfam PF01596 O-methyltransferase 98 276 2.6E-41 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CNX65_RS21335 7cfe983f3fc7d8cdcf0e95d03e7bedbb 284 Gene3D G3DSA:3.40.50.150 53 281 3.5E-36 T 28-03-2018 CNX65_RS21335 7cfe983f3fc7d8cdcf0e95d03e7bedbb 284 SUPERFAMILY SSF53335 97 276 5.58E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS17205 8b14e29b6c7798328dd00a6b886325f8 518 SUPERFAMILY SSF51556 57 109 1.0E-32 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS17205 8b14e29b6c7798328dd00a6b886325f8 518 SUPERFAMILY SSF51556 175 449 1.0E-32 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS17205 8b14e29b6c7798328dd00a6b886325f8 518 Pfam PF07969 Amidohydrolase family 46 514 3.2E-84 T 28-03-2018 IPR013108 Amidohydrolase 3 CNX65_RS17205 8b14e29b6c7798328dd00a6b886325f8 518 Gene3D G3DSA:2.30.40.10 1 69 3.4E-15 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS17205 8b14e29b6c7798328dd00a6b886325f8 518 Gene3D G3DSA:3.20.20.140 70 450 8.5E-42 T 28-03-2018 CNX65_RS17205 8b14e29b6c7798328dd00a6b886325f8 518 SUPERFAMILY SSF51338 3 74 2.99E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS25105 42eab9bf8c24a3f2c3760ff37cf7431d 315 SUPERFAMILY SSF56563 4 233 3.66E-8 T 28-03-2018 CNX65_RS05085 5c79bb1275cc66df7039bbd911a21067 211 Gene3D G3DSA:1.20.1540.10 21 199 2.6E-18 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS05085 5c79bb1275cc66df7039bbd911a21067 211 SUPERFAMILY SSF144091 29 196 2.35E-26 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS05085 5c79bb1275cc66df7039bbd911a21067 211 Pfam PF01694 Rhomboid family 63 198 3.6E-23 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS07640 0d7a5fd3c4baf48f64ba779db66a3e28 137 Gene3D G3DSA:3.40.50.1010 2 135 5.1E-18 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS07640 0d7a5fd3c4baf48f64ba779db66a3e28 137 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 131 10.109 T 28-03-2018 IPR022907 VapC family GO:0004540 CNX65_RS07640 0d7a5fd3c4baf48f64ba779db66a3e28 137 SUPERFAMILY SSF88723 5 127 1.01E-18 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS07640 0d7a5fd3c4baf48f64ba779db66a3e28 137 Pfam PF01850 PIN domain 8 122 3.2E-7 T 28-03-2018 IPR002716 PIN domain CNX65_RS18515 0939f027bf2266e299b6bca810e45e58 313 Pfam PF07730 Histidine kinase 119 182 1.1E-7 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS18515 0939f027bf2266e299b6bca810e45e58 313 SUPERFAMILY SSF55874 200 307 2.13E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18515 0939f027bf2266e299b6bca810e45e58 313 Gene3D G3DSA:3.30.565.10 192 311 1.9E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS08215 e84186b6df25f50e3e3f53c7829d7c79 189 Gene3D G3DSA:3.90.1720.10 41 183 6.6E-7 T 28-03-2018 CNX65_RS18335 2e43fb851c2537d8f3deda04a431b365 296 Pfam PF00975 Thioesterase domain 67 288 8.6E-33 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS18335 2e43fb851c2537d8f3deda04a431b365 296 SUPERFAMILY SSF53474 68 290 5.31E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18335 2e43fb851c2537d8f3deda04a431b365 296 SMART SM00824 Thioesterase 69 290 0.0098 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CNX65_RS18335 2e43fb851c2537d8f3deda04a431b365 296 Gene3D G3DSA:3.40.50.1820 46 292 1.7E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS18450 403413acd992837e0e27342df384b942 422 Gene3D G3DSA:1.20.1250.20 235 422 7.1E-19 T 28-03-2018 CNX65_RS18450 403413acd992837e0e27342df384b942 422 Gene3D G3DSA:1.20.1250.20 29 231 5.0E-12 T 28-03-2018 CNX65_RS18450 403413acd992837e0e27342df384b942 422 SUPERFAMILY SSF103473 35 417 2.09E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS18450 403413acd992837e0e27342df384b942 422 Pfam PF07690 Major Facilitator Superfamily 39 377 7.5E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS00090 7510f05525acf9b7609d468843b417d8 259 Gene3D G3DSA:2.40.260.10 63 253 2.0E-41 T 28-03-2018 IPR023365 Sortase domain CNX65_RS00090 7510f05525acf9b7609d468843b417d8 259 SUPERFAMILY SSF63817 44 242 1.02E-27 T 28-03-2018 IPR023365 Sortase domain CNX65_RS00090 7510f05525acf9b7609d468843b417d8 259 Pfam PF04203 Sortase family 76 241 3.4E-30 T 28-03-2018 IPR005754 Sortase family CNX65_RS24300 aa62c757b5ab70a40d6c414dee2565fc 845 Gene3D G3DSA:1.25.40.10 236 535 6.4E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS24300 aa62c757b5ab70a40d6c414dee2565fc 845 Gene3D G3DSA:1.25.40.10 550 760 3.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS22795 4485ba1b904c86fdd5fa0bc16ebd01ea 606 ProSitePatterns PS00211 ABC transporters family signature. 491 505 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS22795 4485ba1b904c86fdd5fa0bc16ebd01ea 606 SUPERFAMILY SSF90123 21 311 5.23E-12 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS22795 4485ba1b904c86fdd5fa0bc16ebd01ea 606 SMART SM00382 375 568 1.8E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS22795 4485ba1b904c86fdd5fa0bc16ebd01ea 606 Gene3D G3DSA:1.20.1560.10 8 326 1.6E-13 T 28-03-2018 CNX65_RS22795 4485ba1b904c86fdd5fa0bc16ebd01ea 606 Pfam PF00005 ABC transporter 366 522 1.7E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS22795 4485ba1b904c86fdd5fa0bc16ebd01ea 606 Gene3D G3DSA:3.40.50.300 346 600 2.1E-65 T 28-03-2018 CNX65_RS22795 4485ba1b904c86fdd5fa0bc16ebd01ea 606 SUPERFAMILY SSF52540 345 592 9.63E-72 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08630 2af310b7d85b1564d1814d596d707f65 91 Gene3D G3DSA:3.10.290.10 1 71 3.1E-18 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS08630 2af310b7d85b1564d1814d596d707f65 91 SUPERFAMILY SSF55174 3 69 3.14E-18 T 28-03-2018 CNX65_RS08630 2af310b7d85b1564d1814d596d707f65 91 SMART SM00363 13 75 6.3E-5 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS08630 2af310b7d85b1564d1814d596d707f65 91 Pfam PF13275 S4 domain 6 68 5.7E-24 T 28-03-2018 CNX65_RS07125 52d6b39f7a9befde72532d3fe7c79ade 416 Pfam PF05977 Transmembrane secretion effector 6 405 9.9E-26 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS07125 52d6b39f7a9befde72532d3fe7c79ade 416 SUPERFAMILY SSF103473 7 401 2.09E-42 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS07125 52d6b39f7a9befde72532d3fe7c79ade 416 Gene3D G3DSA:1.20.1250.20 210 413 4.0E-18 T 28-03-2018 CNX65_RS07125 52d6b39f7a9befde72532d3fe7c79ade 416 Gene3D G3DSA:1.20.1250.20 1 202 2.6E-17 T 28-03-2018 CNX65_RS15585 b3712452a1ecde56f828cf96372bd570 276 Gene3D G3DSA:1.10.3720.10 11 275 9.9E-32 T 28-03-2018 CNX65_RS15585 b3712452a1ecde56f828cf96372bd570 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 92 265 1.4E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS15585 b3712452a1ecde56f828cf96372bd570 276 SUPERFAMILY SSF161098 68 256 3.27E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS25410 58d2b95191642f4279eed3dd20892641 749 SUPERFAMILY SSF51445 27 665 2.93E-119 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS25410 58d2b95191642f4279eed3dd20892641 749 Pfam PF00128 Alpha amylase, catalytic domain 48 226 2.6E-16 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS25410 58d2b95191642f4279eed3dd20892641 749 Gene3D G3DSA:3.20.20.80 34 665 6.4E-101 T 28-03-2018 CNX65_RS25410 58d2b95191642f4279eed3dd20892641 749 SMART SM00642 34 651 2.3E-6 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS25410 58d2b95191642f4279eed3dd20892641 749 TIGRFAM TIGR02401 trehalose_TreY: malto-oligosyltrehalose synthase 165 746 2.0E-187 T 28-03-2018 IPR012767 Maltooligosyl trehalose synthase KEGG: 00500+5.4.99.15|MetaCyc: PWY-2661 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 SMART SM00421 151 208 3.1E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 SUPERFAMILY SSF46894 142 214 6.46E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 Gene3D G3DSA:1.10.10.10 135 213 3.4E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 SUPERFAMILY SSF52172 3 134 4.55E-31 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 184 196 1.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 184 1.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 154 168 1.3E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 208 4.0E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 ProSitePatterns PS00622 LuxR-type HTH domain signature. 168 195 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 Pfam PF00072 Response regulator receiver domain 5 117 1.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 Gene3D G3DSA:3.40.50.2300 2 134 1.2E-33 T 28-03-2018 CNX65_RS14950 0564ee02e6f075e015be24af4ef9d056 223 SMART SM00448 3 116 9.7E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS20055 26292e94839805249d4c49b01b97093d 269 Gene3D G3DSA:3.20.20.150 1 267 9.4E-52 T 28-03-2018 CNX65_RS20055 26292e94839805249d4c49b01b97093d 269 Pfam PF01261 Xylose isomerase-like TIM barrel 21 211 1.6E-29 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS20055 26292e94839805249d4c49b01b97093d 269 SUPERFAMILY SSF51658 4 257 2.36E-54 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS25230 3a8d8035016b1e9e9835c8bfd4b6bf8f 195 Pfam PF01810 LysE type translocator 12 194 1.1E-36 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 ProDom PD003367 URICASE OXIDOREDUCTASE URATE OXIDASE METABOLISM PURINE PEROXISOME ACETYLATION II DIRECT 174 271 4.0E-26 T 28-03-2018 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 PRINTS PR00093 Uricase signature 86 99 2.7E-19 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 PRINTS PR00093 Uricase signature 144 160 2.7E-19 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 PRINTS PR00093 Uricase signature 11 22 2.7E-19 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 PRINTS PR00093 Uricase signature 50 64 2.7E-19 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 PRINTS PR00093 Uricase signature 160 172 2.7E-19 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 TIGRFAM TIGR03383 urate_oxi: urate oxidase 6 274 2.8E-102 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 ProSitePatterns PS00366 Uricase signature. 144 171 - T 28-03-2018 IPR019842 Uricase, conserved site GO:0004846|GO:0006144|GO:0055114 KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 Gene3D G3DSA:3.10.270.10 1 282 2.4E-111 T 28-03-2018 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 SUPERFAMILY SSF55620 135 287 3.0E-55 T 28-03-2018 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 PIRSF PIRSF000241 2 283 4.6E-96 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 Pfam PF01014 Uricase 9 128 1.9E-15 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 Pfam PF01014 Uricase 138 272 1.3E-34 T 28-03-2018 IPR002042 Uricase KEGG: 00230+1.7.3.3|KEGG: 00232+1.7.3.3|MetaCyc: PWY-5691 CNX65_RS29155 6d55abd432b76893909a5f3f6983ea6f 293 SUPERFAMILY SSF55620 3 126 3.2E-41 T 28-03-2018 CNX65_RS10410 ac5b9c7540b3bc6659fae7614b3c34ce 233 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 3 223 3.5E-59 T 28-03-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 KEGG: 00910+1.7.99.4 CNX65_RS10410 ac5b9c7540b3bc6659fae7614b3c34ce 233 Gene3D G3DSA:1.20.950.20 1 214 3.0E-46 T 28-03-2018 CNX65_RS10410 ac5b9c7540b3bc6659fae7614b3c34ce 233 SUPERFAMILY SSF103501 2 222 4.97E-65 T 28-03-2018 IPR023234 NarG-like domain CNX65_RS10410 ac5b9c7540b3bc6659fae7614b3c34ce 233 Pfam PF02665 Nitrate reductase gamma subunit 3 222 1.0E-84 T 28-03-2018 IPR023234 NarG-like domain CNX65_RS06655 ae426c23c5935253389f56fbe244c429 147 Gene3D G3DSA:3.10.450.50 2 144 7.8E-26 T 28-03-2018 CNX65_RS06655 ae426c23c5935253389f56fbe244c429 147 SUPERFAMILY SSF54427 6 132 3.39E-33 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS06655 ae426c23c5935253389f56fbe244c429 147 Pfam PF12680 SnoaL-like domain 10 117 8.8E-16 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS05620 b59c83b35a9d17dc08591516d6492dc7 1651 Pfam PF05088 Bacterial NAD-glutamate dehydrogenase 89 1647 0.0 T 28-03-2018 IPR028971 NAD-glutamate dehydrogenase GO:0004352|GO:0019551 KEGG: 00220+1.4.1.2|KEGG: 00250+1.4.1.2|KEGG: 00430+1.4.1.2|KEGG: 00910+1.4.1.2|MetaCyc: PWY-5022|MetaCyc: PWY-6728|MetaCyc: PWY-7126 CNX65_RS05620 b59c83b35a9d17dc08591516d6492dc7 1651 PIRSF PIRSF036761 16 1651 0.0 T 28-03-2018 IPR007780 NAD-glutamate dehydrogenase, bacteria GO:0004352|GO:0019551 CNX65_RS05620 b59c83b35a9d17dc08591516d6492dc7 1651 SUPERFAMILY SSF53223 791 989 2.01E-23 T 28-03-2018 CNX65_RS05620 b59c83b35a9d17dc08591516d6492dc7 1651 Gene3D G3DSA:3.40.50.720 971 1280 3.8E-51 T 28-03-2018 CNX65_RS05620 b59c83b35a9d17dc08591516d6492dc7 1651 SUPERFAMILY SSF51735 1118 1266 1.58E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS05620 b59c83b35a9d17dc08591516d6492dc7 1651 SUPERFAMILY SSF51735 978 1080 1.58E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS05620 b59c83b35a9d17dc08591516d6492dc7 1651 Gene3D G3DSA:3.40.50.10860 823 954 5.6E-4 T 28-03-2018 CNX65_RS13475 6ee98d570c0f72616076c32c69ab8f7a 442 SUPERFAMILY SSF51905 189 344 3.15E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13475 6ee98d570c0f72616076c32c69ab8f7a 442 Gene3D G3DSA:3.50.50.60 2 212 5.3E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13475 6ee98d570c0f72616076c32c69ab8f7a 442 Gene3D G3DSA:3.50.50.60 213 441 5.6E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13475 6ee98d570c0f72616076c32c69ab8f7a 442 SUPERFAMILY SSF51905 8 236 3.42E-22 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13475 6ee98d570c0f72616076c32c69ab8f7a 442 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 6 345 9.4E-93 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CNX65_RS03450 f9dc27528fd5f473f416ce639925c56b 207 SUPERFAMILY SSF55136 121 194 4.19E-8 T 28-03-2018 CNX65_RS03450 f9dc27528fd5f473f416ce639925c56b 207 Pfam PF06445 GyrI-like small molecule binding domain 20 200 4.9E-16 T 28-03-2018 IPR029442 GyrI-like small molecule binding domain CNX65_RS03450 f9dc27528fd5f473f416ce639925c56b 207 Gene3D G3DSA:3.20.80.10 1 204 2.1E-54 T 28-03-2018 IPR011256 Regulatory factor, effector binding domain CNX65_RS11370 d849d1523911f2651e61078b1c227b3f 255 Pfam PF12730 ABC-2 family transporter protein 4 173 2.9E-9 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 Gene3D G3DSA:1.10.630.10 8 409 1.2E-73 T 28-03-2018 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 SUPERFAMILY SSF48264 14 407 7.2E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 94 105 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 161 176 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 352 361 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 144 160 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 286 297 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 303 330 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 331 346 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 204 226 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 PRINTS PR00359 B-class P450 signature 361 372 1.0E-51 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 Pfam PF00067 Cytochrome P450 88 375 1.5E-22 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS00390 fd304f824091e4f649c3d5b8f4063391 410 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 354 363 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS20925 b12c3150faa44729948604bae2cd39e9 315 PIRSF PIRSF000189 1 313 5.4E-64 T 28-03-2018 IPR023209 D-amino-acid oxidase GO:0003884|GO:0046416|GO:0071949 Reactome: R-HSA-389661 CNX65_RS20925 b12c3150faa44729948604bae2cd39e9 315 Pfam PF01266 FAD dependent oxidoreductase 4 303 9.2E-29 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS20925 b12c3150faa44729948604bae2cd39e9 315 SUPERFAMILY SSF51971 256 310 7.3E-24 T 28-03-2018 CNX65_RS20925 b12c3150faa44729948604bae2cd39e9 315 SUPERFAMILY SSF51971 3 195 7.3E-24 T 28-03-2018 CNX65_RS20925 b12c3150faa44729948604bae2cd39e9 315 SUPERFAMILY SSF54373 182 271 1.44E-19 T 28-03-2018 CNX65_RS20925 b12c3150faa44729948604bae2cd39e9 315 Gene3D G3DSA:3.50.50.60 1 87 1.2E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20925 b12c3150faa44729948604bae2cd39e9 315 Gene3D G3DSA:3.30.9.10 88 269 6.3E-32 T 28-03-2018 CNX65_RS12845 24059a8693ab35f87549c0f7d7d9db02 411 Pfam PF07690 Major Facilitator Superfamily 24 362 8.2E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS12845 24059a8693ab35f87549c0f7d7d9db02 411 Gene3D G3DSA:1.20.1250.20 17 208 1.6E-19 T 28-03-2018 CNX65_RS12845 24059a8693ab35f87549c0f7d7d9db02 411 Gene3D G3DSA:1.20.1250.20 220 408 7.6E-19 T 28-03-2018 CNX65_RS12845 24059a8693ab35f87549c0f7d7d9db02 411 SUPERFAMILY SSF103473 19 404 1.23E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS33995 d8e001e9a919416594d374f45e74dc5f 79 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 4 74 6.9E-25 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33995 d8e001e9a919416594d374f45e74dc5f 79 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 4 74 2.9E-14 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33995 d8e001e9a919416594d374f45e74dc5f 79 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 11 75 4.0E-20 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33995 d8e001e9a919416594d374f45e74dc5f 79 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 76 19.471 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS33995 d8e001e9a919416594d374f45e74dc5f 79 SUPERFAMILY SSF82697 3 76 1.92E-22 T 28-03-2018 CNX65_RS33995 d8e001e9a919416594d374f45e74dc5f 79 Gene3D G3DSA:3.30.1280.10 3 76 7.3E-26 T 28-03-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 CNX65_RS10680 899176d73d517cc66c999a96f487a11e 125 Gene3D G3DSA:2.30.29.50 14 102 1.5E-32 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain CNX65_RS10680 899176d73d517cc66c999a96f487a11e 125 SUPERFAMILY SSF50729 13 124 2.95E-36 T 28-03-2018 IPR011993 PH domain-like CNX65_RS10680 899176d73d517cc66c999a96f487a11e 125 Pfam PF08000 Bacterial PH domain 6 123 9.1E-40 T 28-03-2018 IPR012544 Bacterial Pleckstrin homology domain CNX65_RS23200 5a01d06d22694df8de6c121ebd98457e 534 Gene3D G3DSA:3.40.50.980 8 163 4.1E-17 T 28-03-2018 CNX65_RS23200 5a01d06d22694df8de6c121ebd98457e 534 Gene3D G3DSA:3.30.300.30 419 532 8.9E-4 T 28-03-2018 CNX65_RS23200 5a01d06d22694df8de6c121ebd98457e 534 Gene3D G3DSA:3.40.50.980 164 352 1.8E-26 T 28-03-2018 CNX65_RS23200 5a01d06d22694df8de6c121ebd98457e 534 SUPERFAMILY SSF56801 294 523 5.1E-61 T 28-03-2018 CNX65_RS23200 5a01d06d22694df8de6c121ebd98457e 534 SUPERFAMILY SSF56801 26 260 5.1E-61 T 28-03-2018 CNX65_RS23200 5a01d06d22694df8de6c121ebd98457e 534 Pfam PF00501 AMP-binding enzyme 34 424 1.1E-42 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS09555 e98ca35b412275da1afb31f1d600636f 123 Pfam PF00582 Universal stress protein family 6 105 1.9E-9 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS09555 e98ca35b412275da1afb31f1d600636f 123 SUPERFAMILY SSF52402 6 116 1.67E-11 T 28-03-2018 CNX65_RS09555 e98ca35b412275da1afb31f1d600636f 123 Gene3D G3DSA:3.40.50.620 2 114 5.1E-13 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS22365 e0722684d2825ea9f0a2ea3103917614 255 Gene3D G3DSA:3.40.50.1820 5 246 3.1E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22365 e0722684d2825ea9f0a2ea3103917614 255 SUPERFAMILY SSF53474 5 239 9.42E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22365 e0722684d2825ea9f0a2ea3103917614 255 Pfam PF00975 Thioesterase domain 21 238 2.1E-23 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 SUPERFAMILY SSF51735 5 241 3.29E-76 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 Gene3D G3DSA:3.40.50.720 1 44 8.5E-11 T 28-03-2018 CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 Gene3D G3DSA:3.40.50.720 45 243 2.5E-57 T 28-03-2018 CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 225 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 79 90 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS19905 ac04bf462e7d720a72ac5160174fd54c 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 2.9E-60 T 28-03-2018 CNX65_RS10905 5a9b439d36a9196c70def542bff6eed5 254 Pfam PF02146 Sir2 family 12 190 2.9E-44 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CNX65_RS10905 5a9b439d36a9196c70def542bff6eed5 254 SUPERFAMILY SSF52467 3 236 4.67E-66 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS10905 5a9b439d36a9196c70def542bff6eed5 254 Gene3D G3DSA:3.40.50.1220 1 231 3.4E-58 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 Gene3D G3DSA:3.40.630.10 242 386 5.1E-15 T 28-03-2018 CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 SUPERFAMILY SSF55031 170 274 4.34E-20 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 Gene3D G3DSA:3.40.630.10 3 241 3.6E-46 T 28-03-2018 CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 Pfam PF07687 Peptidase dimerisation domain 169 262 1.2E-7 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 PIRSF PIRSF037226 2 385 8.6E-139 T 28-03-2018 IPR017144 Peptidase M20A, amidohydrolase, predicted CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 Pfam PF01546 Peptidase family M20/M25/M40 84 328 8.5E-9 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 21 346 6.6E-58 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 SUPERFAMILY SSF53187 9 181 2.06E-59 T 28-03-2018 CNX65_RS31480 d19a123349ea56ecce084e233231e6b4 391 SUPERFAMILY SSF53187 281 373 2.06E-59 T 28-03-2018 CNX65_RS20740 41c723d0ec41986d868cecec0b0dd53d 101 Pfam PF13601 Winged helix DNA-binding domain 18 96 2.9E-22 T 28-03-2018 IPR027395 Winged helix DNA-binding domain CNX65_RS20740 41c723d0ec41986d868cecec0b0dd53d 101 SUPERFAMILY SSF46785 5 97 5.37E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20740 41c723d0ec41986d868cecec0b0dd53d 101 Gene3D G3DSA:1.10.10.10 2 101 1.8E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 465 542 4.8E-15 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 Gene3D G3DSA:3.40.50.980 206 367 3.2E-34 T 28-03-2018 CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 SUPERFAMILY SSF56801 22 553 1.44E-134 T 28-03-2018 CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 Gene3D G3DSA:3.40.50.980 38 205 3.5E-37 T 28-03-2018 CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 Pfam PF00501 AMP-binding enzyme 47 456 3.5E-83 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 Gene3D G3DSA:2.30.38.10 369 450 1.2E-19 T 28-03-2018 CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 ProSitePatterns PS00455 Putative AMP-binding domain signature. 202 213 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS13820 96e095434600de9a3148d0656408d7eb 558 Gene3D G3DSA:3.30.300.30 451 558 7.2E-26 T 28-03-2018 CNX65_RS33250 b805065467339b5c8ab587da1586390b 277 Pfam PF01261 Xylose isomerase-like TIM barrel 33 224 4.9E-19 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS33250 b805065467339b5c8ab587da1586390b 277 Gene3D G3DSA:3.20.20.150 7 276 7.0E-47 T 28-03-2018 CNX65_RS33250 b805065467339b5c8ab587da1586390b 277 SUPERFAMILY SSF51658 10 261 3.45E-41 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 Gene3D G3DSA:1.10.287.130 360 430 1.9E-13 T 28-03-2018 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 SMART SM00304 318 369 1.1E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 SUPERFAMILY SSF158472 320 366 5.62E-7 T 28-03-2018 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 SMART SM00387 479 591 2.3E-41 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 SUPERFAMILY SSF47384 353 434 8.44E-16 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 SMART SM00388 370 434 1.1E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 479 589 2.1E-26 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 534 544 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 575 588 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 530 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 569 1.5E-18 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 Pfam PF00512 His Kinase A (phospho-acceptor) domain 371 434 6.8E-13 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 SUPERFAMILY SSF55874 423 589 2.88E-50 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 Gene3D G3DSA:3.30.565.10 438 592 2.7E-46 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12975 a63caf81f8c059cf304e66dbda364eda 592 Pfam PF00672 HAMP domain 320 365 3.2E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS18925 55a1500ebe11372c10bb8ee48df4d116 133 SMART SM00886 2 94 1.3E-7 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel CNX65_RS18925 55a1500ebe11372c10bb8ee48df4d116 133 SUPERFAMILY SSF54909 2 91 3.58E-10 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS18925 55a1500ebe11372c10bb8ee48df4d116 133 Gene3D G3DSA:3.30.70.100 1 98 5.5E-12 T 28-03-2018 CNX65_RS18925 55a1500ebe11372c10bb8ee48df4d116 133 Pfam PF07876 Stress responsive A/B Barrel Domain 5 85 7.9E-11 T 28-03-2018 IPR013097 Stress responsive alpha-beta barrel CNX65_RS11865 d2d2caaa1343272620cd6ab729bc87ea 90 Pfam PF01313 Bacterial export proteins, family 3 6 77 2.3E-26 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CNX65_RS11865 d2d2caaa1343272620cd6ab729bc87ea 90 PIRSF PIRSF004669 1 89 3.0E-31 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CNX65_RS11865 d2d2caaa1343272620cd6ab729bc87ea 90 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 8.7E-19 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CNX65_RS11865 d2d2caaa1343272620cd6ab729bc87ea 90 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 8.7E-19 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CNX65_RS11865 d2d2caaa1343272620cd6ab729bc87ea 90 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 8.7E-19 T 28-03-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 CNX65_RS11865 d2d2caaa1343272620cd6ab729bc87ea 90 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 8.5E-27 T 28-03-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 CNX65_RS29375 42b3e7f400765b61ed762bb3d096b1f7 278 PRINTS PR00412 Epoxide hydrolase signature 40 58 1.0E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS29375 42b3e7f400765b61ed762bb3d096b1f7 278 PRINTS PR00412 Epoxide hydrolase signature 60 75 1.0E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS29375 42b3e7f400765b61ed762bb3d096b1f7 278 PRINTS PR00412 Epoxide hydrolase signature 254 276 1.0E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS29375 42b3e7f400765b61ed762bb3d096b1f7 278 SUPERFAMILY SSF53474 9 278 6.16E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29375 42b3e7f400765b61ed762bb3d096b1f7 278 Gene3D G3DSA:3.40.50.1820 5 278 5.2E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29375 42b3e7f400765b61ed762bb3d096b1f7 278 Pfam PF00561 alpha/beta hydrolase fold 34 140 1.2E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 Gene3D G3DSA:3.40.190.10 1 126 1.7E-9 T 28-03-2018 CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 Pfam PF00092 von Willebrand factor type A domain 348 508 3.3E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 Pfam PF13531 Bacterial extracellular solute-binding protein 34 299 2.0E-20 T 28-03-2018 CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 Gene3D G3DSA:3.40.190.10 191 308 1.1E-4 T 28-03-2018 CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 Gene3D G3DSA:3.40.50.410 337 525 3.2E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 SUPERFAMILY SSF53850 201 338 5.94E-14 T 28-03-2018 CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 SUPERFAMILY SSF53850 33 173 5.94E-14 T 28-03-2018 CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 SUPERFAMILY SSF53300 346 523 4.01E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS12590 5615e58731135aa74fb47fe2ec3280c8 527 SMART SM00327 343 520 9.0E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 SUPERFAMILY SSF118215 16 411 4.32E-101 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 Pfam PF00375 Sodium:dicarboxylate symporter family 16 411 2.1E-94 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 PRINTS PR00173 Glutamate-aspartate symporter signature 14 34 6.4E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 PRINTS PR00173 Glutamate-aspartate symporter signature 81 106 6.4E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 PRINTS PR00173 Glutamate-aspartate symporter signature 199 218 6.4E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 PRINTS PR00173 Glutamate-aspartate symporter signature 334 353 6.4E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 PRINTS PR00173 Glutamate-aspartate symporter signature 299 325 6.4E-24 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 ProSitePatterns PS00714 Sodium:dicarboxylate symporter family signature 2. 302 325 - T 28-03-2018 IPR018107 Sodium:dicarboxylate symporter, conserved site CNX65_RS27905 b7c098a969c3166118fef97d9a85d674 456 Gene3D G3DSA:1.10.3860.10 10 418 5.5E-101 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS09975 82bb5c280390c32c870946b3ca6166db 302 Gene3D G3DSA:3.40.50.720 9 296 5.1E-33 T 28-03-2018 CNX65_RS09975 82bb5c280390c32c870946b3ca6166db 302 SUPERFAMILY SSF51735 9 277 4.07E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09975 82bb5c280390c32c870946b3ca6166db 302 Pfam PF04321 RmlD substrate binding domain 10 277 1.5E-36 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 Pfam PF00082 Subtilase family 214 464 1.5E-56 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 SUPERFAMILY SSF52743 199 475 4.45E-79 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 Gene3D G3DSA:2.60.40.10 478 575 1.8E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 415 425 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 Gene3D G3DSA:2.60.40.650 973 1065 0.0027 T 28-03-2018 CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 PRINTS PR00723 Subtilisin serine protease family (S8) signature 251 264 3.0E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 PRINTS PR00723 Subtilisin serine protease family (S8) signature 414 430 3.0E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 PRINTS PR00723 Subtilisin serine protease family (S8) signature 214 233 3.0E-20 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 219 230 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 255 265 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS21000 baa133d4b0a287250edad934ff3f7185 1066 Gene3D G3DSA:3.40.50.200 175 477 1.3E-86 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS01955 892733574be1f0feb3e51ba879e39bd5 129 Pfam PF04205 FMN-binding domain 58 125 1.8E-7 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CNX65_RS01955 892733574be1f0feb3e51ba879e39bd5 129 SMART SM00900 56 128 2.5E-6 T 28-03-2018 IPR007329 FMN-binding GO:0010181|GO:0016020 CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 139 163 3.1E-5 T 28-03-2018 CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 205 223 3.1E-5 T 28-03-2018 CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 PRINTS PR01036 Tetracycline resistance protein TetB signature 109 129 3.1E-5 T 28-03-2018 CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 13 418 2.5E-89 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 SUPERFAMILY SSF103473 248 454 8.11E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 SUPERFAMILY SSF103473 11 198 8.11E-61 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 Gene3D G3DSA:1.20.1250.20 254 467 3.2E-26 T 28-03-2018 CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 Gene3D G3DSA:1.20.1250.20 8 202 7.0E-30 T 28-03-2018 CNX65_RS13775 a0c33db72acae33759dc6c7c8c03300f 467 Pfam PF07690 Major Facilitator Superfamily 19 409 1.1E-50 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS21490 08b66f8c58396e53d99dfd518facaed1 166 Gene3D G3DSA:1.10.3300.10 1 166 4.6E-35 T 28-03-2018 IPR023286 ABATE domain CNX65_RS21490 08b66f8c58396e53d99dfd518facaed1 166 Pfam PF07336 Putative stress-induced transcription regulator 2 123 3.3E-13 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator CNX65_RS21490 08b66f8c58396e53d99dfd518facaed1 166 SUPERFAMILY SSF160904 2 163 1.57E-36 T 28-03-2018 CNX65_RS21490 08b66f8c58396e53d99dfd518facaed1 166 Pfam PF11706 CGNR zinc finger 121 164 2.0E-20 T 28-03-2018 IPR021005 Zinc finger, CGNR CNX65_RS27065 bb1abdd93dac254fb19d472b985b348c 308 Pfam PF11382 Copper transport outer membrane protein, MctB 1 305 2.5E-95 T 28-03-2018 IPR021522 Copper transporter MctB GO:0006810 CNX65_RS05400 630869167a9b79783c1752b937218125 231 SMART SM00342 147 229 6.4E-7 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS05400 630869167a9b79783c1752b937218125 231 Pfam PF12833 Helix-turn-helix domain 153 224 9.4E-12 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS05400 630869167a9b79783c1752b937218125 231 Gene3D G3DSA:1.10.10.60 109 183 7.5E-5 T 28-03-2018 CNX65_RS05400 630869167a9b79783c1752b937218125 231 Gene3D G3DSA:1.10.10.60 184 229 4.0E-4 T 28-03-2018 CNX65_RS19680 3baa3def0d4c06da56d07cdee4d08e6e 263 SUPERFAMILY SSF53335 92 242 1.45E-10 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS19680 3baa3def0d4c06da56d07cdee4d08e6e 263 Gene3D G3DSA:3.40.50.150 12 262 3.7E-16 T 28-03-2018 CNX65_RS02400 6a5aae688dff23a3aa8c5a12c6f50092 265 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 107 1.3E-24 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CNX65_RS02400 6a5aae688dff23a3aa8c5a12c6f50092 265 PIRSF PIRSF000915 7 258 2.2E-52 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CNX65_RS02400 6a5aae688dff23a3aa8c5a12c6f50092 265 SUPERFAMILY SSF56784 8 254 1.0E-65 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS02400 6a5aae688dff23a3aa8c5a12c6f50092 265 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 229 1.5E-46 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CNX65_RS02400 6a5aae688dff23a3aa8c5a12c6f50092 265 Pfam PF13242 HAD-hyrolase-like 180 253 4.8E-22 T 28-03-2018 CNX65_RS02400 6a5aae688dff23a3aa8c5a12c6f50092 265 Gene3D G3DSA:3.40.50.1000 73 182 3.2E-32 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS13925 8d542499430f887c6dcc25eb5d301cdd 641 Gene3D G3DSA:2.160.20.50 15 83 3.2E-5 T 28-03-2018 CNX65_RS13925 8d542499430f887c6dcc25eb5d301cdd 641 Gene3D G3DSA:3.50.50.60 94 446 1.2E-7 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13925 8d542499430f887c6dcc25eb5d301cdd 641 SUPERFAMILY SSF51905 395 453 9.88E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS13925 8d542499430f887c6dcc25eb5d301cdd 641 SUPERFAMILY SSF51905 101 256 9.88E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS33105 b798ba73c477b59a12385783c0db01af 201 SUPERFAMILY SSF53254 1 186 1.77E-34 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS33105 b798ba73c477b59a12385783c0db01af 201 Gene3D G3DSA:3.40.50.1240 1 191 6.7E-30 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS33105 b798ba73c477b59a12385783c0db01af 201 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 1 181 4.2E-34 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS33105 b798ba73c477b59a12385783c0db01af 201 SMART SM00855 1 149 2.1E-11 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS21685 463c2bef87de7638c0664a27e72c1eeb 427 Gene3D G3DSA:3.40.50.1820 17 411 8.4E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21685 463c2bef87de7638c0664a27e72c1eeb 427 SUPERFAMILY SSF53474 59 88 1.7E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21685 463c2bef87de7638c0664a27e72c1eeb 427 SUPERFAMILY SSF53474 380 402 1.7E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21685 463c2bef87de7638c0664a27e72c1eeb 427 SUPERFAMILY SSF53474 146 331 1.7E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS10720 4ae05b305926e8d72c43863a8fe68326 430 Pfam PF00202 Aminotransferase class-III 25 424 2.0E-84 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS10720 4ae05b305926e8d72c43863a8fe68326 430 SUPERFAMILY SSF53383 16 426 1.73E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS10720 4ae05b305926e8d72c43863a8fe68326 430 Gene3D G3DSA:3.90.1150.10 312 428 2.5E-38 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS10720 4ae05b305926e8d72c43863a8fe68326 430 Gene3D G3DSA:3.90.1150.10 4 168 1.7E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS10720 4ae05b305926e8d72c43863a8fe68326 430 Gene3D G3DSA:3.40.640.10 179 311 3.8E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS10720 4ae05b305926e8d72c43863a8fe68326 430 PIRSF PIRSF000521 124 427 1.1E-35 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS10720 4ae05b305926e8d72c43863a8fe68326 430 PIRSF PIRSF000521 18 130 4.7E-6 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS15685 cd2ef78e678d53dd674d4f914c8982f5 309 SUPERFAMILY SSF103481 46 148 1.96E-11 T 28-03-2018 CNX65_RS15685 cd2ef78e678d53dd674d4f914c8982f5 309 Pfam PF00892 EamA-like transporter family 17 146 3.2E-18 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS15685 cd2ef78e678d53dd674d4f914c8982f5 309 Pfam PF00892 EamA-like transporter family 159 293 2.3E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS15685 cd2ef78e678d53dd674d4f914c8982f5 309 SUPERFAMILY SSF103481 198 296 3.79E-13 T 28-03-2018 CNX65_RS20640 0ff76f814a07f91ca7583993a691f5a2 418 Gene3D G3DSA:3.50.30.10 10 98 1.1E-9 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CNX65_RS20640 0ff76f814a07f91ca7583993a691f5a2 418 Gene3D G3DSA:3.20.20.60 158 403 1.2E-29 T 28-03-2018 CNX65_RS20640 0ff76f814a07f91ca7583993a691f5a2 418 Pfam PF00391 PEP-utilising enzyme, mobile domain 23 76 9.2E-9 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CNX65_RS20640 0ff76f814a07f91ca7583993a691f5a2 418 SUPERFAMILY SSF51621 165 374 4.19E-28 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS20640 0ff76f814a07f91ca7583993a691f5a2 418 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 181 360 4.2E-19 T 28-03-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 CNX65_RS20640 0ff76f814a07f91ca7583993a691f5a2 418 SUPERFAMILY SSF52009 23 73 1.18E-8 T 28-03-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 CNX65_RS05960 5f20e219bb2e5e5e9e9fcba55220fbb1 73 SUPERFAMILY SSF54862 5 61 7.33E-10 T 28-03-2018 CNX65_RS05960 5f20e219bb2e5e5e9e9fcba55220fbb1 73 Pfam PF13459 4Fe-4S single cluster domain 6 61 1.6E-12 T 28-03-2018 CNX65_RS05960 5f20e219bb2e5e5e9e9fcba55220fbb1 73 Gene3D G3DSA:3.30.70.20 19 70 8.3E-4 T 28-03-2018 CNX65_RS05960 5f20e219bb2e5e5e9e9fcba55220fbb1 73 Gene3D G3DSA:3.30.70.20 3 18 0.11 T 28-03-2018 CNX65_RS05960 5f20e219bb2e5e5e9e9fcba55220fbb1 73 PRINTS PR00352 3Fe-4S ferredoxin signature 8 19 3.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS05960 5f20e219bb2e5e5e9e9fcba55220fbb1 73 PRINTS PR00352 3Fe-4S ferredoxin signature 19 29 3.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS05960 5f20e219bb2e5e5e9e9fcba55220fbb1 73 PRINTS PR00352 3Fe-4S ferredoxin signature 47 59 3.2E-7 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS23375 c26646762c9fc8047bd22ce5c346bf26 517 Gene3D G3DSA:3.40.640.10 62 377 3.7E-54 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS23375 c26646762c9fc8047bd22ce5c346bf26 517 Gene3D G3DSA:3.90.1150.10 378 509 3.2E-22 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS23375 c26646762c9fc8047bd22ce5c346bf26 517 SUPERFAMILY SSF53383 193 506 8.15E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS23375 c26646762c9fc8047bd22ce5c346bf26 517 SUPERFAMILY SSF53383 27 133 8.15E-71 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS23375 c26646762c9fc8047bd22ce5c346bf26 517 PIRSF PIRSF000521 16 152 4.3E-4 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS23375 c26646762c9fc8047bd22ce5c346bf26 517 PIRSF PIRSF000521 172 509 1.4E-23 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS23375 c26646762c9fc8047bd22ce5c346bf26 517 Pfam PF00202 Aminotransferase class-III 25 504 4.3E-58 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 SMART SM00729 76 309 1.1E-13 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 Gene3D G3DSA:3.20.20.70 14 382 3.7E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 Gene3D G3DSA:3.20.20.70 466 836 2.1E-46 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 Hamap MF_01612 FO synthase subunit 2 [cofH]. 469 835 47.633 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 73 398 7.1E-146 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 SUPERFAMILY SSF102114 496 798 8.11E-45 T 28-03-2018 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 494 834 4.8E-151 T 28-03-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 SUPERFAMILY SSF102114 36 374 1.31E-40 T 28-03-2018 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 524 831 5.3E-106 T 28-03-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 Hamap MF_01611 FO synthase subunit 1 [cofG]. 72 400 50.715 T 28-03-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77|MetaCyc: PWY-5198 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 Pfam PF04055 Radical SAM superfamily 80 257 1.5E-10 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS31755 fb629892e513abf5d9b37ebedd253235 838 Pfam PF04055 Radical SAM superfamily 532 692 9.6E-13 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS30650 49053745e291605e56bc64a225e21178 253 Gene3D G3DSA:3.90.226.10 1 245 8.8E-62 T 28-03-2018 CNX65_RS30650 49053745e291605e56bc64a225e21178 253 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 95 115 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CNX65_RS30650 49053745e291605e56bc64a225e21178 253 SUPERFAMILY SSF52096 2 245 1.91E-64 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS30650 49053745e291605e56bc64a225e21178 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 243 4.8E-42 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS03230 85ef41e2924d11f85d7742acfcf7df57 546 SUPERFAMILY SSF56801 26 543 3.14E-83 T 28-03-2018 CNX65_RS03230 85ef41e2924d11f85d7742acfcf7df57 546 Gene3D G3DSA:3.40.50.980 2 165 1.7E-19 T 28-03-2018 CNX65_RS03230 85ef41e2924d11f85d7742acfcf7df57 546 Pfam PF00501 AMP-binding enzyme 30 443 4.7E-60 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS03230 85ef41e2924d11f85d7742acfcf7df57 546 Gene3D G3DSA:2.30.38.10 363 436 3.9E-11 T 28-03-2018 CNX65_RS03230 85ef41e2924d11f85d7742acfcf7df57 546 Pfam PF14535 AMP-binding enzyme C-terminal domain 445 537 2.7E-6 T 28-03-2018 IPR028154 AMP-dependent ligase, C-terminal CNX65_RS03230 85ef41e2924d11f85d7742acfcf7df57 546 Gene3D G3DSA:3.30.300.30 437 542 7.3E-15 T 28-03-2018 CNX65_RS03230 85ef41e2924d11f85d7742acfcf7df57 546 Gene3D G3DSA:3.40.50.980 166 338 6.9E-30 T 28-03-2018 CNX65_RS03155 b5328272a0c9d9af66fb8f2620e29043 281 PIRSF PIRSF005917 3 281 7.4E-89 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS03155 b5328272a0c9d9af66fb8f2620e29043 281 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 212 8.7E-28 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS03155 b5328272a0c9d9af66fb8f2620e29043 281 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 9 229 32.47 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS03155 b5328272a0c9d9af66fb8f2620e29043 281 Gene3D G3DSA:3.30.950.10 120 232 6.2E-44 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS03155 b5328272a0c9d9af66fb8f2620e29043 281 Gene3D G3DSA:3.40.1010.10 7 119 7.9E-30 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS03155 b5328272a0c9d9af66fb8f2620e29043 281 SUPERFAMILY SSF53790 8 227 3.27E-71 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS03155 b5328272a0c9d9af66fb8f2620e29043 281 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 10 277 2.3E-64 T 28-03-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS01535 0416d9e4a57a85f2436e6e134f85a270 329 Gene3D G3DSA:3.40.50.1980 164 328 1.1E-25 T 28-03-2018 CNX65_RS01535 0416d9e4a57a85f2436e6e134f85a270 329 Pfam PF01497 Periplasmic binding protein 63 303 2.4E-27 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS01535 0416d9e4a57a85f2436e6e134f85a270 329 SUPERFAMILY SSF53807 44 324 8.24E-50 T 28-03-2018 CNX65_RS01535 0416d9e4a57a85f2436e6e134f85a270 329 Gene3D G3DSA:3.40.50.1980 42 163 1.2E-30 T 28-03-2018 CNX65_RS26200 148970b821a845118266be931ec8e605 170 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 15 152 22.764 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CNX65_RS26200 148970b821a845118266be931ec8e605 170 Gene3D G3DSA:3.30.420.140 14 162 4.8E-44 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CNX65_RS26200 148970b821a845118266be931ec8e605 170 SMART SM00732 15 117 8.8E-23 T 28-03-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 CNX65_RS26200 148970b821a845118266be931ec8e605 170 SUPERFAMILY SSF53098 15 150 1.44E-34 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS26200 148970b821a845118266be931ec8e605 170 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 18 149 4.6E-28 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CNX65_RS26200 148970b821a845118266be931ec8e605 170 Pfam PF03652 Holliday junction resolvase 16 149 5.3E-42 T 28-03-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 SMART SM00895 95 221 6.4E-15 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 Gene3D G3DSA:1.20.120.530 74 232 6.4E-24 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 Pfam PF00392 Bacterial regulatory proteins, gntR family 7 63 6.8E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 Gene3D G3DSA:1.10.10.10 2 73 1.2E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 SUPERFAMILY SSF46785 7 63 5.69E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 SMART SM00345 7 70 4.4E-12 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 Pfam PF07729 FCD domain 96 220 2.2E-18 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 SUPERFAMILY SSF48008 93 226 3.92E-19 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 26 40 5.0E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS15425 30184c14ce8f6ef598bde257ab584385 232 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 40 56 5.0E-10 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS11680 cfa827fa73765f0d50ff324f0fbe9a02 209 Gene3D G3DSA:3.40.50.150 5 207 5.4E-33 T 28-03-2018 CNX65_RS11680 cfa827fa73765f0d50ff324f0fbe9a02 209 SUPERFAMILY SSF53335 10 195 3.05E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS11680 cfa827fa73765f0d50ff324f0fbe9a02 209 Pfam PF13649 Methyltransferase domain 49 139 7.1E-21 T 28-03-2018 CNX65_RS03400 e1afa5bd4b45e469df6551d010d59db9 223 Pfam PF13559 Domain of unknown function (DUF4129) 142 211 1.1E-9 T 28-03-2018 IPR025403 Domain of unknown function DUF4129 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 Pfam PF01494 FAD binding domain 5 343 4.3E-25 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 SUPERFAMILY SSF51905 5 172 3.89E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 SUPERFAMILY SSF51905 270 366 3.89E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 4.5E-14 T 28-03-2018 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 283 298 4.5E-14 T 28-03-2018 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 151 166 4.5E-14 T 28-03-2018 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 298 314 4.5E-14 T 28-03-2018 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 SUPERFAMILY SSF54373 177 276 2.16E-12 T 28-03-2018 CNX65_RS15960 2c84344bd6edf3d2ef27bac4ab63c6b5 400 Gene3D G3DSA:3.50.50.60 2 391 9.7E-47 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23185 650337db716d165f3fd1e65107ddb667 416 Gene3D G3DSA:1.20.1250.20 12 204 1.9E-13 T 28-03-2018 CNX65_RS23185 650337db716d165f3fd1e65107ddb667 416 SUPERFAMILY SSF103473 14 398 7.59E-44 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23185 650337db716d165f3fd1e65107ddb667 416 Gene3D G3DSA:1.20.1250.20 210 402 6.2E-21 T 28-03-2018 CNX65_RS23185 650337db716d165f3fd1e65107ddb667 416 Pfam PF07690 Major Facilitator Superfamily 23 247 3.5E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS02135 4c2e76bc317c5d7e1efef4e2ea7464b1 189 Gene3D G3DSA:1.10.10.60 2 58 8.8E-17 T 28-03-2018 CNX65_RS02135 4c2e76bc317c5d7e1efef4e2ea7464b1 189 SUPERFAMILY SSF48498 81 179 8.09E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS02135 4c2e76bc317c5d7e1efef4e2ea7464b1 189 Gene3D G3DSA:1.10.357.10 59 186 1.5E-23 T 28-03-2018 CNX65_RS02135 4c2e76bc317c5d7e1efef4e2ea7464b1 189 SUPERFAMILY SSF46689 6 77 1.7E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS02135 4c2e76bc317c5d7e1efef4e2ea7464b1 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02135 4c2e76bc317c5d7e1efef4e2ea7464b1 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.2E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02135 4c2e76bc317c5d7e1efef4e2ea7464b1 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 8.4E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13995 6ad003a07f377ba251eaa5000e4c0c13 142 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 8 92 1.0E-10 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS13995 6ad003a07f377ba251eaa5000e4c0c13 142 SUPERFAMILY SSF50475 8 140 1.18E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS13995 6ad003a07f377ba251eaa5000e4c0c13 142 Gene3D G3DSA:2.30.110.10 1 141 1.0E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS09265 ae8925c4d115e14af1e7248ed044a332 327 SUPERFAMILY SSF53822 39 318 1.62E-70 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09265 ae8925c4d115e14af1e7248ed044a332 327 Pfam PF13407 Periplasmic binding protein domain 48 301 4.3E-45 T 28-03-2018 IPR025997 Periplasmic binding protein CNX65_RS09265 ae8925c4d115e14af1e7248ed044a332 327 Gene3D G3DSA:3.40.50.2300 42 148 4.3E-18 T 28-03-2018 CNX65_RS09265 ae8925c4d115e14af1e7248ed044a332 327 Gene3D G3DSA:3.40.50.2300 149 327 2.7E-38 T 28-03-2018 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 185 200 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 71 86 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 96 108 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 298 325 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 344 361 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 21 45 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 361 374 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PRINTS PR00370 Flavin-containing monooxygenase (FMO) signature 129 145 1.9E-28 T 28-03-2018 IPR000960 Flavin monooxygenase FMO GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 Gene3D G3DSA:3.50.50.60 1 185 2.2E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 Pfam PF00743 Flavin-binding monooxygenase-like 1 422 6.0E-77 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 SUPERFAMILY SSF51905 1 204 7.45E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 SUPERFAMILY SSF51905 258 422 6.98E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 Gene3D G3DSA:3.50.50.60 186 431 6.8E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10575 d1c125457f8272aa63f256e493bedfce 432 PIRSF PIRSF000332 1 429 2.2E-88 T 28-03-2018 CNX65_RS17180 be9d79b12cab73d63f6b0278a417aed4 183 Pfam PF13302 Acetyltransferase (GNAT) domain 16 148 4.6E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS17180 be9d79b12cab73d63f6b0278a417aed4 183 Gene3D G3DSA:3.40.630.30 9 183 1.8E-24 T 28-03-2018 CNX65_RS17180 be9d79b12cab73d63f6b0278a417aed4 183 SUPERFAMILY SSF55729 7 177 9.33E-32 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS22310 9dacd69373e409e60d56af956ed20807 385 Pfam PF00480 ROK family 83 377 2.7E-43 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS22310 9dacd69373e409e60d56af956ed20807 385 SUPERFAMILY SSF46785 8 72 9.23E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22310 9dacd69373e409e60d56af956ed20807 385 Gene3D G3DSA:3.30.420.40 75 198 1.7E-27 T 28-03-2018 CNX65_RS22310 9dacd69373e409e60d56af956ed20807 385 Gene3D G3DSA:3.30.420.40 199 384 2.5E-42 T 28-03-2018 CNX65_RS22310 9dacd69373e409e60d56af956ed20807 385 Gene3D G3DSA:1.10.10.10 6 74 1.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22310 9dacd69373e409e60d56af956ed20807 385 SUPERFAMILY SSF53067 82 380 1.95E-42 T 28-03-2018 CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 SUPERFAMILY SSF51445 189 560 1.51E-81 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 Gene3D G3DSA:1.20.58.280 101 174 7.5E-20 T 28-03-2018 CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 Gene3D G3DSA:2.60.40.10 1 100 1.2E-41 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 Pfam PF11896 Domain of unknown function (DUF3416) 3 193 5.7E-59 T 28-03-2018 IPR021828 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase, domain N/S GO:0004553 KEGG: 00500+2.4.99.16 CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 Gene3D G3DSA:3.20.20.80 195 563 3.4E-62 T 28-03-2018 CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 SMART SM00642 199 553 6.7E-4 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 Hamap MF_02124 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase [glgE]. 1 655 44.972 T 28-03-2018 IPR026585 Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase GO:0016757 KEGG: 00500+2.4.99.16 CNX65_RS29885 f426eaf8bcb9008ddcb1aa3066f49cf8 659 Gene3D G3DSA:2.60.40.1180 564 658 2.4E-34 T 28-03-2018 CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 SMART SM00895 87 209 2.4E-12 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 Gene3D G3DSA:1.20.120.530 80 217 5.1E-26 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 SUPERFAMILY SSF48008 83 212 3.4E-20 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 Gene3D G3DSA:1.10.10.10 1 79 2.7E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 Pfam PF07729 FCD domain 91 208 7.1E-20 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 SUPERFAMILY SSF46785 9 81 3.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 Pfam PF00392 Bacterial regulatory proteins, gntR family 15 77 8.3E-17 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS02180 754c16b497d1ae9c172dff11dba868eb 235 SMART SM00345 19 77 6.0E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 Gene3D G3DSA:3.40.50.300 698 951 1.4E-74 T 28-03-2018 CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 Gene3D G3DSA:1.20.1560.10 369 696 4.9E-33 T 28-03-2018 CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 Gene3D G3DSA:3.30.70.100 41 95 9.8E-5 T 28-03-2018 CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 ProSitePatterns PS00211 ABC transporters family signature. 847 861 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 SUPERFAMILY SSF90123 372 695 9.16E-38 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 Pfam PF00005 ABC transporter 726 875 2.0E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 SMART SM00382 735 921 5.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 SUPERFAMILY SSF52540 703 946 4.28E-86 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18235 024a7491f238d4eb1a7b696d3f7ebe11 951 Pfam PF00664 ABC transporter transmembrane region 430 651 1.6E-11 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS30800 b6afe26fd5251b0a5ebaa6f9bfb2f939 330 SUPERFAMILY SSF51430 1 313 1.83E-94 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS30800 b6afe26fd5251b0a5ebaa6f9bfb2f939 330 Gene3D G3DSA:3.20.20.100 1 322 2.4E-90 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS30800 b6afe26fd5251b0a5ebaa6f9bfb2f939 330 Pfam PF00248 Aldo/keto reductase family 15 312 2.6E-71 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS20720 ffe82f949b4d93dd21d717a19eef8408 279 SUPERFAMILY SSF53300 13 187 9.15E-14 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS20720 ffe82f949b4d93dd21d717a19eef8408 279 Gene3D G3DSA:3.40.50.410 8 271 2.4E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS20720 ffe82f949b4d93dd21d717a19eef8408 279 SMART SM00327 12 227 3.1E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS23640 837839080aba10f79998a53850f5e371 824 SMART SM00631 246 542 8.3E-36 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS23640 837839080aba10f79998a53850f5e371 824 Gene3D G3DSA:3.40.630.10 243 543 4.5E-51 T 28-03-2018 CNX65_RS23640 837839080aba10f79998a53850f5e371 824 Pfam PF00246 Zinc carboxypeptidase 256 532 2.4E-43 T 28-03-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 CNX65_RS23640 837839080aba10f79998a53850f5e371 824 Gene3D G3DSA:2.60.120.380 672 773 5.9E-9 T 28-03-2018 CNX65_RS23640 837839080aba10f79998a53850f5e371 824 SUPERFAMILY SSF53187 244 533 1.92E-50 T 28-03-2018 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 Gene3D G3DSA:2.40.10.10 43 71 1.3E-10 T 28-03-2018 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 Gene3D G3DSA:2.40.10.10 127 249 8.6E-13 T 28-03-2018 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 SUPERFAMILY SSF50494 32 248 2.43E-37 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 196 208 8.5E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 113 127 8.5E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 67 82 8.5E-7 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 Gene3D G3DSA:2.40.10.10 72 126 4.5E-15 T 28-03-2018 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 Pfam PF00089 Trypsin 49 244 5.8E-23 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS30960 5a6a0be0aeaa388d932fa0f78bb5e146 250 SMART SM00020 42 244 8.4E-12 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS33195 115b0c067d7fd325ecaab5f23b32165a 217 SUPERFAMILY SSF88659 150 212 2.8E-14 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS33195 115b0c067d7fd325ecaab5f23b32165a 217 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 53 211 2.2E-28 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS33195 115b0c067d7fd325ecaab5f23b32165a 217 Gene3D G3DSA:1.10.10.10 131 215 5.1E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33195 115b0c067d7fd325ecaab5f23b32165a 217 SUPERFAMILY SSF88946 38 141 1.8E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS33195 115b0c067d7fd325ecaab5f23b32165a 217 Gene3D G3DSA:1.10.1740.10 36 130 2.3E-21 T 28-03-2018 CNX65_RS33195 115b0c067d7fd325ecaab5f23b32165a 217 Pfam PF04542 Sigma-70 region 2 58 125 5.3E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS33195 115b0c067d7fd325ecaab5f23b32165a 217 Pfam PF08281 Sigma-70, region 4 156 208 1.2E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS23610 79c00d10886a071febc98161033204dd 213 SUPERFAMILY SSF55729 19 159 2.06E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS23610 79c00d10886a071febc98161033204dd 213 Gene3D G3DSA:3.40.630.30 9 169 9.3E-15 T 28-03-2018 CNX65_RS23610 79c00d10886a071febc98161033204dd 213 Pfam PF00583 Acetyltransferase (GNAT) family 26 139 4.7E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS33555 1082d1d1fd42de625c6bb78d25d6b780 668 SUPERFAMILY SSF117892 57 200 1.44E-9 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS31625 d34fbd143bfadd1b6e4b73f25d1be8cf 408 SUPERFAMILY SSF58113 141 272 4.97E-10 T 28-03-2018 CNX65_RS31625 d34fbd143bfadd1b6e4b73f25d1be8cf 408 Gene3D G3DSA:1.10.287.850 203 275 0.0071 T 28-03-2018 CNX65_RS31625 d34fbd143bfadd1b6e4b73f25d1be8cf 408 Gene3D G3DSA:3.90.20.10 91 202 5.2E-21 T 28-03-2018 CNX65_RS31625 d34fbd143bfadd1b6e4b73f25d1be8cf 408 Gene3D G3DSA:1.20.5.30 276 296 0.0026 T 28-03-2018 CNX65_RS31625 d34fbd143bfadd1b6e4b73f25d1be8cf 408 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 84 318 0.008 T 28-03-2018 CNX65_RS31625 d34fbd143bfadd1b6e4b73f25d1be8cf 408 Gene3D G3DSA:1.20.5.110 297 349 0.02 T 28-03-2018 CNX65_RS31625 d34fbd143bfadd1b6e4b73f25d1be8cf 408 Gene3D G3DSA:1.20.5.1070 12 90 0.025 T 28-03-2018 CNX65_RS08585 b357512bbd07dddc014f1dc25bc0a6f7 422 Pfam PF00535 Glycosyl transferase family 2 19 186 1.5E-20 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS08585 b357512bbd07dddc014f1dc25bc0a6f7 422 SUPERFAMILY SSF53448 6 227 2.53E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08585 b357512bbd07dddc014f1dc25bc0a6f7 422 Gene3D G3DSA:3.90.550.10 2 248 4.8E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08585 b357512bbd07dddc014f1dc25bc0a6f7 422 Pfam PF04138 GtrA-like protein 283 400 3.6E-12 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 Gene3D G3DSA:3.40.50.150 78 288 3.3E-46 T 28-03-2018 CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 Gene3D G3DSA:1.10.8.10 2 77 1.3E-15 T 28-03-2018 CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 SUPERFAMILY SSF53335 10 283 1.43E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 6 286 40.692 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 28 282 1.2E-73 T 28-03-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 191 197 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 23 285 1.6E-44 T 28-03-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 CNX65_RS30255 c247de4fcea87929b51112669a4542af 288 Pfam PF05175 Methyltransferase small domain 106 201 7.3E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CNX65_RS19150 8face409cb26fa9e3ab378b22a47ed36 442 SUPERFAMILY SSF51905 398 435 1.29E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19150 8face409cb26fa9e3ab378b22a47ed36 442 SUPERFAMILY SSF51905 14 295 1.29E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19150 8face409cb26fa9e3ab378b22a47ed36 442 Gene3D G3DSA:3.90.660.20 48 385 1.1E-39 T 28-03-2018 CNX65_RS19150 8face409cb26fa9e3ab378b22a47ed36 442 SUPERFAMILY SSF54373 281 385 5.1E-10 T 28-03-2018 CNX65_RS19150 8face409cb26fa9e3ab378b22a47ed36 442 Pfam PF01593 Flavin containing amine oxidoreductase 25 431 3.3E-39 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS14995 879e16fa6ad351477622496c007891e8 271 Pfam PF13560 Helix-turn-helix domain 4 82 2.5E-15 T 28-03-2018 CNX65_RS14995 879e16fa6ad351477622496c007891e8 271 SUPERFAMILY SSF47413 27 75 2.64E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS14995 879e16fa6ad351477622496c007891e8 271 SMART SM00530 8 80 1.6E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS14995 879e16fa6ad351477622496c007891e8 271 Gene3D G3DSA:1.10.260.40 1 85 1.7E-15 T 28-03-2018 CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 Gene3D G3DSA:3.40.640.10 181 314 1.5E-40 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 6 422 1.8E-179 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 Gene3D G3DSA:3.90.1150.10 1 180 8.8E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 Pfam PF00202 Aminotransferase class-III 35 418 3.0E-84 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 SUPERFAMILY SSF53383 4 422 9.6E-117 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 Gene3D G3DSA:3.90.1150.10 315 428 5.8E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 426 96.275 T 28-03-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 CNX65_RS33110 35efdc7b28d09e60537804bd7868198e 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 236 272 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS07250 2b58de5eaa0d5d6dc0655fd10789d79e 320 Gene3D G3DSA:3.90.25.10 168 320 4.1E-39 T 28-03-2018 CNX65_RS07250 2b58de5eaa0d5d6dc0655fd10789d79e 320 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 246 5.7E-58 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS07250 2b58de5eaa0d5d6dc0655fd10789d79e 320 SUPERFAMILY SSF51735 2 316 2.94E-89 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07250 2b58de5eaa0d5d6dc0655fd10789d79e 320 Gene3D G3DSA:3.40.50.720 2 167 1.2E-32 T 28-03-2018 CNX65_RS07250 2b58de5eaa0d5d6dc0655fd10789d79e 320 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 2 317 5.1E-114 T 28-03-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-70370 CNX65_RS15510 9d2b2016cfbaa46d367464687ebd423f 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 3.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS15510 9d2b2016cfbaa46d367464687ebd423f 189 SUPERFAMILY SSF48498 79 184 2.31E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS15510 9d2b2016cfbaa46d367464687ebd423f 189 Gene3D G3DSA:1.10.10.60 1 61 2.4E-19 T 28-03-2018 CNX65_RS15510 9d2b2016cfbaa46d367464687ebd423f 189 SUPERFAMILY SSF46689 3 65 2.0E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS15510 9d2b2016cfbaa46d367464687ebd423f 189 Gene3D G3DSA:1.10.357.10 62 185 3.6E-21 T 28-03-2018 CNX65_RS15510 9d2b2016cfbaa46d367464687ebd423f 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS15510 9d2b2016cfbaa46d367464687ebd423f 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.8E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS31505 dc3ede0f5ea57d80a676bb32f500c023 598 Gene3D G3DSA:1.10.510.10 82 414 6.5E-49 T 28-03-2018 CNX65_RS31505 dc3ede0f5ea57d80a676bb32f500c023 598 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS31505 dc3ede0f5ea57d80a676bb32f500c023 598 SMART SM00220 11 269 4.9E-59 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS31505 dc3ede0f5ea57d80a676bb32f500c023 598 Gene3D G3DSA:3.30.200.20 1 81 3.3E-18 T 28-03-2018 CNX65_RS31505 dc3ede0f5ea57d80a676bb32f500c023 598 SUPERFAMILY SSF56112 5 267 2.16E-68 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS31505 dc3ede0f5ea57d80a676bb32f500c023 598 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS31505 dc3ede0f5ea57d80a676bb32f500c023 598 Pfam PF00069 Protein kinase domain 11 260 1.7E-46 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS12250 02e5de21ed33ab999d6306d58e3c5eb6 133 SUPERFAMILY SSF160424 3 128 2.75E-18 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS29145 ffd51b2b867bb14b441d9f5fc3873a3f 490 Pfam PF01979 Amidohydrolase family 104 472 1.4E-27 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS29145 ffd51b2b867bb14b441d9f5fc3873a3f 490 Gene3D G3DSA:3.20.20.140 123 439 7.2E-114 T 28-03-2018 CNX65_RS29145 ffd51b2b867bb14b441d9f5fc3873a3f 490 Gene3D G3DSA:2.30.40.10 2 122 3.4E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS29145 ffd51b2b867bb14b441d9f5fc3873a3f 490 SUPERFAMILY SSF51338 1 40 5.1E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS29145 ffd51b2b867bb14b441d9f5fc3873a3f 490 SUPERFAMILY SSF51338 419 476 5.1E-19 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS29145 ffd51b2b867bb14b441d9f5fc3873a3f 490 SUPERFAMILY SSF51556 108 420 1.11E-95 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS29145 ffd51b2b867bb14b441d9f5fc3873a3f 490 TIGRFAM TIGR03178 allantoinase: allantoinase 84 478 1.1E-157 T 28-03-2018 IPR017593 Allantoinase GO:0000256|GO:0004038|GO:0008270|GO:0050897 KEGG: 00230+3.5.2.5|MetaCyc: PWY-5697|MetaCyc: PWY-5698 CNX65_RS17795 e68e61426ca616a40f9d7d8495170e85 161 Pfam PF12802 MarR family 50 109 5.8E-10 T 28-03-2018 CNX65_RS17795 e68e61426ca616a40f9d7d8495170e85 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 106 122 2.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS17795 e68e61426ca616a40f9d7d8495170e85 161 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 102 2.5E-6 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS17795 e68e61426ca616a40f9d7d8495170e85 161 SMART SM00347 43 146 1.8E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS17795 e68e61426ca616a40f9d7d8495170e85 161 SUPERFAMILY SSF46785 10 159 6.82E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17795 e68e61426ca616a40f9d7d8495170e85 161 Gene3D G3DSA:1.10.10.10 2 161 2.8E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17400 877d612c99c58f0016e53593f574cb57 296 Gene3D G3DSA:2.160.20.80 108 292 3.1E-16 T 28-03-2018 CNX65_RS17400 877d612c99c58f0016e53593f574cb57 296 Pfam PF13576 Pentapeptide repeats (9 copies) 154 200 7.0E-9 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS17400 877d612c99c58f0016e53593f574cb57 296 Pfam PF13576 Pentapeptide repeats (9 copies) 220 266 2.3E-8 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS17400 877d612c99c58f0016e53593f574cb57 296 SUPERFAMILY SSF141571 134 247 2.35E-6 T 28-03-2018 CNX65_RS31075 a85e55841521a1a50c6ef0cfed4c4952 576 Pfam PF10646 Sporulation and spore germination 173 284 5.9E-8 T 28-03-2018 IPR019606 GerMN domain CNX65_RS31075 a85e55841521a1a50c6ef0cfed4c4952 576 Gene3D G3DSA:2.130.10.10 263 544 4.9E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS31075 a85e55841521a1a50c6ef0cfed4c4952 576 SMART SM00909 200 288 6.7E-6 T 28-03-2018 IPR019606 GerMN domain CNX65_RS31075 a85e55841521a1a50c6ef0cfed4c4952 576 Pfam PF10647 Lipoprotein LpqB beta-propeller domain 325 561 1.3E-43 T 28-03-2018 IPR018910 Lipoprotein LpqB, beta-propeller domain, C-terminal CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 19 32 8.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 39 62 8.5E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 Gene3D G3DSA:1.10.357.10 72 197 9.6E-12 T 28-03-2018 CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 Gene3D G3DSA:1.10.10.60 1 40 2.9E-14 T 28-03-2018 CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 SUPERFAMILY SSF46689 6 88 1.4E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 Gene3D G3DSA:1.10.260.40 41 71 2.3E-10 T 28-03-2018 CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 SUPERFAMILY SSF48498 84 190 9.71E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS28385 735120578f1791ba868e855cf78bc842 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 64 3.9E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Gene3D G3DSA:3.40.120.10 334 439 1.6E-30 T 28-03-2018 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 SUPERFAMILY SSF55957 440 512 3.14E-10 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Gene3D G3DSA:3.40.120.10 20 213 1.7E-55 T 28-03-2018 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Gene3D G3DSA:3.30.310.50 441 541 2.1E-14 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 481 522 6.3E-9 T 28-03-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 150 159 - T 28-03-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 54 189 2.7E-38 T 28-03-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 SUPERFAMILY SSF53738 42 234 1.49E-42 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 227 246 7.2E-9 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 149 163 7.2E-9 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 294 309 7.2E-9 T 28-03-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 SUPERFAMILY SSF53738 302 438 1.61E-25 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 323 431 7.7E-16 T 28-03-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 SUPERFAMILY SSF53738 211 309 1.18E-21 T 28-03-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 223 309 5.1E-23 T 28-03-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 CNX65_RS31515 963ed8c805f5e0746e4e299e35ca2291 542 Gene3D G3DSA:3.40.120.10 214 333 5.9E-27 T 28-03-2018 CNX65_RS23545 6baf3ecefc0a9524103b568f10a7b04f 490 Gene3D G3DSA:2.30.40.10 381 457 8.7E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS23545 6baf3ecefc0a9524103b568f10a7b04f 490 Pfam PF01979 Amidohydrolase family 72 450 6.0E-23 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS23545 6baf3ecefc0a9524103b568f10a7b04f 490 SUPERFAMILY SSF51556 75 403 5.79E-43 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS23545 6baf3ecefc0a9524103b568f10a7b04f 490 Gene3D G3DSA:3.20.20.140 87 380 1.1E-30 T 28-03-2018 CNX65_RS23545 6baf3ecefc0a9524103b568f10a7b04f 490 Gene3D G3DSA:2.30.40.10 8 86 3.2E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS23545 6baf3ecefc0a9524103b568f10a7b04f 490 SUPERFAMILY SSF51338 22 75 2.32E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS23545 6baf3ecefc0a9524103b568f10a7b04f 490 SUPERFAMILY SSF51338 402 476 2.32E-24 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS06595 39fb1edceb3a4a22446cd47346b6a7fc 152 SUPERFAMILY SSF52833 1 151 5.95E-48 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS06595 39fb1edceb3a4a22446cd47346b6a7fc 152 Gene3D G3DSA:3.40.30.10 1 151 4.5E-41 T 28-03-2018 CNX65_RS06595 39fb1edceb3a4a22446cd47346b6a7fc 152 PIRSF PIRSF000239 1 150 1.4E-25 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS06595 39fb1edceb3a4a22446cd47346b6a7fc 152 Pfam PF00578 AhpC/TSA family 4 129 2.3E-38 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS21835 329b289388e1ba1b4d709934347c42ea 430 Gene3D G3DSA:3.40.50.2000 230 392 9.7E-26 T 28-03-2018 CNX65_RS21835 329b289388e1ba1b4d709934347c42ea 430 Pfam PF06722 Protein of unknown function (DUF1205) 203 295 5.5E-9 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 CNX65_RS21835 329b289388e1ba1b4d709934347c42ea 430 Gene3D G3DSA:3.40.50.2000 1 229 1.2E-24 T 28-03-2018 CNX65_RS21835 329b289388e1ba1b4d709934347c42ea 430 SUPERFAMILY SSF53756 2 56 8.64E-57 T 28-03-2018 CNX65_RS21835 329b289388e1ba1b4d709934347c42ea 430 SUPERFAMILY SSF53756 101 408 8.64E-57 T 28-03-2018 CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 SUPERFAMILY SSF52540 117 242 1.25E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 SUPERFAMILY SSF52540 7 71 1.25E-12 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 Gene3D G3DSA:1.10.10.10 898 963 5.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 Gene3D G3DSA:1.25.40.10 392 632 5.4E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 Gene3D G3DSA:1.25.40.10 645 897 0.031 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 Pfam PF13191 AAA ATPase domain 8 173 5.2E-20 T 28-03-2018 CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 SUPERFAMILY SSF46894 902 961 7.82E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 Pfam PF00196 Bacterial regulatory proteins, luxR family 907 947 6.2E-7 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 SMART SM00421 903 960 2.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26460 3e7ee8bc3e156078a7e7a327ff3e5f11 965 Gene3D G3DSA:3.40.50.300 8 239 7.1E-12 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 SUPERFAMILY SSF48452 664 753 2.3E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Gene3D G3DSA:1.25.40.10 595 656 3.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Gene3D G3DSA:3.40.50.300 44 200 2.0E-15 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 SUPERFAMILY SSF52540 43 316 1.71E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Gene3D G3DSA:3.40.47.10 316 473 3.2E-4 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 PRINTS PR00364 Disease resistance protein signature 159 173 4.1E-8 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 PRINTS PR00364 Disease resistance protein signature 81 96 4.1E-8 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 PRINTS PR00364 Disease resistance protein signature 247 261 4.1E-8 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Pfam PF13424 Tetratricopeptide repeat 587 655 6.2E-10 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Gene3D G3DSA:1.10.150.200 657 712 3.1E-5 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Gene3D G3DSA:1.10.150.200 549 594 0.0029 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 SUPERFAMILY SSF48452 491 659 1.26E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Gene3D G3DSA:3.30.70.100 713 753 3.0E-4 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Gene3D G3DSA:3.30.70.100 483 548 4.8E-5 T 28-03-2018 CNX65_RS30815 5ebd61e7158d4ddd6396c725da89c7b6 788 Pfam PF00931 NB-ARC domain 70 260 2.1E-6 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS14030 9bb7d42b20e8f5306da1bd3ab97a0bf7 192 Pfam PF08281 Sigma-70, region 4 129 178 3.8E-13 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14030 9bb7d42b20e8f5306da1bd3ab97a0bf7 192 Gene3D G3DSA:1.10.1740.10 6 96 1.7E-19 T 28-03-2018 CNX65_RS14030 9bb7d42b20e8f5306da1bd3ab97a0bf7 192 SUPERFAMILY SSF88946 10 108 4.19E-21 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14030 9bb7d42b20e8f5306da1bd3ab97a0bf7 192 SUPERFAMILY SSF88659 124 181 1.02E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14030 9bb7d42b20e8f5306da1bd3ab97a0bf7 192 Pfam PF04542 Sigma-70 region 2 36 99 8.7E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14030 9bb7d42b20e8f5306da1bd3ab97a0bf7 192 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 30 181 7.2E-22 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14030 9bb7d42b20e8f5306da1bd3ab97a0bf7 192 Gene3D G3DSA:1.10.10.10 128 189 2.4E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11185 669db093832fd05f40334c3929ac155f 652 Gene3D G3DSA:3.40.50.410 458 623 1.3E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS11185 669db093832fd05f40334c3929ac155f 652 SUPERFAMILY SSF53300 466 637 2.37E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS11185 669db093832fd05f40334c3929ac155f 652 SMART SM00327 464 646 6.9E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 620 40.422 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 Pfam PF01380 SIS domain 468 598 1.4E-21 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 Pfam PF01380 SIS domain 297 421 3.2E-33 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 Pfam PF13522 Glutamine amidotransferase domain 68 200 1.1E-20 T 28-03-2018 CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 SUPERFAMILY SSF56235 2 243 1.2E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 SUPERFAMILY SSF53697 253 620 3.53E-104 T 28-03-2018 CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 620 3.8E-243 T 28-03-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 Gene3D G3DSA:3.60.20.10 2 247 1.1E-67 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 Gene3D G3DSA:3.40.50.10490 248 465 8.8E-63 T 28-03-2018 CNX65_RS32185 ac0f9c2162c436656bf20da1f21d0e79 620 Gene3D G3DSA:3.40.50.10490 466 618 3.8E-45 T 28-03-2018 CNX65_RS20495 cea3d6174c0fecc5376fb3c78f1528ad 257 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 245 5.1E-88 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CNX65_RS20495 cea3d6174c0fecc5376fb3c78f1528ad 257 Gene3D G3DSA:3.40.30.10 16 203 1.0E-9 T 28-03-2018 CNX65_RS12600 35c813fc2a227c449907dab8423997c8 259 SUPERFAMILY SSF49879 20 89 4.21E-8 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CNX65_RS12600 35c813fc2a227c449907dab8423997c8 259 Gene3D G3DSA:2.60.200.20 34 109 5.7E-4 T 28-03-2018 CNX65_RS07675 bcec16f8247b30d08ab6769d31a0320e 231 Pfam PF13411 MerR HTH family regulatory protein 1 70 1.3E-18 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07675 bcec16f8247b30d08ab6769d31a0320e 231 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 1.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07675 bcec16f8247b30d08ab6769d31a0320e 231 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 1.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07675 bcec16f8247b30d08ab6769d31a0320e 231 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 37 57 1.6E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07675 bcec16f8247b30d08ab6769d31a0320e 231 SMART SM00422 1 71 1.9E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07675 bcec16f8247b30d08ab6769d31a0320e 231 SUPERFAMILY SSF46955 1 75 5.95E-16 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS07675 bcec16f8247b30d08ab6769d31a0320e 231 Gene3D G3DSA:1.10.1660.10 1 148 1.8E-20 T 28-03-2018 CNX65_RS06740 ec46aff7c2b333603ba9d149587ed1fc 237 Pfam PF14428 SCP1.201-like deaminase 117 234 2.4E-24 T 28-03-2018 IPR032724 Deaminase, SCP1.201-like CNX65_RS15140 0fd70cd2cd4f162ff71d49355c687336 257 SUPERFAMILY SSF52540 8 226 5.45E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15140 0fd70cd2cd4f162ff71d49355c687336 257 SMART SM00382 35 221 2.8E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15140 0fd70cd2cd4f162ff71d49355c687336 257 Gene3D G3DSA:3.40.50.300 4 237 3.8E-59 T 28-03-2018 CNX65_RS15140 0fd70cd2cd4f162ff71d49355c687336 257 Pfam PF00005 ABC transporter 27 172 8.9E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS19195 9e85c9f9fcf44d8bdec3c27f90bc0b33 206 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 58 1.0E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19195 9e85c9f9fcf44d8bdec3c27f90bc0b33 206 SUPERFAMILY SSF46689 4 75 3.29E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS19195 9e85c9f9fcf44d8bdec3c27f90bc0b33 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19195 9e85c9f9fcf44d8bdec3c27f90bc0b33 206 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19195 9e85c9f9fcf44d8bdec3c27f90bc0b33 206 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS19195 9e85c9f9fcf44d8bdec3c27f90bc0b33 206 Gene3D G3DSA:1.10.10.60 2 57 7.3E-18 T 28-03-2018 CNX65_RS19195 9e85c9f9fcf44d8bdec3c27f90bc0b33 206 Gene3D G3DSA:1.10.357.10 58 199 3.5E-22 T 28-03-2018 CNX65_RS27445 81f595c498c6f42a0539f01fbc592da8 228 Pfam PF00027 Cyclic nucleotide-binding domain 18 104 4.8E-14 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS27445 81f595c498c6f42a0539f01fbc592da8 228 Gene3D G3DSA:2.60.120.10 1 133 2.8E-17 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS27445 81f595c498c6f42a0539f01fbc592da8 228 Gene3D G3DSA:1.10.10.10 136 214 2.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27445 81f595c498c6f42a0539f01fbc592da8 228 SUPERFAMILY SSF51206 4 131 1.96E-21 T 28-03-2018 IPR018490 Cyclic nucleotide-binding-like CNX65_RS27445 81f595c498c6f42a0539f01fbc592da8 228 SUPERFAMILY SSF46785 139 214 3.91E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27445 81f595c498c6f42a0539f01fbc592da8 228 SMART SM00100 1 118 5.4E-12 T 28-03-2018 IPR000595 Cyclic nucleotide-binding domain CNX65_RS27445 81f595c498c6f42a0539f01fbc592da8 228 Pfam PF13545 Crp-like helix-turn-helix domain 139 212 3.0E-12 T 28-03-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 CNX65_RS27510 ac1987526d15ae1a17384cc43879ec8d 308 Gene3D G3DSA:3.40.630.30 136 301 1.4E-22 T 28-03-2018 CNX65_RS27510 ac1987526d15ae1a17384cc43879ec8d 308 SUPERFAMILY SSF55729 134 297 4.79E-21 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS27510 ac1987526d15ae1a17384cc43879ec8d 308 Pfam PF00583 Acetyltransferase (GNAT) family 193 290 6.2E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS10665 beabef24c8eebd12bc2c8b6fcafdcccf 310 Pfam PF03279 Bacterial lipid A biosynthesis acyltransferase 10 287 2.9E-64 T 28-03-2018 IPR004960 Bacterial lipid A biosynthesis acyltransferase GO:0016021|GO:0016740 CNX65_RS10590 7df713bdb48ce1fd9b631a3e564821a5 286 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 7 186 8.2E-59 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS10590 7df713bdb48ce1fd9b631a3e564821a5 286 SUPERFAMILY SSF51735 4 186 3.71E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS10590 7df713bdb48ce1fd9b631a3e564821a5 286 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 2.7E-29 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS10590 7df713bdb48ce1fd9b631a3e564821a5 286 Gene3D G3DSA:1.10.1040.10 188 286 5.7E-31 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS10590 7df713bdb48ce1fd9b631a3e564821a5 286 PIRSF PIRSF000105 2 286 2.2E-78 T 28-03-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 CNX65_RS10590 7df713bdb48ce1fd9b631a3e564821a5 286 Gene3D G3DSA:3.40.50.720 1 187 1.1E-49 T 28-03-2018 CNX65_RS10590 7df713bdb48ce1fd9b631a3e564821a5 286 SUPERFAMILY SSF48179 189 285 1.79E-28 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS17810 7f6d2e91ac7410148baa7976e30e8d16 317 Gene3D G3DSA:1.10.510.10 69 292 2.8E-13 T 28-03-2018 CNX65_RS17810 7f6d2e91ac7410148baa7976e30e8d16 317 Pfam PF01636 Phosphotransferase enzyme family 70 264 6.5E-11 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS17810 7f6d2e91ac7410148baa7976e30e8d16 317 SUPERFAMILY SSF56112 52 285 5.27E-18 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS33715 799adc8ea0c05485680e44f4134c4143 258 Pfam PF00005 ABC transporter 21 176 6.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS33715 799adc8ea0c05485680e44f4134c4143 258 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS33715 799adc8ea0c05485680e44f4134c4143 258 Gene3D G3DSA:3.40.50.300 1 256 2.9E-61 T 28-03-2018 CNX65_RS33715 799adc8ea0c05485680e44f4134c4143 258 SMART SM00382 29 229 2.0E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS33715 799adc8ea0c05485680e44f4134c4143 258 SUPERFAMILY SSF52540 5 245 5.92E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS33715 799adc8ea0c05485680e44f4134c4143 258 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 258 9.4E-117 T 28-03-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Pfam PF13205 Bacterial Ig-like domain 457 553 1.6E-13 T 28-03-2018 IPR032812 SbsA, Ig-like domain CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Pfam PF13205 Bacterial Ig-like domain 190 285 6.6E-13 T 28-03-2018 IPR032812 SbsA, Ig-like domain CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Pfam PF13205 Bacterial Ig-like domain 722 821 7.5E-10 T 28-03-2018 IPR032812 SbsA, Ig-like domain CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 SUPERFAMILY SSF81296 726 810 7.35E-7 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Pfam PF13313 Domain of unknown function (DUF4082) 562 713 5.5E-54 T 28-03-2018 IPR025141 Domain of unknown function DUF4082 CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Pfam PF13313 Domain of unknown function (DUF4082) 35 177 2.0E-47 T 28-03-2018 IPR025141 Domain of unknown function DUF4082 CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Pfam PF13313 Domain of unknown function (DUF4082) 297 446 1.9E-51 T 28-03-2018 IPR025141 Domain of unknown function DUF4082 CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Gene3D G3DSA:2.60.40.1220 724 822 5.3E-13 T 28-03-2018 CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Gene3D G3DSA:2.60.40.1220 464 553 1.3E-7 T 28-03-2018 CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Gene3D G3DSA:2.60.40.1220 192 273 3.1E-9 T 28-03-2018 CNX65_RS20170 5773aa24fefeb205c64ae5704a537710 824 Gene3D G3DSA:2.60.40.1310 274 400 0.49 T 28-03-2018 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Gene3D G3DSA:1.20.140.10 279 476 3.8E-32 T 28-03-2018 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 162 276 2.9E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Gene3D G3DSA:1.10.540.10 30 161 1.5E-8 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Gene3D G3DSA:2.40.110.10 162 278 7.6E-25 T 28-03-2018 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Gene3D G3DSA:1.20.120.470 477 608 0.001 T 28-03-2018 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Pfam PF12418 Acyl-CoA dehydrogenase N terminal 3 34 6.3E-10 T 28-03-2018 IPR020953 Acyl-CoA dehydrogenase, N-terminal, bacteria CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Pfam PF12806 Acetyl-CoA dehydrogenase C-terminal like 476 608 1.4E-32 T 28-03-2018 IPR025878 Acetyl-CoA dehydrogenase-like C-terminal domain CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 292 455 3.9E-14 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 SUPERFAMILY SSF47203 296 477 5.15E-30 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS34410 708e6ec4030a6c58f41457d7a9e1bbb9 612 SUPERFAMILY SSF56645 56 298 5.89E-44 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS07750 881a0f12bb779562571de70125a6d189 303 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 6 213 3.9E-27 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 PIRSF PIRSF001084 3 666 2.5E-243 T 28-03-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 Pfam PF08532 Beta-galactosidase trimerisation domain 398 590 1.1E-45 T 28-03-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 Gene3D G3DSA:3.40.50.880 395 595 7.0E-51 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 Gene3D G3DSA:3.20.20.80 6 380 8.1E-93 T 28-03-2018 CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 SUPERFAMILY SSF51445 12 369 2.43E-115 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 Pfam PF08533 Beta-galactosidase C-terminal domain 610 665 3.3E-8 T 28-03-2018 IPR013739 Beta-galactosidase C-terminal GO:0004565|GO:0006012 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 Pfam PF02449 Beta-galactosidase 16 387 1.2E-152 T 28-03-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 SUPERFAMILY SSF52317 395 591 5.15E-52 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS03070 301f40abf15fce8eb846f7a3ef20147e 677 Gene3D G3DSA:2.60.40.1180 609 665 9.9E-16 T 28-03-2018 CNX65_RS31255 42b0583d613609cceaa77b19a7a86b6d 117 SMART SM00418 8 86 2.6E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS31255 42b0583d613609cceaa77b19a7a86b6d 117 Gene3D G3DSA:1.10.10.10 1 109 8.2E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31255 42b0583d613609cceaa77b19a7a86b6d 117 SUPERFAMILY SSF46785 4 109 6.71E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31255 42b0583d613609cceaa77b19a7a86b6d 117 Pfam PF12840 Helix-turn-helix domain 9 63 3.4E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31255 42b0583d613609cceaa77b19a7a86b6d 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 6.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS31255 42b0583d613609cceaa77b19a7a86b6d 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 6.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS31255 42b0583d613609cceaa77b19a7a86b6d 117 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 6.1E-9 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS22850 9ff18039007cbe201e319e3767a55a54 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 9 102 5.3E-13 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS22850 9ff18039007cbe201e319e3767a55a54 274 Pfam PF08282 haloacid dehalogenase-like hydrolase 169 252 2.1E-17 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS22850 9ff18039007cbe201e319e3767a55a54 274 Gene3D G3DSA:3.40.50.1000 2 264 5.2E-27 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS22850 9ff18039007cbe201e319e3767a55a54 274 SUPERFAMILY SSF56784 7 257 3.14E-41 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS21455 4a946c8dd4743cd3c18b05cb7f075958 444 Gene3D G3DSA:1.20.1250.20 200 410 1.1E-15 T 28-03-2018 CNX65_RS21455 4a946c8dd4743cd3c18b05cb7f075958 444 Gene3D G3DSA:1.20.1250.20 1 197 2.0E-12 T 28-03-2018 CNX65_RS21455 4a946c8dd4743cd3c18b05cb7f075958 444 Pfam PF07690 Major Facilitator Superfamily 13 227 8.2E-12 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS21455 4a946c8dd4743cd3c18b05cb7f075958 444 SUPERFAMILY SSF103473 7 406 1.57E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 Gene3D G3DSA:2.160.10.10 284 403 7.7E-12 T 28-03-2018 CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 Gene3D G3DSA:3.90.550.10 2 283 2.1E-55 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 13 32 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 4 403 46.91 T 28-03-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 98 106 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 SUPERFAMILY SSF53448 341 358 1.1E-69 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 SUPERFAMILY SSF53448 7 280 1.1E-69 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 Pfam PF00483 Nucleotidyl transferase 9 276 5.3E-69 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 196 206 - T 28-03-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 SUPERFAMILY SSF51161 299 396 2.08E-17 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS03925 ffe27ba1759874d2326cad27e5a860c1 406 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 7 377 1.1E-137 T 28-03-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622 CNX65_RS16730 7bfbfd8dfd85071ef4c1a92e7b6a539c 485 Pfam PF04616 Glycosyl hydrolases family 43 3 274 8.9E-85 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS16730 7bfbfd8dfd85071ef4c1a92e7b6a539c 485 Gene3D G3DSA:2.60.120.200 287 477 1.8E-31 T 28-03-2018 CNX65_RS16730 7bfbfd8dfd85071ef4c1a92e7b6a539c 485 SUPERFAMILY SSF75005 3 283 2.86E-89 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16730 7bfbfd8dfd85071ef4c1a92e7b6a539c 485 Gene3D G3DSA:2.115.10.20 1 281 6.7E-71 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16730 7bfbfd8dfd85071ef4c1a92e7b6a539c 485 SUPERFAMILY SSF49899 290 479 2.57E-22 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS02215 33cc1588fcf70d52c2f992068d1ee002 503 Gene3D G3DSA:3.30.2010.10 69 164 2.2E-10 T 28-03-2018 CNX65_RS02215 33cc1588fcf70d52c2f992068d1ee002 503 Pfam PF01435 Peptidase family M48 84 301 2.6E-12 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CNX65_RS21095 dea35785a76d7cab578f65f30561af39 165 Gene3D G3DSA:3.40.630.30 3 164 2.1E-28 T 28-03-2018 CNX65_RS21095 dea35785a76d7cab578f65f30561af39 165 SUPERFAMILY SSF55729 5 144 1.1E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS21095 dea35785a76d7cab578f65f30561af39 165 Pfam PF00583 Acetyltransferase (GNAT) family 36 140 1.4E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS24340 a119a51bf4dfa7f3e0e8eaae7d334b26 530 Pfam PF00999 Sodium/hydrogen exchanger family 8 403 8.8E-58 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CNX65_RS24340 a119a51bf4dfa7f3e0e8eaae7d334b26 530 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 8 521 9.9E-122 T 28-03-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 Gene3D G3DSA:1.20.1250.20 5 194 3.8E-31 T 28-03-2018 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 Pfam PF07690 Major Facilitator Superfamily 17 354 3.3E-47 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 TIGRFAM TIGR00710 efflux_Bcr_CflA: drug resistance transporter, Bcr/CflA subfamily 9 388 2.8E-94 T 28-03-2018 IPR004812 Drug resistance transporter Bcr/CmlA subfamily GO:0005215|GO:0006810|GO:0016021 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 ProSitePatterns PS00216 Sugar transport proteins signature 1. 63 79 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 SUPERFAMILY SSF103473 7 401 1.44E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 PRINTS PR01036 Tetracycline resistance protein TetB signature 133 157 1.2E-5 T 28-03-2018 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 PRINTS PR01036 Tetracycline resistance protein TetB signature 103 123 1.2E-5 T 28-03-2018 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 PRINTS PR01036 Tetracycline resistance protein TetB signature 282 306 1.2E-5 T 28-03-2018 CNX65_RS28155 010177c4e6d5f8ec27f9227ee82df00a 414 Gene3D G3DSA:1.20.1250.20 206 406 1.2E-15 T 28-03-2018 CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 SUPERFAMILY SSF51556 60 354 1.41E-92 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 Gene3D G3DSA:3.20.20.140 75 354 1.6E-105 T 28-03-2018 CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 TIGRFAM TIGR00221 nagA: N-acetylglucosamine-6-phosphate deacetylase 11 374 6.1E-80 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 PIRSF PIRSF038994 9 385 3.2E-113 T 28-03-2018 IPR003764 N-acetylglucosamine-6-phosphate deacetylase GO:0006044|GO:0008448 KEGG: 00052+3.5.1.25|KEGG: 00520+3.5.1.25|MetaCyc: PWY-6906|MetaCyc: PWY-7077|MetaCyc: PWY-7395|Reactome: R-HSA-446210 CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 Gene3D G3DSA:2.30.40.10 7 74 1.8E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 SUPERFAMILY SSF51338 5 60 3.33E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 SUPERFAMILY SSF51338 354 372 3.33E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS34210 f0053372e3a38a5cbc9e9c0357d470e5 385 Pfam PF01979 Amidohydrolase family 57 374 2.1E-25 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS10755 d88e9569de006c61cc0bdd054f2143e3 175 Pfam PF14081 Domain of unknown function (DUF4262) 27 148 3.6E-33 T 28-03-2018 IPR025358 Protein of unknown function DUF4262 CNX65_RS14320 e5851bcf01cceba10a5342ac773ce701 946 Gene3D G3DSA:2.60.120.260 797 946 3.7E-27 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS14320 e5851bcf01cceba10a5342ac773ce701 946 Gene3D G3DSA:1.50.10.10 345 676 1.2E-13 T 28-03-2018 CNX65_RS14320 e5851bcf01cceba10a5342ac773ce701 946 SUPERFAMILY SSF49785 802 944 6.81E-10 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS14320 e5851bcf01cceba10a5342ac773ce701 946 SUPERFAMILY SSF48208 267 743 9.64E-22 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS14320 e5851bcf01cceba10a5342ac773ce701 946 Pfam PF00754 F5/8 type C domain 817 938 2.3E-9 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CNX65_RS08880 f5d933de5d4c4ce866699a436493961e 208 SUPERFAMILY SSF63965 3 205 1.44E-72 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CNX65_RS08880 f5d933de5d4c4ce866699a436493961e 208 Pfam PF02570 Precorrin-8X methylmutase 10 205 5.8E-72 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CNX65_RS08880 f5d933de5d4c4ce866699a436493961e 208 Gene3D G3DSA:3.40.50.10230 2 208 4.0E-78 T 28-03-2018 IPR003722 Cobalamin (vitamin B12) biosynthesis CobH/CbiC, precorrin-8X methylmutase GO:0009236|GO:0016993 CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 389 543 2.0E-27 T 28-03-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 426 445 - T 28-03-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 SUPERFAMILY SSF52518 4 178 3.93E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 SUPERFAMILY SSF52467 156 357 1.93E-36 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 Gene3D G3DSA:3.40.50.970 342 551 2.7E-39 T 28-03-2018 CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 SUPERFAMILY SSF52518 366 560 7.51E-48 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 4 172 2.7E-45 T 28-03-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 Gene3D G3DSA:3.40.50.1220 189 341 1.8E-33 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 200 329 3.9E-24 T 28-03-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 CNX65_RS17105 a92a20bbd6218a8134d941d050457d7f 586 Gene3D G3DSA:3.40.50.970 1 188 1.3E-43 T 28-03-2018 CNX65_RS09985 f794d38ab4888356aaa68c86cc340088 382 Gene3D G3DSA:3.40.50.1970 21 191 3.2E-43 T 28-03-2018 CNX65_RS09985 f794d38ab4888356aaa68c86cc340088 382 Gene3D G3DSA:1.20.1090.10 192 382 3.4E-54 T 28-03-2018 CNX65_RS09985 f794d38ab4888356aaa68c86cc340088 382 SUPERFAMILY SSF56796 30 378 1.14E-93 T 28-03-2018 CNX65_RS09985 f794d38ab4888356aaa68c86cc340088 382 Pfam PF01761 3-dehydroquinate synthase 87 334 4.7E-86 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS09985 f794d38ab4888356aaa68c86cc340088 382 PIRSF PIRSF001455 24 381 1.4E-92 T 28-03-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS09985 f794d38ab4888356aaa68c86cc340088 382 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 20 380 34.487 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS09985 f794d38ab4888356aaa68c86cc340088 382 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 33 376 1.3E-95 T 28-03-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS04640 ab10884a68905be871912fe58d89314f 166 Pfam PF03551 Transcriptional regulator PadR-like family 11 81 3.9E-7 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS04640 ab10884a68905be871912fe58d89314f 166 SUPERFAMILY SSF46785 8 162 4.66E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04640 ab10884a68905be871912fe58d89314f 166 Gene3D G3DSA:1.10.10.10 6 88 2.3E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00140 52f8d464a4dd05b3c5bce79dc0b80d8f 417 Pfam PF12401 Protein of unknown function (DUF2662) 4 121 7.4E-39 T 28-03-2018 IPR022128 Domain of unknown function DUF3662 CNX65_RS00140 52f8d464a4dd05b3c5bce79dc0b80d8f 417 Pfam PF00498 FHA domain 345 407 9.1E-17 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CNX65_RS00140 52f8d464a4dd05b3c5bce79dc0b80d8f 417 SUPERFAMILY SSF49879 321 414 2.68E-29 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CNX65_RS00140 52f8d464a4dd05b3c5bce79dc0b80d8f 417 SMART SM00240 343 393 1.2E-12 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CNX65_RS00140 52f8d464a4dd05b3c5bce79dc0b80d8f 417 Gene3D G3DSA:2.60.200.20 280 417 8.2E-26 T 28-03-2018 CNX65_RS17710 b5db6f9d789bd9cb6476b50b5b625ff4 149 ProSitePatterns PS00893 Nudix box signature. 35 56 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS17710 b5db6f9d789bd9cb6476b50b5b625ff4 149 Gene3D G3DSA:3.90.79.10 2 133 8.0E-21 T 28-03-2018 CNX65_RS17710 b5db6f9d789bd9cb6476b50b5b625ff4 149 Pfam PF00293 NUDIX domain 4 120 1.1E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS17710 b5db6f9d789bd9cb6476b50b5b625ff4 149 SUPERFAMILY SSF55811 4 123 2.44E-21 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS28995 9a0f8dbdc359d9dafb3638a29bb047fa 263 PIRSF PIRSF005650 20 262 4.7E-87 T 28-03-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 CNX65_RS28995 9a0f8dbdc359d9dafb3638a29bb047fa 263 SUPERFAMILY SSF53633 24 254 9.43E-71 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS28995 9a0f8dbdc359d9dafb3638a29bb047fa 263 Gene3D G3DSA:3.40.1160.10 6 256 8.0E-46 T 28-03-2018 CNX65_RS28995 9a0f8dbdc359d9dafb3638a29bb047fa 263 Pfam PF00696 Amino acid kinase family 26 234 1.2E-31 T 28-03-2018 IPR001048 Aspartate/glutamate/uridylate kinase CNX65_RS28995 9a0f8dbdc359d9dafb3638a29bb047fa 263 Hamap MF_01220_B Uridylate kinase [pyrH]. 22 255 42.476 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CNX65_RS28995 9a0f8dbdc359d9dafb3638a29bb047fa 263 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 24 255 1.2E-87 T 28-03-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 CNX65_RS23560 4a122f6fe5a864b6585e8f877bf28155 282 Pfam PF14062 Domain of unknown function (DUF4253) 172 282 8.0E-33 T 28-03-2018 IPR025349 Domain of unknown function DUF4253 CNX65_RS05665 d95f39fc96880be7100804ab92e671da 165 Gene3D G3DSA:3.40.1800.10 62 132 1.7E-17 T 28-03-2018 CNX65_RS05665 d95f39fc96880be7100804ab92e671da 165 Pfam PF14279 HNH endonuclease 81 127 3.1E-13 T 28-03-2018 IPR029471 HNH endonuclease 5 CNX65_RS05665 d95f39fc96880be7100804ab92e671da 165 SMART SM00507 68 117 8.2E-15 T 28-03-2018 IPR003615 HNH nuclease CNX65_RS15845 78506f57c53b0dc1037c7b6e2a2ba8c5 347 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 259 344 5.0E-9 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS15845 78506f57c53b0dc1037c7b6e2a2ba8c5 347 Gene3D G3DSA:3.40.47.10 187 347 2.7E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15845 78506f57c53b0dc1037c7b6e2a2ba8c5 347 SUPERFAMILY SSF53901 1 198 3.46E-25 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15845 78506f57c53b0dc1037c7b6e2a2ba8c5 347 Gene3D G3DSA:3.40.47.10 1 186 2.0E-18 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15845 78506f57c53b0dc1037c7b6e2a2ba8c5 347 SUPERFAMILY SSF53901 239 345 4.9E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15845 78506f57c53b0dc1037c7b6e2a2ba8c5 347 SUPERFAMILY SSF53901 181 211 4.9E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21930 a1d0b4bd761f8e8b6d50e72fa9695b5b 271 SUPERFAMILY SSF51735 81 267 4.4E-17 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21930 a1d0b4bd761f8e8b6d50e72fa9695b5b 271 Pfam PF13460 NAD(P)H-binding 80 254 3.9E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21930 a1d0b4bd761f8e8b6d50e72fa9695b5b 271 Gene3D G3DSA:3.40.50.720 34 219 4.9E-8 T 28-03-2018 CNX65_RS04020 125aefa1e5d0059cc612558bf24f9717 201 Pfam PF03551 Transcriptional regulator PadR-like family 22 97 7.4E-12 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS04020 125aefa1e5d0059cc612558bf24f9717 201 Gene3D G3DSA:1.10.10.10 9 108 1.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04020 125aefa1e5d0059cc612558bf24f9717 201 SUPERFAMILY SSF46785 18 189 2.54E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21395 9819c61f437dbb96dc5d11511ef445c6 244 Pfam PF12697 Alpha/beta hydrolase family 20 239 1.9E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS21395 9819c61f437dbb96dc5d11511ef445c6 244 SUPERFAMILY SSF53474 15 242 8.98E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21395 9819c61f437dbb96dc5d11511ef445c6 244 Gene3D G3DSA:3.40.50.1820 2 243 8.6E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21395 9819c61f437dbb96dc5d11511ef445c6 244 PRINTS PR00111 Alpha/beta hydrolase fold signature 88 101 2.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS21395 9819c61f437dbb96dc5d11511ef445c6 244 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 2.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS21395 9819c61f437dbb96dc5d11511ef445c6 244 PRINTS PR00111 Alpha/beta hydrolase fold signature 191 205 2.5E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS07540 4ab603aa2d7d855be23cd20a0de67c17 674 Pfam PF13520 Amino acid permease 52 459 2.9E-26 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS16230 b27e641f3a0b25dd1f45d2062e6c0e3b 378 Pfam PF01757 Acyltransferase family 12 340 5.1E-25 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS12490 15763b849e89edd96b030aa64b1c4b39 229 Gene3D G3DSA:1.10.10.10 123 229 6.9E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12490 15763b849e89edd96b030aa64b1c4b39 229 Gene3D G3DSA:3.40.50.2300 1 122 1.7E-36 T 28-03-2018 CNX65_RS12490 15763b849e89edd96b030aa64b1c4b39 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 2.2E-17 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS12490 15763b849e89edd96b030aa64b1c4b39 229 SUPERFAMILY SSF52172 2 175 7.97E-41 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS12490 15763b849e89edd96b030aa64b1c4b39 229 Pfam PF00072 Response regulator receiver domain 4 113 3.3E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12490 15763b849e89edd96b030aa64b1c4b39 229 SMART SM00448 2 112 1.4E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12490 15763b849e89edd96b030aa64b1c4b39 229 SMART SM00862 149 224 2.1E-13 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS05120 bcc8df0857aa3ceba26e3a170d17eee3 198 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 2 189 1.7E-48 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CNX65_RS05120 bcc8df0857aa3ceba26e3a170d17eee3 198 SUPERFAMILY SSF52972 2 193 3.92E-65 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CNX65_RS05120 bcc8df0857aa3ceba26e3a170d17eee3 198 Hamap MF_01405 dITP/XTP pyrophosphatase [rdgB]. 1 194 48.139 T 28-03-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 CNX65_RS05120 bcc8df0857aa3ceba26e3a170d17eee3 198 Gene3D G3DSA:3.90.950.10 1 197 1.2E-76 T 28-03-2018 IPR029001 Inosine triphosphate pyrophosphatase-like CNX65_RS05120 bcc8df0857aa3ceba26e3a170d17eee3 198 Pfam PF01725 Ham1 family 3 189 2.0E-54 T 28-03-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 Reactome: R-HSA-74259 CNX65_RS32940 faa05a2e3f9902ac0c398b07475f0b81 230 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 13 227 2.4E-64 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CNX65_RS32940 faa05a2e3f9902ac0c398b07475f0b81 230 SUPERFAMILY SSF53335 6 223 1.35E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS32940 faa05a2e3f9902ac0c398b07475f0b81 230 Pfam PF01209 ubiE/COQ5 methyltransferase family 10 227 2.4E-54 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CNX65_RS32940 faa05a2e3f9902ac0c398b07475f0b81 230 ProSitePatterns PS01184 ubiE/COQ5 methyltransferase family signature 2. 135 149 - T 28-03-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 CNX65_RS32940 faa05a2e3f9902ac0c398b07475f0b81 230 Gene3D G3DSA:3.40.50.150 3 228 4.9E-34 T 28-03-2018 CNX65_RS32940 faa05a2e3f9902ac0c398b07475f0b81 230 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 4 227 31.811 T 28-03-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|KEGG: 00564+2.1.1.16|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 CNX65_RS24555 f1a1e6610fa6a312d5ccea3de22169cf 206 Pfam PF01300 Telomere recombination 23 198 1.1E-42 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CNX65_RS24555 f1a1e6610fa6a312d5ccea3de22169cf 206 SUPERFAMILY SSF55821 1 204 1.01E-60 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CNX65_RS24555 f1a1e6610fa6a312d5ccea3de22169cf 206 Gene3D G3DSA:3.90.870.10 1 205 1.6E-56 T 28-03-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain CNX65_RS24555 f1a1e6610fa6a312d5ccea3de22169cf 206 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 7 200 2.5E-57 T 28-03-2018 IPR006070 YrdC-like domain GO:0003725 CNX65_RS28180 f19f13416a2a35a5935e4d346dd2268f 218 Gene3D G3DSA:1.10.10.60 1 56 1.4E-14 T 28-03-2018 CNX65_RS28180 f19f13416a2a35a5935e4d346dd2268f 218 Gene3D G3DSA:1.10.357.10 70 218 4.3E-34 T 28-03-2018 CNX65_RS28180 f19f13416a2a35a5935e4d346dd2268f 218 SUPERFAMILY SSF48498 74 217 8.12E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS28180 f19f13416a2a35a5935e4d346dd2268f 218 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 72 213 4.9E-12 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CNX65_RS28180 f19f13416a2a35a5935e4d346dd2268f 218 SUPERFAMILY SSF46689 2 52 1.2E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS28180 f19f13416a2a35a5935e4d346dd2268f 218 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 46 3.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 SUPERFAMILY SSF51735 153 328 1.4E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 SMART SM00829 13 362 7.6E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 SUPERFAMILY SSF50129 4 186 8.37E-51 T 28-03-2018 IPR011032 GroES-like CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 Pfam PF00107 Zinc-binding dehydrogenase 190 323 7.8E-26 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 TIGRFAM TIGR03451 mycoS_dep_FDH: S-(hydroxymethyl)mycothiol dehydrogenase 4 362 4.1E-167 T 28-03-2018 IPR017816 S-(hydroxymethyl)mycothiol dehydrogenase KEGG: 00072+1.1.1.30|KEGG: 00650+1.1.1.30 CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 SUPERFAMILY SSF50129 311 361 3.2E-5 T 28-03-2018 IPR011032 GroES-like CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 Gene3D G3DSA:3.40.50.10730 175 305 7.2E-31 T 28-03-2018 CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 62 76 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 29 146 1.2E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS23180 4705de59f72fb9497907cfe1489d4c7f 366 Gene3D G3DSA:3.90.180.10 6 174 5.7E-43 T 28-03-2018 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 SUPERFAMILY SSF51246 333 448 2.93E-37 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 SUPERFAMILY SSF52440 2 116 7.91E-45 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Gene3D G3DSA:3.30.1490.20 133 205 7.5E-22 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 118 326 5.7E-78 T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 SMART SM00878 338 442 1.3E-55 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 156 170 - T 28-03-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 SUPERFAMILY SSF51230 566 638 7.46E-19 T 28-03-2018 IPR011053 Single hybrid motif CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 596 613 - T 28-03-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Pfam PF02785 Biotin carboxylase C-terminal domain 338 442 2.9E-34 T 28-03-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 SUPERFAMILY SSF56059 86 342 1.4E-67 T 28-03-2018 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Gene3D G3DSA:3.40.50.20 4 132 1.1E-48 T 28-03-2018 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Gene3D G3DSA:3.30.470.20 207 445 5.1E-102 T 28-03-2018 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Pfam PF00364 Biotin-requiring enzyme 574 637 1.0E-13 T 28-03-2018 IPR000089 Biotin/lipoyl attachment CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Gene3D G3DSA:2.40.50.100 572 640 4.1E-15 T 28-03-2018 CNX65_RS30660 1d5e7f8e74b489437e64eac03272d350 644 Pfam PF00289 Biotin carboxylase, N-terminal domain 5 113 3.8E-41 T 28-03-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 CNX65_RS28310 1d6da722b03e891479a0f94e203e9ac4 814 Gene3D G3DSA:3.90.260.10 413 554 1.1E-16 T 28-03-2018 IPR002931 Transglutaminase-like CNX65_RS28310 1d6da722b03e891479a0f94e203e9ac4 814 SMART SM00460 476 545 1.9E-19 T 28-03-2018 IPR002931 Transglutaminase-like CNX65_RS28310 1d6da722b03e891479a0f94e203e9ac4 814 SUPERFAMILY SSF54001 423 546 2.8E-30 T 28-03-2018 CNX65_RS28310 1d6da722b03e891479a0f94e203e9ac4 814 Pfam PF01841 Transglutaminase-like superfamily 428 543 2.1E-25 T 28-03-2018 IPR002931 Transglutaminase-like CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 Gene3D G3DSA:2.60.120.200 698 921 5.6E-38 T 28-03-2018 CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 Gene3D G3DSA:2.60.120.200 922 1145 2.3E-31 T 28-03-2018 CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 SMART SM00560 773 911 2.2E-11 T 28-03-2018 IPR006558 LamG-like jellyroll fold CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 SMART SM00560 990 1135 2.0E-5 T 28-03-2018 IPR006558 LamG-like jellyroll fold CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 974 1137 2.0E-23 T 28-03-2018 CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 757 914 6.9E-25 T 28-03-2018 CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 SUPERFAMILY SSF49899 924 1143 2.96E-26 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 Gene3D G3DSA:2.60.40.1310 570 697 6.8E-7 T 28-03-2018 CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 ProDom PD039135 WALL-ASSOCIATED REPEAT PROTEIN CELL WALL HYDROLASE PRECURSOR SIGNAL TRANSMEMBRANE RETICULOCYTE 63 250 1.0E-5 T 28-03-2018 CNX65_RS24075 62431e6bdc0f8bffa8acef7777fe59b4 1147 SUPERFAMILY SSF49899 707 920 1.92E-30 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 PRINTS PR00364 Disease resistance protein signature 139 153 2.5E-7 T 28-03-2018 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 PRINTS PR00364 Disease resistance protein signature 63 78 2.5E-7 T 28-03-2018 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 PRINTS PR00364 Disease resistance protein signature 225 239 2.5E-7 T 28-03-2018 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 SMART SM00028 474 507 0.25 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 SMART SM00028 634 667 430.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 SMART SM00028 594 627 40.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 Pfam PF13374 Tetratricopeptide repeat 476 505 0.019 T 28-03-2018 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 SUPERFAMILY SSF52540 48 286 2.37E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 Gene3D G3DSA:1.25.40.10 415 689 1.9E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 Gene3D G3DSA:3.40.50.300 37 178 4.6E-15 T 28-03-2018 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 SMART SM00382 60 193 3.3E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 SUPERFAMILY SSF48452 476 666 4.81E-19 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20935 43badeb648e46db9f6a7459ee3e93912 692 Pfam PF13424 Tetratricopeptide repeat 517 581 2.1E-7 T 28-03-2018 CNX65_RS29825 b9528f6439ff1df369a4557730845e4f 142 Pfam PF00102 Protein-tyrosine phosphatase 45 110 5.6E-5 T 28-03-2018 IPR000242 PTP type protein phosphatase GO:0004725|GO:0006470 CNX65_RS29825 b9528f6439ff1df369a4557730845e4f 142 Gene3D G3DSA:3.90.190.10 34 138 2.1E-12 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CNX65_RS29825 b9528f6439ff1df369a4557730845e4f 142 SUPERFAMILY SSF52799 47 136 1.5E-17 T 28-03-2018 IPR029021 Protein-tyrosine phosphatase-like CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 SUPERFAMILY SSF55874 242 382 1.7E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 Gene3D G3DSA:3.30.450.40 8 163 3.3E-4 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 Gene3D G3DSA:3.30.565.10 164 383 2.5E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 SMART SM00387 275 385 2.2E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 SUPERFAMILY SSF55781 64 180 5.15E-6 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 Pfam PF06580 Histidine kinase 186 264 7.1E-23 T 28-03-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 Pfam PF13492 GAF domain 96 172 7.5E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS26280 36cc9aaf3d6ef5c1968a6c89d4888b64 391 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 284 383 3.6E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS17375 d160282af58c05e0543597fa9f2f7aba 352 Gene3D G3DSA:1.25.40.10 76 297 3.6E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS14270 77ef04508d9836dfc3d26a4d4fb6cc61 305 SUPERFAMILY SSF51735 6 270 2.17E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14270 77ef04508d9836dfc3d26a4d4fb6cc61 305 Gene3D G3DSA:3.40.50.720 1 258 4.9E-30 T 28-03-2018 CNX65_RS14270 77ef04508d9836dfc3d26a4d4fb6cc61 305 Pfam PF05368 NmrA-like family 7 244 1.5E-41 T 28-03-2018 IPR008030 NmrA-like domain Reactome: R-HSA-70635 CNX65_RS02695 a25d338164f82e05dd64c7159fd44af8 419 Pfam PF13796 Putative sensor 54 207 5.3E-11 T 28-03-2018 IPR025828 Putative sensor domain CNX65_RS02695 a25d338164f82e05dd64c7159fd44af8 419 Gene3D G3DSA:3.30.565.10 294 419 1.7E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02695 a25d338164f82e05dd64c7159fd44af8 419 SUPERFAMILY SSF55874 324 417 4.06E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02695 a25d338164f82e05dd64c7159fd44af8 419 SMART SM00387 329 419 1.6E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02695 a25d338164f82e05dd64c7159fd44af8 419 Pfam PF07730 Histidine kinase 234 296 4.3E-10 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS23225 e5bc386d1071c42a363dd540ef310767 693 Gene3D G3DSA:3.50.50.60 18 263 8.8E-11 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23225 e5bc386d1071c42a363dd540ef310767 693 SUPERFAMILY SSF51905 24 96 5.57E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23225 e5bc386d1071c42a363dd540ef310767 693 SUPERFAMILY SSF51905 135 266 5.57E-8 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23225 e5bc386d1071c42a363dd540ef310767 693 Pfam PF13454 FAD-NAD(P)-binding 26 206 9.2E-44 T 28-03-2018 CNX65_RS06320 e497342cf330cb33ecc089e8d51c88bc 351 SUPERFAMILY SSF56574 6 351 9.56E-74 T 28-03-2018 IPR023796 Serpin domain CNX65_RS06320 e497342cf330cb33ecc089e8d51c88bc 351 Pfam PF00079 Serpin (serine protease inhibitor) 8 351 3.3E-65 T 28-03-2018 IPR023796 Serpin domain CNX65_RS06320 e497342cf330cb33ecc089e8d51c88bc 351 Gene3D G3DSA:3.30.497.10 4 162 5.6E-34 T 28-03-2018 CNX65_RS06320 e497342cf330cb33ecc089e8d51c88bc 351 SMART SM00093 11 351 7.6E-54 T 28-03-2018 IPR023796 Serpin domain CNX65_RS06320 e497342cf330cb33ecc089e8d51c88bc 351 Gene3D G3DSA:2.30.39.10 163 351 3.1E-42 T 28-03-2018 CNX65_RS15390 958ed16d30582cdbe85191a679969b8a 548 SUPERFAMILY SSF52540 396 527 1.42E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15390 958ed16d30582cdbe85191a679969b8a 548 Pfam PF13671 AAA domain 399 524 1.0E-15 T 28-03-2018 CNX65_RS15390 958ed16d30582cdbe85191a679969b8a 548 Pfam PF09414 RNA ligase 33 182 4.5E-24 T 28-03-2018 IPR021122 RNA ligase domain, REL/Rln2 CNX65_RS15390 958ed16d30582cdbe85191a679969b8a 548 Gene3D G3DSA:3.40.50.300 397 529 3.2E-11 T 28-03-2018 CNX65_RS15390 958ed16d30582cdbe85191a679969b8a 548 SUPERFAMILY SSF56091 3 205 6.47E-35 T 28-03-2018 CNX65_RS00170 aef17852b8fe833bead7932b507d8105 221 SUPERFAMILY SSF46689 24 94 6.48E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS00170 aef17852b8fe833bead7932b507d8105 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 80 3.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS00170 aef17852b8fe833bead7932b507d8105 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 55 78 9.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS00170 aef17852b8fe833bead7932b507d8105 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 47 9.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS00170 aef17852b8fe833bead7932b507d8105 221 Gene3D G3DSA:1.10.357.10 17 221 1.6E-28 T 28-03-2018 CNX65_RS00170 aef17852b8fe833bead7932b507d8105 221 ProSitePatterns PS01081 TetR-type HTH domain signature. 46 77 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS13745 576a3d45e15af85399be4f26161f22ea 605 Gene3D G3DSA:3.40.50.1460 372 602 5.0E-14 T 28-03-2018 CNX65_RS13745 576a3d45e15af85399be4f26161f22ea 605 Pfam PF12770 CHAT domain 398 584 2.0E-10 T 28-03-2018 IPR024983 CHAT domain CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 265 290 3.5E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 116 143 3.5E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 94 116 3.5E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 42 54 3.5E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 243 265 3.5E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 10 36 3.5E-56 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 SUPERFAMILY SSF53328 94 291 1.06E-56 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 11 291 1.2E-98 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 PIRSF PIRSF036480 5 291 4.4E-108 T 28-03-2018 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 Gene3D G3DSA:3.30.70.260 2 89 3.7E-25 T 28-03-2018 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 Pfam PF00551 Formyl transferase 94 271 1.5E-38 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 Gene3D G3DSA:3.40.50.170 90 288 5.3E-52 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 5 291 46.961 T 28-03-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497 CNX65_RS33345 6a90b8fc80735f597e8a3b23e889bfbe 291 SUPERFAMILY SSF55021 7 88 1.71E-14 T 28-03-2018 CNX65_RS34715 1228d3aaa1e8ee7897ab49a6507cdf46 707 Gene3D G3DSA:2.120.10.30 441 696 5.6E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS34715 1228d3aaa1e8ee7897ab49a6507cdf46 707 Gene3D G3DSA:3.40.50.720 62 440 1.3E-4 T 28-03-2018 CNX65_RS34715 1228d3aaa1e8ee7897ab49a6507cdf46 707 Pfam PF05787 Bacterial protein of unknown function (DUF839) 119 668 9.0E-165 T 28-03-2018 IPR008557 Protein of unknown function DUF839 CNX65_RS34715 1228d3aaa1e8ee7897ab49a6507cdf46 707 SUPERFAMILY SSF63829 505 525 5.56E-8 T 28-03-2018 CNX65_RS34715 1228d3aaa1e8ee7897ab49a6507cdf46 707 SUPERFAMILY SSF63829 594 670 5.56E-8 T 28-03-2018 CNX65_RS34715 1228d3aaa1e8ee7897ab49a6507cdf46 707 SUPERFAMILY SSF63829 320 454 5.56E-8 T 28-03-2018 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 SUPERFAMILY SSF118215 15 412 1.15E-95 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 PRINTS PR00173 Glutamate-aspartate symporter signature 11 31 1.1E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 PRINTS PR00173 Glutamate-aspartate symporter signature 363 383 1.1E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 PRINTS PR00173 Glutamate-aspartate symporter signature 200 219 1.1E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 PRINTS PR00173 Glutamate-aspartate symporter signature 53 73 1.1E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 PRINTS PR00173 Glutamate-aspartate symporter signature 86 111 1.1E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 PRINTS PR00173 Glutamate-aspartate symporter signature 227 246 1.1E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 PRINTS PR00173 Glutamate-aspartate symporter signature 301 327 1.1E-28 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 Pfam PF00375 Sodium:dicarboxylate symporter family 15 412 1.2E-102 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS31400 013de85847e34f4de51bf6629894c4b8 446 Gene3D G3DSA:1.10.3860.10 3 420 1.4E-103 T 28-03-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 Hamap MF_00242 Arginine deiminase [arcA]. 1 394 40.047 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 SUPERFAMILY SSF55909 1 394 4.71E-113 T 28-03-2018 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 Pfam PF02274 Amidinotransferase 13 390 4.0E-97 T 28-03-2018 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 PRINTS PR01466 Bacterial arginine deiminase signature 350 364 4.5E-38 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 PRINTS PR01466 Bacterial arginine deiminase signature 145 163 4.5E-38 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 PRINTS PR01466 Bacterial arginine deiminase signature 330 347 4.5E-38 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 PRINTS PR01466 Bacterial arginine deiminase signature 373 391 4.5E-38 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 PRINTS PR01466 Bacterial arginine deiminase signature 173 188 4.5E-38 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 Gene3D G3DSA:3.75.10.10 1 392 2.7E-95 T 28-03-2018 CNX65_RS00420 9e8920ab06ec9d0798259a67337361f7 395 PIRSF PIRSF006356 1 394 2.9E-130 T 28-03-2018 IPR003876 Arginine deiminase GO:0006527|GO:0016990 KEGG: 00220+3.5.3.6|MetaCyc: PWY-4981 CNX65_RS14580 67d2290bdbb5e35bc68ee32f93539ad5 482 Gene3D G3DSA:1.20.1250.20 17 204 1.9E-30 T 28-03-2018 CNX65_RS14580 67d2290bdbb5e35bc68ee32f93539ad5 482 Pfam PF07690 Major Facilitator Superfamily 25 419 4.1E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS14580 67d2290bdbb5e35bc68ee32f93539ad5 482 Gene3D G3DSA:1.20.1250.20 265 478 4.4E-22 T 28-03-2018 CNX65_RS14580 67d2290bdbb5e35bc68ee32f93539ad5 482 SUPERFAMILY SSF103473 9 206 3.14E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS14580 67d2290bdbb5e35bc68ee32f93539ad5 482 SUPERFAMILY SSF103473 254 463 3.14E-57 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15290 ff6dd4a74929a8843bcffeedb052525b 355 Gene3D G3DSA:3.90.350.10 71 330 6.8E-5 T 28-03-2018 IPR014736 Transposase, Tn5-like, core CNX65_RS15290 ff6dd4a74929a8843bcffeedb052525b 355 Pfam PF13546 DDE superfamily endonuclease 19 225 2.6E-33 T 28-03-2018 CNX65_RS33950 b293c1c12e87a4839c81f46ba73771bd 204 Pfam PF12079 Protein of unknown function (DUF3558) 17 169 4.3E-14 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS00520 18c85b189ba3c2d30c3176b104d21fe1 280 SUPERFAMILY SSF52540 3 220 9.12E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00520 18c85b189ba3c2d30c3176b104d21fe1 280 Pfam PF00005 ABC transporter 20 156 2.7E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS00520 18c85b189ba3c2d30c3176b104d21fe1 280 Gene3D G3DSA:3.40.50.300 4 230 4.9E-51 T 28-03-2018 CNX65_RS00520 18c85b189ba3c2d30c3176b104d21fe1 280 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS00520 18c85b189ba3c2d30c3176b104d21fe1 280 SMART SM00382 29 205 5.4E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS25925 8eb3301f03ac4e4db05779c6e6dfc3bb 165 Gene3D G3DSA:3.40.50.450 1 164 5.4E-36 T 28-03-2018 CNX65_RS25925 8eb3301f03ac4e4db05779c6e6dfc3bb 165 SUPERFAMILY SSF102405 2 160 1.28E-14 T 28-03-2018 CNX65_RS29710 7dcf826a9f035d20a270a04bae73eb01 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 7 64 6.0E-16 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS29710 7dcf826a9f035d20a270a04bae73eb01 295 Gene3D G3DSA:3.40.190.10 91 180 3.9E-21 T 28-03-2018 CNX65_RS29710 7dcf826a9f035d20a270a04bae73eb01 295 SUPERFAMILY SSF53850 95 291 1.0E-36 T 28-03-2018 CNX65_RS29710 7dcf826a9f035d20a270a04bae73eb01 295 Gene3D G3DSA:3.40.190.10 181 264 2.3E-20 T 28-03-2018 CNX65_RS29710 7dcf826a9f035d20a270a04bae73eb01 295 Gene3D G3DSA:1.10.10.10 2 89 4.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29710 7dcf826a9f035d20a270a04bae73eb01 295 Pfam PF03466 LysR substrate binding domain 91 290 1.8E-40 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS29710 7dcf826a9f035d20a270a04bae73eb01 295 SUPERFAMILY SSF46785 5 113 2.89E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13530 3519d197dbcc1134aa0983e59f015581 671 Pfam PF00891 O-methyltransferase 444 654 1.0E-37 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CNX65_RS13530 3519d197dbcc1134aa0983e59f015581 671 Pfam PF16864 Dimerisation domain 354 427 1.5E-8 T 28-03-2018 IPR031725 Acetylserotonin O-methyltransferase, dimerisation domain CNX65_RS13530 3519d197dbcc1134aa0983e59f015581 671 SUPERFAMILY SSF46785 352 432 8.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13530 3519d197dbcc1134aa0983e59f015581 671 Gene3D G3DSA:3.40.50.150 431 670 7.4E-36 T 28-03-2018 CNX65_RS13530 3519d197dbcc1134aa0983e59f015581 671 Gene3D G3DSA:1.10.10.10 350 430 2.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13530 3519d197dbcc1134aa0983e59f015581 671 SUPERFAMILY SSF53335 442 665 2.61E-45 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 Pfam PF00196 Bacterial regulatory proteins, luxR family 118 171 7.9E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 SMART SM00421 116 173 1.1E-16 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 SUPERFAMILY SSF46894 111 172 2.55E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 Pfam PF03795 YCII-related domain 17 88 1.5E-10 T 28-03-2018 IPR005545 YCII-related CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 149 161 9.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 133 149 9.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 119 133 9.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 Gene3D G3DSA:1.10.10.10 108 175 9.7E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 SUPERFAMILY SSF54909 8 90 3.22E-15 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS08760 999d520aafa6076faac5831c6f1b6d85 181 Gene3D G3DSA:3.30.70.1060 6 92 1.3E-15 T 28-03-2018 CNX65_RS31195 aaccb415d2ee5af38c37f7541cee3662 377 Pfam PF00534 Glycosyl transferases group 1 194 345 2.0E-19 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS31195 aaccb415d2ee5af38c37f7541cee3662 377 Pfam PF13439 Glycosyltransferase Family 4 13 173 1.8E-20 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS31195 aaccb415d2ee5af38c37f7541cee3662 377 Gene3D G3DSA:3.40.50.2000 153 362 5.3E-37 T 28-03-2018 CNX65_RS31195 aaccb415d2ee5af38c37f7541cee3662 377 SUPERFAMILY SSF53756 8 368 1.3E-64 T 28-03-2018 CNX65_RS18695 73c40051a6bd1442aec222c4eacef7d8 213 Gene3D G3DSA:1.10.510.10 71 177 4.5E-8 T 28-03-2018 CNX65_RS18695 73c40051a6bd1442aec222c4eacef7d8 213 Gene3D G3DSA:3.30.200.20 1 70 5.6E-5 T 28-03-2018 CNX65_RS18695 73c40051a6bd1442aec222c4eacef7d8 213 Pfam PF01636 Phosphotransferase enzyme family 2 99 3.0E-10 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS18695 73c40051a6bd1442aec222c4eacef7d8 213 SUPERFAMILY SSF56112 3 173 3.01E-21 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS35030 45f6068b39c3e3769c59e0579bf6b932 438 Gene3D G3DSA:3.40.640.10 62 314 2.8E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS35030 45f6068b39c3e3769c59e0579bf6b932 438 Pfam PF00155 Aminotransferase class I and II 73 405 3.1E-34 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS35030 45f6068b39c3e3769c59e0579bf6b932 438 Gene3D G3DSA:3.90.1150.10 315 413 8.8E-30 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS35030 45f6068b39c3e3769c59e0579bf6b932 438 SUPERFAMILY SSF53383 21 411 7.98E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS01740 aec733b7e5d3e77793d06f724759dc47 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 3 70 1.8E-15 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CNX65_RS01740 aec733b7e5d3e77793d06f724759dc47 103 Gene3D G3DSA:3.30.70.100 1 102 3.1E-27 T 28-03-2018 CNX65_RS01740 aec733b7e5d3e77793d06f724759dc47 103 SUPERFAMILY SSF54909 1 96 6.19E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS33815 691cde311796ab07b5a2ed2bf8f7891a 387 Pfam PF07690 Major Facilitator Superfamily 14 338 2.2E-33 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS33815 691cde311796ab07b5a2ed2bf8f7891a 387 Gene3D G3DSA:1.20.1250.20 190 379 2.2E-18 T 28-03-2018 CNX65_RS33815 691cde311796ab07b5a2ed2bf8f7891a 387 SUPERFAMILY SSF103473 2 374 4.71E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS33815 691cde311796ab07b5a2ed2bf8f7891a 387 Gene3D G3DSA:1.20.1250.20 1 184 6.7E-24 T 28-03-2018 CNX65_RS04105 e8efb0a6eeb7ba1d3c6b8b3eed53b2c8 344 SUPERFAMILY SSF55486 162 312 4.05E-18 T 28-03-2018 CNX65_RS04105 e8efb0a6eeb7ba1d3c6b8b3eed53b2c8 344 Pfam PF11350 Protein of unknown function (DUF3152) 134 340 6.4E-71 T 28-03-2018 IPR022603 Domain of unknown function DUF3152 CNX65_RS04105 e8efb0a6eeb7ba1d3c6b8b3eed53b2c8 344 Gene3D G3DSA:3.40.390.10 170 325 7.6E-8 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CNX65_RS09970 4cd9c0f6623f3eaa5dea99480e26df1e 531 Gene3D G3DSA:3.40.50.2000 61 328 9.1E-40 T 28-03-2018 CNX65_RS09970 4cd9c0f6623f3eaa5dea99480e26df1e 531 SUPERFAMILY SSF53756 91 528 5.08E-63 T 28-03-2018 CNX65_RS09970 4cd9c0f6623f3eaa5dea99480e26df1e 531 Pfam PF00982 Glycosyltransferase family 20 106 528 3.3E-55 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CNX65_RS09970 4cd9c0f6623f3eaa5dea99480e26df1e 531 Gene3D G3DSA:3.40.50.2000 329 512 1.9E-18 T 28-03-2018 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 PIRSF PIRSF002144 1 93 1.4E-30 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 1.2E-47 T 28-03-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 SUPERFAMILY SSF54570 3 83 3.14E-35 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.078 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 Pfam PF00203 Ribosomal protein S19 3 83 3.4E-36 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 4.5E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 4.5E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 4.5E-24 T 28-03-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 28-03-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32430 a78ad6e26386c91a3df7701344717079 93 Gene3D G3DSA:3.30.860.10 1 92 2.0E-39 T 28-03-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 Pfam PF00356 Bacterial regulatory proteins, lacI family 1 45 4.1E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 SMART SM00354 1 68 2.4E-22 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 Gene3D G3DSA:3.40.50.2300 172 326 4.5E-47 T 28-03-2018 CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 Gene3D G3DSA:1.10.260.40 1 51 1.1E-20 T 28-03-2018 CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 Pfam PF13377 Periplasmic binding protein-like domain 165 323 4.0E-38 T 28-03-2018 CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 SUPERFAMILY SSF47413 1 54 2.89E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 SUPERFAMILY SSF53822 57 327 5.8E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS13075 ad195f3b69ee2b12b64e182ff2782950 328 Gene3D G3DSA:3.40.50.2300 52 171 6.1E-21 T 28-03-2018 CNX65_RS13175 beef8537ef7f73df7e612c6e319ad689 212 Pfam PF01323 DSBA-like thioredoxin domain 7 206 5.3E-40 T 28-03-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590 CNX65_RS13175 beef8537ef7f73df7e612c6e319ad689 212 SUPERFAMILY SSF52833 6 211 2.58E-43 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS13175 beef8537ef7f73df7e612c6e319ad689 212 Gene3D G3DSA:3.40.30.10 3 211 2.5E-52 T 28-03-2018 CNX65_RS20960 dff17779625748a67c9638c869bbbdd5 312 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 162 190 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS20960 dff17779625748a67c9638c869bbbdd5 312 Pfam PF00106 short chain dehydrogenase 17 215 9.1E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20960 dff17779625748a67c9638c869bbbdd5 312 SUPERFAMILY SSF51735 12 260 2.22E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20960 dff17779625748a67c9638c869bbbdd5 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 5.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20960 dff17779625748a67c9638c869bbbdd5 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 92 103 5.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20960 dff17779625748a67c9638c869bbbdd5 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 198 215 5.4E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20960 dff17779625748a67c9638c869bbbdd5 312 Gene3D G3DSA:3.40.50.720 3 311 1.3E-50 T 28-03-2018 CNX65_RS03395 99d34fc425ad3bb1167da9fd93e11ae0 287 SUPERFAMILY SSF52141 59 272 5.23E-42 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS03395 99d34fc425ad3bb1167da9fd93e11ae0 287 Gene3D G3DSA:3.40.470.10 48 277 5.2E-54 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS03395 99d34fc425ad3bb1167da9fd93e11ae0 287 Pfam PF03167 Uracil DNA glycosylase superfamily 91 266 1.7E-24 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS03395 99d34fc425ad3bb1167da9fd93e11ae0 287 SMART SM00987 91 268 3.0E-30 T 28-03-2018 CNX65_RS03395 99d34fc425ad3bb1167da9fd93e11ae0 287 SMART SM00986 91 268 3.0E-30 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Pfam PF13549 ATP-grasp domain 666 871 1.8E-56 T 28-03-2018 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Pfam PF00583 Acetyltransferase (GNAT) family 55 155 2.3E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Gene3D G3DSA:3.40.630.30 12 195 3.3E-27 T 28-03-2018 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Gene3D G3DSA:3.30.1490.20 687 742 3.1E-15 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Gene3D G3DSA:3.40.50.261 479 686 3.0E-27 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 SUPERFAMILY SSF56059 667 866 2.87E-23 T 28-03-2018 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Gene3D G3DSA:3.40.50.720 196 317 7.2E-43 T 28-03-2018 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Gene3D G3DSA:3.30.470.20 743 875 7.2E-33 T 28-03-2018 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 SUPERFAMILY SSF55729 24 161 1.08E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 SUPERFAMILY SSF52210 485 635 1.28E-20 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Gene3D G3DSA:3.40.50.261 318 478 1.8E-43 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 345 478 9.9E-45 T 28-03-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 SUPERFAMILY SSF51735 192 328 4.27E-34 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 SMART SM00881 197 292 9.1E-35 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 SUPERFAMILY SSF52210 323 482 4.06E-37 T 28-03-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 CNX65_RS07285 d3a2e309f30410ab02abd3294c6475e3 892 Pfam PF13380 CoA binding domain 201 327 6.5E-23 T 28-03-2018 IPR003781 CoA-binding GO:0048037 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Gene3D G3DSA:1.50.10.20 52 177 1.3E-20 T 28-03-2018 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Gene3D G3DSA:1.50.10.20 313 419 1.3E-16 T 28-03-2018 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Gene3D G3DSA:1.50.10.20 420 560 2.7E-31 T 28-03-2018 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 SUPERFAMILY SSF48239 48 238 3.66E-22 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 SUPERFAMILY SSF48239 273 555 4.12E-43 T 28-03-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 355 375 0.5 T 28-03-2018 IPR001330 PFTB repeat GO:0003824 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 391 526 3.7E-16 T 28-03-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Pfam PF13249 Squalene-hopene cyclase N-terminal domain 20 168 2.6E-8 T 28-03-2018 IPR032697 Squalene cyclase, N-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Gene3D G3DSA:1.50.10.20 203 312 9.8E-7 T 28-03-2018 CNX65_RS21965 647ee7a67401ee2bb398880638bcead6 560 Gene3D G3DSA:1.50.10.20 3 51 0.03 T 28-03-2018 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 Gene3D G3DSA:1.10.40.30 415 464 4.3E-23 T 28-03-2018 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 SUPERFAMILY SSF48557 6 459 1.73E-138 T 28-03-2018 IPR008948 L-Aspartase-like GO:0003824 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 PRINTS PR00149 Fumarate lyase superfamily signature 267 294 5.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 PRINTS PR00149 Fumarate lyase superfamily signature 130 148 5.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 PRINTS PR00149 Fumarate lyase superfamily signature 313 329 5.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 PRINTS PR00149 Fumarate lyase superfamily signature 176 194 5.0E-29 T 28-03-2018 IPR000362 Fumarate lyase family CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 Hamap MF_00743 Fumarate hydratase class II [fumC]. 6 462 78.785 T 28-03-2018 IPR005677 Fumarate hydratase, class II GO:0004333|GO:0006106|GO:0045239 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 Gene3D G3DSA:1.10.275.10 4 134 6.7E-54 T 28-03-2018 IPR024083 Fumarase/histidase, N-terminal CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 ProSitePatterns PS00163 Fumarate lyases signature. 313 322 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 PRINTS PR00145 Argininosuccinate lyase family signature 129 151 4.0E-6 T 28-03-2018 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 PRINTS PR00145 Argininosuccinate lyase family signature 171 191 4.0E-6 T 28-03-2018 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 PRINTS PR00145 Argininosuccinate lyase family signature 313 329 4.0E-6 T 28-03-2018 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 Pfam PF10415 Fumarase C C-terminus 404 460 7.3E-21 T 28-03-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 Gene3D G3DSA:1.20.200.10 135 414 2.9E-77 T 28-03-2018 CNX65_RS03585 8dffddbe7df910be973a295d65c16db9 464 Pfam PF00206 Lyase 14 338 1.1E-94 T 28-03-2018 IPR022761 Fumarate lyase, N-terminal CNX65_RS02895 a6263a451351e6dc5ea57dacd8a02dd2 410 SUPERFAMILY SSF53955 43 203 2.11E-31 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS02895 a6263a451351e6dc5ea57dacd8a02dd2 410 Gene3D G3DSA:1.10.530.10 44 332 4.6E-25 T 28-03-2018 CNX65_RS02895 a6263a451351e6dc5ea57dacd8a02dd2 410 Pfam PF13406 Transglycosylase SLT domain 122 169 3.7E-7 T 28-03-2018 IPR031304 Transglycosylase SLT domain 2 CNX65_RS12920 5919c62216e8424f6ab98d952fdcba6f 304 Pfam PF02628 Cytochrome oxidase assembly protein 16 283 9.9E-16 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CNX65_RS27485 5b7c8e530b8a3d7227484fd959d4b894 173 Gene3D G3DSA:2.40.380.10 2 165 1.5E-25 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS27485 5b7c8e530b8a3d7227484fd959d4b894 173 SUPERFAMILY SSF159234 7 168 4.45E-32 T 28-03-2018 IPR007295 Domain of unknown function DUF402 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 2 15 4.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 46 4.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 Gene3D G3DSA:1.10.10.60 1 28 1.9E-11 T 28-03-2018 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 Pfam PF00440 Bacterial regulatory proteins, tetR family 2 48 1.1E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 Gene3D G3DSA:1.10.357.10 58 206 2.8E-25 T 28-03-2018 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 Gene3D G3DSA:1.10.260.40 29 57 4.2E-8 T 28-03-2018 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 SUPERFAMILY SSF46689 2 53 1.41E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 SUPERFAMILY SSF48498 67 203 5.93E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS20300 098fd57c0abce966a2a9cc103b8e9f22 209 Pfam PF02909 Tetracyclin repressor, C-terminal all-alpha domain 67 196 4.3E-9 T 28-03-2018 IPR004111 Tetracycline transcriptional regulator, TetR, C-terminal GO:0045892 CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 Gene3D G3DSA:1.10.3210.10 18 202 5.9E-60 T 28-03-2018 CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 Gene3D G3DSA:1.10.3410.10 203 341 2.4E-26 T 28-03-2018 IPR023293 Deoxyguanosinetriphosphate triphosphohydrolase, central domain CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 Pfam PF13286 Phosphohydrolase-associated domain 321 411 1.1E-21 T 28-03-2018 IPR026875 Phosphohydrolase-associated domain CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 TIGRFAM TIGR01353 dGTP_triPase: putative dGTPase 31 411 2.5E-76 T 28-03-2018 IPR006261 dNTP triphosphohydrolase GO:0016793 CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 SUPERFAMILY SSF109604 30 230 4.32E-54 T 28-03-2018 CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 Pfam PF01966 HD domain 72 211 1.6E-20 T 28-03-2018 IPR006674 HD domain CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 SMART SM00471 68 221 1.4E-12 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS06325 c3104c93b4165f34b81f44109e7eeecf 417 Hamap MF_01212 Deoxyguanosinetriphosphate triphosphohydrolase-like protein. 5 414 30.052 T 28-03-2018 IPR023023 dNTP triphosphohydrolase, type 2 GO:0016793 CNX65_RS09450 266a27f5121cc6fb0d30947fa933b2d9 137 Gene3D G3DSA:3.30.300.20 2 129 9.6E-21 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS09450 266a27f5121cc6fb0d30947fa933b2d9 137 SUPERFAMILY SSF82784 24 128 9.68E-19 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS09450 266a27f5121cc6fb0d30947fa933b2d9 137 Pfam PF02566 OsmC-like protein 43 128 9.4E-12 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS29870 f8b0bd09ac7b7da98ba5c3e62fb646b5 128 Gene3D G3DSA:3.40.250.10 1 127 1.0E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS29870 f8b0bd09ac7b7da98ba5c3e62fb646b5 128 SMART SM00450 1 118 3.8E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS29870 f8b0bd09ac7b7da98ba5c3e62fb646b5 128 SUPERFAMILY SSF52821 26 123 1.83E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS29870 f8b0bd09ac7b7da98ba5c3e62fb646b5 128 Pfam PF00581 Rhodanese-like domain 27 114 4.9E-8 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS05890 84fdc2b811d3a1552ef626bc99d9cd35 298 SUPERFAMILY SSF143631 2 283 1.2E-56 T 28-03-2018 IPR003374 ApbE-like domain CNX65_RS05890 84fdc2b811d3a1552ef626bc99d9cd35 298 Gene3D G3DSA:3.10.520.10 4 291 9.5E-31 T 28-03-2018 CNX65_RS05890 84fdc2b811d3a1552ef626bc99d9cd35 298 Pfam PF02424 ApbE family 8 274 3.0E-49 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 SUPERFAMILY SSF117074 55 133 2.48E-12 T 28-03-2018 CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 Pfam PF00652 Ricin-type beta-trefoil lectin domain 182 273 9.8E-9 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 SUPERFAMILY SSF50370 183 318 2.34E-21 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 Gene3D G3DSA:2.80.10.50 181 281 2.6E-12 T 28-03-2018 CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 Gene3D G3DSA:2.80.10.50 282 319 1.5E-7 T 28-03-2018 CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 Gene3D G3DSA:2.60.40.10 56 180 2.5E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 SMART SM00458 180 319 6.2E-6 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS20750 c3a7666467f46774aa41a832e27490a4 319 Pfam PF17210 SdrD B-like domain 61 173 6.2E-15 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS30520 c8b7c2f3c3992410397cf8062e9beab4 318 Gene3D G3DSA:3.40.50.720 148 234 1.0E-13 T 28-03-2018 CNX65_RS30520 c8b7c2f3c3992410397cf8062e9beab4 318 Pfam PF13602 Zinc-binding dehydrogenase 188 312 9.3E-21 T 28-03-2018 CNX65_RS30520 c8b7c2f3c3992410397cf8062e9beab4 318 SUPERFAMILY SSF51735 117 291 2.33E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30520 c8b7c2f3c3992410397cf8062e9beab4 318 Gene3D G3DSA:3.90.180.10 1 147 2.3E-40 T 28-03-2018 CNX65_RS30520 c8b7c2f3c3992410397cf8062e9beab4 318 SMART SM00829 10 314 3.4E-12 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS30520 c8b7c2f3c3992410397cf8062e9beab4 318 Gene3D G3DSA:3.90.180.10 235 318 2.5E-7 T 28-03-2018 CNX65_RS30520 c8b7c2f3c3992410397cf8062e9beab4 318 SUPERFAMILY SSF50129 2 149 2.28E-31 T 28-03-2018 IPR011032 GroES-like CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 Gene3D G3DSA:3.30.2350.10 70 250 1.5E-41 T 28-03-2018 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 Pfam PF00849 RNA pseudouridylate synthase 76 207 1.3E-22 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 Pfam PF01479 S4 domain 13 56 2.3E-12 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 79 237 1.0E-42 T 28-03-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 SUPERFAMILY SSF55174 10 69 2.35E-12 T 28-03-2018 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 112 126 - T 28-03-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 Gene3D G3DSA:3.10.290.10 7 69 3.9E-16 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 SUPERFAMILY SSF55120 61 248 2.16E-45 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS27010 eb6ff08d253a74af83265e3bfe7d1658 250 SMART SM00363 13 74 2.6E-10 T 28-03-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-6791226 CNX65_RS30370 a7c13a25bdfd7c7e63e0ca69c6b4348e 289 SUPERFAMILY SSF53474 3 289 4.09E-63 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30370 a7c13a25bdfd7c7e63e0ca69c6b4348e 289 Gene3D G3DSA:3.40.50.1820 2 289 5.3E-44 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30370 a7c13a25bdfd7c7e63e0ca69c6b4348e 289 Pfam PF00561 alpha/beta hydrolase fold 29 139 4.0E-19 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS09250 6d3f529c74dbcaa8d98ccc7c7985c344 332 Gene3D G3DSA:1.10.3470.10 21 325 4.2E-31 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS09250 6d3f529c74dbcaa8d98ccc7c7985c344 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 319 4.1E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS33920 995483a0de0e2df3a6373b4c0366dbe8 650 SUPERFAMILY SSF53474 317 484 2.64E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS33920 995483a0de0e2df3a6373b4c0366dbe8 650 Gene3D G3DSA:1.10.287.700 569 649 0.0049 T 28-03-2018 CNX65_RS33920 995483a0de0e2df3a6373b4c0366dbe8 650 Gene3D G3DSA:1.10.287.850 12 103 6.8E-4 T 28-03-2018 CNX65_RS33920 995483a0de0e2df3a6373b4c0366dbe8 650 Gene3D G3DSA:3.40.50.1820 310 568 2.5E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS33920 995483a0de0e2df3a6373b4c0366dbe8 650 Pfam PF06259 Alpha/beta hydrolase 322 482 5.9E-28 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 SUPERFAMILY SSF51735 11 259 1.0E-62 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 17 256 3.3E-49 T 28-03-2018 CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 147 155 1.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 167 186 1.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 85 96 1.5E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 154 182 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 8.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 188 205 8.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 85 96 8.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 157 8.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 8.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 167 186 8.7E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12190 44ea08ca288523df99d329f9fd8547e9 261 Gene3D G3DSA:3.40.50.720 5 261 4.9E-59 T 28-03-2018 CNX65_RS33210 d287b6edbb336eedde8e1d5dfa99c725 331 SUPERFAMILY SSF69593 92 322 1.19E-31 T 28-03-2018 CNX65_RS33210 d287b6edbb336eedde8e1d5dfa99c725 331 SMART SM00563 117 236 3.8E-12 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS33210 d287b6edbb336eedde8e1d5dfa99c725 331 Pfam PF01553 Acyltransferase 103 233 2.6E-13 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS33210 d287b6edbb336eedde8e1d5dfa99c725 331 Gene3D G3DSA:3.40.1130.10 78 328 6.6E-24 T 28-03-2018 CNX65_RS33210 d287b6edbb336eedde8e1d5dfa99c725 331 PIRSF PIRSF016753 32 331 2.8E-94 T 28-03-2018 IPR016676 Phospholipid/glycerol acyltransferase, predicted CNX65_RS16900 a690053f19cac0dc8b02509eb7e661b1 219 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 179 219 1.3E-15 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS16900 a690053f19cac0dc8b02509eb7e661b1 219 PIRSF PIRSF000190 2 219 8.9E-60 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS16900 a690053f19cac0dc8b02509eb7e661b1 219 Gene3D G3DSA:2.30.110.10 22 219 4.3E-58 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS16900 a690053f19cac0dc8b02509eb7e661b1 219 SUPERFAMILY SSF50475 25 219 1.87E-56 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS16900 a690053f19cac0dc8b02509eb7e661b1 219 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 30 219 7.8E-50 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS16900 a690053f19cac0dc8b02509eb7e661b1 219 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 43 126 6.9E-17 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS07825 501a0be09574ac1997d9cf9bef4d3725 301 SUPERFAMILY SSF103481 65 157 8.5E-6 T 28-03-2018 CNX65_RS07825 501a0be09574ac1997d9cf9bef4d3725 301 SUPERFAMILY SSF103481 199 298 6.41E-11 T 28-03-2018 CNX65_RS07825 501a0be09574ac1997d9cf9bef4d3725 301 Pfam PF00892 EamA-like transporter family 164 293 2.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS08470 7f469f370bd25833c098804c0afec6c7 163 Gene3D G3DSA:3.40.50.2020 1 162 1.3E-31 T 28-03-2018 CNX65_RS08470 7f469f370bd25833c098804c0afec6c7 163 Pfam PF00156 Phosphoribosyl transferase domain 25 133 1.4E-7 T 28-03-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 CNX65_RS08470 7f469f370bd25833c098804c0afec6c7 163 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 1 163 30.491 T 28-03-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 CNX65_RS08470 7f469f370bd25833c098804c0afec6c7 163 SUPERFAMILY SSF53271 2 159 8.8E-42 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS29175 6ae02b3b87bca7d2e3b3122f97606616 257 SMART SM00346 15 102 1.1E-21 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS29175 6ae02b3b87bca7d2e3b3122f97606616 257 Pfam PF01614 Bacterial transcriptional regulator 130 249 9.0E-27 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS29175 6ae02b3b87bca7d2e3b3122f97606616 257 Pfam PF09339 IclR helix-turn-helix domain 17 67 6.0E-18 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS29175 6ae02b3b87bca7d2e3b3122f97606616 257 SUPERFAMILY SSF46785 15 86 2.61E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29175 6ae02b3b87bca7d2e3b3122f97606616 257 SUPERFAMILY SSF55781 72 251 1.31E-46 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS29175 6ae02b3b87bca7d2e3b3122f97606616 257 Gene3D G3DSA:3.30.450.40 87 255 3.4E-47 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS29175 6ae02b3b87bca7d2e3b3122f97606616 257 Gene3D G3DSA:1.10.10.10 3 75 6.9E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29400 449a8bd044ec87d21384ad6325e0aaae 175 Gene3D G3DSA:3.40.630.30 2 162 4.6E-24 T 28-03-2018 CNX65_RS29400 449a8bd044ec87d21384ad6325e0aaae 175 Pfam PF00583 Acetyltransferase (GNAT) family 38 134 8.5E-12 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS29400 449a8bd044ec87d21384ad6325e0aaae 175 SUPERFAMILY SSF55729 9 145 4.12E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS07890 9d24ed585b9f79892a4dd49e3eaffce6 294 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 58 200 6.0E-44 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS07890 9d24ed585b9f79892a4dd49e3eaffce6 294 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 58 201 3.8E-39 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS17500 cbb0f222e62d241d14cb63ada3b7b92a 193 SUPERFAMILY SSF53597 3 192 2.13E-19 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS17500 cbb0f222e62d241d14cb63ada3b7b92a 193 Pfam PF01872 RibD C-terminal domain 112 170 1.4E-6 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS17500 cbb0f222e62d241d14cb63ada3b7b92a 193 Gene3D G3DSA:3.40.430.10 2 193 6.8E-29 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS16710 16522f7c5f35b21b82c39b6825f53728 126 Pfam PF07883 Cupin domain 38 91 5.6E-10 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CNX65_RS16710 16522f7c5f35b21b82c39b6825f53728 126 SUPERFAMILY SSF51182 5 111 5.0E-18 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS16710 16522f7c5f35b21b82c39b6825f53728 126 Gene3D G3DSA:2.60.120.10 1 110 1.3E-16 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS25710 fc0d0713949838adf2b49f1663fd46fc 152 SMART SM00418 28 102 0.0041 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS25710 fc0d0713949838adf2b49f1663fd46fc 152 Pfam PF01022 Bacterial regulatory protein, arsR family 37 75 1.1E-6 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS25710 fc0d0713949838adf2b49f1663fd46fc 152 Gene3D G3DSA:1.10.10.10 5 149 1.7E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25710 fc0d0713949838adf2b49f1663fd46fc 152 SUPERFAMILY SSF46785 31 106 1.69E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15595 ef7d76240b8f734f3197df87aaae1353 223 Pfam PF00005 ABC transporter 21 165 5.5E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS15595 ef7d76240b8f734f3197df87aaae1353 223 SUPERFAMILY SSF52540 3 212 1.48E-45 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15595 ef7d76240b8f734f3197df87aaae1353 223 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS15595 ef7d76240b8f734f3197df87aaae1353 223 SMART SM00382 29 215 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15595 ef7d76240b8f734f3197df87aaae1353 223 Gene3D G3DSA:3.40.50.300 1 222 6.0E-46 T 28-03-2018 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 Gene3D G3DSA:1.10.940.10 33 175 3.3E-27 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 SUPERFAMILY SSF53335 179 476 3.19E-50 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 Pfam PF01189 16S rRNA methyltransferase RsmB/F 290 474 1.7E-46 T 28-03-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 Gene3D G3DSA:3.40.50.150 271 478 1.9E-44 T 28-03-2018 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 SUPERFAMILY SSF48013 36 190 1.64E-31 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 Pfam PF01029 NusB family 36 157 1.4E-23 T 28-03-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 295 305 1.1E-18 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 262 276 1.1E-18 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 408 424 1.1E-18 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 459 476 1.1E-18 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CNX65_RS25990 6815524fde73f5e988f4a5bdea94981d 478 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 358 370 1.1E-18 T 28-03-2018 IPR023267 RNA (C5-cytosine) methyltransferase KEGG: 00564+2.1.1.17|MetaCyc: PWY-6825 CNX65_RS05935 1b5d745b506c41cf03ea6170b134850e 426 ProSitePatterns PS00216 Sugar transport proteins signature 1. 299 316 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS05935 1b5d745b506c41cf03ea6170b134850e 426 Gene3D G3DSA:1.20.1250.20 11 219 3.2E-27 T 28-03-2018 CNX65_RS05935 1b5d745b506c41cf03ea6170b134850e 426 Gene3D G3DSA:1.20.1250.20 225 426 3.3E-22 T 28-03-2018 CNX65_RS05935 1b5d745b506c41cf03ea6170b134850e 426 SUPERFAMILY SSF103473 18 418 3.53E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS05935 1b5d745b506c41cf03ea6170b134850e 426 Pfam PF07690 Major Facilitator Superfamily 30 385 5.9E-31 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 PIRSF PIRSF001467 4 182 6.8E-59 T 28-03-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 SUPERFAMILY SSF50891 14 179 2.48E-62 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 16 178 4.1E-46 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 Gene3D G3DSA:2.40.100.10 2 182 6.7E-65 T 28-03-2018 IPR029000 Cyclophilin-like domain CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 64 81 - T 28-03-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 28 43 1.3E-27 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 124 136 1.3E-27 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 137 152 1.3E-27 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 69 81 1.3E-27 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS00070 6334b83891d86a5b6241bdb8cd6612b4 182 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 109 124 1.3E-27 T 28-03-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755|GO:0006457 CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 SUPERFAMILY SSF53613 2 286 8.11E-54 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 PIRSF PIRSF000535 1 297 9.9E-65 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 Gene3D G3DSA:3.40.1190.20 42 291 3.5E-36 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 Gene3D G3DSA:2.20.150.10 9 41 4.3E-14 T 28-03-2018 IPR023314 Tagatose-6-phosphate kinase/1-phosphofructokinase N-terminal domain CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 PRINTS PR00990 Ribokinase signature 31 50 3.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 PRINTS PR00990 Ribokinase signature 167 182 3.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 PRINTS PR00990 Ribokinase signature 211 222 3.3E-6 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 288 7.4E-87 T 28-03-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 Pfam PF00294 pfkB family carbohydrate kinase 22 283 3.7E-37 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS05330 b43949f10d11475981df932f19f96f48 308 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 240 253 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS19985 4e11fa0af89de5e10023f2366620f262 246 Gene3D G3DSA:3.40.50.720 1 240 8.1E-14 T 28-03-2018 CNX65_RS19985 4e11fa0af89de5e10023f2366620f262 246 SUPERFAMILY SSF51735 1 204 8.05E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19985 4e11fa0af89de5e10023f2366620f262 246 Pfam PF13460 NAD(P)H-binding 7 172 9.0E-11 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00305 7a32c34909e0999f7ca44f920ed3cbfd 354 SUPERFAMILY SSF53335 57 165 1.98E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS00305 7a32c34909e0999f7ca44f920ed3cbfd 354 Pfam PF08241 Methyltransferase domain 63 159 1.4E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS00305 7a32c34909e0999f7ca44f920ed3cbfd 354 Gene3D G3DSA:3.40.50.150 43 224 1.6E-29 T 28-03-2018 CNX65_RS27730 3564ac9f17eca067bf7f67895972c642 100 TIGRFAM TIGR03954 integ_memb_HG: integral membrane protein 8 90 8.6E-31 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CNX65_RS27730 3564ac9f17eca067bf7f67895972c642 100 Pfam PF12823 Domain of unknown function (DUF3817) 5 90 1.5E-27 T 28-03-2018 IPR023845 Domain of unknown function DUF3817, transmembrane CNX65_RS35080 a7cafe7569771a74b4c793799d23e6f7 47 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 4 47 15.563 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS35080 a7cafe7569771a74b4c793799d23e6f7 47 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 5 47 4.8E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS35080 a7cafe7569771a74b4c793799d23e6f7 47 ProSitePatterns PS00784 Ribosomal protein L34 signature. 5 24 - T 28-03-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS35080 a7cafe7569771a74b4c793799d23e6f7 47 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 5 45 1.0E-13 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS35080 a7cafe7569771a74b4c793799d23e6f7 47 Pfam PF00468 Ribosomal protein L34 5 47 2.5E-20 T 28-03-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS11380 37bac3183f68d0f4926db6b21d9b1447 172 ProSitePatterns PS00893 Nudix box signature. 66 87 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS11380 37bac3183f68d0f4926db6b21d9b1447 172 Gene3D G3DSA:3.90.79.10 1 169 1.0E-34 T 28-03-2018 CNX65_RS11380 37bac3183f68d0f4926db6b21d9b1447 172 PIRSF PIRSF017340 1 165 1.1E-49 T 28-03-2018 IPR024195 NUDIX hydrolase, YfcD, predicted GO:0016817 CNX65_RS11380 37bac3183f68d0f4926db6b21d9b1447 172 Pfam PF00293 NUDIX domain 29 150 4.0E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS11380 37bac3183f68d0f4926db6b21d9b1447 172 SUPERFAMILY SSF55811 2 162 7.72E-37 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 335 160.461 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 Gene3D G3DSA:1.10.8.60 180 250 2.3E-30 T 28-03-2018 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 20 322 6.8E-137 T 28-03-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 SUPERFAMILY SSF46785 252 326 5.01E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 249 322 7.9E-30 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 Gene3D G3DSA:3.40.50.300 14 177 3.4E-25 T 28-03-2018 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 231 6.8E-107 T 28-03-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 SMART SM00382 47 180 3.7E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 SUPERFAMILY SSF52540 16 246 9.94E-50 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 249 323 2.0E-23 T 28-03-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 CNX65_RS08430 dcb85c0cac3636ceebc09a7f146e8a79 335 Gene3D G3DSA:1.10.10.10 253 323 8.7E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02010 25c559a968ce07b5fb74eb8e83174376 313 SUPERFAMILY SSF53067 117 298 2.59E-28 T 28-03-2018 CNX65_RS02010 25c559a968ce07b5fb74eb8e83174376 313 Gene3D G3DSA:3.30.420.40 130 277 4.0E-33 T 28-03-2018 CNX65_RS02010 25c559a968ce07b5fb74eb8e83174376 313 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 294 8.2E-20 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CNX65_RS02010 25c559a968ce07b5fb74eb8e83174376 313 Gene3D G3DSA:3.30.420.40 1 129 5.9E-13 T 28-03-2018 CNX65_RS02010 25c559a968ce07b5fb74eb8e83174376 313 SUPERFAMILY SSF53067 1 113 8.2E-14 T 28-03-2018 CNX65_RS16300 1ca90cc94fc69a03fff8102122faf6d5 402 Pfam PF00201 UDP-glucoronosyl and UDP-glucosyl transferase 282 365 1.4E-17 T 28-03-2018 IPR002213 UDP-glucuronosyl/UDP-glucosyltransferase GO:0008152|GO:0016758 Reactome: R-HSA-156588 CNX65_RS16300 1ca90cc94fc69a03fff8102122faf6d5 402 SUPERFAMILY SSF53756 2 394 6.06E-60 T 28-03-2018 CNX65_RS16300 1ca90cc94fc69a03fff8102122faf6d5 402 Gene3D G3DSA:3.40.50.2000 1 201 8.5E-20 T 28-03-2018 CNX65_RS16300 1ca90cc94fc69a03fff8102122faf6d5 402 Gene3D G3DSA:3.40.50.2000 202 377 1.4E-37 T 28-03-2018 CNX65_RS09570 f791f4d90f2dda36b15cfb662f471951 98 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 18 97 7.5E-5 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS09570 f791f4d90f2dda36b15cfb662f471951 98 SUPERFAMILY SSF69754 18 96 1.57E-9 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS09570 f791f4d90f2dda36b15cfb662f471951 98 Gene3D G3DSA:3.30.160.100 8 98 1.5E-6 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS23230 43703a22264771e2f271722bff394801 244 SUPERFAMILY SSF51197 26 144 1.19E-5 T 28-03-2018 CNX65_RS23230 43703a22264771e2f271722bff394801 244 Gene3D G3DSA:2.60.120.620 23 231 1.4E-8 T 28-03-2018 CNX65_RS33945 73701d87c410728f381b377f720dd83a 130 Gene3D G3DSA:1.10.287.1060 8 130 2.1E-4 T 28-03-2018 CNX65_RS26625 8584b7cbd71a810d4b1d9323517f7f5b 587 SMART SM00220 1 247 2.1E-32 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS26625 8584b7cbd71a810d4b1d9323517f7f5b 587 Gene3D G3DSA:1.10.510.10 1 253 2.9E-50 T 28-03-2018 CNX65_RS26625 8584b7cbd71a810d4b1d9323517f7f5b 587 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 5 27 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS26625 8584b7cbd71a810d4b1d9323517f7f5b 587 Pfam PF00069 Protein kinase domain 4 243 1.1E-31 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS26625 8584b7cbd71a810d4b1d9323517f7f5b 587 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 116 128 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS26625 8584b7cbd71a810d4b1d9323517f7f5b 587 SUPERFAMILY SSF56112 4 249 8.36E-55 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS27415 c24df9c195f542398d79ca1e1bf84f67 362 SUPERFAMILY SSF160424 10 144 3.66E-21 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS08220 a5aa10851f59b33cded779d5c29db137 184 Pfam PF04138 GtrA-like protein 25 155 6.3E-18 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CNX65_RS17120 64db971b2b62107f819196263014b3d0 276 SUPERFAMILY SSF49265 186 273 1.7E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS17120 64db971b2b62107f819196263014b3d0 276 SMART SM00060 189 262 3.9E-4 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS17120 64db971b2b62107f819196263014b3d0 276 Gene3D G3DSA:2.60.40.10 179 269 5.4E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS12715 99ef28cbf207a3eba89441ad4b781345 483 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 249 256 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS12715 99ef28cbf207a3eba89441ad4b781345 483 SUPERFAMILY SSF53720 12 475 9.42E-136 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS12715 99ef28cbf207a3eba89441ad4b781345 483 Gene3D G3DSA:3.40.605.10 8 267 1.3E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS12715 99ef28cbf207a3eba89441ad4b781345 483 Gene3D G3DSA:3.40.309.10 268 456 2.0E-58 T 28-03-2018 CNX65_RS12715 99ef28cbf207a3eba89441ad4b781345 483 Pfam PF00171 Aldehyde dehydrogenase family 18 472 2.6E-136 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS12715 99ef28cbf207a3eba89441ad4b781345 483 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 277 288 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS18380 5569dbc5d0e5cf37c8efb8b32f146680 306 Gene3D G3DSA:3.40.50.970 5 305 4.9E-52 T 28-03-2018 CNX65_RS18380 5569dbc5d0e5cf37c8efb8b32f146680 306 SUPERFAMILY SSF52518 12 298 2.95E-57 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS18380 5569dbc5d0e5cf37c8efb8b32f146680 306 Pfam PF00676 Dehydrogenase E1 component 16 267 3.8E-40 T 28-03-2018 IPR001017 Dehydrogenase, E1 component GO:0008152|GO:0016624 Reactome: R-HSA-389661 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 Gene3D G3DSA:1.10.287.1060 234 311 9.6E-5 T 28-03-2018 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 489 1.4E-31 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 Gene3D G3DSA:1.10.287.950 312 522 8.3E-46 T 28-03-2018 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 SMART SM00283 266 520 3.5E-55 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 SMART SM00304 321 377 100.0 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 SMART SM00304 206 258 8.2E-14 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 SUPERFAMILY SSF58104 226 519 1.19E-63 T 28-03-2018 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 183 203 9.0E-24 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 6 31 9.0E-24 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 364 391 9.0E-24 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 393 422 9.0E-24 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 Pfam PF00672 HAMP domain 206 253 1.8E-11 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS11200 5534b9095b8b285013081c8579328f1c 522 Pfam PF05227 CHASE3 domain 44 161 1.8E-7 T 28-03-2018 IPR007891 CHASE3 CNX65_RS04255 6c755ce65665023e1402661adfd13efb 291 SUPERFAMILY SSF53474 5 287 3.45E-68 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04255 6c755ce65665023e1402661adfd13efb 291 PRINTS PR00412 Epoxide hydrolase signature 230 246 2.5E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04255 6c755ce65665023e1402661adfd13efb 291 PRINTS PR00412 Epoxide hydrolase signature 35 53 2.5E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04255 6c755ce65665023e1402661adfd13efb 291 PRINTS PR00412 Epoxide hydrolase signature 101 114 2.5E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04255 6c755ce65665023e1402661adfd13efb 291 PRINTS PR00412 Epoxide hydrolase signature 262 284 2.5E-7 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS04255 6c755ce65665023e1402661adfd13efb 291 Gene3D G3DSA:3.40.50.1820 5 290 2.0E-52 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04255 6c755ce65665023e1402661adfd13efb 291 Pfam PF00561 alpha/beta hydrolase fold 29 271 7.0E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS30505 d7b954e35d6b50117ebc209ce5323ccc 230 Gene3D G3DSA:1.10.10.60 115 169 7.3E-6 T 28-03-2018 CNX65_RS30505 d7b954e35d6b50117ebc209ce5323ccc 230 Pfam PF12833 Helix-turn-helix domain 138 213 2.7E-13 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS30505 d7b954e35d6b50117ebc209ce5323ccc 230 SMART SM00342 131 213 8.4E-5 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS30505 d7b954e35d6b50117ebc209ce5323ccc 230 Gene3D G3DSA:1.10.10.60 170 217 3.0E-6 T 28-03-2018 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 Pfam PF13802 Galactose mutarotase-like 156 215 1.2E-16 T 28-03-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 Gene3D G3DSA:3.20.20.80 236 602 4.2E-122 T 28-03-2018 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 SUPERFAMILY SSF117125 663 738 1.2E-13 T 28-03-2018 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 SUPERFAMILY SSF51445 245 581 3.1E-94 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 Gene3D G3DSA:2.60.40.1760 1 235 1.9E-54 T 28-03-2018 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 SUPERFAMILY SSF51011 583 661 2.81E-21 T 28-03-2018 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 SUPERFAMILY SSF74650 2 244 6.59E-59 T 28-03-2018 IPR011013 Galactose mutarotase-like domain GO:0003824|GO:0005975|GO:0030246 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 Gene3D G3DSA:2.60.40.1180 663 747 1.5E-17 T 28-03-2018 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 Gene3D G3DSA:2.60.40.1180 603 662 4.3E-19 T 28-03-2018 CNX65_RS15035 5452aedddeffc4614770b08d06370444 749 Pfam PF01055 Glycosyl hydrolases family 31 238 666 3.1E-122 T 28-03-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 Gene3D G3DSA:3.40.190.10 89 173 1.7E-17 T 28-03-2018 CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 Pfam PF03466 LysR substrate binding domain 103 278 1.9E-19 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 Gene3D G3DSA:1.10.10.10 1 88 4.7E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 Gene3D G3DSA:3.40.190.10 174 263 1.8E-11 T 28-03-2018 CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 20 31 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 31 41 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 41 52 2.2E-7 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 SUPERFAMILY SSF53850 96 262 1.86E-16 T 28-03-2018 CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 SUPERFAMILY SSF46785 3 87 5.99E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22175 8b4d11657389aed53fe167edb896a29b 288 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.2E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS01865 42de94cc654240001ce1ae250ec3254b 230 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 225 40.679 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CNX65_RS01865 42de94cc654240001ce1ae250ec3254b 230 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 3 225 5.6E-62 T 28-03-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CNX65_RS01865 42de94cc654240001ce1ae250ec3254b 230 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 105 112 - T 28-03-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CNX65_RS01865 42de94cc654240001ce1ae250ec3254b 230 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 225 7.7E-63 T 28-03-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 CNX65_RS01865 42de94cc654240001ce1ae250ec3254b 230 SUPERFAMILY SSF53448 3 225 7.51E-53 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS01865 42de94cc654240001ce1ae250ec3254b 230 Gene3D G3DSA:3.90.550.10 1 227 3.5E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS29300 f1c680815aa3571963cbfc12b9698d86 238 Gene3D G3DSA:1.20.5.620 147 197 2.4E-4 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS29300 f1c680815aa3571963cbfc12b9698d86 238 Gene3D G3DSA:1.20.5.620 6 79 0.06 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS29300 f1c680815aa3571963cbfc12b9698d86 238 Gene3D G3DSA:1.20.5.620 80 146 4.5E-8 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS10225 eeccb069ca68045d8495672a7a7af22c 69 Pfam PF12728 Helix-turn-helix domain 13 54 2.9E-9 T 28-03-2018 CNX65_RS10225 eeccb069ca68045d8495672a7a7af22c 69 Gene3D G3DSA:1.10.10.10 27 68 4.4E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10225 eeccb069ca68045d8495672a7a7af22c 69 SUPERFAMILY SSF46955 12 54 1.19E-5 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS10225 eeccb069ca68045d8495672a7a7af22c 69 Gene3D G3DSA:1.10.10.60 5 26 3.7E-6 T 28-03-2018 CNX65_RS06240 1690b9702235e205f0e956e97c87a481 110 SUPERFAMILY SSF53927 13 78 1.43E-7 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS06240 1690b9702235e205f0e956e97c87a481 110 Gene3D G3DSA:3.40.140.10 2 106 9.8E-7 T 28-03-2018 CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 SUPERFAMILY SSF46894 124 223 8.22E-31 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 Gene3D G3DSA:1.10.10.10 123 227 5.9E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 Pfam PF00072 Response regulator receiver domain 5 113 3.6E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 SUPERFAMILY SSF52172 2 124 3.27E-40 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 Gene3D G3DSA:3.40.50.2300 1 122 1.3E-37 T 28-03-2018 CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 223 1.4E-28 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 SMART SM00862 147 223 4.5E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS19320 8fe5405951cd1ef359fe430cffc05a61 227 SMART SM00448 3 113 9.4E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS19920 19bd3e3f208ae2af6d8dd551b6d16179 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 51 74 4.