locus-tag	class	description
AEQU_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AEQU_RS00010	COG0706	membrane insertase activity
AEQU_RS00015	COG1847	R3H domain protein
AEQU_RS00020	COG0357	Ribosomal RNA small subunit methyltransferase G
AEQU_RS00030	COG1192	Involved in chromosome partitioning
AEQU_RS00035	COG1475	DNA binding
AEQU_RS00040	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AEQU_RS00045	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEQU_RS00055	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AEQU_RS00055	COG1199	ATP-dependent helicase activity
AEQU_RS00080	COG0629	single-stranded DNA binding
AEQU_RS00085	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AEQU_RS00090	COG0359	binds to the 23S rRNA
AEQU_RS00095	COG0305	Participates in initiation and elongation during chromosome replication
AEQU_RS00105	COG4717	serine-type aminopeptidase activity
AEQU_RS00115	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AEQU_RS00125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQU_RS00140	COG0622	Phosphoesterase
AEQU_RS00145	COG3706	GGDEF domain
AEQU_RS00155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AEQU_RS00160	COG0531	amino acid
AEQU_RS00185	COG1396	sequence-specific DNA binding
AEQU_RS00190	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_RS00195	COG0778	Nitroreductase
AEQU_RS00200	COG0346	lactoylglutathione lyase activity
AEQU_RS00210	COG1192	Involved in chromosome partitioning
AEQU_RS00215	COG1475	DNA binding
AEQU_RS00230	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEQU_RS00245	COG0270	DNA (cytosine-5-)-methyltransferase activity
AEQU_RS00315	COG4166	transmembrane transport
AEQU_RS00355	COG3433	isochorismatase activity
AEQU_RS00355	COG2226	methyltransferase
AEQU_RS00355	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AEQU_RS00360	COG3433	isochorismatase activity
AEQU_RS00360	COG2226	methyltransferase
AEQU_RS00360	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AEQU_RS00365	COG1021	2,3-dihydroxybenzoate-AMP ligase
AEQU_RS00380	COG1132	(ABC) transporter
AEQU_RS00390	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AEQU_RS00400	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AEQU_RS00410	COG2337	Toxic component of a toxin-antitoxin (TA) module
AEQU_RS00440	COG1012	belongs to the aldehyde dehydrogenase family
AEQU_RS00450	COG0546	phosphoglycolate phosphatase activity
AEQU_RS00460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AEQU_RS00490	COG0864	Transcriptional regulator
AEQU_RS00525	COG0443	Heat shock 70 kDa protein
AEQU_RS00530	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEQU_RS00535	COG0484	heat shock protein binding
AEQU_RS00540	COG0789	Transcriptional regulator
AEQU_RS00545	COG0542	response to heat
AEQU_RS00555	COG0393	Putative heavy-metal-binding
AEQU_RS00565	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AEQU_RS00570	COG3279	Response regulator of the LytR AlgR family
AEQU_RS00575	COG0166	Belongs to the GPI family
AEQU_RS00580	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AEQU_RS00585	COG0298	carbon dioxide binding
AEQU_RS00610	COG2801	Transposase and inactivated derivatives
AEQU_RS00620	COG1610	YqeY-like protein
AEQU_RS00625	COG0577	efflux transmembrane transporter activity
AEQU_RS00630	COG1136	(ABC) transporter
AEQU_RS00635	COG2205	protein histidine kinase activity
AEQU_RS00660	COG3428	Bacterial PH domain
AEQU_RS00665	COG4535	Mg2 and Co2 transporter CorC
AEQU_RS00675	COG0569	domain protein
AEQU_RS00695	COG1115	amino acid carrier protein
AEQU_RS00700	COG1763	Mo-molybdopterin cofactor biosynthetic process
AEQU_RS00710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEQU_RS00715	COG0765	amino acid transport
AEQU_RS00720	COG1126	abc transporter atp-binding protein
AEQU_RS00725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEQU_RS00730	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AEQU_RS00740	COG3655	Transcriptional regulator
AEQU_RS00755	COG0528	UMP kinase activity
AEQU_RS00760	COG0233	cytoplasmic translational termination
AEQU_RS00770	COG4589	Belongs to the CDS family
AEQU_RS00775	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AEQU_RS00785	COG0750	zinc metalloprotease
AEQU_RS00790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AEQU_RS00795	COG0442	prolyl-tRNA aminoacylation
AEQU_RS00810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEQU_RS00820	COG3620	sequence-specific DNA binding
AEQU_RS00845	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEQU_RS00850	COG2197	response regulator
AEQU_RS00875	COG0542	response to heat
AEQU_RS00910	COG0745	RESPONSE REGULATOR receiver
AEQU_RS00915	COG5002	protein histidine kinase activity
AEQU_RS00925	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS00935	COG1136	(ABC) transporter
AEQU_RS00965	COG0243	molybdopterin cofactor binding
AEQU_RS00970	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS00975	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS00980	COG3381	protein complex oligomerization
AEQU_RS00995	COG1053	succinate dehydrogenase
AEQU_RS00995	COG3976	FMN-binding domain protein
AEQU_RS01025	COG1410	methionine synthase
AEQU_RS01025	COG0646	methionine synthase
AEQU_RS01045	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEQU_RS01050	COG0402	S-adenosylhomocysteine deaminase activity
AEQU_RS01060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AEQU_RS01065	COG0085	RNA polymerase activity
AEQU_RS01070	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AEQU_RS01075	COG0583	DNA-binding transcription factor activity
AEQU_RS01135	COG0140	phosphoribosyl-ATP diphosphatase activity
AEQU_RS01140	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AEQU_RS01155	COG0733	neurotransmitter:sodium symporter activity
AEQU_RS01170	COG2076	Multidrug Resistance protein
AEQU_RS01190	COG0243	molybdopterin cofactor binding
AEQU_RS01195	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS01245	COG2326	polyphosphate kinase activity
AEQU_RS01255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AEQU_RS01265	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AEQU_RS01270	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AEQU_RS01280	COG0138	bifunctional purine biosynthesis protein purh
AEQU_RS01310	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AEQU_RS01320	COG2197	response regulator
AEQU_RS01325	COG2304	oxidoreductase activity