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19920 19bd3e3f208ae2af6d8dd551b6d16179 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 43 4.8E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19920 19bd3e3f208ae2af6d8dd551b6d16179 207 Gene3D G3DSA:1.10.357.10 18 203 2.1E-31 T 28-03-2018 CNX65_RS19920 19bd3e3f208ae2af6d8dd551b6d16179 207 SUPERFAMILY SSF48498 102 193 6.67E-8 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS19920 19bd3e3f208ae2af6d8dd551b6d16179 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 30 76 2.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19920 19bd3e3f208ae2af6d8dd551b6d16179 207 SUPERFAMILY SSF46689 18 98 9.23E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14310 3cc0cdba8394ae0553a7d623698c518a 619 Gene3D G3DSA:1.50.10.10 271 437 1.6E-14 T 28-03-2018 CNX65_RS14310 3cc0cdba8394ae0553a7d623698c518a 619 Gene3D G3DSA:1.50.10.10 71 270 2.9E-21 T 28-03-2018 CNX65_RS14310 3cc0cdba8394ae0553a7d623698c518a 619 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 62 563 1.0E-144 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CNX65_RS14310 3cc0cdba8394ae0553a7d623698c518a 619 SUPERFAMILY SSF48208 117 401 6.24E-17 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS01565 f7ed8f1acafabd630e4472b20ea2e72e 148 Gene3D G3DSA:3.10.129.10 1 146 3.1E-18 T 28-03-2018 CNX65_RS01565 f7ed8f1acafabd630e4472b20ea2e72e 148 Pfam PF14539 Domain of unknown function (DUF4442) 5 143 8.0E-23 T 28-03-2018 IPR027961 Protein of unknown function DUF4442 CNX65_RS01565 f7ed8f1acafabd630e4472b20ea2e72e 148 SUPERFAMILY SSF54637 4 146 3.73E-17 T 28-03-2018 IPR029069 HotDog domain CNX65_RS29130 97269a5765546333f6a70ffe368b2879 447 Pfam PF00909 Ammonium Transporter Family 7 417 2.7E-127 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CNX65_RS29130 97269a5765546333f6a70ffe368b2879 447 Gene3D G3DSA:1.10.3430.10 1 398 1.2E-130 T 28-03-2018 CNX65_RS29130 97269a5765546333f6a70ffe368b2879 447 TIGRFAM TIGR00836 amt: ammonium transporter 5 417 1.1E-139 T 28-03-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 CNX65_RS29130 97269a5765546333f6a70ffe368b2879 447 ProSitePatterns PS01219 Ammonium transporters signature. 173 198 - T 28-03-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 CNX65_RS29130 97269a5765546333f6a70ffe368b2879 447 SUPERFAMILY SSF111352 2 397 1.96E-119 T 28-03-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 CNX65_RS19055 7acca07fa168c890c4b04b0c4f175610 361 SUPERFAMILY SSF48576 50 360 8.82E-68 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS19055 7acca07fa168c890c4b04b0c4f175610 361 Pfam PF00348 Polyprenyl synthetase 51 310 1.2E-45 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CNX65_RS19055 7acca07fa168c890c4b04b0c4f175610 361 Gene3D G3DSA:1.10.600.10 12 361 1.4E-79 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS19055 7acca07fa168c890c4b04b0c4f175610 361 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 94 108 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CNX65_RS19055 7acca07fa168c890c4b04b0c4f175610 361 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 238 250 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CNX65_RS29190 3b9e6a3c453a84b6a6ebe891c949e585 376 Pfam PF03702 Anhydro-N-acetylmuramic acid kinase 2 349 2.2E-91 T 28-03-2018 IPR005338 Anhydro-N-acetylmuramic acid kinase GO:0005524|GO:0006040|GO:0009254|GO:0016773 KEGG: 00040+2.7.1.17 CNX65_RS29190 3b9e6a3c453a84b6a6ebe891c949e585 376 SUPERFAMILY SSF53067 3 64 6.66E-14 T 28-03-2018 CNX65_RS29190 3b9e6a3c453a84b6a6ebe891c949e585 376 SUPERFAMILY SSF53067 128 311 6.66E-14 T 28-03-2018 CNX65_RS29190 3b9e6a3c453a84b6a6ebe891c949e585 376 Gene3D G3DSA:3.30.420.40 221 356 1.6E-23 T 28-03-2018 CNX65_RS29190 3b9e6a3c453a84b6a6ebe891c949e585 376 Gene3D G3DSA:3.30.420.40 1 176 2.7E-32 T 28-03-2018 CNX65_RS31610 b4a42d797b59cc1b594b3f58c660b3e3 860 Gene3D G3DSA:3.30.1310.10 3 87 5.7E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS31610 b4a42d797b59cc1b594b3f58c660b3e3 860 Gene3D G3DSA:3.40.50.300 168 727 1.7E-5 T 28-03-2018 CNX65_RS31610 b4a42d797b59cc1b594b3f58c660b3e3 860 Pfam PF02575 YbaB/EbfC DNA-binding family 11 85 1.6E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS31610 b4a42d797b59cc1b594b3f58c660b3e3 860 SUPERFAMILY SSF82607 16 85 9.55E-5 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS08865 5a6c0b121efd3e24b94a107cfe2312ab 250 SUPERFAMILY SSF53790 2 231 1.7E-63 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08865 5a6c0b121efd3e24b94a107cfe2312ab 250 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS08865 5a6c0b121efd3e24b94a107cfe2312ab 250 Gene3D G3DSA:3.40.1010.10 1 121 3.3E-30 T 28-03-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08865 5a6c0b121efd3e24b94a107cfe2312ab 250 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 208 3.9E-42 T 28-03-2018 IPR000878 Tetrapyrrole methylase GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08865 5a6c0b121efd3e24b94a107cfe2312ab 250 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 242 1.8E-87 T 28-03-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 CNX65_RS08865 5a6c0b121efd3e24b94a107cfe2312ab 250 Gene3D G3DSA:3.30.950.10 122 235 5.8E-25 T 28-03-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008152|GO:0008168 Reactome: R-HSA-5358493 CNX65_RS08865 5a6c0b121efd3e24b94a107cfe2312ab 250 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 28-03-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00270+2.1.1.10|KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-5441|MetaCyc: PWY-702|MetaCyc: PWY-7377 CNX65_RS25790 8a34c5ea63a8e9dda8b4669cc9fb42c8 307 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 15 297 18.737 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CNX65_RS25790 8a34c5ea63a8e9dda8b4669cc9fb42c8 307 Pfam PF01040 UbiA prenyltransferase family 31 279 6.1E-62 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CNX65_RS25790 8a34c5ea63a8e9dda8b4669cc9fb42c8 307 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 18 295 3.9E-95 T 28-03-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 CNX65_RS25790 8a34c5ea63a8e9dda8b4669cc9fb42c8 307 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 70 92 - T 28-03-2018 IPR030470 UbiA prenyltransferase conserved site CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 PRINTS PR00412 Epoxide hydrolase signature 335 357 9.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 PRINTS PR00412 Epoxide hydrolase signature 97 115 9.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 PRINTS PR00412 Epoxide hydrolase signature 175 188 9.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 PRINTS PR00412 Epoxide hydrolase signature 117 132 9.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 PRINTS PR00412 Epoxide hydrolase signature 304 320 9.3E-12 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 PIRSF PIRSF001112 4 362 4.5E-79 T 28-03-2018 IPR016292 Epoxide hydrolase GO:0033961 KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 Gene3D G3DSA:3.40.50.1820 3 362 4.9E-77 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 Pfam PF06441 Epoxide hydrolase N terminus 6 106 2.2E-26 T 28-03-2018 IPR010497 Epoxide hydrolase, N-terminal KEGG: 00980+3.3.2.9|Reactome: R-HSA-211945 CNX65_RS21495 495babeadf7ecc5c1afa8f824ea2e639 362 SUPERFAMILY SSF53474 7 360 1.17E-82 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS15545 e808e5007685cf23a494bd869f54ae0c 313 SMART SM00418 234 310 0.0037 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS15545 e808e5007685cf23a494bd869f54ae0c 313 SUPERFAMILY SSF46785 234 305 1.29E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15545 e808e5007685cf23a494bd869f54ae0c 313 Gene3D G3DSA:1.10.10.10 231 310 4.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15545 e808e5007685cf23a494bd869f54ae0c 313 Pfam PF12840 Helix-turn-helix domain 236 289 2.0E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 Gene3D G3DSA:3.40.50.2300 64 189 3.3E-28 T 28-03-2018 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 Gene3D G3DSA:1.10.260.40 12 63 6.5E-22 T 28-03-2018 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 13 31 - T 28-03-2018 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 Pfam PF13377 Periplasmic binding protein-like domain 182 342 4.7E-29 T 28-03-2018 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 22 32 3.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 12 22 3.4E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 SUPERFAMILY SSF47413 10 68 4.88E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 12 57 2.1E-17 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 SMART SM00354 10 80 8.0E-26 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 Gene3D G3DSA:3.40.50.2300 190 343 1.8E-43 T 28-03-2018 CNX65_RS27785 3c6813ce96b8aedc3b067c775bda02ce 343 SUPERFAMILY SSF53822 83 342 6.87E-57 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS34375 cba829ff9c2598110f6b532138736bc9 372 Gene3D G3DSA:2.60.40.10 35 198 7.5E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS34375 cba829ff9c2598110f6b532138736bc9 372 Pfam PF17210 SdrD B-like domain 39 112 3.7E-9 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS34375 cba829ff9c2598110f6b532138736bc9 372 SUPERFAMILY SSF117074 35 128 1.1E-13 T 28-03-2018 CNX65_RS15520 24be01052dc64536334ec1a27b6b08cd 86 SUPERFAMILY SSF51126 27 80 3.22E-9 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS15520 24be01052dc64536334ec1a27b6b08cd 86 Gene3D G3DSA:2.160.20.10 23 86 6.8E-10 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS16835 48c402a48f636f9795acf786b317fe8a 476 Pfam PF00561 alpha/beta hydrolase fold 78 444 3.5E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS16835 48c402a48f636f9795acf786b317fe8a 476 SUPERFAMILY SSF53474 305 325 7.66E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16835 48c402a48f636f9795acf786b317fe8a 476 SUPERFAMILY SSF53474 400 448 7.66E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16835 48c402a48f636f9795acf786b317fe8a 476 SUPERFAMILY SSF53474 60 126 7.66E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16835 48c402a48f636f9795acf786b317fe8a 476 SUPERFAMILY SSF53474 168 227 7.66E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16835 48c402a48f636f9795acf786b317fe8a 476 Gene3D G3DSA:3.40.50.1820 48 464 3.5E-38 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 223 2.9E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 SUPERFAMILY SSF52172 1 125 2.13E-44 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 Gene3D G3DSA:1.10.10.10 123 227 1.3E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 SMART SM00448 1 112 6.0E-47 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 SUPERFAMILY SSF46894 125 224 6.24E-29 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 SMART SM00862 148 223 2.9E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 Pfam PF00072 Response regulator receiver domain 3 112 5.8E-32 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS03040 0aea2f59b553167ceed4c54ffb912c17 228 Gene3D G3DSA:3.40.50.2300 1 122 3.6E-42 T 28-03-2018 CNX65_RS15470 3f1c269ebd844f70bd5c9d38958faa08 110 Gene3D G3DSA:3.10.180.10 2 110 1.2E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS15470 3f1c269ebd844f70bd5c9d38958faa08 110 SUPERFAMILY SSF54593 9 108 3.26E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 Gene3D G3DSA:3.40.47.10 8 263 1.1E-73 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 374 470 6.0E-16 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 Gene3D G3DSA:3.40.47.10 267 422 1.3E-51 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 Pfam PF00698 Acyl transferase domain 500 655 1.1E-34 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 SUPERFAMILY SSF53901 11 363 5.29E-75 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 Gene3D G3DSA:3.40.366.10 485 656 2.7E-46 T 28-03-2018 CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 259 371 3.1E-35 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 501 656 4.6E-15 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 14 251 9.3E-72 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 SMART SM00825 Beta-ketoacyl synthase 16 424 8.6E-166 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 SUPERFAMILY SSF55048 618 655 4.32E-6 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS19475 555ff68b63573c573f1b13d5126038f4 656 SUPERFAMILY SSF52151 499 619 4.45E-38 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS13445 8fe62e7be85b88316836393a16d4bcd6 284 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 3 126 1.5E-8 T 28-03-2018 IPR013116 Acetohydroxy acid isomeroreductase, NADPH-binding domain KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 CNX65_RS13445 8fe62e7be85b88316836393a16d4bcd6 284 SUPERFAMILY SSF51735 5 166 6.04E-15 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13445 8fe62e7be85b88316836393a16d4bcd6 284 Gene3D G3DSA:3.40.50.720 1 176 6.7E-25 T 28-03-2018 CNX65_RS13445 8fe62e7be85b88316836393a16d4bcd6 284 Pfam PF16896 Phosphogluconate dehydrogenase (decarboxylating) C-term 124 277 9.7E-63 T 28-03-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal CNX65_RS13445 8fe62e7be85b88316836393a16d4bcd6 284 Gene3D G3DSA:1.10.3640.10 177 276 4.0E-40 T 28-03-2018 IPR031663 Phosphogluconate dehydrogenase (decarboxylating) , C-terminal CNX65_RS03815 1afd5afd04b1458e336b5d07d97e92a3 356 SUPERFAMILY SSF55031 168 269 1.64E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS03815 1afd5afd04b1458e336b5d07d97e92a3 356 Pfam PF01546 Peptidase family M20/M25/M40 68 353 6.1E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS03815 1afd5afd04b1458e336b5d07d97e92a3 356 SUPERFAMILY SSF53187 11 180 2.37E-42 T 28-03-2018 CNX65_RS03815 1afd5afd04b1458e336b5d07d97e92a3 356 SUPERFAMILY SSF53187 278 353 2.37E-42 T 28-03-2018 CNX65_RS03815 1afd5afd04b1458e336b5d07d97e92a3 356 Pfam PF07687 Peptidase dimerisation domain 168 265 8.6E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS03815 1afd5afd04b1458e336b5d07d97e92a3 356 Gene3D G3DSA:3.40.630.10 2 270 4.4E-48 T 28-03-2018 CNX65_RS03815 1afd5afd04b1458e336b5d07d97e92a3 356 TIGRFAM TIGR01900 dapE-gram_pos: succinyl-diaminopimelate desuccinylase 8 353 6.4E-154 T 28-03-2018 IPR010174 Succinyl-diaminopimelate desuccinylase, DapE GO:0009014|GO:0009089 KEGG: 00300+3.5.1.18 CNX65_RS17980 d8c21b3087261823b26e9c78af5e2556 162 Pfam PF13673 Acetyltransferase (GNAT) domain 55 146 4.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS17980 d8c21b3087261823b26e9c78af5e2556 162 SUPERFAMILY SSF55729 4 146 6.58E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS17980 d8c21b3087261823b26e9c78af5e2556 162 Gene3D G3DSA:3.40.630.30 3 159 1.9E-25 T 28-03-2018 CNX65_RS30745 c32c231c2fd9774f24b58507306c86b5 455 Gene3D G3DSA:3.30.1330.90 11 158 3.2E-55 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CNX65_RS30745 c32c231c2fd9774f24b58507306c86b5 455 SUPERFAMILY SSF143548 17 156 1.52E-42 T 28-03-2018 IPR029009 Allosteric substrate binding domain Reactome: R-HSA-977347 CNX65_RS30745 c32c231c2fd9774f24b58507306c86b5 455 Pfam PF03313 Serine dehydratase alpha chain 186 449 2.6E-105 T 28-03-2018 IPR005130 Serine dehydratase-like, alpha subunit CNX65_RS30745 c32c231c2fd9774f24b58507306c86b5 455 TIGRFAM TIGR00720 sda_mono: L-serine ammonia-lyase 3 452 3.3E-210 T 28-03-2018 IPR004644 Iron-sulphur-dependent L-serine dehydratase single chain form GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CNX65_RS30745 c32c231c2fd9774f24b58507306c86b5 455 Pfam PF03315 Serine dehydratase beta chain 4 155 1.3E-57 T 28-03-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 CNX65_RS30745 c32c231c2fd9774f24b58507306c86b5 455 Gene3D G3DSA:1.10.4100.10 243 442 9.1E-35 T 28-03-2018 CNX65_RS03460 90d628307715b7ec86d2918d62f71804 228 Gene3D G3DSA:2.40.260.10 84 228 1.1E-14 T 28-03-2018 IPR023365 Sortase domain CNX65_RS03460 90d628307715b7ec86d2918d62f71804 228 SUPERFAMILY SSF63817 104 223 1.11E-9 T 28-03-2018 IPR023365 Sortase domain CNX65_RS03460 90d628307715b7ec86d2918d62f71804 228 Pfam PF04203 Sortase family 129 225 5.2E-10 T 28-03-2018 IPR005754 Sortase family CNX65_RS24785 792af088b2eb406d0fb836c6cb3f231c 408 Pfam PF00535 Glycosyl transferase family 2 10 145 3.1E-8 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS24785 792af088b2eb406d0fb836c6cb3f231c 408 SUPERFAMILY SSF53448 10 355 3.56E-34 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS24785 792af088b2eb406d0fb836c6cb3f231c 408 Gene3D G3DSA:3.90.550.10 3 248 5.1E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS29655 1436ec40b6cb6fa1cceb5020c40ff73a 385 SUPERFAMILY SSF63829 80 321 7.19E-13 T 28-03-2018 CNX65_RS29655 1436ec40b6cb6fa1cceb5020c40ff73a 385 Gene3D G3DSA:2.120.10.30 54 367 1.8E-23 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS29655 1436ec40b6cb6fa1cceb5020c40ff73a 385 Pfam PF07995 Glucose / Sorbosone dehydrogenase 97 286 1.5E-24 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 Gene3D G3DSA:1.25.40.10 652 799 9.1E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 SMART SM00220 390 638 2.7E-23 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 SUPERFAMILY SSF48452 759 847 5.18E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 Gene3D G3DSA:1.25.40.10 800 878 0.18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 Pfam PF16919 Protein kinase G rubredoxin domain 270 389 2.1E-36 T 28-03-2018 IPR031634 Protein kinase G, rubredoxin domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 SUPERFAMILY SSF56112 375 645 2.43E-44 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 Gene3D G3DSA:3.30.200.20 375 478 2.5E-13 T 28-03-2018 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 Pfam PF00069 Protein kinase domain 391 589 4.2E-27 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 Pfam PF16918 Protein kinase G tetratricopeptide repeat 673 969 6.1E-68 T 28-03-2018 IPR031636 Protein kinase G, tetratricopeptide repeat containing domain KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1 CNX65_RS17785 2362f3646519480063b6c963d57c88bd 971 Gene3D G3DSA:1.10.510.10 479 644 2.8E-27 T 28-03-2018 CNX65_RS28785 14327f516bae06ee659c4b5c3e898720 204 PIRSF PIRSF006324 2 204 1.7E-50 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CNX65_RS28785 14327f516bae06ee659c4b5c3e898720 204 Pfam PF01810 LysE type translocator 17 203 1.3E-29 T 28-03-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 CNX65_RS19930 79aca13aaf65c23ca99d851f67327160 194 PRINTS PR00598 Bacterial regulatory protein MarR family signature 104 119 2.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS19930 79aca13aaf65c23ca99d851f67327160 194 PRINTS PR00598 Bacterial regulatory protein MarR family signature 87 103 2.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS19930 79aca13aaf65c23ca99d851f67327160 194 PRINTS PR00598 Bacterial regulatory protein MarR family signature 123 139 2.8E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS19930 79aca13aaf65c23ca99d851f67327160 194 Pfam PF12802 MarR family 67 126 1.6E-11 T 28-03-2018 CNX65_RS19930 79aca13aaf65c23ca99d851f67327160 194 Gene3D G3DSA:1.10.10.10 13 182 1.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19930 79aca13aaf65c23ca99d851f67327160 194 SUPERFAMILY SSF46785 34 178 1.7E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19930 79aca13aaf65c23ca99d851f67327160 194 SMART SM00347 60 164 1.0E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS33185 9d67992e2ea47c850d79980a10398b1c 78 SUPERFAMILY SSF52833 3 77 4.16E-19 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS33185 9d67992e2ea47c850d79980a10398b1c 78 Pfam PF05768 Glutaredoxin-like domain (DUF836) 5 77 2.2E-16 T 28-03-2018 IPR008554 Glutaredoxin-like CNX65_RS33185 9d67992e2ea47c850d79980a10398b1c 78 Gene3D G3DSA:3.40.30.10 2 78 7.0E-14 T 28-03-2018 CNX65_RS27890 7076b51845cece388705547266c59364 453 Gene3D G3DSA:1.25.10.10 13 157 0.018 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS27890 7076b51845cece388705547266c59364 453 Gene3D G3DSA:1.25.10.10 158 380 1.8E-10 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS27105 4f38b3b878827ec8f48d64d1aaf7250c 870 SUPERFAMILY SSF48452 718 867 1.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS27105 4f38b3b878827ec8f48d64d1aaf7250c 870 Gene3D G3DSA:1.25.40.10 567 870 4.0E-14 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 Pfam PF00067 Cytochrome P450 284 377 2.6E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 351 360 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 SUPERFAMILY SSF48264 25 409 4.85E-74 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 PRINTS PR00359 B-class P450 signature 160 175 2.7E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 PRINTS PR00359 B-class P450 signature 98 109 2.7E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 PRINTS PR00359 B-class P450 signature 283 294 2.7E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 PRINTS PR00359 B-class P450 signature 358 369 2.7E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 PRINTS PR00359 B-class P450 signature 349 358 2.7E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 PRINTS PR00359 B-class P450 signature 328 343 2.7E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 PRINTS PR00359 B-class P450 signature 300 327 2.7E-35 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS22370 10fecd07ee71ce7e33e1df56b0e3ec5e 427 Gene3D G3DSA:1.10.630.10 3 424 7.5E-64 T 28-03-2018 CNX65_RS25505 0afa8281f0765bbf2572c773507e802b 269 Gene3D G3DSA:3.90.226.10 14 266 6.2E-55 T 28-03-2018 CNX65_RS25505 0afa8281f0765bbf2572c773507e802b 269 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 123 143 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CNX65_RS25505 0afa8281f0765bbf2572c773507e802b 269 SUPERFAMILY SSF52096 17 260 1.93E-58 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS25505 0afa8281f0765bbf2572c773507e802b 269 Pfam PF00378 Enoyl-CoA hydratase/isomerase 26 254 1.7E-39 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS25975 5486516a589048e147599410bffbc843 221 Pfam PF00834 Ribulose-phosphate 3 epimerase family 7 201 6.8E-77 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CNX65_RS25975 5486516a589048e147599410bffbc843 221 PIRSF PIRSF001461 1 220 3.2E-91 T 28-03-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CNX65_RS25975 5486516a589048e147599410bffbc843 221 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 32 46 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CNX65_RS25975 5486516a589048e147599410bffbc843 221 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 6 214 3.5E-82 T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CNX65_RS25975 5486516a589048e147599410bffbc843 221 SUPERFAMILY SSF51366 5 215 1.93E-66 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS25975 5486516a589048e147599410bffbc843 221 ProSitePatterns PS01086 Ribulose-phosphate 3-epimerase family signature 2. 134 156 - T 28-03-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 CNX65_RS25975 5486516a589048e147599410bffbc843 221 Gene3D G3DSA:3.20.20.70 1 216 4.7E-85 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS34220 769c7c21320281adee26a99ae360d0f1 249 Pfam PF09335 SNARE associated Golgi protein 52 179 1.3E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Gene3D G3DSA:3.40.50.980 84 198 2.2E-10 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Pfam PF00501 AMP-binding enzyme 205 354 3.4E-28 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Pfam PF00501 AMP-binding enzyme 363 530 1.5E-10 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 SUPERFAMILY SSF56801 27 202 2.09E-17 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 SUPERFAMILY SSF56801 201 574 5.63E-75 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 ProSitePatterns PS00455 Putative AMP-binding domain signature. 327 338 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Gene3D G3DSA:3.40.50.980 199 332 2.4E-32 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Gene3D G3DSA:2.30.38.10 446 523 1.2E-7 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Gene3D G3DSA:3.40.50.980 359 445 7.4E-9 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Gene3D G3DSA:3.40.50.980 333 358 9.7E-9 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Gene3D G3DSA:3.40.50.980 24 68 0.25 T 28-03-2018 CNX65_RS14640 323abd37498be649e7b56ba83ffbf289 809 Gene3D G3DSA:3.30.300.30 524 786 1.8E-13 T 28-03-2018 CNX65_RS05040 029239ab78fe9d2fae75cb5b948e242c 99 SUPERFAMILY SSF54736 22 97 1.83E-24 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CNX65_RS05040 029239ab78fe9d2fae75cb5b948e242c 99 Gene3D G3DSA:3.30.1390.10 24 95 7.5E-27 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CNX65_RS05040 029239ab78fe9d2fae75cb5b948e242c 99 Pfam PF02617 ATP-dependent Clp protease adaptor protein ClpS 23 93 4.1E-23 T 28-03-2018 IPR003769 Adaptor protein ClpS, core GO:0030163 Reactome: R-HSA-983168 CNX65_RS05040 029239ab78fe9d2fae75cb5b948e242c 99 Hamap MF_00302 ATP-dependent Clp protease adapter protein ClpS [clpS]. 2 99 17.442 T 28-03-2018 IPR022935 ATP-dependent Clp protease adaptor protein ClpS CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 SUPERFAMILY SSF48498 79 180 6.43E-6 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 Gene3D G3DSA:1.10.10.60 2 53 2.4E-13 T 28-03-2018 CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 SUPERFAMILY SSF46689 4 73 2.15E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 53 1.3E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 81 173 2.4E-7 T 28-03-2018 CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13565 63a88debff549671f98648c9b99a4212 210 Gene3D G3DSA:1.10.357.10 54 200 1.7E-13 T 28-03-2018 CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 SUPERFAMILY SSF51735 146 321 1.13E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 16 146 2.9E-39 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 SMART SM01003 16 146 1.2E-56 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 Gene3D G3DSA:3.40.50.720 12 213 1.4E-39 T 28-03-2018 CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 150 365 2.1E-63 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 Gene3D G3DSA:3.40.50.720 214 369 4.6E-36 T 28-03-2018 CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 SMART SM01002 155 317 7.9E-73 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CNX65_RS23605 98466c47f91e2532949d9460ee630041 369 SUPERFAMILY SSF52283 14 176 1.19E-45 T 28-03-2018 CNX65_RS34645 bb9877a7a27b4ada944bfef662a11031 190 Gene3D G3DSA:1.10.357.10 63 187 1.3E-18 T 28-03-2018 CNX65_RS34645 bb9877a7a27b4ada944bfef662a11031 190 Gene3D G3DSA:1.10.260.40 35 62 7.5E-9 T 28-03-2018 CNX65_RS34645 bb9877a7a27b4ada944bfef662a11031 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 12 57 8.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34645 bb9877a7a27b4ada944bfef662a11031 190 SUPERFAMILY SSF48498 77 189 1.11E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS34645 bb9877a7a27b4ada944bfef662a11031 190 Pfam PF13977 BetI-type transcriptional repressor, C-terminal 78 187 5.7E-9 T 28-03-2018 CNX65_RS34645 bb9877a7a27b4ada944bfef662a11031 190 SUPERFAMILY SSF46689 3 79 2.14E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS34645 bb9877a7a27b4ada944bfef662a11031 190 Gene3D G3DSA:1.10.10.60 1 34 1.5E-6 T 28-03-2018 CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 SUPERFAMILY SSF51735 12 239 9.61E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 2.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 84 95 2.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 183 2.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 Gene3D G3DSA:3.40.50.720 1 292 2.8E-61 T 28-03-2018 CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 187 204 4.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 183 4.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 84 95 4.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 4.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 4.7E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS28760 92d2687c6a58e64a564959110685441c 297 Pfam PF00106 short chain dehydrogenase 16 206 2.0E-23 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS16185 472ac7d37776d7e287bc64c389c3ec5b 294 Gene3D G3DSA:3.40.50.150 17 278 6.0E-47 T 28-03-2018 CNX65_RS16185 472ac7d37776d7e287bc64c389c3ec5b 294 Pfam PF04072 Leucine carboxyl methyltransferase 23 197 2.6E-49 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CNX65_RS16185 472ac7d37776d7e287bc64c389c3ec5b 294 SUPERFAMILY SSF53335 19 277 5.48E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS16185 472ac7d37776d7e287bc64c389c3ec5b 294 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 20 271 2.3E-82 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CNX65_RS14730 0a7c1504c363937015b8d870e5726536 326 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 197 219 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CNX65_RS14730 0a7c1504c363937015b8d870e5726536 326 SUPERFAMILY SSF52283 20 134 4.25E-10 T 28-03-2018 CNX65_RS14730 0a7c1504c363937015b8d870e5726536 326 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 126 286 3.2E-42 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CNX65_RS14730 0a7c1504c363937015b8d870e5726536 326 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 24 317 4.3E-7 T 28-03-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0008152|GO:0016616|GO:0051287|GO:0055114 CNX65_RS14730 0a7c1504c363937015b8d870e5726536 326 SUPERFAMILY SSF51735 100 287 2.28E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS14730 0a7c1504c363937015b8d870e5726536 326 Gene3D G3DSA:3.40.50.720 8 108 5.4E-13 T 28-03-2018 CNX65_RS14730 0a7c1504c363937015b8d870e5726536 326 Gene3D G3DSA:3.40.50.720 109 288 2.3E-44 T 28-03-2018 CNX65_RS20030 3c3d2263b178665663c6d65568f56043 155 Gene3D G3DSA:3.30.370.10 39 134 7.1E-4 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CNX65_RS23040 21c07410d04df9e8d6abbafd0f1d1622 412 SUPERFAMILY SSF103473 11 394 1.09E-31 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23040 21c07410d04df9e8d6abbafd0f1d1622 412 Gene3D G3DSA:1.20.1250.20 5 202 2.0E-15 T 28-03-2018 CNX65_RS23040 21c07410d04df9e8d6abbafd0f1d1622 412 Gene3D G3DSA:1.20.1250.20 203 406 5.6E-16 T 28-03-2018 CNX65_RS21115 03339376a833bb60c504555083229483 271 Pfam PF13460 NAD(P)H-binding 36 180 1.1E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21115 03339376a833bb60c504555083229483 271 Gene3D G3DSA:3.40.50.720 27 187 8.8E-15 T 28-03-2018 CNX65_RS21115 03339376a833bb60c504555083229483 271 SUPERFAMILY SSF51735 227 266 2.64E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21115 03339376a833bb60c504555083229483 271 SUPERFAMILY SSF51735 31 181 2.64E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS27950 74a0545d9346dd4eb1ce21fc6ab8e756 269 Gene3D G3DSA:3.20.20.70 11 260 3.3E-66 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS27950 74a0545d9346dd4eb1ce21fc6ab8e756 269 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 51 68 - T 28-03-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 CNX65_RS27950 74a0545d9346dd4eb1ce21fc6ab8e756 269 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 2 257 32.594 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CNX65_RS27950 74a0545d9346dd4eb1ce21fc6ab8e756 269 SUPERFAMILY SSF51366 12 257 6.88E-77 T 28-03-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824|GO:0008152 CNX65_RS27950 74a0545d9346dd4eb1ce21fc6ab8e756 269 Pfam PF00218 Indole-3-glycerol phosphate synthase 4 255 1.3E-76 T 28-03-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 SUPERFAMILY SSF52540 2 194 3.81E-35 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 192 23.973 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 Gene3D G3DSA:3.30.460.10 206 388 1.2E-49 T 28-03-2018 CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 Gene3D G3DSA:3.40.50.300 1 194 2.0E-41 T 28-03-2018 CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 4 181 4.8E-39 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 Pfam PF04229 GrpB protein 211 380 2.4E-43 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 Pfam PF01121 Dephospho-CoA kinase 4 178 2.5E-54 T 28-03-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 CNX65_RS27490 a2488615e6e4af7df3d4aae1fb691fb9 394 SUPERFAMILY SSF81301 213 385 6.54E-40 T 28-03-2018 CNX65_RS09170 f107f16ae509a0988938b38f84a76c87 115 Gene3D G3DSA:1.10.287.850 1 57 0.4 T 28-03-2018 CNX65_RS09170 f107f16ae509a0988938b38f84a76c87 115 Gene3D G3DSA:1.10.287.1060 58 113 6.9E-5 T 28-03-2018 CNX65_RS31765 aa243005f2077169e0770125a065ac14 102 Gene3D G3DSA:3.30.460.10 1 98 7.9E-14 T 28-03-2018 CNX65_RS31765 aa243005f2077169e0770125a065ac14 102 SUPERFAMILY SSF81301 8 100 1.06E-10 T 28-03-2018 CNX65_RS31765 aa243005f2077169e0770125a065ac14 102 Pfam PF01909 Nucleotidyltransferase domain 12 96 6.9E-9 T 28-03-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 CNX65_RS13800 10787082935bfd051f534c15cd047858 340 SUPERFAMILY SSF53807 47 322 2.55E-35 T 28-03-2018 CNX65_RS13800 10787082935bfd051f534c15cd047858 340 Gene3D G3DSA:3.40.50.1980 161 340 1.0E-15 T 28-03-2018 CNX65_RS13800 10787082935bfd051f534c15cd047858 340 Pfam PF01497 Periplasmic binding protein 73 310 7.0E-18 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS13800 10787082935bfd051f534c15cd047858 340 Gene3D G3DSA:3.40.50.1980 40 156 1.9E-17 T 28-03-2018 CNX65_RS34425 158dfda8ae256b0b94f3518de77d8d18 97 Pfam PF00166 Chaperonin 10 Kd subunit 1 84 1.2E-16 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS34425 158dfda8ae256b0b94f3518de77d8d18 97 SMART SM00883 1 85 1.1E-20 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS34425 158dfda8ae256b0b94f3518de77d8d18 97 SUPERFAMILY SSF50129 2 84 7.97E-18 T 28-03-2018 IPR011032 GroES-like CNX65_RS34425 158dfda8ae256b0b94f3518de77d8d18 97 Gene3D G3DSA:2.30.33.40 1 86 1.3E-19 T 28-03-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 CNX65_RS04325 ae7712206e3c722a830a1fa3008c8fcb 218 Gene3D G3DSA:3.40.1800.10 157 216 2.1E-16 T 28-03-2018 CNX65_RS04325 ae7712206e3c722a830a1fa3008c8fcb 218 SMART SM00507 165 215 1.9E-8 T 28-03-2018 IPR003615 HNH nuclease CNX65_RS04325 ae7712206e3c722a830a1fa3008c8fcb 218 Pfam PF14279 HNH endonuclease 178 213 1.2E-6 T 28-03-2018 IPR029471 HNH endonuclease 5 CNX65_RS23935 8fab6c69ebe9c120d1bf624639e50ba4 239 SUPERFAMILY SSF51182 18 137 2.34E-13 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS23935 8fab6c69ebe9c120d1bf624639e50ba4 239 Pfam PF07883 Cupin domain 26 87 7.7E-8 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CNX65_RS23935 8fab6c69ebe9c120d1bf624639e50ba4 239 Gene3D G3DSA:2.60.120.10 4 175 7.2E-26 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS05105 24aa0f50ef2655ea19adc942b5929fb2 135 SUPERFAMILY SSF82784 7 130 1.44E-16 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS05105 24aa0f50ef2655ea19adc942b5929fb2 135 Pfam PF02566 OsmC-like protein 33 127 2.1E-11 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS05105 24aa0f50ef2655ea19adc942b5929fb2 135 Gene3D G3DSA:3.30.300.20 4 134 9.2E-15 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS16695 533899e3c07ba2f16a83a805ddae2f7d 132 Pfam PF13471 Transglutaminase-like superfamily 17 129 1.4E-27 T 28-03-2018 IPR032708 Microcin J25-processing protein McjB, C-terminal CNX65_RS31830 07d4531e5b75bf534a073f768d4b07cd 317 SMART SM00382 39 224 3.1E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS31830 07d4531e5b75bf534a073f768d4b07cd 317 Pfam PF00005 ABC transporter 32 174 1.7E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS31830 07d4531e5b75bf534a073f768d4b07cd 317 SUPERFAMILY SSF52540 27 239 3.31E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31830 07d4531e5b75bf534a073f768d4b07cd 317 Gene3D G3DSA:3.40.50.300 1 295 1.6E-52 T 28-03-2018 CNX65_RS02660 6ec7592284e662c977c8c3fac1297c5e 397 Gene3D G3DSA:3.20.20.140 70 323 6.1E-27 T 28-03-2018 CNX65_RS02660 6ec7592284e662c977c8c3fac1297c5e 397 SUPERFAMILY SSF51556 55 345 9.28E-49 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS02660 6ec7592284e662c977c8c3fac1297c5e 397 Gene3D G3DSA:2.30.40.10 2 69 5.6E-17 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02660 6ec7592284e662c977c8c3fac1297c5e 397 Gene3D G3DSA:2.30.40.10 324 385 6.8E-11 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02660 6ec7592284e662c977c8c3fac1297c5e 397 SUPERFAMILY SSF51338 345 381 2.78E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02660 6ec7592284e662c977c8c3fac1297c5e 397 SUPERFAMILY SSF51338 3 56 2.78E-20 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS02660 6ec7592284e662c977c8c3fac1297c5e 397 Pfam PF07969 Amidohydrolase family 182 380 6.1E-14 T 28-03-2018 IPR013108 Amidohydrolase 3 CNX65_RS04940 2f7b0ead32669666817380f448d89328 224 TIGRFAM TIGR01691 enolase-ppase: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 5 221 7.6E-62 T 28-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 CNX65_RS04940 2f7b0ead32669666817380f448d89328 224 Gene3D G3DSA:3.40.50.1000 81 224 4.4E-16 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS04940 2f7b0ead32669666817380f448d89328 224 Hamap MF_01681 Enolase-phosphatase E1 [mtnC]. 1 220 36.845 T 28-03-2018 IPR023943 Enolase-phosphatase E1 GO:0000287|GO:0019509|GO:0043874 KEGG: 00270+3.1.3.77|Reactome: R-HSA-1237112 CNX65_RS04940 2f7b0ead32669666817380f448d89328 224 SUPERFAMILY SSF56784 1 222 7.42E-52 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 410 7.7E-114 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 Gene3D G3DSA:3.65.10.10 24 225 5.1E-58 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 ProSitePatterns PS00885 EPSP synthase signature 2. 332 350 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 ProSitePatterns PS00104 EPSP synthase signature 1. 87 101 - T 28-03-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 18 417 8.8E-118 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 Gene3D G3DSA:3.65.10.10 226 418 1.8E-50 T 28-03-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 SUPERFAMILY SSF55205 9 415 9.81E-111 T 28-03-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 PIRSF PIRSF000505 2 420 2.0E-117 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CNX65_RS31015 507ad455e257f3480cc99a8bcd2c53ed 420 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 12 419 29.654 T 28-03-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 CNX65_RS08885 40a5f88d372593d9abc6c25eaf683347 345 Gene3D G3DSA:3.30.413.10 277 343 2.0E-7 T 28-03-2018 CNX65_RS08885 40a5f88d372593d9abc6c25eaf683347 345 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 26 71 3.3E-7 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS08885 40a5f88d372593d9abc6c25eaf683347 345 SUPERFAMILY SSF55124 4 87 6.38E-15 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS08885 40a5f88d372593d9abc6c25eaf683347 345 SUPERFAMILY SSF55124 164 264 9.16E-7 T 28-03-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 CNX65_RS08885 40a5f88d372593d9abc6c25eaf683347 345 Gene3D G3DSA:3.90.480.10 25 270 1.8E-26 T 28-03-2018 CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 SUPERFAMILY SSF46785 30 96 1.41E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 Gene3D G3DSA:2.10.109.10 119 235 8.7E-25 T 28-03-2018 CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 TIGRFAM TIGR00498 lexA: repressor LexA 30 234 8.7E-75 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 189 201 1.0E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 150 160 1.0E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 161 172 1.0E-10 T 28-03-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 Hamap MF_00015 LexA repressor [lexA]. 30 235 33.554 T 28-03-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 SUPERFAMILY SSF51306 114 233 1.69E-33 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 Pfam PF00717 Peptidase S24-like 153 219 1.5E-13 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 Gene3D G3DSA:1.10.10.10 29 95 5.7E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07105 7513de2cd3b79954e940c389deabdaf5 235 Pfam PF01726 LexA DNA binding domain 30 92 1.6E-27 T 28-03-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 79 180 5.1E-14 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 Gene3D G3DSA:3.40.50.1000 64 193 1.0E-27 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 Pfam PF13419 Haloacid dehalogenase-like hydrolase 4 181 1.9E-21 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 Gene3D G3DSA:3.40.50.1000 1 27 0.0027 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 144 164 1.6E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 12 1.6E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 126 142 1.6E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 171 184 1.6E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 SUPERFAMILY SSF56784 1 210 2.8E-47 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34730 f2344028ca36386ebd1e704d8c67d828 213 Gene3D G3DSA:1.10.150.240 28 63 2.7E-17 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CNX65_RS16715 48388a11a1d3dbb13c7cdfabff935807 227 Gene3D G3DSA:1.10.357.10 10 223 9.3E-25 T 28-03-2018 CNX65_RS16715 48388a11a1d3dbb13c7cdfabff935807 227 SUPERFAMILY SSF46689 9 81 3.49E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16715 48388a11a1d3dbb13c7cdfabff935807 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 65 1.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS02605 b78c0f41ead7bde0ed195ccb9db23983 274 SUPERFAMILY SSF55874 155 264 2.01E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02605 b78c0f41ead7bde0ed195ccb9db23983 274 Gene3D G3DSA:3.30.565.10 84 271 8.9E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS02605 b78c0f41ead7bde0ed195ccb9db23983 274 Pfam PF07730 Histidine kinase 92 155 1.4E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS01120 26bc4dba0068d2835d83dd5e973f756e 374 SUPERFAMILY SSF52540 12 185 1.86E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01120 26bc4dba0068d2835d83dd5e973f756e 374 SUPERFAMILY SSF52540 227 293 1.86E-33 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01120 26bc4dba0068d2835d83dd5e973f756e 374 Gene3D G3DSA:3.40.50.300 2 374 4.4E-99 T 28-03-2018 CNX65_RS01120 26bc4dba0068d2835d83dd5e973f756e 374 Pfam PF02374 Anion-transporting ATPase 16 285 4.7E-24 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CNX65_RS20635 5a0e582afce48fd6eec825f03e76d870 608 SUPERFAMILY SSF51905 7 260 3.31E-20 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20635 5a0e582afce48fd6eec825f03e76d870 608 Gene3D G3DSA:3.50.50.60 201 423 1.8E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20635 5a0e582afce48fd6eec825f03e76d870 608 Pfam PF13454 FAD-NAD(P)-binding 12 179 6.4E-30 T 28-03-2018 CNX65_RS20635 5a0e582afce48fd6eec825f03e76d870 608 Gene3D G3DSA:3.50.50.60 6 200 1.1E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20635 5a0e582afce48fd6eec825f03e76d870 608 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 218 236 3.7E-8 T 28-03-2018 CNX65_RS20635 5a0e582afce48fd6eec825f03e76d870 608 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 3.7E-8 T 28-03-2018 CNX65_RS20635 5a0e582afce48fd6eec825f03e76d870 608 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 3.7E-8 T 28-03-2018 CNX65_RS26420 1cd26fd7c8b83a08aa2f1a189e3bbb42 264 Gene3D G3DSA:1.10.3720.10 1 254 2.1E-34 T 28-03-2018 CNX65_RS26420 1cd26fd7c8b83a08aa2f1a189e3bbb42 264 SUPERFAMILY SSF161098 2 264 1.12E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS26420 1cd26fd7c8b83a08aa2f1a189e3bbb42 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 250 5.3E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 1.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 1.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 1.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 1.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 1.8E-43 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 28-03-2018 IPR033135 ClpP, histidine active site CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 Pfam PF00574 Clp protease 27 201 2.5E-77 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 39.908 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 SUPERFAMILY SSF52096 20 204 2.4E-63 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 28-03-2018 IPR018215 ClpP, Ser active site CNX65_RS05520 5c586bcf3a9e058b664223adb443e3ec 209 Gene3D G3DSA:3.90.226.10 11 204 1.0E-39 T 28-03-2018 CNX65_RS04260 74fed4e0d5325027016aeed2f2aa11f3 428 Pfam PF00675 Insulinase (Peptidase family M16) 16 131 1.0E-18 T 28-03-2018 IPR011765 Peptidase M16, N-terminal CNX65_RS04260 74fed4e0d5325027016aeed2f2aa11f3 428 SUPERFAMILY SSF63411 231 420 4.83E-25 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CNX65_RS04260 74fed4e0d5325027016aeed2f2aa11f3 428 Gene3D G3DSA:3.30.830.10 3 226 4.9E-56 T 28-03-2018 CNX65_RS04260 74fed4e0d5325027016aeed2f2aa11f3 428 Gene3D G3DSA:3.30.830.10 233 425 3.2E-28 T 28-03-2018 CNX65_RS04260 74fed4e0d5325027016aeed2f2aa11f3 428 SUPERFAMILY SSF63411 3 221 1.78E-51 T 28-03-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 CNX65_RS04260 74fed4e0d5325027016aeed2f2aa11f3 428 Pfam PF05193 Peptidase M16 inactive domain 172 352 5.2E-26 T 28-03-2018 IPR007863 Peptidase M16, C-terminal CNX65_RS31025 e017210de0b10964e85a7ab7e00b40cd 125 SUPERFAMILY SSF54593 2 122 3.09E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS31025 e017210de0b10964e85a7ab7e00b40cd 125 Gene3D G3DSA:3.10.180.10 1 124 7.3E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS31025 e017210de0b10964e85a7ab7e00b40cd 125 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 3 118 4.3E-9 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS00665 07c830a14436e3cef703a0176d0fb14a 298 Gene3D G3DSA:3.90.550.10 3 254 3.6E-18 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS00665 07c830a14436e3cef703a0176d0fb14a 298 Pfam PF00535 Glycosyl transferase family 2 12 137 3.7E-10 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS00665 07c830a14436e3cef703a0176d0fb14a 298 SUPERFAMILY SSF53448 12 290 1.53E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 PIRSF PIRSF039144 1 112 3.7E-53 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 28-03-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 SMART SM00938 4 105 6.6E-61 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 SUPERFAMILY SSF54913 2 112 3.5E-43 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 PRINTS PR00340 P-II protein signature 83 103 4.4E-39 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 PRINTS PR00340 P-II protein signature 2 17 4.4E-39 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 PRINTS PR00340 P-II protein signature 23 41 4.4E-39 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 PRINTS PR00340 P-II protein signature 52 75 4.4E-39 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 Gene3D G3DSA:3.30.70.120 1 109 2.0E-46 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 ProSitePatterns PS00496 P-II protein uridylation site. 46 51 - T 28-03-2018 IPR002332 Nitrogen regulatory protein P-II, urydylation site GO:0006808|GO:0030234 CNX65_RS29125 f7ab231a58b1f20dd087dca34ef2e17d 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 6.6E-42 T 28-03-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 CNX65_RS17945 99ba352622991019c9acc4899404b946 382 Gene3D G3DSA:3.40.50.720 7 146 3.2E-13 T 28-03-2018 CNX65_RS17945 99ba352622991019c9acc4899404b946 382 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 12 125 3.0E-11 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CNX65_RS17945 99ba352622991019c9acc4899404b946 382 SUPERFAMILY SSF51735 13 182 2.12E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17945 99ba352622991019c9acc4899404b946 382 Gene3D G3DSA:3.30.360.10 147 336 2.2E-41 T 28-03-2018 CNX65_RS17945 99ba352622991019c9acc4899404b946 382 SUPERFAMILY SSF55347 131 330 1.77E-34 T 28-03-2018 CNX65_RS17945 99ba352622991019c9acc4899404b946 382 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 130 377 4.3E-41 T 28-03-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 CNX65_RS20315 3f7e6a0d3903eba498a9428c5aa24346 258 SUPERFAMILY SSF56281 2 252 1.76E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS20315 3f7e6a0d3903eba498a9428c5aa24346 258 Gene3D G3DSA:3.60.15.10 12 256 2.2E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS20315 3f7e6a0d3903eba498a9428c5aa24346 258 Pfam PF00753 Metallo-beta-lactamase superfamily 20 232 1.9E-17 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS20315 3f7e6a0d3903eba498a9428c5aa24346 258 SMART SM00849 19 249 2.8E-11 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS03370 77794ad9477fc6e86722c11bebbe10e0 308 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 307 2.4E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03370 77794ad9477fc6e86722c11bebbe10e0 308 SUPERFAMILY SSF161098 90 289 1.74E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03370 77794ad9477fc6e86722c11bebbe10e0 308 Gene3D G3DSA:1.10.3720.10 2 299 3.6E-41 T 28-03-2018 CNX65_RS30990 ec14de5cd9addcc82976f237e30e70f8 130 TIGRFAM TIGR03988 antisig_RsrA: mycothiol system anti-sigma-R factor 10 84 2.3E-29 T 28-03-2018 IPR024020 Anti sigma-R factor, mycothiol system,RsrA CNX65_RS30990 ec14de5cd9addcc82976f237e30e70f8 130 Pfam PF13490 Putative zinc-finger 11 44 9.9E-5 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS30990 ec14de5cd9addcc82976f237e30e70f8 130 TIGRFAM TIGR02949 anti_SigH_actin: anti-sigma factor, TIGR02949 family 4 84 1.3E-26 T 28-03-2018 IPR014295 Anti-sigma factor CNX65_RS04130 910e4bb1d8a0889479246b82dc2508d4 450 Gene3D G3DSA:1.20.1250.20 235 438 2.0E-19 T 28-03-2018 CNX65_RS04130 910e4bb1d8a0889479246b82dc2508d4 450 Pfam PF07690 Major Facilitator Superfamily 60 396 1.1E-13 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS04130 910e4bb1d8a0889479246b82dc2508d4 450 Gene3D G3DSA:1.20.1250.20 25 232 1.7E-13 T 28-03-2018 CNX65_RS04130 910e4bb1d8a0889479246b82dc2508d4 450 SUPERFAMILY SSF103473 23 435 4.05E-38 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 PRINTS PR00996 Glutamate methyltransferase family signature 106 126 5.3E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 PRINTS PR00996 Glutamate methyltransferase family signature 66 78 5.3E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 PRINTS PR00996 Glutamate methyltransferase family signature 226 249 5.3E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 PRINTS PR00996 Glutamate methyltransferase family signature 139 155 5.3E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 PRINTS PR00996 Glutamate methyltransferase family signature 27 40 5.3E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 PRINTS PR00996 Glutamate methyltransferase family signature 207 221 5.3E-38 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 Gene3D G3DSA:3.40.50.150 72 269 7.0E-44 T 28-03-2018 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 Pfam PF01739 CheR methyltransferase, SAM binding domain 73 260 8.2E-55 T 28-03-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 Pfam PF03705 CheR methyltransferase, all-alpha domain 7 57 2.6E-8 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 SUPERFAMILY SSF47757 2 72 2.35E-11 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 SMART SM00138 5 268 6.0E-84 T 28-03-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 Gene3D G3DSA:1.10.155.10 1 71 1.2E-10 T 28-03-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal CNX65_RS11800 3eb2b99f58df262d6baaebf98b4028d5 291 SUPERFAMILY SSF53335 73 260 1.72E-48 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS00930 3f57b95786d946d1dcff7dc3d0eabdd0 108 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 87 9.2E-22 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS00930 3f57b95786d946d1dcff7dc3d0eabdd0 108 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 1 93 19.718 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS00930 3f57b95786d946d1dcff7dc3d0eabdd0 108 SUPERFAMILY SSF82607 1 93 7.19E-28 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS00930 3f57b95786d946d1dcff7dc3d0eabdd0 108 PIRSF PIRSF004555 1 105 5.9E-32 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS00930 3f57b95786d946d1dcff7dc3d0eabdd0 108 Gene3D G3DSA:3.30.1310.10 1 103 1.8E-36 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS00930 3f57b95786d946d1dcff7dc3d0eabdd0 108 Pfam PF02575 YbaB/EbfC DNA-binding family 6 94 2.8E-33 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS30510 fcadd9d352d428144d25752136b06a6d 250 Gene3D G3DSA:3.40.50.720 112 246 3.0E-5 T 28-03-2018 CNX65_RS30510 fcadd9d352d428144d25752136b06a6d 250 SUPERFAMILY SSF51735 2 244 1.75E-32 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30510 fcadd9d352d428144d25752136b06a6d 250 Gene3D G3DSA:3.40.50.720 1 111 5.1E-12 T 28-03-2018 CNX65_RS21820 6f9725106d59b8c0c106e01d30b4fefa 448 Pfam PF00070 Pyridine nucleotide-disulphide oxidoreductase 7 38 1.4E-4 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21820 6f9725106d59b8c0c106e01d30b4fefa 448 SUPERFAMILY SSF51905 300 366 4.56E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21820 6f9725106d59b8c0c106e01d30b4fefa 448 SUPERFAMILY SSF51905 6 193 4.56E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21820 6f9725106d59b8c0c106e01d30b4fefa 448 Gene3D G3DSA:3.50.50.60 2 342 8.1E-24 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09445 4aa5d6e501cffff1d364c7a680e72448 382 Gene3D G3DSA:3.40.50.2000 193 351 2.0E-38 T 28-03-2018 CNX65_RS09445 4aa5d6e501cffff1d364c7a680e72448 382 Pfam PF00534 Glycosyl transferases group 1 195 342 2.9E-30 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS09445 4aa5d6e501cffff1d364c7a680e72448 382 Gene3D G3DSA:3.40.50.2000 13 192 9.2E-28 T 28-03-2018 CNX65_RS09445 4aa5d6e501cffff1d364c7a680e72448 382 SUPERFAMILY SSF53756 19 366 5.14E-78 T 28-03-2018 CNX65_RS09445 4aa5d6e501cffff1d364c7a680e72448 382 Pfam PF13439 Glycosyltransferase Family 4 22 179 2.8E-31 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS07365 e4eeebb522de51742a5388b5095d86e8 330 PIRSF PIRSF001365 1 304 3.2E-51 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS07365 e4eeebb522de51742a5388b5095d86e8 330 SUPERFAMILY SSF51569 2 290 7.33E-61 T 28-03-2018 CNX65_RS07365 e4eeebb522de51742a5388b5095d86e8 330 SMART SM01130 2 295 1.4E-66 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS07365 e4eeebb522de51742a5388b5095d86e8 330 Hamap MF_00694 Probable 5-dehydro-4-deoxyglucarate dehydratase. 2 296 43.958 T 28-03-2018 IPR017655 5-dehydro-4-deoxyglucarate dehydratase GO:0016052|GO:0047448 KEGG: 00053+4.2.1.41|MetaCyc: PWY-6486|MetaCyc: PWY-6497|MetaCyc: PWY-6499|MetaCyc: PWY-6501 CNX65_RS07365 e4eeebb522de51742a5388b5095d86e8 330 Gene3D G3DSA:3.20.20.70 1 298 1.2E-65 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS07365 e4eeebb522de51742a5388b5095d86e8 330 Pfam PF00701 Dihydrodipicolinate synthetase family 3 293 5.4E-49 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS08765 9d14c6508b8abba3ec7ec261ba6acb82 153 SUPERFAMILY SSF54637 10 147 2.03E-29 T 28-03-2018 IPR029069 HotDog domain CNX65_RS08765 9d14c6508b8abba3ec7ec261ba6acb82 153 Gene3D G3DSA:3.10.129.10 6 152 3.9E-24 T 28-03-2018 CNX65_RS08765 9d14c6508b8abba3ec7ec261ba6acb82 153 Pfam PF03061 Thioesterase superfamily 55 133 2.6E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CNX65_RS08710 2b8c8bbe112af44453f29bd960e09db7 282 Pfam PF11316 Putative rhamnosyl transferase 2 209 1.2E-42 T 28-03-2018 IPR021466 Putative rhamnosyl transferase CNX65_RS06135 86089f5a7246465ba0d3ff772759482b 242 Gene3D G3DSA:3.40.50.1400 1 108 1.9E-25 T 28-03-2018 CNX65_RS06135 86089f5a7246465ba0d3ff772759482b 242 SUPERFAMILY SSF53800 2 228 2.07E-37 T 28-03-2018 CNX65_RS06135 86089f5a7246465ba0d3ff772759482b 242 Pfam PF01903 CbiX 5 105 4.6E-20 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CNX65_RS06135 86089f5a7246465ba0d3ff772759482b 242 Pfam PF01903 CbiX 130 223 2.1E-8 T 28-03-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 CNX65_RS06135 86089f5a7246465ba0d3ff772759482b 242 Gene3D G3DSA:3.40.50.1400 109 218 1.4E-18 T 28-03-2018 CNX65_RS16875 3523e5a1c0db89732cd3bcbccd42fd6a 373 Gene3D G3DSA:1.20.1090.10 184 372 1.7E-31 T 28-03-2018 CNX65_RS16875 3523e5a1c0db89732cd3bcbccd42fd6a 373 SUPERFAMILY SSF56796 3 349 5.63E-84 T 28-03-2018 CNX65_RS16875 3523e5a1c0db89732cd3bcbccd42fd6a 373 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 28-03-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 CNX65_RS16875 3523e5a1c0db89732cd3bcbccd42fd6a 373 Pfam PF00465 Iron-containing alcohol dehydrogenase 8 348 3.0E-87 T 28-03-2018 IPR001670 Alcohol dehydrogenase, iron-type GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 CNX65_RS16875 3523e5a1c0db89732cd3bcbccd42fd6a 373 Gene3D G3DSA:3.40.50.1970 1 183 6.6E-46 T 28-03-2018 CNX65_RS27195 8bc26d19c1aaab34462504bd5cc7c6bb 79 Gene3D G3DSA:1.10.10.60 2 30 1.2E-5 T 28-03-2018 CNX65_RS27195 8bc26d19c1aaab34462504bd5cc7c6bb 79 SUPERFAMILY SSF47413 7 73 7.88E-18 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS27195 8bc26d19c1aaab34462504bd5cc7c6bb 79 Gene3D G3DSA:3.30.1190.10 31 76 2.7E-14 T 28-03-2018 CNX65_RS27195 8bc26d19c1aaab34462504bd5cc7c6bb 79 Pfam PF01381 Helix-turn-helix 17 65 1.7E-16 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS27195 8bc26d19c1aaab34462504bd5cc7c6bb 79 SMART SM00530 10 66 2.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS16180 a1159e28c6ab8966cac86b87bc74b087 259 Pfam PF00797 N-acetyltransferase 22 248 6.0E-44 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CNX65_RS16180 a1159e28c6ab8966cac86b87bc74b087 259 Gene3D G3DSA:3.30.2140.10 145 253 5.3E-5 T 28-03-2018 CNX65_RS16180 a1159e28c6ab8966cac86b87bc74b087 259 SUPERFAMILY SSF54001 2 250 4.66E-57 T 28-03-2018 CNX65_RS16180 a1159e28c6ab8966cac86b87bc74b087 259 Gene3D G3DSA:3.30.2140.10 1 144 7.5E-27 T 28-03-2018 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 SUPERFAMILY SSF50494 35 251 1.44E-47 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 Pfam PF00089 Trypsin 38 247 1.3E-36 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 Gene3D G3DSA:2.40.10.10 123 252 1.6E-22 T 28-03-2018 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 Gene3D G3DSA:2.40.10.10 37 67 2.5E-16 T 28-03-2018 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 SMART SM00020 36 247 2.1E-33 T 28-03-2018 IPR001254 Serine proteases, trypsin domain GO:0004252|GO:0006508 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 63 78 3.8E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 111 125 3.8E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 PRINTS PR00722 Chymotrypsin serine protease family (S1) signature 195 207 3.8E-12 T 28-03-2018 IPR001314 Peptidase S1A, chymotrypsin family GO:0004252|GO:0006508 CNX65_RS03600 10782eea67352d297bc091c6801a2624 254 Gene3D G3DSA:2.40.10.10 68 122 3.9E-16 T 28-03-2018 CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 Gene3D G3DSA:3.30.465.10 333 422 8.4E-21 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 SMART SM01091 341 422 3.1E-18 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 Pfam PF00571 CBS domain 280 326 2.4E-7 T 28-03-2018 IPR000644 CBS domain CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 Pfam PF00571 CBS domain 216 267 0.0047 T 28-03-2018 IPR000644 CBS domain CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 Pfam PF01595 Domain of unknown function DUF21 10 190 2.7E-46 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 Gene3D G3DSA:3.10.580.10 190 332 3.8E-31 T 28-03-2018 CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 Pfam PF03471 Transporter associated domain 342 421 3.5E-16 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 SUPERFAMILY SSF54631 208 345 2.53E-24 T 28-03-2018 CNX65_RS13355 7c518dc9233c4cfabea1105ea1349448 425 SUPERFAMILY SSF56176 339 421 9.27E-15 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS17615 48a3d34e173550dd00c204e94f116aab 117 Pfam PF13411 MerR HTH family regulatory protein 29 91 2.2E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17615 48a3d34e173550dd00c204e94f116aab 117 SMART SM00422 29 97 1.3E-8 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17615 48a3d34e173550dd00c204e94f116aab 117 Gene3D G3DSA:1.10.1660.10 18 115 4.2E-15 T 28-03-2018 CNX65_RS17615 48a3d34e173550dd00c204e94f116aab 117 SUPERFAMILY SSF46955 29 99 6.41E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Pfam PF00582 Universal stress protein family 235 348 6.7E-7 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Gene3D G3DSA:3.40.50.300 5 143 3.1E-21 T 28-03-2018 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 SUPERFAMILY SSF47384 602 680 7.85E-14 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Pfam PF13493 Domain of unknown function (DUF4118) 383 489 2.1E-27 T 28-03-2018 IPR025201 Sensor protein KdpD, transmembrane domain CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Pfam PF00512 His Kinase A (phospho-acceptor) domain 615 679 7.0E-12 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Pfam PF02702 Osmosensitive K+ channel His kinase sensor domain 5 214 2.8E-97 T 28-03-2018 IPR003852 Signal transduction histidine kinase, osmosensitive K+ channel sensor, N-terminal GO:0000155|GO:0000160|GO:0004673|GO:0016020 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Gene3D G3DSA:1.10.287.130 597 676 4.7E-12 T 28-03-2018 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 PRINTS PR00344 Bacterial sensor protein C-terminal signature 775 789 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 PRINTS PR00344 Bacterial sensor protein C-terminal signature 808 826 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 PRINTS PR00344 Bacterial sensor protein C-terminal signature 832 845 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 PRINTS PR00344 Bacterial sensor protein C-terminal signature 793 803 8.4E-12 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 723 846 4.5E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 SUPERFAMILY SSF52402 235 356 4.66E-13 T 28-03-2018 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 SMART SM00388 612 680 6.6E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Gene3D G3DSA:3.40.50.620 230 362 1.7E-15 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Gene3D G3DSA:3.30.565.10 685 849 9.9E-30 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 Gene3D G3DSA:1.20.120.620 382 481 4.2E-27 T 28-03-2018 CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 SMART SM00387 721 848 2.1E-24 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16460 ca206c6105745a15be233bee4d136728 854 SUPERFAMILY SSF55874 669 846 4.06E-32 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS17760 28b51de3497d74050845d7359a19056e 192 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 9 102 7.8E-11 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS17760 28b51de3497d74050845d7359a19056e 192 Gene3D G3DSA:2.30.110.10 1 135 6.7E-22 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS17760 28b51de3497d74050845d7359a19056e 192 SUPERFAMILY SSF50475 8 129 2.7E-11 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 SUPERFAMILY SSF51735 6 242 2.03E-78 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 3.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.1E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 Gene3D G3DSA:3.40.50.720 3 47 1.1E-12 T 28-03-2018 CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 Gene3D G3DSA:3.40.50.720 48 244 1.7E-58 T 28-03-2018 CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 241 2.5E-62 T 28-03-2018 CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 6.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 226 6.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 6.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 6.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 6.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 6.5E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02120 151ec4492a87b049807cf58236d9de66 245 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 8 199 6.4E-4 T 28-03-2018 CNX65_RS12395 d48c9d44088df33d2e7a51b66149513e 267 Pfam PF08021 Siderophore-interacting FAD-binding domain 17 127 1.2E-29 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CNX65_RS12395 d48c9d44088df33d2e7a51b66149513e 267 SUPERFAMILY SSF63380 5 133 2.06E-9 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS12395 d48c9d44088df33d2e7a51b66149513e 267 Gene3D G3DSA:3.40.50.80 128 266 1.7E-42 T 28-03-2018 CNX65_RS12395 d48c9d44088df33d2e7a51b66149513e 267 Gene3D G3DSA:2.40.30.10 5 127 2.4E-28 T 28-03-2018 CNX65_RS12395 d48c9d44088df33d2e7a51b66149513e 267 Pfam PF04954 Siderophore-interacting protein 134 243 4.6E-33 T 28-03-2018 IPR007037 Siderophore-interacting protein CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 Gene3D G3DSA:3.30.420.40 1 171 2.9E-28 T 28-03-2018 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 Pfam PF00012 Hsp70 protein 89 345 8.8E-29 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 Gene3D G3DSA:3.30.420.40 172 334 2.4E-24 T 28-03-2018 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 SUPERFAMILY SSF53067 3 156 2.41E-22 T 28-03-2018 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 PRINTS PR00301 70kDa heat shock protein signature 2 15 2.8E-8 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 PRINTS PR00301 70kDa heat shock protein signature 172 182 2.8E-8 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 PRINTS PR00301 70kDa heat shock protein signature 304 320 2.8E-8 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 PRINTS PR00301 70kDa heat shock protein signature 30 42 2.8E-8 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS07010 3c41f637401893e5d2484fc171cd1f02 660 SUPERFAMILY SSF53067 162 346 2.11E-32 T 28-03-2018 CNX65_RS19420 7cbf58fdddaeade0a6fd13c7d4e4dc2d 136 Gene3D G3DSA:3.40.50.2300 3 136 1.1E-36 T 28-03-2018 CNX65_RS19420 7cbf58fdddaeade0a6fd13c7d4e4dc2d 136 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 128 4.8E-23 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS19420 7cbf58fdddaeade0a6fd13c7d4e4dc2d 136 SUPERFAMILY SSF52788 4 128 1.23E-35 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS19420 7cbf58fdddaeade0a6fd13c7d4e4dc2d 136 SMART SM00226 5 130 1.7E-41 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS26785 d8bf6aa34ac612e50d109c4241d8eb26 407 Gene3D G3DSA:2.20.28.20 3 29 0.0044 T 28-03-2018 CNX65_RS26785 d8bf6aa34ac612e50d109c4241d8eb26 407 SUPERFAMILY SSF49785 276 404 6.8E-8 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS26785 d8bf6aa34ac612e50d109c4241d8eb26 407 Gene3D G3DSA:2.60.120.260 268 406 2.0E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS26785 d8bf6aa34ac612e50d109c4241d8eb26 407 Gene3D G3DSA:4.10.1060.10 152 204 2.7E-4 T 28-03-2018 CNX65_RS18970 9f3b174300da7d7928e899a017dfec33 208 Gene3D G3DSA:3.90.79.10 1 131 1.7E-17 T 28-03-2018 CNX65_RS18970 9f3b174300da7d7928e899a017dfec33 208 SUPERFAMILY SSF55811 5 133 1.42E-17 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS18970 9f3b174300da7d7928e899a017dfec33 208 Gene3D G3DSA:1.10.10.10 143 207 0.0012 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 SUPERFAMILY SSF46689 10 91 3.39E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 69 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 5.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 5.5E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 Gene3D G3DSA:1.10.357.10 82 202 5.9E-34 T 28-03-2018 CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 Gene3D G3DSA:1.10.260.40 47 81 1.3E-11 T 28-03-2018 CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 Gene3D G3DSA:1.10.10.60 4 46 9.4E-18 T 28-03-2018 CNX65_RS27965 fc10c12e75e608bea24c7914ec497fd6 220 SUPERFAMILY SSF48498 94 200 1.48E-27 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS08890 a439171fca95d2f5006c60aed9d70d2a 1193 TIGRFAM TIGR02257 cobalto_cobN: cobaltochelatase, CobN subunit 38 1186 0.0 T 28-03-2018 IPR011953 Cobaltochelatase, CobN subunit GO:0009236|GO:0051116 CNX65_RS08890 a439171fca95d2f5006c60aed9d70d2a 1193 Pfam PF02514 CobN/Magnesium Chelatase 99 1173 0.0 T 28-03-2018 IPR003672 CobN/magnesium chelatase GO:0009058 CNX65_RS26075 ec1ed7e7fbe6eec3496fd589048c59e9 105 Gene3D G3DSA:1.10.8.50 48 105 3.7E-7 T 28-03-2018 CNX65_RS26075 ec1ed7e7fbe6eec3496fd589048c59e9 105 PIRSF PIRSF002134 40 104 1.2E-5 T 28-03-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS26075 ec1ed7e7fbe6eec3496fd589048c59e9 105 SUPERFAMILY SSF46946 54 103 4.71E-7 T 28-03-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 CNX65_RS09145 1479253524d148d19e790b8077d1c1c4 59 Pfam PF04149 Domain of unknown function (DUF397) 5 57 2.9E-23 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 Hamap MF_01685 Ferredoxin--NADP reductase. 4 322 37.939 T 28-03-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 9.3E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 63 73 9.3E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 9.3E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 269 287 9.3E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 198 214 9.3E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 147 171 9.3E-25 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 Gene3D G3DSA:3.50.50.60 2 146 1.1E-16 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 2.1E-18 T 28-03-2018 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 259 281 2.1E-18 T 28-03-2018 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 151 169 2.1E-18 T 28-03-2018 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 287 1.2E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 Gene3D G3DSA:3.40.50.720 147 316 7.5E-30 T 28-03-2018 CNX65_RS03590 e5614235a1c613ff0649a673fdf54ee6 323 SUPERFAMILY SSF51905 2 305 6.05E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22055 aa55c4d6162dbd5aab1d01615521b2cd 511 Pfam PF00005 ABC transporter 338 439 1.1E-12 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS22055 aa55c4d6162dbd5aab1d01615521b2cd 511 Gene3D G3DSA:3.40.50.300 320 456 3.9E-25 T 28-03-2018 CNX65_RS22055 aa55c4d6162dbd5aab1d01615521b2cd 511 Pfam PF00664 ABC transporter transmembrane region 59 277 9.4E-24 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS22055 aa55c4d6162dbd5aab1d01615521b2cd 511 Gene3D G3DSA:1.20.1560.10 54 309 1.3E-41 T 28-03-2018 CNX65_RS22055 aa55c4d6162dbd5aab1d01615521b2cd 511 SUPERFAMILY SSF52540 323 458 4.21E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22055 aa55c4d6162dbd5aab1d01615521b2cd 511 SUPERFAMILY SSF90123 56 307 4.84E-44 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS20105 4d08ded1f64c93ab1740385ff6871641 450 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 223 237 - T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS20105 4d08ded1f64c93ab1740385ff6871641 450 PIRSF PIRSF001434 19 449 2.5E-121 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS20105 4d08ded1f64c93ab1740385ff6871641 450 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 28 447 4.7E-178 T 28-03-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 CNX65_RS20105 4d08ded1f64c93ab1740385ff6871641 450 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 29 447 1.4E-128 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS20105 4d08ded1f64c93ab1740385ff6871641 450 SUPERFAMILY SSF53383 26 447 6.32E-115 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS20105 4d08ded1f64c93ab1740385ff6871641 450 Gene3D G3DSA:3.40.640.10 26 314 4.5E-60 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS20105 4d08ded1f64c93ab1740385ff6871641 450 Gene3D G3DSA:3.90.1150.10 316 449 1.6E-46 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS06575 c35f11029b830ae6cee4cf13757a1cae 448 Gene3D G3DSA:3.40.190.10 189 386 7.1E-23 T 28-03-2018 CNX65_RS06575 c35f11029b830ae6cee4cf13757a1cae 448 SUPERFAMILY SSF53850 44 421 3.12E-53 T 28-03-2018 CNX65_RS06575 c35f11029b830ae6cee4cf13757a1cae 448 Gene3D G3DSA:3.40.190.10 26 188 2.2E-12 T 28-03-2018 CNX65_RS06575 c35f11029b830ae6cee4cf13757a1cae 448 Pfam PF01547 Bacterial extracellular solute-binding protein 55 359 1.4E-22 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS07390 2235575cab70747b957fb17aaac9e8d2 554 Pfam PF05683 Fumarase C-terminus 337 542 3.2E-92 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CNX65_RS07390 2235575cab70747b957fb17aaac9e8d2 554 Gene3D G3DSA:3.20.130.10 364 541 1.0E-66 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CNX65_RS07390 2235575cab70747b957fb17aaac9e8d2 554 SUPERFAMILY SSF117457 366 540 6.8E-61 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CNX65_RS07390 2235575cab70747b957fb17aaac9e8d2 554 Pfam PF05681 Fumarate hydratase (Fumerase) 54 331 8.3E-81 T 28-03-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 CNX65_RS07390 2235575cab70747b957fb17aaac9e8d2 554 PIRSF PIRSF001394 33 551 3.4E-212 T 28-03-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 CNX65_RS07390 2235575cab70747b957fb17aaac9e8d2 554 ProSitePatterns PS00163 Fumarate lyases signature. 461 470 - T 28-03-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 CNX65_RS07390 2235575cab70747b957fb17aaac9e8d2 554 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 379 542 3.5E-56 T 28-03-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 CNX65_RS34515 9e68177be90ddd0ebcf7f42cf737f757 895 SUPERFAMILY SSF48208 437 666 1.64E-42 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS34515 9e68177be90ddd0ebcf7f42cf737f757 895 SUPERFAMILY SSF48208 710 888 1.64E-42 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS34515 9e68177be90ddd0ebcf7f42cf737f757 895 Gene3D G3DSA:1.50.10.10 364 895 1.8E-95 T 28-03-2018 CNX65_RS23745 2f1f51f4f9b422a22d9828cf1fd56114 327 Gene3D G3DSA:3.40.50.1980 31 167 8.0E-17 T 28-03-2018 CNX65_RS23745 2f1f51f4f9b422a22d9828cf1fd56114 327 Gene3D G3DSA:3.40.50.1980 168 324 2.4E-38 T 28-03-2018 CNX65_RS23745 2f1f51f4f9b422a22d9828cf1fd56114 327 Pfam PF01497 Periplasmic binding protein 51 300 8.1E-28 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS23745 2f1f51f4f9b422a22d9828cf1fd56114 327 SUPERFAMILY SSF53807 47 321 1.41E-40 T 28-03-2018 CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 SMART SM00739 2 29 3.5E-5 T 28-03-2018 IPR005824 KOW CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 SUPERFAMILY SSF50104 1 99 8.21E-31 T 28-03-2018 IPR008991 Translation protein SH3-like domain CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 Gene3D G3DSA:2.30.30.30 1 94 2.6E-33 T 28-03-2018 IPR014722 Ribosomal protein L2 domain 2 CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 104 2.9E-25 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 98 21.458 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 Pfam PF00467 KOW motif 5 36 3.3E-8 T 28-03-2018 IPR005824 KOW CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 104 4.7E-37 T 28-03-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32395 7b7d349bce0be6a29328688cf5004055 104 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 28-03-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS23075 7275d2e7151a7227f1f743eae70ab254 222 SUPERFAMILY SSF48371 9 198 1.25E-13 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS23075 7275d2e7151a7227f1f743eae70ab254 222 Gene3D G3DSA:1.25.40.70 128 196 0.18 T 28-03-2018 CNX65_RS23075 7275d2e7151a7227f1f743eae70ab254 222 Gene3D G3DSA:1.25.40.70 2 67 1.4E-5 T 28-03-2018 CNX65_RS23075 7275d2e7151a7227f1f743eae70ab254 222 Gene3D G3DSA:1.25.40.70 68 127 0.0028 T 28-03-2018 CNX65_RS16115 b507f880658d2de30792bca26db24894 88 Pfam PF17195 Protein of unknown function (DUF5132) 20 65 1.8E-20 T 28-03-2018 IPR033456 Protein of unknown function DUF5132 CNX65_RS33955 2d4ed096cbddc534d223fb125f03871b 339 SUPERFAMILY SSF51735 145 302 3.54E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS33955 2d4ed096cbddc534d223fb125f03871b 339 Pfam PF16912 Glucose dehydrogenase C-terminus 144 338 3.6E-49 T 28-03-2018 IPR031640 Glucose dehydrogenase, C-terminal KEGG: 00030+1.1.1.47 CNX65_RS33955 2d4ed096cbddc534d223fb125f03871b 339 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 137 5.9E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS33955 2d4ed096cbddc534d223fb125f03871b 339 Gene3D G3DSA:3.90.180.10 4 168 5.4E-20 T 28-03-2018 CNX65_RS33955 2d4ed096cbddc534d223fb125f03871b 339 Gene3D G3DSA:3.40.50.720 169 287 7.7E-13 T 28-03-2018 CNX65_RS33955 2d4ed096cbddc534d223fb125f03871b 339 SUPERFAMILY SSF50129 24 182 1.11E-22 T 28-03-2018 IPR011032 GroES-like CNX65_RS09545 bb45275c331aa429b40a0a99cb5f696a 155 Gene3D G3DSA:3.40.50.620 1 147 3.2E-33 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS09545 bb45275c331aa429b40a0a99cb5f696a 155 Pfam PF00582 Universal stress protein family 5 135 3.8E-28 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS09545 bb45275c331aa429b40a0a99cb5f696a 155 PRINTS PR01438 Universal stress protein signature 113 135 1.9E-17 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS09545 bb45275c331aa429b40a0a99cb5f696a 155 PRINTS PR01438 Universal stress protein signature 3 21 1.9E-17 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS09545 bb45275c331aa429b40a0a99cb5f696a 155 PRINTS PR01438 Universal stress protein signature 95 107 1.9E-17 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS09545 bb45275c331aa429b40a0a99cb5f696a 155 SUPERFAMILY SSF52402 5 137 6.53E-32 T 28-03-2018 CNX65_RS30015 8062ab567720859f3b3042c9ca74d44f 288 Gene3D G3DSA:3.30.2140.10 163 273 6.7E-12 T 28-03-2018 CNX65_RS30015 8062ab567720859f3b3042c9ca74d44f 288 Gene3D G3DSA:3.30.2140.10 2 154 5.9E-30 T 28-03-2018 CNX65_RS30015 8062ab567720859f3b3042c9ca74d44f 288 Pfam PF00797 N-acetyltransferase 23 259 2.1E-37 T 28-03-2018 IPR001447 Arylamine N-acetyltransferase GO:0008152|GO:0016407 KEGG: 00232+2.3.1.5|KEGG: 00633+2.3.1.5|KEGG: 00983+2.3.1.5|Reactome: R-HSA-156582 CNX65_RS30015 8062ab567720859f3b3042c9ca74d44f 288 SUPERFAMILY SSF54001 5 267 8.24E-45 T 28-03-2018 CNX65_RS23475 0bee022b380b162f260509fb1bad687b 271 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 262 4.9E-9 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS23475 0bee022b380b162f260509fb1bad687b 271 PIRSF PIRSF037116 1 256 6.3E-58 T 28-03-2018 IPR012700 Phosphonate C-P lyase system, PhnK CNX65_RS23475 0bee022b380b162f260509fb1bad687b 271 Pfam PF00005 ABC transporter 21 178 2.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS23475 0bee022b380b162f260509fb1bad687b 271 Gene3D G3DSA:3.40.50.300 1 269 2.7E-72 T 28-03-2018 CNX65_RS23475 0bee022b380b162f260509fb1bad687b 271 SUPERFAMILY SSF52540 4 250 2.87E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23475 0bee022b380b162f260509fb1bad687b 271 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS23475 0bee022b380b162f260509fb1bad687b 271 SMART SM00382 29 228 2.0E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 91 102 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 289 316 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 338 347 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 154 169 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 137 153 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 317 332 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 271 282 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 190 212 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00359 B-class P450 signature 347 358 1.3E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 SUPERFAMILY SSF48264 5 400 2.23E-99 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 Gene3D G3DSA:1.10.630.10 4 400 6.2E-83 T 28-03-2018 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 Pfam PF00067 Cytochrome P450 268 368 5.6E-20 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00385 P450 superfamily signature 347 358 4.8E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00385 P450 superfamily signature 338 347 4.8E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00385 P450 superfamily signature 236 253 4.8E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21220 3949d78b94e77730307b48a47975a46d 400 PRINTS PR00385 P450 superfamily signature 271 282 4.8E-5 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS29855 c5e5337eec114a99cfbfc9b6849adfbc 264 SMART SM00382 23 246 3.7E-8 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS29855 c5e5337eec114a99cfbfc9b6849adfbc 264 SUPERFAMILY SSF52540 2 231 4.34E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29855 c5e5337eec114a99cfbfc9b6849adfbc 264 Gene3D G3DSA:3.40.50.300 1 248 3.2E-42 T 28-03-2018 CNX65_RS29855 c5e5337eec114a99cfbfc9b6849adfbc 264 Pfam PF00005 ABC transporter 16 165 9.3E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS24830 58f8169ab05a85158116b9caff882db2 251 Pfam PF12697 Alpha/beta hydrolase family 23 234 2.9E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS24830 58f8169ab05a85158116b9caff882db2 251 Gene3D G3DSA:3.40.50.1820 1 249 1.8E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24830 58f8169ab05a85158116b9caff882db2 251 SUPERFAMILY SSF53474 4 123 6.71E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24830 58f8169ab05a85158116b9caff882db2 251 SUPERFAMILY SSF53474 154 240 6.71E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 Gene3D G3DSA:3.90.780.10 386 574 1.3E-50 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 Pfam PF00149 Calcineurin-like phosphoesterase 44 293 3.8E-7 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 Gene3D G3DSA:3.60.21.10 31 385 6.5E-67 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 SUPERFAMILY SSF55816 371 574 9.16E-48 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 Pfam PF02872 5'-nucleotidase, C-terminal domain 374 538 9.2E-38 T 28-03-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 PRINTS PR01607 Apyrase family signature 307 327 2.9E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 PRINTS PR01607 Apyrase family signature 241 258 2.9E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 PRINTS PR01607 Apyrase family signature 437 460 2.9E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 PRINTS PR01607 Apyrase family signature 41 59 2.9E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 PRINTS PR01607 Apyrase family signature 276 299 2.9E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 PRINTS PR01607 Apyrase family signature 512 531 2.9E-20 T 28-03-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 CNX65_RS00720 951a1fddb664045c09f509f9501bad1d 575 SUPERFAMILY SSF56300 38 371 5.61E-62 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS21340 caf5870093ca747015bf43e9f27f6fbb 406 Pfam PF01761 3-dehydroquinate synthase 87 335 4.2E-58 T 28-03-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 CNX65_RS21340 caf5870093ca747015bf43e9f27f6fbb 406 Gene3D G3DSA:1.20.1090.10 188 387 1.5E-36 T 28-03-2018 CNX65_RS21340 caf5870093ca747015bf43e9f27f6fbb 406 Gene3D G3DSA:3.40.50.1970 23 187 3.4E-35 T 28-03-2018 CNX65_RS21340 caf5870093ca747015bf43e9f27f6fbb 406 SUPERFAMILY SSF56796 24 379 6.41E-77 T 28-03-2018 CNX65_RS10170 5f64869c099ff47876abdb94d113b4ed 136 Pfam PF03668 P-loop ATPase protein family 2 109 2.1E-13 T 28-03-2018 IPR005337 RapZ-like family GO:0005524 CNX65_RS19940 04b0a53bb2b2c8d09f382ab13d0619b9 366 Pfam PF01546 Peptidase family M20/M25/M40 67 362 1.8E-21 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS19940 04b0a53bb2b2c8d09f382ab13d0619b9 366 SUPERFAMILY SSF55031 172 267 8.72E-17 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS19940 04b0a53bb2b2c8d09f382ab13d0619b9 366 SUPERFAMILY SSF53187 2 181 2.26E-36 T 28-03-2018 CNX65_RS19940 04b0a53bb2b2c8d09f382ab13d0619b9 366 SUPERFAMILY SSF53187 291 365 2.26E-36 T 28-03-2018 CNX65_RS19940 04b0a53bb2b2c8d09f382ab13d0619b9 366 Gene3D G3DSA:3.40.630.10 2 366 5.7E-45 T 28-03-2018 CNX65_RS19940 04b0a53bb2b2c8d09f382ab13d0619b9 366 Pfam PF07687 Peptidase dimerisation domain 169 263 1.0E-14 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS19940 04b0a53bb2b2c8d09f382ab13d0619b9 366 PIRSF PIRSF037238 1 366 5.0E-109 T 28-03-2018 IPR017150 Peptidase M20, glutamate carboxypeptidase CNX65_RS15380 e5e4be175ab0ca770fd439bee976e505 137 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 51 121 4.0E-4 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS15380 e5e4be175ab0ca770fd439bee976e505 137 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 54 81 1.1E-13 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 CNX65_RS15380 e5e4be175ab0ca770fd439bee976e505 137 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 106 122 1.1E-13 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 CNX65_RS15380 e5e4be175ab0ca770fd439bee976e505 137 PRINTS PR00294 Streptomyces subtilisin inhibitor signature 89 105 1.1E-13 T 28-03-2018 IPR000691 Proteinase inhibitor I16, Streptomyces subtilisin-type inhibitor GO:0004867 CNX65_RS15380 e5e4be175ab0ca770fd439bee976e505 137 Gene3D G3DSA:3.30.350.10 21 131 3.5E-25 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS15380 e5e4be175ab0ca770fd439bee976e505 137 SUPERFAMILY SSF55399 43 130 4.84E-26 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS15380 e5e4be175ab0ca770fd439bee976e505 137 Pfam PF00720 Subtilisin inhibitor-like 47 117 1.7E-19 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS06795 85c5ea49b43b24ce28570c619d4cd0fb 200 SUPERFAMILY SSF81452 9 198 1.15E-55 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS06795 85c5ea49b43b24ce28570c619d4cd0fb 200 Pfam PF00510 Cytochrome c oxidase subunit III 16 198 9.0E-26 T 28-03-2018 IPR000298 Cytochrome c oxidase-like subunit III GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS06795 85c5ea49b43b24ce28570c619d4cd0fb 200 Gene3D G3DSA:1.20.120.80 16 200 5.7E-55 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Pfam PF00698 Acyl transferase domain 393 503 6.6E-17 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Gene3D G3DSA:3.40.366.10 504 569 0.13 T 28-03-2018 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 SUPERFAMILY SSF52151 392 549 1.96E-21 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 SMART SM00825 Beta-ketoacyl synthase 32 289 1.4E-20 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Pfam PF08990 Erythronolide synthase docking 3 20 1.3E-6 T 28-03-2018 IPR015083 Polyketide synthase, docking domain GO:0016740|GO:0048037 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Pfam PF16197 Ketoacyl-synthetase C-terminal extension 252 356 1.5E-8 T 28-03-2018 IPR032821 Ketoacyl-synthetase, C-terminal extension Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 130 146 - T 28-03-2018 IPR018201 Beta-ketoacyl synthase, active site CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Gene3D G3DSA:3.40.47.10 240 287 8.7E-5 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 SUPERFAMILY SSF53901 27 237 5.6E-34 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Gene3D G3DSA:3.40.366.10 387 503 8.4E-24 T 28-03-2018 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 394 710 8.8E-5 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 39 168 4.7E-29 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Gene3D G3DSA:3.40.47.10 5 169 1.9E-27 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 Gene3D G3DSA:3.40.47.10 170 205 0.011 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS21815 de2231b7b6e0db33e44535394f5f5e8e 826 SUPERFAMILY SSF51735 613 792 9.84E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30645 68d4776f4708f6524adbe2d7300c0c3d 529 Gene3D G3DSA:2.40.110.10 173 269 8.3E-24 T 28-03-2018 CNX65_RS30645 68d4776f4708f6524adbe2d7300c0c3d 529 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 281 424 1.0E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS30645 68d4776f4708f6524adbe2d7300c0c3d 529 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 178 270 3.1E-17 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS30645 68d4776f4708f6524adbe2d7300c0c3d 529 Gene3D G3DSA:1.20.140.10 270 437 2.7E-28 T 28-03-2018 CNX65_RS30645 68d4776f4708f6524adbe2d7300c0c3d 529 SUPERFAMILY SSF47203 286 432 5.64E-35 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS30645 68d4776f4708f6524adbe2d7300c0c3d 529 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 383 402 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS30645 68d4776f4708f6524adbe2d7300c0c3d 529 SUPERFAMILY SSF56645 55 290 4.71E-41 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS34440 ef417782b888339865c62b6337da04f6 185 SUPERFAMILY SSF88723 5 111 7.57E-8 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS34440 ef417782b888339865c62b6337da04f6 185 Gene3D G3DSA:3.40.50.1010 4 141 6.1E-9 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS34440 ef417782b888339865c62b6337da04f6 185 Pfam PF13470 PIN domain 5 108 9.6E-12 T 28-03-2018 IPR002716 PIN domain CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 1253 1286 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 977 1010 180.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 1207 1240 22.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 1299 1332 190.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 793 826 42.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 747 780 14.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 701 734 150.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 1161 1194 52.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SMART SM00028 1115 1148 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SUPERFAMILY SSF52540 242 351 1.32E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:3.40.50.300 168 395 2.6E-4 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SUPERFAMILY SSF50494 7 170 9.52E-13 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:1.20.1250.10 871 961 3.4E-12 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:1.20.1250.10 779 870 2.7E-13 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:1.20.1250.10 1054 1143 2.6E-12 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:1.20.1250.10 1239 1334 7.6E-15 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:1.20.1250.10 1144 1238 3.2E-16 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:1.20.1250.10 962 1053 1.2E-12 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:1.20.1250.10 674 778 6.6E-17 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Gene3D G3DSA:2.40.10.10 3 84 4.5E-6 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 746 780 0.0014 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 1114 1151 0.0013 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 930 967 5.3E-4 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 792 829 3.2E-4 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 1160 1194 0.0089 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 976 1012 0.0014 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 884 921 5.3E-4 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 1252 1286 0.0049 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 1022 1059 3.4E-4 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 1068 1105 4.5E-4 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 700 734 0.001 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 Pfam PF13374 Tetratricopeptide repeat 1206 1240 0.0049 T 28-03-2018 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SUPERFAMILY SSF48452 790 952 5.69E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SUPERFAMILY SSF48452 954 1283 8.79E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS33640 ca0611ab70d266f1e3b97606d3d4da9c 1366 SUPERFAMILY SSF48452 751 817 8.79E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13240 8826d6531fb7b2d629d1a3c7359bb6e5 279 SUPERFAMILY SSF51735 2 250 3.0E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13240 8826d6531fb7b2d629d1a3c7359bb6e5 279 Pfam PF13460 NAD(P)H-binding 6 177 2.2E-20 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13240 8826d6531fb7b2d629d1a3c7359bb6e5 279 Gene3D G3DSA:3.40.50.720 1 148 8.5E-20 T 28-03-2018 CNX65_RS11705 2655d7fbff05678fabc58b2d8d28eb68 411 Pfam PF01565 FAD binding domain 17 142 4.7E-18 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS11705 2655d7fbff05678fabc58b2d8d28eb68 411 Gene3D G3DSA:3.30.465.10 63 188 2.3E-19 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS11705 2655d7fbff05678fabc58b2d8d28eb68 411 Pfam PF04030 D-arabinono-1,4-lactone oxidase 280 404 8.6E-19 T 28-03-2018 IPR007173 D-arabinono-1,4-lactone oxidase GO:0003885|GO:0016020|GO:0055114 CNX65_RS11705 2655d7fbff05678fabc58b2d8d28eb68 411 SUPERFAMILY SSF56176 3 171 6.07E-30 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS11705 2655d7fbff05678fabc58b2d8d28eb68 411 Gene3D G3DSA:3.30.43.10 1 62 2.5E-12 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS11705 2655d7fbff05678fabc58b2d8d28eb68 411 PIRSF PIRSF000136 1 230 3.6E-35 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CNX65_RS11705 2655d7fbff05678fabc58b2d8d28eb68 411 PIRSF PIRSF000136 279 409 1.3E-7 T 28-03-2018 IPR010031 L-gulonolactone/D-arabinono-1,4-lactone oxidase GO:0016899|GO:0055114 CNX65_RS08010 0fcf55fd433e1583de2129a546cda3b8 239 TIGRFAM TIGR00017 cmk: cytidylate kinase 9 224 3.0E-57 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CNX65_RS08010 0fcf55fd433e1583de2129a546cda3b8 239 SUPERFAMILY SSF52540 9 230 6.72E-34 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08010 0fcf55fd433e1583de2129a546cda3b8 239 Pfam PF02224 Cytidylate kinase 10 227 2.4E-61 T 28-03-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CNX65_RS08010 0fcf55fd433e1583de2129a546cda3b8 239 Gene3D G3DSA:3.40.50.300 7 235 1.9E-43 T 28-03-2018 CNX65_RS08010 0fcf55fd433e1583de2129a546cda3b8 239 Hamap MF_00238 Cytidylate kinase [cmk]. 8 231 29.931 T 28-03-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 CNX65_RS02530 f73a28f985a2a515ba61623f2034b6e8 273 ProDom PD053583 TRANSMEMBRANE MEMBRANE PRECURSOR SIGNAL MB0906 RV0882/MT0905 188 252 0.002 T 28-03-2018 IPR024244 Protein of unknown function DUF2537 CNX65_RS02530 f73a28f985a2a515ba61623f2034b6e8 273 Pfam PF10801 Protein of unknown function (DUF2537) 191 269 1.9E-27 T 28-03-2018 IPR024244 Protein of unknown function DUF2537 CNX65_RS06400 43f4cf19eeeb3626b7606352a22c8e7e 249 Gene3D G3DSA:1.10.150.290 175 228 3.2E-25 T 28-03-2018 IPR023149 Trans-aconitate 2-methyltransferase, C-terminal GO:0030798 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CNX65_RS06400 43f4cf19eeeb3626b7606352a22c8e7e 249 Pfam PF13489 Methyltransferase domain 12 175 4.5E-11 T 28-03-2018 CNX65_RS06400 43f4cf19eeeb3626b7606352a22c8e7e 249 SUPERFAMILY SSF53335 11 241 3.28E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS06400 43f4cf19eeeb3626b7606352a22c8e7e 249 Gene3D G3DSA:3.40.50.150 3 174 9.7E-26 T 28-03-2018 CNX65_RS24950 82e9de079b8aede6e61efcda324c68e4 642 SMART SM00382 400 581 4.6E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS24950 82e9de079b8aede6e61efcda324c68e4 642 Pfam PF00005 ABC transporter 392 535 4.6E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS24950 82e9de079b8aede6e61efcda324c68e4 642 SUPERFAMILY SSF90123 19 325 2.22E-55 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS24950 82e9de079b8aede6e61efcda324c68e4 642 Gene3D G3DSA:3.40.50.300 364 610 4.4E-48 T 28-03-2018 CNX65_RS24950 82e9de079b8aede6e61efcda324c68e4 642 SUPERFAMILY SSF52540 370 604 6.41E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24950 82e9de079b8aede6e61efcda324c68e4 642 Gene3D G3DSA:1.20.1560.10 11 326 1.9E-46 T 28-03-2018 CNX65_RS24950 82e9de079b8aede6e61efcda324c68e4 642 Pfam PF00664 ABC transporter transmembrane region 32 299 1.6E-30 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS31225 63548ebec60a83ce51012465c25527a9 296 Pfam PF04321 RmlD substrate binding domain 6 291 2.2E-98 T 28-03-2018 IPR029903 RmlD-like substrate binding domain Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CNX65_RS31225 63548ebec60a83ce51012465c25527a9 296 SUPERFAMILY SSF51735 6 290 1.94E-80 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS31225 63548ebec60a83ce51012465c25527a9 296 Gene3D G3DSA:3.90.25.10 177 205 5.1E-8 T 28-03-2018 CNX65_RS31225 63548ebec60a83ce51012465c25527a9 296 TIGRFAM TIGR01214 rmlD: dTDP-4-dehydrorhamnose reductase 6 290 4.8E-85 T 28-03-2018 IPR005913 dTDP-4-dehydrorhamnose reductase family Reactome: R-HSA-156581|Reactome: R-HSA-5689880 CNX65_RS31225 63548ebec60a83ce51012465c25527a9 296 Gene3D G3DSA:3.40.50.720 5 176 2.5E-16 T 28-03-2018 CNX65_RS31225 63548ebec60a83ce51012465c25527a9 296 Gene3D G3DSA:3.90.25.10 206 279 1.5E-20 T 28-03-2018 CNX65_RS21430 717b330e6ea03d2aa77f437f0ccdc525 452 TIGRFAM TIGR00797 matE: MATE efflux family protein 47 416 6.0E-47 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS21430 717b330e6ea03d2aa77f437f0ccdc525 452 PIRSF PIRSF006603 4 442 5.6E-73 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS21430 717b330e6ea03d2aa77f437f0ccdc525 452 Pfam PF01554 MatE 40 182 7.8E-14 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS21430 717b330e6ea03d2aa77f437f0ccdc525 452 Pfam PF01554 MatE 245 404 1.1E-17 T 28-03-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 CNX65_RS07840 342db3f385fb6bf1856ed4759b6d7730 335 SUPERFAMILY SSF52540 79 186 7.69E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07840 342db3f385fb6bf1856ed4759b6d7730 335 Gene3D G3DSA:3.40.50.300 23 209 4.4E-6 T 28-03-2018 CNX65_RS07840 342db3f385fb6bf1856ed4759b6d7730 335 Pfam PF03969 AFG1-like ATPase 41 333 2.0E-57 T 28-03-2018 IPR005654 ATPase, AFG1-like GO:0005524 CNX65_RS06815 90982e2bd8d26df726fa5b3b81d24ee7 93 Gene3D G3DSA:3.30.70.920 1 87 6.8E-18 T 28-03-2018 CNX65_RS06815 90982e2bd8d26df726fa5b3b81d24ee7 93 Pfam PF01037 Lrp/AsnC ligand binding domain 6 76 1.4E-14 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS06815 90982e2bd8d26df726fa5b3b81d24ee7 93 SUPERFAMILY SSF54909 2 77 9.52E-17 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS18710 3545ad97bd929f28d4d4dfbda3bb925e 121 Gene3D G3DSA:3.30.750.24 5 120 2.4E-20 T 28-03-2018 IPR002645 STAS domain CNX65_RS18710 3545ad97bd929f28d4d4dfbda3bb925e 121 SUPERFAMILY SSF52091 9 115 5.1E-19 T 28-03-2018 IPR002645 STAS domain CNX65_RS18710 3545ad97bd929f28d4d4dfbda3bb925e 121 Pfam PF01740 STAS domain 9 110 3.2E-14 T 28-03-2018 IPR002645 STAS domain CNX65_RS18710 3545ad97bd929f28d4d4dfbda3bb925e 121 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 8 109 6.2E-21 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS01960 fc8566c5637d8f005eafd89b14fb751e 237 SUPERFAMILY SSF143631 3 233 3.66E-55 T 28-03-2018 IPR003374 ApbE-like domain CNX65_RS01960 fc8566c5637d8f005eafd89b14fb751e 237 Pfam PF02424 ApbE family 89 217 1.2E-33 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CNX65_RS01960 fc8566c5637d8f005eafd89b14fb751e 237 Pfam PF02424 ApbE family 8 84 1.6E-9 T 28-03-2018 IPR024932 Flavin transferase ApbE GO:0017013 CNX65_RS01960 fc8566c5637d8f005eafd89b14fb751e 237 Gene3D G3DSA:3.10.520.10 6 236 1.0E-53 T 28-03-2018 CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 182 0.0022 T 28-03-2018 CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 1.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 1.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 210 230 1.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 1.3E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 16 245 1.3E-57 T 28-03-2018 CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 SUPERFAMILY SSF51735 5 246 1.58E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS22025 686334fcc0d3a7be5864bb5fdb727ee7 249 Gene3D G3DSA:3.40.50.720 2 249 5.9E-68 T 28-03-2018 CNX65_RS22815 b7b840abe075255554d4d6fdf2fc9dcf 590 SUPERFAMILY SSF52777 40 170 1.22E-13 T 28-03-2018 CNX65_RS22815 b7b840abe075255554d4d6fdf2fc9dcf 590 Gene3D G3DSA:3.30.559.10 2 183 1.3E-16 T 28-03-2018 CNX65_RS12740 91bf167b8083a3b54779a4e978361103 385 SMART SM00382 92 248 5.1E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS12740 91bf167b8083a3b54779a4e978361103 385 SUPERFAMILY SSF52540 76 285 3.59E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12740 91bf167b8083a3b54779a4e978361103 385 Gene3D G3DSA:3.40.50.300 79 244 2.6E-20 T 28-03-2018 CNX65_RS12740 91bf167b8083a3b54779a4e978361103 385 Pfam PF07728 AAA domain (dynein-related subfamily) 96 238 6.7E-35 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 Pfam PF01565 FAD binding domain 25 156 6.1E-21 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 Gene3D G3DSA:3.30.465.10 85 231 4.6E-48 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 360 74.792 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 220 356 9.9E-36 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 Gene3D G3DSA:3.30.43.10 2 75 5.7E-21 T 28-03-2018 IPR016167 FAD-binding, type 2, subdomain 1 GO:0003824|GO:0050660|GO:0055114 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 SUPERFAMILY SSF56176 12 191 4.11E-35 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 Gene3D G3DSA:3.90.78.10 239 360 1.8E-35 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 13 356 6.3E-47 T 28-03-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS33325 5e933bb350bbc6ee1b717f9cc779f5b7 360 SUPERFAMILY SSF56194 218 358 1.57E-29 T 28-03-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387 CNX65_RS14455 b04ca268cc15c1c76e0a75262cbe8418 108 Gene3D G3DSA:1.10.287.1060 1 93 2.9E-6 T 28-03-2018 CNX65_RS14455 b04ca268cc15c1c76e0a75262cbe8418 108 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 9 90 1.8E-5 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CNX65_RS05980 1a9331c5672054fe05cdbdff9dac5893 243 SUPERFAMILY SSF52266 1 88 1.25E-13 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS05980 1a9331c5672054fe05cdbdff9dac5893 243 SUPERFAMILY SSF52266 128 230 1.25E-13 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS05980 1a9331c5672054fe05cdbdff9dac5893 243 Gene3D G3DSA:3.40.50.1110 1 234 7.9E-18 T 28-03-2018 CNX65_RS05980 1a9331c5672054fe05cdbdff9dac5893 243 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 5 215 1.2E-8 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS14955 fc8e2c80fd872a1fbf05b519e57739ca 537 Gene3D G3DSA:3.40.50.1820 21 511 1.1E-35 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14955 fc8e2c80fd872a1fbf05b519e57739ca 537 Pfam PF08386 TAP-like protein 427 527 4.8E-20 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS14955 fc8e2c80fd872a1fbf05b519e57739ca 537 SUPERFAMILY SSF53474 101 155 5.65E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14955 fc8e2c80fd872a1fbf05b519e57739ca 537 SUPERFAMILY SSF53474 202 256 5.65E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14955 fc8e2c80fd872a1fbf05b519e57739ca 537 SUPERFAMILY SSF53474 355 502 5.65E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14955 fc8e2c80fd872a1fbf05b519e57739ca 537 Pfam PF00561 alpha/beta hydrolase fold 103 255 4.6E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS11510 d5cccc0f5d6e1e474aaf1d0ade15957b 399 SUPERFAMILY SSF103473 14 384 7.06E-27 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS11510 d5cccc0f5d6e1e474aaf1d0ade15957b 399 Gene3D G3DSA:1.20.1250.20 204 387 4.7E-8 T 28-03-2018 CNX65_RS11510 d5cccc0f5d6e1e474aaf1d0ade15957b 399 Pfam PF07690 Major Facilitator Superfamily 17 227 6.8E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS11510 d5cccc0f5d6e1e474aaf1d0ade15957b 399 Gene3D G3DSA:1.20.1250.20 5 203 2.9E-12 T 28-03-2018 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 Pfam PF00455 DeoR C terminal sensor domain 77 233 2.3E-44 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.9E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.9E-9 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 SUPERFAMILY SSF100950 75 234 5.76E-24 T 28-03-2018 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 Gene3D G3DSA:3.40.50.1360 73 237 1.6E-33 T 28-03-2018 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 SMART SM01134 73 234 6.8E-56 T 28-03-2018 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 SMART SM00420 6 58 5.5E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 SUPERFAMILY SSF46785 4 62 2.73E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 Pfam PF08220 DeoR-like helix-turn-helix domain 6 57 1.5E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS26435 34a31fd78615a58783368c019f1e4aef 253 Gene3D G3DSA:1.10.10.10 1 68 6.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 Gene3D G3DSA:1.10.10.60 7 63 1.5E-20 T 28-03-2018 CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 SUPERFAMILY SSF48498 88 189 3.34E-11 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 SUPERFAMILY SSF46689 4 72 6.48E-18 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 7.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 7.4E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 Gene3D G3DSA:1.10.357.10 64 196 8.5E-17 T 28-03-2018 CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 Pfam PF13305 WHG domain 100 168 6.1E-7 T 28-03-2018 IPR025996 WHG domain CNX65_RS25365 40ccc6e8cea31f5acb22a2a425812a8b 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 58 1.4E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS08500 35f43aeacbe11b02137132eb2a86ad0d 287 Gene3D G3DSA:3.40.50.150 7 274 9.3E-46 T 28-03-2018 CNX65_RS08500 35f43aeacbe11b02137132eb2a86ad0d 287 Pfam PF01564 Spermine/spermidine synthase domain 54 182 3.4E-8 T 28-03-2018 CNX65_RS08500 35f43aeacbe11b02137132eb2a86ad0d 287 SUPERFAMILY SSF53335 10 240 2.7E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS21370 10eaf25aef5b025a1cd4bc4a64d8d07f 1183 Pfam PF13569 Domain of unknown function (DUF4132) 918 1099 3.2E-49 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS18580 bf0440ee37775b25627446df25dc6ff7 212 SUPERFAMILY SSF48498 80 208 2.0E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS18580 bf0440ee37775b25627446df25dc6ff7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 6.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18580 bf0440ee37775b25627446df25dc6ff7 212 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 6.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18580 bf0440ee37775b25627446df25dc6ff7 212 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 3.9E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18580 bf0440ee37775b25627446df25dc6ff7 212 Gene3D G3DSA:1.10.10.60 2 49 2.0E-19 T 28-03-2018 CNX65_RS18580 bf0440ee37775b25627446df25dc6ff7 212 Gene3D G3DSA:1.10.357.10 50 209 3.8E-13 T 28-03-2018 CNX65_RS18580 bf0440ee37775b25627446df25dc6ff7 212 SUPERFAMILY SSF46689 3 73 7.18E-19 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS24315 ea0ff9349522d950c28bb18801b4884d 383 PIRSF PIRSF006078 1 377 1.3E-107 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS24315 ea0ff9349522d950c28bb18801b4884d 383 Gene3D G3DSA:3.90.1510.10 42 276 5.9E-81 T 28-03-2018 IPR018193 Glycerate kinase, flavodoxin-like domain GO:0008887|GO:0031388 CNX65_RS24315 ea0ff9349522d950c28bb18801b4884d 383 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 374 8.7E-135 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS24315 ea0ff9349522d950c28bb18801b4884d 383 SUPERFAMILY SSF110738 1 375 2.88E-115 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS24315 ea0ff9349522d950c28bb18801b4884d 383 Pfam PF02595 Glycerate kinase family 3 373 9.0E-132 T 28-03-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 CNX65_RS30115 9802715d7561321b22bf91e7ae9c634a 285 Pfam PF13560 Helix-turn-helix domain 14 75 5.6E-13 T 28-03-2018 CNX65_RS30115 9802715d7561321b22bf91e7ae9c634a 285 SMART SM00530 18 73 4.5E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS30115 9802715d7561321b22bf91e7ae9c634a 285 SUPERFAMILY SSF47413 11 71 7.32E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS30115 9802715d7561321b22bf91e7ae9c634a 285 Gene3D G3DSA:1.10.3100.10 11 155 1.7E-13 T 28-03-2018 IPR027910 YdiL-like domain CNX65_RS32225 707ad6af713ef71462c9e0280dbdb216 96 TIGRFAM TIGR03930 WXG100_ESAT6: WXG100 family type VII secretion target 4 92 1.8E-23 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS32225 707ad6af713ef71462c9e0280dbdb216 96 Gene3D G3DSA:1.10.287.1060 1 96 1.8E-22 T 28-03-2018 CNX65_RS32225 707ad6af713ef71462c9e0280dbdb216 96 ProDom PD020150 ESAT-6-LIKE ANTIGEN ESXR CFP7 LOW WEIGHT ESXQ CFP-7 TB10.4 MOLECULAR 4 96 1.0E-4 T 28-03-2018 CNX65_RS32225 707ad6af713ef71462c9e0280dbdb216 96 Pfam PF06013 Proteins of 100 residues with WXG 4 89 1.8E-19 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS32225 707ad6af713ef71462c9e0280dbdb216 96 SUPERFAMILY SSF140453 3 96 4.19E-25 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 Gene3D G3DSA:2.40.110.10 124 221 1.1E-37 T 28-03-2018 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 SUPERFAMILY SSF56645 6 245 7.2E-84 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 10 121 1.7E-33 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 Gene3D G3DSA:1.20.140.10 222 381 2.3E-52 T 28-03-2018 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 340 359 - T 28-03-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 PIRSF PIRSF016578 1 381 2.7E-14 T 28-03-2018 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 Gene3D G3DSA:1.10.540.10 2 123 1.1E-35 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 SUPERFAMILY SSF47203 231 381 2.09E-49 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 381 1.2E-44 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS27750 be1746ef59b4877bbffae84bc0516b7e 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 125 221 2.5E-26 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS05765 728a4c69c0ec1c203e2294bbc58f5b69 302 Gene3D G3DSA:3.40.50.1820 58 300 3.9E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS05765 728a4c69c0ec1c203e2294bbc58f5b69 302 SUPERFAMILY SSF53474 62 299 3.02E-28 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS05765 728a4c69c0ec1c203e2294bbc58f5b69 302 Pfam PF00756 Putative esterase 74 258 2.0E-10 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CNX65_RS03885 c98d074b69b53e85fe979c6ce486ad38 268 Pfam PF07848 PaaX-like protein 2 65 3.3E-14 T 28-03-2018 IPR012906 PaaX-like, N-terminal CNX65_RS03885 c98d074b69b53e85fe979c6ce486ad38 268 PIRSF PIRSF020623 1 267 3.6E-64 T 28-03-2018 IPR011965 Phenylacetic acid degradation operon negative regulatory protein PaaX GO:0006351 CNX65_RS03885 c98d074b69b53e85fe979c6ce486ad38 268 Gene3D G3DSA:1.10.10.10 1 84 3.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03885 c98d074b69b53e85fe979c6ce486ad38 268 Pfam PF08223 PaaX-like protein C-terminal domain 161 253 3.2E-24 T 28-03-2018 IPR013225 PaaX-like, C-terminal CNX65_RS13955 f5229b2eb4a9cf24a386b6f93582b69a 301 Gene3D G3DSA:1.10.10.10 22 124 4.9E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13955 f5229b2eb4a9cf24a386b6f93582b69a 301 SUPERFAMILY SSF46689 27 89 2.51E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS13955 f5229b2eb4a9cf24a386b6f93582b69a 301 Pfam PF01418 Helix-turn-helix domain, rpiR family 31 85 2.7E-7 T 28-03-2018 IPR000281 Helix-turn-helix protein RpiR GO:0003700|GO:0006355 CNX65_RS13955 f5229b2eb4a9cf24a386b6f93582b69a 301 SUPERFAMILY SSF53697 123 270 2.67E-19 T 28-03-2018 CNX65_RS13955 f5229b2eb4a9cf24a386b6f93582b69a 301 Pfam PF01380 SIS domain 143 273 1.2E-11 T 28-03-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 CNX65_RS13955 f5229b2eb4a9cf24a386b6f93582b69a 301 Gene3D G3DSA:3.40.50.10490 125 290 7.1E-21 T 28-03-2018 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 Gene3D G3DSA:2.30.110.10 15 219 7.8E-71 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 39 124 5.1E-20 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 TIGRFAM TIGR00558 pdxH: pyridoxamine 5'-phosphate oxidase 4 219 3.2E-75 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 Pfam PF10590 Pyridoxine 5'-phosphate oxidase C-terminal dimerisation region 179 219 1.6E-16 T 28-03-2018 IPR019576 Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 SUPERFAMILY SSF50475 17 219 2.69E-63 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 PIRSF PIRSF000190 2 219 6.3E-78 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 ProSitePatterns PS01064 Pyridoxamine 5'-phosphate oxidase signature. 189 202 - T 28-03-2018 IPR019740 Pyridoxamine 5'-phosphate oxidase, conserved site GO:0016638|GO:0055114 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS02550 9e3b398254d0833a07bc45ee72858e14 219 Hamap MF_01629 Pyridoxine/pyridoxamine 5'-phosphate oxidase [pdxH]. 16 219 36.34 T 28-03-2018 IPR000659 Pyridoxamine 5'-phosphate oxidase GO:0004733|GO:0008615|GO:0010181 KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS02995 1aae6f45f6097389c14223d30f3a5afd 210 Gene3D G3DSA:3.40.109.10 1 210 4.4E-40 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS02995 1aae6f45f6097389c14223d30f3a5afd 210 Pfam PF00881 Nitroreductase family 9 173 1.4E-25 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS02995 1aae6f45f6097389c14223d30f3a5afd 210 SUPERFAMILY SSF55469 1 205 2.36E-45 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS02995 1aae6f45f6097389c14223d30f3a5afd 210 TIGRFAM TIGR02476 BluB: 5,6-dimethylbenzimidazole synthase 2 199 2.5E-65 T 28-03-2018 IPR012825 5,6-dimethylbenzimidazole synthase BluB KEGG: 00740+1.13.11.79|MetaCyc: PWY-5508|MetaCyc: PWY-5523 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 TIGRFAM TIGR00510 lipA: lipoyl synthase 17 305 5.5E-100 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 Pfam PF04055 Radical SAM superfamily 80 235 4.1E-15 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 Gene3D G3DSA:3.20.20.70 25 321 2.1E-25 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 Hamap MF_00206 Lipoyl synthase [lipA]. 1 307 140.758 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 24 60 1.3E-6 T 28-03-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 PIRSF PIRSF005963 5 318 3.0E-122 T 28-03-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 SUPERFAMILY SSF102114 35 303 3.27E-63 T 28-03-2018 CNX65_RS06625 7c6637c34defa3524c336935c408d737 334 SMART SM00729 71 277 1.4E-18 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS01650 1e82422305f04d18ec1924b11c99cc4f 149 PIRSF PIRSF034110 5 145 1.8E-24 T 28-03-2018 IPR009593 Protein of unknown function DUF1203 CNX65_RS01650 1e82422305f04d18ec1924b11c99cc4f 149 Pfam PF06718 Protein of unknown function (DUF1203) 31 143 1.0E-29 T 28-03-2018 IPR009593 Protein of unknown function DUF1203 CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 Gene3D G3DSA:3.40.50.980 11 182 1.3E-35 T 28-03-2018 CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 Gene3D G3DSA:2.30.38.10 332 419 5.3E-25 T 28-03-2018 CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 SUPERFAMILY SSF56801 9 518 1.57E-147 T 28-03-2018 CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 177 188 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 Pfam PF00501 AMP-binding enzyme 21 426 2.0E-98 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 435 508 6.0E-21 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 Gene3D G3DSA:3.40.50.980 183 331 1.3E-51 T 28-03-2018 CNX65_RS20600 eeeebafd35e21e34f21c82420d7e6574 519 Gene3D G3DSA:3.30.300.30 420 519 6.6E-29 T 28-03-2018 CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 Gene3D G3DSA:3.90.180.10 1 156 1.4E-38 T 28-03-2018 CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 Pfam PF00107 Zinc-binding dehydrogenase 159 250 7.0E-22 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 Gene3D G3DSA:3.90.180.10 254 346 2.8E-5 T 28-03-2018 CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 SUPERFAMILY SSF50129 19 147 1.98E-27 T 28-03-2018 IPR011032 GroES-like CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 Gene3D G3DSA:3.40.50.720 157 253 4.2E-22 T 28-03-2018 CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 SUPERFAMILY SSF51735 121 309 1.43E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 SMART SM00829 20 343 7.4E-15 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS03865 bfee4484048224f621b501fe6327704f 347 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 36 95 3.7E-5 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS18565 6705c0a30e40ae6745ece66bf30e0ecd 226 Pfam PF00072 Response regulator receiver domain 5 115 1.9E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS18565 6705c0a30e40ae6745ece66bf30e0ecd 226 PIRSF PIRSF006171 1 226 1.3E-64 T 28-03-2018 IPR024187 Signal transduction response regulator, citrate/malate metabolism GO:0001071|GO:0003677|GO:0005737|GO:0009605 CNX65_RS18565 6705c0a30e40ae6745ece66bf30e0ecd 226 SUPERFAMILY SSF52172 3 158 8.25E-37 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS18565 6705c0a30e40ae6745ece66bf30e0ecd 226 SMART SM00448 2 116 9.1E-30 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS18565 6705c0a30e40ae6745ece66bf30e0ecd 226 Gene3D G3DSA:1.10.10.10 154 226 2.2E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18565 6705c0a30e40ae6745ece66bf30e0ecd 226 Gene3D G3DSA:3.40.50.2300 1 149 2.0E-34 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 322 4.2E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 SUPERFAMILY SSF51905 2 331 8.53E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PIRSF PIRSF000350 1 457 2.3E-82 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 SUPERFAMILY SSF55424 338 460 6.36E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 403 418 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 425 445 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 136 145 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 2.8E-63 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 Gene3D G3DSA:3.50.50.60 1 154 4.7E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 Gene3D G3DSA:3.40.50.720 155 329 3.0E-36 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 Gene3D G3DSA:3.30.390.30 330 457 1.1E-38 T 28-03-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain GO:0016491|GO:0050660|GO:0055114 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 3.3E-35 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 3.3E-35 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 3.3E-35 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 133 151 3.3E-35 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 3.3E-35 T 28-03-2018 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 450 3.0E-35 T 28-03-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 460 2.4E-167 T 28-03-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 CNX65_RS30260 c1e934a77ed7b2e91655cfc4216f3657 461 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 28-03-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 7.0E-41 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 313 331 7.0E-41 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 280 295 7.0E-41 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 311 7.0E-41 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 331 347 7.0E-41 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 7.0E-41 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 SUPERFAMILY SSF51905 5 174 3.48E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 SUPERFAMILY SSF51905 267 376 3.48E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 Pfam PF01494 FAD binding domain 5 343 1.0E-72 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 Gene3D G3DSA:3.30.9.10 160 288 3.6E-20 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 Gene3D G3DSA:3.30.9.10 289 369 3.7E-18 T 28-03-2018 CNX65_RS16190 d66f0b0ac61055b202977486d37bd2e0 511 Gene3D G3DSA:3.50.50.60 2 159 4.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32410 5f42e0e115107f66179966155e314f6c 82 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 5 64 16.735 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32410 5f42e0e115107f66179966155e314f6c 82 SUPERFAMILY SSF46561 7 67 3.53E-21 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32410 5f42e0e115107f66179966155e314f6c 82 Pfam PF00831 Ribosomal L29 protein 8 64 5.1E-23 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32410 5f42e0e115107f66179966155e314f6c 82 Gene3D G3DSA:1.10.287.310 6 68 2.7E-22 T 28-03-2018 CNX65_RS32410 5f42e0e115107f66179966155e314f6c 82 TIGRFAM TIGR00012 L29: ribosomal protein uL29 9 64 2.8E-18 T 28-03-2018 IPR001854 Ribosomal protein L29/L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS31420 e693ef8bbd6587161f5060e356f85828 291 Gene3D G3DSA:3.40.50.1000 2 287 2.1E-21 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS31420 e693ef8bbd6587161f5060e356f85828 291 SUPERFAMILY SSF56784 5 190 1.62E-24 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS31420 e693ef8bbd6587161f5060e356f85828 291 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 89 179 3.7E-9 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS31420 e693ef8bbd6587161f5060e356f85828 291 Pfam PF00702 haloacid dehalogenase-like hydrolase 61 177 1.7E-9 T 28-03-2018 CNX65_RS08405 f1eb35b62457af18a58f531bebe33c52 221 SUPERFAMILY SSF81606 2 217 1.23E-53 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS08405 f1eb35b62457af18a58f531bebe33c52 221 SMART SM00332 1 215 7.4E-21 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS08405 f1eb35b62457af18a58f531bebe33c52 221 SMART SM00331 9 217 1.5E-24 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS08405 f1eb35b62457af18a58f531bebe33c52 221 Gene3D G3DSA:3.60.40.10 1 218 3.6E-38 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS08405 f1eb35b62457af18a58f531bebe33c52 221 Pfam PF13672 Protein phosphatase 2C 15 184 2.1E-14 T 28-03-2018 CNX65_RS20210 2ff88e9f36dfbb647b5273d136f54fd8 66 Gene3D G3DSA:2.20.28.10 18 66 1.3E-4 T 28-03-2018 CNX65_RS34290 877cf4c7f6c48d7a402881e4a709feda 117 Gene3D G3DSA:1.10.287.1060 1 111 9.0E-6 T 28-03-2018 CNX65_RS29935 7374eef160ae27e90a04fc1cb6d282be 368 Pfam PF01636 Phosphotransferase enzyme family 201 283 5.8E-7 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS29935 7374eef160ae27e90a04fc1cb6d282be 368 Gene3D G3DSA:3.90.1200.10 27 361 1.8E-9 T 28-03-2018 CNX65_RS29935 7374eef160ae27e90a04fc1cb6d282be 368 SUPERFAMILY SSF56112 121 308 6.46E-16 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS25275 6241cb0accaa88b0bd4ae623d8de1fc7 243 SMART SM00882 1 209 1.8E-30 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CNX65_RS25275 6241cb0accaa88b0bd4ae623d8de1fc7 243 Pfam PF01144 Coenzyme A transferase 1 203 4.0E-37 T 28-03-2018 IPR004165 Coenzyme A transferase family I GO:0008152|GO:0008410 Reactome: R-HSA-77108 CNX65_RS25275 6241cb0accaa88b0bd4ae623d8de1fc7 243 SUPERFAMILY SSF100950 1 237 1.58E-71 T 28-03-2018 CNX65_RS25275 6241cb0accaa88b0bd4ae623d8de1fc7 243 Gene3D G3DSA:3.40.1080.10 1 242 1.1E-51 T 28-03-2018 CNX65_RS31475 df39969d45339ff6d34719e81d9e6df1 423 SUPERFAMILY SSF55031 218 335 2.39E-18 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS31475 df39969d45339ff6d34719e81d9e6df1 423 PIRSF PIRSF005962 42 423 1.6E-103 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CNX65_RS31475 df39969d45339ff6d34719e81d9e6df1 423 Gene3D G3DSA:3.40.630.10 40 423 3.7E-53 T 28-03-2018 CNX65_RS31475 df39969d45339ff6d34719e81d9e6df1 423 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 54 410 1.4E-99 T 28-03-2018 IPR017439 Amidohydrolase GO:0016787 CNX65_RS31475 df39969d45339ff6d34719e81d9e6df1 423 SUPERFAMILY SSF53187 42 233 9.61E-73 T 28-03-2018 CNX65_RS31475 df39969d45339ff6d34719e81d9e6df1 423 SUPERFAMILY SSF53187 334 422 9.61E-73 T 28-03-2018 CNX65_RS31475 df39969d45339ff6d34719e81d9e6df1 423 Pfam PF01546 Peptidase family M20/M25/M40 109 418 2.1E-28 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS19725 2425b1b90d2fee32cdd2ef1d03f084f5 197 Gene3D G3DSA:1.10.260.40 1 84 2.3E-17 T 28-03-2018 CNX65_RS19725 2425b1b90d2fee32cdd2ef1d03f084f5 197 SUPERFAMILY SSF47413 10 77 8.85E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS19725 2425b1b90d2fee32cdd2ef1d03f084f5 197 Pfam PF01381 Helix-turn-helix 17 69 1.4E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS19725 2425b1b90d2fee32cdd2ef1d03f084f5 197 SMART SM00530 16 71 7.4E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS18615 e4934047097cfff300fb4723da0aa217 328 SUPERFAMILY SSF144083 264 324 1.12E-12 T 28-03-2018 CNX65_RS18615 e4934047097cfff300fb4723da0aa217 328 Gene3D G3DSA:3.30.460.20 2 129 8.2E-25 T 28-03-2018 CNX65_RS18615 e4934047097cfff300fb4723da0aa217 328 Gene3D G3DSA:1.20.58.340 136 261 5.2E-25 T 28-03-2018 CNX65_RS18615 e4934047097cfff300fb4723da0aa217 328 SUPERFAMILY SSF143865 9 261 7.19E-57 T 28-03-2018 CNX65_RS18615 e4934047097cfff300fb4723da0aa217 328 Pfam PF01544 CorA-like Mg2+ transporter protein 31 323 4.1E-58 T 28-03-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 CNX65_RS18615 e4934047097cfff300fb4723da0aa217 328 Gene3D G3DSA:1.20.58.340 262 328 1.0E-14 T 28-03-2018 CNX65_RS09280 025e88580881a17fc95df6fe1a2b8bbf 504 Gene3D G3DSA:2.115.10.20 58 373 5.3E-50 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS09280 025e88580881a17fc95df6fe1a2b8bbf 504 Pfam PF04616 Glycosyl hydrolases family 43 63 359 1.4E-58 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS09280 025e88580881a17fc95df6fe1a2b8bbf 504 SUPERFAMILY SSF75005 59 360 4.47E-58 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS09280 025e88580881a17fc95df6fe1a2b8bbf 504 Gene3D G3DSA:2.80.10.50 374 504 1.5E-27 T 28-03-2018 CNX65_RS09280 025e88580881a17fc95df6fe1a2b8bbf 504 SUPERFAMILY SSF110221 360 502 2.75E-21 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS09280 025e88580881a17fc95df6fe1a2b8bbf 504 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 378 503 1.4E-16 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS04615 dcea07c8b779d8ab6aee18959c770431 1001 Gene3D G3DSA:1.20.120.80 163 448 7.3E-4 T 28-03-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04615 dcea07c8b779d8ab6aee18959c770431 1001 Hamap MF_01600 UPF0182 protein . 11 908 17.781 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CNX65_RS04615 dcea07c8b779d8ab6aee18959c770431 1001 Pfam PF03699 Uncharacterised protein family (UPF0182) 21 831 5.6E-268 T 28-03-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 CNX65_RS19745 f63487da301c2c039c343add6da5b3c5 144 Pfam PF13466 STAS domain 43 125 9.9E-12 T 28-03-2018 IPR002645 STAS domain CNX65_RS19745 f63487da301c2c039c343add6da5b3c5 144 Gene3D G3DSA:3.30.750.24 32 141 2.9E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS19745 f63487da301c2c039c343add6da5b3c5 144 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 36 137 2.1E-18 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS19745 f63487da301c2c039c343add6da5b3c5 144 SUPERFAMILY SSF52091 37 139 2.55E-15 T 28-03-2018 IPR002645 STAS domain CNX65_RS10770 1462dcd45c7b38cbaa8e404998760d70 501 Pfam PF07690 Major Facilitator Superfamily 20 407 6.7E-41 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS10770 1462dcd45c7b38cbaa8e404998760d70 501 SUPERFAMILY SSF103473 464 494 7.19E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS10770 1462dcd45c7b38cbaa8e404998760d70 501 SUPERFAMILY SSF103473 6 198 7.19E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS10770 1462dcd45c7b38cbaa8e404998760d70 501 SUPERFAMILY SSF103473 251 421 7.19E-64 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS10770 1462dcd45c7b38cbaa8e404998760d70 501 Gene3D G3DSA:1.20.1250.20 10 208 3.5E-30 T 28-03-2018 CNX65_RS10770 1462dcd45c7b38cbaa8e404998760d70 501 Gene3D G3DSA:1.20.1250.20 255 497 1.6E-25 T 28-03-2018 CNX65_RS07350 5b8ccad0c56ea4281a3b887b7599146a 497 Gene3D G3DSA:3.40.309.10 254 427 2.0E-21 T 28-03-2018 CNX65_RS07350 5b8ccad0c56ea4281a3b887b7599146a 497 Pfam PF00171 Aldehyde dehydrogenase family 5 438 9.7E-49 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS07350 5b8ccad0c56ea4281a3b887b7599146a 497 Gene3D G3DSA:3.40.605.10 2 253 4.7E-53 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS07350 5b8ccad0c56ea4281a3b887b7599146a 497 SUPERFAMILY SSF53720 4 491 5.37E-93 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS08705 b46073349d8b0f1f99166769a640c411 352 SUPERFAMILY SSF53448 6 240 1.13E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08705 b46073349d8b0f1f99166769a640c411 352 Gene3D G3DSA:3.90.550.10 1 298 7.7E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS08705 b46073349d8b0f1f99166769a640c411 352 Pfam PF00535 Glycosyl transferase family 2 11 135 7.2E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 SMART SM00354 14 84 1.5E-28 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 26 36 3.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 16 26 3.9E-5 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 SUPERFAMILY SSF47413 16 70 1.64E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 Gene3D G3DSA:3.40.50.2300 182 343 1.1E-52 T 28-03-2018 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 Gene3D G3DSA:3.40.50.2300 71 181 5.2E-25 T 28-03-2018 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 Pfam PF00356 Bacterial regulatory proteins, lacI family 17 61 4.4E-19 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 Pfam PF13377 Periplasmic binding protein-like domain 185 342 1.6E-34 T 28-03-2018 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 Gene3D G3DSA:1.10.10.10 5 30 6.2E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 SUPERFAMILY SSF53822 87 342 4.32E-65 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 Gene3D G3DSA:1.10.260.40 31 70 8.5E-21 T 28-03-2018 CNX65_RS08915 c076e8e9b2e9a481514672060a1b2bad 343 ProSitePatterns PS00356 LacI-type HTH domain signature. 17 35 - T 28-03-2018 CNX65_RS03270 d28f659d708c70278e67355fad38f7ef 388 Pfam PF00326 Prolyl oligopeptidase family 182 383 4.6E-14 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS03270 d28f659d708c70278e67355fad38f7ef 388 SUPERFAMILY SSF53474 127 381 9.34E-36 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03270 d28f659d708c70278e67355fad38f7ef 388 Gene3D G3DSA:3.40.50.1820 136 388 6.9E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS12540 abfd676f621dc2868cd429ca252b98fc 132 SUPERFAMILY SSF55874 43 127 4.16E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12540 abfd676f621dc2868cd429ca252b98fc 132 Pfam PF13581 Histidine kinase-like ATPase domain 24 125 1.7E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS12540 abfd676f621dc2868cd429ca252b98fc 132 Gene3D G3DSA:3.30.565.10 3 132 5.6E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS01335 275a795dbfd6907ca9df9cb02c7b1b04 162 SUPERFAMILY SSF88723 10 130 5.05E-16 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS01335 275a795dbfd6907ca9df9cb02c7b1b04 162 Pfam PF01850 PIN domain 10 128 2.9E-11 T 28-03-2018 IPR002716 PIN domain CNX65_RS01335 275a795dbfd6907ca9df9cb02c7b1b04 162 Gene3D G3DSA:3.40.50.1010 9 140 4.9E-18 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS07965 f77160ce3a2522d09ffab931ebcafc17 153 Pfam PF01575 MaoC like domain 11 121 1.2E-26 T 28-03-2018 IPR002539 MaoC-like domain CNX65_RS07965 f77160ce3a2522d09ffab931ebcafc17 153 Gene3D G3DSA:3.10.129.10 2 153 4.0E-35 T 28-03-2018 CNX65_RS07965 f77160ce3a2522d09ffab931ebcafc17 153 SUPERFAMILY SSF54637 4 149 2.12E-39 T 28-03-2018 IPR029069 HotDog domain CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 ProSitePatterns PS00622 LuxR-type HTH domain signature. 743 770 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 SUPERFAMILY SSF46894 723 782 1.02E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 Gene3D G3DSA:1.10.10.10 719 785 5.7E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 Pfam PF00196 Bacterial regulatory proteins, luxR family 729 780 2.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 SMART SM00421 726 783 6.2E-20 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 729 743 2.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 759 771 2.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 743 759 2.2E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 Gene3D G3DSA:1.25.40.10 286 718 8.1E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS02855 fbdc43e2cb79180b63f3c23ed019aa2f 788 Gene3D G3DSA:3.40.50.300 8 259 2.2E-4 T 28-03-2018 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Gene3D G3DSA:2.60.40.290 765 872 3.2E-35 T 28-03-2018 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 SMART SM00637 773 872 8.3E-43 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Pfam PF00553 Cellulose binding domain 773 872 2.7E-28 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 ProSitePatterns PS00698 Glycosyl hydrolases family 9 active sites signature 2. 732 750 - T 28-03-2018 IPR033126 Glycosyl hydrolases family 9, Asp/Glu active sites KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Pfam PF02018 Carbohydrate binding domain 55 177 1.2E-13 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Gene3D G3DSA:2.60.120.260 46 196 1.2E-26 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 SUPERFAMILY SSF49785 52 193 1.72E-32 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Gene3D G3DSA:1.50.10.10 299 764 8.5E-125 T 28-03-2018 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Gene3D G3DSA:2.60.40.10 204 294 6.2E-20 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 SUPERFAMILY SSF49384 769 874 2.3E-31 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Pfam PF00759 Glycosyl hydrolase family 9 300 755 6.8E-101 T 28-03-2018 IPR001701 Glycoside hydrolase family 9 GO:0004553|GO:0005975 KEGG: 00500+3.2.1.4|MetaCyc: PWY-6788 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 Pfam PF02927 Cellulase N-terminal ig-like domain 207 286 1.1E-19 T 28-03-2018 IPR004197 Cellulase, Ig-like domain GO:0005975|GO:0008810 CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 SUPERFAMILY SSF81296 207 294 1.68E-19 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS26580 73e3d2ae890d486f658a205d31a58498 875 SUPERFAMILY SSF48208 301 760 2.72E-128 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS06710 847a90922c56aa463343e9a0a6cbdd49 237 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 237 41.002 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06710 847a90922c56aa463343e9a0a6cbdd49 237 Pfam PF02654 Cobalamin-5-phosphate synthase 4 232 9.8E-48 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06710 847a90922c56aa463343e9a0a6cbdd49 237 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 2 234 2.4E-36 T 28-03-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS23365 4ae7ac8ee8e65b001e75baa172cd2cb3 220 Gene3D G3DSA:2.70.50.50 37 220 3.9E-45 T 28-03-2018 CNX65_RS23365 4ae7ac8ee8e65b001e75baa172cd2cb3 220 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 37 217 3.2E-28 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CNX65_RS23365 4ae7ac8ee8e65b001e75baa172cd2cb3 220 SUPERFAMILY SSF81296 37 220 2.8E-28 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS20870 4a815a63268a79f49822088854910e30 211 Gene3D G3DSA:3.40.50.1860 29 110 0.018 T 28-03-2018 CNX65_RS20870 4a815a63268a79f49822088854910e30 211 Gene3D G3DSA:3.40.50.1860 111 199 5.8E-12 T 28-03-2018 CNX65_RS28820 f6f5847a0bed2c09a26d4831725524ac 266 Pfam PF04672 S-adenosyl methyltransferase 6 264 6.2E-90 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS28820 f6f5847a0bed2c09a26d4831725524ac 266 PIRSF PIRSF017393 1 266 2.1E-96 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS28820 f6f5847a0bed2c09a26d4831725524ac 266 Gene3D G3DSA:3.40.50.150 1 265 7.4E-52 T 28-03-2018 CNX65_RS28820 f6f5847a0bed2c09a26d4831725524ac 266 SUPERFAMILY SSF53335 9 250 1.62E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS25425 b24670621f2b1877e68af0699d4120e3 620 Pfam PF02446 4-alpha-glucanotransferase 122 594 4.5E-107 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CNX65_RS25425 b24670621f2b1877e68af0699d4120e3 620 TIGRFAM TIGR00217 malQ: 4-alpha-glucanotransferase 104 597 2.9E-86 T 28-03-2018 IPR003385 Glycoside hydrolase, family 77 GO:0004134|GO:0005975 KEGG: 00500+2.4.1.25|MetaCyc: PWY-5941|MetaCyc: PWY-6724|MetaCyc: PWY-6737|MetaCyc: PWY-7238 CNX65_RS25425 b24670621f2b1877e68af0699d4120e3 620 SUPERFAMILY SSF51445 116 610 1.24E-128 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS25425 b24670621f2b1877e68af0699d4120e3 620 Gene3D G3DSA:3.20.20.80 113 616 1.6E-149 T 28-03-2018 CNX65_RS18520 bb3982c02225754df8e843cce370689c 471 Pfam PF00144 Beta-lactamase 38 337 1.1E-58 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS18520 bb3982c02225754df8e843cce370689c 471 Gene3D G3DSA:3.40.710.10 12 356 6.2E-73 T 28-03-2018 CNX65_RS18520 bb3982c02225754df8e843cce370689c 471 SUPERFAMILY SSF56601 31 337 5.14E-73 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS02070 d965c0058519fe8f815c9138d5eafdf8 426 Gene3D G3DSA:3.40.190.10 36 215 1.0E-37 T 28-03-2018 CNX65_RS02070 d965c0058519fe8f815c9138d5eafdf8 426 Gene3D G3DSA:3.40.190.10 216 382 1.5E-10 T 28-03-2018 CNX65_RS02070 d965c0058519fe8f815c9138d5eafdf8 426 SUPERFAMILY SSF53850 19 424 6.62E-77 T 28-03-2018 CNX65_RS02070 d965c0058519fe8f815c9138d5eafdf8 426 Pfam PF01547 Bacterial extracellular solute-binding protein 49 341 3.0E-48 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS17045 6acf94b5434b2277648716feb7536024 459 SUPERFAMILY SSF52777 17 208 9.45E-19 T 28-03-2018 CNX65_RS17045 6acf94b5434b2277648716feb7536024 459 Pfam PF00668 Condensation domain 16 341 4.3E-22 T 28-03-2018 IPR001242 Condensation domain CNX65_RS17045 6acf94b5434b2277648716feb7536024 459 Gene3D G3DSA:3.30.559.10 8 211 2.8E-17 T 28-03-2018 CNX65_RS17045 6acf94b5434b2277648716feb7536024 459 SUPERFAMILY SSF52777 197 436 4.34E-28 T 28-03-2018 CNX65_RS24100 701b6809ce134a2b2623a75bd36fd544 140 Pfam PF00583 Acetyltransferase (GNAT) family 24 121 2.1E-16 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS24100 701b6809ce134a2b2623a75bd36fd544 140 SUPERFAMILY SSF55729 3 127 1.18E-23 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS24100 701b6809ce134a2b2623a75bd36fd544 140 Gene3D G3DSA:3.40.630.30 1 137 3.0E-24 T 28-03-2018 CNX65_RS31660 4e6ec9b651278ce7b71013af0b0197a2 382 SUPERFAMILY SSF53822 87 295 6.91E-6 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS31660 4e6ec9b651278ce7b71013af0b0197a2 382 Gene3D G3DSA:3.40.50.2300 190 380 3.3E-40 T 28-03-2018 CNX65_RS31660 4e6ec9b651278ce7b71013af0b0197a2 382 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 78 349 4.3E-53 T 28-03-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 CNX65_RS31660 4e6ec9b651278ce7b71013af0b0197a2 382 Gene3D G3DSA:3.40.50.2300 69 189 4.8E-33 T 28-03-2018 CNX65_RS17920 5d10b1b2233b9e5a6c3b51f06e85af48 344 SMART SM00458 216 344 4.8E-15 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS17920 5d10b1b2233b9e5a6c3b51f06e85af48 344 Gene3D G3DSA:3.40.50.1110 9 213 8.5E-28 T 28-03-2018 CNX65_RS17920 5d10b1b2233b9e5a6c3b51f06e85af48 344 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 14 196 3.7E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS17920 5d10b1b2233b9e5a6c3b51f06e85af48 344 SUPERFAMILY SSF52266 4 204 7.47E-32 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS17920 5d10b1b2233b9e5a6c3b51f06e85af48 344 Gene3D G3DSA:2.80.10.50 214 343 9.3E-27 T 28-03-2018 CNX65_RS17920 5d10b1b2233b9e5a6c3b51f06e85af48 344 Pfam PF00652 Ricin-type beta-trefoil lectin domain 218 341 5.9E-20 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS17920 5d10b1b2233b9e5a6c3b51f06e85af48 344 SUPERFAMILY SSF50370 217 342 9.05E-27 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS34075 4cf55a11d459768beb95d72e69cbf58e 339 SUPERFAMILY SSF53383 7 335 1.27E-91 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS34075 4cf55a11d459768beb95d72e69cbf58e 339 PIRSF PIRSF017617 1 339 1.5E-105 T 28-03-2018 IPR023603 Threonine aldolase CNX65_RS34075 4cf55a11d459768beb95d72e69cbf58e 339 Gene3D G3DSA:3.40.640.10 2 254 8.8E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS34075 4cf55a11d459768beb95d72e69cbf58e 339 Pfam PF01212 Beta-eliminating lyase 8 291 2.0E-73 T 28-03-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 CNX65_RS34075 4cf55a11d459768beb95d72e69cbf58e 339 Gene3D G3DSA:3.90.1150.10 255 339 1.0E-14 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS06195 ee3a44091392c48122980277e8998505 244 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 17 239 2.3E-37 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS06195 ee3a44091392c48122980277e8998505 244 Gene3D G3DSA:2.40.240.20 1 70 3.0E-22 T 28-03-2018 CNX65_RS06195 ee3a44091392c48122980277e8998505 244 SUPERFAMILY SSF88697 5 69 4.31E-12 T 28-03-2018 IPR015947 PUA-like domain CNX65_RS06195 ee3a44091392c48122980277e8998505 244 Pfam PF04452 RNA methyltransferase 19 236 1.1E-59 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS06195 ee3a44091392c48122980277e8998505 244 Gene3D G3DSA:3.40.1280.10 72 244 3.4E-51 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CNX65_RS06195 ee3a44091392c48122980277e8998505 244 SUPERFAMILY SSF75217 72 243 9.42E-43 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CNX65_RS06195 ee3a44091392c48122980277e8998505 244 PIRSF PIRSF015601 3 243 3.0E-47 T 28-03-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 KEGG: 00670+2.1.1.19|MetaCyc: PWY-2201 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 SUPERFAMILY SSF52279 397 636 1.31E-46 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 SUPERFAMILY SSF51445 4 396 1.9E-88 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 Pfam PF14310 Fibronectin type III-like domain 667 736 7.7E-20 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 202 218 8.6E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 273 291 8.6E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 102 118 8.6E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 171 187 8.6E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 PRINTS PR00133 Glycosyl hydrolase family 3 signature 125 144 8.6E-19 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 Gene3D G3DSA:2.60.40.10 634 749 3.5E-28 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 Gene3D G3DSA:3.40.50.1700 384 633 6.2E-66 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 SMART SM01217 667 736 9.5E-28 T 28-03-2018 IPR026891 Fibronectin type III-like domain CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 25 353 1.3E-67 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 Gene3D G3DSA:3.20.20.300 11 376 1.8E-95 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS09110 ea571bce0df040d5c3671ab6d87058e2 771 Pfam PF01915 Glycosyl hydrolase family 3 C-terminal domain 397 633 1.6E-46 T 28-03-2018 IPR002772 Glycoside hydrolase family 3 C-terminal domain GO:0004553|GO:0005975 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 Gene3D G3DSA:1.10.10.60 190 248 4.4E-12 T 28-03-2018 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 SUPERFAMILY SSF46689 246 292 2.42E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 247 288 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 Gene3D G3DSA:1.10.10.60 249 295 2.5E-11 T 28-03-2018 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 Gene3D G3DSA:2.60.120.280 26 178 5.0E-9 T 28-03-2018 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 Pfam PF12852 Cupin 2 178 4.3E-32 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 SMART SM00342 210 292 3.6E-28 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 SUPERFAMILY SSF46689 192 243 2.69E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS26375 a933ba612e0d4a8ef093fd033127e6ab 309 Pfam PF12833 Helix-turn-helix domain 216 292 1.9E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS20810 04b0dcb19b4e6054af088e505582bc10 167 Pfam PF01625 Peptide methionine sulfoxide reductase 8 154 1.2E-58 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CNX65_RS20810 04b0dcb19b4e6054af088e505582bc10 167 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 5 160 35.265 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CNX65_RS20810 04b0dcb19b4e6054af088e505582bc10 167 SUPERFAMILY SSF55068 5 162 6.15E-66 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CNX65_RS20810 04b0dcb19b4e6054af088e505582bc10 167 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 7 154 1.5E-50 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CNX65_RS20810 04b0dcb19b4e6054af088e505582bc10 167 Gene3D G3DSA:3.30.1060.10 4 167 3.5E-66 T 28-03-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 CNX65_RS13260 705462d20e44cbd66f9b6e34c466bf3c 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 70 1.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13260 705462d20e44cbd66f9b6e34c466bf3c 216 Gene3D G3DSA:1.10.357.10 12 205 1.0E-27 T 28-03-2018 CNX65_RS13260 705462d20e44cbd66f9b6e34c466bf3c 216 SUPERFAMILY SSF46689 14 84 2.6E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS13260 705462d20e44cbd66f9b6e34c466bf3c 216 SUPERFAMILY SSF48498 91 199 1.25E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 Pfam PF00990 Diguanylate cyclase, GGDEF domain 385 533 2.7E-37 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 Gene3D G3DSA:1.25.40.10 15 185 5.0E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 Gene3D G3DSA:1.25.40.10 189 383 0.0042 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 SMART SM00267 374 539 2.4E-48 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 Gene3D G3DSA:3.30.70.270 384 547 2.6E-49 T 28-03-2018 CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 SUPERFAMILY SSF48452 95 223 3.57E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 SUPERFAMILY SSF55073 390 538 1.8E-39 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS03260 06e34032be87b31095a096555fbe2766 547 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 382 536 6.4E-39 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS24860 8462266ad90d4a969eefc528c67285aa 684 Gene3D G3DSA:3.40.50.300 164 546 2.8E-28 T 28-03-2018 CNX65_RS24860 8462266ad90d4a969eefc528c67285aa 684 SUPERFAMILY SSF52540 159 237 1.69E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24860 8462266ad90d4a969eefc528c67285aa 684 SUPERFAMILY SSF52540 470 671 1.69E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24860 8462266ad90d4a969eefc528c67285aa 684 SUPERFAMILY SSF52540 317 384 1.69E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24860 8462266ad90d4a969eefc528c67285aa 684 Gene3D G3DSA:3.40.50.300 628 671 2.4E-5 T 28-03-2018 CNX65_RS06280 6c86c155bc74de826498214fc1e19f4b 242 Gene3D G3DSA:1.20.58.370 1 97 0.0011 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CNX65_RS06280 6c86c155bc74de826498214fc1e19f4b 242 Pfam PF09323 Domain of unknown function (DUF1980) 8 118 1.2E-11 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CNX65_RS06280 6c86c155bc74de826498214fc1e19f4b 242 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 22 240 2.9E-52 T 28-03-2018 IPR015402 Protein of unknown function DUF1980 CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 Pfam PF04851 Type III restriction enzyme, res subunit 181 326 7.5E-13 T 28-03-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 Gene3D G3DSA:3.40.50.300 171 355 1.6E-26 T 28-03-2018 CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 Gene3D G3DSA:3.40.50.300 380 515 1.3E-16 T 28-03-2018 CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 353 540 1.7E-44 T 28-03-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 SUPERFAMILY SSF52540 141 343 2.38E-31 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 Pfam PF13625 Helicase conserved C-terminal domain 6 134 1.6E-46 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 SMART SM00487 178 353 1.9E-22 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 SUPERFAMILY SSF52540 393 513 2.13E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 SUPERFAMILY SSF52540 290 360 2.13E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02300 b3fdbf694e2ac63786d1c4736420308a 550 SMART SM00490 423 500 7.4E-9 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS06100 a8950910ddd4b5dcaa2abea4ff57896b 490 PIRSF PIRSF006060 24 487 3.1E-84 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS06100 a8950910ddd4b5dcaa2abea4ff57896b 490 Pfam PF13520 Amino acid permease 35 446 3.6E-56 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS31605 05439b8cc198387d72c8532cce0e08dd 124 Gene3D G3DSA:3.30.1310.10 1 99 1.6E-11 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS12535 001dec6c2dd0c595c4e694e107acfe8f 355 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 67 76 - T 28-03-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 CNX65_RS12535 001dec6c2dd0c595c4e694e107acfe8f 355 Gene3D G3DSA:3.40.630.10 2 355 9.9E-43 T 28-03-2018 CNX65_RS12535 001dec6c2dd0c595c4e694e107acfe8f 355 Pfam PF01546 Peptidase family M20/M25/M40 68 352 7.7E-28 T 28-03-2018 IPR002933 Peptidase M20 GO:0008152|GO:0016787 CNX65_RS12535 001dec6c2dd0c595c4e694e107acfe8f 355 Pfam PF07687 Peptidase dimerisation domain 164 249 6.0E-13 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS12535 001dec6c2dd0c595c4e694e107acfe8f 355 SUPERFAMILY SSF55031 166 249 9.12E-15 T 28-03-2018 IPR011650 Peptidase M20, dimerisation domain CNX65_RS12535 001dec6c2dd0c595c4e694e107acfe8f 355 SUPERFAMILY SSF53187 274 352 4.86E-40 T 28-03-2018 CNX65_RS12535 001dec6c2dd0c595c4e694e107acfe8f 355 SUPERFAMILY SSF53187 3 166 4.86E-40 T 28-03-2018 CNX65_RS15895 9e8962ff75a6e62532b0ac6e46338893 89 ProSitePatterns PS00012 Phosphopantetheine attachment site. 37 52 - T 28-03-2018 IPR006162 Phosphopantetheine attachment site CNX65_RS15895 9e8962ff75a6e62532b0ac6e46338893 89 SUPERFAMILY SSF47336 6 84 2.49E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15895 9e8962ff75a6e62532b0ac6e46338893 89 Gene3D G3DSA:1.10.1200.10 3 87 2.5E-7 T 28-03-2018 CNX65_RS32050 307ebc40485da6a8dd80838c97ecdf73 565 Pfam PF05199 GMC oxidoreductase 463 520 6.0E-15 T 28-03-2018 IPR007867 Glucose-methanol-choline oxidoreductase, C-terminal GO:0016614|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS32050 307ebc40485da6a8dd80838c97ecdf73 565 SUPERFAMILY SSF51905 9 303 2.66E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32050 307ebc40485da6a8dd80838c97ecdf73 565 SUPERFAMILY SSF51905 465 524 2.66E-49 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32050 307ebc40485da6a8dd80838c97ecdf73 565 Gene3D G3DSA:3.50.50.60 8 523 9.6E-62 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32050 307ebc40485da6a8dd80838c97ecdf73 565 Pfam PF00732 GMC oxidoreductase 11 278 3.3E-14 T 28-03-2018 IPR000172 Glucose-methanol-choline oxidoreductase, N-terminal GO:0016614|GO:0050660|GO:0055114 Reactome: R-HSA-6798163 CNX65_RS00080 1ca8c0447920fa319254161d10d5f478 140 Pfam PF10756 Bacterial PH domain 61 139 4.1E-12 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CNX65_RS14180 15444be8c98043629ed49c4e02ea07b7 163 Pfam PF13586 Transposase DDE domain 60 137 5.9E-11 T 28-03-2018 IPR025668 Transposase DDE domain CNX65_RS18070 73581b53d5c9d62b61f1ec49529dcc18 127 SUPERFAMILY SSF54427 28 124 3.58E-8 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS18070 73581b53d5c9d62b61f1ec49529dcc18 127 Gene3D G3DSA:3.10.450.50 14 124 1.7E-10 T 28-03-2018 CNX65_RS28170 4b0af1da1348748864886e0792104ad3 458 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 236 255 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CNX65_RS28170 4b0af1da1348748864886e0792104ad3 458 Gene3D G3DSA:3.90.1150.10 305 450 2.8E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS28170 4b0af1da1348748864886e0792104ad3 458 Gene3D G3DSA:3.40.640.10 61 304 1.3E-44 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS28170 4b0af1da1348748864886e0792104ad3 458 SUPERFAMILY SSF53383 52 429 5.51E-82 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS28170 4b0af1da1348748864886e0792104ad3 458 Pfam PF00266 Aminotransferase class-V 54 421 4.2E-75 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS05315 e2509e0ef712f4dac2f43f0cdbb5704a 424 Pfam PF07690 Major Facilitator Superfamily 16 276 2.3E-22 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS05315 e2509e0ef712f4dac2f43f0cdbb5704a 424 Gene3D G3DSA:1.20.1250.20 216 412 1.8E-19 T 28-03-2018 CNX65_RS05315 e2509e0ef712f4dac2f43f0cdbb5704a 424 SUPERFAMILY SSF103473 7 410 1.83E-55 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS05315 e2509e0ef712f4dac2f43f0cdbb5704a 424 Gene3D G3DSA:1.20.1250.20 2 196 7.2E-23 T 28-03-2018 CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 SUPERFAMILY SSF48008 79 208 1.26E-15 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 SUPERFAMILY SSF46785 5 94 1.87E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 71 4.8E-15 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 Gene3D G3DSA:1.20.120.530 87 212 5.3E-16 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 SMART SM00345 13 71 8.8E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 Gene3D G3DSA:1.10.10.10 4 86 1.2E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 45 61 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 31 45 1.1E-5 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 SMART SM00895 81 204 2.2E-5 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS06990 b23592119f96dbe347d275c7beca2026 212 Pfam PF07729 FCD domain 85 200 4.4E-15 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 SMART SM00422 8 76 4.6E-26 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 Pfam PF09278 MerR, DNA binding 50 115 4.2E-19 T 28-03-2018 IPR015358 Transcription regulator MerR, DNA binding CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 TIGRFAM TIGR01950 SoxR: redox-sensitive transcriptional activator SoxR 8 145 7.3E-62 T 28-03-2018 IPR010211 Redox-sensitive transcriptional activator SoxR GO:0003677|GO:0006355|GO:0006979|GO:0051537 CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 SUPERFAMILY SSF46955 8 128 1.14E-29 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 Pfam PF00376 MerR family regulatory protein 9 45 3.6E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 Gene3D G3DSA:1.10.1660.10 63 139 3.0E-12 T 28-03-2018 CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 Gene3D G3DSA:1.10.1660.10 5 62 9.2E-23 T 28-03-2018 CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 9 20 4.1E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 20 33 4.1E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS28025 27a219b2ca7aed47baf8da72e5e3fcbc 153 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 43 63 4.1E-12 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS03015 5a6c3dfe11369373718881dd942df54d 79 SUPERFAMILY SSF143800 3 78 8.63E-25 T 28-03-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03015 5a6c3dfe11369373718881dd942df54d 79 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 2 68 18.737 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS03015 5a6c3dfe11369373718881dd942df54d 79 TIGRFAM TIGR00009 L28: ribosomal protein bL28 3 59 1.6E-22 T 28-03-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS03015 5a6c3dfe11369373718881dd942df54d 79 Pfam PF00830 Ribosomal L28 family 4 62 5.4E-21 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS03015 5a6c3dfe11369373718881dd942df54d 79 Gene3D G3DSA:2.30.170.40 3 76 7.2E-23 T 28-03-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS11645 1603f4ef8236082fce595af69dd01a65 162 SUPERFAMILY SSF55961 1 152 2.65E-31 T 28-03-2018 CNX65_RS11645 1603f4ef8236082fce595af69dd01a65 162 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 11 151 5.4E-20 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS11645 1603f4ef8236082fce595af69dd01a65 162 Gene3D G3DSA:3.30.530.20 1 162 2.4E-26 T 28-03-2018 IPR023393 START-like domain CNX65_RS22380 4a56d310d58b13c5b053a4c5fe66ff0f 226 SUPERFAMILY SSF54637 89 218 1.0E-14 T 28-03-2018 IPR029069 HotDog domain CNX65_RS22380 4a56d310d58b13c5b053a4c5fe66ff0f 226 Gene3D G3DSA:3.10.129.10 1 225 1.0E-13 T 28-03-2018 CNX65_RS11360 fc287438ccc1debd30d657bec082f96a 355 Gene3D G3DSA:3.30.565.10 235 355 2.6E-21 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11360 fc287438ccc1debd30d657bec082f96a 355 Pfam PF07730 Histidine kinase 159 224 3.1E-19 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS11360 fc287438ccc1debd30d657bec082f96a 355 SUPERFAMILY SSF55874 254 354 4.3E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS28950 e6ca7f1da9564c7e45099c62556d8fd8 476 Gene3D G3DSA:1.10.510.10 73 271 6.6E-47 T 28-03-2018 CNX65_RS28950 e6ca7f1da9564c7e45099c62556d8fd8 476 Gene3D G3DSA:3.30.200.20 1 72 2.5E-22 T 28-03-2018 CNX65_RS28950 e6ca7f1da9564c7e45099c62556d8fd8 476 SUPERFAMILY SSF56112 4 254 3.51E-70 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS28950 e6ca7f1da9564c7e45099c62556d8fd8 476 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 14 37 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS28950 e6ca7f1da9564c7e45099c62556d8fd8 476 Pfam PF00069 Protein kinase domain 8 247 1.3E-47 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS28950 e6ca7f1da9564c7e45099c62556d8fd8 476 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 120 132 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS28950 e6ca7f1da9564c7e45099c62556d8fd8 476 SMART SM00220 8 255 4.2E-57 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS29685 c6c5571e24bb8da3b808c9710ddc871d 99 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 95 2.7E-22 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CNX65_RS29685 c6c5571e24bb8da3b808c9710ddc871d 99 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 21 91 2.4E-15 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CNX65_RS29685 c6c5571e24bb8da3b808c9710ddc871d 99 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 23.119 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CNX65_RS29685 c6c5571e24bb8da3b808c9710ddc871d 99 SUPERFAMILY SSF141000 3 94 6.67E-27 T 28-03-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 CNX65_RS16195 15f14d963343ebbc77f934a56deb573a 441 Gene3D G3DSA:3.50.50.60 2 356 3.0E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS16195 15f14d963343ebbc77f934a56deb573a 441 Pfam PF04820 Tryptophan halogenase 102 358 1.8E-19 T 28-03-2018 IPR006905 Flavin-dependent halogenase CNX65_RS16195 15f14d963343ebbc77f934a56deb573a 441 Pfam PF04820 Tryptophan halogenase 5 76 2.3E-10 T 28-03-2018 IPR006905 Flavin-dependent halogenase CNX65_RS16195 15f14d963343ebbc77f934a56deb573a 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 1.7E-6 T 28-03-2018 CNX65_RS16195 15f14d963343ebbc77f934a56deb573a 441 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 157 172 1.7E-6 T 28-03-2018 CNX65_RS16195 15f14d963343ebbc77f934a56deb573a 441 SUPERFAMILY SSF51905 282 358 4.83E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS16195 15f14d963343ebbc77f934a56deb573a 441 SUPERFAMILY SSF51905 2 178 4.83E-44 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10560 a82902d7370804b57226f3e20119e57b 142 Gene3D G3DSA:3.30.450.30 6 133 3.4E-43 T 28-03-2018 CNX65_RS10560 a82902d7370804b57226f3e20119e57b 142 SUPERFAMILY SSF103196 6 130 3.84E-38 T 28-03-2018 CNX65_RS10560 a82902d7370804b57226f3e20119e57b 142 Pfam PF03259 Roadblock/LC7 domain 11 100 3.3E-25 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS10560 a82902d7370804b57226f3e20119e57b 142 SMART SM00960 11 101 8.2E-33 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS27325 ae291c9308f7ce5a4f143cb39a288dfc 225 SUPERFAMILY SSF56281 25 221 2.23E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS27325 ae291c9308f7ce5a4f143cb39a288dfc 225 Pfam PF00753 Metallo-beta-lactamase superfamily 33 191 2.5E-14 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS27325 ae291c9308f7ce5a4f143cb39a288dfc 225 SMART SM00849 36 204 1.2E-29 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS27325 ae291c9308f7ce5a4f143cb39a288dfc 225 Gene3D G3DSA:3.60.15.10 21 223 1.8E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS13095 f95a61be89614f2d2e0c622800e4db4e 1164 Gene3D G3DSA:1.10.287.1060 89 169 7.2E-9 T 28-03-2018 CNX65_RS13095 f95a61be89614f2d2e0c622800e4db4e 1164 SUPERFAMILY SSF140459 101 223 1.52E-7 T 28-03-2018 CNX65_RS13095 f95a61be89614f2d2e0c622800e4db4e 1164 Pfam PF13930 DNA/RNA non-specific endonuclease 988 1128 2.8E-7 T 28-03-2018 CNX65_RS23890 324715f9fe68d173a4f59d5e5d343f0b 132 Gene3D G3DSA:3.40.1350.10 1 117 7.7E-25 T 28-03-2018 CNX65_RS23890 324715f9fe68d173a4f59d5e5d343f0b 132 SUPERFAMILY SSF52980 3 113 9.38E-24 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CNX65_RS23890 324715f9fe68d173a4f59d5e5d343f0b 132 Pfam PF04471 Restriction endonuclease 1 111 1.7E-29 T 28-03-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 CNX65_RS21720 d2ee9463a8983b89105af7e2719cae60 300 Pfam PF03741 Integral membrane protein TerC family 15 201 5.0E-48 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CNX65_RS33045 824511c8148cdc052cad6928e22a8af0 60 Pfam PF04149 Domain of unknown function (DUF397) 7 59 2.8E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS08715 ef8a74b1bf04dd08d99e3ae146e373ab 419 SUPERFAMILY SSF51445 130 302 6.55E-7 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS08715 ef8a74b1bf04dd08d99e3ae146e373ab 419 Gene3D G3DSA:3.20.20.80 39 311 1.8E-5 T 28-03-2018 CNX65_RS25615 05be586daaf4f9abd312cd162503d165 425 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 232 251 - T 28-03-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site CNX65_RS25615 05be586daaf4f9abd312cd162503d165 425 Gene3D G3DSA:3.40.640.10 40 297 4.2E-58 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS25615 05be586daaf4f9abd312cd162503d165 425 Gene3D G3DSA:3.90.1150.10 298 418 5.7E-41 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS25615 05be586daaf4f9abd312cd162503d165 425 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 13 423 1.5E-169 T 28-03-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CNX65_RS25615 05be586daaf4f9abd312cd162503d165 425 Pfam PF00266 Aminotransferase class-V 31 411 3.4E-134 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS25615 05be586daaf4f9abd312cd162503d165 425 SUPERFAMILY SSF53383 9 418 4.32E-118 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS23205 8a16cee344449605b450a6083a3a8df0 82 SUPERFAMILY SSF47336 7 80 7.2E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS23205 8a16cee344449605b450a6083a3a8df0 82 Gene3D G3DSA:1.10.1200.10 4 82 5.9E-16 T 28-03-2018 CNX65_RS23205 8a16cee344449605b450a6083a3a8df0 82 Pfam PF00550 Phosphopantetheine attachment site 14 76 2.5E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS34690 79ab69fea2850d8bba94d1b55a89e4bd 306 Gene3D G3DSA:3.40.50.300 1 257 1.9E-55 T 28-03-2018 CNX65_RS34690 79ab69fea2850d8bba94d1b55a89e4bd 306 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS34690 79ab69fea2850d8bba94d1b55a89e4bd 306 Pfam PF00005 ABC transporter 18 156 1.4E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS34690 79ab69fea2850d8bba94d1b55a89e4bd 306 SMART SM00382 26 204 4.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS34690 79ab69fea2850d8bba94d1b55a89e4bd 306 SUPERFAMILY SSF52540 2 221 2.57E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26895 6743b505a1b923ad8544f19358c4256e 363 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 7 279 1.6E-47 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS26895 6743b505a1b923ad8544f19358c4256e 363 SUPERFAMILY SSF55931 3 355 2.45E-88 T 28-03-2018 CNX65_RS26895 6743b505a1b923ad8544f19358c4256e 363 Hamap MF_01609 Glutamate--cysteine ligase [gshA]. 1 363 73.354 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS26895 6743b505a1b923ad8544f19358c4256e 363 TIGRFAM TIGR02050 gshA_cyan_rel: carboxylate-amine ligase, YbdK family 6 285 3.0E-78 T 28-03-2018 IPR011793 Putative glutamate--cysteine ligase YbdK GO:0016879 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS09935 8d6991202ceab101435ef01d29b483b8 243 Gene3D G3DSA:3.90.1200.10 70 243 1.4E-13 T 28-03-2018 CNX65_RS09935 8d6991202ceab101435ef01d29b483b8 243 PIRSF PIRSF000706 1 243 3.2E-51 T 28-03-2018 IPR024165 Aminoglycoside 3-phosphotransferase GO:0005524|GO:0016773|GO:0046677 CNX65_RS09935 8d6991202ceab101435ef01d29b483b8 243 Gene3D G3DSA:3.30.200.20 1 67 4.3E-8 T 28-03-2018 CNX65_RS09935 8d6991202ceab101435ef01d29b483b8 243 Pfam PF01636 Phosphotransferase enzyme family 16 230 5.8E-24 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS09935 8d6991202ceab101435ef01d29b483b8 243 SUPERFAMILY SSF56112 25 243 1.18E-32 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS33320 dfee925f343cf3b36784e10023d5960d 331 SUPERFAMILY SSF50494 133 311 1.65E-14 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS33320 dfee925f343cf3b36784e10023d5960d 331 Gene3D G3DSA:2.40.10.10 209 314 1.4E-11 T 28-03-2018 CNX65_RS23930 1506127f1484f94f6ea0c777e0e7b57d 361 Gene3D G3DSA:3.40.50.720 2 143 1.7E-33 T 28-03-2018 CNX65_RS23930 1506127f1484f94f6ea0c777e0e7b57d 361 Gene3D G3DSA:3.30.360.10 144 338 2.2E-38 T 28-03-2018 CNX65_RS23930 1506127f1484f94f6ea0c777e0e7b57d 361 SUPERFAMILY SSF55347 131 267 4.91E-27 T 28-03-2018 CNX65_RS23930 1506127f1484f94f6ea0c777e0e7b57d 361 SUPERFAMILY SSF51735 5 156 7.05E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23930 1506127f1484f94f6ea0c777e0e7b57d 361 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 118 1.8E-20 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS23930 1506127f1484f94f6ea0c777e0e7b57d 361 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 134 244 1.9E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS16205 de03095be10dbdc8eac10253ac5b0010 90 Pfam PF00550 Phosphopantetheine attachment site 12 80 1.7E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16205 de03095be10dbdc8eac10253ac5b0010 90 SUPERFAMILY SSF47336 15 86 2.09E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16205 de03095be10dbdc8eac10253ac5b0010 90 Gene3D G3DSA:1.10.1200.10 1 88 3.1E-12 T 28-03-2018 CNX65_RS12545 7b65d1557fe56eca9acf4758f16e8a70 197 Gene3D G3DSA:2.70.50.50 12 197 1.5E-46 T 28-03-2018 CNX65_RS12545 7b65d1557fe56eca9acf4758f16e8a70 197 SUPERFAMILY SSF81296 12 196 2.94E-30 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS12545 7b65d1557fe56eca9acf4758f16e8a70 197 Pfam PF03067 Lytic polysaccharide mono-oxygenase, cellulose-degrading 12 194 7.8E-32 T 28-03-2018 IPR004302 Cellulose/chitin-binding protein, N-terminal CNX65_RS14480 69f0da354135d9f5c964ab01dced233b 134 Pfam PF03330 Lytic transglycolase 33 129 1.7E-12 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CNX65_RS14480 69f0da354135d9f5c964ab01dced233b 134 Gene3D G3DSA:2.40.40.10 31 134 7.8E-25 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CNX65_RS14480 69f0da354135d9f5c964ab01dced233b 134 SUPERFAMILY SSF50685 21 133 2.89E-23 T 28-03-2018 IPR009009 RlpA-like protein, double-psi beta-barrel domain CNX65_RS02465 d1b3e3c7d5527d3e9bf4a48da90a9ba5 259 Gene3D G3DSA:2.140.10.10 14 251 1.5E-11 T 28-03-2018 CNX65_RS02465 d1b3e3c7d5527d3e9bf4a48da90a9ba5 259 SUPERFAMILY SSF50969 35 247 1.18E-14 T 28-03-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like CNX65_RS02465 d1b3e3c7d5527d3e9bf4a48da90a9ba5 259 Pfam PF05096 Glutamine cyclotransferase 28 256 1.6E-95 T 28-03-2018 IPR007788 Glutaminyl-peptide cyclotransferase GO:0016603|GO:0017186 CNX65_RS29325 b49916c3328468dbdd23c79a78f22ad5 238 Pfam PF14428 SCP1.201-like deaminase 109 221 1.3E-26 T 28-03-2018 IPR032724 Deaminase, SCP1.201-like CNX65_RS18085 b86a0da8991ca9276355bc55857aa2a4 168 Gene3D G3DSA:1.10.10.10 73 168 1.4E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18085 b86a0da8991ca9276355bc55857aa2a4 168 SUPERFAMILY SSF46894 101 168 4.42E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS18085 b86a0da8991ca9276355bc55857aa2a4 168 SMART SM00421 105 162 5.3E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18085 b86a0da8991ca9276355bc55857aa2a4 168 Pfam PF00196 Bacterial regulatory proteins, luxR family 107 162 6.3E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18085 b86a0da8991ca9276355bc55857aa2a4 168 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 108 122 3.7E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18085 b86a0da8991ca9276355bc55857aa2a4 168 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 150 3.7E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18085 b86a0da8991ca9276355bc55857aa2a4 168 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 122 138 3.7E-6 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS04375 752749fa313665af840ea0762e3c91d6 960 Pfam PF12846 AAA-like domain 622 825 4.9E-20 T 28-03-2018 CNX65_RS04375 752749fa313665af840ea0762e3c91d6 960 Gene3D G3DSA:3.40.50.300 495 849 3.8E-8 T 28-03-2018 CNX65_RS04375 752749fa313665af840ea0762e3c91d6 960 SUPERFAMILY SSF52540 459 575 2.87E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04375 752749fa313665af840ea0762e3c91d6 960 SUPERFAMILY SSF52540 604 822 2.87E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26710 6547dd1c953fee214fe19dea5316a9be 99 Pfam PF02467 Transcription factor WhiB 17 87 3.6E-24 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS26710 6547dd1c953fee214fe19dea5316a9be 99 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 95 19.338 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 58 1.7E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 6.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 Pfam PF13305 WHG domain 95 170 1.2E-13 T 28-03-2018 IPR025996 WHG domain CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 Gene3D G3DSA:1.10.357.10 88 195 3.8E-10 T 28-03-2018 CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 SUPERFAMILY SSF46689 9 79 2.29E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 SUPERFAMILY SSF48498 91 177 1.5E-15 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 Gene3D G3DSA:1.10.10.60 1 44 5.8E-15 T 28-03-2018 CNX65_RS03870 1262f06ea586e508955fe2029a6ae45a 197 Gene3D G3DSA:1.10.260.40 45 87 1.5E-8 T 28-03-2018 CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 ProSitePatterns PS01117 MarR-type HTH domain signature. 88 122 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 Gene3D G3DSA:1.10.10.10 23 167 3.9E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 90 105 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 138 158 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 PRINTS PR00598 Bacterial regulatory protein MarR family signature 109 125 1.1E-8 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 SUPERFAMILY SSF46785 27 162 1.53E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 Pfam PF01047 MarR family 62 113 1.2E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS29930 96f585418902de1ec9d27b467fd79a97 167 SMART SM00347 47 148 1.5E-20 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS33700 ce426ca178b1afe49168f5eaba570a67 220 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 4 211 2.8E-53 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CNX65_RS33700 ce426ca178b1afe49168f5eaba570a67 220 SUPERFAMILY SSF109755 2 213 4.5E-55 T 28-03-2018 CNX65_RS33700 ce426ca178b1afe49168f5eaba570a67 220 PIRSF PIRSF003107 1 215 1.5E-53 T 28-03-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 CNX65_RS33700 ce426ca178b1afe49168f5eaba570a67 220 Pfam PF01895 PhoU domain 122 204 1.2E-10 T 28-03-2018 IPR026022 PhoU domain CNX65_RS33700 ce426ca178b1afe49168f5eaba570a67 220 Pfam PF01895 PhoU domain 16 103 1.8E-15 T 28-03-2018 IPR026022 PhoU domain CNX65_RS33700 ce426ca178b1afe49168f5eaba570a67 220 Gene3D G3DSA:1.20.58.220 1 112 4.9E-19 T 28-03-2018 CNX65_RS33700 ce426ca178b1afe49168f5eaba570a67 220 Gene3D G3DSA:1.20.58.220 113 215 2.5E-15 T 28-03-2018 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 SUPERFAMILY SSF51604 140 421 1.56E-122 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 Gene3D G3DSA:3.20.20.120 128 425 1.3E-99 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 Hamap MF_00318 Enolase [eno]. 2 411 43.394 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 PRINTS PR00148 Enolase signature 311 322 5.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 PRINTS PR00148 Enolase signature 363 380 5.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 PRINTS PR00148 Enolase signature 37 51 5.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 PRINTS PR00148 Enolase signature 161 174 5.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 PRINTS PR00148 Enolase signature 107 123 5.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 PRINTS PR00148 Enolase signature 334 348 5.4E-45 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 423 1.7E-200 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 Gene3D G3DSA:3.30.390.10 3 127 4.6E-49 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 Pfam PF00113 Enolase, C-terminal TIM barrel domain 140 422 3.6E-126 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 SMART SM01192 139 425 1.4E-209 T 28-03-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 SMART SM01193 4 134 6.5E-86 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 SUPERFAMILY SSF54826 4 137 1.43E-52 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 ProSitePatterns PS00164 Enolase signature. 334 347 - T 28-03-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 Pfam PF03952 Enolase, N-terminal domain 4 134 4.1E-56 T 28-03-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS13900 a8db5ec266e5b005a8d6bdf94738a726 426 PIRSF PIRSF001400 1 424 1.5E-183 T 28-03-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS17030 c171cf0be6a98fe18f8cde2f56f3ee7a 261 Pfam PF00975 Thioesterase domain 27 248 2.1E-43 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS17030 c171cf0be6a98fe18f8cde2f56f3ee7a 261 Gene3D G3DSA:3.40.50.1820 9 255 5.0E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17030 c171cf0be6a98fe18f8cde2f56f3ee7a 261 SUPERFAMILY SSF53474 11 252 1.8E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS33420 c328eaf34ea90a384b5fa01b9fffb268 155 Pfam PF11706 CGNR zinc finger 106 149 2.3E-16 T 28-03-2018 IPR021005 Zinc finger, CGNR CNX65_RS33420 c328eaf34ea90a384b5fa01b9fffb268 155 Gene3D G3DSA:1.10.3300.10 1 151 2.8E-26 T 28-03-2018 IPR023286 ABATE domain CNX65_RS33420 c328eaf34ea90a384b5fa01b9fffb268 155 SUPERFAMILY SSF160904 2 148 7.98E-31 T 28-03-2018 CNX65_RS31285 e5fd14f6e2dc723e9f7d5aad577dc7b6 127 SUPERFAMILY SSF46785 5 78 4.28E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31285 e5fd14f6e2dc723e9f7d5aad577dc7b6 127 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 1.1E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS31285 e5fd14f6e2dc723e9f7d5aad577dc7b6 127 SMART SM00345 17 76 4.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS31285 e5fd14f6e2dc723e9f7d5aad577dc7b6 127 Gene3D G3DSA:1.10.10.10 1 78 4.3E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 Pfam PF12802 MarR family 18 56 5.3E-7 T 28-03-2018 CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 ProSitePatterns PS01125 ROK family signature. 210 237 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 Gene3D G3DSA:3.30.420.40 268 348 6.1E-9 T 28-03-2018 CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 Gene3D G3DSA:3.30.420.40 217 267 4.0E-19 T 28-03-2018 CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 SUPERFAMILY SSF46785 7 68 2.73E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 SUPERFAMILY SSF53067 79 344 2.05E-41 T 28-03-2018 CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 Gene3D G3DSA:3.30.420.40 75 216 1.5E-39 T 28-03-2018 CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 Pfam PF00480 ROK family 87 260 1.5E-31 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS30540 0bce5ae2af24cc65bae10b930093a247 350 Gene3D G3DSA:1.10.10.10 12 73 6.7E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30795 8cb9bab8c2f05b0b60eac58bc634fa05 194 Gene3D G3DSA:2.60.40.1240 71 168 0.0013 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CNX65_RS30795 8cb9bab8c2f05b0b60eac58bc634fa05 194 Pfam PF14016 Protein of unknown function (DUF4232) 73 177 5.1E-21 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CNX65_RS32215 a3c5118698edf5f2afd012626123c2cc 201 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 72 201 32.597 T 28-03-2018 IPR023035 Ribosomal protein S9, bacterial/plastid CNX65_RS32215 a3c5118698edf5f2afd012626123c2cc 201 Gene3D G3DSA:3.30.230.10 75 201 3.7E-49 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS32215 a3c5118698edf5f2afd012626123c2cc 201 Pfam PF00380 Ribosomal protein S9/S16 81 201 2.3E-44 T 28-03-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32215 a3c5118698edf5f2afd012626123c2cc 201 ProSitePatterns PS00360 Ribosomal protein S9 signature. 140 158 - T 28-03-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 CNX65_RS32215 a3c5118698edf5f2afd012626123c2cc 201 SUPERFAMILY SSF54211 77 201 6.83E-45 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS27045 98eda7733b6ab9999337ee6acbae0c18 194 Pfam PF08044 Domain of unknown function (DUF1707) 7 59 1.8E-19 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CNX65_RS27045 98eda7733b6ab9999337ee6acbae0c18 194 Pfam PF05154 TM2 domain 129 177 1.2E-17 T 28-03-2018 IPR007829 TM2 domain CNX65_RS10650 0ecc6550c950d7d2abdd9f5ef4ca1f41 182 Pfam PF01230 HIT domain 57 146 1.5E-14 T 28-03-2018 IPR001310 Histidine triad (HIT) protein CNX65_RS10650 0ecc6550c950d7d2abdd9f5ef4ca1f41 182 SUPERFAMILY SSF54197 18 176 2.17E-42 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS10650 0ecc6550c950d7d2abdd9f5ef4ca1f41 182 Gene3D G3DSA:3.30.428.10 5 182 9.8E-42 T 28-03-2018 IPR011146 HIT-like domain GO:0003824 CNX65_RS11620 ae6a5d450bab7dd3f3bbf58e847d7394 374 Pfam PF00296 Luciferase-like monooxygenase 1 294 4.6E-57 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS11620 ae6a5d450bab7dd3f3bbf58e847d7394 374 SUPERFAMILY SSF51679 1 331 1.83E-68 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS11620 ae6a5d450bab7dd3f3bbf58e847d7394 374 Gene3D G3DSA:3.20.20.30 1 347 1.2E-65 T 28-03-2018 CNX65_RS11620 ae6a5d450bab7dd3f3bbf58e847d7394 374 TIGRFAM TIGR04036 LLM_CE1758_fam: putative luciferase-like monooxygenase, FMN-dependent, CE1758 family 1 353 3.4E-215 T 28-03-2018 IPR023934 Luciferase-like monooxygenase, FMN-dependent, putative CNX65_RS04540 0962bd0990c8d8237b33f5bfa8e7277d 242 ProDom PD037701 MEMBRANE INTEGRAL TRANSMEMBRANE RV2219/MT2276 NARROWLY PROBABLE PRECURSOR SIGNAL MLCB22.21 27 227 3.0E-63 T 28-03-2018 CNX65_RS04540 0962bd0990c8d8237b33f5bfa8e7277d 242 Pfam PF13829 Domain of unknown function (DUF4191) 20 233 7.3E-86 T 28-03-2018 IPR025445 Protein of unknown function DUF4191 CNX65_RS34970 ea6d7772e06b18b9e03eff31272727c3 174 ProSitePatterns PS00893 Nudix box signature. 63 84 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS34970 ea6d7772e06b18b9e03eff31272727c3 174 Pfam PF00293 NUDIX domain 41 155 1.3E-21 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS34970 ea6d7772e06b18b9e03eff31272727c3 174 SUPERFAMILY SSF55811 31 161 1.49E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS34970 ea6d7772e06b18b9e03eff31272727c3 174 PRINTS PR00502 NUDIX hydrolase family signature 58 72 1.9E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS34970 ea6d7772e06b18b9e03eff31272727c3 174 PRINTS PR00502 NUDIX hydrolase family signature 72 87 1.9E-8 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS34970 ea6d7772e06b18b9e03eff31272727c3 174 Gene3D G3DSA:3.90.79.10 27 164 2.3E-31 T 28-03-2018 CNX65_RS08345 14abd654152b11a8c9d97807d0f7b9e0 407 Gene3D G3DSA:3.40.50.2300 218 371 1.3E-22 T 28-03-2018 CNX65_RS08345 14abd654152b11a8c9d97807d0f7b9e0 407 TIGRFAM TIGR03407 urea_ABC_UrtA: urea ABC transporter, urea binding protein 40 396 8.2E-173 T 28-03-2018 IPR017777 Urea ABC transporter, substrate-binding protein UrtA-like CNX65_RS08345 14abd654152b11a8c9d97807d0f7b9e0 407 Gene3D G3DSA:3.40.50.2300 35 217 2.5E-31 T 28-03-2018 CNX65_RS08345 14abd654152b11a8c9d97807d0f7b9e0 407 Pfam PF13433 Periplasmic binding protein domain 40 398 9.9E-154 T 28-03-2018 CNX65_RS08345 14abd654152b11a8c9d97807d0f7b9e0 407 SUPERFAMILY SSF53822 39 400 1.24E-103 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 184 195 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 Gene3D G3DSA:2.60.120.380 755 873 0.51 T 28-03-2018 CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 SUPERFAMILY SSF52743 166 199 1.36E-54 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 SUPERFAMILY SSF52743 337 618 1.36E-54 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 Gene3D G3DSA:3.40.50.200 145 628 5.9E-70 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 Gene3D G3DSA:2.60.120.380 913 1010 1.0E-6 T 28-03-2018 CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 555 565 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 PRINTS PR00723 Subtilisin serine protease family (S8) signature 179 198 7.3E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 PRINTS PR00723 Subtilisin serine protease family (S8) signature 359 372 7.3E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 PRINTS PR00723 Subtilisin serine protease family (S8) signature 554 570 7.3E-17 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS30585 4f06c0da9dd80d9e42b18352d1146e56 1079 Pfam PF00082 Subtilase family 179 610 1.5E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS31645 8c9fd864c75debd3243e9ba8ff7bbb3d 416 Pfam PF02653 Branched-chain amino acid transport system / permease component 56 330 4.7E-33 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS31645 8c9fd864c75debd3243e9ba8ff7bbb3d 416 Gene3D G3DSA:1.10.3470.10 43 357 3.5E-48 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS28675 81c91320119948d61f10c3e9d986fbdb 229 Gene3D G3DSA:1.10.150.240 20 72 7.0E-6 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CNX65_RS28675 81c91320119948d61f10c3e9d986fbdb 229 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 183 5.3E-18 T 28-03-2018 CNX65_RS28675 81c91320119948d61f10c3e9d986fbdb 229 SUPERFAMILY SSF56784 3 222 4.06E-30 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS28675 81c91320119948d61f10c3e9d986fbdb 229 Gene3D G3DSA:3.40.50.1000 73 228 2.1E-20 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS18200 2727283be55de11f2115ab1beba4740c 155 SUPERFAMILY SSF54534 67 139 3.66E-9 T 28-03-2018 CNX65_RS18200 2727283be55de11f2115ab1beba4740c 155 Gene3D G3DSA:3.10.50.30 62 150 2.4E-15 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CNX65_RS18200 2727283be55de11f2115ab1beba4740c 155 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 68 140 3.3E-10 T 28-03-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 CNX65_RS32550 e67e992e2efe105c41559a2d6079484a 260 Pfam PF02405 Permease MlaE 39 249 2.1E-68 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 ProSitePatterns PS00653 Glycosyl hydrolases family 1 N-terminal signature. 10 24 - T 28-03-2018 IPR033132 Glycosyl hydrolases family 1, N-terminal conserved site CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 Gene3D G3DSA:3.20.20.80 4 463 7.0E-173 T 28-03-2018 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 SUPERFAMILY SSF51445 5 465 1.96E-168 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 TIGRFAM TIGR03356 BGL: beta-galactosidase 6 454 4.1E-185 T 28-03-2018 IPR017736 Glycoside hydrolase, family 1, beta-glucosidase GO:0008422|GO:0030245 KEGG: 00460+3.2.1.21|KEGG: 00500+3.2.1.21|KEGG: 00940+3.2.1.21|MetaCyc: PWY-3121|MetaCyc: PWY-5176|MetaCyc: PWY-6002|MetaCyc: PWY-6788|MetaCyc: PWY-7091|MetaCyc: PWY-7092 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 432 444 3.4E-22 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 366 374 3.4E-22 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 408 425 3.4E-22 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 287 301 3.4E-22 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 PRINTS PR00131 Glycosyl hydrolase family 1 signature 387 398 3.4E-22 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 ProSitePatterns PS00572 Glycosyl hydrolases family 1 active site. 366 374 - T 28-03-2018 IPR018120 Glycoside hydrolase family 1, active site CNX65_RS08910 32187f9753b0d1c3dd8b26a63df59617 472 Pfam PF00232 Glycosyl hydrolase family 1 5 461 2.2E-169 T 28-03-2018 IPR001360 Glycoside hydrolase family 1 GO:0004553|GO:0005975 CNX65_RS18570 848e552fcc0e612471b7b383a26f4a97 521 Pfam PF00128 Alpha amylase, catalytic domain 33 385 6.4E-68 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS18570 848e552fcc0e612471b7b383a26f4a97 521 Gene3D G3DSA:3.20.20.80 6 433 1.2E-99 T 28-03-2018 CNX65_RS18570 848e552fcc0e612471b7b383a26f4a97 521 Gene3D G3DSA:2.60.40.1180 438 515 3.0E-15 T 28-03-2018 CNX65_RS18570 848e552fcc0e612471b7b383a26f4a97 521 SUPERFAMILY SSF51445 356 433 5.47E-109 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS18570 848e552fcc0e612471b7b383a26f4a97 521 SUPERFAMILY SSF51445 9 328 5.47E-109 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS18570 848e552fcc0e612471b7b383a26f4a97 521 SUPERFAMILY SSF51011 442 514 4.32E-7 T 28-03-2018 CNX65_RS18570 848e552fcc0e612471b7b383a26f4a97 521 SMART SM00642 18 426 1.0E-90 T 28-03-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 CNX65_RS21300 13c587e6c58ad73d2698e03fa3497e3e 454 SUPERFAMILY SSF51735 300 431 1.87E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21300 13c587e6c58ad73d2698e03fa3497e3e 454 SUPERFAMILY SSF51735 128 227 1.87E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21300 13c587e6c58ad73d2698e03fa3497e3e 454 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 296 399 3.4E-7 T 28-03-2018 CNX65_RS21300 13c587e6c58ad73d2698e03fa3497e3e 454 Gene3D G3DSA:3.40.50.720 82 446 2.5E-53 T 28-03-2018 CNX65_RS21300 13c587e6c58ad73d2698e03fa3497e3e 454 Pfam PF00106 short chain dehydrogenase 134 225 1.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 SUPERFAMILY SSF51735 139 303 1.53E-43 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 Gene3D G3DSA:3.90.180.10 1 163 2.4E-60 T 28-03-2018 CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 Pfam PF00107 Zinc-binding dehydrogenase 175 298 4.4E-30 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 134 1.2E-31 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 Gene3D G3DSA:3.40.50.720 164 306 2.5E-26 T 28-03-2018 CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 SMART SM00829 10 334 3.1E-6 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS09510 c019d4878587a1c637c33f262ed16e5e 336 SUPERFAMILY SSF50129 1 180 7.0E-55 T 28-03-2018 IPR011032 GroES-like CNX65_RS17520 31fb298ab33f7f2ad4c01ee405dec9b5 639 Gene3D G3DSA:2.130.10.120 63 348 4.4E-14 T 28-03-2018 CNX65_RS17520 31fb298ab33f7f2ad4c01ee405dec9b5 639 Gene3D G3DSA:3.40.50.1820 349 628 1.7E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17520 31fb298ab33f7f2ad4c01ee405dec9b5 639 Pfam PF00326 Prolyl oligopeptidase family 417 626 7.1E-41 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS17520 31fb298ab33f7f2ad4c01ee405dec9b5 639 SUPERFAMILY SSF53474 365 626 2.08E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17520 31fb298ab33f7f2ad4c01ee405dec9b5 639 SUPERFAMILY SSF69322 65 322 6.8E-14 T 28-03-2018 CNX65_RS13090 5a4b840146c55173d92fb304e8383948 206 Pfam PF04542 Sigma-70 region 2 44 112 4.7E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13090 5a4b840146c55173d92fb304e8383948 206 SUPERFAMILY SSF88946 20 121 1.33E-14 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13090 5a4b840146c55173d92fb304e8383948 206 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 40 198 4.4E-20 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13090 5a4b840146c55173d92fb304e8383948 206 Gene3D G3DSA:1.10.1740.10 17 124 2.4E-15 T 28-03-2018 CNX65_RS13090 5a4b840146c55173d92fb304e8383948 206 Pfam PF08281 Sigma-70, region 4 144 196 1.9E-8 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13090 5a4b840146c55173d92fb304e8383948 206 SUPERFAMILY SSF88659 139 200 4.36E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS13090 5a4b840146c55173d92fb304e8383948 206 Gene3D G3DSA:1.10.10.10 125 205 3.1E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08795 ce26e34f9a4e93be0fb76be932c399d5 251 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 28-03-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824|GO:0008152 CNX65_RS08795 ce26e34f9a4e93be0fb76be932c399d5 251 Gene3D G3DSA:1.10.12.10 213 251 8.7E-12 T 28-03-2018 IPR014748 Crontonase, C-terminal CNX65_RS08795 ce26e34f9a4e93be0fb76be932c399d5 251 Gene3D G3DSA:3.90.226.10 2 212 1.8E-56 T 28-03-2018 CNX65_RS08795 ce26e34f9a4e93be0fb76be932c399d5 251 SUPERFAMILY SSF52096 3 251 1.19E-71 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS08795 ce26e34f9a4e93be0fb76be932c399d5 251 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 251 1.4E-44 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS07875 4f6f1ef5173e00f077071dbd37e74d08 234 PIRSF PIRSF000709 9 188 2.3E-18 T 28-03-2018 CNX65_RS07875 4f6f1ef5173e00f077071dbd37e74d08 234 SUPERFAMILY SSF53254 9 226 5.14E-39 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS07875 4f6f1ef5173e00f077071dbd37e74d08 234 Gene3D G3DSA:3.40.50.1240 7 228 2.1E-42 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS07875 4f6f1ef5173e00f077071dbd37e74d08 234 SMART SM00855 9 176 2.0E-5 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS07875 4f6f1ef5173e00f077071dbd37e74d08 234 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 9 215 6.3E-30 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS18415 d10ef18387f60bb60eb161171fae5c12 244 Pfam PF13649 Methyltransferase domain 43 136 1.8E-14 T 28-03-2018 CNX65_RS18415 d10ef18387f60bb60eb161171fae5c12 244 SUPERFAMILY SSF53335 13 243 1.1E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS18415 d10ef18387f60bb60eb161171fae5c12 244 Gene3D G3DSA:3.40.50.150 2 228 2.1E-31 T 28-03-2018 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 2.0E-7 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 Pfam PF13411 MerR HTH family regulatory protein 2 66 6.8E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 Gene3D G3DSA:1.10.1660.10 1 54 8.1E-18 T 28-03-2018 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 SMART SM00422 1 69 9.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 Gene3D G3DSA:1.10.1660.10 55 122 3.4E-6 T 28-03-2018 CNX65_RS14335 7017b02c4151e7e475d1bb82e1a1e090 125 SUPERFAMILY SSF46955 2 110 1.65E-22 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS15990 2f64ef176a49f77c4887b5e1aafe6a9c 246 SUPERFAMILY SSF51569 23 229 1.9E-34 T 28-03-2018 CNX65_RS15990 2f64ef176a49f77c4887b5e1aafe6a9c 246 Pfam PF01791 DeoC/LacD family aldolase 23 210 2.3E-25 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CNX65_RS15990 2f64ef176a49f77c4887b5e1aafe6a9c 246 Gene3D G3DSA:3.20.20.70 3 238 1.9E-38 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS15990 2f64ef176a49f77c4887b5e1aafe6a9c 246 SMART SM01133 9 214 2.6E-9 T 28-03-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 CNX65_RS04100 49995176418b4ce124c16f0f04582ee8 344 SUPERFAMILY SSF53474 46 336 1.89E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04100 49995176418b4ce124c16f0f04582ee8 344 Pfam PF00561 alpha/beta hydrolase fold 78 327 6.5E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04100 49995176418b4ce124c16f0f04582ee8 344 Gene3D G3DSA:3.40.50.1820 5 343 2.2E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04100 49995176418b4ce124c16f0f04582ee8 344 PRINTS PR00111 Alpha/beta hydrolase fold signature 100 115 5.2E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04100 49995176418b4ce124c16f0f04582ee8 344 PRINTS PR00111 Alpha/beta hydrolase fold signature 144 157 5.2E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04100 49995176418b4ce124c16f0f04582ee8 344 PRINTS PR00111 Alpha/beta hydrolase fold signature 158 171 5.2E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Gene3D G3DSA:1.10.20.10 346 472 1.9E-5 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 PRINTS PR00364 Disease resistance protein signature 358 372 1.2E-9 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 PRINTS PR00364 Disease resistance protein signature 283 298 1.2E-9 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 PRINTS PR00364 Disease resistance protein signature 443 457 1.2E-9 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SUPERFAMILY SSF48452 92 257 2.87E-26 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SUPERFAMILY SSF52540 256 469 7.76E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Pfam PF13424 Tetratricopeptide repeat 895 966 2.5E-7 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Pfam PF13424 Tetratricopeptide repeat 775 845 2.3E-7 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SMART SM00862 15 88 5.0E-12 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Pfam PF03704 Bacterial transcriptional activator domain 95 237 1.0E-31 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Gene3D G3DSA:3.40.50.300 277 310 0.0014 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SUPERFAMILY SSF48452 839 969 2.53E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SMART SM01043 95 237 6.0E-40 T 28-03-2018 IPR005158 Bacterial transcriptional activator domain CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SUPERFAMILY SSF48452 695 850 2.66E-18 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Pfam PF00931 NB-ARC domain 281 461 4.0E-9 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SMART SM00028 695 728 70.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SMART SM00028 815 848 490.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SMART SM00028 935 968 43.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SMART SM00028 735 768 300.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SMART SM00028 775 808 3.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Pfam PF00486 Transcriptional regulatory protein, C terminal 21 76 9.1E-10 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Gene3D G3DSA:1.10.150.200 675 741 0.0067 T 28-03-2018 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Gene3D G3DSA:1.25.40.10 92 255 1.1E-20 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Gene3D G3DSA:1.25.40.10 742 832 1.4E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Gene3D G3DSA:1.10.10.10 1 91 5.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 Gene3D G3DSA:1.25.40.10 833 978 2.4E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS15775 c8989a3a17f964e49236cfd8ba56fca2 1005 SUPERFAMILY SSF46894 2 88 1.39E-14 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS16500 de6678848e30bc56af0260a5f21da849 128 Pfam PF13466 STAS domain 23 100 3.0E-11 T 28-03-2018 IPR002645 STAS domain CNX65_RS16500 de6678848e30bc56af0260a5f21da849 128 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 11 110 1.8E-25 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS16500 de6678848e30bc56af0260a5f21da849 128 Gene3D G3DSA:3.30.750.24 6 118 4.6E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS16500 de6678848e30bc56af0260a5f21da849 128 SUPERFAMILY SSF52091 14 114 1.51E-18 T 28-03-2018 IPR002645 STAS domain CNX65_RS22790 46889d2ea8ad0bda129cb7f7e0adb392 374 Pfam PF14907 Uncharacterised nucleotidyltransferase 37 316 6.0E-42 T 28-03-2018 CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 SUPERFAMILY SSF55048 128 180 1.02E-10 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 SUPERFAMILY SSF52151 2 120 2.01E-60 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 SUPERFAMILY SSF52151 182 303 2.01E-60 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 Gene3D G3DSA:3.40.366.10 185 304 2.1E-24 T 28-03-2018 CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 5 291 1.0E-13 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 Pfam PF00698 Acyl transferase domain 7 282 1.5E-26 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 Gene3D G3DSA:3.30.70.250 138 184 5.2E-11 T 28-03-2018 CNX65_RS06555 e6f0275d628b6601825e727f1b5c5856 306 Gene3D G3DSA:3.40.366.10 1 137 4.7E-26 T 28-03-2018 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 Gene3D G3DSA:3.40.50.300 291 560 8.7E-73 T 28-03-2018 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 Gene3D G3DSA:3.40.50.300 2 274 4.9E-70 T 28-03-2018 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 Pfam PF00005 ABC transporter 316 467 2.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 Pfam PF00005 ABC transporter 26 182 2.9E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 ProSitePatterns PS00211 ABC transporters family signature. 439 453 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 SUPERFAMILY SSF52540 5 254 2.88E-66 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 SUPERFAMILY SSF52540 295 537 1.41E-69 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 SMART SM00382 324 524 1.5E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 SMART SM00382 34 232 7.4E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 262 0.016 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS12455 70b5c514d14b12d0e25bfc4468e5199c 563 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 518 550 2.2E-5 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS34255 c00b7af9c01dcad4ef2c5d2024b259c2 235 Gene3D G3DSA:3.30.1330.30 1 79 7.4E-6 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS34255 c00b7af9c01dcad4ef2c5d2024b259c2 235 SMART SM00967 6 84 0.0027 T 28-03-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 CNX65_RS34255 c00b7af9c01dcad4ef2c5d2024b259c2 235 Gene3D G3DSA:3.40.1280.10 80 234 2.6E-32 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CNX65_RS34255 c00b7af9c01dcad4ef2c5d2024b259c2 235 SUPERFAMILY SSF75217 85 227 3.86E-30 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CNX65_RS34255 c00b7af9c01dcad4ef2c5d2024b259c2 235 Pfam PF00588 SpoU rRNA Methylase family 95 224 1.7E-25 T 28-03-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 CNX65_RS18360 08bfdba1e5cf3a4bab586694afacc09d 280 Pfam PF12679 ABC-2 family transporter protein 77 278 2.9E-9 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CNX65_RS31760 dc0b8998b38d137eb4d2b2566aa30f19 115 Pfam PF01934 Protein of unknown function DUF86 14 107 3.8E-17 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CNX65_RS31760 dc0b8998b38d137eb4d2b2566aa30f19 115 Gene3D G3DSA:1.20.120.580 26 113 4.5E-12 T 28-03-2018 IPR008201 Protein of unknown function DUF86 CNX65_RS00975 17c8a1d2cb83bd4267cbeb136248495e 310 SUPERFAMILY SSF161098 101 291 1.7E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS00975 17c8a1d2cb83bd4267cbeb136248495e 310 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 72 1.6E-11 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CNX65_RS00975 17c8a1d2cb83bd4267cbeb136248495e 310 Gene3D G3DSA:1.10.3720.10 26 298 1.5E-43 T 28-03-2018 CNX65_RS00975 17c8a1d2cb83bd4267cbeb136248495e 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 124 309 3.9E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12990 f34d7c331a5716659d66d1469bfe26a2 656 SUPERFAMILY SSF50370 527 652 7.04E-22 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS12990 f34d7c331a5716659d66d1469bfe26a2 656 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 556 641 2.4E-13 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS12990 f34d7c331a5716659d66d1469bfe26a2 656 Gene3D G3DSA:2.60.40.1180 415 520 3.2E-20 T 28-03-2018 CNX65_RS12990 f34d7c331a5716659d66d1469bfe26a2 656 Gene3D G3DSA:2.80.10.50 521 656 5.7E-23 T 28-03-2018 CNX65_RS12990 f34d7c331a5716659d66d1469bfe26a2 656 Gene3D G3DSA:3.20.20.80 43 414 6.5E-82 T 28-03-2018 CNX65_RS12990 f34d7c331a5716659d66d1469bfe26a2 656 Pfam PF14587 O-Glycosyl hydrolase family 30 42 271 2.7E-16 T 28-03-2018 CNX65_RS12990 f34d7c331a5716659d66d1469bfe26a2 656 SUPERFAMILY SSF51445 46 421 1.05E-32 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS08540 24faec78bb033329908e0532d0e7df2d 531 SUPERFAMILY SSF52096 20 269 5.98E-60 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS08540 24faec78bb033329908e0532d0e7df2d 531 SUPERFAMILY SSF52096 232 512 1.76E-72 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS08540 24faec78bb033329908e0532d0e7df2d 531 Gene3D G3DSA:3.90.226.10 9 271 5.1E-55 T 28-03-2018 CNX65_RS08540 24faec78bb033329908e0532d0e7df2d 531 Gene3D G3DSA:3.90.226.10 272 525 6.1E-56 T 28-03-2018 CNX65_RS08540 24faec78bb033329908e0532d0e7df2d 531 Pfam PF01039 Carboxyl transferase domain 48 519 4.9E-130 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 Gene3D G3DSA:1.20.1560.10 18 346 7.3E-60 T 28-03-2018 CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 Gene3D G3DSA:3.40.50.300 350 595 1.8E-66 T 28-03-2018 CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 SMART SM00382 382 568 4.6E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 SUPERFAMILY SSF90123 23 346 1.57E-71 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 Pfam PF00005 ABC transporter 376 522 1.5E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 Pfam PF00664 ABC transporter transmembrane region 37 306 2.7E-41 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 ProSitePatterns PS00211 ABC transporters family signature. 494 508 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS02645 ce6d8a8bacedc6a8670eefe326b8bc08 597 SUPERFAMILY SSF52540 346 591 2.61E-83 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03730 f938eaf377f90509203185db6315bae4 126 SUPERFAMILY SSF55811 1 123 6.77E-29 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS03730 f938eaf377f90509203185db6315bae4 126 Gene3D G3DSA:3.90.79.10 1 126 2.6E-26 T 28-03-2018 CNX65_RS03730 f938eaf377f90509203185db6315bae4 126 Pfam PF00293 NUDIX domain 2 119 1.8E-17 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS03730 f938eaf377f90509203185db6315bae4 126 PRINTS PR00502 NUDIX hydrolase family signature 42 57 7.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS03730 f938eaf377f90509203185db6315bae4 126 PRINTS PR00502 NUDIX hydrolase family signature 28 42 7.4E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS13160 ac72dc4160c1d5dc972406bdf2de77e1 80 Gene3D G3DSA:3.30.1390.10 8 76 7.1E-9 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CNX65_RS13160 ac72dc4160c1d5dc972406bdf2de77e1 80 SUPERFAMILY SSF54736 6 75 1.2E-5 T 28-03-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like CNX65_RS14195 c73fe522ea7d226001943bb844671079 560 SUPERFAMILY SSF140453 69 149 6.67E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS14195 c73fe522ea7d226001943bb844671079 560 Gene3D G3DSA:1.10.287.850 65 173 3.5E-7 T 28-03-2018 CNX65_RS10545 1f8b2bd1d75f0351fcf131fbf22fa7f5 516 Gene3D G3DSA:1.10.10.60 427 493 4.4E-6 T 28-03-2018 CNX65_RS10545 1f8b2bd1d75f0351fcf131fbf22fa7f5 516 Pfam PF13556 PucR C-terminal helix-turn-helix domain 457 515 1.8E-23 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS10545 1f8b2bd1d75f0351fcf131fbf22fa7f5 516 Pfam PF07905 Purine catabolism regulatory protein-like family 2 110 1.2E-20 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 SUPERFAMILY SSF51735 171 300 3.44E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 SUPERFAMILY SSF52283 5 139 2.98E-26 T 28-03-2018 CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 SUPERFAMILY SSF52283 302 327 2.98E-26 T 28-03-2018 CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 PIRSF PIRSF018250 1 343 1.1E-121 T 28-03-2018 IPR027281 Saccharopine dehydrogenase [NAD(+), L-lysine-forming] GO:0004754|GO:0009085 KEGG: 00300+1.5.1.7|KEGG: 00310+1.5.1.7 CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 6 139 2.9E-23 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 SMART SM01003 6 140 2.5E-24 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 SMART SM01002 168 294 6.3E-5 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 Gene3D G3DSA:3.40.50.720 143 276 4.9E-6 T 28-03-2018 CNX65_RS17940 0f75b3e9177916e94407c6f0856256b5 345 Gene3D G3DSA:3.40.50.720 2 142 1.7E-41 T 28-03-2018 CNX65_RS09205 9557eb36d15403078ebdba69fe6ea802 291 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 284 1.7E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09205 9557eb36d15403078ebdba69fe6ea802 291 Gene3D G3DSA:1.10.3720.10 60 287 3.2E-43 T 28-03-2018 CNX65_RS09205 9557eb36d15403078ebdba69fe6ea802 291 SUPERFAMILY SSF161098 51 279 7.98E-57 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09205 9557eb36d15403078ebdba69fe6ea802 291 Gene3D G3DSA:1.20.58.370 1 39 2.2E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 Pfam PF12705 PD-(D/E)XK nuclease superfamily 794 1040 2.3E-38 T 28-03-2018 CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 Gene3D G3DSA:3.90.320.10 754 960 3.9E-11 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 Gene3D G3DSA:3.40.50.300 17 309 2.8E-33 T 28-03-2018 CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 SUPERFAMILY SSF52540 20 710 3.37E-84 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 Pfam PF00580 UvrD/REP helicase N-terminal domain 24 305 5.2E-31 T 28-03-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 Gene3D G3DSA:3.40.50.300 315 418 1.7E-10 T 28-03-2018 CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 Gene3D G3DSA:1.10.486.10 422 595 9.4E-25 T 28-03-2018 CNX65_RS04205 800def74ae6444945eb223fb272a85dd 1050 Pfam PF13361 UvrD-like helicase C-terminal domain 345 694 1.5E-16 T 28-03-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 492 1.6E-17 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 Gene3D G3DSA:3.40.50.980 165 316 1.9E-49 T 28-03-2018 CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 SUPERFAMILY SSF56801 6 501 1.96E-135 T 28-03-2018 CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 Gene3D G3DSA:2.30.38.10 317 401 1.4E-21 T 28-03-2018 CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 Gene3D G3DSA:3.40.50.980 4 164 1.5E-34 T 28-03-2018 CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 ProSitePatterns PS00455 Putative AMP-binding domain signature. 158 169 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 Gene3D G3DSA:3.30.300.30 403 502 3.9E-27 T 28-03-2018 CNX65_RS33190 f296c341baab20d785938dea4ba11e38 503 Pfam PF00501 AMP-binding enzyme 13 408 4.0E-89 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 Gene3D G3DSA:3.40.50.300 800 1021 2.7E-50 T 28-03-2018 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 SUPERFAMILY SSF52540 820 1018 6.81E-49 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 Pfam PF00664 ABC transporter transmembrane region 33 283 1.3E-19 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 Gene3D G3DSA:3.40.50.300 329 520 5.6E-42 T 28-03-2018 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 Gene3D G3DSA:1.20.1560.10 8 325 1.7E-32 T 28-03-2018 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 SMART SM00382 854 1021 2.6E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 SMART SM00382 363 523 1.6E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 SUPERFAMILY SSF90123 23 325 7.19E-39 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 TIGRFAM TIGR02857 CydD: thiol reductant ABC exporter, CydD subunit 28 510 8.1E-136 T 28-03-2018 IPR014216 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydD GO:0005524|GO:0016020|GO:0042883 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 ProSitePatterns PS00211 ABC transporters family signature. 947 961 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 Gene3D G3DSA:1.20.1560.10 531 776 1.2E-10 T 28-03-2018 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 Pfam PF00005 ABC transporter 356 475 1.3E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 Pfam PF00005 ABC transporter 846 975 7.6E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 TIGRFAM TIGR02868 CydC: thiol reductant ABC exporter, CydC subunit 533 1005 1.2E-120 T 28-03-2018 IPR014223 ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease/ATP-binding protein CydC GO:0006810|GO:0016021|GO:0042626 CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 SUPERFAMILY SSF52540 331 514 1.72E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00480 0c91ef015c3703ef7cee2b4b311ebf5c 1021 SUPERFAMILY SSF90123 536 794 7.06E-20 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS31945 6a1d1e4cdedc1c18e424995e95cd0ddc 224 SUPERFAMILY SSF51261 85 217 1.15E-45 T 28-03-2018 IPR011055 Duplicated hybrid motif CNX65_RS31945 6a1d1e4cdedc1c18e424995e95cd0ddc 224 Pfam PF01551 Peptidase family M23 117 209 2.9E-29 T 28-03-2018 IPR016047 Peptidase M23 CNX65_RS31945 6a1d1e4cdedc1c18e424995e95cd0ddc 224 Gene3D G3DSA:2.70.70.10 62 220 4.3E-46 T 28-03-2018 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 SUPERFAMILY SSF58104 242 535 1.26E-62 T 28-03-2018 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 Gene3D G3DSA:1.10.287.950 151 320 2.1E-7 T 28-03-2018 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 Gene3D G3DSA:1.10.287.950 321 538 1.1E-45 T 28-03-2018 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 Pfam PF00672 HAMP domain 222 270 3.9E-13 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 SMART SM00283 282 536 2.0E-51 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 SMART SM00304 222 274 6.5E-16 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 SMART SM00304 477 533 6.3 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS08745 2da47a85ca0b32b155f93b58aff74da7 538 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 345 506 5.3E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS30475 0d2acdac6ea92b7a79c4340812e66761 428 SUPERFAMILY SSF51679 3 425 7.72E-102 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS30475 0d2acdac6ea92b7a79c4340812e66761 428 Pfam PF00296 Luciferase-like monooxygenase 23 374 3.0E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS30475 0d2acdac6ea92b7a79c4340812e66761 428 Gene3D G3DSA:3.20.20.30 1 427 9.9E-91 T 28-03-2018 CNX65_RS30475 0d2acdac6ea92b7a79c4340812e66761 428 PIRSF PIRSF000337 1 427 4.4E-139 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CNX65_RS30475 0d2acdac6ea92b7a79c4340812e66761 428 TIGRFAM TIGR03860 FMN_nitrolo: FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family 15 421 9.6E-111 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CNX65_RS21555 83cc4105a449a37c47a642847666edd7 412 SMART SM00901 148 257 1.1E-24 T 28-03-2018 IPR014966 FRG domain CNX65_RS21555 83cc4105a449a37c47a642847666edd7 412 Pfam PF08867 FRG domain 152 245 5.8E-20 T 28-03-2018 IPR014966 FRG domain CNX65_RS26915 4fc0ee7a6d6afbf8b134c2ff1bf61be8 205 Gene3D G3DSA:3.40.50.880 2 205 3.1E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS26915 4fc0ee7a6d6afbf8b134c2ff1bf61be8 205 Pfam PF01965 DJ-1/PfpI family 5 178 3.1E-17 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS26915 4fc0ee7a6d6afbf8b134c2ff1bf61be8 205 SUPERFAMILY SSF52317 4 196 5.67E-30 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS25460 ea704b226e7fcddd5ee6de426188c582 243 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 70 231 7.2E-24 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25460 ea704b226e7fcddd5ee6de426188c582 243 Gene3D G3DSA:1.10.1740.10 48 168 6.1E-20 T 28-03-2018 CNX65_RS25460 ea704b226e7fcddd5ee6de426188c582 243 Gene3D G3DSA:1.10.10.10 169 238 1.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25460 ea704b226e7fcddd5ee6de426188c582 243 Pfam PF04542 Sigma-70 region 2 74 145 1.8E-11 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25460 ea704b226e7fcddd5ee6de426188c582 243 SUPERFAMILY SSF88659 162 232 5.98E-15 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25460 ea704b226e7fcddd5ee6de426188c582 243 Pfam PF08281 Sigma-70, region 4 178 228 1.3E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS25460 ea704b226e7fcddd5ee6de426188c582 243 SUPERFAMILY SSF88946 51 164 2.75E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS22765 73995e106dfde89b6304f1ad9b2ee7b4 272 Gene3D G3DSA:3.40.50.150 26 270 9.8E-37 T 28-03-2018 CNX65_RS22765 73995e106dfde89b6304f1ad9b2ee7b4 272 Pfam PF08241 Methyltransferase domain 68 163 6.4E-26 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS22765 73995e106dfde89b6304f1ad9b2ee7b4 272 SUPERFAMILY SSF53335 45 220 1.3E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 SMART SM00357 3 67 3.5E-27 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 SUPERFAMILY SSF50249 2 66 5.83E-23 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 Pfam PF00313 'Cold-shock' DNA-binding domain 4 66 7.1E-27 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 PIRSF PIRSF002599 1 68 6.9E-22 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 Gene3D G3DSA:2.40.50.140 1 68 2.5E-27 T 28-03-2018 CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 PRINTS PR00050 Cold shock protein signature 24 33 3.2E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 PRINTS PR00050 Cold shock protein signature 39 57 3.2E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 PRINTS PR00050 Cold shock protein signature 4 19 3.2E-17 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS02230 0f65b306f288df54c5165d56838d8676 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 28-03-2018 IPR019844 Cold-shock conserved site CNX65_RS11795 045995b0f3c467f5ae50e9a262adf23e 129 Gene3D G3DSA:3.40.50.2300 1 120 8.0E-28 T 28-03-2018 CNX65_RS11795 045995b0f3c467f5ae50e9a262adf23e 129 SUPERFAMILY SSF52172 2 118 1.42E-28 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS11795 045995b0f3c467f5ae50e9a262adf23e 129 SMART SM00448 1 117 7.0E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11795 045995b0f3c467f5ae50e9a262adf23e 129 Pfam PF00072 Response regulator receiver domain 4 116 3.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS31845 d5759365375fb4e321bc96183305af3c 239 SUPERFAMILY SSF46689 5 78 1.07E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS31845 d5759365375fb4e321bc96183305af3c 239 Pfam PF00440 Bacterial regulatory proteins, tetR family 21 61 2.1E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS31845 d5759365375fb4e321bc96183305af3c 239 Gene3D G3DSA:1.10.357.10 65 238 5.4E-32 T 28-03-2018 CNX65_RS31845 d5759365375fb4e321bc96183305af3c 239 Gene3D G3DSA:1.10.10.60 2 64 2.4E-16 T 28-03-2018 CNX65_RS31845 d5759365375fb4e321bc96183305af3c 239 SUPERFAMILY SSF48498 90 237 1.85E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS19860 16f211db8d85b0fadba82de4b82462b0 457 Gene3D G3DSA:1.25.40.10 185 452 1.3E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS19860 16f211db8d85b0fadba82de4b82462b0 457 Gene3D G3DSA:1.10.260.40 3 78 3.7E-4 T 28-03-2018 CNX65_RS02875 ab4d7c9f827f57077639f2bd1e012e3e 277 Pfam PF04672 S-adenosyl methyltransferase 10 276 6.0E-83 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS02875 ab4d7c9f827f57077639f2bd1e012e3e 277 Gene3D G3DSA:3.40.50.150 3 276 2.1E-45 T 28-03-2018 CNX65_RS02875 ab4d7c9f827f57077639f2bd1e012e3e 277 SUPERFAMILY SSF53335 18 258 6.98E-40 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS02875 ab4d7c9f827f57077639f2bd1e012e3e 277 PIRSF PIRSF017393 3 277 1.4E-89 T 28-03-2018 IPR006764 S-adenosyl-L-methionine dependent methyltransferase, SAV2177 type CNX65_RS05995 3f25884af24d9c1e2d085114e5b2720e 770 SMART SM00849 523 720 7.1E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05995 3f25884af24d9c1e2d085114e5b2720e 770 Gene3D G3DSA:3.60.15.10 515 716 6.9E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05995 3f25884af24d9c1e2d085114e5b2720e 770 Pfam PF00753 Metallo-beta-lactamase superfamily 521 697 9.4E-13 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05995 3f25884af24d9c1e2d085114e5b2720e 770 SUPERFAMILY SSF56281 509 752 8.78E-42 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05995 3f25884af24d9c1e2d085114e5b2720e 770 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 193 748 9.3E-63 T 28-03-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 CNX65_RS05995 3f25884af24d9c1e2d085114e5b2720e 770 Pfam PF03772 Competence protein 216 481 3.1E-52 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CNX65_RS05995 3f25884af24d9c1e2d085114e5b2720e 770 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 238 407 4.0E-20 T 28-03-2018 IPR004477 ComEC/Rec2-related protein CNX65_RS18525 1925724d449346b8e19b1fd97481bf60 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.7E-15 T 28-03-2018 CNX65_RS18525 1925724d449346b8e19b1fd97481bf60 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 300 1.7E-15 T 28-03-2018 CNX65_RS18525 1925724d449346b8e19b1fd97481bf60 371 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 1.7E-15 T 28-03-2018 CNX65_RS18525 1925724d449346b8e19b1fd97481bf60 371 Pfam PF01494 FAD binding domain 3 68 2.7E-7 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS18525 1925724d449346b8e19b1fd97481bf60 371 SUPERFAMILY SSF51905 4 163 1.73E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18525 1925724d449346b8e19b1fd97481bf60 371 SUPERFAMILY SSF51905 280 364 1.73E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18525 1925724d449346b8e19b1fd97481bf60 371 Gene3D G3DSA:3.50.50.60 1 353 4.3E-32 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29875 07abe2877263600277697bc553dba00a 370 SUPERFAMILY SSF48452 177 229 2.97E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29875 07abe2877263600277697bc553dba00a 370 SUPERFAMILY SSF48452 301 353 2.97E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29875 07abe2877263600277697bc553dba00a 370 Gene3D G3DSA:1.25.40.10 168 370 3.4E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29245 878d5fcaa90d8a3566a9cb7c05bfa1ba 235 Pfam PF00188 Cysteine-rich secretory protein family 122 233 1.0E-19 T 28-03-2018 IPR014044 CAP domain CNX65_RS29245 878d5fcaa90d8a3566a9cb7c05bfa1ba 235 SUPERFAMILY SSF55797 119 234 1.05E-21 T 28-03-2018 IPR014044 CAP domain CNX65_RS29245 878d5fcaa90d8a3566a9cb7c05bfa1ba 235 Gene3D G3DSA:3.40.33.10 112 233 1.3E-17 T 28-03-2018 IPR014044 CAP domain CNX65_RS00500 afb68c7233e40bc85097076849217dd0 199 Pfam PF01661 Macro domain 61 183 2.0E-5 T 28-03-2018 IPR002589 Macro domain CNX65_RS00500 afb68c7233e40bc85097076849217dd0 199 SUPERFAMILY SSF52949 19 193 7.74E-16 T 28-03-2018 CNX65_RS00500 afb68c7233e40bc85097076849217dd0 199 Gene3D G3DSA:3.40.220.10 25 195 4.3E-19 T 28-03-2018 CNX65_RS15180 7094477983db17c52f0343a8c05d38a7 169 Gene3D G3DSA:3.40.50.360 3 164 5.0E-14 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS15180 7094477983db17c52f0343a8c05d38a7 169 SUPERFAMILY SSF52218 1 77 8.93E-11 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS23635 f314430f775ddd2f572dd3c66db05175 228 Gene3D G3DSA:1.10.10.10 12 212 6.8E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23635 f314430f775ddd2f572dd3c66db05175 228 SUPERFAMILY SSF46785 19 199 1.21E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23635 f314430f775ddd2f572dd3c66db05175 228 Pfam PF09339 IclR helix-turn-helix domain 28 69 4.1E-6 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS05525 76ca476f3616203aa9f14b9961bd5cbf 403 SMART SM00530 8 64 2.5E-15 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS05525 76ca476f3616203aa9f14b9961bd5cbf 403 Gene3D G3DSA:1.25.40.10 109 377 2.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05525 76ca476f3616203aa9f14b9961bd5cbf 403 SUPERFAMILY SSF47413 5 67 1.15E-14 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS05525 76ca476f3616203aa9f14b9961bd5cbf 403 Pfam PF01381 Helix-turn-helix 9 62 1.1E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS05525 76ca476f3616203aa9f14b9961bd5cbf 403 Gene3D G3DSA:1.10.260.40 2 79 7.6E-18 T 28-03-2018 CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 SMART SM00354 17 87 2.2E-7 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 Gene3D G3DSA:1.10.260.40 16 72 6.3E-13 T 28-03-2018 CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 Pfam PF13377 Periplasmic binding protein-like domain 188 352 1.1E-29 T 28-03-2018 CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 Gene3D G3DSA:3.40.50.2300 73 184 1.7E-18 T 28-03-2018 CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 Gene3D G3DSA:3.40.50.2300 185 355 8.8E-43 T 28-03-2018 CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 SUPERFAMILY SSF53822 90 353 1.63E-49 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 SUPERFAMILY SSF47413 18 68 6.84E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS16575 bc99862f907b4b9cf572ea3b72393513 358 Pfam PF00356 Bacterial regulatory proteins, lacI family 19 66 3.2E-8 T 28-03-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 CNX65_RS22110 25ced08da9675d5e24ad6dbf96f4cc15 363 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 218 329 1.7E-17 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS22110 25ced08da9675d5e24ad6dbf96f4cc15 363 SMART SM00833 215 329 5.5E-32 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS22110 25ced08da9675d5e24ad6dbf96f4cc15 363 Gene3D G3DSA:3.30.1220.10 213 329 6.2E-17 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS22110 25ced08da9675d5e24ad6dbf96f4cc15 363 Gene3D G3DSA:3.40.1110.10 77 212 0.0018 T 28-03-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 CNX65_RS22110 25ced08da9675d5e24ad6dbf96f4cc15 363 SUPERFAMILY SSF90002 218 329 4.45E-10 T 28-03-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal CNX65_RS23975 0d9776eca8e2863adf60e95bc2b983cd 112 Pfam PF04075 F420H(2)-dependent quinone reductase 24 74 1.5E-5 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CNX65_RS23975 0d9776eca8e2863adf60e95bc2b983cd 112 Gene3D G3DSA:2.30.110.10 4 110 9.3E-13 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 Gene3D G3DSA:3.30.450.40 185 340 5.7E-36 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 Gene3D G3DSA:1.10.10.10 2 86 1.3E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 SUPERFAMILY SSF46785 3 84 3.6E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 Pfam PF08220 DeoR-like helix-turn-helix domain 16 63 1.2E-5 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 SUPERFAMILY SSF55781 72 338 7.85E-56 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 4 335 2.4E-93 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 PIRSF PIRSF005485 1 340 1.3E-102 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 Pfam PF01628 HrcA protein C terminal domain 104 323 7.5E-60 T 28-03-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 CNX65_RS06185 955860a1c836ba27d40d36d19e56e289 340 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 2 330 27.702 T 28-03-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 CNX65_RS31560 ae7e2ed21e426e7ffa2ab386e5e127d1 329 SUPERFAMILY SSF55347 130 292 1.29E-33 T 28-03-2018 CNX65_RS31560 ae7e2ed21e426e7ffa2ab386e5e127d1 329 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 5 123 4.4E-25 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS31560 ae7e2ed21e426e7ffa2ab386e5e127d1 329 SUPERFAMILY SSF51735 2 156 2.17E-49 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS31560 ae7e2ed21e426e7ffa2ab386e5e127d1 329 Gene3D G3DSA:3.40.50.720 1 144 9.4E-44 T 28-03-2018 CNX65_RS31560 ae7e2ed21e426e7ffa2ab386e5e127d1 329 Gene3D G3DSA:3.30.360.10 145 320 5.9E-38 T 28-03-2018 CNX65_RS21145 6b618f8ba05ea30f804ca957ef6bcd4b 621 Gene3D G3DSA:3.20.20.80 37 421 2.0E-46 T 28-03-2018 CNX65_RS21145 6b618f8ba05ea30f804ca957ef6bcd4b 621 SUPERFAMILY SSF51445 43 423 2.57E-47 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS21145 6b618f8ba05ea30f804ca957ef6bcd4b 621 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 99 394 3.5E-29 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS21145 6b618f8ba05ea30f804ca957ef6bcd4b 621 ProSitePatterns PS00659 Glycosyl hydrolases family 5 signature. 213 222 - T 28-03-2018 IPR018087 Glycoside hydrolase, family 5, conserved site GO:0004553|GO:0005975 CNX65_RS24545 a92a64dfbd08d56ffbfaadb26b2030f7 189 Pfam PF14024 Protein of unknown function (DUF4240) 1 139 2.2E-36 T 28-03-2018 IPR025334 Domain of unknown function (DUF4240 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 SUPERFAMILY SSF51905 2 289 1.66E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 280 3.4E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 Gene3D G3DSA:3.50.50.60 1 134 1.1E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 265 272 3.9E-10 T 28-03-2018 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 3.9E-10 T 28-03-2018 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 3.9E-10 T 28-03-2018 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 3.0E-13 T 28-03-2018 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.0E-13 T 28-03-2018 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 3.0E-13 T 28-03-2018 CNX65_RS29260 f995c3452cd3db76bc4a856ab8e67450 373 Gene3D G3DSA:3.50.50.60 144 326 7.9E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS31825 ada44cd0e44dc72dcc2dcce7a6145ba5 265 Pfam PF06182 ABC-2 family transporter protein 36 264 4.8E-55 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CNX65_RS14160 75037ed94398abe0ebd6f12caafde8c3 105 SUPERFAMILY SSF52091 3 103 8.44E-14 T 28-03-2018 IPR002645 STAS domain CNX65_RS14160 75037ed94398abe0ebd6f12caafde8c3 105 Gene3D G3DSA:3.30.750.24 1 105 2.8E-11 T 28-03-2018 IPR002645 STAS domain CNX65_RS05535 2836d165a287d626d9b3479fe4dc3d4a 79 Pfam PF16827 zinc-finger 6 67 1.8E-23 T 28-03-2018 IPR031795 Putative zinc-finger containing protein CNX65_RS06955 b0e3c74ed08193f075738fc00f240013 207 Gene3D G3DSA:3.90.1720.10 33 192 8.0E-7 T 28-03-2018 CNX65_RS10570 de4c523cae9994a72a1413d6b3fa16e7 197 Pfam PF03029 Conserved hypothetical ATP binding protein 23 191 2.5E-26 T 28-03-2018 IPR004130 GPN-loop GTPase CNX65_RS10570 de4c523cae9994a72a1413d6b3fa16e7 197 SUPERFAMILY SSF52540 17 191 5.86E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10570 de4c523cae9994a72a1413d6b3fa16e7 197 Gene3D G3DSA:3.40.50.300 12 196 5.3E-21 T 28-03-2018 CNX65_RS19645 a35060ee5c8c06007af45b5766dd55f1 305 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 37 284 5.3E-69 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CNX65_RS19645 a35060ee5c8c06007af45b5766dd55f1 305 SUPERFAMILY SSF56112 20 284 2.33E-30 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS19645 a35060ee5c8c06007af45b5766dd55f1 305 Gene3D G3DSA:3.90.1200.10 111 290 3.5E-10 T 28-03-2018 CNX65_RS08775 9653f6d7ef08b3af87bfa590c163ff06 530 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 10 32 2.5E-6 T 28-03-2018 CNX65_RS08775 9653f6d7ef08b3af87bfa590c163ff06 530 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 257 271 2.5E-6 T 28-03-2018 CNX65_RS08775 9653f6d7ef08b3af87bfa590c163ff06 530 SUPERFAMILY SSF51905 466 506 1.25E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS08775 9653f6d7ef08b3af87bfa590c163ff06 530 SUPERFAMILY SSF51905 9 330 1.25E-39 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS08775 9653f6d7ef08b3af87bfa590c163ff06 530 Gene3D G3DSA:3.50.50.60 3 510 3.4E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS08775 9653f6d7ef08b3af87bfa590c163ff06 530 Pfam PF01593 Flavin containing amine oxidoreductase 20 285 2.6E-11 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 Pfam PF01245 Ribosomal protein L19 4 112 6.2E-50 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 1 113 30.088 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 PRINTS PR00061 Ribosomal protein L19 signature 3 32 1.1E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 PRINTS PR00061 Ribosomal protein L19 signature 33 62 1.1E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 PRINTS PR00061 Ribosomal protein L19 signature 87 112 1.1E-41 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 2 112 4.6E-49 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 SUPERFAMILY SSF50104 1 114 6.62E-47 T 28-03-2018 IPR008991 Translation protein SH3-like domain CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 ProSitePatterns PS01015 Ribosomal protein L19 signature. 85 100 - T 28-03-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS29060 ac9990778acb0c26c34bb70612471baa 119 PIRSF PIRSF002191 1 118 6.0E-51 T 28-03-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS06165 d56f26348a8894e886f5f2a3bf5ac288 228 PIRSF PIRSF000857 2 228 1.2E-83 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CNX65_RS06165 d56f26348a8894e886f5f2a3bf5ac288 228 Gene3D G3DSA:3.40.50.620 3 228 4.7E-32 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS06165 d56f26348a8894e886f5f2a3bf5ac288 228 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 21 227 1.3E-55 T 28-03-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 CNX65_RS06165 d56f26348a8894e886f5f2a3bf5ac288 228 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 39 203 1.6E-38 T 28-03-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824|GO:0008152 Reactome: R-HSA-196843 CNX65_RS06165 d56f26348a8894e886f5f2a3bf5ac288 228 SUPERFAMILY SSF52402 12 192 3.77E-37 T 28-03-2018 CNX65_RS23445 ac8c65ff031edac3a00e6c14fa02a56a 174 Gene3D G3DSA:1.10.10.10 2 121 8.1E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23445 ac8c65ff031edac3a00e6c14fa02a56a 174 Pfam PF09860 Uncharacterized protein conserved in bacteria (DUF2087) 105 173 1.3E-19 T 28-03-2018 IPR018656 Domain of unknown function DUF2087 CNX65_RS23445 ac8c65ff031edac3a00e6c14fa02a56a 174 SUPERFAMILY SSF46785 13 69 1.85E-6 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16420 057d508bf3227ec49352432bafb56460 206 Pfam PF16316 Domain of unknown function (DUF4956) 10 179 7.9E-54 T 28-03-2018 IPR032531 Protein of unknown function DUF4956 CNX65_RS03930 91d44c94db4a210e7d7db143f83de59f 194 SUPERFAMILY SSF88946 27 108 1.53E-24 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS03930 91d44c94db4a210e7d7db143f83de59f 194 SUPERFAMILY SSF88659 106 186 8.22E-18 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS03930 91d44c94db4a210e7d7db143f83de59f 194 Pfam PF04542 Sigma-70 region 2 31 96 4.0E-21 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS03930 91d44c94db4a210e7d7db143f83de59f 194 Gene3D G3DSA:1.10.10.10 94 191 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03930 91d44c94db4a210e7d7db143f83de59f 194 Gene3D G3DSA:1.10.1740.10 19 93 1.2E-23 T 28-03-2018 CNX65_RS03930 91d44c94db4a210e7d7db143f83de59f 194 Pfam PF08281 Sigma-70, region 4 129 179 3.3E-17 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS03930 91d44c94db4a210e7d7db143f83de59f 194 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 183 1.6E-31 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 SMART SM00612 82 131 4.5E-5 T 28-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 SMART SM00612 243 291 0.098 T 28-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 SMART SM00612 30 81 1.3 T 28-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 SMART SM00612 194 242 1.8E-5 T 28-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 SUPERFAMILY SSF117281 160 299 8.76E-33 T 28-03-2018 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 SUPERFAMILY SSF117281 7 141 4.84E-28 T 28-03-2018 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 Pfam PF13418 Galactose oxidase, central domain 231 278 7.9E-5 T 28-03-2018 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 Gene3D G3DSA:2.120.10.80 155 311 5.3E-29 T 28-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 Gene3D G3DSA:2.120.10.80 3 151 2.5E-23 T 28-03-2018 IPR015915 Kelch-type beta propeller GO:0005515 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 Pfam PF01344 Kelch motif 71 118 2.6E-7 T 28-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CNX65_RS24165 92a865f0d34de61f7cfe24c2dbf0c372 316 Pfam PF01344 Kelch motif 182 229 4.7E-8 T 28-03-2018 IPR006652 Kelch repeat type 1 GO:0005515 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 SUPERFAMILY SSF47323 314 461 7.72E-31 T 28-03-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 189 207 9.5E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 9.5E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 220 241 9.5E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 9.5E-26 T 28-03-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 3 459 3.5E-127 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 21 309 2.3E-112 T 28-03-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 Gene3D G3DSA:1.20.120.640 303 394 7.1E-18 T 28-03-2018 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 462 34.332 T 28-03-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 SUPERFAMILY SSF52374 4 309 9.65E-82 T 28-03-2018 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 Gene3D G3DSA:3.40.50.620 1 302 2.3E-79 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 Pfam PF09190 DALR domain 340 392 1.6E-9 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CNX65_RS01850 542b68022097351bcd4b54d769aad528 464 SMART SM00840 339 400 3.0E-12 T 28-03-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 CNX65_RS09990 22de6ade1959b78b8fe2b87242dfb1cf 658 Pfam PF01261 Xylose isomerase-like TIM barrel 361 580 7.1E-23 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS09990 22de6ade1959b78b8fe2b87242dfb1cf 658 Gene3D G3DSA:3.20.20.150 322 657 1.2E-43 T 28-03-2018 CNX65_RS09990 22de6ade1959b78b8fe2b87242dfb1cf 658 SUPERFAMILY SSF53067 113 284 6.83E-26 T 28-03-2018 CNX65_RS09990 22de6ade1959b78b8fe2b87242dfb1cf 658 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 110 241 8.8E-10 T 28-03-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 CNX65_RS09990 22de6ade1959b78b8fe2b87242dfb1cf 658 SUPERFAMILY SSF51658 343 649 4.7E-39 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS09990 22de6ade1959b78b8fe2b87242dfb1cf 658 Gene3D G3DSA:3.30.420.40 112 298 6.3E-28 T 28-03-2018 CNX65_RS09990 22de6ade1959b78b8fe2b87242dfb1cf 658 Pfam PF07582 AP endonuclease family 2 C terminus 605 655 1.4E-8 T 28-03-2018 IPR011418 AP endonuclease, family 2, C-terminal CNX65_RS06895 751bc6abf42234ad6457aa5b5cc675cc 170 Pfam PF16473 3' exoribonuclease, RNase T-like 1 158 9.2E-18 T 28-03-2018 IPR033390 3'-5' exoribonuclease Rv2179c-like domain CNX65_RS06895 751bc6abf42234ad6457aa5b5cc675cc 170 Hamap MF_00977 3'-5' exoribonuclease. 1 162 42.407 T 28-03-2018 IPR030853 3-5 exoribonuclease, actinobacteria GO:0000287|GO:0008408 CNX65_RS06895 751bc6abf42234ad6457aa5b5cc675cc 170 SUPERFAMILY SSF53098 3 160 5.06E-6 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS16850 4bbe74e0187303fcfe8f2889b0ca05a6 215 SUPERFAMILY SSF55729 134 206 2.96E-11 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS16850 4bbe74e0187303fcfe8f2889b0ca05a6 215 Pfam PF00583 Acetyltransferase (GNAT) family 147 201 7.2E-6 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS16850 4bbe74e0187303fcfe8f2889b0ca05a6 215 Gene3D G3DSA:3.40.630.30 6 214 1.7E-11 T 28-03-2018 CNX65_RS21025 8f40cc57c21fe3904736a761ef0d79fa 204 Gene3D G3DSA:1.10.357.10 70 200 1.1E-6 T 28-03-2018 CNX65_RS21025 8f40cc57c21fe3904736a761ef0d79fa 204 Gene3D G3DSA:1.10.260.40 7 25 0.22 T 28-03-2018 CNX65_RS21025 8f40cc57c21fe3904736a761ef0d79fa 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 22 35 7.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21025 8f40cc57c21fe3904736a761ef0d79fa 204 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 43 66 7.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21025 8f40cc57c21fe3904736a761ef0d79fa 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 23 68 5.3E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21025 8f40cc57c21fe3904736a761ef0d79fa 204 Gene3D G3DSA:1.10.10.60 26 69 9.7E-19 T 28-03-2018 CNX65_RS21025 8f40cc57c21fe3904736a761ef0d79fa 204 SUPERFAMILY SSF46689 11 74 8.74E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS15170 3a3fc333d9feba0f7c5278816d7ca6e6 249 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 5 93 2.5E-16 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CNX65_RS15170 3a3fc333d9feba0f7c5278816d7ca6e6 249 Gene3D G3DSA:3.40.50.720 2 189 7.2E-24 T 28-03-2018 CNX65_RS15170 3a3fc333d9feba0f7c5278816d7ca6e6 249 SUPERFAMILY SSF51735 5 196 1.26E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS11755 d0558b278a7df9e2f2ff0884e6ac2154 345 Pfam PF00296 Luciferase-like monooxygenase 24 306 1.7E-46 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS11755 d0558b278a7df9e2f2ff0884e6ac2154 345 Gene3D G3DSA:3.20.20.30 2 343 5.9E-79 T 28-03-2018 CNX65_RS11755 d0558b278a7df9e2f2ff0884e6ac2154 345 SUPERFAMILY SSF51679 12 339 5.5E-78 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS11755 d0558b278a7df9e2f2ff0884e6ac2154 345 TIGRFAM TIGR03858 LLM_2I7G: probable oxidoreductase, LLM family 5 338 1.1E-152 T 28-03-2018 IPR022290 Conserved hypothetical protein CHP03858, luciferase-like monooxygenase, putative CNX65_RS16550 f07d9dd81d26b6a8331915d11aad41f9 284 SMART SM00530 6 82 3.0E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS16550 f07d9dd81d26b6a8331915d11aad41f9 284 Gene3D G3DSA:1.10.260.40 7 121 1.8E-11 T 28-03-2018 CNX65_RS16550 f07d9dd81d26b6a8331915d11aad41f9 284 SUPERFAMILY SSF47413 27 83 3.11E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS16550 f07d9dd81d26b6a8331915d11aad41f9 284 Pfam PF13560 Helix-turn-helix domain 15 85 2.5E-12 T 28-03-2018 CNX65_RS29335 bcae996e04ca045b236035655622b45e 312 Pfam PF13560 Helix-turn-helix domain 44 104 4.5E-10 T 28-03-2018 CNX65_RS29335 bcae996e04ca045b236035655622b45e 312 Gene3D G3DSA:1.10.260.40 30 121 1.7E-6 T 28-03-2018 CNX65_RS26900 48b7f99a6b31645cc2e937a947872465 118 Pfam PF01740 STAS domain 17 114 2.4E-17 T 28-03-2018 IPR002645 STAS domain CNX65_RS26900 48b7f99a6b31645cc2e937a947872465 118 SUPERFAMILY SSF52091 14 116 5.1E-23 T 28-03-2018 IPR002645 STAS domain CNX65_RS26900 48b7f99a6b31645cc2e937a947872465 118 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 16 113 3.5E-22 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS26900 48b7f99a6b31645cc2e937a947872465 118 Gene3D G3DSA:3.30.750.24 8 117 7.5E-25 T 28-03-2018 IPR002645 STAS domain CNX65_RS30770 23ad1da6b676cb1d18c9ffd94a57a939 458 Pfam PF00005 ABC transporter 24 162 6.5E-29 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS30770 23ad1da6b676cb1d18c9ffd94a57a939 458 SMART SM00382 32 210 2.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30770 23ad1da6b676cb1d18c9ffd94a57a939 458 SUPERFAMILY SSF52540 5 228 3.89E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30770 23ad1da6b676cb1d18c9ffd94a57a939 458 Gene3D G3DSA:3.40.50.300 6 424 3.6E-62 T 28-03-2018 CNX65_RS30770 23ad1da6b676cb1d18c9ffd94a57a939 458 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS16660 7c80aedde0dc441f77ef2599f9973a67 710 SUPERFAMILY SSF82171 90 420 9.94E-24 T 28-03-2018 CNX65_RS16660 7c80aedde0dc441f77ef2599f9973a67 710 Pfam PF00326 Prolyl oligopeptidase family 494 686 5.7E-37 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS16660 7c80aedde0dc441f77ef2599f9973a67 710 SUPERFAMILY SSF53474 433 685 1.68E-53 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16660 7c80aedde0dc441f77ef2599f9973a67 710 Gene3D G3DSA:2.140.10.30 42 418 6.3E-47 T 28-03-2018 CNX65_RS16660 7c80aedde0dc441f77ef2599f9973a67 710 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 83 403 3.1E-37 T 28-03-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 CNX65_RS16660 7c80aedde0dc441f77ef2599f9973a67 710 Gene3D G3DSA:3.40.50.1820 419 688 2.2E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23420 851514af19bc53b6686fc880c122314f 478 SUPERFAMILY SSF103473 258 461 1.05E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23420 851514af19bc53b6686fc880c122314f 478 SUPERFAMILY SSF103473 13 207 1.05E-60 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23420 851514af19bc53b6686fc880c122314f 478 Gene3D G3DSA:1.20.1250.20 8 202 2.7E-27 T 28-03-2018 CNX65_RS23420 851514af19bc53b6686fc880c122314f 478 Gene3D G3DSA:1.20.1250.20 269 475 2.6E-25 T 28-03-2018 CNX65_RS23420 851514af19bc53b6686fc880c122314f 478 Pfam PF07690 Major Facilitator Superfamily 29 420 1.8E-48 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 117 142 1.5E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 72 94 1.5E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 210 229 1.5E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 42 63 1.5E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 190 209 1.5E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 PRINTS PR00164 ABC-2 type transport system membrane protein signature 154 178 1.5E-23 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 Pfam PF01061 ABC-2 type transporter 26 230 1.9E-17 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS05855 c70fd06970ccd39838a460b279545c4f 268 PIRSF PIRSF006648 4 266 3.4E-25 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS01300 204a66b7e4a860a5e1d23e81a8663d48 371 Gene3D G3DSA:3.40.50.300 143 370 9.3E-27 T 28-03-2018 CNX65_RS01300 204a66b7e4a860a5e1d23e81a8663d48 371 TIGRFAM TIGR03815 CpaE_hom_Actino: helicase/secretion neighborhood CpaE-like protein 37 368 5.4E-96 T 28-03-2018 IPR022521 Conserved hypothetical protein CHP03815, CpaE-like CNX65_RS01300 204a66b7e4a860a5e1d23e81a8663d48 371 SUPERFAMILY SSF52540 142 351 1.7E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22070 8e2b0b1514182805bbbe7fe9b0c657b3 136 SUPERFAMILY SSF52091 24 124 7.46E-19 T 28-03-2018 IPR002645 STAS domain CNX65_RS22070 8e2b0b1514182805bbbe7fe9b0c657b3 136 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 24 117 2.6E-17 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS22070 8e2b0b1514182805bbbe7fe9b0c657b3 136 Pfam PF01740 STAS domain 24 119 2.8E-12 T 28-03-2018 IPR002645 STAS domain CNX65_RS22070 8e2b0b1514182805bbbe7fe9b0c657b3 136 Gene3D G3DSA:3.30.750.24 19 126 1.5E-19 T 28-03-2018 IPR002645 STAS domain CNX65_RS20695 8dceacfbbc58e17e5465bb800daf68c0 127 Gene3D G3DSA:3.10.450.50 76 127 1.4E-4 T 28-03-2018 CNX65_RS20695 8dceacfbbc58e17e5465bb800daf68c0 127 SUPERFAMILY SSF54427 82 124 3.86E-5 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS18735 26619417740f4f85219e26f1e21c3ec5 125 Pfam PF01740 STAS domain 10 96 1.6E-5 T 28-03-2018 IPR002645 STAS domain CNX65_RS18735 26619417740f4f85219e26f1e21c3ec5 125 SUPERFAMILY SSF52091 4 114 1.75E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS18735 26619417740f4f85219e26f1e21c3ec5 125 Gene3D G3DSA:3.30.750.24 1 121 1.7E-9 T 28-03-2018 IPR002645 STAS domain CNX65_RS17280 8806ae597cd699198d53c1ddd319bf8f 104 Gene3D G3DSA:1.10.10.10 2 102 1.4E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17280 8806ae597cd699198d53c1ddd319bf8f 104 Pfam PF03551 Transcriptional regulator PadR-like family 8 81 3.8E-19 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS17280 8806ae597cd699198d53c1ddd319bf8f 104 SUPERFAMILY SSF46785 6 91 1.89E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23680 c29fbc2d5825406dba623f73d3b85b26 306 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 210 236 5.8E-8 T 28-03-2018 IPR022435 Surface-anchored repeat, actinobacteria CNX65_RS23680 c29fbc2d5825406dba623f73d3b85b26 306 TIGRFAM TIGR03773 anch_rpt_wall: putative ABC transporter-associated repeat protein 13 270 1.2E-58 T 28-03-2018 IPR022395 Conserved hypothetical protein CHP03773, ABC transporter-like CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 SMART SM00345 15 72 5.3E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 Gene3D G3DSA:1.10.10.10 2 74 3.0E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 Pfam PF07729 FCD domain 82 204 2.2E-21 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 SUPERFAMILY SSF48008 78 213 9.42E-25 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 SMART SM00895 82 205 3.4E-16 T 28-03-2018 IPR011711 GntR, C-terminal CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 Gene3D G3DSA:1.20.120.530 75 223 1.3E-27 T 28-03-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 Pfam PF00392 Bacterial regulatory proteins, gntR family 17 68 1.2E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS12070 8e8d78c1c0e5a4f78f00f68cedb97fa3 225 SUPERFAMILY SSF46785 4 76 5.69E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03340 13af8865aa94629367dd894cbe38ea2a 168 Pfam PF04417 Protein of unknown function (DUF501) 33 152 1.8E-38 T 28-03-2018 IPR007511 Protein of unknown function DUF501 CNX65_RS16045 a9e0d229af8b20cf16d67b7ab7b9d03d 218 Gene3D G3DSA:3.40.50.1400 2 115 0.0082 T 28-03-2018 CNX65_RS16045 a9e0d229af8b20cf16d67b7ab7b9d03d 218 Gene3D G3DSA:3.40.30.10 117 201 1.5E-18 T 28-03-2018 CNX65_RS16045 a9e0d229af8b20cf16d67b7ab7b9d03d 218 SUPERFAMILY SSF52833 119 197 2.24E-20 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS16045 a9e0d229af8b20cf16d67b7ab7b9d03d 218 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 118 196 8.4E-6 T 28-03-2018 CNX65_RS28040 2495674e8810dc23e103cec76b33f874 381 SUPERFAMILY SSF53383 47 375 1.63E-70 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS28040 2495674e8810dc23e103cec76b33f874 381 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 30 379 5.7E-98 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CNX65_RS28040 2495674e8810dc23e103cec76b33f874 381 Pfam PF00155 Aminotransferase class I and II 48 369 7.1E-54 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS28040 2495674e8810dc23e103cec76b33f874 381 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 28 380 53.775 T 28-03-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 CNX65_RS28040 2495674e8810dc23e103cec76b33f874 381 Gene3D G3DSA:3.90.1150.10 274 380 1.0E-21 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS28040 2495674e8810dc23e103cec76b33f874 381 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 243 252 - T 28-03-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0008152|GO:0016740 CNX65_RS28040 2495674e8810dc23e103cec76b33f874 381 Gene3D G3DSA:3.40.640.10 64 273 1.3E-32 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS21320 3253c66a1d6e9529e7e7a1346db90b81 198 SMART SM01266 14 69 5.5E-12 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CNX65_RS21320 3253c66a1d6e9529e7e7a1346db90b81 198 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 149 177 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CNX65_RS21320 3253c66a1d6e9529e7e7a1346db90b81 198 Pfam PF12464 Maltose acetyltransferase 16 68 6.9E-10 T 28-03-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 CNX65_RS21320 3253c66a1d6e9529e7e7a1346db90b81 198 Gene3D G3DSA:2.160.10.10 9 197 1.3E-49 T 28-03-2018 CNX65_RS21320 3253c66a1d6e9529e7e7a1346db90b81 198 SUPERFAMILY SSF51161 14 194 4.02E-50 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS21320 3253c66a1d6e9529e7e7a1346db90b81 198 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 141 175 5.5E-11 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS24235 e22552017c525c06acf450ad9664b8f7 307 SUPERFAMILY SSF53807 26 288 4.32E-37 T 28-03-2018 CNX65_RS24235 e22552017c525c06acf450ad9664b8f7 307 Gene3D G3DSA:3.40.50.1980 152 307 1.6E-23 T 28-03-2018 CNX65_RS24235 e22552017c525c06acf450ad9664b8f7 307 Pfam PF01497 Periplasmic binding protein 98 284 5.2E-22 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS24235 e22552017c525c06acf450ad9664b8f7 307 Gene3D G3DSA:3.40.50.1980 25 151 3.6E-20 T 28-03-2018 CNX65_RS06145 f8d8be2bfe7e2dfb6ccfa69e5ea3561e 262 Pfam PF00005 ABC transporter 37 177 1.9E-22 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS06145 f8d8be2bfe7e2dfb6ccfa69e5ea3561e 262 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS06145 f8d8be2bfe7e2dfb6ccfa69e5ea3561e 262 SMART SM00382 46 228 7.8E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS06145 f8d8be2bfe7e2dfb6ccfa69e5ea3561e 262 SUPERFAMILY SSF52540 18 243 2.9E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS06145 f8d8be2bfe7e2dfb6ccfa69e5ea3561e 262 Gene3D G3DSA:3.40.50.300 14 252 1.8E-55 T 28-03-2018 CNX65_RS33340 6afb33d8963ce83624069056d2ce51a4 245 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 10 128 4.6E-19 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS33340 6afb33d8963ce83624069056d2ce51a4 245 Gene3D G3DSA:1.20.120.450 1 136 1.6E-15 T 28-03-2018 CNX65_RS33340 6afb33d8963ce83624069056d2ce51a4 245 Pfam PF07398 MDMPI C-terminal domain 146 238 2.9E-8 T 28-03-2018 IPR010872 MDMPI C-terminal CNX65_RS33340 6afb33d8963ce83624069056d2ce51a4 245 SUPERFAMILY SSF109854 2 128 1.04E-9 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS33340 6afb33d8963ce83624069056d2ce51a4 245 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 10 226 4.2E-20 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 Gene3D G3DSA:3.40.50.980 1 139 3.9E-29 T 28-03-2018 CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 Gene3D G3DSA:3.40.50.980 140 299 2.6E-30 T 28-03-2018 CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 Pfam PF00501 AMP-binding enzyme 4 391 6.6E-78 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 SUPERFAMILY SSF56801 3 481 4.71E-122 T 28-03-2018 CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 TIGRFAM TIGR01733 AA-adenyl-dom: amino acid adenylation domain 20 415 2.8E-110 T 28-03-2018 IPR010071 Amino acid adenylation domain CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 Gene3D G3DSA:3.30.300.30 384 484 5.2E-28 T 28-03-2018 CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 Pfam PF13193 AMP-binding enzyme C-terminal domain 399 473 1.5E-12 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18125 9ef1b0a4a7ebdc9a2918b7b3e024e0b5 484 Gene3D G3DSA:2.30.38.10 301 381 6.7E-24 T 28-03-2018 CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 Gene3D G3DSA:1.10.10.60 2 41 2.1E-11 T 28-03-2018 CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 14 57 3.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 Gene3D G3DSA:1.10.260.40 42 63 4.9E-5 T 28-03-2018 CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 SUPERFAMILY SSF46689 2 76 2.87E-12 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 SUPERFAMILY SSF48498 80 192 6.99E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 5.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 5.5E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS19900 8c307eb29e6bcfdc590762f533ad59cb 203 Gene3D G3DSA:1.10.357.10 64 195 8.6E-16 T 28-03-2018 CNX65_RS10025 47529f87df033c852a8e741e5958d917 403 Gene3D G3DSA:1.10.630.10 27 239 4.5E-11 T 28-03-2018 CNX65_RS10025 47529f87df033c852a8e741e5958d917 403 SUPERFAMILY SSF48264 61 362 1.07E-21 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10025 47529f87df033c852a8e741e5958d917 403 Gene3D G3DSA:1.10.630.10 270 400 5.8E-11 T 28-03-2018 CNX65_RS14790 88b46e53a2444a5d9f91f5df6a613b82 509 Pfam PF04984 Phage tail sheath protein subtilisin-like domain 230 390 3.3E-32 T 28-03-2018 IPR035089 Tail sheath protein, subtilisin-like domain CNX65_RS14790 88b46e53a2444a5d9f91f5df6a613b82 509 Pfam PF17482 Phage tail sheath C-terminal domain 392 498 7.6E-22 T 28-03-2018 IPR020287 Tail sheath protein, C-terminal domain CNX65_RS12215 ba22f02a9b2c921bd6cbd4818153ec58 276 SUPERFAMILY SSF63380 7 131 1.05E-9 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS12215 ba22f02a9b2c921bd6cbd4818153ec58 276 Gene3D G3DSA:2.40.30.10 4 130 2.9E-33 T 28-03-2018 CNX65_RS12215 ba22f02a9b2c921bd6cbd4818153ec58 276 Pfam PF08021 Siderophore-interacting FAD-binding domain 16 130 1.1E-34 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CNX65_RS12215 ba22f02a9b2c921bd6cbd4818153ec58 276 Gene3D G3DSA:3.40.50.80 143 276 1.2E-47 T 28-03-2018 CNX65_RS12215 ba22f02a9b2c921bd6cbd4818153ec58 276 Pfam PF04954 Siderophore-interacting protein 150 263 2.1E-38 T 28-03-2018 IPR007037 Siderophore-interacting protein CNX65_RS26755 fb7d5aca9b11db35b6d6c2a448698e87 327 SUPERFAMILY SSF102114 10 282 4.45E-38 T 28-03-2018 CNX65_RS26755 fb7d5aca9b11db35b6d6c2a448698e87 327 Gene3D G3DSA:3.20.20.70 6 307 1.6E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS26755 fb7d5aca9b11db35b6d6c2a448698e87 327 Pfam PF04055 Radical SAM superfamily 14 149 1.3E-19 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 Gene3D G3DSA:1.10.1330.10 111 160 1.5E-11 T 28-03-2018 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 ProSitePatterns PS00018 EF-hand calcium-binding domain. 103 115 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 ProSitePatterns PS00018 EF-hand calcium-binding domain. 137 149 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 SMART SM00054 128 156 0.1 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 SMART SM00054 94 122 0.77 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 SMART SM00054 9 37 9.4 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 Gene3D G3DSA:1.10.238.10 79 110 5.2E-4 T 28-03-2018 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 Gene3D G3DSA:1.10.238.10 1 78 6.6E-8 T 28-03-2018 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 Pfam PF13202 EF hand 97 118 7.2E-4 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 Pfam PF13202 EF hand 12 31 8.3E-4 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 Pfam PF13202 EF hand 131 151 6.3E-4 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 SUPERFAMILY SSF47473 3 164 1.38E-24 T 28-03-2018 IPR011992 EF-hand domain pair CNX65_RS27140 9ed77ade997acdeb531275c26118b269 173 ProSitePatterns PS00018 EF-hand calcium-binding domain. 18 30 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS10635 f9724da5bafc6094973f315dfd253d24 270 Pfam PF13349 Putative adhesin 16 252 1.2E-7 T 28-03-2018 IPR025164 Putative adhesin CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 SUPERFAMILY SSF51735 2 230 2.14E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 Gene3D G3DSA:3.40.50.720 40 240 3.1E-63 T 28-03-2018 CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 Gene3D G3DSA:3.40.50.720 1 39 5.1E-6 T 28-03-2018 CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 114 122 9.2E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 61 72 9.2E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 153 9.2E-14 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 108 124 3.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 3.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 191 211 3.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 61 72 3.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 153 3.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 172 3.5E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 121 149 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS34735 6eb845d6b8feb144a1bd6645d57f8aa6 242 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 10 229 2.6E-58 T 28-03-2018 CNX65_RS25920 56c39e97341d50f588e03c795b901d1f 530 Gene3D G3DSA:1.25.40.10 258 519 1.5E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS25920 56c39e97341d50f588e03c795b901d1f 530 Pfam PF13560 Helix-turn-helix domain 79 140 9.2E-9 T 28-03-2018 CNX65_RS25920 56c39e97341d50f588e03c795b901d1f 530 Gene3D G3DSA:3.30.1190.10 108 144 8.4E-6 T 28-03-2018 CNX65_RS25920 56c39e97341d50f588e03c795b901d1f 530 SUPERFAMILY SSF48452 293 393 6.16E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS25920 56c39e97341d50f588e03c795b901d1f 530 SUPERFAMILY SSF47413 92 145 3.33E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS25920 56c39e97341d50f588e03c795b901d1f 530 Gene3D G3DSA:1.10.10.60 78 107 1.3E-4 T 28-03-2018 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 Gene3D G3DSA:1.25.40.10 433 544 2.2E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 Gene3D G3DSA:3.40.50.300 12 167 3.4E-18 T 28-03-2018 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 SUPERFAMILY SSF52540 16 283 3.1E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 PRINTS PR00364 Disease resistance protein signature 49 64 1.5E-6 T 28-03-2018 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 PRINTS PR00364 Disease resistance protein signature 216 230 1.5E-6 T 28-03-2018 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 PRINTS PR00364 Disease resistance protein signature 128 142 1.5E-6 T 28-03-2018 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 Gene3D G3DSA:1.10.10.10 270 348 1.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 SMART SM00028 589 622 38.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 SMART SM00028 629 662 12.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 SMART SM00028 549 582 160.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 SMART SM00028 469 502 41.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 SUPERFAMILY SSF48452 465 659 1.83E-16 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 Pfam PF00931 NB-ARC domain 31 228 2.2E-8 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS13755 262fc95939ab1df5d52bb328dc20a3f4 676 Gene3D G3DSA:1.25.40.10 545 676 6.6E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 SUPERFAMILY SSF88659 103 162 4.49E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 Gene3D G3DSA:1.10.10.10 108 210 4.1E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 SUPERFAMILY SSF88946 7 89 2.67E-13 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 Pfam PF08281 Sigma-70, region 4 112 160 4.4E-10 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 22 163 6.9E-14 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 Gene3D G3DSA:1.10.1740.10 3 83 1.1E-13 T 28-03-2018 CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 Pfam PF04542 Sigma-70 region 2 20 79 2.6E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS30495 dae26c71722ee45a754edd16fa273955 407 Gene3D G3DSA:1.25.40.120 211 406 5.9E-4 T 28-03-2018 CNX65_RS29645 52ab25d20af6104629f45a64472bf630 292 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 197 213 - T 28-03-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site CNX65_RS29645 52ab25d20af6104629f45a64472bf630 292 Gene3D G3DSA:3.40.50.720 95 260 1.3E-47 T 28-03-2018 CNX65_RS29645 52ab25d20af6104629f45a64472bf630 292 SUPERFAMILY SSF51735 84 258 1.56E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS29645 52ab25d20af6104629f45a64472bf630 292 Gene3D G3DSA:3.40.50.720 9 94 2.7E-15 T 28-03-2018 CNX65_RS29645 52ab25d20af6104629f45a64472bf630 292 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 91 257 2.8E-44 T 28-03-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 CNX65_RS29645 52ab25d20af6104629f45a64472bf630 292 SUPERFAMILY SSF52283 26 112 1.02E-7 T 28-03-2018 CNX65_RS07510 2dc48cf8112bc32e14b1ade5701027cc 207 Pfam PF12502 Protein of unknown function (DUF3710) 31 198 6.8E-58 T 28-03-2018 IPR022183 Protein of unknown function DUF3710 CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 SUPERFAMILY SSF51735 3 243 4.32E-67 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 71 82 5.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 204 224 5.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 5.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 118 134 5.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 144 163 5.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 165 182 5.5E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 Gene3D G3DSA:3.40.50.720 1 48 2.6E-9 T 28-03-2018 CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 Gene3D G3DSA:3.40.50.720 49 246 9.9E-54 T 28-03-2018 CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 241 8.3E-55 T 28-03-2018 CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 71 82 8.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 144 163 8.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 7 175 0.0018 T 28-03-2018 CNX65_RS02030 c070cb0a696687cafed3aac33fb2e9f7 249 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 131 159 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS34145 000be93cb36bfa186372b8418bb1357b 212 Pfam PF07510 Protein of unknown function (DUF1524) 112 205 2.7E-8 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CNX65_RS30720 3fa348833015a19e17f087fb025a659a 332 Gene3D G3DSA:3.40.50.720 1 131 7.0E-29 T 28-03-2018 CNX65_RS30720 3fa348833015a19e17f087fb025a659a 332 SUPERFAMILY SSF55347 127 273 5.89E-24 T 28-03-2018 CNX65_RS30720 3fa348833015a19e17f087fb025a659a 332 SUPERFAMILY SSF51735 2 154 1.34E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30720 3fa348833015a19e17f087fb025a659a 332 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 1 115 1.9E-16 T 28-03-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 CNX65_RS30720 3fa348833015a19e17f087fb025a659a 332 Gene3D G3DSA:3.30.360.10 132 332 9.7E-40 T 28-03-2018 CNX65_RS30720 3fa348833015a19e17f087fb025a659a 332 Pfam PF02894 Oxidoreductase family, C-terminal alpha/beta domain 132 226 1.3E-11 T 28-03-2018 IPR004104 Oxidoreductase, C-terminal GO:0008152|GO:0016491|GO:0055114 CNX65_RS23260 2ab4185468a070bc70457e6cebb8f988 334 Gene3D G3DSA:2.160.20.10 26 334 2.3E-70 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS23260 2ab4185468a070bc70457e6cebb8f988 334 Pfam PF01095 Pectinesterase 34 326 3.4E-38 T 28-03-2018 IPR000070 Pectinesterase, catalytic GO:0005618|GO:0030599|GO:0042545 KEGG: 00040+3.1.1.11|MetaCyc: PWY-1081|MetaCyc: PWY-7246|MetaCyc: PWY-7248 CNX65_RS23260 2ab4185468a070bc70457e6cebb8f988 334 SUPERFAMILY SSF51126 29 332 6.1E-63 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS30135 afc3fe49ed41755441b9f85bea6a93bf 219 Pfam PF01939 Endonuclease NucS 1 219 4.5E-82 T 28-03-2018 IPR002793 Endonuclease NucS CNX65_RS30135 afc3fe49ed41755441b9f85bea6a93bf 219 Hamap MF_00722 Endonuclease NucS [nucS]. 1 211 31.341 T 28-03-2018 IPR002793 Endonuclease NucS CNX65_RS16055 89b7911a246a68974d58c1f1022660b6 358 PIRSF PIRSF000355 10 358 3.2E-126 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16055 89b7911a246a68974d58c1f1022660b6 358 Pfam PF00268 Ribonucleotide reductase, small chain 38 325 1.3E-84 T 28-03-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 CNX65_RS16055 89b7911a246a68974d58c1f1022660b6 358 SUPERFAMILY SSF47240 20 329 1.05E-94 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS16055 89b7911a246a68974d58c1f1022660b6 358 Gene3D G3DSA:1.10.620.20 14 339 1.3E-97 T 28-03-2018 CNX65_RS32870 41d1d4482d11bd9078beec71c5ba3bca 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 167 191 2.8E-35 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32870 41d1d4482d11bd9078beec71c5ba3bca 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 137 156 2.8E-35 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32870 41d1d4482d11bd9078beec71c5ba3bca 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 244 268 2.8E-35 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32870 41d1d4482d11bd9078beec71c5ba3bca 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 332 351 2.8E-35 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32870 41d1d4482d11bd9078beec71c5ba3bca 520 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 384 410 2.8E-35 T 28-03-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32870 41d1d4482d11bd9078beec71c5ba3bca 520 Pfam PF00361 Proton-conducting membrane transporter 131 425 3.2E-62 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32870 41d1d4482d11bd9078beec71c5ba3bca 520 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 7 508 6.5E-170 T 28-03-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS01545 fa9cb6bd45f55ab859bf9c4b7cb404c5 354 TIGRFAM TIGR03617 F420_MSMEG_2256: probable F420-dependent oxidoreductase, MSMEG_2256 family 53 344 1.5E-134 T 28-03-2018 IPR019919 Luciferase-like, F420-dependent oxidoreductase, MSMEG2256, predicted CNX65_RS01545 fa9cb6bd45f55ab859bf9c4b7cb404c5 354 Gene3D G3DSA:3.20.20.30 39 347 9.9E-60 T 28-03-2018 CNX65_RS01545 fa9cb6bd45f55ab859bf9c4b7cb404c5 354 SUPERFAMILY SSF51679 46 343 8.98E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS01545 fa9cb6bd45f55ab859bf9c4b7cb404c5 354 Pfam PF00296 Luciferase-like monooxygenase 44 339 4.2E-66 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS26975 0e85c5243af969e8755c99208e6ce288 1058 SMART SM00387 568 681 3.3E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26975 0e85c5243af969e8755c99208e6ce288 1058 Gene3D G3DSA:3.30.565.10 489 680 1.9E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26975 0e85c5243af969e8755c99208e6ce288 1058 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 571 678 5.0E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26975 0e85c5243af969e8755c99208e6ce288 1058 SUPERFAMILY SSF55874 554 678 3.27E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26975 0e85c5243af969e8755c99208e6ce288 1058 Pfam PF08376 Nitrate and nitrite sensing 105 340 3.1E-27 T 28-03-2018 IPR013587 Nitrate/nitrite sensing protein CNX65_RS26975 0e85c5243af969e8755c99208e6ce288 1058 Pfam PF00672 HAMP domain 385 452 6.7E-7 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS11935 1d38522f64c52d1815a00b42b8c614fa 439 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 144 353 2.7E-73 T 28-03-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS11935 1d38522f64c52d1815a00b42b8c614fa 439 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 18 433 1.2E-159 T 28-03-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS11935 1d38522f64c52d1815a00b42b8c614fa 439 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 344 353 - T 28-03-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7219 CNX65_RS11935 1d38522f64c52d1815a00b42b8c614fa 439 Gene3D G3DSA:3.40.50.300 58 353 4.7E-81 T 28-03-2018 CNX65_RS11935 1d38522f64c52d1815a00b42b8c614fa 439 SUPERFAMILY SSF52540 91 358 6.36E-93 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11935 1d38522f64c52d1815a00b42b8c614fa 439 SMART SM00382 156 337 2.2E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS04760 1d7ff040ef493113055b50297614c6dc 739 Gene3D G3DSA:1.25.10.10 215 701 2.1E-8 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS04760 1d7ff040ef493113055b50297614c6dc 739 SUPERFAMILY SSF48371 441 609 5.76E-6 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS20125 b196412df62e121bdba0fc0b46230f77 283 Gene3D G3DSA:3.20.20.30 15 279 1.3E-47 T 28-03-2018 CNX65_RS20125 b196412df62e121bdba0fc0b46230f77 283 TIGRFAM TIGR03564 F420_MSMEG_4879: F420-dependent oxidoreductase, MSMEG_4879 family 19 261 9.6E-76 T 28-03-2018 IPR019910 Luciferase-like, F420-dependent oxidoreductase, MSMEG4879, predicted CNX65_RS20125 b196412df62e121bdba0fc0b46230f77 283 Pfam PF00296 Luciferase-like monooxygenase 23 258 2.0E-39 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS20125 b196412df62e121bdba0fc0b46230f77 283 SUPERFAMILY SSF51679 16 276 3.53E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS04600 dd2bea8b5cf20cbab2163b61a7b5abb3 468 SUPERFAMILY SSF55486 55 406 1.76E-112 T 28-03-2018 CNX65_RS04600 dd2bea8b5cf20cbab2163b61a7b5abb3 468 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 56 406 1.1E-115 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CNX65_RS04600 dd2bea8b5cf20cbab2163b61a7b5abb3 468 Gene3D G3DSA:3.40.1190.20 245 431 4.3E-4 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS04600 dd2bea8b5cf20cbab2163b61a7b5abb3 468 Pfam PF10103 Zincin-like metallopeptidase 56 403 1.6E-115 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CNX65_RS02555 3681f846bc5f7d4d7b8477dad7aa39ac 281 Pfam PF01774 UreD urease accessory protein 45 194 7.7E-22 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CNX65_RS02555 3681f846bc5f7d4d7b8477dad7aa39ac 281 Hamap MF_01384 Urease accessory protein UreD [ureD]. 1 247 16.466 T 28-03-2018 IPR002669 Urease accessory protein UreD GO:0006807|GO:0016151 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 SUPERFAMILY SSF47729 1 90 4.71E-32 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 28-03-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 3.5E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 3.5E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 3.5E-17 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.8E-34 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 SMART SM00411 1 90 1.1E-43 T 28-03-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 CNX65_RS04245 041e3009543679ac4ab1dbc687bbd7b0 90 Gene3D G3DSA:4.10.520.10 1 90 1.9E-33 T 28-03-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain GO:0003677 CNX65_RS11895 ccb1127227f22e32869fb356673e95c4 297 PRINTS PR01021 OMPA domain signature 223 239 9.9E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CNX65_RS11895 ccb1127227f22e32869fb356673e95c4 297 PRINTS PR01021 OMPA domain signature 175 197 9.9E-5 T 28-03-2018 IPR006664 Outer membrane protein, bacterial GO:0009279|GO:0016021 CNX65_RS11895 ccb1127227f22e32869fb356673e95c4 297 SUPERFAMILY SSF103088 166 279 4.97E-26 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS11895 ccb1127227f22e32869fb356673e95c4 297 Gene3D G3DSA:3.30.1330.60 109 294 1.2E-36 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS11895 ccb1127227f22e32869fb356673e95c4 297 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 10 63 4.2E-24 T 28-03-2018 IPR025713 Motility protein B, N-terminal domain CNX65_RS11895 ccb1127227f22e32869fb356673e95c4 297 Pfam PF00691 OmpA family 175 272 1.6E-16 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 SUPERFAMILY SSF53697 17 377 3.34E-73 T 28-03-2018 CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 Gene3D G3DSA:3.40.50.10490 324 382 9.6E-12 T 28-03-2018 CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 Gene3D G3DSA:3.40.50.10490 66 198 5.2E-27 T 28-03-2018 CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 Gene3D G3DSA:3.40.50.10490 199 306 2.7E-24 T 28-03-2018 CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 Pfam PF00342 Phosphoglucose isomerase 81 285 1.5E-6 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 189 207 1.2E-6 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 263 284 1.2E-6 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS25805 a8dda3765ee510476a3619f74aea9f6d 539 PRINTS PR00662 Glucose-6-phosphate isomerase signature 85 104 1.2E-6 T 28-03-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS03005 980f52c72876d676fd04bcb6d8df9011 98 Pfam PF00253 Ribosomal protein S14p/S29e 45 97 3.2E-23 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS03005 980f52c72876d676fd04bcb6d8df9011 98 Hamap MF_00537 30S ribosomal protein S14 [rpsN]. 1 98 25.761 T 28-03-2018 IPR023036 Ribosomal protein S14, bacterial/plastid CNX65_RS03005 980f52c72876d676fd04bcb6d8df9011 98 Gene3D G3DSA:4.10.830.10 1 98 4.1E-30 T 28-03-2018 CNX65_RS03005 980f52c72876d676fd04bcb6d8df9011 98 SUPERFAMILY SSF57716 2 98 3.49E-32 T 28-03-2018 CNX65_RS30975 530cb4a5cda27b38200142d5656960fc 84 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 76 18.807 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS30975 530cb4a5cda27b38200142d5656960fc 84 Pfam PF02467 Transcription factor WhiB 3 71 2.6E-27 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS06385 2909677310878ff63b6e1dd7958f9b91 281 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 49 247 8.8E-20 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CNX65_RS17250 bbad4aee644511f77f88fabdf9d24a7a 174 Gene3D G3DSA:3.90.79.10 1 166 1.9E-27 T 28-03-2018 CNX65_RS17250 bbad4aee644511f77f88fabdf9d24a7a 174 PRINTS PR00502 NUDIX hydrolase family signature 56 71 1.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS17250 bbad4aee644511f77f88fabdf9d24a7a 174 PRINTS PR00502 NUDIX hydrolase family signature 42 56 1.7E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS17250 bbad4aee644511f77f88fabdf9d24a7a 174 Pfam PF00293 NUDIX domain 8 150 1.1E-15 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS17250 bbad4aee644511f77f88fabdf9d24a7a 174 SUPERFAMILY SSF55811 6 143 8.39E-22 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS17250 bbad4aee644511f77f88fabdf9d24a7a 174 ProSitePatterns PS00893 Nudix box signature. 47 68 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Gene3D G3DSA:2.30.38.10 442 524 5.4E-14 T 28-03-2018 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Pfam PF00501 AMP-binding enzyme 95 530 9.1E-93 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 30 651 3.0E-293 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Gene3D G3DSA:3.40.50.980 272 437 2.5E-34 T 28-03-2018 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Gene3D G3DSA:3.30.300.30 525 639 3.8E-29 T 28-03-2018 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 ProSitePatterns PS00455 Putative AMP-binding domain signature. 266 277 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 SUPERFAMILY SSF56801 30 650 1.83E-176 T 28-03-2018 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 35 88 3.1E-23 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Gene3D G3DSA:3.40.50.980 81 271 1.9E-52 T 28-03-2018 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Hamap MF_01123 Acetyl-coenzyme A synthetase [acs]. 16 654 51.086 T 28-03-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 CNX65_RS01240 0f704656d9b1e13d34b43876a06089d5 661 Pfam PF13193 AMP-binding enzyme C-terminal domain 539 620 6.8E-27 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS20195 b17c6a35f5f50d35e6a57fbc9c3febdf 373 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 261 267 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CNX65_RS20195 b17c6a35f5f50d35e6a57fbc9c3febdf 373 Gene3D G3DSA:3.20.20.70 16 366 4.9E-94 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS20195 b17c6a35f5f50d35e6a57fbc9c3febdf 373 Pfam PF01070 FMN-dependent dehydrogenase 24 363 5.6E-113 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CNX65_RS20195 b17c6a35f5f50d35e6a57fbc9c3febdf 373 PIRSF PIRSF000138 10 368 9.6E-112 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CNX65_RS20195 b17c6a35f5f50d35e6a57fbc9c3febdf 373 SUPERFAMILY SSF51395 17 363 5.74E-86 T 28-03-2018 CNX65_RS26540 05b413d746a21032ed0d03abf0f4ad5a 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 55 5.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS26540 05b413d746a21032ed0d03abf0f4ad5a 190 Gene3D G3DSA:1.10.10.60 2 63 1.0E-16 T 28-03-2018 CNX65_RS26540 05b413d746a21032ed0d03abf0f4ad5a 190 Gene3D G3DSA:1.10.357.10 64 188 1.1E-17 T 28-03-2018 CNX65_RS26540 05b413d746a21032ed0d03abf0f4ad5a 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 33 56 3.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS26540 05b413d746a21032ed0d03abf0f4ad5a 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 12 25 3.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS26540 05b413d746a21032ed0d03abf0f4ad5a 190 SUPERFAMILY SSF46689 5 75 6.16E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS34500 356d2b87ff090ab73c64dc88de9d3531 340 Pfam PF02780 Transketolase, C-terminal domain 212 330 1.5E-34 T 28-03-2018 IPR033248 Transketolase, C-terminal domain CNX65_RS34500 356d2b87ff090ab73c64dc88de9d3531 340 Gene3D G3DSA:3.40.50.920 210 339 2.8E-31 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS34500 356d2b87ff090ab73c64dc88de9d3531 340 SMART SM00861 20 195 1.2E-70 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS34500 356d2b87ff090ab73c64dc88de9d3531 340 SUPERFAMILY SSF52922 211 336 6.67E-34 T 28-03-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824|GO:0008152 CNX65_RS34500 356d2b87ff090ab73c64dc88de9d3531 340 Pfam PF02779 Transketolase, pyrimidine binding domain 19 194 1.0E-45 T 28-03-2018 IPR005475 Transketolase-like, pyrimidine-binding domain CNX65_RS34500 356d2b87ff090ab73c64dc88de9d3531 340 Gene3D G3DSA:3.40.50.970 16 208 5.0E-60 T 28-03-2018 CNX65_RS34500 356d2b87ff090ab73c64dc88de9d3531 340 SUPERFAMILY SSF52518 19 198 1.51E-67 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS28235 4301282dde12f0e2d371bd6ea79a4b39 240 Pfam PF03799 Cell division protein FtsQ 125 223 3.4E-7 T 28-03-2018 IPR005548 Cell division protein FtsQ/DivIB CNX65_RS28235 4301282dde12f0e2d371bd6ea79a4b39 240 Hamap MF_00911 Cell division protein FtsQ [ftsQ]. 26 240 16.403 T 28-03-2018 IPR026579 Cell division protein FtsQ GO:0090529 CNX65_RS28235 4301282dde12f0e2d371bd6ea79a4b39 240 Pfam PF08478 POTRA domain, FtsQ-type 55 121 5.2E-16 T 28-03-2018 IPR013685 POTRA domain, FtsQ-type CNX65_RS10240 b2779adbbae871b6ce6f8817ab7b822e 196 Pfam PF13671 AAA domain 39 172 4.2E-14 T 28-03-2018 CNX65_RS10240 b2779adbbae871b6ce6f8817ab7b822e 196 PIRSF PIRSF037081 35 195 5.1E-18 T 28-03-2018 IPR017101 P-loop ATP/GTP binding protein, All4644, predicted CNX65_RS10240 b2779adbbae871b6ce6f8817ab7b822e 196 SUPERFAMILY SSF52540 32 154 9.87E-11 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10240 b2779adbbae871b6ce6f8817ab7b822e 196 Gene3D G3DSA:3.40.50.300 30 195 5.9E-10 T 28-03-2018 CNX65_RS26410 033c64edd1e188db22b8f744165ab8ca 240 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 203 234 0.0012 T 28-03-2018 CNX65_RS16665 8e7d9dce2ecdde2f698a3479a2eaa11f 439 SMART SM00530 21 77 5.9E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS16665 8e7d9dce2ecdde2f698a3479a2eaa11f 439 SUPERFAMILY SSF48452 299 401 2.45E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16665 8e7d9dce2ecdde2f698a3479a2eaa11f 439 Gene3D G3DSA:1.10.260.40 9 82 2.2E-11 T 28-03-2018 CNX65_RS16665 8e7d9dce2ecdde2f698a3479a2eaa11f 439 Gene3D G3DSA:1.25.40.10 222 433 8.1E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS16665 8e7d9dce2ecdde2f698a3479a2eaa11f 439 SUPERFAMILY SSF47413 19 79 4.15E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS16665 8e7d9dce2ecdde2f698a3479a2eaa11f 439 Pfam PF13560 Helix-turn-helix domain 18 76 7.1E-12 T 28-03-2018 CNX65_RS05235 fe3706e10856fbc65894a48010c7dd39 125 Gene3D G3DSA:3.10.450.50 11 125 6.6E-16 T 28-03-2018 CNX65_RS05235 fe3706e10856fbc65894a48010c7dd39 125 SUPERFAMILY SSF54427 13 122 1.18E-16 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS05235 fe3706e10856fbc65894a48010c7dd39 125 Pfam PF12680 SnoaL-like domain 16 111 1.0E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS17905 9e3dbbbaa87bd46ba011330b4be4d841 248 SMART SM00346 10 99 1.6E-13 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS17905 9e3dbbbaa87bd46ba011330b4be4d841 248 SUPERFAMILY SSF46785 13 80 6.48E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17905 9e3dbbbaa87bd46ba011330b4be4d841 248 Pfam PF09339 IclR helix-turn-helix domain 14 62 7.1E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS17905 9e3dbbbaa87bd46ba011330b4be4d841 248 Gene3D G3DSA:1.10.10.10 5 70 3.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17905 9e3dbbbaa87bd46ba011330b4be4d841 248 SUPERFAMILY SSF55781 74 247 2.29E-44 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS17905 9e3dbbbaa87bd46ba011330b4be4d841 248 Pfam PF01614 Bacterial transcriptional regulator 127 227 8.5E-27 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS17905 9e3dbbbaa87bd46ba011330b4be4d841 248 Gene3D G3DSA:3.30.450.40 75 248 4.3E-48 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS05095 e73e51486a463fc7a3f631cd9c303143 270 Gene3D G3DSA:3.60.15.10 1 265 2.3E-47 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05095 e73e51486a463fc7a3f631cd9c303143 270 Pfam PF12706 Beta-lactamase superfamily domain 49 224 2.8E-18 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05095 e73e51486a463fc7a3f631cd9c303143 270 SMART SM00849 18 194 0.0071 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05095 e73e51486a463fc7a3f631cd9c303143 270 SUPERFAMILY SSF56281 3 255 3.79E-50 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS27670 5f54590658aeba7fb35f91737130b383 113 Pfam PF11774 Lsr2 2 110 7.1E-40 T 28-03-2018 IPR024412 Lsr2 CNX65_RS27670 5f54590658aeba7fb35f91737130b383 113 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 107 1.0E-20 T 28-03-2018 IPR024412 Lsr2 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 12 296 54.785 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 16 292 1.7E-77 T 28-03-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 3.3E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 46 67 3.3E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 82 100 3.3E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 PRINTS PR00146 Dihydrodipicolinate synthase signature 114 130 3.3E-26 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 49 66 - T 28-03-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 SUPERFAMILY SSF51569 12 294 8.9E-91 T 28-03-2018 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 SMART SM01130 12 295 8.9E-116 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 144 174 - T 28-03-2018 IPR020625 Schiff base-forming aldolase, active site GO:0008152|GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 Gene3D G3DSA:3.20.20.70 9 295 2.4E-91 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 PIRSF PIRSF001365 10 298 6.8E-82 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS28460 b688980198e45333100ed85878a7a6a5 298 Pfam PF00701 Dihydrodipicolinate synthetase family 13 294 2.5E-79 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS13440 9ba781660f04263756938a19e30b76fd 266 Pfam PF01261 Xylose isomerase-like TIM barrel 31 192 4.7E-20 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS13440 9ba781660f04263756938a19e30b76fd 266 Gene3D G3DSA:3.20.20.150 1 264 1.9E-32 T 28-03-2018 CNX65_RS13440 9ba781660f04263756938a19e30b76fd 266 SUPERFAMILY SSF51658 10 263 2.49E-29 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS11450 e4acca185abf94aaf58f9117d7ba7c87 321 PIRSF PIRSF016838 1 321 1.5E-121 T 28-03-2018 IPR028349 Protein PafC CNX65_RS11450 e4acca185abf94aaf58f9117d7ba7c87 321 Gene3D G3DSA:1.10.10.10 2 57 1.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11450 e4acca185abf94aaf58f9117d7ba7c87 321 Pfam PF13280 WYL domain 147 314 5.8E-32 T 28-03-2018 IPR026881 WYL domain CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 TIGRFAM TIGR02407 ectoine_ectB: diaminobutyrate--2-oxoglutarate aminotransferase 6 411 5.5E-187 T 28-03-2018 IPR012773 Ectoine biosynthetic protein GO:0019491|GO:0030170|GO:0047307 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 267 - T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 TIGRFAM TIGR00709 dat: 2,4-diaminobutyrate 4-transaminase 6 413 3.9E-130 T 28-03-2018 IPR004637 2,4-diaminobutyrate 4-transaminase GO:0008483|GO:0009058 KEGG: 00260+2.6.1.76|MetaCyc: PWY-6409|MetaCyc: PWY-6562|MetaCyc: PWY-761|MetaCyc: PWY-7855 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 Gene3D G3DSA:3.90.1150.10 302 414 3.7E-24 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 SUPERFAMILY SSF53383 9 410 7.11E-106 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 Pfam PF00202 Aminotransferase class-III 15 409 8.9E-76 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 PIRSF PIRSF000521 181 413 1.2E-31 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 PIRSF PIRSF000521 120 158 0.055 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 PIRSF PIRSF000521 3 126 1.4E-5 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 Gene3D G3DSA:3.40.640.10 180 301 1.1E-29 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS21035 ba15f591057ea51e3fad3bad6ed51bcc 415 Gene3D G3DSA:3.90.1150.10 1 158 7.8E-35 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS21665 73c5676d4178982fb07a8b72fa2db68b 134 Gene3D G3DSA:1.20.120.20 2 131 5.1E-8 T 28-03-2018 CNX65_RS29635 19c14a9693a8c2052469f7041b99ec05 301 Pfam PF07681 DoxX 148 231 1.4E-16 T 28-03-2018 IPR032808 DoxX family CNX65_RS03720 bd0299cc8fe701b3728e117d1ce475dc 239 SMART SM00862 148 223 2.4E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS03720 bd0299cc8fe701b3728e117d1ce475dc 239 Pfam PF00072 Response regulator receiver domain 5 114 4.8E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS03720 bd0299cc8fe701b3728e117d1ce475dc 239 Gene3D G3DSA:1.10.10.10 124 230 3.9E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03720 bd0299cc8fe701b3728e117d1ce475dc 239 Gene3D G3DSA:3.40.50.2300 1 123 1.2E-36 T 28-03-2018 CNX65_RS03720 bd0299cc8fe701b3728e117d1ce475dc 239 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 222 1.7E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS03720 bd0299cc8fe701b3728e117d1ce475dc 239 SUPERFAMILY SSF52172 3 171 9.11E-39 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS03720 bd0299cc8fe701b3728e117d1ce475dc 239 SMART SM00448 3 114 1.6E-38 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS33430 c1030d5381e1d57a83c5917f96927cce 225 Pfam PF00005 ABC transporter 21 168 1.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS33430 c1030d5381e1d57a83c5917f96927cce 225 SUPERFAMILY SSF52540 4 222 3.47E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS33430 c1030d5381e1d57a83c5917f96927cce 225 Gene3D G3DSA:3.40.50.300 1 225 1.6E-58 T 28-03-2018 CNX65_RS33430 c1030d5381e1d57a83c5917f96927cce 225 SMART SM00382 29 217 6.9E-20 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS23290 bac3d7f036e40809edf66d8eb8516ac4 287 Pfam PF00296 Luciferase-like monooxygenase 5 246 3.8E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS23290 bac3d7f036e40809edf66d8eb8516ac4 287 SUPERFAMILY SSF51679 5 283 3.01E-58 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS23290 bac3d7f036e40809edf66d8eb8516ac4 287 Gene3D G3DSA:3.20.20.30 1 286 2.7E-59 T 28-03-2018 CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 407 417 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 205 216 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 Gene3D G3DSA:3.40.50.200 161 472 7.3E-85 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 Pfam PF00082 Subtilase family 200 456 4.2E-53 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 SUPERFAMILY SSF52743 182 466 4.06E-77 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 PRINTS PR00723 Subtilisin serine protease family (S8) signature 200 219 2.1E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 PRINTS PR00723 Subtilisin serine protease family (S8) signature 406 422 2.1E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS07715 00ed808d0557c7e40b137c1f6ed06e40 1058 PRINTS PR00723 Subtilisin serine protease family (S8) signature 237 250 2.1E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS04445 7889f4d0d39420fc23e5a2885a8604f0 521 Gene3D G3DSA:3.40.50.1820 89 513 2.9E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04445 7889f4d0d39420fc23e5a2885a8604f0 521 Pfam PF00561 alpha/beta hydrolase fold 110 497 5.7E-52 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS04445 7889f4d0d39420fc23e5a2885a8604f0 521 SUPERFAMILY SSF53474 396 499 8.11E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04445 7889f4d0d39420fc23e5a2885a8604f0 521 SUPERFAMILY SSF53474 205 334 8.11E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04445 7889f4d0d39420fc23e5a2885a8604f0 521 SUPERFAMILY SSF53474 95 159 8.11E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27285 39805b0c415df25247305a210d55fed4 249 SUPERFAMILY SSF46785 3 72 6.83E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27285 39805b0c415df25247305a210d55fed4 249 Pfam PF09339 IclR helix-turn-helix domain 4 53 2.7E-10 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS27285 39805b0c415df25247305a210d55fed4 249 SMART SM00346 2 89 1.7E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS27285 39805b0c415df25247305a210d55fed4 249 Pfam PF01614 Bacterial transcriptional regulator 117 240 8.7E-35 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS27285 39805b0c415df25247305a210d55fed4 249 Gene3D G3DSA:1.10.10.10 1 60 4.6E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27285 39805b0c415df25247305a210d55fed4 249 Gene3D G3DSA:3.30.450.40 65 245 2.9E-48 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS27285 39805b0c415df25247305a210d55fed4 249 SUPERFAMILY SSF55781 57 245 2.45E-49 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS22630 ac23a5d6f3bb53484237e389bebe6be4 119 Gene3D G3DSA:2.60.120.10 10 119 6.2E-8 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS22630 ac23a5d6f3bb53484237e389bebe6be4 119 SUPERFAMILY SSF51182 16 117 1.89E-8 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 Gene3D G3DSA:3.50.50.60 9 157 7.3E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 337 4.4E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 SUPERFAMILY SSF51905 6 346 2.31E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 Gene3D G3DSA:3.40.50.720 161 394 1.8E-32 T 28-03-2018 CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 11 30 5.9E-11 T 28-03-2018 CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 168 186 5.9E-11 T 28-03-2018 CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 289 311 5.9E-11 T 28-03-2018 CNX65_RS03425 3ca44d11ce3c45674318ea22f4321359 441 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 108 126 5.9E-11 T 28-03-2018 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 SMART SM00065 25 166 7.6E-11 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 SMART SM00388 171 239 8.4E-18 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 Pfam PF01590 GAF domain 26 155 9.3E-7 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 Pfam PF00512 His Kinase A (phospho-acceptor) domain 172 239 1.8E-15 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 283 389 3.2E-23 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 SUPERFAMILY SSF55874 228 389 9.95E-47 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 SUPERFAMILY SSF55781 27 156 1.74E-23 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 SMART SM00387 283 391 1.9E-33 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 SUPERFAMILY SSF47384 157 240 2.16E-19 T 28-03-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 Gene3D G3DSA:3.30.565.10 234 391 3.3E-44 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 320 334 4.6E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 388 4.6E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 338 348 4.6E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 PRINTS PR00344 Bacterial sensor protein C-terminal signature 351 369 4.6E-19 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 Gene3D G3DSA:3.30.450.40 4 168 5.3E-21 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS11250 ea1cf4b2fcce232104c16ff99ccd5f8c 399 Gene3D G3DSA:1.10.287.130 169 233 6.1E-17 T 28-03-2018 CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 Gene3D G3DSA:3.40.50.1100 19 207 2.0E-45 T 28-03-2018 CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 SUPERFAMILY SSF53686 13 399 3.01E-144 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 Gene3D G3DSA:3.40.50.1100 208 410 3.1E-41 T 28-03-2018 CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 91 105 - T 28-03-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 62 388 2.0E-49 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 PIRSF PIRSF001413 3 406 5.7E-156 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 12 401 50.679 T 28-03-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS27945 cc77aa5079ec68d3a874ee07d3604c03 411 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 17 397 7.7E-181 T 28-03-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 CNX65_RS33365 d26b716fcba4815d29dab224cc4407dc 254 Pfam PF13411 MerR HTH family regulatory protein 4 70 1.6E-17 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS33365 d26b716fcba4815d29dab224cc4407dc 254 Gene3D G3DSA:1.10.1660.10 1 140 2.1E-32 T 28-03-2018 CNX65_RS33365 d26b716fcba4815d29dab224cc4407dc 254 SUPERFAMILY SSF89082 165 250 8.5E-17 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CNX65_RS33365 d26b716fcba4815d29dab224cc4407dc 254 Gene3D G3DSA:1.10.490.50 163 252 1.6E-19 T 28-03-2018 CNX65_RS33365 d26b716fcba4815d29dab224cc4407dc 254 Pfam PF07739 TipAS antibiotic-recognition domain 131 248 2.8E-26 T 28-03-2018 IPR012925 TipAS antibiotic-recognition domain CNX65_RS33365 d26b716fcba4815d29dab224cc4407dc 254 SUPERFAMILY SSF46955 3 111 2.38E-26 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS33365 d26b716fcba4815d29dab224cc4407dc 254 SMART SM00422 3 72 1.9E-22 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS24735 78c5527d20ae5dff49656bf585c42211 366 Gene3D G3DSA:3.90.180.10 1 195 1.7E-55 T 28-03-2018 CNX65_RS24735 78c5527d20ae5dff49656bf585c42211 366 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 152 2.5E-24 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS24735 78c5527d20ae5dff49656bf585c42211 366 SUPERFAMILY SSF51735 159 330 2.2E-44 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24735 78c5527d20ae5dff49656bf585c42211 366 Gene3D G3DSA:3.40.50.720 196 313 2.2E-22 T 28-03-2018 CNX65_RS24735 78c5527d20ae5dff49656bf585c42211 366 Pfam PF00107 Zinc-binding dehydrogenase 197 313 1.1E-27 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS24735 78c5527d20ae5dff49656bf585c42211 366 SUPERFAMILY SSF50129 2 193 5.63E-58 T 28-03-2018 IPR011032 GroES-like CNX65_RS24735 78c5527d20ae5dff49656bf585c42211 366 SMART SM00829 12 365 9.2E-4 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 SUPERFAMILY SSF48498 76 187 1.38E-9 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 ProSitePatterns PS01081 TetR-type HTH domain signature. 22 52 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 54 7.6E-18 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 1.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 1.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 Gene3D G3DSA:1.10.357.10 57 190 6.1E-15 T 28-03-2018 CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 SUPERFAMILY SSF46689 3 76 3.9E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS03280 523c77f0ad2501382343dcc03a6ba158 198 Gene3D G3DSA:1.10.10.60 2 56 5.7E-21 T 28-03-2018 CNX65_RS32505 267efddeb067116d314fb7d7af54eef7 286 Pfam PF01636 Phosphotransferase enzyme family 99 224 7.3E-8 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS32505 267efddeb067116d314fb7d7af54eef7 286 SUPERFAMILY SSF56112 24 245 1.87E-19 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS32505 267efddeb067116d314fb7d7af54eef7 286 Gene3D G3DSA:3.90.1200.10 93 272 4.7E-17 T 28-03-2018 CNX65_RS23500 b434b1d0a6cd345c71f0f07e19550966 461 SUPERFAMILY SSF53720 8 453 6.28E-78 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS23500 b434b1d0a6cd345c71f0f07e19550966 461 Gene3D G3DSA:3.40.309.10 238 410 7.3E-19 T 28-03-2018 CNX65_RS23500 b434b1d0a6cd345c71f0f07e19550966 461 Gene3D G3DSA:3.40.605.10 4 237 3.0E-42 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS23500 b434b1d0a6cd345c71f0f07e19550966 461 Pfam PF00171 Aldehyde dehydrogenase family 7 274 1.1E-32 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS07765 67ccd263e0691340041c6d08928754c2 310 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 14 213 2.3E-43 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CNX65_RS20040 9cc72ff5369389ca32f945eaf04f7872 291 Gene3D G3DSA:2.120.10.30 14 291 6.2E-26 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS20040 9cc72ff5369389ca32f945eaf04f7872 291 SUPERFAMILY SSF63829 17 287 7.19E-31 T 28-03-2018 CNX65_RS12265 140d7a5819065d2eeb3a04d074034f43 325 Gene3D G3DSA:3.40.109.10 107 323 3.6E-21 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS12265 140d7a5819065d2eeb3a04d074034f43 325 SUPERFAMILY SSF55469 226 322 3.82E-13 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS12265 140d7a5819065d2eeb3a04d074034f43 325 SUPERFAMILY SSF55469 5 67 3.82E-13 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS12265 140d7a5819065d2eeb3a04d074034f43 325 Gene3D G3DSA:3.40.109.10 1 106 7.2E-12 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS00630 979462dbd2b8010aedebea6b01153190 128 Pfam PF04138 GtrA-like protein 2 125 1.5E-16 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 SUPERFAMILY SSF109854 5 141 1.37E-19 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 Pfam PF12867 DinB superfamily 14 145 2.5E-26 T 28-03-2018 IPR024775 DinB-like domain CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 Gene3D G3DSA:3.90.1580.10 166 440 1.3E-71 T 28-03-2018 CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 Pfam PF03781 Sulfatase-modifying factor enzyme 1 172 429 5.5E-65 T 28-03-2018 IPR005532 Sulfatase-modifying factor enzyme Reactome: R-HSA-1660662|Reactome: R-HSA-1663150 CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 SUPERFAMILY SSF56436 169 431 5.84E-78 T 28-03-2018 IPR016187 C-type lectin fold CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 TIGRFAM TIGR03440 egtB_TIGR03440: ergothioneine biosynthesis protein EgtB 12 428 7.2E-133 T 28-03-2018 IPR017806 Ergothioneine biosynthesis protein EgtB GO:0052699 CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 Hamap MF_02035 Hercynine oxygenase [egtB]. 1 431 51.658 T 28-03-2018 IPR032890 Hercynine oxygenase, Actinobacteria GO:0016491|GO:0052699 CNX65_RS10820 78c53b442fadddea9e7aefff2e4f030b 442 Gene3D G3DSA:1.20.120.450 1 156 6.3E-19 T 28-03-2018 CNX65_RS21535 de13b880c29c95acdbaa0504f3ff584e 486 SUPERFAMILY SSF55904 340 483 6.15E-32 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CNX65_RS21535 de13b880c29c95acdbaa0504f3ff584e 486 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 416 469 2.4E-11 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CNX65_RS21535 de13b880c29c95acdbaa0504f3ff584e 486 Gene3D G3DSA:3.90.1150.10 308 385 1.3E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS21535 de13b880c29c95acdbaa0504f3ff584e 486 Gene3D G3DSA:3.40.640.10 6 284 8.9E-42 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS21535 de13b880c29c95acdbaa0504f3ff584e 486 Gene3D G3DSA:3.90.100.10 386 485 3.5E-28 T 28-03-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 CNX65_RS21535 de13b880c29c95acdbaa0504f3ff584e 486 SUPERFAMILY SSF53383 7 381 4.59E-69 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS21535 de13b880c29c95acdbaa0504f3ff584e 486 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 7 300 2.6E-52 T 28-03-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 CNX65_RS16595 bcf16e2837f1c8c3535484b171fecaf7 68 Pfam PF01361 Tautomerase enzyme 2 62 6.4E-20 T 28-03-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 CNX65_RS16595 bcf16e2837f1c8c3535484b171fecaf7 68 SUPERFAMILY SSF55331 2 62 5.64E-13 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CNX65_RS16595 bcf16e2837f1c8c3535484b171fecaf7 68 Gene3D G3DSA:3.30.429.10 1 63 1.4E-20 T 28-03-2018 CNX65_RS30425 cc897868d98bb47a3c91411a9b4f8200 287 Pfam PF13377 Periplasmic binding protein-like domain 126 282 3.5E-29 T 28-03-2018 CNX65_RS30425 cc897868d98bb47a3c91411a9b4f8200 287 Gene3D G3DSA:3.40.50.2300 11 123 1.9E-22 T 28-03-2018 CNX65_RS30425 cc897868d98bb47a3c91411a9b4f8200 287 Gene3D G3DSA:3.40.50.2300 124 285 3.6E-40 T 28-03-2018 CNX65_RS30425 cc897868d98bb47a3c91411a9b4f8200 287 SUPERFAMILY SSF53822 13 267 2.94E-53 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS08520 0f95b834d828f535322ed0500a41af05 125 SUPERFAMILY SSF54427 6 118 4.05E-7 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS08520 0f95b834d828f535322ed0500a41af05 125 Gene3D G3DSA:3.10.450.50 6 122 4.0E-8 T 28-03-2018 CNX65_RS33630 cc215a991f21c7e8493e62e6cb7d4ce2 484 Gene3D G3DSA:1.10.260.40 45 119 3.1E-7 T 28-03-2018 CNX65_RS33630 cc215a991f21c7e8493e62e6cb7d4ce2 484 SUPERFAMILY SSF47413 59 119 2.34E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS33630 cc215a991f21c7e8493e62e6cb7d4ce2 484 Gene3D G3DSA:1.25.40.10 275 467 4.4E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 269 311 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 SUPERFAMILY SSF46689 220 266 7.77E-9 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 SMART SM00342 232 315 2.0E-26 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 SUPERFAMILY SSF52317 3 198 3.35E-50 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 Gene3D G3DSA:1.10.10.60 272 322 9.3E-13 T 28-03-2018 CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 Pfam PF01965 DJ-1/PfpI family 4 177 5.5E-21 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 Gene3D G3DSA:3.40.50.880 1 234 5.1E-67 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 SUPERFAMILY SSF46689 269 319 1.08E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 Pfam PF12833 Helix-turn-helix domain 238 316 2.5E-21 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS05320 6e7d19e136b5a3384391c55449da1947 322 Gene3D G3DSA:1.10.10.60 235 271 1.5E-12 T 28-03-2018 CNX65_RS15250 c1f66c6aaac1ba12d09b9315fbffa7dd 342 Gene3D G3DSA:3.40.50.10140 138 290 6.5E-12 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS15250 c1f66c6aaac1ba12d09b9315fbffa7dd 342 Pfam PF13676 TIR domain 143 247 9.0E-13 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS15250 c1f66c6aaac1ba12d09b9315fbffa7dd 342 SUPERFAMILY SSF52200 137 264 1.83E-8 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS18650 fa570bbbe16d1550a32a6782ab30f63f 354 Pfam PF04443 Acyl-protein synthetase, LuxE 81 349 1.3E-6 T 28-03-2018 IPR007534 Acyl-protein synthetase, LuxE GO:0008218|GO:0047474 MetaCyc: PWY-7723 CNX65_RS08325 7f4b178e7b8f874d2391baed5f372a8f 231 Pfam PF00005 ABC transporter 19 160 1.8E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS08325 7f4b178e7b8f874d2391baed5f372a8f 231 SUPERFAMILY SSF52540 2 222 3.04E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08325 7f4b178e7b8f874d2391baed5f372a8f 231 Gene3D G3DSA:3.40.50.300 1 228 6.0E-56 T 28-03-2018 CNX65_RS08325 7f4b178e7b8f874d2391baed5f372a8f 231 TIGRFAM TIGR03410 urea_trans_UrtE: urea ABC transporter, ATP-binding protein UrtE 2 231 9.6E-91 T 28-03-2018 IPR017780 ABC transporter, urea, ATP-binding protein, UrtE CNX65_RS08325 7f4b178e7b8f874d2391baed5f372a8f 231 SMART SM00382 26 209 2.7E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS33550 e775528db8d8bcb6cd8cf11cd0e92955 1611 Pfam PF12458 ATPase involved in DNA repair 24 479 7.3E-189 T 28-03-2018 IPR020958 DUF3686 CNX65_RS33550 e775528db8d8bcb6cd8cf11cd0e92955 1611 Gene3D G3DSA:3.40.50.300 1167 1436 9.0E-11 T 28-03-2018 CNX65_RS33550 e775528db8d8bcb6cd8cf11cd0e92955 1611 Pfam PF07728 AAA domain (dynein-related subfamily) 1252 1378 9.7E-5 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CNX65_RS33550 e775528db8d8bcb6cd8cf11cd0e92955 1611 SUPERFAMILY SSF52540 1247 1397 8.07E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34100 96bee819b5ce03e73ccdc0b8e36b0f19 436 SUPERFAMILY SSF140459 33 183 8.11E-5 T 28-03-2018 CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 SMART SM01091 358 436 7.0E-27 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 Gene3D G3DSA:3.30.465.10 352 436 3.5E-29 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 SUPERFAMILY SSF54631 212 353 2.02E-27 T 28-03-2018 CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 SUPERFAMILY SSF56176 357 439 1.66E-23 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 Gene3D G3DSA:3.10.580.10 203 351 3.9E-29 T 28-03-2018 CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 Pfam PF00571 CBS domain 292 342 2.7E-4 T 28-03-2018 IPR000644 CBS domain CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 Pfam PF01595 Domain of unknown function DUF21 13 205 3.0E-30 T 28-03-2018 IPR002550 Domain of unknown function DUF21 CNX65_RS26605 1f6894f5a6572df38e991f19ecfb2ca7 444 Pfam PF03471 Transporter associated domain 360 435 7.3E-24 T 28-03-2018 IPR005170 Transporter-associated domain CNX65_RS20575 72d3425a30731572513eaa2761195733 432 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 123 403 6.2E-19 T 28-03-2018 IPR020801 Polyketide synthase, acyl transferase domain CNX65_RS20575 72d3425a30731572513eaa2761195733 432 Gene3D G3DSA:3.40.366.10 9 234 7.6E-12 T 28-03-2018 CNX65_RS20575 72d3425a30731572513eaa2761195733 432 Pfam PF00698 Acyl transferase domain 155 359 4.4E-22 T 28-03-2018 IPR014043 Acyl transferase CNX65_RS20575 72d3425a30731572513eaa2761195733 432 Gene3D G3DSA:3.40.366.10 272 392 2.7E-22 T 28-03-2018 CNX65_RS20575 72d3425a30731572513eaa2761195733 432 SUPERFAMILY SSF55048 223 285 2.88E-9 T 28-03-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding GO:0003824|GO:0008152 CNX65_RS20575 72d3425a30731572513eaa2761195733 432 SUPERFAMILY SSF52151 287 388 3.92E-38 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20575 72d3425a30731572513eaa2761195733 432 SUPERFAMILY SSF52151 119 224 3.92E-38 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS20575 72d3425a30731572513eaa2761195733 432 Gene3D G3DSA:3.30.70.250 235 271 4.7E-13 T 28-03-2018 CNX65_RS20520 b02b5f90b2a03217377a34db9f40a735 208 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 65 107 3.7E-8 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS20520 b02b5f90b2a03217377a34db9f40a735 208 SUPERFAMILY SSF69118 7 181 3.77E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS20520 b02b5f90b2a03217377a34db9f40a735 208 Gene3D G3DSA:1.20.1290.10 66 191 2.2E-23 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS20520 b02b5f90b2a03217377a34db9f40a735 208 Gene3D G3DSA:1.20.5.810 16 61 7.2E-9 T 28-03-2018 CNX65_RS20520 b02b5f90b2a03217377a34db9f40a735 208 Pfam PF02627 Carboxymuconolactone decarboxylase family 48 109 4.5E-7 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS06295 cdfd62fb8ee2aeaf2ccdcf8a02faddf0 127 SUPERFAMILY SSF54909 3 63 3.72E-12 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS06295 cdfd62fb8ee2aeaf2ccdcf8a02faddf0 127 Gene3D G3DSA:3.30.70.100 1 116 4.5E-14 T 28-03-2018 CNX65_RS06295 cdfd62fb8ee2aeaf2ccdcf8a02faddf0 127 Pfam PF03992 Antibiotic biosynthesis monooxygenase 4 63 1.4E-11 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CNX65_RS23460 c48eb7ba409d52c03f1cdf40afd4400f 453 Pfam PF00557 Metallopeptidase family M24 192 430 3.4E-45 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS23460 c48eb7ba409d52c03f1cdf40afd4400f 453 Gene3D G3DSA:3.40.350.10 35 196 1.6E-25 T 28-03-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal CNX65_RS23460 c48eb7ba409d52c03f1cdf40afd4400f 453 SMART SM01011 44 185 6.8E-22 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CNX65_RS23460 c48eb7ba409d52c03f1cdf40afd4400f 453 Pfam PF05195 Aminopeptidase P, N-terminal domain 50 171 6.9E-16 T 28-03-2018 IPR007865 Aminopeptidase P, N-terminal GO:0004177|GO:0030145 CNX65_RS23460 c48eb7ba409d52c03f1cdf40afd4400f 453 Gene3D G3DSA:3.90.230.10 197 453 3.5E-60 T 28-03-2018 CNX65_RS23460 c48eb7ba409d52c03f1cdf40afd4400f 453 SUPERFAMILY SSF55920 185 450 3.01E-59 T 28-03-2018 IPR000994 Peptidase M24 CNX65_RS23460 c48eb7ba409d52c03f1cdf40afd4400f 453 SUPERFAMILY SSF53092 50 182 1.94E-18 T 28-03-2018 IPR028980 Creatinase/Aminopeptidase P, N-terminal CNX65_RS32860 84cf6f12e66f99d65dc50a2dee12fc49 333 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 215 227 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CNX65_RS32860 84cf6f12e66f99d65dc50a2dee12fc49 333 SUPERFAMILY SSF48576 21 332 2.88E-80 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS32860 84cf6f12e66f99d65dc50a2dee12fc49 333 Pfam PF00348 Polyprenyl synthetase 46 284 3.3E-59 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CNX65_RS32860 84cf6f12e66f99d65dc50a2dee12fc49 333 Gene3D G3DSA:1.10.600.10 9 333 5.4E-95 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS19720 c14f26e3cbf4a5dd7c2db792e433a2eb 113 Gene3D G3DSA:1.10.10.10 1 110 7.5E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19720 c14f26e3cbf4a5dd7c2db792e433a2eb 113 Pfam PF12840 Helix-turn-helix domain 9 66 1.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19720 c14f26e3cbf4a5dd7c2db792e433a2eb 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 43 58 3.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19720 c14f26e3cbf4a5dd7c2db792e433a2eb 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 11 26 3.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19720 c14f26e3cbf4a5dd7c2db792e433a2eb 113 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 58 73 3.4E-12 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS19720 c14f26e3cbf4a5dd7c2db792e433a2eb 113 SUPERFAMILY SSF46785 6 100 6.96E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19720 c14f26e3cbf4a5dd7c2db792e433a2eb 113 SMART SM00418 9 83 1.7E-18 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS13825 1109a9263817d1d663033fb5501210c8 379 Gene3D G3DSA:3.60.120.10 40 376 3.6E-92 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS13825 1109a9263817d1d663033fb5501210c8 379 Pfam PF00425 chorismate binding enzyme 104 365 3.4E-67 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CNX65_RS13825 1109a9263817d1d663033fb5501210c8 379 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 99 373 4.3E-75 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CNX65_RS13825 1109a9263817d1d663033fb5501210c8 379 SUPERFAMILY SSF56322 85 374 9.55E-86 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS04740 dea019e1070445cc05fb6ed36b8ca69e 325 Gene3D G3DSA:3.60.40.10 64 320 2.6E-19 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS04740 dea019e1070445cc05fb6ed36b8ca69e 325 Pfam PF13672 Protein phosphatase 2C 75 278 7.9E-24 T 28-03-2018 CNX65_RS04740 dea019e1070445cc05fb6ed36b8ca69e 325 SUPERFAMILY SSF81606 75 319 8.5E-14 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS26590 2db237be9f030724146f99a857ee4484 350 Gene3D G3DSA:3.40.710.10 13 316 4.2E-27 T 28-03-2018 CNX65_RS26590 2db237be9f030724146f99a857ee4484 350 Pfam PF13354 Beta-lactamase enzyme family 91 287 5.1E-38 T 28-03-2018 CNX65_RS26590 2db237be9f030724146f99a857ee4484 350 SUPERFAMILY SSF56601 88 309 2.06E-28 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS02345 78f123c9041a3b8c53e95f192d7bad15 594 Gene3D G3DSA:1.20.120.20 304 535 1.8E-7 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Gene3D G3DSA:2.60.40.1120 509 600 1.7E-12 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 SUPERFAMILY SSF117074 931 1005 1.03E-14 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Pfam PF13620 Carboxypeptidase regulatory-like domain 614 667 7.0E-9 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Pfam PF13620 Carboxypeptidase regulatory-like domain 515 575 1.2E-8 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Gene3D G3DSA:2.60.40.10 707 811 1.7E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Gene3D G3DSA:2.60.40.10 929 1018 3.4E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Gene3D G3DSA:2.60.40.10 394 506 4.2E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Gene3D G3DSA:2.60.40.10 1023 1140 3.6E-16 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Gene3D G3DSA:2.60.40.10 815 885 1.0E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 SUPERFAMILY SSF117074 1021 1096 1.83E-14 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 SUPERFAMILY SSF117074 804 895 3.01E-14 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 SUPERFAMILY SSF49478 515 586 3.41E-11 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 SUPERFAMILY SSF49464 614 699 1.53E-10 T 28-03-2018 IPR008969 Carboxypeptidase-like, regulatory domain CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Pfam PF17210 SdrD B-like domain 819 882 1.1E-9 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Pfam PF17210 SdrD B-like domain 932 1004 1.6E-10 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Pfam PF17210 SdrD B-like domain 711 785 1.5E-13 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Pfam PF17210 SdrD B-like domain 1026 1093 5.0E-14 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Pfam PF17210 SdrD B-like domain 401 480 2.1E-9 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 Gene3D G3DSA:2.60.40.10 608 688 6.1E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 SUPERFAMILY SSF117074 703 779 3.27E-14 T 28-03-2018 CNX65_RS19115 25b57e540a2d727c92d36e78b8e92996 1225 SUPERFAMILY SSF117074 394 476 1.23E-10 T 28-03-2018 CNX65_RS14040 c5be29151ccf6f603c50aebe5134004f 183 Pfam PF13527 Acetyltransferase (GNAT) domain 8 139 1.4E-7 T 28-03-2018 CNX65_RS14040 c5be29151ccf6f603c50aebe5134004f 183 SUPERFAMILY SSF55729 8 168 7.98E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS14040 c5be29151ccf6f603c50aebe5134004f 183 Gene3D G3DSA:3.40.630.30 2 172 1.2E-21 T 28-03-2018 CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 Pfam PF00271 Helicase conserved C-terminal domain 241 349 1.1E-28 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 Gene3D G3DSA:3.40.50.300 230 494 1.9E-45 T 28-03-2018 CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 Pfam PF03880 DbpA RNA binding domain 484 555 3.4E-25 T 28-03-2018 IPR005580 DEAD box helicase DbpA/CsdA, RNA-binding domain CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 160 168 - T 28-03-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 SUPERFAMILY SSF52540 82 370 6.05E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 SMART SM00487 29 232 2.4E-63 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 SMART SM00490 268 349 3.4E-33 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 Gene3D G3DSA:3.40.50.300 2 229 9.2E-63 T 28-03-2018 CNX65_RS11535 7e6cbaa30ac28f600ff98a7ce15cb44a 561 Pfam PF00270 DEAD/DEAH box helicase 34 202 1.1E-49 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS23485 f52a084a8649833c3739193d728667c5 318 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 132 314 5.1E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS23485 f52a084a8649833c3739193d728667c5 318 SUPERFAMILY SSF161098 109 300 4.71E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS23485 f52a084a8649833c3739193d728667c5 318 Gene3D G3DSA:1.10.3720.10 28 307 7.1E-46 T 28-03-2018 CNX65_RS04660 ad321dec41ffcd5f00f44d09e329338d 161 SUPERFAMILY SSF74982 4 133 2.75E-52 T 28-03-2018 IPR023620 Small protein B CNX65_RS04660 ad321dec41ffcd5f00f44d09e329338d 161 Gene3D G3DSA:2.40.280.10 10 128 4.6E-50 T 28-03-2018 IPR023620 Small protein B CNX65_RS04660 ad321dec41ffcd5f00f44d09e329338d 161 ProSitePatterns PS01317 SsrA-binding protein. 28 40 - T 28-03-2018 IPR020081 SsrA-binding protein, conserved site CNX65_RS04660 ad321dec41ffcd5f00f44d09e329338d 161 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 10 133 5.0E-51 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CNX65_RS04660 ad321dec41ffcd5f00f44d09e329338d 161 Pfam PF01668 SmpB protein 10 149 2.4E-60 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CNX65_RS04660 ad321dec41ffcd5f00f44d09e329338d 161 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 2.3E-57 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CNX65_RS04660 ad321dec41ffcd5f00f44d09e329338d 161 Hamap MF_00023 SsrA-binding protein [smpB]. 1 156 71.884 T 28-03-2018 IPR000037 SsrA-binding protein GO:0003723 CNX65_RS28905 3237183ad92b9d8596716baeb0d791bf 88 Pfam PF04226 Transglycosylase associated protein 33 83 8.5E-11 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 88 3.0E-9 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 SUPERFAMILY SSF50129 1 142 2.13E-35 T 28-03-2018 IPR011032 GroES-like CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 Pfam PF00107 Zinc-binding dehydrogenase 149 264 2.8E-33 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 138 159 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 Gene3D G3DSA:3.90.180.10 1 132 6.7E-41 T 28-03-2018 CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 SMART SM00829 10 320 2.2E-47 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 SUPERFAMILY SSF51735 109 267 4.24E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13365 3f33ab0e2129d0d5968fbce12123ffdb 322 Gene3D G3DSA:3.40.50.720 133 306 1.3E-40 T 28-03-2018 CNX65_RS19395 a4b7012ed16eaa1235788eb1677e9fcf 435 SUPERFAMILY SSF51905 351 407 7.25E-5 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19395 a4b7012ed16eaa1235788eb1677e9fcf 435 Pfam PF01636 Phosphotransferase enzyme family 99 299 2.2E-12 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS19395 a4b7012ed16eaa1235788eb1677e9fcf 435 Gene3D G3DSA:3.90.1200.10 134 317 1.4E-16 T 28-03-2018 CNX65_RS19395 a4b7012ed16eaa1235788eb1677e9fcf 435 Gene3D G3DSA:3.40.50.720 346 430 2.3E-4 T 28-03-2018 CNX65_RS19395 a4b7012ed16eaa1235788eb1677e9fcf 435 SUPERFAMILY SSF56112 104 306 4.37E-13 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS14690 c74ddb86a87c211b06a3a5c3db77da20 370 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 216 289 9.6E-17 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS06310 fd9aeff966d39711dce9258ce4efdb8b 211 SMART SM00947 26 186 2.9E-54 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS06310 fd9aeff966d39711dce9258ce4efdb8b 211 ProSitePatterns PS00704 Prokaryotic-type carbonic anhydrases signature 1. 38 45 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS06310 fd9aeff966d39711dce9258ce4efdb8b 211 ProSitePatterns PS00705 Prokaryotic-type carbonic anhydrases signature 2. 82 102 - T 28-03-2018 IPR015892 Carbonic anhydrase, prokaryotic-like, conserved site GO:0004089|GO:0008270|GO:0015976 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS06310 fd9aeff966d39711dce9258ce4efdb8b 211 Pfam PF00484 Carbonic anhydrase 34 181 2.4E-40 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS06310 fd9aeff966d39711dce9258ce4efdb8b 211 Gene3D G3DSA:3.40.1050.10 2 206 4.0E-52 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS06310 fd9aeff966d39711dce9258ce4efdb8b 211 SUPERFAMILY SSF53056 18 186 8.24E-49 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS31160 ad07032ce09bbe46eb985776337c32b0 321 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 3 313 1.9E-121 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CNX65_RS31160 ad07032ce09bbe46eb985776337c32b0 321 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 321 135.936 T 28-03-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 CNX65_RS31160 ad07032ce09bbe46eb985776337c32b0 321 Gene3D G3DSA:1.10.8.240 39 113 2.3E-37 T 28-03-2018 CNX65_RS31160 ad07032ce09bbe46eb985776337c32b0 321 Gene3D G3DSA:3.40.50.10680 114 320 7.0E-46 T 28-03-2018 CNX65_RS31160 ad07032ce09bbe46eb985776337c32b0 321 Pfam PF01933 Uncharacterised protein family UPF0052 3 282 2.1E-66 T 28-03-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 CNX65_RS31160 ad07032ce09bbe46eb985776337c32b0 321 SUPERFAMILY SSF142338 3 316 1.44E-83 T 28-03-2018 CNX65_RS03655 6283b947d975a7d1b1dab8b68aff1f9e 164 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 134 140 - T 28-03-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS03655 6283b947d975a7d1b1dab8b68aff1f9e 164 Gene3D G3DSA:1.10.10.10 80 164 3.5E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03655 6283b947d975a7d1b1dab8b68aff1f9e 164 SUPERFAMILY SSF46767 85 164 5.49E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS03655 6283b947d975a7d1b1dab8b68aff1f9e 164 Gene3D G3DSA:3.30.160.70 1 79 5.3E-5 T 28-03-2018 CNX65_RS03655 6283b947d975a7d1b1dab8b68aff1f9e 164 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 85 163 1.3E-26 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS03655 6283b947d975a7d1b1dab8b68aff1f9e 164 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 85 164 3.2E-25 T 28-03-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 CNX65_RS28220 4359d8db719bb54db8730b87b6b7b080 231 PIRSF PIRSF004848 1 231 3.4E-59 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CNX65_RS28220 4359d8db719bb54db8730b87b6b7b080 231 SUPERFAMILY SSF51419 4 224 6.73E-62 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS28220 4359d8db719bb54db8730b87b6b7b080 231 Gene3D G3DSA:3.20.20.10 1 230 9.6E-61 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS28220 4359d8db719bb54db8730b87b6b7b080 231 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 8 226 5.2E-40 T 28-03-2018 IPR011078 Pyridoxal phosphate homeostasis protein CNX65_RS28220 4359d8db719bb54db8730b87b6b7b080 231 Pfam PF01168 Alanine racemase, N-terminal domain 10 226 1.5E-18 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS25220 7e56bb1d34cb5fdafc309f986f52cac8 267 Gene3D G3DSA:2.60.120.200 21 262 1.9E-26 T 28-03-2018 CNX65_RS25220 7e56bb1d34cb5fdafc309f986f52cac8 267 SUPERFAMILY SSF49899 24 245 4.03E-20 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS25220 7e56bb1d34cb5fdafc309f986f52cac8 267 Pfam PF00722 Glycosyl hydrolases family 16 123 226 1.1E-7 T 28-03-2018 IPR000757 Glycoside hydrolase family 16 GO:0004553|GO:0005975 CNX65_RS14300 2ac076e8fc0578c3e407a4d473a8f09c 256 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 68 242 2.6E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14300 2ac076e8fc0578c3e407a4d473a8f09c 256 SUPERFAMILY SSF161098 3 256 3.16E-63 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14300 2ac076e8fc0578c3e407a4d473a8f09c 256 Gene3D G3DSA:1.10.3720.10 1 247 4.4E-38 T 28-03-2018 CNX65_RS16910 3a986dd9e178744f6b1631c662bdb0b5 710 SUPERFAMILY SSF51905 5 186 1.46E-6 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS16910 3a986dd9e178744f6b1631c662bdb0b5 710 Gene3D G3DSA:3.50.50.60 4 408 7.2E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS16910 3a986dd9e178744f6b1631c662bdb0b5 710 Pfam PF13454 FAD-NAD(P)-binding 2 164 1.5E-18 T 28-03-2018 CNX65_RS19730 bc8e694a71f10501f5f0e4fce46e0831 400 Gene3D G3DSA:1.20.1250.20 17 203 2.6E-6 T 28-03-2018 CNX65_RS19730 bc8e694a71f10501f5f0e4fce46e0831 400 SUPERFAMILY SSF103473 16 389 3.01E-15 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19730 bc8e694a71f10501f5f0e4fce46e0831 400 Gene3D G3DSA:1.20.1250.20 211 391 0.099 T 28-03-2018 CNX65_RS32555 b4df8ab501874551fcda04742c754d7e 365 Pfam PF00005 ABC transporter 21 168 7.7E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS32555 b4df8ab501874551fcda04742c754d7e 365 Gene3D G3DSA:3.40.50.300 1 284 2.4E-56 T 28-03-2018 CNX65_RS32555 b4df8ab501874551fcda04742c754d7e 365 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS32555 b4df8ab501874551fcda04742c754d7e 365 SMART SM00382 29 225 2.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS32555 b4df8ab501874551fcda04742c754d7e 365 SUPERFAMILY SSF52540 7 231 3.67E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 Gene3D G3DSA:3.10.25.10 208 310 1.0E-26 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 2 303 5.2E-64 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 Pfam PF02911 Formyl transferase, C-terminal domain 204 301 8.6E-21 T 28-03-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 SUPERFAMILY SSF50486 206 308 3.73E-25 T 28-03-2018 IPR011034 Formyl transferase, C-terminal-like GO:0003824 CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 Gene3D G3DSA:3.40.50.170 1 206 3.7E-57 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 SUPERFAMILY SSF53328 2 204 7.98E-53 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 Pfam PF00551 Formyl transferase 18 180 7.0E-31 T 28-03-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 CNX65_RS25995 572a0e822d36b4cc41f4d6a9b04ea8c0 310 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 304 30.632 T 28-03-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 CNX65_RS06470 29ab0ad62d58c7c2183c8ab4e4d706f5 114 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 3 114 18.59 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CNX65_RS06470 29ab0ad62d58c7c2183c8ab4e4d706f5 114 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 4 109 2.8E-25 T 28-03-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 CNX65_RS06860 1c53be400959ff7083f59fa8c15e79e3 144 Pfam PF10604 Polyketide cyclase / dehydrase and lipid transport 5 141 9.7E-16 T 28-03-2018 IPR019587 Polyketide cyclase/dehydrase CNX65_RS06860 1c53be400959ff7083f59fa8c15e79e3 144 Gene3D G3DSA:3.30.530.20 3 143 7.4E-26 T 28-03-2018 IPR023393 START-like domain CNX65_RS06860 1c53be400959ff7083f59fa8c15e79e3 144 SUPERFAMILY SSF55961 4 142 3.3E-28 T 28-03-2018 CNX65_RS28205 58e35b9f4ac517d381ff6b663827d7f3 273 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 39 6.1E-15 T 28-03-2018 IPR019933 DivIVA domain CNX65_RS28205 58e35b9f4ac517d381ff6b663827d7f3 273 Pfam PF05103 DivIVA protein 3 65 2.2E-12 T 28-03-2018 IPR007793 DivIVA family CNX65_RS28205 58e35b9f4ac517d381ff6b663827d7f3 273 Gene3D G3DSA:1.20.5.170 30 70 3.3E-4 T 28-03-2018 CNX65_RS28205 58e35b9f4ac517d381ff6b663827d7f3 273 Gene3D G3DSA:1.20.5.620 131 155 7.7E-5 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS28205 58e35b9f4ac517d381ff6b663827d7f3 273 Gene3D G3DSA:1.20.5.620 156 212 3.2E-7 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS27320 69622ac14e7d05c8940f7566e34d4cc3 394 Pfam PF01757 Acyltransferase family 8 316 2.5E-16 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 SUPERFAMILY SSF53474 420 669 1.07E-65 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 Pfam PF00326 Prolyl oligopeptidase family 464 669 1.3E-47 T 28-03-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 SUPERFAMILY SSF82171 21 143 8.76E-31 T 28-03-2018 CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 SUPERFAMILY SSF82171 173 399 8.76E-31 T 28-03-2018 CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 Pfam PF07676 WD40-like Beta Propeller Repeat 64 94 0.089 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 Gene3D G3DSA:3.40.50.1820 415 676 1.7E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 Gene3D G3DSA:2.140.10.30 3 137 5.5E-11 T 28-03-2018 CNX65_RS07245 2d1e2fdb67cf78af6cf87b8f7380f158 680 Gene3D G3DSA:2.140.10.30 138 404 2.6E-22 T 28-03-2018 CNX65_RS30535 866aab5e45f29a6daaa164a585ef6e9c 239 SMART SM00332 1 234 2.6E-21 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS30535 866aab5e45f29a6daaa164a585ef6e9c 239 SUPERFAMILY SSF81606 4 237 3.01E-61 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS30535 866aab5e45f29a6daaa164a585ef6e9c 239 SMART SM00331 10 236 1.1E-24 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS30535 866aab5e45f29a6daaa164a585ef6e9c 239 Gene3D G3DSA:3.60.40.10 4 236 9.8E-41 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS30535 866aab5e45f29a6daaa164a585ef6e9c 239 Pfam PF13672 Protein phosphatase 2C 9 194 9.3E-12 T 28-03-2018 CNX65_RS04140 9ab6fd846d81354f7b9c71e01a9e1d5a 112 SUPERFAMILY SSF50022 7 111 9.37E-32 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS04140 9ab6fd846d81354f7b9c71e01a9e1d5a 112 Gene3D G3DSA:2.102.10.10 5 111 1.3E-17 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS04140 9ab6fd846d81354f7b9c71e01a9e1d5a 112 TIGRFAM TIGR02378 nirD_assim_sml: nitrite reductase [NAD(P)H], small subunit 8 109 1.4E-28 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CNX65_RS04140 9ab6fd846d81354f7b9c71e01a9e1d5a 112 Pfam PF13806 Rieske-like [2Fe-2S] domain 8 109 2.5E-33 T 28-03-2018 IPR012748 Nitrite reductase [NAD(P)H] small subunit, NirD GO:0008942|GO:0042128|GO:0055114 CNX65_RS19285 226a7590cc4e26f41ca9563af7506589 568 TIGRFAM TIGR03882 cyclo_dehyd_2: bacteriocin biosynthesis cyclodehydratase domain 25 179 4.8E-13 T 28-03-2018 IPR022291 Bacteriocin biosynthesis, cyclodehydratase domain CNX65_RS19285 226a7590cc4e26f41ca9563af7506589 568 Pfam PF02624 YcaO cyclodehydratase, ATP-ad Mg2+-binding 205 538 3.3E-71 T 28-03-2018 IPR003776 YcaO-like domain CNX65_RS15300 b49685fa307e86185228f576714b6304 279 SUPERFAMILY SSF53335 8 240 4.45E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS15300 b49685fa307e86185228f576714b6304 279 Pfam PF13649 Methyltransferase domain 42 136 6.8E-20 T 28-03-2018 CNX65_RS15300 b49685fa307e86185228f576714b6304 279 Gene3D G3DSA:3.40.50.150 4 279 3.9E-44 T 28-03-2018 CNX65_RS32190 11ff66ff5f3419b12f085ea1fb91b24a 270 SUPERFAMILY SSF53474 31 248 3.85E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS32190 11ff66ff5f3419b12f085ea1fb91b24a 270 Pfam PF12740 Chlorophyllase enzyme 32 135 7.8E-9 T 28-03-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 CNX65_RS32190 11ff66ff5f3419b12f085ea1fb91b24a 270 Gene3D G3DSA:3.40.50.1820 2 260 2.7E-31 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19145 4624c93ae8bee7d900cc1372f86c06f5 511 Gene3D G3DSA:3.40.50.980 163 322 7.3E-19 T 28-03-2018 CNX65_RS19145 4624c93ae8bee7d900cc1372f86c06f5 511 SUPERFAMILY SSF56801 3 499 1.44E-65 T 28-03-2018 CNX65_RS19145 4624c93ae8bee7d900cc1372f86c06f5 511 Gene3D G3DSA:2.30.38.10 331 407 6.0E-15 T 28-03-2018 CNX65_RS19145 4624c93ae8bee7d900cc1372f86c06f5 511 Pfam PF00501 AMP-binding enzyme 6 408 3.2E-49 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS19145 4624c93ae8bee7d900cc1372f86c06f5 511 Gene3D G3DSA:3.40.50.980 1 162 3.8E-25 T 28-03-2018 CNX65_RS19145 4624c93ae8bee7d900cc1372f86c06f5 511 ProSitePatterns PS00455 Putative AMP-binding domain signature. 157 168 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS08750 bc2c03a9faec8769ba8781e5a31cc66f 261 Gene3D G3DSA:1.10.12.10 216 261 1.1E-4 T 28-03-2018 IPR014748 Crontonase, C-terminal CNX65_RS08750 bc2c03a9faec8769ba8781e5a31cc66f 261 Pfam PF00378 Enoyl-CoA hydratase/isomerase 12 248 3.0E-30 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS08750 bc2c03a9faec8769ba8781e5a31cc66f 261 SUPERFAMILY SSF52096 4 256 9.95E-54 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS08750 bc2c03a9faec8769ba8781e5a31cc66f 261 Gene3D G3DSA:3.90.226.10 6 215 4.4E-44 T 28-03-2018 CNX65_RS07820 e69d738ae05de51a9c4cc5e0777e791b 514 SUPERFAMILY SSF53474 120 168 1.14E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07820 e69d738ae05de51a9c4cc5e0777e791b 514 SUPERFAMILY SSF53474 379 487 1.14E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07820 e69d738ae05de51a9c4cc5e0777e791b 514 SUPERFAMILY SSF53474 210 264 1.14E-19 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07820 e69d738ae05de51a9c4cc5e0777e791b 514 Pfam PF08386 TAP-like protein 414 512 1.7E-20 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS07820 e69d738ae05de51a9c4cc5e0777e791b 514 Gene3D G3DSA:3.40.50.1820 104 502 8.3E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS05650 a9ffb594d45884c555604359629bbb6d 127 Pfam PF01152 Bacterial-like globin 6 119 6.9E-35 T 28-03-2018 IPR001486 Truncated hemoglobin GO:0019825 CNX65_RS05650 a9ffb594d45884c555604359629bbb6d 127 Gene3D G3DSA:1.10.490.10 1 126 3.7E-34 T 28-03-2018 CNX65_RS05650 a9ffb594d45884c555604359629bbb6d 127 ProSitePatterns PS01213 Protozoan/cyanobacterial globins signature. 53 77 - T 28-03-2018 IPR019795 Globin, bacterial-like, conserved site GO:0015671|GO:0019825 CNX65_RS05650 a9ffb594d45884c555604359629bbb6d 127 SUPERFAMILY SSF46458 7 124 1.6E-35 T 28-03-2018 IPR009050 Globin-like CNX65_RS31665 4edf06dfb49fda885ba1e270d40a2fb9 171 SUPERFAMILY SSF82607 8 93 3.66E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS31665 4edf06dfb49fda885ba1e270d40a2fb9 171 Pfam PF02575 YbaB/EbfC DNA-binding family 13 97 8.8E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS31665 4edf06dfb49fda885ba1e270d40a2fb9 171 Gene3D G3DSA:3.30.1310.10 2 102 7.7E-19 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 SUPERFAMILY SSF103473 266 438 1.31E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 SUPERFAMILY SSF103473 504 529 1.31E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 SUPERFAMILY SSF103473 12 213 1.31E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 PRINTS PR01035 Tetracycline resistance protein signature 150 172 3.4E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 PRINTS PR01035 Tetracycline resistance protein signature 120 141 3.4E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 PRINTS PR01035 Tetracycline resistance protein signature 27 43 3.4E-6 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 Pfam PF07690 Major Facilitator Superfamily 30 429 8.9E-51 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 26 528 1.6E-78 T 28-03-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0006810|GO:0016021 CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 Gene3D G3DSA:1.20.1250.20 277 546 3.1E-32 T 28-03-2018 CNX65_RS01575 bc585a390beeaf4c2c003ee2b9e0c335 555 Gene3D G3DSA:1.20.1250.20 15 218 1.5E-31 T 28-03-2018 CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 SMART SM00448 2 112 1.8E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 148 224 2.0E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 Gene3D G3DSA:3.40.50.2300 1 123 4.9E-36 T 28-03-2018 CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 SMART SM00862 148 224 7.3E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 Gene3D G3DSA:1.10.10.10 124 226 4.0E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 SUPERFAMILY SSF46894 127 225 8.5E-32 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 Pfam PF00072 Response regulator receiver domain 4 113 3.4E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS33265 1b7416a4b7b4b863603f8ac9ee586978 226 SUPERFAMILY SSF52172 3 126 6.26E-41 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS25435 f5cd8a0e94a2ab699a07e7c635a47552 152 Gene3D G3DSA:3.40.30.10 1 150 6.2E-36 T 28-03-2018 CNX65_RS25435 f5cd8a0e94a2ab699a07e7c635a47552 152 Pfam PF00578 AhpC/TSA family 4 125 9.1E-31 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS25435 f5cd8a0e94a2ab699a07e7c635a47552 152 SUPERFAMILY SSF52833 2 148 3.47E-41 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS25435 f5cd8a0e94a2ab699a07e7c635a47552 152 PIRSF PIRSF000239 1 148 1.7E-17 T 28-03-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS17490 503286a79a6122c7797549e502566cae 324 Pfam PF00589 Phage integrase family 123 299 2.8E-18 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS17490 503286a79a6122c7797549e502566cae 324 Gene3D G3DSA:1.10.443.10 119 308 8.5E-33 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS17490 503286a79a6122c7797549e502566cae 324 SUPERFAMILY SSF56349 8 306 6.77E-36 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS17490 503286a79a6122c7797549e502566cae 324 Gene3D G3DSA:1.10.150.130 1 116 7.2E-14 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS01605 3efe4ba24053a7bf479516083c6e2dbf 564 Pfam PF00092 von Willebrand factor type A domain 362 544 1.4E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01605 3efe4ba24053a7bf479516083c6e2dbf 564 SMART SM00327 357 560 2.3E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01605 3efe4ba24053a7bf479516083c6e2dbf 564 Gene3D G3DSA:3.40.190.10 141 365 0.0016 T 28-03-2018 CNX65_RS01605 3efe4ba24053a7bf479516083c6e2dbf 564 SUPERFAMILY SSF53850 107 352 1.3E-9 T 28-03-2018 CNX65_RS01605 3efe4ba24053a7bf479516083c6e2dbf 564 Gene3D G3DSA:3.40.50.410 366 558 1.5E-25 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01605 3efe4ba24053a7bf479516083c6e2dbf 564 SUPERFAMILY SSF53300 361 548 3.34E-19 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01605 3efe4ba24053a7bf479516083c6e2dbf 564 Pfam PF13531 Bacterial extracellular solute-binding protein 49 311 3.0E-34 T 28-03-2018 CNX65_RS17830 3688316a430819321dfad05b3d661428 249 Pfam PF13714 Phosphoenolpyruvate phosphomutase 18 243 2.5E-70 T 28-03-2018 CNX65_RS17830 3688316a430819321dfad05b3d661428 249 Gene3D G3DSA:3.20.20.60 8 249 2.1E-55 T 28-03-2018 CNX65_RS17830 3688316a430819321dfad05b3d661428 249 SUPERFAMILY SSF51621 15 247 6.73E-58 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS18690 82c789a2816ed1822e294ac7cd88e848 271 SUPERFAMILY SSF56747 5 160 2.35E-31 T 28-03-2018 CNX65_RS18690 82c789a2816ed1822e294ac7cd88e848 271 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 7 153 5.7E-42 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS18690 82c789a2816ed1822e294ac7cd88e848 271 SMART SM00943 7 154 2.9E-45 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 314 329 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 87 98 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 267 278 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 151 166 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 286 313 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 335 344 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 344 355 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 185 207 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00359 B-class P450 signature 134 150 1.1E-60 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 SUPERFAMILY SSF48264 18 395 6.16E-92 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 Pfam PF00067 Cytochrome P450 173 365 5.7E-23 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 Gene3D G3DSA:1.10.630.10 1 395 8.9E-76 T 28-03-2018 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 337 346 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00385 P450 superfamily signature 267 278 1.2E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00385 P450 superfamily signature 232 249 1.2E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00385 P450 superfamily signature 344 355 1.2E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13635 383556ab970eb39240a6d3f7603e8c58 395 PRINTS PR00385 P450 superfamily signature 335 344 1.2E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 157 324 1.2E-34 T 28-03-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 ProSitePatterns PS00068 Malate dehydrogenase active site signature. 156 168 - T 28-03-2018 IPR001252 Malate dehydrogenase, active site GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383|Reactome: R-HSA-70263 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 TIGRFAM TIGR01759 MalateDH-SF1: malate dehydrogenase 4 323 6.3E-149 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 SUPERFAMILY SSF51735 4 156 1.12E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 148 4.2E-31 T 28-03-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 Gene3D G3DSA:3.40.50.720 7 156 1.8E-25 T 28-03-2018 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 PIRSF PIRSF000102 2 327 7.6E-63 T 28-03-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 SUPERFAMILY SSF56327 157 325 1.7E-62 T 28-03-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 Hamap MF_01517 Malate dehydrogenase [mdh]. 2 327 57.402 T 28-03-2018 IPR010945 Malate dehydrogenase, type 2 GO:0006108|GO:0016615|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 CNX65_RS31855 79f45cb353b114de58b19f3709d0c0eb 329 Gene3D G3DSA:3.90.110.10 157 325 2.1E-55 T 28-03-2018 CNX65_RS31550 98a75e778e6b8c47174094e76b567dde 207 SUPERFAMILY SSF53271 3 205 2.49E-59 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS31550 98a75e778e6b8c47174094e76b567dde 207 Gene3D G3DSA:3.40.50.2020 1 205 8.7E-61 T 28-03-2018 CNX65_RS31550 98a75e778e6b8c47174094e76b567dde 207 Pfam PF14681 Uracil phosphoribosyltransferase 5 206 2.5E-60 T 28-03-2018 CNX65_RS31550 98a75e778e6b8c47174094e76b567dde 207 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 2 207 39.648 T 28-03-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CNX65_RS31550 98a75e778e6b8c47174094e76b567dde 207 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 205 3.1E-72 T 28-03-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 CNX65_RS06150 a1951b0d01e1dad56af129e8dddfe9b3 352 TIGRFAM TIGR01728 SsuA_fam: ABC transporter, substrate-binding protein, aliphatic sulfonates family 38 329 4.1E-56 T 28-03-2018 IPR010067 Aliphatic sulfonates-binding protein GO:0016020|GO:0042626 CNX65_RS06150 a1951b0d01e1dad56af129e8dddfe9b3 352 SUPERFAMILY SSF53850 37 265 3.06E-36 T 28-03-2018 CNX65_RS06150 a1951b0d01e1dad56af129e8dddfe9b3 352 Gene3D G3DSA:3.40.190.10 141 330 6.1E-29 T 28-03-2018 CNX65_RS06150 a1951b0d01e1dad56af129e8dddfe9b3 352 Pfam PF13379 NMT1-like family 34 267 7.2E-34 T 28-03-2018 CNX65_RS06150 a1951b0d01e1dad56af129e8dddfe9b3 352 Gene3D G3DSA:3.40.190.10 33 140 2.1E-13 T 28-03-2018 CNX65_RS01540 fe3fd39312e2aa82f22cf362420d7fb7 289 SMART SM00382 32 224 5.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01540 fe3fd39312e2aa82f22cf362420d7fb7 289 SUPERFAMILY SSF52540 8 238 5.11E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01540 fe3fd39312e2aa82f22cf362420d7fb7 289 Pfam PF00005 ABC transporter 24 175 6.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS01540 fe3fd39312e2aa82f22cf362420d7fb7 289 Gene3D G3DSA:3.40.50.300 5 274 7.3E-51 T 28-03-2018 CNX65_RS01540 fe3fd39312e2aa82f22cf362420d7fb7 289 ProSitePatterns PS00211 ABC transporters family signature. 147 161 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS26945 f31330d124005dd93f6a2742dc66fa8a 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 193 206 1.9E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS26945 f31330d124005dd93f6a2742dc66fa8a 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 358 374 1.9E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS26945 f31330d124005dd93f6a2742dc66fa8a 404 PRINTS PR00723 Subtilisin serine protease family (S8) signature 146 165 1.9E-11 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS26945 f31330d124005dd93f6a2742dc66fa8a 404 Pfam PF00082 Subtilase family 146 379 2.2E-15 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS26945 f31330d124005dd93f6a2742dc66fa8a 404 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 359 369 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS26945 f31330d124005dd93f6a2742dc66fa8a 404 SUPERFAMILY SSF52743 143 400 2.88E-41 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS26945 f31330d124005dd93f6a2742dc66fa8a 404 Gene3D G3DSA:3.40.50.200 112 400 2.5E-37 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS22610 f221a339e47f67f6f2f9a4f93e6f4316 105 Pfam PF02467 Transcription factor WhiB 47 91 7.1E-11 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 SUPERFAMILY SSF54427 186 300 3.14E-13 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 SUPERFAMILY SSF88946 17 99 6.28E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 20 172 8.1E-17 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 Gene3D G3DSA:1.10.1740.10 12 87 8.4E-17 T 28-03-2018 CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 Pfam PF04542 Sigma-70 region 2 21 86 2.2E-15 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 SUPERFAMILY SSF88659 120 173 2.83E-11 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 Gene3D G3DSA:3.10.450.50 166 302 2.5E-18 T 28-03-2018 CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 Gene3D G3DSA:1.10.10.10 88 165 2.5E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06340 5cedb6767e78c35f1aea0d6f7c4fbf98 324 Pfam PF08281 Sigma-70, region 4 122 172 2.5E-12 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS19125 51f06f05f5edc0f8394459520b18711d 366 Gene3D G3DSA:3.80.10.10 89 243 3.2E-6 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CNX65_RS08845 c3b3f6947cec634a59913b53c15f5394 312 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 70 297 1.8E-53 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS08845 c3b3f6947cec634a59913b53c15f5394 312 Gene3D G3DSA:3.40.190.10 41 184 2.3E-30 T 28-03-2018 CNX65_RS08845 c3b3f6947cec634a59913b53c15f5394 312 SUPERFAMILY SSF53850 6 22 1.37E-50 T 28-03-2018 CNX65_RS08845 c3b3f6947cec634a59913b53c15f5394 312 SUPERFAMILY SSF53850 59 297 1.37E-50 T 28-03-2018 CNX65_RS08845 c3b3f6947cec634a59913b53c15f5394 312 SMART SM00062 69 301 1.3E-39 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS08845 c3b3f6947cec634a59913b53c15f5394 312 Gene3D G3DSA:3.40.190.10 185 310 2.2E-10 T 28-03-2018 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 Pfam PF01019 Gamma-glutamyltranspeptidase 68 594 3.9E-147 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 75 100 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 477 492 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 501 518 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 276 292 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 167 186 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 417 435 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 306 325 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 441 459 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 PRINTS PR01210 Gamma-glutamyltranspeptidase signature 149 167 3.3E-67 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 TIGRFAM TIGR00066 g_glut_trans: gamma-glutamyltransferase 55 590 6.7E-122 T 28-03-2018 IPR000101 Gamma-glutamyltranspeptidase GO:0006751|GO:0036374 KEGG: 00430+2.3.2.2|KEGG: 00460+2.3.2.2|KEGG: 00480+2.3.2.2+3.4.19.13|MetaCyc: PWY-4041|MetaCyc: PWY-5826 CNX65_RS26040 5bb390679df325ed9edd3a9f592893ef 605 SUPERFAMILY SSF56235 44 598 7.56E-150 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS11925 edaa9c16008c14e93cb20709e59af23d 326 Gene3D G3DSA:1.10.530.10 164 324 5.8E-44 T 28-03-2018 CNX65_RS11925 edaa9c16008c14e93cb20709e59af23d 326 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 222 250 - T 28-03-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 CNX65_RS11925 edaa9c16008c14e93cb20709e59af23d 326 SUPERFAMILY SSF53955 191 322 1.51E-42 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS11925 edaa9c16008c14e93cb20709e59af23d 326 Pfam PF01464 Transglycosylase SLT domain 204 309 9.8E-28 T 28-03-2018 IPR008258 Transglycosylase SLT domain 1 CNX65_RS11925 edaa9c16008c14e93cb20709e59af23d 326 Gene3D G3DSA:3.90.1720.10 53 163 1.2E-34 T 28-03-2018 CNX65_RS11925 edaa9c16008c14e93cb20709e59af23d 326 Pfam PF00877 NlpC/P60 family 74 162 4.0E-23 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CNX65_RS11925 edaa9c16008c14e93cb20709e59af23d 326 SUPERFAMILY SSF54001 58 173 4.46E-38 T 28-03-2018 CNX65_RS01550 d80e3183ca6351d6cbd441501eeb5700 180 SMART SM00894 144 180 7.2E-20 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CNX65_RS01550 d80e3183ca6351d6cbd441501eeb5700 180 Pfam PF05901 Excalibur calcium-binding domain 145 180 5.4E-15 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CNX65_RS27465 e04404225f0f43e3825631b487bb8388 322 Pfam PF12730 ABC-2 family transporter protein 67 223 5.2E-9 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CNX65_RS28370 286cb2f86b36a32de1d8e56a41c9ed96 278 Gene3D G3DSA:3.40.50.300 1 267 2.9E-54 T 28-03-2018 CNX65_RS28370 286cb2f86b36a32de1d8e56a41c9ed96 278 SUPERFAMILY SSF52540 2 248 1.73E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28370 286cb2f86b36a32de1d8e56a41c9ed96 278 Pfam PF13614 AAA domain 3 173 1.6E-31 T 28-03-2018 IPR025669 AAA domain CNX65_RS02020 8abfd3b339968eae78d8f48e3e205eab 284 SUPERFAMILY SSF56529 62 282 2.49E-75 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS02020 8abfd3b339968eae78d8f48e3e205eab 284 Gene3D G3DSA:3.90.850.10 29 284 2.6E-77 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS02020 8abfd3b339968eae78d8f48e3e205eab 284 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 74 281 1.5E-67 T 28-03-2018 IPR011234 Fumarylacetoacetase, C-terminal-related GO:0003824|GO:0008152 CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 Gene3D G3DSA:3.40.50.300 2 369 1.0E-25 T 28-03-2018 CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 371 97.099 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 SUPERFAMILY SSF52540 3 218 8.11E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 SUPERFAMILY SSF52540 247 335 8.11E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 1 363 8.4E-120 T 28-03-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 ProSitePatterns PS00618 RecF protein signature 2. 314 332 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 ProSitePatterns PS00617 RecF protein signature 1. 117 137 - T 28-03-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 CNX65_RS00020 7909a994251d82df77cd9afcfe98b053 371 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 347 1.3E-17 T 28-03-2018 IPR003395 RecF/RecN/SMC, N-terminal CNX65_RS09655 d46ed4ebb4832142529b804d2f339b34 226 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 222 1.6E-29 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS09655 d46ed4ebb4832142529b804d2f339b34 226 Gene3D G3DSA:1.10.10.10 121 226 7.8E-34 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09655 d46ed4ebb4832142529b804d2f339b34 226 SMART SM00448 3 113 7.7E-40 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS09655 d46ed4ebb4832142529b804d2f339b34 226 SUPERFAMILY SSF52172 4 175 1.01E-40 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS09655 d46ed4ebb4832142529b804d2f339b34 226 SMART SM00862 146 222 2.6E-30 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS09655 d46ed4ebb4832142529b804d2f339b34 226 Gene3D G3DSA:3.40.50.2300 1 120 4.9E-38 T 28-03-2018 CNX65_RS09655 d46ed4ebb4832142529b804d2f339b34 226 Pfam PF00072 Response regulator receiver domain 5 113 1.3E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS16925 71ce7e9c0e74947ef91a4d1b1abe7217 422 SUPERFAMILY SSF52777 207 420 1.19E-25 T 28-03-2018 CNX65_RS16925 71ce7e9c0e74947ef91a4d1b1abe7217 422 Pfam PF00668 Condensation domain 33 416 1.4E-28 T 28-03-2018 IPR001242 Condensation domain CNX65_RS16925 71ce7e9c0e74947ef91a4d1b1abe7217 422 Gene3D G3DSA:3.30.559.10 6 176 9.5E-21 T 28-03-2018 CNX65_RS16925 71ce7e9c0e74947ef91a4d1b1abe7217 422 SUPERFAMILY SSF52777 27 169 8.23E-20 T 28-03-2018 CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 Gene3D G3DSA:3.40.50.980 94 275 1.6E-33 T 28-03-2018 CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 Pfam PF13193 AMP-binding enzyme C-terminal domain 540 613 2.8E-7 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 SUPERFAMILY SSF56801 46 625 3.92E-124 T 28-03-2018 CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 47 103 1.5E-12 T 28-03-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 Pfam PF00501 AMP-binding enzyme 110 525 1.5E-51 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 13 643 6.2E-243 T 28-03-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 Gene3D G3DSA:3.40.50.980 276 435 1.1E-29 T 28-03-2018 CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 ProSitePatterns PS00455 Putative AMP-binding domain signature. 269 280 - T 28-03-2018 IPR020845 AMP-binding, conserved site CNX65_RS00765 ad8558f0756aa8c3709abc2dcc0372bd 652 Gene3D G3DSA:3.30.300.30 520 629 3.3E-13 T 28-03-2018 CNX65_RS12610 9e80f690152503ea7f3d06e81ab7738e 512 Gene3D G3DSA:1.20.1250.20 39 234 4.6E-30 T 28-03-2018 CNX65_RS12610 9e80f690152503ea7f3d06e81ab7738e 512 Gene3D G3DSA:1.20.1250.20 285 499 4.9E-23 T 28-03-2018 CNX65_RS12610 9e80f690152503ea7f3d06e81ab7738e 512 Pfam PF07690 Major Facilitator Superfamily 52 443 2.2E-44 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS12610 9e80f690152503ea7f3d06e81ab7738e 512 SUPERFAMILY SSF103473 281 493 5.62E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12610 9e80f690152503ea7f3d06e81ab7738e 512 SUPERFAMILY SSF103473 38 231 5.62E-62 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12610 9e80f690152503ea7f3d06e81ab7738e 512 ProSitePatterns PS00216 Sugar transport proteins signature 1. 