AEQU_RS01335	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQU_RS01340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEQU_RS01345	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AEQU_RS01350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEQU_RS01360	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AEQU_RS01365	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AEQU_RS01385	COG2357	RelA SpoT domain protein
AEQU_RS01395	COG0215	cysteine-tRNA ligase activity
AEQU_RS01400	COG1053	succinate dehydrogenase
AEQU_RS01400	COG3976	FMN-binding domain protein
AEQU_RS01410	COG0826	peptidase U32
AEQU_RS01425	COG0545	Peptidyl-prolyl cis-trans isomerase
AEQU_RS01430	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AEQU_RS01435	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AEQU_RS01440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AEQU_RS01445	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEQU_RS01450	COG0137	argininosuccinate synthase activity
AEQU_RS01460	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEQU_RS01470	COG0826	peptidase U32
AEQU_RS01475	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AEQU_RS01520	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AEQU_RS01530	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_RS01535	COG3383	formate dehydrogenase (NAD+) activity
AEQU_RS01540	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_RS01545	COG0651	ATP synthesis coupled electron transport
AEQU_RS01550	COG0650	Formate hydrogenlyase subunit 4
AEQU_RS01555	COG4237	Hydrogenase 4 membrane
AEQU_RS01560	COG0651	ATP synthesis coupled electron transport
AEQU_RS01565	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AEQU_RS01565	COG3261	NADH dehydrogenase
AEQU_RS01570	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEQU_RS01575	COG3260	NADH ubiquinone oxidoreductase 20
AEQU_RS01585	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AEQU_RS01590	COG2116	formate transmembrane transporter activity
AEQU_RS01595	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AEQU_RS01620	COG0586	Pfam SNARE associated Golgi protein
AEQU_RS01625	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AEQU_RS01630	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AEQU_RS01635	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AEQU_RS01650	COG1288	antiporter activity
AEQU_RS01695	COG0024	Methionine aminopeptidase
AEQU_RS01705	COG0697	spore germination
AEQU_RS01715	COG0477	Major facilitator Superfamily
AEQU_RS01730	COG0484	heat shock protein binding
AEQU_RS01760	COG1924	4 iron, 4 sulfur cluster binding
AEQU_RS01765	COG3381	protein complex oligomerization
AEQU_RS01775	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS01780	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS01785	COG0243	molybdopterin cofactor binding
AEQU_RS01795	COG2814	Major facilitator Superfamily
AEQU_RS01805	COG0243	molybdopterin cofactor binding
AEQU_RS01825	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_RS01855	COG3550	peptidyl-serine autophosphorylation
AEQU_RS01865	COG0326	Molecular chaperone. Has ATPase activity
AEQU_RS01885	COG3956	TIGRFAM MazG family protein
AEQU_RS01895	COG1053	succinate dehydrogenase
AEQU_RS01895	COG3976	FMN-binding domain protein
AEQU_RS01900	COG1228	amidohydrolase
AEQU_RS01905	COG2235	arginine
AEQU_RS01910	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_RS01915	COG0549	Belongs to the carbamate kinase family
AEQU_RS01920	COG1834	amidinotransferase
AEQU_RS01935	COG0477	Major facilitator Superfamily
AEQU_RS01945	COG1834	amidinotransferase
AEQU_RS01960	COG0436	Aminotransferase
AEQU_RS01990	COG2414	aldehyde ferredoxin oxidoreductase
AEQU_RS01995	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS02060	COG0482	sulfurtransferase activity
AEQU_RS02070	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AEQU_RS02075	COG2205	protein histidine kinase activity
AEQU_RS02075	COG0784	Response regulator, receiver
AEQU_RS02110	COG0542	response to heat
AEQU_RS02130	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEQU_RS02205	COG0560	Phosphoserine phosphatase
AEQU_RS02230	COG2843	Capsule synthesis protein
AEQU_RS02235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEQU_RS02245	COG0604	alcohol dehydrogenase
AEQU_RS02245	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_RS02245	COG3321	synthase
AEQU_RS02260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEQU_RS02265	COG0825	malonyl-CoA metabolic process
AEQU_RS02270	COG1748	Saccharopine dehydrogenase
AEQU_RS02295	COG1131	(ABC) transporter
AEQU_RS02335	COG1968	undecaprenyl-diphosphatase activity
AEQU_RS02345	COG1725	Transcriptional regulator
AEQU_RS02365	COG3550	peptidyl-serine autophosphorylation
AEQU_RS02385	COG0243	molybdopterin cofactor binding
AEQU_RS02390	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS02425	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AEQU_RS02445	COG3845	ABC transporter
AEQU_RS02450	COG1122	ATPase activity
AEQU_RS02455	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AEQU_RS02465	COG0657	acetylesterase activity
AEQU_RS02470	COG3973	AAA domain
AEQU_RS02495	COG0789	Transcriptional regulator
AEQU_RS02510	COG1201	RNA secondary structure unwinding
AEQU_RS02535	COG3254	rhamnose metabolic process
AEQU_RS02550	COG1288	antiporter activity
AEQU_RS02555	COG2235	arginine
AEQU_RS02560	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_RS02570	COG2848	UPF0210 protein
AEQU_RS02600	COG0542	response to heat
AEQU_RS02620	COG0288	reversible hydration of carbon dioxide
AEQU_RS02640	COG1725	Transcriptional regulator
AEQU_RS02645	COG0243	molybdopterin cofactor binding
AEQU_RS02650	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS02670	COG1316	TRANSCRIPTIONal
AEQU_RS02715	COG0822	iron-sulfur transferase activity
AEQU_RS02725	COG1959	2 iron, 2 sulfur cluster binding
AEQU_RS02735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_RS02735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_RS02740	COG0084	hydrolase, TatD family'
AEQU_RS02750	COG3550	peptidyl-serine autophosphorylation
AEQU_RS02760	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEQU_RS02770	COG1247	-acetyltransferase
AEQU_RS02775	COG0514	ATP-dependent DNA helicase (RecQ)
AEQU_RS02780	COG0538	isocitrate dehydrogenase activity
AEQU_RS02800	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AEQU_RS02805	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_RS02810	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS02815	COG0243	molybdopterin cofactor binding
AEQU_RS02830	COG0348	domain, Protein