101 117 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS19245 df487d8a4e4828b2302e7688586c2793 57 Pfam PF01744 GLTT repeat (6 copies) 18 40 2.1E-6 T 28-03-2018 IPR008164 Repeat of unknown function XGLTT CNX65_RS33850 ac8783dbd466cc4f1eb544efeb17957c 314 TIGRFAM TIGR04382 myo_inos_iolC_N: 5-dehydro-2-deoxygluconokinase 1 304 7.5E-108 T 28-03-2018 IPR030830 5-Dehydro-2-deoxygluconokinase KEGG: 00562+2.7.1.92 CNX65_RS33850 ac8783dbd466cc4f1eb544efeb17957c 314 Gene3D G3DSA:3.40.1190.20 1 309 9.5E-77 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS33850 ac8783dbd466cc4f1eb544efeb17957c 314 Pfam PF00294 pfkB family carbohydrate kinase 2 297 9.6E-52 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS33850 ac8783dbd466cc4f1eb544efeb17957c 314 PRINTS PR00990 Ribokinase signature 181 196 6.1E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS33850 ac8783dbd466cc4f1eb544efeb17957c 314 PRINTS PR00990 Ribokinase signature 26 45 6.1E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS33850 ac8783dbd466cc4f1eb544efeb17957c 314 PRINTS PR00990 Ribokinase signature 220 231 6.1E-7 T 28-03-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 CNX65_RS33850 ac8783dbd466cc4f1eb544efeb17957c 314 SUPERFAMILY SSF53613 1 304 1.71E-72 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 ProSitePatterns PS00211 ABC transporters family signature. 469 483 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 Gene3D G3DSA:1.10.3720.10 17 282 3.3E-35 T 28-03-2018 CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 293 3.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 SUPERFAMILY SSF52540 305 574 1.85E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 SMART SM00382 345 546 1.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 SUPERFAMILY SSF161098 83 264 6.41E-19 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 Pfam PF00005 ABC transporter 337 496 4.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS30455 acac2f55674d8573ca569756dceb39e2 590 Gene3D G3DSA:3.40.50.300 314 582 8.0E-67 T 28-03-2018 CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 PRINTS PR01576 Peptide deformylase signature 87 98 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 PRINTS PR01576 Peptide deformylase signature 33 62 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 PRINTS PR01576 Peptide deformylase signature 99 117 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 PRINTS PR01576 Peptide deformylase signature 118 147 1.6E-29 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 Pfam PF01327 Polypeptide deformylase 4 150 6.8E-42 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 SUPERFAMILY SSF56420 3 170 3.53E-53 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 PIRSF PIRSF004749 1 167 2.0E-41 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 9 156 4.9E-36 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 Gene3D G3DSA:3.90.45.10 1 162 2.4E-55 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS26000 9c121103b4cfad73835806926ab4bde2 181 Hamap MF_00163 Peptide deformylase [def]. 2 160 27.123 T 28-03-2018 IPR023635 Peptide deformylase CNX65_RS32920 f6f6453c6a9cd879e884ef504559c33b 252 Hamap MF_01357 NAD(P)H-quinone oxidoreductase subunit J, chloroplastic [ndhJ]. 80 240 29.417 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32920 f6f6453c6a9cd879e884ef504559c33b 252 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 112 232 4.5E-44 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32920 f6f6453c6a9cd879e884ef504559c33b 252 SUPERFAMILY SSF143243 95 248 3.4E-49 T 28-03-2018 CNX65_RS32920 f6f6453c6a9cd879e884ef504559c33b 252 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 160 221 2.0E-20 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32920 f6f6453c6a9cd879e884ef504559c33b 252 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 110 231 5.5E-43 T 28-03-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS11035 6c7d9bcf8fe4bd9f2b8cae2efea7a29b 347 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 8 291 3.7E-54 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11035 6c7d9bcf8fe4bd9f2b8cae2efea7a29b 347 Pfam PF02470 MlaD protein 34 109 3.9E-13 T 28-03-2018 IPR003399 Mce/MlaD CNX65_RS32005 3684cc0cc6f67186c2ceff050e079e70 313 SUPERFAMILY SSF103481 40 142 6.67E-11 T 28-03-2018 CNX65_RS32005 3684cc0cc6f67186c2ceff050e079e70 313 Pfam PF00892 EamA-like transporter family 150 285 1.9E-20 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS32005 3684cc0cc6f67186c2ceff050e079e70 313 Pfam PF00892 EamA-like transporter family 13 139 7.4E-16 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS32005 3684cc0cc6f67186c2ceff050e079e70 313 SUPERFAMILY SSF103481 195 288 4.58E-16 T 28-03-2018 CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 153 207 2.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 SUPERFAMILY SSF46894 146 213 1.36E-18 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 SMART SM00421 150 207 2.4E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 Gene3D G3DSA:1.10.10.10 97 213 1.9E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 1.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 1.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 1.6E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS26770 13f6c6b36ff27a7e903d42fd7dc04651 213 Gene3D G3DSA:3.40.50.720 14 96 0.0068 T 28-03-2018 CNX65_RS02745 3d467ee456c14cd6609227c834158828 251 Pfam PF08445 FR47-like protein 146 225 4.1E-11 T 28-03-2018 IPR013653 FR47-like GO:0016747 CNX65_RS02745 3d467ee456c14cd6609227c834158828 251 SUPERFAMILY SSF55729 115 226 1.42E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS02745 3d467ee456c14cd6609227c834158828 251 Gene3D G3DSA:3.40.630.30 9 232 4.1E-15 T 28-03-2018 CNX65_RS08820 ca06f705fbd5bfdf29c7155630d423cd 197 Pfam PF13699 Domain of unknown function (DUF4157) 80 151 2.6E-26 T 28-03-2018 IPR025295 Domain of unknown function DUF4157 CNX65_RS15275 da4fd2f1fb589469d0065ce2b3de50bb 229 Gene3D G3DSA:2.60.120.180 22 228 7.1E-51 T 28-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CNX65_RS15275 da4fd2f1fb589469d0065ce2b3de50bb 229 Pfam PF01670 Glycosyl hydrolase family 12 77 226 3.6E-20 T 28-03-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 CNX65_RS15275 da4fd2f1fb589469d0065ce2b3de50bb 229 SUPERFAMILY SSF49899 29 227 7.46E-45 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS26360 41c0aad88836d63e2da207bc1e98d495 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 57 4.0E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS26360 41c0aad88836d63e2da207bc1e98d495 189 Gene3D G3DSA:1.10.357.10 8 189 3.5E-17 T 28-03-2018 CNX65_RS26360 41c0aad88836d63e2da207bc1e98d495 189 SUPERFAMILY SSF46689 7 73 2.21E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 SUPERFAMILY SSF51971 4 211 1.0E-58 T 28-03-2018 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 SUPERFAMILY SSF51971 260 317 1.0E-58 T 28-03-2018 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 Gene3D G3DSA:3.50.50.60 97 317 2.7E-61 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 SUPERFAMILY SSF51971 307 442 2.12E-6 T 28-03-2018 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 178 7.3E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 Gene3D G3DSA:3.50.50.60 2 96 2.4E-13 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 PRINTS PR00419 Adrenodoxin reductase family signature 31 44 1.8E-21 T 28-03-2018 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 PRINTS PR00419 Adrenodoxin reductase family signature 74 84 1.8E-21 T 28-03-2018 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 PRINTS PR00419 Adrenodoxin reductase family signature 6 28 1.8E-21 T 28-03-2018 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 PRINTS PR00419 Adrenodoxin reductase family signature 145 159 1.8E-21 T 28-03-2018 CNX65_RS00100 755bfb5b9f741c62e0ed5ff6e44f1d7f 448 PIRSF PIRSF000362 1 448 9.4E-164 T 28-03-2018 IPR021163 Ferredoxin-NADP+ reductase, adrenodoxin-type GO:0016491|GO:0055114 Reactome: R-HSA-196108|Reactome: R-HSA-211976|Reactome: R-HSA-2395516|Reactome: R-HSA-5579026 CNX65_RS07185 20c2fea131ba731fff180229733712e6 215 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 30 211 3.0E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS07185 20c2fea131ba731fff180229733712e6 215 SUPERFAMILY SSF161098 9 197 2.22E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS07185 20c2fea131ba731fff180229733712e6 215 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 10 106 1.1E-20 T 28-03-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0005215|GO:0006810|GO:0016021 CNX65_RS07185 20c2fea131ba731fff180229733712e6 215 Gene3D G3DSA:1.10.3720.10 3 213 6.9E-35 T 28-03-2018 CNX65_RS12700 65727ed3262dce6de71757a5b547dc3b 246 Pfam PF00413 Matrixin 160 243 4.3E-6 T 28-03-2018 IPR001818 Peptidase M10, metallopeptidase GO:0004222|GO:0006508|GO:0008270|GO:0031012 CNX65_RS12700 65727ed3262dce6de71757a5b547dc3b 246 Gene3D G3DSA:3.40.390.10 58 243 4.7E-13 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CNX65_RS12700 65727ed3262dce6de71757a5b547dc3b 246 SUPERFAMILY SSF55486 144 244 4.81E-12 T 28-03-2018 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 Gene3D G3DSA:1.25.40.70 219 276 0.26 T 28-03-2018 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 Gene3D G3DSA:1.25.40.70 282 352 5.3E-6 T 28-03-2018 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 Gene3D G3DSA:1.25.10.10 2 216 1.5E-8 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 Pfam PF13646 HEAT repeats 161 232 1.6E-7 T 28-03-2018 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 SMART SM00567 E-Z type HEAT repeats 23 50 320.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 SMART SM00567 E-Z type HEAT repeats 96 125 740.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 SMART SM00567 E-Z type HEAT repeats 171 200 86.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 SMART SM00567 E-Z type HEAT repeats 202 231 0.19 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 SMART SM00567 E-Z type HEAT repeats 261 296 1000.0 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS28100 48dec3831245ef92ed979bb8d395a1a6 358 SUPERFAMILY SSF48371 112 351 1.11E-15 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS31380 91645c24eb0ce135a397fd66459d1464 543 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 109 123 3.3E-5 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CNX65_RS31380 91645c24eb0ce135a397fd66459d1464 543 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 143 161 3.3E-5 T 28-03-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388 CNX65_RS31380 91645c24eb0ce135a397fd66459d1464 543 SUPERFAMILY SSF52096 257 543 2.32E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS31380 91645c24eb0ce135a397fd66459d1464 543 SUPERFAMILY SSF52096 19 270 5.97E-78 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS31380 91645c24eb0ce135a397fd66459d1464 543 Pfam PF01039 Carboxyl transferase domain 42 541 4.5E-195 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CNX65_RS31380 91645c24eb0ce135a397fd66459d1464 543 Gene3D G3DSA:3.90.226.10 9 272 1.8E-81 T 28-03-2018 CNX65_RS31380 91645c24eb0ce135a397fd66459d1464 543 Gene3D G3DSA:3.90.226.10 282 533 7.4E-72 T 28-03-2018 CNX65_RS01100 cf83490fe8af403d4f630c713cc2ad94 319 Gene3D G3DSA:3.60.21.10 38 306 6.9E-18 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS01100 cf83490fe8af403d4f630c713cc2ad94 319 SUPERFAMILY SSF56300 43 296 5.35E-25 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS01100 cf83490fe8af403d4f630c713cc2ad94 319 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 48 231 5.5E-8 T 28-03-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 CNX65_RS28295 2535d055b79e037966f134717874ecee 143 Gene3D G3DSA:2.10.260.10 78 125 3.6E-5 T 28-03-2018 CNX65_RS28295 2535d055b79e037966f134717874ecee 143 SUPERFAMILY SSF89447 2 135 1.12E-46 T 28-03-2018 CNX65_RS28295 2535d055b79e037966f134717874ecee 143 TIGRFAM TIGR00242 TIGR00242: division/cell wall cluster transcriptional repressor MraZ 2 136 2.9E-38 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CNX65_RS28295 2535d055b79e037966f134717874ecee 143 Gene3D G3DSA:2.10.260.10 9 27 6.4E-5 T 28-03-2018 CNX65_RS28295 2535d055b79e037966f134717874ecee 143 Hamap MF_01008 Transcriptional regulator MraZ [mraZ]. 1 143 52.955 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CNX65_RS28295 2535d055b79e037966f134717874ecee 143 ProDom PD006745 MRAZ YABB DIVISION CELL 3D-STRUCTURE UNCHARACTERIZED BCR SIMILAR PROTEIN 1 128 2.0E-47 T 28-03-2018 IPR003444 Transcriptional regulator MraZ GO:0003700|GO:0006355 CNX65_RS28295 2535d055b79e037966f134717874ecee 143 Pfam PF02381 MraZ protein, putative antitoxin-like 72 135 1.7E-20 T 28-03-2018 IPR020603 MraZ domain CNX65_RS28295 2535d055b79e037966f134717874ecee 143 Pfam PF02381 MraZ protein, putative antitoxin-like 2 70 4.5E-20 T 28-03-2018 IPR020603 MraZ domain CNX65_RS18755 85b252590b66b39ca4db193df3d21f78 484 Gene3D G3DSA:3.50.50.60 1 156 3.8E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18755 85b252590b66b39ca4db193df3d21f78 484 Gene3D G3DSA:3.50.50.60 157 483 1.8E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18755 85b252590b66b39ca4db193df3d21f78 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 6.7E-8 T 28-03-2018 CNX65_RS18755 85b252590b66b39ca4db193df3d21f78 484 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 6.7E-8 T 28-03-2018 CNX65_RS18755 85b252590b66b39ca4db193df3d21f78 484 Pfam PF00743 Flavin-binding monooxygenase-like 7 206 2.2E-14 T 28-03-2018 IPR020946 Flavin monooxygenase-like GO:0004499|GO:0050660|GO:0050661|GO:0055114 CNX65_RS18755 85b252590b66b39ca4db193df3d21f78 484 SUPERFAMILY SSF51905 4 225 5.18E-54 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18755 85b252590b66b39ca4db193df3d21f78 484 SUPERFAMILY SSF51905 263 456 5.25E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS30500 6460ca64cc0fba2be0c37a500107c27b 140 Pfam PF03795 YCII-related domain 1 113 8.2E-23 T 28-03-2018 IPR005545 YCII-related CNX65_RS30500 6460ca64cc0fba2be0c37a500107c27b 140 Gene3D G3DSA:3.30.70.1060 1 118 1.4E-36 T 28-03-2018 CNX65_RS30500 6460ca64cc0fba2be0c37a500107c27b 140 SUPERFAMILY SSF54909 1 115 1.21E-33 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS19130 beb072dc407b09aa984c5a86903176e1 121 Gene3D G3DSA:3.30.429.10 2 118 2.3E-28 T 28-03-2018 CNX65_RS19130 beb072dc407b09aa984c5a86903176e1 121 Pfam PF02962 5-carboxymethyl-2-hydroxymuconate isomerase 3 110 5.7E-10 T 28-03-2018 IPR004220 5-carboxymethyl-2-hydroxymuconate isomerase GO:0008704|GO:0019439 KEGG: 00350+5.3.3.10 CNX65_RS19130 beb072dc407b09aa984c5a86903176e1 121 SUPERFAMILY SSF55331 2 117 1.9E-23 T 28-03-2018 IPR014347 Tautomerase/MIF superfamily CNX65_RS18300 af4c1b24e5611c2f3ec9eae92db0ad50 335 Pfam PF02153 Prephenate dehydrogenase 73 279 6.4E-18 T 28-03-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 CNX65_RS18300 af4c1b24e5611c2f3ec9eae92db0ad50 335 SUPERFAMILY SSF51735 44 203 2.11E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS18300 af4c1b24e5611c2f3ec9eae92db0ad50 335 Gene3D G3DSA:3.40.50.720 29 213 1.1E-17 T 28-03-2018 CNX65_RS18300 af4c1b24e5611c2f3ec9eae92db0ad50 335 SUPERFAMILY SSF48179 207 329 1.31E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS18300 af4c1b24e5611c2f3ec9eae92db0ad50 335 Gene3D G3DSA:1.10.3660.10 215 335 3.5E-18 T 28-03-2018 CNX65_RS18240 e9784eace8615ba35fb68b4e4a431219 117 Pfam PF17195 Protein of unknown function (DUF5132) 22 68 8.1E-23 T 28-03-2018 IPR033456 Protein of unknown function DUF5132 CNX65_RS11545 7e9ffeba0e028d3219c10677447437f7 291 SUPERFAMILY SSF103481 190 283 7.06E-11 T 28-03-2018 CNX65_RS11545 7e9ffeba0e028d3219c10677447437f7 291 Pfam PF00892 EamA-like transporter family 145 277 2.9E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS14325 268a87a463c6708687aa648fca0f9e0d 518 Gene3D G3DSA:3.40.50.1820 29 494 8.8E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14325 268a87a463c6708687aa648fca0f9e0d 518 Pfam PF08386 TAP-like protein 417 505 1.9E-16 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS14325 268a87a463c6708687aa648fca0f9e0d 518 Pfam PF00561 alpha/beta hydrolase fold 95 255 1.9E-14 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS14325 268a87a463c6708687aa648fca0f9e0d 518 SUPERFAMILY SSF53474 173 241 4.74E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14325 268a87a463c6708687aa648fca0f9e0d 518 SUPERFAMILY SSF53474 338 490 4.74E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14325 268a87a463c6708687aa648fca0f9e0d 518 SUPERFAMILY SSF53474 82 139 4.74E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS31810 cf5e0577dd2661c5bb03fadd818801d9 569 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 118 130 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS31810 cf5e0577dd2661c5bb03fadd818801d9 569 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 4 27 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS31810 cf5e0577dd2661c5bb03fadd818801d9 569 Gene3D G3DSA:1.10.510.10 82 286 1.9E-42 T 28-03-2018 CNX65_RS31810 cf5e0577dd2661c5bb03fadd818801d9 569 SMART SM00220 1 259 4.6E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS31810 cf5e0577dd2661c5bb03fadd818801d9 569 SUPERFAMILY SSF56112 3 321 5.71E-68 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS31810 cf5e0577dd2661c5bb03fadd818801d9 569 Gene3D G3DSA:3.30.200.20 1 81 4.3E-22 T 28-03-2018 CNX65_RS31810 cf5e0577dd2661c5bb03fadd818801d9 569 Pfam PF00069 Protein kinase domain 3 199 1.7E-41 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS18540 48f5db151e918903ea4e9c6abfc87cb9 135 SUPERFAMILY SSF54427 4 129 4.11E-25 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS18540 48f5db151e918903ea4e9c6abfc87cb9 135 Gene3D G3DSA:3.10.450.50 1 130 1.6E-23 T 28-03-2018 CNX65_RS18540 48f5db151e918903ea4e9c6abfc87cb9 135 Pfam PF13577 SnoaL-like domain 5 121 1.9E-16 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS13760 1afa3caf1c82a4fa773695e9c687998b 302 Gene3D G3DSA:1.10.510.10 56 264 4.4E-20 T 28-03-2018 CNX65_RS13760 1afa3caf1c82a4fa773695e9c687998b 302 SUPERFAMILY SSF56112 30 263 2.59E-36 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS13760 1afa3caf1c82a4fa773695e9c687998b 302 Pfam PF01636 Phosphotransferase enzyme family 30 250 3.4E-26 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS14245 2730ca8e1c604bfb307f579a483306bd 510 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 41 452 2.2E-21 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CNX65_RS14245 2730ca8e1c604bfb307f579a483306bd 510 Gene3D G3DSA:3.40.720.10 2 500 5.4E-22 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CNX65_RS14245 2730ca8e1c604bfb307f579a483306bd 510 SUPERFAMILY SSF53649 3 123 2.73E-35 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CNX65_RS14245 2730ca8e1c604bfb307f579a483306bd 510 SUPERFAMILY SSF53649 256 482 2.73E-35 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CNX65_RS14345 1a81873ffa2913d037290e52b03456d4 126 SUPERFAMILY SSF55298 12 125 1.57E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS14345 1a81873ffa2913d037290e52b03456d4 126 Pfam PF01042 Endoribonuclease L-PSP 12 125 2.1E-17 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CNX65_RS14345 1a81873ffa2913d037290e52b03456d4 126 Gene3D G3DSA:3.30.1330.40 7 126 3.9E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS05005 1f96516a997838ed457246b62bfa9635 171 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 75 167 1.7E-7 T 28-03-2018 IPR026392 Exosortase/Archaeosortase domain CNX65_RS22030 265bfbc5f46b428300cf6ca0557cc416 200 Pfam PF00440 Bacterial regulatory proteins, tetR family 19 62 2.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22030 265bfbc5f46b428300cf6ca0557cc416 200 Gene3D G3DSA:1.10.10.60 3 64 2.4E-16 T 28-03-2018 CNX65_RS22030 265bfbc5f46b428300cf6ca0557cc416 200 SUPERFAMILY SSF46689 5 81 4.98E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22030 265bfbc5f46b428300cf6ca0557cc416 200 ProSitePatterns PS01081 TetR-type HTH domain signature. 30 60 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS22030 265bfbc5f46b428300cf6ca0557cc416 200 SUPERFAMILY SSF48498 87 198 6.02E-26 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS22030 265bfbc5f46b428300cf6ca0557cc416 200 Gene3D G3DSA:1.10.357.10 65 196 1.6E-22 T 28-03-2018 CNX65_RS23925 b8a29cb91bc3a0674e07755d89916f02 221 Pfam PF11512 Agrobacterium tumefaciens protein Atu4866 149 221 1.2E-32 T 28-03-2018 IPR020955 Uncharacterised protein family Atu4866 CNX65_RS23925 b8a29cb91bc3a0674e07755d89916f02 221 SUPERFAMILY SSF51338 17 70 1.43E-6 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS23925 b8a29cb91bc3a0674e07755d89916f02 221 Gene3D G3DSA:2.30.40.10 17 194 1.0E-9 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS08160 1e6fdd07bd3ea2c9479b42c9820bd659 391 Gene3D G3DSA:1.25.40.120 142 391 0.0022 T 28-03-2018 CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 SUPERFAMILY SSF75005 476 727 2.36E-32 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 78 235 7.4E-17 T 28-03-2018 CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 Gene3D G3DSA:2.115.10.20 417 495 9.7E-5 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 SUPERFAMILY SSF49899 29 238 2.43E-22 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 Gene3D G3DSA:2.115.10.20 496 727 4.3E-33 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 Gene3D G3DSA:2.60.120.200 27 238 2.9E-28 T 28-03-2018 CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 Pfam PF04616 Glycosyl hydrolases family 43 479 685 4.5E-12 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 Gene3D G3DSA:2.60.40.1080 336 416 0.0042 T 28-03-2018 CNX65_RS09270 5c2a1759a3ffbd49b1a2a26075687e98 739 Gene3D G3DSA:2.60.40.1080 239 331 0.03 T 28-03-2018 CNX65_RS17995 7a9d1886ead13bd2bb596f2df1d37d45 309 SUPERFAMILY SSF53474 23 276 8.11E-33 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17995 7a9d1886ead13bd2bb596f2df1d37d45 309 Pfam PF12697 Alpha/beta hydrolase family 29 272 9.1E-18 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS17995 7a9d1886ead13bd2bb596f2df1d37d45 309 Gene3D G3DSA:3.40.50.1820 9 282 2.1E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14765 c6ed6df6db9dba95bf581cbf21212a61 445 Gene3D G3DSA:2.60.40.10 4 110 2.2E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS14765 c6ed6df6db9dba95bf581cbf21212a61 445 Gene3D G3DSA:2.60.40.10 111 201 4.7E-7 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 Gene3D G3DSA:3.90.180.10 142 292 2.0E-13 T 28-03-2018 CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 93 3.9E-10 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 SUPERFAMILY SSF51735 107 226 2.89E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 Gene3D G3DSA:3.90.180.10 1 141 6.0E-42 T 28-03-2018 CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 SUPERFAMILY SSF50129 1 139 5.17E-30 T 28-03-2018 IPR011032 GroES-like CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 ProSitePatterns PS01162 Quinone oxidoreductase / zeta-crystallin signature. 134 155 - T 28-03-2018 IPR002364 Quinone oxidoreductase/zeta-crystallin, conserved site GO:0008270|GO:0016491 CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 SMART SM00829 10 291 8.8E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS16105 82fe1b8107f89df32587a911ce516cf4 293 Pfam PF13602 Zinc-binding dehydrogenase 195 291 7.6E-12 T 28-03-2018 CNX65_RS31050 ec5fab190f98f1f3e7b541c6bf669f00 130 Pfam PF00702 haloacid dehalogenase-like hydrolase 23 104 5.3E-9 T 28-03-2018 CNX65_RS31050 ec5fab190f98f1f3e7b541c6bf669f00 130 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 34 109 7.8E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS31050 ec5fab190f98f1f3e7b541c6bf669f00 130 Gene3D G3DSA:3.40.50.1000 1 124 8.7E-19 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS31050 ec5fab190f98f1f3e7b541c6bf669f00 130 SUPERFAMILY SSF56784 4 120 1.21E-23 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 Gene3D G3DSA:2.40.30.10 161 257 7.8E-18 T 28-03-2018 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 Gene3D G3DSA:3.40.50.80 258 387 7.3E-20 T 28-03-2018 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 SUPERFAMILY SSF63380 157 260 1.27E-18 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 PRINTS PR00409 Phthalate dioxygenase reductase family signature 355 363 5.9E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 PRINTS PR00409 Phthalate dioxygenase reductase family signature 247 261 5.9E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 PRINTS PR00409 Phthalate dioxygenase reductase family signature 269 288 5.9E-7 T 28-03-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 Pfam PF00042 Globin 7 104 9.3E-9 T 28-03-2018 IPR000971 Globin GO:0020037 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 SUPERFAMILY SSF46458 1 132 2.99E-34 T 28-03-2018 IPR009050 Globin-like CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 Gene3D G3DSA:1.10.490.10 1 160 7.6E-34 T 28-03-2018 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 Pfam PF00175 Oxidoreductase NAD-binding domain 272 369 2.0E-9 T 28-03-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 CNX65_RS19030 925e890a942cdf9f979ad4dd1d94dd8d 407 SUPERFAMILY SSF52343 263 388 2.36E-29 T 28-03-2018 CNX65_RS09070 548548c478f9af23dd9ed0273493da09 287 Gene3D G3DSA:1.10.1660.10 5 169 3.6E-19 T 28-03-2018 CNX65_RS09070 548548c478f9af23dd9ed0273493da09 287 SUPERFAMILY SSF46955 8 73 1.1E-12 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS09070 548548c478f9af23dd9ed0273493da09 287 Gene3D G3DSA:3.40.50.280 170 281 7.8E-17 T 28-03-2018 CNX65_RS09070 548548c478f9af23dd9ed0273493da09 287 SMART SM00422 7 76 9.2E-9 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS09070 548548c478f9af23dd9ed0273493da09 287 Pfam PF02310 B12 binding domain 177 266 2.1E-7 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS09070 548548c478f9af23dd9ed0273493da09 287 SUPERFAMILY SSF52242 172 267 3.45E-6 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS09070 548548c478f9af23dd9ed0273493da09 287 Pfam PF13411 MerR HTH family regulatory protein 10 69 5.1E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS00475 838cb85f938b85298e420e0c866e759b 374 Pfam PF13676 TIR domain 56 153 2.9E-12 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS00475 838cb85f938b85298e420e0c866e759b 374 SUPERFAMILY SSF52200 53 158 5.23E-13 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS00475 838cb85f938b85298e420e0c866e759b 374 SMART SM00255 53 207 0.002 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS00475 838cb85f938b85298e420e0c866e759b 374 Gene3D G3DSA:3.40.50.10140 47 208 1.1E-17 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS10845 8f4fd365bd0706c4d2c20ea2369c8d46 288 Gene3D G3DSA:1.10.260.40 1 90 3.1E-10 T 28-03-2018 CNX65_RS10845 8f4fd365bd0706c4d2c20ea2369c8d46 288 SUPERFAMILY SSF47413 9 64 2.45E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS10845 8f4fd365bd0706c4d2c20ea2369c8d46 288 Pfam PF13560 Helix-turn-helix domain 10 72 6.6E-16 T 28-03-2018 CNX65_RS10845 8f4fd365bd0706c4d2c20ea2369c8d46 288 SMART SM00530 14 69 3.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS24770 9a83cc91346009f78d6ee6e6381da46b 112 Pfam PF05331 Protein of unknown function (DUF742) 4 111 4.3E-32 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 Gene3D G3DSA:2.40.180.10 1 363 1.9E-160 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 Pfam PF06628 Catalase-related immune-responsive 423 483 3.3E-16 T 28-03-2018 IPR010582 Catalase immune-responsive domain KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 PRINTS PR00067 Catalase signature 129 147 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 PRINTS PR00067 Catalase signature 294 321 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 PRINTS PR00067 Catalase signature 326 352 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 PRINTS PR00067 Catalase signature 26 49 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 PRINTS PR00067 Catalase signature 89 107 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 PRINTS PR00067 Catalase signature 110 127 1.1E-71 T 28-03-2018 IPR018028 Catalase, mono-functional, haem-containing GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 PIRSF PIRSF038928 3 489 3.8E-216 T 28-03-2018 IPR024711 Catalase, mono-functional, haem-containing, clades 1 and 3 GO:0004096|GO:0006979|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 SUPERFAMILY SSF56634 6 485 8.51E-204 T 28-03-2018 IPR020835 Catalase-like domain GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 ProSitePatterns PS00438 Catalase proximal active site signature. 49 65 - T 28-03-2018 IPR024708 Catalase active site GO:0004096 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 SMART SM01060 13 399 1.3E-281 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS22115 9cf0d10f5cb56aa7f4a97b864e9fafd2 490 Pfam PF00199 Catalase 13 395 5.4E-184 T 28-03-2018 IPR011614 Catalase core domain GO:0004096|GO:0020037|GO:0055114 KEGG: 00380+1.11.1.6|KEGG: 00630+1.11.1.6|Reactome: R-HSA-3299685|Reactome: R-HSA-6798695 CNX65_RS33480 56fc8d25b8968e0a97f66a1c9916eea1 70 Gene3D G3DSA:1.10.10.10 21 67 1.0E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33480 56fc8d25b8968e0a97f66a1c9916eea1 70 Pfam PF08279 HTH domain 37 64 2.0E-4 T 28-03-2018 IPR013196 Helix-turn-helix, type 11 CNX65_RS19405 46ecbbc36ebf8c035c128051103fc1ed 221 Pfam PF14016 Protein of unknown function (DUF4232) 80 212 4.1E-30 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CNX65_RS28845 f7332a8438f7d46f167e22a703932c10 452 Gene3D G3DSA:1.20.1250.20 254 449 5.9E-18 T 28-03-2018 CNX65_RS28845 f7332a8438f7d46f167e22a703932c10 452 Pfam PF07690 Major Facilitator Superfamily 64 412 4.2E-16 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS28845 f7332a8438f7d46f167e22a703932c10 452 SUPERFAMILY SSF103473 40 448 7.06E-39 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS28845 f7332a8438f7d46f167e22a703932c10 452 Gene3D G3DSA:1.20.1250.20 50 237 8.4E-14 T 28-03-2018 CNX65_RS27525 161d048f99a9c018f58afb7003fe8736 203 SUPERFAMILY SSF46689 12 90 4.39E-20 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS27525 161d048f99a9c018f58afb7003fe8736 203 Pfam PF00440 Bacterial regulatory proteins, tetR family 26 71 7.3E-17 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS27525 161d048f99a9c018f58afb7003fe8736 203 Gene3D G3DSA:1.10.10.60 8 73 4.5E-23 T 28-03-2018 CNX65_RS27525 161d048f99a9c018f58afb7003fe8736 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 1.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS27525 161d048f99a9c018f58afb7003fe8736 203 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 1.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS27525 161d048f99a9c018f58afb7003fe8736 203 Gene3D G3DSA:1.10.357.10 74 200 9.3E-19 T 28-03-2018 CNX65_RS27525 161d048f99a9c018f58afb7003fe8736 203 SUPERFAMILY SSF48498 92 199 5.4E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 Gene3D G3DSA:3.40.50.1000 28 191 4.4E-20 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 176 1.4E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 93 106 1.0E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 141 161 1.0E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 123 139 1.0E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 1 7 1.0E-13 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 SUPERFAMILY SSF56784 2 181 2.03E-29 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34080 3f435b1ad8549af131162b8bc6abc8ea 195 Pfam PF13419 Haloacid dehalogenase-like hydrolase 79 175 8.7E-10 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 52 128 1.0E-19 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 Pfam PF14200 Ricin-type beta-trefoil lectin domain-like 134 193 5.9E-14 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 Gene3D G3DSA:2.80.10.50 152 193 2.6E-15 T 28-03-2018 CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 Gene3D G3DSA:2.80.10.50 43 110 2.7E-15 T 28-03-2018 CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 SUPERFAMILY SSF50370 48 188 6.29E-47 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 SUPERFAMILY SSF75005 227 496 1.62E-27 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 Gene3D G3DSA:2.115.10.20 194 506 1.0E-56 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 Pfam PF03664 Glycosyl hydrolase family 62 208 478 7.3E-153 T 28-03-2018 IPR005193 Glycoside hydrolase, family 62, arabinosidase GO:0046373|GO:0046556 KEGG: 00520+3.2.1.55 CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 SMART SM00458 52 188 3.1E-12 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS24490 129e595a5c37f264e88bc9f320f28e24 508 Gene3D G3DSA:4.10.1090.10 111 151 1.1E-16 T 28-03-2018 CNX65_RS07495 77b2a73dfbe2f6235c14e30d5594d291 99 Pfam PF13834 Domain of unknown function (DUF4193) 1 99 3.0E-44 T 28-03-2018 IPR025242 Protein of unknown function DUF4193 CNX65_RS22060 e733c052ada46359acdd3d9297de10fa 1033 Gene3D G3DSA:3.30.1490.130 713 740 0.2 T 28-03-2018 CNX65_RS22060 e733c052ada46359acdd3d9297de10fa 1033 Pfam PF13569 Domain of unknown function (DUF4132) 773 944 1.9E-48 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS22060 e733c052ada46359acdd3d9297de10fa 1033 Gene3D G3DSA:1.25.10.10 74 712 0.012 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS10510 c17070f87e8362bd2e24d2c8d20524e5 252 SUPERFAMILY SSF161098 2 247 6.21E-33 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS10510 c17070f87e8362bd2e24d2c8d20524e5 252 Gene3D G3DSA:1.10.3720.10 1 250 2.0E-30 T 28-03-2018 CNX65_RS10510 c17070f87e8362bd2e24d2c8d20524e5 252 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 236 1.4E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS27820 49da77eacaef03c380b6d7fa93c144f4 282 Pfam PF13560 Helix-turn-helix domain 14 75 3.9E-19 T 28-03-2018 CNX65_RS27820 49da77eacaef03c380b6d7fa93c144f4 282 Gene3D G3DSA:1.10.260.40 1 86 1.5E-15 T 28-03-2018 CNX65_RS27820 49da77eacaef03c380b6d7fa93c144f4 282 SUPERFAMILY SSF47413 10 74 9.57E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS27820 49da77eacaef03c380b6d7fa93c144f4 282 SMART SM00530 17 72 2.8E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS24120 3ebd4aeb005bb846cbdda55f74e4f4c5 253 Gene3D G3DSA:1.10.10.10 1 73 2.2E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24120 3ebd4aeb005bb846cbdda55f74e4f4c5 253 Pfam PF09339 IclR helix-turn-helix domain 4 53 1.3E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS24120 3ebd4aeb005bb846cbdda55f74e4f4c5 253 SUPERFAMILY SSF46785 1 73 7.21E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24120 3ebd4aeb005bb846cbdda55f74e4f4c5 253 SMART SM00346 1 91 3.4E-8 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS24120 3ebd4aeb005bb846cbdda55f74e4f4c5 253 Pfam PF01614 Bacterial transcriptional regulator 121 244 2.0E-20 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS24120 3ebd4aeb005bb846cbdda55f74e4f4c5 253 SUPERFAMILY SSF55781 86 248 3.99E-35 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS24120 3ebd4aeb005bb846cbdda55f74e4f4c5 253 Gene3D G3DSA:3.30.450.40 74 252 3.8E-35 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS20035 2a70db6d8a33c3004728799689bf38d8 250 SUPERFAMILY SSF53474 10 246 1.29E-54 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20035 2a70db6d8a33c3004728799689bf38d8 250 SMART SM00824 Thioesterase 25 242 1.2E-5 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CNX65_RS20035 2a70db6d8a33c3004728799689bf38d8 250 Gene3D G3DSA:3.40.50.1820 2 249 3.3E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20035 2a70db6d8a33c3004728799689bf38d8 250 Pfam PF00975 Thioesterase domain 23 244 5.9E-60 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS25800 9507ba527b0204cdc25c3f294fa6a1ba 370 PIRSF PIRSF036915 1 370 1.7E-165 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CNX65_RS25800 9507ba527b0204cdc25c3f294fa6a1ba 370 Gene3D G3DSA:3.20.20.70 2 362 4.2E-128 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS25800 9507ba527b0204cdc25c3f294fa6a1ba 370 Hamap MF_00493 Transaldolase [tal]. 1 370 155.89 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CNX65_RS25800 9507ba527b0204cdc25c3f294fa6a1ba 370 TIGRFAM TIGR00876 tal_mycobact: transaldolase 12 359 2.7E-136 T 28-03-2018 IPR004732 Transaldolase type 2 GO:0004801|GO:0005737|GO:0006098 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 CNX65_RS25800 9507ba527b0204cdc25c3f294fa6a1ba 370 ProSitePatterns PS01054 Transaldolase signature 1. 42 50 - T 28-03-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CNX65_RS25800 9507ba527b0204cdc25c3f294fa6a1ba 370 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 16 360 9.0E-78 T 28-03-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-71336 CNX65_RS25800 9507ba527b0204cdc25c3f294fa6a1ba 370 SUPERFAMILY SSF51569 6 362 2.56E-75 T 28-03-2018 CNX65_RS11255 c25ceef0c5253177c82a33c75eab9fb8 298 Pfam PF09754 PAC2 family 27 245 1.0E-53 T 28-03-2018 IPR019151 Proteasome assembly chaperone 2 CNX65_RS11255 c25ceef0c5253177c82a33c75eab9fb8 298 PIRSF PIRSF028754 8 296 2.8E-112 T 28-03-2018 IPR008492 Protein of unknown function DUF774 CNX65_RS11255 c25ceef0c5253177c82a33c75eab9fb8 298 Gene3D G3DSA:1.10.287.100 226 266 6.6E-11 T 28-03-2018 CNX65_RS11255 c25ceef0c5253177c82a33c75eab9fb8 298 SUPERFAMILY SSF159659 12 266 4.05E-92 T 28-03-2018 CNX65_RS21635 56c51a305295f2cd591acefe0328688d 554 Gene3D G3DSA:3.90.76.10 68 172 6.3E-20 T 28-03-2018 CNX65_RS21635 56c51a305295f2cd591acefe0328688d 554 Gene3D G3DSA:3.40.190.10 173 316 7.4E-29 T 28-03-2018 CNX65_RS21635 56c51a305295f2cd591acefe0328688d 554 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 95 457 3.3E-69 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS21635 56c51a305295f2cd591acefe0328688d 554 Gene3D G3DSA:3.10.105.10 317 521 4.7E-42 T 28-03-2018 CNX65_RS21635 56c51a305295f2cd591acefe0328688d 554 SUPERFAMILY SSF53850 46 552 1.45E-98 T 28-03-2018 CNX65_RS21635 56c51a305295f2cd591acefe0328688d 554 PIRSF PIRSF002741 11 554 5.1E-73 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS23705 74b4b91778dc04cb0b44f4bb6a325084 338 Gene3D G3DSA:2.60.40.1710 48 163 4.0E-5 T 28-03-2018 CNX65_RS23705 74b4b91778dc04cb0b44f4bb6a325084 338 Pfam PF06030 Bacterial protein of unknown function (DUF916) 54 147 2.5E-6 T 28-03-2018 IPR010317 Protein of unknown function DUF916, cell surface putative CNX65_RS23705 74b4b91778dc04cb0b44f4bb6a325084 338 Gene3D G3DSA:2.60.40.10 188 285 0.0015 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS29075 89ab9b92e11c132d120ac6c114fc1b53 79 Pfam PF13083 KH domain 6 66 2.6E-19 T 28-03-2018 CNX65_RS29075 89ab9b92e11c132d120ac6c114fc1b53 79 Hamap MF_00088 UPF0109 protein . 4 75 21.383 T 28-03-2018 IPR020627 Uncharacterised protein family UPF0109 CNX65_RS29075 89ab9b92e11c132d120ac6c114fc1b53 79 Gene3D G3DSA:3.30.300.20 1 76 1.4E-12 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS29075 89ab9b92e11c132d120ac6c114fc1b53 79 SUPERFAMILY SSF54814 18 61 1.5E-7 T 28-03-2018 IPR009019 K homology domain, prokaryotic type GO:0003723 CNX65_RS24250 789894952b4ea5798b3d5aab41c2678a 366 Gene3D G3DSA:3.40.50.280 92 217 1.1E-24 T 28-03-2018 CNX65_RS24250 789894952b4ea5798b3d5aab41c2678a 366 SUPERFAMILY SSF52242 95 212 4.08E-21 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS24250 789894952b4ea5798b3d5aab41c2678a 366 Pfam PF02607 B12 binding domain 14 85 1.4E-11 T 28-03-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS24250 789894952b4ea5798b3d5aab41c2678a 366 Pfam PF02310 B12 binding domain 97 206 1.9E-15 T 28-03-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 CNX65_RS24250 789894952b4ea5798b3d5aab41c2678a 366 Gene3D G3DSA:1.10.490.20 218 356 3.3E-21 T 28-03-2018 CNX65_RS11980 29751849351f5bad473d3a6fff38112d 430 Gene3D G3DSA:1.20.120.330 251 430 0.15 T 28-03-2018 CNX65_RS11980 29751849351f5bad473d3a6fff38112d 430 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 9 105 1.7E-18 T 28-03-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 CNX65_RS11980 29751849351f5bad473d3a6fff38112d 430 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 196 416 5.3E-27 T 28-03-2018 IPR010809 Flagellar hook-associated 2, C-terminal GO:0007155|GO:0009288 CNX65_RS25540 3e3996e4ec1bb0995deff1d8385856c4 190 Gene3D G3DSA:3.40.50.150 10 180 1.5E-10 T 28-03-2018 CNX65_RS25540 3e3996e4ec1bb0995deff1d8385856c4 190 SUPERFAMILY SSF53335 19 119 3.81E-9 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS25540 3e3996e4ec1bb0995deff1d8385856c4 190 SUPERFAMILY SSF53335 150 174 3.81E-9 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS18135 2a78b31e2ea3eb9893c0793f2b98e9db 83 SMART SM00823 Phosphopantetheine attachment site 11 80 2.5E-11 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS18135 2a78b31e2ea3eb9893c0793f2b98e9db 83 Pfam PF00550 Phosphopantetheine attachment site 19 74 9.8E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS18135 2a78b31e2ea3eb9893c0793f2b98e9db 83 Gene3D G3DSA:1.10.1200.10 5 81 2.5E-20 T 28-03-2018 CNX65_RS18135 2a78b31e2ea3eb9893c0793f2b98e9db 83 SUPERFAMILY SSF47336 6 80 5.5E-17 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS17270 aba88511af8b7a72e332462cb8d15748 192 SMART SM00530 12 67 2.5E-17 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS17270 aba88511af8b7a72e332462cb8d15748 192 Pfam PF07883 Cupin domain 106 173 4.2E-11 T 28-03-2018 IPR013096 Cupin 2, conserved barrel CNX65_RS17270 aba88511af8b7a72e332462cb8d15748 192 SUPERFAMILY SSF47413 8 72 5.07E-19 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS17270 aba88511af8b7a72e332462cb8d15748 192 SUPERFAMILY SSF51182 64 173 1.85E-19 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS17270 aba88511af8b7a72e332462cb8d15748 192 Gene3D G3DSA:1.10.260.40 1 64 2.0E-20 T 28-03-2018 CNX65_RS17270 aba88511af8b7a72e332462cb8d15748 192 Pfam PF13560 Helix-turn-helix domain 9 67 1.2E-15 T 28-03-2018 CNX65_RS17270 aba88511af8b7a72e332462cb8d15748 192 Gene3D G3DSA:2.60.120.10 65 187 3.7E-19 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS07960 39c22e3aaa2dd599492c47b058ef5e16 124 Gene3D G3DSA:1.10.287.1060 2 123 1.2E-4 T 28-03-2018 CNX65_RS23295 acd355fda8e414e51a6bfe56122e05ba 331 SUPERFAMILY SSF52266 144 328 5.92E-23 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS23295 acd355fda8e414e51a6bfe56122e05ba 331 Gene3D G3DSA:3.40.50.1110 143 331 2.4E-22 T 28-03-2018 CNX65_RS23295 acd355fda8e414e51a6bfe56122e05ba 331 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 150 317 1.5E-20 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS23295 acd355fda8e414e51a6bfe56122e05ba 331 Gene3D G3DSA:2.60.120.260 13 128 1.2E-12 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS33895 f6c767902406d2b050511e5ef5acf1ab 274 Gene3D G3DSA:1.10.260.40 5 84 2.4E-6 T 28-03-2018 CNX65_RS33895 f6c767902406d2b050511e5ef5acf1ab 274 SMART SM00530 18 72 0.0016 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS33895 f6c767902406d2b050511e5ef5acf1ab 274 Pfam PF13560 Helix-turn-helix domain 18 67 1.5E-6 T 28-03-2018 CNX65_RS13385 ce04bd82e122abef58b8c2d389232375 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 4.3E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13385 ce04bd82e122abef58b8c2d389232375 196 Gene3D G3DSA:1.10.357.10 12 196 1.5E-26 T 28-03-2018 CNX65_RS13385 ce04bd82e122abef58b8c2d389232375 196 SUPERFAMILY SSF46689 7 85 2.6E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 162 177 6.3E-14 T 28-03-2018 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 297 312 6.3E-14 T 28-03-2018 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 312 328 6.3E-14 T 28-03-2018 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 14 36 6.3E-14 T 28-03-2018 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 15 332 2.2E-74 T 28-03-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 Gene3D G3DSA:3.30.9.10 169 338 1.1E-42 T 28-03-2018 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 Gene3D G3DSA:3.50.50.60 3 168 6.4E-19 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 Pfam PF01494 FAD binding domain 13 183 1.3E-16 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 SUPERFAMILY SSF51905 10 193 6.13E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32935 ca9ff0cd7f703ba5c3d88500d53df11a 426 SUPERFAMILY SSF51905 287 385 6.13E-48 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS32270 b4618cb85fb0b51ef521f41cf03da3bd 540 TIGRFAM TIGR03919 T7SS_EccB: type VII secretion protein EccB 136 510 7.7E-66 T 28-03-2018 IPR007795 Type VII secretion system EccB CNX65_RS32270 b4618cb85fb0b51ef521f41cf03da3bd 540 Pfam PF05108 Type VII secretion system ESX-1, transport TM domain B 4 523 3.0E-119 T 28-03-2018 IPR007795 Type VII secretion system EccB CNX65_RS16025 b1c4061fd8664168e50176924b4ca879 381 Pfam PF02040 Arsenical pump membrane protein 41 371 8.3E-18 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CNX65_RS16025 b1c4061fd8664168e50176924b4ca879 381 PRINTS PR00758 Arsenical pump membrane protein signature 84 108 1.2E-5 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CNX65_RS16025 b1c4061fd8664168e50176924b4ca879 381 PRINTS PR00758 Arsenical pump membrane protein signature 248 272 1.2E-5 T 28-03-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 Pfam PF02222 ATP-grasp domain 115 283 8.0E-53 T 28-03-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 Gene3D G3DSA:3.30.470.20 187 382 1.1E-44 T 28-03-2018 CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 SUPERFAMILY SSF51246 310 388 2.43E-17 T 28-03-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 9 366 40.104 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 Gene3D G3DSA:3.40.50.20 7 88 1.8E-22 T 28-03-2018 CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 SUPERFAMILY SSF52440 8 102 2.45E-23 T 28-03-2018 IPR016185 Pre-ATP-grasp domain CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 10 371 1.7E-122 T 28-03-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 SUPERFAMILY SSF56059 106 304 4.6E-59 T 28-03-2018 CNX65_RS31270 1aac0293a12cf188baec6aa579602f07 396 Gene3D G3DSA:3.30.1490.20 89 186 4.7E-19 T 28-03-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0003824|GO:0005524 CNX65_RS24650 8a998e44c29fa93f6664efe64ab29969 728 Gene3D G3DSA:2.60.120.200 59 265 1.1E-17 T 28-03-2018 CNX65_RS24650 8a998e44c29fa93f6664efe64ab29969 728 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 68 214 8.1E-7 T 28-03-2018 CNX65_RS24650 8a998e44c29fa93f6664efe64ab29969 728 SUPERFAMILY SSF52317 450 572 6.41E-7 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS24650 8a998e44c29fa93f6664efe64ab29969 728 Gene3D G3DSA:3.40.50.880 339 712 2.3E-23 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS24650 8a998e44c29fa93f6664efe64ab29969 728 SUPERFAMILY SSF49899 61 247 1.23E-8 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 SUPERFAMILY SSF51905 6 305 9.97E-31 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 Gene3D G3DSA:3.50.50.60 129 231 2.4E-17 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 129 141 8.1E-16 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 107 115 8.1E-16 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 144 168 8.1E-16 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 270 288 8.1E-16 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 11 33 8.1E-16 T 28-03-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 Gene3D G3DSA:3.50.50.60 232 335 0.016 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 260 282 2.4E-11 T 28-03-2018 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 2.4E-11 T 28-03-2018 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 2.4E-11 T 28-03-2018 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 148 166 2.4E-11 T 28-03-2018 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 10 231 1.2E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09465 1372fb7645d028d31a2598fe9a1c360e 342 Gene3D G3DSA:3.50.50.60 4 128 1.3E-15 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28880 99c0ec7e0a744b38c252ffb64bef5868 599 Gene3D G3DSA:3.90.1310.10 233 306 4.9E-4 T 28-03-2018 CNX65_RS28880 99c0ec7e0a744b38c252ffb64bef5868 599 Gene3D G3DSA:3.40.710.10 307 597 1.0E-56 T 28-03-2018 CNX65_RS28880 99c0ec7e0a744b38c252ffb64bef5868 599 SUPERFAMILY SSF56601 260 584 3.32E-57 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS28880 99c0ec7e0a744b38c252ffb64bef5868 599 Pfam PF00905 Penicillin binding protein transpeptidase domain 324 580 6.4E-41 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CNX65_RS28880 99c0ec7e0a744b38c252ffb64bef5868 599 SUPERFAMILY SSF56519 149 303 1.24E-8 T 28-03-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 CNX65_RS28880 99c0ec7e0a744b38c252ffb64bef5868 599 Gene3D G3DSA:3.10.450.100 27 132 2.2E-8 T 28-03-2018 CNX65_RS28880 99c0ec7e0a744b38c252ffb64bef5868 599 Pfam PF05223 NTF2-like N-terminal transpeptidase domain 29 137 5.1E-14 T 28-03-2018 IPR007887 NTF2-like N-terminal transpeptidase GO:0046677 CNX65_RS00980 f64e8e724f2d6af5db1b71a9ecb3ca5d 331 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 234 299 1.2E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS00980 f64e8e724f2d6af5db1b71a9ecb3ca5d 331 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 232 318 1.7E-21 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS00980 f64e8e724f2d6af5db1b71a9ecb3ca5d 331 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS00980 f64e8e724f2d6af5db1b71a9ecb3ca5d 331 Pfam PF00005 ABC transporter 25 182 4.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS00980 f64e8e724f2d6af5db1b71a9ecb3ca5d 331 Gene3D G3DSA:3.40.50.300 1 329 2.8E-73 T 28-03-2018 CNX65_RS00980 f64e8e724f2d6af5db1b71a9ecb3ca5d 331 SMART SM00382 33 231 5.1E-16 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS00980 f64e8e724f2d6af5db1b71a9ecb3ca5d 331 SUPERFAMILY SSF52540 3 253 9.35E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29970 e4a4f60cad7166dab258180990029316 253 SMART SM00382 30 225 2.5E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS29970 e4a4f60cad7166dab258180990029316 253 Pfam PF00005 ABC transporter 22 177 1.5E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS29970 e4a4f60cad7166dab258180990029316 253 Gene3D G3DSA:3.40.50.300 3 249 8.1E-53 T 28-03-2018 CNX65_RS29970 e4a4f60cad7166dab258180990029316 253 SUPERFAMILY SSF52540 4 234 8.81E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02040 8738a1bcec3993fc28aaf7a4742e260b 274 SUPERFAMILY SSF51556 2 274 9.36E-62 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS02040 8738a1bcec3993fc28aaf7a4742e260b 274 Pfam PF04909 Amidohydrolase 3 274 3.5E-38 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS02040 8738a1bcec3993fc28aaf7a4742e260b 274 Gene3D G3DSA:3.20.20.140 1 274 3.1E-34 T 28-03-2018 CNX65_RS22200 3f460db058bdafd0ff06e40d99412666 271 Pfam PF13560 Helix-turn-helix domain 5 84 4.2E-18 T 28-03-2018 CNX65_RS22200 3f460db058bdafd0ff06e40d99412666 271 SMART SM00530 9 81 4.8E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS22200 3f460db058bdafd0ff06e40d99412666 271 SUPERFAMILY SSF47413 29 80 1.76E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS22200 3f460db058bdafd0ff06e40d99412666 271 Gene3D G3DSA:1.10.260.40 1 81 7.7E-17 T 28-03-2018 CNX65_RS31005 5d06738141d7472318cac6682ff8440e 204 SUPERFAMILY SSF53474 5 200 2.13E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS31005 5d06738141d7472318cac6682ff8440e 204 Gene3D G3DSA:3.40.50.1820 6 203 8.1E-12 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 SUPERFAMILY SSF52016 423 612 5.49E-59 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 4 611 45.301 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 SUPERFAMILY SSF143975 4 422 1.83E-136 T 28-03-2018 CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 122 132 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 Pfam PF00920 Dehydratase family 34 608 9.5E-216 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 18 611 1.2E-239 T 28-03-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 Gene3D G3DSA:3.40.50.2300 53 172 1.1E-5 T 28-03-2018 CNX65_RS29630 62046444cac1ea6f057e4d155b654257 614 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 511 522 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS06220 5ccabf2ed6f54bc1b5a3a665867b59ac 263 Pfam PF13673 Acetyltransferase (GNAT) domain 41 120 7.8E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS06220 5ccabf2ed6f54bc1b5a3a665867b59ac 263 Gene3D G3DSA:3.40.630.30 1 125 2.4E-21 T 28-03-2018 CNX65_RS06220 5ccabf2ed6f54bc1b5a3a665867b59ac 263 SUPERFAMILY SSF55729 4 211 4.08E-27 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS07050 225a3d6b412524139c174f00b9518074 620 Pfam PF00920 Dehydratase family 66 599 1.7E-161 T 28-03-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS07050 225a3d6b412524139c174f00b9518074 620 SUPERFAMILY SSF52016 419 601 3.37E-57 T 28-03-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel CNX65_RS07050 225a3d6b412524139c174f00b9518074 620 SUPERFAMILY SSF143975 1 418 1.83E-141 T 28-03-2018 CNX65_RS07050 225a3d6b412524139c174f00b9518074 620 TIGRFAM TIGR01196 edd: phosphogluconate dehydratase 2 602 2.2E-295 T 28-03-2018 IPR004786 6-phosphogluconate dehydratase GO:0004456|GO:0009255 KEGG: 00030+4.2.1.12 CNX65_RS07050 225a3d6b412524139c174f00b9518074 620 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 155 165 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS07050 225a3d6b412524139c174f00b9518074 620 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 505 516 - T 28-03-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824|GO:0008152 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 36 95 3.7E-18 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 Gene3D G3DSA:3.40.190.10 217 297 5.0E-21 T 28-03-2018 CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 SUPERFAMILY SSF46785 35 119 1.69E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 Gene3D G3DSA:3.40.190.10 121 216 4.8E-21 T 28-03-2018 CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 Pfam PF03466 LysR substrate binding domain 139 324 5.3E-37 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 51 62 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 72 83 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 62 72 4.8E-6 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 Gene3D G3DSA:1.10.10.10 30 116 1.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02000 381a2eab160526251e3d50291e3ec33e 326 SUPERFAMILY SSF53850 123 324 6.3E-36 T 28-03-2018 CNX65_RS00350 eea28709a552b3273ebc9892d84841a8 275 SMART SM00448 5 131 4.4E-13 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS00350 eea28709a552b3273ebc9892d84841a8 275 Gene3D G3DSA:3.40.50.2300 1 158 1.1E-22 T 28-03-2018 CNX65_RS00350 eea28709a552b3273ebc9892d84841a8 275 SMART SM00850 167 267 5.1E-30 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CNX65_RS00350 eea28709a552b3273ebc9892d84841a8 275 SUPERFAMILY SSF52172 4 143 1.99E-23 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS00350 eea28709a552b3273ebc9892d84841a8 275 Pfam PF04397 LytTr DNA-binding domain 169 266 8.0E-22 T 28-03-2018 IPR007492 LytTR DNA-binding domain GO:0003677 CNX65_RS00350 eea28709a552b3273ebc9892d84841a8 275 Pfam PF00072 Response regulator receiver domain 7 131 1.1E-14 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS00350 eea28709a552b3273ebc9892d84841a8 275 Gene3D G3DSA:2.40.50.40 159 227 4.1E-15 T 28-03-2018 CNX65_RS29995 9bb4586530a4a765e5a06662e1077a40 538 Pfam PF08386 TAP-like protein 412 512 3.1E-24 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS29995 9bb4586530a4a765e5a06662e1077a40 538 Gene3D G3DSA:3.40.50.1820 66 501 3.0E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29995 9bb4586530a4a765e5a06662e1077a40 538 Pfam PF00561 alpha/beta hydrolase fold 98 258 3.8E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS29995 9bb4586530a4a765e5a06662e1077a40 538 SUPERFAMILY SSF53474 397 500 8.53E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29995 9bb4586530a4a765e5a06662e1077a40 538 SUPERFAMILY SSF53474 83 146 8.53E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29995 9bb4586530a4a765e5a06662e1077a40 538 SUPERFAMILY SSF53474 188 242 8.53E-20 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS34380 68f05398185a0acd1e394e1ea9bb8835 386 Pfam PF17210 SdrD B-like domain 59 132 1.2E-12 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS34380 68f05398185a0acd1e394e1ea9bb8835 386 SUPERFAMILY SSF117074 48 130 4.97E-13 T 28-03-2018 CNX65_RS34380 68f05398185a0acd1e394e1ea9bb8835 386 Gene3D G3DSA:2.60.40.10 51 304 1.3E-14 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS34380 68f05398185a0acd1e394e1ea9bb8835 386 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 350 383 5.1E-4 T 28-03-2018 CNX65_RS28415 0273a6a4049ae0c7edb100cbf81eb18a 203 Gene3D G3DSA:3.90.950.20 33 200 8.2E-53 T 28-03-2018 CNX65_RS28415 0273a6a4049ae0c7edb100cbf81eb18a 203 Pfam PF02464 Competence-damaged protein 42 197 1.1E-44 T 28-03-2018 IPR008136 CinA, C-terminal CNX65_RS28415 0273a6a4049ae0c7edb100cbf81eb18a 203 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 50 198 2.7E-29 T 28-03-2018 IPR008136 CinA, C-terminal CNX65_RS28415 0273a6a4049ae0c7edb100cbf81eb18a 203 SUPERFAMILY SSF142433 42 198 1.44E-43 T 28-03-2018 IPR008136 CinA, C-terminal CNX65_RS11280 82b48d50f9965af7e09081c45214ffb9 413 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 13 344 7.4E-43 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CNX65_RS11280 82b48d50f9965af7e09081c45214ffb9 413 SUPERFAMILY SSF51395 10 349 1.83E-89 T 28-03-2018 CNX65_RS11280 82b48d50f9965af7e09081c45214ffb9 413 Gene3D G3DSA:3.20.20.70 4 362 1.7E-98 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS06120 59e9c90915c8ff99ba94192deac5a415 146 Pfam PF00545 ribonuclease 61 140 9.8E-29 T 28-03-2018 IPR000026 Guanine-specific ribonuclease N1/T1/U2 GO:0003723|GO:0004521 CNX65_RS06120 59e9c90915c8ff99ba94192deac5a415 146 Gene3D G3DSA:3.10.450.30 53 146 1.7E-32 T 28-03-2018 CNX65_RS06120 59e9c90915c8ff99ba94192deac5a415 146 SUPERFAMILY SSF53933 53 143 9.92E-33 T 28-03-2018 IPR016191 Ribonuclease/ribotoxin GO:0003723|GO:0004540 CNX65_RS22050 41faf93f5d442ac5c7455d9a68b82046 101 SUPERFAMILY SSF52540 4 99 7.37E-29 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22050 41faf93f5d442ac5c7455d9a68b82046 101 Gene3D G3DSA:3.40.50.300 2 99 3.6E-28 T 28-03-2018 CNX65_RS22050 41faf93f5d442ac5c7455d9a68b82046 101 Pfam PF00005 ABC transporter 4 31 1.4E-8 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS09760 467836cea25fdc38be5b5fab4526fbb5 556 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 523 555 0.0033 T 28-03-2018 CNX65_RS09760 467836cea25fdc38be5b5fab4526fbb5 556 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 66 341 4.6E-59 T 28-03-2018 IPR026588 Choice-of-anchor A domain CNX65_RS16400 03e8dc0e4807f2ef5ec4b8dc3147c6fa 129 Gene3D G3DSA:3.10.450.50 2 120 1.2E-20 T 28-03-2018 CNX65_RS16400 03e8dc0e4807f2ef5ec4b8dc3147c6fa 129 SUPERFAMILY SSF54427 5 125 1.12E-19 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS16400 03e8dc0e4807f2ef5ec4b8dc3147c6fa 129 Pfam PF12680 SnoaL-like domain 12 112 2.4E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 Gene3D G3DSA:3.40.50.2300 78 190 3.4E-26 T 28-03-2018 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 Gene3D G3DSA:1.10.10.10 1 64 1.3E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 Pfam PF13377 Periplasmic binding protein-like domain 192 355 4.0E-38 T 28-03-2018 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 28-03-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 SUPERFAMILY SSF53822 80 358 1.36E-39 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 Pfam PF08220 DeoR-like helix-turn-helix domain 6 58 6.3E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 3.7E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 3.7E-8 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 SMART SM00420 6 58 5.1E-13 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 Gene3D G3DSA:3.40.50.2300 191 358 1.9E-35 T 28-03-2018 CNX65_RS14735 1e0587d25b22dc3ac687f12607849486 361 SUPERFAMILY SSF46785 5 58 1.61E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 160 179 7.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 88 99 7.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 88 99 1.8E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 160 179 1.8E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 19 36 1.8E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 134 150 1.8E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 18 189 5.3E-5 T 28-03-2018 CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 SUPERFAMILY SSF51735 15 267 1.78E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 Gene3D G3DSA:3.40.50.720 9 279 9.7E-53 T 28-03-2018 CNX65_RS34190 576e90ae79d63092c9c43cd20bc155ea 297 Pfam PF00106 short chain dehydrogenase 18 202 1.7E-46 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24260 c71c1d27b1f78f7ea82ec1ab6aefdced 131 Gene3D G3DSA:3.30.160.100 1 106 4.2E-12 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS24260 c71c1d27b1f78f7ea82ec1ab6aefdced 131 SUPERFAMILY SSF69754 9 92 2.35E-5 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS06055 1bd2247711a9cbed3042f967be530684 280 Gene3D G3DSA:3.90.260.10 153 238 1.9E-8 T 28-03-2018 IPR002931 Transglutaminase-like CNX65_RS06055 1bd2247711a9cbed3042f967be530684 280 SMART SM00460 168 235 2.2E-21 T 28-03-2018 IPR002931 Transglutaminase-like CNX65_RS06055 1bd2247711a9cbed3042f967be530684 280 Pfam PF08379 Bacterial transglutaminase-like N-terminal region 6 83 4.9E-19 T 28-03-2018 IPR013589 Bacterial transglutaminase-like, N-terminal CNX65_RS06055 1bd2247711a9cbed3042f967be530684 280 SUPERFAMILY SSF54001 9 261 1.23E-39 T 28-03-2018 CNX65_RS06055 1bd2247711a9cbed3042f967be530684 280 Pfam PF01841 Transglutaminase-like superfamily 126 233 6.3E-25 T 28-03-2018 IPR002931 Transglutaminase-like CNX65_RS06810 8b57787b6375554fa2523e961f67a9dc 557 SUPERFAMILY SSF81342 23 302 7.06E-62 T 28-03-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 CNX65_RS06810 8b57787b6375554fa2523e961f67a9dc 557 Gene3D G3DSA:1.20.810.10 25 445 5.9E-100 T 28-03-2018 IPR027387 Cytochrome b/b6-like domain Reactome: R-HSA-611105 CNX65_RS06810 8b57787b6375554fa2523e961f67a9dc 557 Pfam PF13631 Cytochrome b(N-terminal)/b6/petB 124 297 8.0E-61 T 28-03-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 CNX65_RS11155 e08112f32f56a57c9d1202fdd0df2c55 204 Pfam PF12079 Protein of unknown function (DUF3558) 16 200 5.0E-22 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS12665 8d2532f41f6c71507108431643b7ca77 244 Pfam PF09509 Protein of unknown function (Hypoth_ymh) 114 237 7.1E-27 T 28-03-2018 IPR012654 Conserved hypothetical protein CHP02391 CNX65_RS33310 fa38cae3bc8a70e501fa91109c0b173c 381 Gene3D G3DSA:2.40.440.10 227 354 9.5E-27 T 28-03-2018 CNX65_RS33310 fa38cae3bc8a70e501fa91109c0b173c 381 SUPERFAMILY SSF141523 230 352 2.49E-26 T 28-03-2018 CNX65_RS33310 fa38cae3bc8a70e501fa91109c0b173c 381 Pfam PF03734 L,D-transpeptidase catalytic domain 232 352 1.4E-18 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 SMART SM00065 30 180 2.2E-10 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 SUPERFAMILY SSF55781 34 181 1.86E-20 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 PIRSF PIRSF036625 1 244 2.7E-50 T 28-03-2018 IPR012074 GAF-ANTAR transcription anti-termination regulator, putative CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 Pfam PF03861 ANTAR domain 185 237 1.2E-19 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 Gene3D G3DSA:1.10.10.10 195 239 2.4E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 Pfam PF13185 GAF domain 30 170 1.7E-14 T 28-03-2018 IPR003018 GAF domain GO:0005515 CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 SMART SM01012 182 237 2.3E-22 T 28-03-2018 IPR005561 ANTAR domain GO:0003723 CNX65_RS10980 3f8d34230dc79895c3c42d7195428171 244 Gene3D G3DSA:3.30.450.40 5 194 8.6E-30 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS30685 5d2b03eae5ee33a8c597c10297634d19 234 Gene3D G3DSA:3.40.50.1820 30 231 1.0E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30685 5d2b03eae5ee33a8c597c10297634d19 234 SUPERFAMILY SSF53474 82 184 1.37E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS30685 5d2b03eae5ee33a8c597c10297634d19 234 Pfam PF06259 Alpha/beta hydrolase 22 181 3.2E-36 T 28-03-2018 IPR010427 Protein of unknown function DUF1023 CNX65_RS17550 75e1a844081fff3911c1f32fa7df8b56 293 Pfam PF13560 Helix-turn-helix domain 21 89 2.5E-11 T 28-03-2018 CNX65_RS17550 75e1a844081fff3911c1f32fa7df8b56 293 Gene3D G3DSA:1.10.260.40 3 100 8.2E-11 T 28-03-2018 CNX65_RS17550 75e1a844081fff3911c1f32fa7df8b56 293 SMART SM00530 9 86 2.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS17550 75e1a844081fff3911c1f32fa7df8b56 293 SUPERFAMILY SSF47413 35 83 6.33E-6 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS12820 3004bb94d308fb7c89523d5a78fb479e 464 SUPERFAMILY SSF53300 42 215 2.38E-24 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS12820 3004bb94d308fb7c89523d5a78fb479e 464 Gene3D G3DSA:3.40.50.410 40 219 5.0E-25 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS12820 3004bb94d308fb7c89523d5a78fb479e 464 Pfam PF13768 von Willebrand factor type A domain 42 196 3.8E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS12820 3004bb94d308fb7c89523d5a78fb479e 464 SMART SM00327 38 212 5.6E-12 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS19555 d565b7cafde6149e3aa4ae093792dfa4 313 Pfam PF00781 Diacylglycerol kinase catalytic domain 7 120 6.8E-16 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CNX65_RS19555 d565b7cafde6149e3aa4ae093792dfa4 313 Gene3D G3DSA:3.40.50.10330 1 138 1.1E-20 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CNX65_RS19555 d565b7cafde6149e3aa4ae093792dfa4 313 SUPERFAMILY SSF111331 4 304 8.5E-44 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CNX65_RS12475 2acc4efa275321324ae5f2f697b5b8ea 121 Pfam PF01638 HxlR-like helix-turn-helix 28 116 6.1E-25 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS12475 2acc4efa275321324ae5f2f697b5b8ea 121 SUPERFAMILY SSF46785 14 119 6.52E-32 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12475 2acc4efa275321324ae5f2f697b5b8ea 121 Gene3D G3DSA:1.10.10.10 10 120 3.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01765 8626abdec7a186382914f49d0c58d12e 163 SUPERFAMILY SSF53056 24 161 6.8E-33 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS01765 8626abdec7a186382914f49d0c58d12e 163 Pfam PF00484 Carbonic anhydrase 32 94 3.6E-12 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS01765 8626abdec7a186382914f49d0c58d12e 163 SMART SM00947 24 163 3.0E-26 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS01765 8626abdec7a186382914f49d0c58d12e 163 Gene3D G3DSA:3.40.1050.10 1 163 3.2E-30 T 28-03-2018 IPR001765 Carbonic anhydrase GO:0004089|GO:0008270 KEGG: 00910+4.2.1.1|MetaCyc: PWY-241|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6142|MetaCyc: PWY-7115|MetaCyc: PWY-7117 CNX65_RS18365 78809b0e62454b560e79365f8c94ac33 336 Gene3D G3DSA:3.40.47.10 163 336 4.5E-22 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS18365 78809b0e62454b560e79365f8c94ac33 336 Gene3D G3DSA:3.40.47.10 4 162 1.6E-13 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS18365 78809b0e62454b560e79365f8c94ac33 336 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 246 335 3.4E-14 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS18365 78809b0e62454b560e79365f8c94ac33 336 SUPERFAMILY SSF53901 7 335 5.76E-28 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS18365 78809b0e62454b560e79365f8c94ac33 336 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 108 184 8.7E-7 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS04995 c82eb5df911624892bc680f81829bd31 191 Pfam PF02632 BioY family 48 185 2.5E-34 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CNX65_RS04995 c82eb5df911624892bc680f81829bd31 191 PIRSF PIRSF016661 12 191 1.9E-35 T 28-03-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 CNX65_RS01285 486d0586fb308649cbe630286fdca404 460 Pfam PF07075 Protein of unknown function (DUF1343) 100 459 2.1E-118 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CNX65_RS01285 486d0586fb308649cbe630286fdca404 460 PIRSF PIRSF016719 72 460 1.8E-123 T 28-03-2018 IPR008302 Uncharacterised conserved protein UCP016719 CNX65_RS18880 82971972a63c012eeb6bfa2a5b6f58c5 459 SUPERFAMILY SSF53383 5 376 3.2E-86 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS18880 82971972a63c012eeb6bfa2a5b6f58c5 459 Gene3D G3DSA:3.40.640.10 33 268 4.8E-43 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS18880 82971972a63c012eeb6bfa2a5b6f58c5 459 Gene3D G3DSA:3.90.1150.10 269 387 1.2E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS18880 82971972a63c012eeb6bfa2a5b6f58c5 459 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 34 303 7.1E-22 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CNX65_RS07610 3e9084fc06ebee4d13655c1ca261e95c 118 Gene3D G3DSA:1.10.287.1060 20 113 3.4E-4 T 28-03-2018 CNX65_RS16075 848142aa4e55cfeff8fc3871464a3106 114 Gene3D G3DSA:3.30.750.24 3 114 5.1E-20 T 28-03-2018 IPR002645 STAS domain CNX65_RS16075 848142aa4e55cfeff8fc3871464a3106 114 SUPERFAMILY SSF52091 10 110 7.26E-19 T 28-03-2018 IPR002645 STAS domain CNX65_RS16075 848142aa4e55cfeff8fc3871464a3106 114 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 9 108 4.5E-16 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS16075 848142aa4e55cfeff8fc3871464a3106 114 Pfam PF01740 STAS domain 12 109 2.5E-12 T 28-03-2018 IPR002645 STAS domain CNX65_RS15450 c65099cb53df07a054a82572d613cf05 358 TIGRFAM TIGR02637 RhaS: rhamnose ABC transporter, rhamnose-binding protein 59 358 1.1E-112 T 28-03-2018 IPR013459 Rhamnose ABC transporter, substrate-binding protein RhaS GO:0015762 CNX65_RS15450 c65099cb53df07a054a82572d613cf05 358 SUPERFAMILY SSF53822 57 358 1.63E-59 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS15450 c65099cb53df07a054a82572d613cf05 358 Gene3D G3DSA:3.40.50.2300 168 357 2.0E-19 T 28-03-2018 CNX65_RS15450 c65099cb53df07a054a82572d613cf05 358 Gene3D G3DSA:3.40.50.2300 56 167 8.0E-15 T 28-03-2018 CNX65_RS15450 c65099cb53df07a054a82572d613cf05 358 Pfam PF13407 Periplasmic binding protein domain 59 315 2.6E-51 T 28-03-2018 IPR025997 Periplasmic binding protein CNX65_RS17275 16eb9668275509e8f8594a69b5a961b4 242 Gene3D G3DSA:3.40.50.300 32 171 4.0E-35 T 28-03-2018 CNX65_RS17275 16eb9668275509e8f8594a69b5a961b4 242 Pfam PF00265 Thymidine kinase 33 224 7.4E-23 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CNX65_RS17275 16eb9668275509e8f8594a69b5a961b4 242 Gene3D G3DSA:3.30.60.20 175 238 6.1E-14 T 28-03-2018 CNX65_RS17275 16eb9668275509e8f8594a69b5a961b4 242 SUPERFAMILY SSF52540 32 171 4.89E-27 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17275 16eb9668275509e8f8594a69b5a961b4 242 PIRSF PIRSF035805 30 234 7.8E-36 T 28-03-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 CNX65_RS06370 2ae63c70a313180e39b051a0d3c48f03 83 Gene3D G3DSA:1.10.10.10 4 77 1.8E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06370 2ae63c70a313180e39b051a0d3c48f03 83 Pfam PF12728 Helix-turn-helix domain 3 46 9.9E-8 T 28-03-2018 CNX65_RS25005 0d63e781698e905f48a9770783497c8e 246 SMART SM00530 35 90 1.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS25005 0d63e781698e905f48a9770783497c8e 246 Gene3D G3DSA:1.10.260.40 25 101 5.9E-10 T 28-03-2018 CNX65_RS25005 0d63e781698e905f48a9770783497c8e 246 SUPERFAMILY SSF47413 28 89 1.66E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS25005 0d63e781698e905f48a9770783497c8e 246 Pfam PF13560 Helix-turn-helix domain 32 89 1.0E-11 T 28-03-2018 CNX65_RS00130 a3f2bf48dd92cbd7f87b124ab44b0352 474 Pfam PF13672 Protein phosphatase 2C 17 199 2.3E-12 T 28-03-2018 CNX65_RS00130 a3f2bf48dd92cbd7f87b124ab44b0352 474 SMART SM00332 2 233 3.3E-25 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS00130 a3f2bf48dd92cbd7f87b124ab44b0352 474 SMART SM00331 11 235 3.1E-38 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS00130 a3f2bf48dd92cbd7f87b124ab44b0352 474 SUPERFAMILY SSF81606 4 234 2.88E-63 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS00130 a3f2bf48dd92cbd7f87b124ab44b0352 474 Gene3D G3DSA:3.60.40.10 5 235 4.6E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 Pfam PF00082 Subtilase family 166 366 1.4E-21 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 SUPERFAMILY SSF54897 38 106 7.37E-9 T 28-03-2018 IPR009020 Protease propeptides/proteinase inhibitor I9 CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 Gene3D G3DSA:3.40.50.200 93 380 2.0E-66 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 143 154 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 Pfam PF05922 Peptidase inhibitor I9 74 106 2.0E-6 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 180 190 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 138 157 6.9E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 176 189 6.9E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 PRINTS PR00723 Subtilisin serine protease family (S8) signature 329 345 6.9E-13 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 Gene3D G3DSA:3.30.70.80 27 92 9.1E-13 T 28-03-2018 IPR010259 Peptidase S8 propeptide/proteinase inhibitor I9 Reactome: R-HSA-381426|Reactome: R-HSA-8866427|Reactome: R-HSA-8957275|Reactome: R-HSA-8964038 CNX65_RS08565 bb45fa48690f365b00d6e918554c9859 381 SUPERFAMILY SSF52743 110 367 5.63E-62 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS31000 c8b5858a8df029990074ac354518e16d 160 SUPERFAMILY SSF55826 8 158 4.71E-44 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS31000 c8b5858a8df029990074ac354518e16d 160 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 8 159 3.3E-53 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CNX65_RS31000 c8b5858a8df029990074ac354518e16d 160 Pfam PF04073 Aminoacyl-tRNA editing domain 37 150 9.9E-27 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS31000 c8b5858a8df029990074ac354518e16d 160 Gene3D G3DSA:3.90.960.10 2 160 1.4E-44 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS31000 c8b5858a8df029990074ac354518e16d 160 PIRSF PIRSF006181 4 160 2.2E-51 T 28-03-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC CNX65_RS12970 008de210157e516d5ca08770783b6607 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12970 008de210157e516d5ca08770783b6607 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 28 45 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12970 008de210157e516d5ca08770783b6607 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 146 162 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12970 008de210157e516d5ca08770783b6607 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12970 008de210157e516d5ca08770783b6607 312 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 101 112 1.3E-16 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12970 008de210157e516d5ca08770783b6607 312 Gene3D G3DSA:3.40.50.720 12 311 6.7E-59 T 28-03-2018 CNX65_RS12970 008de210157e516d5ca08770783b6607 312 SUPERFAMILY SSF51735 24 276 5.63E-52 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12970 008de210157e516d5ca08770783b6607 312 Pfam PF00106 short chain dehydrogenase 27 226 2.4E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS03905 62dfb571405e93ee171ab81fdb3c5328 434 SUPERFAMILY SSF103473 3 382 2.62E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS03905 62dfb571405e93ee171ab81fdb3c5328 434 ProSitePatterns PS00216 Sugar transport proteins signature 1. 58 74 - T 28-03-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 CNX65_RS03905 62dfb571405e93ee171ab81fdb3c5328 434 Gene3D G3DSA:1.20.1250.20 194 393 5.1E-11 T 28-03-2018 CNX65_RS03905 62dfb571405e93ee171ab81fdb3c5328 434 Gene3D G3DSA:1.20.1250.20 2 193 2.8E-29 T 28-03-2018 CNX65_RS03905 62dfb571405e93ee171ab81fdb3c5328 434 Pfam PF07690 Major Facilitator Superfamily 11 342 7.2E-37 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS22120 efa4b9cff8c3e3650d254ca94106feda 224 Gene3D G3DSA:3.40.50.880 1 209 1.6E-40 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS22120 efa4b9cff8c3e3650d254ca94106feda 224 SUPERFAMILY SSF52317 2 216 1.67E-41 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS22120 efa4b9cff8c3e3650d254ca94106feda 224 Pfam PF00117 Glutamine amidotransferase class-I 21 178 1.2E-13 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS22510 be515e635b91bb46e747bd28c6360962 320 Gene3D G3DSA:1.20.120.450 40 201 5.1E-14 T 28-03-2018 CNX65_RS22510 be515e635b91bb46e747bd28c6360962 320 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 55 257 5.2E-14 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS22510 be515e635b91bb46e747bd28c6360962 320 SUPERFAMILY SSF109854 49 199 2.29E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS22510 be515e635b91bb46e747bd28c6360962 320 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 59 195 3.2E-11 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS34385 aea08cff299bff0b8deb91c224f378a2 193 Pfam PF00692 dUTPase 70 176 1.1E-10 T 28-03-2018 IPR029054 dUTPase-like CNX65_RS34385 aea08cff299bff0b8deb91c224f378a2 193 Gene3D G3DSA:2.70.40.10 1 159 5.0E-48 T 28-03-2018 CNX65_RS34385 aea08cff299bff0b8deb91c224f378a2 193 TIGRFAM TIGR02274 dCTP_deam: deoxycytidine triphosphate deaminase 3 181 2.8E-63 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CNX65_RS34385 aea08cff299bff0b8deb91c224f378a2 193 SUPERFAMILY SSF51283 2 183 7.07E-57 T 28-03-2018 IPR029054 dUTPase-like CNX65_RS34385 aea08cff299bff0b8deb91c224f378a2 193 Hamap MF_00146 dCTP deaminase [dcd]. 1 182 34.841 T 28-03-2018 IPR011962 dCTP deaminase GO:0006229|GO:0008829 KEGG: 00240+3.5.4.13|MetaCyc: PWY-7187 CNX65_RS32205 997c79ae5e73b048c5c2ca8410d60c2f 72 Gene3D G3DSA:1.10.287.1060 1 68 3.0E-5 T 28-03-2018 CNX65_RS13035 5a713ed15ad56388e7597cda172f0c2f 227 SUPERFAMILY SSF53448 5 203 1.48E-25 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS13035 5a713ed15ad56388e7597cda172f0c2f 227 Gene3D G3DSA:3.90.550.10 4 205 1.2E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS13035 5a713ed15ad56388e7597cda172f0c2f 227 Pfam PF00535 Glycosyl transferase family 2 7 143 1.1E-8 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS32910 6b9bb9ac62c1a2268a704dd1c9d1b68b 254 Gene3D G3DSA:3.40.30.10 90 190 1.3E-13 T 28-03-2018 CNX65_RS32910 6b9bb9ac62c1a2268a704dd1c9d1b68b 254 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 29 180 5.6E-43 T 28-03-2018 CNX65_RS32910 6b9bb9ac62c1a2268a704dd1c9d1b68b 254 SUPERFAMILY SSF52833 20 188 7.6E-43 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS32910 6b9bb9ac62c1a2268a704dd1c9d1b68b 254 PIRSF PIRSF000216 5 239 1.4E-57 T 28-03-2018 IPR002023 NADH-quinone oxidoreductase subunit E-like GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS06005 07296da685d9adbd2a219e40242979b2 421 TIGRFAM TIGR00260 thrC: threonine synthase 67 395 3.1E-79 T 28-03-2018 IPR004450 Threonine synthase-like CNX65_RS06005 07296da685d9adbd2a219e40242979b2 421 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 88 389 9.4E-67 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS06005 07296da685d9adbd2a219e40242979b2 421 Gene3D G3DSA:3.40.50.1100 98 206 1.0E-20 T 28-03-2018 CNX65_RS06005 07296da685d9adbd2a219e40242979b2 421 Gene3D G3DSA:3.40.50.1100 207 405 9.6E-41 T 28-03-2018 CNX65_RS06005 07296da685d9adbd2a219e40242979b2 421 SUPERFAMILY SSF53686 16 403 3.67E-83 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS08525 d87daddbe90d01ba16f33a4bc27235f4 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 66 2.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS08525 d87daddbe90d01ba16f33a4bc27235f4 195 SUPERFAMILY SSF46689 6 85 4.41E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS08525 d87daddbe90d01ba16f33a4bc27235f4 195 Gene3D G3DSA:1.10.10.60 1 64 5.3E-17 T 28-03-2018 CNX65_RS08525 d87daddbe90d01ba16f33a4bc27235f4 195 Gene3D G3DSA:1.10.357.10 65 195 2.9E-5 T 28-03-2018 CNX65_RS08525 d87daddbe90d01ba16f33a4bc27235f4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 41 64 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS08525 d87daddbe90d01ba16f33a4bc27235f4 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.1E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS22775 fa7f641cf3c7f709fcf44a0b866e87a1 315 SUPERFAMILY SSF52540 108 245 4.32E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22775 fa7f641cf3c7f709fcf44a0b866e87a1 315 Pfam PF02223 Thymidylate kinase 112 244 6.9E-16 T 28-03-2018 CNX65_RS22775 fa7f641cf3c7f709fcf44a0b866e87a1 315 Gene3D G3DSA:3.40.50.300 106 302 1.3E-24 T 28-03-2018 CNX65_RS06750 c4518684ba671fc698eb78061a804449 124 Pfam PF01521 Iron-sulphur cluster biosynthesis 20 121 1.2E-18 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CNX65_RS06750 c4518684ba671fc698eb78061a804449 124 SUPERFAMILY SSF89360 20 113 6.67E-27 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CNX65_RS06750 c4518684ba671fc698eb78061a804449 124 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 20 124 7.0E-35 T 28-03-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 CNX65_RS06750 c4518684ba671fc698eb78061a804449 124 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 106 123 - T 28-03-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 CNX65_RS06750 c4518684ba671fc698eb78061a804449 124 Gene3D G3DSA:2.60.300.12 20 124 1.2E-31 T 28-03-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 CNX65_RS15175 e9b1821d3c3dc5995e09a9fc995557fc 221 SUPERFAMILY SSF46689 7 90 2.22E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS15175 e9b1821d3c3dc5995e09a9fc995557fc 221 SUPERFAMILY SSF48498 85 186 2.06E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS15175 e9b1821d3c3dc5995e09a9fc995557fc 221 Gene3D G3DSA:1.10.357.10 1 192 1.0E-30 T 28-03-2018 CNX65_RS15175 e9b1821d3c3dc5995e09a9fc995557fc 221 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.6E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS15175 e9b1821d3c3dc5995e09a9fc995557fc 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 40 63 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS15175 e9b1821d3c3dc5995e09a9fc995557fc 221 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 20 33 1.6E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16365 676df2b221f78453659b61c75fdfe96e 364 Pfam PF06224 Winged helix DNA-binding domain 32 354 9.8E-47 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CNX65_RS01820 9aba7ee8dea1be982ebadc84fb7dfc8b 485 Pfam PF00990 Diguanylate cyclase, GGDEF domain 280 391 2.5E-28 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS01820 9aba7ee8dea1be982ebadc84fb7dfc8b 485 Gene3D G3DSA:3.30.70.270 273 466 4.5E-50 T 28-03-2018 CNX65_RS01820 9aba7ee8dea1be982ebadc84fb7dfc8b 485 SMART SM00267 269 461 1.4E-41 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS01820 9aba7ee8dea1be982ebadc84fb7dfc8b 485 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 278 399 5.2E-32 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS01820 9aba7ee8dea1be982ebadc84fb7dfc8b 485 SUPERFAMILY SSF55073 286 461 2.59E-37 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 SMART SM00421 1 58 2.6E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 SUPERFAMILY SSF46894 3 54 1.8E-16 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 4 18 1.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 34 46 1.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 18 34 1.5E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 Gene3D G3DSA:1.10.10.10 1 58 1.5E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 Pfam PF00196 Bacterial regulatory proteins, luxR family 4 54 5.4E-13 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS25470 6dc39b249c12958f3f65b45b542a6d1a 61 ProSitePatterns PS00622 LuxR-type HTH domain signature. 18 45 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 SUPERFAMILY SSF52540 2 227 9.76E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 SMART SM00382 309 494 7.0E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 SMART SM00382 28 219 4.4E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 Gene3D G3DSA:3.40.50.300 1 234 1.2E-58 T 28-03-2018 CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 Gene3D G3DSA:3.40.50.300 282 516 1.3E-46 T 28-03-2018 CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 SUPERFAMILY SSF52540 278 508 1.45E-46 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 Pfam PF00005 ABC transporter 19 170 3.4E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS11660 8bb82f61d12a3317d7222f068214d657 535 Pfam PF00005 ABC transporter 301 445 3.2E-17 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS14795 5bb7a6e59882e44162a8f61689103e63 146 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 6 145 4.9E-28 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 CNX65_RS14795 5bb7a6e59882e44162a8f61689103e63 146 Pfam PF06841 T4-like virus tail tube protein gp19 11 143 1.4E-25 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 CNX65_RS32805 c6a50809277f75016dce56d0e485726f 162 Pfam PF00037 4Fe-4S binding domain 62 82 4.4E-8 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS32805 c6a50809277f75016dce56d0e485726f 162 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 28-03-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site CNX65_RS32805 c6a50809277f75016dce56d0e485726f 162 SUPERFAMILY SSF54862 7 88 1.73E-15 T 28-03-2018 CNX65_RS32805 c6a50809277f75016dce56d0e485726f 162 Gene3D G3DSA:3.30.70.20 4 71 7.9E-13 T 28-03-2018 CNX65_RS32805 c6a50809277f75016dce56d0e485726f 162 Gene3D G3DSA:3.30.70.20 72 138 9.1E-7 T 28-03-2018 CNX65_RS03980 559d347ebaef58a3aba3a3167c9b1c9a 319 Gene3D G3DSA:3.20.20.60 1 253 4.8E-61 T 28-03-2018 CNX65_RS03980 559d347ebaef58a3aba3a3167c9b1c9a 319 PIRSF PIRSF015582 1 318 2.6E-87 T 28-03-2018 IPR011206 Citrate lyase beta subunit-like CNX65_RS03980 559d347ebaef58a3aba3a3167c9b1c9a 319 Pfam PF03328 HpcH/HpaI aldolase/citrate lyase family 10 241 3.5E-45 T 28-03-2018 IPR005000 HpcH/HpaI aldolase/citrate lyase domain GO:0003824 CNX65_RS03980 559d347ebaef58a3aba3a3167c9b1c9a 319 SUPERFAMILY SSF51621 6 252 1.18E-63 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS23350 ad4bad639d87598c513cd04d65e47d90 419 Pfam PF13796 Putative sensor 31 200 4.1E-15 T 28-03-2018 IPR025828 Putative sensor domain CNX65_RS23350 ad4bad639d87598c513cd04d65e47d90 419 SMART SM00387 329 419 0.0029 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS23350 ad4bad639d87598c513cd04d65e47d90 419 Pfam PF07730 Histidine kinase 229 295 5.9E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS23350 ad4bad639d87598c513cd04d65e47d90 419 Gene3D G3DSA:3.30.565.10 290 419 2.3E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS23350 ad4bad639d87598c513cd04d65e47d90 419 SUPERFAMILY SSF55874 334 416 1.04E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS01700 63ca346e9cb46224f6fb17887c47f756 334 SUPERFAMILY SSF81345 4 329 4.97E-83 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS01700 63ca346e9cb46224f6fb17887c47f756 334 Pfam PF01032 FecCD transport family 20 328 3.5E-94 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS01700 63ca346e9cb46224f6fb17887c47f756 334 Gene3D G3DSA:1.10.3470.10 4 333 2.5E-70 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS03305 6be60f6304954a6bee016eac25275610 313 SUPERFAMILY SSF109998 31 170 5.89E-7 T 28-03-2018 IPR027304 Trigger factor/SurA domain CNX65_RS03305 6be60f6304954a6bee016eac25275610 313 Gene3D G3DSA:1.10.4030.10 27 262 2.9E-4 T 28-03-2018 CNX65_RS05165 e3dce75393b2e2db87d09794018f659f 73 Pfam PF12277 Protein of unknown function (DUF3618) 2 47 7.5E-18 T 28-03-2018 IPR022062 Protein of unknown function DUF3618 CNX65_RS34855 d5ce96dc8ba3a8e1ad31e7918d33f404 399 SUPERFAMILY SSF55073 238 397 1.49E-39 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS34855 d5ce96dc8ba3a8e1ad31e7918d33f404 399 SMART SM00267 221 399 8.8E-44 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS34855 d5ce96dc8ba3a8e1ad31e7918d33f404 399 Gene3D G3DSA:3.30.70.270 226 399 2.8E-46 T 28-03-2018 CNX65_RS34855 d5ce96dc8ba3a8e1ad31e7918d33f404 399 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 230 398 3.5E-43 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS34855 d5ce96dc8ba3a8e1ad31e7918d33f404 399 Pfam PF00990 Diguanylate cyclase, GGDEF domain 232 394 6.0E-39 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS18180 2c9018660d2dcc1e471069f9a067dcb3 180 SUPERFAMILY SSF52540 4 179 1.1E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS18180 2c9018660d2dcc1e471069f9a067dcb3 180 Gene3D G3DSA:3.40.50.300 56 180 1.2E-6 T 28-03-2018 CNX65_RS18180 2c9018660d2dcc1e471069f9a067dcb3 180 Gene3D G3DSA:3.40.50.300 2 55 1.2E-6 T 28-03-2018 CNX65_RS07590 18cbdcb032713a20c130c8bcffeeb8e6 123 SUPERFAMILY SSF101386 14 118 1.83E-33 T 28-03-2018 CNX65_RS07590 18cbdcb032713a20c130c8bcffeeb8e6 123 PIRSF PIRSF029826 6 121 2.5E-39 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CNX65_RS07590 18cbdcb032713a20c130c8bcffeeb8e6 123 Pfam PF12643 MazG-like family 45 115 1.8E-8 T 28-03-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 CNX65_RS07590 18cbdcb032713a20c130c8bcffeeb8e6 123 Gene3D G3DSA:1.10.4010.10 6 117 4.1E-27 T 28-03-2018 CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 SUPERFAMILY SSF50998 100 368 2.62E-18 T 28-03-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 SMART SM00773 4 77 1.8E-18 T 28-03-2018 IPR008893 WGR domain CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 SUPERFAMILY SSF142921 6 72 1.23E-9 T 28-03-2018 IPR008893 WGR domain CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 Pfam PF05406 WGR domain 6 74 3.6E-17 T 28-03-2018 IPR008893 WGR domain CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 Gene3D G3DSA:2.130.10.10 82 251 4.5E-5 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 Pfam PF13360 PQQ-like domain 250 368 2.7E-8 T 28-03-2018 IPR002372 Pyrrolo-quinoline quinone repeat CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 Gene3D G3DSA:2.20.140.10 8 79 6.8E-14 T 28-03-2018 IPR008893 WGR domain CNX65_RS08135 be58db6168cbeff8600ef6351cb57cbf 477 Gene3D G3DSA:2.140.10.10 252 469 1.1E-16 T 28-03-2018 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 3.4E-14 T 28-03-2018 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 326 3.4E-14 T 28-03-2018 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 326 342 3.4E-14 T 28-03-2018 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 SUPERFAMILY SSF51905 298 390 3.02E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 SUPERFAMILY SSF51905 1 168 3.02E-38 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 Pfam PF01494 FAD binding domain 3 166 2.6E-6 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 Pfam PF01494 FAD binding domain 290 347 3.2E-9 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS17455 2579e9a41c1390d0da4b0a1bd371da99 408 Gene3D G3DSA:3.50.50.60 1 402 1.7E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 6 331 4.4E-83 T 28-03-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 Gene3D G3DSA:3.30.9.10 94 157 3.2E-6 T 28-03-2018 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 SUPERFAMILY SSF54373 198 291 1.14E-11 T 28-03-2018 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 Pfam PF01266 FAD dependent oxidoreductase 6 330 3.6E-44 T 28-03-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 Gene3D G3DSA:3.40.50.720 1 93 5.1E-10 T 28-03-2018 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 SUPERFAMILY SSF51905 293 332 5.96E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 SUPERFAMILY SSF51905 4 200 5.96E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS02095 13d2a7c686ea8ffe538c46fe02f9c806 335 Gene3D G3DSA:3.30.9.10 158 291 1.7E-20 T 28-03-2018 CNX65_RS17210 cafebc40ee7d4fdbc2ad2817e8f8fff4 133 SUPERFAMILY SSF54593 4 121 3.62E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS17210 cafebc40ee7d4fdbc2ad2817e8f8fff4 133 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 117 2.8E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS17210 cafebc40ee7d4fdbc2ad2817e8f8fff4 133 Gene3D G3DSA:3.10.180.10 2 130 5.5E-23 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS34530 aa47dcd6d7ed658c44305944f5859859 264 ProSitePatterns PS00211 ABC transporters family signature. 155 169 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS34530 aa47dcd6d7ed658c44305944f5859859 264 Gene3D G3DSA:3.40.50.300 17 264 2.8E-74 T 28-03-2018 CNX65_RS34530 aa47dcd6d7ed658c44305944f5859859 264 Pfam PF00005 ABC transporter 35 183 8.9E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS34530 aa47dcd6d7ed658c44305944f5859859 264 SMART SM00382 44 232 6.9E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS34530 aa47dcd6d7ed658c44305944f5859859 264 PIRSF PIRSF039085 16 259 1.4E-113 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CNX65_RS34530 aa47dcd6d7ed658c44305944f5859859 264 SUPERFAMILY SSF52540 20 253 1.02E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10585 c8ae80b9d4e47d0aefd96e3f66cf345e 194 Gene3D G3DSA:3.30.460.10 24 192 4.3E-50 T 28-03-2018 CNX65_RS10585 c8ae80b9d4e47d0aefd96e3f66cf345e 194 Pfam PF04229 GrpB protein 29 185 1.3E-48 T 28-03-2018 IPR007344 GrpB/Dephospho-CoA kinase CNX65_RS10585 c8ae80b9d4e47d0aefd96e3f66cf345e 194 SUPERFAMILY SSF81301 31 189 7.52E-44 T 28-03-2018 CNX65_RS18830 1856e9878dd9577ddcfe687e3d85112b 274 TIGRFAM TIGR00026 hi_GC_TIGR00026: deazaflavin-dependent oxidoreductase, nitroreductase family 25 135 1.4E-31 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CNX65_RS18830 1856e9878dd9577ddcfe687e3d85112b 274 Gene3D G3DSA:1.20.120.520 141 274 3.2E-24 T 28-03-2018 CNX65_RS18830 1856e9878dd9577ddcfe687e3d85112b 274 Gene3D G3DSA:2.30.110.10 1 138 1.2E-43 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS18830 1856e9878dd9577ddcfe687e3d85112b 274 SUPERFAMILY SSF50475 26 130 5.23E-8 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS18830 1856e9878dd9577ddcfe687e3d85112b 274 Pfam PF04075 F420H(2)-dependent quinone reductase 14 136 1.0E-36 T 28-03-2018 IPR004378 F420H(2)-dependent quinone reductase GO:0016491|GO:0055114 CNX65_RS18830 1856e9878dd9577ddcfe687e3d85112b 274 Pfam PF01814 Hemerythrin HHE cation binding domain 152 273 2.9E-18 T 28-03-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 CNX65_RS23920 0a5bf486107d2a9858ad8814a74d7b0b 598 SUPERFAMILY SSF55874 241 359 2.05E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS23920 0a5bf486107d2a9858ad8814a74d7b0b 598 SMART SM00387 248 359 9.2E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS23920 0a5bf486107d2a9858ad8814a74d7b0b 598 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 251 357 3.9E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS23920 0a5bf486107d2a9858ad8814a74d7b0b 598 Gene3D G3DSA:3.30.565.10 143 358 9.8E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16655 1860da5c5f5be5ffca817171c84dc9be 222 Pfam PF13349 Putative adhesin 20 219 1.0E-11 T 28-03-2018 IPR025164 Putative adhesin CNX65_RS08145 11979571806fb64eb176b0d65db1485f 418 SUPERFAMILY SSF55874 287 392 9.9E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS08145 11979571806fb64eb176b0d65db1485f 418 Pfam PF07730 Histidine kinase 204 268 3.9E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS08145 11979571806fb64eb176b0d65db1485f 418 Gene3D G3DSA:3.30.565.10 272 398 4.4E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07400 71cde6160a46eecdd69a39b12807d907 141 SUPERFAMILY SSF69500 2 140 8.37E-41 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CNX65_RS07400 71cde6160a46eecdd69a39b12807d907 141 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 141 28.42 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CNX65_RS07400 71cde6160a46eecdd69a39b12807d907 141 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 3 140 1.7E-37 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CNX65_RS07400 71cde6160a46eecdd69a39b12807d907 141 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 140 3.0E-47 T 28-03-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 CNX65_RS07400 71cde6160a46eecdd69a39b12807d907 141 Gene3D G3DSA:3.50.80.10 1 141 3.4E-48 T 28-03-2018 IPR023509 D-Tyr tRNAtyr deacylase-like domain CNX65_RS05035 6d81fd714f47e3984d49eafab4386107 425 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 135 303 3.6E-7 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CNX65_RS05035 6d81fd714f47e3984d49eafab4386107 425 SUPERFAMILY SSF54675 3 133 3.92E-39 T 28-03-2018 CNX65_RS05035 6d81fd714f47e3984d49eafab4386107 425 Gene3D G3DSA:3.20.140.10 1 365 8.0E-97 T 28-03-2018 CNX65_RS05035 6d81fd714f47e3984d49eafab4386107 425 PIRSF PIRSF000484 1 422 6.3E-96 T 28-03-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 CNX65_RS05035 6d81fd714f47e3984d49eafab4386107 425 SUPERFAMILY SSF51690 135 421 1.05E-84 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CNX65_RS05035 6d81fd714f47e3984d49eafab4386107 425 TIGRFAM TIGR01513 NAPRTase_put: nicotinate phosphoribosyltransferase 5 415 6.9E-133 T 28-03-2018 IPR006405 Nicotinate phosphoribosyltransferase pncB-type GO:0004516|GO:0019358 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264|Reactome: R-HSA-6798695 CNX65_RS07035 0662871e52c6621723bf43e9d4b92635 167 Gene3D G3DSA:1.10.10.10 2 52 3.0E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07035 0662871e52c6621723bf43e9d4b92635 167 Pfam PF02631 RecX family 29 149 2.7E-29 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CNX65_RS07035 0662871e52c6621723bf43e9d4b92635 167 Hamap MF_01114 Regulatory protein RecX [recX]. 2 154 14.278 T 28-03-2018 IPR003783 Regulatory protein RecX GO:0006282 CNX65_RS07035 0662871e52c6621723bf43e9d4b92635 167 Gene3D G3DSA:1.10.10.10 103 152 4.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07035 0662871e52c6621723bf43e9d4b92635 167 Gene3D G3DSA:1.10.10.10 53 98 5.7E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30875 6bd2e76ad4478cf40b7657e575f1ef85 358 Pfam PF00005 ABC transporter 19 163 5.1E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS30875 6bd2e76ad4478cf40b7657e575f1ef85 358 SUPERFAMILY SSF52540 1 239 8.05E-73 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30875 6bd2e76ad4478cf40b7657e575f1ef85 358 Gene3D G3DSA:3.40.50.300 1 244 7.6E-69 T 28-03-2018 CNX65_RS30875 6bd2e76ad4478cf40b7657e575f1ef85 358 SMART SM00382 27 213 5.6E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30875 6bd2e76ad4478cf40b7657e575f1ef85 358 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS08090 71f906b1abf8cfbc036436631fd9dccc 343 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 36 298 1.7E-14 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 SUPERFAMILY SSF52540 247 409 4.47E-20 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 SMART SM00670 27 154 1.9E-20 T 28-03-2018 IPR002716 PIN domain CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 Pfam PF02562 PhoH-like protein 249 453 4.8E-55 T 28-03-2018 IPR003714 PhoH-like protein GO:0005524 CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 Gene3D G3DSA:3.40.50.300 246 451 2.6E-18 T 28-03-2018 CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 SUPERFAMILY SSF88723 27 86 6.87E-11 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 SUPERFAMILY SSF88723 119 167 6.87E-11 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 Gene3D G3DSA:3.40.50.1010 26 198 1.5E-30 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS03570 5bbf2b7aca4f6fdcbe23c5dcb2a2b178 458 Pfam PF13638 PIN domain 29 167 6.7E-29 T 28-03-2018 IPR002716 PIN domain CNX65_RS07745 cc097b6153866340f8c7d8bfcf2172d6 278 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 7 177 4.4E-18 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 Gene3D G3DSA:3.30.1360.10 107 221 6.3E-27 T 28-03-2018 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 Gene3D G3DSA:3.30.1360.10 3 83 9.2E-17 T 28-03-2018 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 SUPERFAMILY SSF55257 170 220 5.1E-25 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 SUPERFAMILY SSF55257 13 48 5.1E-25 T 28-03-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 SUPERFAMILY SSF56553 48 169 1.57E-43 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 SUPERFAMILY SSF47789 246 318 1.28E-23 T 28-03-2018 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 Gene3D G3DSA:1.10.150.20 239 322 4.1E-24 T 28-03-2018 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 250 317 8.0E-30 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 243 301 4.5E-26 T 28-03-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 3 311 34.72 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 19 310 1.1E-113 T 28-03-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 57 149 1.4E-25 T 28-03-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 SMART SM00662 18 225 5.7E-97 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS32300 81ab4c6fe5c4aba2688a25baa32c6a7c 350 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 24 218 2.6E-19 T 28-03-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS12760 318480079fa6a84c517178495031e302 295 Pfam PF12852 Cupin 2 175 2.6E-43 T 28-03-2018 IPR032783 AraC-type transcription regulator, ligand-binding domain CNX65_RS12760 318480079fa6a84c517178495031e302 295 Gene3D G3DSA:2.60.120.280 12 173 8.6E-12 T 28-03-2018 CNX65_RS12760 318480079fa6a84c517178495031e302 295 SUPERFAMILY SSF46689 241 290 2.73E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12760 318480079fa6a84c517178495031e302 295 Gene3D G3DSA:1.10.10.60 174 245 6.9E-11 T 28-03-2018 CNX65_RS12760 318480079fa6a84c517178495031e302 295 Pfam PF12833 Helix-turn-helix domain 211 289 5.6E-20 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS12760 318480079fa6a84c517178495031e302 295 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 242 284 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS12760 318480079fa6a84c517178495031e302 295 SUPERFAMILY SSF46689 191 238 9.56E-8 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12760 318480079fa6a84c517178495031e302 295 Gene3D G3DSA:1.10.10.60 246 292 9.7E-12 T 28-03-2018 CNX65_RS12760 318480079fa6a84c517178495031e302 295 SMART SM00342 205 288 4.2E-31 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16620 6ffea9200eca8f45459fa059bab9702a 216 Pfam PF13026 Protein of unknown function (DUF3887) 130 211 3.8E-9 T 28-03-2018 IPR024981 Domain of unknown function DUF3887 KEGG: 00983+3.1.1.1|MetaCyc: PWY-6303|MetaCyc: PWY-6857 CNX65_RS16620 6ffea9200eca8f45459fa059bab9702a 216 Gene3D G3DSA:1.10.10.10 32 103 2.9E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20135 ca5d2ad687daab6106511724bc61153e 750 Gene3D G3DSA:1.25.40.10 540 728 0.0025 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20135 ca5d2ad687daab6106511724bc61153e 750 Gene3D G3DSA:1.25.40.120 23 538 1.5E-7 T 28-03-2018 CNX65_RS27600 ea3531dbb5ec0b0427af05252973e850 438 SUPERFAMILY SSF51695 163 426 7.06E-33 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS27600 ea3531dbb5ec0b0427af05252973e850 438 Gene3D G3DSA:3.20.20.190 158 430 3.1E-24 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS27600 ea3531dbb5ec0b0427af05252973e850 438 SUPERFAMILY SSF50370 47 138 3.86E-5 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS27600 ea3531dbb5ec0b0427af05252973e850 438 Gene3D G3DSA:2.80.10.50 27 155 1.3E-4 T 28-03-2018 CNX65_RS32835 855986c00b20d3f65b5434589f9f3756 253 Gene3D G3DSA:3.90.226.10 1 249 6.3E-57 T 28-03-2018 CNX65_RS32835 855986c00b20d3f65b5434589f9f3756 253 SUPERFAMILY SSF52096 2 244 2.31E-58 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS32835 855986c00b20d3f65b5434589f9f3756 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 226 1.5E-45 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS01435 1e902067887be3b2479ced3d48417bcb 185 Pfam PF00482 Type II secretion system (T2SS), protein F 52 170 2.6E-14 T 28-03-2018 IPR018076 Type II secretion system F domain CNX65_RS18485 d790f12dd5b704fc2ec3129505aba567 171 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 40 116 7.7E-7 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS18485 d790f12dd5b704fc2ec3129505aba567 171 Gene3D G3DSA:2.30.110.10 16 168 6.3E-17 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS18485 d790f12dd5b704fc2ec3129505aba567 171 SUPERFAMILY SSF50475 38 159 2.99E-15 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS34890 674233eb1046a5a5df7edc9c80d8c016 512 Gene3D G3DSA:3.40.50.720 2 312 7.3E-34 T 28-03-2018 CNX65_RS34890 674233eb1046a5a5df7edc9c80d8c016 512 Pfam PF13460 NAD(P)H-binding 8 114 4.0E-21 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34890 674233eb1046a5a5df7edc9c80d8c016 512 SUPERFAMILY SSF51735 3 281 6.18E-51 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS34890 674233eb1046a5a5df7edc9c80d8c016 512 Gene3D G3DSA:3.30.530.20 331 489 7.3E-7 T 28-03-2018 IPR023393 START-like domain CNX65_RS34890 674233eb1046a5a5df7edc9c80d8c016 512 Pfam PF11066 Protein of unknown function (DUF2867) 326 471 5.8E-40 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 CNX65_RS34260 017945b4403a0fd6fcfd7bf5fb07ed91 128 Pfam PF10861 Protein of Unknown function (DUF2784) 6 110 1.5E-32 T 28-03-2018 IPR021218 Protein of unknown function DUF2784 CNX65_RS30665 170e5565568e7aef8d91f90404ae36cb 533 Gene3D G3DSA:3.90.226.10 11 274 6.8E-63 T 28-03-2018 CNX65_RS30665 170e5565568e7aef8d91f90404ae36cb 533 Pfam PF01039 Carboxyl transferase domain 50 522 1.6E-151 T 28-03-2018 IPR034733 Acetyl-CoA carboxylase KEGG: 00061+6.4.1.2|KEGG: 00254+6.4.1.2|KEGG: 00620+6.4.1.2|KEGG: 00640+6.4.1.2|KEGG: 00720+6.4.1.2|MetaCyc: PWY-6679|MetaCyc: PWY-7388|Reactome: R-HSA-196780 CNX65_RS30665 170e5565568e7aef8d91f90404ae36cb 533 SUPERFAMILY SSF52096 28 272 1.44E-67 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS30665 170e5565568e7aef8d91f90404ae36cb 533 Gene3D G3DSA:3.90.226.10 275 525 2.0E-71 T 28-03-2018 CNX65_RS30665 170e5565568e7aef8d91f90404ae36cb 533 SUPERFAMILY SSF52096 239 515 9.38E-89 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS25600 20f9fa6bdd310551568c6376a19427f3 137 Gene3D G3DSA:3.10.580.10 1 134 6.2E-27 T 28-03-2018 CNX65_RS25600 20f9fa6bdd310551568c6376a19427f3 137 SMART SM00116 76 123 1.1E-8 T 28-03-2018 IPR000644 CBS domain CNX65_RS25600 20f9fa6bdd310551568c6376a19427f3 137 SMART SM00116 11 59 3.8E-8 T 28-03-2018 IPR000644 CBS domain CNX65_RS25600 20f9fa6bdd310551568c6376a19427f3 137 Pfam PF00571 CBS domain 74 123 1.6E-11 T 28-03-2018 IPR000644 CBS domain CNX65_RS25600 20f9fa6bdd310551568c6376a19427f3 137 Pfam PF00571 CBS domain 4 55 7.7E-12 T 28-03-2018 IPR000644 CBS domain CNX65_RS25600 20f9fa6bdd310551568c6376a19427f3 137 SUPERFAMILY SSF54631 2 129 7.58E-32 T 28-03-2018 CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 SUPERFAMILY SSF46894 126 203 1.8E-11 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 Pfam PF08448 PAS fold 25 129 1.4E-8 T 28-03-2018 IPR013656 PAS fold-4 CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 SUPERFAMILY SSF55785 20 120 6.77E-15 T 28-03-2018 IPR000014 PAS domain CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 SMART SM00421 139 196 2.5E-5 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 SMART SM00091 19 85 6.3E-9 T 28-03-2018 IPR000014 PAS domain CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 Gene3D G3DSA:1.10.10.10 131 208 7.6E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 Pfam PF00196 Bacterial regulatory proteins, luxR family 142 195 2.0E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 Gene3D G3DSA:3.30.450.20 3 126 9.8E-17 T 28-03-2018 CNX65_RS22525 3ba1f2b84a15140b0efa7f56e9d8f27c 217 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 116 6.2E-8 T 28-03-2018 IPR000014 PAS domain CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 Pfam PF00664 ABC transporter transmembrane region 34 304 1.4E-43 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 ProSitePatterns PS00211 ABC transporters family signature. 508 522 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 Pfam PF00005 ABC transporter 387 536 9.8E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 SMART SM00382 396 582 4.9E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 SUPERFAMILY SSF52540 350 606 1.09E-81 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 Gene3D G3DSA:3.40.50.300 344 612 6.3E-71 T 28-03-2018 CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 SUPERFAMILY SSF90123 20 342 6.54E-74 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS25500 1d25f557938d55ae56fb09d437eb06eb 644 Gene3D G3DSA:1.20.1560.10 11 339 1.7E-69 T 28-03-2018 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 PRINTS PR01035 Tetracycline resistance protein signature 25 41 1.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 PRINTS PR01035 Tetracycline resistance protein signature 169 189 1.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 PRINTS PR01035 Tetracycline resistance protein signature 83 107 1.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 PRINTS PR01035 Tetracycline resistance protein signature 141 163 1.6E-5 T 28-03-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 Gene3D G3DSA:1.20.1250.20 220 418 4.9E-10 T 28-03-2018 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 Gene3D G3DSA:1.20.1250.20 17 199 4.5E-21 T 28-03-2018 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 Pfam PF07690 Major Facilitator Superfamily 22 369 3.1E-29 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS22900 c87dbeef79b0bad32fa22b978c25c359 419 SUPERFAMILY SSF103473 18 406 7.19E-36 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS26285 978ba8790c0f7feb513a8ef800a6b7e1 111 Pfam PF03551 Transcriptional regulator PadR-like family 17 84 1.1E-10 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS26285 978ba8790c0f7feb513a8ef800a6b7e1 111 Gene3D G3DSA:1.10.10.10 1 105 8.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26285 978ba8790c0f7feb513a8ef800a6b7e1 111 SUPERFAMILY SSF46785 8 88 4.89E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28175 96618b71aefd606acb53f96a374a3cf7 492 Gene3D G3DSA:3.30.70.1450 392 477 1.7E-13 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS28175 96618b71aefd606acb53f96a374a3cf7 492 SUPERFAMILY SSF116726 402 471 5.49E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS28175 96618b71aefd606acb53f96a374a3cf7 492 Pfam PF00999 Sodium/hydrogen exchanger family 14 380 1.2E-45 T 28-03-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 CNX65_RS28175 96618b71aefd606acb53f96a374a3cf7 492 Pfam PF02080 TrkA-C domain 408 468 2.7E-10 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS15210 bebc813e933d81d92c52381096039d05 276 SUPERFAMILY SSF54506 5 274 2.16E-63 T 28-03-2018 CNX65_RS15210 bebc813e933d81d92c52381096039d05 276 Gene3D G3DSA:3.10.310.10 130 263 3.4E-24 T 28-03-2018 CNX65_RS15210 bebc813e933d81d92c52381096039d05 276 Gene3D G3DSA:3.10.310.10 2 129 2.2E-29 T 28-03-2018 CNX65_RS15210 bebc813e933d81d92c52381096039d05 276 Pfam PF02567 Phenazine biosynthesis-like protein 8 271 1.9E-41 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CNX65_RS15210 bebc813e933d81d92c52381096039d05 276 PIRSF PIRSF016184 1 275 8.2E-58 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CNX65_RS15210 bebc813e933d81d92c52381096039d05 276 TIGRFAM TIGR00654 PhzF_family: phenazine biosynthesis protein, PhzF family 5 274 1.9E-40 T 28-03-2018 IPR003719 Phenazine biosynthesis PhzF protein GO:0003824|GO:0009058 CNX65_RS21515 dd7aa97c77fe5849bc05c1c518c4f3de 346 Pfam PF01497 Periplasmic binding protein 64 310 2.0E-32 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS21515 dd7aa97c77fe5849bc05c1c518c4f3de 346 Gene3D G3DSA:3.40.50.1980 43 172 5.9E-31 T 28-03-2018 CNX65_RS21515 dd7aa97c77fe5849bc05c1c518c4f3de 346 SUPERFAMILY SSF53807 42 312 2.32E-48 T 28-03-2018 CNX65_RS21515 dd7aa97c77fe5849bc05c1c518c4f3de 346 Gene3D G3DSA:3.40.50.1980 173 346 4.8E-24 T 28-03-2018 CNX65_RS09135 e657cfc5b3c21b1311778fff8a4558a5 378 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 55 236 7.0E-18 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS09135 e657cfc5b3c21b1311778fff8a4558a5 378 SMART SM00637 281 375 9.8E-20 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS09135 e657cfc5b3c21b1311778fff8a4558a5 378 SUPERFAMILY SSF52266 43 246 1.97E-33 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS09135 e657cfc5b3c21b1311778fff8a4558a5 378 Pfam PF00553 Cellulose binding domain 281 372 1.4E-18 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS09135 e657cfc5b3c21b1311778fff8a4558a5 378 Gene3D G3DSA:3.40.50.1110 45 265 1.1E-32 T 28-03-2018 CNX65_RS09135 e657cfc5b3c21b1311778fff8a4558a5 378 SUPERFAMILY SSF49384 275 376 1.05E-23 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS09135 e657cfc5b3c21b1311778fff8a4558a5 378 Gene3D G3DSA:2.60.40.290 270 377 5.3E-25 T 28-03-2018 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 SUPERFAMILY SSF47203 223 356 6.28E-15 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 Gene3D G3DSA:1.20.140.10 205 372 2.8E-15 T 28-03-2018 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 5 104 7.7E-16 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 Gene3D G3DSA:1.10.540.10 2 105 1.2E-19 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 PIRSF PIRSF016578 1 367 2.1E-28 T 28-03-2018 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 SUPERFAMILY SSF56645 4 202 2.09E-33 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 Gene3D G3DSA:2.40.110.10 108 204 7.9E-7 T 28-03-2018 CNX65_RS22750 afb142a074c8553ac68e0717016a3890 380 Pfam PF08028 Acyl-CoA dehydrogenase, C-terminal domain 231 354 2.9E-11 T 28-03-2018 IPR013107 Acyl-CoA dehydrogenase, C-terminal domain CNX65_RS07780 fe7f1cf3048365102528107c43370b31 316 Pfam PF06089 L-asparaginase II 7 309 1.1E-114 T 28-03-2018 IPR010349 L-asparaginase II CNX65_RS07780 fe7f1cf3048365102528107c43370b31 316 Gene3D G3DSA:3.40.710.10 14 254 0.0013 T 28-03-2018 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 319 334 1.2E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 214 229 1.2E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 166 181 1.2E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 PRINTS PR00756 Membrane alanyl dipeptidase (M1) family signature 338 350 1.2E-10 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 SUPERFAMILY SSF63737 37 230 2.35E-32 T 28-03-2018 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 Gene3D G3DSA:1.10.390.10 313 463 1.7E-34 T 28-03-2018 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 SUPERFAMILY SSF55486 259 466 1.01E-49 T 28-03-2018 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 Pfam PF01433 Peptidase family M1 domain 312 459 1.2E-25 T 28-03-2018 IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal GO:0008237|GO:0008270 CNX65_RS33030 e020519ed6e144a700e617b7489b6ed4 512 Gene3D G3DSA:2.60.40.1730 48 232 1.4E-35 T 28-03-2018 CNX65_RS32325 2b40ccf80060da414bfd87960cf34569 73 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 4 72 2.9E-38 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CNX65_RS32325 2b40ccf80060da414bfd87960cf34569 73 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 2 73 26.567 T 28-03-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 CNX65_RS32325 2b40ccf80060da414bfd87960cf34569 73 SUPERFAMILY SSF50249 4 72 3.94E-27 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS32325 2b40ccf80060da414bfd87960cf34569 73 Gene3D G3DSA:2.40.50.140 1 73 1.5E-37 T 28-03-2018 CNX65_RS32325 2b40ccf80060da414bfd87960cf34569 73 Pfam PF01176 Translation initiation factor 1A / IF-1 8 71 2.3E-29 T 28-03-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 CNX65_RS25305 af0bd1189e1a879ccca32f8e42ea59f5 108 Gene3D G3DSA:3.30.750.24 1 108 2.9E-22 T 28-03-2018 IPR002645 STAS domain CNX65_RS25305 af0bd1189e1a879ccca32f8e42ea59f5 108 Pfam PF13466 STAS domain 16 92 2.8E-13 T 28-03-2018 IPR002645 STAS domain CNX65_RS25305 af0bd1189e1a879ccca32f8e42ea59f5 108 SUPERFAMILY SSF52091 6 108 1.12E-22 T 28-03-2018 IPR002645 STAS domain CNX65_RS25305 af0bd1189e1a879ccca32f8e42ea59f5 108 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 1 105 4.7E-20 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS20555 c28a0befbdcb2df52a5b84d28b0ca790 232 SUPERFAMILY SSF48498 85 191 2.06E-21 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS20555 c28a0befbdcb2df52a5b84d28b0ca790 232 Pfam PF13305 WHG domain 88 172 4.2E-12 T 28-03-2018 IPR025996 WHG domain CNX65_RS20555 c28a0befbdcb2df52a5b84d28b0ca790 232 Gene3D G3DSA:1.10.10.60 6 62 2.9E-16 T 28-03-2018 CNX65_RS20555 c28a0befbdcb2df52a5b84d28b0ca790 232 SUPERFAMILY SSF46689 4 85 2.34E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS20555 c28a0befbdcb2df52a5b84d28b0ca790 232 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 60 1.6E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS20555 c28a0befbdcb2df52a5b84d28b0ca790 232 Gene3D G3DSA:1.10.357.10 63 196 9.0E-23 T 28-03-2018 CNX65_RS21240 712f7240903a8316e45e567fc72ae6c1 255 Gene3D G3DSA:1.10.3720.10 45 251 1.8E-31 T 28-03-2018 CNX65_RS21240 712f7240903a8316e45e567fc72ae6c1 255 SUPERFAMILY SSF161098 4 253 1.18E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS21240 712f7240903a8316e45e567fc72ae6c1 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 73 249 2.0E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS17320 06ca41d2f55503a141813137f77c6e11 89 SUPERFAMILY SSF143011 10 89 3.73E-9 T 28-03-2018 IPR035095 Toxin RelE-like domain CNX65_RS17320 06ca41d2f55503a141813137f77c6e11 89 Gene3D G3DSA:3.30.2310.20 2 89 7.1E-8 T 28-03-2018 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 224 380 2.7E-18 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 Gene3D G3DSA:1.10.540.10 3 114 9.8E-21 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 Gene3D G3DSA:1.20.140.10 214 386 2.2E-23 T 28-03-2018 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 113 1.4E-13 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 211 8.0E-16 T 28-03-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 Gene3D G3DSA:2.40.110.10 118 213 7.9E-29 T 28-03-2018 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 SUPERFAMILY SSF56645 6 222 1.57E-52 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS23380 0cc3333f494a527a5fc5e8d7d49a190b 390 SUPERFAMILY SSF47203 222 382 4.83E-22 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS19005 4d1e49313eb8d7339fb9aa02fccf5e20 330 SUPERFAMILY SSF48576 3 286 1.78E-23 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS19005 4d1e49313eb8d7339fb9aa02fccf5e20 330 Gene3D G3DSA:1.10.600.10 1 292 4.6E-38 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS14680 be5d484642bc4400cfcb8921699ca1fd 135 Gene3D G3DSA:3.40.50.2300 2 135 1.4E-26 T 28-03-2018 CNX65_RS14680 be5d484642bc4400cfcb8921699ca1fd 135 Pfam PF00072 Response regulator receiver domain 8 121 2.1E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS14680 be5d484642bc4400cfcb8921699ca1fd 135 SMART SM00448 5 123 5.2E-19 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS14680 be5d484642bc4400cfcb8921699ca1fd 135 SUPERFAMILY SSF52172 7 131 2.99E-26 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS00315 9de43253cb1556323025daaf680fda2c 141 Pfam PF02566 OsmC-like protein 44 136 9.5E-19 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS00315 9de43253cb1556323025daaf680fda2c 141 TIGRFAM TIGR03562 osmo_induc_OsmC: peroxiredoxin, OsmC subfamily 5 138 1.2E-52 T 28-03-2018 IPR019904 Peroxiredoxin OsmC GO:0004601|GO:0006979 KEGG: 00480+1.11.1.15 CNX65_RS00315 9de43253cb1556323025daaf680fda2c 141 Gene3D G3DSA:3.30.300.20 7 141 1.3E-29 T 28-03-2018 IPR015946 K homology domain-like, alpha/beta CNX65_RS00315 9de43253cb1556323025daaf680fda2c 141 SUPERFAMILY SSF82784 4 135 1.7E-32 T 28-03-2018 IPR003718 OsmC/Ohr family CNX65_RS07085 2f294e85f58e1ba61a3d350ee23a23e0 97 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 13 26 7.5E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07085 2f294e85f58e1ba61a3d350ee23a23e0 97 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 2 13 7.5E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07085 2f294e85f58e1ba61a3d350ee23a23e0 97 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 36 56 7.5E-6 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07085 2f294e85f58e1ba61a3d350ee23a23e0 97 SMART SM00422 1 69 2.2E-10 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07085 2f294e85f58e1ba61a3d350ee23a23e0 97 Pfam PF13411 MerR HTH family regulatory protein 3 64 1.9E-13 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS07085 2f294e85f58e1ba61a3d350ee23a23e0 97 Gene3D G3DSA:1.10.1660.10 1 97 4.6E-17 T 28-03-2018 CNX65_RS07085 2f294e85f58e1ba61a3d350ee23a23e0 97 SUPERFAMILY SSF46955 3 90 1.72E-19 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS19870 7721f9d4e183ea3c3868236d5e76aaf8 190 SUPERFAMILY SSF109604 11 121 2.92E-14 T 28-03-2018 CNX65_RS19870 7721f9d4e183ea3c3868236d5e76aaf8 190 Gene3D G3DSA:1.10.3210.10 8 188 2.2E-13 T 28-03-2018 CNX65_RS19870 7721f9d4e183ea3c3868236d5e76aaf8 190 SMART SM00471 16 184 9.0E-4 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS19870 7721f9d4e183ea3c3868236d5e76aaf8 190 Pfam PF01966 HD domain 20 104 5.9E-8 T 28-03-2018 IPR006674 HD domain CNX65_RS06730 24caff78b8f226914d065a3edcfb02ec 328 SUPERFAMILY SSF51430 1 316 3.8E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS06730 24caff78b8f226914d065a3edcfb02ec 328 PRINTS PR00069 Aldo-keto reductase signature 247 271 6.3E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS06730 24caff78b8f226914d065a3edcfb02ec 328 PRINTS PR00069 Aldo-keto reductase signature 40 64 6.3E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS06730 24caff78b8f226914d065a3edcfb02ec 328 PRINTS PR00069 Aldo-keto reductase signature 106 124 6.3E-7 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS06730 24caff78b8f226914d065a3edcfb02ec 328 Pfam PF00248 Aldo/keto reductase family 15 314 5.3E-75 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS06730 24caff78b8f226914d065a3edcfb02ec 328 Gene3D G3DSA:3.20.20.100 3 317 1.8E-95 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS02420 9049525c4358efd85fb79c0e7a4cab3f 124 Pfam PF03733 Inner membrane component domain 4 54 2.2E-18 T 28-03-2018 IPR005185 Inner membrane component domain CNX65_RS02420 9049525c4358efd85fb79c0e7a4cab3f 124 Pfam PF03733 Inner membrane component domain 68 118 9.9E-19 T 28-03-2018 IPR005185 Inner membrane component domain CNX65_RS02420 9049525c4358efd85fb79c0e7a4cab3f 124 PIRSF PIRSF028777 1 124 1.9E-51 T 28-03-2018 IPR031308 Uncharacterised conserved protein UCP028777 CNX65_RS26550 fc30b8ef1bbb500835576184b656723b 302 Gene3D G3DSA:3.30.2350.10 91 295 6.0E-46 T 28-03-2018 CNX65_RS26550 fc30b8ef1bbb500835576184b656723b 302 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 138 152 - T 28-03-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS26550 fc30b8ef1bbb500835576184b656723b 302 SUPERFAMILY SSF55120 85 296 5.6E-50 T 28-03-2018 IPR020103 Pseudouridine synthase, catalytic domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS26550 fc30b8ef1bbb500835576184b656723b 302 Pfam PF00849 RNA pseudouridylate synthase 100 245 2.5E-17 T 28-03-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 17 25 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 Gene3D G3DSA:3.40.50.620 2 178 5.5E-18 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 SUPERFAMILY SSF52402 4 185 1.54E-30 T 28-03-2018 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 TIGRFAM TIGR00032 argG: argininosuccinate synthase 13 419 5.4E-139 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 129 140 - T 28-03-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 Pfam PF00764 Arginosuccinate synthase 16 404 4.4E-56 T 28-03-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 Hamap MF_00581 Argininosuccinate synthase [argG]. 1 472 76.855 T 28-03-2018 IPR023437 Argininosuccinate synthase, type 2 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 Gene3D G3DSA:3.90.1260.10 179 374 4.4E-56 T 28-03-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 SUPERFAMILY SSF69864 190 437 1.31E-74 T 28-03-2018 CNX65_RS10460 3e6630001a6a3b2d5849c86b9365e68b 481 Gene3D G3DSA:1.10.287.400 378 438 1.1E-30 T 28-03-2018 IPR024073 Argininosuccinate synthetase mutimerisation domain, C-terminal tail GO:0042803 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400 CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 Gene3D G3DSA:3.90.180.10 1 154 3.9E-52 T 28-03-2018 CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 Gene3D G3DSA:3.40.50.10730 155 292 8.1E-18 T 28-03-2018 CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 SUPERFAMILY SSF51735 138 299 1.86E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 Pfam PF00107 Zinc-binding dehydrogenase 171 289 2.7E-14 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 SMART SM00829 8 327 5.5E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 57 71 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 SUPERFAMILY SSF50129 2 169 2.59E-54 T 28-03-2018 IPR011032 GroES-like CNX65_RS26415 a7838705f195b036d2488ea91bc6fca1 329 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 25 130 3.1E-33 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS20685 1ff5a63c315e6bdd37255a1d9b58cb22 534 SUPERFAMILY SSF49384 436 531 7.67E-22 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS20685 1ff5a63c315e6bdd37255a1d9b58cb22 534 Pfam PF00553 Cellulose binding domain 444 527 1.4E-16 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS20685 1ff5a63c315e6bdd37255a1d9b58cb22 534 SUPERFAMILY SSF53474 105 296 1.84E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20685 1ff5a63c315e6bdd37255a1d9b58cb22 534 SMART SM00637 442 531 3.0E-23 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS20685 1ff5a63c315e6bdd37255a1d9b58cb22 534 Gene3D G3DSA:3.40.50.1820 100 417 1.9E-6 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20685 1ff5a63c315e6bdd37255a1d9b58cb22 534 Gene3D G3DSA:2.60.40.290 430 534 4.8E-25 T 28-03-2018 CNX65_RS24020 4c23679dd9a2652258774c5b4ceed4a1 196 Gene3D G3DSA:1.10.260.40 46 193 1.5E-10 T 28-03-2018 CNX65_RS24020 4c23679dd9a2652258774c5b4ceed4a1 196 SUPERFAMILY SSF46689 6 77 2.0E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS24020 4c23679dd9a2652258774c5b4ceed4a1 196 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 63 1.4E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS24020 4c23679dd9a2652258774c5b4ceed4a1 196 Gene3D G3DSA:1.10.10.60 2 45 9.1E-15 T 28-03-2018 CNX65_RS26180 38c329bedad7cfd8ff42d2a78c0f32ff 432 Pfam PF02378 Phosphotransferase system, EIIC 25 329 3.5E-70 T 28-03-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 CNX65_RS26295 51a0e7b524e21fd8573b0e2542ca7a08 123 Pfam PF14087 Domain of unknown function (DUF4267) 13 120 5.6E-22 T 28-03-2018 IPR025363 Protein of unknown function DUF4267 CNX65_RS27780 ca13c133c4c1193f50862b70ca4dcd85 384 Pfam PF00583 Acetyltransferase (GNAT) family 231 317 5.8E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS27780 ca13c133c4c1193f50862b70ca4dcd85 384 SUPERFAMILY SSF55021 4 70 2.4E-6 T 28-03-2018 CNX65_RS27780 ca13c133c4c1193f50862b70ca4dcd85 384 SUPERFAMILY SSF55729 183 326 3.9E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS27780 ca13c133c4c1193f50862b70ca4dcd85 384 Gene3D G3DSA:3.40.630.30 177 354 2.2E-22 T 28-03-2018 CNX65_RS27780 ca13c133c4c1193f50862b70ca4dcd85 384 Gene3D G3DSA:3.30.70.260 3 120 8.2E-10 T 28-03-2018 CNX65_RS09220 681d99e64649338f70a2261668ace41e 382 SUPERFAMILY SSF51604 111 379 4.19E-59 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS09220 681d99e64649338f70a2261668ace41e 382 SUPERFAMILY SSF54826 2 124 7.07E-23 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS09220 681d99e64649338f70a2261668ace41e 382 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 56 123 1.1E-7 T 28-03-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain CNX65_RS09220 681d99e64649338f70a2261668ace41e 382 Gene3D G3DSA:3.30.390.10 1 128 4.5E-27 T 28-03-2018 IPR029017 Enolase N-terminal domain-like KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 CNX65_RS09220 681d99e64649338f70a2261668ace41e 382 SMART SM00922 148 251 1.9E-20 T 28-03-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal CNX65_RS09220 681d99e64649338f70a2261668ace41e 382 Pfam PF13378 Enolase C-terminal domain-like 151 372 1.2E-47 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS09220 681d99e64649338f70a2261668ace41e 382 Gene3D G3DSA:3.20.20.120 129 382 1.2E-49 T 28-03-2018 IPR029065 Enolase C-terminal domain-like CNX65_RS11180 d92b2dc4957cc0e56864ff39470ea620 461 Gene3D G3DSA:3.40.50.300 44 263 4.5E-14 T 28-03-2018 CNX65_RS11180 d92b2dc4957cc0e56864ff39470ea620 461 SUPERFAMILY SSF52540 40 341 6.54E-24 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11180 d92b2dc4957cc0e56864ff39470ea620 461 Pfam PF00158 Sigma-54 interaction domain 168 226 1.6E-4 T 28-03-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 CNX65_RS16755 77911fcfbc2bcccce75b229e186a420b 106 Pfam PF01638 HxlR-like helix-turn-helix 5 91 1.9E-20 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS16755 77911fcfbc2bcccce75b229e186a420b 106 SUPERFAMILY SSF46785 2 97 4.66E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16755 77911fcfbc2bcccce75b229e186a420b 106 Gene3D G3DSA:1.10.10.10 2 97 3.5E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 191 0.0076 T 28-03-2018 CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 73 84 5.7E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 5.7E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 5.7E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 5.7E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 156 175 5.7E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 Gene3D G3DSA:3.40.50.720 1 250 5.4E-54 T 28-03-2018 CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 143 171 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 156 175 9.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 9.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 73 84 9.1E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 SUPERFAMILY SSF51735 6 246 4.16E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00255 8abe27bd0345cf9bddc09e5674949b0c 250 Pfam PF00106 short chain dehydrogenase 7 199 1.0E-39 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04075 7280bbae1b7c1bba36c6d1c265eee77f 75 Pfam PF11305 Protein of unknown function (DUF3107) 1 73 1.4E-27 T 28-03-2018 IPR021456 Protein of unknown function DUF3107 CNX65_RS15030 9b24c101ba82b81c7005c0fe6f78e5c0 270 SUPERFAMILY SSF161098 3 270 6.64E-61 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS15030 9b24c101ba82b81c7005c0fe6f78e5c0 270 Gene3D G3DSA:1.10.3720.10 4 263 2.5E-34 T 28-03-2018 CNX65_RS15030 9b24c101ba82b81c7005c0fe6f78e5c0 270 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 96 265 6.6E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS10145 7cf2ef43ccf193b3d080dd4ff886ccf9 508 Pfam PF01580 FtsK/SpoIIIE family 148 319 1.8E-8 T 28-03-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 CNX65_RS10145 7cf2ef43ccf193b3d080dd4ff886ccf9 508 Gene3D G3DSA:3.40.50.300 109 370 4.0E-12 T 28-03-2018 CNX65_RS10145 7cf2ef43ccf193b3d080dd4ff886ccf9 508 SUPERFAMILY SSF52540 121 340 1.05E-15 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS00075 fcdde0655528f42ac5160e232d1ec46c 298 Pfam PF01694 Rhomboid family 130 262 1.6E-32 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS00075 fcdde0655528f42ac5160e232d1ec46c 298 SUPERFAMILY SSF144091 83 266 1.83E-40 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS00075 fcdde0655528f42ac5160e232d1ec46c 298 Gene3D G3DSA:1.20.1540.10 80 266 6.6E-40 T 28-03-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 CNX65_RS21765 402cd3db8e209688bb71a46747e2758d 152 SMART SM00347 34 130 7.1E-4 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS21765 402cd3db8e209688bb71a46747e2758d 152 Pfam PF12802 MarR family 38 94 5.0E-8 T 28-03-2018 CNX65_RS21765 402cd3db8e209688bb71a46747e2758d 152 SUPERFAMILY SSF46785 23 143 2.38E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21765 402cd3db8e209688bb71a46747e2758d 152 Gene3D G3DSA:1.10.10.10 2 149 1.2E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04735 cb4de0e1ef0878d91d935029d2e073d1 237 SUPERFAMILY SSF53300 11 142 7.57E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS04735 cb4de0e1ef0878d91d935029d2e073d1 237 Gene3D G3DSA:3.40.50.410 9 202 6.2E-17 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS04735 cb4de0e1ef0878d91d935029d2e073d1 237 SMART SM00327 8 181 4.1E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS04735 cb4de0e1ef0878d91d935029d2e073d1 237 Pfam PF13519 von Willebrand factor type A domain 12 125 1.1E-11 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS16990 2eca5bb255566b2f637b592df31ada7a 212 Gene3D G3DSA:3.40.50.850 1 210 5.4E-38 T 28-03-2018 CNX65_RS16990 2eca5bb255566b2f637b592df31ada7a 212 Pfam PF00857 Isochorismatase family 7 179 4.8E-28 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS16990 2eca5bb255566b2f637b592df31ada7a 212 SUPERFAMILY SSF52499 3 186 2.49E-40 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS06620 f4e7a5fce199c9eba28f1a430f87f1e8 343 SUPERFAMILY SSF51735 1 140 4.03E-18 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06620 f4e7a5fce199c9eba28f1a430f87f1e8 343 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 118 5.8E-11 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CNX65_RS06620 f4e7a5fce199c9eba28f1a430f87f1e8 343 Gene3D G3DSA:3.40.50.720 2 115 2.5E-16 T 28-03-2018 CNX65_RS27650 dd7d74c6ca9ea3515b9fcdffda93ea14 241 Gene3D G3DSA:3.40.1800.10 106 187 1.5E-8 T 28-03-2018 CNX65_RS27650 dd7d74c6ca9ea3515b9fcdffda93ea14 241 SMART SM00507 119 176 7.0E-4 T 28-03-2018 IPR003615 HNH nuclease CNX65_RS27650 dd7d74c6ca9ea3515b9fcdffda93ea14 241 Pfam PF13391 HNH endonuclease 130 185 1.0E-7 T 28-03-2018 IPR003615 HNH nuclease CNX65_RS20355 1c91382bfc6c339bd44489201aa73d39 393 Pfam PF07690 Major Facilitator Superfamily 22 317 4.4E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS20355 1c91382bfc6c339bd44489201aa73d39 393 SUPERFAMILY SSF103473 3 372 3.66E-50 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS20355 1c91382bfc6c339bd44489201aa73d39 393 Gene3D G3DSA:1.20.1250.20 2 182 2.5E-21 T 28-03-2018 CNX65_RS20355 1c91382bfc6c339bd44489201aa73d39 393 Gene3D G3DSA:1.20.1250.20 183 389 6.1E-18 T 28-03-2018 CNX65_RS29105 7e710dc5ba96bee1682e20569b1e5ca6 353 Pfam PF01979 Amidohydrolase family 161 352 1.8E-13 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS29105 7e710dc5ba96bee1682e20569b1e5ca6 353 Gene3D G3DSA:2.30.40.10 4 57 2.3E-5 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS29105 7e710dc5ba96bee1682e20569b1e5ca6 353 SUPERFAMILY SSF51556 43 316 4.66E-60 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS29105 7e710dc5ba96bee1682e20569b1e5ca6 353 Gene3D G3DSA:3.20.20.140 58 315 8.1E-34 T 28-03-2018 CNX65_RS34810 ffe37c3b77ce094a9871f30641f84d9c 124 Pfam PF01740 STAS domain 50 113 9.7E-11 T 28-03-2018 IPR002645 STAS domain CNX65_RS34810 ffe37c3b77ce094a9871f30641f84d9c 124 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 15 112 3.5E-17 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS34810 ffe37c3b77ce094a9871f30641f84d9c 124 Gene3D G3DSA:3.30.750.24 4 119 4.0E-17 T 28-03-2018 IPR002645 STAS domain CNX65_RS34810 ffe37c3b77ce094a9871f30641f84d9c 124 SUPERFAMILY SSF52091 15 115 2.35E-19 T 28-03-2018 IPR002645 STAS domain CNX65_RS11740 4edc0c1d97a2f4e7de137d4965251bc7 338 Pfam PF14518 Iron-containing redox enzyme 142 312 4.5E-47 T 28-03-2018 IPR028201 PqqC-like protein CNX65_RS11740 4edc0c1d97a2f4e7de137d4965251bc7 338 SUPERFAMILY SSF48613 132 289 6.12E-12 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS11740 4edc0c1d97a2f4e7de137d4965251bc7 338 SMART SM01236 173 278 3.3E-38 T 28-03-2018 CNX65_RS11740 4edc0c1d97a2f4e7de137d4965251bc7 338 Gene3D G3DSA:1.20.910.10 129 338 2.2E-29 T 28-03-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 CNX65_RS12900 96261dd9811f2e44c0c41f6f27632d17 318 Gene3D G3DSA:3.40.109.30 4 86 8.8E-14 T 28-03-2018 CNX65_RS12900 96261dd9811f2e44c0c41f6f27632d17 318 SUPERFAMILY SSF55469 6 80 1.7E-9 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS12900 96261dd9811f2e44c0c41f6f27632d17 318 Gene3D G3DSA:3.40.109.10 100 317 1.1E-28 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS12900 96261dd9811f2e44c0c41f6f27632d17 318 Pfam PF00881 Nitroreductase family 115 288 7.8E-6 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS12900 96261dd9811f2e44c0c41f6f27632d17 318 SUPERFAMILY SSF55469 227 315 8.71E-11 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS12900 96261dd9811f2e44c0c41f6f27632d17 318 SUPERFAMILY SSF55469 109 170 8.71E-11 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS16840 520b5681e6286e7e1faf4e3b90242692 368 SMART SM00387 275 366 0.0094 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16840 520b5681e6286e7e1faf4e3b90242692 368 Gene3D G3DSA:3.30.565.10 241 365 1.6E-18 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16840 520b5681e6286e7e1faf4e3b90242692 368 SUPERFAMILY SSF55874 247 363 7.89E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16840 520b5681e6286e7e1faf4e3b90242692 368 Pfam PF07730 Histidine kinase 162 228 2.1E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS16840 520b5681e6286e7e1faf4e3b90242692 368 Pfam PF13581 Histidine kinase-like ATPase domain 248 329 6.6E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS32770 1e820e7265a53c2a24c595f3e4437a85 513 Pfam PF13148 Protein of unknown function (DUF3987) 61 423 3.1E-98 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) CNX65_RS14715 d82850c217d216cecfa3baa49ff36f08 310 Gene3D G3DSA:1.10.3720.10 76 309 1.5E-50 T 28-03-2018 CNX65_RS14715 d82850c217d216cecfa3baa49ff36f08 310 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 307 1.3E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14715 d82850c217d216cecfa3baa49ff36f08 310 Gene3D G3DSA:1.20.58.370 15 61 6.2E-5 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CNX65_RS14715 d82850c217d216cecfa3baa49ff36f08 310 SUPERFAMILY SSF161098 71 297 2.62E-65 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS16370 5a10728dea9e630041201590b07506a7 250 Gene3D G3DSA:2.60.130.10 14 239 2.8E-46 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS16370 5a10728dea9e630041201590b07506a7 250 Pfam PF00775 Dioxygenase 55 157 3.8E-11 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CNX65_RS16370 5a10728dea9e630041201590b07506a7 250 SUPERFAMILY SSF49482 28 215 1.57E-41 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 65 133 5.8E-29 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 SMART SM00899 152 229 0.002 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 Gene3D G3DSA:2.30.30.90 130 229 1.7E-22 T 28-03-2018 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 62 2.5E-21 T 28-03-2018 IPR022687 DTXR-type HTH domain GO:0003677 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 Gene3D G3DSA:1.10.60.10 75 129 1.3E-25 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 Gene3D G3DSA:1.10.10.10 1 73 1.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 SUPERFAMILY SSF47979 65 137 1.96E-26 T 28-03-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 SMART SM00529 26 125 7.6E-44 T 28-03-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 Pfam PF04023 FeoA domain 162 228 4.8E-8 T 28-03-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 SUPERFAMILY SSF46785 2 62 4.12E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07265 00bf91c611e33c2b186e15ec0d1922a5 230 SUPERFAMILY SSF50037 130 228 2.52E-21 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CNX65_RS13185 c5dfeb563d86400f7508816065dee9d6 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 65 3.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13185 c5dfeb563d86400f7508816065dee9d6 215 SUPERFAMILY SSF46689 8 86 1.08E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS13185 c5dfeb563d86400f7508816065dee9d6 215 Gene3D G3DSA:1.10.357.10 14 215 6.2E-30 T 28-03-2018 CNX65_RS13560 0e5057e5b64f334695d1a198672777a8 279 SMART SM00824 Thioesterase 55 271 0.0064 T 28-03-2018 IPR020802 Polyketide synthase, thioesterase domain GO:0009058|GO:0016788 CNX65_RS13560 0e5057e5b64f334695d1a198672777a8 279 SUPERFAMILY SSF53474 36 275 6.54E-50 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS13560 0e5057e5b64f334695d1a198672777a8 279 Pfam PF00975 Thioesterase domain 53 266 4.5E-52 T 28-03-2018 IPR001031 Thioesterase GO:0009058|GO:0016788 Reactome: R-HSA-75105 CNX65_RS13560 0e5057e5b64f334695d1a198672777a8 279 Gene3D G3DSA:3.40.50.1820 33 278 5.4E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00463 E-class P450 group I signature 272 298 7.4E-24 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00463 E-class P450 group I signature 389 399 7.4E-24 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00463 E-class P450 group I signature 37 56 7.4E-24 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00463 E-class P450 group I signature 354 378 7.4E-24 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00463 E-class P450 group I signature 252 269 7.4E-24 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00463 E-class P450 group I signature 399 422 7.4E-24 T 28-03-2018 IPR002401 Cytochrome P450, E-class, group I GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 Pfam PF00067 Cytochrome P450 26 431 8.3E-80 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 Gene3D G3DSA:1.10.630.10 2 452 1.8E-116 T 28-03-2018 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 392 401 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00385 P450 superfamily signature 315 326 5.2E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00385 P450 superfamily signature 390 399 5.2E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00385 P450 superfamily signature 263 280 5.2E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 PRINTS PR00385 P450 superfamily signature 399 410 5.2E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20540 7192bed238a5779c706584bfed286cf1 452 SUPERFAMILY SSF48264 5 450 1.26E-107 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS02980 e529082d0878f72d2f7c429ec7bf39df 967 SUPERFAMILY SSF56235 404 857 1.59E-93 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS02980 e529082d0878f72d2f7c429ec7bf39df 967 SUPERFAMILY SSF56235 135 339 1.59E-93 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS02980 e529082d0878f72d2f7c429ec7bf39df 967 Gene3D G3DSA:3.60.20.10 412 949 2.1E-65 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS02980 e529082d0878f72d2f7c429ec7bf39df 967 Gene3D G3DSA:1.10.287.150 306 347 1.8E-19 T 28-03-2018 CNX65_RS02980 e529082d0878f72d2f7c429ec7bf39df 967 Gene3D G3DSA:1.10.439.10 132 305 5.7E-34 T 28-03-2018 IPR023343 Penicillin amidase type, domain1 GO:0016811 CNX65_RS02980 e529082d0878f72d2f7c429ec7bf39df 967 Pfam PF01804 Penicillin amidase 136 928 1.4E-122 T 28-03-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 CNX65_RS17855 6c4c69a3a72902e62cbf3a6fb2363de5 321 SUPERFAMILY SSF51430 2 308 1.31E-87 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS17855 6c4c69a3a72902e62cbf3a6fb2363de5 321 Pfam PF00248 Aldo/keto reductase family 15 307 5.6E-62 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS17855 6c4c69a3a72902e62cbf3a6fb2363de5 321 Gene3D G3DSA:3.20.20.100 1 312 1.7E-81 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS34235 fd9cf4b83ec70713d38d1fc80b1a761a 211 SUPERFAMILY SSF52540 20 179 4.79E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34235 fd9cf4b83ec70713d38d1fc80b1a761a 211 Gene3D G3DSA:3.40.50.300 22 210 1.4E-31 T 28-03-2018 CNX65_RS34235 fd9cf4b83ec70713d38d1fc80b1a761a 211 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 26 82 8.1E-5 T 28-03-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0008152|GO:0016301 Reactome: R-HSA-73614 CNX65_RS34780 879953b2c31bad0c8ddaac257819f028 115 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 19.852 T 28-03-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 CNX65_RS34780 879953b2c31bad0c8ddaac257819f028 115 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 1.7E-21 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34780 879953b2c31bad0c8ddaac257819f028 115 SUPERFAMILY SSF54995 1 96 1.44E-28 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS34780 879953b2c31bad0c8ddaac257819f028 115 Gene3D G3DSA:3.30.70.60 1 101 1.8E-24 T 28-03-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 CNX65_RS34780 879953b2c31bad0c8ddaac257819f028 115 Pfam PF01250 Ribosomal protein S6 3 92 2.4E-23 T 28-03-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05390 56a23fc4c998636d0721a9e666ad3b8b 390 Gene3D G3DSA:3.20.20.70 26 388 6.9E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS05390 56a23fc4c998636d0721a9e666ad3b8b 390 PIRSF PIRSF000138 25 388 4.2E-121 T 28-03-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 CNX65_RS05390 56a23fc4c998636d0721a9e666ad3b8b 390 ProSitePatterns PS00557 FMN-dependent alpha-hydroxy acid dehydrogenases active site. 282 288 - T 28-03-2018 IPR008259 FMN-dependent alpha-hydroxy acid dehydrogenase, active site GO:0016491|GO:0055114 CNX65_RS05390 56a23fc4c998636d0721a9e666ad3b8b 390 Pfam PF01070 FMN-dependent dehydrogenase 35 385 2.4E-123 T 28-03-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 CNX65_RS05390 56a23fc4c998636d0721a9e666ad3b8b 390 SUPERFAMILY SSF51395 31 384 6.72E-91 T 28-03-2018 CNX65_RS29535 01073d5274466244d3706ab20ea420a2 220 SUPERFAMILY SSF55781 49 220 8.34E-38 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS29535 01073d5274466244d3706ab20ea420a2 220 SUPERFAMILY SSF46785 3 60 4.25E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29535 01073d5274466244d3706ab20ea420a2 220 Gene3D G3DSA:3.30.450.40 54 220 1.1E-37 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS29535 01073d5274466244d3706ab20ea420a2 220 SMART SM00346 1 79 6.8E-16 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS29535 01073d5274466244d3706ab20ea420a2 220 Gene3D G3DSA:1.10.10.10 1 52 1.4E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29535 01073d5274466244d3706ab20ea420a2 220 Pfam PF01614 Bacterial transcriptional regulator 111 217 2.2E-16 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS29535 01073d5274466244d3706ab20ea420a2 220 Pfam PF09339 IclR helix-turn-helix domain 2 43 1.4E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS22895 be66fcb6faa30074c6689eadd1c0d868 260 SMART SM00382 26 211 1.6E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS22895 be66fcb6faa30074c6689eadd1c0d868 260 Pfam PF00005 ABC transporter 17 162 9.6E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS22895 be66fcb6faa30074c6689eadd1c0d868 260 SUPERFAMILY SSF52540 1 224 1.52E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22895 be66fcb6faa30074c6689eadd1c0d868 260 Gene3D G3DSA:3.40.50.300 1 239 2.8E-62 T 28-03-2018 CNX65_RS09335 2c5a54f1a4ad5ebda640ac1c3d0a9782 384 SUPERFAMILY SSF51126 66 381 1.41E-14 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS09335 2c5a54f1a4ad5ebda640ac1c3d0a9782 384 Gene3D G3DSA:2.160.20.10 55 383 3.3E-13 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS09335 2c5a54f1a4ad5ebda640ac1c3d0a9782 384 SMART SM00710 135 157 550.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CNX65_RS09335 2c5a54f1a4ad5ebda640ac1c3d0a9782 384 SMART SM00710 293 315 160.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CNX65_RS09335 2c5a54f1a4ad5ebda640ac1c3d0a9782 384 SMART SM00710 188 210 700.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 SUPERFAMILY SSF46785 6 66 9.89E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 SUPERFAMILY SSF54909 71 151 1.47E-13 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 Gene3D G3DSA:3.30.70.920 59 152 8.3E-18 T 28-03-2018 CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 Pfam PF13412 Winged helix-turn-helix DNA-binding 7 53 1.5E-19 T 28-03-2018 CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 Pfam PF01037 Lrp/AsnC ligand binding domain 75 142 2.4E-12 T 28-03-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 Gene3D G3DSA:1.10.10.10 2 58 3.9E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 1.5E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 1.5E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 1.5E-18 T 28-03-2018 IPR000485 AsnC-type HTH domain GO:0043565 CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 SMART SM00344 7 116 1.4E-37 T 28-03-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 CNX65_RS12130 c6d5a3f52fe5ecb8dcb0379b10f6121d 152 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 28-03-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site CNX65_RS22800 35924c192764adfd8fed0143bd932a6c 569 SMART SM00382 343 540 1.8E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS22800 35924c192764adfd8fed0143bd932a6c 569 Gene3D G3DSA:1.20.1560.10 1 297 9.4E-11 T 28-03-2018 CNX65_RS22800 35924c192764adfd8fed0143bd932a6c 569 SUPERFAMILY SSF90123 2 289 1.57E-13 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS22800 35924c192764adfd8fed0143bd932a6c 569 Pfam PF00005 ABC transporter 334 488 3.0E-25 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS22800 35924c192764adfd8fed0143bd932a6c 569 ProSitePatterns PS00211 ABC transporters family signature. 460 474 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS22800 35924c192764adfd8fed0143bd932a6c 569 SUPERFAMILY SSF52540 311 564 4.39E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22800 35924c192764adfd8fed0143bd932a6c 569 Gene3D G3DSA:3.40.50.300 315 561 2.1E-55 T 28-03-2018 CNX65_RS05975 c60bf827db03df017952f23864a824d1 204 PIRSF PIRSF000709 3 172 2.1E-9 T 28-03-2018 CNX65_RS05975 c60bf827db03df017952f23864a824d1 204 SUPERFAMILY SSF53254 1 200 2.09E-52 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS05975 c60bf827db03df017952f23864a824d1 204 ProSitePatterns PS00175 Phosphoglycerate mutase family phosphohistidine signature. 8 17 - T 28-03-2018 IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site GO:0003824|GO:0008152 CNX65_RS05975 c60bf827db03df017952f23864a824d1 204 Gene3D G3DSA:3.40.50.1240 3 203 2.1E-49 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS05975 c60bf827db03df017952f23864a824d1 204 SMART SM00855 5 157 2.8E-21 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS05975 c60bf827db03df017952f23864a824d1 204 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 6 199 5.4E-50 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS01620 7de6d3765285f719be46cb903b60f3b7 261 Gene3D G3DSA:3.20.20.20 1 133 1.3E-50 T 28-03-2018 CNX65_RS01620 7de6d3765285f719be46cb903b60f3b7 261 Gene3D G3DSA:3.20.20.20 134 260 2.7E-49 T 28-03-2018 CNX65_RS01620 7de6d3765285f719be46cb903b60f3b7 261 SUPERFAMILY SSF51717 1 257 2.22E-88 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS01620 7de6d3765285f719be46cb903b60f3b7 261 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 34 47 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS01620 7de6d3765285f719be46cb903b60f3b7 261 Pfam PF00809 Pterin binding enzyme 1 241 1.2E-80 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS01620 7de6d3765285f719be46cb903b60f3b7 261 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 1 254 1.9E-87 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CNX65_RS17630 c165626f8397da4855fead099ded0967 274 SUPERFAMILY SSF75005 41 273 6.4E-29 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS17630 c165626f8397da4855fead099ded0967 274 Pfam PF04616 Glycosyl hydrolases family 43 39 232 2.8E-9 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS17630 c165626f8397da4855fead099ded0967 274 Gene3D G3DSA:2.115.10.20 3 54 1.5E-7 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS17630 c165626f8397da4855fead099ded0967 274 Gene3D G3DSA:2.115.10.20 172 273 3.9E-11 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS17630 c165626f8397da4855fead099ded0967 274 Gene3D G3DSA:2.115.10.20 55 171 5.3E-18 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS22135 21230baa850cdc17c32be712df42845f 197 Gene3D G3DSA:1.10.10.10 2 145 2.4E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22135 21230baa850cdc17c32be712df42845f 197 SMART SM00347 27 127 1.7E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS22135 21230baa850cdc17c32be712df42845f 197 SUPERFAMILY SSF46785 6 141 1.34E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22135 21230baa850cdc17c32be712df42845f 197 Pfam PF12802 MarR family 32 93 1.3E-11 T 28-03-2018 CNX65_RS00850 620c5e972cc965dafa9c589fec98f7d1 558 SMART SM00060 46 117 5.3E-7 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS00850 620c5e972cc965dafa9c589fec98f7d1 558 Gene3D G3DSA:2.60.40.10 38 133 7.4E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS00850 620c5e972cc965dafa9c589fec98f7d1 558 SUPERFAMILY SSF49265 39 128 1.37E-8 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS00850 620c5e972cc965dafa9c589fec98f7d1 558 Pfam PF00041 Fibronectin type III domain 47 115 8.5E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS14930 4037acc2c72e1431d5c17e159c31acd8 1099 Pfam PF13569 Domain of unknown function (DUF4132) 825 1002 9.2E-52 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS29085 eff87725e8c7c4105d1a4bf59d3fa631 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 1 244 42.718 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CNX65_RS29085 eff87725e8c7c4105d1a4bf59d3fa631 252 Pfam PF03746 LamB/YcsF family 4 239 4.3E-96 T 28-03-2018 IPR005501 Uncharacterised protein family UPF0271, LamB/YcsF CNX65_RS29085 eff87725e8c7c4105d1a4bf59d3fa631 252 Gene3D G3DSA:3.20.20.370 2 246 7.7E-101 T 28-03-2018 CNX65_RS29085 eff87725e8c7c4105d1a4bf59d3fa631 252 SUPERFAMILY SSF88713 2 245 3.11E-90 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 Gene3D G3DSA:3.30.70.1400 138 265 4.9E-21 T 28-03-2018 CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 SUPERFAMILY SSF103025 23 267 1.73E-61 T 28-03-2018 CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 23 242 7.0E-34 T 28-03-2018 IPR006222 Glycine cleavage T-protein-like, N-terminal CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 Gene3D G3DSA:2.40.30.110 267 343 9.1E-10 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 Gene3D G3DSA:3.30.1360.120 4 136 2.6E-26 T 28-03-2018 CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 TIGRFAM TIGR03317 ygfZ_signature: folate-binding protein YgfZ 214 278 8.4E-19 T 28-03-2018 IPR017703 YgfZ/GcvT conserved site CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 252 342 7.7E-6 T 28-03-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 CNX65_RS33800 5b85e1e7aaa5aaada6eafa7f47dd41b7 364 PIRSF PIRSF006487 15 348 1.6E-22 T 28-03-2018 CNX65_RS18090 ec4c5211af83e69da39cc5d27f5240a2 185 Pfam PF00196 Bacterial regulatory proteins, luxR family 125 179 7.1E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18090 ec4c5211af83e69da39cc5d27f5240a2 185 Gene3D G3DSA:1.10.10.10 17 185 6.1E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18090 ec4c5211af83e69da39cc5d27f5240a2 185 SUPERFAMILY SSF46894 116 185 1.9E-17 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS18090 ec4c5211af83e69da39cc5d27f5240a2 185 SMART SM00421 122 179 3.2E-17 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18090 ec4c5211af83e69da39cc5d27f5240a2 185 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 125 139 9.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18090 ec4c5211af83e69da39cc5d27f5240a2 185 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 155 167 9.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS18090 ec4c5211af83e69da39cc5d27f5240a2 185 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 139 155 9.2E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 Gene3D G3DSA:1.10.10.10 427 537 3.8E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 Pfam PF00270 DEAD/DEAH box helicase 27 195 1.2E-15 T 28-03-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 SMART SM00490 261 342 2.9E-24 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 Gene3D G3DSA:3.40.50.300 6 206 1.4E-27 T 28-03-2018 CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 24 355 7.9E-70 T 28-03-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 SUPERFAMILY SSF53271 568 688 5.25E-10 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 Pfam PF00271 Helicase conserved C-terminal domain 246 341 1.0E-13 T 28-03-2018 IPR001650 Helicase, C-terminal CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 SMART SM00487 20 220 8.1E-24 T 28-03-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 Pfam PF16124 RecQ zinc-binding 439 481 5.0E-6 T 28-03-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 SUPERFAMILY SSF52540 68 361 5.41E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 Gene3D G3DSA:3.40.50.300 219 370 1.1E-27 T 28-03-2018 CNX65_RS05945 03f23739a67d922e654bdef68f87be99 691 Gene3D G3DSA:3.40.50.2020 554 691 1.0E-12 T 28-03-2018 CNX65_RS01430 6235ddadede54801e98e4c43491cc442 251 Pfam PF00482 Type II secretion system (T2SS), protein F 91 205 8.4E-8 T 28-03-2018 IPR018076 Type II secretion system F domain CNX65_RS18740 4d0cadcbbaadc91c5cb72c58779bebf0 288 SUPERFAMILY SSF52091 163 273 4.71E-18 T 28-03-2018 IPR002645 STAS domain CNX65_RS18740 4d0cadcbbaadc91c5cb72c58779bebf0 288 Pfam PF14361 RsbT co-antagonist protein rsbRD N-terminal domain 15 110 5.4E-25 T 28-03-2018 IPR025751 RsbT co-antagonist protein RsbRD, N-terminal domain CNX65_RS18740 4d0cadcbbaadc91c5cb72c58779bebf0 288 Pfam PF01740 STAS domain 166 269 2.1E-10 T 28-03-2018 IPR002645 STAS domain CNX65_RS18740 4d0cadcbbaadc91c5cb72c58779bebf0 288 Gene3D G3DSA:3.30.750.24 159 282 7.1E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS13275 d5ec66654207cab2099bdcc4a85ff9fb 265 Pfam PF10021 Uncharacterized protein conserved in bacteria (DUF2263) 9 147 1.2E-44 T 28-03-2018 IPR019261 Domain of unknown function DUF2263 CNX65_RS13275 d5ec66654207cab2099bdcc4a85ff9fb 265 PIRSF PIRSF014899 1 265 2.8E-93 T 28-03-2018 IPR012664 Conserved hypothetical protein CHP02452 CNX65_RS13275 d5ec66654207cab2099bdcc4a85ff9fb 265 TIGRFAM TIGR02452 TIGR02452: TIGR02452 family protein 8 259 1.5E-76 T 28-03-2018 IPR012664 Conserved hypothetical protein CHP02452 CNX65_RS13275 d5ec66654207cab2099bdcc4a85ff9fb 265 Gene3D G3DSA:3.40.220.10 53 262 3.4E-16 T 28-03-2018 CNX65_RS13275 d5ec66654207cab2099bdcc4a85ff9fb 265 SUPERFAMILY SSF52949 190 249 1.39E-5 T 28-03-2018 CNX65_RS05760 c906838e66444de5448a1a1a03e7c7bc 196 Gene3D G3DSA:3.40.50.1820 2 191 7.3E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS05760 c906838e66444de5448a1a1a03e7c7bc 196 SUPERFAMILY SSF53474 4 186 9.6E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS05760 c906838e66444de5448a1a1a03e7c7bc 196 Pfam PF06821 Serine hydrolase 6 184 8.6E-34 T 28-03-2018 IPR010662 Putative hydrolase RBBP9/YdeN GO:0016787 CNX65_RS16545 c707679069159e6d011df179a544ac21 137 SUPERFAMILY SSF55729 10 127 6.25E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS16545 c707679069159e6d011df179a544ac21 137 Pfam PF13673 Acetyltransferase (GNAT) domain 40 127 6.5E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS16545 c707679069159e6d011df179a544ac21 137 Gene3D G3DSA:3.40.630.30 4 135 1.1E-19 T 28-03-2018 CNX65_RS26385 241164c4285e71de563b86031012db47 175 Pfam PF14430 Immunity protein Imm1 50 173 3.1E-26 T 28-03-2018 IPR025680 Immunity protein Imm1 CNX65_RS04500 854bfedcdbb1b9bd379fb5277d7350a6 378 Pfam PF01384 Phosphate transporter family 21 319 1.0E-78 T 28-03-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 CNX65_RS13140 c4775039c62cd9956d4f48d3be2cc81b 489 Pfam PF03929 PepSY-associated TM region 36 389 1.6E-67 T 28-03-2018 IPR005625 PepSY-associated TM protein CNX65_RS25190 1a54578ce18224161795259d524718cd 75 SUPERFAMILY SSF46955 10 61 2.62E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS25190 1a54578ce18224161795259d524718cd 75 Pfam PF12728 Helix-turn-helix domain 10 58 2.2E-8 T 28-03-2018 CNX65_RS25190 1a54578ce18224161795259d524718cd 75 Gene3D G3DSA:1.10.10.10 10 71 1.4E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13315 b2a518e5f6680b84587d2c76e83d257e 353 Gene3D G3DSA:3.20.20.30 3 351 1.0E-68 T 28-03-2018 CNX65_RS13315 b2a518e5f6680b84587d2c76e83d257e 353 Pfam PF00296 Luciferase-like monooxygenase 6 315 8.7E-66 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS13315 b2a518e5f6680b84587d2c76e83d257e 353 SUPERFAMILY SSF51679 6 347 5.23E-77 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS22530 a747f5fbd53efc4ec7b7b47249be1999 333 SUPERFAMILY SSF56112 9 308 4.23E-33 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS22530 a747f5fbd53efc4ec7b7b47249be1999 333 Gene3D G3DSA:3.30.200.20 2 111 4.6E-14 T 28-03-2018 CNX65_RS22530 a747f5fbd53efc4ec7b7b47249be1999 333 Pfam PF01636 Phosphotransferase enzyme family 32 287 3.4E-25 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS22530 a747f5fbd53efc4ec7b7b47249be1999 333 Gene3D G3DSA:3.90.1200.10 112 298 6.1E-21 T 28-03-2018 CNX65_RS05205 3edbf406b083da63141e88db8ba82076 596 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 468 552 6.9E-14 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CNX65_RS05205 3edbf406b083da63141e88db8ba82076 596 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 201 371 3.6E-36 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS05205 3edbf406b083da63141e88db8ba82076 596 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 201 371 4.8E-44 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS26875 a57e9f5bf31df9d10c10f6368e4e31c2 122 Pfam PF13581 Histidine kinase-like ATPase domain 11 73 7.9E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS03645 6fc6ca6f9ca388daa0a6feced3345497 382 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 245 3.6E-45 T 28-03-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 CNX65_RS03645 6fc6ca6f9ca388daa0a6feced3345497 382 Pfam PF00149 Calcineurin-like phosphoesterase 1 218 5.5E-12 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS03645 6fc6ca6f9ca388daa0a6feced3345497 382 SUPERFAMILY SSF56300 1 308 5.77E-53 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS03645 6fc6ca6f9ca388daa0a6feced3345497 382 Gene3D G3DSA:3.60.21.10 1 68 8.0E-13 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS03645 6fc6ca6f9ca388daa0a6feced3345497 382 Gene3D G3DSA:3.60.21.10 69 269 3.9E-33 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS19480 54738a4d121d2dadbe969db71805ef73 216 Gene3D G3DSA:3.40.50.720 1 216 8.1E-22 T 28-03-2018 CNX65_RS19480 54738a4d121d2dadbe969db71805ef73 216 Pfam PF13460 NAD(P)H-binding 8 201 8.0E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19480 54738a4d121d2dadbe969db71805ef73 216 SUPERFAMILY SSF51735 1 214 1.77E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16940 428753ab810fc8f5df98ff1f3af3d405 321 Gene3D G3DSA:3.40.50.720 161 256 1.5E-21 T 28-03-2018 CNX65_RS16940 428753ab810fc8f5df98ff1f3af3d405 321 SUPERFAMILY SSF51735 132 254 1.27E-23 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16940 428753ab810fc8f5df98ff1f3af3d405 321 Gene3D G3DSA:3.90.180.10 1 160 1.1E-41 T 28-03-2018 CNX65_RS16940 428753ab810fc8f5df98ff1f3af3d405 321 SMART SM00829 10 319 4.0E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS16940 428753ab810fc8f5df98ff1f3af3d405 321 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 89 3.9E-11 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS16940 428753ab810fc8f5df98ff1f3af3d405 321 Pfam PF13602 Zinc-binding dehydrogenase 202 319 2.0E-13 T 28-03-2018 CNX65_RS16940 428753ab810fc8f5df98ff1f3af3d405 321 SUPERFAMILY SSF50129 1 168 2.43E-33 T 28-03-2018 IPR011032 GroES-like CNX65_RS32530 1593f685d80d908f338da5d871bdab4a 164 Gene3D G3DSA:3.10.450.50 35 156 2.5E-5 T 28-03-2018 CNX65_RS32530 1593f685d80d908f338da5d871bdab4a 164 SUPERFAMILY SSF54427 63 155 1.23E-5 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS34320 0f9d54920814f13c91d9bb8671da91a9 143 Pfam PF13411 MerR HTH family regulatory protein 18 83 1.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS34320 0f9d54920814f13c91d9bb8671da91a9 143 SMART SM00422 16 85 1.1E-20 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS34320 0f9d54920814f13c91d9bb8671da91a9 143 SUPERFAMILY SSF46955 17 107 2.61E-18 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS34320 0f9d54920814f13c91d9bb8671da91a9 143 Gene3D G3DSA:1.10.1660.10 7 132 3.8E-22 T 28-03-2018 CNX65_RS34320 0f9d54920814f13c91d9bb8671da91a9 143 ProSitePatterns PS00552 MerR-type HTH domain signature. 19 41 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS09380 f92ea2d2a6953157fa2ab25cfbc52126 342 SUPERFAMILY SSF55874 232 336 2.88E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09380 f92ea2d2a6953157fa2ab25cfbc52126 342 Gene3D G3DSA:3.30.565.10 214 341 5.5E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09380 f92ea2d2a6953157fa2ab25cfbc52126 342 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 247 336 2.4E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS07690 59632024805cde00c0191d529cc69eaa 388 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 13 384 4.4E-112 T 28-03-2018 IPR008257 Renal dipeptidase family GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 CNX65_RS07690 59632024805cde00c0191d529cc69eaa 388 Gene3D G3DSA:3.20.20.140 4 388 3.2E-139 T 28-03-2018 CNX65_RS07690 59632024805cde00c0191d529cc69eaa 388 SUPERFAMILY SSF51556 307 386 2.38E-100 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS07690 59632024805cde00c0191d529cc69eaa 388 SUPERFAMILY SSF51556 9 268 2.38E-100 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS00865 231263f1bc6f69ffd0b696a24e52e98a 163 TIGRFAM TIGR03941 tRNA_deam_assoc: putative tRNA adenosine deaminase-associated protein 10 156 5.8E-54 T 28-03-2018 IPR023869 tRNA adenosine deaminase-associated protein, putative CNX65_RS01990 a0912a7af3f49446279dea4693846e8e 264 Pfam PF11361 Protein of unknown function (DUF3159) 18 203 4.0E-51 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CNX65_RS26065 e8735d3e23c2db6310e96527939231f1 92 Pfam PF01192 RNA polymerase Rpb6 24 86 1.3E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CNX65_RS26065 e8735d3e23c2db6310e96527939231f1 92 SMART SM01409 24 88 9.5E-15 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CNX65_RS26065 e8735d3e23c2db6310e96527939231f1 92 SUPERFAMILY SSF63562 17 88 1.92E-23 T 28-03-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CNX65_RS26065 e8735d3e23c2db6310e96527939231f1 92 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 17 87 3.4E-27 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS26065 e8735d3e23c2db6310e96527939231f1 92 Gene3D G3DSA:3.90.940.10 18 92 1.1E-20 T 28-03-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-112387|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708 CNX65_RS26065 e8735d3e23c2db6310e96527939231f1 92 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 17 89 14.444 T 28-03-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 CNX65_RS24330 5049bf66d85a67b6ed3d95e0f490d25b 221 SMART SM00448 2 113 1.2E-37 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS24330 5049bf66d85a67b6ed3d95e0f490d25b 221 Gene3D G3DSA:1.10.10.10 120 221 3.3E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24330 5049bf66d85a67b6ed3d95e0f490d25b 221 Gene3D G3DSA:3.40.50.2300 2 119 1.4E-31 T 28-03-2018 CNX65_RS24330 5049bf66d85a67b6ed3d95e0f490d25b 221 SUPERFAMILY SSF52172 3 177 3.69E-37 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS24330 5049bf66d85a67b6ed3d95e0f490d25b 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 218 4.2E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS24330 5049bf66d85a67b6ed3d95e0f490d25b 221 SMART SM00862 147 218 7.3E-27 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS24330 5049bf66d85a67b6ed3d95e0f490d25b 221 Pfam PF00072 Response regulator receiver domain 4 114 5.9E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS02210 4262e15d390603d25555807a98ac1fba 237 Pfam PF02666 Phosphatidylserine decarboxylase 60 231 3.9E-31 T 28-03-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 CNX65_RS02210 4262e15d390603d25555807a98ac1fba 237 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 26 235 36.227 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CNX65_RS02210 4262e15d390603d25555807a98ac1fba 237 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 40 234 8.3E-53 T 28-03-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 CNX65_RS06110 697856dc27e3fb9b00fd8125fdb8b990 322 Pfam PF00107 Zinc-binding dehydrogenase 167 283 4.4E-20 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS06110 697856dc27e3fb9b00fd8125fdb8b990 322 SUPERFAMILY SSF51735 128 289 1.11E-38 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06110 697856dc27e3fb9b00fd8125fdb8b990 322 Gene3D G3DSA:3.40.50.720 154 290 1.9E-28 T 28-03-2018 CNX65_RS06110 697856dc27e3fb9b00fd8125fdb8b990 322 SUPERFAMILY SSF50129 14 156 5.19E-29 T 28-03-2018 IPR011032 GroES-like CNX65_RS06110 697856dc27e3fb9b00fd8125fdb8b990 322 Gene3D G3DSA:3.90.180.10 5 153 7.9E-31 T 28-03-2018 CNX65_RS06110 697856dc27e3fb9b00fd8125fdb8b990 322 SMART SM00829 13 319 4.7E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS05770 abd690d029fd293467b48096e6897117 274 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 22 272 3.2E-52 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CNX65_RS05770 abd690d029fd293467b48096e6897117 274 Pfam PF02634 FdhD/NarQ family 26 272 3.3E-82 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CNX65_RS05770 abd690d029fd293467b48096e6897117 274 Hamap MF_00187 Sulfurtransferase FdhD [fdhD]. 2 273 34.16 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CNX65_RS05770 abd690d029fd293467b48096e6897117 274 Gene3D G3DSA:3.10.20.10 28 120 3.1E-30 T 28-03-2018 CNX65_RS05770 abd690d029fd293467b48096e6897117 274 PIRSF PIRSF015626 2 274 2.1E-88 T 28-03-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 CNX65_RS05770 abd690d029fd293467b48096e6897117 274 SUPERFAMILY SSF53927 4 272 9.02E-79 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS05770 abd690d029fd293467b48096e6897117 274 Gene3D G3DSA:3.40.140.10 136 274 1.5E-56 T 28-03-2018 CNX65_RS25640 25526f9267e4c1450ccd27ad21205755 238 SMART SM00347 9 115 0.0083 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS25640 25526f9267e4c1450ccd27ad21205755 238 Gene3D G3DSA:1.10.10.10 7 137 9.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS25640 25526f9267e4c1450ccd27ad21205755 238 Pfam PF13412 Winged helix-turn-helix DNA-binding 25 60 4.2E-7 T 28-03-2018 CNX65_RS25640 25526f9267e4c1450ccd27ad21205755 238 SUPERFAMILY SSF46785 17 203 8.51E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05200 2b4725f1826b65fb58890b4997543478 246 Pfam PF02698 DUF218 domain 76 197 3.8E-25 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CNX65_RS05200 2b4725f1826b65fb58890b4997543478 246 Gene3D G3DSA:3.40.50.620 63 198 3.7E-25 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS00845 9d80b3bdf78f3587fc4d6f70ac80c706 603 Gene3D G3DSA:2.60.40.10 61 144 3.2E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS25270 06fc0248f24331329f3d0702b888211a 238 Pfam PF00775 Dioxygenase 46 227 9.7E-53 T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CNX65_RS25270 06fc0248f24331329f3d0702b888211a 238 Gene3D G3DSA:2.60.130.10 4 235 4.2E-64 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS25270 06fc0248f24331329f3d0702b888211a 238 ProSitePatterns PS00083 Intradiol ring-cleavage dioxygenases signature. 78 106 - T 28-03-2018 IPR000627 Intradiol ring-cleavage dioxygenase, C-terminal GO:0003824|GO:0006725|GO:0008199|GO:0055114 CNX65_RS25270 06fc0248f24331329f3d0702b888211a 238 Pfam PF12391 Protocatechuate 3,4-dioxygenase beta subunit N terminal 9 42 1.6E-12 T 28-03-2018 IPR024756 Protocatechuate 3,4-dioxygenase beta subunit, N-terminal KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CNX65_RS25270 06fc0248f24331329f3d0702b888211a 238 TIGRFAM TIGR02422 protocat_beta: protocatechuate 3,4-dioxygenase, beta subunit 16 233 5.5E-102 T 28-03-2018 IPR012785 Protocatechuate 3,4-dioxygenase, beta subunit GO:0005506|GO:0018578|GO:0019619|GO:0055114 KEGG: 00362+1.13.11.3|KEGG: 00624+1.13.11.3 CNX65_RS25270 06fc0248f24331329f3d0702b888211a 238 SUPERFAMILY SSF49482 9 233 1.44E-69 T 28-03-2018 IPR015889 Intradiol ring-cleavage dioxygenase, core GO:0005506|GO:0016702|GO:0055114 CNX65_RS28870 c256f95d37eb80cf6e393b4ffee465b4 235 Gene3D G3DSA:3.40.50.1820 3 234 8.9E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS28870 c256f95d37eb80cf6e393b4ffee465b4 235 SUPERFAMILY SSF53474 7 232 1.58E-9 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20820 d28581fac62c06821eb4a8721c106113 407 SUPERFAMILY SSF89796 7 407 1.7E-132 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS20820 d28581fac62c06821eb4a8721c106113 407 Pfam PF02515 CoA-transferase family III 11 384 6.9E-127 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CNX65_RS20820 d28581fac62c06821eb4a8721c106113 407 Gene3D G3DSA:3.40.50.10540 6 407 2.3E-148 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS18865 8c317b3a0e5350c5d7f6f5475346e99b 209 Pfam PF00753 Metallo-beta-lactamase superfamily 25 188 1.3E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS18865 8c317b3a0e5350c5d7f6f5475346e99b 209 Gene3D G3DSA:3.60.15.10 19 207 1.6E-34 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS18865 8c317b3a0e5350c5d7f6f5475346e99b 209 SUPERFAMILY SSF56281 22 198 1.49E-45 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS18865 8c317b3a0e5350c5d7f6f5475346e99b 209 SMART SM00849 24 188 1.6E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS12410 724d26fd279ec7a092f90e1090491ab2 559 SUPERFAMILY SSF48264 361 549 8.64E-25 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12410 724d26fd279ec7a092f90e1090491ab2 559 SUPERFAMILY SSF48264 22 141 8.91E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS12410 724d26fd279ec7a092f90e1090491ab2 559 Gene3D G3DSA:1.10.630.10 4 507 2.4E-35 T 28-03-2018 CNX65_RS09360 da08c94912c2ce29a5999df7fba31e93 374 Gene3D G3DSA:1.20.1250.10 161 253 3.1E-4 T 28-03-2018 CNX65_RS09360 da08c94912c2ce29a5999df7fba31e93 374 Gene3D G3DSA:1.25.40.10 254 374 8.7E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS09360 da08c94912c2ce29a5999df7fba31e93 374 SUPERFAMILY SSF48452 196 358 4.75E-13 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS32775 9177df5ac82b1032ae083bf80a0b9efe 62 SUPERFAMILY SSF46955 6 56 4.03E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS32775 9177df5ac82b1032ae083bf80a0b9efe 62 Pfam PF12728 Helix-turn-helix domain 7 56 1.0E-10 T 28-03-2018 CNX65_RS32775 9177df5ac82b1032ae083bf80a0b9efe 62 Gene3D G3DSA:1.10.10.10 7 62 4.3E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19840 ca3ef0df47caaa35a330ad11739c6cea 71 Gene3D G3DSA:1.20.1630.10 4 70 3.1E-5 T 28-03-2018 CNX65_RS16060 2c3616e071b63cf2440c192c79635680 412 TIGRFAM TIGR01197 nramp: metal ion transporter, metal ion (Mn2+/Fe2+) transporter (Nramp) family 20 378 8.6E-84 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS16060 2c3616e071b63cf2440c192c79635680 412 Pfam PF01566 Natural resistance-associated macrophage protein 38 384 2.8E-106 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS16060 2c3616e071b63cf2440c192c79635680 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 97 123 5.5E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS16060 2c3616e071b63cf2440c192c79635680 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 125 144 5.5E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS16060 2c3616e071b63cf2440c192c79635680 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 300 319 5.5E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS16060 2c3616e071b63cf2440c192c79635680 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 199 222 5.5E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS16060 2c3616e071b63cf2440c192c79635680 412 PRINTS PR00447 Natural resistance-associated macrophage protein signature 151 172 5.5E-26 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 Pfam PF00082 Subtilase family 162 458 3.4E-40 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 166 177 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 211 221 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 Gene3D G3DSA:3.40.50.200 106 494 6.6E-72 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 411 421 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 SUPERFAMILY SSF52743 142 491 6.81E-67 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 PRINTS PR00723 Subtilisin serine protease family (S8) signature 161 180 8.7E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 PRINTS PR00723 Subtilisin serine protease family (S8) signature 410 426 8.7E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS05900 7f894fcb759c443078a72f7adb6ece0c 573 PRINTS PR00723 Subtilisin serine protease family (S8) signature 207 220 8.7E-19 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS22190 6e1b03ebff7f8aa01fde2926754eff50 251 Pfam PF01925 Sulfite exporter TauE/SafE 10 247 4.4E-41 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CNX65_RS14985 460ab7089c5ee76cde8be015f1531a70 162 Gene3D G3DSA:3.90.79.10 1 152 2.2E-31 T 28-03-2018 CNX65_RS14985 460ab7089c5ee76cde8be015f1531a70 162 SUPERFAMILY SSF55811 15 139 1.35E-31 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS14985 460ab7089c5ee76cde8be015f1531a70 162 ProSitePatterns PS00893 Nudix box signature. 