AEQU_RS02845	COG1138	Cytochrome C-type biogenesis protein
AEQU_RS02850	COG4555	ABC transporter
AEQU_RS02890	COG3976	FMN-binding domain protein
AEQU_RS02890	COG1053	succinate dehydrogenase
AEQU_RS02910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AEQU_RS02930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AEQU_RS02950	COG2184	nucleotidyltransferase activity
AEQU_RS02955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEQU_RS02975	COG3853	Toxic anion resistance protein (TelA)
AEQU_RS02980	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AEQU_RS02995	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEQU_RS03005	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AEQU_RS03010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AEQU_RS03015	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AEQU_RS03020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AEQU_RS03025	COG0006	proline dipeptidase activity
AEQU_RS03035	COG3976	FMN-binding domain protein
AEQU_RS03035	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_RS03040	COG3381	protein complex oligomerization
AEQU_RS03045	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS03050	COG0243	molybdopterin cofactor binding
AEQU_RS03075	COG1053	succinate dehydrogenase
AEQU_RS03080	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AEQU_RS03090	COG0511	ligase activity, forming carbon-carbon bonds
AEQU_RS03090	COG5016	pyruvate
AEQU_RS03095	COG0439	Biotin carboxylase
AEQU_RS03105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEQU_RS03115	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEQU_RS03125	COG0004	ammonium transporteR
AEQU_RS03130	COG0347	Belongs to the P(II) protein family
AEQU_RS03155	COG0539	negative regulation of cytoplasmic translation
AEQU_RS03160	COG0237	dephospho-CoA kinase activity
AEQU_RS03170	COG1053	succinate dehydrogenase
AEQU_RS03190	COG0556	nucleotide-excision repair
AEQU_RS03200	COG0497	DNA recombination
AEQU_RS03220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AEQU_RS03225	COG0072	phenylalanine-tRNA ligase activity
AEQU_RS03230	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEQU_RS03235	COG0736	holo-[acyl-carrier-protein] synthase activity
AEQU_RS03240	COG2205	protein histidine kinase activity
AEQU_RS03240	COG2202	Pas domain
AEQU_RS03260	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AEQU_RS03280	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AEQU_RS03300	COG1134	teichoic acid transport
AEQU_RS03315	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AEQU_RS03330	COG1216	Glycosyl transferase, family 2
AEQU_RS03350	COG0706	membrane insertase activity
AEQU_RS03405	COG3328	transposase activity
AEQU_RS03440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEQU_RS03450	COG1215	transferase activity, transferring glycosyl groups
AEQU_RS03450	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AEQU_RS03465	COG1696	Membrane protein involved in D-alanine export
AEQU_RS03475	COG1088	dTDP-glucose 4,6-dehydratase activity
AEQU_RS03495	COG3475	LICD family
AEQU_RS03515	COG1216	Glycosyl transferase, family 2
AEQU_RS03525	COG1376	ErfK ybiS ycfS ynhG family protein
AEQU_RS03540	COG0697	spore germination
AEQU_RS03545	COG4750	Nucleotidyl transferase
AEQU_RS03550	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEQU_RS03550	COG1773	rubredoxin
AEQU_RS03555	COG1316	TRANSCRIPTIONal
AEQU_RS03565	COG0343	queuine tRNA-ribosyltransferase activity
AEQU_RS03570	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AEQU_RS03585	COG2197	response regulator
AEQU_RS03590	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEQU_RS03590	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEQU_RS03600	COG2197	response regulator
AEQU_RS03615	COG0535	radical SAM domain protein
AEQU_RS03625	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQU_RS03630	COG1120	ATPase activity
AEQU_RS03640	COG1122	ATPase activity
AEQU_RS03645	COG1122	ATPase activity
AEQU_RS03650	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AEQU_RS03660	COG1115	amino acid carrier protein
AEQU_RS03665	COG1115	amino acid carrier protein
AEQU_RS03670	COG2081	HI0933 family
AEQU_RS03675	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AEQU_RS03685	COG2267	carboxylic ester hydrolase activity
AEQU_RS03695	COG1401	restriction endodeoxyribonuclease activity
AEQU_RS03700	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AEQU_RS03710	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AEQU_RS03720	COG2131	deaminase
AEQU_RS03730	COG0356	it plays a direct role in the translocation of protons across the membrane
AEQU_RS03740	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEQU_RS03745	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEQU_RS03750	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AEQU_RS03755	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AEQU_RS03760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AEQU_RS03795	COG0101	tRNA pseudouridine synthase activity
AEQU_RS03800	COG4656	Part of a membrane complex involved in electron transport
AEQU_RS03805	COG0733	neurotransmitter:sodium symporter activity
AEQU_RS03810	COG0012	GTP binding
AEQU_RS03815	COG3177	Filamentation induced by cAMP protein fic
AEQU_RS03835	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEQU_RS03840	COG0154	amidase activity
AEQU_RS03845	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AEQU_RS03865	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEQU_RS03870	COG1144	Oxidoreductase
AEQU_RS03875	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEQU_RS03880	COG1013	pyruvate-flavodoxin oxidoreductase activity
AEQU_RS03885	COG0745	RESPONSE REGULATOR receiver
AEQU_RS03890	COG2205	protein histidine kinase activity
AEQU_RS03890	COG2202	Pas domain
AEQU_RS03895	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AEQU_RS03940	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AEQU_RS03955	COG2235	arginine
AEQU_RS03960	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_RS03965	COG1288	antiporter activity
AEQU_RS03970	COG0018	arginyl-trna synthetase
AEQU_RS03985	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEQU_RS03985	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEQU_RS04010	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AEQU_RS04030	COG0025	NhaP-type Na H and K H
AEQU_RS04035	COG0180	Tryptophanyl-tRNA synthetase
AEQU_RS04050	COG0494	nUDIX hydrolase
AEQU_RS04055	COG0488	(ABC) transporter
AEQU_RS04065	COG0025	NhaP-type Na H and K H
AEQU_RS04075	COG3976	FMN-binding domain protein
AEQU_RS04075	COG1053	succinate dehydrogenase
AEQU_RS04080	COG1994	Peptidase M50
AEQU_RS04090	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AEQU_RS04100	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AEQU_RS04105	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AEQU_RS04120	COG0784	Response regulator, receiver
AEQU_RS04120	COG2205	protein histidine kinase activity
AEQU_RS04140	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AEQU_RS04145	COG0204	Acyl-transferase
AEQU_RS04150	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AEQU_RS04160	COG1160	GTP binding
AEQU_RS04170	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AEQU_RS04185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AEQU_RS04190	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AEQU_RS04195	COG1104	cysteine desulfurase activity
AEQU_RS04215	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AEQU_RS04220	COG1302	Protein conserved in bacteria
AEQU_RS04225	COG1461	Dihydroxyacetone kinase
AEQU_RS04230	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEQU_RS04235	COG0742	ribosomal rna small subunit methyltransferase
AEQU_RS04250	COG0038	chloride channel
AEQU_RS04255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AEQU_RS04260	COG0416	fatty acid biosynthetic process
AEQU_RS04265	COG0571	ribonuclease III activity
AEQU_RS04270	COG1196	nuclear chromosome segregation
AEQU_RS04285	COG0243	molybdopterin cofactor binding
AEQU_RS04290	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS04300	COG2223	nitrite transmembrane transporter activity
AEQU_RS04320	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AEQU_RS04325	COG1215	transferase activity, transferring glycosyl groups
AEQU_RS04345	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AEQU_RS04375	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEQU_RS04385	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AEQU_RS04395	COG0513	Belongs to the DEAD box helicase family
AEQU_RS04400	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEQU_RS04420	COG1597	lipid kinase activity
AEQU_RS04430	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEQU_RS04435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEQU_RS04445	COG0105	UTP biosynthetic process
AEQU_RS04470	COG1077	Cell shape determining protein MreB Mrl
AEQU_RS04475	COG1792	Involved in formation and maintenance of cell shape
AEQU_RS04490	COG0772	Belongs to the SEDS family
AEQU_RS04510	COG0537	adenosine 5'-monophosphoramidase activity
AEQU_RS04535	COG1151	hydroxylamine reductase activity
AEQU_RS04555	COG0335	large ribosomal subunit rRNA binding
AEQU_RS04560	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AEQU_RS04565	COG0792	nuclease activity
AEQU_RS04575	COG0758	DNA mediated transformation
AEQU_RS04580	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AEQU_RS04595	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEQU_RS04605	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AEQU_RS04615	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEQU_RS04665	COG1074	ATP-dependent DNA helicase activity
AEQU_RS04675	COG1053	succinate dehydrogenase
AEQU_RS04680	COG0583	DNA-binding transcription factor activity
AEQU_RS04685	COG3976	FMN-binding domain protein
AEQU_RS04685	COG1053	succinate dehydrogenase
AEQU_RS04695	COG1053	succinate dehydrogenase
AEQU_RS04695	COG3976	FMN-binding domain protein
AEQU_RS04695	COG0431	NADPH-dependent FMN reductase
AEQU_RS04710	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AEQU_RS04720	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AEQU_RS04730	COG0318	PFAM AMP-dependent synthetase and ligase
AEQU_RS04750	COG1960	acyl-CoA dehydrogenase activity
AEQU_RS04760	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AEQU_RS04765	COG2086	electron transfer activity
AEQU_RS04770	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AEQU_RS04775	COG0247	lactate metabolic process
AEQU_RS04775	COG2181	nitrate reductase activity
AEQU_RS04795	COG0318	PFAM AMP-dependent synthetase and ligase
AEQU_RS04800	COG0318	PFAM AMP-dependent synthetase and ligase
AEQU_RS04815	COG1053	succinate dehydrogenase
AEQU_RS04815	COG3976	FMN-binding domain protein
AEQU_RS04830	COG0243	molybdopterin cofactor binding
AEQU_RS04835	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS04855	COG0243	molybdopterin cofactor binding
AEQU_RS04860	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS04870	COG1960	acyl-CoA dehydrogenase activity
AEQU_RS04880	COG0583	DNA-binding transcription factor activity
AEQU_RS04885	COG0779	Required for maturation of 30S ribosomal subunits
AEQU_RS04890	COG0195	Participates in both transcription termination and antitermination
AEQU_RS04900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AEQU_RS04900	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AEQU_RS04905	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AEQU_RS04910	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AEQU_RS04915	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AEQU_RS04920	COG0196	riboflavin kinase activity
AEQU_RS04925	COG1368	sulfuric ester hydrolase activity
AEQU_RS04930	COG0322	excinuclease ABC activity
AEQU_RS04935	COG1660	Displays ATPase and GTPase activities
AEQU_RS04940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AEQU_RS04945	COG1481	regulation of sporulation
AEQU_RS04955	COG0126	phosphoglycerate kinase activity
AEQU_RS04960	COG0149	triose-phosphate isomerase activity
AEQU_RS04965	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AEQU_RS04970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEQU_RS04990	COG0861	Integral membrane protein TerC family
AEQU_RS05060	COG1597	lipid kinase activity
AEQU_RS05065	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
AEQU_RS05070	COG2738	Putative neutral zinc metallopeptidase
AEQU_RS05075	COG1570	exodeoxyribonuclease VII activity
AEQU_RS05080	COG1722	exodeoxyribonuclease VII activity
AEQU_RS05085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AEQU_RS05090	COG3976	FMN-binding domain protein
AEQU_RS05090	COG1053	succinate dehydrogenase
AEQU_RS05100	COG0280	phosphate acetyltransferase
AEQU_RS05110	COG1215	transferase activity, transferring glycosyl groups
AEQU_RS05115	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEQU_RS05120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEQU_RS05130	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AEQU_RS05135	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AEQU_RS05140	COG0564	pseudouridine synthase activity