51 72 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS14985 460ab7089c5ee76cde8be015f1531a70 162 Pfam PF00293 NUDIX domain 23 134 1.5E-19 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS24740 211eaf8f33013bc235e2d0818b667083 137 Gene3D G3DSA:3.10.129.10 1 136 3.0E-35 T 28-03-2018 CNX65_RS24740 211eaf8f33013bc235e2d0818b667083 137 SUPERFAMILY SSF54637 3 135 3.64E-37 T 28-03-2018 IPR029069 HotDog domain CNX65_RS24740 211eaf8f33013bc235e2d0818b667083 137 Pfam PF13279 Thioesterase-like superfamily 14 131 4.0E-15 T 28-03-2018 CNX65_RS31445 26745ccaab41fd60a1307a367cb02c51 153 SUPERFAMILY SSF110857 3 117 3.66E-17 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CNX65_RS31445 26745ccaab41fd60a1307a367cb02c51 153 Pfam PF13772 AIG2-like family 59 139 5.7E-20 T 28-03-2018 CNX65_RS31445 26745ccaab41fd60a1307a367cb02c51 153 Gene3D G3DSA:3.10.490.10 2 149 2.0E-33 T 28-03-2018 CNX65_RS21955 6ab2c3e92831eff6f7df75cf5fc25cf3 277 Gene3D G3DSA:3.60.130.10 1 264 1.4E-68 T 28-03-2018 CNX65_RS21955 6ab2c3e92831eff6f7df75cf5fc25cf3 277 Pfam PF02668 Taurine catabolism dioxygenase TauD, TfdA family 4 248 7.2E-57 T 28-03-2018 IPR003819 TauD/TfdA-like domain GO:0016491|GO:0055114 Reactome: R-HSA-71262 CNX65_RS21955 6ab2c3e92831eff6f7df75cf5fc25cf3 277 SUPERFAMILY SSF51197 2 256 2.11E-83 T 28-03-2018 CNX65_RS24130 4dd705f0a2643074a2cdfdc9baddd5d4 245 Gene3D G3DSA:3.40.50.300 1 218 4.5E-61 T 28-03-2018 CNX65_RS24130 4dd705f0a2643074a2cdfdc9baddd5d4 245 SMART SM00382 31 209 1.6E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS24130 4dd705f0a2643074a2cdfdc9baddd5d4 245 SUPERFAMILY SSF52540 1 230 2.46E-67 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24130 4dd705f0a2643074a2cdfdc9baddd5d4 245 Pfam PF00005 ABC transporter 22 158 8.0E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS14275 9f30faffddeb0dce2cc7248aa79eb6eb 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 32 77 6.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14275 9f30faffddeb0dce2cc7248aa79eb6eb 204 SUPERFAMILY SSF46689 18 99 1.9E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14275 9f30faffddeb0dce2cc7248aa79eb6eb 204 Gene3D G3DSA:1.10.357.10 14 204 1.1E-29 T 28-03-2018 CNX65_RS18190 0845f0364f9b19ce34f88f23961927f2 521 Pfam PF13556 PucR C-terminal helix-turn-helix domain 446 503 1.1E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS18190 0845f0364f9b19ce34f88f23961927f2 521 Gene3D G3DSA:1.10.10.60 430 481 0.0013 T 28-03-2018 CNX65_RS18190 0845f0364f9b19ce34f88f23961927f2 521 Gene3D G3DSA:3.30.450.40 116 231 3.7E-4 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14260 0cbb76f73e20e21d599194a2cd50f485 79 Gene3D G3DSA:1.10.1200.10 1 79 8.2E-16 T 28-03-2018 CNX65_RS14260 0cbb76f73e20e21d599194a2cd50f485 79 SUPERFAMILY SSF47336 3 78 2.22E-16 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS14260 0cbb76f73e20e21d599194a2cd50f485 79 Pfam PF00550 Phosphopantetheine attachment site 12 75 2.3E-11 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS14260 0cbb76f73e20e21d599194a2cd50f485 79 SMART SM00823 Phosphopantetheine attachment site 8 67 4.1E-4 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS01855 0195bce1de1a1fc34d8dae062966e7fd 203 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 127 143 5.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS01855 0195bce1de1a1fc34d8dae062966e7fd 203 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 17 28 5.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS01855 0195bce1de1a1fc34d8dae062966e7fd 203 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 145 165 5.7E-5 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS01855 0195bce1de1a1fc34d8dae062966e7fd 203 Gene3D G3DSA:3.40.50.1000 1 202 2.2E-17 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS01855 0195bce1de1a1fc34d8dae062966e7fd 203 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 124 171 1.3E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS01855 0195bce1de1a1fc34d8dae062966e7fd 203 SUPERFAMILY SSF56784 3 190 6.0E-28 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS01855 0195bce1de1a1fc34d8dae062966e7fd 203 Pfam PF13419 Haloacid dehalogenase-like hydrolase 110 180 1.3E-7 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS13230 1e5e51570f77fe5cd75bb1929618ef82 204 Gene3D G3DSA:1.10.10.60 2 75 3.8E-17 T 28-03-2018 CNX65_RS13230 1e5e51570f77fe5cd75bb1929618ef82 204 Gene3D G3DSA:1.10.357.10 76 204 9.8E-21 T 28-03-2018 CNX65_RS13230 1e5e51570f77fe5cd75bb1929618ef82 204 Pfam PF00440 Bacterial regulatory proteins, tetR family 29 70 4.8E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13230 1e5e51570f77fe5cd75bb1929618ef82 204 SUPERFAMILY SSF46689 17 88 4.84E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 Gene3D G3DSA:3.40.50.2300 1 120 5.4E-38 T 28-03-2018 CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 SMART SM00448 3 113 7.7E-43 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 Gene3D G3DSA:1.10.10.10 121 222 9.0E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 Pfam PF00072 Response regulator receiver domain 5 114 5.8E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 SMART SM00862 150 221 6.7E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 151 221 9.0E-20 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 SUPERFAMILY SSF46894 127 221 2.66E-25 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS12980 c0e2c53fa00d094787dced48fc0ed423 222 SUPERFAMILY SSF52172 3 122 3.98E-41 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 38 55 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 PRINTS PR00069 Aldo-keto reductase signature 90 108 4.4E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 PRINTS PR00069 Aldo-keto reductase signature 157 186 4.4E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 PRINTS PR00069 Aldo-keto reductase signature 206 230 4.4E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 PRINTS PR00069 Aldo-keto reductase signature 34 58 4.4E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 PRINTS PR00069 Aldo-keto reductase signature 123 140 4.4E-46 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 Pfam PF00248 Aldo/keto reductase family 23 270 5.4E-42 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 123 140 - T 28-03-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 PIRSF PIRSF000097 1 279 3.1E-78 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 SUPERFAMILY SSF51430 3 276 5.76E-84 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS19740 597c99c93262c9de9da058641c05a8d6 295 Gene3D G3DSA:3.20.20.100 1 279 1.2E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS21245 3d14d2adf4ea19aff660f762c6584e12 301 SUPERFAMILY SSF161098 51 287 1.26E-42 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS21245 3d14d2adf4ea19aff660f762c6584e12 301 Gene3D G3DSA:1.10.3720.10 8 301 3.7E-39 T 28-03-2018 CNX65_RS21245 3d14d2adf4ea19aff660f762c6584e12 301 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 97 288 5.3E-7 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02100 2f2de4177d3c3f8c42af8353ef775e92 65 Pfam PF02597 ThiS family 5 65 2.8E-13 T 28-03-2018 IPR003749 ThiamineS/Molybdopterin converting factor subunit 1 Reactome: R-HSA-947581 CNX65_RS02100 2f2de4177d3c3f8c42af8353ef775e92 65 SUPERFAMILY SSF54285 3 65 2.36E-13 T 28-03-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp CNX65_RS02100 2f2de4177d3c3f8c42af8353ef775e92 65 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 5 65 4.4E-17 T 28-03-2018 IPR010035 ThiS, thiamine-biosynthesis CNX65_RS02100 2f2de4177d3c3f8c42af8353ef775e92 65 Gene3D G3DSA:3.10.20.30 3 65 5.1E-21 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS09120 399ee9a067a61d0dc6e122b4eeaff648 320 SUPERFAMILY SSF53474 2 320 3.33E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09120 399ee9a067a61d0dc6e122b4eeaff648 320 Gene3D G3DSA:3.40.50.1820 4 320 2.7E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09120 399ee9a067a61d0dc6e122b4eeaff648 320 Pfam PF05448 Acetyl xylan esterase (AXE1) 1 314 7.2E-87 T 28-03-2018 IPR008391 Acetyl xylan esterase CNX65_RS24395 cabbd444307750ec0d6993f8e53f546e 271 Pfam PF04240 Carotenoid biosynthesis protein 51 208 4.2E-34 T 28-03-2018 IPR007354 Carotene biosynthesis associated membrane protein CNX65_RS26775 e485e8f6f37b7131071419cfe13d3c5f 446 Gene3D G3DSA:2.60.40.10 110 209 1.7E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS26775 e485e8f6f37b7131071419cfe13d3c5f 446 Gene3D G3DSA:2.60.40.10 18 109 7.8E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS28465 f725e5dad16731c43f1c474a706dd382 206 SUPERFAMILY SSF109854 3 112 4.85E-6 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS28465 f725e5dad16731c43f1c474a706dd382 206 Gene3D G3DSA:1.20.120.450 1 176 5.1E-15 T 28-03-2018 CNX65_RS28465 f725e5dad16731c43f1c474a706dd382 206 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 4 182 5.0E-33 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS28465 f725e5dad16731c43f1c474a706dd382 206 TIGRFAM TIGR03085 TIGR03085: TIGR03085 family protein 4 199 3.2E-68 T 28-03-2018 IPR017519 Conserved hypothetical protein CHP03085 CNX65_RS02260 dd6bc8726531b2221d559f714f70a0a0 224 SUPERFAMILY SSF110395 1 211 4.84E-45 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CNX65_RS02260 dd6bc8726531b2221d559f714f70a0a0 224 Pfam PF03932 CutC family 2 194 2.3E-33 T 28-03-2018 IPR023648 Copper homeostasis CutC domain GO:0005507|GO:0055070 Reactome: R-HSA-936837 CNX65_RS02260 dd6bc8726531b2221d559f714f70a0a0 224 Gene3D G3DSA:3.20.20.380 1 224 4.0E-57 T 28-03-2018 CNX65_RS29100 1c0e0f0b16201f7e12d210a37fd551dc 152 SUPERFAMILY SSF50876 55 130 6.41E-15 T 28-03-2018 IPR005468 Avidin/streptavidin CNX65_RS29100 1c0e0f0b16201f7e12d210a37fd551dc 152 PRINTS PR00709 Avidin signature 112 128 3.0E-7 T 28-03-2018 IPR005469 Avidin CNX65_RS29100 1c0e0f0b16201f7e12d210a37fd551dc 152 PRINTS PR00709 Avidin signature 96 107 3.0E-7 T 28-03-2018 IPR005469 Avidin CNX65_RS29100 1c0e0f0b16201f7e12d210a37fd551dc 152 PRINTS PR00709 Avidin signature 39 47 3.0E-7 T 28-03-2018 IPR005469 Avidin CNX65_RS29100 1c0e0f0b16201f7e12d210a37fd551dc 152 Gene3D G3DSA:2.40.128.30 35 127 3.2E-15 T 28-03-2018 IPR005468 Avidin/streptavidin CNX65_RS29100 1c0e0f0b16201f7e12d210a37fd551dc 152 Pfam PF01382 Avidin family 39 123 1.4E-11 T 28-03-2018 IPR005468 Avidin/streptavidin CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF07676 WD40-like Beta Propeller Repeat 130 159 7.9E-6 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF07676 WD40-like Beta Propeller Repeat 362 388 4.7E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF07676 WD40-like Beta Propeller Repeat 42 66 0.0078 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF07676 WD40-like Beta Propeller Repeat 495 517 3.0E-5 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF07676 WD40-like Beta Propeller Repeat 172 194 0.0043 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF07676 WD40-like Beta Propeller Repeat 447 458 0.082 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF07676 WD40-like Beta Propeller Repeat 83 118 1.5E-7 T 28-03-2018 IPR011659 WD40-like Beta Propeller CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Gene3D G3DSA:2.30.40.10 598 658 1.5E-13 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 SUPERFAMILY SSF51556 644 945 3.4E-40 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Gene3D G3DSA:2.140.10.30 145 250 8.3E-20 T 28-03-2018 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 SUPERFAMILY SSF51338 573 645 1.07E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 SUPERFAMILY SSF51338 945 979 1.07E-12 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 SUPERFAMILY SSF69304 324 576 9.81E-35 T 28-03-2018 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Gene3D G3DSA:2.140.10.30 35 144 1.3E-18 T 28-03-2018 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Gene3D G3DSA:2.130.10.150 321 453 7.7E-23 T 28-03-2018 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Gene3D G3DSA:2.130.10.150 454 597 3.0E-13 T 28-03-2018 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Gene3D G3DSA:3.20.20.140 659 941 1.4E-28 T 28-03-2018 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 Pfam PF01979 Amidohydrolase family 641 979 1.3E-12 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS24895 09710f843a7687a8f320225e9cef9aee 1030 SUPERFAMILY SSF69304 40 242 1.57E-35 T 28-03-2018 CNX65_RS26190 d7562d1ba3d5c0c0c9cd9ac477c680f0 285 Gene3D G3DSA:3.40.50.720 118 280 8.1E-24 T 28-03-2018 CNX65_RS26190 d7562d1ba3d5c0c0c9cd9ac477c680f0 285 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 13 95 5.4E-20 T 28-03-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 CNX65_RS26190 d7562d1ba3d5c0c0c9cd9ac477c680f0 285 Gene3D G3DSA:3.40.50.10860 2 117 1.4E-33 T 28-03-2018 CNX65_RS26190 d7562d1ba3d5c0c0c9cd9ac477c680f0 285 TIGRFAM TIGR01809 Shik-DH-AROM: shikimate-5-dehydrogenase 7 273 5.1E-60 T 28-03-2018 IPR010110 Shikimate dehydrogenase, AroM-type GO:0004764|GO:0005737|GO:0055114 KEGG: 00400+4.2.1.10+1.1.1.25+2.7.1.71+2.5.1.19+4.2.3.4|MetaCyc: PWY-6163|MetaCyc: PWY-6164|MetaCyc: PWY-6416|MetaCyc: PWY-6707 CNX65_RS26190 d7562d1ba3d5c0c0c9cd9ac477c680f0 285 SUPERFAMILY SSF51735 108 276 2.08E-26 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS26190 d7562d1ba3d5c0c0c9cd9ac477c680f0 285 SUPERFAMILY SSF53223 8 107 1.73E-22 T 28-03-2018 CNX65_RS14105 7a823845ed1a1cc0d1a8a9877069eddc 187 Gene3D G3DSA:3.40.190.10 1 169 4.5E-4 T 28-03-2018 CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 Pfam PF06418 CTP synthase N-terminus 9 277 2.7E-121 T 28-03-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 Gene3D G3DSA:3.40.50.300 2 296 7.2E-127 T 28-03-2018 CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 Pfam PF00117 Glutamine amidotransferase class-I 312 543 1.4E-46 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 SUPERFAMILY SSF52317 299 547 1.14E-73 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 Gene3D G3DSA:3.40.50.880 297 550 9.5E-64 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 Hamap MF_01227 CTP synthase [pyrG]. 8 548 49.847 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 TIGRFAM TIGR00337 PyrG: CTP synthase 7 543 2.4E-226 T 28-03-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 CNX65_RS27060 6bec7047f22023df5e0fe4ddc35893c8 563 SUPERFAMILY SSF52540 8 277 1.79E-117 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13860 bf216d2f4cf4ed80b1fd41ab4a753d35 338 Pfam PF01497 Periplasmic binding protein 60 314 5.2E-23 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS13860 bf216d2f4cf4ed80b1fd41ab4a753d35 338 Gene3D G3DSA:3.40.50.1980 33 177 1.2E-25 T 28-03-2018 CNX65_RS13860 bf216d2f4cf4ed80b1fd41ab4a753d35 338 Gene3D G3DSA:3.40.50.1980 178 337 8.7E-37 T 28-03-2018 CNX65_RS13860 bf216d2f4cf4ed80b1fd41ab4a753d35 338 SUPERFAMILY SSF53807 57 335 2.98E-43 T 28-03-2018 CNX65_RS06265 f309e51236fd7381d9e6b891a40ad44d 142 Gene3D G3DSA:3.30.1460.10 7 141 2.7E-13 T 28-03-2018 CNX65_RS05140 64774d14d0da21f82d6772a3cc052d43 340 Pfam PF00296 Luciferase-like monooxygenase 23 304 6.5E-36 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS05140 64774d14d0da21f82d6772a3cc052d43 340 Gene3D G3DSA:3.20.20.30 12 329 7.4E-77 T 28-03-2018 CNX65_RS05140 64774d14d0da21f82d6772a3cc052d43 340 TIGRFAM TIGR03558 oxido_grp_1: luciferase family oxidoreductase, group 1 9 327 2.4E-131 T 28-03-2018 IPR019949 Luciferase family oxidoreductase, group 1 CNX65_RS05140 64774d14d0da21f82d6772a3cc052d43 340 SUPERFAMILY SSF51679 8 327 1.15E-78 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS04275 4a24ace0ffee6e92c727f9b1530440b9 446 SUPERFAMILY SSF53067 81 284 2.05E-48 T 28-03-2018 CNX65_RS04275 4a24ace0ffee6e92c727f9b1530440b9 446 SUPERFAMILY SSF53067 321 418 2.05E-48 T 28-03-2018 CNX65_RS04275 4a24ace0ffee6e92c727f9b1530440b9 446 Gene3D G3DSA:3.30.420.40 74 202 4.2E-30 T 28-03-2018 CNX65_RS04275 4a24ace0ffee6e92c727f9b1530440b9 446 Pfam PF00480 ROK family 84 416 3.2E-46 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS04275 4a24ace0ffee6e92c727f9b1530440b9 446 Gene3D G3DSA:1.10.10.10 8 73 5.2E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS04275 4a24ace0ffee6e92c727f9b1530440b9 446 Gene3D G3DSA:3.30.420.40 203 429 1.1E-44 T 28-03-2018 CNX65_RS04275 4a24ace0ffee6e92c727f9b1530440b9 446 SUPERFAMILY SSF46785 10 73 1.71E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12105 f0da652f7af1f4194f132dcbe9e2ca74 299 Gene3D G3DSA:3.40.50.720 1 297 1.8E-38 T 28-03-2018 CNX65_RS12105 f0da652f7af1f4194f132dcbe9e2ca74 299 SUPERFAMILY SSF51735 4 245 1.02E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12105 f0da652f7af1f4194f132dcbe9e2ca74 299 Pfam PF00106 short chain dehydrogenase 6 134 1.2E-9 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12105 f0da652f7af1f4194f132dcbe9e2ca74 299 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 4 155 0.0014 T 28-03-2018 CNX65_RS28570 a19a0762e0efab2a02420911aecb7b50 153 Pfam PF02834 LigT like Phosphoesterase 8 75 6.4E-7 T 28-03-2018 IPR014051 Phosphoesterase, HXTX CNX65_RS28570 a19a0762e0efab2a02420911aecb7b50 153 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 148 16.2 T 28-03-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 CNX65_RS28570 a19a0762e0efab2a02420911aecb7b50 153 Gene3D G3DSA:3.90.1140.10 1 153 6.3E-24 T 28-03-2018 CNX65_RS28570 a19a0762e0efab2a02420911aecb7b50 153 SUPERFAMILY SSF55144 2 148 2.44E-25 T 28-03-2018 IPR009097 Cyclic phosphodiesterase CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 1319 1392 3.0E-6 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 449 540 5.9E-21 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 886 965 3.3E-14 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 720 796 2.8E-8 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 541 623 1.6E-17 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 1048 1137 1.9E-14 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 966 1047 0.017 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 797 885 5.7E-9 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 624 716 1.1E-4 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 1138 1225 1.2E-4 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.500.10 1228 1308 3.7E-8 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.40.10 308 448 1.1E-5 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.40.10 1393 1495 0.027 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.40.1120 1781 1873 4.7E-5 T 28-03-2018 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Pfam PF01345 Domain of unknown function DUF11 313 409 5.0E-6 T 28-03-2018 IPR001434 Domain of unknown function DUF11 CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Pfam PF17210 SdrD B-like domain 1678 1759 2.4E-10 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 Gene3D G3DSA:2.60.40.10 1674 1778 1.8E-13 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS16995 b9314a8379a71fb6dd467f921fc9a6ef 1938 SUPERFAMILY SSF49478 1677 1759 3.88E-11 T 28-03-2018 CNX65_RS02905 dfe869445725af90e825ddb80d38a7c9 456 Pfam PF00144 Beta-lactamase 28 335 1.2E-60 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS02905 dfe869445725af90e825ddb80d38a7c9 456 Gene3D G3DSA:3.40.710.10 16 341 2.3E-71 T 28-03-2018 CNX65_RS02905 dfe869445725af90e825ddb80d38a7c9 456 SUPERFAMILY SSF56601 24 338 4.1E-69 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS20965 72f5310c97932377a195a605597f88c5 290 Pfam PF13560 Helix-turn-helix domain 7 85 1.1E-14 T 28-03-2018 CNX65_RS20965 72f5310c97932377a195a605597f88c5 290 SMART SM00530 10 82 1.5E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS20965 72f5310c97932377a195a605597f88c5 290 SUPERFAMILY SSF47413 29 81 2.85E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS20965 72f5310c97932377a195a605597f88c5 290 Gene3D G3DSA:1.10.260.40 4 93 6.9E-13 T 28-03-2018 CNX65_RS08555 3453ae72192e64f0d605519edff3f357 322 Gene3D G3DSA:1.10.260.40 23 137 4.7E-5 T 28-03-2018 CNX65_RS11860 76af98b247a422bdf4d8681f814d4889 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 78 97 3.8E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CNX65_RS11860 76af98b247a422bdf4d8681f814d4889 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 201 220 3.8E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CNX65_RS11860 76af98b247a422bdf4d8681f814d4889 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 19 40 3.8E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CNX65_RS11860 76af98b247a422bdf4d8681f814d4889 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 179 201 3.8E-22 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CNX65_RS11860 76af98b247a422bdf4d8681f814d4889 256 Pfam PF01311 Bacterial export proteins, family 1 11 244 1.9E-53 T 28-03-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 SMART SM00382 32 217 1.2E-12 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 Gene3D G3DSA:3.40.50.300 1 235 1.5E-48 T 28-03-2018 CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 Gene3D G3DSA:3.40.50.300 250 494 6.8E-33 T 28-03-2018 CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 SUPERFAMILY SSF52540 256 489 6.92E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 SUPERFAMILY SSF52540 7 226 1.1E-53 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 Pfam PF00005 ABC transporter 25 169 6.7E-28 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS31655 11e1dc0a0f3b1d165decc3e23a67adc7 514 Pfam PF00005 ABC transporter 274 430 1.2E-13 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS12560 30e4b8a12cb517fc071a8a0888c2f98a 396 SUPERFAMILY SSF53955 313 381 3.66E-8 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS12560 30e4b8a12cb517fc071a8a0888c2f98a 396 Pfam PF13560 Helix-turn-helix domain 9 72 4.7E-9 T 28-03-2018 CNX65_RS12560 30e4b8a12cb517fc071a8a0888c2f98a 396 Gene3D G3DSA:1.10.101.10 226 284 7.1E-12 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS12560 30e4b8a12cb517fc071a8a0888c2f98a 396 Gene3D G3DSA:1.10.530.10 285 396 3.7E-10 T 28-03-2018 CNX65_RS12560 30e4b8a12cb517fc071a8a0888c2f98a 396 SUPERFAMILY SSF47090 232 291 1.04E-11 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS12560 30e4b8a12cb517fc071a8a0888c2f98a 396 Pfam PF01471 Putative peptidoglycan binding domain 239 290 3.5E-7 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS12560 30e4b8a12cb517fc071a8a0888c2f98a 396 Gene3D G3DSA:1.10.260.40 2 77 0.0031 T 28-03-2018 CNX65_RS31600 d06fec3a47cc1d5242449f6a6ac66613 391 Pfam PF00877 NlpC/P60 family 292 377 3.9E-19 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CNX65_RS31600 d06fec3a47cc1d5242449f6a6ac66613 391 Gene3D G3DSA:3.90.1720.10 275 390 1.7E-28 T 28-03-2018 CNX65_RS31600 d06fec3a47cc1d5242449f6a6ac66613 391 SUPERFAMILY SSF54001 276 389 2.13E-29 T 28-03-2018 CNX65_RS31600 d06fec3a47cc1d5242449f6a6ac66613 391 SUPERFAMILY SSF140453 23 102 9.55E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS31600 d06fec3a47cc1d5242449f6a6ac66613 391 Gene3D G3DSA:1.10.287.1060 18 114 1.3E-7 T 28-03-2018 CNX65_RS27515 d3ffaa2dbbbfe6e52ce5eafb935940c9 211 Gene3D G3DSA:3.40.50.300 1 193 4.7E-7 T 28-03-2018 CNX65_RS27515 d3ffaa2dbbbfe6e52ce5eafb935940c9 211 SUPERFAMILY SSF52540 15 156 7.36E-9 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS11670 1ae2629d70f661ea680145971f0c97c6 283 PRINTS PR01217 Proline rich extensin signature 171 187 5.0E-11 T 28-03-2018 CNX65_RS11670 1ae2629d70f661ea680145971f0c97c6 283 PRINTS PR01217 Proline rich extensin signature 149 170 5.0E-11 T 28-03-2018 CNX65_RS11670 1ae2629d70f661ea680145971f0c97c6 283 PRINTS PR01217 Proline rich extensin signature 190 207 5.0E-11 T 28-03-2018 CNX65_RS11670 1ae2629d70f661ea680145971f0c97c6 283 PRINTS PR01217 Proline rich extensin signature 219 244 5.0E-11 T 28-03-2018 CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 Gene3D G3DSA:2.160.20.10 88 316 3.0E-67 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 SUPERFAMILY SSF51126 37 316 1.57E-79 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 SMART SM00710 240 273 5400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 SMART SM00710 138 160 530.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 SMART SM00710 217 239 5400.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 SMART SM00710 115 137 3.0 T 28-03-2018 IPR006626 Parallel beta-helix repeat CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 Pfam PF00544 Pectate lyase 69 250 4.8E-44 T 28-03-2018 IPR002022 Pectate lyase CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 Gene3D G3DSA:2.160.20.10 16 87 2.1E-12 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS09225 5799f8b7434631878e2daf2abff4716e 316 SMART SM00656 51 256 1.1E-55 T 28-03-2018 IPR002022 Pectate lyase CNX65_RS19865 a5aafac1783d785b378072bf3fc3264c 157 Pfam PF13560 Helix-turn-helix domain 64 132 2.2E-12 T 28-03-2018 CNX65_RS19865 a5aafac1783d785b378072bf3fc3264c 157 Gene3D G3DSA:1.10.260.40 55 129 2.7E-9 T 28-03-2018 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 Pfam PF04539 Sigma-70 region 3 104 174 3.7E-9 T 28-03-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 Pfam PF04542 Sigma-70 region 2 23 95 7.8E-10 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 Pfam PF04545 Sigma-70, region 4 188 236 3.1E-12 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 SUPERFAMILY SSF88659 97 157 3.01E-10 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 Gene3D G3DSA:1.10.1740.10 7 92 9.2E-13 T 28-03-2018 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 PRINTS PR00046 Major sigma-70 factor signature 192 204 3.2E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 PRINTS PR00046 Major sigma-70 factor signature 50 63 3.2E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 PRINTS PR00046 Major sigma-70 factor signature 209 224 3.2E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 PRINTS PR00046 Major sigma-70 factor signature 224 235 3.2E-5 T 28-03-2018 IPR000943 RNA polymerase sigma-70 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 Gene3D G3DSA:1.10.10.10 96 143 2.7E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 SUPERFAMILY SSF88946 19 95 2.98E-18 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 Gene3D G3DSA:1.10.10.10 160 242 1.4E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 237 1.2E-27 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 SUPERFAMILY SSF88659 161 242 4.11E-17 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS11990 10c8a221f2441ce03d96cf8ca1b45e77 294 PIRSF PIRSF000770 1 260 4.9E-56 T 28-03-2018 CNX65_RS07835 79f760aec15b6f2b3af9e38633dfb9dd 262 Pfam PF01872 RibD C-terminal domain 44 229 9.7E-30 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS07835 79f760aec15b6f2b3af9e38633dfb9dd 262 SUPERFAMILY SSF53597 42 260 7.98E-38 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS07835 79f760aec15b6f2b3af9e38633dfb9dd 262 Gene3D G3DSA:3.40.430.10 27 262 8.2E-49 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS24825 f86d2fb914410fc07cbc719ff375e3da 145 Gene3D G3DSA:3.40.50.2300 3 136 7.6E-31 T 28-03-2018 CNX65_RS24825 f86d2fb914410fc07cbc719ff375e3da 145 SUPERFAMILY SSF52172 9 134 1.12E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS24825 f86d2fb914410fc07cbc719ff375e3da 145 Pfam PF00072 Response regulator receiver domain 10 130 3.0E-20 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS24825 f86d2fb914410fc07cbc719ff375e3da 145 SMART SM00448 8 130 2.5E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 ProSitePatterns PS00683 Rhodanese C-terminal signature. 255 265 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 SUPERFAMILY SSF52821 149 275 9.82E-35 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 Gene3D G3DSA:3.40.250.10 154 281 8.7E-28 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 SUPERFAMILY SSF52821 5 140 1.83E-35 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 Gene3D G3DSA:3.40.250.10 1 141 1.8E-27 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 SMART SM00450 8 122 2.7E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 SMART SM00450 144 271 7.5E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 Pfam PF00581 Rhodanese-like domain 149 266 3.7E-17 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 Pfam PF00581 Rhodanese-like domain 9 118 3.8E-15 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS33765 bc98209c9a609bc5ba33f9ab0f20d01c 281 ProSitePatterns PS00380 Rhodanese signature 1. 34 45 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CNX65_RS28765 153e85c836c5cbb3a6ead290469fb412 228 Gene3D G3DSA:1.10.10.60 5 59 1.5E-16 T 28-03-2018 CNX65_RS28765 153e85c836c5cbb3a6ead290469fb412 228 Gene3D G3DSA:1.10.357.10 60 195 3.7E-21 T 28-03-2018 CNX65_RS28765 153e85c836c5cbb3a6ead290469fb412 228 SUPERFAMILY SSF48498 88 172 3.75E-12 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS28765 153e85c836c5cbb3a6ead290469fb412 228 Pfam PF13305 WHG domain 92 170 6.6E-14 T 28-03-2018 IPR025996 WHG domain CNX65_RS28765 153e85c836c5cbb3a6ead290469fb412 228 SUPERFAMILY SSF46689 6 79 4.74E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS28765 153e85c836c5cbb3a6ead290469fb412 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 8.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS32275 d8ce9b62cd6566898add50309c41b1b8 442 Pfam PF11203 Putative type VII ESX secretion system translocon, EccE 247 349 2.9E-24 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CNX65_RS32275 d8ce9b62cd6566898add50309c41b1b8 442 TIGRFAM TIGR03923 T7SS_EccE: type VII secretion protein EccE 68 440 1.7E-51 T 28-03-2018 IPR021368 Type VII secretion system protein EccE CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 Gene3D G3DSA:1.20.1560.10 6 323 1.7E-57 T 28-03-2018 CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 Pfam PF00664 ABC transporter transmembrane region 24 287 2.5E-36 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 Gene3D G3DSA:3.40.50.300 324 577 1.4E-70 T 28-03-2018 CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 SMART SM00382 363 549 5.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 Pfam PF00005 ABC transporter 354 503 2.9E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 ProSitePatterns PS00211 ABC transporters family signature. 475 489 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 SUPERFAMILY SSF52540 333 574 4.02E-77 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS12660 96029895a4efa89f4a74fa0f9cf62bd3 592 SUPERFAMILY SSF90123 10 324 7.72E-59 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS27030 f897d7f024678d062563383cb59eae3c 302 Gene3D G3DSA:3.40.50.300 41 302 1.0E-60 T 28-03-2018 CNX65_RS27030 f897d7f024678d062563383cb59eae3c 302 Pfam PF13614 AAA domain 52 228 1.6E-61 T 28-03-2018 IPR025669 AAA domain CNX65_RS27030 f897d7f024678d062563383cb59eae3c 302 SUPERFAMILY SSF52540 51 301 1.29E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS16360 b82ac4202ec17a5c0169410a2744bdb3 561 Pfam PF16116 Domain of unknown function (DUF4832) 340 541 7.4E-64 T 28-03-2018 IPR032267 Domain of unknown function DUF4832 CNX65_RS16360 b82ac4202ec17a5c0169410a2744bdb3 561 Pfam PF16173 Domain of unknown function (DUF4874) 163 328 1.4E-49 T 28-03-2018 IPR032379 Domain of unknown function DUF4874 CNX65_RS16360 b82ac4202ec17a5c0169410a2744bdb3 561 Gene3D G3DSA:3.20.20.150 144 310 6.4E-6 T 28-03-2018 CNX65_RS02440 6609387dbdfa91c2f7a3fb81dd85bf67 218 Gene3D G3DSA:1.10.150.240 28 71 1.4E-5 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CNX65_RS02440 6609387dbdfa91c2f7a3fb81dd85bf67 218 SUPERFAMILY SSF56784 5 199 5.42E-34 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS02440 6609387dbdfa91c2f7a3fb81dd85bf67 218 Gene3D G3DSA:3.40.50.1000 3 27 0.022 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS02440 6609387dbdfa91c2f7a3fb81dd85bf67 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 165 5.8E-10 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS02440 6609387dbdfa91c2f7a3fb81dd85bf67 218 Gene3D G3DSA:3.40.50.1000 72 206 3.9E-17 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34980 a021c5a41b465f1aaf19c1005a4417d9 521 PRINTS PR01806 Virulence factor MviN signature 354 373 2.3E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CNX65_RS34980 a021c5a41b465f1aaf19c1005a4417d9 521 PRINTS PR01806 Virulence factor MviN signature 256 282 2.3E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CNX65_RS34980 a021c5a41b465f1aaf19c1005a4417d9 521 PRINTS PR01806 Virulence factor MviN signature 24 43 2.3E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CNX65_RS34980 a021c5a41b465f1aaf19c1005a4417d9 521 PRINTS PR01806 Virulence factor MviN signature 121 145 2.3E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CNX65_RS34980 a021c5a41b465f1aaf19c1005a4417d9 521 PRINTS PR01806 Virulence factor MviN signature 43 59 2.3E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CNX65_RS34980 a021c5a41b465f1aaf19c1005a4417d9 521 PRINTS PR01806 Virulence factor MviN signature 145 166 2.3E-23 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CNX65_RS34980 a021c5a41b465f1aaf19c1005a4417d9 521 Pfam PF03023 MviN-like protein 21 460 2.2E-86 T 28-03-2018 IPR004268 Peptidoglycan biosynthesis protein MurJ CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 Gene3D G3DSA:3.90.1170.20 1 140 3.6E-43 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 115 285 5.3E-55 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 PIRSF PIRSF006250 6 287 2.4E-95 T 28-03-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 14 285 5.7E-91 T 28-03-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 Gene3D G3DSA:3.20.20.70 141 276 1.9E-39 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 SUPERFAMILY SSF54675 11 114 8.24E-29 T 28-03-2018 CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 26 113 5.6E-21 T 28-03-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 CNX65_RS28075 719a86a8dfbfd026ff671afd6e1c2746 287 SUPERFAMILY SSF51690 115 286 4.32E-55 T 28-03-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 CNX65_RS06560 5000c9b4a8d11b23905cae708ed8027a 393 Pfam PF13556 PucR C-terminal helix-turn-helix domain 325 382 9.5E-21 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS06560 5000c9b4a8d11b23905cae708ed8027a 393 Gene3D G3DSA:1.10.10.60 298 360 2.5E-5 T 28-03-2018 CNX65_RS14220 3cb2fbb89df4cd29a8eb042c17c36cde 318 SUPERFAMILY SSF55729 177 289 1.35E-6 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS14220 3cb2fbb89df4cd29a8eb042c17c36cde 318 Gene3D G3DSA:3.40.630.30 10 134 0.082 T 28-03-2018 CNX65_RS14220 3cb2fbb89df4cd29a8eb042c17c36cde 318 Gene3D G3DSA:3.40.630.30 167 298 1.5E-8 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 SUPERFAMILY SSF51905 7 363 2.87E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 10 328 2.3E-54 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 143 161 1.4E-9 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.4E-9 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.4E-9 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 Gene3D G3DSA:3.50.50.60 197 391 1.8E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 Gene3D G3DSA:3.50.50.60 4 196 1.1E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 155 6.9E-8 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 6.9E-8 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 280 294 6.9E-8 T 28-03-2018 CNX65_RS20190 f13423ecca125fc264c61c9cf95d8a2c 527 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 8 30 6.9E-8 T 28-03-2018 CNX65_RS05430 ba4b453e9ec2959268db391addc458d4 542 Pfam PF00171 Aldehyde dehydrogenase family 56 520 3.2E-99 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS05430 ba4b453e9ec2959268db391addc458d4 542 SUPERFAMILY SSF53720 8 526 2.09E-124 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS05430 ba4b453e9ec2959268db391addc458d4 542 Gene3D G3DSA:3.40.309.10 312 504 1.3E-48 T 28-03-2018 CNX65_RS05430 ba4b453e9ec2959268db391addc458d4 542 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 320 331 - T 28-03-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS05430 ba4b453e9ec2959268db391addc458d4 542 TIGRFAM TIGR01236 D1pyr5carbox1: 1-pyrroline-5-carboxylate dehydrogenase 12 540 6.6E-245 T 28-03-2018 IPR005931 Delta-1-pyrroline-5-carboxylate dehydrogenase GO:0003842|GO:0010133 KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853|Reactome: R-HSA-389661|Reactome: R-HSA-70688 CNX65_RS05430 ba4b453e9ec2959268db391addc458d4 542 Gene3D G3DSA:3.40.605.10 36 311 4.4E-66 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS22335 7f036cfa66804ab273c3c69ae44e759a 385 Pfam PF01494 FAD binding domain 3 292 1.1E-20 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS22335 7f036cfa66804ab273c3c69ae44e759a 385 Gene3D G3DSA:3.50.50.60 1 341 1.0E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22335 7f036cfa66804ab273c3c69ae44e759a 385 SUPERFAMILY SSF51905 2 167 3.71E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22335 7f036cfa66804ab273c3c69ae44e759a 385 SUPERFAMILY SSF51905 258 346 3.71E-41 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS22335 7f036cfa66804ab273c3c69ae44e759a 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 146 161 2.7E-7 T 28-03-2018 CNX65_RS22335 7f036cfa66804ab273c3c69ae44e759a 385 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.7E-7 T 28-03-2018 CNX65_RS01210 11cdc6bc3869cd41569d6ecad4d5a30c 218 SUPERFAMILY SSF52833 98 199 3.02E-18 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS01210 11cdc6bc3869cd41569d6ecad4d5a30c 218 Pfam PF00578 AhpC/TSA family 97 199 3.1E-9 T 28-03-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 CNX65_RS01210 11cdc6bc3869cd41569d6ecad4d5a30c 218 Gene3D G3DSA:3.40.30.10 49 218 3.2E-15 T 28-03-2018 CNX65_RS01210 11cdc6bc3869cd41569d6ecad4d5a30c 218 ProSitePatterns PS00194 Thioredoxin family active site. 113 131 - T 28-03-2018 IPR017937 Thioredoxin, conserved site GO:0045454 CNX65_RS01795 46fa6981bec08d54e3a1d0c46eca36de 297 Gene3D G3DSA:1.10.3720.10 15 284 2.3E-45 T 28-03-2018 CNX65_RS01795 46fa6981bec08d54e3a1d0c46eca36de 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 287 5.9E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS01795 46fa6981bec08d54e3a1d0c46eca36de 297 SUPERFAMILY SSF161098 21 297 6.41E-68 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS06715 0093453510fef76052db9587e59164d4 345 SUPERFAMILY SSF52733 6 341 2.62E-111 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06715 0093453510fef76052db9587e59164d4 345 Gene3D G3DSA:1.10.1610.10 4 69 1.8E-30 T 28-03-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06715 0093453510fef76052db9587e59164d4 345 Gene3D G3DSA:3.40.50.10210 70 324 7.8E-104 T 28-03-2018 CNX65_RS06715 0093453510fef76052db9587e59164d4 345 Pfam PF02277 Phosphoribosyltransferase 9 341 7.5E-135 T 28-03-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06715 0093453510fef76052db9587e59164d4 345 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 10 343 36.318 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS06715 0093453510fef76052db9587e59164d4 345 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 13 341 2.0E-126 T 28-03-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5508|MetaCyc: PWY-5509|MetaCyc: PWY-6269 CNX65_RS24960 af769e6dab188b54e15404426b9593b4 352 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 170 331 2.3E-17 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24960 af769e6dab188b54e15404426b9593b4 352 SMART SM00644 159 331 0.0087 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24960 af769e6dab188b54e15404426b9593b4 352 SUPERFAMILY SSF55846 142 342 2.04E-35 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24960 af769e6dab188b54e15404426b9593b4 352 Gene3D G3DSA:3.40.80.10 130 350 7.9E-39 T 28-03-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS24960 af769e6dab188b54e15404426b9593b4 352 SMART SM00701 140 313 6.0E-8 T 28-03-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 CNX65_RS22435 c2368c9199980ae3bb9f88a08836664d 693 Pfam PF13538 UvrD-like helicase C-terminal domain 645 687 4.7E-7 T 28-03-2018 IPR027785 UvrD-like helicase C-terminal domain CNX65_RS22435 c2368c9199980ae3bb9f88a08836664d 693 Pfam PF13245 AAA domain 177 528 1.7E-13 T 28-03-2018 CNX65_RS22435 c2368c9199980ae3bb9f88a08836664d 693 Gene3D G3DSA:3.40.50.300 171 545 6.0E-34 T 28-03-2018 CNX65_RS22435 c2368c9199980ae3bb9f88a08836664d 693 SUPERFAMILY SSF52540 166 243 4.41E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22435 c2368c9199980ae3bb9f88a08836664d 693 SUPERFAMILY SSF52540 481 687 4.41E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22435 c2368c9199980ae3bb9f88a08836664d 693 Gene3D G3DSA:3.40.50.300 554 688 8.6E-10 T 28-03-2018 CNX65_RS14500 94fb842bbbdf5566b27d22bd88507784 378 Pfam PF01494 FAD binding domain 4 324 3.3E-14 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS14500 94fb842bbbdf5566b27d22bd88507784 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 1.4E-15 T 28-03-2018 CNX65_RS14500 94fb842bbbdf5566b27d22bd88507784 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 147 162 1.4E-15 T 28-03-2018 CNX65_RS14500 94fb842bbbdf5566b27d22bd88507784 378 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 287 302 1.4E-15 T 28-03-2018 CNX65_RS14500 94fb842bbbdf5566b27d22bd88507784 378 Gene3D G3DSA:3.50.50.60 1 366 9.2E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS14500 94fb842bbbdf5566b27d22bd88507784 378 SUPERFAMILY SSF51905 272 364 1.53E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS14500 94fb842bbbdf5566b27d22bd88507784 378 SUPERFAMILY SSF51905 4 168 1.53E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS17745 b9c2fda7501c06e1cba6502e8fd4b06d 200 Gene3D G3DSA:3.40.50.620 38 167 1.5E-13 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS17745 b9c2fda7501c06e1cba6502e8fd4b06d 200 Pfam PF02698 DUF218 domain 45 156 8.5E-16 T 28-03-2018 IPR003848 Domain of unknown function DUF218 CNX65_RS34860 d75d02c58a4140dd1f43017438d6f23b 381 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 288 373 1.7E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34860 d75d02c58a4140dd1f43017438d6f23b 381 SUPERFAMILY SSF55874 270 379 2.23E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34860 d75d02c58a4140dd1f43017438d6f23b 381 Gene3D G3DSA:3.30.565.10 177 379 3.2E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS14070 07feb6ccfb1b14c73f009b287baf1c7b 337 SUPERFAMILY SSF51556 37 300 1.48E-38 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS14070 07feb6ccfb1b14c73f009b287baf1c7b 337 Gene3D G3DSA:3.20.20.140 53 300 4.9E-29 T 28-03-2018 CNX65_RS14070 07feb6ccfb1b14c73f009b287baf1c7b 337 Gene3D G3DSA:2.30.40.10 5 52 1.8E-4 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS14070 07feb6ccfb1b14c73f009b287baf1c7b 337 Pfam PF01979 Amidohydrolase family 142 329 2.1E-6 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS13295 c888af5f979c8311842df654745ef7ea 222 Gene3D G3DSA:2.30.110.10 56 212 1.8E-33 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS13295 c888af5f979c8311842df654745ef7ea 222 Pfam PF01613 Flavin reductase like domain 66 211 3.3E-24 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS13295 c888af5f979c8311842df654745ef7ea 222 SUPERFAMILY SSF50475 57 210 4.91E-34 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS13295 c888af5f979c8311842df654745ef7ea 222 SMART SM00903 64 210 1.4E-35 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 Pfam PF00067 Cytochrome P450 199 364 7.2E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 272 283 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 289 316 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 317 332 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 130 146 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 147 162 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 191 213 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 347 358 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 83 94 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 PRINTS PR00359 B-class P450 signature 338 347 3.9E-50 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 Gene3D G3DSA:1.10.630.10 2 396 2.4E-65 T 28-03-2018 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 340 349 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS18100 b90fcf6119f6640e80d30a97642b0c18 396 SUPERFAMILY SSF48264 4 396 1.31E-81 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 17 219 3.8E-43 T 28-03-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 7 105 2.4E-26 T 28-03-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 SUPERFAMILY SSF46548 123 220 3.66E-17 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 Gene3D G3DSA:3.10.20.30 2 102 7.5E-27 T 28-03-2018 IPR012675 Beta-grasp domain CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 Pfam PF13183 4Fe-4S dicluster domain 140 216 3.8E-14 T 28-03-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 SUPERFAMILY SSF54292 6 103 7.47E-23 T 28-03-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 53 61 - T 28-03-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 CNX65_RS07070 84238bcb06e750881391eb5e51295986 249 Gene3D G3DSA:1.10.1060.10 103 236 3.0E-11 T 28-03-2018 CNX65_RS21355 0160be15cb7c6725c2783c8b4913ef3e 694 Pfam PF00144 Beta-lactamase 70 394 1.5E-60 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS21355 0160be15cb7c6725c2783c8b4913ef3e 694 SUPERFAMILY SSF56601 67 380 1.19E-65 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS21355 0160be15cb7c6725c2783c8b4913ef3e 694 Gene3D G3DSA:3.40.710.10 56 410 7.6E-72 T 28-03-2018 CNX65_RS05060 a20291d8df160fbf241ac63b57dc692e 151 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 120 6.8E-26 T 28-03-2018 IPR028090 JAB domain, prokaryotic CNX65_RS05060 a20291d8df160fbf241ac63b57dc692e 151 SMART SM00232 1 136 1.7E-25 T 28-03-2018 IPR000555 JAB1/MPN/MOV34 metalloenzyme domain GO:0005515 CNX65_RS05060 a20291d8df160fbf241ac63b57dc692e 151 SUPERFAMILY SSF102712 2 130 1.11E-28 T 28-03-2018 CNX65_RS05060 a20291d8df160fbf241ac63b57dc692e 151 Gene3D G3DSA:3.40.140.10 1 137 6.7E-28 T 28-03-2018 CNX65_RS22855 2955057c9352b327ee361b9d5a6e494f 184 SUPERFAMILY SSF52540 5 103 1.14E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22855 2955057c9352b327ee361b9d5a6e494f 184 Gene3D G3DSA:3.40.50.300 2 172 8.1E-14 T 28-03-2018 CNX65_RS00060 c41dda9e041bb4517b9f1dd8010fc9f8 181 Gene3D G3DSA:3.40.1000.10 39 180 9.4E-51 T 28-03-2018 CNX65_RS00060 c41dda9e041bb4517b9f1dd8010fc9f8 181 Pfam PF09449 Domain of unknown function (DUF2020) 50 179 1.2E-36 T 28-03-2018 IPR018567 Domain of unknown function DUF2020 CNX65_RS00060 c41dda9e041bb4517b9f1dd8010fc9f8 181 SUPERFAMILY SSF55724 38 179 9.42E-50 T 28-03-2018 IPR016123 Mog1/PsbP, alpha/beta/alpha sandwich Reactome: R-HSA-5576892 CNX65_RS04820 91a154b9f7b0652631b8f881d06245a3 157 Pfam PF13091 PLD-like domain 56 155 5.1E-10 T 28-03-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 CNX65_RS04820 91a154b9f7b0652631b8f881d06245a3 157 Gene3D G3DSA:3.30.870.10 21 157 6.1E-9 T 28-03-2018 CNX65_RS04820 91a154b9f7b0652631b8f881d06245a3 157 SUPERFAMILY SSF56024 55 155 7.06E-8 T 28-03-2018 CNX65_RS31385 0e4bf191ad048c504f4a9e1860e8025f 73 Pfam PF13822 Acyl-CoA carboxylase epsilon subunit 6 66 2.9E-22 T 28-03-2018 IPR032716 Acyl-CoA carboxylase epsilon subunit CNX65_RS04160 d4011bd42f1d391fc3b197ca25dae31a 225 Pfam PF00072 Response regulator receiver domain 7 115 5.3E-22 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS04160 d4011bd42f1d391fc3b197ca25dae31a 225 SUPERFAMILY SSF52172 5 178 4.98E-33 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS04160 d4011bd42f1d391fc3b197ca25dae31a 225 SMART SM00862 147 220 1.7E-25 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS04160 d4011bd42f1d391fc3b197ca25dae31a 225 Gene3D G3DSA:3.40.50.2300 2 122 1.7E-27 T 28-03-2018 CNX65_RS04160 d4011bd42f1d391fc3b197ca25dae31a 225 Pfam PF00486 Transcriptional regulatory protein, C terminal 149 220 2.3E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS04160 d4011bd42f1d391fc3b197ca25dae31a 225 SMART SM00448 5 115 4.2E-33 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS04160 d4011bd42f1d391fc3b197ca25dae31a 225 Gene3D G3DSA:1.10.10.10 123 225 2.7E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31150 a54ec1b4b748c41a3a59c3078fba294b 102 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 19 102 19.205 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS31150 a54ec1b4b748c41a3a59c3078fba294b 102 Pfam PF02467 Transcription factor WhiB 34 97 4.8E-27 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS06935 134189b8015ab4d8e861a52beb030ae0 296 Gene3D G3DSA:3.20.20.220 1 296 2.1E-94 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CNX65_RS06935 134189b8015ab4d8e861a52beb030ae0 296 SUPERFAMILY SSF51730 4 290 4.71E-88 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CNX65_RS06935 134189b8015ab4d8e861a52beb030ae0 296 Pfam PF02219 Methylenetetrahydrofolate reductase 7 288 7.1E-90 T 28-03-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 CNX65_RS07600 3434eac1d0e3961736539b5598d29c19 416 SUPERFAMILY SSF140459 33 179 8.11E-11 T 28-03-2018 CNX65_RS07600 3434eac1d0e3961736539b5598d29c19 416 Pfam PF00823 PPE family 33 164 8.6E-9 T 28-03-2018 IPR000030 PPE family CNX65_RS07600 3434eac1d0e3961736539b5598d29c19 416 Gene3D G3DSA:1.10.287.850 26 106 4.9E-4 T 28-03-2018 CNX65_RS09625 f1c2241de3dc4967e542260291c6fc21 439 Gene3D G3DSA:3.40.190.10 38 162 2.4E-18 T 28-03-2018 CNX65_RS09625 f1c2241de3dc4967e542260291c6fc21 439 Gene3D G3DSA:3.40.190.10 163 434 1.9E-33 T 28-03-2018 CNX65_RS09625 f1c2241de3dc4967e542260291c6fc21 439 Pfam PF01547 Bacterial extracellular solute-binding protein 49 332 1.3E-25 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS09625 f1c2241de3dc4967e542260291c6fc21 439 SUPERFAMILY SSF53850 23 424 1.04E-58 T 28-03-2018 CNX65_RS29220 c2ad67e9aac8318d3be559cf7417332d 261 Gene3D G3DSA:3.40.1130.10 5 206 3.1E-43 T 28-03-2018 CNX65_RS29220 c2ad67e9aac8318d3be559cf7417332d 261 Pfam PF01553 Acyltransferase 23 149 3.4E-26 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS29220 c2ad67e9aac8318d3be559cf7417332d 261 SMART SM00563 38 152 6.1E-32 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS29220 c2ad67e9aac8318d3be559cf7417332d 261 SUPERFAMILY SSF69593 20 196 1.24E-36 T 28-03-2018 CNX65_RS13045 e6a6934d2bf20483b71875051eee7d09 266 Gene3D G3DSA:2.160.20.10 53 265 1.5E-85 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS13045 e6a6934d2bf20483b71875051eee7d09 266 Pfam PF03211 Pectate lyase 39 241 1.4E-85 T 28-03-2018 IPR004898 Pectate lyase PlyH/PlyE-like GO:0005576|GO:0030570 KEGG: 00040+4.2.2.2 CNX65_RS13045 e6a6934d2bf20483b71875051eee7d09 266 SUPERFAMILY SSF51126 48 226 6.28E-58 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS03890 8a05da01562ed21590dd79beed814f85 55 Pfam PF11314 Protein of unknown function (DUF3117) 4 52 1.8E-29 T 28-03-2018 IPR021465 Protein of unknown function DUF3117 CNX65_RS10485 d0b94c36e36af528099d8ba9e4fb4c28 370 Pfam PF00005 ABC transporter 23 168 1.2E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS10485 d0b94c36e36af528099d8ba9e4fb4c28 370 SUPERFAMILY SSF54631 254 360 3.13E-5 T 28-03-2018 CNX65_RS10485 d0b94c36e36af528099d8ba9e4fb4c28 370 Gene3D G3DSA:3.40.50.300 2 288 5.9E-74 T 28-03-2018 CNX65_RS10485 d0b94c36e36af528099d8ba9e4fb4c28 370 SMART SM00382 31 227 1.8E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS10485 d0b94c36e36af528099d8ba9e4fb4c28 370 Gene3D G3DSA:3.10.580.10 308 368 0.05 T 28-03-2018 CNX65_RS10485 d0b94c36e36af528099d8ba9e4fb4c28 370 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS10485 d0b94c36e36af528099d8ba9e4fb4c28 370 SUPERFAMILY SSF52540 5 244 1.56E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS20730 2cef5628ba01b163b08e80fd6d55ae8c 469 Gene3D G3DSA:3.40.710.10 83 445 3.5E-15 T 28-03-2018 CNX65_RS20730 2cef5628ba01b163b08e80fd6d55ae8c 469 SUPERFAMILY SSF56601 177 300 1.63E-14 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS20730 2cef5628ba01b163b08e80fd6d55ae8c 469 SUPERFAMILY SSF56601 350 434 1.63E-14 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS20730 2cef5628ba01b163b08e80fd6d55ae8c 469 Pfam PF13354 Beta-lactamase enzyme family 179 417 1.8E-7 T 28-03-2018 CNX65_RS23690 36bc35e2bc35ee84b9e5532eb2dce21e 287 TIGRFAM TIGR03770 anch_rpt_perm: anchored repeat-type ABC transporter, permease subunit 13 269 6.1E-114 T 28-03-2018 IPR022392 Anchored repeat-type ABC transporter, permease subunit CNX65_RS23690 36bc35e2bc35ee84b9e5532eb2dce21e 287 SUPERFAMILY SSF81345 7 264 1.09E-40 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS23690 36bc35e2bc35ee84b9e5532eb2dce21e 287 Gene3D G3DSA:1.10.3470.10 10 276 4.7E-27 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS23690 36bc35e2bc35ee84b9e5532eb2dce21e 287 Pfam PF00950 ABC 3 transport family 13 268 6.1E-70 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CNX65_RS30600 4744b5e52fe46c31d1a95c1f3d959edc 260 SUPERFAMILY SSF51735 21 212 1.41E-31 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS30600 4744b5e52fe46c31d1a95c1f3d959edc 260 Gene3D G3DSA:3.40.50.720 15 204 1.2E-23 T 28-03-2018 CNX65_RS30600 4744b5e52fe46c31d1a95c1f3d959edc 260 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 21 109 1.2E-15 T 28-03-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal CNX65_RS34035 833814e40f035ace830b44db21a0560f 254 Gene3D G3DSA:3.40.50.300 6 251 4.8E-76 T 28-03-2018 CNX65_RS34035 833814e40f035ace830b44db21a0560f 254 SMART SM00382 35 222 7.8E-19 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS34035 833814e40f035ace830b44db21a0560f 254 SUPERFAMILY SSF52540 11 244 4.84E-75 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34035 833814e40f035ace830b44db21a0560f 254 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS34035 833814e40f035ace830b44db21a0560f 254 Pfam PF00005 ABC transporter 26 174 2.2E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS34035 833814e40f035ace830b44db21a0560f 254 PIRSF PIRSF039085 7 250 1.5E-98 T 28-03-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 CNX65_RS32385 3837e997a7da4284c7e0da309b479e5b 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 25.534 T 28-03-2018 IPR023053 Ribosomal protein S14, type Z CNX65_RS32385 3837e997a7da4284c7e0da309b479e5b 61 Gene3D G3DSA:4.10.830.10 1 61 2.5E-22 T 28-03-2018 CNX65_RS32385 3837e997a7da4284c7e0da309b479e5b 61 SUPERFAMILY SSF57716 4 61 2.07E-21 T 28-03-2018 CNX65_RS32385 3837e997a7da4284c7e0da309b479e5b 61 Pfam PF00253 Ribosomal protein S14p/S29e 11 60 3.1E-24 T 28-03-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32385 3837e997a7da4284c7e0da309b479e5b 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 28-03-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS22075 792885011ff93ccad8cfdd440dbb9361 393 Gene3D G3DSA:3.40.50.2000 4 200 4.6E-25 T 28-03-2018 CNX65_RS22075 792885011ff93ccad8cfdd440dbb9361 393 Pfam PF00534 Glycosyl transferases group 1 205 360 1.4E-32 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS22075 792885011ff93ccad8cfdd440dbb9361 393 Pfam PF13439 Glycosyltransferase Family 4 21 190 3.4E-31 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS22075 792885011ff93ccad8cfdd440dbb9361 393 Gene3D G3DSA:3.40.50.2000 201 368 3.4E-43 T 28-03-2018 CNX65_RS22075 792885011ff93ccad8cfdd440dbb9361 393 SUPERFAMILY SSF53756 22 382 1.16E-83 T 28-03-2018 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 PIRSF PIRSF002599 1 68 2.1E-26 T 28-03-2018 IPR012156 Cold shock, CspA GO:0003676 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 PRINTS PR00050 Cold shock protein signature 26 35 7.6E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 PRINTS PR00050 Cold shock protein signature 41 59 7.6E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 PRINTS PR00050 Cold shock protein signature 5 20 7.6E-18 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 Pfam PF00313 'Cold-shock' DNA-binding domain 3 67 5.3E-32 T 28-03-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 SUPERFAMILY SSF50249 2 67 4.04E-26 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 SMART SM00357 4 68 3.4E-30 T 28-03-2018 IPR011129 Cold shock domain GO:0003676 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 Gene3D G3DSA:2.40.50.140 1 68 2.4E-29 T 28-03-2018 CNX65_RS05230 02939dcc89b8053098601058025ec6b2 68 ProSitePatterns PS00352 'Cold-shock' domain signature. 16 35 - T 28-03-2018 IPR019844 Cold-shock conserved site CNX65_RS20385 5d59b0614a35a5564f002549872d3972 418 Pfam PF12704 MacB-like periplasmic core domain 48 262 4.4E-10 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CNX65_RS20385 5d59b0614a35a5564f002549872d3972 418 Pfam PF02687 FtsX-like permease family 323 411 5.2E-13 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS27435 fbc82c4337ce30904d1f7d502db1bb73 195 Pfam PF00583 Acetyltransferase (GNAT) family 56 149 2.3E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS27435 fbc82c4337ce30904d1f7d502db1bb73 195 SUPERFAMILY SSF55729 4 175 3.21E-25 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS27435 fbc82c4337ce30904d1f7d502db1bb73 195 Gene3D G3DSA:3.40.630.30 4 178 1.7E-26 T 28-03-2018 CNX65_RS08615 0e1547a5b8219ebc843b0f558d403988 207 SUPERFAMILY SSF81296 26 121 1.33E-18 T 28-03-2018 IPR014756 Immunoglobulin E-set CNX65_RS08615 0e1547a5b8219ebc843b0f558d403988 207 Pfam PF04234 CopC domain 27 120 8.6E-20 T 28-03-2018 IPR007348 CopC domain GO:0005507|GO:0042597|GO:0046688 CNX65_RS08615 0e1547a5b8219ebc843b0f558d403988 207 Gene3D G3DSA:2.60.40.1220 26 122 3.0E-23 T 28-03-2018 CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 SUPERFAMILY SSF55874 115 215 1.19E-15 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 123 216 3.9E-6 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 SMART SM00387 121 218 3.1E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 Pfam PF07730 Histidine kinase 16 80 1.9E-12 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 Gene3D G3DSA:3.30.565.10 12 217 3.3E-20 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 PRINTS PR00344 Bacterial sensor protein C-terminal signature 178 196 1.3E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 PRINTS PR00344 Bacterial sensor protein C-terminal signature 156 170 1.3E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS26760 2466366dde4f08f1fd0650e37e921317 218 PRINTS PR00344 Bacterial sensor protein C-terminal signature 202 215 1.3E-5 T 28-03-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 CNX65_RS05070 3cf30dac48e13fd1bc60237cbe500a09 316 SUPERFAMILY SSF53686 4 296 6.68E-82 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS05070 3cf30dac48e13fd1bc60237cbe500a09 316 TIGRFAM TIGR01136 cysKM: cysteine synthase 9 299 2.1E-104 T 28-03-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 CNX65_RS05070 3cf30dac48e13fd1bc60237cbe500a09 316 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 28-03-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 CNX65_RS05070 3cf30dac48e13fd1bc60237cbe500a09 316 Gene3D G3DSA:3.40.50.1100 24 135 2.0E-35 T 28-03-2018 CNX65_RS05070 3cf30dac48e13fd1bc60237cbe500a09 316 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 286 7.5E-63 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS05070 3cf30dac48e13fd1bc60237cbe500a09 316 Gene3D G3DSA:3.40.50.1100 136 309 1.9E-36 T 28-03-2018 CNX65_RS12000 55757b3ad5b5371e66154b972a35e13b 459 Pfam PF00460 Flagella basal body rod protein 10 37 5.3E-5 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CNX65_RS12000 55757b3ad5b5371e66154b972a35e13b 459 SUPERFAMILY SSF64518 172 455 1.83E-18 T 28-03-2018 CNX65_RS12000 55757b3ad5b5371e66154b972a35e13b 459 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 387 455 2.3E-14 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CNX65_RS12000 55757b3ad5b5371e66154b972a35e13b 459 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 455 1.9E-91 T 28-03-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 CNX65_RS12000 55757b3ad5b5371e66154b972a35e13b 459 Gene3D G3DSA:1.20.120.20 97 458 9.3E-4 T 28-03-2018 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 Gene3D G3DSA:1.10.260.40 13 76 1.2E-5 T 28-03-2018 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 Pfam PF00400 WD domain, G-beta repeat 694 730 0.0057 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 Pfam PF00400 WD domain, G-beta repeat 785 819 4.2E-4 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SUPERFAMILY SSF52540 112 299 3.35E-8 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 ProSitePatterns PS00678 Trp-Asp (WD) repeats signature. 806 820 - T 28-03-2018 IPR019775 WD40 repeat, conserved site CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SUPERFAMILY SSF50978 607 876 1.26E-39 T 28-03-2018 IPR017986 WD40-repeat-containing domain GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SMART SM00320 736 774 0.34 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SMART SM00320 780 819 1.1E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SMART SM00320 649 685 54.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SMART SM00320 691 730 1.5E-6 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SMART SM00320 604 643 150.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 SMART SM00320 825 864 13.0 T 28-03-2018 IPR001680 WD40 repeat GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 Gene3D G3DSA:2.130.10.10 601 887 2.8E-44 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS08940 a8dd071354c147eadda3401ee4465bd8 901 Gene3D G3DSA:3.40.50.300 104 506 3.8E-9 T 28-03-2018 CNX65_RS28925 06b97965438b7a8c74b1577aa0baf1b8 275 Gene3D G3DSA:1.10.3720.10 5 265 9.9E-36 T 28-03-2018 CNX65_RS28925 06b97965438b7a8c74b1577aa0baf1b8 275 SUPERFAMILY SSF161098 3 253 4.97E-48 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS28925 06b97965438b7a8c74b1577aa0baf1b8 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 76 247 1.7E-12 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS06635 973b1b41f65f30af846de59b642f71bf 311 SUPERFAMILY SSF51679 9 310 7.2E-69 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS06635 973b1b41f65f30af846de59b642f71bf 311 Pfam PF00296 Luciferase-like monooxygenase 9 250 7.7E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS06635 973b1b41f65f30af846de59b642f71bf 311 TIGRFAM TIGR03560 F420_Rv1855c: probable F420-dependent oxidoreductase, Rv1855c family 2 230 3.9E-91 T 28-03-2018 IPR019952 F420-dependent oxidoreductase-predicted, Rv1855c CNX65_RS06635 973b1b41f65f30af846de59b642f71bf 311 Gene3D G3DSA:3.20.20.30 2 311 1.7E-70 T 28-03-2018 CNX65_RS17220 ff347d6186a769f4377a87eb6daa941d 130 Gene3D G3DSA:3.10.129.10 3 130 1.2E-13 T 28-03-2018 CNX65_RS17220 ff347d6186a769f4377a87eb6daa941d 130 SUPERFAMILY SSF54637 13 126 2.33E-10 T 28-03-2018 IPR029069 HotDog domain CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 Gene3D G3DSA:2.60.40.1180 379 476 9.2E-19 T 28-03-2018 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 SMART SM00060 482 557 1.2E-6 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 SUPERFAMILY SSF51445 59 352 2.19E-42 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 SUPERFAMILY SSF49265 478 570 1.24E-9 T 28-03-2018 IPR003961 Fibronectin type III GO:0005515 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 Gene3D G3DSA:3.20.20.80 53 378 2.7E-56 T 28-03-2018 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 SUPERFAMILY SSF49384 570 677 7.67E-25 T 28-03-2018 IPR008965 Carbohydrate-binding domain GO:0030246 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 Gene3D G3DSA:2.60.40.290 572 676 2.6E-28 T 28-03-2018 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 SMART SM00637 575 676 7.1E-29 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 Pfam PF00553 Cellulose binding domain 575 676 1.0E-21 T 28-03-2018 IPR001919 Carbohydrate-binding type-2 domain GO:0004553|GO:0005975|GO:0030246 CNX65_RS10470 6ecc2fd9320c5695a7f24ec949d44884 679 Gene3D G3DSA:2.60.40.10 477 571 1.2E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS27390 f27a36d2b1ded6cf89fca15f16faf00b 256 Pfam PF07264 Etoposide-induced protein 2.4 (EI24) 13 231 1.2E-31 T 28-03-2018 CNX65_RS28125 d34066525773e637d6864a06c1e0dbd6 242 Pfam PF13500 AAA domain 8 204 5.7E-34 T 28-03-2018 CNX65_RS28125 d34066525773e637d6864a06c1e0dbd6 242 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 10 173 1.1E-31 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CNX65_RS28125 d34066525773e637d6864a06c1e0dbd6 242 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 5 223 25.165 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CNX65_RS28125 d34066525773e637d6864a06c1e0dbd6 242 PIRSF PIRSF006755 4 211 2.0E-39 T 28-03-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 CNX65_RS28125 d34066525773e637d6864a06c1e0dbd6 242 SUPERFAMILY SSF52540 7 205 2.21E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28125 d34066525773e637d6864a06c1e0dbd6 242 Gene3D G3DSA:3.40.50.300 4 215 1.8E-52 T 28-03-2018 CNX65_RS23910 c85272d884ef05a4a14e5191267b07e9 133 Gene3D G3DSA:1.10.10.10 12 120 0.0011 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23910 c85272d884ef05a4a14e5191267b07e9 133 Pfam PF05331 Protein of unknown function (DUF742) 9 133 2.8E-31 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CNX65_RS03290 ebdf984e429a5831babcd1d0c6e5ce22 367 Gene3D G3DSA:2.120.10.30 257 360 6.6E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS03290 ebdf984e429a5831babcd1d0c6e5ce22 367 Gene3D G3DSA:2.120.10.30 26 256 1.6E-37 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS03290 ebdf984e429a5831babcd1d0c6e5ce22 367 Pfam PF07995 Glucose / Sorbosone dehydrogenase 50 358 2.4E-59 T 28-03-2018 IPR012938 Glucose/Sorbosone dehydrogenase CNX65_RS03290 ebdf984e429a5831babcd1d0c6e5ce22 367 SUPERFAMILY SSF50952 33 364 2.35E-36 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CNX65_RS07620 1b903cd1ce3d4331e34ede4eb19450c3 145 Gene3D G3DSA:3.40.1800.10 19 94 3.2E-13 T 28-03-2018 CNX65_RS07620 1b903cd1ce3d4331e34ede4eb19450c3 145 Pfam PF14279 HNH endonuclease 38 84 9.8E-9 T 28-03-2018 IPR029471 HNH endonuclease 5 CNX65_RS07620 1b903cd1ce3d4331e34ede4eb19450c3 145 SMART SM00507 26 79 0.0039 T 28-03-2018 IPR003615 HNH nuclease CNX65_RS11480 3cd48acc58a522f9034bee0d76096659 228 Pfam PF14230 Domain of unknown function (DUF4333) 144 219 6.0E-21 T 28-03-2018 IPR025637 Domain of unknown function DUF4333 CNX65_RS33730 7ab8aa7363b12ebdaf9d33ac4d357cf5 373 SUPERFAMILY SSF53850 55 372 4.52E-84 T 28-03-2018 CNX65_RS33730 7ab8aa7363b12ebdaf9d33ac4d357cf5 373 Gene3D G3DSA:3.40.190.10 233 373 1.9E-19 T 28-03-2018 CNX65_RS33730 7ab8aa7363b12ebdaf9d33ac4d357cf5 373 TIGRFAM TIGR00975 3a0107s03: phosphate ABC transporter, phosphate-binding protein PstS 56 372 2.8E-90 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CNX65_RS33730 7ab8aa7363b12ebdaf9d33ac4d357cf5 373 Gene3D G3DSA:3.40.190.10 54 232 8.2E-33 T 28-03-2018 CNX65_RS33730 7ab8aa7363b12ebdaf9d33ac4d357cf5 373 PIRSF PIRSF002756 7 373 7.3E-118 T 28-03-2018 IPR005673 Phosphate ABC transporter, substrate-binding protein PstS GO:0035435|GO:0042301|GO:0043190 CNX65_RS33730 7ab8aa7363b12ebdaf9d33ac4d357cf5 373 Pfam PF12849 PBP superfamily domain 50 342 8.5E-61 T 28-03-2018 IPR024370 PBP domain CNX65_RS31650 2bff993c398947c245ecb1f0df0b0004 357 Gene3D G3DSA:1.10.3470.10 48 338 2.5E-35 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS31650 2bff993c398947c245ecb1f0df0b0004 357 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 327 2.1E-34 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS11265 8d7ca4a5dc10a3451ce9dc00433be2d3 220 SUPERFAMILY SSF56784 6 192 1.73E-46 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS11265 8d7ca4a5dc10a3451ce9dc00433be2d3 220 Gene3D G3DSA:1.10.150.240 17 76 2.4E-13 T 28-03-2018 IPR023198 Phosphoglycolate phosphatase, domain 2 CNX65_RS11265 8d7ca4a5dc10a3451ce9dc00433be2d3 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 189 1.8E-25 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS11265 8d7ca4a5dc10a3451ce9dc00433be2d3 220 Gene3D G3DSA:3.40.50.1000 77 208 3.7E-27 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS11265 8d7ca4a5dc10a3451ce9dc00433be2d3 220 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 82 189 9.5E-15 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 205 215 1.2E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 26 42 1.2E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 76 95 1.2E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 152 173 1.2E-27 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 12 337 41.562 T 28-03-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 12 336 4.2E-109 T 28-03-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 Gene3D G3DSA:3.40.50.620 2 200 9.9E-76 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 Gene3D G3DSA:1.10.240.10 201 319 4.0E-30 T 28-03-2018 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 21 31 - T 28-03-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 SUPERFAMILY SSF52374 13 336 1.35E-97 T 28-03-2018 CNX65_RS31745 3e8b4e604f005572afa4500a58939007 339 Pfam PF00579 tRNA synthetases class I (W and Y) 12 290 3.1E-83 T 28-03-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 CNX65_RS15640 171c24e656a7124f085208dc1e7c7f48 406 Gene3D G3DSA:3.40.50.150 156 390 1.1E-37 T 28-03-2018 CNX65_RS15640 171c24e656a7124f085208dc1e7c7f48 406 SUPERFAMILY SSF46785 73 150 9.65E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15640 171c24e656a7124f085208dc1e7c7f48 406 PIRSF PIRSF005739 52 380 1.5E-43 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CNX65_RS15640 171c24e656a7124f085208dc1e7c7f48 406 Pfam PF00891 O-methyltransferase 159 376 4.1E-42 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CNX65_RS15640 171c24e656a7124f085208dc1e7c7f48 406 SUPERFAMILY SSF53335 151 385 9.65E-44 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS15640 171c24e656a7124f085208dc1e7c7f48 406 Gene3D G3DSA:1.10.10.10 61 155 8.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30080 8ff55083ebde86f5f57b6baba7294306 333 Pfam PF02733 Dak1 domain 17 327 2.8E-125 T 28-03-2018 IPR004006 DhaK domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 CNX65_RS30080 8ff55083ebde86f5f57b6baba7294306 333 TIGRFAM TIGR02363 dhaK1: dihydroxyacetone kinase, DhaK subunit 1 329 3.9E-143 T 28-03-2018 IPR012736 Dihydroxyacetone kinase DhaK, subunit 1 CNX65_RS30080 8ff55083ebde86f5f57b6baba7294306 333 SUPERFAMILY SSF82549 11 332 8.89E-121 T 28-03-2018 CNX65_RS30080 8ff55083ebde86f5f57b6baba7294306 333 Gene3D G3DSA:3.40.50.10440 11 184 1.8E-67 T 28-03-2018 CNX65_RS30080 8ff55083ebde86f5f57b6baba7294306 333 Gene3D G3DSA:3.30.1180.20 185 333 4.0E-51 T 28-03-2018 CNX65_RS03825 7751a06ea5c4b67aa6734e4008c26d8e 180 Gene3D G3DSA:3.40.50.450 2 180 3.3E-48 T 28-03-2018 CNX65_RS03825 7751a06ea5c4b67aa6734e4008c26d8e 180 Pfam PF03641 Possible lysine decarboxylase 48 177 1.8E-34 T 28-03-2018 IPR031100 LOG family CNX65_RS03825 7751a06ea5c4b67aa6734e4008c26d8e 180 SUPERFAMILY SSF102405 4 177 2.9E-51 T 28-03-2018 CNX65_RS03825 7751a06ea5c4b67aa6734e4008c26d8e 180 TIGRFAM TIGR00730 TIGR00730: TIGR00730 family protein 5 179 7.2E-55 T 28-03-2018 IPR005269 Cytokinin riboside 5'-monophosphate phosphoribohydrolase LOG CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 Gene3D G3DSA:3.30.70.1450 144 218 5.0E-8 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 Pfam PF02254 TrkA-N domain 3 116 1.3E-24 T 28-03-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 Gene3D G3DSA:3.40.50.720 1 118 7.5E-20 T 28-03-2018 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 SUPERFAMILY SSF51735 2 139 2.63E-27 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 PRINTS PR00335 TrkA potassium uptake protein signature 73 87 6.4E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 PRINTS PR00335 TrkA potassium uptake protein signature 19 33 6.4E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 6.4E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 PRINTS PR00335 TrkA potassium uptake protein signature 60 70 6.4E-7 T 28-03-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 Pfam PF02080 TrkA-C domain 148 211 8.0E-9 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS07535 a282423e6b16bdf7282b2349420c4dfc 220 SUPERFAMILY SSF116726 146 210 1.27E-6 T 28-03-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 Gene3D G3DSA:3.40.50.1820 9 270 3.4E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 47 62 4.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 107 120 4.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 93 106 4.8E-6 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 Pfam PF00561 alpha/beta hydrolase fold 22 256 8.3E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00412 Epoxide hydrolase signature 93 106 3.1E-18 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00412 Epoxide hydrolase signature 107 120 3.1E-18 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00412 Epoxide hydrolase signature 212 228 3.1E-18 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00412 Epoxide hydrolase signature 246 268 3.1E-18 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00412 Epoxide hydrolase signature 47 62 3.1E-18 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 PRINTS PR00412 Epoxide hydrolase signature 27 45 3.1E-18 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS25465 e9050517dae844d038ee19d49e1adc00 272 SUPERFAMILY SSF53474 11 269 3.12E-57 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS27705 1230d4a8a159abf90933e284ffa7e466 272 SUPERFAMILY SSF53335 4 243 1.67E-39 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS27705 1230d4a8a159abf90933e284ffa7e466 272 Pfam PF01564 Spermine/spermidine synthase domain 47 205 1.8E-13 T 28-03-2018 CNX65_RS27705 1230d4a8a159abf90933e284ffa7e466 272 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 2 271 15.322 T 28-03-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 CNX65_RS27705 1230d4a8a159abf90933e284ffa7e466 272 Gene3D G3DSA:3.40.50.150 43 247 2.9E-22 T 28-03-2018 CNX65_RS09940 6ff39545150b5728ad9082af4abcea30 219 Pfam PF00702 haloacid dehalogenase-like hydrolase 8 191 1.3E-11 T 28-03-2018 CNX65_RS09940 6ff39545150b5728ad9082af4abcea30 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 7 18 1.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS09940 6ff39545150b5728ad9082af4abcea30 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 146 162 1.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS09940 6ff39545150b5728ad9082af4abcea30 219 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 116 129 1.8E-7 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS09940 6ff39545150b5728ad9082af4abcea30 219 Gene3D G3DSA:3.40.50.1000 2 212 2.3E-21 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS09940 6ff39545150b5728ad9082af4abcea30 219 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 118 191 2.7E-6 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS09940 6ff39545150b5728ad9082af4abcea30 219 SUPERFAMILY SSF56784 8 205 2.42E-30 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34755 355dc29bc2964e59cc866d443b531782 836 Pfam PF00912 Transglycosylase 163 332 7.1E-51 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS34755 355dc29bc2964e59cc866d443b531782 836 Pfam PF00905 Penicillin binding protein transpeptidase domain 431 699 2.0E-20 T 28-03-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 CNX65_RS34755 355dc29bc2964e59cc866d443b531782 836 SUPERFAMILY SSF53955 154 353 1.07E-54 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS34755 355dc29bc2964e59cc866d443b531782 836 Gene3D G3DSA:3.40.710.10 354 793 4.8E-76 T 28-03-2018 CNX65_RS34755 355dc29bc2964e59cc866d443b531782 836 SUPERFAMILY SSF56601 383 758 7.24E-67 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS34755 355dc29bc2964e59cc866d443b531782 836 Gene3D G3DSA:1.10.3810.10 155 351 1.6E-58 T 28-03-2018 IPR001264 Glycosyl transferase, family 51 CNX65_RS09215 7a6527d140f4461c06392986beaeb308 425 Gene3D G3DSA:3.40.190.10 26 230 5.2E-45 T 28-03-2018 CNX65_RS09215 7a6527d140f4461c06392986beaeb308 425 Pfam PF13416 Bacterial extracellular solute-binding protein 46 354 1.5E-43 T 28-03-2018 CNX65_RS09215 7a6527d140f4461c06392986beaeb308 425 Gene3D G3DSA:3.40.190.10 231 363 1.5E-16 T 28-03-2018 CNX65_RS09215 7a6527d140f4461c06392986beaeb308 425 SUPERFAMILY SSF53850 17 417 5.43E-85 T 28-03-2018 CNX65_RS07845 c287c2f2093bff5cd31fc458c5a646ef 81 Pfam PF11239 Protein of unknown function (DUF3040) 1 74 1.4E-14 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CNX65_RS18025 33e989f07a9a971e994298d4b6080aa3 352 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 99 253 3.2E-29 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS18025 33e989f07a9a971e994298d4b6080aa3 352 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 99 254 9.1E-25 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS24625 5300aa1ce96c71dc81d9835cca1ca725 300 SUPERFAMILY SSF51197 15 246 1.56E-50 T 28-03-2018 CNX65_RS24625 5300aa1ce96c71dc81d9835cca1ca725 300 Gene3D G3DSA:2.60.120.620 2 225 3.9E-36 T 28-03-2018 CNX65_RS24625 5300aa1ce96c71dc81d9835cca1ca725 300 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 23 206 9.6E-28 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CNX65_RS31200 ef785e82bb2fe8f7b46cd2567777f416 354 Pfam PF13439 Glycosyltransferase Family 4 16 167 3.3E-8 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS31200 ef785e82bb2fe8f7b46cd2567777f416 354 SUPERFAMILY SSF53756 7 339 8.9E-58 T 28-03-2018 CNX65_RS31200 ef785e82bb2fe8f7b46cd2567777f416 354 Pfam PF00534 Glycosyl transferases group 1 179 323 2.3E-19 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS31200 ef785e82bb2fe8f7b46cd2567777f416 354 Gene3D G3DSA:3.40.50.2000 169 339 8.5E-32 T 28-03-2018 CNX65_RS01835 5b104972a284b1c28331ecf88d185051 134 SUPERFAMILY SSF88723 9 126 6.45E-13 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS01835 5b104972a284b1c28331ecf88d185051 134 Gene3D G3DSA:3.40.50.1010 6 134 4.9E-11 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS13710 e7042afda7597cc9e2ec4f182b7fe727 257 SMART SM00382 29 221 1.1E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13710 e7042afda7597cc9e2ec4f182b7fe727 257 SUPERFAMILY SSF52540 9 225 2.92E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13710 e7042afda7597cc9e2ec4f182b7fe727 257 Gene3D G3DSA:3.40.50.300 3 240 1.2E-59 T 28-03-2018 CNX65_RS13710 e7042afda7597cc9e2ec4f182b7fe727 257 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS13710 e7042afda7597cc9e2ec4f182b7fe727 257 Pfam PF00005 ABC transporter 21 168 3.7E-34 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS07900 6991f970ec7ac7789905aa3a7017776c 751 Pfam PF01569 PAP2 superfamily 67 171 9.9E-19 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS07900 6991f970ec7ac7789905aa3a7017776c 751 SMART SM00014 63 169 4.2E-13 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS07900 6991f970ec7ac7789905aa3a7017776c 751 SUPERFAMILY SSF48317 21 175 9.16E-29 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS07900 6991f970ec7ac7789905aa3a7017776c 751 Gene3D G3DSA:1.20.144.10 9 173 1.9E-26 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS11025 40a90fa3799d1dfe99db2b687b416f7c 334 Pfam PF11887 Cholesterol uptake porter CUP1 of Mce4, putative 161 299 1.1E-6 T 28-03-2018 IPR024516 Mammalian cell entry, C-terminal CNX65_RS11025 40a90fa3799d1dfe99db2b687b416f7c 334 Gene3D G3DSA:3.90.20.10 154 312 1.8E-4 T 28-03-2018 CNX65_RS11025 40a90fa3799d1dfe99db2b687b416f7c 334 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 14 300 1.7E-60 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11025 40a90fa3799d1dfe99db2b687b416f7c 334 Pfam PF02470 MlaD protein 37 111 1.9E-13 T 28-03-2018 IPR003399 Mce/MlaD CNX65_RS27405 c846e20be19aeff2a3d2401d1f0307a4 124 Gene3D G3DSA:3.10.50.40 4 124 2.1E-38 T 28-03-2018 CNX65_RS27405 c846e20be19aeff2a3d2401d1f0307a4 124 SUPERFAMILY SSF54534 16 123 8.05E-37 T 28-03-2018 CNX65_RS27405 c846e20be19aeff2a3d2401d1f0307a4 124 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 30 121 7.5E-29 T 28-03-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain CNX65_RS27570 bef92eff07e1c3b85e29aa54aae42749 385 Pfam PF02653 Branched-chain amino acid transport system / permease component 68 341 2.9E-51 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS27570 bef92eff07e1c3b85e29aa54aae42749 385 Gene3D G3DSA:1.10.3470.10 64 346 8.6E-46 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 SUPERFAMILY SSF140453 143 220 7.85E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 Gene3D G3DSA:1.10.287.850 138 226 1.2E-9 T 28-03-2018 CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 2021 2083 3.5E-20 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 Pfam PF05593 RHS Repeat 1146 1182 1.8E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 Pfam PF05593 RHS Repeat 1167 1203 2.2E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 Pfam PF05593 RHS Repeat 1252 1287 6.1E-8 T 28-03-2018 IPR031325 RHS repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 Pfam PF05593 RHS Repeat 1675 1703 1.2E-5 T 28-03-2018 IPR031325 RHS repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 Pfam PF05593 RHS Repeat 1211 1246 2.7E-5 T 28-03-2018 IPR031325 RHS repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1126 1165 1.3E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1259 1292 3.8E-7 T 28-03-2018 IPR006530 YD repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1167 1206 7.7E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1675 1703 3.3E-5 T 28-03-2018 IPR006530 YD repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1356 1396 1.4E-7 T 28-03-2018 IPR006530 YD repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1296 1333 2.1E-4 T 28-03-2018 IPR006530 YD repeat CNX65_RS14470 f2d266e2eaa9b2f65d4ac4a8cce71a66 2226 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 1209 1250 1.1E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS07500 c8c8c3842e236576c13e38705913fce3 173 Pfam PF11292 Protein of unknown function (DUF3093) 7 146 2.7E-50 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 CNX65_RS10395 f1fafb3da3a38b1accbaeb516c49ce58 336 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 4 301 8.5E-130 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CNX65_RS10395 f1fafb3da3a38b1accbaeb516c49ce58 336 Pfam PF03741 Integral membrane protein TerC family 68 270 3.3E-58 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CNX65_RS17310 e5e532e40393b08de7ab8ce1cb37c12f 197 SUPERFAMILY SSF54593 84 182 1.79E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS17310 e5e532e40393b08de7ab8ce1cb37c12f 197 Gene3D G3DSA:3.10.180.10 78 188 4.6E-7 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS17310 e5e532e40393b08de7ab8ce1cb37c12f 197 Gene3D G3DSA:3.10.180.10 1 77 0.031 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 SMART SM00852 178 317 4.1E-24 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 Pfam PF00994 Probable molybdopterin binding domain 179 316 1.6E-16 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 SUPERFAMILY SSF63867 326 402 2.09E-17 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 Gene3D G3DSA:2.170.190.11 55 139 1.9E-30 T 28-03-2018 CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 Pfam PF03454 MoeA C-terminal region (domain IV) 331 402 7.8E-20 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 SUPERFAMILY SSF63882 1 174 2.22E-45 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 Gene3D G3DSA:3.90.105.10 22 54 9.1E-5 T 28-03-2018 CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 SUPERFAMILY SSF53218 175 322 1.1E-30 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 Gene3D G3DSA:2.40.340.10 328 401 3.9E-22 T 28-03-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 Gene3D G3DSA:3.40.980.10 148 324 7.0E-41 T 28-03-2018 IPR001453 MoaB/Mog domain CNX65_RS03120 22cbfebe351e298509982902e0080bb3 407 Pfam PF03453 MoeA N-terminal region (domain I and II) 3 165 4.0E-40 T 28-03-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS14215 e2ff2bb63940a37148da5470f53cd0e0 340 Gene3D G3DSA:3.20.20.70 5 320 1.2E-30 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS14215 e2ff2bb63940a37148da5470f53cd0e0 340 SUPERFAMILY SSF102114 7 302 1.07E-42 T 28-03-2018 CNX65_RS14215 e2ff2bb63940a37148da5470f53cd0e0 340 Pfam PF04055 Radical SAM superfamily 14 159 3.1E-16 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS29295 24f9b2f189e5e83d68c87d3e4b1af110 195 Pfam PF02620 Uncharacterized ACR, COG1399 72 182 3.3E-29 T 28-03-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD CNX65_RS02365 100711e8da69ad5206220a2bf03530a5 157 Pfam PF01967 MoaC family 15 148 2.9E-49 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CNX65_RS02365 100711e8da69ad5206220a2bf03530a5 157 Gene3D G3DSA:3.30.70.640 2 156 1.1E-60 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CNX65_RS02365 100711e8da69ad5206220a2bf03530a5 157 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 149 8.1E-58 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CNX65_RS02365 100711e8da69ad5206220a2bf03530a5 157 SUPERFAMILY SSF55040 11 153 1.31E-52 T 28-03-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 Reactome: R-HSA-947581 CNX65_RS02365 100711e8da69ad5206220a2bf03530a5 157 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase accessory protein [moaC]. 2 156 33.929 T 28-03-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 Reactome: R-HSA-947581 CNX65_RS05195 d3ccbb81e49d05516218a60591b7e41e 159 Gene3D G3DSA:1.10.260.40 5 81 9.4E-14 T 28-03-2018 CNX65_RS05195 d3ccbb81e49d05516218a60591b7e41e 159 SUPERFAMILY SSF47413 7 73 1.07E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS05195 d3ccbb81e49d05516218a60591b7e41e 159 Pfam PF13560 Helix-turn-helix domain 12 70 3.0E-9 T 28-03-2018 CNX65_RS05195 d3ccbb81e49d05516218a60591b7e41e 159 SMART SM00530 15 72 1.1E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS22655 57f4af90436ce03e725dadac45ad61a8 357 Gene3D G3DSA:1.10.150.130 39 153 5.8E-9 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS22655 57f4af90436ce03e725dadac45ad61a8 357 SUPERFAMILY SSF56349 45 330 4.12E-29 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS22655 57f4af90436ce03e725dadac45ad61a8 357 Pfam PF00589 Phage integrase family 162 291 6.7E-9 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS22655 57f4af90436ce03e725dadac45ad61a8 357 Gene3D G3DSA:1.10.443.10 154 334 6.7E-20 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS06960 751f5cca673205ea0a74f186f3fab5d4 187 Gene3D G3DSA:3.40.630.30 11 186 3.5E-20 T 28-03-2018 CNX65_RS06960 751f5cca673205ea0a74f186f3fab5d4 187 SUPERFAMILY SSF55729 21 183 5.85E-16 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS06960 751f5cca673205ea0a74f186f3fab5d4 187 Pfam PF00583 Acetyltransferase (GNAT) family 30 161 3.0E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS07405 6256fbb4a4b88f7e5c99b93bce26aff7 498 SUPERFAMILY SSF53335 154 309 2.41E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS07405 6256fbb4a4b88f7e5c99b93bce26aff7 498 Pfam PF05175 Methyltransferase small domain 148 233 2.0E-13 T 28-03-2018 IPR007848 Methyltransferase small domain GO:0008168 CNX65_RS07405 6256fbb4a4b88f7e5c99b93bce26aff7 498 Gene3D G3DSA:3.40.50.150 140 331 2.9E-18 T 28-03-2018 CNX65_RS07405 6256fbb4a4b88f7e5c99b93bce26aff7 498 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 224 230 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CNX65_RS08370 53c8f1758da4e1da95491020b7d5d8ac 553 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 83 446 2.9E-56 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS08370 53c8f1758da4e1da95491020b7d5d8ac 553 Gene3D G3DSA:3.40.190.10 160 291 1.2E-26 T 28-03-2018 CNX65_RS08370 53c8f1758da4e1da95491020b7d5d8ac 553 PIRSF PIRSF002741 1 512 2.0E-63 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS08370 53c8f1758da4e1da95491020b7d5d8ac 553 Gene3D G3DSA:3.90.76.10 56 159 3.0E-16 T 28-03-2018 CNX65_RS08370 53c8f1758da4e1da95491020b7d5d8ac 553 SUPERFAMILY SSF53850 33 529 1.25E-86 T 28-03-2018 CNX65_RS08370 53c8f1758da4e1da95491020b7d5d8ac 553 Gene3D G3DSA:3.10.105.10 292 509 7.5E-43 T 28-03-2018 CNX65_RS13015 04702bf98a9b07faf459971c746709a8 364 Pfam PF14031 Putative serine dehydratase domain 243 349 2.8E-17 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CNX65_RS13015 04702bf98a9b07faf459971c746709a8 364 Pfam PF01168 Alanine racemase, N-terminal domain 11 227 1.8E-25 T 28-03-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 CNX65_RS13015 04702bf98a9b07faf459971c746709a8 364 SMART SM01119 243 350 5.9E-28 T 28-03-2018 IPR026956 D-serine dehydratase-like domain CNX65_RS13015 04702bf98a9b07faf459971c746709a8 364 Gene3D G3DSA:3.20.20.10 12 225 2.4E-35 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS13015 04702bf98a9b07faf459971c746709a8 364 SUPERFAMILY SSF51419 11 235 8.72E-28 T 28-03-2018 IPR029066 PLP-binding barrel CNX65_RS32170 ee8593d7910f03cb0d7ccb0813bed1d4 366 Pfam PF12697 Alpha/beta hydrolase family 84 341 2.6E-23 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS32170 ee8593d7910f03cb0d7ccb0813bed1d4 366 Gene3D G3DSA:3.40.50.1820 54 353 5.9E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS32170 ee8593d7910f03cb0d7ccb0813bed1d4 366 SUPERFAMILY SSF53474 54 348 1.34E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16680 a8a471ca8d133d641a8b7c6409765dd1 272 SMART SM00342 108 190 8.5E-11 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16680 a8a471ca8d133d641a8b7c6409765dd1 272 Gene3D G3DSA:1.10.10.60 145 204 1.6E-8 T 28-03-2018 CNX65_RS16680 a8a471ca8d133d641a8b7c6409765dd1 272 Pfam PF12833 Helix-turn-helix domain 115 192 1.5E-17 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS16680 a8a471ca8d133d641a8b7c6409765dd1 272 Gene3D G3DSA:1.10.10.60 72 144 1.5E-6 T 28-03-2018 CNX65_RS16680 a8a471ca8d133d641a8b7c6409765dd1 272 SUPERFAMILY SSF46689 144 193 3.76E-7 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 Gene3D G3DSA:1.10.230.10 228 319 2.5E-22 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 ProSitePatterns PS00480 Citrate synthase signature. 248 260 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 PRINTS PR00143 Citrate synthase signature 166 181 9.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 PRINTS PR00143 Citrate synthase signature 320 334 9.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 PRINTS PR00143 Citrate synthase signature 241 261 9.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 PRINTS PR00143 Citrate synthase signature 188 216 9.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 PRINTS PR00143 Citrate synthase signature 300 316 9.4E-24 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 SUPERFAMILY SSF48256 9 361 6.28E-93 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 Gene3D G3DSA:1.10.580.10 1 70 5.2E-13 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 Gene3D G3DSA:1.10.580.10 98 227 4.0E-35 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 Pfam PF00285 Citrate synthase, C-terminal domain 13 61 5.2E-9 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02590 8116f938ebc153e89040facbfd4da16d 371 Pfam PF00285 Citrate synthase, C-terminal domain 115 349 2.6E-72 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS34115 f561f1caf95d34cd1c7083c1ff3404d2 329 Pfam PF16868 NMT1-like family 48 323 4.2E-69 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS34115 f561f1caf95d34cd1c7083c1ff3404d2 329 Gene3D G3DSA:3.40.190.10 154 327 6.2E-28 T 28-03-2018 CNX65_RS34115 f561f1caf95d34cd1c7083c1ff3404d2 329 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 323 7.4E-82 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS34115 f561f1caf95d34cd1c7083c1ff3404d2 329 SUPERFAMILY SSF53850 45 325 4.48E-63 T 28-03-2018 CNX65_RS34115 f561f1caf95d34cd1c7083c1ff3404d2 329 Gene3D G3DSA:3.40.190.10 40 153 7.2E-22 T 28-03-2018 CNX65_RS07230 7f008a93dbffd344d8cfc27fad77322f 332 TIGRFAM TIGR01430 aden_deam: adenosine deaminase 8 328 5.2E-76 T 28-03-2018 IPR006330 Adenosine/adenine deaminase GO:0019239 Reactome: R-HSA-74217 CNX65_RS07230 7f008a93dbffd344d8cfc27fad77322f 332 Pfam PF00962 Adenosine/AMP deaminase 8 325 2.0E-71 T 28-03-2018 IPR001365 Adenosine/AMP deaminase domain GO:0019239 Reactome: R-HSA-74217 CNX65_RS07230 7f008a93dbffd344d8cfc27fad77322f 332 Gene3D G3DSA:3.20.20.140 3 331 6.1E-78 T 28-03-2018 CNX65_RS07230 7f008a93dbffd344d8cfc27fad77322f 332 SUPERFAMILY SSF51556 4 331 6.81E-74 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 Gene3D G3DSA:3.40.50.300 497 747 4.1E-75 T 28-03-2018 CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 SMART SM00382 533 719 1.4E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 Pfam PF00005 ABC transporter 524 673 7.3E-31 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 Pfam PF00664 ABC transporter transmembrane region 188 459 2.6E-10 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 Gene3D G3DSA:1.20.1560.10 161 494 2.7E-29 T 28-03-2018 CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 SUPERFAMILY SSF90123 170 492 3.79E-34 T 28-03-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0006810|GO:0016021|GO:0042626|GO:0055085 CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 ProSitePatterns PS00211 ABC transporters family signature. 645 659 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS16120 9e7712ec50d655ee362c5b9d4c9ceef8 748 SUPERFAMILY SSF52540 501 743 2.26E-87 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17055 c87859787d0858095621ef6187dd8422 345 SMART SM00382 121 314 2.0E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS17055 c87859787d0858095621ef6187dd8422 345 SUPERFAMILY SSF52540 92 338 4.9E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS17055 c87859787d0858095621ef6187dd8422 345 ProSitePatterns PS00211 ABC transporters family signature. 237 251 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS17055 c87859787d0858095621ef6187dd8422 345 Gene3D G3DSA:3.40.50.300 85 343 1.1E-59 T 28-03-2018 CNX65_RS17055 c87859787d0858095621ef6187dd8422 345 Pfam PF00005 ABC transporter 113 268 1.1E-23 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS26995 abdb559e32a70be151fd541caca21c1b 269 Gene3D G3DSA:1.10.3720.10 3 256 9.2E-20 T 28-03-2018 CNX65_RS26995 abdb559e32a70be151fd541caca21c1b 269 SUPERFAMILY SSF161098 60 242 1.44E-23 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS26995 abdb559e32a70be151fd541caca21c1b 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 248 9.0E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS34760 18f835876985e1ed6b343b9e680a76dc 519 Pfam PF09594 Glycosyltransferase family 87 173 403 5.6E-13 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CNX65_RS34760 18f835876985e1ed6b343b9e680a76dc 519 PIRSF PIRSF010361 24 505 2.1E-161 T 28-03-2018 IPR016570 Uncharacterised conserved protein UCP010361, membrane CNX65_RS31325 b584bf6e7fa029641b40199c8f6b0586 184 Pfam PF04138 GtrA-like protein 28 158 4.7E-24 T 28-03-2018 IPR007267 GtrA-like protein GO:0000271|GO:0006810|GO:0016021 CNX65_RS30880 2dd900311b6ad7733989f35aa1f90d6d 519 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 216 222 - T 28-03-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 CNX65_RS30880 2dd900311b6ad7733989f35aa1f90d6d 519 Gene3D G3DSA:3.40.50.150 96 315 5.2E-22 T 28-03-2018 CNX65_RS30880 2dd900311b6ad7733989f35aa1f90d6d 519 Pfam PF01861 Protein of unknown function DUF43 103 285 8.7E-30 T 28-03-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal CNX65_RS30880 2dd900311b6ad7733989f35aa1f90d6d 519 SUPERFAMILY SSF53335 163 276 1.71E-12 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 Pfam PF01494 FAD binding domain 7 338 5.2E-76 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 SUPERFAMILY SSF51905 5 170 2.51E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 SUPERFAMILY SSF51905 260 368 2.51E-66 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 Gene3D G3DSA:3.50.50.60 1 384 1.4E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 306 324 3.9E-45 T 28-03-2018 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 273 288 3.9E-45 T 28-03-2018 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 324 340 3.9E-45 T 28-03-2018 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 288 304 3.9E-45 T 28-03-2018 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 149 164 3.9E-45 T 28-03-2018 CNX65_RS18405 4031524ec010d78e874d70e32888d11f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 3.9E-45 T 28-03-2018 CNX65_RS27810 d9e7cbaaa8cb5f40e0987c46b2cbe38a 221 Pfam PF09335 SNARE associated Golgi protein 40 163 5.1E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 SMART SM00304 400 452 5.8E-10 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 SMART SM00283 460 714 4.1E-50 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 Gene3D G3DSA:3.30.450.20 67 369 1.4E-12 T 28-03-2018 CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 Gene3D G3DSA:1.10.287.1060 398 495 0.022 T 28-03-2018 CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 SUPERFAMILY SSF103190 135 248 6.28E-15 T 28-03-2018 IPR029151 Periplasmic sensor domain-like CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 SUPERFAMILY SSF58104 420 713 6.15E-60 T 28-03-2018 CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 Gene3D G3DSA:1.10.287.950 496 715 2.8E-46 T 28-03-2018 CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 521 685 1.2E-29 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 Pfam PF17201 Cache 3/Cache 2 fusion domain 46 371 1.4E-81 T 28-03-2018 IPR033462 Cache 3/Cache 2 fusion domain CNX65_RS00905 14e38e2b82c5a4b7f175ee0f79e73c4a 715 Pfam PF00672 HAMP domain 400 449 3.3E-9 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS06905 a371e0e1d70d46fca9580a8ac4931f15 462 TIGRFAM TIGR01358 DAHP_synth_II: 3-deoxy-7-phosphoheptulonate synthase 27 461 1.2E-215 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CNX65_RS06905 a371e0e1d70d46fca9580a8ac4931f15 462 Pfam PF01474 Class-II DAHP synthetase family 32 457 1.3E-189 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CNX65_RS06905 a371e0e1d70d46fca9580a8ac4931f15 462 SUPERFAMILY SSF51569 5 461 2.27E-193 T 28-03-2018 CNX65_RS06905 a371e0e1d70d46fca9580a8ac4931f15 462 Gene3D G3DSA:3.20.20.70 130 407 3.0E-5 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS08070 09d606aff3cf6688b6e219b26fb78861 383 Gene3D G3DSA:3.60.10.10 127 377 2.3E-18 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS08070 09d606aff3cf6688b6e219b26fb78861 383 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 141 370 5.3E-6 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS08070 09d606aff3cf6688b6e219b26fb78861 383 SUPERFAMILY SSF56219 131 371 4.84E-21 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS18155 350594838a0bdc246a290906b23d474c 173 Pfam PF13671 AAA domain 4 126 1.3E-8 T 28-03-2018 CNX65_RS18155 350594838a0bdc246a290906b23d474c 173 Gene3D G3DSA:3.40.50.300 2 173 6.2E-15 T 28-03-2018 CNX65_RS18155 350594838a0bdc246a290906b23d474c 173 SUPERFAMILY SSF52540 2 172 9.82E-13 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09880 a3cbc611057d04a6bd602c9e28cc9f1d 542 Pfam PF13416 Bacterial extracellular solute-binding protein 80 388 2.9E-17 T 28-03-2018 CNX65_RS09880 a3cbc611057d04a6bd602c9e28cc9f1d 542 SUPERFAMILY SSF53850 23 30 2.09E-71 T 28-03-2018 CNX65_RS09880 a3cbc611057d04a6bd602c9e28cc9f1d 542 SUPERFAMILY SSF53850 57 537 2.09E-71 T 28-03-2018 CNX65_RS09880 a3cbc611057d04a6bd602c9e28cc9f1d 542 Gene3D G3DSA:3.40.190.10 183 539 1.1E-36 T 28-03-2018 CNX65_RS11430 a64487f0061724de3a5c1598b85bea0c 452 TIGRFAM TIGR03686 pupylate_PafA: Pup--protein ligase 3 452 8.1E-237 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CNX65_RS11430 a64487f0061724de3a5c1598b85bea0c 452 Pfam PF03136 Pup-ligase protein 4 422 3.6E-160 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CNX65_RS11430 a64487f0061724de3a5c1598b85bea0c 452 PIRSF PIRSF018077 1 452 4.5E-184 T 28-03-2018 IPR004347 Pup ligase/deamidase GO:0010498|GO:0019941 CNX65_RS11430 a64487f0061724de3a5c1598b85bea0c 452 Hamap MF_02111 Pup--protein ligase [pafA]. 1 452 51.272 T 28-03-2018 IPR022279 Pup--protein ligase GO:0010498|GO:0016879|GO:0019941 CNX65_RS10490 69d604bfe320a8b9508f7695611784e0 216 Gene3D G3DSA:1.10.3720.10 6 211 8.0E-22 T 28-03-2018 CNX65_RS10490 69d604bfe320a8b9508f7695611784e0 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 205 2.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS10490 69d604bfe320a8b9508f7695611784e0 216 SUPERFAMILY SSF161098 11 198 6.15E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09440 0419ddb3c605ca7c0bfe9a0ca6c48b28 1104 Pfam PF13569 Domain of unknown function (DUF4132) 842 1020 1.1E-52 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS32755 69360233884f2abf1a5045003e2168c6 315 SUPERFAMILY SSF56747 2 195 1.9E-29 T 28-03-2018 CNX65_RS32755 69360233884f2abf1a5045003e2168c6 315 SMART SM00943 7 197 3.3E-46 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS32755 69360233884f2abf1a5045003e2168c6 315 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 7 196 4.6E-41 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS08180 61a45cb91eaff7e93e47eaef5fa7c8ec 321 Gene3D G3DSA:3.40.50.10140 1 158 2.3E-13 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS08180 61a45cb91eaff7e93e47eaef5fa7c8ec 321 Pfam PF08357 SEFIR domain 8 138 7.3E-13 T 28-03-2018 IPR013568 SEFIR domain CNX65_RS08180 61a45cb91eaff7e93e47eaef5fa7c8ec 321 SUPERFAMILY SSF52200 7 136 7.46E-8 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS08180 61a45cb91eaff7e93e47eaef5fa7c8ec 321 Pfam PF08305 NPCBM/NEW2 domain 213 297 1.9E-4 T 28-03-2018 IPR013222 Glycosyl hydrolase family 98, putative carbohydrate-binding module CNX65_RS08180 61a45cb91eaff7e93e47eaef5fa7c8ec 321 SUPERFAMILY SSF49785 212 296 9.35E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS09015 fefa5653408ea2265db2176476ae6465 275 SUPERFAMILY SSF81298 11 62 6.8E-6 T 28-03-2018 IPR035099 Anthrax toxin, edema factor, C-terminal KEGG: 00230+4.6.1.1 CNX65_RS09945 08a060e57837aee2542374beca186a38 196 Gene3D G3DSA:1.20.120.20 8 163 5.6E-13 T 28-03-2018 CNX65_RS09945 08a060e57837aee2542374beca186a38 196 SUPERFAMILY SSF58113 12 139 7.32E-5 T 28-03-2018 CNX65_RS09945 08a060e57837aee2542374beca186a38 196 Pfam PF12277 Protein of unknown function (DUF3618) 9 53 5.1E-13 T 28-03-2018 IPR022062 Protein of unknown function DUF3618 CNX65_RS29850 6c1aecb978ce5de38a85889c35eec737 259 Gene3D G3DSA:1.10.12.10 216 251 6.5E-14 T 28-03-2018 IPR014748 Crontonase, C-terminal CNX65_RS29850 6c1aecb978ce5de38a85889c35eec737 259 SUPERFAMILY SSF52096 4 254 3.08E-81 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS29850 6c1aecb978ce5de38a85889c35eec737 259 Gene3D G3DSA:3.90.226.10 5 215 2.5E-70 T 28-03-2018 CNX65_RS29850 6c1aecb978ce5de38a85889c35eec737 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 251 4.3E-66 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS07525 52adcf0d05e8156f131fb38d9ca1d1e7 262 PIRSF PIRSF010219 1 218 1.4E-65 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CNX65_RS07525 52adcf0d05e8156f131fb38d9ca1d1e7 262 Pfam PF11361 Protein of unknown function (DUF3159) 20 204 7.5E-61 T 28-03-2018 IPR016566 Uncharacterised conserved protein UCP010219 CNX65_RS22305 21b376ebd394eccb5cb59af34fbad1eb 590 Pfam PF07690 Major Facilitator Superfamily 222 489 1.9E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS22305 21b376ebd394eccb5cb59af34fbad1eb 590 Gene3D G3DSA:1.20.1250.20 409 590 3.7E-14 T 28-03-2018 CNX65_RS22305 21b376ebd394eccb5cb59af34fbad1eb 590 Gene3D G3DSA:1.20.1250.20 201 385 7.4E-15 T 28-03-2018 CNX65_RS22305 21b376ebd394eccb5cb59af34fbad1eb 590 SUPERFAMILY SSF103473 210 588 1.26E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS29795 5f27ed6dc979c711a4007ce6ae6087e2 262 Gene3D G3DSA:3.30.1330.60 142 256 6.6E-7 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS29795 5f27ed6dc979c711a4007ce6ae6087e2 262 SUPERFAMILY SSF103088 163 255 6.8E-7 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS23175 79a7988461a6a9774d4e5fff2545eed5 334 Gene3D G3DSA:3.20.20.70 12 325 9.4E-4 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS00880 f6aaa8d6fa368a2c24f55543a0834965 821 Gene3D G3DSA:3.60.10.10 494 796 1.1E-31 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS00880 f6aaa8d6fa368a2c24f55543a0834965 821 Gene3D G3DSA:2.60.40.1260 7 140 9.1E-11 T 28-03-2018 IPR001322 Lamin Tail Domain CNX65_RS00880 f6aaa8d6fa368a2c24f55543a0834965 821 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 497 788 4.5E-11 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS00880 f6aaa8d6fa368a2c24f55543a0834965 821 Pfam PF00932 Lamin Tail Domain 28 134 4.3E-8 T 28-03-2018 IPR001322 Lamin Tail Domain CNX65_RS00880 f6aaa8d6fa368a2c24f55543a0834965 821 SUPERFAMILY SSF56219 494 795 2.62E-32 T 28-03-2018 IPR005135 Endonuclease/exonuclease/phosphatase CNX65_RS06090 37f13adb3daae64986916af294cc526f 346 Gene3D G3DSA:3.20.20.70 3 343 1.6E-51 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS06090 37f13adb3daae64986916af294cc526f 346 SUPERFAMILY SSF51412 5 338 1.53E-53 T 28-03-2018 CNX65_RS06090 37f13adb3daae64986916af294cc526f 346 Pfam PF03060 Nitronate monooxygenase 7 329 7.2E-79 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CNX65_RS31540 d84e08e51b0e3a14af2f338ab8c1aecf 68 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 37 4.0E-7 T 28-03-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 CNX65_RS31540 d84e08e51b0e3a14af2f338ab8c1aecf 68 Gene3D G3DSA:1.10.1220.10 2 44 9.7E-10 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CNX65_RS31540 d84e08e51b0e3a14af2f338ab8c1aecf 68 SUPERFAMILY SSF47598 2 38 5.56E-6 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CNX65_RS23285 46c98ad04209109eda3618337ea67448 297 SUPERFAMILY SSF53474 5 239 1.02E-25 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23285 46c98ad04209109eda3618337ea67448 297 Pfam PF12740 Chlorophyllase enzyme 22 135 3.4E-8 T 28-03-2018 IPR017395 Chlorophyllase GO:0015996|GO:0047746 KEGG: 00860+3.1.1.14|MetaCyc: PWY-5098|MetaCyc: PWY-6927|MetaCyc: PWY-7164 CNX65_RS23285 46c98ad04209109eda3618337ea67448 297 Gene3D G3DSA:3.40.50.1820 2 289 1.3E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19050 f5577ef62a18dc15d075068061e1d5f4 492 Gene3D G3DSA:3.50.50.60 8 490 3.0E-37 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19050 f5577ef62a18dc15d075068061e1d5f4 492 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 12 490 1.3E-145 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 CNX65_RS19050 f5577ef62a18dc15d075068061e1d5f4 492 Pfam PF01593 Flavin containing amine oxidoreductase 19 488 5.7E-40 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS19050 f5577ef62a18dc15d075068061e1d5f4 492 SUPERFAMILY SSF51905 11 319 2.13E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19050 f5577ef62a18dc15d075068061e1d5f4 492 SUPERFAMILY SSF51905 448 488 2.13E-59 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19050 f5577ef62a18dc15d075068061e1d5f4 492 PRINTS PR00419 Adrenodoxin reductase family signature 11 33 2.4E-6 T 28-03-2018 CNX65_RS19050 f5577ef62a18dc15d075068061e1d5f4 492 PRINTS PR00419 Adrenodoxin reductase family signature 34 47 2.4E-6 T 28-03-2018 CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 Pfam PF05593 RHS Repeat 472 509 1.5E-8 T 28-03-2018 IPR031325 RHS repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 Pfam PF05593 RHS Repeat 577 613 4.2E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 Pfam PF05593 RHS Repeat 641 673 2.0E-5 T 28-03-2018 IPR031325 RHS repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 Pfam PF05593 RHS Repeat 518 550 6.4E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 Pfam PF05593 RHS Repeat 430 467 2.1E-7 T 28-03-2018 IPR031325 RHS repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 Gene3D G3DSA:2.120.10.30 259 772 2.8E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 SUPERFAMILY SSF63829 588 632 1.77E-5 T 28-03-2018 CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 SUPERFAMILY SSF63829 400 553 1.77E-5 T 28-03-2018 CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 430 469 3.7E-8 T 28-03-2018 IPR006530 YD repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 619 657 8.2E-8 T 28-03-2018 IPR006530 YD repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 472 511 7.1E-7 T 28-03-2018 IPR006530 YD repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 517 554 3.8E-8 T 28-03-2018 IPR006530 YD repeat CNX65_RS02910 03e1f50923656c45805af0a00c498273 1161 TIGRFAM TIGR01643 YD_repeat_2x: YD repeat (two copies) 577 618 3.4E-6 T 28-03-2018 IPR006530 YD repeat CNX65_RS15985 1089c3b874cdfadafcf5d2b64fd59aae 230 Gene3D G3DSA:1.10.357.10 1 230 1.4E-33 T 28-03-2018 CNX65_RS15985 1089c3b874cdfadafcf5d2b64fd59aae 230 SUPERFAMILY SSF46689 3 76 1.45E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS15985 1089c3b874cdfadafcf5d2b64fd59aae 230 SUPERFAMILY SSF48498 79 156 3.34E-5 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS15985 1089c3b874cdfadafcf5d2b64fd59aae 230 Pfam PF13305 WHG domain 89 146 4.1E-6 T 28-03-2018 IPR025996 WHG domain CNX65_RS15985 1089c3b874cdfadafcf5d2b64fd59aae 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 56 6.3E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS13940 72a734e39a3ddec8396767870311bb02 216 Pfam PF03734 L,D-transpeptidase catalytic domain 36 207 1.4E-8 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CNX65_RS16480 eb361ba7d0f30364ef308e8ce77daf0e 33 TIGRFAM TIGR02115 potass_kdpF: K+-transporting ATPase, F subunit 10 33 9.1E-11 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CNX65_RS16480 eb361ba7d0f30364ef308e8ce77daf0e 33 Pfam PF09604 F subunit of K+-transporting ATPase (Potass_KdpF) 10 33 1.3E-10 T 28-03-2018 IPR011726 K+ transporting P-type ATPase, F subunit GO:0005886|GO:0008556|GO:0043462 CNX65_RS27530 8ebcd17731b6e024826688411b5ee43b 206 Gene3D G3DSA:3.40.50.720 9 139 2.5E-4 T 28-03-2018 CNX65_RS24445 65067e885056d679b3cb62a0dfe882ec 366 Gene3D G3DSA:3.40.50.2000 180 342 7.3E-38 T 28-03-2018 CNX65_RS24445 65067e885056d679b3cb62a0dfe882ec 366 Gene3D G3DSA:3.40.50.2000 12 179 2.1E-15 T 28-03-2018 CNX65_RS24445 65067e885056d679b3cb62a0dfe882ec 366 Pfam PF13439 Glycosyltransferase Family 4 16 173 1.8E-18 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS24445 65067e885056d679b3cb62a0dfe882ec 366 SUPERFAMILY SSF53756 10 358 1.73E-65 T 28-03-2018 CNX65_RS24445 65067e885056d679b3cb62a0dfe882ec 366 Pfam PF00534 Glycosyl transferases group 1 183 322 6.3E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS02595 c60ccce94ea8eb6862c1260873a44884 276 SUPERFAMILY SSF52540 4 219 7.04E-59 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02595 c60ccce94ea8eb6862c1260873a44884 276 SMART SM00382 29 215 1.5E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS02595 c60ccce94ea8eb6862c1260873a44884 276 Gene3D G3DSA:3.40.50.300 1 243 7.3E-63 T 28-03-2018 CNX65_RS02595 c60ccce94ea8eb6862c1260873a44884 276 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS02595 c60ccce94ea8eb6862c1260873a44884 276 Pfam PF00005 ABC transporter 21 158 6.3E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS28225 adf46d17df51cb134e1dd747ea358ed0 234 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 8 231 1.4E-73 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CNX65_RS28225 adf46d17df51cb134e1dd747ea358ed0 234 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 13 232 1.1E-53 T 28-03-2018 IPR003730 Multi-copper polyphenol oxidoreductase CNX65_RS28225 adf46d17df51cb134e1dd747ea358ed0 234 Gene3D G3DSA:3.60.140.10 1 234 1.3E-86 T 28-03-2018 CNX65_RS28225 adf46d17df51cb134e1dd747ea358ed0 234 SUPERFAMILY SSF64438 3 232 2.38E-74 T 28-03-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic CNX65_RS29835 f2c355addc12e007cb3d77ab949a64b0 310 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 4 297 4.3E-80 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CNX65_RS29835 f2c355addc12e007cb3d77ab949a64b0 310 Gene3D G3DSA:3.90.245.10 1 309 6.7E-96 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CNX65_RS29835 f2c355addc12e007cb3d77ab949a64b0 310 SUPERFAMILY SSF53590 4 307 6.15E-84 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CNX65_RS01905 e2da15d11390e5ae72198d5e4de7d5d7 478 Gene3D G3DSA:3.40.50.2000 267 458 6.9E-43 T 28-03-2018 CNX65_RS01905 e2da15d11390e5ae72198d5e4de7d5d7 478 Pfam PF00982 Glycosyltransferase family 20 11 472 3.1E-151 T 28-03-2018 IPR001830 Glycosyl transferase, family 20 GO:0003824|GO:0005992 CNX65_RS01905 e2da15d11390e5ae72198d5e4de7d5d7 478 SUPERFAMILY SSF53756 10 472 1.07E-142 T 28-03-2018 CNX65_RS01905 e2da15d11390e5ae72198d5e4de7d5d7 478 Gene3D G3DSA:3.40.50.2000 7 266 3.9E-90 T 28-03-2018 CNX65_RS25545 34a8d77af717772b09742fbe4c71d97c 325 Gene3D G3DSA:1.10.260.40 29 100 1.5E-6 T 28-03-2018 CNX65_RS01455 65b90eeeb10f42ad4547fb190d96701a 201 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 20 170 7.2E-10 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS01455 65b90eeeb10f42ad4547fb190d96701a 201 SMART SM00943 19 175 1.4E-5 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS25840 675bf14aa8d34c1edae5fd46d8b52b28 119 Gene3D G3DSA:2.60.40.1310 1 86 6.2E-6 T 28-03-2018 CNX65_RS02930 7f0c8e5c4a3bc11589c2c332c3567e23 247 SUPERFAMILY SSF47413 4 61 3.1E-5 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS02930 7f0c8e5c4a3bc11589c2c332c3567e23 247 Gene3D G3DSA:1.10.260.40 1 69 1.3E-8 T 28-03-2018 CNX65_RS18255 7386bfcc966f475dcdc32dd451ec7536 205 Gene3D G3DSA:3.30.565.10 76 205 1.5E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18255 7386bfcc966f475dcdc32dd451ec7536 205 SUPERFAMILY SSF55874 108 195 9.36E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18255 7386bfcc966f475dcdc32dd451ec7536 205 Pfam PF13581 Histidine kinase-like ATPase domain 87 198 4.6E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS30190 96b1b4730ce53ddd9f78e8ebb094cebb 121 SUPERFAMILY SSF51344 4 84 9.81E-21 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30190 96b1b4730ce53ddd9f78e8ebb094cebb 121 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 4 104 1.6E-25 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30190 96b1b4730ce53ddd9f78e8ebb094cebb 121 Gene3D G3DSA:2.60.15.10 1 90 1.2E-26 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30190 96b1b4730ce53ddd9f78e8ebb094cebb 121 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 84 1.7E-26 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30190 96b1b4730ce53ddd9f78e8ebb094cebb 121 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 84 8.0E-24 T 28-03-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS30190 96b1b4730ce53ddd9f78e8ebb094cebb 121 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 116 18.166 T 28-03-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 CNX65_RS10765 09b0b6152f800d14aae506d0e7127f52 182 SUPERFAMILY SSF48498 79 177 5.11E-23 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS10765 09b0b6152f800d14aae506d0e7127f52 182 Gene3D G3DSA:1.10.357.10 1 182 1.2E-27 T 28-03-2018 CNX65_RS10765 09b0b6152f800d14aae506d0e7127f52 182 SUPERFAMILY SSF46689 2 69 1.8E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS10765 09b0b6152f800d14aae506d0e7127f52 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 9 22 3.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10765 09b0b6152f800d14aae506d0e7127f52 182 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 30 53 3.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS10765 09b0b6152f800d14aae506d0e7127f52 182 Pfam PF00440 Bacterial regulatory proteins, tetR family 9 55 1.2E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS03605 69b5c7927fb3709eb898eb86e66b2c5e 350 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 16 323 2.2E-142 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CNX65_RS03605 69b5c7927fb3709eb898eb86e66b2c5e 350 PIRSF PIRSF004532 14 334 1.4E-147 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CNX65_RS03605 69b5c7927fb3709eb898eb86e66b2c5e 350 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 16 327 1.5E-114 T 28-03-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 CNX65_RS03605 69b5c7927fb3709eb898eb86e66b2c5e 350 Gene3D G3DSA:3.30.540.10 169 335 2.4E-55 T 28-03-2018 CNX65_RS03605 69b5c7927fb3709eb898eb86e66b2c5e 350 Gene3D G3DSA:3.30.540.10 13 168 2.8E-53 T 28-03-2018 CNX65_RS03605 69b5c7927fb3709eb898eb86e66b2c5e 350 SUPERFAMILY SSF56655 14 326 9.89E-114 T 28-03-2018 CNX65_RS10695 f0e92253345efdf98e703679b2b1142d 463 Pfam PF01979 Amidohydrolase family 52 438 3.6E-26 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS10695 f0e92253345efdf98e703679b2b1142d 463 Gene3D G3DSA:3.20.20.140 72 405 3.3E-104 T 28-03-2018 CNX65_RS10695 f0e92253345efdf98e703679b2b1142d 463 SUPERFAMILY SSF51556 56 384 5.3E-111 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS10695 f0e92253345efdf98e703679b2b1142d 463 SUPERFAMILY SSF51338 2 71 4.32E-10 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS10695 f0e92253345efdf98e703679b2b1142d 463 SUPERFAMILY SSF51338 362 457 8.64E-35 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS10695 f0e92253345efdf98e703679b2b1142d 463 TIGRFAM TIGR02033 D-hydantoinase: dihydropyrimidinase 4 456 1.2E-178 T 28-03-2018 IPR011778 Hydantoinase/dihydropyrimidinase GO:0005737 Reactome: R-HSA-399956 CNX65_RS10695 f0e92253345efdf98e703679b2b1142d 463 Gene3D G3DSA:2.30.40.10 2 71 7.3E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS24400 c515f5c0ae7640935a594f4ad9088222 385 Pfam PF13641 Glycosyltransferase like family 2 43 254 4.4E-23 T 28-03-2018 CNX65_RS24400 c515f5c0ae7640935a594f4ad9088222 385 SUPERFAMILY SSF53448 37 255 2.39E-35 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS24400 c515f5c0ae7640935a594f4ad9088222 385 Gene3D G3DSA:3.90.550.10 19 265 2.2E-37 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS04595 1206b265c5adbe4ecdfc648e4f83a705 175 Pfam PF01863 Protein of unknown function DUF45 83 150 6.1E-21 T 28-03-2018 IPR002725 Protein of unknown function DUF45 CNX65_RS13350 7b313f2f0cab66c2252d8532bcde1751 229 Gene3D G3DSA:3.40.50.2300 1 124 2.0E-38 T 28-03-2018 CNX65_RS13350 7b313f2f0cab66c2252d8532bcde1751 229 Pfam PF00486 Transcriptional regulatory protein, C terminal 150 224 5.3E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS13350 7b313f2f0cab66c2252d8532bcde1751 229 SMART SM00448 1 112 2.5E-42 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS13350 7b313f2f0cab66c2252d8532bcde1751 229 Gene3D G3DSA:1.10.10.10 125 229 1.0E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13350 7b313f2f0cab66c2252d8532bcde1751 229 SUPERFAMILY SSF52172 2 182 1.76E-41 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS13350 7b313f2f0cab66c2252d8532bcde1751 229 SMART SM00862 149 224 1.1E-24 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS13350 7b313f2f0cab66c2252d8532bcde1751 229 Pfam PF00072 Response regulator receiver domain 3 113 2.2E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 Pfam PF12802 MarR family 26 87 4.4E-13 T 28-03-2018 CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 1.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 1.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 1.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 PRINTS PR00598 Bacterial regulatory protein MarR family signature 114 134 1.8E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 SUPERFAMILY SSF46785 6 139 1.78E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 SMART SM00347 21 124 5.6E-19 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS00725 2dc66d1202e147c383c3bd6d7cfe3e52 143 Gene3D G3DSA:1.10.10.10 2 143 1.4E-24 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS31125 12985709c919e783f5d8a4b4a2900c33 63 Gene3D G3DSA:2.20.25.10 10 60 3.0E-13 T 28-03-2018 CNX65_RS31125 12985709c919e783f5d8a4b4a2900c33 63 SUPERFAMILY SSF158997 2 59 2.22E-12 T 28-03-2018 CNX65_RS31125 12985709c919e783f5d8a4b4a2900c33 63 Pfam PF03966 Trm112p-like protein 4 48 2.6E-5 T 28-03-2018 IPR005651 Uncharacterised protein family UPF0434/Trm112 CNX65_RS09515 67867621626ad3612cf77cb2e6abf82b 345 Pfam PF00881 Nitroreductase family 132 317 2.7E-5 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS09515 67867621626ad3612cf77cb2e6abf82b 345 SUPERFAMILY SSF55469 19 93 7.72E-10 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09515 67867621626ad3612cf77cb2e6abf82b 345 SUPERFAMILY SSF55469 122 187 1.86E-12 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09515 67867621626ad3612cf77cb2e6abf82b 345 SUPERFAMILY SSF55469 244 330 1.86E-12 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09515 67867621626ad3612cf77cb2e6abf82b 345 Gene3D G3DSA:3.40.109.30 18 94 8.1E-15 T 28-03-2018 CNX65_RS09515 67867621626ad3612cf77cb2e6abf82b 345 Gene3D G3DSA:3.40.109.10 118 339 4.6E-30 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS08185 47b8a6147eb9fbd41160826a5f0fa78b 189 Gene3D G3DSA:3.40.50.10140 1 164 1.5E-12 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS08185 47b8a6147eb9fbd41160826a5f0fa78b 189 Pfam PF13676 TIR domain 6 94 7.5E-8 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS08185 47b8a6147eb9fbd41160826a5f0fa78b 189 SUPERFAMILY SSF52200 2 93 1.2E-10 T 28-03-2018 IPR000157 Toll/interleukin-1 receptor homology (TIR) domain GO:0005515|GO:0007165 CNX65_RS34960 443823211db0d40a5bad1a0f1fc32951 88 SUPERFAMILY SSF46894 12 80 1.8E-12 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS34960 443823211db0d40a5bad1a0f1fc32951 88 SMART SM00421 17 74 4.5E-8 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34960 443823211db0d40a5bad1a0f1fc32951 88 Pfam PF00196 Bacterial regulatory proteins, luxR family 19 74 1.1E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS34960 443823211db0d40a5bad1a0f1fc32951 88 Gene3D G3DSA:1.10.10.10 3 84 4.0E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08725 1e6b872a6e12cd224706dfa64c2ff203 407 Pfam PF07690 Major Facilitator Superfamily 27 256 8.3E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS08725 1e6b872a6e12cd224706dfa64c2ff203 407 Gene3D G3DSA:1.20.1250.20 17 208 7.0E-19 T 28-03-2018 CNX65_RS08725 1e6b872a6e12cd224706dfa64c2ff203 407 Gene3D G3DSA:1.20.1250.20 217 407 1.4E-16 T 28-03-2018 CNX65_RS08725 1e6b872a6e12cd224706dfa64c2ff203 407 SUPERFAMILY SSF103473 19 400 1.83E-40 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS22045 5d0ac3b502dfdbcf955b64c33609aefb 176 SUPERFAMILY SSF49777 16 171 4.84E-49 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CNX65_RS22045 5d0ac3b502dfdbcf955b64c33609aefb 176 Pfam PF01161 Phosphatidylethanolamine-binding protein 39 171 1.1E-37 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CNX65_RS22045 5d0ac3b502dfdbcf955b64c33609aefb 176 Gene3D G3DSA:3.90.280.10 2 174 1.7E-50 T 28-03-2018 IPR008914 Phosphatidylethanolamine-binding protein CNX65_RS22045 5d0ac3b502dfdbcf955b64c33609aefb 176 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 33 169 8.1E-36 T 28-03-2018 IPR005247 YbhB/YbcL CNX65_RS21075 d707185ff7042ef936951e12e58c17cf 241 Gene3D G3DSA:3.40.250.10 122 235 2.3E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21075 d707185ff7042ef936951e12e58c17cf 241 Gene3D G3DSA:1.10.1200.10 3 118 2.8E-8 T 28-03-2018 CNX65_RS21075 d707185ff7042ef936951e12e58c17cf 241 ProSitePatterns PS00380 Rhodanese signature 1. 149 160 - T 28-03-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350 CNX65_RS21075 d707185ff7042ef936951e12e58c17cf 241 SUPERFAMILY SSF52821 121 229 2.88E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21075 d707185ff7042ef936951e12e58c17cf 241 SMART SM00450 124 221 5.2E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21075 d707185ff7042ef936951e12e58c17cf 241 Pfam PF00581 Rhodanese-like domain 127 217 4.6E-11 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS21075 d707185ff7042ef936951e12e58c17cf 241 SUPERFAMILY SSF47336 7 95 4.32E-7 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 170 195 - T 28-03-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 Reactome: R-HSA-71403 CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 SUPERFAMILY SSF52283 2 168 1.45E-40 T 28-03-2018 CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 SUPERFAMILY SSF51735 137 312 4.36E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 Gene3D G3DSA:3.40.50.720 1 194 1.4E-37 T 28-03-2018 CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 SMART SM01003 4 137 1.5E-39 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 137 4.4E-32 T 28-03-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 141 362 3.4E-68 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 SMART SM01002 146 307 1.9E-74 T 28-03-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain CNX65_RS06445 eac7223d9eab7fc2047d764f084ca16a 369 Gene3D G3DSA:3.40.50.720 195 369 3.5E-40 T 28-03-2018 CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 SMART SM00382 24 207 2.1E-18 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 Gene3D G3DSA:2.40.50.100 268 337 1.9E-13 T 28-03-2018 CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 ProSitePatterns PS00211 ABC transporters family signature. 130 144 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 Pfam PF00005 ABC transporter 19 158 4.5E-32 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 Gene3D G3DSA:3.40.50.300 17 236 5.2E-63 T 28-03-2018 CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 SUPERFAMILY SSF50331 232 342 6.8E-16 T 28-03-2018 IPR008995 Molybdate/tungstate binding, C-terminal CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 Pfam PF03459 TOBE domain 282 339 6.2E-10 T 28-03-2018 IPR005116 Transport-associated OB, type 1 CNX65_RS09730 32ace6e95ced252cb2d71719fc8e7827 344 SUPERFAMILY SSF52540 9 232 2.96E-68 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08925 1f542b882c4c73fb168e5f414d51cc31 83 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 5 56 1.2E-8 T 28-03-2018 CNX65_RS08925 1f542b882c4c73fb168e5f414d51cc31 83 SUPERFAMILY SSF143120 2 81 1.23E-21 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS08925 1f542b882c4c73fb168e5f414d51cc31 83 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 2 73 1.6E-17 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS08925 1f542b882c4c73fb168e5f414d51cc31 83 Gene3D G3DSA:3.40.1620.10 2 59 3.9E-15 T 28-03-2018 CNX65_RS01815 2b99202ea3b89133de8d9bd56445dba0 278 Pfam PF00950 ABC 3 transport family 18 269 1.8E-45 T 28-03-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 CNX65_RS01815 2b99202ea3b89133de8d9bd56445dba0 278 SUPERFAMILY SSF81345 9 266 1.83E-32 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS01815 2b99202ea3b89133de8d9bd56445dba0 278 Gene3D G3DSA:1.10.3470.10 4 278 2.2E-24 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 SUPERFAMILY SSF51735 5 243 8.55E-72 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 2.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 2.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 2.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 191 2.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.6E-36 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.1E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 243 9.3E-57 T 28-03-2018 CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 184 1.2E-5 T 28-03-2018 CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 Gene3D G3DSA:3.40.50.720 2 38 3.9E-7 T 28-03-2018 CNX65_RS15980 cc7d0856bd1059f2a28f8af47c3938f2 244 Gene3D G3DSA:3.40.50.720 39 244 4.8E-57 T 28-03-2018 CNX65_RS31375 478d578fb9c47031c0dbfb70b8a02f53 253 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 15 249 1.8E-44 T 28-03-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780 CNX65_RS31375 478d578fb9c47031c0dbfb70b8a02f53 253 SUPERFAMILY SSF55681 14 186 2.24E-44 T 28-03-2018 CNX65_RS31375 478d578fb9c47031c0dbfb70b8a02f53 253 SUPERFAMILY SSF50037 205 249 1.37E-6 T 28-03-2018 IPR008988 Transcriptional repressor, C-terminal CNX65_RS31375 478d578fb9c47031c0dbfb70b8a02f53 253 Gene3D G3DSA:2.30.30.100 203 251 9.7E-15 T 28-03-2018 CNX65_RS31375 478d578fb9c47031c0dbfb70b8a02f53 253 Pfam PF03099 Biotin/lipoate A/B protein ligase family 25 132 3.2E-15 T 28-03-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 CNX65_RS31375 478d578fb9c47031c0dbfb70b8a02f53 253 Gene3D G3DSA:3.30.930.10 1 202 4.2E-52 T 28-03-2018 CNX65_RS07410 5fc3e23c2ad142dbd66e1b7c14c9afe9 506 Gene3D G3DSA:1.10.10.60 422 472 4.2E-8 T 28-03-2018 CNX65_RS07410 5fc3e23c2ad142dbd66e1b7c14c9afe9 506 Gene3D G3DSA:3.30.450.40 118 238 0.0012 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS07410 5fc3e23c2ad142dbd66e1b7c14c9afe9 506 Pfam PF13556 PucR C-terminal helix-turn-helix domain 437 493 1.9E-18 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS06180 016f6cd44a825022847a81bdceece3bf 404 Gene3D G3DSA:3.20.20.70 27 343 6.0E-50 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS06180 016f6cd44a825022847a81bdceece3bf 404 Pfam PF04055 Radical SAM superfamily 34 208 2.0E-20 T 28-03-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 CNX65_RS06180 016f6cd44a825022847a81bdceece3bf 404 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 32 363 7.1E-70 T 28-03-2018 IPR004559 Coproporphyrinogen III oxidase, oxygen-independent related GO:0004109|GO:0005737|GO:0006779|GO:0055114 CNX65_RS06180 016f6cd44a825022847a81bdceece3bf 404 SUPERFAMILY SSF102114 21 403 9.55E-103 T 28-03-2018 CNX65_RS06180 016f6cd44a825022847a81bdceece3bf 404 SMART SM00729 29 254 1.2E-53 T 28-03-2018 IPR006638 Elongator protein 3/MiaB/NifB GO:0003824|GO:0051536 CNX65_RS15080 dd36c638159a627518fc02fdafcec335 291 Gene3D G3DSA:3.40.50.150 8 291 7.3E-30 T 28-03-2018 CNX65_RS15080 dd36c638159a627518fc02fdafcec335 291 Pfam PF13649 Methyltransferase domain 60 156 1.6E-14 T 28-03-2018 CNX65_RS15080 dd36c638159a627518fc02fdafcec335 291 SUPERFAMILY SSF53335 38 245 9.36E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 SUPERFAMILY SSF51905 2 165 8.2E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 SUPERFAMILY SSF51905 257 351 8.2E-67 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 3 25 2.6E-46 T 28-03-2018 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 144 159 2.6E-46 T 28-03-2018 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 2.6E-46 T 28-03-2018 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 2.6E-46 T 28-03-2018 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 2.6E-46 T 28-03-2018 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 2.6E-46 T 28-03-2018 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 Pfam PF01494 FAD binding domain 2 336 1.6E-92 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS10050 c53b5b5d6dd6cce1da439385cbc961a7 476 Gene3D G3DSA:3.50.50.60 2 380 1.9E-68 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS01005 f5e76f6812f4f81f1b9696bf539988d9 215 Gene3D G3DSA:3.40.109.10 18 207 2.3E-39 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS01005 f5e76f6812f4f81f1b9696bf539988d9 215 SUPERFAMILY SSF55469 23 203 3.01E-40 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS01005 f5e76f6812f4f81f1b9696bf539988d9 215 Pfam PF00881 Nitroreductase family 86 169 6.8E-10 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS01005 f5e76f6812f4f81f1b9696bf539988d9 215 Pfam PF00881 Nitroreductase family 27 83 3.3E-8 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS13785 25ad3f8b77ae17549c57338c5e254554 261 SUPERFAMILY SSF52540 5 229 3.55E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS13785 25ad3f8b77ae17549c57338c5e254554 261 Pfam PF00005 ABC transporter 23 169 3.6E-27 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS13785 25ad3f8b77ae17549c57338c5e254554 261 Gene3D G3DSA:3.40.50.300 2 238 2.2E-59 T 28-03-2018 CNX65_RS13785 25ad3f8b77ae17549c57338c5e254554 261 SMART SM00382 29 225 3.5E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13785 25ad3f8b77ae17549c57338c5e254554 261 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS30340 1324ca208b5d010aaab2fa62ee1d791b 590 Pfam PF03235 Protein of unknown function DUF262 15 255 9.2E-23 T 28-03-2018 IPR004919 Domain of unknown function DUF262 CNX65_RS14290 e2f89cebd676b609ab2c8378330cd610 417 Gene3D G3DSA:3.40.190.10 32 157 1.2E-19 T 28-03-2018 CNX65_RS14290 e2f89cebd676b609ab2c8378330cd610 417 Gene3D G3DSA:3.40.190.10 158 362 8.0E-41 T 28-03-2018 CNX65_RS14290 e2f89cebd676b609ab2c8378330cd610 417 SUPERFAMILY SSF53850 33 405 2.93E-66 T 28-03-2018 CNX65_RS14290 e2f89cebd676b609ab2c8378330cd610 417 Pfam PF13416 Bacterial extracellular solute-binding protein 47 356 3.9E-33 T 28-03-2018 CNX65_RS01755 b3bba4abdd6d3a8be929db3363bd52ba 168 Gene3D G3DSA:3.90.1140.10 2 167 2.9E-5 T 28-03-2018 CNX65_RS17950 b2a691ee0bde72d4c383e21c20fe64ab 212 Pfam PF09335 SNARE associated Golgi protein 32 160 5.8E-17 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS17335 c7186ddc72ecf415aa30dd72586be77d 184 SUPERFAMILY SSF55729 11 167 3.24E-29 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS17335 c7186ddc72ecf415aa30dd72586be77d 184 Gene3D G3DSA:3.40.630.30 10 177 8.8E-29 T 28-03-2018 CNX65_RS17335 c7186ddc72ecf415aa30dd72586be77d 184 Pfam PF13302 Acetyltransferase (GNAT) domain 18 160 3.6E-21 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS09075 f0f558b5b190b43bcf6495e18fd76369 244 Gene3D G3DSA:3.30.750.24 1 120 3.2E-9 T 28-03-2018 IPR002645 STAS domain CNX65_RS09075 f0f558b5b190b43bcf6495e18fd76369 244 SUPERFAMILY SSF55874 155 242 4.91E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS09075 f0f558b5b190b43bcf6495e18fd76369 244 SUPERFAMILY SSF52091 4 115 2.55E-8 T 28-03-2018 IPR002645 STAS domain CNX65_RS09075 f0f558b5b190b43bcf6495e18fd76369 244 Gene3D G3DSA:3.30.565.10 121 244 2.2E-9 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS29385 799550a1487de90247340f935dc13166 151 SUPERFAMILY SSF46785 7 148 2.45E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29385 799550a1487de90247340f935dc13166 151 Gene3D G3DSA:1.10.10.10 2 151 9.6E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29385 799550a1487de90247340f935dc13166 151 SMART SM00347 32 135 3.8E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS29385 799550a1487de90247340f935dc13166 151 Pfam PF12802 MarR family 37 98 9.2E-14 T 28-03-2018 CNX65_RS32815 5a2c400d57c329a473495c0ded9e7527 137 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 48 132 1.1E-18 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32815 5a2c400d57c329a473495c0ded9e7527 137 SUPERFAMILY SSF56770 5 135 9.81E-42 T 28-03-2018 CNX65_RS32815 5a2c400d57c329a473495c0ded9e7527 137 Gene3D G3DSA:3.40.50.700 10 137 8.6E-29 T 28-03-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS21880 86631f1a57b00b3ae3ac4ed1e9b06897 162 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 9.4E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21880 86631f1a57b00b3ae3ac4ed1e9b06897 162 Gene3D G3DSA:1.10.10.60 52 152 7.1E-11 T 28-03-2018 CNX65_RS21880 86631f1a57b00b3ae3ac4ed1e9b06897 162 Gene3D G3DSA:1.10.10.60 7 51 1.4E-11 T 28-03-2018 CNX65_RS21880 86631f1a57b00b3ae3ac4ed1e9b06897 162 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 3.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21880 86631f1a57b00b3ae3ac4ed1e9b06897 162 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 3.0E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS21880 86631f1a57b00b3ae3ac4ed1e9b06897 162 SUPERFAMILY SSF46689 14 87 4.36E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS19435 aa60bf34d337859f92d530e938891a18 355 Pfam PF01758 Sodium Bile acid symporter family 61 257 3.0E-63 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CNX65_RS19435 aa60bf34d337859f92d530e938891a18 355 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 16 344 6.7E-135 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CNX65_RS19435 aa60bf34d337859f92d530e938891a18 355 PIRSF PIRSF005508 5 355 4.6E-138 T 28-03-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 SMART SM00028 162 195 0.047 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 SMART SM00028 202 235 110.0 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 Pfam PF12770 CHAT domain 638 864 4.9E-28 T 28-03-2018 IPR024983 CHAT domain CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 Gene3D G3DSA:1.25.40.10 19 102 0.02 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 Gene3D G3DSA:1.25.40.10 116 255 2.5E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 SUPERFAMILY SSF48452 120 228 7.27E-11 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 Gene3D G3DSA:1.25.40.10 256 494 0.15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29660 bbd024d2f3f1c274b5d8f2804e031d13 880 Gene3D G3DSA:3.40.50.1460 717 867 2.2E-9 T 28-03-2018 CNX65_RS06800 afbfea23ba2ae486e01d68b7ba898f23 270 SUPERFAMILY SSF46626 136 226 9.31E-28 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CNX65_RS06800 afbfea23ba2ae486e01d68b7ba898f23 270 Gene3D G3DSA:1.10.760.10 40 144 1.6E-16 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CNX65_RS06800 afbfea23ba2ae486e01d68b7ba898f23 270 PIRSF PIRSF000007 1 270 2.0E-116 T 28-03-2018 IPR009152 Cytochrome bc1 complex, cytochrome c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 CNX65_RS06800 afbfea23ba2ae486e01d68b7ba898f23 270 Gene3D G3DSA:1.10.760.10 145 240 2.0E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CNX65_RS06800 afbfea23ba2ae486e01d68b7ba898f23 270 SUPERFAMILY SSF46626 24 136 6.17E-18 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CNX65_RS06800 afbfea23ba2ae486e01d68b7ba898f23 270 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 151 224 8.4E-13 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CNX65_RS06800 afbfea23ba2ae486e01d68b7ba898f23 270 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 55 130 8.4E-9 T 28-03-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-611105 CNX65_RS06930 85ad805af64b80af54c6df56a7e0bd29 356 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 237 249 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CNX65_RS06930 85ad805af64b80af54c6df56a7e0bd29 356 Pfam PF00348 Polyprenyl synthetase 44 301 4.3E-47 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CNX65_RS06930 85ad805af64b80af54c6df56a7e0bd29 356 SUPERFAMILY SSF48576 36 355 9.66E-74 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS06930 85ad805af64b80af54c6df56a7e0bd29 356 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 93 107 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CNX65_RS06930 85ad805af64b80af54c6df56a7e0bd29 356 Gene3D G3DSA:1.10.600.10 8 356 5.2E-85 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS11735 36c30e05db4c7a49b5b6142816eabea7 71 Pfam PF09360 Iron-binding zinc finger CDGSH type 15 60 3.7E-16 T 28-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CNX65_RS11735 36c30e05db4c7a49b5b6142816eabea7 71 SMART SM00704 21 65 5.1E-10 T 28-03-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 CNX65_RS19990 a9338fcec0e0aac51a5d906677ce96dc 250 Pfam PF06271 RDD family 90 226 2.1E-16 T 28-03-2018 IPR010432 RDD CNX65_RS01635 a24f2bd33a9af9feb11961569927283c 150 Pfam PF11377 Protein of unknown function (DUF3180) 9 144 8.2E-41 T 28-03-2018 IPR021517 Protein of unknown function DUF3180 CNX65_RS08060 823078584e5b6a8f924271d195c4b0dd 476 Gene3D G3DSA:3.90.1150.10 325 474 6.2E-13 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS08060 823078584e5b6a8f924271d195c4b0dd 476 Pfam PF00202 Aminotransferase class-III 44 455 1.8E-62 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS08060 823078584e5b6a8f924271d195c4b0dd 476 Gene3D G3DSA:3.90.1150.10 11 179 2.3E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS08060 823078584e5b6a8f924271d195c4b0dd 476 Gene3D G3DSA:3.40.640.10 181 324 9.6E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS08060 823078584e5b6a8f924271d195c4b0dd 476 SUPERFAMILY SSF53383 24 457 5.43E-79 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS28115 d8a46093b5cb9ec744de210b131bd851 65 ProDom PD028237 MB1616 ML1221 CGL0073 RV1590/MT1625 30 65 6.0E-8 T 28-03-2018 CNX65_RS23130 b16a53e8cd366a678a1d077a383564ad 309 SUPERFAMILY SSF51735 117 279 6.5E-29 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23130 b16a53e8cd366a678a1d077a383564ad 309 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 28 93 6.3E-8 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS23130 b16a53e8cd366a678a1d077a383564ad 309 Gene3D G3DSA:3.40.50.720 140 295 8.8E-27 T 28-03-2018 CNX65_RS23130 b16a53e8cd366a678a1d077a383564ad 309 Gene3D G3DSA:3.90.180.10 1 139 1.2E-39 T 28-03-2018 CNX65_RS23130 b16a53e8cd366a678a1d077a383564ad 309 Pfam PF13602 Zinc-binding dehydrogenase 188 307 1.1E-13 T 28-03-2018 CNX65_RS23130 b16a53e8cd366a678a1d077a383564ad 309 SUPERFAMILY SSF50129 1 149 2.59E-36 T 28-03-2018 IPR011032 GroES-like CNX65_RS23130 b16a53e8cd366a678a1d077a383564ad 309 SMART SM00829 10 307 1.2E-13 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 Pfam PF00106 short chain dehydrogenase 17 187 3.3E-40 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 153 172 1.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 80 91 1.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 1.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 12 29 1.8E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 Gene3D G3DSA:3.40.50.720 4 269 1.3E-53 T 28-03-2018 CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 SUPERFAMILY SSF51735 5 267 3.57E-55 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 133 141 3.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 80 91 3.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS20525 6bee549dbb9682cb2d02f39f12aa008f 289 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 153 172 3.2E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS27290 c82c678185637a121e01c778f803bb79 321 Pfam PF00294 pfkB family carbohydrate kinase 9 289 3.7E-48 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS27290 c82c678185637a121e01c778f803bb79 321 SUPERFAMILY SSF53613 9 289 6.86E-67 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS27290 c82c678185637a121e01c778f803bb79 321 Gene3D G3DSA:3.40.1190.20 7 312 1.1E-60 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS28545 5ca0f6980a32660446c04b2303419afb 150 Gene3D G3DSA:1.25.40.10 13 149 1.9E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS28930 98becd14c77b32b6a19ce09bcaf5cffb 282 Gene3D G3DSA:1.10.3720.10 11 278 5.1E-40 T 28-03-2018 CNX65_RS28930 98becd14c77b32b6a19ce09bcaf5cffb 282 SUPERFAMILY SSF161098 20 273 5.76E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS28930 98becd14c77b32b6a19ce09bcaf5cffb 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 273 5.9E-10 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS34350 55c3e675f81ef600fd89f94f53573a4f 109 SUPERFAMILY SSF103481 5 106 9.15E-16 T 28-03-2018 CNX65_RS34350 55c3e675f81ef600fd89f94f53573a4f 109 Pfam PF00893 Small Multidrug Resistance protein 4 94 1.3E-24 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CNX65_RS22990 150d1b0ee314a3a4875b91654e74eb1d 300 Pfam PF00487 Fatty acid desaturase 39 257 1.0E-18 T 28-03-2018 IPR005804 Fatty acid desaturase domain GO:0006629 CNX65_RS22990 150d1b0ee314a3a4875b91654e74eb1d 300 PRINTS PR00075 Fatty acid desaturase family 1 signature 61 81 2.8E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CNX65_RS22990 150d1b0ee314a3a4875b91654e74eb1d 300 PRINTS PR00075 Fatty acid desaturase family 1 signature 241 255 2.8E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CNX65_RS22990 150d1b0ee314a3a4875b91654e74eb1d 300 PRINTS PR00075 Fatty acid desaturase family 1 signature 198 219 2.8E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CNX65_RS22990 150d1b0ee314a3a4875b91654e74eb1d 300 PRINTS PR00075 Fatty acid desaturase family 1 signature 38 60 2.8E-17 T 28-03-2018 IPR015876 Acyl-CoA desaturase GO:0016717|GO:0055114 Reactome: R-HSA-75105 CNX65_RS19040 61403ffbf4ce6db9cb5c6fdf3c5544b2 140 Gene3D G3DSA:3.30.450.30 17 135 3.1E-17 T 28-03-2018 CNX65_RS19040 61403ffbf4ce6db9cb5c6fdf3c5544b2 140 SMART SM00960 19 113 1.7E-7 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS19040 61403ffbf4ce6db9cb5c6fdf3c5544b2 140 SUPERFAMILY SSF103196 18 131 1.52E-13 T 28-03-2018 CNX65_RS19040 61403ffbf4ce6db9cb5c6fdf3c5544b2 140 Pfam PF03259 Roadblock/LC7 domain 29 111 3.7E-8 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS18700 8eddcd5d7e5ef8dc82f07443eff46b50 371 Pfam PF01699 Sodium/calcium exchanger protein 227 368 2.0E-13 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CNX65_RS18700 8eddcd5d7e5ef8dc82f07443eff46b50 371 Pfam PF01699 Sodium/calcium exchanger protein 40 191 7.9E-13 T 28-03-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 CNX65_RS04295 ee899629007984a718be5efe6acf995c 389 TIGRFAM TIGR02678 TIGR02678: TIGR02678 family protein 17 358 8.2E-38 T 28-03-2018 IPR013494 Conserved hypothetical protein CHP02678 CNX65_RS04295 ee899629007984a718be5efe6acf995c 389 Pfam PF09661 Protein of unknown function (DUF2398) 17 359 7.7E-93 T 28-03-2018 IPR013494 Conserved hypothetical protein CHP02678 CNX65_RS22885 46fb0cd94206415ea206d519da51eeff 513 Pfam PF02361 Cobalt transport protein 267 473 8.4E-27 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CNX65_RS05865 c1ea1cedfe563f1972c55aac40009c0e 183 Gene3D G3DSA:1.10.10.10 94 182 3.5E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05865 c1ea1cedfe563f1972c55aac40009c0e 183 Pfam PF04542 Sigma-70 region 2 28 96 3.9E-13 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS05865 c1ea1cedfe563f1972c55aac40009c0e 183 SUPERFAMILY SSF88659 116 180 5.61E-13 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS05865 c1ea1cedfe563f1972c55aac40009c0e 183 Pfam PF04545 Sigma-70, region 4 129 176 1.8E-8 T 28-03-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS05865 c1ea1cedfe563f1972c55aac40009c0e 183 Gene3D G3DSA:1.10.1740.10 12 93 2.1E-16 T 28-03-2018 CNX65_RS05865 c1ea1cedfe563f1972c55aac40009c0e 183 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 26 178 2.2E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS05865 c1ea1cedfe563f1972c55aac40009c0e 183 SUPERFAMILY SSF88946 16 107 7.46E-16 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS07340 377adcd092695e3a04ab9191eab1d241 59 Pfam PF04149 Domain of unknown function (DUF397) 6 56 1.3E-18 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS17880 aefd94f6e0b53759af561c01f25cf046 160 SUPERFAMILY SSF55729 8 136 3.19E-19 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS17880 aefd94f6e0b53759af561c01f25cf046 160 Pfam PF13302 Acetyltransferase (GNAT) domain 12 131 9.3E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS17880 aefd94f6e0b53759af561c01f25cf046 160 Gene3D G3DSA:3.40.630.30 1 151 9.8E-19 T 28-03-2018 CNX65_RS25120 efb37258b6309b32945b245bc5dd87a9 500 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 87 465 6.4E-16 T 28-03-2018 IPR021145 Portal protein CNX65_RS20285 29bf4bb49bd8699c1b69966da5d413e0 129 SUPERFAMILY SSF54427 7 120 1.31E-14 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS20285 29bf4bb49bd8699c1b69966da5d413e0 129 Gene3D G3DSA:3.10.450.50 4 129 9.9E-15 T 28-03-2018 CNX65_RS20285 29bf4bb49bd8699c1b69966da5d413e0 129 Pfam PF12680 SnoaL-like domain 14 105 1.6E-10 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 Gene3D G3DSA:1.20.1250.20 242 440 2.5E-14 T 28-03-2018 CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 Gene3D G3DSA:1.20.1250.20 40 237 4.1E-16 T 28-03-2018 CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 PRINTS PR01988 Putative bacilysin exporter bacE signature 301 318 3.4E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 PRINTS PR01988 Putative bacilysin exporter bacE signature 342 365 3.4E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 PRINTS PR01988 Putative bacilysin exporter bacE signature 182 203 3.4E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 PRINTS PR01988 Putative bacilysin exporter bacE signature 405 428 3.4E-5 T 28-03-2018 IPR022324 Bacilysin exporter BacE, putative GO:0016020|GO:0042891 CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 SUPERFAMILY SSF103473 48 435 9.42E-35 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS12135 1192527dabdbc3c540ba5148e52a8f3b 449 Pfam PF05977 Transmembrane secretion effector 41 436 8.1E-33 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS21775 dd0621f0d290a175325fad1bcfb1eeb9 202 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 15 190 9.0E-31 T 28-03-2018 IPR003740 Uncharacterised membrane protein YitT CNX65_RS03325 6b252bcb9f9f95150c4d3962e389f81e 127 Gene3D G3DSA:1.25.40.10 3 66 4.3E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS03325 6b252bcb9f9f95150c4d3962e389f81e 127 Gene3D G3DSA:1.25.40.10 67 125 1.7E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS03325 6b252bcb9f9f95150c4d3962e389f81e 127 SUPERFAMILY SSF48452 8 114 1.07E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS03325 6b252bcb9f9f95150c4d3962e389f81e 127 SMART SM00028 73 106 3.4 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS03325 6b252bcb9f9f95150c4d3962e389f81e 127 SMART SM00028 39 72 0.0035 T 28-03-2018 IPR019734 Tetratricopeptide repeat GO:0005515 CNX65_RS03325 6b252bcb9f9f95150c4d3962e389f81e 127 Pfam PF13432 Tetratricopeptide repeat 43 104 9.9E-10 T 28-03-2018 CNX65_RS15100 1f0fba4de886b222fe99c5311b2efa21 155 Gene3D G3DSA:1.20.120.450 1 155 3.1E-30 T 28-03-2018 CNX65_RS15100 1f0fba4de886b222fe99c5311b2efa21 155 Pfam PF04978 Protein of unknown function (DUF664) 19 151 5.0E-36 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CNX65_RS15100 1f0fba4de886b222fe99c5311b2efa21 155 SUPERFAMILY SSF109854 1 150 1.15E-34 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS01875 9aabaa08050b72f6334320d68655e883 250 SUPERFAMILY SSF110087 197 238 5.36E-6 T 28-03-2018 IPR007410 Copper chaperone PCuAC CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 Pfam PF00082 Subtilase family 316 572 1.5E-60 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 357 367 - T 28-03-2018 IPR022398 Peptidase S8, subtilisin, His-active site CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 SUPERFAMILY SSF52743 299 583 3.93E-82 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 523 533 - T 28-03-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 PRINTS PR00723 Subtilisin serine protease family (S8) signature 353 366 7.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 PRINTS PR00723 Subtilisin serine protease family (S8) signature 316 335 7.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 PRINTS PR00723 Subtilisin serine protease family (S8) signature 522 538 7.9E-21 T 28-03-2018 IPR015500 Peptidase S8, subtilisin-related CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 321 332 - T 28-03-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 Gene3D G3DSA:3.40.50.200 281 587 2.0E-86 T 28-03-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 CNX65_RS22825 9a93b195f1170d80f30c4955ba5485c1 1174 Gene3D G3DSA:2.60.40.10 590 681 1.1E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 SUPERFAMILY SSF46785 1 100 1.58E-30 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 Pfam PF01022 Bacterial regulatory protein, arsR family 10 55 2.9E-15 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 SMART SM00418 3 81 4.7E-27 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 Gene3D G3DSA:1.10.10.10 1 102 1.6E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 5 20 4.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 24 35 4.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 37 52 4.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27350 4a87415560f5448fae3a33f61d15610f 102 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 4.3E-13 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS26135 7af3530616aeddc3b289c39d8c8f28e2 503 Gene3D G3DSA:2.115.10.20 160 343 1.4E-16 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS26135 7af3530616aeddc3b289c39d8c8f28e2 503 SUPERFAMILY SSF75005 131 250 1.31E-15 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS26135 7af3530616aeddc3b289c39d8c8f28e2 503 Gene3D G3DSA:2.115.10.20 14 159 6.1E-8 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS02065 543adf52b462686ae371381f41048681 330 Gene3D G3DSA:1.10.3720.10 40 328 4.9E-43 T 28-03-2018 CNX65_RS02065 543adf52b462686ae371381f41048681 330 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 117 318 8.5E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02065 543adf52b462686ae371381f41048681 330 SUPERFAMILY SSF161098 86 315 3.92E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08905 73c339a4829375e45804085fd17c858e 272 Gene3D G3DSA:1.10.3720.10 2 259 4.4E-34 T 28-03-2018 CNX65_RS08905 73c339a4829375e45804085fd17c858e 272 SUPERFAMILY SSF161098 4 272 3.18E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08905 73c339a4829375e45804085fd17c858e 272 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 257 7.4E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS22345 658145f328276f232d03b9c25735ff95 218 Pfam PF04299 Putative FMN-binding domain 1 167 7.8E-38 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type CNX65_RS22345 658145f328276f232d03b9c25735ff95 218 Gene3D G3DSA:2.30.110.10 1 209 6.1E-45 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS22345 658145f328276f232d03b9c25735ff95 218 PIRSF PIRSF010372 1 209 2.3E-40 T 28-03-2018 IPR007396 Transcriptional regulator PAI 2-type CNX65_RS22345 658145f328276f232d03b9c25735ff95 218 SUPERFAMILY SSF50475 11 192 1.53E-27 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS05310 2e95c6b65253832ce197c7c490c4e04a 209 Gene3D G3DSA:3.30.420.10 2 179 6.6E-30 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS05310 2e95c6b65253832ce197c7c490c4e04a 209 Pfam PF00929 Exonuclease 6 169 8.5E-33 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS05310 2e95c6b65253832ce197c7c490c4e04a 209 Hamap MF_00045 Oligoribonuclease [orn]. 1 180 38.163 T 28-03-2018 IPR022894 Oligoribonuclease GO:0000175 CNX65_RS05310 2e95c6b65253832ce197c7c490c4e04a 209 SMART SM00479 4 179 1.6E-30 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS05310 2e95c6b65253832ce197c7c490c4e04a 209 SUPERFAMILY SSF53098 4 178 4.42E-43 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS13125 d11cbfe25ad9ab06dc03bbfb61df55ba 145 SUPERFAMILY SSF160424 9 143 1.18E-26 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS27880 b7c288d178c4db1f7127273d923fee03 218 PIRSF PIRSF028451 2 213 1.4E-30 T 28-03-2018 IPR015996 Uncharacterised conserved protein UCP028451 CNX65_RS27880 b7c288d178c4db1f7127273d923fee03 218 TIGRFAM TIGR02453 TIGR02453: TIGR02453 family protein 7 206 2.8E-35 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 CNX65_RS27880 b7c288d178c4db1f7127273d923fee03 218 Pfam PF09365 Conserved hypothetical protein (DUF2461) 10 204 1.4E-46 T 28-03-2018 IPR012808 Conserved hypothetical protein CHP02453 CNX65_RS03430 484ed2dcdeb341d31a67b5de566bc531 353 Gene3D G3DSA:3.30.470.20 220 328 3.4E-10 T 28-03-2018 CNX65_RS03430 484ed2dcdeb341d31a67b5de566bc531 353 SUPERFAMILY SSF56059 224 327 3.81E-9 T 28-03-2018 CNX65_RS32075 bf830cb380c5fdeff72402a91da869f7 306 Pfam PF16751 Anti-sigma-D factor RsdA to sigma factor binding region 34 79 2.0E-10 T 28-03-2018 IPR031928 Anti-sigma-D factor RsdA, sigma factor binding region CNX65_RS23425 104650bba8aa52f6b220e401f30583aa 148 Gene3D G3DSA:1.10.10.10 35 136 4.0E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS23425 104650bba8aa52f6b220e401f30583aa 148 Pfam PF01638 HxlR-like helix-turn-helix 38 124 9.9E-27 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS23425 104650bba8aa52f6b220e401f30583aa 148 SUPERFAMILY SSF46785 27 136 5.66E-33 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27715 99230ca9e009a9aef8167dae607a2260 201 Gene3D G3DSA:3.40.109.10 8 200 8.4E-36 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS27715 99230ca9e009a9aef8167dae607a2260 201 SUPERFAMILY SSF55469 18 200 5.63E-42 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS27715 99230ca9e009a9aef8167dae607a2260 201 Pfam PF00881 Nitroreductase family 21 179 1.7E-15 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS06490 1c604e9792312605f9ebde7a218d08d7 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 1.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS06490 1c604e9792312605f9ebde7a218d08d7 201 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 1.2E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS06490 1c604e9792312605f9ebde7a218d08d7 201 SUPERFAMILY SSF46689 7 79 1.2E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS06490 1c604e9792312605f9ebde7a218d08d7 201 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 63 1.2E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS06490 1c604e9792312605f9ebde7a218d08d7 201 Gene3D G3DSA:1.10.357.10 1 199 3.8E-29 T 28-03-2018 CNX65_RS27875 422bca8dc89c96c466a31ec7d6ee2bce 119 Pfam PF04892 VanZ like family 33 102 5.1E-7 T 28-03-2018 IPR006976 VanZ-like CNX65_RS23950 0c3d9fc7fc427a34e355d554e4dcb1e8 261 Pfam PF01261 Xylose isomerase-like TIM barrel 24 213 6.9E-25 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS23950 0c3d9fc7fc427a34e355d554e4dcb1e8 261 Gene3D G3DSA:3.20.20.150 1 257 5.6E-43 T 28-03-2018 CNX65_RS23950 0c3d9fc7fc427a34e355d554e4dcb1e8 261 SUPERFAMILY SSF51658 6 255 7.73E-40 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS28450 a2c22325c7c30ef44eb4b34d96fca26b 268 Pfam PF01553 Acyltransferase 40 158 5.5E-16 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS28450 a2c22325c7c30ef44eb4b34d96fca26b 268 Gene3D G3DSA:3.40.1130.10 14 245 1.1E-30 T 28-03-2018 CNX65_RS28450 a2c22325c7c30ef44eb4b34d96fca26b 268 SMART SM00563 43 162 4.6E-27 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS28450 a2c22325c7c30ef44eb4b34d96fca26b 268 SUPERFAMILY SSF69593 39 232 1.83E-26 T 28-03-2018 CNX65_RS28255 8e1f9569e54f89abdfe1f2a5a137695e 487 Pfam PF01098 Cell cycle protein 36 389 7.4E-106 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CNX65_RS28255 8e1f9569e54f89abdfe1f2a5a137695e 487 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 37 388 5.8E-107 T 28-03-2018 IPR013437 Cell division protein FtsW GO:0009252|GO:0016021|GO:0051301 CNX65_RS28255 8e1f9569e54f89abdfe1f2a5a137695e 487 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 347 371 - T 28-03-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0007049|GO:0016021 CNX65_RS28365 37a19cd4e7a122866e93968361d78f0f 243 SUPERFAMILY SSF53335 17 193 2.74E-27 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS28365 37a19cd4e7a122866e93968361d78f0f 243 Gene3D G3DSA:3.40.50.150 2 243 6.4E-32 T 28-03-2018 CNX65_RS28365 37a19cd4e7a122866e93968361d78f0f 243 Pfam PF13489 Methyltransferase domain 16 187 3.2E-15 T 28-03-2018 CNX65_RS01170 3d4c7e16e82d171876fad915c81a4dae 279 Gene3D G3DSA:3.90.79.10 36 259 2.0E-28 T 28-03-2018 CNX65_RS01170 3d4c7e16e82d171876fad915c81a4dae 279 SUPERFAMILY SSF55811 169 229 5.59E-16 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS01170 3d4c7e16e82d171876fad915c81a4dae 279 SUPERFAMILY SSF55811 29 126 5.59E-16 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS20080 d36468a9bb6875b48302b1e298de5f18 213 SUPERFAMILY SSF49329 87 209 1.57E-11 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CNX65_RS20080 d36468a9bb6875b48302b1e298de5f18 213 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 83 207 6.6E-11 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CNX65_RS20080 d36468a9bb6875b48302b1e298de5f18 213 Gene3D G3DSA:2.60.40.200 61 211 4.0E-14 T 28-03-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 CNX65_RS27595 eb937b9772d5339cf5b1868829330aa0 171 Gene3D G3DSA:1.20.120.450 4 171 5.3E-25 T 28-03-2018 CNX65_RS27595 eb937b9772d5339cf5b1868829330aa0 171 SUPERFAMILY SSF109854 6 166 1.68E-32 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS27595 eb937b9772d5339cf5b1868829330aa0 171 Pfam PF04978 Protein of unknown function (DUF664) 22 167 3.1E-35 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CNX65_RS03835 fad4d2a1331e51e79814b146a1dc3c03 286 Pfam PF00809 Pterin binding enzyme 16 257 3.4E-66 T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS03835 fad4d2a1331e51e79814b146a1dc3c03 286 SUPERFAMILY SSF51717 5 276 1.01E-76 T 28-03-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS03835 fad4d2a1331e51e79814b146a1dc3c03 286 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 15 30 - T 28-03-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 CNX65_RS03835 fad4d2a1331e51e79814b146a1dc3c03 286 Gene3D G3DSA:3.20.20.20 2 286 5.7E-84 T 28-03-2018 CNX65_RS03835 fad4d2a1331e51e79814b146a1dc3c03 286 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 15 271 5.1E-81 T 28-03-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 CNX65_RS00820 1c99daff8dd4a72f49323b44e7fa7f44 404 Pfam PF00145 C-5 cytosine-specific DNA methylase 6 365 7.6E-41 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS00820 1c99daff8dd4a72f49323b44e7fa7f44 404 TIGRFAM TIGR00675 dcm: DNA (cytosine-5-)-methyltransferase 8 362 2.4E-32 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CNX65_RS00820 1c99daff8dd4a72f49323b44e7fa7f44 404 SUPERFAMILY SSF53335 6 368 3.23E-60 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS00820 1c99daff8dd4a72f49323b44e7fa7f44 404 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 173 186 2.5E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CNX65_RS00820 1c99daff8dd4a72f49323b44e7fa7f44 404 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 7 23 2.5E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CNX65_RS00820 1c99daff8dd4a72f49323b44e7fa7f44 404 PRINTS PR00105 Cytosine-specific DNA methyltransferase signature 127 141 2.5E-15 T 28-03-2018 IPR001525 C-5 cytosine methyltransferase GO:0008168 KEGG: 00270+2.1.1.37 CNX65_RS00820 1c99daff8dd4a72f49323b44e7fa7f44 404 Gene3D G3DSA:3.40.50.150 5 239 2.2E-39 T 28-03-2018 CNX65_RS01115 2f4e9b813fe7ebc47dfe2cd6ff94a219 97 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 74 17.668 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS01115 2f4e9b813fe7ebc47dfe2cd6ff94a219 97 Pfam PF02467 Transcription factor WhiB 7 69 9.2E-22 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS04235 f175010783a91928307f7d2ffe12e6ad 319 Pfam PF04228 Putative neutral zinc metallopeptidase 117 310 3.5E-16 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CNX65_RS33695 87ed6d9a19434bfb41f46d4ecc177726 1302 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 1184 1267 3.0E-9 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CNX65_RS33695 87ed6d9a19434bfb41f46d4ecc177726 1302 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 901 1067 2.3E-45 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS33695 87ed6d9a19434bfb41f46d4ecc177726 1302 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 902 1066 2.2E-39 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS13910 1ee797c7e8c9810823d1cde7b3a595b8 274 SUPERFAMILY SSF55729 97 237 2.48E-5 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS13910 1ee797c7e8c9810823d1cde7b3a595b8 274 Gene3D G3DSA:3.40.630.30 113 271 3.3E-6 T 28-03-2018 CNX65_RS32760 1f0d49c91e7e0c16343781fc5d6ce4a8 278 Gene3D G3DSA:3.20.20.105 15 233 1.1E-6 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CNX65_RS16565 d1d8321a597609f6578cc3381315583a 545 Gene3D G3DSA:2.60.120.200 344 542 4.4E-47 T 28-03-2018 CNX65_RS16565 d1d8321a597609f6578cc3381315583a 545 SUPERFAMILY SSF49899 346 535 1.58E-27 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS16565 d1d8321a597609f6578cc3381315583a 545 SUPERFAMILY SSF75005 49 336 8.57E-62 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16565 d1d8321a597609f6578cc3381315583a 545 Gene3D G3DSA:2.115.10.20 42 332 2.4E-45 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS16565 d1d8321a597609f6578cc3381315583a 545 Pfam PF04616 Glycosyl hydrolases family 43 49 315 1.6E-36 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS10245 0e6170fdabbefc7b2cdbdd899d3c5781 316 SMART SM00943 7 198 1.5E-41 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS10245 0e6170fdabbefc7b2cdbdd899d3c5781 316 SUPERFAMILY SSF56747 2 202 1.37E-29 T 28-03-2018 CNX65_RS10245 0e6170fdabbefc7b2cdbdd899d3c5781 316 Pfam PF09250 Bifunctional DNA primase/polymerase, N-terminal 7 197 7.5E-41 T 28-03-2018 IPR015330 DNA primase/polymerase, bifunctional, N-terminal CNX65_RS05545 9dae143836c1ab72ea0b7ff49c731888 189 SUPERFAMILY SSF56112 9 181 2.65E-12 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS05545 9dae143836c1ab72ea0b7ff49c731888 189 Gene3D G3DSA:3.90.1200.10 113 185 0.0019 T 28-03-2018 CNX65_RS28640 f0bb8733eb82bb3efc0d494f41af07ff 146 SUPERFAMILY SSF47240 3 142 5.27E-37 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS28640 f0bb8733eb82bb3efc0d494f41af07ff 146 Pfam PF14530 Domain of unknown function (DUF4439) 9 146 2.3E-42 T 28-03-2018 IPR029447 Domain of unknown function DUF4439 CNX65_RS28640 f0bb8733eb82bb3efc0d494f41af07ff 146 Gene3D G3DSA:1.20.1260.10 1 134 3.1E-12 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS30390 1b4a776c02ab56769ee188a3cb4171c7 343 SUPERFAMILY SSF140931 85 260 2.75E-13 T 28-03-2018 IPR003812 Fido domain CNX65_RS30390 1b4a776c02ab56769ee188a3cb4171c7 343 Gene3D G3DSA:1.10.3290.10 11 270 6.9E-18 T 28-03-2018 IPR003812 Fido domain CNX65_RS11405 750a052b25f9cd7cc49b5533ef1eab98 261 Pfam PF00227 Proteasome subunit 25 191 1.9E-31 T 28-03-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-446652|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8941858|Reactome: R-HSA-8951664|Reactome: R-HSA-983168 CNX65_RS11405 750a052b25f9cd7cc49b5533ef1eab98 261 TIGRFAM TIGR03691 20S_bact_alpha: proteasome, alpha subunit 2 233 1.1E-109 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CNX65_RS11405 750a052b25f9cd7cc49b5533ef1eab98 261 Hamap MF_00289_B Proteasome subunit alpha [prcA]. 1 236 49.269 T 28-03-2018 IPR022296 Proteasome, alpha subunit, bacterial GO:0004298|GO:0019773|GO:0051603 CNX65_RS11405 750a052b25f9cd7cc49b5533ef1eab98 261 Gene3D G3DSA:3.60.20.10 8 238 2.1E-46 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS11405 750a052b25f9cd7cc49b5533ef1eab98 261 SUPERFAMILY SSF56235 10 233 1.47E-44 T 28-03-2018 IPR029055 Nucleophile aminohydrolases, N-terminal CNX65_RS16065 838de84163283324a664ce898fcfcb79 743 Pfam PF03176 MMPL family 45 367 2.0E-61 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS16065 838de84163283324a664ce898fcfcb79 743 Pfam PF03176 MMPL family 429 690 1.2E-35 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS16065 838de84163283324a664ce898fcfcb79 743 SUPERFAMILY SSF82866 452 686 2.35E-27 T 28-03-2018 CNX65_RS16065 838de84163283324a664ce898fcfcb79 743 Gene3D G3DSA:1.20.1640.10 114 335 3.4E-29 T 28-03-2018 CNX65_RS16065 838de84163283324a664ce898fcfcb79 743 Gene3D G3DSA:1.20.1640.10 448 683 8.4E-30 T 28-03-2018 CNX65_RS16065 838de84163283324a664ce898fcfcb79 743 SUPERFAMILY SSF82866 125 335 1.7E-29 T 28-03-2018 CNX65_RS00685 66b086064d2d8015f2d5b3940f6dc093 399 TIGRFAM TIGR01976 am_tr_V_VC1184: cysteine desulfurase family protein 3 395 3.2E-122 T 28-03-2018 IPR011340 Cysteine desulfurase-related CNX65_RS00685 66b086064d2d8015f2d5b3940f6dc093 399 Gene3D G3DSA:3.40.640.10 28 263 4.5E-38 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS00685 66b086064d2d8015f2d5b3940f6dc093 399 Gene3D G3DSA:3.90.1150.10 264 398 1.2E-18 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS00685 66b086064d2d8015f2d5b3940f6dc093 399 SUPERFAMILY SSF53383 3 398 1.14E-66 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS00685 66b086064d2d8015f2d5b3940f6dc093 399 Pfam PF00266 Aminotransferase class-V 21 391 7.2E-40 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS22845 cdf19ac1de2383162b79de272e3344a7 392 SUPERFAMILY SSF55729 180 344 8.16E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS22845 cdf19ac1de2383162b79de272e3344a7 392 Gene3D G3DSA:3.40.630.30 161 378 9.9E-24 T 28-03-2018 CNX65_RS22845 cdf19ac1de2383162b79de272e3344a7 392 Pfam PF04339 Peptidogalycan biosysnthesis/recognition 120 344 6.8E-13 T 28-03-2018 IPR007434 Peptidogalycan biosysnthesis/recognition CNX65_RS22845 cdf19ac1de2383162b79de272e3344a7 392 Gene3D G3DSA:3.40.630.30 3 160 0.0016 T 28-03-2018 CNX65_RS08975 7378589bff56f039591169288f38b215 194 Pfam PF09970 Nucleotidyl transferase of unknown function (DUF2204) 10 165 2.3E-5 T 28-03-2018 IPR018700 Protein of unknown function DUF2204 CNX65_RS08975 7378589bff56f039591169288f38b215 194 SUPERFAMILY SSF81301 5 139 1.21E-24 T 28-03-2018 CNX65_RS08975 7378589bff56f039591169288f38b215 194 Gene3D G3DSA:3.30.70.790 12 70 2.0E-4 T 28-03-2018 CNX65_RS34930 d20345b2a4a2b8fb40a9ab74efee3ea7 710 SUPERFAMILY SSF82866 453 671 7.59E-28 T 28-03-2018 CNX65_RS34930 d20345b2a4a2b8fb40a9ab74efee3ea7 710 SUPERFAMILY SSF82866 125 320 4.97E-32 T 28-03-2018 CNX65_RS34930 d20345b2a4a2b8fb40a9ab74efee3ea7 710 Pfam PF03176 MMPL family 78 351 9.8E-46 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS34930 d20345b2a4a2b8fb40a9ab74efee3ea7 710 Pfam PF03176 MMPL family 441 672 4.3E-31 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS34930 d20345b2a4a2b8fb40a9ab74efee3ea7 710 Gene3D G3DSA:1.20.1640.10 456 668 6.2E-29 T 28-03-2018 CNX65_RS34930 d20345b2a4a2b8fb40a9ab74efee3ea7 710 Gene3D G3DSA:1.20.1640.10 106 321 1.8E-33 T 28-03-2018 CNX65_RS00680 b49b44dbdd445a0caa8171afb792d2ab 182 Pfam PF10759 Protein of unknown function (DUF2587) 34 181 6.2E-79 T 28-03-2018 IPR019695 Bacterial proteasome activator GO:0061136 CNX65_RS23195 f36d3a5c0812347efaf71609db4b8494 444 Gene3D G3DSA:1.20.1250.20 33 237 7.4E-30 T 28-03-2018 CNX65_RS23195 f36d3a5c0812347efaf71609db4b8494 444 Gene3D G3DSA:1.20.1250.20 242 427 7.2E-15 T 28-03-2018 CNX65_RS23195 f36d3a5c0812347efaf71609db4b8494 444 SUPERFAMILY SSF103473 49 421 5.36E-46 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS23195 f36d3a5c0812347efaf71609db4b8494 444 Pfam PF07690 Major Facilitator Superfamily 55 258 2.2E-18 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS24220 1903ef5c4484a2d6cf1bda8ad676ce04 259 Gene3D G3DSA:3.40.50.300 1 230 1.1E-66 T 28-03-2018 CNX65_RS24220 1903ef5c4484a2d6cf1bda8ad676ce04 259 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS24220 1903ef5c4484a2d6cf1bda8ad676ce04 259 SMART SM00382 29 215 1.2E-21 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS24220 1903ef5c4484a2d6cf1bda8ad676ce04 259 SUPERFAMILY SSF52540 4 227 3.73E-65 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24220 1903ef5c4484a2d6cf1bda8ad676ce04 259 Pfam PF00005 ABC transporter 21 169 3.4E-33 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS22385 b05b0c40af245472d6a99f5136d91d38 305 SUPERFAMILY SSF54211 11 166 2.66E-17 T 28-03-2018 IPR020568 Ribosomal protein S5 domain 2-type fold CNX65_RS22385 b05b0c40af245472d6a99f5136d91d38 305 Pfam PF00288 GHMP kinases N terminal domain 85 116 2.0E-7 T 28-03-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 CNX65_RS22385 b05b0c40af245472d6a99f5136d91d38 305 Gene3D G3DSA:3.30.230.10 25 155 3.7E-13 T 28-03-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup CNX65_RS22385 b05b0c40af245472d6a99f5136d91d38 305 Gene3D G3DSA:3.30.70.890 158 278 0.0016 T 28-03-2018 IPR013750 GHMP kinase, C-terminal domain CNX65_RS22385 b05b0c40af245472d6a99f5136d91d38 305 PIRSF PIRSF033887 2 290 2.4E-83 T 28-03-2018 IPR012363 Propanediol utilisation/coumermycin biosynthesis, PduX-related KEGG: 00040+2.7.1.17|KEGG: 00860+2.7.1.177|MetaCyc: PWY-5443 CNX65_RS04755 31722c89e75643eeca15c6cb8fd42277 241 SUPERFAMILY SSF55073 10 139 1.11E-7 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS04755 31722c89e75643eeca15c6cb8fd42277 241 Gene3D G3DSA:3.30.70.1230 4 178 1.6E-5 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS26320 a980915a8e5e92d762c5430185350c69 493 SUPERFAMILY SSF55931 38 459 2.75E-56 T 28-03-2018 CNX65_RS26320 a980915a8e5e92d762c5430185350c69 493 PIRSF PIRSF012666 1 492 6.7E-219 T 28-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 CNX65_RS13850 888c58c090895e31ec2ef2f84fa3ca53 350 Pfam PF01032 FecCD transport family 22 342 3.5E-88 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS13850 888c58c090895e31ec2ef2f84fa3ca53 350 SUPERFAMILY SSF81345 12 343 6.02E-75 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS13850 888c58c090895e31ec2ef2f84fa3ca53 350 Gene3D G3DSA:1.10.3470.10 10 345 8.6E-66 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 Gene3D G3DSA:1.10.10.10 131 205 7.1E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 Pfam PF00072 Response regulator receiver domain 4 112 2.3E-25 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 160 187 - T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 SUPERFAMILY SSF46894 133 206 4.76E-20 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 176 188 1.