AEQU_RS05145	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AEQU_RS05155	COG1053	succinate dehydrogenase
AEQU_RS05160	COG0583	DNA-binding transcription factor activity
AEQU_RS05165	COG1053	succinate dehydrogenase
AEQU_RS05170	COG1053	succinate dehydrogenase
AEQU_RS05175	COG2197	response regulator
AEQU_RS05180	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQU_RS05185	COG1053	succinate dehydrogenase
AEQU_RS05185	COG3976	FMN-binding domain protein
AEQU_RS05210	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEQU_RS05210	COG2111	Na H antiporter
AEQU_RS05215	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AEQU_RS05220	COG3260	NADH ubiquinone oxidoreductase 20
AEQU_RS05235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AEQU_RS05245	COG2720	vancomycin resistance protein
AEQU_RS05260	COG1686	Belongs to the peptidase S11 family
AEQU_RS05285	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AEQU_RS05290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEQU_RS05350	COG0756	dUTP diphosphatase activity
AEQU_RS05355	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AEQU_RS05360	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEQU_RS05365	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AEQU_RS05375	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AEQU_RS05380	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQU_RS05385	COG2359	stage V sporulation protein S
AEQU_RS05395	COG1418	mRNA catabolic process
AEQU_RS05410	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AEQU_RS05415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQU_RS05420	COG1666	GTP binding
AEQU_RS05435	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AEQU_RS05440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEQU_RS05445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AEQU_RS05450	COG1185	polyribonucleotide nucleotidyltransferase activity
AEQU_RS05455	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AEQU_RS05475	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
AEQU_RS05490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQU_RS05495	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AEQU_RS05500	COG0484	heat shock protein binding
AEQU_RS05505	COG1420	regulation of RNA biosynthetic process
AEQU_RS05510	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQU_RS05530	COG0481	GTPase activity
AEQU_RS05535	COG0268	Binds directly to 16S ribosomal RNA
AEQU_RS05550	COG0658	competence protein
AEQU_RS05550	COG2333	competence protein COMEC
AEQU_RS05555	COG1555	photosystem II stabilization
AEQU_RS05555	COG1596	polysaccharide export
AEQU_RS05560	COG0301	tRNA thio-modification
AEQU_RS05570	COG0194	GDP metabolic process
AEQU_RS05580	COG0284	orotidine-5'-phosphate decarboxylase activity
AEQU_RS05585	COG0167	dihydroorotate dehydrogenase activity
AEQU_RS05590	COG0543	2 iron, 2 sulfur cluster binding
AEQU_RS05595	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AEQU_RS05600	COG0505	Belongs to the CarA family
AEQU_RS05605	COG1120	ATPase activity
AEQU_RS05610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQU_RS05615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQU_RS05620	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AEQU_RS05625	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEQU_RS05630	COG0540	Belongs to the ATCase OTCase family
AEQU_RS05635	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AEQU_RS05640	COG1592	Rubrerythrin
AEQU_RS05645	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AEQU_RS05650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEQU_RS05670	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEQU_RS05670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEQU_RS05675	COG1144	Oxidoreductase
AEQU_RS05685	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEQU_RS05700	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AEQU_RS05705	COG0242	peptide deformylase activity
AEQU_RS05710	COG0358	DNA primase activity
AEQU_RS05715	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AEQU_RS05720	COG0328	RNA-DNA hybrid ribonuclease activity
AEQU_RS05730	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQU_RS05735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AEQU_RS05740	COG0440	acetolactate synthase activity
AEQU_RS05745	COG0028	Belongs to the TPP enzyme family
AEQU_RS05750	COG0129	dihydroxy-acid dehydratase activity
AEQU_RS05765	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AEQU_RS05770	COG2890	protein-(glutamine-N5) methyltransferase activity
AEQU_RS05775	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AEQU_RS05790	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS05795	COG0243	molybdopterin cofactor binding
AEQU_RS05805	COG0475	glutathione-regulated potassium exporter activity
AEQU_RS05805	COG0569	domain protein
AEQU_RS05815	COG0492	ferredoxin-NADP+ reductase activity
AEQU_RS05820	COG4145	pantothenate transmembrane transporter activity
AEQU_RS05830	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AEQU_RS05845	COG0525	valine-tRNA ligase activity
AEQU_RS05850	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AEQU_RS05855	COG0740	serine-type endopeptidase activity
AEQU_RS05860	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEQU_RS05895	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
AEQU_RS05905	COG5263	repeat protein
AEQU_RS05905	COG5632	N-Acetylmuramoyl-L-alanine amidase
AEQU_RS06095	COG0592	DNA-directed DNA polymerase activity
AEQU_RS06145	COG1396	sequence-specific DNA binding
AEQU_RS06150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEQU_RS06175	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AEQU_RS06175	COG0116	Belongs to the methyltransferase superfamily
AEQU_RS06180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEQU_RS06185	COG0745	RESPONSE REGULATOR receiver
AEQU_RS06195	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS06200	COG0243	molybdopterin cofactor binding
AEQU_RS06215	COG1053	succinate dehydrogenase
AEQU_RS06220	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AEQU_RS06225	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AEQU_RS06250	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AEQU_RS06265	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEQU_RS06290	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AEQU_RS06325	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AEQU_RS06330	COG1605	Chorismate mutase
AEQU_RS06330	COG0077	Prephenate dehydratase
AEQU_RS06360	COG1132	(ABC) transporter
AEQU_RS06375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AEQU_RS06395	COG1192	Involved in chromosome partitioning
AEQU_RS06400	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AEQU_RS06405	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AEQU_RS06405	COG0574	Belongs to the PEP-utilizing enzyme family
AEQU_RS06415	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AEQU_RS06420	COG0751	glycine-tRNA ligase activity
AEQU_RS06425	COG0752	glycyl-tRNA synthetase alpha subunit
AEQU_RS06430	COG0681	Belongs to the peptidase S26 family
AEQU_RS06435	COG0336	Belongs to the RNA methyltransferase TrmD family
AEQU_RS06440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AEQU_RS06445	COG1837	Belongs to the UPF0109 family
AEQU_RS06465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AEQU_RS06470	COG0601	transmembrane transport
AEQU_RS06475	COG0747	negative chemotaxis
AEQU_RS06485	COG0552	protein localization to endoplasmic reticulum
AEQU_RS06490	COG0733	neurotransmitter:sodium symporter activity
AEQU_RS06500	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS06525	COG0557	exoribonuclease II activity
AEQU_RS06535	COG2177	Part of the ABC transporter FtsEX involved in
AEQU_RS06540	COG2884	Cell division ATP-binding protein ftsE
AEQU_RS06545	COG3958	Transketolase
AEQU_RS06580	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AEQU_RS06585	COG0653	protein targeting
AEQU_RS06595	COG1294	oxidase, subunit
AEQU_RS06600	COG1271	oxidase subunit
AEQU_RS06610	COG0799	negative regulation of ribosome biogenesis
AEQU_RS06615	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEQU_RS06615	COG1713	HD superfamily hydrolase involved in NAD metabolism
AEQU_RS06620	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEQU_RS06625	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AEQU_RS06630	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AEQU_RS06635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AEQU_RS06640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AEQU_RS06645	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AEQU_RS06650	COG1288	antiporter activity
AEQU_RS06655	COG2235	arginine
AEQU_RS06660	COG2197	response regulator
AEQU_RS06665	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEQU_RS06665	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEQU_RS06670	COG0745	RESPONSE REGULATOR receiver
AEQU_RS06675	COG0174	glutamine synthetase
AEQU_RS06685	COG2033	superoxide reductase activity
AEQU_RS06690	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AEQU_RS06705	COG0316	Belongs to the HesB IscA family
AEQU_RS06705	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AEQU_RS06715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AEQU_RS06735	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_RS06735	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQU_RS06750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AEQU_RS06755	COG0583	DNA-binding transcription factor activity
AEQU_RS06765	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AEQU_RS06795	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AEQU_RS06800	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AEQU_RS06805	COG0131	Imidazoleglycerol-phosphate dehydratase
AEQU_RS06810	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEQU_RS06815	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AEQU_RS06820	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AEQU_RS06825	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AEQU_RS06830	COG1691	(AIR) carboxylase
AEQU_RS06835	COG0789	Transcriptional regulator
AEQU_RS06845	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AEQU_RS06865	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AEQU_RS06870	COG1363	Peptidase, m42
AEQU_RS06900	COG1307	EDD domain protein, DegV family
AEQU_RS06915	COG1307	EDD domain protein, DegV family
AEQU_RS06920	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AEQU_RS06925	COG1774	PSP1 C-terminal conserved region
AEQU_RS06935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AEQU_RS06940	COG0281	malic enzyme
AEQU_RS06950	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AEQU_RS06950	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AEQU_RS06955	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AEQU_RS06955	COG0551	DNA topoisomerase type I activity
AEQU_RS06990	COG0765	amino acid transport
AEQU_RS06995	COG0765	amino acid transport
AEQU_RS07000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEQU_RS07010	COG3872	metal-dependent enzyme
AEQU_RS07015	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AEQU_RS07020	COG2226	methyltransferase
AEQU_RS07025	COG1278	Cold shock
AEQU_RS07035	COG2255	four-way junction helicase activity
AEQU_RS07040	COG0632	four-way junction helicase activity
AEQU_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_RS07055	COG0217	transcriptional regulatory protein
AEQU_RS07060	COG2909	trisaccharide binding
AEQU_RS07065	COG1053	succinate dehydrogenase
AEQU_RS07075	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AEQU_RS07085	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_RS07085	COG3976	FMN-binding domain protein
AEQU_RS07095	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS07100	COG0243	molybdopterin cofactor binding
AEQU_RS07110	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AEQU_RS07115	COG4149	molybdate abc transporter
AEQU_RS07145	COG0617	tRNA 3'-terminal CCA addition
AEQU_RS07180	COG1053	succinate dehydrogenase
AEQU_RS07180	COG3976	FMN-binding domain protein
AEQU_RS07185	COG0351	phosphomethylpyrimidine kinase
AEQU_RS07190	COG1335	isochorismatase
AEQU_RS07195	COG0352	thiamine-phosphate diphosphorylase activity
AEQU_RS07200	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AEQU_RS07215	COG0762	integral membrane protein
AEQU_RS07220	COG1799	cell septum assembly
AEQU_RS07230	COG1496	oxidoreductase activity
AEQU_RS07235	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AEQU_RS07240	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AEQU_RS07245	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AEQU_RS07250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEQU_RS07255	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEQU_RS07260	COG0772	Belongs to the SEDS family