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 146 160 1.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 160 176 1.8E-9 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 200 2.0E-15 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 SMART SM00448 2 112 9.1E-28 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 Gene3D G3DSA:3.40.50.2300 1 130 3.8E-33 T 28-03-2018 CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 SUPERFAMILY SSF52172 3 126 4.27E-29 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS16415 778d69ba96f9438d706199d22082e31d 208 SMART SM00421 143 200 1.6E-22 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS32735 e2d2b3c733f68a495c71d5ac370b1b5e 238 Gene3D G3DSA:1.20.120.160 17 237 0.075 T 28-03-2018 CNX65_RS28665 2e2363c7c179a5854cf73418460c4a41 266 Gene3D G3DSA:3.40.1000.10 87 263 5.8E-4 T 28-03-2018 CNX65_RS07320 915674c72ce228c797e8e93b714ded83 267 PIRSF PIRSF006648 2 266 9.4E-68 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS07320 915674c72ce228c797e8e93b714ded83 267 Pfam PF01061 ABC-2 type transporter 13 219 7.7E-24 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS33510 3eff2a0ad084694be6269a666f8d370c 108 Gene3D G3DSA:1.20.1270.70 59 106 3.4E-4 T 28-03-2018 CNX65_RS10715 c46af82743a74271726fca6671b9291a 536 Pfam PF13556 PucR C-terminal helix-turn-helix domain 473 530 5.4E-13 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS10715 c46af82743a74271726fca6671b9291a 536 Pfam PF07905 Purine catabolism regulatory protein-like family 8 129 5.4E-36 T 28-03-2018 IPR012914 Purine catabolism PurC-like domain CNX65_RS24135 5125101a4dc5669e2d5feefcbfc0cc75 267 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 90 258 2.7E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS24135 5125101a4dc5669e2d5feefcbfc0cc75 267 Gene3D G3DSA:1.10.3720.10 24 267 9.1E-22 T 28-03-2018 CNX65_RS24135 5125101a4dc5669e2d5feefcbfc0cc75 267 SUPERFAMILY SSF161098 69 250 9.42E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08965 253c414e8e2e4a6a9abaab448a897ba7 197 Pfam PF03358 NADPH-dependent FMN reductase 4 152 1.0E-13 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CNX65_RS08965 253c414e8e2e4a6a9abaab448a897ba7 197 SUPERFAMILY SSF52218 3 184 1.86E-23 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS08965 253c414e8e2e4a6a9abaab448a897ba7 197 Gene3D G3DSA:3.40.50.360 1 194 2.4E-22 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS19510 4edd4bf4ab26ca6b0df031f3c4562040 207 SUPERFAMILY SSF48498 91 193 3.67E-17 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS19510 4edd4bf4ab26ca6b0df031f3c4562040 207 SUPERFAMILY SSF46689 17 85 5.64E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS19510 4edd4bf4ab26ca6b0df031f3c4562040 207 Gene3D G3DSA:1.10.357.10 68 204 7.6E-18 T 28-03-2018 CNX65_RS19510 4edd4bf4ab26ca6b0df031f3c4562040 207 Gene3D G3DSA:1.10.10.60 2 67 9.6E-10 T 28-03-2018 CNX65_RS14240 b596420d91369a496a1766ce99ec3aca 264 SUPERFAMILY SSF53254 43 221 8.12E-25 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS14240 b596420d91369a496a1766ce99ec3aca 264 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 44 203 1.1E-17 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS14240 b596420d91369a496a1766ce99ec3aca 264 Gene3D G3DSA:3.40.50.1240 34 220 7.9E-27 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS32645 d2ae4e572975bda09b03b98fd3f625cf 291 Gene3D G3DSA:3.40.630.30 119 285 4.6E-5 T 28-03-2018 CNX65_RS20095 f2c9469801d9c6b137158ee79ec1d526 221 SUPERFAMILY SSF46894 114 199 7.66E-23 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS20095 f2c9469801d9c6b137158ee79ec1d526 221 SMART SM00862 126 199 1.3E-23 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS20095 f2c9469801d9c6b137158ee79ec1d526 221 Pfam PF00486 Transcriptional regulatory protein, C terminal 127 198 1.7E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS20095 f2c9469801d9c6b137158ee79ec1d526 221 Gene3D G3DSA:1.10.10.10 111 205 4.8E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18115 a7b2d7b4c9bc8abe33c908920a643397 67 SUPERFAMILY SSF160582 3 64 4.58E-27 T 28-03-2018 CNX65_RS18115 a7b2d7b4c9bc8abe33c908920a643397 67 Pfam PF03621 MbtH-like protein 3 49 1.2E-20 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS18115 a7b2d7b4c9bc8abe33c908920a643397 67 SMART SM00923 1 49 1.1E-19 T 28-03-2018 IPR005153 MbtH-like protein CNX65_RS18115 a7b2d7b4c9bc8abe33c908920a643397 67 Gene3D G3DSA:3.90.820.10 1 64 1.1E-30 T 28-03-2018 CNX65_RS18550 547a781eb25d06ef6847f1141703453a 164 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 152 1.3E-19 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 CNX65_RS18765 a820b5ee0650e7f1d0e0346dc4e44fd6 208 Gene3D G3DSA:1.20.144.10 4 204 6.6E-6 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS18765 a820b5ee0650e7f1d0e0346dc4e44fd6 208 SUPERFAMILY SSF48317 71 199 3.27E-7 T 28-03-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase CNX65_RS05135 c67feb8fa46de18ea90fb13bd8e7fae9 175 Gene3D G3DSA:2.60.40.1240 32 167 1.2E-6 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CNX65_RS18890 8b6733852353825c82ca99c76861a4e5 137 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 5 131 2.6E-10 T 28-03-2018 IPR028973 PhnB-like CNX65_RS18890 8b6733852353825c82ca99c76861a4e5 137 SUPERFAMILY SSF54593 3 132 2.09E-31 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS18890 8b6733852353825c82ca99c76861a4e5 137 Gene3D G3DSA:3.10.180.10 1 137 8.3E-24 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS30410 f38e807776fa4ca3ca80f4b3616056bb 344 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 71 303 4.5E-38 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CNX65_RS30410 f38e807776fa4ca3ca80f4b3616056bb 344 Gene3D G3DSA:1.10.40.50 248 315 4.6E-18 T 28-03-2018 CNX65_RS30410 f38e807776fa4ca3ca80f4b3616056bb 344 Pfam PF03193 RsgA GTPase 72 247 4.0E-40 T 28-03-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 CNX65_RS30410 f38e807776fa4ca3ca80f4b3616056bb 344 SUPERFAMILY SSF52540 88 309 5.46E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS30410 f38e807776fa4ca3ca80f4b3616056bb 344 Hamap MF_01820 Putative ribosome biogenesis GTPase RsgA [rsgA]. 24 311 29.874 T 28-03-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 CNX65_RS30410 f38e807776fa4ca3ca80f4b3616056bb 344 SMART SM00382 179 307 0.0045 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS30410 f38e807776fa4ca3ca80f4b3616056bb 344 Gene3D G3DSA:3.40.50.300 87 247 7.9E-27 T 28-03-2018 CNX65_RS22550 45ed4d6c1fbf20ade798b661607ff85b 80 Pfam PF00550 Phosphopantetheine attachment site 2 68 3.0E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22550 45ed4d6c1fbf20ade798b661607ff85b 80 SUPERFAMILY SSF47336 2 77 2.75E-13 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS22550 45ed4d6c1fbf20ade798b661607ff85b 80 Gene3D G3DSA:1.10.1200.10 1 77 2.3E-12 T 28-03-2018 CNX65_RS22095 fb564c4bb7306d0a95778d25dc391f27 272 Pfam PF01475 Ferric uptake regulator family 139 255 8.2E-15 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CNX65_RS22095 fb564c4bb7306d0a95778d25dc391f27 272 SUPERFAMILY SSF46785 139 262 6.65E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22095 fb564c4bb7306d0a95778d25dc391f27 272 Gene3D G3DSA:1.10.10.10 136 217 2.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS30465 4ccbc64f714f5b603a779b1f6ddb2eb1 560 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 454 2.9E-63 T 28-03-2018 IPR000914 Solute-binding protein family 5 domain CNX65_RS30465 4ccbc64f714f5b603a779b1f6ddb2eb1 560 PIRSF PIRSF002741 9 548 4.6E-60 T 28-03-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 CNX65_RS30465 4ccbc64f714f5b603a779b1f6ddb2eb1 560 Gene3D G3DSA:3.90.76.10 59 153 1.1E-18 T 28-03-2018 CNX65_RS30465 4ccbc64f714f5b603a779b1f6ddb2eb1 560 Gene3D G3DSA:3.40.190.10 154 293 9.9E-26 T 28-03-2018 CNX65_RS30465 4ccbc64f714f5b603a779b1f6ddb2eb1 560 SUPERFAMILY SSF53850 37 543 1.3E-87 T 28-03-2018 CNX65_RS30465 4ccbc64f714f5b603a779b1f6ddb2eb1 560 Gene3D G3DSA:3.10.105.10 294 514 8.6E-38 T 28-03-2018 CNX65_RS07290 b3b68f1d7af1d4cf403a3e77e11f162f 274 SMART SM00079 37 253 0.0016 T 28-03-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 CNX65_RS07290 b3b68f1d7af1d4cf403a3e77e11f162f 274 Gene3D G3DSA:3.40.190.10 135 224 1.2E-21 T 28-03-2018 CNX65_RS07290 b3b68f1d7af1d4cf403a3e77e11f162f 274 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 38 256 1.3E-49 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS07290 b3b68f1d7af1d4cf403a3e77e11f162f 274 Gene3D G3DSA:3.40.190.10 31 134 1.5E-24 T 28-03-2018 CNX65_RS07290 b3b68f1d7af1d4cf403a3e77e11f162f 274 SUPERFAMILY SSF53850 10 255 3.08E-55 T 28-03-2018 CNX65_RS07290 b3b68f1d7af1d4cf403a3e77e11f162f 274 SMART SM00062 37 262 7.1E-63 T 28-03-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF CNX65_RS00085 5f84e583518c2ebac2a7588ae3b9082d 88 Hamap MF_00631 Cell division protein CrgA [crgA]. 1 88 23.296 T 28-03-2018 IPR009619 Cell division protein CrgA CNX65_RS00085 5f84e583518c2ebac2a7588ae3b9082d 88 Pfam PF06781 Cell division protein CrgA 1 88 4.2E-38 T 28-03-2018 IPR009619 Cell division protein CrgA CNX65_RS12065 51d2576e93310b020c489d6249f1504a 382 Gene3D G3DSA:3.40.50.2300 1 230 1.1E-24 T 28-03-2018 CNX65_RS12065 51d2576e93310b020c489d6249f1504a 382 SUPERFAMILY SSF52172 1 140 1.05E-23 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS12065 51d2576e93310b020c489d6249f1504a 382 Pfam PF00072 Response regulator receiver domain 6 120 6.3E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12065 51d2576e93310b020c489d6249f1504a 382 SMART SM00448 4 120 8.0E-15 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS07650 bcd52bb7d205b9287197412f66a6d652 300 Gene3D G3DSA:3.90.25.10 145 298 1.1E-14 T 28-03-2018 CNX65_RS07650 bcd52bb7d205b9287197412f66a6d652 300 Gene3D G3DSA:3.40.50.720 2 144 7.0E-9 T 28-03-2018 CNX65_RS07650 bcd52bb7d205b9287197412f66a6d652 300 SUPERFAMILY SSF51735 8 293 6.12E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07650 bcd52bb7d205b9287197412f66a6d652 300 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 199 7.2E-11 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS15120 a6e9d99f0d5cbedda3b8352c2ef47aa4 371 Gene3D G3DSA:3.30.420.10 94 276 2.7E-22 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS15120 a6e9d99f0d5cbedda3b8352c2ef47aa4 371 SUPERFAMILY SSF53098 99 255 1.14E-24 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS15120 a6e9d99f0d5cbedda3b8352c2ef47aa4 371 SMART SM00479 98 260 2.2E-12 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS15120 a6e9d99f0d5cbedda3b8352c2ef47aa4 371 Pfam PF00929 Exonuclease 100 248 8.0E-10 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS31250 ad8c81e4aac66b611e11435ea1e968f1 141 Pfam PF07681 DoxX 12 94 6.9E-19 T 28-03-2018 IPR032808 DoxX family CNX65_RS32665 d898885fe552f8cd402ce9425cb3a09b 466 Gene3D G3DSA:1.10.260.40 4 88 0.0048 T 28-03-2018 CNX65_RS32665 d898885fe552f8cd402ce9425cb3a09b 466 SUPERFAMILY SSF48452 215 421 8.35E-7 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS32665 d898885fe552f8cd402ce9425cb3a09b 466 Gene3D G3DSA:1.25.40.10 327 457 2.5E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS32665 d898885fe552f8cd402ce9425cb3a09b 466 Gene3D G3DSA:1.25.40.10 100 326 0.0071 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS24295 0cefa71c82523e4e9358da7b87fffa5c 396 Gene3D G3DSA:1.20.1250.20 12 204 7.7E-22 T 28-03-2018 CNX65_RS24295 0cefa71c82523e4e9358da7b87fffa5c 396 Pfam PF07690 Major Facilitator Superfamily 23 355 2.7E-19 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS24295 0cefa71c82523e4e9358da7b87fffa5c 396 Gene3D G3DSA:1.20.1250.20 208 392 1.1E-12 T 28-03-2018 CNX65_RS24295 0cefa71c82523e4e9358da7b87fffa5c 396 SUPERFAMILY SSF103473 19 390 2.62E-37 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 ProSitePatterns PS00893 Nudix box signature. 441 462 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 SUPERFAMILY SSF103473 38 403 8.63E-29 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 Gene3D G3DSA:1.20.1250.20 38 226 1.1E-12 T 28-03-2018 CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 Pfam PF00293 NUDIX domain 407 488 2.6E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 PRINTS PR00502 NUDIX hydrolase family signature 436 450 1.0E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 PRINTS PR00502 NUDIX hydrolase family signature 450 465 1.0E-6 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 Gene3D G3DSA:3.90.79.10 400 535 9.8E-24 T 28-03-2018 CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 SUPERFAMILY SSF55811 389 529 3.93E-25 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS17465 3279ff87fe382f245f48ecdb9e64a496 542 Gene3D G3DSA:1.20.1250.20 227 399 1.3E-6 T 28-03-2018 CNX65_RS02860 57ddf7cfc6f771ec0cf8470dea9ec96e 176 Pfam PF09933 Predicted small integral membrane protein (DUF2165) 11 159 4.4E-51 T 28-03-2018 IPR018681 Protein of unknown function DUF2165, transmembrane CNX65_RS04895 31df20ee246aa5eeffce9824ead7800b 106 Pfam PF05336 L-rhamnose mutarotase 3 105 2.1E-27 T 28-03-2018 IPR008000 Rhamnose/fucose mutarotase GO:0005737|GO:0016857 CNX65_RS04895 31df20ee246aa5eeffce9824ead7800b 106 Gene3D G3DSA:3.30.70.100 1 88 5.9E-4 T 28-03-2018 CNX65_RS04895 31df20ee246aa5eeffce9824ead7800b 106 SUPERFAMILY SSF54909 1 106 3.49E-31 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS01365 dfb2686ed66c1e6788927d2a2e140b8a 182 Pfam PF00583 Acetyltransferase (GNAT) family 61 155 7.2E-10 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS01365 dfb2686ed66c1e6788927d2a2e140b8a 182 SUPERFAMILY SSF55729 18 155 8.23E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS01365 dfb2686ed66c1e6788927d2a2e140b8a 182 Gene3D G3DSA:3.40.630.30 24 178 2.7E-15 T 28-03-2018 CNX65_RS11315 cf41f17e1d1ac3592267dbdb68c30ac2 376 Gene3D G3DSA:3.10.580.10 150 376 1.3E-4 T 28-03-2018 CNX65_RS11315 cf41f17e1d1ac3592267dbdb68c30ac2 376 PIRSF PIRSF006404 13 376 1.1E-67 T 28-03-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS CNX65_RS11315 cf41f17e1d1ac3592267dbdb68c30ac2 376 Pfam PF02163 Peptidase family M50 151 194 3.8E-7 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CNX65_RS11715 55d08c101af89d31649e30082a7ef8b2 195 SUPERFAMILY SSF46689 5 57 2.32E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS11715 55d08c101af89d31649e30082a7ef8b2 195 Gene3D G3DSA:1.10.10.60 2 67 7.9E-21 T 28-03-2018 CNX65_RS11715 55d08c101af89d31649e30082a7ef8b2 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 6.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11715 55d08c101af89d31649e30082a7ef8b2 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 6.9E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11715 55d08c101af89d31649e30082a7ef8b2 195 Gene3D G3DSA:1.10.357.10 68 195 3.3E-16 T 28-03-2018 CNX65_RS11715 55d08c101af89d31649e30082a7ef8b2 195 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 59 - T 28-03-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site CNX65_RS11715 55d08c101af89d31649e30082a7ef8b2 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 18 56 2.8E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14115 8be98ae9f47a52a65c3592016e0822f6 729 SUPERFAMILY SSF82866 462 694 4.84E-30 T 28-03-2018 CNX65_RS14115 8be98ae9f47a52a65c3592016e0822f6 729 Pfam PF03176 MMPL family 45 344 2.1E-63 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS14115 8be98ae9f47a52a65c3592016e0822f6 729 Pfam PF03176 MMPL family 442 694 8.1E-35 T 28-03-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 CNX65_RS14115 8be98ae9f47a52a65c3592016e0822f6 729 SUPERFAMILY SSF82866 133 331 1.44E-29 T 28-03-2018 CNX65_RS14115 8be98ae9f47a52a65c3592016e0822f6 729 Gene3D G3DSA:1.20.1640.10 115 344 6.3E-31 T 28-03-2018 CNX65_RS14115 8be98ae9f47a52a65c3592016e0822f6 729 Gene3D G3DSA:1.20.1640.10 472 692 1.4E-31 T 28-03-2018 CNX65_RS31135 1a216964e0c50d5f1e31ecb3d75ef3d8 119 Pfam PF12005 Protein of unknown function (DUF3499) 4 115 4.3E-47 T 28-03-2018 IPR021888 Protein of unknown function DUF3499 CNX65_RS14285 db339f730674758c1e6e1ad2da3268ae 629 Gene3D G3DSA:1.50.10.10 327 429 0.023 T 28-03-2018 CNX65_RS14285 db339f730674758c1e6e1ad2da3268ae 629 Pfam PF07944 Beta-L-arabinofuranosidase, GH127 30 550 4.8E-110 T 28-03-2018 IPR012878 Beta-L-arabinofuranosidase, GH127 KEGG: 00511+3.2.1.18|KEGG: 00600+3.2.1.18 CNX65_RS14285 db339f730674758c1e6e1ad2da3268ae 629 SUPERFAMILY SSF48208 136 375 1.81E-23 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS14285 db339f730674758c1e6e1ad2da3268ae 629 Gene3D G3DSA:1.50.10.20 30 326 3.5E-33 T 28-03-2018 CNX65_RS28660 f8819065d77ddd19056ff77173d5abfc 135 SUPERFAMILY SSF111038 4 132 4.45E-29 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CNX65_RS28660 f8819065d77ddd19056ff77173d5abfc 135 Gene3D G3DSA:2.60.120.460 1 134 2.8E-28 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CNX65_RS28660 f8819065d77ddd19056ff77173d5abfc 135 Pfam PF01894 Uncharacterised protein family UPF0047 18 130 3.9E-21 T 28-03-2018 IPR001602 Uncharacterised protein family UPF0047 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 PRINTS PR00834 HtrA/DegQ protease family signature 357 374 1.7E-45 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 PRINTS PR00834 HtrA/DegQ protease family signature 379 396 1.7E-45 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 PRINTS PR00834 HtrA/DegQ protease family signature 316 340 1.7E-45 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 PRINTS PR00834 HtrA/DegQ protease family signature 276 296 1.7E-45 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 PRINTS PR00834 HtrA/DegQ protease family signature 457 469 1.7E-45 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 PRINTS PR00834 HtrA/DegQ protease family signature 250 262 1.7E-45 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 Gene3D G3DSA:2.40.10.10 317 413 1.7E-34 T 28-03-2018 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 Pfam PF13180 PDZ domain 435 508 3.5E-12 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 Gene3D G3DSA:2.40.10.10 212 316 2.3E-28 T 28-03-2018 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 SUPERFAMILY SSF50156 440 509 2.1E-14 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 Pfam PF13365 Trypsin-like peptidase domain 241 386 1.7E-31 T 28-03-2018 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 SMART SM00228 398 499 1.9E-7 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 Gene3D G3DSA:2.30.42.10 414 511 1.0E-15 T 28-03-2018 CNX65_RS03940 44e17c4e28f88c36172bdfd275e5d411 511 SUPERFAMILY SSF50494 215 421 1.99E-53 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS15320 4e357b30ca9c438ccc62890880379310 117 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 112 1.5E-8 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS15320 4e357b30ca9c438ccc62890880379310 117 SUPERFAMILY SSF54593 3 115 1.03E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS15320 4e357b30ca9c438ccc62890880379310 117 Gene3D G3DSA:3.10.180.10 1 117 1.4E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS32200 7cdf82e2cbd4c7169423368ed67d9dab 919 Pfam PF06013 Proteins of 100 residues with WXG 174 250 4.7E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS32200 7cdf82e2cbd4c7169423368ed67d9dab 919 Gene3D G3DSA:1.10.287.850 170 263 5.4E-8 T 28-03-2018 CNX65_RS32200 7cdf82e2cbd4c7169423368ed67d9dab 919 SUPERFAMILY SSF140453 174 252 1.96E-7 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS05775 28e193e939fa659051a2198e2c7d6328 448 SUPERFAMILY SSF103473 14 434 6.8E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS05775 28e193e939fa659051a2198e2c7d6328 448 Pfam PF07690 Major Facilitator Superfamily 30 389 2.2E-30 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS05775 28e193e939fa659051a2198e2c7d6328 448 Gene3D G3DSA:1.20.1250.20 231 431 4.3E-17 T 28-03-2018 CNX65_RS05775 28e193e939fa659051a2198e2c7d6328 448 Gene3D G3DSA:1.20.1250.20 11 213 7.0E-19 T 28-03-2018 CNX65_RS34580 67f076b096b80a34bc387a03c7730992 92 Pfam PF11755 Protein of unknown function (DUF3311) 20 72 2.2E-14 T 28-03-2018 IPR021741 Protein of unknown function DUF3311 CNX65_RS27665 e2328d11c3f45747f53b65a2c13a29fb 93 Pfam PF02583 Metal-sensitive transcriptional repressor 7 88 8.4E-32 T 28-03-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 CNX65_RS33980 84ca9653c5179c45bed670d6eb828e9b 262 ProSitePatterns PS00953 Glycosyl hydrolases family 25 active sites signature. 66 99 - T 28-03-2018 IPR008270 Glycoside hydrolase, family 25, active site GO:0003796|GO:0009253|GO:0016998 CNX65_RS33980 84ca9653c5179c45bed670d6eb828e9b 262 SUPERFAMILY SSF51445 59 260 1.01E-63 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS33980 84ca9653c5179c45bed670d6eb828e9b 262 Pfam PF01183 Glycosyl hydrolases family 25 65 244 1.2E-48 T 28-03-2018 IPR002053 Glycoside hydrolase, family 25 GO:0003796|GO:0009253|GO:0016998 CNX65_RS33980 84ca9653c5179c45bed670d6eb828e9b 262 Gene3D G3DSA:3.20.20.80 46 262 5.7E-64 T 28-03-2018 CNX65_RS33980 84ca9653c5179c45bed670d6eb828e9b 262 SMART SM00641 62 171 4.2E-48 T 28-03-2018 IPR018077 Glycoside hydrolase, family 25 subgroup CNX65_RS11875 9ce18548a74bb7471457c9662aa7e4e2 307 Pfam PF04347 Flagellar biosynthesis protein, FliO 31 91 1.0E-9 T 28-03-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 CNX65_RS30940 6da384e4d353a65e438a3d087a0596e3 356 Pfam PF13020 Domain of unknown function (DUF3883) 241 312 3.8E-7 T 28-03-2018 IPR024975 Domain of unknown function DUF3883 CNX65_RS30940 6da384e4d353a65e438a3d087a0596e3 356 Pfam PF12102 Domain of unknown function (DUF3578) 8 192 2.0E-39 T 28-03-2018 IPR021961 Protein of unknown function DUF3578 CNX65_RS17225 1a6c673fe4707026976a48763672cd3a 117 SUPERFAMILY SSF46785 5 92 2.6E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17225 1a6c673fe4707026976a48763672cd3a 117 Gene3D G3DSA:1.10.10.10 3 77 1.0E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS17225 1a6c673fe4707026976a48763672cd3a 117 SMART SM00345 16 75 3.0E-13 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS17225 1a6c673fe4707026976a48763672cd3a 117 Pfam PF00392 Bacterial regulatory proteins, gntR family 12 75 3.7E-16 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS33775 43baad2a0d3a202337d7f66619003b13 211 Pfam PF08768 Domain of unknown function (DUF1794) 56 208 4.0E-53 T 28-03-2018 IPR014878 Domain of unknown function DUF1794 CNX65_RS33775 43baad2a0d3a202337d7f66619003b13 211 Hamap MF_01297 UPF0678 fatty acid-binding protein-like protein . 47 210 34.663 T 28-03-2018 IPR022939 Uncharacterised protein family UPF0678 CNX65_RS33775 43baad2a0d3a202337d7f66619003b13 211 Gene3D G3DSA:2.40.128.20 17 211 6.9E-70 T 28-03-2018 IPR012674 Calycin CNX65_RS33775 43baad2a0d3a202337d7f66619003b13 211 SUPERFAMILY SSF50814 51 209 2.02E-45 T 28-03-2018 IPR012674 Calycin CNX65_RS03555 0c94492f853955cb92f9d7803a215c72 259 Pfam PF01255 Putative undecaprenyl diphosphate synthase 35 258 4.3E-69 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS03555 0c94492f853955cb92f9d7803a215c72 259 SUPERFAMILY SSF64005 24 253 1.02E-71 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS03555 0c94492f853955cb92f9d7803a215c72 259 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 204 221 - T 28-03-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199 CNX65_RS03555 0c94492f853955cb92f9d7803a215c72 259 Gene3D G3DSA:3.40.1180.10 15 259 3.1E-78 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS03555 0c94492f853955cb92f9d7803a215c72 259 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 28 259 35.408 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS03555 0c94492f853955cb92f9d7803a215c72 259 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 29 258 5.9E-63 T 28-03-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 CNX65_RS10920 d4a643e2aa2f7eccb1d179229b76128e 429 Gene3D G3DSA:3.90.1720.10 292 429 3.1E-31 T 28-03-2018 CNX65_RS10920 d4a643e2aa2f7eccb1d179229b76128e 429 Pfam PF00877 NlpC/P60 family 306 424 6.2E-25 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CNX65_RS10920 d4a643e2aa2f7eccb1d179229b76128e 429 SUPERFAMILY SSF54001 291 417 5.89E-31 T 28-03-2018 CNX65_RS28985 58cf97652f051d783fe03a090fc72dab 281 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 237 263 - T 28-03-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 CNX65_RS28985 58cf97652f051d783fe03a090fc72dab 281 Pfam PF01148 Cytidylyltransferase family 24 279 2.0E-53 T 28-03-2018 CNX65_RS22090 1e11c096f42bedfb34320627bf0e5572 397 Pfam PF13449 Esterase-like activity of phytase 74 363 3.2E-65 T 28-03-2018 IPR027372 Phytase-like domain CNX65_RS22090 1e11c096f42bedfb34320627bf0e5572 397 Gene3D G3DSA:2.120.10.30 141 363 5.3E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 SMART SM00560 578 710 4.7E-4 T 28-03-2018 IPR006558 LamG-like jellyroll fold CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 Gene3D G3DSA:2.60.120.200 494 719 2.1E-31 T 28-03-2018 CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 329 452 8.2E-21 T 28-03-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 SUPERFAMILY SSF51306 333 389 6.8E-6 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 SUPERFAMILY SSF49899 507 717 1.04E-25 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 572 713 8.3E-22 T 28-03-2018 CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 Pfam PF00717 Peptidase S24-like 338 391 8.7E-7 T 28-03-2018 IPR015927 Peptidase S24/S26A/S26B/S26C CNX65_RS21990 690cc69e3d555d0ceab5bc0a00b399bc 719 Gene3D G3DSA:2.10.109.10 333 423 6.5E-10 T 28-03-2018 CNX65_RS26230 ac4ba6cf97f592fefb596580bbd738f9 242 SUPERFAMILY SSF53335 17 242 3.65E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS26230 ac4ba6cf97f592fefb596580bbd738f9 242 Pfam PF13649 Methyltransferase domain 39 132 2.5E-11 T 28-03-2018 CNX65_RS26230 ac4ba6cf97f592fefb596580bbd738f9 242 Gene3D G3DSA:3.40.50.150 9 241 1.1E-28 T 28-03-2018 CNX65_RS24515 30f220ff6fbf2b0eb0211b72d44485d6 154 SUPERFAMILY SSF46785 7 139 2.35E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24515 30f220ff6fbf2b0eb0211b72d44485d6 154 SMART SM00347 24 128 4.1E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24515 30f220ff6fbf2b0eb0211b72d44485d6 154 Gene3D G3DSA:1.10.10.10 2 132 1.2E-16 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS24515 30f220ff6fbf2b0eb0211b72d44485d6 154 Pfam PF01047 MarR family 41 93 2.1E-10 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24515 30f220ff6fbf2b0eb0211b72d44485d6 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 5.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24515 30f220ff6fbf2b0eb0211b72d44485d6 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 5.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS24515 30f220ff6fbf2b0eb0211b72d44485d6 154 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 5.0E-5 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 136 144 5.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 SUPERFAMILY SSF51735 3 249 2.05E-58 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 Pfam PF00106 short chain dehydrogenase 7 186 2.2E-45 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 Gene3D G3DSA:3.40.50.720 162 238 1.1E-16 T 28-03-2018 CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 8.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 201 221 8.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 130 146 8.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 8.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 8.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 8.4E-24 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS04010 f7818f06d59d7397c405dae9379c8079 296 Gene3D G3DSA:3.40.50.720 3 161 6.3E-41 T 28-03-2018 CNX65_RS04575 f738bd4f7681b322ff1b7b06a000e15c 100 Gene3D G3DSA:2.40.160.20 10 91 0.039 T 28-03-2018 IPR011250 Outer membrane protein/outer membrane enzyme PagP, beta-barrel GO:0016021 CNX65_RS09495 e4a24e32beec38aaf17bb765880cdc89 90 Pfam PF04226 Transglycosylase associated protein 33 82 1.7E-9 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CNX65_RS14575 b8112420345f4c0397b201a25baa4d12 104 SUPERFAMILY SSF103481 6 101 9.81E-15 T 28-03-2018 CNX65_RS14575 b8112420345f4c0397b201a25baa4d12 104 Pfam PF00893 Small Multidrug Resistance protein 1 93 4.0E-21 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CNX65_RS06040 80208a39bc890afbdf2a4273a9fdd54d 160 Gene3D G3DSA:3.40.630.30 6 159 1.2E-24 T 28-03-2018 CNX65_RS06040 80208a39bc890afbdf2a4273a9fdd54d 160 Pfam PF00583 Acetyltransferase (GNAT) family 38 142 3.1E-13 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS06040 80208a39bc890afbdf2a4273a9fdd54d 160 SUPERFAMILY SSF55729 14 147 3.37E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS06440 0ac33062fef432a29cc3110ee684bf2a 386 SUPERFAMILY SSF56512 16 380 3.53E-152 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CNX65_RS06440 0ac33062fef432a29cc3110ee684bf2a 386 Gene3D G3DSA:3.90.340.10 2 141 2.7E-44 T 28-03-2018 CNX65_RS06440 0ac33062fef432a29cc3110ee684bf2a 386 Pfam PF02898 Nitric oxide synthase, oxygenase domain 24 375 8.4E-146 T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CNX65_RS06440 0ac33062fef432a29cc3110ee684bf2a 386 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 81 88 - T 28-03-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 CNX65_RS06440 0ac33062fef432a29cc3110ee684bf2a 386 Gene3D G3DSA:3.90.1230.10 212 322 7.3E-53 T 28-03-2018 CNX65_RS06440 0ac33062fef432a29cc3110ee684bf2a 386 PIRSF PIRSF037219 19 382 1.0E-150 T 28-03-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.13.165|KEGG: 00330+1.14.13.165 CNX65_RS07700 f849c7311fb414a2ab8da1537b0d4193 350 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 13 348 2.9E-119 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CNX65_RS07700 f849c7311fb414a2ab8da1537b0d4193 350 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 12 348 8.1E-125 T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CNX65_RS07700 f849c7311fb414a2ab8da1537b0d4193 350 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 10 350 45.932 T 28-03-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CNX65_RS07700 f849c7311fb414a2ab8da1537b0d4193 350 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 143 159 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CNX65_RS07700 f849c7311fb414a2ab8da1537b0d4193 350 Gene3D G3DSA:3.20.20.210 8 350 1.9E-102 T 28-03-2018 CNX65_RS07700 f849c7311fb414a2ab8da1537b0d4193 350 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 26 35 - T 28-03-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 CNX65_RS07700 f849c7311fb414a2ab8da1537b0d4193 350 SUPERFAMILY SSF51726 10 348 1.74E-101 T 28-03-2018 CNX65_RS19485 f7ce26a44f0a456e6dad23a753b1d40a 126 Gene3D G3DSA:1.10.10.10 19 119 3.2E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19485 f7ce26a44f0a456e6dad23a753b1d40a 126 Pfam PF01638 HxlR-like helix-turn-helix 21 107 4.9E-20 T 28-03-2018 IPR002577 Helix-turn-helix, HxlR type CNX65_RS19485 f7ce26a44f0a456e6dad23a753b1d40a 126 SUPERFAMILY SSF46785 7 114 5.27E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29990 7ad87a7f786355d11f603125e80c00a9 539 Pfam PF08386 TAP-like protein 415 514 6.3E-23 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS29990 7ad87a7f786355d11f603125e80c00a9 539 SUPERFAMILY SSF53474 104 151 5.8E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29990 7ad87a7f786355d11f603125e80c00a9 539 SUPERFAMILY SSF53474 193 247 5.8E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29990 7ad87a7f786355d11f603125e80c00a9 539 SUPERFAMILY SSF53474 407 502 5.8E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29990 7ad87a7f786355d11f603125e80c00a9 539 Pfam PF00561 alpha/beta hydrolase fold 103 252 3.7E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS29990 7ad87a7f786355d11f603125e80c00a9 539 Gene3D G3DSA:3.40.50.1820 84 504 1.2E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 Pfam PF00005 ABC transporter 276 427 1.1E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 Pfam PF00005 ABC transporter 21 170 1.7E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 SMART SM00382 282 476 2.6E-4 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 SMART SM00382 30 218 8.4E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 SUPERFAMILY SSF52540 268 481 8.34E-47 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 ProSitePatterns PS00211 ABC transporters family signature. 400 414 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 SUPERFAMILY SSF52540 4 228 7.94E-56 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 Gene3D G3DSA:3.40.50.300 2 255 6.5E-50 T 28-03-2018 CNX65_RS09260 db6584c7b11f6fb546a46865e907d192 505 Gene3D G3DSA:3.40.50.300 262 486 7.3E-39 T 28-03-2018 CNX65_RS26870 71f211cea045194d2102efcf90b65ed1 65 Pfam PF04149 Domain of unknown function (DUF397) 13 63 8.1E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS00555 8ba69f1811d80bcd7c13a40080d49fa7 116 SUPERFAMILY SSF55486 4 115 5.28E-39 T 28-03-2018 CNX65_RS00555 8ba69f1811d80bcd7c13a40080d49fa7 116 Pfam PF06262 Zincin-like metallopeptidase 29 115 7.1E-34 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CNX65_RS15580 0cda7eb5c8223654359cea9200a4f1cb 370 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 160 363 4.7E-36 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS15580 0cda7eb5c8223654359cea9200a4f1cb 370 SUPERFAMILY SSF161098 140 348 7.41E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS15580 0cda7eb5c8223654359cea9200a4f1cb 370 Gene3D G3DSA:1.10.3720.10 130 362 3.0E-26 T 28-03-2018 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 Gene3D G3DSA:1.20.210.10 23 536 1.5E-196 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 36 479 2.0E-148 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 234 255 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 301 316 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 386 405 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 144 156 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 27 52 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 101 125 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 176 194 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 358 376 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 255 276 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 205 224 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 436 457 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 74 97 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 PRINTS PR01165 Cytochrome c oxidase subunit I signature 323 344 2.0E-100 T 28-03-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0005506|GO:0009055|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 257 311 - T 28-03-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 29 532 8.4E-216 T 28-03-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005507|GO:0005886|GO:0006810|GO:0022900|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CNX65_RS04960 89289486150daaee85f377fdc24cd7f9 596 SUPERFAMILY SSF81442 25 534 1.19E-174 T 28-03-2018 IPR023616 Cytochrome c oxidase-like, subunit I domain GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS14905 b1a6ecdf71b4142460b8e49c78b0449a 198 Gene3D G3DSA:3.40.630.30 5 150 3.8E-8 T 28-03-2018 CNX65_RS14905 b1a6ecdf71b4142460b8e49c78b0449a 198 SUPERFAMILY SSF55729 12 116 2.72E-7 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS06335 ba3e69392f027a202502b8582ec80abd 241 Pfam PF03575 Peptidase family S51 34 204 1.1E-22 T 28-03-2018 IPR005320 Peptidase S51 GO:0006508|GO:0008236 CNX65_RS06335 ba3e69392f027a202502b8582ec80abd 241 Gene3D G3DSA:3.40.50.880 3 239 1.4E-34 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS06335 ba3e69392f027a202502b8582ec80abd 241 SUPERFAMILY SSF52317 35 209 8.93E-17 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS03595 1c01be86903c849eb88fb318ece57240 144 SUPERFAMILY SSF141523 40 142 3.92E-22 T 28-03-2018 CNX65_RS03595 1c01be86903c849eb88fb318ece57240 144 Pfam PF03734 L,D-transpeptidase catalytic domain 39 142 5.4E-13 T 28-03-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 CNX65_RS03595 1c01be86903c849eb88fb318ece57240 144 Gene3D G3DSA:2.40.440.10 34 143 1.3E-18 T 28-03-2018 CNX65_RS18680 6e11e71fcd67b62851a69ad1e267c993 215 SUPERFAMILY SSF53639 4 207 4.32E-51 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS18680 6e11e71fcd67b62851a69ad1e267c993 215 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 5 182 2.7E-42 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS18680 6e11e71fcd67b62851a69ad1e267c993 215 SMART SM01007 5 183 2.2E-50 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS18680 6e11e71fcd67b62851a69ad1e267c993 215 Gene3D G3DSA:3.40.225.10 2 209 2.0E-48 T 28-03-2018 IPR001303 Class II aldolase/adducin N-terminal CNX65_RS33060 e5c5bca3dc0b55ed5f1bc29cef9ffef8 69 Gene3D G3DSA:1.10.1660.10 6 64 6.8E-13 T 28-03-2018 CNX65_RS33060 e5c5bca3dc0b55ed5f1bc29cef9ffef8 69 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 9 58 4.8E-12 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CNX65_RS33060 e5c5bca3dc0b55ed5f1bc29cef9ffef8 69 Pfam PF12728 Helix-turn-helix domain 9 56 4.2E-11 T 28-03-2018 CNX65_RS33060 e5c5bca3dc0b55ed5f1bc29cef9ffef8 69 SUPERFAMILY SSF46955 8 63 1.47E-11 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 ProSitePatterns PS01095 Chitinases family 18 active site. 331 339 - T 28-03-2018 IPR001579 Glycoside hydrolase, chitinase active site GO:0004553|GO:0005975 KEGG: 00520+3.2.1.14|MetaCyc: PWY-6855|MetaCyc: PWY-6902|MetaCyc: PWY-7822 CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 Pfam PF02018 Carbohydrate binding domain 33 149 9.1E-12 T 28-03-2018 IPR003305 Carbohydrate-binding, CenC-like GO:0016798 CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 Gene3D G3DSA:2.60.120.260 30 164 2.4E-24 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 SMART SM00636 219 492 2.1E-5 T 28-03-2018 IPR011583 Chitinase II GO:0008061 CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 Pfam PF00704 Glycosyl hydrolases family 18 222 458 1.3E-24 T 28-03-2018 IPR001223 Glycoside hydrolase family 18, catalytic domain GO:0005975 CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 SUPERFAMILY SSF51445 216 500 1.1E-53 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 SUPERFAMILY SSF49785 33 163 1.32E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS06085 6c4fb23af24aee5ac527064638d59c88 511 Gene3D G3DSA:3.20.20.80 165 510 1.3E-46 T 28-03-2018 CNX65_RS20990 32469e7f9c1d6bedf90a309783dbe064 141 SUPERFAMILY SSF46785 6 136 1.65E-31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20990 32469e7f9c1d6bedf90a309783dbe064 141 Pfam PF01475 Ferric uptake regulator family 14 127 8.8E-16 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CNX65_RS20990 32469e7f9c1d6bedf90a309783dbe064 141 Gene3D G3DSA:1.10.10.10 2 85 4.4E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15400 c7bc6907da6f6d855ab749e1b237b899 153 Gene3D G3DSA:3.10.180.10 2 152 4.3E-18 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS15400 c7bc6907da6f6d855ab749e1b237b899 153 SUPERFAMILY SSF54593 5 152 2.17E-8 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS00370 364eeccceee08d9258cf603f79651d45 528 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 36 446 2.4E-60 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS00370 364eeccceee08d9258cf603f79651d45 528 Pfam PF00474 Sodium:solute symporter family 36 447 9.6E-94 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS02265 dd0451112148edc4a258576d9b84ec79 424 Gene3D G3DSA:3.40.190.10 161 423 1.1E-39 T 28-03-2018 CNX65_RS02265 dd0451112148edc4a258576d9b84ec79 424 SUPERFAMILY SSF53850 28 423 2.55E-68 T 28-03-2018 CNX65_RS02265 dd0451112148edc4a258576d9b84ec79 424 Pfam PF13416 Bacterial extracellular solute-binding protein 56 364 1.5E-33 T 28-03-2018 CNX65_RS02265 dd0451112148edc4a258576d9b84ec79 424 Gene3D G3DSA:3.40.190.10 34 160 1.0E-16 T 28-03-2018 CNX65_RS04700 c8cd7712155994d05ba84b37b5ef789d 274 SUPERFAMILY SSF55729 103 263 1.1E-17 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS04700 c8cd7712155994d05ba84b37b5ef789d 274 Gene3D G3DSA:3.40.630.30 122 273 3.7E-20 T 28-03-2018 CNX65_RS04700 c8cd7712155994d05ba84b37b5ef789d 274 Pfam PF00583 Acetyltransferase (GNAT) family 169 256 1.7E-8 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS14585 ee6703b94ab9215e12cb57a65bbea220 227 Gene3D G3DSA:1.10.357.10 1 224 7.3E-26 T 28-03-2018 CNX65_RS14585 ee6703b94ab9215e12cb57a65bbea220 227 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 60 1.0E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14585 ee6703b94ab9215e12cb57a65bbea220 227 SUPERFAMILY SSF46689 2 76 5.64E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS00810 11839d65bb093961a8b7ad88ecb4848e 475 Gene3D G3DSA:3.30.470.20 132 449 2.6E-14 T 28-03-2018 CNX65_RS00810 11839d65bb093961a8b7ad88ecb4848e 475 SUPERFAMILY SSF56059 182 345 2.08E-15 T 28-03-2018 CNX65_RS26440 66056b4713bf3f51f7a04e6af72cf5ba 173 SUPERFAMILY SSF52096 59 167 1.66E-16 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS26440 66056b4713bf3f51f7a04e6af72cf5ba 173 Gene3D G3DSA:3.90.226.10 119 172 1.6E-5 T 28-03-2018 CNX65_RS26440 66056b4713bf3f51f7a04e6af72cf5ba 173 Gene3D G3DSA:3.90.226.10 46 118 1.8E-8 T 28-03-2018 CNX65_RS26965 8db092dac0f1976334c5339ce6d065d4 195 SUPERFAMILY SSF52540 16 190 2.06E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26965 8db092dac0f1976334c5339ce6d065d4 195 Gene3D G3DSA:3.40.50.300 8 193 4.9E-19 T 28-03-2018 CNX65_RS26965 8db092dac0f1976334c5339ce6d065d4 195 Pfam PF03029 Conserved hypothetical ATP binding protein 21 188 8.2E-27 T 28-03-2018 IPR004130 GPN-loop GTPase CNX65_RS05575 302bb2a776cff71ee633e10e94c19074 395 Pfam PF07690 Major Facilitator Superfamily 9 315 1.3E-15 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS05575 302bb2a776cff71ee633e10e94c19074 395 Gene3D G3DSA:1.20.1250.20 5 190 2.0E-8 T 28-03-2018 CNX65_RS05575 302bb2a776cff71ee633e10e94c19074 395 SUPERFAMILY SSF103473 6 381 2.35E-33 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS05575 302bb2a776cff71ee633e10e94c19074 395 Gene3D G3DSA:1.20.1250.20 194 393 2.3E-18 T 28-03-2018 CNX65_RS20200 59e2868d40183c5d672341582aaf6acb 478 Pfam PF00067 Cytochrome P450 227 388 4.3E-14 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS20200 59e2868d40183c5d672341582aaf6acb 478 Gene3D G3DSA:1.10.630.10 95 398 1.9E-25 T 28-03-2018 CNX65_RS20200 59e2868d40183c5d672341582aaf6acb 478 SUPERFAMILY SSF48264 115 379 2.1E-30 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS01790 b08cbb5c42370a69047caec23666eb0e 305 SUPERFAMILY SSF161098 62 290 5.63E-60 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS01790 b08cbb5c42370a69047caec23666eb0e 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 99 295 7.8E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS01790 b08cbb5c42370a69047caec23666eb0e 305 Gene3D G3DSA:1.20.58.370 2 41 3.8E-4 T 28-03-2018 IPR035277 Maltose transport system permease protein MalF N-terminal domain CNX65_RS01790 b08cbb5c42370a69047caec23666eb0e 305 Gene3D G3DSA:1.10.3720.10 71 302 3.8E-49 T 28-03-2018 CNX65_RS09690 99b799ba7baaf243357965800b4f1621 306 Gene3D G3DSA:3.40.50.300 7 278 6.1E-58 T 28-03-2018 CNX65_RS09690 99b799ba7baaf243357965800b4f1621 306 SUPERFAMILY SSF52540 6 225 4.17E-57 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS09690 99b799ba7baaf243357965800b4f1621 306 SMART SM00382 34 210 3.2E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS09690 99b799ba7baaf243357965800b4f1621 306 Pfam PF00005 ABC transporter 26 162 6.0E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS09690 99b799ba7baaf243357965800b4f1621 306 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS02205 885b8fc20595cefb805701f790768882 330 Pfam PF01066 CDP-alcohol phosphatidyltransferase 11 74 7.9E-12 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS02205 885b8fc20595cefb805701f790768882 330 Pfam PF08009 CDP-alcohol phosphatidyltransferase 2 193 229 2.1E-5 T 28-03-2018 IPR012616 CDP-alcohol phosphatidyltransferase, C-terminal CNX65_RS02205 885b8fc20595cefb805701f790768882 330 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 16 181 6.2E-36 T 28-03-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 CNX65_RS02205 885b8fc20595cefb805701f790768882 330 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 52 74 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS11100 598af7f95807f456aa8a3d551204f04a 102 Pfam PF03091 CutA1 divalent ion tolerance protein 1 98 2.5E-35 T 28-03-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 CNX65_RS11100 598af7f95807f456aa8a3d551204f04a 102 Gene3D G3DSA:3.30.70.120 1 102 1.6E-36 T 28-03-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal CNX65_RS11100 598af7f95807f456aa8a3d551204f04a 102 SUPERFAMILY SSF54913 2 100 2.97E-35 T 28-03-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta CNX65_RS04870 90a827b729b22b9ae3a9da22d00d8a93 125 Gene3D G3DSA:3.30.565.10 2 117 7.7E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS04870 90a827b729b22b9ae3a9da22d00d8a93 125 SUPERFAMILY SSF55874 31 117 5.33E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS21070 264084e50a4eafb0f5eba20bdcabacac 409 Pfam PF01494 FAD binding domain 1 177 2.8E-12 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS21070 264084e50a4eafb0f5eba20bdcabacac 409 SUPERFAMILY SSF51905 268 346 2.34E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21070 264084e50a4eafb0f5eba20bdcabacac 409 SUPERFAMILY SSF51905 1 174 2.34E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21070 264084e50a4eafb0f5eba20bdcabacac 409 Gene3D G3DSA:3.50.50.60 1 349 1.8E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 Pfam PF03167 Uracil DNA glycosylase superfamily 55 210 4.4E-18 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 SUPERFAMILY SSF52141 8 222 1.09E-71 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 10 222 32.808 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 60 69 - T 28-03-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 13 215 1.8E-55 T 28-03-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 SMART SM00987 52 211 1.3E-30 T 28-03-2018 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 SMART SM00986 52 211 1.3E-30 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS29390 a8e17730871076f1b2f4b3f0046414ef 224 Gene3D G3DSA:3.40.470.10 2 224 5.8E-78 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS31710 a680d7f7c3bc6b2107650879067d4394 138 Gene3D G3DSA:1.20.1300.10 19 137 3.9E-24 T 28-03-2018 CNX65_RS31710 a680d7f7c3bc6b2107650879067d4394 138 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 8 120 9.5E-16 T 28-03-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS31710 a680d7f7c3bc6b2107650879067d4394 138 SUPERFAMILY SSF81343 9 132 4.8E-33 T 28-03-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 CNX65_RS35050 95dc6c48bdbbcf485061e8f54938df24 223 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 22 193 7.3E-41 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CNX65_RS35050 95dc6c48bdbbcf485061e8f54938df24 223 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 9 205 24.34 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CNX65_RS35050 95dc6c48bdbbcf485061e8f54938df24 223 SUPERFAMILY SSF53335 15 210 6.78E-35 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS35050 95dc6c48bdbbcf485061e8f54938df24 223 PIRSF PIRSF003078 3 211 5.9E-48 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CNX65_RS35050 95dc6c48bdbbcf485061e8f54938df24 223 Gene3D G3DSA:3.40.50.150 3 223 2.4E-34 T 28-03-2018 CNX65_RS35050 95dc6c48bdbbcf485061e8f54938df24 223 Pfam PF02527 rRNA small subunit methyltransferase G 18 192 4.3E-51 T 28-03-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 CNX65_RS33300 d9246358cb6e847b39d1e27759270a54 165 Pfam PF10722 Putative bacterial sensory transduction regulator 10 130 3.4E-25 T 28-03-2018 IPR019660 Putative sensory transduction regulator YbjN CNX65_RS33300 d9246358cb6e847b39d1e27759270a54 165 Gene3D G3DSA:3.30.1460.10 6 141 1.2E-40 T 28-03-2018 CNX65_RS33300 d9246358cb6e847b39d1e27759270a54 165 SUPERFAMILY SSF69635 7 133 4.24E-32 T 28-03-2018 CNX65_RS34105 4b306f248271d27350695b0bfe12c9bd 278 Pfam PF12079 Protein of unknown function (DUF3558) 95 272 6.2E-28 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS33760 43365e6ddcbfb58a31b964d252cec3a2 144 Pfam PF14340 Domain of unknown function (DUF4395) 7 135 2.2E-42 T 28-03-2018 IPR025508 Domain of unknown function DUF4395 CNX65_RS33760 43365e6ddcbfb58a31b964d252cec3a2 144 PIRSF PIRSF030042 51 138 4.6E-8 T 28-03-2018 IPR016942 Uncharacterised conserved protein UCP030042 CNX65_RS33760 43365e6ddcbfb58a31b964d252cec3a2 144 PIRSF PIRSF030042 2 57 3.6 T 28-03-2018 IPR016942 Uncharacterised conserved protein UCP030042 CNX65_RS23650 5e0971b7cb485a9b5cc9179b27aa71b9 313 TIGRFAM TIGR00027 mthyl_TIGR00027: methyltransferase, TIGR00027 family 21 279 1.3E-70 T 28-03-2018 IPR011610 S-adenosyl-L-methionine-dependent methyltransferase, putative GO:0008168 CNX65_RS23650 5e0971b7cb485a9b5cc9179b27aa71b9 313 Pfam PF04072 Leucine carboxyl methyltransferase 23 202 9.4E-49 T 28-03-2018 IPR007213 Methyltransferase Ppm1/Ppm2/Tcmp GO:0008168|GO:0032259 CNX65_RS23650 5e0971b7cb485a9b5cc9179b27aa71b9 313 Gene3D G3DSA:3.40.50.150 2 277 2.5E-48 T 28-03-2018 CNX65_RS23650 5e0971b7cb485a9b5cc9179b27aa71b9 313 SUPERFAMILY SSF53335 19 298 1.08E-61 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS06770 e5f53d0107208b2e12cf5558e504aa38 138 Pfam PF12270 Cytochrome c oxidase subunit IV 1 136 1.1E-52 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CNX65_RS06770 e5f53d0107208b2e12cf5558e504aa38 138 Gene3D G3DSA:1.10.287.70 86 133 2.4E-4 T 28-03-2018 CNX65_RS06770 e5f53d0107208b2e12cf5558e504aa38 138 PIRSF PIRSF017385 1 138 1.3E-50 T 28-03-2018 IPR021050 Cytochrome c oxidase subunit IV, actinobacteria GO:0004129|GO:0016021|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 SUPERFAMILY SSF100950 76 233 3.35E-19 T 28-03-2018 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 Gene3D G3DSA:3.40.50.1360 73 240 1.7E-33 T 28-03-2018 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 Gene3D G3DSA:1.10.10.10 1 72 1.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 Pfam PF08220 DeoR-like helix-turn-helix domain 7 59 5.0E-14 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 SMART SM01134 72 234 1.2E-44 T 28-03-2018 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 SMART SM00420 6 58 2.6E-15 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 SUPERFAMILY SSF46785 4 64 8.32E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.2E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.2E-6 T 28-03-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 CNX65_RS12365 2e254786d5636b09ee773dca536fc3ab 253 Pfam PF00455 DeoR C terminal sensor domain 75 232 1.3E-39 T 28-03-2018 IPR014036 DeoR C-terminal sensor domain CNX65_RS24695 ee01baa29b54b1c1f0bc5e281b66fc75 254 SUPERFAMILY SSF55797 134 253 1.15E-24 T 28-03-2018 IPR014044 CAP domain CNX65_RS24695 ee01baa29b54b1c1f0bc5e281b66fc75 254 Gene3D G3DSA:3.40.33.10 125 253 4.2E-18 T 28-03-2018 IPR014044 CAP domain CNX65_RS24695 ee01baa29b54b1c1f0bc5e281b66fc75 254 Pfam PF00188 Cysteine-rich secretory protein family 138 252 4.3E-24 T 28-03-2018 IPR014044 CAP domain CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00097 Anthranilate synthase component II signature 3 17 1.5E-34 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00097 Anthranilate synthase component II signature 74 85 1.5E-34 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00097 Anthranilate synthase component II signature 119 131 1.5E-34 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00097 Anthranilate synthase component II signature 99 107 1.5E-34 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00097 Anthranilate synthase component II signature 46 55 1.5E-34 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00097 Anthranilate synthase component II signature 164 177 1.5E-34 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 Pfam PF00117 Glutamine amidotransferase class-I 5 185 1.2E-48 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 3 185 1.1E-61 T 28-03-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain GO:0008152 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 2.8E-6 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 2.8E-6 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 3.2E-13 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 3.2E-13 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 3.2E-13 T 28-03-2018 CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 SUPERFAMILY SSF52317 1 188 3.06E-54 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS00105 e81c7c46754e6f1cfd1f293a037a7b51 213 Gene3D G3DSA:3.40.50.880 1 190 9.0E-59 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS15105 f9b882df7fc0f9b846d3c7e778d59a42 203 SUPERFAMILY SSF53335 5 188 1.84E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS15105 f9b882df7fc0f9b846d3c7e778d59a42 203 Pfam PF13649 Methyltransferase domain 39 132 1.5E-14 T 28-03-2018 CNX65_RS15105 f9b882df7fc0f9b846d3c7e778d59a42 203 Gene3D G3DSA:3.40.50.150 1 185 3.0E-27 T 28-03-2018 CNX65_RS17835 c28a5a010983e0e79671a1e432f44c13 121 SUPERFAMILY SSF54593 5 120 1.13E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS17835 c28a5a010983e0e79671a1e432f44c13 121 Gene3D G3DSA:3.10.180.10 3 118 1.5E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS21110 9163c4c092a7e63d4b20e95fcfa86a26 263 Pfam PF00459 Inositol monophosphatase family 9 255 5.8E-28 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS21110 9163c4c092a7e63d4b20e95fcfa86a26 263 Gene3D G3DSA:3.30.540.10 1 146 2.1E-23 T 28-03-2018 CNX65_RS21110 9163c4c092a7e63d4b20e95fcfa86a26 263 SUPERFAMILY SSF56655 11 257 1.83E-41 T 28-03-2018 CNX65_RS21110 9163c4c092a7e63d4b20e95fcfa86a26 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 2.8E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS21110 9163c4c092a7e63d4b20e95fcfa86a26 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 211 235 2.8E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS21110 9163c4c092a7e63d4b20e95fcfa86a26 263 PRINTS PR00377 Inositol monophosphatase superfamily signature 131 154 2.8E-17 T 28-03-2018 IPR000760 Inositol monophosphatase-like GO:0046854 CNX65_RS21110 9163c4c092a7e63d4b20e95fcfa86a26 263 Gene3D G3DSA:3.40.190.80 147 263 3.9E-16 T 28-03-2018 CNX65_RS21695 7ebf797497fdcd613e4332506b944212 144 Pfam PF00072 Response regulator receiver domain 11 129 3.2E-17 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS21695 7ebf797497fdcd613e4332506b944212 144 SMART SM00448 9 129 3.5E-24 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS21695 7ebf797497fdcd613e4332506b944212 144 SUPERFAMILY SSF52172 8 132 2.99E-29 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS21695 7ebf797497fdcd613e4332506b944212 144 Gene3D G3DSA:3.40.50.2300 4 136 5.6E-28 T 28-03-2018 CNX65_RS06035 b9584ec89230a8f9448bb99565540b9c 305 SUPERFAMILY SSF117892 108 239 5.23E-12 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS06035 b9584ec89230a8f9448bb99565540b9c 305 SMART SM00244 73 237 1.9E-10 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS06035 b9584ec89230a8f9448bb99565540b9c 305 Pfam PF01145 SPFH domain / Band 7 family 77 246 5.9E-23 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS20335 3f96f66f111925a834d224d1e8cdfd54 93 Gene3D G3DSA:1.10.8.60 44 93 1.9E-8 T 28-03-2018 CNX65_RS17960 cdc2c097f73010be8f377ace1ca2b048 541 Gene3D G3DSA:3.40.50.300 71 183 3.1E-7 T 28-03-2018 CNX65_RS17960 cdc2c097f73010be8f377ace1ca2b048 541 Gene3D G3DSA:1.25.40.10 214 538 5.6E-9 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17960 cdc2c097f73010be8f377ace1ca2b048 541 SUPERFAMILY SSF48452 410 529 1.1E-6 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS17960 cdc2c097f73010be8f377ace1ca2b048 541 SUPERFAMILY SSF52540 77 235 1.37E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10880 7446c9e87f25f492f6faa58c5077acd5 277 Pfam PF00005 ABC transporter 44 168 5.2E-14 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS10880 7446c9e87f25f492f6faa58c5077acd5 277 SMART SM00382 53 225 3.5E-9 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS10880 7446c9e87f25f492f6faa58c5077acd5 277 SUPERFAMILY SSF52540 28 215 1.99E-32 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10880 7446c9e87f25f492f6faa58c5077acd5 277 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS10880 7446c9e87f25f492f6faa58c5077acd5 277 Gene3D G3DSA:3.40.50.300 25 251 1.0E-35 T 28-03-2018 CNX65_RS16555 2f50de61c158ff4960ad6887f0b4f31b 314 Gene3D G3DSA:2.130.10.10 23 213 2.1E-12 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS16555 2f50de61c158ff4960ad6887f0b4f31b 314 Gene3D G3DSA:2.120.10.30 214 302 1.2E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS16555 2f50de61c158ff4960ad6887f0b4f31b 314 SUPERFAMILY SSF63829 7 296 2.09E-21 T 28-03-2018 CNX65_RS11375 135bf0983dc459214614394a1d0abed0 304 Pfam PF00248 Aldo/keto reductase family 40 287 8.1E-12 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS11375 135bf0983dc459214614394a1d0abed0 304 Gene3D G3DSA:3.20.20.100 1 299 3.1E-27 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS11375 135bf0983dc459214614394a1d0abed0 304 SUPERFAMILY SSF51430 35 288 1.7E-25 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS32985 797da298af3b4f752a77534d4438b02b 413 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 106 410 4.2E-68 T 28-03-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 CNX65_RS32985 797da298af3b4f752a77534d4438b02b 413 SUPERFAMILY SSF56322 40 411 4.19E-77 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS32985 797da298af3b4f752a77534d4438b02b 413 Pfam PF00425 chorismate binding enzyme 161 402 3.1E-63 T 28-03-2018 IPR015890 Chorismate-utilising enzyme, C-terminal CNX65_RS32985 797da298af3b4f752a77534d4438b02b 413 Gene3D G3DSA:3.60.120.10 33 412 4.3E-86 T 28-03-2018 IPR005801 ADC synthase GO:0009058 CNX65_RS29755 dd47a60ad97beb1d9e1065bfa9b4ce0b 391 Gene3D G3DSA:3.40.640.10 10 255 1.4E-49 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS29755 dd47a60ad97beb1d9e1065bfa9b4ce0b 391 SUPERFAMILY SSF53383 2 374 1.99E-97 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS29755 dd47a60ad97beb1d9e1065bfa9b4ce0b 391 Gene3D G3DSA:3.90.1150.10 262 380 2.0E-36 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS29755 dd47a60ad97beb1d9e1065bfa9b4ce0b 391 PIRSF PIRSF005572 1 379 1.2E-115 T 28-03-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-6823|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7250 CNX65_RS29755 dd47a60ad97beb1d9e1065bfa9b4ce0b 391 Pfam PF00266 Aminotransferase class-V 3 365 8.8E-63 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS08450 e66a3060f6ea3de406f6e47cc06e67b3 527 SMART SM00267 348 514 1.9E-53 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS08450 e66a3060f6ea3de406f6e47cc06e67b3 527 SUPERFAMILY SSF55073 364 512 1.1E-39 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS08450 e66a3060f6ea3de406f6e47cc06e67b3 527 Gene3D G3DSA:3.30.70.270 342 513 4.6E-55 T 28-03-2018 CNX65_RS08450 e66a3060f6ea3de406f6e47cc06e67b3 527 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 355 511 5.2E-36 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS08450 e66a3060f6ea3de406f6e47cc06e67b3 527 Pfam PF00990 Diguanylate cyclase, GGDEF domain 359 508 2.4E-39 T 28-03-2018 IPR000160 GGDEF domain CNX65_RS31315 776654fcc1b26f65c3c97488da5cd7e4 265 Gene3D G3DSA:3.30.70.270 123 258 2.0E-4 T 28-03-2018 CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 PRINTS PR00721 Stomatin signature 174 195 8.2E-35 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 PRINTS PR00721 Stomatin signature 111 128 8.2E-35 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 PRINTS PR00721 Stomatin signature 155 173 8.2E-35 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 PRINTS PR00721 Stomatin signature 28 50 8.2E-35 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 PRINTS PR00721 Stomatin signature 76 97 8.2E-35 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 PRINTS PR00721 Stomatin signature 131 154 8.2E-35 T 28-03-2018 IPR001972 Stomatin family GO:0016020 CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 ProSitePatterns PS01270 Band 7 protein family signature. 135 163 - T 28-03-2018 IPR018080 Band 7/stomatin-like, conserved site CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 SUPERFAMILY SSF117892 52 186 1.31E-40 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 SMART SM00244 21 179 1.7E-55 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS17350 fa8563fa60321ddbae957d104d9a959a 402 Pfam PF01145 SPFH domain / Band 7 family 25 195 2.3E-34 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS01345 8fef0e5397cba0a28219d95e1e4e2b03 61 Gene3D G3DSA:1.10.10.10 23 61 2.4E-8 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01345 8fef0e5397cba0a28219d95e1e4e2b03 61 Gene3D G3DSA:1.10.10.60 9 22 0.0015 T 28-03-2018 CNX65_RS01345 8fef0e5397cba0a28219d95e1e4e2b03 61 SUPERFAMILY SSF46955 7 58 2.08E-7 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS07945 0ce14431669349e184951498be944d47 180 Gene3D G3DSA:3.30.420.10 2 180 1.0E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS07945 0ce14431669349e184951498be944d47 180 Pfam PF00929 Exonuclease 9 174 5.7E-13 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS07945 0ce14431669349e184951498be944d47 180 SMART SM00479 7 179 4.4E-4 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS07945 0ce14431669349e184951498be944d47 180 SUPERFAMILY SSF53098 4 174 2.53E-27 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS32060 1049dbc46a547005541bec20878267cd 377 SUPERFAMILY SSF51412 9 78 1.7E-60 T 28-03-2018 CNX65_RS32060 1049dbc46a547005541bec20878267cd 377 SUPERFAMILY SSF51412 119 376 1.7E-60 T 28-03-2018 CNX65_RS32060 1049dbc46a547005541bec20878267cd 377 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 266 286 - T 28-03-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 CNX65_RS32060 1049dbc46a547005541bec20878267cd 377 Gene3D G3DSA:3.20.20.70 16 376 6.4E-47 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS32060 1049dbc46a547005541bec20878267cd 377 SMART SM01240 15 375 5.4E-17 T 28-03-2018 CNX65_RS32060 1049dbc46a547005541bec20878267cd 377 TIGRFAM TIGR01304 IMP_DH_rel_2: IMP dehydrogenase family protein 5 375 2.2E-170 T 28-03-2018 IPR005992 IMP dehydrogenase-related 2 GO:0016491|GO:0055114 CNX65_RS32060 1049dbc46a547005541bec20878267cd 377 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 18 307 8.5E-35 T 28-03-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 CNX65_RS02455 6ede9ae54525433a44fe201d1a4eedda 161 ProDom PD034580 PRECURSOR SIGNAL EXPORTED MB0899C RV0875C/MT0898 MLCB57.27C POSSIBLE 24 87 2.0E-7 T 28-03-2018 IPR024495 Protein of unknown function DUF2771 CNX65_RS02455 6ede9ae54525433a44fe201d1a4eedda 161 Pfam PF10969 Protein of unknown function (DUF2771) 19 136 7.0E-19 T 28-03-2018 IPR024495 Protein of unknown function DUF2771 CNX65_RS01805 65d941ce0fc741a2066a288fd2b3ef22 299 Gene3D G3DSA:3.40.50.1980 180 297 2.7E-20 T 28-03-2018 CNX65_RS01805 65d941ce0fc741a2066a288fd2b3ef22 299 Pfam PF01297 Zinc-uptake complex component A periplasmic 43 294 5.4E-45 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CNX65_RS01805 65d941ce0fc741a2066a288fd2b3ef22 299 SUPERFAMILY SSF53807 38 297 1.32E-50 T 28-03-2018 CNX65_RS01805 65d941ce0fc741a2066a288fd2b3ef22 299 Gene3D G3DSA:3.40.50.1980 29 179 1.9E-31 T 28-03-2018 CNX65_RS29720 83919e4b57172fb75fcb5c60dd553482 335 Gene3D G3DSA:3.20.20.210 63 331 5.1E-38 T 28-03-2018 CNX65_RS29720 83919e4b57172fb75fcb5c60dd553482 335 SUPERFAMILY SSF51726 9 328 3.01E-23 T 28-03-2018 CNX65_RS29720 83919e4b57172fb75fcb5c60dd553482 335 Pfam PF01717 Cobalamin-independent synthase, Catalytic domain 11 324 1.3E-16 T 28-03-2018 IPR002629 Cobalamin-independent methionine synthase MetE, C-terminal/archaeal GO:0003871|GO:0008270|GO:0009086 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 CNX65_RS26365 6958eea0e46e3c0f8ca32a33f7e86482 279 SUPERFAMILY SSF53335 211 236 1.41E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS26365 6958eea0e46e3c0f8ca32a33f7e86482 279 SUPERFAMILY SSF53335 11 180 1.41E-29 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS26365 6958eea0e46e3c0f8ca32a33f7e86482 279 Gene3D G3DSA:3.40.50.150 2 268 7.1E-29 T 28-03-2018 CNX65_RS26365 6958eea0e46e3c0f8ca32a33f7e86482 279 Pfam PF08241 Methyltransferase domain 65 153 8.9E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS20515 69596e1d68ad169e08b84178a878deb7 438 Gene3D G3DSA:1.10.510.10 237 346 2.7E-6 T 28-03-2018 CNX65_RS20515 69596e1d68ad169e08b84178a878deb7 438 Pfam PF03109 ABC1 family 118 225 2.4E-23 T 28-03-2018 IPR004147 UbiB domain CNX65_RS20515 69596e1d68ad169e08b84178a878deb7 438 Gene3D G3DSA:3.30.200.20 101 236 5.6E-20 T 28-03-2018 CNX65_RS20515 69596e1d68ad169e08b84178a878deb7 438 SUPERFAMILY SSF56112 189 307 1.92E-22 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS20515 69596e1d68ad169e08b84178a878deb7 438 SUPERFAMILY SSF56112 114 155 1.92E-22 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS09795 3a2fbf97624786bee298e388cd26e588 292 Gene3D G3DSA:3.40.50.1220 19 292 1.9E-66 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS09795 3a2fbf97624786bee298e388cd26e588 292 Pfam PF02146 Sir2 family 39 240 6.1E-46 T 28-03-2018 IPR003000 Sirtuin family GO:0070403 CNX65_RS09795 3a2fbf97624786bee298e388cd26e588 292 Hamap MF_01967 NAD-dependent protein deacetylase [cobB]. 16 285 62.12 T 28-03-2018 IPR026587 Sirtuin, class II Reactome: R-HSA-2151201 CNX65_RS09795 3a2fbf97624786bee298e388cd26e588 292 SUPERFAMILY SSF52467 28 286 3.27E-75 T 28-03-2018 IPR029035 DHS-like NAD/FAD-binding domain CNX65_RS15445 6f6024ffcfb7fb7c1730528752ee377f 329 Pfam PF02653 Branched-chain amino acid transport system / permease component 41 300 1.3E-43 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS15445 6f6024ffcfb7fb7c1730528752ee377f 329 Gene3D G3DSA:1.10.3470.10 37 306 2.4E-30 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS00435 d824d0110b623e5f1fdcb067a89d7edb 252 SUPERFAMILY SSF50475 56 248 5.49E-19 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS00435 d824d0110b623e5f1fdcb067a89d7edb 252 Gene3D G3DSA:3.20.180.10 155 244 4.0E-21 T 28-03-2018 IPR019595 Domain of unknown function DUF2470 CNX65_RS00435 d824d0110b623e5f1fdcb067a89d7edb 252 Pfam PF10615 Protein of unknown function (DUF2470) 168 239 3.1E-7 T 28-03-2018 IPR019595 Domain of unknown function DUF2470 CNX65_RS17845 46e0eef7e6fc2c82a2f0f4e0ae75aa98 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 6 259 2.1E-84 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CNX65_RS17845 46e0eef7e6fc2c82a2f0f4e0ae75aa98 274 Pfam PF02673 Bacitracin resistance protein BacA 6 261 5.3E-82 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CNX65_RS17845 46e0eef7e6fc2c82a2f0f4e0ae75aa98 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 1 266 18.107 T 28-03-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 203 244 - T 28-03-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 Gene3D G3DSA:1.10.10.60 206 253 1.6E-11 T 28-03-2018 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 SUPERFAMILY SSF46689 202 251 2.28E-10 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 SMART SM00342 166 248 2.6E-25 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 232 248 6.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 217 232 6.8E-5 T 28-03-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 Gene3D G3DSA:1.10.10.60 21 205 1.3E-8 T 28-03-2018 CNX65_RS22255 96366b137cb00011bd299de4b771f0e6 253 Pfam PF12833 Helix-turn-helix domain 172 249 2.4E-23 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS07110 0ca591a4330d5dc759d5264be264fee0 367 Gene3D G3DSA:2.130.10.120 189 309 0.0043 T 28-03-2018 CNX65_RS07110 0ca591a4330d5dc759d5264be264fee0 367 Gene3D G3DSA:2.120.10.30 30 173 3.7E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS07110 0ca591a4330d5dc759d5264be264fee0 367 SUPERFAMILY SSF50952 199 278 2.35E-10 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CNX65_RS07110 0ca591a4330d5dc759d5264be264fee0 367 SUPERFAMILY SSF50952 49 161 2.35E-10 T 28-03-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 CNX65_RS00115 ff8bb4580f985d8d5b75d817218cea21 552 SMART SM00220 12 272 3.3E-53 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS00115 ff8bb4580f985d8d5b75d817218cea21 552 SUPERFAMILY SSF56112 9 352 7.96E-71 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS00115 ff8bb4580f985d8d5b75d817218cea21 552 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 137 149 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS00115 ff8bb4580f985d8d5b75d817218cea21 552 Gene3D G3DSA:3.30.200.20 4 102 5.1E-18 T 28-03-2018 CNX65_RS00115 ff8bb4580f985d8d5b75d817218cea21 552 Pfam PF00069 Protein kinase domain 13 261 5.3E-42 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS00115 ff8bb4580f985d8d5b75d817218cea21 552 Gene3D G3DSA:1.10.510.10 103 365 7.0E-48 T 28-03-2018 CNX65_RS14945 aafdc56d4e75c983508577c75243c1db 401 Gene3D G3DSA:3.30.565.10 278 399 6.3E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS14945 aafdc56d4e75c983508577c75243c1db 401 Pfam PF07730 Histidine kinase 185 266 2.3E-10 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS14945 aafdc56d4e75c983508577c75243c1db 401 SUPERFAMILY SSF55874 311 384 3.72E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 Gene3D G3DSA:1.10.287.950 308 519 8.1E-40 T 28-03-2018 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 Gene3D G3DSA:1.20.120.30 24 183 9.5E-10 T 28-03-2018 IPR035440 Methyl-accepting chemotaxis protein, four helix bundle domain CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 SMART SM00283 271 525 6.5E-48 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 Pfam PF00672 HAMP domain 214 255 1.5E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 Pfam PF12729 Four helix bundle sensory module for signal transduction 5 182 1.3E-20 T 28-03-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 SMART SM00304 211 263 1.8E-6 T 28-03-2018 IPR003660 HAMP domain GO:0004871|GO:0007165|GO:0016021 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 SUPERFAMILY SSF58104 231 524 5.1E-57 T 28-03-2018 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 299 328 3.5E-5 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 398 427 3.5E-5 T 28-03-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004871|GO:0006935|GO:0007165|GO:0016020 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 Gene3D G3DSA:1.20.1480.30 209 307 3.1E-5 T 28-03-2018 CNX65_RS15675 6e7671913ca87e292a9ec1d15c747795 526 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 331 489 3.3E-30 T 28-03-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0004871|GO:0007165|GO:0016020 CNX65_RS09995 2ca116f03c953a5565a05e947733e9bc 368 SUPERFAMILY SSF53448 326 339 1.5E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS09995 2ca116f03c953a5565a05e947733e9bc 368 SUPERFAMILY SSF53448 5 268 1.5E-51 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS09995 2ca116f03c953a5565a05e947733e9bc 368 Pfam PF00483 Nucleotidyl transferase 7 265 1.5E-33 T 28-03-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 CNX65_RS09995 2ca116f03c953a5565a05e947733e9bc 368 Gene3D G3DSA:3.90.550.10 1 271 1.7E-45 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS21445 92e32a07f716e57899d20cae0a609c82 124 SMART SM00418 25 103 3.3E-26 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21445 92e32a07f716e57899d20cae0a609c82 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 74 89 1.5E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21445 92e32a07f716e57899d20cae0a609c82 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 27 42 1.5E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21445 92e32a07f716e57899d20cae0a609c82 124 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 74 1.5E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21445 92e32a07f716e57899d20cae0a609c82 124 SUPERFAMILY SSF46785 15 102 2.1E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21445 92e32a07f716e57899d20cae0a609c82 124 Gene3D G3DSA:1.10.10.10 2 119 1.3E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21445 92e32a07f716e57899d20cae0a609c82 124 Pfam PF01022 Bacterial regulatory protein, arsR family 33 76 2.7E-11 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 Gene3D G3DSA:3.50.50.60 247 334 1.5E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 Gene3D G3DSA:1.10.1060.10 4 153 4.8E-38 T 28-03-2018 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 487 1.9E-188 T 28-03-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 37 141 1.4E-20 T 28-03-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 SUPERFAMILY SSF51971 153 414 7.46E-68 T 28-03-2018 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 154 469 8.7E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 SUPERFAMILY SSF46548 6 164 1.52E-32 T 28-03-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 7.1E-24 T 28-03-2018 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 PRINTS PR00419 Adrenodoxin reductase family signature 155 177 7.1E-24 T 28-03-2018 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 PRINTS PR00419 Adrenodoxin reductase family signature 178 191 7.1E-24 T 28-03-2018 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 PRINTS PR00419 Adrenodoxin reductase family signature 220 230 7.1E-24 T 28-03-2018 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 Gene3D G3DSA:3.50.50.60 335 482 4.0E-23 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS27895 ca83c3358c6720538a6ecccb0e68701a 500 Gene3D G3DSA:3.40.50.720 154 246 1.0E-22 T 28-03-2018 CNX65_RS12520 79e0895764e734ab7308276b30933be7 220 Pfam PF14016 Protein of unknown function (DUF4232) 80 211 1.0E-30 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CNX65_RS26635 0e2f6ab575b6caa76c841e102576772b 401 SUPERFAMILY SSF103473 13 391 1.96E-34 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS26635 0e2f6ab575b6caa76c841e102576772b 401 Pfam PF05977 Transmembrane secretion effector 27 381 3.3E-18 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS26635 0e2f6ab575b6caa76c841e102576772b 401 Gene3D G3DSA:1.20.1250.20 191 386 7.6E-16 T 28-03-2018 CNX65_RS26635 0e2f6ab575b6caa76c841e102576772b 401 Gene3D G3DSA:1.20.1250.20 6 188 1.4E-12 T 28-03-2018 CNX65_RS00495 bbcba481b72d3a813839de3bee464c15 160 Pfam PF00583 Acetyltransferase (GNAT) family 36 117 5.4E-17 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS00495 bbcba481b72d3a813839de3bee464c15 160 Gene3D G3DSA:3.40.630.30 3 136 7.2E-20 T 28-03-2018 CNX65_RS00495 bbcba481b72d3a813839de3bee464c15 160 SUPERFAMILY SSF55729 2 146 3.95E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS00495 bbcba481b72d3a813839de3bee464c15 160 PIRSF PIRSF037663 1 143 7.6E-12 T 28-03-2018 IPR017255 Acetyltransferase, GNAT, predicted CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 SUPERFAMILY SSF51735 2 233 1.29E-70 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 178 1.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 1.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 1.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 195 215 1.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 1.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 68 79 1.2E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 230 4.5E-57 T 28-03-2018 CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 3.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 68 79 3.5E-8 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 Gene3D G3DSA:3.40.50.720 41 242 5.3E-58 T 28-03-2018 CNX65_RS23240 9867b808fb3b866d1ab841d6995f15fe 267 Gene3D G3DSA:3.40.50.720 1 40 1.7E-6 T 28-03-2018 CNX65_RS31065 baf12d267fdf126424a8b0981f8d0be8 222 SUPERFAMILY SSF69754 1 107 7.32E-25 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS31065 baf12d267fdf126424a8b0981f8d0be8 222 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 222 23.26 T 28-03-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid CNX65_RS31065 baf12d267fdf126424a8b0981f8d0be8 222 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 165 218 2.9E-22 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CNX65_RS31065 baf12d267fdf126424a8b0981f8d0be8 222 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 7.5E-29 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS31065 baf12d267fdf126424a8b0981f8d0be8 222 Gene3D G3DSA:3.30.160.100 1 105 1.0E-26 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS31065 baf12d267fdf126424a8b0981f8d0be8 222 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 99 5.5E-21 T 28-03-2018 IPR003489 Ribosomal protein S30Ae/sigma 54 modulation protein GO:0044238 CNX65_RS14445 fd9eda3a93e69a94acd97bec34ef6f39 799 SUPERFAMILY SSF55073 3 127 4.24E-8 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS14445 fd9eda3a93e69a94acd97bec34ef6f39 799 Gene3D G3DSA:3.30.70.1230 2 162 1.9E-7 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS01685 2d5cfceaf08eeeb1fc35ab9df0987e42 259 SUPERFAMILY SSF53335 17 169 3.07E-32 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS01685 2d5cfceaf08eeeb1fc35ab9df0987e42 259 Pfam PF08241 Methyltransferase domain 52 141 2.2E-18 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS01685 2d5cfceaf08eeeb1fc35ab9df0987e42 259 Gene3D G3DSA:3.40.50.150 1 243 5.9E-32 T 28-03-2018 CNX65_RS29045 1245329cc0cfc402d672153b0fc7827f 258 Hamap MF_00052_B Ribonuclease HII [rnhB]. 30 211 34.142 T 28-03-2018 IPR022898 Ribonuclease HII GO:0004523 CNX65_RS29045 1245329cc0cfc402d672153b0fc7827f 258 Pfam PF01351 Ribonuclease HII 32 211 2.0E-35 T 28-03-2018 IPR024567 Ribonuclease HII/HIII domain CNX65_RS29045 1245329cc0cfc402d672153b0fc7827f 258 Gene3D G3DSA:3.30.420.10 7 221 1.8E-57 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS29045 1245329cc0cfc402d672153b0fc7827f 258 SUPERFAMILY SSF53098 23 215 5.92E-58 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS08990 8070594e7af3f426099da847ddfbac56 205 Pfam PF03364 Polyketide cyclase / dehydrase and lipid transport 10 128 3.0E-18 T 28-03-2018 IPR005031 Coenzyme Q-binding protein COQ10, START domain Reactome: R-HSA-611105 CNX65_RS08990 8070594e7af3f426099da847ddfbac56 205 SUPERFAMILY SSF55961 3 142 4.08E-26 T 28-03-2018 CNX65_RS08990 8070594e7af3f426099da847ddfbac56 205 Gene3D G3DSA:3.30.530.20 1 160 2.1E-20 T 28-03-2018 IPR023393 START-like domain CNX65_RS18575 4d53a262f7a63b9e283d42de649f4159 319 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 5 318 1.6E-86 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CNX65_RS18575 4d53a262f7a63b9e283d42de649f4159 319 Pfam PF00296 Luciferase-like monooxygenase 9 291 7.5E-43 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS18575 4d53a262f7a63b9e283d42de649f4159 319 SUPERFAMILY SSF51679 4 318 5.1E-50 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS18575 4d53a262f7a63b9e283d42de649f4159 319 TIGRFAM TIGR03885 flavin_revert: probable non-F420 flavinoid oxidoreductase 5 317 7.9E-144 T 28-03-2018 IPR023907 Non-F420 flavinoid oxidoreductase CNX65_RS18575 4d53a262f7a63b9e283d42de649f4159 319 Gene3D G3DSA:3.20.20.30 2 319 4.2E-52 T 28-03-2018 CNX65_RS34215 9ceb34d4eab64276f0e8bbf519002aad 276 PRINTS PR01217 Proline rich extensin signature 111 132 9.1E-9 T 28-03-2018 CNX65_RS34215 9ceb34d4eab64276f0e8bbf519002aad 276 PRINTS PR01217 Proline rich extensin signature 81 93 9.1E-9 T 28-03-2018 CNX65_RS34215 9ceb34d4eab64276f0e8bbf519002aad 276 PRINTS PR01217 Proline rich extensin signature 174 199 9.1E-9 T 28-03-2018 CNX65_RS34215 9ceb34d4eab64276f0e8bbf519002aad 276 PRINTS PR01217 Proline rich extensin signature 155 172 9.1E-9 T 28-03-2018 CNX65_RS34215 9ceb34d4eab64276f0e8bbf519002aad 276 PRINTS PR01217 Proline rich extensin signature 135 151 9.1E-9 T 28-03-2018 CNX65_RS21605 4e7a1f0e0bc48c1069cc138830887e20 230 Gene3D G3DSA:3.40.50.880 1 228 1.5E-48 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS21605 4e7a1f0e0bc48c1069cc138830887e20 230 SUPERFAMILY SSF52317 8 186 9.17E-44 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS21605 4e7a1f0e0bc48c1069cc138830887e20 230 Pfam PF01965 DJ-1/PfpI family 8 166 2.7E-23 T 28-03-2018 IPR002818 DJ-1/PfpI CNX65_RS14425 0299965266ca88a7ce412076d9593bee 186 Gene3D G3DSA:1.10.10.60 1 48 8.5E-17 T 28-03-2018 CNX65_RS14425 0299965266ca88a7ce412076d9593bee 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 1.6E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14425 0299965266ca88a7ce412076d9593bee 186 SUPERFAMILY SSF46689 4 75 1.08E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14425 0299965266ca88a7ce412076d9593bee 186 Gene3D G3DSA:1.10.10.60 49 177 2.6E-8 T 28-03-2018 CNX65_RS14425 0299965266ca88a7ce412076d9593bee 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14425 0299965266ca88a7ce412076d9593bee 186 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.9E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23155 ffec8ee9038efb1c4ebc1d69a63dbf95 266 Pfam PF00535 Glycosyl transferase family 2 5 116 9.7E-11 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS23155 ffec8ee9038efb1c4ebc1d69a63dbf95 266 Gene3D G3DSA:3.90.550.10 2 239 1.9E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS23155 ffec8ee9038efb1c4ebc1d69a63dbf95 266 SUPERFAMILY SSF53448 2 215 2.72E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS09855 947a7a6251aab40a171d321425eeb707 270 Gene3D G3DSA:3.40.50.150 13 270 1.5E-32 T 28-03-2018 CNX65_RS09855 947a7a6251aab40a171d321425eeb707 270 SUPERFAMILY SSF53335 30 211 9.15E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS09855 947a7a6251aab40a171d321425eeb707 270 Pfam PF08241 Methyltransferase domain 61 153 3.3E-17 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS28685 8fb26e213f0ee02ec354465a05b6a59c 117 SUPERFAMILY SSF54593 6 114 9.87E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS28685 8fb26e213f0ee02ec354465a05b6a59c 117 Gene3D G3DSA:3.10.180.10 2 117 6.1E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS05470 5293fe57622090323689f46d2fe79ed2 125 PIRSF PIRSF009151 1 124 1.4E-59 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CNX65_RS05470 5293fe57622090323689f46d2fe79ed2 125 Pfam PF05610 Protein of unknown function (DUF779) 14 111 4.8E-48 T 28-03-2018 IPR008497 Protein of unknown function DUF779 CNX65_RS04800 8a71d2bfdc123a170f11562622d41522 373 Pfam PF14072 DNA-sulfur modification-associated 16 363 5.9E-22 T 28-03-2018 IPR017642 DNA sulphur modification protein DndB CNX65_RS04800 8a71d2bfdc123a170f11562622d41522 373 TIGRFAM TIGR03187 DGQHR: DGQHR domain 7 305 8.5E-65 T 28-03-2018 IPR017601 DGQHR-containing domain CNX65_RS16645 7308724cadc976e9576116b9adfaaeda 208 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 9 186 6.5E-25 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS16645 7308724cadc976e9576116b9adfaaeda 208 Gene3D G3DSA:1.20.120.450 2 197 2.0E-13 T 28-03-2018 CNX65_RS16645 7308724cadc976e9576116b9adfaaeda 208 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 9 92 5.3E-9 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS16645 7308724cadc976e9576116b9adfaaeda 208 SUPERFAMILY SSF109854 3 123 1.51E-11 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS07120 5af9a1f83eef1b72f4c825335c687916 162 SUPERFAMILY SSF46785 12 138 1.36E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07120 5af9a1f83eef1b72f4c825335c687916 162 Pfam PF12840 Helix-turn-helix domain 11 61 4.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS07120 5af9a1f83eef1b72f4c825335c687916 162 Gene3D G3DSA:1.10.10.10 3 152 7.8E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02650 3ea26097839845f7aa4f8b7eabb1fa70 448 Pfam PF13520 Amino acid permease 10 403 2.4E-40 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS02650 3ea26097839845f7aa4f8b7eabb1fa70 448 PIRSF PIRSF006060 1 440 3.3E-71 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS06245 aa8ccf16872922ff3e42b466bb62d4e5 113 Gene3D G3DSA:3.40.30.10 1 109 6.3E-5 T 28-03-2018 CNX65_RS24350 8c47491d9844d342524b8a7608afeca4 292 Gene3D G3DSA:3.40.50.1820 10 291 1.4E-26 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24350 8c47491d9844d342524b8a7608afeca4 292 SUPERFAMILY SSF53474 7 290 6.89E-30 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24350 8c47491d9844d342524b8a7608afeca4 292 Pfam PF12697 Alpha/beta hydrolase family 21 286 6.2E-21 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS30860 bfb6a0d7020a30cb7f86c54bfc99a82c 294 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 36 290 1.5E-39 T 28-03-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0005215|GO:0006810 CNX65_RS30860 bfb6a0d7020a30cb7f86c54bfc99a82c 294 Gene3D G3DSA:3.40.190.10 174 294 4.1E-14 T 28-03-2018 CNX65_RS30860 bfb6a0d7020a30cb7f86c54bfc99a82c 294 Gene3D G3DSA:3.40.190.10 25 173 8.7E-28 T 28-03-2018 CNX65_RS30860 bfb6a0d7020a30cb7f86c54bfc99a82c 294 SUPERFAMILY SSF53850 36 291 3.26E-41 T 28-03-2018 CNX65_RS13030 f606785ed469e39be0ed66c94160685f 427 Gene3D G3DSA:3.40.50.150 266 426 2.3E-27 T 28-03-2018 CNX65_RS13030 f606785ed469e39be0ed66c94160685f 427 Pfam PF05401 Nodulation protein S (NodS) 258 380 2.1E-14 T 28-03-2018 IPR008715 SAM-dependent methyltransferase, NodS-related GO:0008757|GO:0009312|GO:0009877 CNX65_RS13030 f606785ed469e39be0ed66c94160685f 427 SUPERFAMILY SSF102588 30 216 4.32E-42 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS13030 f606785ed469e39be0ed66c94160685f 427 Gene3D G3DSA:3.40.50.10320 16 259 2.1E-39 T 28-03-2018 IPR024078 Putative deacetylase LmbE-like domain Reactome: R-HSA-162710 CNX65_RS13030 f606785ed469e39be0ed66c94160685f 427 Pfam PF02585 GlcNAc-PI de-N-acetylase 33 157 1.9E-25 T 28-03-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 CNX65_RS13030 f606785ed469e39be0ed66c94160685f 427 SUPERFAMILY SSF53335 253 403 3.8E-22 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS15925 388ce484c4a500cf9c4df539c96c96ae 374 Pfam PF06722 Protein of unknown function (DUF1205) 171 259 1.9E-19 T 28-03-2018 IPR010610 Domain of unknown function DUF1205 CNX65_RS15925 388ce484c4a500cf9c4df539c96c96ae 374 Gene3D G3DSA:3.40.50.2000 198 358 7.7E-31 T 28-03-2018 CNX65_RS15925 388ce484c4a500cf9c4df539c96c96ae 374 Gene3D G3DSA:3.40.50.2000 1 197 6.2E-38 T 28-03-2018 CNX65_RS15925 388ce484c4a500cf9c4df539c96c96ae 374 SUPERFAMILY SSF53756 1 373 6.06E-71 T 28-03-2018 CNX65_RS16135 acabb7c7bc8bfce2fb1a3fd5ec9534b9 384 PIRSF PIRSF005739 35 371 2.5E-35 T 28-03-2018 IPR016461 O-methyltransferase COMT-type GO:0008168 CNX65_RS16135 acabb7c7bc8bfce2fb1a3fd5ec9534b9 384 SUPERFAMILY SSF46785 50 134 7.35E-13 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16135 acabb7c7bc8bfce2fb1a3fd5ec9534b9 384 Gene3D G3DSA:1.10.10.10 45 132 3.0E-12 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16135 acabb7c7bc8bfce2fb1a3fd5ec9534b9 384 SUPERFAMILY SSF53335 149 373 3.98E-42 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS16135 acabb7c7bc8bfce2fb1a3fd5ec9534b9 384 Pfam PF00891 O-methyltransferase 151 357 4.0E-37 T 28-03-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 CNX65_RS16135 acabb7c7bc8bfce2fb1a3fd5ec9534b9 384 Gene3D G3DSA:3.40.50.150 133 377 3.7E-34 T 28-03-2018 CNX65_RS22890 237b517399122091164ee736e20182bc 286 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS22890 237b517399122091164ee736e20182bc 286 Pfam PF00005 ABC transporter 19 172 7.1E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS22890 237b517399122091164ee736e20182bc 286 Gene3D G3DSA:3.40.50.300 1 264 4.7E-64 T 28-03-2018 CNX65_RS22890 237b517399122091164ee736e20182bc 286 SUPERFAMILY SSF52540 1 236 2.0E-58 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS22890 237b517399122091164ee736e20182bc 286 SMART SM00382 28 220 3.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS16650 462967cbdc74ffc8a9af2032ef9caeed 253 Pfam PF13936 Helix-turn-helix domain 5 45 4.9E-14 T 28-03-2018 IPR025246 Transposase IS30-like HTH domain CNX65_RS16650 462967cbdc74ffc8a9af2032ef9caeed 253 SUPERFAMILY SSF46785 87 170 3.0E-14 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16650 462967cbdc74ffc8a9af2032ef9caeed 253 Gene3D G3DSA:1.10.10.60 3 47 9.6E-10 T 28-03-2018 CNX65_RS16650 462967cbdc74ffc8a9af2032ef9caeed 253 Pfam PF12802 MarR family 104 162 3.5E-11 T 28-03-2018 CNX65_RS16650 462967cbdc74ffc8a9af2032ef9caeed 253 Gene3D G3DSA:1.10.10.10 48 241 3.9E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS05635 5e3501f273b7d694b8c16de7e3348000 146 Pfam PF13279 Thioesterase-like superfamily 11 122 1.5E-11 T 28-03-2018 CNX65_RS05635 5e3501f273b7d694b8c16de7e3348000 146 SUPERFAMILY SSF54637 4 136 8.72E-29 T 28-03-2018 IPR029069 HotDog domain CNX65_RS05635 5e3501f273b7d694b8c16de7e3348000 146 Gene3D G3DSA:3.10.129.10 2 139 1.4E-28 T 28-03-2018 CNX65_RS06285 de3f8d335657da8113b4b18cde72c382 141 Gene3D G3DSA:1.10.10.10 10 90 4.8E-23 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06285 de3f8d335657da8113b4b18cde72c382 141 SUPERFAMILY SSF46785 13 135 2.49E-37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS06285 de3f8d335657da8113b4b18cde72c382 141 Pfam PF01475 Ferric uptake regulator family 13 129 2.9E-36 T 28-03-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 339 348 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 192 214 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 289 316 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 154 169 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 269 280 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 90 101 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 337 346 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 346 357 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00359 B-class P450 signature 137 153 9.0E-33 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 Pfam PF00067 Cytochrome P450 199 367 2.7E-16 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 Gene3D G3DSA:1.10.630.10 20 397 8.9E-63 T 28-03-2018 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00385 P450 superfamily signature 337 346 1.8E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00385 P450 superfamily signature 234 251 1.8E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00385 P450 superfamily signature 269 280 1.8E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 PRINTS PR00385 P450 superfamily signature 346 357 1.8E-6 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS18490 22f92361470aeaf86696abf84dbf1856 397 SUPERFAMILY SSF48264 30 397 2.49E-79 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS10565 19e8755cd220db69dc7169c4b96926bf 122 Pfam PF05331 Protein of unknown function (DUF742) 12 120 1.5E-33 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CNX65_RS10565 19e8755cd220db69dc7169c4b96926bf 122 Gene3D G3DSA:1.10.10.10 45 115 2.4E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS01530 4960f9fc7beb7f17b714b9cbf3b7d796 677 SUPERFAMILY SSF81345 349 671 5.1E-72 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS01530 4960f9fc7beb7f17b714b9cbf3b7d796 677 SUPERFAMILY SSF81345 3 329 8.63E-58 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS01530 4960f9fc7beb7f17b714b9cbf3b7d796 677 Pfam PF01032 FecCD transport family 365 671 1.5E-80 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS01530 4960f9fc7beb7f17b714b9cbf3b7d796 677 Pfam PF01032 FecCD transport family 15 329 8.3E-68 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS01530 4960f9fc7beb7f17b714b9cbf3b7d796 677 Gene3D G3DSA:1.10.3470.10 1 337 5.3E-51 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS01530 4960f9fc7beb7f17b714b9cbf3b7d796 677 Gene3D G3DSA:1.10.3470.10 348 677 1.9E-65 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS29290 54400f27dbe669b4284a4040b536f8f1 60 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 57 6.5E-20 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29290 54400f27dbe669b4284a4040b536f8f1 60 Pfam PF01783 Ribosomal L32p protein family 2 58 5.2E-22 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29290 54400f27dbe669b4284a4040b536f8f1 60 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 2 57 16.766 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS29290 54400f27dbe669b4284a4040b536f8f1 60 SUPERFAMILY SSF57829 2 57 8.55E-17 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CNX65_RS26670 9e7eff4af14ccf7caca2b906884afe1d 150 Pfam PF00498 FHA domain 72 134 5.0E-20 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CNX65_RS26670 9e7eff4af14ccf7caca2b906884afe1d 150 SMART SM00240 70 120 2.8E-17 T 28-03-2018 IPR000253 Forkhead-associated (FHA) domain GO:0005515 CNX65_RS26670 9e7eff4af14ccf7caca2b906884afe1d 150 Gene3D G3DSA:2.60.200.20 24 143 1.0E-30 T 28-03-2018 CNX65_RS26670 9e7eff4af14ccf7caca2b906884afe1d 150 SUPERFAMILY SSF49879 24 141 4.02E-33 T 28-03-2018 IPR008984 SMAD/FHA domain GO:0005515 CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 126 134 5.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 5.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 157 176 5.9E-6 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 SUPERFAMILY SSF51735 4 232 4.2E-53 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 Gene3D G3DSA:3.40.50.720 1 236 3.2E-55 T 28-03-2018 CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 Pfam PF00106 short chain dehydrogenase 5 197 1.6E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 157 176 2.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 120 136 2.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 2.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12165 26f4c29a7d2b1801fee8afb31e17182a 236 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 177 194 2.6E-21 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS21915 eb938f6c1f96d86fe86212202bd471a7 774 SUPERFAMILY SSF158682 467 594 3.66E-21 T 28-03-2018 CNX65_RS21915 eb938f6c1f96d86fe86212202bd471a7 774 Pfam PF13208 TerB N-terminal domain 71 276 7.3E-58 T 28-03-2018 IPR025266 TerB, N-terminal CNX65_RS21915 eb938f6c1f96d86fe86212202bd471a7 774 Gene3D G3DSA:1.10.3680.10 460 597 1.9E-17 T 28-03-2018 IPR029024 TerB-like CNX65_RS21915 eb938f6c1f96d86fe86212202bd471a7 774 Pfam PF05099 Tellurite resistance protein TerB 471 587 6.1E-13 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal CNX65_RS21915 eb938f6c1f96d86fe86212202bd471a7 774 Pfam PF15615 TerB-C domain 650 767 4.8E-22 T 28-03-2018 IPR028932 TerB-C domain CNX65_RS01135 67261fa230b7833d51493ee29c20986b 51 Pfam PF13783 Domain of unknown function (DUF4177) 4 39 1.7E-6 T 28-03-2018 IPR025234 Protein of unknown function DUF4177 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 Gene3D G3DSA:3.40.50.1980 389 509 7.1E-29 T 28-03-2018 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 Pfam PF01297 Zinc-uptake complex component A periplasmic 37 507 7.3E-78 T 28-03-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 PRINTS PR00690 Adhesin family signature 34 52 1.0E-11 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 PRINTS PR00690 Adhesin family signature 65 78 1.0E-11 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 PRINTS PR00690 Adhesin family signature 78 95 1.0E-11 T 28-03-2018 IPR006128 Adhesion lipoprotein GO:0007155 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 TIGRFAM TIGR03772 anch_rpt_subst: anchored repeat ABC transporter, substrate-binding protein 37 509 3.3E-195 T 28-03-2018 IPR022434 ABC transporter, LPXTG-anchor lipoprotein, actinobacteria CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 TIGRFAM TIGR03769 P_ac_wall_RPT: actinobacterial surface-anchored protein domain 206 247 5.5E-13 T 28-03-2018 IPR022435 Surface-anchored repeat, actinobacteria CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 Gene3D G3DSA:3.40.50.1980 36 388 2.6E-50 T 28-03-2018 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 SUPERFAMILY SSF53807 32 125 5.49E-67 T 28-03-2018 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 SUPERFAMILY SSF53807 331 509 5.49E-67 T 28-03-2018 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 PRINTS PR00691 Adhesin B signature 59 77 2.7E-13 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 PRINTS PR00691 Adhesin B signature 34 55 2.7E-13 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CNX65_RS23675 3a93db6f9a5a8ea317ecd03fac26452b 509 PRINTS PR00691 Adhesin B signature 78 97 2.7E-13 T 28-03-2018 IPR006129 Adhesin B GO:0007155 CNX65_RS22215 3556a53d637e7f0881837a70c9850d1f 277 Gene3D G3DSA:3.40.50.1820 1 277 4.0E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22215 3556a53d637e7f0881837a70c9850d1f 277 Pfam PF12697 Alpha/beta hydrolase family 24 266 6.4E-22 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS22215 3556a53d637e7f0881837a70c9850d1f 277 SUPERFAMILY SSF53474 3 273 2.34E-51 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22215 3556a53d637e7f0881837a70c9850d1f 277 PRINTS PR00412 Epoxide hydrolase signature 28 46 3.9E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS22215 3556a53d637e7f0881837a70c9850d1f 277 PRINTS PR00412 Epoxide hydrolase signature 105 118 3.9E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS22215 3556a53d637e7f0881837a70c9850d1f 277 PRINTS PR00412 Epoxide hydrolase signature 249 271 3.9E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS22215 3556a53d637e7f0881837a70c9850d1f 277 PRINTS PR00412 Epoxide hydrolase signature 48 63 3.9E-9 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS23725 71b7f34932d87f7836a0334bee676555 243 SUPERFAMILY SSF53335 36 217 9.1E-21 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS23725 71b7f34932d87f7836a0334bee676555 243 Gene3D G3DSA:3.40.50.150 33 224 3.3E-15 T 28-03-2018 CNX65_RS00410 c1ecb37ac9190773c585cc7218d57846 343 Pfam PF13816 Haem-containing dehydratase 41 337 1.7E-71 T 28-03-2018 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7|MetaCyc: PWY-7824 CNX65_RS00410 c1ecb37ac9190773c585cc7218d57846 343 SUPERFAMILY SSF54909 38 109 2.44E-5 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS00410 c1ecb37ac9190773c585cc7218d57846 343 Gene3D G3DSA:3.30.70.100 34 127 1.5E-5 T 28-03-2018 CNX65_RS00410 c1ecb37ac9190773c585cc7218d57846 343 ProDom PD320837 DEHYDRATASE PHENYLACETALDOXIME ALDOXIME LYASE METAL-BINDING IRON HEME TRUNCATION DIRECT 4.2.1.- 15 338 3.0E-43 T 28-03-2018 IPR025702 Haem-containing dehydratase KEGG: 00460+4.99.1.7|KEGG: 00643+4.99.1.7|MetaCyc: PWY-7824 CNX65_RS33860 d7a4db7b6e24fbc2388943757e7f5db6 345 Gene3D G3DSA:1.10.3470.10 38 336 1.1E-24 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS33860 d7a4db7b6e24fbc2388943757e7f5db6 345 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 330 3.3E-56 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS22635 581014bc8a2e55b2ee691ef7c4745d8f 439 Gene3D G3DSA:3.90.79.10 233 391 1.0E-4 T 28-03-2018 CNX65_RS29165 a69751aef0f39cf9e1cb89210befa4cc 401 SUPERFAMILY SSF51621 87 321 4.16E-18 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS29165 a69751aef0f39cf9e1cb89210befa4cc 401 Gene3D G3DSA:3.20.20.360 73 360 7.3E-33 T 28-03-2018 CNX65_RS30185 76814c238e9887e03660b4e40b5290d8 143 Pfam PF10739 Protein of unknown function (DUF2550) 11 136 5.3E-46 T 28-03-2018 IPR019675 Protein of unknown function DUF2550 CNX65_RS24755 4fa703f62e1f88ea617fdbb71ec8d20f 346 SUPERFAMILY SSF48576 32 344 2.72E-72 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS24755 4fa703f62e1f88ea617fdbb71ec8d20f 346 Gene3D G3DSA:1.10.600.10 3 346 2.0E-89 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS24755 4fa703f62e1f88ea617fdbb71ec8d20f 346 Pfam PF00348 Polyprenyl synthetase 61 282 4.8E-53 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CNX65_RS24755 4fa703f62e1f88ea617fdbb71ec8d20f 346 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 99 113 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CNX65_RS20130 186df1d4d75d2fe44afa12e8ac71dc3e 404 SUPERFAMILY SSF51445 136 402 1.16E-64 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS20130 186df1d4d75d2fe44afa12e8ac71dc3e 404 Pfam PF00933 Glycosyl hydrolase family 3 N terminal domain 90 399 8.5E-72 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS20130 186df1d4d75d2fe44afa12e8ac71dc3e 404 Gene3D G3DSA:3.20.20.300 69 403 5.2E-62 T 28-03-2018 IPR001764 Glycoside hydrolase, family 3, N-terminal GO:0004553|GO:0005975 CNX65_RS20130 186df1d4d75d2fe44afa12e8ac71dc3e 404 ProSitePatterns PS00775 Glycosyl hydrolases family 3 active site. 318 335 - T 28-03-2018 IPR019800 Glycoside hydrolase, family 3, active site GO:0004553|GO:0005975 CNX65_RS00690 73fb0d5ccf693cd9c74efcec6f6e258e 217 SUPERFAMILY SSF53335 54 199 4.74E-11 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS00690 73fb0d5ccf693cd9c74efcec6f6e258e 217 Pfam PF13578 Methyltransferase domain 58 182 4.0E-18 T 28-03-2018 CNX65_RS00690 73fb0d5ccf693cd9c74efcec6f6e258e 217 Gene3D G3DSA:3.40.50.150 30 213 3.6E-18 T 28-03-2018 CNX65_RS07430 39e19d4b47a690bbcf6de62835774432 81 Pfam PF11238 Protein of unknown function (DUF3039) 21 76 4.9E-29 T 28-03-2018 IPR021400 Protein of unknown function DUF3039 CNX65_RS18045 2a31146dea4dadfad1b67083aeba9a64 307 Pfam PF01636 Phosphotransferase enzyme family 31 247 7.2E-13 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS18045 2a31146dea4dadfad1b67083aeba9a64 307 Gene3D G3DSA:3.30.200.20 4 116 2.7E-4 T 28-03-2018 CNX65_RS18045 2a31146dea4dadfad1b67083aeba9a64 307 SUPERFAMILY SSF56112 4 257 7.48E-22 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS18045 2a31146dea4dadfad1b67083aeba9a64 307 Gene3D G3DSA:3.90.1200.10 123 306 4.9E-12 T 28-03-2018 CNX65_RS02155 67f552fb53b83a19bdccf677fa6fbcff 547 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 85 512 55.934 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CNX65_RS02155 67f552fb53b83a19bdccf677fa6fbcff 547 Pfam PF13667 ThiC-associated domain 18 80 3.6E-11 T 28-03-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CNX65_RS02155 67f552fb53b83a19bdccf677fa6fbcff 547 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 86 509 1.1E-205 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CNX65_RS02155 67f552fb53b83a19bdccf677fa6fbcff 547 Pfam PF01964 Radical SAM ThiC family 86 506 3.3E-198 T 28-03-2018 IPR002817 Phosphomethylpyrimidine synthase GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 CNX65_RS05050 f34072d6c44aa60aa2ea3044c27e1924 204 SUPERFAMILY SSF56266 16 193 4.18E-11 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS05050 f34072d6c44aa60aa2ea3044c27e1924 204 Gene3D G3DSA:3.60.70.12 135 204 0.0074 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS05050 f34072d6c44aa60aa2ea3044c27e1924 204 Gene3D G3DSA:3.60.70.12 11 134 6.9E-21 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS00470 b0663778b0fb614d54a065e25d1ce585 334 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 211 4.3E-62 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CNX65_RS00470 b0663778b0fb614d54a065e25d1ce585 334 PIRSF PIRSF000267 1 330 8.6E-101 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CNX65_RS00470 b0663778b0fb614d54a065e25d1ce585 334 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 2 318 6.0E-99 T 28-03-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 Gene3D G3DSA:3.90.226.10 11 204 7.9E-37 T 28-03-2018 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 121 134 - T 28-03-2018 IPR033135 ClpP, histidine active site CNX65_RS05750 faab984164fa56996ff37052815a863a 209 Pfam PF00574 Clp protease 27 200 1.1E-73 T 28-03-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA CNX65_RS05750 faab984164fa56996ff37052815a863a 209 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 99 110 - T 28-03-2018 IPR018215 ClpP, Ser active site CNX65_RS05750 faab984164fa56996ff37052815a863a 209 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 12 203 38.768 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 PRINTS PR00127 Clp protease catalytic subunit P signature 99 116 2.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 PRINTS PR00127 Clp protease catalytic subunit P signature 120 139 2.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 PRINTS PR00127 Clp protease catalytic subunit P signature 68 88 2.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 PRINTS PR00127 Clp protease catalytic subunit P signature 28 43 2.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 PRINTS PR00127 Clp protease catalytic subunit P signature 178 197 2.0E-41 T 28-03-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 CNX65_RS05750 faab984164fa56996ff37052815a863a 209 SUPERFAMILY SSF52096 20 204 3.98E-61 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS10955 8e00753634e809aab56411a631137fb0 321 Pfam PF07584 Aerotolerance regulator N-terminal 5 78 1.6E-5 T 28-03-2018 IPR024163 Aerotolerance regulator, N-terminal CNX65_RS10955 8e00753634e809aab56411a631137fb0 321 Pfam PF00092 von Willebrand factor type A domain 91 279 2.7E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS10955 8e00753634e809aab56411a631137fb0 321 SMART SM00327 88 286 2.8E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS10955 8e00753634e809aab56411a631137fb0 321 SUPERFAMILY SSF53300 85 283 3.53E-31 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS10955 8e00753634e809aab56411a631137fb0 321 Gene3D G3DSA:3.40.50.410 83 296 4.2E-43 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS15095 ff03c1a142453b8d17e1fcd6aab605d3 240 SUPERFAMILY SSF53474 37 227 8.19E-45 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS15095 ff03c1a142453b8d17e1fcd6aab605d3 240 Gene3D G3DSA:3.40.50.1820 26 232 9.7E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS15095 ff03c1a142453b8d17e1fcd6aab605d3 240 Pfam PF00561 alpha/beta hydrolase fold 62 150 1.1E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS11520 fb559218349ed909a3ce4cb59c2c4a42 1098 SUPERFAMILY SSF48452 768 939 7.27E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11520 fb559218349ed909a3ce4cb59c2c4a42 1098 Gene3D G3DSA:1.25.40.10 838 1006 1.2E-12 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS11520 fb559218349ed909a3ce4cb59c2c4a42 1098 Gene3D G3DSA:1.25.40.10 541 830 6.8E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS29205 5df28aec7adc0ad0234f949ec2f098cd 141 SUPERFAMILY SSF55729 15 132 8.51E-14 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS29205 5df28aec7adc0ad0234f949ec2f098cd 141 Gene3D G3DSA:3.40.630.30 7 140 1.8E-15 T 28-03-2018 CNX65_RS29205 5df28aec7adc0ad0234f949ec2f098cd 141 Pfam PF00583 Acetyltransferase (GNAT) family 40 126 2.2E-11 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS02825 bbbb51cd665fdd4a11f1dbca84890adb 111 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 1 102 6.4E-18 T 28-03-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like CNX65_RS02825 bbbb51cd665fdd4a11f1dbca84890adb 111 Gene3D G3DSA:3.10.490.10 1 110 4.5E-19 T 28-03-2018 CNX65_RS02825 bbbb51cd665fdd4a11f1dbca84890adb 111 SUPERFAMILY SSF110857 1 109 5.62E-20 T 28-03-2018 IPR013024 Gamma-glutamyl cyclotransferase-like CNX65_RS29690 d6d3d853899bca31b971bde1eff8b53b 215 Gene3D G3DSA:3.30.70.260 1 75 1.1E-9 T 28-03-2018 CNX65_RS29690 d6d3d853899bca31b971bde1eff8b53b 215 SUPERFAMILY SSF55021 3 70 7.91E-8 T 28-03-2018 CNX65_RS23120 ed808d0273f5f7e4841ddfc66e954c9b 137 Pfam PF10901 Protein of unknown function (DUF2690) 35 113 1.4E-5 T 28-03-2018 IPR021224 Protein of unknown function DUF2690 CNX65_RS04040 5c9359614ba41ae12547efbaa78f1521 186 Pfam PF03703 Bacterial PH domain 81 155 3.5E-14 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CNX65_RS07770 513510d5a0a1b1af8dfb9ec582f54f97 142 Pfam PF01641 SelR domain 17 136 3.6E-50 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CNX65_RS07770 513510d5a0a1b1af8dfb9ec582f54f97 142 SUPERFAMILY SSF51316 13 139 6.28E-52 T 28-03-2018 IPR011057 Mss4-like CNX65_RS07770 513510d5a0a1b1af8dfb9ec582f54f97 142 Gene3D G3DSA:2.170.150.20 4 142 3.1E-53 T 28-03-2018 CNX65_RS07770 513510d5a0a1b1af8dfb9ec582f54f97 142 TIGRFAM TIGR00357 TIGR00357: methionine-R-sulfoxide reductase 14 139 4.7E-46 T 28-03-2018 IPR002579 Peptide methionine sulphoxide reductase MrsB GO:0033743|GO:0055114 Reactome: R-HSA-5676934 CNX65_RS15885 5ba61cbf37d70ee3e490a0db206210d1 459 Gene3D G3DSA:3.40.109.10 27 189 4.5E-11 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS15885 5ba61cbf37d70ee3e490a0db206210d1 459 Gene3D G3DSA:3.40.109.10 227 439 8.0E-19 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS15885 5ba61cbf37d70ee3e490a0db206210d1 459 SUPERFAMILY SSF55469 58 180 5.71E-6 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS15885 5ba61cbf37d70ee3e490a0db206210d1 459 Pfam PF00881 Nitroreductase family 271 437 8.9E-9 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS15885 5ba61cbf37d70ee3e490a0db206210d1 459 SUPERFAMILY SSF55469 340 447 4.61E-10 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS15885 5ba61cbf37d70ee3e490a0db206210d1 459 SUPERFAMILY SSF55469 270 296 4.61E-10 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS02375 02c7faf28f24f2a6451a8bd23e3cfad6 141 Gene3D G3DSA:3.90.1170.40 3 140 1.7E-44 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS02375 02c7faf28f24f2a6451a8bd23e3cfad6 141 SUPERFAMILY SSF54690 8 139 4.84E-37 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS02375 02c7faf28f24f2a6451a8bd23e3cfad6 141 Pfam PF02391 MoaE protein 9 121 3.4E-34 T 28-03-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|Reactome: R-HSA-947581 CNX65_RS33750 7daf15ad4ff6ed015a3025dc82245161 268 Pfam PF11209 Protein of unknown function (DUF2993) 28 259 1.2E-41 T 28-03-2018 IPR021373 Protein of unknown function DUF2993 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 Pfam PF02637 GatB domain 352 496 8.4E-38 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 SUPERFAMILY SSF55931 19 321 2.09E-109 T 28-03-2018 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 Pfam PF02934 GatB/GatE catalytic domain 20 314 8.4E-103 T 28-03-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 16 495 3.2E-139 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 SMART SM00845 352 499 3.7E-53 T 28-03-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 16 500 35.152 T 28-03-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 SUPERFAMILY SSF89095 351 497 5.36E-27 T 28-03-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-related GO:0016884 CNX65_RS29670 69e76bc55226e48ab3aac92873ef9292 501 Gene3D G3DSA:1.10.10.410 439 498 3.8E-16 T 28-03-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal CNX65_RS20790 2f72f96f806c8aadfa82a69ca5355387 256 Pfam PF01609 Transposase DDE domain 98 240 1.0E-14 T 28-03-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 CNX65_RS20790 2f72f96f806c8aadfa82a69ca5355387 256 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 1 77 5.1E-25 T 28-03-2018 IPR025161 Putative transposase IS4/IS5 family CNX65_RS08240 8a86d3b3d752f0387e48ba8e8a09d596 361 Gene3D G3DSA:3.40.710.10 5 361 4.6E-57 T 28-03-2018 CNX65_RS08240 8a86d3b3d752f0387e48ba8e8a09d596 361 Pfam PF00144 Beta-lactamase 16 342 3.6E-41 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS08240 8a86d3b3d752f0387e48ba8e8a09d596 361 SUPERFAMILY SSF56601 10 356 2.16E-56 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS14835 1b42f097d8991aa89e304d8be03f7c01 103 Pfam PF05488 PAAR motif 8 90 4.1E-19 T 28-03-2018 IPR008727 PAAR motif CNX65_RS03240 0bed930ecc85ce6288ce0b1de491a505 160 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 119 155 8.3E-9 T 28-03-2018 IPR019933 DivIVA domain CNX65_RS03240 0bed930ecc85ce6288ce0b1de491a505 160 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 36 63 7.0E-6 T 28-03-2018 IPR019933 DivIVA domain CNX65_RS03240 0bed930ecc85ce6288ce0b1de491a505 160 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 1 30 2.9E-10 T 28-03-2018 IPR019933 DivIVA domain CNX65_RS26170 c80ac005d64a4c4525cea3964ebd0b5c 78 Gene3D G3DSA:3.30.1360.60 3 78 2.7E-28 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CNX65_RS26170 c80ac005d64a4c4525cea3964ebd0b5c 78 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 3 64 1.1E-18 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CNX65_RS26170 c80ac005d64a4c4525cea3964ebd0b5c 78 Pfam PF00367 phosphotransferase system, EIIB 9 40 7.1E-14 T 28-03-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 CNX65_RS26170 c80ac005d64a4c4525cea3964ebd0b5c 78 SUPERFAMILY SSF55604 5 77 1.44E-21 T 28-03-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 CNX65_RS02675 3b37930ed531713f33ccb8f120dcf935 312 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 246 259 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS02675 3b37930ed531713f33ccb8f120dcf935 312 Gene3D G3DSA:3.40.1190.20 1 312 1.6E-59 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS02675 3b37930ed531713f33ccb8f120dcf935 312 Pfam PF00294 pfkB family carbohydrate kinase 2 303 1.3E-43 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS02675 3b37930ed531713f33ccb8f120dcf935 312 SUPERFAMILY SSF53613 2 305 7.33E-65 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS02620 31ca2125606dd95e4175ae369299c04c 271 Pfam PF11268 Protein of unknown function (DUF3071) 1 169 9.2E-62 T 28-03-2018 IPR021421 Protein of unknown function DUF3071 CNX65_RS11555 6569474cd42858524fef2fc4f670f0cf 180 Pfam PF04264 YceI-like domain 14 175 2.7E-48 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CNX65_RS11555 6569474cd42858524fef2fc4f670f0cf 180 Gene3D G3DSA:2.40.128.110 9 180 1.3E-56 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CNX65_RS11555 6569474cd42858524fef2fc4f670f0cf 180 SUPERFAMILY SSF101874 12 179 6.41E-54 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CNX65_RS11555 6569474cd42858524fef2fc4f670f0cf 180 SMART SM00867 13 177 8.5E-63 T 28-03-2018 IPR007372 Lipid/polyisoprenoid-binding, YceI-like CNX65_RS24305 ac8489706c793271e38c3f5897e84249 387 Gene3D G3DSA:1.10.20.10 172 284 4.4E-4 T 28-03-2018 CNX65_RS24305 ac8489706c793271e38c3f5897e84249 387 SMART SM00530 14 76 0.0041 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS24305 ac8489706c793271e38c3f5897e84249 387 SUPERFAMILY SSF52540 104 315 3.33E-19 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24305 ac8489706c793271e38c3f5897e84249 387 Gene3D G3DSA:3.40.50.300 87 171 1.2E-4 T 28-03-2018 CNX65_RS24305 ac8489706c793271e38c3f5897e84249 387 Gene3D G3DSA:1.10.260.40 5 81 2.2E-6 T 28-03-2018 CNX65_RS29115 5667168f9eb3d340c0f92a8c1cc89aeb 182 Pfam PF13671 AAA domain 14 156 1.3E-10 T 28-03-2018 CNX65_RS29115 5667168f9eb3d340c0f92a8c1cc89aeb 182 Gene3D G3DSA:3.40.50.300 25 177 1.2E-14 T 28-03-2018 CNX65_RS29115 5667168f9eb3d340c0f92a8c1cc89aeb 182 SUPERFAMILY SSF52540 13 150 1.03E-10 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS29115 5667168f9eb3d340c0f92a8c1cc89aeb 182 Gene3D G3DSA:3.40.50.300 1 24 0.0038 T 28-03-2018 CNX65_RS18305 b72068ca6a2e4e989ec3c41e56fae6c8 300 Gene3D G3DSA:3.40.50.150 3 295 2.9E-7 T 28-03-2018 CNX65_RS18305 b72068ca6a2e4e989ec3c41e56fae6c8 300 SUPERFAMILY SSF53335 6 137 3.33E-6 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 SUPERFAMILY SSF51905 7 237 2.67E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 SUPERFAMILY SSF51905 199 424 2.09E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 201 219 3.0E-5 T 28-03-2018 CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 160 178 3.0E-5 T 28-03-2018 CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.0E-5 T 28-03-2018 CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 Gene3D G3DSA:3.50.50.60 1 210 4.7E-12 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 6 348 5.0E-111 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CNX65_RS24940 184e97941bac83f27f9b86ae0cde2a7f 442 Gene3D G3DSA:3.50.50.60 211 431 3.7E-18 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS23885 5a4ff27e5967adf23b65cc95c8457479 298 Gene3D G3DSA:3.40.50.720 1 297 2.1E-17 T 28-03-2018 CNX65_RS23885 5a4ff27e5967adf23b65cc95c8457479 298 SUPERFAMILY SSF51735 1 269 2.11E-25 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23885 5a4ff27e5967adf23b65cc95c8457479 298 Pfam PF13460 NAD(P)H-binding 7 155 3.0E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS02150 1897483f642964389b671d1aba1439ac 276 Pfam PF08543 Phosphomethylpyrimidine kinase 20 268 6.5E-80 T 28-03-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 CNX65_RS02150 1897483f642964389b671d1aba1439ac 276 Gene3D G3DSA:3.40.1190.20 7 264 1.6E-59 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS02150 1897483f642964389b671d1aba1439ac 276 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 13 269 2.5E-82 T 28-03-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 CNX65_RS02150 1897483f642964389b671d1aba1439ac 276 SUPERFAMILY SSF53613 9 272 1.45E-76 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS07815 b4d9dcf97ab0cf9fd52705ea8ad1e674 220 Gene3D G3DSA:1.10.10.10 34 218 0.0031 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02840 940ac909ccc9aafe87adae0e0f077a44 603 SUPERFAMILY SSF52540 20 234 2.36E-28 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02840 940ac909ccc9aafe87adae0e0f077a44 603 Gene3D G3DSA:3.40.50.300 20 550 1.2E-35 T 28-03-2018 CNX65_RS02840 940ac909ccc9aafe87adae0e0f077a44 603 Pfam PF00350 Dynamin family 42 199 2.9E-15 T 28-03-2018 IPR022812 Dynamin superfamily CNX65_RS32745 c8dc80fffc1e0168216dcfe731bea4d5 147 SUPERFAMILY SSF140990 11 143 1.19E-9 T 28-03-2018 CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 Pfam PF05239 PRC-barrel domain 95 169 6.0E-11 T 28-03-2018 IPR027275 PRC-barrel domain CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 Gene3D G3DSA:2.40.30.60 2 92 2.7E-24 T 28-03-2018 IPR002676 RimM protein GO:0006364 CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 SUPERFAMILY SSF50346 98 168 1.16E-15 T 28-03-2018 IPR011033 PRC-barrel-like CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 3 168 2.9E-38 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 SUPERFAMILY SSF50447 3 90 8.95E-18 T 28-03-2018 IPR009000 Translation protein, beta-barrel domain CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 Gene3D G3DSA:2.30.30.240 94 163 1.4E-20 T 28-03-2018 CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 Pfam PF01782 RimM N-terminal domain 4 83 3.7E-21 T 28-03-2018 IPR002676 RimM protein GO:0006364 CNX65_RS29070 fc198730506210cba6d883bd1d9c3e41 172 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 2 168 22.67 T 28-03-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 CNX65_RS08810 a1880c112e9895b1aad87b33089f1044 447 Gene3D G3DSA:1.20.5.1230 257 424 7.6E-8 T 28-03-2018 CNX65_RS08810 a1880c112e9895b1aad87b33089f1044 447 Gene3D G3DSA:1.20.120.20 3 256 0.12 T 28-03-2018 CNX65_RS14590 b5e99dab53e7b59bfe060c747b3e0f48 236 SUPERFAMILY SSF46689 12 93 4.77E-13 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14590 b5e99dab53e7b59bfe060c747b3e0f48 236 Gene3D G3DSA:1.10.357.10 3 232 1.8E-31 T 28-03-2018 CNX65_RS14590 b5e99dab53e7b59bfe060c747b3e0f48 236 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 71 7.8E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS12695 95f4654ef60c31d3b754641d2ff1f247 406 Pfam PF08281 Sigma-70, region 4 101 151 2.6E-6 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS12695 95f4654ef60c31d3b754641d2ff1f247 406 SUPERFAMILY SSF88659 95 154 2.03E-9 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS12695 95f4654ef60c31d3b754641d2ff1f247 406 Gene3D G3DSA:1.10.10.10 70 155 8.3E-10 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12695 95f4654ef60c31d3b754641d2ff1f247 406 Gene3D G3DSA:1.25.40.10 178 403 1.5E-5 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS12695 95f4654ef60c31d3b754641d2ff1f247 406 SUPERFAMILY SSF88946 13 86 9.02E-9 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS12695 95f4654ef60c31d3b754641d2ff1f247 406 Pfam PF04542 Sigma-70 region 2 16 73 3.0E-5 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS12695 95f4654ef60c31d3b754641d2ff1f247 406 Gene3D G3DSA:1.10.1740.10 2 69 7.1E-9 T 28-03-2018 CNX65_RS19045 4c4bb15e72d9470d9f308b7aa891984b 122 Gene3D G3DSA:3.30.450.30 1 120 8.3E-22 T 28-03-2018 CNX65_RS09840 dd4d0814f42c69194416114c9d5dc75a 478 Gene3D G3DSA:2.115.10.20 62 334 1.2E-27 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS09840 dd4d0814f42c69194416114c9d5dc75a 478 SUPERFAMILY SSF110221 344 476 1.44E-35 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS09840 dd4d0814f42c69194416114c9d5dc75a 478 Gene3D G3DSA:2.80.10.50 335 478 1.2E-43 T 28-03-2018 CNX65_RS09840 dd4d0814f42c69194416114c9d5dc75a 478 Pfam PF05270 Alpha-L-arabinofuranosidase B (ABFB) domain 346 476 4.2E-42 T 28-03-2018 IPR007934 Alpha-L-arabinofuranosidase B, arabinose-binding domain GO:0046373|GO:0046556 CNX65_RS09840 dd4d0814f42c69194416114c9d5dc75a 478 SUPERFAMILY SSF75005 91 309 1.57E-14 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS26855 6f54f225401d51b389e33ec2d6e9decf 679 SMART SM00382 455 587 3.8E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS26855 6f54f225401d51b389e33ec2d6e9decf 679 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 460 584 3.7E-23 T 28-03-2018 IPR003959 ATPase, AAA-type, core GO:0005524 CNX65_RS26855 6f54f225401d51b389e33ec2d6e9decf 679 SUPERFAMILY SSF52540 411 638 8.78E-38 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26855 6f54f225401d51b389e33ec2d6e9decf 679 Gene3D G3DSA:3.40.50.300 403 598 2.1E-30 T 28-03-2018 CNX65_RS15940 6180ef9c55263af666184eeafd815a4f 391 Pfam PF01474 Class-II DAHP synthetase family 18 178 3.6E-44 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CNX65_RS15940 6180ef9c55263af666184eeafd815a4f 391 Pfam PF01474 Class-II DAHP synthetase family 183 387 2.7E-73 T 28-03-2018 IPR002480 DAHP synthetase, class II GO:0003849|GO:0009073 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 CNX65_RS15940 6180ef9c55263af666184eeafd815a4f 391 SUPERFAMILY SSF51569 17 389 1.46E-130 T 28-03-2018 CNX65_RS15830 85873b477cfc68f57bc88e17ebb4994b 86 Gene3D G3DSA:1.10.1200.10 4 85 3.6E-9 T 28-03-2018 CNX65_RS15830 85873b477cfc68f57bc88e17ebb4994b 86 Pfam PF00550 Phosphopantetheine attachment site 28 77 4.4E-8 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS15830 85873b477cfc68f57bc88e17ebb4994b 86 SUPERFAMILY SSF47336 30 83 5.37E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS21380 615286c15dd2faf419a44279a9c8b203 135 Gene3D G3DSA:3.30.1330.40 2 135 1.8E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS21380 615286c15dd2faf419a44279a9c8b203 135 SUPERFAMILY SSF55298 1 134 3.77E-26 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS21380 615286c15dd2faf419a44279a9c8b203 135 Pfam PF01042 Endoribonuclease L-PSP 15 133 3.3E-18 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CNX65_RS00300 23a0291cf2706118f5228fd2f4785707 791 Gene3D G3DSA:3.40.50.2000 511 727 3.3E-33 T 28-03-2018 CNX65_RS00300 23a0291cf2706118f5228fd2f4785707 791 SUPERFAMILY SSF53756 496 735 1.26E-33 T 28-03-2018 CNX65_RS00300 23a0291cf2706118f5228fd2f4785707 791 Pfam PF00534 Glycosyl transferases group 1 552 673 1.9E-15 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS13640 afd6b491079d50b7dea49a694f9f037c 80 PRINTS PR00352 3Fe-4S ferredoxin signature 53 65 9.1E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS13640 afd6b491079d50b7dea49a694f9f037c 80 PRINTS PR00352 3Fe-4S ferredoxin signature 25 35 9.1E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS13640 afd6b491079d50b7dea49a694f9f037c 80 PRINTS PR00352 3Fe-4S ferredoxin signature 14 25 9.1E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS13640 afd6b491079d50b7dea49a694f9f037c 80 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 14 67 8.0E-11 T 28-03-2018 CNX65_RS13640 afd6b491079d50b7dea49a694f9f037c 80 SUPERFAMILY SSF54862 11 69 2.72E-8 T 28-03-2018 CNX65_RS13640 afd6b491079d50b7dea49a694f9f037c 80 Gene3D G3DSA:3.30.70.20 9 70 6.0E-7 T 28-03-2018 CNX65_RS10105 30497a80fb38d828ac0dde1e0087a9d7 75 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 22 69 4.5E-10 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CNX65_RS10105 30497a80fb38d828ac0dde1e0087a9d7 75 Pfam PF12728 Helix-turn-helix domain 22 70 9.1E-8 T 28-03-2018 CNX65_RS34695 06cb12cfedcec840001217e611a62a65 143 SUPERFAMILY SSF50475 17 132 3.55E-26 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS34695 06cb12cfedcec840001217e611a62a65 143 Gene3D G3DSA:2.30.110.10 10 140 5.0E-25 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS34695 06cb12cfedcec840001217e611a62a65 143 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 11 94 2.6E-13 T 28-03-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 CNX65_RS34695 06cb12cfedcec840001217e611a62a65 143 TIGRFAM TIGR03618 Rv1155_F420: PPOX class probable F420-dependent enzyme 11 136 2.4E-35 T 28-03-2018 IPR019920 F420-binding domain, putative CNX65_RS25850 c4a4636c5aed77cee568aeee356f00d3 77 Pfam PF03840 Preprotein translocase SecG subunit 4 73 1.9E-17 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CNX65_RS25850 c4a4636c5aed77cee568aeee356f00d3 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 1.0E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CNX65_RS25850 c4a4636c5aed77cee568aeee356f00d3 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 1.0E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CNX65_RS25850 c4a4636c5aed77cee568aeee356f00d3 77 PRINTS PR01651 Protein-export SecG membrane protein signature 54 76 1.0E-6 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CNX65_RS25850 c4a4636c5aed77cee568aeee356f00d3 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 3 73 3.4E-20 T 28-03-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 CNX65_RS28600 7443096703a1cbacf3e2a2ecae5b327d 336 SUPERFAMILY SSF64182 21 322 1.44E-51 T 28-03-2018 CNX65_RS28600 7443096703a1cbacf3e2a2ecae5b327d 336 Pfam PF02272 DHHA1 domain 233 321 7.5E-12 T 28-03-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 CNX65_RS28600 7443096703a1cbacf3e2a2ecae5b327d 336 Pfam PF01368 DHH family 21 162 3.9E-11 T 28-03-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 CNX65_RS28600 7443096703a1cbacf3e2a2ecae5b327d 336 Gene3D G3DSA:3.90.1640.10 2 202 3.4E-33 T 28-03-2018 CNX65_RS19070 4f56da5ed31aecaccc0d141b2a5603b8 523 SUPERFAMILY SSF51905 434 478 4.21E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19070 4f56da5ed31aecaccc0d141b2a5603b8 523 SUPERFAMILY SSF51905 26 340 4.21E-42 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19070 4f56da5ed31aecaccc0d141b2a5603b8 523 Pfam PF01593 Flavin containing amine oxidoreductase 33 474 1.1E-28 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS19070 4f56da5ed31aecaccc0d141b2a5603b8 523 Gene3D G3DSA:3.50.50.60 22 479 3.3E-30 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS07450 509f689788f171ce52ed07fb89bd55c8 257 Pfam PF00005 ABC transporter 21 172 3.3E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS07450 509f689788f171ce52ed07fb89bd55c8 257 SUPERFAMILY SSF52540 3 232 2.02E-60 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS07450 509f689788f171ce52ed07fb89bd55c8 257 SMART SM00382 30 220 6.7E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS07450 509f689788f171ce52ed07fb89bd55c8 257 Gene3D G3DSA:3.40.50.300 2 241 3.2E-58 T 28-03-2018 CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 Gene3D G3DSA:3.40.50.720 1 305 9.6E-59 T 28-03-2018 CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 1.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 197 214 1.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 16 33 1.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 90 101 1.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 174 193 1.4E-15 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 SUPERFAMILY SSF51735 13 264 1.14E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 174 193 1.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 149 1.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 90 101 1.4E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS06630 1784ea098f33cd9dcaa52215f721ecc7 307 Pfam PF00106 short chain dehydrogenase 16 217 1.8E-27 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS30125 555cd2382205794942fde6ff6653691d 135 Gene3D G3DSA:2.60.40.10 30 132 6.8E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS00610 fc93f3e8047a4fe3a7e257614ac7d01b 310 SUPERFAMILY SSF51679 31 307 1.44E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS00610 fc93f3e8047a4fe3a7e257614ac7d01b 310 Gene3D G3DSA:3.20.20.30 12 254 6.6E-54 T 28-03-2018 CNX65_RS00610 fc93f3e8047a4fe3a7e257614ac7d01b 310 Pfam PF00296 Luciferase-like monooxygenase 35 236 9.1E-43 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS13625 f5d7ee7419a528c3a4784d1251e366c8 419 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 226 239 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CNX65_RS13625 f5d7ee7419a528c3a4784d1251e366c8 419 Pfam PF00155 Aminotransferase class I and II 38 374 5.9E-35 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS13625 f5d7ee7419a528c3a4784d1251e366c8 419 SUPERFAMILY SSF53383 6 373 1.63E-61 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS13625 f5d7ee7419a528c3a4784d1251e366c8 419 Gene3D G3DSA:3.90.1150.10 277 396 7.4E-9 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS13625 f5d7ee7419a528c3a4784d1251e366c8 419 Gene3D G3DSA:3.40.640.10 39 276 6.9E-39 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS09955 d5f75a14977d5f35dcb96bf55615f80b 306 Pfam PF03631 Virulence factor BrkB 29 282 1.6E-62 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS09955 d5f75a14977d5f35dcb96bf55615f80b 306 PIRSF PIRSF035875 2 304 8.6E-80 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS09955 d5f75a14977d5f35dcb96bf55615f80b 306 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 21 280 7.8E-28 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS05915 45e2dce5174ffd79f58c33fa2562dac9 103 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 7.0E-35 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05915 45e2dce5174ffd79f58c33fa2562dac9 103 SUPERFAMILY SSF141091 1 100 1.96E-32 T 28-03-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05915 45e2dce5174ffd79f58c33fa2562dac9 103 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 23.115 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05915 45e2dce5174ffd79f58c33fa2562dac9 103 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 100 2.0E-26 T 28-03-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS05915 45e2dce5174ffd79f58c33fa2562dac9 103 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 28-03-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS02845 1d6d5d0939840e015f852c1cf7d61b5e 285 Gene3D G3DSA:1.20.5.1230 74 278 5.1E-5 T 28-03-2018 CNX65_RS06540 231391deab2e63085aace606a4742037 411 SUPERFAMILY SSF53901 6 254 2.04E-63 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS06540 231391deab2e63085aace606a4742037 411 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 6 247 4.9E-55 T 28-03-2018 IPR014030 Beta-ketoacyl synthase, N-terminal CNX65_RS06540 231391deab2e63085aace606a4742037 411 SUPERFAMILY SSF53901 216 409 2.56E-64 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS06540 231391deab2e63085aace606a4742037 411 PIRSF PIRSF000447 4 411 1.1E-138 T 28-03-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 CNX65_RS06540 231391deab2e63085aace606a4742037 411 SMART SM00825 Beta-ketoacyl synthase 7 408 4.2E-15 T 28-03-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain CNX65_RS06540 231391deab2e63085aace606a4742037 411 Gene3D G3DSA:3.40.47.10 265 411 2.5E-44 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS06540 231391deab2e63085aace606a4742037 411 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 257 368 5.5E-31 T 28-03-2018 IPR014031 Beta-ketoacyl synthase, C-terminal CNX65_RS06540 231391deab2e63085aace606a4742037 411 Gene3D G3DSA:3.40.47.10 1 261 1.0E-65 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS26195 3729019a22b575b3f3f5ca7a974e64ce 409 Gene3D G3DSA:3.30.160.60 372 403 4.6E-7 T 28-03-2018 CNX65_RS26195 3729019a22b575b3f3f5ca7a974e64ce 409 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 40 409 26.62 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CNX65_RS26195 3729019a22b575b3f3f5ca7a974e64ce 409 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 44 401 8.8E-39 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CNX65_RS26195 3729019a22b575b3f3f5ca7a974e64ce 409 Pfam PF02618 YceG-like family 81 398 1.9E-59 T 28-03-2018 IPR003770 Endolytic murein transglycosylase CNX65_RS10690 a5b3852c1e2424540af021e8353b24e6 330 SUPERFAMILY SSF51679 2 328 8.9E-53 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS10690 a5b3852c1e2424540af021e8353b24e6 330 Gene3D G3DSA:3.20.20.30 1 330 2.9E-56 T 28-03-2018 CNX65_RS10690 a5b3852c1e2424540af021e8353b24e6 330 Pfam PF00296 Luciferase-like monooxygenase 8 305 3.4E-47 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS10690 a5b3852c1e2424540af021e8353b24e6 330 TIGRFAM TIGR03842 F420_CPS_4043: F420-dependent oxidoreductase, CPS_4043 family 2 330 9.1E-178 T 28-03-2018 IPR022315 F420-dependent oxidoreductase-predicted, CPS4043 CNX65_RS19660 be8883c99c0dd479f7d5f3f5c4da20a0 360 SUPERFAMILY SSF81345 16 350 4.32E-83 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS19660 be8883c99c0dd479f7d5f3f5c4da20a0 360 Pfam PF01032 FecCD transport family 32 349 5.6E-92 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS19660 be8883c99c0dd479f7d5f3f5c4da20a0 360 Gene3D G3DSA:1.10.3470.10 16 358 1.7E-73 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS15410 a0c67a604292392ebc24170ac94c4cfa 189 SUPERFAMILY SSF100950 33 189 3.64E-30 T 28-03-2018 CNX65_RS15410 a0c67a604292392ebc24170ac94c4cfa 189 Gene3D G3DSA:3.40.50.10420 32 189 2.5E-37 T 28-03-2018 CNX65_RS15410 a0c67a604292392ebc24170ac94c4cfa 189 Pfam PF02589 LUD domain 92 189 1.6E-18 T 28-03-2018 IPR003741 LUD domain CNX65_RS24580 6bc5ae5322af617b268b7e3379e69d5f 200 Pfam PF09335 SNARE associated Golgi protein 34 159 3.7E-23 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS04730 45c520593cc9ff3cf72a56dbeed122c7 490 Pfam PF14362 Domain of unknown function (DUF4407) 16 351 1.9E-79 T 28-03-2018 IPR025519 Protein of unknown function DUF4407 CNX65_RS10335 cc997369b9f4c0ab4891514b60980eaa 487 Pfam PF13560 Helix-turn-helix domain 26 83 2.9E-8 T 28-03-2018 CNX65_RS10335 cc997369b9f4c0ab4891514b60980eaa 487 Gene3D G3DSA:1.10.260.40 17 85 2.1E-13 T 28-03-2018 CNX65_RS10335 cc997369b9f4c0ab4891514b60980eaa 487 SMART SM00530 29 84 1.3E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS10335 cc997369b9f4c0ab4891514b60980eaa 487 SUPERFAMILY SSF47413 26 84 4.02E-11 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS17475 06f0348d1382a610a3f651ddc817e927 262 SUPERFAMILY SSF53098 10 207 4.83E-42 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS17475 06f0348d1382a610a3f651ddc817e927 262 Pfam PF00929 Exonuclease 17 184 2.1E-10 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS17475 06f0348d1382a610a3f651ddc817e927 262 SMART SM00479 14 194 3.6E-13 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS17475 06f0348d1382a610a3f651ddc817e927 262 Gene3D G3DSA:3.30.420.10 14 196 2.3E-28 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS25010 b6525aa5ad84b7946bc1bf41f5551a46 77 Gene3D G3DSA:3.90.20.10 5 63 8.0E-4 T 28-03-2018 CNX65_RS10985 e77791ed46278765fa67f47c366eadb7 149 Gene3D G3DSA:3.30.1310.10 10 107 2.1E-17 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS10985 e77791ed46278765fa67f47c366eadb7 149 Pfam PF02575 YbaB/EbfC DNA-binding family 19 96 3.2E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS10985 e77791ed46278765fa67f47c366eadb7 149 SUPERFAMILY SSF82607 19 94 3.66E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS34825 8235a31391a29e303e00033b99884d3a 391 SUPERFAMILY SSF53098 3 153 6.51E-35 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS34825 8235a31391a29e303e00033b99884d3a 391 Gene3D G3DSA:3.40.50.10190 306 378 2.4E-6 T 28-03-2018 IPR001357 BRCT domain CNX65_RS34825 8235a31391a29e303e00033b99884d3a 391 Pfam PF00929 Exonuclease 5 150 1.1E-15 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS34825 8235a31391a29e303e00033b99884d3a 391 SMART SM00479 2 159 1.6E-22 T 28-03-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III CNX65_RS34825 8235a31391a29e303e00033b99884d3a 391 Gene3D G3DSA:3.30.420.10 2 155 1.2E-25 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS34825 8235a31391a29e303e00033b99884d3a 391 SUPERFAMILY SSF52113 304 376 9.16E-5 T 28-03-2018 IPR001357 BRCT domain CNX65_RS32970 5afe00554b595b6f59c0063d04223273 96 Pfam PF06243 Phenylacetic acid degradation B 7 92 4.7E-39 T 28-03-2018 IPR009359 Phenylacetic acid degradation B CNX65_RS32970 5afe00554b595b6f59c0063d04223273 96 PIRSF PIRSF030200 1 96 5.8E-44 T 28-03-2018 IPR009359 Phenylacetic acid degradation B CNX65_RS32970 5afe00554b595b6f59c0063d04223273 96 TIGRFAM TIGR02157 PA_CoA_Oxy2: phenylacetate-CoA oxygenase, PaaH subunit 7 95 9.7E-45 T 28-03-2018 IPR009359 Phenylacetic acid degradation B CNX65_RS07630 f342d90d0a39418c81a3e82e952cd2f7 254 Gene3D G3DSA:3.20.20.410 2 252 2.3E-81 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CNX65_RS07630 f342d90d0a39418c81a3e82e952cd2f7 254 Pfam PF01904 Protein of unknown function DUF72 23 236 3.8E-62 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CNX65_RS07630 f342d90d0a39418c81a3e82e952cd2f7 254 SUPERFAMILY SSF117396 5 239 3.66E-73 T 28-03-2018 IPR002763 Protein of unknown function DUF72 CNX65_RS33675 de33f033d4a1a9b242808907ac3efeae 375 Gene3D G3DSA:3.30.70.1230 4 214 2.4E-19 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS33675 de33f033d4a1a9b242808907ac3efeae 375 SUPERFAMILY SSF55073 13 156 9.26E-19 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS33675 de33f033d4a1a9b242808907ac3efeae 375 SUPERFAMILY SSF50249 233 300 2.69E-6 T 28-03-2018 IPR012340 Nucleic acid-binding, OB-fold CNX65_RS33675 de33f033d4a1a9b242808907ac3efeae 375 Gene3D G3DSA:2.40.50.140 225 305 1.3E-6 T 28-03-2018 CNX65_RS08815 f7da573284d3bd6f000d933b5b2f7660 318 PIRSF PIRSF035875 12 311 9.5E-48 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS08815 f7da573284d3bd6f000d933b5b2f7660 318 Pfam PF03631 Virulence factor BrkB 40 293 9.2E-39 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS33080 896fc106d293cb81f01537bf4ca7797f 539 Pfam PF05140 ResB-like family 39 521 7.1E-133 T 28-03-2018 IPR007816 ResB-like domain CNX65_RS02790 512a9570ec48fc4d13c14844874b6d09 263 Gene3D G3DSA:3.40.50.1820 5 263 1.4E-40 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02790 512a9570ec48fc4d13c14844874b6d09 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 97 110 1.7E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS02790 512a9570ec48fc4d13c14844874b6d09 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 111 124 1.7E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS02790 512a9570ec48fc4d13c14844874b6d09 263 PRINTS PR00111 Alpha/beta hydrolase fold signature 51 66 1.7E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS02790 512a9570ec48fc4d13c14844874b6d09 263 Pfam PF12146 Serine aminopeptidase, S33 28 244 6.7E-48 T 28-03-2018 IPR022742 Serine aminopeptidase, S33 CNX65_RS02790 512a9570ec48fc4d13c14844874b6d09 263 SUPERFAMILY SSF53474 10 129 1.01E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02790 512a9570ec48fc4d13c14844874b6d09 263 SUPERFAMILY SSF53474 186 258 1.01E-37 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16975 39d672c7032a8292e9b4be5a66d45126 207 Gene3D G3DSA:3.90.79.10 22 194 3.1E-17 T 28-03-2018 CNX65_RS16975 39d672c7032a8292e9b4be5a66d45126 207 SUPERFAMILY SSF55811 66 172 1.49E-17 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS16975 39d672c7032a8292e9b4be5a66d45126 207 Pfam PF00293 NUDIX domain 74 195 1.8E-13 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS16975 39d672c7032a8292e9b4be5a66d45126 207 ProSitePatterns PS00893 Nudix box signature. 102 123 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS32440 8a12a1afdc95f2c99a5cb7e62fa91d46 99 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 6 96 21.256 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32440 8a12a1afdc95f2c99a5cb7e62fa91d46 99 ProSitePatterns PS00050 Ribosomal protein L23 signature. 78 93 - T 28-03-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32440 8a12a1afdc95f2c99a5cb7e62fa91d46 99 SUPERFAMILY SSF54189 4 92 9.71E-32 T 28-03-2018 IPR012678 Ribosomal protein L23/L15e core domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32440 8a12a1afdc95f2c99a5cb7e62fa91d46 99 Pfam PF00276 Ribosomal protein L23 7 89 2.4E-31 T 28-03-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 CNX65_RS32440 8a12a1afdc95f2c99a5cb7e62fa91d46 99 Gene3D G3DSA:3.30.70.330 3 98 6.1E-31 T 28-03-2018 CNX65_RS32090 8e9a7c739d13b0056e71eb669392c7dd 450 Gene3D G3DSA:1.25.40.10 4 423 7.0E-10 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS08920 b6b2ce4f4cd7a10ed0b642e88333103c 86 SUPERFAMILY SSF143011 2 83 1.57E-25 T 28-03-2018 IPR035095 Toxin RelE-like domain CNX65_RS08920 b6b2ce4f4cd7a10ed0b642e88333103c 86 Pfam PF06769 YoeB-like toxin of bacterial type II toxin-antitoxin system 5 84 6.5E-37 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CNX65_RS08920 b6b2ce4f4cd7a10ed0b642e88333103c 86 Gene3D G3DSA:3.30.2310.20 1 84 1.8E-23 T 28-03-2018 CNX65_RS08920 b6b2ce4f4cd7a10ed0b642e88333103c 86 TIGRFAM TIGR02116 toxin_Txe_YoeB: addiction module toxin, Txe/YoeB family 5 84 5.0E-33 T 28-03-2018 IPR009614 Toxin YoeB GO:0004519|GO:0006401 CNX65_RS02925 f8fc01a75ce98aed0f0b467774b8223f 156 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS02925 f8fc01a75ce98aed0f0b467774b8223f 156 Pfam PF00293 NUDIX domain 18 130 1.6E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS02925 f8fc01a75ce98aed0f0b467774b8223f 156 Gene3D G3DSA:3.90.79.10 9 151 1.5E-26 T 28-03-2018 CNX65_RS02925 f8fc01a75ce98aed0f0b467774b8223f 156 PRINTS PR00502 NUDIX hydrolase family signature 44 58 1.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS02925 f8fc01a75ce98aed0f0b467774b8223f 156 PRINTS PR00502 NUDIX hydrolase family signature 58 73 1.0E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS02925 f8fc01a75ce98aed0f0b467774b8223f 156 SUPERFAMILY SSF55811 6 149 1.9E-32 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS02925 f8fc01a75ce98aed0f0b467774b8223f 156 ProDom PD037294 PEPTIDE ACMNPV ORF38 ORF ORF_59 ORF61 ORF7 PXORF52 ORF-30 ORF79 42 115 2.0E-4 T 28-03-2018 CNX65_RS11525 f619415df69931c231dc64232bafbd36 315 Gene3D G3DSA:3.60.70.12 1 304 8.5E-70 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS11525 f619415df69931c231dc64232bafbd36 315 Pfam PF03576 Peptidase family S58 3 293 1.4E-42 T 28-03-2018 IPR005321 Peptidase S58, DmpA CNX65_RS11525 f619415df69931c231dc64232bafbd36 315 SUPERFAMILY SSF56266 2 290 1.88E-41 T 28-03-2018 IPR016117 ArgJ-like domain KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 CNX65_RS00055 4780b924eff7330e3a95e76d4b36c9de 143 Pfam PF07681 DoxX 12 87 1.1E-11 T 28-03-2018 IPR032808 DoxX family CNX65_RS34770 17318bc9b2daebbe1c83acf6cc4e9f88 256 SUPERFAMILY SSF51658 1 252 1.1E-57 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS34770 17318bc9b2daebbe1c83acf6cc4e9f88 256 SMART SM00518 2 254 1.4E-52 T 28-03-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 CNX65_RS34770 17318bc9b2daebbe1c83acf6cc4e9f88 256 Pfam PF01261 Xylose isomerase-like TIM barrel 13 218 6.7E-28 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS34770 17318bc9b2daebbe1c83acf6cc4e9f88 256 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 162 169 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CNX65_RS34770 17318bc9b2daebbe1c83acf6cc4e9f88 256 Gene3D G3DSA:3.20.20.150 1 256 6.1E-42 T 28-03-2018 CNX65_RS34770 17318bc9b2daebbe1c83acf6cc4e9f88 256 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 56 64 - T 28-03-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 CNX65_RS02110 68eb172e511d613fa0c5d552ea372909 139 SMART SM00347 23 123 8.2E-21 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS02110 68eb172e511d613fa0c5d552ea372909 139 Gene3D G3DSA:1.10.287.100 106 138 5.3E-8 T 28-03-2018 CNX65_RS02110 68eb172e511d613fa0c5d552ea372909 139 ProSitePatterns PS01117 MarR-type HTH domain signature. 62 96 - T 28-03-2018 IPR023187 Transcriptional regulator MarR-type, conserved site CNX65_RS02110 68eb172e511d613fa0c5d552ea372909 139 Pfam PF01047 MarR family 35 87 3.8E-14 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS02110 68eb172e511d613fa0c5d552ea372909 139 Gene3D G3DSA:1.10.10.10 2 105 3.1E-17 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02110 68eb172e511d613fa0c5d552ea372909 139 SUPERFAMILY SSF46785 10 138 3.25E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS13110 36f956e96ba90c1cde6a46b5c57b2b71 286 SUPERFAMILY SSF160424 154 283 1.96E-11 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS13110 36f956e96ba90c1cde6a46b5c57b2b71 286 SUPERFAMILY SSF160424 17 138 8.89E-15 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS15220 a88a016a3e7ac7f680c34955fdca769c 185 SUPERFAMILY SSF52218 4 177 9.66E-39 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS15220 a88a016a3e7ac7f680c34955fdca769c 185 Gene3D G3DSA:3.40.50.360 1 184 1.3E-31 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS15220 a88a016a3e7ac7f680c34955fdca769c 185 Pfam PF03358 NADPH-dependent FMN reductase 4 149 1.3E-32 T 28-03-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 CNX65_RS24415 b34cdf7d98e7c301561539d0c3bc5925 281 Pfam PF03631 Virulence factor BrkB 28 268 3.2E-13 T 28-03-2018 IPR017039 Virulence factor BrkB CNX65_RS10390 bd41032006426a590424b9cb224e763e 64 Gene3D G3DSA:2.10.109.10 4 57 1.3E-4 T 28-03-2018 CNX65_RS10390 bd41032006426a590424b9cb224e763e 64 ProSitePatterns PS00501 Signal peptidases I serine active site. 11 18 - T 28-03-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 CNX65_RS02415 6948a4e28c7e60bcac322de940a2e4d9 274 Pfam PF00149 Calcineurin-like phosphoesterase 18 195 4.8E-8 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS02415 6948a4e28c7e60bcac322de940a2e4d9 274 SUPERFAMILY SSF56300 16 263 1.3E-31 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS02415 6948a4e28c7e60bcac322de940a2e4d9 274 PRINTS PR00114 Serine/threonine phosphatase family signature 54 81 3.4E-7 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS02415 6948a4e28c7e60bcac322de940a2e4d9 274 PRINTS PR00114 Serine/threonine phosphatase family signature 17 44 3.4E-7 T 28-03-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS02415 6948a4e28c7e60bcac322de940a2e4d9 274 Gene3D G3DSA:3.60.21.10 6 273 2.2E-34 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS16030 a3057dfcad4c3dbf8cbf5fee27a16ec4 391 Pfam PF00149 Calcineurin-like phosphoesterase 165 332 6.6E-11 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS16030 a3057dfcad4c3dbf8cbf5fee27a16ec4 391 Gene3D G3DSA:3.60.21.10 164 378 1.4E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS16030 a3057dfcad4c3dbf8cbf5fee27a16ec4 391 SUPERFAMILY SSF56300 165 390 5.83E-37 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS33385 1d601009ce70b886823e992953a695e2 194 Gene3D G3DSA:1.20.120.20 6 184 3.3E-6 T 28-03-2018 CNX65_RS33385 1d601009ce70b886823e992953a695e2 194 ProDom PD082580 HEPARIN-BINDING HEMAGGLUTININ ADHESIN GLYCOPROTEIN DIRECT VIRULENCE SEQUENCING CELL ADHESION HOMOLOG 41 143 1.0E-9 T 28-03-2018 IPR020340 Heparin-binding haemagglutinin, bacteria GO:0007155|GO:0008201|GO:0009405|GO:0009986 CNX65_RS31360 e8781a72f5e43834e92dcf8938c2a4b4 163 Gene3D G3DSA:3.30.1310.10 1 108 8.9E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS31360 e8781a72f5e43834e92dcf8938c2a4b4 163 Pfam PF02575 YbaB/EbfC DNA-binding family 19 96 5.5E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS31360 e8781a72f5e43834e92dcf8938c2a4b4 163 SUPERFAMILY SSF82607 21 94 3.79E-5 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS23770 47b5cc9fc62275eaefdde9f39e1888a6 107 Gene3D G3DSA:1.10.10.60 29 66 7.5E-18 T 28-03-2018 CNX65_RS23770 47b5cc9fc62275eaefdde9f39e1888a6 107 Gene3D G3DSA:1.10.10.60 67 96 2.4E-11 T 28-03-2018 CNX65_RS23770 47b5cc9fc62275eaefdde9f39e1888a6 107 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 35 48 3.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23770 47b5cc9fc62275eaefdde9f39e1888a6 107 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 56 79 3.7E-6 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS23770 47b5cc9fc62275eaefdde9f39e1888a6 107 SUPERFAMILY SSF46689 31 95 2.74E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS23770 47b5cc9fc62275eaefdde9f39e1888a6 107 Pfam PF00440 Bacterial regulatory proteins, tetR family 35 81 1.1E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS01230 cbac40b989f7ee1722413e7f49005771 155 Pfam PF07332 Putative Actinobacterial Holin-X, holin superfamily III 32 146 4.8E-32 T 28-03-2018 IPR009937 Putative Actinobacterial Holin-X, holin superfamily III CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 Gene3D G3DSA:3.40.640.10 123 393 1.7E-52 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 379 394 2.8E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 154 173 2.8E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 114 133 2.8E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 PRINTS PR00800 Aromatic-L-amino-acid decarboxylase signature 422 441 2.8E-8 T 28-03-2018 IPR010977 Aromatic-L-amino-acid decarboxylase GO:0006520|GO:0016831 CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 SUPERFAMILY SSF53383 47 508 1.14E-107 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 113 441 3.9E-45 T 28-03-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 CNX65_RS11530 6ce1de62d1d1ab7f14ffbd2368870c5a 512 Gene3D G3DSA:3.90.1150.10 394 510 7.5E-31 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS00735 1c9c285e7cd1ff7e8f878e419fd3dce5 249 Pfam PF01925 Sulfite exporter TauE/SafE 10 245 2.5E-40 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CNX65_RS18885 9b2cfe4e0f716f030aa85ca5300794e4 397 Gene3D G3DSA:1.20.1250.20 189 394 1.9E-15 T 28-03-2018 CNX65_RS18885 9b2cfe4e0f716f030aa85ca5300794e4 397 Pfam PF05977 Transmembrane secretion effector 9 392 9.3E-28 T 28-03-2018 IPR010290 Transmembrane secretion effector CNX65_RS18885 9b2cfe4e0f716f030aa85ca5300794e4 397 SUPERFAMILY SSF103473 2 389 1.44E-32 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS18885 9b2cfe4e0f716f030aa85ca5300794e4 397 Gene3D G3DSA:1.20.1250.20 1 180 7.2E-12 T 28-03-2018 CNX65_RS17445 cb4c6c3722d29c7c1afe6a9bf0c86e71 86 Pfam PF13560 Helix-turn-helix domain 16 76 1.2E-12 T 28-03-2018 CNX65_RS17445 cb4c6c3722d29c7c1afe6a9bf0c86e71 86 SMART SM00530 20 74 1.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS17445 cb4c6c3722d29c7c1afe6a9bf0c86e71 86 Gene3D G3DSA:1.10.260.40 7 62 1.7E-15 T 28-03-2018 CNX65_RS17445 cb4c6c3722d29c7c1afe6a9bf0c86e71 86 SUPERFAMILY SSF47413 11 76 1.3E-17 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS17445 cb4c6c3722d29c7c1afe6a9bf0c86e71 86 Gene3D G3DSA:1.10.10.60 63 85 0.15 T 28-03-2018 CNX65_RS20985 67cf43149a1195aee66558630846b356 1250 Gene3D G3DSA:3.40.50.300 4 131 0.0011 T 28-03-2018 CNX65_RS20985 67cf43149a1195aee66558630846b356 1250 SUPERFAMILY SSF52540 7 110 7.3E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26620 6324747633aa6ddcac4eb08aa09a8d31 596 SUPERFAMILY SSF53850 59 360 5.67E-8 T 28-03-2018 CNX65_RS26620 6324747633aa6ddcac4eb08aa09a8d31 596 Gene3D G3DSA:3.40.50.410 420 593 1.0E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS26620 6324747633aa6ddcac4eb08aa09a8d31 596 SMART SM00327 404 593 1.3E-7 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS26620 6324747633aa6ddcac4eb08aa09a8d31 596 Gene3D G3DSA:3.40.190.10 155 419 9.4E-7 T 28-03-2018 CNX65_RS26620 6324747633aa6ddcac4eb08aa09a8d31 596 Pfam PF13519 von Willebrand factor type A domain 408 522 3.5E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS26620 6324747633aa6ddcac4eb08aa09a8d31 596 SUPERFAMILY SSF53300 407 592 1.34E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS26620 6324747633aa6ddcac4eb08aa09a8d31 596 Pfam PF13531 Bacterial extracellular solute-binding protein 61 360 1.1E-22 T 28-03-2018 CNX65_RS28920 dc35c5429fac1a4efc480cc475a00804 555 SUPERFAMILY SSF55874 287 405 2.51E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS28920 dc35c5429fac1a4efc480cc475a00804 555 Gene3D G3DSA:3.30.565.10 284 408 4.2E-17 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS28920 dc35c5429fac1a4efc480cc475a00804 555 Pfam PF07730 Histidine kinase 209 273 9.4E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS00365 07b7d0339534ad7ed40388d85c333a42 118 Pfam PF04341 Protein of unknown function, DUF485 24 110 3.6E-34 T 28-03-2018 IPR007436 Protein of unknown function DUF485 CNX65_RS09060 d17d1dd23b26047ab9fbf28b69982a63 167 Gene3D G3DSA:3.40.10.10 55 156 6.1E-8 T 28-03-2018 IPR035451 Ada-like domain CNX65_RS03500 9a7f2ad2e71fafaac5b657c65397600b 90 Pfam PF10041 Uncharacterized conserved protein (DUF2277) 2 78 2.1E-35 T 28-03-2018 IPR018735 Protein of unknown function DUF2277 CNX65_RS09405 551080f0aa0a15d09b7c46506528a172 638 Pfam PF04434 SWIM zinc finger 60 87 4.1E-5 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CNX65_RS13680 93595505ec8b555612283f18e5963c39 361 SUPERFAMILY SSF75005 90 347 4.43E-23 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS13680 93595505ec8b555612283f18e5963c39 361 Gene3D G3DSA:2.115.10.20 24 116 1.4E-5 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS13680 93595505ec8b555612283f18e5963c39 361 Gene3D G3DSA:2.115.10.20 117 350 1.1E-23 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS13055 b1422ffc14b8b35f97c4959b05dc708d 269 Gene3D G3DSA:1.10.3720.10 1 256 3.0E-39 T 28-03-2018 CNX65_RS13055 b1422ffc14b8b35f97c4959b05dc708d 269 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 80 255 1.1E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS13055 b1422ffc14b8b35f97c4959b05dc708d 269 SUPERFAMILY SSF161098 2 268 8.76E-55 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14960 a43d895f0d4639b1b70197a7804d68dd 285 Gene3D G3DSA:1.10.10.10 241 285 1.6E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08620 9e1a0ad3f8f644888f358de52ee93b33 180 Pfam PF03167 Uracil DNA glycosylase superfamily 4 159 9.6E-20 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS08620 9e1a0ad3f8f644888f358de52ee93b33 180 Gene3D G3DSA:3.40.470.10 3 175 8.6E-47 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS08620 9e1a0ad3f8f644888f358de52ee93b33 180 SUPERFAMILY SSF52141 1 160 1.87E-39 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS20115 cc3c1d0255631ac0715b76e26a235f08 213 Gene3D G3DSA:3.40.50.720 1 211 3.8E-11 T 28-03-2018 CNX65_RS20115 cc3c1d0255631ac0715b76e26a235f08 213 SUPERFAMILY SSF51735 2 210 5.28E-24 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS20115 cc3c1d0255631ac0715b76e26a235f08 213 Pfam PF13460 NAD(P)H-binding 7 198 1.8E-30 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 SUPERFAMILY SSF51735 11 254 1.19E-57 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 20 253 7.7E-38 T 28-03-2018 CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 74 85 1.8E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 1.8E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 129 137 1.8E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 218 238 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 13 30 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 74 85 1.5E-35 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 137 165 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 Gene3D G3DSA:3.40.50.720 4 47 1.8E-7 T 28-03-2018 CNX65_RS23060 b690744334ff89c26388a3ed71bfcb65 258 Gene3D G3DSA:3.40.50.720 48 256 4.8E-44 T 28-03-2018 CNX65_RS18265 cd9c010038988ec80885efabb04f954f 228 Gene3D G3DSA:1.10.357.10 58 224 2.1E-29 T 28-03-2018 CNX65_RS18265 cd9c010038988ec80885efabb04f954f 228 SUPERFAMILY SSF46689 4 78 5.49E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS18265 cd9c010038988ec80885efabb04f954f 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18265 cd9c010038988ec80885efabb04f954f 228 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 3.6E-5 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18265 cd9c010038988ec80885efabb04f954f 228 Gene3D G3DSA:1.10.10.60 3 57 3.0E-16 T 28-03-2018 CNX65_RS18265 cd9c010038988ec80885efabb04f954f 228 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 8.1E-12 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18265 cd9c010038988ec80885efabb04f954f 228 SUPERFAMILY SSF48498 84 219 3.56E-24 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS19675 f6dcdbedc566383fb29007843cd95edf 432 Pfam PF10100 Staphylopine dehydrogenase 5 428 1.2E-192 T 28-03-2018 IPR016935 Staphylopine dehydrogenase CNX65_RS19675 f6dcdbedc566383fb29007843cd95edf 432 Gene3D G3DSA:3.40.50.720 4 198 1.5E-6 T 28-03-2018 CNX65_RS21600 62eab40c34c9c390a4b7e6ab8095a89f 377 Gene3D G3DSA:1.25.40.70 126 189 0.14 T 28-03-2018 CNX65_RS21600 62eab40c34c9c390a4b7e6ab8095a89f 377 Pfam PF03130 PBS lyase HEAT-like repeat 164 184 0.0025 T 28-03-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 CNX65_RS21600 62eab40c34c9c390a4b7e6ab8095a89f 377 Gene3D G3DSA:1.25.10.10 190 351 6.4E-10 T 28-03-2018 IPR011989 Armadillo-like helical CNX65_RS21600 62eab40c34c9c390a4b7e6ab8095a89f 377 SUPERFAMILY SSF48371 164 311 3.09E-12 T 28-03-2018 IPR016024 Armadillo-type fold GO:0005488 CNX65_RS04000 f1dc1a432fe9a3a55efd37d7bba2c2d3 281 SUPERFAMILY SSF161098 15 281 1.78E-73 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS04000 f1dc1a432fe9a3a55efd37d7bba2c2d3 281 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 274 5.5E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS04000 f1dc1a432fe9a3a55efd37d7bba2c2d3 281 Gene3D G3DSA:1.10.3720.10 16 272 8.0E-45 T 28-03-2018 CNX65_RS33230 34c41f26d06b34fbccb367108ce782c9 70 Gene3D G3DSA:1.10.1660.20 15 59 2.1E-10 T 28-03-2018 CNX65_RS33230 34c41f26d06b34fbccb367108ce782c9 70 TIGRFAM TIGR01764 excise: DNA binding domain, excisionase family 16 63 3.0E-19 T 28-03-2018 IPR010093 SinI-like, DNA-binding domain GO:0003677 CNX65_RS33230 34c41f26d06b34fbccb367108ce782c9 70 Pfam PF12728 Helix-turn-helix domain 16 64 1.3E-14 T 28-03-2018 CNX65_RS25605 f9f3b8a5a1b80f185cabedd4fb4e18c4 117 Pfam PF01883 Iron-sulfur cluster assembly protein 15 79 1.8E-19 T 28-03-2018 IPR002744 MIP18 family-like CNX65_RS25605 f9f3b8a5a1b80f185cabedd4fb4e18c4 117 Gene3D G3DSA:3.30.300.130 12 112 7.7E-25 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CNX65_RS25605 f9f3b8a5a1b80f185cabedd4fb4e18c4 117 SUPERFAMILY SSF117916 15 111 8.83E-27 T 28-03-2018 IPR034904 Fe-S cluster assembly domain CNX65_RS15405 33c9c3e9b1a0e23dae535acf9a12e82d 189 Pfam PF12867 DinB superfamily 14 174 2.4E-13 T 28-03-2018 IPR024775 DinB-like domain CNX65_RS15405 33c9c3e9b1a0e23dae535acf9a12e82d 189 Gene3D G3DSA:1.20.120.450 65 188 8.9E-19 T 28-03-2018 CNX65_RS15405 33c9c3e9b1a0e23dae535acf9a12e82d 189 Gene3D G3DSA:1.20.120.450 3 48 4.1E-6 T 28-03-2018 CNX65_RS15405 33c9c3e9b1a0e23dae535acf9a12e82d 189 SUPERFAMILY SSF109854 70 181 2.9E-12 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS32865 83ff87c5dd2e3bcfea349e4155dd43c4 530 Pfam PF00361 Proton-conducting membrane transporter 172 466 1.1E-77 T 28-03-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32865 83ff87c5dd2e3bcfea349e4155dd43c4 530 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 16 520 17.73 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CNX65_RS32865 83ff87c5dd2e3bcfea349e4155dd43c4 530 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 144 519 3.1E-115 T 28-03-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 CNX65_RS23210 53a7efd2d5f9e07e8a70089f93fb7bff 306 Pfam PF07859 alpha/beta hydrolase fold 74 279 6.0E-58 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CNX65_RS23210 53a7efd2d5f9e07e8a70089f93fb7bff 306 SUPERFAMILY SSF53474 36 303 2.77E-60 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS23210 53a7efd2d5f9e07e8a70089f93fb7bff 306 Gene3D G3DSA:3.40.50.1820 5 306 3.7E-49 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS19275 32d3f4e5faf9443feb646032d7cb6a70 405 Pfam PF14028 Lantibiotic biosynthesis dehydratase C-term 51 297 4.8E-16 T 28-03-2018 IPR023809 Thiopeptide-type bacteriocin biosynthesis domain CNX65_RS27020 10d0dcbed37cb7eae946026febc67f2a 312 Gene3D G3DSA:1.10.10.580 223 291 2.5E-11 T 28-03-2018 CNX65_RS27020 10d0dcbed37cb7eae946026febc67f2a 312 Pfam PF02616 Segregation and condensation protein ScpA 70 290 1.4E-59 T 28-03-2018 IPR003768 Segregation and condensation protein A CNX65_RS09980 291fcd75470ffed06396496197d52045 380 Pfam PF07690 Major Facilitator Superfamily 207 360 3.9E-10 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS09980 291fcd75470ffed06396496197d52045 380 SUPERFAMILY SSF103473 2 355 1.57E-21 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS09980 291fcd75470ffed06396496197d52045 380 Gene3D G3DSA:1.20.1250.20 1 150 0.0045 T 28-03-2018 CNX65_RS09980 291fcd75470ffed06396496197d52045 380 Gene3D G3DSA:1.20.1250.20 170 364 5.5E-17 T 28-03-2018 CNX65_RS17495 76fb5c85e5b4951c7810ba0cf83cb9d7 273 SUPERFAMILY SSF46689 213 250 5.82E-5 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS17495 76fb5c85e5b4951c7810ba0cf83cb9d7 273 Gene3D G3DSA:1.10.10.60 213 259 2.2E-8 T 28-03-2018 CNX65_RS17495 76fb5c85e5b4951c7810ba0cf83cb9d7 273 Pfam PF12833 Helix-turn-helix domain 172 250 2.4E-14 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS17495 76fb5c85e5b4951c7810ba0cf83cb9d7 273 SMART SM00342 166 250 1.9E-6 T 28-03-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 CNX65_RS17495 76fb5c85e5b4951c7810ba0cf83cb9d7 273 Gene3D G3DSA:1.10.10.60 112 205 1.3E-5 T 28-03-2018 CNX65_RS17195 9ed2f3ec3dc4e998b57fa686c9663d55 434 Pfam PF00756 Putative esterase 193 425 1.2E-10 T 28-03-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 CNX65_RS17195 9ed2f3ec3dc4e998b57fa686c9663d55 434 SUPERFAMILY SSF53474 173 428 1.04E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17195 9ed2f3ec3dc4e998b57fa686c9663d55 434 Gene3D G3DSA:3.40.50.1820 170 431 7.8E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS00375 2bc4e0d8684bbc83375b032b976a6037 115 SUPERFAMILY SSF52821 4 105 7.73E-31 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS00375 2bc4e0d8684bbc83375b032b976a6037 115 Gene3D G3DSA:3.40.250.10 2 107 2.5E-26 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS00375 2bc4e0d8684bbc83375b032b976a6037 115 SMART SM00450 6 102 3.1E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS00375 2bc4e0d8684bbc83375b032b976a6037 115 Pfam PF00581 Rhodanese-like domain 21 98 6.7E-13 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS09850 9f5a20a07b05b5a2827045dc1e1f2dfc 304 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 93 5.7E-11 T 28-03-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 CNX65_RS09850 9f5a20a07b05b5a2827045dc1e1f2dfc 304 SUPERFAMILY SSF51735 1 104 3.21E-16 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09850 9f5a20a07b05b5a2827045dc1e1f2dfc 304 Gene3D G3DSA:3.40.50.720 2 174 9.7E-18 T 28-03-2018 CNX65_RS27000 0ff363fef6be0907d4eba9d819497ddb 255 SUPERFAMILY SSF161098 49 239 5.1E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS27000 0ff363fef6be0907d4eba9d819497ddb 255 Gene3D G3DSA:1.10.3720.10 3 248 4.5E-22 T 28-03-2018 CNX65_RS27000 0ff363fef6be0907d4eba9d819497ddb 255 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 232 9.9E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS20070 71ac5fdb0896852dd635806427131b32 174 SUPERFAMILY SSF53850 2 172 5.16E-15 T 28-03-2018 CNX65_RS20070 71ac5fdb0896852dd635806427131b32 174 Gene3D G3DSA:3.40.190.10 1 129 2.9E-14 T 28-03-2018 CNX65_RS29950 47db0f68161506e416a5dcffa6380069 122 Gene3D G3DSA:1.10.287.1060 1 66 0.59 T 28-03-2018 CNX65_RS29950 47db0f68161506e416a5dcffa6380069 122 Gene3D G3DSA:1.10.287.1060 67 122 0.0045 T 28-03-2018 CNX65_RS33205 57424db1c213be5ab5281066b05e9c7c 294 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 43 232 1.4E-16 T 28-03-2018 CNX65_RS33205 57424db1c213be5ab5281066b05e9c7c 294 Pfam PF12710 haloacid dehalogenase-like hydrolase 44 230 7.2E-26 T 28-03-2018 CNX65_RS33205 57424db1c213be5ab5281066b05e9c7c 294 TIGRFAM TIGR01490 HAD-SF-IB-hyp1: HAD hydrolase, family IB 43 244 1.6E-54 T 28-03-2018 IPR006385 HAD-superfamily hydrolase, subfamily IB, SerB1-like CNX65_RS33205 57424db1c213be5ab5281066b05e9c7c 294 Gene3D G3DSA:3.40.50.1000 110 268 1.9E-22 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS33205 57424db1c213be5ab5281066b05e9c7c 294 SUPERFAMILY SSF56784 43 262 6.64E-29 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34720 529d1fde8905bca72da65faab58564ea 680 Pfam PF05787 Bacterial protein of unknown function (DUF839) 90 637 3.0E-169 T 28-03-2018 IPR008557 Protein of unknown function DUF839 CNX65_RS34720 529d1fde8905bca72da65faab58564ea 680 SUPERFAMILY SSF63829 561 588 1.5E-7 T 28-03-2018 CNX65_RS34720 529d1fde8905bca72da65faab58564ea 680 SUPERFAMILY SSF63829 322 443 1.5E-7 T 28-03-2018 CNX65_RS34720 529d1fde8905bca72da65faab58564ea 680 Gene3D G3DSA:2.120.10.30 122 673 7.0E-6 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS29455 da4064b0aa84ba3e7a311eed18d4082f 60 Pfam PF04149 Domain of unknown function (DUF397) 6 57 1.3E-16 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS03335 be4bf606957b646824d214e6c8306b63 121 Pfam PF04977 Septum formation initiator 12 85 3.1E-14 T 28-03-2018 IPR007060 Septum formation initiator FtsL/DivIC GO:0007049 CNX65_RS00400 d08dc2b43698601797cdc2c77b4feb79 314 Gene3D G3DSA:3.10.450.50 2 36 4.9E-7 T 28-03-2018 CNX65_RS00400 d08dc2b43698601797cdc2c77b4feb79 314 Pfam PF02810 SEC-C motif 19 34 7.8E-7 T 28-03-2018 IPR004027 SEC-C motif CNX65_RS00400 d08dc2b43698601797cdc2c77b4feb79 314 SUPERFAMILY SSF103642 15 34 2.13E-6 T 28-03-2018 CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 Pfam PF00069 Protein kinase domain 11 264 1.5E-51 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 134 146 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 Pfam PF03793 PASTA domain 471 535 6.5E-11 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 Pfam PF03793 PASTA domain 395 465 1.3E-9 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 Pfam PF03793 PASTA domain 604 668 6.0E-9 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 Pfam PF03793 PASTA domain 540 600 1.0E-9 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 SMART SM00740 536 600 6.8E-12 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 SMART SM00740 467 535 1.9E-12 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 SMART SM00740 391 466 2.3E-9 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 SMART SM00740 601 669 3.5E-4 T 28-03-2018 IPR005543 PASTA domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 SUPERFAMILY SSF56112 8 276 7.01E-77 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 SMART SM00220 11 274 5.8E-66 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 Gene3D G3DSA:3.30.200.20 2 102 1.8E-23 T 28-03-2018 CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS00110 4947ed25e7655461562e112221f89c6b 681 Gene3D G3DSA:1.10.510.10 103 372 2.9E-52 T 28-03-2018 CNX65_RS01420 0aac35ef9a97f1b73edab7e202d21020 357 Pfam PF10935 Protein of unknown function (DUF2637) 72 227 1.3E-6 T 28-03-2018 IPR021235 Protein of unknown function DUF2637 CNX65_RS08100 6e6a6e8d16c10a9885d4dcf584fcddf6 386 Pfam PF01757 Acyltransferase family 43 368 1.1E-26 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS26805 37dd6fecf07cae024b47fd2886b63928 93 Pfam PF05488 PAAR motif 7 83 6.5E-21 T 28-03-2018 IPR008727 PAAR motif CNX65_RS10140 4cb262d814e10cb8de7f63adde996169 195 Gene3D G3DSA:2.60.120.180 33 133 0.0012 T 28-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CNX65_RS02085 802601f2654e41355dfb435709a3a54a 254 SUPERFAMILY SSF53213 1 254 1.44E-79 T 28-03-2018 CNX65_RS02085 802601f2654e41355dfb435709a3a54a 254 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 25 239 9.8E-37 T 28-03-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 CNX65_RS02085 802601f2654e41355dfb435709a3a54a 254 PIRSF PIRSF006157 1 254 5.9E-79 T 28-03-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 CNX65_RS02085 802601f2654e41355dfb435709a3a54a 254 Gene3D G3DSA:3.40.830.10 1 254 6.1E-75 T 28-03-2018 CNX65_RS01125 2114a763f7b6f4d8863c32d4404ab25f 330 Pfam PF02374 Anion-transporting ATPase 15 173 1.2E-19 T 28-03-2018 IPR025723 Anion-transporting ATPase-like domain Reactome: R-HSA-381038 CNX65_RS01125 2114a763f7b6f4d8863c32d4404ab25f 330 Gene3D G3DSA:3.40.50.300 8 330 4.7E-47 T 28-03-2018 CNX65_RS01125 2114a763f7b6f4d8863c32d4404ab25f 330 SUPERFAMILY SSF52540 13 234 1.56E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 Gene3D G3DSA:1.20.1250.20 264 520 1.7E-33 T 28-03-2018 CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 116 136 6.3E-11 T 28-03-2018 CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 25 49 6.3E-11 T 28-03-2018 CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 146 170 6.3E-11 T 28-03-2018 CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 PRINTS PR01036 Tetracycline resistance protein TetB signature 413 432 6.3E-11 T 28-03-2018 CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 Gene3D G3DSA:1.20.1250.20 14 211 7.1E-32 T 28-03-2018 CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 SUPERFAMILY SSF103473 260 432 6.28E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 SUPERFAMILY SSF103473 481 508 6.28E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 SUPERFAMILY SSF103473 15 206 6.28E-65 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS19755 79927eaa83b23847ae73fbb8151cbc5d 524 Pfam PF07690 Major Facilitator Superfamily 26 422 2.8E-46 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS26310 fc0ab74884cbf716fe83b01be817fc1c 281 SUPERFAMILY SSF56300 6 132 6.99E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS26310 fc0ab74884cbf716fe83b01be817fc1c 281 SUPERFAMILY SSF56300 172 263 6.99E-24 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS26310 fc0ab74884cbf716fe83b01be817fc1c 281 Pfam PF00149 Calcineurin-like phosphoesterase 6 240 8.7E-14 T 28-03-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 CNX65_RS26310 fc0ab74884cbf716fe83b01be817fc1c 281 Gene3D G3DSA:3.60.21.10 1 260 1.3E-22 T 28-03-2018 IPR029052 Metallo-dependent phosphatase-like CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 Gene3D G3DSA:3.50.50.60 4 131 1.6E-10 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 163 181 2.9E-10 T 28-03-2018 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 2.9E-10 T 28-03-2018 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 103 121 2.9E-10 T 28-03-2018 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 2.9E-10 T 28-03-2018 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 332 4.4E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 Gene3D G3DSA:3.50.50.60 132 342 8.8E-33 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 SUPERFAMILY SSF51905 95 343 1.63E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS09040 d19b6fead25192ad1e338844c47ad7be 442 SUPERFAMILY SSF51905 5 68 1.63E-25 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS28070 719e1158c1bbccdb0f1266a7b0f3c60a 145 Pfam PF05239 PRC-barrel domain 8 73 1.3E-10 T 28-03-2018 IPR027275 PRC-barrel domain CNX65_RS28070 719e1158c1bbccdb0f1266a7b0f3c60a 145 SUPERFAMILY SSF50346 6 114 1.18E-17 T 28-03-2018 IPR011033 PRC-barrel-like CNX65_RS28070 719e1158c1bbccdb0f1266a7b0f3c60a 145 Gene3D G3DSA:3.90.50.10 2 116 9.7E-19 T 28-03-2018 CNX65_RS13290 eec72232f405b0fd7d77d6f669e28bb7 320 SUPERFAMILY SSF53590 1 317 1.31E-88 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CNX65_RS13290 eec72232f405b0fd7d77d6f669e28bb7 320 Gene3D G3DSA:3.90.245.10 1 319 2.0E-98 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CNX65_RS13290 eec72232f405b0fd7d77d6f669e28bb7 320 Pfam PF01156 Inosine-uridine preferring nucleoside hydrolase 2 309 6.3E-80 T 28-03-2018 IPR001910 Inosine/uridine-preferring nucleoside hydrolase domain CNX65_RS18005 85e72a8d474d91194b83a1df01149983 540 Gene3D G3DSA:3.40.50.980 203 352 6.8E-31 T 28-03-2018 CNX65_RS18005 85e72a8d474d91194b83a1df01149983 540 Gene3D G3DSA:2.30.38.10 353 431 2.5E-16 T 28-03-2018 CNX65_RS18005 85e72a8d474d91194b83a1df01149983 540 Gene3D G3DSA:3.30.300.30 432 540 1.8E-22 T 28-03-2018 CNX65_RS18005 85e72a8d474d91194b83a1df01149983 540 Pfam PF00501 AMP-binding enzyme 71 435 2.3E-68 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS18005 85e72a8d474d91194b83a1df01149983 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 448 528 3.7E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS18005 85e72a8d474d91194b83a1df01149983 540 Gene3D G3DSA:3.40.50.980 53 202 2.0E-31 T 28-03-2018 CNX65_RS18005 85e72a8d474d91194b83a1df01149983 540 SUPERFAMILY SSF56801 54 538 1.01E-114 T 28-03-2018 CNX65_RS18120 5abb2dff61a1bf08c7419d26e4aaab26 773 Pfam PF04738 Lantibiotic dehydratase, C terminus 85 720 5.3E-82 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CNX65_RS11665 3367dd92b7c5fa456ced4ab78ccfbd84 357 Pfam PF02361 Cobalt transport protein 5 219 9.5E-7 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CNX65_RS20885 d98b10160595600cf50630ddb07d68de 249 Pfam PF09339 IclR helix-turn-helix domain 7 57 5.3E-12 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS20885 d98b10160595600cf50630ddb07d68de 249 Pfam PF01614 Bacterial transcriptional regulator 124 241 7.5E-14 T 28-03-2018 IPR014757 Transcription regulator IclR, C-terminal CNX65_RS20885 d98b10160595600cf50630ddb07d68de 249 SUPERFAMILY SSF46785 7 78 1.8E-15 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20885 d98b10160595600cf50630ddb07d68de 249 SMART SM00346 5 95 2.1E-9 T 28-03-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 CNX65_RS20885 d98b10160595600cf50630ddb07d68de 249 Gene3D G3DSA:3.30.450.40 71 247 5.0E-34 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS20885 d98b10160595600cf50630ddb07d68de 249 SUPERFAMILY SSF55781 63 245 5.1E-32 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS20885 d98b10160595600cf50630ddb07d68de 249 Gene3D G3DSA:1.10.10.10 4 67 2.9E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19140 d5bbb18db1d7fe17a0b790c3fe268079 264 Pfam PF08241 Methyltransferase domain 48 136 7.4E-14 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS19140 d5bbb18db1d7fe17a0b790c3fe268079 264 Gene3D G3DSA:3.40.50.150 8 264 1.9E-25 T 28-03-2018 CNX65_RS19140 d5bbb18db1d7fe17a0b790c3fe268079 264 SUPERFAMILY SSF53335 6 199 2.32E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS18870 9e69de086b22f5c7dc6f9f765dd04e70 395 Gene3D G3DSA:2.80.10.50 256 395 7.2E-27 T 28-03-2018 CNX65_RS18870 9e69de086b22f5c7dc6f9f765dd04e70 395 Pfam PF00652 Ricin-type beta-trefoil lectin domain 266 348 1.0E-7 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS18870 9e69de086b22f5c7dc6f9f765dd04e70 395 Gene3D G3DSA:2.60.40.10 134 227 0.33 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS18870 9e69de086b22f5c7dc6f9f765dd04e70 395 SUPERFAMILY SSF50370 265 394 7.68E-24 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS18870 9e69de086b22f5c7dc6f9f765dd04e70 395 SUPERFAMILY SSF117074 22 104 2.48E-8 T 28-03-2018 CNX65_RS18870 9e69de086b22f5c7dc6f9f765dd04e70 395 SMART SM00458 263 395 4.3E-6 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS18870 9e69de086b22f5c7dc6f9f765dd04e70 395 Gene3D G3DSA:2.60.40.1120 26 132 4.4E-10 T 28-03-2018 CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 27 139 3.3E-25 T 28-03-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 Gene3D G3DSA:3.90.180.10 3 172 2.9E-48 T 28-03-2018 CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 Pfam PF00107 Zinc-binding dehydrogenase 182 303 8.9E-16 T 28-03-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 SUPERFAMILY SSF50129 12 168 2.99E-44 T 28-03-2018 IPR011032 GroES-like CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 58 72 - T 28-03-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 Gene3D G3DSA:3.40.50.720 173 336 1.2E-21 T 28-03-2018 CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 SMART SM00829 11 337 1.4E-5 T 28-03-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 CNX65_RS24790 c21f5107dac448190a440ea8a3425b8d 343 SUPERFAMILY SSF51735 145 307 2.86E-37 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS17200 d58330eaa2652c9ebb4ea3f4a4df3185 158 SUPERFAMILY SSF50370 21 156 1.15E-9 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS17200 d58330eaa2652c9ebb4ea3f4a4df3185 158 Gene3D G3DSA:2.80.10.50 18 158 2.4E-9 T 28-03-2018 CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 ProSitePatterns PS00018 EF-hand calcium-binding domain. 