AEQU_RS07265	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AEQU_RS07285	COG0768	penicillin binding
AEQU_RS07295	COG0275	rRNA processing
AEQU_RS07300	COG2001	Belongs to the MraZ family
AEQU_RS07305	COG4974	Belongs to the 'phage' integrase family
AEQU_RS07310	COG0252	asparaginase activity
AEQU_RS07315	COG2860	membrane
AEQU_RS07320	COG4868	Belongs to the UPF0371 family
AEQU_RS07340	COG0504	CTP synthase activity
AEQU_RS07345	COG0024	Methionine aminopeptidase
AEQU_RS07355	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AEQU_RS07360	COG0081	regulation of translation
AEQU_RS07365	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AEQU_RS07370	COG0250	Participates in transcription elongation, termination and antitermination
AEQU_RS07375	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEQU_RS07385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AEQU_RS07415	COG0426	domain, Protein
AEQU_RS07420	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEQU_RS07425	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_RS07435	COG1794	racemase activity, acting on amino acids and derivatives
AEQU_RS07445	COG3976	FMN-binding domain protein
AEQU_RS07445	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_RS07460	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQU_RS07460	COG1013	pyruvate-flavodoxin oxidoreductase activity
AEQU_RS07460	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AEQU_RS07460	COG0674	pyruvate-flavodoxin oxidoreductase activity
AEQU_RS07465	COG0747	negative chemotaxis
AEQU_RS07475	COG0563	adenylate kinase activity
AEQU_RS07485	COG0200	Binds to the 23S rRNA
AEQU_RS07490	COG1841	ribosomal large subunit assembly
AEQU_RS07495	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AEQU_RS07500	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AEQU_RS07505	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AEQU_RS07510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AEQU_RS07515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AEQU_RS07520	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEQU_RS07525	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AEQU_RS07530	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AEQU_RS07535	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AEQU_RS07545	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AEQU_RS07550	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AEQU_RS07560	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AEQU_RS07565	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AEQU_RS07590	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEQU_RS07600	COG1136	(ABC) transporter
AEQU_RS07625	COG2197	response regulator
AEQU_RS07640	COG0089	rRNA binding
AEQU_RS07645	COG0088	Forms part of the polypeptide exit tunnel
AEQU_RS07650	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AEQU_RS07655	COG0051	transcription antitermination factor activity, RNA binding
AEQU_RS07660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AEQU_RS07665	COG0049	tRNA binding
AEQU_RS07670	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AEQU_RS07685	COG1053	succinate dehydrogenase
AEQU_RS07700	COG2195	Cleaves the N-terminal amino acid of tripeptides
AEQU_RS07705	COG1227	inorganic diphosphatase activity
AEQU_RS07710	COG1760	l-serine dehydratase
AEQU_RS07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEQU_RS07755	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEQU_RS07770	COG2860	membrane
AEQU_RS07780	COG0306	phosphate transporter
AEQU_RS07785	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEQU_RS07790	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEQU_RS07795	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AEQU_RS07795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AEQU_RS07800	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AEQU_RS07805	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AEQU_RS07810	COG0602	queuosine metabolic process
AEQU_RS07815	COG0720	synthase
AEQU_RS07820	COG1739	Uncharacterized protein family UPF0029
AEQU_RS07825	COG0488	(ABC) transporter
AEQU_RS07830	COG2814	Major facilitator Superfamily
AEQU_RS07835	COG0193	aminoacyl-tRNA hydrolase activity
AEQU_RS07840	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEQU_RS07845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AEQU_RS07855	COG2217	Heavy metal translocating P-type atpase
AEQU_RS07860	COG1937	Protein conserved in bacteria
AEQU_RS07875	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEQU_RS07885	COG0598	Magnesium transport protein CorA
AEQU_RS07890	COG1573	uracil-dna glycosylase
AEQU_RS07895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEQU_RS07900	COG0521	Mo-molybdopterin cofactor biosynthetic process
AEQU_RS07905	COG0303	'Molybdopterin
AEQU_RS07910	COG1132	(ABC) transporter
AEQU_RS07920	COG3976	FMN-binding domain protein
AEQU_RS07920	COG1053	succinate dehydrogenase
AEQU_RS07935	COG4716	Myosin-crossreactive antigen
AEQU_RS07945	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
AEQU_RS07955	COG0203	ribosomal protein L17
AEQU_RS07960	COG0202	RNA polymerase activity
AEQU_RS07965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AEQU_RS07970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AEQU_RS07985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEQU_RS07990	COG2918	glutathione biosynthetic process
AEQU_RS07990	COG0189	ligase activity
AEQU_RS08020	COG2814	Major facilitator Superfamily
AEQU_RS08035	COG1966	Carbon starvation protein
AEQU_RS08060	COG0459	protein refolding
AEQU_RS08065	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AEQU_RS08070	COG2197	response regulator
AEQU_RS08075	COG4585	Histidine kinase
AEQU_RS08080	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AEQU_RS08080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEQU_RS08085	COG0375	protein maturation
AEQU_RS08090	COG0805	protein transport
AEQU_RS08095	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQU_RS08105	COG0402	S-adenosylhomocysteine deaminase activity
AEQU_RS08110	COG2226	methyltransferase
AEQU_RS08125	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
AEQU_RS08145	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS08150	COG0243	molybdopterin cofactor binding
AEQU_RS08160	COG0330	HflC and HflK could
AEQU_RS08175	COG0745	RESPONSE REGULATOR receiver
AEQU_RS08180	COG2205	protein histidine kinase activity
AEQU_RS08195	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AEQU_RS08210	COG0802	atpase or kinase