14 26 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 ProSitePatterns PS00018 EF-hand calcium-binding domain. 64 76 - T 28-03-2018 IPR018247 EF-Hand 1, calcium-binding site CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 SMART SM00054 93 121 27.0 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 SMART SM00054 55 83 2.8 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 SMART SM00054 5 33 17.0 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 SUPERFAMILY SSF47473 5 163 1.87E-19 T 28-03-2018 IPR011992 EF-hand domain pair CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 Gene3D G3DSA:1.10.238.10 68 108 3.4E-6 T 28-03-2018 CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 Gene3D G3DSA:1.10.238.10 4 67 5.8E-9 T 28-03-2018 CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 Pfam PF13499 EF-hand domain pair 9 77 3.7E-7 T 28-03-2018 IPR002048 EF-hand domain GO:0005509 CNX65_RS23645 655b839366a34a21f2497d185928afeb 175 Gene3D G3DSA:1.10.238.10 109 161 1.6E-4 T 28-03-2018 CNX65_RS05190 7254b7ccca7155364230018ffd743b24 394 Pfam PF08245 Mur ligase middle domain 42 246 2.6E-17 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS05190 7254b7ccca7155364230018ffd743b24 394 SUPERFAMILY SSF53623 27 263 4.27E-34 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS05190 7254b7ccca7155364230018ffd743b24 394 Pfam PF08353 Domain of unknown function (DUF1727) 284 383 2.4E-26 T 28-03-2018 IPR013564 Domain of unknown function DUF1727 CNX65_RS05190 7254b7ccca7155364230018ffd743b24 394 Gene3D G3DSA:3.40.1190.10 35 270 1.3E-41 T 28-03-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 Reactome: R-HSA-196757 CNX65_RS16175 5c9eb538453d01b5707a908c33602201 170 SMART SM00823 Phosphopantetheine attachment site 89 161 1.6E-22 T 28-03-2018 IPR020806 Polyketide synthase, phosphopantetheine-binding domain GO:0031177 Reactome: R-HSA-163765|Reactome: R-HSA-199220|Reactome: R-HSA-2426168|Reactome: R-HSA-75105 CNX65_RS16175 5c9eb538453d01b5707a908c33602201 170 Pfam PF00550 Phosphopantetheine attachment site 92 157 7.3E-12 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16175 5c9eb538453d01b5707a908c33602201 170 SUPERFAMILY SSF47336 85 164 7.33E-20 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS16175 5c9eb538453d01b5707a908c33602201 170 Gene3D G3DSA:1.10.1200.10 37 169 3.7E-20 T 28-03-2018 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 Gene3D G3DSA:3.40.50.2300 7 139 2.1E-36 T 28-03-2018 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 SUPERFAMILY SSF46894 151 222 2.79E-22 T 28-03-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 SMART SM00421 158 215 1.7E-24 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 Gene3D G3DSA:1.10.10.10 140 219 4.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 Pfam PF00196 Bacterial regulatory proteins, luxR family 160 215 5.7E-18 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 175 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 175 191 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 191 203 5.8E-14 T 28-03-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 Pfam PF00072 Response regulator receiver domain 10 121 2.5E-27 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 SUPERFAMILY SSF52172 7 140 2.28E-32 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS20275 cc15d75e37384742b35f33adf78c016e 225 SMART SM00448 8 121 3.9E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS34850 2b3c68faa09f57ac4c8f83eb10e8ab69 401 Pfam PF01594 AI-2E family transporter 26 347 1.2E-62 T 28-03-2018 IPR002549 Transmembrane protein TqsA-like CNX65_RS16915 8db64db292705a5c0249ef12169f1d6a 286 Pfam PF13714 Phosphoenolpyruvate phosphomutase 9 253 4.5E-63 T 28-03-2018 CNX65_RS16915 8db64db292705a5c0249ef12169f1d6a 286 Gene3D G3DSA:3.20.20.60 1 286 1.3E-70 T 28-03-2018 CNX65_RS16915 8db64db292705a5c0249ef12169f1d6a 286 SUPERFAMILY SSF51621 6 284 2.96E-73 T 28-03-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain GO:0003824 CNX65_RS32480 0d583363a228a02de53d045df7c5693e 210 Gene3D G3DSA:3.30.1310.10 18 117 2.1E-19 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS32480 0d583363a228a02de53d045df7c5693e 210 SUPERFAMILY SSF82607 22 110 2.62E-7 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS32480 0d583363a228a02de53d045df7c5693e 210 Pfam PF02575 YbaB/EbfC DNA-binding family 25 112 7.9E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS04695 1622ead730b98ba61a6e31fda981f339 382 Pfam PF00535 Glycosyl transferase family 2 57 187 1.0E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS04695 1622ead730b98ba61a6e31fda981f339 382 Gene3D G3DSA:3.90.550.10 31 285 5.4E-42 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS04695 1622ead730b98ba61a6e31fda981f339 382 SUPERFAMILY SSF53448 52 270 2.15E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS04250 c74e01253d2f2578c18d7b741dcd9916 187 SUPERFAMILY SSF160904 2 162 2.88E-34 T 28-03-2018 CNX65_RS04250 c74e01253d2f2578c18d7b741dcd9916 187 Pfam PF07336 Putative stress-induced transcription regulator 7 113 7.1E-6 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator CNX65_RS04250 c74e01253d2f2578c18d7b741dcd9916 187 Gene3D G3DSA:1.10.3300.10 1 165 1.1E-29 T 28-03-2018 IPR023286 ABATE domain CNX65_RS04250 c74e01253d2f2578c18d7b741dcd9916 187 Pfam PF11706 CGNR zinc finger 120 163 6.5E-16 T 28-03-2018 IPR021005 Zinc finger, CGNR CNX65_RS21935 72a8b9016dfd8c2262bdcb3623f428bf 572 Gene3D G3DSA:1.10.600.10 226 572 1.3E-82 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS21935 72a8b9016dfd8c2262bdcb3623f428bf 572 SUPERFAMILY SSF48576 251 571 2.56E-76 T 28-03-2018 IPR008949 Isoprenoid synthase domain CNX65_RS21935 72a8b9016dfd8c2262bdcb3623f428bf 572 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 321 335 - T 28-03-2018 IPR033749 Polyprenyl synthetase, conserved site CNX65_RS21935 72a8b9016dfd8c2262bdcb3623f428bf 572 Pfam PF00348 Polyprenyl synthetase 274 510 3.2E-51 T 28-03-2018 IPR000092 Polyprenyl synthetase GO:0008299 CNX65_RS08650 1e0691e9752f646c0a4432998d6004ed 322 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 244 2.7E-50 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS08650 1e0691e9752f646c0a4432998d6004ed 322 Gene3D G3DSA:3.40.50.720 5 174 7.2E-36 T 28-03-2018 CNX65_RS08650 1e0691e9752f646c0a4432998d6004ed 322 Gene3D G3DSA:3.90.25.10 175 322 8.7E-38 T 28-03-2018 CNX65_RS08650 1e0691e9752f646c0a4432998d6004ed 322 SUPERFAMILY SSF51735 3 317 6.85E-82 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS07045 63aa9360068fc713449b31189044b048 212 TIGRFAM TIGR01182 eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase 11 210 4.0E-72 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CNX65_RS07045 63aa9360068fc713449b31189044b048 212 SUPERFAMILY SSF51569 9 210 1.45E-64 T 28-03-2018 CNX65_RS07045 63aa9360068fc713449b31189044b048 212 ProSitePatterns PS00159 KDPG and KHG aldolases active site. 41 50 - T 28-03-2018 IPR031337 KDPG/KHG aldolase, active site 1 KEGG: 00030+4.1.2.14|KEGG: 00330+4.1.3.16|KEGG: 00630+4.1.3.16|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CNX65_RS07045 63aa9360068fc713449b31189044b048 212 Gene3D G3DSA:3.20.20.70 7 212 1.2E-31 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS07045 63aa9360068fc713449b31189044b048 212 ProSitePatterns PS00160 KDPG and KHG aldolases Schiff-base forming residue. 129 142 - T 28-03-2018 IPR031338 KDPG/KHG aldolase, active site 2 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CNX65_RS07045 63aa9360068fc713449b31189044b048 212 Pfam PF01081 KDPG and KHG aldolase 13 203 6.3E-65 T 28-03-2018 IPR000887 KDPG/KHG aldolase GO:0008152|GO:0016829 KEGG: 00030+4.1.2.14|MetaCyc: PWY-2221|MetaCyc: PWY-6507|MetaCyc: PWY-7242|MetaCyc: PWY-7310|MetaCyc: PWY-7562 CNX65_RS25205 7f6b13bcfdde6015418b63d16f9c9591 414 Gene3D G3DSA:1.10.150.130 73 178 1.8E-17 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS25205 7f6b13bcfdde6015418b63d16f9c9591 414 SUPERFAMILY SSF56349 80 378 4.12E-55 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS25205 7f6b13bcfdde6015418b63d16f9c9591 414 Pfam PF00589 Phage integrase family 186 372 2.3E-22 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS25205 7f6b13bcfdde6015418b63d16f9c9591 414 Gene3D G3DSA:1.10.443.10 179 387 2.4E-36 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS25455 fd053f4eb8c7741a5066ef1a53518b6e 347 Gene3D G3DSA:3.40.1190.20 9 319 1.3E-50 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS25455 fd053f4eb8c7741a5066ef1a53518b6e 347 Pfam PF00294 pfkB family carbohydrate kinase 44 295 1.3E-25 T 28-03-2018 IPR011611 Carbohydrate kinase PfkB CNX65_RS25455 fd053f4eb8c7741a5066ef1a53518b6e 347 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 248 261 - T 28-03-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 CNX65_RS25455 fd053f4eb8c7741a5066ef1a53518b6e 347 SUPERFAMILY SSF53613 10 298 2.49E-49 T 28-03-2018 IPR029056 Ribokinase-like CNX65_RS04865 6e1900f9da303ab48aa398d73ede4814 120 Gene3D G3DSA:3.30.750.24 4 120 6.0E-13 T 28-03-2018 IPR002645 STAS domain CNX65_RS04865 6e1900f9da303ab48aa398d73ede4814 120 Pfam PF13466 STAS domain 28 104 1.4E-10 T 28-03-2018 IPR002645 STAS domain CNX65_RS04865 6e1900f9da303ab48aa398d73ede4814 120 SUPERFAMILY SSF52091 16 119 2.35E-15 T 28-03-2018 IPR002645 STAS domain CNX65_RS25060 e933db56a1e1b4533b400f4bdc77353d 1241 Pfam PF10145 Phage-related minor tail protein 89 288 8.3E-41 T 28-03-2018 IPR010090 Phage tail tape measure protein CNX65_RS25060 e933db56a1e1b4533b400f4bdc77353d 1241 Gene3D G3DSA:1.20.5.1230 219 797 0.017 T 28-03-2018 CNX65_RS25060 e933db56a1e1b4533b400f4bdc77353d 1241 TIGRFAM TIGR01760 tape_meas_TP901: phage tail tape measure protein, TP901 family, core region 51 370 1.4E-51 T 28-03-2018 IPR010090 Phage tail tape measure protein CNX65_RS13435 183473d078502f9832a3267344958eba 257 Gene3D G3DSA:3.20.20.70 5 255 3.1E-68 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS13435 183473d078502f9832a3267344958eba 257 Pfam PF00121 Triosephosphate isomerase 10 238 2.3E-46 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS13435 183473d078502f9832a3267344958eba 257 SUPERFAMILY SSF51351 7 248 1.03E-56 T 28-03-2018 IPR000652 Triosephosphate isomerase GO:0004807|GO:0008152 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 CNX65_RS33015 30f21f1d4aac845ff79642e00883b028 353 SUPERFAMILY SSF56801 31 351 8.37E-64 T 28-03-2018 CNX65_RS33015 30f21f1d4aac845ff79642e00883b028 353 Pfam PF00501 AMP-binding enzyme 32 254 6.0E-27 T 28-03-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824|GO:0008152 CNX65_RS33015 30f21f1d4aac845ff79642e00883b028 353 Gene3D G3DSA:3.40.50.980 26 190 3.1E-23 T 28-03-2018 CNX65_RS33015 30f21f1d4aac845ff79642e00883b028 353 Gene3D G3DSA:2.30.38.10 191 247 6.4E-6 T 28-03-2018 CNX65_RS33015 30f21f1d4aac845ff79642e00883b028 353 Gene3D G3DSA:3.30.300.30 248 352 7.2E-23 T 28-03-2018 CNX65_RS33015 30f21f1d4aac845ff79642e00883b028 353 Pfam PF13193 AMP-binding enzyme C-terminal domain 264 339 4.5E-16 T 28-03-2018 IPR025110 AMP-binding enzyme, C-terminal domain CNX65_RS11965 bb1e1021a63563f932fed1fb79d79d6a 118 Pfam PF00460 Flagella basal body rod protein 13 36 1.5E-4 T 28-03-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 CNX65_RS11965 bb1e1021a63563f932fed1fb79d79d6a 118 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 10 116 6.5E-21 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CNX65_RS11965 bb1e1021a63563f932fed1fb79d79d6a 118 PIRSF PIRSF002889 3 118 6.1E-20 T 28-03-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 CNX65_RS00595 19ffefb193114b1fa42a59c15117cfaa 124 Pfam PF14219 Domain of unknown function (DUF4328) 3 85 6.2E-15 T 28-03-2018 IPR025565 Domain of unknown function DUF4328 CNX65_RS28130 2b906936873a2316da6b28ecb4186a5d 81 Pfam PF00462 Glutaredoxin 4 62 7.1E-14 T 28-03-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 CNX65_RS28130 2b906936873a2316da6b28ecb4186a5d 81 Gene3D G3DSA:3.40.30.10 2 80 1.1E-16 T 28-03-2018 CNX65_RS28130 2b906936873a2316da6b28ecb4186a5d 81 SUPERFAMILY SSF52833 4 66 5.6E-15 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS19100 9225cf9cf5676c29e20de333b4cfd3de 326 SUPERFAMILY SSF51430 3 318 1.7E-100 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS19100 9225cf9cf5676c29e20de333b4cfd3de 326 Pfam PF00248 Aldo/keto reductase family 15 315 8.1E-76 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS19100 9225cf9cf5676c29e20de333b4cfd3de 326 PRINTS PR00069 Aldo-keto reductase signature 47 71 4.2E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19100 9225cf9cf5676c29e20de333b4cfd3de 326 PRINTS PR00069 Aldo-keto reductase signature 113 131 4.2E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19100 9225cf9cf5676c29e20de333b4cfd3de 326 PRINTS PR00069 Aldo-keto reductase signature 144 161 4.2E-5 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS19100 9225cf9cf5676c29e20de333b4cfd3de 326 Gene3D G3DSA:3.20.20.100 3 320 4.7E-98 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 PIRSF PIRSF001365 4 306 1.9E-68 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 SMART SM01130 7 298 1.4E-91 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 47 68 1.1E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 115 131 1.1E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 PRINTS PR00146 Dihydrodipicolinate synthase signature 139 156 1.1E-6 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 Pfam PF00701 Dihydrodipicolinate synthetase family 9 294 1.3E-46 T 28-03-2018 IPR002220 DapA-like GO:0008152|GO:0016829 CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 Gene3D G3DSA:3.20.20.70 1 309 2.2E-81 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS23510 a3020b350524f876c46c9556b210b374 310 SUPERFAMILY SSF51569 6 296 1.78E-78 T 28-03-2018 CNX65_RS04425 69a81f36d17acb9275a05c56a3f1818d 247 Pfam PF13476 AAA domain 35 70 2.5E-7 T 28-03-2018 CNX65_RS04425 69a81f36d17acb9275a05c56a3f1818d 247 Gene3D G3DSA:3.40.50.300 27 228 4.8E-22 T 28-03-2018 CNX65_RS04425 69a81f36d17acb9275a05c56a3f1818d 247 SUPERFAMILY SSF52540 35 213 6.82E-21 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04425 69a81f36d17acb9275a05c56a3f1818d 247 SMART SM00382 38 216 1.2E-7 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 Pfam PF12802 MarR family 37 98 5.7E-15 T 28-03-2018 CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 SUPERFAMILY SSF46785 6 147 2.26E-29 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 SMART SM00347 32 135 8.1E-17 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 125 145 3.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 94 110 3.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 58 74 3.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 PRINTS PR00598 Bacterial regulatory protein MarR family signature 75 90 3.6E-7 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS11560 8e29e48622979fb5112b31fd8d182f6a 166 Gene3D G3DSA:1.10.10.10 4 156 1.5E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS27505 f83eccf105875372ba68bb2edf55876b 276 SUPERFAMILY SSF53335 32 255 3.19E-38 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS27505 f83eccf105875372ba68bb2edf55876b 276 Pfam PF08241 Methyltransferase domain 79 171 5.5E-19 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS27505 f83eccf105875372ba68bb2edf55876b 276 Gene3D G3DSA:3.40.50.150 20 255 2.7E-30 T 28-03-2018 CNX65_RS10110 3fc15c58c8c19145ba4d6efae7429537 380 Pfam PF12307 Protein of unknown function (DUF3631) 170 349 1.9E-63 T 28-03-2018 IPR022081 Domain of unknown function DUF3631 CNX65_RS07145 a5dabf43927a2025eac7be7acc59dcbc 448 Pfam PF03993 Domain of Unknown Function (DUF349) 290 363 5.9E-21 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CNX65_RS07145 a5dabf43927a2025eac7be7acc59dcbc 448 Pfam PF03993 Domain of Unknown Function (DUF349) 136 209 9.6E-13 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CNX65_RS07145 a5dabf43927a2025eac7be7acc59dcbc 448 Pfam PF03993 Domain of Unknown Function (DUF349) 214 286 1.6E-20 T 28-03-2018 IPR007139 Protein of unknown function DUF349 CNX65_RS15645 6b1528c20ad3e58c0377b780d308cdca 426 Gene3D G3DSA:3.40.710.10 64 415 3.9E-52 T 28-03-2018 CNX65_RS15645 6b1528c20ad3e58c0377b780d308cdca 426 Pfam PF00144 Beta-lactamase 69 402 2.3E-37 T 28-03-2018 IPR001466 Beta-lactamase-related CNX65_RS15645 6b1528c20ad3e58c0377b780d308cdca 426 SUPERFAMILY SSF56601 67 406 6.12E-49 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS31355 91e1a4b5dd7d552e08fe8948326304e4 102 SUPERFAMILY SSF140453 4 100 4.58E-5 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS31355 91e1a4b5dd7d552e08fe8948326304e4 102 Gene3D G3DSA:1.10.287.1060 1 102 6.1E-13 T 28-03-2018 CNX65_RS32370 7432b5b4344323ff907d2b76ff7aff18 132 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 18 132 1.9E-47 T 28-03-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32370 7432b5b4344323ff907d2b76ff7aff18 132 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 18 132 27.124 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32370 7432b5b4344323ff907d2b76ff7aff18 132 SUPERFAMILY SSF53137 19 130 1.31E-46 T 28-03-2018 CNX65_RS32370 7432b5b4344323ff907d2b76ff7aff18 132 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 21 132 4.2E-39 T 28-03-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 CNX65_RS32370 7432b5b4344323ff907d2b76ff7aff18 132 Gene3D G3DSA:3.30.420.100 14 132 1.1E-39 T 28-03-2018 CNX65_RS21385 9131f5fc8612604be12cbd6e48a98c62 224 SUPERFAMILY SSF51219 20 217 1.12E-45 T 28-03-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain CNX65_RS21385 9131f5fc8612604be12cbd6e48a98c62 224 Gene3D G3DSA:3.60.160.10 13 220 2.0E-45 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CNX65_RS21385 9131f5fc8612604be12cbd6e48a98c62 224 Pfam PF01987 Mitochondrial biogenesis AIM24 18 213 3.0E-31 T 28-03-2018 IPR002838 Mitochondrial biogenesis protein AIM24 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 Gene3D G3DSA:1.10.1040.10 502 608 8.8E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 503 603 4.4E-18 T 28-03-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 SUPERFAMILY SSF51735 320 501 4.03E-56 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 Gene3D G3DSA:3.40.50.720 260 501 8.0E-63 T 28-03-2018 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 Gene3D G3DSA:3.90.226.10 1 209 1.2E-49 T 28-03-2018 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 206 1.8E-34 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 Gene3D G3DSA:1.10.1040.10 630 720 6.0E-14 T 28-03-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 322 500 8.5E-62 T 28-03-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779|MetaCyc: PWY-81 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 SUPERFAMILY SSF52096 3 306 1.07E-60 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 SUPERFAMILY SSF48179 630 720 1.53E-15 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS21875 8801b9ad0dc7ef1f6764776eedf622c2 721 SUPERFAMILY SSF48179 502 643 6.63E-17 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS33215 be2e44dfec511616b83d2ee99f599b4a 345 Gene3D G3DSA:3.40.50.720 1 321 6.8E-36 T 28-03-2018 CNX65_RS33215 be2e44dfec511616b83d2ee99f599b4a 345 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 235 7.4E-21 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS33215 be2e44dfec511616b83d2ee99f599b4a 345 SUPERFAMILY SSF51735 1 317 5.13E-41 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22290 8f3a0b387bf2f15e761091904eb8c4d6 573 Pfam PF00069 Protein kinase domain 15 231 6.6E-44 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS22290 8f3a0b387bf2f15e761091904eb8c4d6 573 SMART SM00220 15 275 2.1E-49 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS22290 8f3a0b387bf2f15e761091904eb8c4d6 573 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 21 44 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS22290 8f3a0b387bf2f15e761091904eb8c4d6 573 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 143 155 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS22290 8f3a0b387bf2f15e761091904eb8c4d6 573 Gene3D G3DSA:3.30.200.20 1 105 2.9E-22 T 28-03-2018 CNX65_RS22290 8f3a0b387bf2f15e761091904eb8c4d6 573 SUPERFAMILY SSF56112 7 270 7.28E-62 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS22290 8f3a0b387bf2f15e761091904eb8c4d6 573 Gene3D G3DSA:1.10.510.10 106 340 4.6E-41 T 28-03-2018 CNX65_RS32360 61f6bed430c34f08ace6871d0c4f4db0 61 SUPERFAMILY SSF55129 1 59 7.72E-21 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CNX65_RS32360 61f6bed430c34f08ace6871d0c4f4db0 61 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 1 58 20.319 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32360 61f6bed430c34f08ace6871d0c4f4db0 61 PIRSF PIRSF002211 1 60 5.6E-27 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS32360 61f6bed430c34f08ace6871d0c4f4db0 61 Gene3D G3DSA:3.30.1390.20 4 58 1.6E-22 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CNX65_RS32360 61f6bed430c34f08ace6871d0c4f4db0 61 Pfam PF00327 Ribosomal protein L30p/L7e 4 54 7.7E-18 T 28-03-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain CNX65_RS32360 61f6bed430c34f08ace6871d0c4f4db0 61 ProSitePatterns PS00634 Ribosomal protein L30 signature. 22 54 - T 28-03-2018 IPR018038 Ribosomal protein L30, conserved site CNX65_RS32360 61f6bed430c34f08ace6871d0c4f4db0 61 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 4 58 9.3E-23 T 28-03-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS01260 6a3d3aa94d617dbafbba5353fe5edd20 273 SUPERFAMILY SSF140959 18 272 1.26E-76 T 28-03-2018 CNX65_RS01260 6a3d3aa94d617dbafbba5353fe5edd20 273 Hamap MF_01972 Tryptophan 2,3-dioxygenase [kynA]. 12 273 35.523 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CNX65_RS01260 6a3d3aa94d617dbafbba5353fe5edd20 273 Pfam PF03301 Tryptophan 2,3-dioxygenase 14 200 6.8E-34 T 28-03-2018 IPR004981 Tryptophan 2,3-dioxygenase GO:0004833|GO:0019441|GO:0020037 KEGG: 00380+1.13.11.11|Reactome: R-HSA-71240 CNX65_RS21910 142d6dae1be80bf87358c60516599e00 455 SUPERFAMILY SSF52540 33 121 6.59E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21910 142d6dae1be80bf87358c60516599e00 455 SUPERFAMILY SSF52540 238 341 6.59E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21910 142d6dae1be80bf87358c60516599e00 455 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 6 406 7.4E-161 T 28-03-2018 IPR021228 Protein of unknown function DUF2791 CNX65_RS21910 142d6dae1be80bf87358c60516599e00 455 Gene3D G3DSA:3.40.50.300 14 403 1.6E-4 T 28-03-2018 CNX65_RS22100 bb5e159bf45b583e8c86e02131c380bd 53 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 53 13.251 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS22100 bb5e159bf45b583e8c86e02131c380bd 53 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 31 1.7E-10 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS22100 bb5e159bf45b583e8c86e02131c380bd 53 SUPERFAMILY SSF57829 1 31 3.66E-8 T 28-03-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 CNX65_RS22100 bb5e159bf45b583e8c86e02131c380bd 53 Pfam PF01783 Ribosomal L32p protein family 2 45 4.2E-11 T 28-03-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 CNX65_RS06125 1065548b596fecad821cd511778de8c0 112 Pfam PF01337 Barstar (barnase inhibitor) 19 99 4.9E-21 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CNX65_RS06125 1065548b596fecad821cd511778de8c0 112 SUPERFAMILY SSF52038 18 101 2.62E-20 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CNX65_RS06125 1065548b596fecad821cd511778de8c0 112 Gene3D G3DSA:3.30.370.10 15 106 3.6E-21 T 28-03-2018 IPR000468 Barstar (barnase inhibitor) CNX65_RS30480 2201214103e8e4ccfc40ea5cd2bd7021 368 Pfam PF00296 Luciferase-like monooxygenase 39 267 8.3E-30 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS30480 2201214103e8e4ccfc40ea5cd2bd7021 368 SUPERFAMILY SSF51679 35 358 2.69E-60 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS30480 2201214103e8e4ccfc40ea5cd2bd7021 368 Gene3D G3DSA:3.20.20.30 267 368 2.0E-14 T 28-03-2018 CNX65_RS30480 2201214103e8e4ccfc40ea5cd2bd7021 368 Gene3D G3DSA:3.20.20.30 1 266 3.0E-41 T 28-03-2018 CNX65_RS30480 2201214103e8e4ccfc40ea5cd2bd7021 368 PIRSF PIRSF000337 267 366 1.7E-10 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CNX65_RS30480 2201214103e8e4ccfc40ea5cd2bd7021 368 PIRSF PIRSF000337 35 274 2.1E-46 T 28-03-2018 IPR016215 Nitrilotriacetate monooxygenase component A/pristinamycin IIA synthase subunit A GO:0004497 CNX65_RS10795 2eb9aeeaebf7d715a3ffffb0c87f5ca2 155 Gene3D G3DSA:3.10.129.10 3 148 4.0E-25 T 28-03-2018 CNX65_RS10795 2eb9aeeaebf7d715a3ffffb0c87f5ca2 155 SUPERFAMILY SSF54637 3 135 5.91E-31 T 28-03-2018 IPR029069 HotDog domain CNX65_RS10795 2eb9aeeaebf7d715a3ffffb0c87f5ca2 155 Pfam PF03061 Thioesterase superfamily 23 100 1.6E-8 T 28-03-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 CNX65_RS10795 2eb9aeeaebf7d715a3ffffb0c87f5ca2 155 PIRSF PIRSF003230 1 140 4.0E-20 T 28-03-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 CNX65_RS25660 f1fca0cf0458ed7a9df428b7993a7269 1299 Pfam PF11856 Protein of unknown function (DUF3376) 593 796 1.2E-17 T 28-03-2018 IPR024282 Domain of unknown function DUF3376 CNX65_RS25660 f1fca0cf0458ed7a9df428b7993a7269 1299 Gene3D G3DSA:3.40.1090.10 15 384 4.4E-26 T 28-03-2018 CNX65_RS25660 f1fca0cf0458ed7a9df428b7993a7269 1299 Pfam PF01734 Patatin-like phospholipase 26 285 3.9E-19 T 28-03-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 CNX65_RS25660 f1fca0cf0458ed7a9df428b7993a7269 1299 SUPERFAMILY SSF52151 218 295 3.92E-18 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS25660 f1fca0cf0458ed7a9df428b7993a7269 1299 SUPERFAMILY SSF52151 21 175 3.92E-18 T 28-03-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase GO:0008152 CNX65_RS25660 f1fca0cf0458ed7a9df428b7993a7269 1299 TIGRFAM TIGR03607 TIGR03607: patatin-related protein 21 721 1.8E-113 T 28-03-2018 IPR019894 Patatin-related protein CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 Gene3D G3DSA:3.40.800.20 8 354 6.6E-94 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 SUPERFAMILY SSF52768 10 341 6.23E-103 T 28-03-2018 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 PRINTS PR01272 Acetoin utilisation ACUC protein signature 109 122 2.6E-9 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 PRINTS PR01272 Acetoin utilisation ACUC protein signature 22 42 2.6E-9 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 PRINTS PR01272 Acetoin utilisation ACUC protein signature 88 102 2.6E-9 T 28-03-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 PRINTS PR01270 Histone deacetylase superfamily signature 165 180 1.5E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 PRINTS PR01270 Histone deacetylase superfamily signature 251 261 1.5E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 PRINTS PR01270 Histone deacetylase superfamily signature 132 155 1.5E-18 T 28-03-2018 IPR000286 Histone deacetylase superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS07280 bd883ee7386f9243728d9ed0d0874d70 397 Pfam PF00850 Histone deacetylase domain 28 321 1.7E-73 T 28-03-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 CNX65_RS09915 119e834d4276b0a043abcf20232340c9 120 PIRSF PIRSF016498 1 120 4.9E-18 T 28-03-2018 IPR018699 Protein of unknown function DUF2203 CNX65_RS09915 119e834d4276b0a043abcf20232340c9 120 Pfam PF09969 Uncharacterized conserved protein (DUF2203) 3 119 5.8E-31 T 28-03-2018 IPR018699 Protein of unknown function DUF2203 CNX65_RS26680 d2ec6e2f227fe6dbf7b3177daa19b432 203 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 60 82 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS26680 d2ec6e2f227fe6dbf7b3177daa19b432 203 Pfam PF01066 CDP-alcohol phosphatidyltransferase 18 82 1.1E-13 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS26680 d2ec6e2f227fe6dbf7b3177daa19b432 203 PIRSF PIRSF000847 13 198 4.5E-40 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CNX65_RS20710 d4fbf7af92577fd46ef5437da1a6f959 734 Gene3D G3DSA:1.10.150.20 544 624 0.004 T 28-03-2018 CNX65_RS20710 d4fbf7af92577fd46ef5437da1a6f959 734 SUPERFAMILY SSF56112 41 214 2.35E-15 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS20710 d4fbf7af92577fd46ef5437da1a6f959 734 Gene3D G3DSA:1.10.510.10 38 278 4.6E-13 T 28-03-2018 CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 Gene3D G3DSA:3.40.710.10 84 363 5.4E-51 T 28-03-2018 CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 PRINTS PR01217 Proline rich extensin signature 535 547 5.6E-9 T 28-03-2018 CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 PRINTS PR01217 Proline rich extensin signature 558 579 5.6E-9 T 28-03-2018 CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 PRINTS PR01217 Proline rich extensin signature 658 670 5.6E-9 T 28-03-2018 CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 PRINTS PR01217 Proline rich extensin signature 490 502 5.6E-9 T 28-03-2018 CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 PRINTS PR01217 Proline rich extensin signature 617 642 5.6E-9 T 28-03-2018 CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 SUPERFAMILY SSF56601 13 34 2.38E-53 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 SUPERFAMILY SSF56601 94 331 2.38E-53 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS31725 e0aac74930f047df80e97f964c2636ec 726 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 89 313 5.4E-39 T 28-03-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 CNX65_RS23740 cf42ad963fee03219a88bc71dd48c5c1 334 Gene3D G3DSA:3.40.50.1100 129 303 9.0E-25 T 28-03-2018 CNX65_RS23740 cf42ad963fee03219a88bc71dd48c5c1 334 Gene3D G3DSA:3.40.50.1100 28 128 1.1E-17 T 28-03-2018 CNX65_RS23740 cf42ad963fee03219a88bc71dd48c5c1 334 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 29 280 5.0E-31 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS23740 cf42ad963fee03219a88bc71dd48c5c1 334 SUPERFAMILY SSF53686 28 294 5.24E-46 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS31140 c0441a0092837f7580f02278f8167710 150 SUPERFAMILY SSF55486 36 148 4.39E-27 T 28-03-2018 CNX65_RS31140 c0441a0092837f7580f02278f8167710 150 Pfam PF06262 Zincin-like metallopeptidase 62 147 6.0E-12 T 28-03-2018 IPR010428 Zincin-like metallopeptidase CNX65_RS01245 c698ea5032efe780eeb130c435551dd3 193 SUPERFAMILY SSF55729 5 176 1.46E-38 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS01245 c698ea5032efe780eeb130c435551dd3 193 Pfam PF13302 Acetyltransferase (GNAT) domain 14 150 1.2E-15 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS01245 c698ea5032efe780eeb130c435551dd3 193 Gene3D G3DSA:3.40.630.30 2 184 7.4E-32 T 28-03-2018 CNX65_RS25705 1e926d6facd639779bc9b0c707a12acf 322 Pfam PF02628 Cytochrome oxidase assembly protein 18 286 9.7E-14 T 28-03-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 CNX65_RS24640 9312279ea11466f57e2c31ef0d51b479 452 Pfam PF00171 Aldehyde dehydrogenase family 25 343 9.6E-14 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS24640 9312279ea11466f57e2c31ef0d51b479 452 SUPERFAMILY SSF53720 22 437 4.77E-28 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS24640 9312279ea11466f57e2c31ef0d51b479 452 Gene3D G3DSA:3.40.605.10 18 270 2.9E-21 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS09370 9618f18be33ed57071c527fe52c12321 390 Pfam PF04231 Endonuclease I 173 383 6.9E-41 T 28-03-2018 IPR007346 Endonuclease I GO:0004518 CNX65_RS09370 9618f18be33ed57071c527fe52c12321 390 SUPERFAMILY SSF54060 171 383 1.41E-53 T 28-03-2018 CNX65_RS03150 c3d6e915665c8a859bff252890819f3b 523 Pfam PF02366 Dolichyl-phosphate-mannose-protein mannosyltransferase 125 258 1.0E-14 T 28-03-2018 IPR003342 Glycosyl transferase family 39/83 GO:0000030|GO:0006493|GO:0016020 Reactome: R-HSA-5173105 CNX65_RS03150 c3d6e915665c8a859bff252890819f3b 523 Pfam PF16192 C-terminal four TMM region of protein-O-mannosyltransferase 332 522 4.2E-19 T 28-03-2018 IPR032421 Protein O-mannosyl-transferase, C-terminal four TM domain KEGG: 00500+2.4.1.10|KEGG: 00514+2.4.1.109|KEGG: 00515+2.4.1.109|MetaCyc: PWY-822|Reactome: R-HSA-5173105 CNX65_RS03975 d4b9f1629bb490ee4a1a0dfffd683901 106 Gene3D G3DSA:2.30.110.10 11 103 7.8E-6 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS08420 5ac76dd2302a111620fd11d1e7e49991 159 Pfam PF03073 TspO/MBR family 19 156 1.2E-40 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CNX65_RS08420 5ac76dd2302a111620fd11d1e7e49991 159 PIRSF PIRSF005859 5 159 1.4E-42 T 28-03-2018 IPR004307 TspO/MBR-related protein GO:0016021 CNX65_RS34480 8fc463eb4c36fbadbe6b294ea5c713b4 212 Gene3D G3DSA:3.30.1050.10 91 212 7.1E-22 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS34480 8fc463eb4c36fbadbe6b294ea5c713b4 212 SUPERFAMILY SSF55718 107 209 1.04E-19 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS34480 8fc463eb4c36fbadbe6b294ea5c713b4 212 Pfam PF02036 SCP-2 sterol transfer family 119 208 7.0E-14 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS30735 53aa502d3684569c14e4badf43f6ba50 139 Pfam PF00720 Subtilisin inhibitor-like 39 122 7.8E-25 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS30735 53aa502d3684569c14e4badf43f6ba50 139 ProDom PD004028 INHIBITOR PROTEASE SERINE DIRECT SEQUENCING SUBTILISIN PRECURSOR SIGNAL INHIBITOR-LIKE INHIBITOR 56 126 2.0E-10 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS30735 53aa502d3684569c14e4badf43f6ba50 139 SUPERFAMILY SSF55399 38 136 3.66E-21 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS30735 53aa502d3684569c14e4badf43f6ba50 139 Gene3D G3DSA:3.30.350.10 38 136 1.5E-24 T 28-03-2018 IPR023549 Subtilisin inhibitor GO:0004867 CNX65_RS00675 791e574ef9d1fed9bd6d4aadb3797708 303 Pfam PF01061 ABC-2 type transporter 38 264 1.5E-24 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS14895 95f158c77bce6bfdc4e76fa77901d370 374 Gene3D G3DSA:3.20.20.70 1 370 1.1E-101 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS14895 95f158c77bce6bfdc4e76fa77901d370 374 SUPERFAMILY SSF51395 10 364 2.65E-94 T 28-03-2018 CNX65_RS14895 95f158c77bce6bfdc4e76fa77901d370 374 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 15 361 1.8E-62 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CNX65_RS23835 b222fa251f65211d6032d43a6a2c4477 423 Pfam PF04143 Sulphur transport 75 403 3.1E-64 T 28-03-2018 IPR007272 Sulphur transport domain CNX65_RS16955 355cc76774fc3babdc0ace97887f8ec4 176 SUPERFAMILY SSF109854 10 169 4.27E-32 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS16955 355cc76774fc3babdc0ace97887f8ec4 176 Pfam PF04978 Protein of unknown function (DUF664) 15 169 3.3E-21 T 28-03-2018 IPR007061 Protein of unknown function DUF664 CNX65_RS16955 355cc76774fc3babdc0ace97887f8ec4 176 Gene3D G3DSA:1.20.120.450 5 171 2.6E-32 T 28-03-2018 CNX65_RS10505 64e97f00f558bcffa202ed3946441158 303 Gene3D G3DSA:1.10.3720.10 27 303 3.9E-23 T 28-03-2018 CNX65_RS10505 64e97f00f558bcffa202ed3946441158 303 SUPERFAMILY SSF161098 23 298 5.36E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS15370 3ebafaba75a026356c9662c4f6ff75ba 202 SUPERFAMILY SSF46785 7 178 1.8E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS15370 3ebafaba75a026356c9662c4f6ff75ba 202 Pfam PF03551 Transcriptional regulator PadR-like family 11 85 8.4E-11 T 28-03-2018 IPR005149 Transcription regulator PadR, N-terminal CNX65_RS15370 3ebafaba75a026356c9662c4f6ff75ba 202 Gene3D G3DSA:1.10.10.10 2 98 2.0E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS09410 d304b20baadc754cade2970a7f4358dc 368 SUPERFAMILY SSF53300 205 350 3.86E-21 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS09410 d304b20baadc754cade2970a7f4358dc 368 Gene3D G3DSA:3.40.50.410 163 354 2.6E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS09410 d304b20baadc754cade2970a7f4358dc 368 Pfam PF05762 VWA domain containing CoxE-like protein 143 361 5.4E-56 T 28-03-2018 IPR008912 Uncharacterised protein family CoxE-like CNX65_RS09410 d304b20baadc754cade2970a7f4358dc 368 SMART SM00327 205 364 6.1E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS14850 64b3ee68da49bf27551ecc362d83a5f8 191 Pfam PF09684 Phage tail protein (Tail_P2_I) 36 128 1.3E-13 T 28-03-2018 IPR006521 Tail protein I CNX65_RS14850 64b3ee68da49bf27551ecc362d83a5f8 191 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 17 117 7.8E-29 T 28-03-2018 IPR011748 Uncharacterised protein family, phage tail-like CNX65_RS18140 953e3ba57a6a0fb90769c2b1c825cc7e 741 Pfam PF04738 Lantibiotic dehydratase, C terminus 611 690 1.1E-12 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CNX65_RS18140 953e3ba57a6a0fb90769c2b1c825cc7e 741 Pfam PF04738 Lantibiotic dehydratase, C terminus 69 354 3.9E-23 T 28-03-2018 IPR006827 Lantibiotic dehydratase, C-terminal CNX65_RS00155 547f276977925af9e0a3118fb8805f52 211 SUPERFAMILY SSF51735 1 205 8.11E-36 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00155 547f276977925af9e0a3118fb8805f52 211 Pfam PF13460 NAD(P)H-binding 7 190 8.8E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS00155 547f276977925af9e0a3118fb8805f52 211 Gene3D G3DSA:3.40.50.720 1 211 6.4E-30 T 28-03-2018 CNX65_RS29040 5cdcdcf5bf0d4a63f83c21e69a731d0e 107 Pfam PF10611 Protein of unknown function (DUF2469) 1 100 9.9E-53 T 28-03-2018 IPR019592 Protein of unknown function DUF2469 CNX65_RS20830 4eecce046d40ff8ebb1fe4ecb0128c1f 187 Pfam PF07331 Tripartite tricarboxylate transporter TctB family 10 179 2.1E-21 T 28-03-2018 IPR009936 Protein of unknown function DUF1468 CNX65_RS15495 92746986623ab99266eed03f3135d0b7 410 SMART SM00387 322 410 0.0021 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS15495 92746986623ab99266eed03f3135d0b7 410 Gene3D G3DSA:3.30.565.10 293 410 1.1E-16 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS15495 92746986623ab99266eed03f3135d0b7 410 Pfam PF07730 Histidine kinase 225 289 2.1E-10 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS15495 92746986623ab99266eed03f3135d0b7 410 SUPERFAMILY SSF55874 298 408 1.51E-13 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS22495 9c54394cc3214bf86f2c1ce778be7931 133 Pfam PF03724 META domain 46 130 1.1E-21 T 28-03-2018 IPR005184 Domain of unknown function DUF306, Meta/HslJ CNX65_RS21970 bbe4d04e64c43638f0f384bae0cfac5a 316 Gene3D G3DSA:3.40.640.10 12 209 4.7E-37 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS21970 bbe4d04e64c43638f0f384bae0cfac5a 316 SUPERFAMILY SSF53383 2 308 6.45E-67 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS21970 bbe4d04e64c43638f0f384bae0cfac5a 316 Gene3D G3DSA:3.90.1150.10 210 315 4.0E-19 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS21970 bbe4d04e64c43638f0f384bae0cfac5a 316 Pfam PF00155 Aminotransferase class I and II 22 304 1.9E-43 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS04490 d29a4fc8d4e4350838165a29e6897cb5 170 SMART SM00450 27 127 3.6E-12 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS04490 d29a4fc8d4e4350838165a29e6897cb5 170 Pfam PF00581 Rhodanese-like domain 30 123 1.4E-10 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS04490 d29a4fc8d4e4350838165a29e6897cb5 170 SUPERFAMILY SSF52821 23 130 3.93E-22 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS04490 d29a4fc8d4e4350838165a29e6897cb5 170 Gene3D G3DSA:3.40.250.10 27 148 3.1E-20 T 28-03-2018 IPR001763 Rhodanese-like domain CNX65_RS08580 4b59508b8b3b07464a2748b70d83bdfc 397 SUPERFAMILY SSF56112 35 315 3.21E-17 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS08580 4b59508b8b3b07464a2748b70d83bdfc 397 Gene3D G3DSA:3.90.1200.10 123 330 1.7E-6 T 28-03-2018 CNX65_RS08580 4b59508b8b3b07464a2748b70d83bdfc 397 Gene3D G3DSA:3.30.200.20 19 119 6.8E-4 T 28-03-2018 CNX65_RS32545 f25ff37ff6110765530c47b604d6a846 279 Pfam PF02405 Permease MlaE 62 266 1.5E-58 T 28-03-2018 IPR030802 ABC transporter permease MalE GO:0006810|GO:0043190 CNX65_RS04300 45972a46d9e8b609bc58f4e9eaa93e05 492 Pfam PF09660 Protein of unknown function (DUF2397) 10 486 1.2E-120 T 28-03-2018 IPR013493 Conserved hypothetical protein CHP02677 CNX65_RS06805 7a7ff44c120f54c33742b3a50beb4de8 374 PRINTS PR00162 Rieske 2Fe-2S subunit signature 294 305 3.5E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CNX65_RS06805 7a7ff44c120f54c33742b3a50beb4de8 374 PRINTS PR00162 Rieske 2Fe-2S subunit signature 330 342 3.5E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CNX65_RS06805 7a7ff44c120f54c33742b3a50beb4de8 374 PRINTS PR00162 Rieske 2Fe-2S subunit signature 316 328 3.5E-5 T 28-03-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 CNX65_RS06805 7a7ff44c120f54c33742b3a50beb4de8 374 Gene3D G3DSA:2.102.10.10 203 374 9.3E-43 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS06805 7a7ff44c120f54c33742b3a50beb4de8 374 Pfam PF00355 Rieske [2Fe-2S] domain 259 346 1.4E-11 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS06805 7a7ff44c120f54c33742b3a50beb4de8 374 SUPERFAMILY SSF50022 288 372 6.02E-28 T 28-03-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 CNX65_RS28355 84195cefb02f6d1b2280b72853a03a0a 442 SMART SM01230 119 359 1.9E-74 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS28355 84195cefb02f6d1b2280b72853a03a0a 442 Gene3D G3DSA:3.10.20.70 20 115 1.1E-14 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS28355 84195cefb02f6d1b2280b72853a03a0a 442 Pfam PF00120 Glutamine synthetase, catalytic domain 121 427 1.7E-70 T 28-03-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS28355 84195cefb02f6d1b2280b72853a03a0a 442 SUPERFAMILY SSF54368 16 118 5.23E-6 T 28-03-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 CNX65_RS28355 84195cefb02f6d1b2280b72853a03a0a 442 Gene3D G3DSA:3.30.590.10 117 440 8.8E-90 T 28-03-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 CNX65_RS28355 84195cefb02f6d1b2280b72853a03a0a 442 SUPERFAMILY SSF55931 120 432 7.85E-80 T 28-03-2018 CNX65_RS04025 9bc762c0448d6ff42e8c2804f53e1642 362 Pfam PF10094 Uncharacterized protein conserved in bacteria (DUF2332) 4 356 2.2E-100 T 28-03-2018 IPR011200 Uncharacterised conserved protein UCP012608 CNX65_RS22905 946354a34b82653b65ae1fbc021a1070 415 SUPERFAMILY SSF51445 8 326 1.09E-31 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS22905 946354a34b82653b65ae1fbc021a1070 415 Gene3D G3DSA:3.20.20.80 7 339 5.0E-30 T 28-03-2018 CNX65_RS27645 a88787798eee4fd62d43e5400b6fe864 113 Pfam PF09848 Uncharacterized conserved protein (DUF2075) 26 96 1.8E-6 T 28-03-2018 IPR018647 Domain of unknown function DUF2075 CNX65_RS27790 5eda95b3fba8e3a967f67260b3355f5f 838 Pfam PF02687 FtsX-like permease family 739 830 1.0E-11 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS27790 5eda95b3fba8e3a967f67260b3355f5f 838 Pfam PF02687 FtsX-like permease family 286 381 4.2E-14 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS27790 5eda95b3fba8e3a967f67260b3355f5f 838 Pfam PF12704 MacB-like periplasmic core domain 17 225 2.1E-13 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CNX65_RS27790 5eda95b3fba8e3a967f67260b3355f5f 838 Pfam PF12704 MacB-like periplasmic core domain 486 680 1.0E-7 T 28-03-2018 IPR025857 MacB-like periplasmic core domain CNX65_RS29865 a9c232e8bfbd5bd458ec955a882b9061 198 SUPERFAMILY SSF51182 23 167 3.96E-29 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS29865 a9c232e8bfbd5bd458ec955a882b9061 198 Pfam PF05995 Cysteine dioxygenase type I 53 166 1.0E-18 T 28-03-2018 IPR010300 Cysteine dioxygenase type I GO:0005506|GO:0016702|GO:0055114 KEGG: 00270+1.13.11.20|KEGG: 00430+1.13.11.20|MetaCyc: PWY-5331|Reactome: R-HSA-1614558 CNX65_RS29865 a9c232e8bfbd5bd458ec955a882b9061 198 Gene3D G3DSA:2.60.120.10 14 176 2.2E-24 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS31880 176880c8b4b17954cf2a5a7138c9a477 309 Pfam PF04657 Putative inner membrane exporter, YdcZ 10 152 1.5E-27 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CNX65_RS31880 176880c8b4b17954cf2a5a7138c9a477 309 Pfam PF04657 Putative inner membrane exporter, YdcZ 168 301 1.3E-14 T 28-03-2018 IPR006750 Putative inner membrane exporter, YdcZ CNX65_RS09830 a01ef359a8d3808bd6e6682760e3a195 285 SUPERFAMILY SSF53474 32 273 3.08E-42 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS09830 a01ef359a8d3808bd6e6682760e3a195 285 Gene3D G3DSA:3.40.50.1820 28 285 3.1E-41 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS22465 0189b1125cda06fce45031def2e2e4bf 127 ProSitePatterns PS00561 CBM2a (carbohydrate-binding type-2) domain signature. 97 110 - T 28-03-2018 IPR018366 Carbohydrate-binding type-2, conserved site GO:0004553|GO:0005975|GO:0030246 CNX65_RS22465 0189b1125cda06fce45031def2e2e4bf 127 Gene3D G3DSA:2.60.40.290 73 127 2.3E-4 T 28-03-2018 CNX65_RS09710 4d36639d59a4668d2f003fa5f752f12d 279 SMART SM00530 13 68 7.6E-11 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS09710 4d36639d59a4668d2f003fa5f752f12d 279 Gene3D G3DSA:1.10.3100.10 5 174 9.9E-18 T 28-03-2018 IPR027910 YdiL-like domain CNX65_RS09710 4d36639d59a4668d2f003fa5f752f12d 279 SUPERFAMILY SSF47413 9 74 4.02E-12 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS09710 4d36639d59a4668d2f003fa5f752f12d 279 Pfam PF13560 Helix-turn-helix domain 9 71 8.1E-13 T 28-03-2018 CNX65_RS34905 08d59d34d18110d45a11a59c3688e759 295 Pfam PF03466 LysR substrate binding domain 89 288 3.1E-33 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS34905 08d59d34d18110d45a11a59c3688e759 295 SUPERFAMILY SSF46785 2 111 1.34E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34905 08d59d34d18110d45a11a59c3688e759 295 Gene3D G3DSA:3.40.190.10 89 179 4.5E-21 T 28-03-2018 CNX65_RS34905 08d59d34d18110d45a11a59c3688e759 295 Gene3D G3DSA:3.40.190.10 180 271 1.6E-22 T 28-03-2018 CNX65_RS34905 08d59d34d18110d45a11a59c3688e759 295 Gene3D G3DSA:1.10.10.10 1 84 1.7E-22 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS34905 08d59d34d18110d45a11a59c3688e759 295 SUPERFAMILY SSF53850 92 292 2.9E-32 T 28-03-2018 CNX65_RS34905 08d59d34d18110d45a11a59c3688e759 295 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 5 63 5.2E-20 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS00025 3bf6ee8e302cd8143d0bab41987ef583 143 Pfam PF05258 Protein of unknown function (DUF721) 31 118 2.2E-25 T 28-03-2018 IPR007922 Protein of unknown function DUF721/UPF0232 CNX65_RS01980 3fb25af7f135cac01d848802944a5b28 258 Gene3D G3DSA:3.40.50.1110 4 196 5.8E-30 T 28-03-2018 CNX65_RS01980 3fb25af7f135cac01d848802944a5b28 258 SUPERFAMILY SSF52266 5 190 1.3E-35 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS01980 3fb25af7f135cac01d848802944a5b28 258 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 9 181 8.8E-25 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS08460 ec68cc2b8ad492d49bed6e68b9392d15 627 SUPERFAMILY SSF82866 392 591 1.44E-29 T 28-03-2018 CNX65_RS08460 ec68cc2b8ad492d49bed6e68b9392d15 627 Gene3D G3DSA:1.20.1640.10 365 592 1.6E-26 T 28-03-2018 CNX65_RS08460 ec68cc2b8ad492d49bed6e68b9392d15 627 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 40 586 6.2E-118 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CNX65_RS08460 ec68cc2b8ad492d49bed6e68b9392d15 627 Pfam PF02355 Protein export membrane protein 414 590 6.2E-11 T 28-03-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial CNX65_RS08460 ec68cc2b8ad492d49bed6e68b9392d15 627 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 345 578 1.6E-67 T 28-03-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial CNX65_RS08460 ec68cc2b8ad492d49bed6e68b9392d15 627 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 11 601 39.185 T 28-03-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 CNX65_RS20595 3a22a3aa19c453d0f8a35b860c268c6d 232 Gene3D G3DSA:3.40.30.10 14 192 3.3E-15 T 28-03-2018 CNX65_RS20595 3a22a3aa19c453d0f8a35b860c268c6d 232 SUPERFAMILY SSF52833 50 192 2.94E-5 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS20595 3a22a3aa19c453d0f8a35b860c268c6d 232 Pfam PF05988 Bacterial protein of unknown function (DUF899) 1 212 1.0E-85 T 28-03-2018 IPR010296 Protein of unknown function DUF899, thioredoxin-like CNX65_RS08125 3478e70748c1798b913572966acfcf9d 375 Pfam PF07730 Histidine kinase 190 253 2.0E-9 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS08125 3478e70748c1798b913572966acfcf9d 375 Gene3D G3DSA:3.30.565.10 255 370 4.4E-11 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16865 9d5874a923074197388107396f73aa79 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16865 9d5874a923074197388107396f73aa79 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 2.0E-8 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16865 9d5874a923074197388107396f73aa79 193 Gene3D G3DSA:1.10.10.60 46 178 3.5E-8 T 28-03-2018 CNX65_RS16865 9d5874a923074197388107396f73aa79 193 Gene3D G3DSA:1.10.10.60 5 45 4.9E-15 T 28-03-2018 CNX65_RS16865 9d5874a923074197388107396f73aa79 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 57 1.8E-13 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS16865 9d5874a923074197388107396f73aa79 193 SUPERFAMILY SSF46689 5 81 6.16E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS00275 7faba85f08a595e5fc746cee4a5ea67f 428 Pfam PF16822 SGNH hydrolase-like domain, acetyltransferase AlgX 143 365 2.1E-19 T 28-03-2018 IPR031811 AlgX/AlgJ, SGNH hydrolase-like domain CNX65_RS00275 7faba85f08a595e5fc746cee4a5ea67f 428 Gene3D G3DSA:3.40.50.1110 73 291 0.0024 T 28-03-2018 CNX65_RS11780 4df42e7f8588d056a6b5fe163597299f 158 Gene3D G3DSA:3.40.1550.10 5 145 2.0E-4 T 28-03-2018 IPR028976 CheC-like domain CNX65_RS34365 fc8e520dd27c1723bb70a95398d7ca48 397 Gene3D G3DSA:2.60.40.10 200 335 2.4E-10 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS34365 fc8e520dd27c1723bb70a95398d7ca48 397 SUPERFAMILY SSF117074 19 84 2.09E-10 T 28-03-2018 CNX65_RS34365 fc8e520dd27c1723bb70a95398d7ca48 397 Gene3D G3DSA:2.60.40.10 23 115 4.4E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS26215 64709ada820f765b20ff5de2f1122cd3 135 Pfam PF06103 Bacterial protein of unknown function (DUF948) 6 87 5.7E-19 T 28-03-2018 IPR009293 Uncharacterised protein family UPF0478 CNX65_RS34620 358ad57ba78eb612ecd9fdd031bc62af 511 SUPERFAMILY SSF52540 43 226 2.15E-22 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS34620 358ad57ba78eb612ecd9fdd031bc62af 511 Pfam PF00350 Dynamin family 47 154 1.3E-10 T 28-03-2018 IPR022812 Dynamin superfamily CNX65_RS34620 358ad57ba78eb612ecd9fdd031bc62af 511 Gene3D G3DSA:3.40.50.300 46 304 3.0E-27 T 28-03-2018 CNX65_RS23615 475af1347addbd1347e86c3486c3a7f3 241 Pfam PF14256 YwiC-like protein 13 137 1.3E-40 T 28-03-2018 IPR025576 YwiC-like protein CNX65_RS03025 f81833cbc2acdca0d3bc38280878a9d7 116 TIGRFAM TIGR02118 TIGR02118: conserved hypothetical protein 1 86 8.6E-16 T 28-03-2018 IPR009799 EthD domain CNX65_RS03025 f81833cbc2acdca0d3bc38280878a9d7 116 Pfam PF07110 EthD domain 14 82 4.6E-7 T 28-03-2018 IPR009799 EthD domain CNX65_RS03025 f81833cbc2acdca0d3bc38280878a9d7 116 SUPERFAMILY SSF54909 1 85 3.22E-18 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS03025 f81833cbc2acdca0d3bc38280878a9d7 116 Gene3D G3DSA:3.30.70.100 1 102 9.1E-18 T 28-03-2018 CNX65_RS01970 ecd04e087344a82bd9ba671702a8ad25 345 SUPERFAMILY SSF101478 8 330 1.44E-42 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS01970 ecd04e087344a82bd9ba671702a8ad25 345 Pfam PF03747 ADP-ribosylglycohydrolase 14 311 7.3E-50 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS01970 ecd04e087344a82bd9ba671702a8ad25 345 Gene3D G3DSA:1.10.4080.10 4 336 3.7E-55 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS27745 215cb346e0744e7e5d03c65464053994 374 SUPERFAMILY SSF89796 4 373 3.79E-120 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS27745 215cb346e0744e7e5d03c65464053994 374 Gene3D G3DSA:3.40.50.10540 1 374 1.3E-121 T 28-03-2018 IPR023606 CoA-transferase family III domain CNX65_RS27745 215cb346e0744e7e5d03c65464053994 374 Pfam PF02515 CoA-transferase family III 6 350 3.6E-82 T 28-03-2018 IPR003673 CoA-transferase family III GO:0003824 CNX65_RS11615 c397627d1a27636b3a0b87849660d450 185 Pfam PF14124 Domain of unknown function (DUF4291) 6 172 4.9E-59 T 28-03-2018 IPR025633 Protein of unknown function DUF4291 CNX65_RS06275 6729871bc88817bbd41f751c38c9c5f9 334 Pfam PF03773 Predicted permease 53 329 1.5E-51 T 28-03-2018 IPR005524 Predicted permease DUF318 CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 Pfam PF00106 short chain dehydrogenase 4 182 3.6E-31 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 Gene3D G3DSA:3.40.50.720 1 220 8.6E-43 T 28-03-2018 CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 SUPERFAMILY SSF51735 3 238 1.31E-46 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 115 131 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 70 81 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 141 160 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 164 181 2.5E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 128 156 - T 28-03-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 121 129 1.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 70 81 1.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12840 ff0c765123eea6248b2030c57e431be0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 141 160 1.2E-5 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS23300 0cda99727d9f16459b0b38c0243c53a2 334 Gene3D G3DSA:2.60.120.260 9 143 1.9E-11 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS23300 0cda99727d9f16459b0b38c0243c53a2 334 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 152 321 1.3E-21 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS23300 0cda99727d9f16459b0b38c0243c53a2 334 Gene3D G3DSA:3.40.50.1110 144 334 8.0E-28 T 28-03-2018 CNX65_RS23300 0cda99727d9f16459b0b38c0243c53a2 334 SUPERFAMILY SSF52266 146 331 1.97E-29 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS19825 4182a4aef46f80a67e0f5137a3dcbae2 314 Pfam PF13560 Helix-turn-helix domain 10 90 6.1E-18 T 28-03-2018 CNX65_RS19825 4182a4aef46f80a67e0f5137a3dcbae2 314 SMART SM00530 14 87 1.7E-8 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS19825 4182a4aef46f80a67e0f5137a3dcbae2 314 Gene3D G3DSA:1.10.260.40 7 96 6.2E-18 T 28-03-2018 CNX65_RS19825 4182a4aef46f80a67e0f5137a3dcbae2 314 SUPERFAMILY SSF47413 35 88 4.44E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS06790 e43768134a30e65d736c3e580efb2dbe 136 Gene3D G3DSA:3.30.70.970 31 126 1.2E-5 T 28-03-2018 IPR009671 Regulator of ribonuclease activity B domain CNX65_RS16220 26f4db1553e951dd050b27eed3850d15 220 Gene3D G3DSA:3.40.50.150 4 219 7.1E-44 T 28-03-2018 CNX65_RS16220 26f4db1553e951dd050b27eed3850d15 220 Pfam PF01596 O-methyltransferase 22 218 7.2E-55 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CNX65_RS16220 26f4db1553e951dd050b27eed3850d15 220 SUPERFAMILY SSF53335 8 218 4.03E-49 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS24275 a24dc14f318dd3ec748322bce7c46ae2 291 SUPERFAMILY SSF52266 33 284 5.33E-62 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS24275 a24dc14f318dd3ec748322bce7c46ae2 291 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 38 273 2.7E-29 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS24275 a24dc14f318dd3ec748322bce7c46ae2 291 Gene3D G3DSA:3.40.50.1110 29 290 2.2E-37 T 28-03-2018 CNX65_RS29840 ff59e9139c92d7ba22fb4d943a227650 383 Gene3D G3DSA:3.40.50.150 83 244 3.3E-8 T 28-03-2018 CNX65_RS02920 a631b4ab710efbcd176e48ecf2c864f9 157 SUPERFAMILY SSF55811 10 148 2.17E-34 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS02920 a631b4ab710efbcd176e48ecf2c864f9 157 ProSitePatterns PS00893 Nudix box signature. 49 70 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS02920 a631b4ab710efbcd176e48ecf2c864f9 157 Pfam PF00293 NUDIX domain 20 134 1.2E-18 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS02920 a631b4ab710efbcd176e48ecf2c864f9 157 Gene3D G3DSA:3.90.79.10 9 155 5.9E-29 T 28-03-2018 CNX65_RS00660 fe2d2939a3692697a6df3fa4cd5c025f 265 Pfam PF17210 SdrD B-like domain 32 106 2.0E-8 T 28-03-2018 IPR033764 SD-repeat containing protein, B domain CNX65_RS00660 fe2d2939a3692697a6df3fa4cd5c025f 265 SUPERFAMILY SSF117074 27 98 2.48E-9 T 28-03-2018 CNX65_RS00660 fe2d2939a3692697a6df3fa4cd5c025f 265 Gene3D G3DSA:2.60.40.10 28 265 1.4E-11 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS23870 27060013d40b3b8f3175a970e6be7a85 984 SUPERFAMILY SSF48208 92 461 2.58E-34 T 28-03-2018 IPR008928 Six-hairpin glycosidase-like GO:0003824 CNX65_RS23870 27060013d40b3b8f3175a970e6be7a85 984 Pfam PF00754 F5/8 type C domain 556 680 1.9E-10 T 28-03-2018 IPR000421 Coagulation factor 5/8 C-terminal domain CNX65_RS23870 27060013d40b3b8f3175a970e6be7a85 984 Gene3D G3DSA:1.50.10.10 78 451 1.2E-28 T 28-03-2018 CNX65_RS23870 27060013d40b3b8f3175a970e6be7a85 984 Gene3D G3DSA:2.60.120.260 549 694 8.8E-22 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS23870 27060013d40b3b8f3175a970e6be7a85 984 SUPERFAMILY SSF49785 555 677 3.33E-9 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS23870 27060013d40b3b8f3175a970e6be7a85 984 Gene3D G3DSA:2.60.420.10 452 543 2.2E-9 T 28-03-2018 CNX65_RS03200 46e1cfe0b7bfc3a2ab6eece8a25824f1 273 Gene3D G3DSA:3.40.190.10 36 133 5.5E-21 T 28-03-2018 CNX65_RS03200 46e1cfe0b7bfc3a2ab6eece8a25824f1 273 Pfam PF03180 NLPA lipoprotein 37 273 1.7E-89 T 28-03-2018 IPR004872 Lipoprotein NlpA family CNX65_RS03200 46e1cfe0b7bfc3a2ab6eece8a25824f1 273 Gene3D G3DSA:3.40.190.10 134 273 4.1E-51 T 28-03-2018 CNX65_RS03200 46e1cfe0b7bfc3a2ab6eece8a25824f1 273 SUPERFAMILY SSF53850 37 273 1.33E-78 T 28-03-2018 CNX65_RS03200 46e1cfe0b7bfc3a2ab6eece8a25824f1 273 PIRSF PIRSF002854 1 273 5.3E-103 T 28-03-2018 IPR004872 Lipoprotein NlpA family CNX65_RS28420 fe1a53717a6f86c5033ccff26d01fbe7 194 Pfam PF01066 CDP-alcohol phosphatidyltransferase 11 81 3.9E-14 T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS28420 fe1a53717a6f86c5033ccff26d01fbe7 194 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 28-03-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 CNX65_RS28420 fe1a53717a6f86c5033ccff26d01fbe7 194 PIRSF PIRSF000847 8 191 2.1E-46 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CNX65_RS28420 fe1a53717a6f86c5033ccff26d01fbe7 194 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 11 180 1.3E-39 T 28-03-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 CNX65_RS30240 464725f8a4578c68d8482b1ca565867c 389 Pfam PF00953 Glycosyl transferase family 4 95 261 1.2E-31 T 28-03-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193 CNX65_RS19025 27936bafc20b700a24eeebd2a379e5b6 141 SUPERFAMILY SSF46785 3 129 2.39E-26 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS19025 27936bafc20b700a24eeebd2a379e5b6 141 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 1 127 4.0E-26 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CNX65_RS19025 27936bafc20b700a24eeebd2a379e5b6 141 Pfam PF02082 Transcriptional regulator 1 80 2.0E-18 T 28-03-2018 IPR000944 Transcription regulator Rrf2-type CNX65_RS19025 27936bafc20b700a24eeebd2a379e5b6 141 Gene3D G3DSA:1.10.10.10 1 131 3.2E-27 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS03455 4ccdf13d13ad76e62f592046d0f1d2bc 401 Gene3D G3DSA:3.20.20.370 76 391 7.3E-28 T 28-03-2018 CNX65_RS03455 4ccdf13d13ad76e62f592046d0f1d2bc 401 SUPERFAMILY SSF88713 74 129 5.56E-20 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS03455 4ccdf13d13ad76e62f592046d0f1d2bc 401 SUPERFAMILY SSF88713 161 383 5.56E-20 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS13495 6c2659704620852dd908581bfa321015 273 SUPERFAMILY SSF55909 4 266 1.32E-51 T 28-03-2018 CNX65_RS13495 6c2659704620852dd908581bfa321015 273 Pfam PF02274 Amidinotransferase 62 265 3.2E-14 T 28-03-2018 CNX65_RS13495 6c2659704620852dd908581bfa321015 273 Gene3D G3DSA:3.75.10.10 2 267 1.0E-59 T 28-03-2018 CNX65_RS14675 3e7ba45dd326b86914e6edd7dfdf8853 658 SMART SM00331 360 576 1.9E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS14675 3e7ba45dd326b86914e6edd7dfdf8853 658 SUPERFAMILY SSF55781 202 343 6.98E-7 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14675 3e7ba45dd326b86914e6edd7dfdf8853 658 Gene3D G3DSA:3.60.40.10 341 578 9.2E-29 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS14675 3e7ba45dd326b86914e6edd7dfdf8853 658 SUPERFAMILY SSF81606 377 575 9.15E-8 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS14675 3e7ba45dd326b86914e6edd7dfdf8853 658 Gene3D G3DSA:3.30.450.40 165 340 6.0E-18 T 28-03-2018 IPR029016 GAF domain-like CNX65_RS14675 3e7ba45dd326b86914e6edd7dfdf8853 658 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 390 576 1.6E-37 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS09630 82130eedef7c81dbf260c81b7473eee4 298 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 102 288 1.3E-9 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09630 82130eedef7c81dbf260c81b7473eee4 298 Gene3D G3DSA:1.10.3720.10 17 298 4.5E-40 T 28-03-2018 CNX65_RS09630 82130eedef7c81dbf260c81b7473eee4 298 SUPERFAMILY SSF161098 59 285 2.4E-44 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS09310 54ff653d74b69fcf0831e98742bad05e 373 SUPERFAMILY SSF53822 38 359 6.28E-67 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS09310 54ff653d74b69fcf0831e98742bad05e 373 Gene3D G3DSA:3.40.50.2300 210 347 8.6E-16 T 28-03-2018 CNX65_RS09310 54ff653d74b69fcf0831e98742bad05e 373 Gene3D G3DSA:3.40.50.2300 39 203 2.6E-30 T 28-03-2018 CNX65_RS09310 54ff653d74b69fcf0831e98742bad05e 373 Pfam PF13407 Periplasmic binding protein domain 41 326 6.4E-65 T 28-03-2018 IPR025997 Periplasmic binding protein CNX65_RS17555 cd30211bbec0215d9d0ed7978c659edd 216 SUPERFAMILY SSF56784 10 203 1.59E-28 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS17555 cd30211bbec0215d9d0ed7978c659edd 216 Gene3D G3DSA:3.40.50.1000 2 209 2.7E-23 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS17555 cd30211bbec0215d9d0ed7978c659edd 216 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 101 193 6.9E-16 T 28-03-2018 IPR006439 HAD hydrolase, subfamily IA GO:0008152|GO:0016787 CNX65_RS17555 cd30211bbec0215d9d0ed7978c659edd 216 Pfam PF00702 haloacid dehalogenase-like hydrolase 102 192 6.2E-7 T 28-03-2018 CNX65_RS27840 ff1d86be11babae58437efd861128105 861 Gene3D G3DSA:3.30.870.10 16 164 1.5E-4 T 28-03-2018 CNX65_RS27840 ff1d86be11babae58437efd861128105 861 Gene3D G3DSA:3.40.470.10 393 523 0.013 T 28-03-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 CNX65_RS34910 54c1435d0ee9a1eab7b73486d531445f 175 Pfam PF14136 Domain of unknown function (DUF4303) 32 98 1.8E-10 T 28-03-2018 IPR025409 Protein of unknown function DUF4303 CNX65_RS34910 54c1435d0ee9a1eab7b73486d531445f 175 Pfam PF14136 Domain of unknown function (DUF4303) 110 159 5.3E-8 T 28-03-2018 IPR025409 Protein of unknown function DUF4303 CNX65_RS13020 d918669f34cd38b0a748abcdbd45595a 220 Pfam PF08348 YheO-like PAS domain 13 121 8.0E-32 T 28-03-2018 IPR013559 YheO-like CNX65_RS13020 d918669f34cd38b0a748abcdbd45595a 220 Gene3D G3DSA:1.10.10.60 158 217 0.0024 T 28-03-2018 CNX65_RS13020 d918669f34cd38b0a748abcdbd45595a 220 Pfam PF13309 HTH domain 145 205 9.6E-15 T 28-03-2018 CNX65_RS13020 d918669f34cd38b0a748abcdbd45595a 220 ProDom PD037769 DNA-BINDING YHEO UNCHARACTERIZED BACTERIA SIMILAR HI0575 CONTAINING TRANSCRIPTION REGULATOR HELIX-TURN-HELIX 19 125 2.0E-34 T 28-03-2018 IPR013559 YheO-like CNX65_RS09600 7257626a4b386f9a70775a84a10961bf 685 Pfam PF01757 Acyltransferase family 23 348 1.4E-27 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS17325 3f60f6d6f86ac72a3b04bfc0a9c637ae 105 SUPERFAMILY SSF143120 9 79 1.44E-14 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS17325 3f60f6d6f86ac72a3b04bfc0a9c637ae 105 Gene3D G3DSA:3.40.1620.10 6 56 9.5E-14 T 28-03-2018 CNX65_RS17325 3f60f6d6f86ac72a3b04bfc0a9c637ae 105 TIGRFAM TIGR01552 phd_fam: prevent-host-death family protein 9 60 7.3E-14 T 28-03-2018 CNX65_RS17325 3f60f6d6f86ac72a3b04bfc0a9c637ae 105 Pfam PF02604 Antitoxin Phd_YefM, type II toxin-antitoxin system 10 78 3.8E-15 T 28-03-2018 IPR006442 Type II toxin-antitoxin system, antitoxin Phd/YefM CNX65_RS14020 e9916dd3c9a39d5fdca05203e05dcca6 243 Gene3D G3DSA:3.40.30.10 58 243 1.6E-35 T 28-03-2018 CNX65_RS14020 e9916dd3c9a39d5fdca05203e05dcca6 243 Pfam PF13462 Thioredoxin 71 221 1.4E-23 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS14020 e9916dd3c9a39d5fdca05203e05dcca6 243 SUPERFAMILY SSF52833 69 220 2.15E-32 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS10210 569a89495f8d8a654b676a58cb7d7762 179 Gene3D G3DSA:3.40.1410.10 6 165 9.0E-32 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS10210 569a89495f8d8a654b676a58cb7d7762 179 Pfam PF07702 UTRA domain 29 158 1.5E-22 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS10210 569a89495f8d8a654b676a58cb7d7762 179 SUPERFAMILY SSF64288 20 167 9.14E-29 T 28-03-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain CNX65_RS10210 569a89495f8d8a654b676a58cb7d7762 179 SMART SM00866 21 162 1.6E-17 T 28-03-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 CNX65_RS25765 1ec7f485e08cabcaaf46c76bdfc637f3 335 Gene3D G3DSA:1.10.10.10 12 107 0.0045 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26115 a610392990b03c632eef297e5c038cd8 162 SMART SM00530 11 68 3.3E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS26115 a610392990b03c632eef297e5c038cd8 162 Gene3D G3DSA:1.10.260.40 1 70 2.3E-12 T 28-03-2018 CNX65_RS26115 a610392990b03c632eef297e5c038cd8 162 Pfam PF01381 Helix-turn-helix 12 68 7.4E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS26115 a610392990b03c632eef297e5c038cd8 162 SUPERFAMILY SSF47413 4 71 2.03E-9 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS34090 25a46103d509740a744b514a5cb40c3c 176 Pfam PF14011 EspG family 9 157 3.0E-15 T 28-03-2018 IPR025734 EspG family CNX65_RS20690 1f6337152a6106fa77c0b61d93987e5f 597 SUPERFAMILY SSF51905 442 518 3.6E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20690 1f6337152a6106fa77c0b61d93987e5f 597 SUPERFAMILY SSF51905 137 321 3.6E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20690 1f6337152a6106fa77c0b61d93987e5f 597 Gene3D G3DSA:3.50.50.60 140 505 8.0E-26 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS20690 1f6337152a6106fa77c0b61d93987e5f 597 Pfam PF01494 FAD binding domain 141 476 6.2E-10 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS08390 e4daafd30c48b9f5c58fa1046825219a 334 SUPERFAMILY SSF52540 5 256 6.21E-61 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08390 e4daafd30c48b9f5c58fa1046825219a 334 Gene3D G3DSA:3.40.50.300 2 327 1.8E-71 T 28-03-2018 CNX65_RS08390 e4daafd30c48b9f5c58fa1046825219a 334 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS08390 e4daafd30c48b9f5c58fa1046825219a 334 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 238 302 1.3E-18 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS08390 e4daafd30c48b9f5c58fa1046825219a 334 Pfam PF00005 ABC transporter 26 186 1.2E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS08390 e4daafd30c48b9f5c58fa1046825219a 334 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 236 310 4.4E-22 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS08390 e4daafd30c48b9f5c58fa1046825219a 334 SMART SM00382 34 236 3.7E-17 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS13805 742e88b155ad3a9a24d6a8011aace572 305 Pfam PF08021 Siderophore-interacting FAD-binding domain 45 155 1.1E-27 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CNX65_RS13805 742e88b155ad3a9a24d6a8011aace572 305 Gene3D G3DSA:2.40.30.10 35 155 8.6E-30 T 28-03-2018 CNX65_RS13805 742e88b155ad3a9a24d6a8011aace572 305 SUPERFAMILY SSF63380 37 159 5.91E-13 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS13805 742e88b155ad3a9a24d6a8011aace572 305 Pfam PF04954 Siderophore-interacting protein 164 283 9.6E-38 T 28-03-2018 IPR007037 Siderophore-interacting protein CNX65_RS13805 742e88b155ad3a9a24d6a8011aace572 305 Gene3D G3DSA:3.40.50.80 157 304 1.0E-43 T 28-03-2018 CNX65_RS26795 1542a69f3161f8c9631e03ad0af26c4d 644 Pfam PF04865 Baseplate J-like protein 398 567 6.8E-11 T 28-03-2018 IPR006949 Baseplate protein J-like CNX65_RS26795 1542a69f3161f8c9631e03ad0af26c4d 644 TIGRFAM TIGR02243 TIGR02243: putative baseplate assembly protein 7 609 1.5E-150 T 28-03-2018 IPR011749 Conserved hypothetical protein CHP02243 CNX65_RS24655 c3f91c1e0e7d864929f01ed2f86bfed4 466 PIRSF PIRSF006060 1 447 9.5E-49 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS24655 c3f91c1e0e7d864929f01ed2f86bfed4 466 Pfam PF13520 Amino acid permease 10 412 4.9E-24 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS02035 06cf0e79a5a8c161f597c20a870a815e 305 Gene3D G3DSA:3.20.20.100 2 305 4.7E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS02035 06cf0e79a5a8c161f597c20a870a815e 305 SUPERFAMILY SSF51430 4 304 5.89E-64 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS02035 06cf0e79a5a8c161f597c20a870a815e 305 Pfam PF00248 Aldo/keto reductase family 6 295 1.4E-54 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS29395 334da46ccd82bf6025f553ccfa725766 172 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 45 0.0016 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS29395 334da46ccd82bf6025f553ccfa725766 172 SUPERFAMILY SSF51161 3 148 1.94E-39 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS29395 334da46ccd82bf6025f553ccfa725766 172 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 71 103 5.5E-7 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS29395 334da46ccd82bf6025f553ccfa725766 172 Gene3D G3DSA:2.160.10.10 1 170 3.1E-39 T 28-03-2018 CNX65_RS15665 9919bd19c9cdc8bc231e693c13f3e99c 140 SUPERFAMILY SSF55298 12 137 7.07E-28 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS15665 9919bd19c9cdc8bc231e693c13f3e99c 140 Gene3D G3DSA:3.30.1330.40 15 137 5.8E-29 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS15665 9919bd19c9cdc8bc231e693c13f3e99c 140 Pfam PF01042 Endoribonuclease L-PSP 17 137 1.5E-20 T 28-03-2018 IPR006175 YjgF/YER057c/UK114 family CNX65_RS18040 1689cd3a14035787a2bc8be1216b8227 327 Pfam PF01758 Sodium Bile acid symporter family 46 219 6.4E-17 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 Pfam PF01312 FlhB HrpN YscU SpaS Family 8 342 2.0E-108 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 205 223 3.1E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 225 242 3.1E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 9 31 3.1E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 269 284 3.1E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 298 319 3.1E-34 T 28-03-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 Gene3D G3DSA:3.40.1690.10 215 349 1.7E-55 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CNX65_RS11855 7d606f0b9113328695c64c81f9aca018 363 SUPERFAMILY SSF160544 241 347 5.49E-38 T 28-03-2018 IPR029025 Type III secretion system substrate exporter, C-terminal CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 Gene3D G3DSA:3.40.50.720 1 193 5.4E-53 T 28-03-2018 CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.6E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 2.6E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 2.6E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.6E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.6E-28 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 Pfam PF00106 short chain dehydrogenase 6 193 5.9E-47 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 7.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 7.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 7.0E-7 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS07980 577bfcaa376e56c62fc3f241905ac76e 270 SUPERFAMILY SSF51735 2 220 6.0E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS15835 b76991d37674e7d117bf9f1167a37fa9 324 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 107 185 5.2E-23 T 28-03-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS15835 b76991d37674e7d117bf9f1167a37fa9 324 SUPERFAMILY SSF53901 20 322 3.4E-57 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15835 b76991d37674e7d117bf9f1167a37fa9 324 Gene3D G3DSA:3.40.47.10 2 162 1.8E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15835 b76991d37674e7d117bf9f1167a37fa9 324 Gene3D G3DSA:3.40.47.10 163 322 6.2E-33 T 28-03-2018 IPR016039 Thiolase-like GO:0003824|GO:0008152 CNX65_RS15835 b76991d37674e7d117bf9f1167a37fa9 324 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 232 322 2.4E-25 T 28-03-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 CNX65_RS30870 349a286b81096d5cf42a097579deeac5 218 Gene3D G3DSA:1.10.3720.10 2 216 5.6E-24 T 28-03-2018 CNX65_RS30870 349a286b81096d5cf42a097579deeac5 218 SUPERFAMILY SSF161098 16 202 5.36E-28 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS30870 349a286b81096d5cf42a097579deeac5 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 207 2.7E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 PIRSF PIRSF036922 1 394 1.2E-175 T 28-03-2018 IPR014636 RNase H, phosphoglycerate mutase domain-containing CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 Pfam PF13456 Reverse transcriptase-like 7 129 5.3E-27 T 28-03-2018 CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 SUPERFAMILY SSF53254 193 394 6.28E-54 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 Gene3D G3DSA:3.30.420.10 2 148 3.8E-31 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 Gene3D G3DSA:3.40.50.1240 189 394 5.0E-52 T 28-03-2018 IPR029033 Histidine phosphatase superfamily CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 SMART SM00855 195 349 2.3E-18 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 196 388 9.1E-59 T 28-03-2018 IPR013078 Histidine phosphatase superfamily, clade-1 CNX65_RS04345 bcb1ecaaf380838b967618a828aa55fa 394 SUPERFAMILY SSF53098 3 127 4.3E-32 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS11140 89a2d2e991a054b806892c19df7909ff 207 Pfam PF14317 YcxB-like protein 138 199 1.7E-6 T 28-03-2018 IPR025588 YcxB-like protein CNX65_RS33410 a46fc9dd7d2d744f70a046ec030b8441 670 Gene3D G3DSA:3.40.50.300 113 281 4.2E-8 T 28-03-2018 CNX65_RS33410 a46fc9dd7d2d744f70a046ec030b8441 670 SUPERFAMILY SSF52540 115 246 3.98E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01645 0fffcaf271ae742a010c45350bc9cf1a 358 Gene3D G3DSA:1.10.645.10 199 353 6.0E-28 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS01645 0fffcaf271ae742a010c45350bc9cf1a 358 Gene3D G3DSA:1.10.645.10 15 183 4.6E-39 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS01645 0fffcaf271ae742a010c45350bc9cf1a 358 ProSitePatterns PS00535 Respiratory chain NADH dehydrogenase 49 Kd subunit signature. 55 66 - T 28-03-2018 IPR014029 NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS01645 0fffcaf271ae742a010c45350bc9cf1a 358 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 132 279 5.9E-27 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS01645 0fffcaf271ae742a010c45350bc9cf1a 358 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 283 358 6.1E-19 T 28-03-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS01645 0fffcaf271ae742a010c45350bc9cf1a 358 SUPERFAMILY SSF56762 27 358 4.97E-84 T 28-03-2018 IPR029014 NiFe hydrogenase-like Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS11955 18755e4d31c70501b65e8e7d64e28c52 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 35 51 7.6E-5 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CNX65_RS11955 18755e4d31c70501b65e8e7d64e28c52 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 90 103 7.6E-5 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CNX65_RS11955 18755e4d31c70501b65e8e7d64e28c52 105 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 69 85 7.6E-5 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CNX65_RS11955 18755e4d31c70501b65e8e7d64e28c52 105 Pfam PF02049 Flagellar hook-basal body complex protein FliE 26 104 3.2E-19 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CNX65_RS11955 18755e4d31c70501b65e8e7d64e28c52 105 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 105 13.244 T 28-03-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 CNX65_RS06030 7ea06dad5cc246cf97b8147d2e8b1085 89 Gene3D G3DSA:1.10.1220.10 4 44 4.8E-15 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CNX65_RS06030 7ea06dad5cc246cf97b8147d2e8b1085 89 SUPERFAMILY SSF47598 5 50 4.17E-9 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CNX65_RS02710 4a156ac61060269de8393454cad8b724 86 Gene3D G3DSA:1.10.260.40 2 77 1.2E-16 T 28-03-2018 CNX65_RS02710 4a156ac61060269de8393454cad8b724 86 SMART SM00530 15 70 8.2E-13 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS02710 4a156ac61060269de8393454cad8b724 86 SUPERFAMILY SSF47413 11 74 1.32E-16 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS02710 4a156ac61060269de8393454cad8b724 86 Pfam PF01381 Helix-turn-helix 19 68 1.6E-12 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS29495 0e66e6bd4dc5cd6018cc479827112dc7 233 SMART SM00563 40 158 2.7E-36 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS29495 0e66e6bd4dc5cd6018cc479827112dc7 233 Pfam PF01553 Acyltransferase 34 154 2.5E-24 T 28-03-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0008152|GO:0016746 CNX65_RS29495 0e66e6bd4dc5cd6018cc479827112dc7 233 SUPERFAMILY SSF69593 32 222 4.71E-42 T 28-03-2018 CNX65_RS29495 0e66e6bd4dc5cd6018cc479827112dc7 233 Gene3D G3DSA:3.40.1130.10 27 232 1.3E-42 T 28-03-2018 CNX65_RS24015 9b42a0c3612b3aac500ad316a5342e6d 244 Pfam PF00535 Glycosyl transferase family 2 10 137 3.2E-27 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS24015 9b42a0c3612b3aac500ad316a5342e6d 244 Gene3D G3DSA:3.90.550.10 2 239 1.7E-41 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS24015 9b42a0c3612b3aac500ad316a5342e6d 244 SUPERFAMILY SSF53448 5 224 6.83E-44 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS15475 53f24f8a9ac86efd991b201350051c0c 435 Gene3D G3DSA:2.30.40.10 2 74 3.4E-18 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS15475 53f24f8a9ac86efd991b201350051c0c 435 Gene3D G3DSA:3.20.20.140 75 347 1.2E-49 T 28-03-2018 CNX65_RS15475 53f24f8a9ac86efd991b201350051c0c 435 Gene3D G3DSA:2.30.40.10 348 418 8.0E-16 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS15475 53f24f8a9ac86efd991b201350051c0c 435 SUPERFAMILY SSF51556 59 361 1.47E-59 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS15475 53f24f8a9ac86efd991b201350051c0c 435 SUPERFAMILY SSF51338 5 59 2.53E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS15475 53f24f8a9ac86efd991b201350051c0c 435 SUPERFAMILY SSF51338 360 433 2.53E-26 T 28-03-2018 IPR011059 Metal-dependent hydrolase, composite domain GO:0016810 CNX65_RS15475 53f24f8a9ac86efd991b201350051c0c 435 Pfam PF01979 Amidohydrolase family 56 409 3.3E-35 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS11995 052f03c63210f93f2306a0497eda69c2 160 Gene3D G3DSA:1.20.58.300 3 132 9.8E-14 T 28-03-2018 CNX65_RS11995 052f03c63210f93f2306a0497eda69c2 160 Pfam PF05130 FlgN protein 2 147 9.7E-12 T 28-03-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 CNX65_RS10950 39546bfb03980a2622d3c8d52c913be9 309 Gene3D G3DSA:3.40.50.410 60 245 1.6E-16 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS10950 39546bfb03980a2622d3c8d52c913be9 309 Pfam PF01882 Protein of unknown function DUF58 48 132 2.5E-17 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CNX65_RS11245 67f1d6b8975c4d56de8395efbd58dd42 134 SUPERFAMILY SSF52172 1 119 5.69E-28 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS11245 67f1d6b8975c4d56de8395efbd58dd42 134 Pfam PF00072 Response regulator receiver domain 7 109 1.0E-18 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS11245 67f1d6b8975c4d56de8395efbd58dd42 134 Gene3D G3DSA:3.40.50.2300 1 121 6.5E-26 T 28-03-2018 CNX65_RS11245 67f1d6b8975c4d56de8395efbd58dd42 134 SMART SM00448 4 113 7.0E-26 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS12415 36be00192ec217eae5e646bf2a39e474 308 Gene3D G3DSA:1.10.10.10 2 84 9.2E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12415 36be00192ec217eae5e646bf2a39e474 308 Gene3D G3DSA:3.40.190.10 89 186 4.6E-23 T 28-03-2018 CNX65_RS12415 36be00192ec217eae5e646bf2a39e474 308 Gene3D G3DSA:3.40.190.10 187 267 4.1E-15 T 28-03-2018 CNX65_RS12415 36be00192ec217eae5e646bf2a39e474 308 SUPERFAMILY SSF46785 2 112 6.03E-25 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS12415 36be00192ec217eae5e646bf2a39e474 308 SUPERFAMILY SSF53850 89 299 6.03E-32 T 28-03-2018 CNX65_RS12415 36be00192ec217eae5e646bf2a39e474 308 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 4 62 1.4E-19 T 28-03-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 CNX65_RS12415 36be00192ec217eae5e646bf2a39e474 308 Pfam PF03466 LysR substrate binding domain 88 296 5.4E-31 T 28-03-2018 IPR005119 LysR, substrate-binding CNX65_RS34950 b225d66cdb5b78ee0fac00fefc6a4951 193 Hamap MF_00758 UPF0301 protein YqgE [yqgE]. 9 190 25.893 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 CNX65_RS34950 b225d66cdb5b78ee0fac00fefc6a4951 193 Pfam PF02622 Uncharacterized ACR, COG1678 20 177 6.3E-37 T 28-03-2018 IPR003774 Protein of unknown function UPF0301 CNX65_RS34950 b225d66cdb5b78ee0fac00fefc6a4951 193 Gene3D G3DSA:3.40.1740.10 5 91 4.0E-18 T 28-03-2018 CNX65_RS34950 b225d66cdb5b78ee0fac00fefc6a4951 193 Gene3D G3DSA:3.40.1740.10 105 181 2.2E-9 T 28-03-2018 CNX65_RS34950 b225d66cdb5b78ee0fac00fefc6a4951 193 SUPERFAMILY SSF143456 9 187 1.31E-48 T 28-03-2018 CNX65_RS05075 23bf906e1d8fcb041efa880ae8561773 256 SUPERFAMILY SSF56281 1 250 3.93E-48 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05075 23bf906e1d8fcb041efa880ae8561773 256 SMART SM00849 18 223 4.1E-9 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05075 23bf906e1d8fcb041efa880ae8561773 256 Pfam PF12706 Beta-lactamase superfamily domain 30 223 1.3E-21 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS05075 23bf906e1d8fcb041efa880ae8561773 256 Gene3D G3DSA:3.60.15.10 1 255 1.3E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS00250 1183666123ba8f8c8f8c83d10468aa21 544 Pfam PF13482 RNase_H superfamily 447 530 1.3E-11 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS00250 1183666123ba8f8c8f8c83d10468aa21 544 SUPERFAMILY SSF53098 449 529 1.26E-5 T 28-03-2018 IPR012337 Ribonuclease H-like domain GO:0003676 CNX65_RS00250 1183666123ba8f8c8f8c83d10468aa21 544 TIGRFAM TIGR03491 TIGR03491: putative RecB family nuclease, TM0106 family 13 530 1.4E-62 T 28-03-2018 IPR019993 RecB family nuclease, TM0106, putative CNX65_RS21155 720e11aba87dd86f16d581b20399622e 111 Gene3D G3DSA:1.10.10.10 4 102 2.8E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21155 720e11aba87dd86f16d581b20399622e 111 SMART SM00418 11 89 1.9E-21 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21155 720e11aba87dd86f16d581b20399622e 111 SUPERFAMILY SSF46785 7 87 2.13E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21155 720e11aba87dd86f16d581b20399622e 111 Pfam PF12840 Helix-turn-helix domain 11 68 2.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS21155 720e11aba87dd86f16d581b20399622e 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 13 28 1.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21155 720e11aba87dd86f16d581b20399622e 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 60 75 1.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS21155 720e11aba87dd86f16d581b20399622e 111 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 45 60 1.8E-8 T 28-03-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 CNX65_RS20375 81aed5dac679c572b7ec5e3ed6f54eac 359 Gene3D G3DSA:1.10.101.10 120 192 6.5E-10 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS20375 81aed5dac679c572b7ec5e3ed6f54eac 359 Pfam PF01471 Putative peptidoglycan binding domain 130 183 1.5E-6 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS20375 81aed5dac679c572b7ec5e3ed6f54eac 359 SUPERFAMILY SSF47090 120 190 8.32E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS17515 d26b88230393a3e026c3a376ba871458 188 Pfam PF11290 Protein of unknown function (DUF3090) 6 176 2.3E-72 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CNX65_RS17515 d26b88230393a3e026c3a376ba871458 188 TIGRFAM TIGR03847 TIGR03847: conserved hypothetical protein 5 180 3.0E-82 T 28-03-2018 IPR021441 Protein of unknown function DUF3090 CNX65_RS29925 8f3a997acefbdc50d4ebade43946b70c 105 Pfam PF01910 Thiamine-binding protein 3 93 1.0E-32 T 28-03-2018 IPR002767 Thiamine-binding protein CNX65_RS29925 8f3a997acefbdc50d4ebade43946b70c 105 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 2 95 5.8E-19 T 28-03-2018 IPR002767 Thiamine-binding protein CNX65_RS29925 8f3a997acefbdc50d4ebade43946b70c 105 SUPERFAMILY SSF89957 1 96 6.41E-31 T 28-03-2018 IPR029756 MTH1187/YkoF-like CNX65_RS29925 8f3a997acefbdc50d4ebade43946b70c 105 Gene3D G3DSA:3.30.70.930 1 100 1.1E-37 T 28-03-2018 IPR029756 MTH1187/YkoF-like CNX65_RS30140 e995f4b10405aab68ad208802daec105 178 Gene3D G3DSA:3.90.79.10 1 178 1.3E-31 T 28-03-2018 CNX65_RS30140 e995f4b10405aab68ad208802daec105 178 SUPERFAMILY SSF55811 2 173 1.49E-37 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS30140 e995f4b10405aab68ad208802daec105 178 Pfam PF00293 NUDIX domain 41 157 8.6E-9 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS15280 58ad13adfa46c850c106efade0efc17f 585 Gene3D G3DSA:2.160.10.10 470 566 3.6E-9 T 28-03-2018 CNX65_RS15280 58ad13adfa46c850c106efade0efc17f 585 SUPERFAMILY SSF51161 468 542 3.01E-9 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS33050 d8f9c4b6e02b09fd177b081214d667bb 99 Gene3D G3DSA:1.20.1560.10 7 81 9.6E-4 T 28-03-2018 CNX65_RS33050 d8f9c4b6e02b09fd177b081214d667bb 99 Pfam PF14012 Protein of unknown function (DUF4229) 11 71 9.5E-14 T 28-03-2018 IPR025323 Protein of unknown function DUF4229 CNX65_RS03110 70a4b94bb44870ce27aa142360ecf6ee 188 SUPERFAMILY SSF100950 9 182 6.14E-34 T 28-03-2018 CNX65_RS03110 70a4b94bb44870ce27aa142360ecf6ee 188 Gene3D G3DSA:3.40.50.10420 2 185 1.1E-42 T 28-03-2018 CNX65_RS03110 70a4b94bb44870ce27aa142360ecf6ee 188 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 42 179 7.0E-32 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CNX65_RS03110 70a4b94bb44870ce27aa142360ecf6ee 188 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 6 179 5.4E-28 T 28-03-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase CNX65_RS03285 733d372ab392f5c05cd625e0414bc8f9 175 Pfam PF14124 Domain of unknown function (DUF4291) 6 171 9.5E-53 T 28-03-2018 IPR025633 Protein of unknown function DUF4291 CNX65_RS34415 3e5bfe643ff2b92bdb55a8f2ddd66be7 247 Pfam PF06724 Domain of Unknown Function (DUF1206) 177 244 7.0E-16 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CNX65_RS34415 3e5bfe643ff2b92bdb55a8f2ddd66be7 247 Pfam PF06724 Domain of Unknown Function (DUF1206) 85 151 1.5E-12 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CNX65_RS34415 3e5bfe643ff2b92bdb55a8f2ddd66be7 247 Pfam PF06724 Domain of Unknown Function (DUF1206) 2 65 2.4E-17 T 28-03-2018 IPR009597 Domain of unknown function DUF1206 CNX65_RS14725 b80380afe277a080521b0858f336d741 649 Pfam PF10022 Uncharacterized protein conserved in bacteria (DUF2264) 15 362 5.4E-112 T 28-03-2018 IPR016624 Uncharacterised conserved protein UCP014753 CNX65_RS12100 113b85c9d7d222973bcd70722923aa4c 289 Gene3D G3DSA:1.10.260.40 12 81 1.4E-14 T 28-03-2018 CNX65_RS12100 113b85c9d7d222973bcd70722923aa4c 289 SMART SM00530 19 91 5.4E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS12100 113b85c9d7d222973bcd70722923aa4c 289 Pfam PF13560 Helix-turn-helix domain 15 94 2.9E-13 T 28-03-2018 CNX65_RS12100 113b85c9d7d222973bcd70722923aa4c 289 SUPERFAMILY SSF47413 32 87 5.63E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS12100 113b85c9d7d222973bcd70722923aa4c 289 Gene3D G3DSA:3.40.50.620 82 255 8.8E-4 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS21205 dad3024e4ea474ed2e5b76800b6fd070 159 Pfam PF16571 FBP C-terminal treble-clef zinc-finger 8 157 2.3E-59 T 28-03-2018 IPR032330 Elongation factor G-binding protein, C-terminal treble-clef zinc-finger CNX65_RS19500 83a143b670d056cb864ef030e10b8ced 224 SUPERFAMILY SSF52266 30 219 5.04E-36 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS19500 83a143b670d056cb864ef030e10b8ced 224 Gene3D G3DSA:3.40.50.1110 32 223 2.8E-30 T 28-03-2018 CNX65_RS19500 83a143b670d056cb864ef030e10b8ced 224 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 36 207 6.6E-24 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS06925 ddfb199b7da5f47a4080f407f70eaeaf 502 SUPERFAMILY SSF51905 10 319 4.4E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06925 ddfb199b7da5f47a4080f407f70eaeaf 502 SUPERFAMILY SSF51905 442 481 4.4E-64 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06925 ddfb199b7da5f47a4080f407f70eaeaf 502 ProSitePatterns PS00982 Bacterial-type phytoene dehydrogenase signature. 452 472 - T 28-03-2018 IPR008150 Phytoene dehydrogenase, bacterial-type, conserved site CNX65_RS06925 ddfb199b7da5f47a4080f407f70eaeaf 502 Pfam PF01593 Flavin containing amine oxidoreductase 18 480 2.6E-41 T 28-03-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 CNX65_RS06925 ddfb199b7da5f47a4080f407f70eaeaf 502 Gene3D G3DSA:3.50.50.60 4 486 2.3E-35 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS06925 ddfb199b7da5f47a4080f407f70eaeaf 502 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 11 483 1.6E-156 T 28-03-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 CNX65_RS27935 a26b8100a0177417621117bfdb8e1ebf 367 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 10 279 15.274 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CNX65_RS27935 a26b8100a0177417621117bfdb8e1ebf 367 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 142 154 - T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CNX65_RS27935 a26b8100a0177417621117bfdb8e1ebf 367 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 13 278 2.9E-45 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CNX65_RS27935 a26b8100a0177417621117bfdb8e1ebf 367 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 15 273 3.5E-64 T 28-03-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0009249|GO:0016020|GO:0016757|GO:0042158 CNX65_RS23335 aa57f1dd1c9f6089a6b9408fb475455a 538 Gene3D G3DSA:3.40.605.10 32 292 3.6E-73 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS23335 aa57f1dd1c9f6089a6b9408fb475455a 538 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 274 281 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS23335 aa57f1dd1c9f6089a6b9408fb475455a 538 Pfam PF00171 Aldehyde dehydrogenase family 48 502 1.5E-137 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS23335 aa57f1dd1c9f6089a6b9408fb475455a 538 Gene3D G3DSA:3.40.309.10 293 469 1.7E-62 T 28-03-2018 CNX65_RS23335 aa57f1dd1c9f6089a6b9408fb475455a 538 SUPERFAMILY SSF53720 44 504 3.01E-138 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS22085 0ae0ce1094f5984a6880f968847e7142 175 SUPERFAMILY SSF51735 14 113 9.0E-10 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS22085 0ae0ce1094f5984a6880f968847e7142 175 Gene3D G3DSA:3.40.50.720 10 121 7.7E-10 T 28-03-2018 CNX65_RS07955 f6217c6ba914492ff449a16a74bc080b 183 Pfam PF12079 Protein of unknown function (DUF3558) 14 178 7.2E-10 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS25295 8a77088bf29bdaaf507dabf10214263a 496 SUPERFAMILY SSF81606 289 493 6.8E-11 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS25295 8a77088bf29bdaaf507dabf10214263a 496 Gene3D G3DSA:3.30.450.20 35 173 2.4E-4 T 28-03-2018 CNX65_RS25295 8a77088bf29bdaaf507dabf10214263a 496 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 302 493 6.5E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS25295 8a77088bf29bdaaf507dabf10214263a 496 SMART SM00331 272 494 8.4E-40 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS25295 8a77088bf29bdaaf507dabf10214263a 496 Gene3D G3DSA:3.60.40.10 238 495 1.1E-32 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS17090 4a771f4a9a1347c14470fbd5d6b86da5 393 Gene3D G3DSA:2.160.20.80 30 253 2.0E-4 T 28-03-2018 CNX65_RS26225 732bc782ad7aee545e7a7b3868303e02 314 Gene3D G3DSA:3.40.30.10 132 225 4.1E-10 T 28-03-2018 CNX65_RS26225 732bc782ad7aee545e7a7b3868303e02 314 Pfam PF06999 Sucrase/ferredoxin-like 25 218 1.7E-14 T 28-03-2018 IPR009737 Thioredoxin-like ferredoxin CNX65_RS26225 732bc782ad7aee545e7a7b3868303e02 314 SUPERFAMILY SSF52833 137 220 4.47E-6 T 28-03-2018 IPR012336 Thioredoxin-like fold CNX65_RS07855 e4d867d8825aaa3aaad6d5db528fb2a6 275 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 50 262 1.3E-19 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS07855 e4d867d8825aaa3aaad6d5db528fb2a6 275 SUPERFAMILY SSF52266 49 271 1.08E-51 T 28-03-2018 IPR013830 SGNH hydrolase-type esterase domain CNX65_RS07855 e4d867d8825aaa3aaad6d5db528fb2a6 275 Gene3D G3DSA:3.40.50.1110 47 273 2.7E-32 T 28-03-2018 CNX65_RS16750 0d28c987eccd8c39943f631b48ef86cd 279 Gene3D G3DSA:3.40.50.720 1 277 8.6E-27 T 28-03-2018 CNX65_RS16750 0d28c987eccd8c39943f631b48ef86cd 279 Pfam PF13460 NAD(P)H-binding 6 179 3.2E-19 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS16750 0d28c987eccd8c39943f631b48ef86cd 279 SUPERFAMILY SSF51735 2 275 1.86E-50 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS13170 3e480529feb1ddbb1e2369a477289487 171 Gene3D G3DSA:3.40.220.10 2 171 2.7E-59 T 28-03-2018 CNX65_RS13170 3e480529feb1ddbb1e2369a477289487 171 SUPERFAMILY SSF52949 3 169 3.87E-52 T 28-03-2018 CNX65_RS13170 3e480529feb1ddbb1e2369a477289487 171 Pfam PF01661 Macro domain 20 137 7.0E-39 T 28-03-2018 IPR002589 Macro domain CNX65_RS13170 3e480529feb1ddbb1e2369a477289487 171 SMART SM00506 3 137 3.0E-47 T 28-03-2018 IPR002589 Macro domain CNX65_RS13870 f412cdd7e97ce9cab8ba3a0bf5eadd28 70 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 6 68 1.9E-18 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS13870 f412cdd7e97ce9cab8ba3a0bf5eadd28 70 Gene3D G3DSA:1.10.260.40 3 70 5.3E-10 T 28-03-2018 CNX65_RS13870 f412cdd7e97ce9cab8ba3a0bf5eadd28 70 SMART SM00530 6 62 1.4E-6 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS13870 f412cdd7e97ce9cab8ba3a0bf5eadd28 70 SUPERFAMILY SSF47413 2 68 2.06E-15 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS01590 10fb5d899fb935c4c0bdbf44b28a8e4b 337 TIGRFAM TIGR03883 DUF2342_F420: uncharacterized protein, coenzyme F420 biosynthesis associated 10 335 2.4E-116 T 28-03-2018 IPR022454 Conserved hypothetical protein CHP03883, F420 biosynthesis associated CNX65_RS01590 10fb5d899fb935c4c0bdbf44b28a8e4b 337 SUPERFAMILY SSF55486 10 335 3.52E-101 T 28-03-2018 CNX65_RS01590 10fb5d899fb935c4c0bdbf44b28a8e4b 337 Pfam PF10103 Zincin-like metallopeptidase 10 332 1.2E-109 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CNX65_RS01590 10fb5d899fb935c4c0bdbf44b28a8e4b 337 TIGRFAM TIGR03624 TIGR03624: putative hydrolase 10 335 1.4E-100 T 28-03-2018 IPR018766 Zinicin-like metallopeptidase type 2 CNX65_RS02850 17f3ed63903e09e435e1b5ead11033fa 438 SUPERFAMILY SSF53067 3 155 3.45E-16 T 28-03-2018 CNX65_RS02850 17f3ed63903e09e435e1b5ead11033fa 438 Gene3D G3DSA:3.30.420.40 1 164 7.6E-16 T 28-03-2018 CNX65_RS02850 17f3ed63903e09e435e1b5ead11033fa 438 Pfam PF00012 Hsp70 protein 84 340 2.8E-15 T 28-03-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 CNX65_RS02850 17f3ed63903e09e435e1b5ead11033fa 438 Gene3D G3DSA:3.30.420.40 165 324 4.5E-11 T 28-03-2018 CNX65_RS02850 17f3ed63903e09e435e1b5ead11033fa 438 SUPERFAMILY SSF53067 164 342 1.15E-18 T 28-03-2018 CNX65_RS21085 9eacce18aec8bb93dd11224f5976bdf4 290 Gene3D G3DSA:3.40.50.1820 2 282 1.4E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21085 9eacce18aec8bb93dd11224f5976bdf4 290 Pfam PF07859 alpha/beta hydrolase fold 62 259 8.8E-32 T 28-03-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0008152|GO:0016787 CNX65_RS21085 9eacce18aec8bb93dd11224f5976bdf4 290 SUPERFAMILY SSF53474 48 275 5.99E-39 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS15565 5a20d8b994b1f0ec649f801d58cf9b06 373 SUPERFAMILY SSF103473 4 366 9.29E-41 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS15565 5a20d8b994b1f0ec649f801d58cf9b06 373 Gene3D G3DSA:1.20.1250.20 1 180 2.6E-18 T 28-03-2018 CNX65_RS15565 5a20d8b994b1f0ec649f801d58cf9b06 373 Gene3D G3DSA:1.20.1250.20 189 373 6.9E-12 T 28-03-2018 CNX65_RS15565 5a20d8b994b1f0ec649f801d58cf9b06 373 Pfam PF07690 Major Facilitator Superfamily 8 302 3.1E-26 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS08320 7fac822bfa9ca9439df87940b5f53102 372 SUPERFAMILY SSF63825 24 205 7.85E-10 T 28-03-2018 CNX65_RS08320 7fac822bfa9ca9439df87940b5f53102 372 PRINTS PR01217 Proline rich extensin signature 246 262 5.8E-9 T 28-03-2018 CNX65_RS08320 7fac822bfa9ca9439df87940b5f53102 372 PRINTS PR01217 Proline rich extensin signature 279 300 5.8E-9 T 28-03-2018 CNX65_RS08320 7fac822bfa9ca9439df87940b5f53102 372 PRINTS PR01217 Proline rich extensin signature 303 319 5.8E-9 T 28-03-2018 CNX65_RS08320 7fac822bfa9ca9439df87940b5f53102 372 PRINTS PR01217 Proline rich extensin signature 266 278 5.8E-9 T 28-03-2018 CNX65_RS08320 7fac822bfa9ca9439df87940b5f53102 372 Gene3D G3DSA:2.120.10.30 3 258 2.6E-9 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS23035 ca8e906654caa5ad6b00bdbef381097c 126 Pfam PF03995 Peptidase inhibitor family I36 41 103 9.8E-8 T 28-03-2018 CNX65_RS23035 ca8e906654caa5ad6b00bdbef381097c 126 Gene3D G3DSA:2.60.20.10 33 126 8.4E-6 T 28-03-2018 CNX65_RS17020 decc3199030775e9ee647538fb71b377 1092 Gene3D G3DSA:1.20.5.1230 242 402 0.0014 T 28-03-2018 CNX65_RS17020 decc3199030775e9ee647538fb71b377 1092 Gene3D G3DSA:1.20.5.1230 403 576 0.0062 T 28-03-2018 CNX65_RS30320 96ecb4019cf2f9cff49d0de94cb3abfc 253 Gene3D G3DSA:1.20.1260.10 67 248 6.1E-49 T 28-03-2018 IPR012347 Ferritin-related CNX65_RS30320 96ecb4019cf2f9cff49d0de94cb3abfc 253 Pfam PF03713 Domain of unknown function (DUF305) 75 244 3.6E-45 T 28-03-2018 IPR005183 Domain of unknown function DUF305 CNX65_RS23250 632d9ef7d3068f7a3bc707b3d9a71a22 245 Gene3D G3DSA:3.60.110.10 2 235 7.4E-69 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS23250 632d9ef7d3068f7a3bc707b3d9a71a22 245 Pfam PF00795 Carbon-nitrogen hydrolase 9 212 9.5E-47 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS23250 632d9ef7d3068f7a3bc707b3d9a71a22 245 ProSitePatterns PS01227 Uncharacterized protein family UPF0012 signature. 120 140 - T 28-03-2018 IPR001110 Uncharacterised protein family UPF0012, conserved site CNX65_RS23250 632d9ef7d3068f7a3bc707b3d9a71a22 245 SUPERFAMILY SSF56317 6 233 3.66E-69 T 28-03-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807|GO:0016810 CNX65_RS22715 06b07225a74b09397c7ca9e4fa81837d 425 Gene3D G3DSA:1.20.1250.20 13 216 2.1E-22 T 28-03-2018 CNX65_RS22715 06b07225a74b09397c7ca9e4fa81837d 425 Pfam PF07690 Major Facilitator Superfamily 29 371 2.5E-23 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS22715 06b07225a74b09397c7ca9e4fa81837d 425 SUPERFAMILY SSF103473 21 418 4.84E-45 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS22715 06b07225a74b09397c7ca9e4fa81837d 425 Gene3D G3DSA:1.20.1250.20 220 418 7.2E-21 T 28-03-2018 CNX65_RS16970 833d74817b95ed4c822e9abed80f0807 196 Gene3D G3DSA:2.30.110.10 80 191 0.0012 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS02405 a1357524ce7d4eabdacf6447c80f2a2e 270 SUPERFAMILY SSF109854 26 158 2.84E-8 T 28-03-2018 IPR034660 DinB/YfiT-like putative metalloenzymes CNX65_RS02405 a1357524ce7d4eabdacf6447c80f2a2e 270 Gene3D G3DSA:1.20.120.450 11 160 1.2E-13 T 28-03-2018 CNX65_RS02405 a1357524ce7d4eabdacf6447c80f2a2e 270 TIGRFAM TIGR03083 TIGR03083: uncharacterized Actinobacterial protein TIGR03083 26 209 1.6E-16 T 28-03-2018 IPR017517 Conserved hypothetical protein CHP03083, actinobacterial-type CNX65_RS02405 a1357524ce7d4eabdacf6447c80f2a2e 270 Pfam PF11716 Mycothiol maleylpyruvate isomerase N-terminal domain 26 154 5.8E-18 T 28-03-2018 IPR024344 Mycothiol-dependent maleylpyruvate isomerase, metal-binding domain GO:0046872 CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 Pfam PF02470 MlaD protein 32 103 3.5E-13 T 28-03-2018 IPR003399 Mce/MlaD CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 Gene3D G3DSA:1.20.1170.10 123 294 1.2E-4 T 28-03-2018 CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 TIGRFAM TIGR00996 Mtu_fam_mce: virulence factor Mce family protein 10 285 5.5E-59 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 290 309 2.4E-11 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 121 145 2.4E-11 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 239 258 2.4E-11 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 170 188 2.4E-11 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS11020 f2fa6b5ae52daeef5941443543bcfa0d 319 PRINTS PR01782 Mycobacterial cell entry (MCE) protein signature 83 99 2.4E-11 T 28-03-2018 IPR005693 Virulence factor Mce protein CNX65_RS08695 e4ce14e1e2af245745a3343ce0d0a5e5 406 Gene3D G3DSA:3.40.50.2000 189 396 4.4E-12 T 28-03-2018 CNX65_RS08695 e4ce14e1e2af245745a3343ce0d0a5e5 406 SUPERFAMILY SSF53756 74 398 1.06E-15 T 28-03-2018 CNX65_RS34845 0873fdb6ce976f0f238aec1fb28a66b2 826 Gene3D G3DSA:2.160.20.80 82 545 2.4E-7 T 28-03-2018 CNX65_RS02470 fe2b064f72f40758d5c078a24f58fe6c 309 Pfam PF11228 Protein of unknown function (DUF3027) 36 227 4.3E-82 T 28-03-2018 IPR021391 Protein of unknown function DUF3027 CNX65_RS19495 f6968f7be0746ff066c9e128b1db3238 175 Gene3D G3DSA:1.20.1250.20 1 163 7.2E-12 T 28-03-2018 CNX65_RS19495 f6968f7be0746ff066c9e128b1db3238 175 Pfam PF07690 Major Facilitator Superfamily 7 94 2.6E-9 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS19495 f6968f7be0746ff066c9e128b1db3238 175 SUPERFAMILY SSF103473 6 151 8.76E-11 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS20470 83890e4dd736511de66a2748d5325bf0 309 Gene3D G3DSA:3.40.50.1820 32 307 1.8E-46 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20470 83890e4dd736511de66a2748d5325bf0 309 SUPERFAMILY SSF53474 35 306 5.13E-55 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS20470 83890e4dd736511de66a2748d5325bf0 309 PRINTS PR00412 Epoxide hydrolase signature 127 140 7.7E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20470 83890e4dd736511de66a2748d5325bf0 309 PRINTS PR00412 Epoxide hydrolase signature 64 82 7.7E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20470 83890e4dd736511de66a2748d5325bf0 309 PRINTS PR00412 Epoxide hydrolase signature 284 306 7.7E-5 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS20470 83890e4dd736511de66a2748d5325bf0 309 Pfam PF12697 Alpha/beta hydrolase family 60 300 1.2E-20 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 15 28 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 36 59 1.4E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 SUPERFAMILY SSF46689 4 77 4.99E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 Gene3D G3DSA:1.10.357.10 69 190 5.4E-17 T 28-03-2018 CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 Pfam PF00440 Bacterial regulatory proteins, tetR family 15 61 1.0E-10 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 SUPERFAMILY SSF48498 94 186 9.56E-10 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 Gene3D G3DSA:1.10.10.60 9 49 6.7E-16 T 28-03-2018 CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 Pfam PF13305 WHG domain 94 164 4.3E-7 T 28-03-2018 IPR025996 WHG domain CNX65_RS11275 8f529424ca6007873ccffdb383f6cd57 195 Gene3D G3DSA:1.10.10.60 50 68 7.1E-10 T 28-03-2018 CNX65_RS18170 4d72c0915fd1a834d812565676984eef 255 Pfam PF02361 Cobalt transport protein 13 216 2.5E-26 T 28-03-2018 IPR003339 ABC/ECF transporter, transmembrane component CNX65_RS18170 4d72c0915fd1a834d812565676984eef 255 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 22 215 3.8E-36 T 28-03-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 CNX65_RS18130 f03fa9aaeb11b631276ae85303b3635b 379 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 33 299 1.8E-68 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS18130 f03fa9aaeb11b631276ae85303b3635b 379 SUPERFAMILY SSF53686 22 309 9.95E-73 T 28-03-2018 IPR001926 Tryptophan synthase beta subunit-like PLP-dependent enzyme CNX65_RS18130 f03fa9aaeb11b631276ae85303b3635b 379 Gene3D G3DSA:3.40.50.1100 147 321 1.0E-36 T 28-03-2018 CNX65_RS18130 f03fa9aaeb11b631276ae85303b3635b 379 Gene3D G3DSA:3.40.50.1100 44 146 2.2E-28 T 28-03-2018 CNX65_RS13725 3a7743c1cebf915058a6c9ebe43b0745 240 Pfam PF00753 Metallo-beta-lactamase superfamily 12 217 1.9E-26 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS13725 3a7743c1cebf915058a6c9ebe43b0745 240 Gene3D G3DSA:3.60.15.10 1 239 3.9E-37 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS13725 3a7743c1cebf915058a6c9ebe43b0745 240 SUPERFAMILY SSF56281 2 231 2.57E-43 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS13725 3a7743c1cebf915058a6c9ebe43b0745 240 SMART SM00849 14 217 1.3E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS12195 58a0540c605df48a0ee2a4efceecca55 341 Pfam PF00296 Luciferase-like monooxygenase 29 295 4.8E-28 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS12195 58a0540c605df48a0ee2a4efceecca55 341 Gene3D G3DSA:3.20.20.30 4 334 3.4E-50 T 28-03-2018 CNX65_RS12195 58a0540c605df48a0ee2a4efceecca55 341 SUPERFAMILY SSF51679 14 326 6.67E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS07605 d440992c7822473b406a9755af43055f 228 Pfam PF12079 Protein of unknown function (DUF3558) 46 219 1.2E-22 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS14110 6d1ee89e03f7c11430fe32dabb84f1be 169 Pfam PF08281 Sigma-70, region 4 108 158 1.9E-9 T 28-03-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14110 6d1ee89e03f7c11430fe32dabb84f1be 169 SUPERFAMILY SSF88659 98 163 4.11E-12 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS14110 6d1ee89e03f7c11430fe32dabb84f1be 169 Gene3D G3DSA:1.10.1740.10 20 97 7.5E-6 T 28-03-2018 CNX65_RS14110 6d1ee89e03f7c11430fe32dabb84f1be 169 Gene3D G3DSA:1.10.10.10 104 167 4.2E-11 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32670 58fbca41be0c028fc0a97fcb6fc8de26 144 Gene3D G3DSA:1.10.10.10 15 94 9.2E-19 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32670 58fbca41be0c028fc0a97fcb6fc8de26 144 SUPERFAMILY SSF46785 27 105 5.44E-18 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS32670 58fbca41be0c028fc0a97fcb6fc8de26 144 SMART SM00345 33 92 3.8E-11 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS32670 58fbca41be0c028fc0a97fcb6fc8de26 144 Pfam PF00392 Bacterial regulatory proteins, gntR family 31 92 6.5E-14 T 28-03-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 CNX65_RS28895 6deec4dc224070ec3f63c1fe797eec5a 403 Gene3D G3DSA:2.30.42.10 21 222 5.6E-13 T 28-03-2018 CNX65_RS28895 6deec4dc224070ec3f63c1fe797eec5a 403 Pfam PF02163 Peptidase family M50 10 354 9.9E-49 T 28-03-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889|Reactome: R-MMU-8963889 CNX65_RS28895 6deec4dc224070ec3f63c1fe797eec5a 403 SUPERFAMILY SSF50156 159 233 4.47E-9 T 28-03-2018 IPR001478 PDZ domain GO:0005515 CNX65_RS11985 63837f594ceca677756764e767f6f535 386 PRINTS PR00207 Flagellin signature 37 54 7.9E-22 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CNX65_RS11985 63837f594ceca677756764e767f6f535 386 PRINTS PR00207 Flagellin signature 112 135 7.9E-22 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CNX65_RS11985 63837f594ceca677756764e767f6f535 386 PRINTS PR00207 Flagellin signature 76 95 7.9E-22 T 28-03-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 CNX65_RS11985 63837f594ceca677756764e767f6f535 386 Gene3D G3DSA:1.20.1330.10 40 358 2.2E-61 T 28-03-2018 CNX65_RS11985 63837f594ceca677756764e767f6f535 386 SUPERFAMILY SSF64518 1 386 5.1E-93 T 28-03-2018 CNX65_RS11985 63837f594ceca677756764e767f6f535 386 Pfam PF00700 Bacterial flagellin C-terminal helical region 300 385 4.6E-30 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CNX65_RS11985 63837f594ceca677756764e767f6f535 386 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 141 1.0E-40 T 28-03-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 CNX65_RS18460 647204285a5a50d542d8bff7dfba1094 280 Gene3D G3DSA:3.80.10.10 44 275 1.4E-4 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CNX65_RS03375 f05c27d864d0deee0e0d2ffab7151281 307 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 116 307 2.2E-25 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03375 f05c27d864d0deee0e0d2ffab7151281 307 Gene3D G3DSA:1.10.3720.10 26 296 3.4E-38 T 28-03-2018 CNX65_RS03375 f05c27d864d0deee0e0d2ffab7151281 307 SUPERFAMILY SSF161098 95 288 3.01E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03375 f05c27d864d0deee0e0d2ffab7151281 307 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 24 60 6.3E-6 T 28-03-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain CNX65_RS14440 60dcde4d5ec987a18983fd8825962f5e 471 Gene3D G3DSA:3.40.50.2300 212 418 1.8E-12 T 28-03-2018 CNX65_RS14440 60dcde4d5ec987a18983fd8825962f5e 471 Gene3D G3DSA:3.40.50.2300 90 211 0.0074 T 28-03-2018 CNX65_RS14440 60dcde4d5ec987a18983fd8825962f5e 471 Pfam PF01094 Receptor family ligand binding region 116 458 3.6E-9 T 28-03-2018 IPR001828 Receptor, ligand binding region CNX65_RS14440 60dcde4d5ec987a18983fd8825962f5e 471 SUPERFAMILY SSF53822 140 462 7.85E-18 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS26660 f7e1e6606abfa80f24f8a279dabd9d61 157 SUPERFAMILY SSF103256 1 136 7.98E-46 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CNX65_RS26660 f7e1e6606abfa80f24f8a279dabd9d61 157 Pfam PF02577 Bifunctional nuclease 6 127 7.6E-44 T 28-03-2018 IPR003729 Bifunctional nuclease domain GO:0004518 CNX65_RS24125 7733be86ee3c36b70e41be2d4a308bc4 232 Pfam PF01048 Phosphorylase superfamily 2 220 1.9E-26 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CNX65_RS24125 7733be86ee3c36b70e41be2d4a308bc4 232 Gene3D G3DSA:3.40.50.1580 1 229 2.1E-33 T 28-03-2018 CNX65_RS24125 7733be86ee3c36b70e41be2d4a308bc4 232 SUPERFAMILY SSF53167 1 224 3.14E-44 T 28-03-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 CNX65_RS12985 41e6df0ac4e6399f471bc1e57997f2d7 281 Gene3D G3DSA:3.40.390.10 77 262 6.0E-5 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CNX65_RS12985 41e6df0ac4e6399f471bc1e57997f2d7 281 Pfam PF11350 Protein of unknown function (DUF3152) 81 280 2.3E-69 T 28-03-2018 IPR022603 Domain of unknown function DUF3152 CNX65_RS12985 41e6df0ac4e6399f471bc1e57997f2d7 281 SUPERFAMILY SSF55486 127 259 3.04E-12 T 28-03-2018 CNX65_RS04310 715ccc51cfd1fe7709e912aec0cddfb5 295 Pfam PF02104 SURF1 family 25 222 1.6E-26 T 28-03-2018 IPR002994 Surfeit locus 1/Shy1 GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 CNX65_RS12090 7dcd8240a7ee870345605d987b1f93b5 119 Pfam PF13564 DoxX-like family 7 113 2.0E-24 T 28-03-2018 IPR032808 DoxX family CNX65_RS07615 773cf0ebb02fee4c17ff75095d1294b5 113 Pfam PF03995 Peptidase inhibitor family I36 19 90 1.1E-14 T 28-03-2018 CNX65_RS09820 06602e8c5cce611303f667760436788e 132 Pfam PF17240 Family of unknown function (DUF5313) 3 127 8.8E-20 T 28-03-2018 IPR035197 Protein of unknown function DUF5313 CNX65_RS13690 cbedacb7dc779b66d981fa431f3d349a 206 Pfam PF01596 O-methyltransferase 12 185 8.2E-29 T 28-03-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 CNX65_RS13690 cbedacb7dc779b66d981fa431f3d349a 206 SUPERFAMILY SSF53335 19 205 1.91E-33 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS13690 cbedacb7dc779b66d981fa431f3d349a 206 Gene3D G3DSA:3.40.50.150 1 206 3.0E-31 T 28-03-2018 CNX65_RS12995 f8fc6d124fdf5eb2337adecf660f653f 850 Pfam PF13208 TerB N-terminal domain 158 356 6.1E-44 T 28-03-2018 IPR025266 TerB, N-terminal CNX65_RS12995 f8fc6d124fdf5eb2337adecf660f653f 850 Pfam PF15615 TerB-C domain 684 843 4.3E-11 T 28-03-2018 IPR028932 TerB-C domain CNX65_RS08200 6eeb583255e7c3648f157787cd6aed71 1056 SUPERFAMILY SSF52540 638 995 1.33E-36 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS08200 6eeb583255e7c3648f157787cd6aed71 1056 Gene3D G3DSA:3.40.50.300 33 315 0.0029 T 28-03-2018 CNX65_RS08200 6eeb583255e7c3648f157787cd6aed71 1056 Pfam PF01935 Domain of unknown function DUF87 649 710 3.3E-8 T 28-03-2018 IPR002789 Helicase HerA, central domain CNX65_RS08200 6eeb583255e7c3648f157787cd6aed71 1056 Gene3D G3DSA:3.40.50.300 499 1030 5.8E-24 T 28-03-2018 CNX65_RS08200 6eeb583255e7c3648f157787cd6aed71 1056 SMART SM00382 55 259 19.0 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS08200 6eeb583255e7c3648f157787cd6aed71 1056 SMART SM00382 666 1008 0.0071 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03640 d97d3fe2b3c183ead3904b3af637fcca 313 Pfam PF02646 RmuC family 59 263 4.9E-40 T 28-03-2018 IPR003798 DNA recombination RmuC CNX65_RS31820 73c3098e32516cc60205460f7f1926ac 261 Pfam PF06182 ABC-2 family transporter protein 52 259 8.6E-11 T 28-03-2018 IPR010390 Protein of unknown function DUF990 CNX65_RS27100 e224d6d7a1ae4e4df611780e0f5c1dd0 264 Gene3D G3DSA:3.40.50.1000 1 264 1.7E-31 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS27100 e224d6d7a1ae4e4df611780e0f5c1dd0 264 Pfam PF13242 HAD-hyrolase-like 185 256 9.6E-19 T 28-03-2018 CNX65_RS27100 e224d6d7a1ae4e4df611780e0f5c1dd0 264 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 11 232 2.7E-35 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CNX65_RS27100 e224d6d7a1ae4e4df611780e0f5c1dd0 264 PIRSF PIRSF000915 1 264 1.7E-62 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CNX65_RS27100 e224d6d7a1ae4e4df611780e0f5c1dd0 264 SUPERFAMILY SSF56784 6 256 7.78E-57 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS27100 e224d6d7a1ae4e4df611780e0f5c1dd0 264 Pfam PF13344 Haloacid dehalogenase-like hydrolase 10 110 2.2E-23 T 28-03-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA CNX65_RS13060 7dd177e90eee4c8b9d5fbd11205cbe5a 449 Gene3D G3DSA:3.40.190.10 54 222 8.3E-40 T 28-03-2018 CNX65_RS13060 7dd177e90eee4c8b9d5fbd11205cbe5a 449 Pfam PF01547 Bacterial extracellular solute-binding protein 58 343 1.5E-34 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS13060 7dd177e90eee4c8b9d5fbd11205cbe5a 449 SUPERFAMILY SSF53850 54 436 7.25E-69 T 28-03-2018 CNX65_RS13060 7dd177e90eee4c8b9d5fbd11205cbe5a 449 Gene3D G3DSA:3.40.190.10 223 396 1.2E-10 T 28-03-2018 CNX65_RS33245 84bdc58f17b1673762b4aa7f445157e3 286 Gene3D G3DSA:3.20.20.220 4 268 3.0E-28 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CNX65_RS33245 84bdc58f17b1673762b4aa7f445157e3 286 SUPERFAMILY SSF51730 18 279 1.29E-27 T 28-03-2018 IPR029041 FAD-linked oxidoreductase-like CNX65_RS16825 5274586b803f84f6a0ff9423bc8df302 303 SUPERFAMILY SSF56281 32 290 9.83E-41 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS16825 5274586b803f84f6a0ff9423bc8df302 303 Gene3D G3DSA:3.60.15.10 1 300 1.3E-49 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS16825 5274586b803f84f6a0ff9423bc8df302 303 Pfam PF00753 Metallo-beta-lactamase superfamily 62 275 1.6E-32 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS16825 5274586b803f84f6a0ff9423bc8df302 303 SMART SM00849 61 275 2.3E-23 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS14255 69746bd8e7e3ce5cf852252458ee52a4 253 PIRSF PIRSF006648 3 251 8.0E-20 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS14255 69746bd8e7e3ce5cf852252458ee52a4 253 Pfam PF01061 ABC-2 type transporter 18 218 2.5E-18 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS19490 34916a4d9c4fdbd29ac0815dd2c85088 272 Gene3D G3DSA:3.30.465.10 17 173 9.2E-30 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS19490 34916a4d9c4fdbd29ac0815dd2c85088 272 SUPERFAMILY SSF56176 9 134 1.03E-24 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS19490 34916a4d9c4fdbd29ac0815dd2c85088 272 Pfam PF01565 FAD binding domain 11 96 3.5E-13 T 28-03-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 CNX65_RS12650 6e0f2e07b25c5a64599100c5e06c8669 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 54 69 1.9E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS12650 6e0f2e07b25c5a64599100c5e06c8669 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 113 126 1.9E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS12650 6e0f2e07b25c5a64599100c5e06c8669 279 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 1.9E-7 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS12650 6e0f2e07b25c5a64599100c5e06c8669 279 SUPERFAMILY SSF53474 4 253 1.33E-43 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS12650 6e0f2e07b25c5a64599100c5e06c8669 279 Gene3D G3DSA:3.40.50.1820 2 73 9.1E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS12650 6e0f2e07b25c5a64599100c5e06c8669 279 Gene3D G3DSA:3.40.50.1820 74 259 1.7E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS12650 6e0f2e07b25c5a64599100c5e06c8669 279 Pfam PF00561 alpha/beta hydrolase fold 26 152 1.1E-25 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS10945 74e20dba167d6efc6bc4a0debe58ed1c 346 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 49 179 1.2E-59 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CNX65_RS10945 74e20dba167d6efc6bc4a0debe58ed1c 346 SUPERFAMILY SSF52540 17 300 3.78E-41 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS10945 74e20dba167d6efc6bc4a0debe58ed1c 346 PIRSF PIRSF002849 2 330 7.1E-134 T 28-03-2018 CNX65_RS10945 74e20dba167d6efc6bc4a0debe58ed1c 346 Gene3D G3DSA:1.10.8.300 208 325 5.3E-32 T 28-03-2018 CNX65_RS10945 74e20dba167d6efc6bc4a0debe58ed1c 346 Gene3D G3DSA:3.40.50.300 30 196 1.1E-24 T 28-03-2018 CNX65_RS14965 e395ae3feba9c73e2d2c4da2654bc800 245 Pfam PF01261 Xylose isomerase-like TIM barrel 65 200 2.7E-15 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS14965 e395ae3feba9c73e2d2c4da2654bc800 245 SUPERFAMILY SSF51658 8 237 9.95E-30 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS14965 e395ae3feba9c73e2d2c4da2654bc800 245 Gene3D G3DSA:3.20.20.150 1 245 1.1E-31 T 28-03-2018 CNX65_RS26980 46e5eeccb2089e9e15d5519d79516b38 345 Gene3D G3DSA:3.40.190.10 165 342 1.8E-25 T 28-03-2018 CNX65_RS26980 46e5eeccb2089e9e15d5519d79516b38 345 Gene3D G3DSA:3.40.190.10 52 164 1.0E-12 T 28-03-2018 CNX65_RS26980 46e5eeccb2089e9e15d5519d79516b38 345 Pfam PF09084 NMT1/THI5 like 68 279 7.0E-26 T 28-03-2018 IPR015168 SsuA/THI5-like CNX65_RS26980 46e5eeccb2089e9e15d5519d79516b38 345 SUPERFAMILY SSF53850 54 279 1.0E-37 T 28-03-2018 CNX65_RS19770 aba0689bbd137d4176e3965065a35cf3 393 SUPERFAMILY SSF140459 15 164 1.52E-8 T 28-03-2018 CNX65_RS19770 aba0689bbd137d4176e3965065a35cf3 393 Gene3D G3DSA:1.10.287.850 16 125 4.8E-8 T 28-03-2018 CNX65_RS06830 019d316720cb3fcd8cb350bfae31bfeb 343 Pfam PF00877 NlpC/P60 family 243 327 2.9E-18 T 28-03-2018 IPR000064 Endopeptidase, NLPC/P60 domain CNX65_RS06830 019d316720cb3fcd8cb350bfae31bfeb 343 Gene3D G3DSA:1.20.120.330 30 213 2.4E-6 T 28-03-2018 CNX65_RS06830 019d316720cb3fcd8cb350bfae31bfeb 343 SUPERFAMILY SSF54001 227 340 4.37E-29 T 28-03-2018 CNX65_RS06830 019d316720cb3fcd8cb350bfae31bfeb 343 Gene3D G3DSA:3.90.1720.10 227 342 2.6E-28 T 28-03-2018 CNX65_RS02185 ecad5e02de50365fbe08c6b8c64510d0 365 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 4 346 2.1E-71 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CNX65_RS02185 ecad5e02de50365fbe08c6b8c64510d0 365 Gene3D G3DSA:3.20.20.70 1 361 6.5E-124 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS02185 ecad5e02de50365fbe08c6b8c64510d0 365 SUPERFAMILY SSF51395 2 359 1.49E-115 T 28-03-2018 CNX65_RS31240 d9699ec019379c9d7f94d53146bc64cf 404 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 95 263 1.6E-35 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS31240 d9699ec019379c9d7f94d53146bc64cf 404 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 95 263 2.3E-41 T 28-03-2018 IPR004474 Cell envelope-related transcriptional attenuator domain CNX65_RS27420 f77f40378bd26fde507b0240e0045543 397 Pfam PF09594 Glycosyltransferase family 87 69 299 6.7E-52 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CNX65_RS15615 32ccf3acddde78924c79bae02115948a 109 SUPERFAMILY SSF103481 7 104 3.4E-12 T 28-03-2018 CNX65_RS15615 32ccf3acddde78924c79bae02115948a 109 Pfam PF00893 Small Multidrug Resistance protein 3 95 2.1E-21 T 28-03-2018 IPR000390 Small multidrug resistance protein family GO:0016021 CNX65_RS12440 8916e656d4a164a27a87cc7aac322ea4 99 Pfam PF07561 Domain of Unknown Function (DUF1540) 62 92 0.0047 T 28-03-2018 IPR011437 Domain of unknown function DUF1540 CNX65_RS12440 8916e656d4a164a27a87cc7aac322ea4 99 Pfam PF07561 Domain of Unknown Function (DUF1540) 11 43 9.0E-4 T 28-03-2018 IPR011437 Domain of unknown function DUF1540 CNX65_RS26380 0c53de2223e08605710d489993a44da9 248 Pfam PF14428 SCP1.201-like deaminase 120 242 5.9E-38 T 28-03-2018 IPR032724 Deaminase, SCP1.201-like CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 28-03-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 1.6E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 1.6E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 1.6E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 296 315 1.6E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 1.6E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 1.6E-56 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 SMART SM01004 2 322 3.6E-212 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 Gene3D G3DSA:3.20.20.70 1 324 1.0E-142 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 PIRSF PIRSF001415 1 324 3.7E-142 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 SUPERFAMILY SSF51569 2 323 1.42E-128 T 28-03-2018 CNX65_RS33150 0f437e00fc57b5eeddd2721794ef2746 324 Pfam PF00490 Delta-aminolevulinic acid dehydratase 5 321 6.0E-135 T 28-03-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 CNX65_RS34170 fd76577be45bede7d54fc91b35439d92 137 Pfam PF11349 Protein of unknown function (DUF3151) 9 132 1.6E-55 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CNX65_RS34170 fd76577be45bede7d54fc91b35439d92 137 PIRSF PIRSF017349 1 137 1.1E-55 T 28-03-2018 IPR014487 Protein of unknown function DUF3151 CNX65_RS04585 463a6ec9c4a3450aedfcbf2e4e1d72f9 436 Gene3D G3DSA:3.30.200.20 103 239 1.5E-25 T 28-03-2018 CNX65_RS04585 463a6ec9c4a3450aedfcbf2e4e1d72f9 436 Pfam PF03109 ABC1 family 112 227 8.1E-33 T 28-03-2018 IPR004147 UbiB domain CNX65_RS04585 463a6ec9c4a3450aedfcbf2e4e1d72f9 436 SUPERFAMILY SSF56112 95 158 6.81E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS04585 463a6ec9c4a3450aedfcbf2e4e1d72f9 436 SUPERFAMILY SSF56112 195 307 6.81E-28 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS04585 463a6ec9c4a3450aedfcbf2e4e1d72f9 436 Gene3D G3DSA:1.10.510.10 250 344 3.4E-5 T 28-03-2018 CNX65_RS07915 a737d285e877753f6341494059b6a06e 129 Pfam PF14078 Domain of unknown function (DUF4259) 2 115 7.7E-30 T 28-03-2018 IPR025355 Protein of unknown function DUF4259 CNX65_RS28020 e3244d58f065435b1080e301f3af6c9b 228 Gene3D G3DSA:3.40.50.970 13 224 6.1E-39 T 28-03-2018 CNX65_RS28020 e3244d58f065435b1080e301f3af6c9b 228 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 25 209 2.3E-27 T 28-03-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 CNX65_RS28020 e3244d58f065435b1080e301f3af6c9b 228 SUPERFAMILY SSF52518 28 223 4.1E-46 T 28-03-2018 IPR029061 Thiamin diphosphate-binding fold CNX65_RS25475 f15e28af70b81af58e0ad3be3c12732b 184 Pfam PF12804 MobA-like NTP transferase domain 5 162 1.1E-29 T 28-03-2018 IPR025877 MobA-like NTP transferase CNX65_RS25475 f15e28af70b81af58e0ad3be3c12732b 184 SUPERFAMILY SSF53448 3 181 1.91E-22 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS25475 f15e28af70b81af58e0ad3be3c12732b 184 Gene3D G3DSA:3.90.550.10 1 181 6.8E-23 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS09785 a2154ac64bc948385bf13cb2362b58a3 66 Gene3D G3DSA:3.30.70.20 2 65 8.9E-6 T 28-03-2018 CNX65_RS09785 a2154ac64bc948385bf13cb2362b58a3 66 SUPERFAMILY SSF54862 4 63 4.98E-12 T 28-03-2018 CNX65_RS09785 a2154ac64bc948385bf13cb2362b58a3 66 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 7.7E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS09785 a2154ac64bc948385bf13cb2362b58a3 66 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 7.7E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS09785 a2154ac64bc948385bf13cb2362b58a3 66 PRINTS PR00352 3Fe-4S ferredoxin signature 49 61 7.7E-5 T 28-03-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 CNX65_RS09785 a2154ac64bc948385bf13cb2362b58a3 66 Pfam PF06902 Divergent 4Fe-4S mono-cluster 4 64 8.4E-15 T 28-03-2018 IPR010693 Divergent 4Fe-4S mono-cluster CNX65_RS00625 726f0c238054e57dccebd2003475a2b4 355 Pfam PF00535 Glycosyl transferase family 2 14 176 9.0E-24 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS00625 726f0c238054e57dccebd2003475a2b4 355 SUPERFAMILY SSF53448 8 186 2.65E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS00625 726f0c238054e57dccebd2003475a2b4 355 Gene3D G3DSA:3.90.550.10 3 211 7.7E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS01445 55abdf573e8e3f177a307964662e01f7 136 Pfam PF07811 TadE-like protein 7 49 8.2E-6 T 28-03-2018 IPR012495 TadE-like CNX65_RS23030 129fd06c595d4dc8dcd6121d302da1a8 284 Gene3D G3DSA:2.60.120.380 40 237 3.3E-7 T 28-03-2018 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 Gene3D G3DSA:2.40.10.10 270 381 1.7E-16 T 28-03-2018 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 Gene3D G3DSA:2.40.10.10 176 269 3.1E-18 T 28-03-2018 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 PRINTS PR00834 HtrA/DegQ protease family signature 325 342 3.0E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 PRINTS PR00834 HtrA/DegQ protease family signature 245 265 3.0E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 PRINTS PR00834 HtrA/DegQ protease family signature 225 237 3.0E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 PRINTS PR00834 HtrA/DegQ protease family signature 284 308 3.0E-8 T 28-03-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 Pfam PF02674 Colicin V production protein 4 146 3.2E-14 T 28-03-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 Pfam PF13365 Trypsin-like peptidase domain 217 354 5.5E-23 T 28-03-2018 CNX65_RS01220 a21b4cdf379e87799f97b5d056b1a3fd 395 SUPERFAMILY SSF50494 191 375 1.19E-35 T 28-03-2018 IPR009003 Peptidase S1, PA clan CNX65_RS06840 767ebbdcd99319a9ba6ebd6bb3b0e7d2 376 SUPERFAMILY SSF53756 5 374 1.33E-78 T 28-03-2018 CNX65_RS06840 767ebbdcd99319a9ba6ebd6bb3b0e7d2 376 Pfam PF13439 Glycosyltransferase Family 4 16 172 1.6E-13 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS06840 767ebbdcd99319a9ba6ebd6bb3b0e7d2 376 Gene3D G3DSA:3.40.50.2000 19 181 3.2E-6 T 28-03-2018 CNX65_RS06840 767ebbdcd99319a9ba6ebd6bb3b0e7d2 376 Gene3D G3DSA:3.40.50.2000 182 359 6.1E-51 T 28-03-2018 CNX65_RS06840 767ebbdcd99319a9ba6ebd6bb3b0e7d2 376 Pfam PF00534 Glycosyl transferases group 1 185 356 1.5E-36 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS33590 c2bceb92d5f5823200e1c5ffcf2de3bf 140 Pfam PF02467 Transcription factor WhiB 61 130 1.9E-16 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS15790 ffd50879e59dfdb7cd4eaf7bd6176493 299 Pfam PF00296 Luciferase-like monooxygenase 12 255 5.6E-51 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS15790 ffd50879e59dfdb7cd4eaf7bd6176493 299 Gene3D G3DSA:3.20.20.30 6 296 9.8E-61 T 28-03-2018 CNX65_RS15790 ffd50879e59dfdb7cd4eaf7bd6176493 299 TIGRFAM TIGR03619 F420_Rv2161c: probable F420-dependent oxidoreductase, Rv2161c family 22 263 1.7E-59 T 28-03-2018 IPR019921 Luciferase-like, F420-dependent oxidoreductase, Rv2161c, predicted CNX65_RS15790 ffd50879e59dfdb7cd4eaf7bd6176493 299 SUPERFAMILY SSF51679 11 284 1.31E-56 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS03675 ea42bb46c7491497dce3697ccf46f965 398 Pfam PF09594 Glycosyltransferase family 87 71 300 6.8E-52 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CNX65_RS09575 279767b4fb1b6ca5016eff9d83a4b34e 328 Gene3D G3DSA:3.40.109.10 104 327 2.4E-27 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09575 279767b4fb1b6ca5016eff9d83a4b34e 328 SUPERFAMILY SSF55469 167 187 1.08E-8 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09575 279767b4fb1b6ca5016eff9d83a4b34e 328 SUPERFAMILY SSF55469 225 325 1.08E-8 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09575 279767b4fb1b6ca5016eff9d83a4b34e 328 SUPERFAMILY SSF55469 115 143 1.08E-8 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09575 279767b4fb1b6ca5016eff9d83a4b34e 328 SUPERFAMILY SSF55469 6 84 7.2E-10 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS09575 279767b4fb1b6ca5016eff9d83a4b34e 328 Gene3D G3DSA:3.40.109.30 2 97 4.5E-15 T 28-03-2018 CNX65_RS28860 0ad9a1aeb3f8ef5840cf2bf3f9baef6b 297 Pfam PF00892 EamA-like transporter family 8 130 1.0E-15 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS28860 0ad9a1aeb3f8ef5840cf2bf3f9baef6b 297 Pfam PF00892 EamA-like transporter family 142 278 6.9E-12 T 28-03-2018 IPR000620 EamA domain GO:0016020|GO:0016021 CNX65_RS28860 0ad9a1aeb3f8ef5840cf2bf3f9baef6b 297 SUPERFAMILY SSF103481 177 284 6.41E-8 T 28-03-2018 CNX65_RS28860 0ad9a1aeb3f8ef5840cf2bf3f9baef6b 297 SUPERFAMILY SSF103481 38 133 1.83E-10 T 28-03-2018 CNX65_RS01705 0d8e423bc693903b33a4afdc767d7a09 398 Pfam PF01032 FecCD transport family 78 391 1.3E-79 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS01705 0d8e423bc693903b33a4afdc767d7a09 398 SUPERFAMILY SSF81345 58 391 1.96E-66 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS01705 0d8e423bc693903b33a4afdc767d7a09 398 Gene3D G3DSA:1.10.3470.10 62 398 8.0E-66 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS09725 47b3a13757b36110cab288a44c55b6c7 237 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 113 166 1.2E-12 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CNX65_RS09725 47b3a13757b36110cab288a44c55b6c7 237 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 185 233 5.0E-8 T 28-03-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal CNX65_RS26850 2fa9632e28b97b9144e02b06105fea5f 243 Pfam PF13699 Domain of unknown function (DUF4157) 86 163 3.9E-33 T 28-03-2018 IPR025295 Domain of unknown function DUF4157 CNX65_RS26815 10988ca1f417a0e6efa3853fcda80854 251 SMART SM00257 196 243 5.9E-4 T 28-03-2018 IPR018392 LysM domain CNX65_RS26815 10988ca1f417a0e6efa3853fcda80854 251 Pfam PF01476 LysM domain 197 243 6.7E-8 T 28-03-2018 IPR018392 LysM domain CNX65_RS26815 10988ca1f417a0e6efa3853fcda80854 251 Gene3D G3DSA:3.10.350.10 191 248 1.1E-10 T 28-03-2018 CNX65_RS16010 1d13c5609415e14983258ae4de0b7c38 225 SUPERFAMILY SSF56037 50 213 8.37E-28 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CNX65_RS16010 1d13c5609415e14983258ae4de0b7c38 225 SMART SM00873 58 213 1.5E-13 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CNX65_RS16010 1d13c5609415e14983258ae4de0b7c38 225 Gene3D G3DSA:3.50.40.10 51 200 1.9E-21 T 28-03-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 CNX65_RS16010 1d13c5609415e14983258ae4de0b7c38 225 Pfam PF03483 B3/4 domain 60 191 9.0E-17 T 28-03-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 CNX65_RS13705 0401fe80bc9bd15088c35d2fbf304bc5 340 Gene3D G3DSA:1.10.3470.10 2 340 2.2E-71 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS13705 0401fe80bc9bd15088c35d2fbf304bc5 340 SUPERFAMILY SSF81345 4 335 1.57E-75 T 28-03-2018 IPR029022 ABC transporter, BtuC-like CNX65_RS13705 0401fe80bc9bd15088c35d2fbf304bc5 340 Pfam PF01032 FecCD transport family 18 335 5.1E-89 T 28-03-2018 IPR000522 ABC transporter, FecCD-like GO:0005215|GO:0016020 CNX65_RS00835 2acbf0cda5851ad87f0e3772df481994 207 SUPERFAMILY SSF159275 21 207 3.4E-43 T 28-03-2018 CNX65_RS00835 2acbf0cda5851ad87f0e3772df481994 207 Pfam PF06475 Putative glycolipid-binding 23 206 1.1E-46 T 28-03-2018 IPR009467 Putative glycolipid-binding protein CNX65_RS10075 9e114e36fbdef8b650af75f76857725f 141 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 26 122 3.9E-35 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 CNX65_RS33275 a04c6a9ae3878d04657c055eb2bf96d5 275 Gene3D G3DSA:3.20.20.100 2 275 2.7E-61 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS33275 a04c6a9ae3878d04657c055eb2bf96d5 275 SUPERFAMILY SSF51430 4 273 4.19E-59 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS33275 a04c6a9ae3878d04657c055eb2bf96d5 275 Pfam PF00248 Aldo/keto reductase family 9 272 4.3E-42 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS33275 a04c6a9ae3878d04657c055eb2bf96d5 275 PRINTS PR00069 Aldo-keto reductase signature 103 121 1.4E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS33275 a04c6a9ae3878d04657c055eb2bf96d5 275 PRINTS PR00069 Aldo-keto reductase signature 208 232 1.4E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS33275 a04c6a9ae3878d04657c055eb2bf96d5 275 PRINTS PR00069 Aldo-keto reductase signature 138 155 1.4E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS33275 a04c6a9ae3878d04657c055eb2bf96d5 275 PRINTS PR00069 Aldo-keto reductase signature 38 62 1.4E-9 T 28-03-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 CNX65_RS31175 f14a80ff47a9b22f3efea783606ba0bc 314 Gene3D G3DSA:1.10.340.30 102 269 1.1E-19 T 28-03-2018 CNX65_RS31175 f14a80ff47a9b22f3efea783606ba0bc 314 SUPERFAMILY SSF48150 116 295 8.72E-25 T 28-03-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 CNX65_RS32330 3c40468b17fafdc5e9d02eee8dbd78b1 183 Pfam PF08044 Domain of unknown function (DUF1707) 4 50 2.4E-9 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CNX65_RS07315 1e0100a4a9fcd6dabaa95c1b542a2dd4 384 SUPERFAMILY SSF103365 12 384 5.62E-132 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CNX65_RS07315 1e0100a4a9fcd6dabaa95c1b542a2dd4 384 Pfam PF01139 tRNA-splicing ligase RtcB 136 384 1.6E-97 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CNX65_RS07315 1e0100a4a9fcd6dabaa95c1b542a2dd4 384 Pfam PF01139 tRNA-splicing ligase RtcB 29 116 3.5E-29 T 28-03-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 CNX65_RS09560 55116203c4b8a8016b9a97b042ae925b 147 Pfam PF10706 Aminoglycoside-2''-adenylyltransferase 10 46 7.7E-6 T 28-03-2018 IPR019646 Aminoglycoside-2''-adenylyltransferase CNX65_RS09665 87cb357ebd3db4844fe46335775f4ea2 144 Pfam PF00582 Universal stress protein family 3 137 1.2E-28 T 28-03-2018 IPR006016 UspA GO:0006950 CNX65_RS09665 87cb357ebd3db4844fe46335775f4ea2 144 SUPERFAMILY SSF52402 3 139 1.0E-33 T 28-03-2018 CNX65_RS09665 87cb357ebd3db4844fe46335775f4ea2 144 Gene3D G3DSA:3.40.50.620 1 142 3.1E-35 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS09665 87cb357ebd3db4844fe46335775f4ea2 144 PRINTS PR01438 Universal stress protein signature 97 109 1.3E-17 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS09665 87cb357ebd3db4844fe46335775f4ea2 144 PRINTS PR01438 Universal stress protein signature 115 137 1.3E-17 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS09665 87cb357ebd3db4844fe46335775f4ea2 144 PRINTS PR01438 Universal stress protein signature 2 20 1.3E-17 T 28-03-2018 IPR006015 Universal stress protein A CNX65_RS27555 c46b4fa9bce1de8bb48ae3fd7157be28 173 Gene3D G3DSA:2.60.40.1240 38 161 6.7E-8 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CNX65_RS18770 717a4f4bbca6d7ab31dd09703bf3ce63 319 SUPERFAMILY SSF75005 16 318 6.28E-72 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS18770 717a4f4bbca6d7ab31dd09703bf3ce63 319 PIRSF PIRSF026534 2 319 4.1E-101 T 28-03-2018 IPR016840 Glycoside hydrolase, family 43, endo-1, 5-alpha-L-arabinosidase GO:0046558 CNX65_RS18770 717a4f4bbca6d7ab31dd09703bf3ce63 319 Gene3D G3DSA:2.115.10.20 22 319 6.0E-65 T 28-03-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain CNX65_RS18770 717a4f4bbca6d7ab31dd09703bf3ce63 319 Pfam PF04616 Glycosyl hydrolases family 43 40 316 4.5E-50 T 28-03-2018 IPR006710 Glycoside hydrolase, family 43 GO:0004553|GO:0005975 CNX65_RS06785 84126bea19a1183b855f3a3250181574 136 Gene3D G3DSA:3.40.50.2300 4 131 8.5E-10 T 28-03-2018 CNX65_RS06785 84126bea19a1183b855f3a3250181574 136 SUPERFAMILY SSF52172 7 129 1.38E-7 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS29135 3c1019397c121ab140ba726da39f59cf 492 Gene3D G3DSA:3.40.50.1820 4 461 6.0E-18 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29135 3c1019397c121ab140ba726da39f59cf 492 Pfam PF00561 alpha/beta hydrolase fold 30 226 1.7E-13 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS29135 3c1019397c121ab140ba726da39f59cf 492 SUPERFAMILY SSF53474 281 336 1.76E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29135 3c1019397c121ab140ba726da39f59cf 492 SUPERFAMILY SSF53474 10 75 1.76E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29135 3c1019397c121ab140ba726da39f59cf 492 SUPERFAMILY SSF53474 108 176 1.76E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29135 3c1019397c121ab140ba726da39f59cf 492 SUPERFAMILY SSF53474 388 445 1.76E-10 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS29135 3c1019397c121ab140ba726da39f59cf 492 Pfam PF08386 TAP-like protein 381 473 4.8E-11 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS30905 9818dc5a144db15dfdb9e8b4fe56a74e 121 Gene3D G3DSA:1.10.287.1060 1 97 5.6E-4 T 28-03-2018 CNX65_RS30905 9818dc5a144db15dfdb9e8b4fe56a74e 121 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 7 95 8.0E-6 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CNX65_RS32155 6f3b56b5eecc8844b184b2f8ab855f78 556 TIGRFAM TIGR04141 TIGR04141: sporadically distributed protein, TIGR04141 family 24 551 2.4E-108 T 28-03-2018 IPR026487 Sporadically distributed protein CHP04141 CNX65_RS31350 97bb6fe0998a0c615f7836d822209820 1314 Pfam PF14021 Tuberculosis necrotizing toxin 1227 1312 4.2E-26 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CNX65_RS31350 97bb6fe0998a0c615f7836d822209820 1314 Gene3D G3DSA:1.10.287.1060 21 117 7.6E-8 T 28-03-2018 CNX65_RS11960 bdcf0790dd63154ed2fea2f2953ec6b1 132 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 83 128 3.5E-6 T 28-03-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain CNX65_RS24145 ac2b8bd5f415b811b484ee8707a65954 258 Gene3D G3DSA:1.10.3720.10 10 256 1.8E-24 T 28-03-2018 CNX65_RS24145 ac2b8bd5f415b811b484ee8707a65954 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 254 2.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS24145 ac2b8bd5f415b811b484ee8707a65954 258 SUPERFAMILY SSF161098 58 240 6.02E-27 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS01555 52cd8376c0bae74302dd9c3c598ab308 257 Pfam PF05901 Excalibur calcium-binding domain 222 257 2.7E-13 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CNX65_RS01555 52cd8376c0bae74302dd9c3c598ab308 257 SUPERFAMILY SSF50199 61 164 1.2E-10 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CNX65_RS01555 52cd8376c0bae74302dd9c3c598ab308 257 Gene3D G3DSA:2.40.50.90 60 173 4.0E-6 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CNX65_RS01555 52cd8376c0bae74302dd9c3c598ab308 257 SMART SM00894 221 257 4.8E-19 T 28-03-2018 IPR008613 Excalibur calcium-binding domain CNX65_RS23090 7a91cbec5d0d73faf1107cbdd154efa0 241 Gene3D G3DSA:3.40.50.150 1 224 7.8E-33 T 28-03-2018 CNX65_RS23090 7a91cbec5d0d73faf1107cbdd154efa0 241 Pfam PF13649 Methyltransferase domain 42 137 1.0E-18 T 28-03-2018 CNX65_RS23090 7a91cbec5d0d73faf1107cbdd154efa0 241 SUPERFAMILY SSF53335 19 217 2.15E-37 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS33335 d8f6edb78f5ad7de93fb8ae2cb2f5271 251 SUPERFAMILY SSF53335 17 139 3.82E-7 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS33335 d8f6edb78f5ad7de93fb8ae2cb2f5271 251 Gene3D G3DSA:3.40.50.150 8 241 1.1E-9 T 28-03-2018 CNX65_RS30865 a5918eea6a4752f33bf21739b458d5df 243 SUPERFAMILY SSF161098 24 204 1.03E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS30865 a5918eea6a4752f33bf21739b458d5df 243 Gene3D G3DSA:1.10.3720.10 4 215 2.0E-26 T 28-03-2018 CNX65_RS30865 a5918eea6a4752f33bf21739b458d5df 243 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 215 1.8E-18 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12125 8718141c8293b7808b0d90cc78cec460 224 Pfam PF03591 AzlC protein 3 140 7.3E-30 T 28-03-2018 IPR011606 Branched-chain amino acid transport, permease CNX65_RS06940 139f9795a3c90421c0924de0108cc11e 146 Gene3D G3DSA:1.20.1290.10 1 144 2.4E-35 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS06940 139f9795a3c90421c0924de0108cc11e 146 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 27 75 1.1E-15 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS06940 139f9795a3c90421c0924de0108cc11e 146 Pfam PF02627 Carboxymuconolactone decarboxylase family 10 90 1.6E-16 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS06940 139f9795a3c90421c0924de0108cc11e 146 SUPERFAMILY SSF69118 8 141 1.15E-39 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS04535 f44566dd3709c2ccef28f9872ce3b695 157 PIRSF PIRSF021697 1 156 3.3E-45 T 28-03-2018 IPR016795 Uncharacterised conserved protein UCP021697, membrane CNX65_RS01810 21b7e1be0710b4ebabfde445ae8c785a 280 SUPERFAMILY SSF52540 12 240 1.81E-52 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS01810 21b7e1be0710b4ebabfde445ae8c785a 280 Pfam PF00005 ABC transporter 34 179 4.3E-24 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS01810 21b7e1be0710b4ebabfde445ae8c785a 280 SMART SM00382 42 229 7.5E-15 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS01810 21b7e1be0710b4ebabfde445ae8c785a 280 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS01810 21b7e1be0710b4ebabfde445ae8c785a 280 Gene3D G3DSA:3.40.50.300 1 253 1.1E-49 T 28-03-2018 CNX65_RS23795 5a372a3069a5df05a19e75f75be28fcd 294 SMART SM00849 58 267 1.8E-19 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS23795 5a372a3069a5df05a19e75f75be28fcd 294 SUPERFAMILY SSF56281 37 284 1.18E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS23795 5a372a3069a5df05a19e75f75be28fcd 294 Gene3D G3DSA:3.60.15.10 6 279 1.0E-46 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS23795 5a372a3069a5df05a19e75f75be28fcd 294 Pfam PF00753 Metallo-beta-lactamase superfamily 59 267 9.8E-24 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS16465 564e403e7f7a6ae3bbf2ba1fd79b94e1 180 Pfam PF02669 K+-transporting ATPase, c chain 10 177 1.3E-47 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CNX65_RS16465 564e403e7f7a6ae3bbf2ba1fd79b94e1 180 PIRSF PIRSF001296 4 180 4.6E-44 T 28-03-2018 IPR003820 Potassium-transporting ATPase C chain GO:0006813|GO:0008556|GO:0016021 CNX65_RS28190 98e74698f9c83704cf11d8b6be360db0 90 Gene3D G3DSA:3.30.1200.10 1 89 5.9E-28 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CNX65_RS28190 98e74698f9c83704cf11d8b6be360db0 90 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 3 73 3.5E-26 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CNX65_RS28190 98e74698f9c83704cf11d8b6be360db0 90 SMART SM01152 1 75 2.7E-28 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CNX65_RS28190 98e74698f9c83704cf11d8b6be360db0 90 Hamap MF_00634 UPF0235 protein YggU [yggU]. 1 86 16.585 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CNX65_RS28190 98e74698f9c83704cf11d8b6be360db0 90 SUPERFAMILY SSF69786 3 78 6.41E-23 T 28-03-2018 IPR003746 Protein of unknown function DUF167 CNX65_RS17765 a3f6f82cd3f0bd8f686179889a7a5bf4 181 Pfam PF08719 Domain of unknown function (DUF1768) 12 169 5.1E-48 T 28-03-2018 IPR012816 NADAR CNX65_RS17765 a3f6f82cd3f0bd8f686179889a7a5bf4 181 SUPERFAMILY SSF143990 8 171 9.29E-45 T 28-03-2018 CNX65_RS17765 a3f6f82cd3f0bd8f686179889a7a5bf4 181 TIGRFAM TIGR02464 ribofla_fusion: conserved hypothetical protein 10 169 6.4E-46 T 28-03-2018 IPR012816 NADAR CNX65_RS34445 1951c7b7bddb5417a1bbf4bad3bed0b7 122 Gene3D G3DSA:3.40.50.1010 15 120 4.0E-4 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS05590 d76114c489a22b54204fa39cda5c2185 275 PIRSF PIRSF006648 1 274 3.3E-62 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05590 d76114c489a22b54204fa39cda5c2185 275 Pfam PF01061 ABC-2 type transporter 23 238 2.6E-36 T 28-03-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 CNX65_RS05590 d76114c489a22b54204fa39cda5c2185 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 43 64 5.8E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05590 d76114c489a22b54204fa39cda5c2185 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 217 236 5.8E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS05590 d76114c489a22b54204fa39cda5c2185 275 PRINTS PR00164 ABC-2 type transport system membrane protein signature 197 216 5.8E-8 T 28-03-2018 IPR000412 ABC-2 transporter GO:0006810|GO:0016020 CNX65_RS09185 558b3eb9f86a4c1ec1e3dccb7c51ea23 320 Gene3D G3DSA:2.60.40.10 177 271 3.3E-4 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS09185 558b3eb9f86a4c1ec1e3dccb7c51ea23 320 Gene3D G3DSA:2.60.40.10 38 165 4.7E-8 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS30165 22a3da49d22f86bf657be7bfb84d33b9 121 Gene3D G3DSA:1.10.287.1060 1 121 6.5E-4 T 28-03-2018 CNX65_RS11310 b00ce7fbb6f28dd67eb6881dd58f5b5f 289 Gene3D G3DSA:3.90.320.10 2 210 2.0E-25 T 28-03-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal GO:0003677|GO:0004518 CNX65_RS11310 b00ce7fbb6f28dd67eb6881dd58f5b5f 289 Pfam PF12705 PD-(D/E)XK nuclease superfamily 16 262 1.1E-38 T 28-03-2018 CNX65_RS11310 b00ce7fbb6f28dd67eb6881dd58f5b5f 289 SUPERFAMILY SSF52980 36 196 1.55E-9 T 28-03-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 CNX65_RS09965 b571622e2b9d7ae00de87b5428d83f34 425 Pfam PF00202 Aminotransferase class-III 26 422 7.3E-91 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS09965 b571622e2b9d7ae00de87b5428d83f34 425 PIRSF PIRSF000521 183 425 7.9E-29 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS09965 b571622e2b9d7ae00de87b5428d83f34 425 PIRSF PIRSF000521 25 153 7.8E-8 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS09965 b571622e2b9d7ae00de87b5428d83f34 425 Gene3D G3DSA:3.40.640.10 50 308 1.2E-72 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS09965 b571622e2b9d7ae00de87b5428d83f34 425 SUPERFAMILY SSF53383 16 423 1.29E-108 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS09965 b571622e2b9d7ae00de87b5428d83f34 425 Gene3D G3DSA:3.90.1150.10 309 425 7.0E-32 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS31070 18a2d15437504f61006cc875c6c9a666 206 SUPERFAMILY SSF53271 66 196 1.1E-16 T 28-03-2018 IPR029057 Phosphoribosyltransferase-like CNX65_RS31070 18a2d15437504f61006cc875c6c9a666 206 Gene3D G3DSA:3.40.50.2020 45 203 7.2E-23 T 28-03-2018 CNX65_RS10220 ea08677ee8f3df8b27198e201a22a605 445 Pfam PF00589 Phage integrase family 241 419 1.1E-19 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS10220 ea08677ee8f3df8b27198e201a22a605 445 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 73 129 8.7E-9 T 28-03-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 CNX65_RS10220 ea08677ee8f3df8b27198e201a22a605 445 Gene3D G3DSA:1.10.150.130 66 238 3.2E-22 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS10220 ea08677ee8f3df8b27198e201a22a605 445 SUPERFAMILY SSF56349 73 131 6.77E-58 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS10220 ea08677ee8f3df8b27198e201a22a605 445 SUPERFAMILY SSF56349 191 430 6.77E-58 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS10220 ea08677ee8f3df8b27198e201a22a605 445 Gene3D G3DSA:1.10.443.10 239 431 2.4E-37 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS19910 84a300e71223a38a52099da2ef7a6cb3 97 Pfam PF17032 zinc-ribbon family 19 72 7.9E-8 T 28-03-2018 IPR031493 Zinc-ribbon 15 CNX65_RS25325 d9bc744e633a4a019a95e90a565021f2 126 SUPERFAMILY SSF55961 6 114 3.44E-8 T 28-03-2018 CNX65_RS25325 d9bc744e633a4a019a95e90a565021f2 126 Gene3D G3DSA:3.30.530.20 3 125 9.1E-9 T 28-03-2018 IPR023393 START-like domain CNX65_RS01935 590774ea763074a425aaa9805331270a 550 Gene3D G3DSA:3.40.50.410 39 261 1.0E-22 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01935 590774ea763074a425aaa9805331270a 550 Pfam PF00092 von Willebrand factor type A domain 52 208 7.4E-10 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01935 590774ea763074a425aaa9805331270a 550 SUPERFAMILY SSF53300 50 241 7.63E-18 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS01935 590774ea763074a425aaa9805331270a 550 SMART SM00327 50 254 6.6E-6 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 Pfam PF01551 Peptidase family M23 75 160 3.1E-14 T 28-03-2018 IPR016047 Peptidase M23 CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 SUPERFAMILY SSF51261 53 143 3.27E-12 T 28-03-2018 IPR011055 Duplicated hybrid motif CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 PRINTS PR01217 Proline rich extensin signature 64 85 2.3E-9 T 28-03-2018 CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 PRINTS PR01217 Proline rich extensin signature 1 13 2.3E-9 T 28-03-2018 CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 PRINTS PR01217 Proline rich extensin signature 37 49 2.3E-9 T 28-03-2018 CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 PRINTS PR01217 Proline rich extensin signature 15 31 2.3E-9 T 28-03-2018 CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 PRINTS PR01217 Proline rich extensin signature 122 139 2.3E-9 T 28-03-2018 CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 PRINTS PR01217 Proline rich extensin signature 186 211 2.3E-9 T 28-03-2018 CNX65_RS29010 8fda57e70ad9633d46f88d1fe2e91149 295 Gene3D G3DSA:2.70.70.10 41 180 6.4E-19 T 28-03-2018 CNX65_RS25370 29bcd9c83a8f914354420fb7e0304d00 243 Gene3D G3DSA:3.40.50.1820 1 243 7.2E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS25370 29bcd9c83a8f914354420fb7e0304d00 243 SUPERFAMILY SSF53474 124 242 8.85E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS25370 29bcd9c83a8f914354420fb7e0304d00 243 SUPERFAMILY SSF53474 21 86 8.85E-15 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS14890 1d06a80f1771e5f2c9530b6dfea9771d 155 SUPERFAMILY SSF160424 11 145 2.48E-20 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS27365 4621f688bbe20b9529c37c3db32f4ef9 136 SUPERFAMILY SSF54593 4 131 4.16E-25 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS27365 4621f688bbe20b9529c37c3db32f4ef9 136 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 5 130 4.2E-12 T 28-03-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain CNX65_RS27365 4621f688bbe20b9529c37c3db32f4ef9 136 ProSitePatterns PS00934 Glyoxalase I signature 1. 7 28 - T 28-03-2018 IPR018146 Glyoxalase I, conserved site GO:0004462|GO:0046872 KEGG: 00620+4.4.1.5|MetaCyc: PWY-5386|Reactome: R-HSA-70268 CNX65_RS27365 4621f688bbe20b9529c37c3db32f4ef9 136 Gene3D G3DSA:3.10.180.10 2 135 3.8E-26 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS28590 408092cf5497819ff337ca77723cfcac 439 Pfam PF07690 Major Facilitator Superfamily 20 305 4.5E-28 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS28590 408092cf5497819ff337ca77723cfcac 439 Gene3D G3DSA:1.20.1250.20 4 202 6.9E-29 T 28-03-2018 CNX65_RS28590 408092cf5497819ff337ca77723cfcac 439 SUPERFAMILY SSF103473 5 411 4.97E-51 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS28590 408092cf5497819ff337ca77723cfcac 439 Gene3D G3DSA:1.20.1250.20 206 423 3.2E-10 T 28-03-2018 CNX65_RS27910 e98cacdc3968bad2bc9dc4cec5634fd4 303 Gene3D G3DSA:3.40.190.10 145 302 4.8E-29 T 28-03-2018 CNX65_RS27910 e98cacdc3968bad2bc9dc4cec5634fd4 303 Pfam PF16868 NMT1-like family 27 301 4.2E-47 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS27910 e98cacdc3968bad2bc9dc4cec5634fd4 303 Gene3D G3DSA:3.40.190.10 20 143 9.4E-11 T 28-03-2018 CNX65_RS27910 e98cacdc3968bad2bc9dc4cec5634fd4 303 SUPERFAMILY SSF53850 22 301 2.63E-53 T 28-03-2018 CNX65_RS27910 e98cacdc3968bad2bc9dc4cec5634fd4 303 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 6 302 2.3E-56 T 28-03-2018 IPR011852 TRAP transporter solute receptor, TAXI family CNX65_RS25340 aae1d1d08db784a4433dfc6b1d81decc 318 TIGRFAM TIGR03557 F420_G6P_family: F420-dependent oxidoreductase, G6PDH family 3 317 5.1E-150 T 28-03-2018 IPR019945 F420-dependent glucose-6-phosphate dehydrogenase-related CNX65_RS25340 aae1d1d08db784a4433dfc6b1d81decc 318 Pfam PF00296 Luciferase-like monooxygenase 1 290 2.8E-48 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS25340 aae1d1d08db784a4433dfc6b1d81decc 318 SUPERFAMILY SSF51679 1 317 4.42E-61 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS25340 aae1d1d08db784a4433dfc6b1d81decc 318 Gene3D G3DSA:3.20.20.30 5 318 1.8E-56 T 28-03-2018 CNX65_RS07075 60a440691b3f46215c89608b062c13e1 284 SUPERFAMILY SSF101478 9 263 6.41E-47 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS07075 60a440691b3f46215c89608b062c13e1 284 Pfam PF03747 ADP-ribosylglycohydrolase 34 252 1.4E-40 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS07075 60a440691b3f46215c89608b062c13e1 284 Gene3D G3DSA:1.10.4080.10 5 277 2.0E-53 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS33965 ff245c90bd35bf6e0ac952aeab1f563b 357 Gene3D G3DSA:2.160.20.80 162 343 2.0E-19 T 28-03-2018 CNX65_RS33965 ff245c90bd35bf6e0ac952aeab1f563b 357 Pfam PF13576 Pentapeptide repeats (9 copies) 278 320 3.2E-11 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS17535 a6e3acb1fdb9954e1290db947f997446 161 Gene3D G3DSA:1.10.1660.10 66 141 1.4E-14 T 28-03-2018 CNX65_RS17535 a6e3acb1fdb9954e1290db947f997446 161 Pfam PF13411 MerR HTH family regulatory protein 11 77 1.5E-16 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17535 a6e3acb1fdb9954e1290db947f997446 161 ProSitePatterns PS00552 MerR-type HTH domain signature. 13 35 - T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17535 a6e3acb1fdb9954e1290db947f997446 161 SMART SM00422 10 80 3.3E-15 T 28-03-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 CNX65_RS17535 a6e3acb1fdb9954e1290db947f997446 161 SUPERFAMILY SSF46955 10 126 5.19E-27 T 28-03-2018 IPR009061 Putative DNA-binding domain CNX65_RS17535 a6e3acb1fdb9954e1290db947f997446 161 Gene3D G3DSA:1.10.1660.10 6 65 7.2E-19 T 28-03-2018 CNX65_RS06950 57b902cc1a2632322d88b1dbbada011c 559 Pfam PF05960 Bacterial protein of unknown function (DUF885) 24 556 2.7E-162 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CNX65_RS20865 2df4c5d94705ae9ac217a10ccae8c61d 312 Pfam PF06675 Protein of unknown function (DUF1177) 39 309 1.3E-131 T 28-03-2018 IPR009561 Protein of unknown function DUF1177 CNX65_RS08400 49bd5cbd14799873a603d9a3c4b6ece8 556 PRINTS PR01217 Proline rich extensin signature 277 298 2.6E-9 T 28-03-2018 CNX65_RS08400 49bd5cbd14799873a603d9a3c4b6ece8 556 PRINTS PR01217 Proline rich extensin signature 325 342 2.6E-9 T 28-03-2018 CNX65_RS08400 49bd5cbd14799873a603d9a3c4b6ece8 556 PRINTS PR01217 Proline rich extensin signature 298 314 2.6E-9 T 28-03-2018 CNX65_RS08400 49bd5cbd14799873a603d9a3c4b6ece8 556 PRINTS PR01217 Proline rich extensin signature 362 387 2.6E-9 T 28-03-2018 CNX65_RS20420 228c3670c5b6a97b238eb607681f3cbd 191 SUPERFAMILY SSF69118 13 165 8.64E-37 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS20420 228c3670c5b6a97b238eb607681f3cbd 191 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 43 75 2.8E-8 T 28-03-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS20420 228c3670c5b6a97b238eb607681f3cbd 191 Pfam PF02627 Carboxymuconolactone decarboxylase family 32 107 7.7E-6 T 28-03-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 CNX65_RS20420 228c3670c5b6a97b238eb607681f3cbd 191 Gene3D G3DSA:1.20.1290.10 6 171 1.2E-28 T 28-03-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 CNX65_RS20535 8f289aba7447026bf3f2db8f9e157274 328 Pfam PF08012 Protein of unknown function (DUF1702) 5 322 2.7E-133 T 28-03-2018 IPR012964 Protein of unknown function DUF1702 CNX65_RS16450 729092044d01852824b7bd12b9f3822d 346 Pfam PF00248 Aldo/keto reductase family 20 317 2.0E-73 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS16450 729092044d01852824b7bd12b9f3822d 346 Gene3D G3DSA:3.20.20.100 8 322 3.6E-91 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS16450 729092044d01852824b7bd12b9f3822d 346 SUPERFAMILY SSF51430 8 318 4.85E-96 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS33040 ce4fa7bbb9fcac42d8cead4efa069a8d 292 Pfam PF13560 Helix-turn-helix domain 11 71 7.9E-10 T 28-03-2018 CNX65_RS33040 ce4fa7bbb9fcac42d8cead4efa069a8d 292 Gene3D G3DSA:1.10.260.40 1 89 1.3E-11 T 28-03-2018 CNX65_RS33040 ce4fa7bbb9fcac42d8cead4efa069a8d 292 SUPERFAMILY SSF47413 6 70 6.76E-10 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS33040 ce4fa7bbb9fcac42d8cead4efa069a8d 292 SMART SM00530 15 70 9.0E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS29195 37597e7c05c7b15b7a02d242ae94f5f7 509 Pfam PF00474 Sodium:solute symporter family 33 389 3.7E-24 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS08340 abca29760cdcefc2617c241265293b6f 292 TIGRFAM TIGR03409 urea_trans_UrtB: urea ABC transporter, permease protein UrtB 6 289 8.1E-114 T 28-03-2018 IPR017779 ABC transporter, urea permease protein UrtB, bacterial-type CNX65_RS08340 abca29760cdcefc2617c241265293b6f 292 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 276 6.4E-47 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS08340 abca29760cdcefc2617c241265293b6f 292 Gene3D G3DSA:1.10.3470.10 1 287 7.8E-47 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS16495 3e62c5c2741cd039123e10b57886beb4 144 Gene3D G3DSA:3.30.565.10 19 144 1.7E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16495 3e62c5c2741cd039123e10b57886beb4 144 Pfam PF13581 Histidine kinase-like ATPase domain 30 135 1.4E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16495 3e62c5c2741cd039123e10b57886beb4 144 SUPERFAMILY SSF55874 49 139 1.23E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS23095 d1a6fb217b0b9a1b92e22768f89a882f 109 Gene3D G3DSA:3.30.70.100 1 97 6.2E-24 T 28-03-2018 CNX65_RS23095 d1a6fb217b0b9a1b92e22768f89a882f 109 SUPERFAMILY SSF54909 1 95 2.73E-21 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS23095 d1a6fb217b0b9a1b92e22768f89a882f 109 Pfam PF07045 Domain of unknown function (DUF1330) 2 95 1.4E-24 T 28-03-2018 IPR010753 Domain of unknown function DUF1330 CNX65_RS18950 d84ee41b79975e39c9c013b29c819e95 285 SUPERFAMILY SSF101898 58 274 9.68E-32 T 28-03-2018 CNX65_RS18950 d84ee41b79975e39c9c013b29c819e95 285 SUPERFAMILY SSF63825 4 84 2.25E-8 T 28-03-2018 CNX65_RS18950 d84ee41b79975e39c9c013b29c819e95 285 Gene3D G3DSA:2.120.10.30 130 260 2.1E-17 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS18950 d84ee41b79975e39c9c013b29c819e95 285 Gene3D G3DSA:2.120.10.30 261 285 0.22 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS18950 d84ee41b79975e39c9c013b29c819e95 285 Gene3D G3DSA:2.120.10.30 2 129 1.8E-10 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS13145 de7c5b4c4f37b71b63a774f96cfadabc 204 ProDom PD338207 MEMBRANE INTEGRAL TRANSMEMBRANE PLASMID PROBABLE MB0995 RV0970/MT0998 7 64 0.008 T 28-03-2018 CNX65_RS13145 de7c5b4c4f37b71b63a774f96cfadabc 204 Pfam PF17197 Domain of unknown function (DUF5134) 34 203 5.1E-34 T 28-03-2018 IPR033458 Protein of unknown function DUF5134 CNX65_RS29715 6b0a55209ffbb649e6a693fb8a935b37 270 Pfam PF03601 Conserved hypothetical protein 698 21 250 1.3E-48 T 28-03-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 CNX65_RS15375 520bf088bdb389e1bd4479aa45630e8d 701 Gene3D G3DSA:3.40.50.300 200 530 1.8E-25 T 28-03-2018 CNX65_RS15375 520bf088bdb389e1bd4479aa45630e8d 701 SUPERFAMILY SSF52540 194 368 1.25E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15375 520bf088bdb389e1bd4479aa45630e8d 701 SUPERFAMILY SSF52540 458 690 1.25E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15375 520bf088bdb389e1bd4479aa45630e8d 701 Gene3D G3DSA:3.40.50.300 537 699 3.3E-15 T 28-03-2018 CNX65_RS15375 520bf088bdb389e1bd4479aa45630e8d 701 Pfam PF13245 AAA domain 213 513 1.8E-6 T 28-03-2018 CNX65_RS02235 427c79dd63bf35af250711df84d77eae 448 SMART SM00220 13 267 2.8E-50 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS02235 427c79dd63bf35af250711df84d77eae 448 SUPERFAMILY SSF56112 9 273 1.32E-64 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS02235 427c79dd63bf35af250711df84d77eae 448 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 19 42 - T 28-03-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 CNX65_RS02235 427c79dd63bf35af250711df84d77eae 448 Pfam PF00069 Protein kinase domain 13 261 2.6E-41 T 28-03-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 CNX65_RS02235 427c79dd63bf35af250711df84d77eae 448 Gene3D G3DSA:3.30.200.20 2 109 1.4E-22 T 28-03-2018 CNX65_RS02235 427c79dd63bf35af250711df84d77eae 448 Gene3D G3DSA:1.10.510.10 110 313 3.5E-37 T 28-03-2018 CNX65_RS02235 427c79dd63bf35af250711df84d77eae 448 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 131 143 - T 28-03-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 CNX65_RS23085 3e2466714a7b028f79c22edb48828520 233 TIGRFAM TIGR04539 tRNA_cyclodipep: tRNA-dependent cyclodipeptide synthase 13 231 1.4E-75 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CNX65_RS23085 3e2466714a7b028f79c22edb48828520 233 Pfam PF16715 Cyclodipeptide synthase 13 231 8.2E-73 T 28-03-2018 IPR030903 Cyclodileucine synthase GO:0016755 CNX65_RS29910 a602140e5c3b66e33bd390fc34c6ea32 482 Pfam PF04228 Putative neutral zinc metallopeptidase 69 266 1.7E-8 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CNX65_RS29910 a602140e5c3b66e33bd390fc34c6ea32 482 SUPERFAMILY SSF55486 65 209 4.67E-10 T 28-03-2018 CNX65_RS26820 5075f3cbfbbdd7e0a7756797e9e56193 143 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 7 139 6.3E-28 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 CNX65_RS26820 5075f3cbfbbdd7e0a7756797e9e56193 143 Pfam PF06841 T4-like virus tail tube protein gp19 10 138 3.6E-31 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 CNX65_RS32895 e84d038172940556d4b5f3e8afa477c3 447 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 221 234 - T 28-03-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32895 e84d038172940556d4b5f3e8afa477c3 447 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 11 343 24.661 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32895 e84d038172940556d4b5f3e8afa477c3 447 Pfam PF00146 NADH dehydrogenase 18 336 6.7E-127 T 28-03-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS29780 1cd4fdb7f1075900aa963030153e181a 259 SUPERFAMILY SSF52402 1 253 9.42E-76 T 28-03-2018 CNX65_RS29780 1cd4fdb7f1075900aa963030153e181a 259 SMART SM00893 23 212 2.6E-54 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CNX65_RS29780 1cd4fdb7f1075900aa963030153e181a 259 Pfam PF01012 Electron transfer flavoprotein domain 25 208 3.4E-49 T 28-03-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 CNX65_RS29780 1cd4fdb7f1075900aa963030153e181a 259 PIRSF PIRSF000090 1 259 1.3E-86 T 28-03-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 CNX65_RS29780 1cd4fdb7f1075900aa963030153e181a 259 Gene3D G3DSA:3.40.50.620 1 259 1.2E-75 T 28-03-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold CNX65_RS26970 9b567e82583634fbcbcc253766f6d397 140 Pfam PF03259 Roadblock/LC7 domain 13 102 2.6E-24 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS26970 9b567e82583634fbcbcc253766f6d397 140 Gene3D G3DSA:3.30.450.30 7 134 6.2E-43 T 28-03-2018 CNX65_RS26970 9b567e82583634fbcbcc253766f6d397 140 SUPERFAMILY SSF103196 5 129 8.89E-34 T 28-03-2018 CNX65_RS26970 9b567e82583634fbcbcc253766f6d397 140 SMART SM00960 12 102 1.0E-32 T 28-03-2018 IPR004942 Roadblock/LAMTOR2 domain CNX65_RS11685 6ea7da7342ce5588ef95682cd0e4cfcf 134 Gene3D G3DSA:3.30.565.10 7 134 4.5E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS11685 6ea7da7342ce5588ef95682cd0e4cfcf 134 SUPERFAMILY SSF55874 38 113 3.66E-5 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS15165 b68ae0528c84721efeb5c78d6b04a1d2 128 SUPERFAMILY SSF54427 4 103 1.46E-22 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS15165 b68ae0528c84721efeb5c78d6b04a1d2 128 Gene3D G3DSA:3.10.450.50 1 128 1.0E-23 T 28-03-2018 CNX65_RS15165 b68ae0528c84721efeb5c78d6b04a1d2 128 Pfam PF12680 SnoaL-like domain 4 96 7.0E-11 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS12680 5f50f1cc6bbbd31df1b3e2e54145674f 162 SMART SM00754 41 160 5.4E-9 T 28-03-2018 IPR010895 CHRD CNX65_RS12680 5f50f1cc6bbbd31df1b3e2e54145674f 162 Pfam PF07452 CHRD domain 45 158 3.2E-16 T 28-03-2018 IPR010895 CHRD CNX65_RS20675 8f8b6d5fa0669a5f0a91854f6d345701 642 Gene3D G3DSA:3.40.50.880 350 581 5.8E-16 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS20675 8f8b6d5fa0669a5f0a91854f6d345701 642 SUPERFAMILY SSF51445 8 336 3.68E-46 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS20675 8f8b6d5fa0669a5f0a91854f6d345701 642 Gene3D G3DSA:3.20.20.80 1 335 1.0E-39 T 28-03-2018 CNX65_RS20675 8f8b6d5fa0669a5f0a91854f6d345701 642 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 48 296 7.8E-9 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS22880 e5d9a8fa624c8f821ae8d8802915f1a2 301 Gene3D G3DSA:2.60.120.620 3 271 5.0E-38 T 28-03-2018 CNX65_RS22880 e5d9a8fa624c8f821ae8d8802915f1a2 301 Pfam PF05721 Phytanoyl-CoA dioxygenase (PhyH) 25 247 2.0E-21 T 28-03-2018 IPR008775 Phytanoyl-CoA dioxygenase CNX65_RS22880 e5d9a8fa624c8f821ae8d8802915f1a2 301 SUPERFAMILY SSF51197 15 261 2.47E-45 T 28-03-2018 CNX65_RS25935 b922230957536c2f9f119eb5f41022e6 216 Pfam PF13280 WYL domain 41 209 5.6E-23 T 28-03-2018 IPR026881 WYL domain CNX65_RS21260 a2b59a29756b2b2d93558e2ab5c8d2f1 329 Pfam PF00248 Aldo/keto reductase family 14 306 9.2E-62 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS21260 a2b59a29756b2b2d93558e2ab5c8d2f1 329 SUPERFAMILY SSF51430 12 307 6.81E-82 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS21260 a2b59a29756b2b2d93558e2ab5c8d2f1 329 Gene3D G3DSA:3.20.20.100 1 326 1.1E-86 T 28-03-2018 IPR023210 NADP-dependent oxidoreductase domain CNX65_RS32510 566712abb17e4d10b521fd780b845379 97 Pfam PF13453 Transcription factor zinc-finger 2 40 4.4E-17 T 28-03-2018 IPR027392 Transcription factor zinc-finger CNX65_RS28315 3eb9340d3208ceec7642fe0fa2471ba5 128 Pfam PF11239 Protein of unknown function (DUF3040) 1 84 6.4E-30 T 28-03-2018 IPR021401 Protein of unknown function DUF3040 CNX65_RS33395 4890758e82e4179ebaa24fa66f6bfe7c 375 Gene3D G3DSA:3.40.50.150 11 282 4.2E-34 T 28-03-2018 CNX65_RS33395 4890758e82e4179ebaa24fa66f6bfe7c 375 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 97 215 3.3E-25 T 28-03-2018 CNX65_RS33395 4890758e82e4179ebaa24fa66f6bfe7c 375 SUPERFAMILY SSF53335 81 213 1.8E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS33395 4890758e82e4179ebaa24fa66f6bfe7c 375 SUPERFAMILY SSF53335 8 43 1.8E-25 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS02765 bbf7831fdfb72cf128b2dc8455025f19 86 Gene3D G3DSA:1.20.120.570 1 86 7.5E-5 T 28-03-2018 CNX65_RS29695 5c1c353a07dabf688670ae39a7b22059 162 Pfam PF04434 SWIM zinc finger 59 81 2.6E-4 T 28-03-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 CNX65_RS06945 da114a848eb769f1cb9d46ef7c0869cf 217 Pfam PF11353 Protein of unknown function (DUF3153) 60 205 3.2E-8 T 28-03-2018 IPR021499 Protein of unknown function DUF3153 CNX65_RS29065 d0796c625912a7bc70d66074c2778a85 246 Gene3D G3DSA:3.40.1280.10 1 171 6.9E-75 T 28-03-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal CNX65_RS29065 d0796c625912a7bc70d66074c2778a85 246 Gene3D G3DSA:1.10.1270.20 172 246 2.4E-30 T 28-03-2018 CNX65_RS29065 d0796c625912a7bc70d66074c2778a85 246 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 229 3.3E-76 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CNX65_RS29065 d0796c625912a7bc70d66074c2778a85 246 PIRSF PIRSF000386 1 242 9.3E-94 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CNX65_RS29065 d0796c625912a7bc70d66074c2778a85 246 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 246 103.579 T 28-03-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CNX65_RS29065 d0796c625912a7bc70d66074c2778a85 246 SUPERFAMILY SSF75217 1 232 4.19E-90 T 28-03-2018 IPR029028 Alpha/beta knot methyltransferases CNX65_RS29065 d0796c625912a7bc70d66074c2778a85 246 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 22 223 1.6E-67 T 28-03-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain KEGG: 00340+2.1.1.22|MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 CNX65_RS21125 e89ba8e69901d57cc4c929dd30038a10 192 SUPERFAMILY SSF82607 17 103 1.24E-6 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS21125 e89ba8e69901d57cc4c929dd30038a10 192 Gene3D G3DSA:3.30.1310.10 7 106 1.6E-18 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS21125 e89ba8e69901d57cc4c929dd30038a10 192 Pfam PF02575 YbaB/EbfC DNA-binding family 17 103 1.0E-9 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS07885 f17243dea7a3cce12af869618243e86e 133 Pfam PF11236 Protein of unknown function (DUF3037) 7 124 7.1E-42 T 28-03-2018 IPR021398 Protein of unknown function DUF3037 CNX65_RS31290 daf2b3f1847d96a5d9c05b7e042d9001 474 Gene3D G3DSA:1.25.40.10 10 442 4.9E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS31290 daf2b3f1847d96a5d9c05b7e042d9001 474 SUPERFAMILY SSF48452 61 98 1.93E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS31290 daf2b3f1847d96a5d9c05b7e042d9001 474 SUPERFAMILY SSF48452 140 187 1.93E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS31290 daf2b3f1847d96a5d9c05b7e042d9001 474 SUPERFAMILY SSF48452 387 422 1.93E-8 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS03035 9920ecf508179add67a98a7ff6b4c844 378 Gene3D G3DSA:3.40.630.30 133 265 2.5E-14 T 28-03-2018 CNX65_RS03035 9920ecf508179add67a98a7ff6b4c844 378 Gene3D G3DSA:3.30.1050.10 266 372 2.7E-20 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS03035 9920ecf508179add67a98a7ff6b4c844 378 Pfam PF13530 Sterol carrier protein domain 167 366 1.5E-27 T 28-03-2018 IPR025559 Enhanced intracellular survival protein domain CNX65_RS03035 9920ecf508179add67a98a7ff6b4c844 378 Pfam PF13527 Acetyltransferase (GNAT) domain 3 120 1.9E-23 T 28-03-2018 CNX65_RS03035 9920ecf508179add67a98a7ff6b4c844 378 SUPERFAMILY SSF55729 3 272 1.11E-45 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS03035 9920ecf508179add67a98a7ff6b4c844 378 SUPERFAMILY SSF55718 273 378 4.32E-15 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS03035 9920ecf508179add67a98a7ff6b4c844 378 Gene3D G3DSA:3.40.630.30 1 132 8.3E-20 T 28-03-2018 CNX65_RS19970 0c33f042f456f4d1a27bb5b2859aeab9 410 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 132 149 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19970 0c33f042f456f4d1a27bb5b2859aeab9 410 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 267 283 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19970 0c33f042f456f4d1a27bb5b2859aeab9 410 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 205 216 1.4E-11 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19970 0c33f042f456f4d1a27bb5b2859aeab9 410 SUPERFAMILY SSF51735 126 301 2.12E-28 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS19970 0c33f042f456f4d1a27bb5b2859aeab9 410 Pfam PF00106 short chain dehydrogenase 131 287 1.2E-19 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19970 0c33f042f456f4d1a27bb5b2859aeab9 410 Gene3D G3DSA:3.40.50.720 117 284 1.3E-26 T 28-03-2018 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 226 239 - T 28-03-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 SUPERFAMILY SSF53383 8 381 1.24E-99 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 Gene3D G3DSA:3.90.1150.10 269 383 4.6E-29 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 Pfam PF00155 Aminotransferase class I and II 31 376 4.7E-58 T 28-03-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 Gene3D G3DSA:3.40.640.10 69 268 2.4E-48 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 158 182 4.4E-11 T 28-03-2018 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 4.4E-11 T 28-03-2018 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 4.4E-11 T 28-03-2018 CNX65_RS34085 d74268f00f09300b593f5094c33ac7e6 388 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 194 217 4.4E-11 T 28-03-2018 CNX65_RS07505 b925069fcfc145d1cb7b1e13e1f8311b 155 Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 4 146 31.678 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CNX65_RS07505 b925069fcfc145d1cb7b1e13e1f8311b 155 TIGRFAM TIGR00576 dut: dUTP diphosphatase 7 145 1.6E-50 T 28-03-2018 IPR008181 Deoxyuridine triphosphate nucleotidohydrolase GO:0004170|GO:0046080 KEGG: 00240+3.6.1.23|Reactome: R-HSA-499943 CNX65_RS07505 b925069fcfc145d1cb7b1e13e1f8311b 155 Pfam PF00692 dUTPase 18 145 3.8E-32 T 28-03-2018 IPR029054 dUTPase-like CNX65_RS07505 b925069fcfc145d1cb7b1e13e1f8311b 155 SUPERFAMILY SSF51283 4 145 1.83E-48 T 28-03-2018 IPR029054 dUTPase-like CNX65_RS07505 b925069fcfc145d1cb7b1e13e1f8311b 155 Gene3D G3DSA:2.70.40.10 2 109 3.4E-42 T 28-03-2018 CNX65_RS07505 b925069fcfc145d1cb7b1e13e1f8311b 155 Gene3D G3DSA:2.70.40.10 110 145 1.2E-13 T 28-03-2018 CNX65_RS31205 94b064943880580941a983076f96c4c5 300 Pfam PF00535 Glycosyl transferase family 2 1 152 4.0E-17 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS31205 94b064943880580941a983076f96c4c5 300 SUPERFAMILY SSF53448 1 222 8.44E-40 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS31205 94b064943880580941a983076f96c4c5 300 Gene3D G3DSA:3.90.550.10 1 234 1.7E-36 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS16440 f3cb3535000ab791ef1f8b17c98ebaae 378 Pfam PF09594 Glycosyltransferase family 87 70 288 1.9E-55 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CNX65_RS24270 27834ab542c9fb80867c76429cc07e31 658 Gene3D G3DSA:3.40.50.1820 342 639 2.6E-4 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24270 27834ab542c9fb80867c76429cc07e31 658 SUPERFAMILY SSF53474 449 557 3.83E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS24270 27834ab542c9fb80867c76429cc07e31 658 SUPERFAMILY SSF53474 341 404 3.83E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21420 b822261a6b6492e7319e155995600688 390 SUPERFAMILY SSF51395 19 377 5.27E-96 T 28-03-2018 CNX65_RS21420 b822261a6b6492e7319e155995600688 390 Gene3D G3DSA:3.20.20.70 7 389 1.8E-102 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS21420 b822261a6b6492e7319e155995600688 390 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 22 312 9.2E-55 T 28-03-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 CNX65_RS33295 1e21e5a44f279f884438a41b6784f9a2 349 Pfam PF14257 Domain of unknown function (DUF4349) 38 291 2.5E-66 T 28-03-2018 IPR025645 Domain of unknown function DUF4349 CNX65_RS33295 1e21e5a44f279f884438a41b6784f9a2 349 Gene3D G3DSA:1.10.287.620 152 274 1.2E-6 T 28-03-2018 CNX65_RS34590 220aa8612f92c8702b18e69a5d98ea6f 308 SUPERFAMILY SSF53067 4 302 3.08E-64 T 28-03-2018 CNX65_RS34590 220aa8612f92c8702b18e69a5d98ea6f 308 Gene3D G3DSA:3.30.420.40 119 304 2.3E-51 T 28-03-2018 CNX65_RS34590 220aa8612f92c8702b18e69a5d98ea6f 308 Pfam PF00480 ROK family 6 299 6.1E-60 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS34590 220aa8612f92c8702b18e69a5d98ea6f 308 Gene3D G3DSA:3.30.420.40 1 118 1.2E-30 T 28-03-2018 CNX65_RS34590 220aa8612f92c8702b18e69a5d98ea6f 308 ProSitePatterns PS01125 ROK family signature. 133 160 - T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS09870 1a73c96a002a27bc6017e02898ebd7bc 228 Pfam PF04854 Protein of unknown function, DUF624 37 115 8.9E-7 T 28-03-2018 IPR006938 Protein of unknown function DUF624 CNX65_RS19850 6507d7e3caf596d5f7da2a3b846f4ea5 367 Pfam PF14388 Domain of unknown function (DUF4419) 46 339 2.9E-59 T 28-03-2018 IPR025533 Protein of unknown function DUF4419 CNX65_RS10705 265055fbd2b8d483b8c8f343e1208b3d 500 Pfam PF02133 Permease for cytosine/purines, uracil, thiamine, allantoin 37 482 1.9E-129 T 28-03-2018 IPR001248 Purine-cytosine permease GO:0005215|GO:0016020|GO:0055085 CNX65_RS10705 265055fbd2b8d483b8c8f343e1208b3d 500 TIGRFAM TIGR00800 ncs1: NCS1 nucleoside transporter family 32 454 1.2E-119 T 28-03-2018 IPR012681 Nucleobase cation symporter-1, NCS1 GO:0005215|GO:0006810|GO:0016020 CNX65_RS13370 6607e5e713c10a8436a857ac4d057190 262 Pfam PF00941 FAD binding domain in molybdopterin dehydrogenase 33 164 3.5E-14 T 28-03-2018 IPR002346 Molybdopterin dehydrogenase, FAD-binding GO:0016491|GO:0055114 CNX65_RS13370 6607e5e713c10a8436a857ac4d057190 262 Gene3D G3DSA:3.30.465.10 53 165 4.9E-20 T 28-03-2018 IPR016169 CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2 GO:0050660 CNX65_RS13370 6607e5e713c10a8436a857ac4d057190 262 SUPERFAMILY SSF56176 17 164 3.6E-21 T 28-03-2018 IPR016166 FAD-binding, type 2 GO:0003824|GO:0016614|GO:0050660|GO:0055114 CNX65_RS04495 6e3c0358ffbcd094d2b503a32d916006 247 SUPERFAMILY SSF52317 27 189 1.48E-36 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS04495 6e3c0358ffbcd094d2b503a32d916006 247 Gene3D G3DSA:3.40.50.880 1 231 3.6E-37 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS04495 6e3c0358ffbcd094d2b503a32d916006 247 Pfam PF00117 Glutamine amidotransferase class-I 42 182 2.2E-14 T 28-03-2018 IPR017926 Glutamine amidotransferase CNX65_RS07920 139b44776cba761ec7a462f1f21257b7 261 Pfam PF07070 SpoOM protein 3 218 7.0E-81 T 28-03-2018 IPR009776 Sporulation stage 0, protein M CNX65_RS20815 c14946f05113fd9ed96607c57d01633e 275 Gene3D G3DSA:1.10.580.10 1 64 2.0E-8 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CNX65_RS20815 c14946f05113fd9ed96607c57d01633e 275 Pfam PF00285 Citrate synthase, C-terminal domain 16 62 3.1E-5 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS20815 c14946f05113fd9ed96607c57d01633e 275 Pfam PF00285 Citrate synthase, C-terminal domain 59 251 8.3E-30 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS20815 c14946f05113fd9ed96607c57d01633e 275 SUPERFAMILY SSF48256 12 255 5.23E-51 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS20815 c14946f05113fd9ed96607c57d01633e 275 Gene3D G3DSA:1.10.230.10 112 220 3.6E-20 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CNX65_RS01665 cdf364d7f41285d13c1aa6eb52f59513 297 SUPERFAMILY SSF48179 179 278 1.05E-25 T 28-03-2018 IPR008927 6-phosphogluconate dehydrogenase C-terminal domain-like GO:0055114 CNX65_RS01665 cdf364d7f41285d13c1aa6eb52f59513 297 Pfam PF10727 Rossmann-like domain 5 126 8.2E-47 T 28-03-2018 IPR019665 Putative oxidoreductase/dehydrogenase, Rossmann-like domain CNX65_RS01665 cdf364d7f41285d13c1aa6eb52f59513 297 Pfam PF10728 Domain of unknown function (DUF2520) 147 272 6.6E-39 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CNX65_RS01665 cdf364d7f41285d13c1aa6eb52f59513 297 Gene3D G3DSA:1.10.1040.20 178 275 4.3E-37 T 28-03-2018 IPR018931 Domain of unknown function DUF2520 CNX65_RS01665 cdf364d7f41285d13c1aa6eb52f59513 297 SUPERFAMILY SSF51735 13 176 7.6E-22 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS01665 cdf364d7f41285d13c1aa6eb52f59513 297 Gene3D G3DSA:3.40.50.720 8 177 4.0E-17 T 28-03-2018 CNX65_RS26425 bf85287b7c59ee2b1ae6f9aa91b44eba 294 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 280 4.8E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS26425 bf85287b7c59ee2b1ae6f9aa91b44eba 294 Gene3D G3DSA:1.10.3720.10 11 293 4.4E-48 T 28-03-2018 CNX65_RS26425 bf85287b7c59ee2b1ae6f9aa91b44eba 294 SUPERFAMILY SSF161098 52 277 1.23E-52 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS00705 198de4d00406d97b8d501f5569cce839 210 Pfam PF13302 Acetyltransferase (GNAT) domain 15 162 3.6E-14 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS00705 198de4d00406d97b8d501f5569cce839 210 Gene3D G3DSA:3.40.630.30 1 203 6.7E-28 T 28-03-2018 CNX65_RS00705 198de4d00406d97b8d501f5569cce839 210 SUPERFAMILY SSF55729 9 170 1.67E-22 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS21550 061c5f22186833bc6fdfcf85a38d01b1 281 Gene3D G3DSA:2.40.50.140 213 281 3.8E-6 T 28-03-2018 CNX65_RS21550 061c5f22186833bc6fdfcf85a38d01b1 281 Gene3D G3DSA:3.40.50.1010 2 165 1.2E-18 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS21550 061c5f22186833bc6fdfcf85a38d01b1 281 Pfam PF01936 NYN domain 6 147 1.7E-13 T 28-03-2018 IPR021139 NYN domain, limkain-b1-type CNX65_RS26290 7cb6ad6f91ec65dcc09e0225801a8f27 435 PRINTS PR00364 Disease resistance protein signature 213 227 3.2E-6 T 28-03-2018 CNX65_RS26290 7cb6ad6f91ec65dcc09e0225801a8f27 435 PRINTS PR00364 Disease resistance protein signature 135 150 3.2E-6 T 28-03-2018 CNX65_RS26290 7cb6ad6f91ec65dcc09e0225801a8f27 435 PRINTS PR00364 Disease resistance protein signature 301 315 3.2E-6 T 28-03-2018 CNX65_RS26290 7cb6ad6f91ec65dcc09e0225801a8f27 435 SUPERFAMILY SSF52540 98 361 1.01E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS26290 7cb6ad6f91ec65dcc09e0225801a8f27 435 Gene3D G3DSA:3.40.50.300 94 254 1.0E-14 T 28-03-2018 CNX65_RS26290 7cb6ad6f91ec65dcc09e0225801a8f27 435 Pfam PF00931 NB-ARC domain 131 366 1.8E-7 T 28-03-2018 IPR002182 NB-ARC GO:0043531 Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-6798695|Reactome: R-HSA-6803207 CNX65_RS27990 dbd407b79709cf7b94e2738b428b8ff9 122 Gene3D G3DSA:2.30.110.10 1 110 4.4E-16 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS27990 dbd407b79709cf7b94e2738b428b8ff9 122 TIGRFAM TIGR03666 Rv2061_F420: PPOX class probable F420-dependent enzyme, Rv2061 family 2 121 3.5E-42 T 28-03-2018 IPR019965 PPOX class F420-dependent enzyme, family Rv2061, putative CNX65_RS27990 dbd407b79709cf7b94e2738b428b8ff9 122 SUPERFAMILY SSF50475 3 99 1.92E-13 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 SUPERFAMILY SSF55486 36 163 6.83E-19 T 28-03-2018 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 Gene3D G3DSA:3.40.390.10 37 167 5.2E-14 T 28-03-2018 IPR024079 Metallopeptidase, catalytic domain GO:0008237 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 Pfam PF02031 Streptomyces extracellular neutral proteinase (M7) family 36 164 2.3E-24 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 ProDom PD016028 PROTEASE METALLOPROTEASE EXTRACELLULAR NEUTRAL SMALL METAL-BINDING ZINC HYDROLASE SNAPALYSIN ZYMOGEN 43 161 1.0E-28 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 126 150 2.3E-15 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 42 68 2.3E-15 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 101 125 2.3E-15 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CNX65_RS12145 647474fdc288ba6dcf4ddae3422dd2fb 183 PRINTS PR00787 Streptomyces extracellular neutral proteinase (M7) family signature 153 167 2.3E-15 T 28-03-2018 IPR000013 Peptidase M7, snapalysin GO:0004222|GO:0005576|GO:0006508|GO:0008270 CNX65_RS20155 e8b51a630bf7958150059e683027709d 103 Gene3D G3DSA:1.10.287.1060 3 101 7.6E-7 T 28-03-2018 CNX65_RS22920 6987cfa65c20b1bf5b3dc2a576df33b0 311 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 106 304 1.9E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS22920 6987cfa65c20b1bf5b3dc2a576df33b0 311 SUPERFAMILY SSF161098 75 298 8.63E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS22920 6987cfa65c20b1bf5b3dc2a576df33b0 311 Gene3D G3DSA:1.10.3720.10 34 310 5.4E-41 T 28-03-2018 CNX65_RS19430 613768b330d64ea6648d56a03ba073c9 217 SMART SM00226 86 211 1.5E-37 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS19430 613768b330d64ea6648d56a03ba073c9 217 Gene3D G3DSA:3.40.50.2300 84 215 1.7E-34 T 28-03-2018 CNX65_RS19430 613768b330d64ea6648d56a03ba073c9 217 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 88 209 2.2E-19 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS19430 613768b330d64ea6648d56a03ba073c9 217 SUPERFAMILY SSF52788 86 209 2.35E-33 T 28-03-2018 IPR023485 Phosphotyrosine protein phosphatase I superfamily CNX65_RS14015 66c64a13ea4b97aa72bc8c2b50cf95e8 632 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 361 596 3.2E-80 T 28-03-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related CNX65_RS27070 a2cb3d91fc73da81d799a61f0a2b23c6 394 Pfam PF12555 Thiamine pyrophosphokinase C terminal 336 385 4.5E-9 T 28-03-2018 IPR022215 Thiamine pyrophosphokinase C-terminal CNX65_RS27070 a2cb3d91fc73da81d799a61f0a2b23c6 394 Gene3D G3DSA:3.40.50.10240 181 256 1.1E-5 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CNX65_RS27070 a2cb3d91fc73da81d799a61f0a2b23c6 394 SUPERFAMILY SSF63999 157 303 7.59E-17 T 28-03-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 CNX65_RS17245 9b20e11256e9ed92f993613c5dfb206d 106 Pfam PF13397 RNA polymerase-binding protein 4 98 2.1E-38 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CNX65_RS17245 9b20e11256e9ed92f993613c5dfb206d 106 Hamap MF_01483 RNA polymerase-binding protein RbpA [rbpA]. 16 106 19.484 T 28-03-2018 IPR025182 RNA polymerase-binding protein RbpA GO:0001000|GO:0045893 CNX65_RS27050 cd02d8177e29c022d444c230d6f71962 141 Pfam PF10825 Protein of unknown function (DUF2752) 49 97 2.4E-19 T 28-03-2018 IPR021215 Protein of unknown function DUF2752 CNX65_RS03100 534fe0dd52d615baf3e175e16a5f2ca7 206 SMART SM00858 28 89 1.9E-7 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CNX65_RS03100 534fe0dd52d615baf3e175e16a5f2ca7 206 Gene3D G3DSA:3.90.1210.10 26 90 1.7E-12 T 28-03-2018 CNX65_RS03100 534fe0dd52d615baf3e175e16a5f2ca7 206 Pfam PF08666 SAF domain 29 88 3.6E-6 T 28-03-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 CNX65_RS26800 b1969d65dfc0fcbcca27fd032937fa0c 137 Gene3D G3DSA:3.10.450.40 2 130 2.7E-42 T 28-03-2018 CNX65_RS26800 b1969d65dfc0fcbcca27fd032937fa0c 137 Pfam PF04965 Gene 25-like lysozyme 27 116 1.4E-24 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CNX65_RS26800 b1969d65dfc0fcbcca27fd032937fa0c 137 SUPERFAMILY SSF160719 22 129 1.18E-35 T 28-03-2018 CNX65_RS32810 0c3b7904ecab13ac2e995d7adbb1c852 196 SUPERFAMILY SSF143243 15 185 9.94E-32 T 28-03-2018 CNX65_RS32810 0c3b7904ecab13ac2e995d7adbb1c852 196 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 28 146 5.8E-26 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32810 0c3b7904ecab13ac2e995d7adbb1c852 196 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 92 149 1.0E-9 T 28-03-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS20585 612935803c730b40a1d545c5c958137a 667 Pfam PF13517 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella 156 231 3.3E-6 T 28-03-2018 CNX65_RS20585 612935803c730b40a1d545c5c958137a 667 Gene3D G3DSA:2.130.10.130 141 332 6.6E-16 T 28-03-2018 CNX65_RS20585 612935803c730b40a1d545c5c958137a 667 Gene3D G3DSA:2.130.10.130 334 555 1.3E-5 T 28-03-2018 CNX65_RS20585 612935803c730b40a1d545c5c958137a 667 Pfam PF07593 ASPIC and UnbV 584 640 6.3E-12 T 28-03-2018 IPR011519 ASPIC/UnbV CNX65_RS20585 612935803c730b40a1d545c5c958137a 667 SUPERFAMILY SSF69318 79 453 9.59E-44 T 28-03-2018 CNX65_RS20585 612935803c730b40a1d545c5c958137a 667 SUPERFAMILY SSF69318 488 553 9.59E-44 T 28-03-2018 CNX65_RS21850 b2b85d600f0c302dab6458cef690fcb7 317 SUPERFAMILY SSF51412 2 306 1.57E-63 T 28-03-2018 CNX65_RS21850 b2b85d600f0c302dab6458cef690fcb7 317 Gene3D G3DSA:3.20.20.70 1 315 3.2E-57 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS21850 b2b85d600f0c302dab6458cef690fcb7 317 Pfam PF03060 Nitronate monooxygenase 2 300 7.4E-56 T 28-03-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 CNX65_RS16610 081641ec16e671e23874969ab284c56c 201 Pfam PF08386 TAP-like protein 40 135 6.8E-23 T 28-03-2018 IPR013595 Peptidase S33 tripeptidyl aminopeptidase-like, C-terminal CNX65_RS16610 081641ec16e671e23874969ab284c56c 201 SUPERFAMILY SSF53474 56 124 6.99E-7 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16610 081641ec16e671e23874969ab284c56c 201 Gene3D G3DSA:3.40.50.1820 2 134 2.0E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS02720 256bf8d61ba68d56e886a1974ea41be6 102 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 1 93 1.3E-6 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CNX65_RS02720 256bf8d61ba68d56e886a1974ea41be6 102 Gene3D G3DSA:1.10.287.1060 1 99 3.3E-9 T 28-03-2018 CNX65_RS13105 3ea1254b11f613403a1f2596a7b17cdd 146 SUPERFAMILY SSF160424 9 144 7.06E-27 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS02395 35747f2ed0695c767ad236b7fccc5ef1 153 Gene3D G3DSA:1.10.10.10 4 153 7.5E-20 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS02395 35747f2ed0695c767ad236b7fccc5ef1 153 SMART SM00347 31 132 1.1E-12 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS02395 35747f2ed0695c767ad236b7fccc5ef1 153 Pfam PF01047 MarR family 56 97 3.6E-11 T 28-03-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 CNX65_RS02395 35747f2ed0695c767ad236b7fccc5ef1 153 SUPERFAMILY SSF46785 28 145 1.82E-21 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS28975 39eb3960246692e135fdf2f7c04057c2 245 Gene3D G3DSA:3.40.50.150 14 225 1.9E-27 T 28-03-2018 CNX65_RS28975 39eb3960246692e135fdf2f7c04057c2 245 SUPERFAMILY SSF53335 39 199 2.63E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS28975 39eb3960246692e135fdf2f7c04057c2 245 Pfam PF08241 Methyltransferase domain 56 150 1.5E-15 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS20240 60b0cc4a41406663a02fb85b23919797 332 SUPERFAMILY SSF101478 3 326 1.31E-56 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS20240 60b0cc4a41406663a02fb85b23919797 332 Gene3D G3DSA:1.10.4080.10 4 331 1.5E-69 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS20240 60b0cc4a41406663a02fb85b23919797 332 Pfam PF03747 ADP-ribosylglycohydrolase 9 312 6.1E-57 T 28-03-2018 IPR005502 ADP-ribosylation/Crystallin J1 CNX65_RS07100 f96762453864801d3a568861807f723c 85 Gene3D G3DSA:3.10.350.10 25 80 1.5E-6 T 28-03-2018 CNX65_RS07100 f96762453864801d3a568861807f723c 85 Pfam PF01476 LysM domain 30 79 7.7E-5 T 28-03-2018 IPR018392 LysM domain CNX65_RS24455 7453e27b2fa1c4c498eb04dc393dca82 634 Pfam PF01757 Acyltransferase family 297 616 5.5E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS10535 90e6eb108bded3be867f37b08467bfd3 158 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 9 103 8.8E-20 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CNX65_RS10535 90e6eb108bded3be867f37b08467bfd3 158 SUPERFAMILY SSF53927 8 136 6.55E-41 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS10535 90e6eb108bded3be867f37b08467bfd3 158 Gene3D G3DSA:3.40.140.10 2 158 7.4E-36 T 28-03-2018 CNX65_RS23760 8fb7d032ead3b41468e8ae13ca1674d0 267 Pfam PF13649 Methyltransferase domain 41 135 6.8E-18 T 28-03-2018 CNX65_RS23760 8fb7d032ead3b41468e8ae13ca1674d0 267 Gene3D G3DSA:3.40.50.150 3 257 3.5E-35 T 28-03-2018 CNX65_RS23760 8fb7d032ead3b41468e8ae13ca1674d0 267 SUPERFAMILY SSF53335 4 209 1.35E-34 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS11170 e6c6dd37d9cdc302d56f3ad07413a317 356 Pfam PF14011 EspG family 102 350 5.4E-50 T 28-03-2018 IPR025734 EspG family CNX65_RS17415 0a23435da75a846141863916657dec6b 215 Gene3D G3DSA:1.10.357.10 70 179 2.0E-4 T 28-03-2018 CNX65_RS17415 0a23435da75a846141863916657dec6b 215 Gene3D G3DSA:1.10.10.60 2 39 1.2E-7 T 28-03-2018 CNX65_RS17415 0a23435da75a846141863916657dec6b 215 Gene3D G3DSA:1.10.260.40 40 69 2.8E-5 T 28-03-2018 CNX65_RS17415 0a23435da75a846141863916657dec6b 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 63 1.0E-4 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS17415 0a23435da75a846141863916657dec6b 215 SUPERFAMILY SSF46689 5 85 1.95E-11 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS04240 4cf1a8253f96fb011e8fbd4870cfc582 549 Pfam PF09972 Predicted membrane protein (DUF2207) 44 502 7.4E-41 T 28-03-2018 IPR018702 Protein of unknown function DUF2207, membrane CNX65_RS20250 aebeb88663f5d2ffd1a5352ae48f6047 647 SUPERFAMILY SSF53300 83 248 3.89E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS20250 aebeb88663f5d2ffd1a5352ae48f6047 647 SUPERFAMILY SSF141072 341 454 7.46E-27 T 28-03-2018 CNX65_RS20250 aebeb88663f5d2ffd1a5352ae48f6047 647 SMART SM00237 335 428 2.9E-10 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 CNX65_RS20250 aebeb88663f5d2ffd1a5352ae48f6047 647 Gene3D G3DSA:3.40.50.410 81 220 1.6E-20 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS20250 aebeb88663f5d2ffd1a5352ae48f6047 647 Pfam PF03160 Calx-beta domain 346 427 1.4E-14 T 28-03-2018 IPR003644 Na-Ca exchanger/integrin-beta4 GO:0007154|GO:0016021 CNX65_RS20000 4769a6e8e434ad7b92a35c959b3b76d4 181 Pfam PF13671 AAA domain 4 125 2.4E-12 T 28-03-2018 CNX65_RS20000 4769a6e8e434ad7b92a35c959b3b76d4 181 Gene3D G3DSA:3.40.50.300 1 175 9.6E-17 T 28-03-2018 CNX65_RS20000 4769a6e8e434ad7b92a35c959b3b76d4 181 SUPERFAMILY SSF52540 1 121 1.1E-14 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24245 46a40dcd6952a6972758507834cdbd25 120 Gene3D G3DSA:3.30.750.24 5 112 6.3E-11 T 28-03-2018 IPR002645 STAS domain CNX65_RS24245 46a40dcd6952a6972758507834cdbd25 120 Pfam PF13466 STAS domain 20 98 1.4E-12 T 28-03-2018 IPR002645 STAS domain CNX65_RS24245 46a40dcd6952a6972758507834cdbd25 120 SUPERFAMILY SSF52091 8 106 5.49E-16 T 28-03-2018 IPR002645 STAS domain CNX65_RS03770 c309521b0ce69e54e63cdcf42d9db227 392 ProSitePatterns PS00211 ABC transporters family signature. 172 186 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS03770 c309521b0ce69e54e63cdcf42d9db227 392 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 250 335 3.1E-23 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS03770 c309521b0ce69e54e63cdcf42d9db227 392 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 251 315 4.5E-17 T 28-03-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 CNX65_RS03770 c309521b0ce69e54e63cdcf42d9db227 392 SUPERFAMILY SSF52540 22 269 9.76E-64 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS03770 c309521b0ce69e54e63cdcf42d9db227 392 SMART SM00382 51 249 3.4E-13 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS03770 c309521b0ce69e54e63cdcf42d9db227 392 Pfam PF00005 ABC transporter 43 199 3.6E-26 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS03770 c309521b0ce69e54e63cdcf42d9db227 392 Gene3D G3DSA:3.40.50.300 19 349 2.8E-74 T 28-03-2018 CNX65_RS32615 5b0c18db9f80168e793fb6ad539c7f31 139 SUPERFAMILY SSF54637 5 129 5.69E-27 T 28-03-2018 IPR029069 HotDog domain CNX65_RS32615 5b0c18db9f80168e793fb6ad539c7f31 139 Pfam PF01575 MaoC like domain 17 107 1.4E-22 T 28-03-2018 IPR002539 MaoC-like domain CNX65_RS32615 5b0c18db9f80168e793fb6ad539c7f31 139 Gene3D G3DSA:3.10.129.10 2 139 4.7E-34 T 28-03-2018 CNX65_RS03390 f85eafec7c69fbc3661ea3f09c0be35e 493 SUPERFAMILY SSF53474 30 476 1.15E-69 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03390 f85eafec7c69fbc3661ea3f09c0be35e 493 Gene3D G3DSA:3.40.50.1820 15 492 5.9E-59 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03390 f85eafec7c69fbc3661ea3f09c0be35e 493 Pfam PF00450 Serine carboxypeptidase 69 229 1.7E-9 T 28-03-2018 IPR001563 Peptidase S10, serine carboxypeptidase GO:0004185|GO:0006508 CNX65_RS31790 4aacbe069d145d6849bb0d7b0e1b138d 268 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 3 241 5.7E-31 T 28-03-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase CNX65_RS22260 ccf0a1f4db1b86e3d946261b2009a5d9 98 Gene3D G3DSA:3.30.70.100 1 93 9.1E-18 T 28-03-2018 CNX65_RS22260 ccf0a1f4db1b86e3d946261b2009a5d9 98 Pfam PF03992 Antibiotic biosynthesis monooxygenase 2 71 1.9E-11 T 28-03-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain CNX65_RS22260 ccf0a1f4db1b86e3d946261b2009a5d9 98 SUPERFAMILY SSF54909 2 90 2.47E-16 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS08680 e22bee187258c2e2f86fd269c1407cc9 465 Pfam PF04932 O-Antigen ligase 225 361 1.5E-6 T 28-03-2018 IPR007016 O-antigen ligase-related CNX65_RS16770 90287ff0b33e72e60f04ca2528b7a723 215 Pfam PF06197 Protein of unknown function (DUF998) 22 198 4.2E-30 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CNX65_RS26860 de4f148a21b10453ae7e2e3ebad33cb0 195 Pfam PF14065 Protein of unknown function (DUF4255) 4 178 6.6E-47 T 28-03-2018 IPR025351 Protein of unknown function DUF4255 CNX65_RS29485 d5baa703f75fdd5f022da9711a98567f 380 PIRSF PIRSF001434 56 380 1.2E-91 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS29485 d5baa703f75fdd5f022da9711a98567f 380 SUPERFAMILY SSF53383 62 379 5.27E-78 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS29485 d5baa703f75fdd5f022da9711a98567f 380 Gene3D G3DSA:3.40.640.10 33 273 4.8E-34 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS29485 d5baa703f75fdd5f022da9711a98567f 380 Gene3D G3DSA:3.90.1150.10 274 380 5.5E-26 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS29485 d5baa703f75fdd5f022da9711a98567f 380 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 65 379 1.2E-73 T 28-03-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 CNX65_RS25175 e1f0518ddcf005024f4bdb0e22666eba 115 Gene3D G3DSA:1.20.1440.110 44 114 8.0E-4 T 28-03-2018 CNX65_RS11075 80a800e966e649e25a16d54482cba3c7 532 SUPERFAMILY SSF53850 76 527 4.22E-54 T 28-03-2018 CNX65_RS11075 80a800e966e649e25a16d54482cba3c7 532 Gene3D G3DSA:3.40.190.10 217 530 4.2E-23 T 28-03-2018 CNX65_RS11075 80a800e966e649e25a16d54482cba3c7 532 Pfam PF13416 Bacterial extracellular solute-binding protein 101 347 1.8E-11 T 28-03-2018 CNX65_RS11075 80a800e966e649e25a16d54482cba3c7 532 Gene3D G3DSA:3.40.190.10 79 216 4.0E-9 T 28-03-2018 CNX65_RS20480 7fb619656b2adf7b2939fb9480b635e9 470 SUPERFAMILY SSF53448 165 389 2.06E-33 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS20480 7fb619656b2adf7b2939fb9480b635e9 470 Gene3D G3DSA:3.90.550.10 154 412 1.4E-28 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS20480 7fb619656b2adf7b2939fb9480b635e9 470 Pfam PF00535 Glycosyl transferase family 2 182 334 1.1E-19 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS21940 90126220ce3570068414e94bf81743c9 323 Pfam PF01040 UbiA prenyltransferase family 24 244 5.0E-28 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CNX65_RS08195 c3b244750b20f696d0820ea8d2e312a0 209 Gene3D G3DSA:1.10.10.10 130 190 0.099 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08195 c3b244750b20f696d0820ea8d2e312a0 209 Gene3D G3DSA:1.10.10.10 7 129 0.0049 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS29800 14f36d9f598e653443e0955f076b8bcf 248 Pfam PF08241 Methyltransferase domain 44 134 8.5E-21 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS29800 14f36d9f598e653443e0955f076b8bcf 248 SUPERFAMILY SSF53335 22 190 2.03E-36 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS29800 14f36d9f598e653443e0955f076b8bcf 248 Gene3D G3DSA:3.40.50.150 12 208 5.3E-33 T 28-03-2018 CNX65_RS34310 2a4f61b2374beaca722855a08fa7c148 127 Gene3D G3DSA:3.10.180.10 1 127 2.1E-19 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS34310 2a4f61b2374beaca722855a08fa7c148 127 SUPERFAMILY SSF54593 7 118 7.23E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS18035 04028b994e0203645372c70192301e21 340 Pfam PF00296 Luciferase-like monooxygenase 9 258 3.7E-24 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS18035 04028b994e0203645372c70192301e21 340 SUPERFAMILY SSF51679 7 333 8.51E-55 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS18035 04028b994e0203645372c70192301e21 340 Gene3D G3DSA:3.20.20.30 2 338 2.2E-58 T 28-03-2018 CNX65_RS08350 21c69076b96797312de900be7b6806fa 374 Pfam PF04235 Protein of unknown function (DUF418) 210 363 1.9E-30 T 28-03-2018 IPR007349 Domain of unknown function DUF418 CNX65_RS09430 89616b8b33791465e69baf8774c25beb 1104 Pfam PF13569 Domain of unknown function (DUF4132) 841 1019 2.0E-50 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS03175 f0efe6e42049dd2ec9af9d60f094c608 274 PIRSF PIRSF005902 10 274 2.4E-70 T 28-03-2018 IPR001130 TatD family GO:0016788 CNX65_RS03175 f0efe6e42049dd2ec9af9d60f094c608 274 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 19 271 1.5E-79 T 28-03-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 CNX65_RS03175 f0efe6e42049dd2ec9af9d60f094c608 274 Gene3D G3DSA:3.20.20.140 17 274 2.3E-80 T 28-03-2018 CNX65_RS03175 f0efe6e42049dd2ec9af9d60f094c608 274 SUPERFAMILY SSF51556 20 272 4.54E-78 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS03175 f0efe6e42049dd2ec9af9d60f094c608 274 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 207 223 - T 28-03-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 CNX65_RS03175 f0efe6e42049dd2ec9af9d60f094c608 274 Pfam PF01026 TatD related DNase 20 270 6.6E-69 T 28-03-2018 IPR001130 TatD family GO:0016788 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 Pfam PF00285 Citrate synthase, C-terminal domain 54 420 3.1E-136 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 PRINTS PR00143 Citrate synthase signature 227 242 3.8E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 PRINTS PR00143 Citrate synthase signature 305 325 3.8E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 PRINTS PR00143 Citrate synthase signature 173 186 3.8E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 PRINTS PR00143 Citrate synthase signature 249 277 3.8E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 PRINTS PR00143 Citrate synthase signature 388 402 3.8E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 PRINTS PR00143 Citrate synthase signature 368 384 3.8E-54 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 Gene3D G3DSA:1.10.230.10 291 388 3.5E-34 T 28-03-2018 IPR016143 Citrate synthase-like, small alpha subdomain CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 PIRSF PIRSF001369 45 437 1.4E-156 T 28-03-2018 IPR024176 Citrate synthase, bacterial-type CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 TIGRFAM TIGR01798 cit_synth_I: citrate (Si)-synthase 23 431 6.5E-182 T 28-03-2018 IPR010953 Citrate synthase, type I GO:0004108|GO:0005737 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 ProSitePatterns PS00480 Citrate synthase signature. 312 324 - T 28-03-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 Gene3D G3DSA:1.10.580.10 25 290 1.9E-91 T 28-03-2018 IPR016142 Citrate synthase-like, large alpha subdomain CNX65_RS02680 965cad3ba63b6a174c68f0aef71783ee 437 SUPERFAMILY SSF48256 13 437 3.4E-159 T 28-03-2018 IPR002020 Citrate synthase GO:0046912 CNX65_RS14095 b0175de98c4ca68f5e767733f13cd088 487 Gene3D G3DSA:3.40.309.10 275 469 7.6E-72 T 28-03-2018 CNX65_RS14095 b0175de98c4ca68f5e767733f13cd088 487 SUPERFAMILY SSF53720 15 486 6.41E-164 T 28-03-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0008152|GO:0016491|GO:0055114 CNX65_RS14095 b0175de98c4ca68f5e767733f13cd088 487 Pfam PF00171 Aldehyde dehydrogenase family 30 483 2.4E-164 T 28-03-2018 IPR015590 Aldehyde dehydrogenase domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS14095 b0175de98c4ca68f5e767733f13cd088 487 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 258 265 - T 28-03-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0008152|GO:0016491|GO:0055114 CNX65_RS14095 b0175de98c4ca68f5e767733f13cd088 487 Gene3D G3DSA:3.40.605.10 11 274 3.1E-97 T 28-03-2018 IPR016162 Aldehyde dehydrogenase N-terminal domain GO:0008152|GO:0016491|GO:0055114 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 SUPERFAMILY SSF51905 6 185 2.16E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 SUPERFAMILY SSF51905 281 362 2.16E-55 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 Gene3D G3DSA:3.50.50.60 3 393 1.4E-52 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 Pfam PF01494 FAD binding domain 6 359 2.1E-88 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 345 361 3.0E-44 T 28-03-2018 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 294 309 3.0E-44 T 28-03-2018 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 8 30 3.0E-44 T 28-03-2018 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 164 179 3.0E-44 T 28-03-2018 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 327 345 3.0E-44 T 28-03-2018 CNX65_RS15935 a8bd07b4f33bd6e7b773c56000b5739a 538 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 309 325 3.0E-44 T 28-03-2018 CNX65_RS05780 8a155d0bc0536a76ddc03d2ef123724e 516 SUPERFAMILY SSF51905 5 298 2.92E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS05780 8a155d0bc0536a76ddc03d2ef123724e 516 SUPERFAMILY SSF51905 480 512 2.92E-28 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS05780 8a155d0bc0536a76ddc03d2ef123724e 516 Pfam PF13450 NAD(P)-binding Rossmann-like domain 9 46 4.7E-8 T 28-03-2018 CNX65_RS05780 8a155d0bc0536a76ddc03d2ef123724e 516 Gene3D G3DSA:3.50.50.60 2 516 4.7E-27 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS26640 d38ddb0aef2744a0842202a76f59aea6 120 SUPERFAMILY SSF54427 1 114 2.68E-13 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS26640 d38ddb0aef2744a0842202a76f59aea6 120 Gene3D G3DSA:3.10.450.50 3 117 1.8E-9 T 28-03-2018 CNX65_RS09705 33ed62f44a6013ac7ac97d769c337c8f 55 Pfam PF04149 Domain of unknown function (DUF397) 2 53 2.6E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS29320 0a1bd4274dff777fc1b96eb262e28e2f 181 Pfam PF14430 Immunity protein Imm1 49 170 1.3E-30 T 28-03-2018 IPR025680 Immunity protein Imm1 CNX65_RS28535 36ca5bbdbc9866b4fd7c6f5c89d42926 188 Gene3D G3DSA:3.40.630.30 5 181 1.4E-27 T 28-03-2018 CNX65_RS28535 36ca5bbdbc9866b4fd7c6f5c89d42926 188 Pfam PF00583 Acetyltransferase (GNAT) family 56 153 1.5E-7 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS28535 36ca5bbdbc9866b4fd7c6f5c89d42926 188 SUPERFAMILY SSF55729 5 160 1.77E-24 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS07205 aaea047512f4c858a82a16755ac0d3b7 174 Pfam PF07336 Putative stress-induced transcription regulator 2 128 2.6E-16 T 28-03-2018 IPR010852 Putative stress-induced transcription regulator CNX65_RS07205 aaea047512f4c858a82a16755ac0d3b7 174 Gene3D G3DSA:1.10.3300.10 1 174 4.3E-35 T 28-03-2018 IPR023286 ABATE domain CNX65_RS07205 aaea047512f4c858a82a16755ac0d3b7 174 Pfam PF11706 CGNR zinc finger 133 172 3.9E-9 T 28-03-2018 IPR021005 Zinc finger, CGNR CNX65_RS07205 aaea047512f4c858a82a16755ac0d3b7 174 SUPERFAMILY SSF160904 3 171 1.7E-30 T 28-03-2018 CNX65_RS00710 f1c13f18390c602a22c0f642e5c915f0 506 Pfam PF02225 PA domain 136 223 7.8E-16 T 28-03-2018 IPR003137 PA domain CNX65_RS00710 f1c13f18390c602a22c0f642e5c915f0 506 SUPERFAMILY SSF53187 230 469 1.46E-57 T 28-03-2018 CNX65_RS00710 f1c13f18390c602a22c0f642e5c915f0 506 SUPERFAMILY SSF53187 47 96 1.46E-57 T 28-03-2018 CNX65_RS00710 f1c13f18390c602a22c0f642e5c915f0 506 SUPERFAMILY SSF52025 126 221 1.28E-14 T 28-03-2018 CNX65_RS00710 f1c13f18390c602a22c0f642e5c915f0 506 Pfam PF04389 Peptidase family M28 246 462 4.2E-41 T 28-03-2018 IPR007484 Peptidase M28 CNX65_RS00710 f1c13f18390c602a22c0f642e5c915f0 506 Gene3D G3DSA:3.40.630.10 44 477 5.2E-55 T 28-03-2018 CNX65_RS15065 8064dd9ad7209f430f957d9bff0db372 718 Gene3D G3DSA:2.60.60.30 483 624 3.0E-10 T 28-03-2018 CNX65_RS15065 8064dd9ad7209f430f957d9bff0db372 718 Gene3D G3DSA:3.40.50.720 3 230 0.02 T 28-03-2018 CNX65_RS19855 8e6b64258b214419a513c064fd6ea8b3 140 Pfam PF03779 SPW repeat 88 133 6.1E-5 T 28-03-2018 IPR005530 SPW repeat CNX65_RS19855 8e6b64258b214419a513c064fd6ea8b3 140 Pfam PF03779 SPW repeat 31 77 9.4E-6 T 28-03-2018 IPR005530 SPW repeat CNX65_RS33090 c74abef8119a6b6900b747ab2e8cabff 349 Pfam PF09471 IgA Peptidase M64 67 306 2.0E-59 T 28-03-2018 IPR019026 Peptidase M64, IgA CNX65_RS08935 247c6a514ec66c9220e237052b5e64cb 75 Pfam PF06305 Lipopolysaccharide assembly protein A domain 16 68 8.5E-12 T 28-03-2018 IPR010445 Lipopolysaccharide assembly protein A domain GO:0005887 CNX65_RS30675 3b1ae6db6f125f9c37c758704ec27442 729 SUPERFAMILY SSF48619 109 184 1.68E-6 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CNX65_RS30675 3b1ae6db6f125f9c37c758704ec27442 729 Pfam PF09056 Prokaryotic phospholipase A2 109 184 1.0E-7 T 28-03-2018 IPR015141 Phospholipase A2, prokaryotic/fungal CNX65_RS30675 3b1ae6db6f125f9c37c758704ec27442 729 Gene3D G3DSA:1.20.90.10 96 188 1.3E-10 T 28-03-2018 IPR016090 Phospholipase A2 domain GO:0004623|GO:0006644|GO:0050482 KEGG: 00564+3.1.1.4|KEGG: 00565+3.1.1.4|KEGG: 00590+3.1.1.4|KEGG: 00591+3.1.1.4|KEGG: 00592+3.1.1.4|MetaCyc: PWY-6803|MetaCyc: PWY-7409|MetaCyc: PWY-7416|MetaCyc: PWY-7417|MetaCyc: PWY-7783 CNX65_RS30675 3b1ae6db6f125f9c37c758704ec27442 729 Pfam PF01757 Acyltransferase family 256 554 9.4E-10 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS02480 60b61d16d95c35fc3739c63c4be8b91e 81 Pfam PF10745 Protein of unknown function (DUF2530) 6 80 3.6E-30 T 28-03-2018 IPR019681 Protein of unknown function DUF2530 CNX65_RS34985 e65efcf4928b679451a4c2b0e7abceb3 502 SUPERFAMILY SSF56112 20 264 1.34E-6 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS34985 e65efcf4928b679451a4c2b0e7abceb3 502 Gene3D G3DSA:1.10.510.10 17 176 0.0012 T 28-03-2018 CNX65_RS34985 e65efcf4928b679451a4c2b0e7abceb3 502 Gene3D G3DSA:1.10.510.10 178 268 2.9E-4 T 28-03-2018 CNX65_RS15605 1828ed8a11d9582ec586fff64b6483db 106 Gene3D G3DSA:1.10.287.1060 6 100 2.8E-4 T 28-03-2018 CNX65_RS15605 1828ed8a11d9582ec586fff64b6483db 106 Pfam PF00934 PE family 9 80 1.1E-4 T 28-03-2018 IPR000084 PE-PGRS family, N-terminal CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 Gene3D G3DSA:3.40.50.720 1 262 5.4E-57 T 28-03-2018 CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 Pfam PF00106 short chain dehydrogenase 8 190 4.3E-44 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 152 171 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 132 140 1.3E-10 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 SUPERFAMILY SSF51735 7 257 1.04E-59 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 9 26 3.8E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 222 242 3.8E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 152 171 3.8E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 3.8E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 173 190 3.8E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS12310 6bd6a216a50179cab13300aafd722ee0 262 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 126 142 3.8E-34 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS19085 7b2956cc382ebd1549f9eeae01d01453 115 TIGRFAM TIGR03462 CarR_dom_SF: lycopene cyclase domain 5 94 3.7E-19 T 28-03-2018 IPR017825 Lycopene cyclase domain GO:0016872 KEGG: 00906+2.5.1.32+5.5.1.19|MetaCyc: PWY-5943|MetaCyc: PWY-5947|MetaCyc: PWY-7591 CNX65_RS16600 7c4fd3bc52363f95bbef7e503be656a7 181 Gene3D G3DSA:3.40.430.10 2 177 5.0E-28 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS16600 7c4fd3bc52363f95bbef7e503be656a7 181 SUPERFAMILY SSF53597 4 179 1.31E-22 T 28-03-2018 IPR024072 Dihydrofolate reductase-like domain Reactome: R-HSA-196757 CNX65_RS16600 7c4fd3bc52363f95bbef7e503be656a7 181 Pfam PF01872 RibD C-terminal domain 6 173 3.0E-13 T 28-03-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 CNX65_RS09610 a9d5955132509e4414bbcc75a8c83830 685 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 93 248 1.5E-29 T 28-03-2018 CNX65_RS03990 22e3fd993b35fe54f12c2c449993538c 420 Gene3D G3DSA:3.40.190.10 145 418 2.4E-43 T 28-03-2018 CNX65_RS03990 22e3fd993b35fe54f12c2c449993538c 420 Pfam PF01547 Bacterial extracellular solute-binding protein 45 332 4.2E-31 T 28-03-2018 IPR006059 Solute-binding family 1 GO:0006810 CNX65_RS03990 22e3fd993b35fe54f12c2c449993538c 420 SUPERFAMILY SSF53850 44 406 9.66E-68 T 28-03-2018 CNX65_RS19590 197efd51fd624fb144266336483ff51a 378 SUPERFAMILY SSF47203 246 372 4.36E-8 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS19590 197efd51fd624fb144266336483ff51a 378 SUPERFAMILY SSF56645 38 225 1.26E-23 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS19590 197efd51fd624fb144266336483ff51a 378 Gene3D G3DSA:1.20.140.10 270 374 9.2E-5 T 28-03-2018 CNX65_RS19590 197efd51fd624fb144266336483ff51a 378 Gene3D G3DSA:2.40.110.10 88 228 5.6E-10 T 28-03-2018 CNX65_RS19590 197efd51fd624fb144266336483ff51a 378 Gene3D G3DSA:1.10.540.10 2 87 3.9E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS10400 bf8d1081cefa65c5c12092625df9d02b 124 SUPERFAMILY SSF46785 21 82 1.26E-7 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS10400 bf8d1081cefa65c5c12092625df9d02b 124 Gene3D G3DSA:1.10.10.10 20 102 8.5E-9 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS16350 341e76d8ad042709d847ac4ae8cab90c 362 SUPERFAMILY SSF103473 4 359 3.01E-47 T 28-03-2018 IPR020846 Major facilitator superfamily domain CNX65_RS16350 341e76d8ad042709d847ac4ae8cab90c 362 PRINTS PR01036 Tetracycline resistance protein TetB signature 78 98 2.9E-5 T 28-03-2018 CNX65_RS16350 341e76d8ad042709d847ac4ae8cab90c 362 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 132 2.9E-5 T 28-03-2018 CNX65_RS16350 341e76d8ad042709d847ac4ae8cab90c 362 Gene3D G3DSA:1.20.1250.20 1 173 6.9E-30 T 28-03-2018 CNX65_RS16350 341e76d8ad042709d847ac4ae8cab90c 362 Gene3D G3DSA:1.20.1250.20 174 362 1.3E-5 T 28-03-2018 CNX65_RS16350 341e76d8ad042709d847ac4ae8cab90c 362 Pfam PF07690 Major Facilitator Superfamily 2 323 6.8E-34 T 28-03-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 CNX65_RS28575 3fcf99af81fd36be0a2df5799d8e2fee 159 Gene3D G3DSA:1.10.260.40 11 154 3.0E-9 T 28-03-2018 CNX65_RS28575 3fcf99af81fd36be0a2df5799d8e2fee 159 SUPERFAMILY SSF47413 21 61 1.27E-7 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS18955 dd3d6d79082c7f489114401cb591945f 335 Gene3D G3DSA:1.10.510.10 80 291 8.8E-12 T 28-03-2018 CNX65_RS18955 dd3d6d79082c7f489114401cb591945f 335 SUPERFAMILY SSF56112 102 316 3.93E-13 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 229 247 3.3E-26 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 14 31 3.3E-26 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 128 150 3.3E-26 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 87 108 3.3E-26 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 PRINTS PR01790 Senescence marker protein-30 (SMP30) family signature 187 204 3.3E-26 T 28-03-2018 IPR005511 Senescence marker protein-30 (SMP-30) CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 Gene3D G3DSA:2.120.10.30 1 267 6.7E-32 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 SUPERFAMILY SSF63829 7 267 5.56E-47 T 28-03-2018 CNX65_RS05080 049f50982d727f30517181c60dd90f0a 278 Pfam PF08450 SMP-30/Gluconolaconase/LRE-like region 13 248 1.2E-58 T 28-03-2018 IPR013658 SMP-30/Gluconolactonase/LRE-like region CNX65_RS05875 364b65824d8d08153178d2f562be433c 85 SUPERFAMILY SSF54862 3 62 4.57E-8 T 28-03-2018 CNX65_RS05875 364b65824d8d08153178d2f562be433c 85 Gene3D G3DSA:3.30.70.20 2 70 6.9E-4 T 28-03-2018 CNX65_RS05875 364b65824d8d08153178d2f562be433c 85 Pfam PF13459 4Fe-4S single cluster domain 4 60 8.2E-10 T 28-03-2018 CNX65_RS28405 e3ae62223dd5c8d24999eff518704bba 288 Pfam PF04012 PspA/IM30 family 3 239 5.7E-48 T 28-03-2018 IPR007157 PspA/IM30 CNX65_RS07595 93b2f0f934816e067eea938bb081e99f 254 Pfam PF14011 EspG family 7 249 2.5E-65 T 28-03-2018 IPR025734 EspG family CNX65_RS24065 a8886cb8626c3327b7ed12b155ef9edc 150 Pfam PF14433 SUKH-3 immunity protein 33 143 1.1E-8 T 28-03-2018 IPR025850 SUKH-3 immunity protein CNX65_RS10500 a49428886c33a04128005ce9025e453f 378 SUPERFAMILY SSF53850 61 344 9.93E-41 T 28-03-2018 CNX65_RS10500 a49428886c33a04128005ce9025e453f 378 Pfam PF13343 Bacterial extracellular solute-binding protein 129 329 1.4E-25 T 28-03-2018 CNX65_RS10500 a49428886c33a04128005ce9025e453f 378 Gene3D G3DSA:3.40.190.10 169 377 4.3E-26 T 28-03-2018 CNX65_RS10500 a49428886c33a04128005ce9025e453f 378 Gene3D G3DSA:3.40.190.10 58 168 1.4E-7 T 28-03-2018 CNX65_RS31890 5c0aa1058680ba8142d880de8ec905a1 99 Pfam PF11222 Protein of unknown function (DUF3017) 17 89 1.1E-19 T 28-03-2018 IPR021385 Protein of unknown function DUF3017 CNX65_RS32380 1e5f79f9c73910848f65f668793723f1 132 SUPERFAMILY SSF56047 3 132 4.58E-45 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32380 1e5f79f9c73910848f65f668793723f1 132 Gene3D G3DSA:3.30.1370.30 1 67 5.6E-27 T 28-03-2018 CNX65_RS32380 1e5f79f9c73910848f65f668793723f1 132 Gene3D G3DSA:3.30.1490.10 69 130 2.0E-19 T 28-03-2018 CNX65_RS32380 1e5f79f9c73910848f65f668793723f1 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 31.787 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS32380 1e5f79f9c73910848f65f668793723f1 132 Pfam PF00410 Ribosomal protein S8 5 132 3.9E-50 T 28-03-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-975956|Reactome: R-HSA-975957 CNX65_RS21570 b9c481e6064e53e736c5ed5cc46c12bc 261 Gene3D G3DSA:3.40.50.1820 2 243 1.4E-16 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21570 b9c481e6064e53e736c5ed5cc46c12bc 261 SUPERFAMILY SSF53474 12 110 3.5E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21570 b9c481e6064e53e736c5ed5cc46c12bc 261 SUPERFAMILY SSF53474 172 241 3.5E-17 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS03970 79de3b92627ce540c599d38275fb7893 285 Pfam PF04655 Aminoglycoside/hydroxyurea antibiotic resistance kinase 33 265 1.1E-41 T 28-03-2018 IPR006748 Aminoglycoside/hydroxyurea antibiotic resistance kinase GO:0006468|GO:0016773|GO:0019748 CNX65_RS03970 79de3b92627ce540c599d38275fb7893 285 SUPERFAMILY SSF56112 17 221 2.37E-11 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS05580 54be9f1ac4d1432a280a66f4ea660100 198 Pfam PF12079 Protein of unknown function (DUF3558) 18 171 8.6E-12 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS20350 623b7eb3b37f5e3adc08ef7cc8cbedea 78 Gene3D G3DSA:2.60.120.10 1 74 5.2E-10 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS20350 623b7eb3b37f5e3adc08ef7cc8cbedea 78 SUPERFAMILY SSF51182 2 64 1.38E-9 T 28-03-2018 IPR011051 RmlC-like cupin domain CNX65_RS23400 dbf7c3936bce682467dbed52e9a4a721 179 SUPERFAMILY SSF50475 21 178 1.42E-48 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS23400 dbf7c3936bce682467dbed52e9a4a721 179 Gene3D G3DSA:2.30.110.10 18 179 3.3E-46 T 28-03-2018 IPR012349 FMN-binding split barrel GO:0048037 CNX65_RS23400 dbf7c3936bce682467dbed52e9a4a721 179 Pfam PF01613 Flavin reductase like domain 30 178 2.6E-36 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS23400 dbf7c3936bce682467dbed52e9a4a721 179 SMART SM00903 30 177 1.0E-53 T 28-03-2018 IPR002563 Flavin reductase like domain GO:0010181 CNX65_RS15860 fff3efb7e8050d343aaae1dfe1b729fe 121 Pfam PF04237 YjbR 25 100 2.0E-10 T 28-03-2018 IPR007351 Uncharacterised protein YjbR CNX65_RS15860 fff3efb7e8050d343aaae1dfe1b729fe 121 SUPERFAMILY SSF142906 25 117 2.35E-9 T 28-03-2018 CNX65_RS33725 96d393cce30b4602be3e6e611c724f3f 352 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 50 346 3.1E-84 T 28-03-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 CNX65_RS33725 96d393cce30b4602be3e6e611c724f3f 352 Gene3D G3DSA:1.10.3720.10 46 343 7.0E-31 T 28-03-2018 CNX65_RS33725 96d393cce30b4602be3e6e611c724f3f 352 SUPERFAMILY SSF161098 75 341 3.16E-29 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS33725 96d393cce30b4602be3e6e611c724f3f 352 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 131 344 1.2E-14 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS04435 de104b4249ccaee8b03646a4a776aa92 292 SUPERFAMILY SSF53474 4 286 5.88E-29 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04435 de104b4249ccaee8b03646a4a776aa92 292 Gene3D G3DSA:3.40.50.1820 2 289 4.0E-24 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS04435 de104b4249ccaee8b03646a4a776aa92 292 Pfam PF12697 Alpha/beta hydrolase family 23 282 3.4E-15 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS34015 24d2c9148f31ac2ed8330f76bd8b88d4 219 Gene3D G3DSA:3.20.20.370 16 209 2.4E-6 T 28-03-2018 CNX65_RS34015 24d2c9148f31ac2ed8330f76bd8b88d4 219 SUPERFAMILY SSF88713 24 139 4.08E-6 T 28-03-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 CNX65_RS34015 24d2c9148f31ac2ed8330f76bd8b88d4 219 Pfam PF10096 Uncharacterized protein conserved in bacteria (DUF2334) 22 135 6.3E-11 T 28-03-2018 IPR018763 Protein of unknown function DUF2334 CNX65_RS17605 ac0e5b678bbd93946a54e965895aebc3 275 Gene3D G3DSA:3.30.1360.130 214 267 8.5E-13 T 28-03-2018 CNX65_RS17605 ac0e5b678bbd93946a54e965895aebc3 275 SUPERFAMILY SSF63992 2 267 9.15E-79 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CNX65_RS17605 ac0e5b678bbd93946a54e965895aebc3 275 Gene3D G3DSA:3.40.50.10780 1 210 6.6E-79 T 28-03-2018 IPR027476 D-aminopeptidase, N-terminal CNX65_RS17605 ac0e5b678bbd93946a54e965895aebc3 275 Pfam PF04951 D-aminopeptidase 2 260 5.5E-88 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CNX65_RS17605 ac0e5b678bbd93946a54e965895aebc3 275 PIRSF PIRSF015853 1 272 9.4E-86 T 28-03-2018 IPR007035 Peptidase M55, D-aminopeptidase CNX65_RS14120 d80319ccb51b12961356e20d77a6d31a 189 Gene3D G3DSA:1.10.10.60 7 47 1.3E-15 T 28-03-2018 CNX65_RS14120 d80319ccb51b12961356e20d77a6d31a 189 Pfam PF00440 Bacterial regulatory proteins, tetR family 13 59 9.6E-15 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14120 d80319ccb51b12961356e20d77a6d31a 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 34 57 1.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14120 d80319ccb51b12961356e20d77a6d31a 189 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 13 26 1.8E-7 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS14120 d80319ccb51b12961356e20d77a6d31a 189 Gene3D G3DSA:1.10.10.60 48 174 5.2E-9 T 28-03-2018 CNX65_RS14120 d80319ccb51b12961356e20d77a6d31a 189 SUPERFAMILY SSF46689 7 76 2.96E-16 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS14655 47fdaa68c89dae6ef426238d3b778304 566 Gene3D G3DSA:3.40.50.10190 252 380 2.8E-6 T 28-03-2018 IPR001357 BRCT domain CNX65_RS15515 2463410576dfd244123cefcf8fb6e7ed 195 Gene3D G3DSA:2.160.20.10 4 190 4.0E-8 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS15515 2463410576dfd244123cefcf8fb6e7ed 195 SUPERFAMILY SSF51126 14 138 2.26E-11 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS22975 018cbfd8e6b8a3b1a5029fd2458139b2 149 Pfam PF03780 Asp23 family, cell envelope-related function 21 132 4.1E-32 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CNX65_RS10935 4142f2865a22e531bde7073bf7698d62 182 SUPERFAMILY SSF53448 10 178 2.7E-24 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS10935 4142f2865a22e531bde7073bf7698d62 182 Gene3D G3DSA:3.90.550.10 4 180 3.8E-21 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS10935 4142f2865a22e531bde7073bf7698d62 182 Pfam PF12804 MobA-like NTP transferase domain 11 157 3.7E-26 T 28-03-2018 IPR025877 MobA-like NTP transferase CNX65_RS03880 dce9d31e41bf14f77e3ca6a031d32b71 260 Gene3D G3DSA:1.10.12.10 214 260 6.0E-15 T 28-03-2018 IPR014748 Crontonase, C-terminal CNX65_RS03880 dce9d31e41bf14f77e3ca6a031d32b71 260 SUPERFAMILY SSF52096 3 260 4.98E-84 T 28-03-2018 IPR029045 ClpP/crotonase-like domain CNX65_RS03880 dce9d31e41bf14f77e3ca6a031d32b71 260 Gene3D G3DSA:3.90.226.10 2 213 2.7E-65 T 28-03-2018 CNX65_RS03880 dce9d31e41bf14f77e3ca6a031d32b71 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 259 1.7E-61 T 28-03-2018 IPR001753 Crotonase superfamily GO:0003824|GO:0008152 CNX65_RS11080 09a8969cc82e0e195380b8dc9a035267 324 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 114 302 1.5E-13 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS11080 09a8969cc82e0e195380b8dc9a035267 324 Gene3D G3DSA:1.10.3720.10 35 319 3.3E-39 T 28-03-2018 CNX65_RS11080 09a8969cc82e0e195380b8dc9a035267 324 SUPERFAMILY SSF161098 79 306 1.44E-47 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS29740 f6093607440e903a76b1513a7656eb32 117 Gene3D G3DSA:1.10.1220.10 1 53 6.3E-8 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CNX65_RS29740 f6093607440e903a76b1513a7656eb32 117 SUPERFAMILY SSF47598 1 45 4.78E-5 T 28-03-2018 IPR010985 Ribbon-helix-helix GO:0006355 CNX65_RS13325 0c13a095005e3994cd69da97b22eede3 288 Gene3D G3DSA:1.10.3720.10 40 282 2.4E-22 T 28-03-2018 CNX65_RS13325 0c13a095005e3994cd69da97b22eede3 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 98 270 8.1E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS13325 0c13a095005e3994cd69da97b22eede3 288 SUPERFAMILY SSF161098 83 264 1.13E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS28945 731e2cd7e6450a4fba7f5d56ff70ea8d 85 Pfam PF10939 Protein of unknown function (DUF2631) 4 65 1.4E-25 T 28-03-2018 IPR024341 Protein of unknown function DUF2631 CNX65_RS28945 731e2cd7e6450a4fba7f5d56ff70ea8d 85 ProDom PD069408 TRANSMEMBRANE MEMBRANE RV2876/MT2944.1 CGL2017/CG2211 ML1584 POSSIBLE P20 13 81 1.0E-9 T 28-03-2018 IPR024341 Protein of unknown function DUF2631 CNX65_RS30610 33ca35ae74483c54e7b936d8e8666469 256 Pfam PF14011 EspG family 9 249 1.2E-55 T 28-03-2018 IPR025734 EspG family CNX65_RS11445 6e9819478798a1c5caaa398d2fd132c5 327 Pfam PF13280 WYL domain 147 319 2.2E-29 T 28-03-2018 IPR026881 WYL domain CNX65_RS23730 e339d8654b78d0cf41f9a0fcaf1918a5 270 SUPERFAMILY SSF159713 50 245 4.18E-20 T 28-03-2018 CNX65_RS23730 e339d8654b78d0cf41f9a0fcaf1918a5 270 Pfam PF04016 Putative heavy-metal chelation 138 244 1.1E-10 T 28-03-2018 IPR007161 Putative heavy-metal chelation domain CNX65_RS23730 e339d8654b78d0cf41f9a0fcaf1918a5 270 Gene3D G3DSA:3.40.50.720 20 258 2.1E-4 T 28-03-2018 CNX65_RS06580 dd84a215ef13c2b6c628bb54ef7f94d4 749 Gene3D G3DSA:3.30.70.1230 4 195 0.0024 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS06580 dd84a215ef13c2b6c628bb54ef7f94d4 749 SUPERFAMILY SSF55073 5 141 2.67E-5 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS21045 3702204318d733a071397b5e69d0ac51 451 Pfam PF13434 L-lysine 6-monooxygenase (NADPH-requiring) 22 366 1.9E-91 T 28-03-2018 IPR025700 L-lysine 6-monooxygenase/L-ornithine 5-monooxygenase CNX65_RS21045 3702204318d733a071397b5e69d0ac51 451 Gene3D G3DSA:3.50.50.60 219 450 6.9E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21045 3702204318d733a071397b5e69d0ac51 451 Gene3D G3DSA:3.50.50.60 23 218 6.5E-14 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21045 3702204318d733a071397b5e69d0ac51 451 SUPERFAMILY SSF51905 92 252 3.64E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21045 3702204318d733a071397b5e69d0ac51 451 SUPERFAMILY SSF51905 19 62 3.64E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS21045 3702204318d733a071397b5e69d0ac51 451 SUPERFAMILY SSF51905 291 429 3.64E-21 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS10445 b5fc605b8734aa5c883e86af7fb7670b 135 SUPERFAMILY SSF50346 21 125 3.14E-18 T 28-03-2018 IPR011033 PRC-barrel-like CNX65_RS10445 b5fc605b8734aa5c883e86af7fb7670b 135 Gene3D G3DSA:3.90.50.10 18 131 1.1E-14 T 28-03-2018 CNX65_RS33770 012b7cd21a807b24e16e41dd5f7152dd 100 SUPERFAMILY SSF49478 24 77 3.41E-8 T 28-03-2018 CNX65_RS33770 012b7cd21a807b24e16e41dd5f7152dd 100 Gene3D G3DSA:2.60.40.10 17 98 1.3E-9 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS33770 012b7cd21a807b24e16e41dd5f7152dd 100 Pfam PF07210 Protein of unknown function (DUF1416) 6 99 9.3E-40 T 28-03-2018 IPR010814 Protein of unknown function DUF1416 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 SUPERFAMILY SSF51905 16 177 9.73E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 SUPERFAMILY SSF51905 281 369 9.73E-45 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 Pfam PF01494 FAD binding domain 16 357 3.1E-14 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 Gene3D G3DSA:3.50.50.60 10 381 4.1E-40 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 156 171 7.3E-19 T 28-03-2018 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 16 38 7.3E-19 T 28-03-2018 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 296 311 7.3E-19 T 28-03-2018 CNX65_RS19095 4be64698e3333d43db7b86a3eddb1c30 388 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 311 327 7.3E-19 T 28-03-2018 CNX65_RS15825 ee35c99824caf343c92098be57325073 259 Pfam PF08021 Siderophore-interacting FAD-binding domain 83 130 1.7E-6 T 28-03-2018 IPR013113 FAD-binding 9, siderophore-interacting CNX65_RS15825 ee35c99824caf343c92098be57325073 259 Gene3D G3DSA:2.40.30.10 28 131 4.7E-15 T 28-03-2018 CNX65_RS15825 ee35c99824caf343c92098be57325073 259 Gene3D G3DSA:3.40.50.80 132 258 4.2E-10 T 28-03-2018 CNX65_RS15825 ee35c99824caf343c92098be57325073 259 SUPERFAMILY SSF63380 16 134 3.71E-10 T 28-03-2018 IPR017938 Riboflavin synthase-like beta-barrel GO:0016491|GO:0055114 CNX65_RS02350 5611948c776f1281ffe699a4fa6b5f3a 747 Pfam PF13625 Helicase conserved C-terminal domain 462 584 2.8E-39 T 28-03-2018 IPR032830 Helicase XPB/Ssl2, N-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 CNX65_RS15590 5a00920efdc399ec1a40760b4794e79b 269 SUPERFAMILY SSF52540 5 246 2.72E-43 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS15590 5a00920efdc399ec1a40760b4794e79b 269 SMART SM00382 37 225 1.2E-11 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS15590 5a00920efdc399ec1a40760b4794e79b 269 Gene3D G3DSA:3.40.50.300 1 257 1.8E-47 T 28-03-2018 CNX65_RS15590 5a00920efdc399ec1a40760b4794e79b 269 Pfam PF00005 ABC transporter 29 176 3.0E-19 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS31575 fe57911b3724ce500b30a21c0a24a795 57 Pfam PF04149 Domain of unknown function (DUF397) 4 49 6.5E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS24905 0967c4563f0946aed9c752d2beeb6073 271 SMART SM00382 28 217 7.4E-14 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS24905 0967c4563f0946aed9c752d2beeb6073 271 SUPERFAMILY SSF52540 5 233 5.33E-55 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS24905 0967c4563f0946aed9c752d2beeb6073 271 Gene3D G3DSA:3.40.50.300 2 238 2.2E-55 T 28-03-2018 CNX65_RS24905 0967c4563f0946aed9c752d2beeb6073 271 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 28-03-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 CNX65_RS24905 0967c4563f0946aed9c752d2beeb6073 271 Pfam PF00005 ABC transporter 21 167 2.6E-30 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS00635 4393ac6d2125f59f0bf731e0876edd71 432 Pfam PF01757 Acyltransferase family 41 411 5.4E-24 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS34195 972bb251c318ce96a82668f4d3f9dc3a 95 Gene3D G3DSA:3.30.70.1060 1 88 4.7E-23 T 28-03-2018 CNX65_RS34195 972bb251c318ce96a82668f4d3f9dc3a 95 Pfam PF03795 YCII-related domain 10 85 4.4E-16 T 28-03-2018 IPR005545 YCII-related CNX65_RS34195 972bb251c318ce96a82668f4d3f9dc3a 95 SUPERFAMILY SSF54909 1 86 3.93E-23 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS18425 9613e4d391c2bd30c75bef4c6435b79e 182 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 129 163 2.5E-9 T 28-03-2018 IPR001451 Hexapeptide repeat CNX65_RS18425 9613e4d391c2bd30c75bef4c6435b79e 182 Gene3D G3DSA:2.160.10.10 8 182 8.6E-36 T 28-03-2018 CNX65_RS18425 9613e4d391c2bd30c75bef4c6435b79e 182 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 137 165 - T 28-03-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 CNX65_RS18425 9613e4d391c2bd30c75bef4c6435b79e 182 SUPERFAMILY SSF51161 52 182 1.66E-36 T 28-03-2018 IPR011004 Trimeric LpxA-like CNX65_RS25665 a3aeb4d1ebaaa5bc63b05ce6965832f9 388 SUPERFAMILY SSF53756 2 376 2.0E-82 T 28-03-2018 CNX65_RS25665 a3aeb4d1ebaaa5bc63b05ce6965832f9 388 Pfam PF13579 Glycosyl transferase 4-like domain 16 182 1.1E-20 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS25665 a3aeb4d1ebaaa5bc63b05ce6965832f9 388 Pfam PF00534 Glycosyl transferases group 1 190 350 3.1E-32 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS25665 a3aeb4d1ebaaa5bc63b05ce6965832f9 388 Gene3D G3DSA:3.40.50.2000 1 195 4.2E-19 T 28-03-2018 CNX65_RS25665 a3aeb4d1ebaaa5bc63b05ce6965832f9 388 Gene3D G3DSA:3.40.50.2000 196 352 3.3E-47 T 28-03-2018 CNX65_RS04285 108ebc470648e1020e49d348a4956c82 187 Gene3D G3DSA:3.40.50.1010 2 133 2.4E-6 T 28-03-2018 IPR029060 PIN domain-like CNX65_RS11725 4713115c4d87a5be2fdb5109ce7beca7 174 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 64 168 2.1E-18 T 28-03-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 CNX65_RS11725 4713115c4d87a5be2fdb5109ce7beca7 174 Gene3D G3DSA:3.30.750.24 60 174 2.5E-17 T 28-03-2018 IPR002645 STAS domain CNX65_RS11725 4713115c4d87a5be2fdb5109ce7beca7 174 Pfam PF13466 STAS domain 77 159 5.8E-14 T 28-03-2018 IPR002645 STAS domain CNX65_RS11725 4713115c4d87a5be2fdb5109ce7beca7 174 SUPERFAMILY SSF52091 64 173 4.51E-18 T 28-03-2018 IPR002645 STAS domain CNX65_RS13115 696f89b143aa5a13ec1923502b206834 175 SUPERFAMILY SSF160424 36 166 1.01E-24 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS09245 c35c369cccf7f4feeebd326e091dcb4e 130 Gene3D G3DSA:3.10.180.10 1 130 1.1E-15 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS09245 c35c369cccf7f4feeebd326e091dcb4e 130 SUPERFAMILY SSF54593 8 128 1.93E-14 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS17575 a92d04835c01ec76d892e1f898ddd3a8 188 Pfam PF11066 Protein of unknown function (DUF2867) 19 173 1.7E-24 T 28-03-2018 IPR021295 Protein of unknown function DUF2867 CNX65_RS31870 84aa8562658535ac4226c9ca99c248d0 507 SUPERFAMILY SSF160424 14 142 1.11E-13 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS31870 84aa8562658535ac4226c9ca99c248d0 507 Pfam PF14021 Tuberculosis necrotizing toxin 412 497 6.6E-23 T 28-03-2018 IPR025331 Tuberculosis necrotizing toxin CNX65_RS09685 979f45c0118ef1a35abd5e10d3502a5a 242 Pfam PF12698 ABC-2 family transporter protein 54 234 4.0E-11 T 28-03-2018 CNX65_RS06045 2f98c2fe6eac168e9171e540b1d63f1d 553 PIRSF PIRSF005522 32 509 1.5E-213 T 28-03-2018 IPR016450 Uncharacterised conserved protein UCP005522 CNX65_RS06045 2f98c2fe6eac168e9171e540b1d63f1d 553 Gene3D G3DSA:3.30.470.20 364 544 1.7E-4 T 28-03-2018 CNX65_RS06045 2f98c2fe6eac168e9171e540b1d63f1d 553 SUPERFAMILY SSF56059 54 244 4.71E-56 T 28-03-2018 CNX65_RS06045 2f98c2fe6eac168e9171e540b1d63f1d 553 SUPERFAMILY SSF56059 351 497 4.71E-56 T 28-03-2018 CNX65_RS06045 2f98c2fe6eac168e9171e540b1d63f1d 553 Pfam PF14403 Circularly permuted ATP-grasp type 2 106 482 5.9E-161 T 28-03-2018 IPR025841 Circularly permuted ATP-grasp type 2 CNX65_RS17365 fe786f57bd0e6519e3d802a7833f738b 190 Pfam PF01758 Sodium Bile acid symporter family 50 93 6.3E-6 T 28-03-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 CNX65_RS07665 8041285bc9908164bee3a5fa18d7b45d 149 Pfam PF14108 Domain of unknown function (DUF4281) 5 129 1.0E-31 T 28-03-2018 IPR025461 ABA DEFICIENT 4-like CNX65_RS12555 731e1f9eebb915153d09649909827e18 205 Gene3D G3DSA:3.40.50.850 1 187 1.2E-47 T 28-03-2018 CNX65_RS12555 731e1f9eebb915153d09649909827e18 205 SUPERFAMILY SSF52499 6 204 8.63E-50 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS12555 731e1f9eebb915153d09649909827e18 205 Pfam PF00857 Isochorismatase family 12 189 1.7E-42 T 28-03-2018 IPR000868 Isochorismatase-like GO:0003824|GO:0008152 CNX65_RS14855 89e75c5c7952731e0b1246bbd7b34fdc 335 Gene3D G3DSA:2.60.120.260 187 334 6.5E-7 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS14855 89e75c5c7952731e0b1246bbd7b34fdc 335 Gene3D G3DSA:2.20.28.20 108 138 3.0E-4 T 28-03-2018 CNX65_RS24365 d82cb4cfb467b447740f16c33fa4de2f 309 Pfam PF00106 short chain dehydrogenase 43 169 2.6E-12 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24365 d82cb4cfb467b447740f16c33fa4de2f 309 SUPERFAMILY SSF51735 39 281 1.54E-39 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS24365 d82cb4cfb467b447740f16c33fa4de2f 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 113 124 6.4E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24365 d82cb4cfb467b447740f16c33fa4de2f 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 242 262 6.4E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24365 d82cb4cfb467b447740f16c33fa4de2f 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 214 231 6.4E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24365 d82cb4cfb467b447740f16c33fa4de2f 309 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 43 60 6.4E-13 T 28-03-2018 IPR002347 Short-chain dehydrogenase/reductase SDR CNX65_RS24365 d82cb4cfb467b447740f16c33fa4de2f 309 Gene3D G3DSA:3.40.50.720 32 308 2.9E-45 T 28-03-2018 CNX65_RS00210 2c17a37af8cf7bb474b4a2ad71a51a07 298 Gene3D G3DSA:1.10.510.10 56 284 5.8E-18 T 28-03-2018 CNX65_RS00210 2c17a37af8cf7bb474b4a2ad71a51a07 298 SUPERFAMILY SSF56112 7 262 5.98E-31 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS00210 2c17a37af8cf7bb474b4a2ad71a51a07 298 Pfam PF01636 Phosphotransferase enzyme family 48 236 3.2E-16 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS25750 449ebef76ddf899e9eb5625b18b29441 543 Pfam PF05960 Bacterial protein of unknown function (DUF885) 31 539 2.7E-102 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CNX65_RS26270 00e08b63159cec8cce65b1673288dd8b 116 Pfam PF04341 Protein of unknown function, DUF485 34 106 3.1E-8 T 28-03-2018 IPR007436 Protein of unknown function DUF485 CNX65_RS07870 acb2e56a1b987555932c789d2df80bc3 461 Pfam PF10009 Uncharacterized protein conserved in bacteria (DUF2252) 61 447 4.5E-137 T 28-03-2018 IPR018721 Protein of unknown function DUF2252 CNX65_RS05185 3cd3cbc3bfaf489f6bb093333fefeb64 235 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 6 198 3.9E-33 T 28-03-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 CNX65_RS05185 3cd3cbc3bfaf489f6bb093333fefeb64 235 Gene3D G3DSA:3.40.50.880 1 233 1.8E-21 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS05185 3cd3cbc3bfaf489f6bb093333fefeb64 235 SUPERFAMILY SSF52317 17 213 1.09E-21 T 28-03-2018 IPR029062 Class I glutamine amidotransferase-like CNX65_RS17560 89ba50653450452548aa1dbeae5691ec 344 Pfam PF01636 Phosphotransferase enzyme family 25 242 5.9E-47 T 28-03-2018 IPR002575 Aminoglycoside phosphotransferase CNX65_RS17560 89ba50653450452548aa1dbeae5691ec 344 Gene3D G3DSA:3.30.200.20 10 101 8.2E-25 T 28-03-2018 CNX65_RS17560 89ba50653450452548aa1dbeae5691ec 344 Gene3D G3DSA:3.90.1200.10 102 292 3.9E-32 T 28-03-2018 CNX65_RS17560 89ba50653450452548aa1dbeae5691ec 344 SUPERFAMILY SSF56112 20 307 5.98E-57 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS23505 3ea4fd4b8c4bb052715115f936e1d4f6 333 Gene3D G3DSA:3.10.310.10 1 151 3.6E-38 T 28-03-2018 CNX65_RS23505 3ea4fd4b8c4bb052715115f936e1d4f6 333 Gene3D G3DSA:3.10.310.10 152 309 5.8E-54 T 28-03-2018 CNX65_RS23505 3ea4fd4b8c4bb052715115f936e1d4f6 333 Pfam PF05544 Proline racemase 10 331 3.7E-128 T 28-03-2018 IPR008794 Proline racemase family CNX65_RS23505 3ea4fd4b8c4bb052715115f936e1d4f6 333 PIRSF PIRSF029792 1 333 2.1E-129 T 28-03-2018 IPR008794 Proline racemase family CNX65_RS23505 3ea4fd4b8c4bb052715115f936e1d4f6 333 SUPERFAMILY SSF54506 2 331 7.99E-115 T 28-03-2018 CNX65_RS25345 2d82540ff5421f8fe80d51cc859a457a 129 Pfam PF00965 Tissue inhibitor of metalloproteinase 25 123 6.4E-6 T 28-03-2018 IPR001820 Protease inhibitor I35 (TIMP) GO:0008191 CNX65_RS25345 2d82540ff5421f8fe80d51cc859a457a 129 SUPERFAMILY SSF50242 26 128 3.14E-16 T 28-03-2018 IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold CNX65_RS25345 2d82540ff5421f8fe80d51cc859a457a 129 Gene3D G3DSA:2.40.50.120 41 128 7.6E-14 T 28-03-2018 CNX65_RS31840 1611d3c13e62ad69eb82278feb0a7399 63 SUPERFAMILY SSF50118 1 61 7.85E-24 T 28-03-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor CNX65_RS31840 1611d3c13e62ad69eb82278feb0a7399 63 Pfam PF08940 Domain of unknown function (DUF1918) 1 57 5.8E-29 T 28-03-2018 IPR015035 Domain of unknown function DUF1918 CNX65_RS02880 4f0f4a95457a758045f6098963fd582e 294 Pfam PF13560 Helix-turn-helix domain 24 84 3.2E-11 T 28-03-2018 CNX65_RS02880 4f0f4a95457a758045f6098963fd582e 294 Gene3D G3DSA:1.10.260.40 23 274 6.0E-10 T 28-03-2018 CNX65_RS31985 d832fd98d2a986eae790b2dcf9884ea5 299 Gene3D G3DSA:2.130.10.10 44 244 1.1E-4 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS25620 928f376f01da45299d8f976e66c9392e 257 SUPERFAMILY SSF52540 4 234 1.14E-40 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS25620 928f376f01da45299d8f976e66c9392e 257 SMART SM00382 32 233 3.4E-6 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS25620 928f376f01da45299d8f976e66c9392e 257 Gene3D G3DSA:3.40.50.300 1 255 1.5E-41 T 28-03-2018 CNX65_RS25620 928f376f01da45299d8f976e66c9392e 257 Pfam PF00005 ABC transporter 23 174 4.6E-21 T 28-03-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 CNX65_RS25620 928f376f01da45299d8f976e66c9392e 257 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 246 5.3E-104 T 28-03-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524|GO:0006810 CNX65_RS16235 b725777326b914110b9df5eb64d8138e 115 Gene3D G3DSA:3.30.70.1060 1 115 4.2E-30 T 28-03-2018 CNX65_RS16235 b725777326b914110b9df5eb64d8138e 115 SUPERFAMILY SSF54909 2 113 3.7E-25 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS16235 b725777326b914110b9df5eb64d8138e 115 Pfam PF03795 YCII-related domain 2 111 1.0E-10 T 28-03-2018 IPR005545 YCII-related CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00385 P450 superfamily signature 238 255 1.8E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00385 P450 superfamily signature 273 284 1.8E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00385 P450 superfamily signature 340 349 1.8E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00385 P450 superfamily signature 349 360 1.8E-9 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 291 318 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 91 102 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 273 284 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 319 334 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 138 154 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 155 170 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 340 349 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 349 360 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 PRINTS PR00359 B-class P450 signature 192 214 1.3E-53 T 28-03-2018 IPR002397 Cytochrome P450, B-class GO:0005506|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 SUPERFAMILY SSF48264 16 400 8.91E-90 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 Gene3D G3DSA:1.10.630.10 12 400 9.8E-71 T 28-03-2018 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 ProSitePatterns PS00086 Cytochrome P450 cysteine heme-iron ligand signature. 342 351 - T 28-03-2018 IPR017972 Cytochrome P450, conserved site GO:0016705|GO:0055114 CNX65_RS13255 7f02e96c8bc1c77dcf734285fe83ea78 400 Pfam PF00067 Cytochrome P450 209 369 6.2E-27 T 28-03-2018 IPR001128 Cytochrome P450 GO:0005506|GO:0016705|GO:0020037|GO:0055114 CNX65_RS21330 f888b14d5bbe5c37bfd38094c17c17d5 425 Gene3D G3DSA:3.30.470.20 155 196 1.0E-4 T 28-03-2018 CNX65_RS21330 f888b14d5bbe5c37bfd38094c17c17d5 425 Gene3D G3DSA:3.40.50.20 36 154 2.3E-17 T 28-03-2018 CNX65_RS21330 f888b14d5bbe5c37bfd38094c17c17d5 425 SUPERFAMILY SSF56059 133 322 3.74E-16 T 28-03-2018 CNX65_RS21330 f888b14d5bbe5c37bfd38094c17c17d5 425 Gene3D G3DSA:3.30.470.20 210 348 2.0E-10 T 28-03-2018 CNX65_RS30170 6d292fe3e2de1d4987c58dd8417199da 225 Pfam PF12079 Protein of unknown function (DUF3558) 66 222 3.2E-9 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS34665 5c621c7c23862d7b62b478056fd3ad88 388 SUPERFAMILY SSF55874 265 384 1.08E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34665 5c621c7c23862d7b62b478056fd3ad88 388 SMART SM00387 293 387 3.6E-4 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34665 5c621c7c23862d7b62b478056fd3ad88 388 Pfam PF07730 Histidine kinase 192 253 7.5E-13 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS34665 5c621c7c23862d7b62b478056fd3ad88 388 Gene3D G3DSA:3.30.565.10 182 386 1.4E-19 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS16800 a32c5e205250ee5ca66345c7ef4fcd27 85 Gene3D G3DSA:2.30.30.240 1 85 6.5E-8 T 28-03-2018 CNX65_RS14025 3b714fcb864704fbc9f129ba3d9a3c2b 181 Pfam PF07884 Vitamin K epoxide reductase family 11 139 6.2E-30 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CNX65_RS14025 3b714fcb864704fbc9f129ba3d9a3c2b 181 SMART SM00756 2 143 5.8E-48 T 28-03-2018 IPR012932 Vitamin K epoxide reductase Reactome: R-HSA-6806664 CNX65_RS11975 cdf9e923247f65664aa18e6d198ade90 132 Pfam PF02561 Flagellar protein FliS 9 119 4.1E-27 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CNX65_RS11975 cdf9e923247f65664aa18e6d198ade90 132 Gene3D G3DSA:1.20.120.340 1 122 2.3E-25 T 28-03-2018 CNX65_RS11975 cdf9e923247f65664aa18e6d198ade90 132 SUPERFAMILY SSF101116 6 120 1.83E-24 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CNX65_RS11975 cdf9e923247f65664aa18e6d198ade90 132 TIGRFAM TIGR00208 fliS: flagellar protein FliS 9 120 2.1E-17 T 28-03-2018 IPR003713 Flagellar protein FliS GO:0044780 CNX65_RS21645 c2dd9bcf8d39a4e84c4e4223e19aa396 280 SUPERFAMILY SSF161098 81 276 2.22E-21 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS21645 c2dd9bcf8d39a4e84c4e4223e19aa396 280 Gene3D G3DSA:1.10.3720.10 5 274 1.8E-37 T 28-03-2018 CNX65_RS21645 c2dd9bcf8d39a4e84c4e4223e19aa396 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 277 8.8E-26 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS02005 3c0a1602f709db81327992058db10163 110 Gene3D G3DSA:1.10.10.10 10 106 4.1E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS33660 2e34e9eb44ecf9a9afb15b5e06be18eb 155 Pfam PF14232 Domain of unknown function (DUF4334) 96 154 2.7E-26 T 28-03-2018 IPR025568 Domain of unknown function DUF4334 CNX65_RS33660 2e34e9eb44ecf9a9afb15b5e06be18eb 155 Pfam PF14231 GXWXG protein 27 85 7.9E-25 T 28-03-2018 IPR025951 GXWXG domain CNX65_RS12085 9d242d7274ea8f02b7dda42dc6e8a698 174 SMART SM00754 60 174 4.2E-19 T 28-03-2018 IPR010895 CHRD CNX65_RS12085 9d242d7274ea8f02b7dda42dc6e8a698 174 Pfam PF07452 CHRD domain 64 172 1.8E-21 T 28-03-2018 IPR010895 CHRD CNX65_RS14430 1bf0ab66dd7ec14badf8f2862de268f6 245 Gene3D G3DSA:3.10.180.10 12 143 1.7E-11 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS14430 1bf0ab66dd7ec14badf8f2862de268f6 245 SUPERFAMILY SSF54593 13 132 2.23E-12 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS33085 2ed99ca6837c9192a62780e307b5c369 258 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 19 235 6.5E-42 T 28-03-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 CNX65_RS20440 e15d486b4ab3ba72174023d55c0a0181 152 Gene3D G3DSA:3.10.129.10 1 145 2.8E-23 T 28-03-2018 CNX65_RS20440 e15d486b4ab3ba72174023d55c0a0181 152 Pfam PF13279 Thioesterase-like superfamily 11 135 3.8E-8 T 28-03-2018 CNX65_RS20440 e15d486b4ab3ba72174023d55c0a0181 152 SUPERFAMILY SSF54637 4 139 1.34E-25 T 28-03-2018 IPR029069 HotDog domain CNX65_RS19160 0e234e3797a432bdc3d886c63cc03684 186 SUPERFAMILY SSF53335 47 140 8.98E-5 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS17660 9a9fff87ed9b1da6102a195dae3e4487 269 SUPERFAMILY SSF53474 8 183 4.42E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17660 9a9fff87ed9b1da6102a195dae3e4487 269 SUPERFAMILY SSF53474 224 241 4.42E-23 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS17660 9a9fff87ed9b1da6102a195dae3e4487 269 Gene3D G3DSA:3.40.50.1820 5 268 4.5E-27 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS31105 fd99cd8a286c72ad2d3dfd06695564df 503 PIRSF PIRSF006060 8 500 6.1E-91 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS31105 fd99cd8a286c72ad2d3dfd06695564df 503 Pfam PF13520 Amino acid permease 31 458 3.3E-50 T 28-03-2018 IPR002293 Amino acid/polyamine transporter I GO:0003333|GO:0015171|GO:0016020 CNX65_RS05245 01c9f39de6eb76bf453f5eede83b3e41 575 Gene3D G3DSA:2.40.110.10 141 244 5.9E-12 T 28-03-2018 CNX65_RS05245 01c9f39de6eb76bf453f5eede83b3e41 575 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 250 397 2.4E-19 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS05245 01c9f39de6eb76bf453f5eede83b3e41 575 Gene3D G3DSA:1.10.540.10 12 133 6.4E-5 T 28-03-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 CNX65_RS05245 01c9f39de6eb76bf453f5eede83b3e41 575 SUPERFAMILY SSF56645 21 244 1.07E-25 T 28-03-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain GO:0008152|GO:0016627|GO:0055114 CNX65_RS05245 01c9f39de6eb76bf453f5eede83b3e41 575 SUPERFAMILY SSF47203 249 403 7.25E-29 T 28-03-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 CNX65_RS05245 01c9f39de6eb76bf453f5eede83b3e41 575 Gene3D G3DSA:1.20.140.10 245 401 3.7E-22 T 28-03-2018 CNX65_RS02835 da8a5346606c41336fde62a678c5a783 462 SUPERFAMILY SSF52540 27 204 2.55E-7 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS02835 da8a5346606c41336fde62a678c5a783 462 Gene3D G3DSA:3.40.50.300 30 427 1.9E-7 T 28-03-2018 CNX65_RS30345 a89774080739eace0b120b20c5966bd2 615 Pfam PF00150 Cellulase (glycosyl hydrolase family 5) 49 380 7.4E-12 T 28-03-2018 IPR001547 Glycoside hydrolase, family 5 GO:0004553|GO:0005975 CNX65_RS30345 a89774080739eace0b120b20c5966bd2 615 SUPERFAMILY SSF51445 214 419 1.23E-29 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS30345 a89774080739eace0b120b20c5966bd2 615 SUPERFAMILY SSF51445 6 155 1.23E-29 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS30345 a89774080739eace0b120b20c5966bd2 615 Gene3D G3DSA:3.20.20.80 37 452 2.5E-30 T 28-03-2018 CNX65_RS15530 046d54277fa78b96c6d86fabc260a23e 112 Pfam PF02656 Domain of unknown function (DUF202) 8 73 1.1E-8 T 28-03-2018 IPR003807 Domain of unknown function DUF202 CNX65_RS16000 41435574d93f676d42f3d6ddbbdd5cab 230 Gene3D G3DSA:1.10.10.60 23 83 3.7E-16 T 28-03-2018 CNX65_RS16000 41435574d93f676d42f3d6ddbbdd5cab 230 Gene3D G3DSA:1.10.357.10 84 222 1.5E-23 T 28-03-2018 CNX65_RS16000 41435574d93f676d42f3d6ddbbdd5cab 230 SUPERFAMILY SSF46689 30 110 7.98E-14 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS16000 41435574d93f676d42f3d6ddbbdd5cab 230 Pfam PF00440 Bacterial regulatory proteins, tetR family 44 82 1.2E-11 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS17240 077cd102628910dd1402be183196a21d 263 Gene3D G3DSA:3.90.550.10 2 259 3.7E-39 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS17240 077cd102628910dd1402be183196a21d 263 SUPERFAMILY SSF53448 14 227 1.02E-43 T 28-03-2018 IPR029044 Nucleotide-diphospho-sugar transferases CNX65_RS17240 077cd102628910dd1402be183196a21d 263 Pfam PF00535 Glycosyl transferase family 2 17 180 4.3E-30 T 28-03-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 CNX65_RS06020 98e1797c047cfa98598d496465446e3f 267 Pfam PF01925 Sulfite exporter TauE/SafE 22 260 1.4E-34 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CNX65_RS24670 b0b2944f87fb33cfacb201f454b26acc 185 Pfam PF13302 Acetyltransferase (GNAT) domain 11 151 2.9E-35 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS24670 b0b2944f87fb33cfacb201f454b26acc 185 Gene3D G3DSA:3.40.630.30 2 183 8.4E-39 T 28-03-2018 CNX65_RS24670 b0b2944f87fb33cfacb201f454b26acc 185 SUPERFAMILY SSF55729 5 175 3.48E-47 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS04280 a5cf12992292e4d5d9b2c7e97e5d1c30 359 Gene3D G3DSA:1.10.260.40 4 72 2.5E-14 T 28-03-2018 CNX65_RS04280 a5cf12992292e4d5d9b2c7e97e5d1c30 359 SUPERFAMILY SSF47413 4 67 3.49E-13 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS04280 a5cf12992292e4d5d9b2c7e97e5d1c30 359 SMART SM00530 9 64 2.4E-10 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS04280 a5cf12992292e4d5d9b2c7e97e5d1c30 359 Pfam PF06114 IrrE N-terminal-like domain 182 267 4.9E-12 T 28-03-2018 IPR010359 IrrE N-terminal-like domain CNX65_RS04280 a5cf12992292e4d5d9b2c7e97e5d1c30 359 Pfam PF13560 Helix-turn-helix domain 6 61 5.2E-9 T 28-03-2018 CNX65_RS06080 9da156c6191266e889c2f2cca535eb6c 143 Pfam PF13328 HD domain 8 109 3.0E-8 T 28-03-2018 IPR003607 HD/PDEase domain CNX65_RS06080 9da156c6191266e889c2f2cca535eb6c 143 SUPERFAMILY SSF109604 5 134 7.63E-24 T 28-03-2018 CNX65_RS29620 05a548e8bd291fe0a7facc2c4dc619d4 217 ProDom PD072817 ANTIGEN WEIGHT MOLECULAR LOW CFP-6 CGL1269 SEQUENCING DIRECT 31 138 1.0E-9 T 28-03-2018 IPR020535 Low molecular weight antigen Cfp6 CNX65_RS29620 05a548e8bd291fe0a7facc2c4dc619d4 217 Pfam PF10756 Bacterial PH domain 68 137 3.4E-10 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CNX65_RS04810 16c2413508659f264b4c82510dd98071 374 TIGRFAM TIGR03187 DGQHR: DGQHR domain 11 303 4.6E-68 T 28-03-2018 IPR017601 DGQHR-containing domain CNX65_RS04810 16c2413508659f264b4c82510dd98071 374 Pfam PF14072 DNA-sulfur modification-associated 9 365 5.1E-40 T 28-03-2018 IPR017642 DNA sulphur modification protein DndB CNX65_RS09455 1962cc7c6efbfe26aaa847a2c90db8ca 160 Pfam PF14325 Domain of unknown function (DUF4383) 8 131 5.2E-41 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CNX65_RS18920 cd6046873cf6c13a8cfa5fb7406d5422 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 38 61 2.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18920 cd6046873cf6c13a8cfa5fb7406d5422 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 17 30 2.7E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS18920 cd6046873cf6c13a8cfa5fb7406d5422 216 Gene3D G3DSA:1.10.10.60 3 38 5.6E-15 T 28-03-2018 CNX65_RS18920 cd6046873cf6c13a8cfa5fb7406d5422 216 Gene3D G3DSA:1.10.260.40 39 73 1.8E-13 T 28-03-2018 CNX65_RS18920 cd6046873cf6c13a8cfa5fb7406d5422 216 Gene3D G3DSA:1.10.357.10 74 215 7.1E-11 T 28-03-2018 CNX65_RS18920 cd6046873cf6c13a8cfa5fb7406d5422 216 SUPERFAMILY SSF46689 7 80 4.09E-17 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS18920 cd6046873cf6c13a8cfa5fb7406d5422 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 17 62 1.2E-14 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS34605 95c4cf3ed5574a1b28ab7b0d4ed7c634 81 Pfam PF04149 Domain of unknown function (DUF397) 27 78 3.1E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS34605 95c4cf3ed5574a1b28ab7b0d4ed7c634 81 Pfam PF04149 Domain of unknown function (DUF397) 6 25 4.1E-6 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS12570 67d7fa695a5df2676f2be715b975b7db 236 Pfam PF13490 Putative zinc-finger 3 37 9.0E-8 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS11195 f4f49ff209f64e25012f09268dda4f32 156 PRINTS PR00502 NUDIX hydrolase family signature 61 76 6.9E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS11195 f4f49ff209f64e25012f09268dda4f32 156 PRINTS PR00502 NUDIX hydrolase family signature 47 61 6.9E-5 T 28-03-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 CNX65_RS11195 f4f49ff209f64e25012f09268dda4f32 156 SUPERFAMILY SSF55811 26 134 3.93E-23 T 28-03-2018 IPR015797 NUDIX hydrolase domain-like GO:0016787 CNX65_RS11195 f4f49ff209f64e25012f09268dda4f32 156 ProSitePatterns PS00893 Nudix box signature. 52 73 - T 28-03-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 CNX65_RS11195 f4f49ff209f64e25012f09268dda4f32 156 Pfam PF00293 NUDIX domain 29 131 5.4E-16 T 28-03-2018 IPR000086 NUDIX hydrolase domain GO:0016787 CNX65_RS11195 f4f49ff209f64e25012f09268dda4f32 156 Gene3D G3DSA:3.90.79.10 2 141 7.0E-23 T 28-03-2018 CNX65_RS08065 96df403f2a3e08c0b76ffd824e135132 348 SUPERFAMILY SSF51735 4 315 1.25E-61 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS08065 96df403f2a3e08c0b76ffd824e135132 348 Gene3D G3DSA:3.40.50.720 2 315 7.8E-47 T 28-03-2018 CNX65_RS08065 96df403f2a3e08c0b76ffd824e135132 348 Pfam PF01370 NAD dependent epimerase/dehydratase family 5 224 8.5E-30 T 28-03-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 CNX65_RS04885 ea7ad8af9cdf9304874c1c88d28290c8 276 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 268 8.1E-22 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS04885 ea7ad8af9cdf9304874c1c88d28290c8 276 Gene3D G3DSA:1.10.3720.10 2 263 5.0E-43 T 28-03-2018 CNX65_RS04885 ea7ad8af9cdf9304874c1c88d28290c8 276 SUPERFAMILY SSF161098 4 276 2.62E-72 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS12620 c4e1cca9c0220eb30e1297e04d7f9830 219 Gene3D G3DSA:3.40.630.30 5 204 3.1E-11 T 28-03-2018 CNX65_RS12620 c4e1cca9c0220eb30e1297e04d7f9830 219 SUPERFAMILY SSF55729 101 185 1.28E-8 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS12620 c4e1cca9c0220eb30e1297e04d7f9830 219 Pfam PF00583 Acetyltransferase (GNAT) family 100 179 1.3E-4 T 28-03-2018 IPR000182 GNAT domain GO:0008080 CNX65_RS26950 319c31f1a2dc9370387d07155df21970 203 Gene3D G3DSA:1.10.1740.10 4 103 1.5E-19 T 28-03-2018 CNX65_RS26950 319c31f1a2dc9370387d07155df21970 203 Gene3D G3DSA:1.10.10.10 104 181 1.9E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26950 319c31f1a2dc9370387d07155df21970 203 SUPERFAMILY SSF88659 108 178 2.83E-6 T 28-03-2018 IPR013324 RNA polymerase sigma factor, region 3/4 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26950 319c31f1a2dc9370387d07155df21970 203 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 21 177 7.3E-19 T 28-03-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26950 319c31f1a2dc9370387d07155df21970 203 Pfam PF04542 Sigma-70 region 2 25 92 2.1E-12 T 28-03-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS26950 319c31f1a2dc9370387d07155df21970 203 SUPERFAMILY SSF88946 6 106 2.2E-20 T 28-03-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 CNX65_RS12390 9da2f694c56392d152fcccd1cf2fcb4b 275 SMART SM00530 9 81 3.2E-7 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS12390 9da2f694c56392d152fcccd1cf2fcb4b 275 Pfam PF13560 Helix-turn-helix domain 5 84 1.0E-17 T 28-03-2018 CNX65_RS12390 9da2f694c56392d152fcccd1cf2fcb4b 275 SUPERFAMILY SSF47413 30 80 1.81E-8 T 28-03-2018 IPR010982 Lambda repressor-like, DNA-binding domain GO:0003677 CNX65_RS12390 9da2f694c56392d152fcccd1cf2fcb4b 275 Gene3D G3DSA:1.10.260.40 1 86 4.7E-16 T 28-03-2018 CNX65_RS22455 94d45811855826513930d946dfebe5df 222 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 217 1.9E-19 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS22455 94d45811855826513930d946dfebe5df 222 Gene3D G3DSA:1.10.10.10 122 221 1.3E-28 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS22455 94d45811855826513930d946dfebe5df 222 SMART SM00448 1 112 1.5E-29 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS22455 94d45811855826513930d946dfebe5df 222 SMART SM00862 145 217 5.5E-22 T 28-03-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 CNX65_RS22455 94d45811855826513930d946dfebe5df 222 Gene3D G3DSA:3.40.50.2300 1 121 9.6E-29 T 28-03-2018 CNX65_RS22455 94d45811855826513930d946dfebe5df 222 Pfam PF00072 Response regulator receiver domain 3 112 2.4E-21 T 28-03-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 CNX65_RS22455 94d45811855826513930d946dfebe5df 222 SUPERFAMILY SSF52172 2 172 5.28E-34 T 28-03-2018 IPR011006 CheY-like superfamily CNX65_RS17510 85b5767b9b1afa6cd0c4b9be7c9dfa41 267 TIGRFAM TIGR03843 TIGR03843: conserved hypothetical protein 13 267 7.2E-111 T 28-03-2018 IPR022292 Conserved hypothetical protein CHP03843 CNX65_RS10865 92fbdffb810a32fd82abe90d7b34819a 127 Gene3D G3DSA:1.20.141.10 6 91 7.5E-6 T 28-03-2018 CNX65_RS10865 92fbdffb810a32fd82abe90d7b34819a 127 Gene3D G3DSA:1.20.141.10 92 121 0.21 T 28-03-2018 CNX65_RS10865 92fbdffb810a32fd82abe90d7b34819a 127 SUPERFAMILY SSF47090 45 120 9.16E-8 T 28-03-2018 IPR002477 Peptidoglycan binding-like CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 SUPERFAMILY SSF53474 2 255 3.19E-34 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 Gene3D G3DSA:3.40.50.1820 1 261 5.8E-32 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 Pfam PF12697 Alpha/beta hydrolase family 12 246 3.8E-12 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 PRINTS PR00412 Epoxide hydrolase signature 81 94 4.7E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 PRINTS PR00412 Epoxide hydrolase signature 231 253 4.7E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 PRINTS PR00412 Epoxide hydrolase signature 198 214 4.7E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 PRINTS PR00412 Epoxide hydrolase signature 37 52 4.7E-6 T 28-03-2018 IPR000639 Epoxide hydrolase-like GO:0003824 CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 81 94 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS16785 258592fdec76fa50c0a274c53eb0af46 265 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 1.5E-5 T 28-03-2018 IPR000073 Alpha/beta hydrolase fold-1 CNX65_RS03700 6f0c35eb5e9ee31dd7459174f478fce5 288 Pfam PF12679 ABC-2 family transporter protein 88 282 1.4E-12 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CNX65_RS04925 899615579edb0c3285c055e5acf623ad 266 Gene3D G3DSA:3.90.1720.10 63 206 1.1E-4 T 28-03-2018 CNX65_RS25580 619d26c71caca9da319eb86d4c7418ff 449 Pfam PF05231 MASE1 29 305 3.0E-37 T 28-03-2018 IPR007895 MASE1 CNX65_RS10090 6029be67eda9f61a6b413d0fdeefee37 139 Pfam PF09656 Putative transmembrane protein (PGPGW) 27 78 5.1E-23 T 28-03-2018 IPR019099 Uncharacterised protein family PGPGW, transmembrane CNX65_RS10090 6029be67eda9f61a6b413d0fdeefee37 139 TIGRFAM TIGR02611 TIGR02611: TIGR02611 family protein 12 122 7.5E-32 T 28-03-2018 IPR013434 Conserved hypothetical protein CHP02611 CNX65_RS13405 a768563bec47afef0bfe4add4c0041e7 441 Gene3D G3DSA:1.10.287.1060 19 104 1.8E-4 T 28-03-2018 CNX65_RS12885 680fb2a1a8e356282a697a02f9792529 270 Pfam PF08310 LGFP repeat 195 245 1.9E-4 T 28-03-2018 IPR013207 LGFP CNX65_RS32070 ba4389eb70f0565aaab39aa427a3f5a2 131 Pfam PF17252 Family of unknown function (DUF5319) 5 125 9.0E-50 T 28-03-2018 IPR035165 Protein of unknown function DUF5319 CNX65_RS32070 ba4389eb70f0565aaab39aa427a3f5a2 131 ProDom PD032647 MB3446 ML0386 RV3412/MT3521 CGL0602 8 122 7.0E-33 T 28-03-2018 IPR035165 Protein of unknown function DUF5319 CNX65_RS28650 9b312c3ceb250b1d1bcf4fb0b4c9ab85 333 Gene3D G3DSA:3.40.640.10 26 267 5.6E-22 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS28650 9b312c3ceb250b1d1bcf4fb0b4c9ab85 333 Pfam PF00266 Aminotransferase class-V 128 279 3.2E-5 T 28-03-2018 IPR000192 Aminotransferase class V domain CNX65_RS28650 9b312c3ceb250b1d1bcf4fb0b4c9ab85 333 SUPERFAMILY SSF53383 15 332 1.55E-38 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS28650 9b312c3ceb250b1d1bcf4fb0b4c9ab85 333 Gene3D G3DSA:3.90.1150.10 268 333 1.9E-6 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS31690 1f231c9e4db17a8806c695d5f9d56db3 422 Pfam PF15567 Immunity protein 35 229 314 2.2E-28 T 28-03-2018 IPR029082 Immunity protein 35 CNX65_RS31690 1f231c9e4db17a8806c695d5f9d56db3 422 Pfam PF15644 Papain fold toxin 1, glutamine deamidase 96 198 3.6E-15 T 28-03-2018 IPR028908 Tox-PL domain CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 Pfam PF02113 D-Ala-D-Ala carboxypeptidase 3 (S13) family 33 476 1.4E-127 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 TIGRFAM TIGR00666 PBP4: D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase 57 462 1.2E-102 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 Gene3D G3DSA:3.40.710.10 32 474 1.8E-35 T 28-03-2018 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 357 371 9.6E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 70 89 9.6E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 300 322 9.6E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 439 452 9.6E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 PRINTS PR00922 D-Ala-D-Ala carboxypeptidase 3 (S13) family signature 372 386 9.6E-30 T 28-03-2018 IPR000667 Peptidase S13, D-Ala-D-Ala carboxypeptidase C GO:0004185|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 CNX65_RS14125 202603c45ff1e1b64c5a1b5fe3d80936 509 SUPERFAMILY SSF56601 32 468 1.61E-94 T 28-03-2018 IPR012338 Beta-lactamase/transpeptidase-like CNX65_RS10480 b9f5c1431705e0979f1f76aaeb44f28e 258 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 245 6.2E-16 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS10480 b9f5c1431705e0979f1f76aaeb44f28e 258 SUPERFAMILY SSF161098 58 244 7.19E-31 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS10480 b9f5c1431705e0979f1f76aaeb44f28e 258 Gene3D G3DSA:1.10.3720.10 7 257 1.9E-25 T 28-03-2018 CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 Gene3D G3DSA:2.80.10.50 100 190 3.8E-12 T 28-03-2018 CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 SUPERFAMILY SSF51126 184 519 2.09E-47 T 28-03-2018 IPR011050 Pectin lyase fold/virulence factor CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 SMART SM00458 24 156 3.2E-19 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 Gene3D G3DSA:2.160.20.10 191 540 5.7E-44 T 28-03-2018 IPR012334 Pectin lyase fold CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 SUPERFAMILY SSF50370 21 157 1.06E-28 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 Pfam PF13229 Right handed beta helix region 280 469 5.2E-10 T 28-03-2018 CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 Gene3D G3DSA:2.80.10.50 72 99 8.0E-11 T 28-03-2018 CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 Gene3D G3DSA:2.80.10.50 17 71 6.8E-12 T 28-03-2018 CNX65_RS23980 1e9b6b104658e55e780234f018754df0 550 Pfam PF00652 Ricin-type beta-trefoil lectin domain 27 153 4.8E-19 T 28-03-2018 IPR000772 Ricin B, lectin domain CNX65_RS27430 c9282a8c8c2ba4b4a503bd5955b3c9be 218 Pfam PF08808 RES domain 32 195 1.2E-21 T 28-03-2018 IPR014914 RES domain CNX65_RS27430 c9282a8c8c2ba4b4a503bd5955b3c9be 218 SMART SM00953 60 190 2.1E-8 T 28-03-2018 IPR014914 RES domain CNX65_RS23600 7e24195bcdedc3938caddf7c6a048147 118 Pfam PF12769 4TM region of pyridine nucleotide transhydrogenase, mitoch 10 94 6.0E-32 T 28-03-2018 IPR024605 NAD(P) transhydrogenase, alpha subunit, C-terminal KEGG: 00760+1.6.1.2|Reactome: R-HSA-71403 CNX65_RS22270 0ef5e1657caedcb73bad48fb85f7c4b2 231 Pfam PF00881 Nitroreductase family 19 206 2.9E-27 T 28-03-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 CNX65_RS22270 0ef5e1657caedcb73bad48fb85f7c4b2 231 SUPERFAMILY SSF55469 16 81 1.57E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS22270 0ef5e1657caedcb73bad48fb85f7c4b2 231 SUPERFAMILY SSF55469 133 230 1.57E-35 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS22270 0ef5e1657caedcb73bad48fb85f7c4b2 231 Gene3D G3DSA:3.40.109.10 3 227 1.0E-47 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS21575 9417ef39ca46bb5b43bde5c047ffd0e8 1055 Pfam PF13569 Domain of unknown function (DUF4132) 789 969 2.9E-48 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS32100 50d7453dffd4bdebd66163c2c5eff9d5 98 Pfam PF02467 Transcription factor WhiB 17 85 6.3E-23 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS32100 50d7453dffd4bdebd66163c2c5eff9d5 98 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 92 18.143 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS09065 429f15da248a9d8ac863a16ba9fa2d42 95 Pfam PF02467 Transcription factor WhiB 17 87 1.4E-23 T 28-03-2018 IPR034768 WhiB-like iron-sulfur binding domain CNX65_RS09065 429f15da248a9d8ac863a16ba9fa2d42 95 Hamap MF_01479 Transcriptional regulator WhiB [whiB]. 1 93 18.553 T 28-03-2018 IPR003482 Transcription factor WhiB CNX65_RS28300 088ab4fdb0f54e0574274117e52c3ae8 354 Gene3D G3DSA:1.10.8.300 232 340 3.1E-30 T 28-03-2018 CNX65_RS28300 088ab4fdb0f54e0574274117e52c3ae8 354 Gene3D G3DSA:3.40.50.300 52 218 1.3E-25 T 28-03-2018 CNX65_RS28300 088ab4fdb0f54e0574274117e52c3ae8 354 PIRSF PIRSF002849 18 345 2.1E-130 T 28-03-2018 CNX65_RS28300 088ab4fdb0f54e0574274117e52c3ae8 354 SUPERFAMILY SSF52540 47 315 1.44E-42 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS28300 088ab4fdb0f54e0574274117e52c3ae8 354 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 71 200 1.7E-63 T 28-03-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 CNX65_RS33705 b12ab880b6aebe21a90d6d87765b98b8 266 Pfam PF14011 EspG family 10 257 2.4E-57 T 28-03-2018 IPR025734 EspG family CNX65_RS24775 770f2d08bf9f00d0605f3257d4ec5738 245 Pfam PF13490 Putative zinc-finger 11 37 6.5E-7 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS33070 dc151e48df7c3bb6e710ccfb48236b8d 495 Pfam PF13614 AAA domain 251 393 2.6E-9 T 28-03-2018 IPR025669 AAA domain CNX65_RS33070 dc151e48df7c3bb6e710ccfb48236b8d 495 Gene3D G3DSA:3.40.50.300 248 481 4.9E-25 T 28-03-2018 CNX65_RS33070 dc151e48df7c3bb6e710ccfb48236b8d 495 SUPERFAMILY SSF52540 250 465 3.23E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS23000 d183b6cc16e72488aa6dc7897e1c1629 465 Gene3D G3DSA:3.90.1150.10 340 461 6.7E-16 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS23000 d183b6cc16e72488aa6dc7897e1c1629 465 PIRSF PIRSF000521 11 458 9.4E-36 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS23000 d183b6cc16e72488aa6dc7897e1c1629 465 Gene3D G3DSA:3.90.1150.10 8 194 4.1E-27 T 28-03-2018 IPR015422 Pyridoxal phosphate-dependent transferase, subdomain 2 GO:0003824 CNX65_RS23000 d183b6cc16e72488aa6dc7897e1c1629 465 SUPERFAMILY SSF53383 162 452 1.24E-64 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS23000 d183b6cc16e72488aa6dc7897e1c1629 465 SUPERFAMILY SSF53383 20 126 1.24E-64 T 28-03-2018 IPR015424 Pyridoxal phosphate-dependent transferase CNX65_RS23000 d183b6cc16e72488aa6dc7897e1c1629 465 Gene3D G3DSA:3.40.640.10 207 339 9.1E-20 T 28-03-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major region, subdomain 1 GO:0003824 CNX65_RS23000 d183b6cc16e72488aa6dc7897e1c1629 465 Pfam PF00202 Aminotransferase class-III 20 445 6.4E-56 T 28-03-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 CNX65_RS03490 db9c72c3d85ab7aca58496d0966cb0fd 373 Pfam PF06271 RDD family 160 286 6.9E-22 T 28-03-2018 IPR010432 RDD CNX65_RS27815 191904c1e440f5ea63e88de1c59c4137 63 Pfam PF04149 Domain of unknown function (DUF397) 4 56 6.8E-17 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS27575 ad5d6dddad7df44f5d19a9b2c4a15769 320 Pfam PF02653 Branched-chain amino acid transport system / permease component 15 303 1.6E-42 T 28-03-2018 IPR001851 ABC transporter, permease GO:0005215|GO:0006810|GO:0016020 CNX65_RS27575 ad5d6dddad7df44f5d19a9b2c4a15769 320 Gene3D G3DSA:1.10.3470.10 3 306 2.2E-46 T 28-03-2018 IPR035568 ABC transporter, FecCD/TroCD-like CNX65_RS24030 cc97adbdf3e7b80a2b9b283e5adddd9d 315 Pfam PF11139 Sap, sulfolipid-1-addressing protein 91 292 1.0E-17 T 28-03-2018 IPR021315 Glycolipid exporter Gap/Sap CNX65_RS07215 eed5eb9a8337b9a9eb0dbc37c8d96075 311 Pfam PF12006 Protein of unknown function (DUF3500) 3 297 2.7E-77 T 28-03-2018 IPR021889 Protein of unknown function DUF3500 CNX65_RS22080 68124cc076939bfbc3708dc5415c7d11 320 SUPERFAMILY SSF56112 153 227 6.36E-8 T 28-03-2018 IPR011009 Protein kinase-like domain CNX65_RS22080 68124cc076939bfbc3708dc5415c7d11 320 Gene3D G3DSA:3.90.1200.10 83 305 9.1E-9 T 28-03-2018 CNX65_RS24935 eab9844bc2a9658ecd0a387cd45d4230 336 Pfam PF01497 Periplasmic binding protein 95 286 6.4E-23 T 28-03-2018 IPR002491 ABC transporter periplasmic binding domain GO:0005488 CNX65_RS24935 eab9844bc2a9658ecd0a387cd45d4230 336 SUPERFAMILY SSF53807 39 303 1.06E-45 T 28-03-2018 CNX65_RS24935 eab9844bc2a9658ecd0a387cd45d4230 336 Gene3D G3DSA:3.40.50.1980 31 168 9.4E-36 T 28-03-2018 CNX65_RS24935 eab9844bc2a9658ecd0a387cd45d4230 336 Gene3D G3DSA:3.40.50.1980 169 335 5.4E-20 T 28-03-2018 CNX65_RS24590 6c2fd31a9e3237b3e4f23127c5dc1eac 91 Pfam PF14433 SUKH-3 immunity protein 7 57 2.3E-11 T 28-03-2018 IPR025850 SUKH-3 immunity protein CNX65_RS05440 6a038d0c05572a61994d81e5edca4b85 262 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 16 204 1.7E-26 T 28-03-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal CNX65_RS05440 6a038d0c05572a61994d81e5edca4b85 262 Pfam PF02096 60Kd inner membrane protein 17 204 7.1E-25 T 28-03-2018 IPR001708 Membrane insertase OXA1/ALB3/YidC GO:0016021|GO:0051205 CNX65_RS10085 c91fd5526f8a813a7eb3e49b350d6430 271 Pfam PF10099 Anti-sigma-K factor rskA 76 265 2.6E-20 T 28-03-2018 IPR018764 Anti-sigma K factor RskA GO:0005886|GO:0016021 CNX65_RS29415 18dde9128e2eb563f57f553ed1e5fbe4 180 Pfam PF12028 Protein of unknown function (DUF3515) 19 173 3.7E-45 T 28-03-2018 IPR021903 Protein of unknown function DUF3515 CNX65_RS14175 2e7f7f06b27694ea1a57aec104d8e3d1 269 Gene3D G3DSA:3.20.20.80 95 260 1.0E-15 T 28-03-2018 CNX65_RS14175 2e7f7f06b27694ea1a57aec104d8e3d1 269 SUPERFAMILY SSF51445 98 250 1.74E-22 T 28-03-2018 IPR017853 Glycoside hydrolase superfamily CNX65_RS14175 2e7f7f06b27694ea1a57aec104d8e3d1 269 Pfam PF11790 Glycosyl hydrolase catalytic core 49 264 1.6E-50 T 28-03-2018 IPR024655 Uncharacterised protein family, glycosyl hydrolase catalytic domain CNX65_RS32025 1eccfbd0887561faa26877f732acb867 417 Pfam PF04024 PspC domain 19 70 1.0E-11 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CNX65_RS32025 1eccfbd0887561faa26877f732acb867 417 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 321 414 4.6E-7 T 28-03-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF CNX65_RS26700 26ded0226c63975b52300b474423aa46 145 Pfam PF13581 Histidine kinase-like ATPase domain 23 81 5.6E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS34650 adee88d7d68a0a56bee1b2735ceabf68 261 Gene3D G3DSA:3.40.50.1000 1 261 6.9E-38 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34650 adee88d7d68a0a56bee1b2735ceabf68 261 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 230 2.6E-21 T 28-03-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 CNX65_RS34650 adee88d7d68a0a56bee1b2735ceabf68 261 ProSitePatterns PS01229 Hypothetical cof family signature 2. 211 233 - T 28-03-2018 CNX65_RS34650 adee88d7d68a0a56bee1b2735ceabf68 261 Pfam PF08282 haloacid dehalogenase-like hydrolase 8 95 5.9E-13 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34650 adee88d7d68a0a56bee1b2735ceabf68 261 Pfam PF08282 haloacid dehalogenase-like hydrolase 179 257 7.5E-24 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS34650 adee88d7d68a0a56bee1b2735ceabf68 261 SUPERFAMILY SSF56784 4 261 2.07E-45 T 28-03-2018 IPR023214 HAD-like domain CNX65_RS32975 ede44759b7db667be16080ba8ff904e7 311 Gene3D G3DSA:1.10.620.20 1 293 3.4E-81 T 28-03-2018 CNX65_RS32975 ede44759b7db667be16080ba8ff904e7 311 TIGRFAM TIGR02156 PA_CoA_Oxy1: phenylacetate-CoA oxygenase, PaaG subunit 7 295 2.5E-150 T 28-03-2018 IPR011881 1,2-phenylacetyl-CoA epoxidase, subunit A GO:0010124|GO:0097266 KEGG: 00360+1.14.13.14+1.14.13.149|KEGG: 00940+1.14.13.14|MetaCyc: PWY-5176 CNX65_RS32975 ede44759b7db667be16080ba8ff904e7 311 SUPERFAMILY SSF47240 27 268 3.57E-79 T 28-03-2018 IPR009078 Ferritin-like superfamily CNX65_RS32975 ede44759b7db667be16080ba8ff904e7 311 Pfam PF05138 Phenylacetic acid catabolic protein 17 291 3.2E-101 T 28-03-2018 IPR007814 1,2-phenylacetyl-CoA epoxidase, subunit A/C GO:0010124 CNX65_RS00040 d065b3853defb6155dd60ab0cc94dbb1 285 Pfam PF12089 Transmembrane domain of unknown function (DUF3566) 167 283 2.0E-45 T 28-03-2018 IPR021949 Domain of unknown function DUF3566. transmembrane CNX65_RS10235 55a853009cf018f6b0313fabca175176 369 Pfam PF14072 DNA-sulfur modification-associated 8 360 2.3E-33 T 28-03-2018 IPR017642 DNA sulphur modification protein DndB CNX65_RS10235 55a853009cf018f6b0313fabca175176 369 TIGRFAM TIGR03187 DGQHR: DGQHR domain 10 298 4.5E-55 T 28-03-2018 IPR017601 DGQHR-containing domain CNX65_RS04670 e4cb1bedac08f9e1b180767db56d1e08 416 Pfam PF07730 Histidine kinase 226 292 7.1E-15 T 28-03-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 CNX65_RS04670 e4cb1bedac08f9e1b180767db56d1e08 416 Gene3D G3DSA:3.30.565.10 291 415 7.5E-14 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS04670 e4cb1bedac08f9e1b180767db56d1e08 416 Pfam PF13796 Putative sensor 15 197 9.0E-25 T 28-03-2018 IPR025828 Putative sensor domain CNX65_RS04670 e4cb1bedac08f9e1b180767db56d1e08 416 SUPERFAMILY SSF55874 301 413 5.42E-10 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS32930 24ddafb20be4e80036057c5993df6cc5 121 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 21 120 2.3E-30 T 28-03-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32930 24ddafb20be4e80036057c5993df6cc5 121 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 1 121 17.342 T 28-03-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 CNX65_RS25695 5347410b13627ff0330ee6a0cab8c63b 373 SUPERFAMILY SSF140453 104 184 1.57E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS25695 5347410b13627ff0330ee6a0cab8c63b 373 Gene3D G3DSA:1.10.287.850 95 185 8.0E-9 T 28-03-2018 CNX65_RS05015 26a958ee92b62ecdf407d7479afbc668 57 TIGRFAM TIGR01167 LPXTG_anchor: LPXTG cell wall anchor domain 19 49 1.1E-5 T 28-03-2018 CNX65_RS08510 dd438183049edf59aeab106d4c64da4f 517 Pfam PF07907 YibE/F-like protein 183 421 4.3E-71 T 28-03-2018 IPR012507 YibE/F-like CNX65_RS20225 e6b6509d37b99ca4c30a277ada968129 166 Gene3D G3DSA:1.25.40.10 1 159 2.0E-17 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20225 e6b6509d37b99ca4c30a277ada968129 166 SUPERFAMILY SSF48452 9 129 4.91E-15 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20225 e6b6509d37b99ca4c30a277ada968129 166 Pfam PF12688 Tetratrico peptide repeat 39 159 3.7E-28 T 28-03-2018 CNX65_RS07740 2eb16fee30660cda8e4201b4fc784083 279 TIGRFAM TIGR04222 near_uncomplex: TIGR04222 domain 14 199 3.3E-21 T 28-03-2018 IPR026467 Ser/Gly rich, Cys interspersed, C-terminal domain CNX65_RS26510 386cc15d8c08b29a8900aee9fc7ee371 675 Pfam PF01757 Acyltransferase family 22 336 3.3E-23 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS26510 386cc15d8c08b29a8900aee9fc7ee371 675 Gene3D G3DSA:3.40.50.1110 457 658 2.7E-5 T 28-03-2018 CNX65_RS20780 981f0634e6f7d49dce86a8abfd022135 643 Gene3D G3DSA:1.10.3680.10 471 609 1.3E-19 T 28-03-2018 IPR029024 TerB-like CNX65_RS20780 981f0634e6f7d49dce86a8abfd022135 643 Pfam PF13208 TerB N-terminal domain 73 278 1.9E-55 T 28-03-2018 IPR025266 TerB, N-terminal CNX65_RS20780 981f0634e6f7d49dce86a8abfd022135 643 SUPERFAMILY SSF158682 481 601 4.05E-23 T 28-03-2018 CNX65_RS20780 981f0634e6f7d49dce86a8abfd022135 643 Pfam PF05099 Tellurite resistance protein TerB 481 599 7.6E-16 T 28-03-2018 IPR007791 Co-chaperone DjlA, N-terminal CNX65_RS25055 1006f8d06cc69ed266f1d1b1a1acc282 491 Gene3D G3DSA:2.60.120.260 159 325 2.0E-6 T 28-03-2018 IPR008979 Galactose-binding domain-like CNX65_RS08790 2a5800e1e691c70c7b70c774e1e87e38 291 SUPERFAMILY SSF53474 77 235 2.45E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS08790 2a5800e1e691c70c7b70c774e1e87e38 291 Gene3D G3DSA:3.40.50.1820 54 286 5.6E-21 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS26350 916dfb0bc169af03c906690f7b3cd248 224 Pfam PF06197 Protein of unknown function (DUF998) 24 212 2.3E-24 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CNX65_RS22445 b60c73865c81d55f0a81fc3eb9ac76df 215 Pfam PF04892 VanZ like family 96 199 2.3E-14 T 28-03-2018 IPR006976 VanZ-like CNX65_RS00125 ca736e8647a506e957380824bb046ad4 487 Pfam PF01098 Cell cycle protein 95 459 2.4E-92 T 28-03-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 CNX65_RS19380 6d29d62343ca2016712ccfdfcfb423b4 306 Pfam PF02517 CAAX protease self-immunity 143 245 2.6E-12 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CNX65_RS08360 826b01d15d2829db630293be10865810 124 SUPERFAMILY SSF53067 14 107 4.44E-18 T 28-03-2018 CNX65_RS08360 826b01d15d2829db630293be10865810 124 Pfam PF00480 ROK family 16 100 6.4E-8 T 28-03-2018 IPR000600 ROK family Reactome: R-HSA-4085001 CNX65_RS08360 826b01d15d2829db630293be10865810 124 Gene3D G3DSA:3.30.420.40 2 116 3.3E-19 T 28-03-2018 CNX65_RS23655 565f5be59cb642d2466260c56d1d16d4 149 Pfam PF07681 DoxX 23 98 2.7E-8 T 28-03-2018 IPR032808 DoxX family CNX65_RS12550 5b4a2490ca4335e5272066806a45511b 334 TIGRFAM TIGR03718 R_switched_Alx: integral membrane protein, TerC family 6 311 2.0E-113 T 28-03-2018 IPR022369 Integral membrane protein TerC, riboswitch-linked GO:0016021 CNX65_RS12550 5b4a2490ca4335e5272066806a45511b 334 Pfam PF03741 Integral membrane protein TerC family 70 273 1.5E-51 T 28-03-2018 IPR005496 Integral membrane protein TerC GO:0016021 CNX65_RS19785 3375acbc7a07dc60c31403771da28cf3 133 Gene3D G3DSA:3.30.565.10 7 133 4.1E-12 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19785 3375acbc7a07dc60c31403771da28cf3 133 Pfam PF13581 Histidine kinase-like ATPase domain 23 126 9.0E-7 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS19785 3375acbc7a07dc60c31403771da28cf3 133 SUPERFAMILY SSF55874 45 129 6.02E-8 T 28-03-2018 IPR003594 Histidine kinase-like ATPase, C-terminal domain CNX65_RS18835 8818131919dad478628170a4c67f1816 376 Pfam PF07070 SpoOM protein 2 217 8.2E-79 T 28-03-2018 IPR009776 Sporulation stage 0, protein M CNX65_RS24240 9c4d26b04e7073056ab63cd6d34bf616 124 Pfam PF13340 Putative transposase of IS4/5 family (DUF4096) 7 61 1.3E-12 T 28-03-2018 IPR025161 Putative transposase IS4/IS5 family CNX65_RS13100 c9abf834b45e4ebd8982c588d8a35978 149 SUPERFAMILY SSF160424 7 141 2.09E-25 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS14840 022298a8f6f746d0900857894585a284 135 Gene3D G3DSA:3.10.450.40 1 130 1.0E-41 T 28-03-2018 CNX65_RS14840 022298a8f6f746d0900857894585a284 135 SUPERFAMILY SSF160719 21 128 2.35E-34 T 28-03-2018 CNX65_RS14840 022298a8f6f746d0900857894585a284 135 Pfam PF04965 Gene 25-like lysozyme 26 115 7.9E-26 T 28-03-2018 IPR007048 GpW/Gp25/anti-adapter protein IraD CNX65_RS01085 0af8e7c69c613167f07820f1c9dece8b 79 Gene3D G3DSA:1.10.287.1060 1 77 5.3E-4 T 28-03-2018 CNX65_RS06130 e92e11108e9d40e4f5564d51b1fe4b4b 67 SUPERFAMILY SSF143100 6 56 2.09E-9 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CNX65_RS06130 e92e11108e9d40e4f5564d51b1fe4b4b 67 Gene3D G3DSA:3.30.2390.10 6 61 3.9E-11 T 28-03-2018 IPR035069 TTHA1013/TTHA0281-like CNX65_RS34140 c98111121b2be2656e191eb93ebf003a 223 Gene3D G3DSA:3.40.50.10330 21 116 2.7E-5 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CNX65_RS15725 fe8666d228876dd3035536914fae3c57 379 Gene3D G3DSA:3.40.630.30 128 272 5.7E-7 T 28-03-2018 CNX65_RS15725 fe8666d228876dd3035536914fae3c57 379 Pfam PF13527 Acetyltransferase (GNAT) domain 3 124 1.2E-16 T 28-03-2018 CNX65_RS15725 fe8666d228876dd3035536914fae3c57 379 SUPERFAMILY SSF55729 1 224 1.78E-26 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS15725 fe8666d228876dd3035536914fae3c57 379 Gene3D G3DSA:3.40.630.30 1 127 3.7E-14 T 28-03-2018 CNX65_RS34805 48f0bd927911838721dccd7ade24a469 297 Pfam PF13556 PucR C-terminal helix-turn-helix domain 235 293 1.7E-10 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 303 321 5.8E-42 T 28-03-2018 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 270 285 5.8E-42 T 28-03-2018 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 4 26 5.8E-42 T 28-03-2018 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 142 157 5.8E-42 T 28-03-2018 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 321 337 5.8E-42 T 28-03-2018 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 285 301 5.8E-42 T 28-03-2018 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 SUPERFAMILY SSF51905 2 163 4.52E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 SUPERFAMILY SSF51905 257 361 4.52E-56 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 Pfam PF01494 FAD binding domain 2 335 1.4E-76 T 28-03-2018 IPR002938 FAD-binding domain GO:0071949 CNX65_RS15765 00d95eaa8af71a0cfce6383396d3070f 483 Gene3D G3DSA:3.50.50.60 1 384 9.0E-53 T 28-03-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 CNX65_RS00220 6a689c1b75d902a86f547c247b29ce8a 339 Pfam PF05425 Copper resistance protein D 230 333 9.0E-18 T 28-03-2018 IPR008457 Copper resistance protein D GO:0016021 CNX65_RS10850 d97b0a7a751330f358cc66b149e92dd1 64 Pfam PF04149 Domain of unknown function (DUF397) 7 58 5.7E-11 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS11300 bbc544e7181fadccecd835dc9e27f839 312 Pfam PF03547 Membrane transport protein 152 307 2.8E-17 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CNX65_RS11300 bbc544e7181fadccecd835dc9e27f839 312 Pfam PF03547 Membrane transport protein 8 131 4.6E-12 T 28-03-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 CNX65_RS00990 6036f9468708a310b8b5f2a9657a25e6 191 Pfam PF09335 SNARE associated Golgi protein 17 141 8.2E-11 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS12120 6de5592aac1d324cf42e387227549dfd 108 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 8 103 3.4E-14 T 28-03-2018 IPR008407 Branched-chain amino acid transport, AzlD CNX65_RS15025 8611c8023e89911660c3c51d0226f641 305 SUPERFAMILY SSF161098 59 293 1.7E-56 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS15025 8611c8023e89911660c3c51d0226f641 305 Gene3D G3DSA:1.10.3720.10 18 303 1.2E-51 T 28-03-2018 CNX65_RS15025 8611c8023e89911660c3c51d0226f641 305 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 93 300 4.1E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS18790 1a0a6c51c55011a7c6f64f230fb23f8c 139 Gene3D G3DSA:1.10.1740.10 2 51 1.7E-4 T 28-03-2018 CNX65_RS31415 6e1a7f75bc1b3b3a928d32037d4cdc83 128 Pfam PF08044 Domain of unknown function (DUF1707) 6 58 2.3E-20 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CNX65_RS34095 d25c8cd1ddc63eec32cbebca66340484 258 Pfam PF14011 EspG family 11 252 6.1E-67 T 28-03-2018 IPR025734 EspG family CNX65_RS01695 8b4266cf450b0e2933787b3010cccf4d 116 Pfam PF11774 Lsr2 1 114 2.1E-41 T 28-03-2018 IPR024412 Lsr2 CNX65_RS01695 8b4266cf450b0e2933787b3010cccf4d 116 ProDom PD026347 LSR2-LIKE LSR2 ANTIGEN IMMUNE PRECURSOR RESPONSE SIGNAL PLASMID LYSYL GP61 1 112 6.0E-23 T 28-03-2018 IPR024412 Lsr2 CNX65_RS24835 c9c0cfea04ddb2ff60ae16bda69cbed5 71 Pfam PF04149 Domain of unknown function (DUF397) 6 70 4.8E-20 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS18210 24bc8b66eb05ae680ca643434b8e8333 250 Pfam PF08327 Activator of Hsp90 ATPase homolog 1-like protein 15 128 1.3E-5 T 28-03-2018 IPR013538 Activator of Hsp90 ATPase homologue 1-like GO:0006950 CNX65_RS18210 24bc8b66eb05ae680ca643434b8e8333 250 SUPERFAMILY SSF55961 6 129 4.87E-18 T 28-03-2018 CNX65_RS18210 24bc8b66eb05ae680ca643434b8e8333 250 Gene3D G3DSA:3.30.530.20 2 157 9.5E-19 T 28-03-2018 IPR023393 START-like domain CNX65_RS02285 04ca903ca7fefde983fce577bf81313f 84 Pfam PF04024 PspC domain 25 83 1.2E-17 T 28-03-2018 IPR007168 Phage shock protein, PspC, N-terminal CNX65_RS03195 b14dc5e471d5cb2ea972b0be8e2c8aa0 227 SUPERFAMILY SSF161098 13 206 4.97E-40 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS03195 b14dc5e471d5cb2ea972b0be8e2c8aa0 227 Gene3D G3DSA:1.10.3720.10 7 222 2.0E-33 T 28-03-2018 CNX65_RS03195 b14dc5e471d5cb2ea972b0be8e2c8aa0 227 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 36 223 1.4E-20 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS29905 5aed890ac2ccde695454d89b9f91e27b 461 SUPERFAMILY SSF55486 113 251 3.99E-7 T 28-03-2018 CNX65_RS29905 5aed890ac2ccde695454d89b9f91e27b 461 Pfam PF04228 Putative neutral zinc metallopeptidase 53 252 5.7E-12 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CNX65_RS14665 2a85711bbbe5489e46438b77efde8e5d 1126 Pfam PF13569 Domain of unknown function (DUF4132) 853 1034 8.0E-50 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS14665 2a85711bbbe5489e46438b77efde8e5d 1126 Gene3D G3DSA:1.25.60.10 56 308 0.017 T 28-03-2018 CNX65_RS24570 3db13a8f3e3d73bf635e415091fee45d 873 TIGRFAM TIGR03696 Rhs_assc_core: RHS repeat-associated core domain 687 775 1.8E-13 T 28-03-2018 IPR022385 Rhs repeat-associated core GO:0097264 CNX65_RS24570 3db13a8f3e3d73bf635e415091fee45d 873 Pfam PF13385 Concanavalin A-like lectin/glucanases superfamily 2 79 1.8E-16 T 28-03-2018 CNX65_RS24570 3db13a8f3e3d73bf635e415091fee45d 873 SUPERFAMILY SSF49899 5 84 2.6E-15 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS24570 3db13a8f3e3d73bf635e415091fee45d 873 Gene3D G3DSA:2.60.120.200 1 85 2.2E-16 T 28-03-2018 CNX65_RS01560 600d555179bee9e9a247c7e4159127f2 227 SUPERFAMILY SSF50199 74 178 1.02E-11 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CNX65_RS01560 600d555179bee9e9a247c7e4159127f2 227 Gene3D G3DSA:2.40.50.90 74 185 2.8E-9 T 28-03-2018 IPR035437 Staphylococcal nuclease (SNase-like), OB-fold/extended TUDOR domain CNX65_RS01560 600d555179bee9e9a247c7e4159127f2 227 SMART SM00318 74 178 0.0057 T 28-03-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold CNX65_RS01450 2c7e0e4105276d3d7cf9991aae99e151 109 TIGRFAM TIGR03816 tadE_like_DECH: helicase/secretion neighborhood TadE-like protein 5 109 1.8E-25 T 28-03-2018 IPR021202 Apoptosis inhibitor Rv3654c-like CNX65_RS01450 2c7e0e4105276d3d7cf9991aae99e151 109 Pfam PF13400 Putative Flp pilus-assembly TadE/G-like 7 53 5.0E-8 T 28-03-2018 IPR028087 Putative Flp pilus-assembly TadG-like, N-terminal CNX65_RS06375 7cc17880d6fe15880e7c543ede61991a 286 SUPERFAMILY SSF56349 4 265 2.06E-44 T 28-03-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 CNX65_RS06375 7cc17880d6fe15880e7c543ede61991a 286 Gene3D G3DSA:1.10.150.130 1 79 5.9E-12 T 28-03-2018 IPR023109 Integrase/recombinase, N-terminal CNX65_RS06375 7cc17880d6fe15880e7c543ede61991a 286 Gene3D G3DSA:1.10.443.10 80 281 7.1E-30 T 28-03-2018 IPR013762 Integrase-like, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS06375 7cc17880d6fe15880e7c543ede61991a 286 Pfam PF00589 Phage integrase family 78 265 1.1E-13 T 28-03-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 CNX65_RS15305 dc8a039eea38c57f5331d00cea654115 275 SUPERFAMILY SSF53474 16 273 1.84E-5 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS31640 10ef6ab0e7a73bc73a9c4ef014bd5fbf 147 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 29 119 9.8E-10 T 28-03-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain CNX65_RS31640 10ef6ab0e7a73bc73a9c4ef014bd5fbf 147 Gene3D G3DSA:3.40.140.10 13 147 2.1E-37 T 28-03-2018 CNX65_RS31640 10ef6ab0e7a73bc73a9c4ef014bd5fbf 147 SUPERFAMILY SSF53927 23 146 1.81E-36 T 28-03-2018 IPR016193 Cytidine deaminase-like GO:0003824 CNX65_RS29315 50ca66f1dece80d74015aaf90f896b11 360 SUPERFAMILY SSF56281 200 347 1.7E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS29315 50ca66f1dece80d74015aaf90f896b11 360 SUPERFAMILY SSF56281 95 172 1.7E-38 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS29315 50ca66f1dece80d74015aaf90f896b11 360 Pfam PF12706 Beta-lactamase superfamily domain 113 308 1.4E-52 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS29315 50ca66f1dece80d74015aaf90f896b11 360 Gene3D G3DSA:3.60.15.10 64 352 1.1E-56 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS30055 602a5c3b41f7f944833578c58d0d75e7 97 Gene3D G3DSA:2.10.110.10 40 88 0.0014 T 28-03-2018 CNX65_RS04565 dc5b22b91b633c81003a98db62749e4b 297 SUPERFAMILY SSF53335 23 224 4.69E-26 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS04565 dc5b22b91b633c81003a98db62749e4b 297 Gene3D G3DSA:3.40.50.150 3 261 1.4E-24 T 28-03-2018 CNX65_RS04565 dc5b22b91b633c81003a98db62749e4b 297 Pfam PF08241 Methyltransferase domain 47 158 7.7E-10 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS22320 8f75109f5158be5af52e53348da2577b 140 Gene3D G3DSA:3.10.450.50 2 139 8.4E-23 T 28-03-2018 CNX65_RS22320 8f75109f5158be5af52e53348da2577b 140 SUPERFAMILY SSF54427 4 137 1.44E-20 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS22320 8f75109f5158be5af52e53348da2577b 140 Pfam PF12680 SnoaL-like domain 10 120 1.1E-12 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS17295 2d925cd42adfa17084be8e90c53857c1 258 Gene3D G3DSA:3.20.20.190 1 258 1.1E-61 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS17295 2d925cd42adfa17084be8e90c53857c1 258 SUPERFAMILY SSF51695 11 249 2.33E-59 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS17295 2d925cd42adfa17084be8e90c53857c1 258 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 13 243 1.2E-33 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CNX65_RS21375 38b7a22c07466f6f4e2230405568ecac 972 Pfam PF13569 Domain of unknown function (DUF4132) 742 889 2.2E-40 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS19965 2084355e3da03def03856082a74c1eff 251 SUPERFAMILY SSF49899 31 249 2.71E-70 T 28-03-2018 IPR013320 Concanavalin A-like lectin/glucanase domain CNX65_RS19965 2084355e3da03def03856082a74c1eff 251 Pfam PF01670 Glycosyl hydrolase family 12 44 248 1.3E-66 T 28-03-2018 IPR002594 Glycoside hydrolase family 12 GO:0000272|GO:0008810 CNX65_RS19965 2084355e3da03def03856082a74c1eff 251 Gene3D G3DSA:2.60.120.180 29 251 6.3E-75 T 28-03-2018 IPR013319 Glycoside hydrolase family 11/12 GO:0004553 MetaCyc: PWY-6784 CNX65_RS34975 b4493c9caa8ecc848203159669b3f040 764 Gene3D G3DSA:2.60.40.10 620 715 0.0014 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS34975 b4493c9caa8ecc848203159669b3f040 764 Gene3D G3DSA:2.60.40.10 43 242 1.1E-6 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS17170 96e8c04f6d1e7a18c7290cb49b15841b 193 SUPERFAMILY SSF52218 2 189 2.35E-44 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS17170 96e8c04f6d1e7a18c7290cb49b15841b 193 Gene3D G3DSA:3.40.50.360 2 192 1.6E-37 T 28-03-2018 IPR029039 Flavoprotein-like domain CNX65_RS17170 96e8c04f6d1e7a18c7290cb49b15841b 193 Pfam PF02525 Flavodoxin-like fold 2 184 1.4E-45 T 28-03-2018 IPR003680 Flavodoxin-like fold CNX65_RS13410 b7b0228d45706fa853e9adfb63bdf1bd 177 Gene3D G3DSA:1.10.287.1060 2 94 1.8E-6 T 28-03-2018 CNX65_RS19775 9a4efb6aef834ba6a4c5d713b773b784 104 SUPERFAMILY SSF52091 10 81 5.3E-10 T 28-03-2018 IPR002645 STAS domain CNX65_RS19775 9a4efb6aef834ba6a4c5d713b773b784 104 Gene3D G3DSA:3.30.750.24 3 98 1.7E-9 T 28-03-2018 IPR002645 STAS domain CNX65_RS19775 9a4efb6aef834ba6a4c5d713b773b784 104 Pfam PF13466 STAS domain 19 76 3.5E-10 T 28-03-2018 IPR002645 STAS domain CNX65_RS03630 c0041c5ee0e6ea191975265b6249a5fe 314 Pfam PF02401 LytB protein 5 282 4.1E-90 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CNX65_RS03630 c0041c5ee0e6ea191975265b6249a5fe 314 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 5 284 1.2E-98 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CNX65_RS03630 c0041c5ee0e6ea191975265b6249a5fe 314 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 3 286 37.271 T 28-03-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 CNX65_RS06965 e5e942f7a54e8c32fd953a89a1230620 167 Pfam PF04073 Aminoacyl-tRNA editing domain 35 156 3.2E-26 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS06965 e5e942f7a54e8c32fd953a89a1230620 167 Gene3D G3DSA:3.90.960.10 2 167 2.7E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS06965 e5e942f7a54e8c32fd953a89a1230620 167 SUPERFAMILY SSF55826 13 165 1.7E-31 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS24975 5c1a33b03b9e14be86044977386bb33b 71 Pfam PF04149 Domain of unknown function (DUF397) 9 65 7.6E-19 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS05680 452c5c9a6c97c9100c0e0ba0096cc650 160 Pfam PF17174 Domain of unknown function (DUF5130) 18 151 3.1E-36 T 28-03-2018 IPR033437 Protein of unknown function DUF5130 CNX65_RS04835 8f697fccdec19ef73286bcc8fa3059c0 1003 SUPERFAMILY SSF52540 265 374 2.31E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04835 8f697fccdec19ef73286bcc8fa3059c0 1003 SUPERFAMILY SSF52540 59 125 2.31E-5 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS04835 8f697fccdec19ef73286bcc8fa3059c0 1003 Gene3D G3DSA:3.40.50.300 54 369 2.9E-6 T 28-03-2018 CNX65_RS33970 5ee7bb1d864af72f6246c4c127a48708 327 Gene3D G3DSA:2.160.20.80 162 294 8.8E-10 T 28-03-2018 CNX65_RS33970 5ee7bb1d864af72f6246c4c127a48708 327 Pfam PF13576 Pentapeptide repeats (9 copies) 208 253 7.8E-8 T 28-03-2018 IPR001646 Pentapeptide repeat CNX65_RS33970 5ee7bb1d864af72f6246c4c127a48708 327 Gene3D G3DSA:1.25.10.20 28 161 1.4E-4 T 28-03-2018 CNX65_RS21175 0725b91f5aef80c094fc909e013c4418 342 SUPERFAMILY SSF52540 69 284 1.56E-25 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS21175 0725b91f5aef80c094fc909e013c4418 342 Gene3D G3DSA:3.40.50.300 67 297 5.4E-25 T 28-03-2018 CNX65_RS21175 0725b91f5aef80c094fc909e013c4418 342 SMART SM00382 78 264 1.2E-10 T 28-03-2018 IPR003593 AAA+ ATPase domain CNX65_RS21175 0725b91f5aef80c094fc909e013c4418 342 Pfam PF07728 AAA domain (dynein-related subfamily) 82 209 6.9E-6 T 28-03-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 CNX65_RS02520 547a9bd8d670fc0671ac327f25fe15e1 497 PIRSF PIRSF012666 1 497 1.4E-209 T 28-03-2018 IPR016602 Uncharacterised conserved protein UCP012666 CNX65_RS02520 547a9bd8d670fc0671ac327f25fe15e1 497 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 195 254 8.2E-6 T 28-03-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 CNX65_RS02520 547a9bd8d670fc0671ac327f25fe15e1 497 SUPERFAMILY SSF55931 36 154 5.4E-53 T 28-03-2018 CNX65_RS02520 547a9bd8d670fc0671ac327f25fe15e1 497 SUPERFAMILY SSF55931 184 466 5.4E-53 T 28-03-2018 CNX65_RS29090 e536c70edeef6bb02ecddd20cdc21065 238 Pfam PF02517 CAAX protease self-immunity 136 223 5.5E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CNX65_RS27425 217766e37631547237f745169a00b2e8 194 Gene3D G3DSA:1.10.10.10 65 106 0.31 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS18545 585e2d8b7cd808948b02fe3cf14ef223 506 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 20 437 5.1E-146 T 28-03-2018 IPR002823 Protein of unknown function DUF112, transmembrane CNX65_RS09475 2520d204bd0fa02e8e47c1505aae227e 242 Pfam PF14428 SCP1.201-like deaminase 101 236 2.2E-34 T 28-03-2018 IPR032724 Deaminase, SCP1.201-like CNX65_RS23875 deea9a85fe9fc1b17990c6dae6b362e2 159 Gene3D G3DSA:3.40.50.150 74 159 8.7E-4 T 28-03-2018 CNX65_RS23820 7ae0bdf7b4e85ba012810152f1d709a7 279 SUPERFAMILY SSF51556 2 276 1.11E-36 T 28-03-2018 IPR032466 Metal-dependent hydrolase CNX65_RS23820 7ae0bdf7b4e85ba012810152f1d709a7 279 Pfam PF04909 Amidohydrolase 5 274 1.4E-27 T 28-03-2018 IPR006680 Amidohydrolase-related GO:0016787 CNX65_RS23820 7ae0bdf7b4e85ba012810152f1d709a7 279 Gene3D G3DSA:3.20.20.140 2 278 2.5E-39 T 28-03-2018 CNX65_RS34455 2d00d55f6ab99ec0805f9fab56638ed4 412 SUPERFAMILY SSF103088 290 405 1.31E-16 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS34455 2d00d55f6ab99ec0805f9fab56638ed4 412 Pfam PF00691 OmpA family 299 386 4.6E-11 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS34455 2d00d55f6ab99ec0805f9fab56638ed4 412 Gene3D G3DSA:3.30.1330.60 47 410 1.3E-20 T 28-03-2018 IPR006665 OmpA-like domain CNX65_RS30060 e07f225e6bc769a5fec07fb0cffd4794 69 TIGRFAM TIGR02605 CxxC_CxxC_SSSS: putative regulatory protein, FmdB family 2 46 7.1E-15 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CNX65_RS30060 e07f225e6bc769a5fec07fb0cffd4794 69 Pfam PF09723 Zinc ribbon domain 2 40 2.6E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CNX65_RS30060 e07f225e6bc769a5fec07fb0cffd4794 69 SMART SM00834 2 42 4.6E-12 T 28-03-2018 IPR013429 Putative regulatory protein, FmdB, Zinc ribbon domain CNX65_RS13360 ded0e531eebb17538d07fb458f5c7f21 73 Gene3D G3DSA:1.10.150.20 21 73 6.2E-4 T 28-03-2018 CNX65_RS18480 68985d33dd8718b0d398769a3aed1bc5 633 Pfam PF01435 Peptidase family M48 117 289 2.7E-6 T 28-03-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 CNX65_RS08380 2ad6868d5e6d77d68c0748f9f7593a61 326 Gene3D G3DSA:1.10.3720.10 2 312 6.0E-32 T 28-03-2018 CNX65_RS08380 2ad6868d5e6d77d68c0748f9f7593a61 326 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 118 324 2.0E-38 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS08380 2ad6868d5e6d77d68c0748f9f7593a61 326 SUPERFAMILY SSF161098 95 323 1.16E-15 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS19205 7590834036a5478d981b89027133c6a8 218 Gene3D G3DSA:2.30.30.410 36 148 2.3E-5 T 28-03-2018 CNX65_RS26725 07d861acc9f69905f1bc2d2e45d4dd5d 247 Pfam PF14325 Domain of unknown function (DUF4383) 23 146 5.4E-25 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CNX65_RS29575 8389bd8837f33c7e705df5a1d191c99f 217 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 143 160 1.6E-9 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS29575 8389bd8837f33c7e705df5a1d191c99f 217 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 122 142 1.6E-9 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS29575 8389bd8837f33c7e705df5a1d191c99f 217 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 186 200 1.6E-9 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS29575 8389bd8837f33c7e705df5a1d191c99f 217 PRINTS PR00861 Alpha-lytic endopeptidase serine protease (S2A) signature 162 185 1.6E-9 T 28-03-2018 IPR001316 Peptidase S1A, streptogrisin GO:0004252|GO:0006508 CNX65_RS15000 aaa0d74f8447dfedf69a57565baadd0a 260 Pfam PF07920 Protein of unknown function (DUF1684) 118 255 1.7E-44 T 28-03-2018 IPR012467 Protein of unknown function DUF1684 CNX65_RS03705 dc885d0ae32f609e35ec1c812df216ad 926 Gene3D G3DSA:3.30.1120.50 30 64 4.1E-5 T 28-03-2018 CNX65_RS30040 62c74730be470893b816958665d1eb83 435 Gene3D G3DSA:1.20.120.330 24 152 5.2E-5 T 28-03-2018 CNX65_RS30040 62c74730be470893b816958665d1eb83 435 Gene3D G3DSA:1.20.5.1230 197 380 0.15 T 28-03-2018 CNX65_RS12775 a1f3f72cc17f10376f0e406613d026dd 151 SUPERFAMILY SSF55298 3 148 2.83E-48 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS12775 a1f3f72cc17f10376f0e406613d026dd 151 Pfam PF14588 YjgF/chorismate_mutase-like, putative endoribonuclease 5 146 1.1E-25 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS12775 a1f3f72cc17f10376f0e406613d026dd 151 Gene3D G3DSA:3.30.1330.40 3 151 1.7E-27 T 28-03-2018 IPR013813 Endoribonuclease L-PSP/chorismate mutase-like CNX65_RS02700 dab7c9d40170c8d2daffb01dbae95916 413 Pfam PF12698 ABC-2 family transporter protein 33 378 8.8E-38 T 28-03-2018 CNX65_RS11160 deda02edbc88ba1bb0a0adb775bab37e 255 Pfam PF12079 Protein of unknown function (DUF3558) 68 252 4.4E-24 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS30570 4b48e506783fd3b26c0b610b98446773 466 Pfam PF13777 Domain of unknown function (DUF4173) 236 425 3.3E-62 T 28-03-2018 IPR025231 Domain of unknown function DUF4173 CNX65_RS00395 5d34a20046d4e4f16805bed2868aa0ac 232 Gene3D G3DSA:3.20.20.190 1 230 1.7E-53 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS00395 5d34a20046d4e4f16805bed2868aa0ac 232 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 8 160 1.7E-27 T 28-03-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 CNX65_RS00395 5d34a20046d4e4f16805bed2868aa0ac 232 SUPERFAMILY SSF51695 3 226 1.36E-57 T 28-03-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain GO:0006629|GO:0008081 CNX65_RS11915 bcf9c71fecf50d74df9c58997b98b789 139 Pfam PF03963 Flagellar hook capping protein - N-terminal region 10 74 1.1E-16 T 28-03-2018 IPR005648 Flagellar hook capping protein CNX65_RS05450 7a8f81b5771e76be76e18718a963ea22 206 Gene3D G3DSA:3.40.50.300 41 191 2.5E-4 T 28-03-2018 CNX65_RS33360 0c3b1e10a45e7c180dc476ecbdbd1b09 184 Gene3D G3DSA:3.90.960.10 24 179 1.4E-25 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS33360 0c3b1e10a45e7c180dc476ecbdbd1b09 184 SUPERFAMILY SSF55826 43 178 2.09E-23 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS33360 0c3b1e10a45e7c180dc476ecbdbd1b09 184 Pfam PF04073 Aminoacyl-tRNA editing domain 48 170 2.3E-17 T 28-03-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 CNX65_RS32880 f3a35aa8a7634d1a33b1927308bdfae2 99 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 6 93 3.6E-24 T 28-03-2018 CNX65_RS32880 f3a35aa8a7634d1a33b1927308bdfae2 99 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 1 99 20.191 T 28-03-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 CNX65_RS15480 b3400cb59d1a35ee606103b25f9a3402 119 SUPERFAMILY SSF54427 10 114 8.36E-20 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS15480 b3400cb59d1a35ee606103b25f9a3402 119 Gene3D G3DSA:3.10.450.50 3 113 9.2E-16 T 28-03-2018 CNX65_RS15480 b3400cb59d1a35ee606103b25f9a3402 119 Pfam PF12680 SnoaL-like domain 17 85 3.3E-8 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS26890 b20b16246cb3245e5af412e80f0cd0da 308 Gene3D G3DSA:3.30.1330.30 219 307 1.7E-6 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS26890 b20b16246cb3245e5af412e80f0cd0da 308 SUPERFAMILY SSF55315 224 297 1.02E-5 T 28-03-2018 IPR029064 50S ribosomal protein L30e-like CNX65_RS26890 b20b16246cb3245e5af412e80f0cd0da 308 Gene3D G3DSA:3.30.420.60 155 206 2.2E-5 T 28-03-2018 CNX65_RS24280 4c2fd8e0b13101472a2cddf74173ccbd 397 Pfam PF13556 PucR C-terminal helix-turn-helix domain 330 387 1.0E-17 T 28-03-2018 IPR025736 PucR C-terminal helix-turn-helix domain CNX65_RS24280 4c2fd8e0b13101472a2cddf74173ccbd 397 Gene3D G3DSA:1.10.10.60 325 367 8.0E-4 T 28-03-2018 CNX65_RS10230 23c938bd3876ef93d20de9d6055b2365 513 Pfam PF13148 Protein of unknown function (DUF3987) 61 423 2.9E-96 T 28-03-2018 IPR025048 Protein of unknown function DUF3987) CNX65_RS07800 74779b7768a64d202ac2c73df572703a 334 TIGRFAM TIGR02778 ligD_pol: DNA ligase D, polymerase domain 14 258 7.9E-68 T 28-03-2018 IPR014145 DNA ligase D, polymerase domain CNX65_RS26465 f872887d47ae82c5ec901e0ca2e87ac8 215 Pfam PF03473 MOSC domain 54 165 5.8E-21 T 28-03-2018 IPR005302 Molybdenum cofactor sulfurase, C-terminal GO:0003824|GO:0030151|GO:0030170 CNX65_RS26465 f872887d47ae82c5ec901e0ca2e87ac8 215 SUPERFAMILY SSF50800 1 213 2.72E-58 T 28-03-2018 IPR011037 Pyruvate kinase-like, insert domain CNX65_RS26465 f872887d47ae82c5ec901e0ca2e87ac8 215 Gene3D G3DSA:2.40.33.20 1 215 9.7E-48 T 28-03-2018 CNX65_RS00465 d8732dc7497a39290a73e36076346828 503 PIRSF PIRSF006446 1 491 3.7E-135 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CNX65_RS00465 d8732dc7497a39290a73e36076346828 503 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 6 468 4.1E-165 T 28-03-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 CNX65_RS22805 76f7ee7e3af37e6f64f2af5cefdbe258 246 Pfam PF08889 WbqC-like protein family 8 215 2.9E-47 T 28-03-2018 IPR014985 WbqC-like protein family CNX65_RS06825 07c4e7785cb52a02a6a34f2d4232ad7d 507 Pfam PF05991 YacP-like NYN domain 387 504 7.1E-20 T 28-03-2018 IPR010298 Protein of unknown function DUF901 CNX65_RS26595 8c9b2950266b8d88761a9ec8f9180754 473 Pfam PF04261 Dyp-type peroxidase family 262 404 5.2E-8 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CNX65_RS26595 8c9b2950266b8d88761a9ec8f9180754 473 SUPERFAMILY SSF54909 23 466 1.1E-86 T 28-03-2018 IPR011008 Dimeric alpha-beta barrel CNX65_RS26595 8c9b2950266b8d88761a9ec8f9180754 473 TIGRFAM TIGR01413 Dyp_perox_fam: Dyp-type peroxidase family 153 461 1.6E-31 T 28-03-2018 IPR006314 Dyp-type peroxidase GO:0004601|GO:0020037|GO:0055114 CNX65_RS00715 119d704ffe83d50f00d8964174e9512c 301 SUPERFAMILY SSF55486 90 137 1.83E-5 T 28-03-2018 CNX65_RS00715 119d704ffe83d50f00d8964174e9512c 301 SUPERFAMILY SSF55486 171 262 1.83E-5 T 28-03-2018 CNX65_RS00715 119d704ffe83d50f00d8964174e9512c 301 Pfam PF04228 Putative neutral zinc metallopeptidase 11 295 1.2E-70 T 28-03-2018 IPR007343 Uncharacterised protein family, zinc metallopeptidase putative CNX65_RS13000 86699e639352c6f700057bb176a44347 406 Pfam PF10923 P-loop Domain of unknown function (DUF2791) 5 383 1.1E-92 T 28-03-2018 IPR021228 Protein of unknown function DUF2791 CNX65_RS13000 86699e639352c6f700057bb176a44347 406 Gene3D G3DSA:3.40.50.300 28 382 7.2E-6 T 28-03-2018 CNX65_RS34880 81bfb94953a5bd951070a371e9a28e4d 171 Pfam PF14428 SCP1.201-like deaminase 88 149 2.6E-8 T 28-03-2018 IPR032724 Deaminase, SCP1.201-like CNX65_RS26790 018f02584e5c4941736bd851ac673708 179 Pfam PF09684 Phage tail protein (Tail_P2_I) 33 160 1.4E-13 T 28-03-2018 IPR006521 Tail protein I CNX65_RS26790 018f02584e5c4941736bd851ac673708 179 TIGRFAM TIGR02242 tail_TIGR02242: phage tail protein domain 17 120 3.7E-31 T 28-03-2018 IPR011748 Uncharacterised protein family, phage tail-like CNX65_RS31090 6ca0b398480f33e92792367508f86987 215 SUPERFAMILY SSF52540 2 200 1.11E-26 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS31090 6ca0b398480f33e92792367508f86987 215 Gene3D G3DSA:3.40.50.300 1 210 5.0E-28 T 28-03-2018 CNX65_RS31090 6ca0b398480f33e92792367508f86987 215 Pfam PF02223 Thymidylate kinase 7 157 4.2E-17 T 28-03-2018 CNX65_RS31090 6ca0b398480f33e92792367508f86987 215 Hamap MF_00165 Thymidylate kinase [tmk]. 3 215 12.669 T 28-03-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 CNX65_RS08505 cbc0ec84d24365ab2a072c04f8ee8b86 120 Pfam PF06993 Protein of unknown function (DUF1304) 10 117 4.2E-38 T 28-03-2018 IPR009732 Protein of unknown function DUF1304 CNX65_RS07860 96d526632f2b8528b19ec80aebb72b0a 345 Gene3D G3DSA:2.130.10.10 8 285 3.3E-34 T 28-03-2018 IPR015943 WD40/YVTN repeat-like-containing domain GO:0005515 CNX65_RS07860 96d526632f2b8528b19ec80aebb72b0a 345 Gene3D G3DSA:2.120.10.30 286 345 1.1E-4 T 28-03-2018 IPR011042 Six-bladed beta-propeller, TolB-like CNX65_RS07860 96d526632f2b8528b19ec80aebb72b0a 345 Pfam PF10282 Lactonase, 7-bladed beta-propeller 11 345 3.3E-101 T 28-03-2018 IPR019405 Lactonase, 7-bladed beta propeller CNX65_RS07860 96d526632f2b8528b19ec80aebb72b0a 345 SUPERFAMILY SSF51004 49 338 7.98E-38 T 28-03-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain CNX65_RS03320 034950078bb7731eaf4af8a5743e37c1 311 SUPERFAMILY SSF53955 129 296 6.66E-34 T 28-03-2018 IPR023346 Lysozyme-like domain CNX65_RS03320 034950078bb7731eaf4af8a5743e37c1 311 Gene3D G3DSA:1.10.530.10 105 308 2.9E-27 T 28-03-2018 CNX65_RS23590 b677e8da5f79133d7fd38c127c1a9839 275 Pfam PF03537 Glycoside-hydrolase family GH114 45 260 1.9E-47 T 28-03-2018 IPR004352 Glycoside-hydrolase family GH114, TIM-barrel domain CNX65_RS23590 b677e8da5f79133d7fd38c127c1a9839 275 Gene3D G3DSA:3.20.20.70 57 260 7.9E-27 T 28-03-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 CNX65_RS25390 2c7bc3c1316f442fc02fa0c04fde3fa1 687 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 132 504 1.3E-83 T 28-03-2018 IPR026337 HEXXH motif domain CNX65_RS34945 2d571d1a1fc01e83cd5720246fdb39a7 176 Pfam PF13630 SdpI/YhfL protein family 70 136 1.1E-9 T 28-03-2018 IPR025962 SdpI/YhfL protein family CNX65_RS34360 74c710b00e7e2120013dfef5aa807a0a 126 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 114 2.6E-28 T 28-03-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV CNX65_RS04080 fe9f551e23fbd6029bd490fe28feb218 114 Pfam PF16170 Domain of unknown function (DUF4873) 24 112 2.5E-34 T 28-03-2018 IPR032371 Domain of unknown function DUF4873 CNX65_RS11470 386071a8764904721f34813749e9b723 300 Gene3D G3DSA:3.40.50.10330 1 129 1.3E-25 T 28-03-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, domain 1 GO:0003951|GO:0008152 CNX65_RS11470 386071a8764904721f34813749e9b723 300 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 124 4.8E-21 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CNX65_RS11470 386071a8764904721f34813749e9b723 300 SUPERFAMILY SSF111331 3 286 5.01E-62 T 28-03-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain CNX65_RS11470 386071a8764904721f34813749e9b723 300 SMART SM00046 3 124 5.9E-5 T 28-03-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 CNX65_RS06570 a57d6009f9241e8ceeae6d867eb16d4c 217 Pfam PF04973 Nicotinamide mononucleotide transporter 18 196 1.9E-40 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CNX65_RS06570 a57d6009f9241e8ceeae6d867eb16d4c 217 TIGRFAM TIGR01528 NMN_trans_PnuC: nicotinamide mononucleotide transporter PnuC 18 199 4.7E-12 T 28-03-2018 IPR006419 Nicotinamide mononucleotide transporter PnuC GO:0016020|GO:0034257|GO:0034258 CNX65_RS07515 a7497921f87d18319167162c3a41cbfb 267 Gene3D G3DSA:3.40.50.1820 4 238 2.2E-13 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07515 a7497921f87d18319167162c3a41cbfb 267 SUPERFAMILY SSF53474 41 127 5.84E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS07515 a7497921f87d18319167162c3a41cbfb 267 SUPERFAMILY SSF53474 158 232 5.84E-14 T 28-03-2018 IPR029058 Alpha/Beta hydrolase fold CNX65_RS21390 571305707ed98da05c6aa87a99929f71 780 Gene3D G3DSA:2.60.40.10 502 599 0.0029 T 28-03-2018 IPR013783 Immunoglobulin-like fold CNX65_RS21390 571305707ed98da05c6aa87a99929f71 780 SUPERFAMILY SSF49299 506 585 9.03E-5 T 28-03-2018 IPR000601 PKD domain CNX65_RS21525 bc5e515c215349853e64bc5b7514f29c 235 Gene3D G3DSA:3.30.1310.10 2 116 2.1E-6 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS31925 dafa00bceebb0aa4256ba7b9f75c5a86 233 Pfam PF17270 Family of unknown function (DUF5336) 6 134 2.9E-12 T 28-03-2018 IPR035166 Protein of unknown function DUF5336 CNX65_RS03445 4153cdf409219326a64b7d8a2efc95f5 547 Pfam PF05960 Bacterial protein of unknown function (DUF885) 20 537 8.7E-149 T 28-03-2018 IPR010281 Protein of unknown function DUF885 CNX65_RS17700 85f0cedd9811d8876774eb412db5c321 271 Gene3D G3DSA:1.10.1220.10 2 63 6.2E-4 T 28-03-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 CNX65_RS14780 8d1cd3c2ef5b8bb26a5688839d26974d 241 Pfam PF14065 Protein of unknown function (DUF4255) 4 180 1.3E-40 T 28-03-2018 IPR025351 Protein of unknown function DUF4255 CNX65_RS11790 7a9c51be96a5eb196b2d663a50809329 161 SUPERFAMILY SSF103039 41 116 1.7E-14 T 28-03-2018 IPR028976 CheC-like domain CNX65_RS11790 7a9c51be96a5eb196b2d663a50809329 161 Gene3D G3DSA:3.40.1550.10 7 153 4.6E-13 T 28-03-2018 IPR028976 CheC-like domain CNX65_RS11790 7a9c51be96a5eb196b2d663a50809329 161 Pfam PF13690 Chemotaxis phosphatase CheX 44 117 3.6E-16 T 28-03-2018 IPR028051 Chemotaxis phosphatase CheX-like domain CNX65_RS04770 17bacb822d4e1c83d8f39a722168f832 175 Pfam PF02592 Putative vitamin uptake transporter 83 159 1.9E-9 T 28-03-2018 IPR003744 Queuosine precursor transporter CNX65_RS06405 3e9f58e178836e43ae389c02e0a35047 127 Gene3D G3DSA:1.10.260.40 8 75 1.8E-7 T 28-03-2018 CNX65_RS05815 d3816352d8a1fdb28d4992bfff2b98b8 151 Pfam PF14017 Protein of unknown function (DUF4233) 20 123 7.6E-23 T 28-03-2018 IPR025327 Protein of unknown function DUF4233 CNX65_RS24440 5ca9048f71b511e8338b45883010c445 518 SUPERFAMILY SSF53756 11 368 2.13E-61 T 28-03-2018 CNX65_RS24440 5ca9048f71b511e8338b45883010c445 518 Gene3D G3DSA:3.40.50.2000 138 364 1.3E-39 T 28-03-2018 CNX65_RS24440 5ca9048f71b511e8338b45883010c445 518 Pfam PF13439 Glycosyltransferase Family 4 24 182 1.9E-14 T 28-03-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193 CNX65_RS24440 5ca9048f71b511e8338b45883010c445 518 Pfam PF00534 Glycosyl transferases group 1 195 326 2.1E-26 T 28-03-2018 IPR001296 Glycosyl transferase, family 1 CNX65_RS03415 32dfb8599cdd309ca9bfa46025f4522a 430 Pfam PF01882 Protein of unknown function DUF58 193 287 2.0E-18 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CNX65_RS03415 32dfb8599cdd309ca9bfa46025f4522a 430 Gene3D G3DSA:3.40.50.410 203 419 3.2E-15 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS02335 e3c12bdcb228a20e291938a26b9d96ef 248 Pfam PF05331 Protein of unknown function (DUF742) 136 248 2.4E-32 T 28-03-2018 IPR007995 Protein of unknown function DUF742 CNX65_RS22275 a293d4469003a11e33a7620137e9553d 390 Pfam PF14025 Protein of unknown function (DUF4241) 216 376 7.8E-36 T 28-03-2018 IPR025335 Protein of unknown function DUF4241 CNX65_RS21805 ec245053be46c78063ed950ebc3ff6cd 125 Gene3D G3DSA:3.10.180.10 1 125 9.2E-20 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS21805 ec245053be46c78063ed950ebc3ff6cd 125 SUPERFAMILY SSF54593 1 123 6.71E-16 T 28-03-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase CNX65_RS13130 7056cc170c325099b0924522e1264f97 147 SUPERFAMILY SSF160424 11 140 3.79E-24 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS01910 3f2b2187476762c51ef50be2ed173da1 464 Pfam PF06738 Putative threonine/serine exporter 37 279 1.5E-62 T 28-03-2018 IPR010619 Putative threonine/serine exporter CNX65_RS01910 3f2b2187476762c51ef50be2ed173da1 464 Pfam PF12821 Threonine/Serine exporter, ThrE 309 431 2.8E-17 T 28-03-2018 IPR024528 Threonine/Serine exporter, ThrE CNX65_RS09720 f9866a06208b103524c48f16ce5385bb 282 Gene3D G3DSA:3.40.50.150 3 270 9.2E-36 T 28-03-2018 CNX65_RS09720 f9866a06208b103524c48f16ce5385bb 282 Pfam PF08241 Methyltransferase domain 73 175 8.6E-6 T 28-03-2018 IPR013216 Methyltransferase type 11 GO:0008152|GO:0008168 CNX65_RS09720 f9866a06208b103524c48f16ce5385bb 282 SUPERFAMILY SSF53335 25 229 8.1E-31 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS19440 266cc7a3f72f213ed403cbd2f15256d1 181 Pfam PF01925 Sulfite exporter TauE/SafE 10 131 1.8E-13 T 28-03-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 CNX65_RS33930 3168d101fd56b9131c37c9f385780ce1 125 Gene3D G3DSA:3.30.1050.10 25 124 5.8E-4 T 28-03-2018 IPR003033 SCP2 sterol-binding domain CNX65_RS05125 461660aec2f607ed6f8922d9d91a99c4 319 SUPERFAMILY SSF52047 79 206 9.42E-6 T 28-03-2018 CNX65_RS05125 461660aec2f607ed6f8922d9d91a99c4 319 Gene3D G3DSA:3.80.10.10 71 279 5.5E-7 T 28-03-2018 IPR032675 Leucine-rich repeat domain, L domain-like CNX65_RS14710 1b3fe1c5d4bf7b879cd824cc4839e687 292 SUPERFAMILY SSF161098 23 292 3.4E-71 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14710 1b3fe1c5d4bf7b879cd824cc4839e687 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 103 283 7.5E-17 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS14710 1b3fe1c5d4bf7b879cd824cc4839e687 292 Gene3D G3DSA:1.10.3720.10 26 280 7.1E-40 T 28-03-2018 CNX65_RS12965 ec00c6e36176d2a9b145444873b912ce 186 Gene3D G3DSA:1.10.357.10 1 186 4.3E-34 T 28-03-2018 CNX65_RS12965 ec00c6e36176d2a9b145444873b912ce 186 SUPERFAMILY SSF48498 84 185 8.15E-14 T 28-03-2018 IPR011075 Tetracycline transcriptional regulator, TetR-related, C-terminal CNX65_RS12965 ec00c6e36176d2a9b145444873b912ce 186 SUPERFAMILY SSF46689 10 78 7.98E-15 T 28-03-2018 IPR009057 Homeobox domain-like GO:0003677 CNX65_RS12965 ec00c6e36176d2a9b145444873b912ce 186 Pfam PF00440 Bacterial regulatory proteins, tetR family 20 64 1.6E-9 T 28-03-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 CNX65_RS26935 9bbba094a299353941ecdd31229e5297 154 Gene3D G3DSA:2.80.10.50 6 145 3.1E-4 T 28-03-2018 CNX65_RS18445 adff435926e6f9b614c42cf345029fd6 162 Pfam PF14430 Immunity protein Imm1 40 152 1.3E-22 T 28-03-2018 IPR025680 Immunity protein Imm1 CNX65_RS31425 b52edf50a93edbc1472ef79497309273 197 Pfam PF12079 Protein of unknown function (DUF3558) 16 190 3.0E-23 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS11610 9ea1be03026910cd56ccea1662f499d1 236 SUPERFAMILY SSF51658 2 155 5.44E-14 T 28-03-2018 IPR013022 Xylose isomerase-like, TIM barrel domain CNX65_RS11610 9ea1be03026910cd56ccea1662f499d1 236 Gene3D G3DSA:3.20.20.150 2 161 4.1E-16 T 28-03-2018 CNX65_RS28110 b21211208b3871339486f7ad39cbecb1 166 Pfam PF10821 Protein of unknown function (DUF2567) 18 162 3.1E-10 T 28-03-2018 IPR021213 Protein of unknown function DUF2567 CNX65_RS18465 aaecab166ff26882579ee6e64d0180b3 185 Pfam PF03596 Cadmium resistance transporter 3 183 8.3E-26 T 28-03-2018 IPR004676 Cadmium resistance transporter CNX65_RS09365 cefeddf428a6566548fa8e622160ecfd 362 Gene3D G3DSA:1.10.10.10 243 348 1.1E-4 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11085 431c620e1775b20380fe5c5a399fdf58 325 SUPERFAMILY SSF161098 39 325 1.83E-50 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS11085 431c620e1775b20380fe5c5a399fdf58 325 Gene3D G3DSA:1.10.3720.10 96 319 1.2E-29 T 28-03-2018 CNX65_RS11085 431c620e1775b20380fe5c5a399fdf58 325 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 121 318 7.2E-11 T 28-03-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0006810|GO:0016020 CNX65_RS01155 dde2081f6cd83d623a46a3d48e11c5b7 275 Gene3D G3DSA:1.25.40.10 2 235 1.3E-4 T 28-03-2018 IPR011990 Tetratricopeptide-like helical domain GO:0005515 CNX65_RS20310 85fb5a3892472765a66e68d5f7ef3283 187 Gene3D G3DSA:3.10.450.50 12 156 3.3E-19 T 28-03-2018 CNX65_RS20310 85fb5a3892472765a66e68d5f7ef3283 187 Pfam PF07366 SnoaL-like polyketide cyclase 22 141 3.4E-14 T 28-03-2018 IPR009959 Polyketide cyclase SnoaL-like domain CNX65_RS20310 85fb5a3892472765a66e68d5f7ef3283 187 SUPERFAMILY SSF54427 14 142 1.4E-24 T 28-03-2018 IPR032710 NTF2-like domain CNX65_RS09645 3dd3f142305992c2b2473cf813d001b1 300 SUPERFAMILY SSF51735 1 267 1.0E-45 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09645 3dd3f142305992c2b2473cf813d001b1 300 Pfam PF13460 NAD(P)H-binding 7 118 3.5E-13 T 28-03-2018 IPR016040 NAD(P)-binding domain CNX65_RS09645 3dd3f142305992c2b2473cf813d001b1 300 Gene3D G3DSA:3.40.50.720 1 275 6.4E-31 T 28-03-2018 CNX65_RS01715 b15fcb265cd7c976ba1d94802add9949 271 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 247 267 2.7E-7 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CNX65_RS08260 21fe357bed277ded102c0d576f3a29a6 199 Pfam PF13644 DKNYY family 10 185 1.4E-5 T 28-03-2018 IPR027375 DKNYY family CNX65_RS11595 26cd07b3e70e4f9f0f0d01ade1e5d173 737 Gene3D G3DSA:3.90.176.10 514 705 3.0E-14 T 28-03-2018 CNX65_RS10685 1a08ba38f71e9df468739208e3d3d2d0 162 Pfam PF14024 Protein of unknown function (DUF4240) 48 122 1.4E-9 T 28-03-2018 IPR025334 Domain of unknown function (DUF4240 CNX65_RS29340 bca8cafb1a2bce77c59627cd108e3023 62 Pfam PF04149 Domain of unknown function (DUF397) 11 56 8.5E-11 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS13165 02b6f89666583fc46662f2ec3fd7c559 161 Pfam PF09438 Domain of unknown function (DUF2017) 56 120 9.5E-6 T 28-03-2018 IPR018561 Domain of unknown function DUF2017 CNX65_RS00430 60b1b5f0cf27033e423e3ffad2e33eff 237 Pfam PF02517 CAAX protease self-immunity 131 220 2.9E-14 T 28-03-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 CNX65_RS02560 8509cad434d0a3a280b7ee9df6b38a93 178 Pfam PF14016 Protein of unknown function (DUF4232) 43 175 3.5E-29 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CNX65_RS17425 6512b9a83b6aa57a2058efa1aec500b8 258 Pfam PF14428 SCP1.201-like deaminase 154 254 7.1E-16 T 28-03-2018 IPR032724 Deaminase, SCP1.201-like CNX65_RS23940 cf858e17de5585c4335fce56502454df 300 Pfam PF14100 Methane oxygenase PmoA 16 288 3.2E-72 T 28-03-2018 IPR029475 Methane oxygenase PmoA CNX65_RS06735 724c863cdd7b0fd46e67b1a9b2bcc360 137 Pfam PF14430 Immunity protein Imm1 14 128 1.6E-27 T 28-03-2018 IPR025680 Immunity protein Imm1 CNX65_RS12255 ec88c40a729fed7285dfbc1ab5b712d0 243 Gene3D G3DSA:3.40.109.10 84 227 3.8E-6 T 28-03-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 CNX65_RS14460 8b2742d0b5ce2d9fd8d2a0494a90552b 155 SUPERFAMILY SSF82607 31 107 5.36E-6 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS14460 8b2742d0b5ce2d9fd8d2a0494a90552b 155 Pfam PF02575 YbaB/EbfC DNA-binding family 31 107 8.8E-8 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS14460 8b2742d0b5ce2d9fd8d2a0494a90552b 155 Gene3D G3DSA:3.30.1310.10 13 111 1.1E-12 T 28-03-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family CNX65_RS07490 26f5b9a5d54f996b418e6481f67569df 235 Pfam PF13399 LytR cell envelope-related transcriptional attenuator 99 183 4.2E-7 T 28-03-2018 IPR027381 Putative LytR/CpsA/Psr regulator, C-terminal domain CNX65_RS00560 0f2b3b707ed898444c7c66da2375e241 342 Pfam PF13845 Septum formation 46 262 1.6E-67 T 28-03-2018 IPR026004 Septum formation-related domain CNX65_RS06745 7e2db04cdc04924be4b0dca73bae398e 212 Pfam PF11241 Protein of unknown function (DUF3043) 34 208 3.2E-59 T 28-03-2018 IPR021403 Protein of unknown function DUF3043 CNX65_RS08410 2b48e360e7fc9c2eab1765dccf6e8371 185 Gene3D G3DSA:3.60.15.10 4 172 4.2E-5 T 28-03-2018 IPR001279 Metallo-beta-lactamase CNX65_RS30120 acc547afd6e5d2e0955630c3cc5d31b4 61 Pfam PF04149 Domain of unknown function (DUF397) 10 61 3.2E-21 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS21185 5c4e0cda0ff220d903a7d8118db2057f 601 TIGRFAM TIGR04267 mod_HExxH: HEXXH motif domain 39 421 2.3E-92 T 28-03-2018 IPR026337 HEXXH motif domain CNX65_RS19325 ee386b6b3e2693bef92ef67c082ae414 150 Pfam PF10002 Predicted membrane protein (DUF2243) 7 136 8.8E-41 T 28-03-2018 IPR018719 Protein of unknown function DUF2243, membrane CNX65_RS14370 056a41676165407b960c3e80b572f6a3 306 Pfam PF00296 Luciferase-like monooxygenase 8 244 9.8E-44 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS14370 056a41676165407b960c3e80b572f6a3 306 SUPERFAMILY SSF51679 7 301 4.42E-54 T 28-03-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 CNX65_RS14370 056a41676165407b960c3e80b572f6a3 306 Gene3D G3DSA:3.20.20.30 258 305 0.044 T 28-03-2018 CNX65_RS14370 056a41676165407b960c3e80b572f6a3 306 Gene3D G3DSA:3.20.20.30 9 257 3.4E-53 T 28-03-2018 CNX65_RS19605 4c023a2cf1e09b82fd09c5222616f5e7 146 Gene3D G3DSA:3.40.1800.10 2 69 0.0036 T 28-03-2018 CNX65_RS08290 5d518407de529a5946455de4bf5c53ab 252 Pfam PF03707 Bacterial signalling protein N terminal repeat 59 115 1.9E-11 T 28-03-2018 IPR005330 MHYT domain CNX65_RS08290 5d518407de529a5946455de4bf5c53ab 252 Pfam PF03707 Bacterial signalling protein N terminal repeat 122 179 1.8E-16 T 28-03-2018 IPR005330 MHYT domain CNX65_RS08290 5d518407de529a5946455de4bf5c53ab 252 Pfam PF03707 Bacterial signalling protein N terminal repeat 184 242 9.3E-7 T 28-03-2018 IPR005330 MHYT domain CNX65_RS08700 ae48a3bca9ae31d042ab2c3f9447330a 472 Pfam PF13440 Polysaccharide biosynthesis protein 29 320 1.8E-74 T 28-03-2018 CNX65_RS29980 1dc80a23b94fc0711aa281e811d41f94 321 Gene3D G3DSA:3.40.50.2300 30 147 7.3E-22 T 28-03-2018 CNX65_RS29980 1dc80a23b94fc0711aa281e811d41f94 321 Pfam PF13407 Periplasmic binding protein domain 37 292 3.7E-51 T 28-03-2018 IPR025997 Periplasmic binding protein CNX65_RS29980 1dc80a23b94fc0711aa281e811d41f94 321 SUPERFAMILY SSF53822 33 312 2.04E-58 T 28-03-2018 IPR028082 Periplasmic binding protein-like I CNX65_RS29980 1dc80a23b94fc0711aa281e811d41f94 321 Gene3D G3DSA:3.40.50.2300 148 304 1.6E-33 T 28-03-2018 CNX65_RS00695 e0fa597939e468e5312d30914ab39c2d 547 Pfam PF15521 Novel toxin 11 256 500 3.3E-44 T 28-03-2018 IPR029121 Novel toxin 11 CNX65_RS12720 acf5c43793f6650444013d43e83963c3 284 Pfam PF13569 Domain of unknown function (DUF4132) 27 203 1.1E-28 T 28-03-2018 IPR025406 Domain of unknown function DUF4132 CNX65_RS12425 ccdd88cd6b3c9aabd3c09b13855867fa 196 Pfam PF01169 Uncharacterized protein family UPF0016 11 83 6.4E-21 T 28-03-2018 IPR001727 Gdt1 family CNX65_RS12425 ccdd88cd6b3c9aabd3c09b13855867fa 196 Pfam PF01169 Uncharacterized protein family UPF0016 113 183 4.5E-22 T 28-03-2018 IPR001727 Gdt1 family CNX65_RS33540 09c2fb60475505a3a9971c2ade3a0c1e 279 Pfam PF09995 Uncharacterized protein conserved in bacteria (DUF2236) 13 245 8.8E-44 T 28-03-2018 IPR018713 Domain of unknown function DUF2236 CNX65_RS19790 913ffdb313a7718ea656913e12d6d6ef 272 Gene3D G3DSA:1.20.5.620 199 263 3.7E-4 T 28-03-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain CNX65_RS22860 9af056def4dd95bf0aefdc3bf98400e6 235 Gene3D G3DSA:3.40.50.150 20 231 6.8E-16 T 28-03-2018 CNX65_RS22860 9af056def4dd95bf0aefdc3bf98400e6 235 SUPERFAMILY SSF53335 47 191 3.27E-14 T 28-03-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase CNX65_RS20845 c90c96e674f64e17dd61244d090f34d5 196 Gene3D G3DSA:3.50.30.40 11 180 3.7E-48 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CNX65_RS20845 c90c96e674f64e17dd61244d090f34d5 196 Pfam PF03737 Aldolase/RraA 16 162 8.5E-42 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CNX65_RS20845 c90c96e674f64e17dd61244d090f34d5 196 SUPERFAMILY SSF89562 14 172 1.16E-42 T 28-03-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein CNX65_RS30065 1894587b8a7ce3c5232806a28c5aa192 187 Pfam PF12079 Protein of unknown function (DUF3558) 15 184 1.1E-14 T 28-03-2018 IPR024520 Protein of unknown function DUF3558 CNX65_RS31310 359ec29963ccdb317619b209f1a357e8 139 Pfam PF14430 Immunity protein Imm1 13 125 3.7E-29 T 28-03-2018 IPR025680 Immunity protein Imm1 CNX65_RS34180 5ba8002cb0da2b6baf6a7b19b720cb8a 94 Pfam PF04248 Domain of unknown function (DUF427) 4 88 2.0E-31 T 28-03-2018 IPR007361 Domain of unknown function DUF427 CNX65_RS18350 98489c3f6fdfa5707a9789543795b86b 223 Pfam PF01184 GPR1/FUN34/yaaH family 25 202 1.7E-12 T 28-03-2018 IPR000791 Acetate transporter GPR1/FUN34/SatP family GO:0016021 CNX65_RS28305 71df325cd741866a307394c29fb33e0b 429 Gene3D G3DSA:3.40.50.410 207 380 2.5E-4 T 28-03-2018 IPR002035 von Willebrand factor, type A CNX65_RS28305 71df325cd741866a307394c29fb33e0b 429 Pfam PF01882 Protein of unknown function DUF58 197 280 1.5E-19 T 28-03-2018 IPR002881 Domain of unknown function DUF58 CNX65_RS27440 4bdb970d5fcc965ba7a36117ba588dbb 205 SUPERFAMILY SSF55073 22 140 8.01E-8 T 28-03-2018 IPR029787 Nucleotide cyclase CNX65_RS27440 4bdb970d5fcc965ba7a36117ba588dbb 205 Gene3D G3DSA:3.30.70.1230 20 195 5.2E-6 T 28-03-2018 IPR001054 Adenylyl cyclase class-3/4/guanylyl cyclase GO:0009190|GO:0016849|GO:0035556 CNX65_RS34400 a55639ac3e3bc50e81c39de8501fda43 528 Pfam PF00474 Sodium:solute symporter family 33 414 8.1E-26 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS11920 c380222caeaa1b23b9cb55ea26650195 672 Pfam PF02120 Flagellar hook-length control protein FliK 550 625 2.5E-13 T 28-03-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal CNX65_RS28150 715cbb64324cda3e601b93c3c0f12f02 289 Gene3D G3DSA:2.60.40.1240 153 282 1.8E-10 T 28-03-2018 IPR029050 Immunoprotective extracellular, immunoglobulin-like domain CNX65_RS16815 beb0c966713ff87021f750146076a2ef 87 Pfam PF04226 Transglycosylase associated protein 32 75 8.3E-6 T 28-03-2018 IPR007341 Transglycosylase-associated protein GO:0016021 CNX65_RS08415 4a675a5162f7ecfdd5f23138b43176d2 74 Gene3D G3DSA:1.10.10.10 1 25 0.39 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS08415 4a675a5162f7ecfdd5f23138b43176d2 74 Gene3D G3DSA:1.10.10.10 41 74 0.37 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS11270 790d7c4f250704c1641ea81f1dc112d6 225 Pfam PF11575 FhuF 2Fe-2S C-terminal domain 202 222 3.5E-10 T 28-03-2018 IPR024726 Ferric iron reductase, C-terminal GO:0051537 CNX65_RS00575 80e921d9b2c7172efc2c7719803a75b4 150 Pfam PF03994 Domain of Unknown Function (DUF350) 25 78 1.5E-13 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CNX65_RS00575 80e921d9b2c7172efc2c7719803a75b4 150 Pfam PF03994 Domain of Unknown Function (DUF350) 95 149 1.5E-12 T 28-03-2018 IPR007140 Protein of unknown function DUF350 CNX65_RS08315 b53320c4c7ca5c0eeb44986153cd6cbd 252 Pfam PF14023 Protein of unknown function (DUF4239) 48 242 2.5E-5 T 28-03-2018 IPR025333 Protein of unknown function DUF4239 CNX65_RS26345 16036cbbe193b0c81ff045d9453591c5 135 Gene3D G3DSA:3.30.1460.10 9 132 3.9E-8 T 28-03-2018 CNX65_RS16795 4b02c500acc8a5f61710a282b9c3e091 120 Gene3D G3DSA:2.30.30.240 9 91 8.9E-5 T 28-03-2018 CNX65_RS20855 0b08489f35a4a5b63ff92bea5c66e6cb 214 Gene3D G3DSA:3.40.1580.10 24 169 3.6E-5 T 28-03-2018 CNX65_RS29230 7a54e4811189bd4d92197176749d406b 273 Pfam PF13490 Putative zinc-finger 11 36 2.9E-7 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS12615 d07160d012b3c3e71ffbd888b6a7ad2a 136 Gene3D G3DSA:3.40.50.280 30 102 0.0014 T 28-03-2018 CNX65_RS01415 3dd12f4c2e9c84c6c0c79afb268ee297 721 Gene3D G3DSA:3.40.50.300 340 559 5.9E-5 T 28-03-2018 CNX65_RS34565 9624a46ed82e5b1cecb4e694ef01e32d 276 Pfam PF13845 Septum formation 52 254 5.0E-38 T 28-03-2018 IPR026004 Septum formation-related domain CNX65_RS34285 b140693828c85d8e311d810d53b1e7f5 305 Gene3D G3DSA:1.10.287.1060 60 150 2.0E-9 T 28-03-2018 CNX65_RS34285 b140693828c85d8e311d810d53b1e7f5 305 SUPERFAMILY SSF140453 64 114 2.35E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS09155 5d3232945a82abfd0c718fc1a656a7e0 77 Pfam PF16827 zinc-finger 2 61 7.8E-18 T 28-03-2018 IPR031795 Putative zinc-finger containing protein CNX65_RS14375 8bbb367a267451dbeefe8b152f8097c9 628 Pfam PF02538 Hydantoinase B/oxoprolinase 5 534 4.6E-137 T 28-03-2018 IPR003692 Hydantoinase B/oxoprolinase GO:0003824 Reactome: R-HSA-174403 CNX65_RS31440 7957a8e882189e7c7524c80b505ee3fc 268 Pfam PF14011 EspG family 20 261 2.6E-67 T 28-03-2018 IPR025734 EspG family CNX65_RS23955 fafe0862a7f747cf2bb89693c72f7429 242 Gene3D G3DSA:1.10.3630.10 15 241 1.3E-30 T 28-03-2018 CNX65_RS23955 fafe0862a7f747cf2bb89693c72f7429 242 Pfam PF05719 Golgi phosphoprotein 3 (GPP34) 22 220 3.8E-42 T 28-03-2018 IPR008628 Golgi phosphoprotein 3-like GO:0070273 CNX65_RS08080 797b7573342de4b7db9f88c659ce8f83 329 Pfam PF01040 UbiA prenyltransferase family 75 285 1.0E-20 T 28-03-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 CNX65_RS29600 f810b02a9d2f6f2b90cd565c9bbf6921 89 Pfam PF04149 Domain of unknown function (DUF397) 23 81 3.4E-13 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS05045 0d89089f3667ade9a968e0a0be75b92a 185 Pfam PF09438 Domain of unknown function (DUF2017) 6 184 7.3E-62 T 28-03-2018 IPR018561 Domain of unknown function DUF2017 CNX65_RS12325 c73231ab5a088cb98cb9832c41e80b59 269 Gene3D G3DSA:1.10.287.70 12 225 5.5E-44 T 28-03-2018 CNX65_RS12325 c73231ab5a088cb98cb9832c41e80b59 269 Pfam PF00520 Ion transport protein 15 223 8.0E-44 T 28-03-2018 IPR005821 Ion transport domain GO:0005216|GO:0006811|GO:0016020|GO:0055085 CNX65_RS12325 c73231ab5a088cb98cb9832c41e80b59 269 SUPERFAMILY SSF81324 14 223 2.94E-33 T 28-03-2018 CNX65_RS26735 53389c3b5164c4c14cc45df0b0334d5b 239 Pfam PF13490 Putative zinc-finger 12 41 1.4E-8 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS21740 297aef1bb4de1ac9edc399643e70f32a 250 Gene3D G3DSA:1.10.1780.10 95 250 1.2E-8 T 28-03-2018 IPR004176 Clp, N-terminal GO:0019538 CNX65_RS06315 9c2f85a54c3565839b831dcd14cda21b 485 Pfam PF00916 Sulfate permease family 27 382 2.0E-58 T 28-03-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 CNX65_RS28215 5366789a505cce11a7f4596d8506eb4c 215 Pfam PF04472 Cell division protein SepF 127 198 3.0E-27 T 28-03-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 CNX65_RS28215 5366789a505cce11a7f4596d8506eb4c 215 Hamap MF_01197 Cell division protein SepF [sepF]. 1 206 21.9 T 28-03-2018 IPR023052 Cell division protein SepF GO:0090529 CNX65_RS32265 08e79f8787376b5e0844a86ccdbdcd1f 114 Gene3D G3DSA:1.10.287.1060 10 106 2.1E-9 T 28-03-2018 CNX65_RS28210 fc337467d9cd4b46371642877fbc4fb2 94 Pfam PF02325 YGGT family 10 90 4.0E-12 T 28-03-2018 IPR003425 CCB3/YggT GO:0016020 CNX65_RS21440 4f6a9b8d9bdf98614f916b0ca8f8dc20 254 Gene3D G3DSA:1.10.10.10 1 84 2.2E-5 T 28-03-2018 IPR011991 Winged helix-turn-helix DNA-binding domain CNX65_RS26535 c59c1305e035a7da84048031eb41e1ca 205 Pfam PF14014 Protein of unknown function (DUF4230) 47 197 6.8E-30 T 28-03-2018 IPR025324 Protein of unknown function DUF4230 CNX65_RS12945 770fa1ec8c01e500fb3fcc2206fa0c07 171 Pfam PF14317 YcxB-like protein 95 153 3.8E-10 T 28-03-2018 IPR025588 YcxB-like protein CNX65_RS00540 aa5e3476cde5ed10575f896bc19f26d9 61 Pfam PF04149 Domain of unknown function (DUF397) 3 54 1.0E-17 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS15150 ce9259fdc1ddd2ff90b6e2dd06cf67b1 382 SUPERFAMILY SSF53649 40 380 5.23E-52 T 28-03-2018 IPR017850 Alkaline-phosphatase-like, core domain GO:0003824|GO:0008152 CNX65_RS15150 ce9259fdc1ddd2ff90b6e2dd06cf67b1 382 Gene3D G3DSA:3.40.720.10 32 381 3.6E-26 T 28-03-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824|GO:0008152 CNX65_RS15150 ce9259fdc1ddd2ff90b6e2dd06cf67b1 382 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 41 367 1.2E-28 T 28-03-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 CNX65_RS33915 bf37fa008064225f04d184afc488c5c0 104 Pfam PF10824 Excreted virulence factor EspC, type VII ESX diderm 4 95 2.3E-5 T 28-03-2018 IPR022536 ESX-1 secretion-associated protein EspC GO:0009306 CNX65_RS33915 bf37fa008064225f04d184afc488c5c0 104 Gene3D G3DSA:1.10.287.1060 1 98 1.7E-8 T 28-03-2018 CNX65_RS16315 c875ac8bb46ad28bf45e4183b7d4edd9 154 Pfam PF14325 Domain of unknown function (DUF4383) 13 138 9.1E-45 T 28-03-2018 IPR025492 Protein of unknown function DUF4383 CNX65_RS01080 0cd71cd258cf3e67450de52a62a7e72a 197 Gene3D G3DSA:1.10.287.1060 9 89 0.0077 T 28-03-2018 CNX65_RS26840 c82929e815be78561ef6c9734157aa86 147 TIGRFAM TIGR02241 TIGR02241: conserved hypothetical phage tail region protein 9 146 3.6E-32 T 28-03-2018 IPR011747 Conserved hypothetical protein CHP02241 CNX65_RS26840 c82929e815be78561ef6c9734157aa86 147 Pfam PF06841 T4-like virus tail tube protein gp19 12 145 8.3E-30 T 28-03-2018 IPR010667 Bacteriophage T4, Gp19, tail tube GO:0005198 CNX65_RS32485 448061e2d2fd30301a234af1a7366988 106 Gene3D G3DSA:1.10.287.1060 2 103 4.1E-15 T 28-03-2018 CNX65_RS32485 448061e2d2fd30301a234af1a7366988 106 SUPERFAMILY SSF140453 5 101 3.79E-6 T 28-03-2018 IPR010310 Type VII secretion system ESAT-6-like CNX65_RS33825 1c4390902acb93eb907cb1dfc7c32b87 60 Pfam PF11273 Protein of unknown function (DUF3073) 2 59 2.3E-23 T 28-03-2018 IPR021426 Protein of unknown function DUF3073 CNX65_RS00360 c492f3d37af7b9135fced1c02894d8f8 603 Pfam PF00474 Sodium:solute symporter family 35 199 5.7E-23 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS00360 c492f3d37af7b9135fced1c02894d8f8 603 Pfam PF00474 Sodium:solute symporter family 308 504 2.5E-15 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS00380 275fb8649f04db54065dd5444356db0b 302 Pfam PF14219 Domain of unknown function (DUF4328) 107 265 2.2E-36 T 28-03-2018 IPR025565 Domain of unknown function DUF4328 CNX65_RS33935 d47cb2e0e01402817f700cc650638084 272 Pfam PF14011 EspG family 16 257 9.1E-70 T 28-03-2018 IPR025734 EspG family CNX65_RS13470 dad8124b420febcf18d40d10b7dee594 79 SUPERFAMILY SSF47336 2 75 1.44E-10 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13470 dad8124b420febcf18d40d10b7dee594 79 Pfam PF00550 Phosphopantetheine attachment site 6 72 3.8E-6 T 28-03-2018 IPR009081 Phosphopantetheine binding ACP domain CNX65_RS13470 dad8124b420febcf18d40d10b7dee594 79 Gene3D G3DSA:1.10.1200.10 1 77 9.0E-11 T 28-03-2018 CNX65_RS15490 02f33f06fe3e1141298ad5cb0712d8ba 218 Pfam PF09335 SNARE associated Golgi protein 44 172 2.3E-22 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS30775 2069c83205ae7d027577fee3a3f6a44c 291 Pfam PF12679 ABC-2 family transporter protein 6 290 7.2E-7 T 28-03-2018 IPR032688 ABC-2 family transporter protein GO:0006810 CNX65_RS05670 dbb6e45bec9155c8a06a7b6bb3a85959 165 Gene3D G3DSA:2.60.120.10 102 162 0.057 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS05670 dbb6e45bec9155c8a06a7b6bb3a85959 165 Gene3D G3DSA:2.60.120.10 4 101 0.089 T 28-03-2018 IPR014710 RmlC-like jelly roll fold CNX65_RS22960 6cf8d9bd66f8693f47d4cc3c1dbbdef2 110 Pfam PF03780 Asp23 family, cell envelope-related function 1 97 3.9E-11 T 28-03-2018 IPR005531 Alkaline shock protein Asp23 CNX65_RS00760 0f6cb869c36463ebd4c4977c8a338c3f 252 Pfam PF14011 EspG family 10 245 1.0E-48 T 28-03-2018 IPR025734 EspG family CNX65_RS00830 caa2a658857efa8895b34cf6a433cf13 57 Pfam PF14013 MT0933-like antitoxin protein 8 53 1.4E-12 T 28-03-2018 IPR028037 Antitoxin Rv0909/MT0933 CNX65_RS01660 d72b7cd13d51adbed378cdd3a58691f4 448 Pfam PF13367 Protease prsW family 77 273 4.0E-51 T 28-03-2018 IPR026898 Protease PrsW GO:0008233 CNX65_RS10130 e09bf2cf1cba445fdfaebdec025ad809 274 Gene3D G3DSA:3.20.20.105 13 240 2.7E-7 T 28-03-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 CNX65_RS15240 f71c875dc177e3954e2e710c27c7a02d 303 Pfam PF01145 SPFH domain / Band 7 family 29 199 3.9E-6 T 28-03-2018 IPR001107 Band 7 domain CNX65_RS32280 9e6f0b902277bf1f3a03ccfd9089ffbc 241 Gene3D G3DSA:3.40.50.720 50 207 5.0E-4 T 28-03-2018 CNX65_RS15920 5168eb776c2ab6f8ae5bc2e3b4238931 390 Pfam PF01757 Acyltransferase family 15 354 2.0E-31 T 28-03-2018 IPR002656 Acyltransferase 3 GO:0016747 CNX65_RS26045 c6895a59b2c8408f425746e785f5595b 131 Pfam PF13396 Phospholipase_D-nuclease N-terminal 72 114 3.0E-8 T 28-03-2018 IPR027379 Cardiolipin synthase N-terminal CNX65_RS12585 17be9e50f6b7ebdc9deb1c3368639b03 736 TIGRFAM TIGR04215 choice_anch_A: choice-of-anchor A domain 146 445 7.3E-33 T 28-03-2018 IPR026588 Choice-of-anchor A domain CNX65_RS13660 8f9a59cd4ce5ce71efc575e8e7c7c68f 855 Pfam PF02687 FtsX-like permease family 757 847 2.8E-9 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS13660 8f9a59cd4ce5ce71efc575e8e7c7c68f 855 Pfam PF02687 FtsX-like permease family 300 396 8.8E-15 T 28-03-2018 IPR003838 ABC transporter permease protein domain GO:0016020 CNX65_RS02885 87115db4ab9c6215ef3bb64c9681d19b 78 Pfam PF04149 Domain of unknown function (DUF397) 18 69 2.5E-18 T 28-03-2018 IPR007278 Domain of unknown function DUF397 CNX65_RS32010 112472b7627310e0c58d36085ad455a4 136 Pfam PF04686 Streptomyces sporulation and cell division protein, SsgA 24 119 1.6E-29 T 28-03-2018 IPR006776 Sporulation-specific cell division protein SsgB GO:0051301 CNX65_RS16790 37109067b4082dc7e603af0e1e86be61 325 Pfam PF01566 Natural resistance-associated macrophage protein 5 293 1.0E-35 T 28-03-2018 IPR001046 NRAMP family GO:0005215|GO:0006810|GO:0016020 Reactome: R-HSA-425410 CNX65_RS30900 bb89155d06902852d6e1288dba4941ed 412 Gene3D G3DSA:1.10.287.850 82 169 7.5E-9 T 28-03-2018 CNX65_RS30900 bb89155d06902852d6e1288dba4941ed 412 Gene3D G3DSA:1.10.287.850 290 390 0.015 T 28-03-2018 CNX65_RS13120 076e8408e991fae3d6a3cc484fdc4325 144 SUPERFAMILY SSF160424 11 140 8.5E-27 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS03465 821c98dd57f248f2fe4763427c81536d 455 Gene3D G3DSA:2.60.40.810 271 424 4.0E-12 T 28-03-2018 CNX65_RS22545 e47641fbee9e15fd73a728e4246eb569 419 Gene3D G3DSA:3.30.470.20 131 353 1.7E-14 T 28-03-2018 CNX65_RS22545 e47641fbee9e15fd73a728e4246eb569 419 SUPERFAMILY SSF56059 137 324 4.52E-12 T 28-03-2018 CNX65_RS06565 1f434013079d2f1ba862e983fd8893ca 297 Pfam PF05552 Conserved TM helix 11 55 4.6E-12 T 28-03-2018 IPR008910 Conserved TM helix CNX65_RS02785 2a845a7ad1aaa2530e284b4db1e806ca 159 Pfam PF14011 EspG family 14 126 1.2E-7 T 28-03-2018 IPR025734 EspG family CNX65_RS14740 fba00c9a5eb957ac5fd2800423a43979 412 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 123 399 5.3E-29 T 28-03-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD CNX65_RS24205 c72cedc0c580eb18164863de838d6c66 222 SUPERFAMILY SSF160631 2 111 1.44E-11 T 28-03-2018 CNX65_RS24205 c72cedc0c580eb18164863de838d6c66 222 Gene3D G3DSA:3.40.1580.10 3 215 8.0E-14 T 28-03-2018 CNX65_RS07415 08dc7f7a0302e64bc097f9f46b7f368d 108 Pfam PF11298 Protein of unknown function (DUF3099) 16 84 2.0E-31 T 28-03-2018 IPR021449 Protein of unknown function DUF3099 CNX65_RS03670 754a30b140f19594148e0953908a6bd4 226 Pfam PF14016 Protein of unknown function (DUF4232) 101 205 8.1E-19 T 28-03-2018 IPR025326 Protein of unknown function DUF4232 CNX65_RS06920 91cec2fed2c94d3f77ce7570d9e7259e 486 Pfam PF09594 Glycosyltransferase family 87 183 408 9.4E-5 T 28-03-2018 IPR018584 Glycosyltransferase family 87 GO:0016758 CNX65_RS06510 9ecc984eee0f34d8679594bcafb81796 167 Pfam PF11343 Protein of unknown function (DUF3145) 10 165 4.7E-73 T 28-03-2018 IPR021491 Protein of unknown function DUF3145 CNX65_RS14035 06c63efb4475bdc274008f6ec0380684 242 Pfam PF13490 Putative zinc-finger 3 37 8.2E-8 T 28-03-2018 IPR027383 Putative zinc-finger CNX65_RS34340 8d0637baa4d810fe9f840ca9f930d843 268 Pfam PF13349 Putative adhesin 121 263 1.5E-8 T 28-03-2018 IPR025164 Putative adhesin CNX65_RS16625 dde14e5b1206f313d2cceaa2a341ea04 144 Gene3D G3DSA:3.60.40.10 1 74 6.5E-6 T 28-03-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 CNX65_RS31430 afc73b31d3aa1e83d792fc9d2c031429 126 Gene3D G3DSA:1.10.287.1060 19 122 1.0E-4 T 28-03-2018 CNX65_RS32885 28ae84f410a24cfb576e1974236f3205 277 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 37 185 3.2E-34 T 28-03-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 CNX65_RS32885 28ae84f410a24cfb576e1974236f3205 277 Gene3D G3DSA:1.20.1250.20 2 213 0.0013 T 28-03-2018 CNX65_RS22535 7e9a9295d9ae7713d18b474b25bcef2e 353 Gene3D G3DSA:3.40.50.2000 53 345 1.9E-11 T 28-03-2018 CNX65_RS30315 ef1e9737210be3f469b576e83f147137 289 Pfam PF11303 Protein of unknown function (DUF3105) 92 218 6.2E-43 T 28-03-2018 IPR021454 Protein of unknown function DUF3105 CNX65_RS23850 e036aecc3f9517b5336402661dee6de6 237 Pfam PF09335 SNARE associated Golgi protein 28 145 2.3E-12 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS14475 1f27eaa42877605cb3918a9d828baf58 524 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 293 475 1.9E-15 T 28-03-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system CNX65_RS22360 b58cd628a67973927e8a7a3b94dca5c6 659 Pfam PF16861 Carbamoyltransferase C-terminus 398 551 3.2E-52 T 28-03-2018 IPR031730 Carbamoyltransferase, C-terminal CNX65_RS13875 832ad7110a8fef80528e1d18b8ef8ce3 159 Pfam PF11188 Protein of unknown function (DUF2975) 35 159 7.2E-32 T 28-03-2018 IPR021354 Protein of unknown function DUF2975 CNX65_RS18595 dbdd5d4c6f6d51efc66c68ee185893ad 195 Pfam PF04186 FxsA cytoplasmic membrane protein 13 119 2.6E-29 T 28-03-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 CNX65_RS04750 d9616778778e763fcbfb92f132b822bd 247 Pfam PF12315 Protein DA1 83 187 1.2E-12 T 28-03-2018 IPR022087 Protein DA1-like CNX65_RS11290 72f67698773ac6e1a695e81ede35d150 148 SUPERFAMILY SSF55729 21 121 3.29E-6 T 28-03-2018 IPR016181 Acyl-CoA N-acyltransferase CNX65_RS11290 72f67698773ac6e1a695e81ede35d150 148 Gene3D G3DSA:3.40.630.30 10 139 2.4E-7 T 28-03-2018 CNX65_RS25195 68f2b9fa84d647c18c7c5391287dc59d 82 Pfam PF13443 Cro/C1-type HTH DNA-binding domain 12 72 1.0E-4 T 28-03-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 CNX65_RS15010 fc970212c4eb3dd719cbd3c0f2302a92 183 Pfam PF10756 Bacterial PH domain 68 117 1.5E-4 T 28-03-2018 IPR019692 Protein of unknown function DUF2581 CNX65_RS17675 c9e0016aa088bd713390f15a2c97d4e1 357 Pfam PF06224 Winged helix DNA-binding domain 31 347 2.4E-66 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CNX65_RS34885 3268720deda17eb7760b3935c71b255b 199 Pfam PF08044 Domain of unknown function (DUF1707) 7 59 5.7E-20 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CNX65_RS28530 1cdee9a9640e17f4d440218c4eed1e82 403 Pfam PF06224 Winged helix DNA-binding domain 37 379 2.1E-73 T 28-03-2018 IPR009351 Protein of unknown function DUF1006 CNX65_RS24800 b3508dd2762333a3b1a5dfc3bc6e0313 158 Pfam PF06803 Protein of unknown function (DUF1232) 97 128 6.2E-12 T 28-03-2018 IPR010652 Protein of unknown function DUF1232 CNX65_RS11745 5444498dab98dc3379d5ac0689dcbce6 185 PRINTS PR01217 Proline rich extensin signature 3 19 8.9E-9 T 28-03-2018 CNX65_RS11745 5444498dab98dc3379d5ac0689dcbce6 185 PRINTS PR01217 Proline rich extensin signature 51 72 8.9E-9 T 28-03-2018 CNX65_RS11745 5444498dab98dc3379d5ac0689dcbce6 185 PRINTS PR01217 Proline rich extensin signature 146 171 8.9E-9 T 28-03-2018 CNX65_RS11745 5444498dab98dc3379d5ac0689dcbce6 185 PRINTS PR01217 Proline rich extensin signature 81 97 8.9E-9 T 28-03-2018 CNX65_RS15550 ab935b3e9e47ffa9383691a8970a79cf 127 Gene3D G3DSA:2.30.30.410 28 124 2.3E-5 T 28-03-2018 CNX65_RS25110 5fe3c1858580b19922c37fa4da557a51 210 Gene3D G3DSA:1.20.1170.10 14 193 7.8E-5 T 28-03-2018 CNX65_RS31095 47ab9116ce7058fba0ff0dc2ceb7189e 302 Gene3D G3DSA:1.10.260.40 6 78 2.4E-5 T 28-03-2018 CNX65_RS05150 82e8056e645715be84943b2ed70cc4e0 306 Pfam PF09335 SNARE associated Golgi protein 22 148 1.4E-21 T 28-03-2018 IPR032816 SNARE associated Golgi protein CNX65_RS21135 ac77a3f3dc6b94b17b67948f9e39f770 299 Gene3D G3DSA:1.10.287.850 81 256 1.6E-8 T 28-03-2018 CNX65_RS31370 89a088ceb3f5d778acb02e701bb6a31e 170 Pfam PF03703 Bacterial PH domain 78 151 2.6E-17 T 28-03-2018 IPR005182 Domain of unknown function DUF304 CNX65_RS25735 4cc6ac33a3c7109bf49c75ff1865d182 525 Pfam PF00474 Sodium:solute symporter family 36 445 3.4E-86 T 28-03-2018 IPR001734 Sodium/solute symporter GO:0005215|GO:0006810|GO:0016020|GO:0055085 CNX65_RS24450 063fc846d1b4bb081495e7350b75f04a 496 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 78 220 1.3E-8 T 28-03-2018 CNX65_RS10360 595c72ddb87a9f7e6b06bc889270eb8c 184 Pfam PF14280 Domain of unknown function (DUF4365) 26 177 2.1E-15 T 28-03-2018 IPR025375 Domain of unknown function DUF4365 CNX65_RS03525 ff1d8828b21fd16b3712d1af89fa5cda 139 Pfam PF14155 Domain of unknown function (DUF4307) 20 128 5.4E-31 T 28-03-2018 IPR025443 Protein of unknown function DUF4307 CNX65_RS33595 8d8a8a0e9bc9899bc3fc68dfd04e3f90 460 SUPERFAMILY SSF52540 188 442 9.03E-6 T 28-03-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase CNX65_RS05495 703bec2ce73ad6eac1492bb6a1c41b35 215 Pfam PF07510 Protein of unknown function (DUF1524) 116 210 6.6E-11 T 28-03-2018 IPR011089 Domain of unknown function DUF1524 CNX65_RS14190 5fcfdb001c0dc7d42d46306943e39986 1006 Gene3D G3DSA:3.30.360.10 2 238 8.9E-5 T 28-03-2018 CNX65_RS31875 d8151d0b1fd1af76394397dbdff2b958 156 SUPERFAMILY SSF160424 13 151 1.7E-18 T 28-03-2018 IPR006728 Protein of unknown function DUF600 CNX65_RS33120 7ba3f77f5011623adad59f02450b625b 147 Pfam PF11292 Protein of unknown function (DUF3093) 7 101 2.1E-5 T 28-03-2018 IPR021443 Protein of unknown function DUF3093 CNX65_RS29355 174a142b74753e8fc14e291774349f7a 275 Gene3D G3DSA:3.40.190.10 2 272 4.9E-5 T 28-03-2018 CNX65_RS25670 cf2afcc7a8577a49c1a2b6dd0ed5a7d6 203 Pfam PF06197 Protein of unknown function (DUF998) 13 194 1.4E-25 T 28-03-2018 IPR009339 Protein of unknown function DUF998 CNX65_RS32335 643434b507dbd77eb73edc643fad44b7 182 Pfam PF08044 Domain of unknown function (DUF1707) 34 86 2.1E-20 T 28-03-2018 IPR012551 Protein of unknown function DUF1707 CNX65_RS34450 fdc4cbd380d22a9ca06a1a0f37a4a8ef 221 Pfam PF04402 Protein of unknown function (DUF541) 20 217 1.9E-28 T 28-03-2018 IPR007497 Protein of unknown function DUF541