AEQU_RS08215	COG2116	formate transmembrane transporter activity
AEQU_RS08220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AEQU_RS08225	COG3404	Formiminotransferase-cyclodeaminase
AEQU_RS08230	COG2759	Belongs to the formate--tetrahydrofolate ligase family
AEQU_RS08235	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEQU_RS08240	COG0745	RESPONSE REGULATOR receiver
AEQU_RS08245	COG1268	BioY protein
AEQU_RS08255	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS08260	COG0243	molybdopterin cofactor binding
AEQU_RS08275	COG1053	succinate dehydrogenase
AEQU_RS08295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEQU_RS08300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEQU_RS08305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AEQU_RS08310	COG0424	maF-like protein
AEQU_RS08315	COG0037	tRNA processing
AEQU_RS08320	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEQU_RS08325	COG1950	PFAM Membrane protein of
AEQU_RS08330	COG0577	efflux transmembrane transporter activity
AEQU_RS08330	COG1136	(ABC) transporter
AEQU_RS08335	COG1528	Iron-storage protein
AEQU_RS08340	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEQU_RS08345	COG1272	protein, Hemolysin III
AEQU_RS08350	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AEQU_RS08360	COG0656	L-ascorbic acid biosynthetic process
AEQU_RS08365	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQU_RS08370	COG2078	PFAM AMMECR1 domain protein
AEQU_RS08370	COG3885	ferrous iron binding
AEQU_RS08375	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
AEQU_RS08380	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AEQU_RS08385	COG3250	beta-galactosidase activity
AEQU_RS08405	COG1053	succinate dehydrogenase
AEQU_RS08405	COG1053	succinate dehydrogenase
AEQU_RS08435	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS08440	COG0243	molybdopterin cofactor binding
AEQU_RS08450	COG0656	L-ascorbic acid biosynthetic process
AEQU_RS08460	COG1490	D-aminoacyl-tRNA deacylase activity
AEQU_RS08485	COG1053	succinate dehydrogenase
AEQU_RS08495	COG1373	ATPase (AAA superfamily
AEQU_RS08505	COG0613	PHP domain protein
AEQU_RS08510	COG4778	phosphonate C-P lyase system protein PhnL
AEQU_RS08515	COG3454	Phosphonate metabolism
AEQU_RS08520	COG4107	phosphonate C-P lyase system protein PhnK
AEQU_RS08525	COG3627	carbon phosphorus lyase activity
AEQU_RS08545	COG3639	organic phosphonate transmembrane transporter activity
AEQU_RS08550	COG3639	organic phosphonate transmembrane transporter activity
AEQU_RS08555	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AEQU_RS08570	COG1115	amino acid carrier protein
AEQU_RS08575	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AEQU_RS08585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEQU_RS08585	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEQU_RS08600	COG1132	(ABC) transporter
AEQU_RS08605	COG3973	AAA domain
AEQU_RS08610	COG0242	peptide deformylase activity
AEQU_RS08620	COG1234	tRNA 3'-trailer cleavage
AEQU_RS08690	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AEQU_RS08720	COG3550	peptidyl-serine autophosphorylation
AEQU_RS08730	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_RS08740	COG1053	succinate dehydrogenase
AEQU_RS08740	COG3976	FMN-binding domain protein
AEQU_RS08745	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEQU_RS08760	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AEQU_RS08770	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
AEQU_RS08780	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AEQU_RS08800	COG0549	Belongs to the carbamate kinase family
AEQU_RS08810	COG2153	protein acetylation
AEQU_RS08825	COG0659	secondary active sulfate transmembrane transporter activity
AEQU_RS08830	COG1053	succinate dehydrogenase
AEQU_RS08835	COG2909	trisaccharide binding
AEQU_RS08850	COG0569	domain protein
AEQU_RS08855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AEQU_RS08870	COG2832	Protein of unknown function (DUF454)
AEQU_RS08875	COG0363	glucosamine-6-phosphate deaminase activity
AEQU_RS08880	COG0659	secondary active sulfate transmembrane transporter activity
AEQU_RS08885	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_RS08890	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AEQU_RS08945	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEQU_RS08950	COG0732	type I restriction modification DNA specificity domain
AEQU_RS09005	COG3177	Filamentation induced by cAMP protein fic
AEQU_RS09025	COG0640	Transcriptional regulator
AEQU_RS09030	COG2217	Heavy metal translocating P-type atpase
AEQU_RS09035	COG2217	Heavy metal translocating P-type atpase
AEQU_RS09050	COG0222	ribosome binding
AEQU_RS09055	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AEQU_RS09060	COG2197	response regulator
AEQU_RS09065	COG1053	succinate dehydrogenase
AEQU_RS09080	COG1487	ribonuclease activity
AEQU_RS09090	COG0124	histidyl-tRNA synthetase
AEQU_RS09095	COG0473	3-isopropylmalate dehydrogenase activity
AEQU_RS09100	COG0066	3-isopropylmalate dehydratase activity
AEQU_RS09105	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AEQU_RS09115	COG0142	geranyltranstransferase activity
AEQU_RS09130	COG3976	FMN-binding domain protein
AEQU_RS09130	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_RS09140	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS09145	COG0243	molybdopterin cofactor binding
AEQU_RS09155	COG0745	RESPONSE REGULATOR receiver
AEQU_RS09160	COG5002	protein histidine kinase activity
AEQU_RS09195	COG1918	ferrous iron import across plasma membrane
AEQU_RS09195	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AEQU_RS09295	COG1131	(ABC) transporter
AEQU_RS09300	COG4585	Histidine kinase
AEQU_RS09305	COG2197	response regulator
AEQU_RS09310	COG1917	Cupin 2, conserved barrel domain protein
AEQU_RS09310	COG4977	sequence-specific DNA binding
AEQU_RS09315	COG0697	spore germination
AEQU_RS09335	COG3177	Filamentation induced by cAMP protein fic
AEQU_RS09355	COG2909	trisaccharide binding
AEQU_RS09360	COG2197	response regulator
AEQU_RS09375	COG3381	protein complex oligomerization
AEQU_RS09385	COG0348	domain, Protein
AEQU_RS09400	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS09430	COG0488	(ABC) transporter
AEQU_RS09440	COG1131	(ABC) transporter
AEQU_RS09465	COG1136	(ABC) transporter
AEQU_RS09470	COG5002	protein histidine kinase activity
AEQU_RS09475	COG0745	RESPONSE REGULATOR receiver
AEQU_RS09480	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AEQU_RS09490	COG1309	transcriptional regulator
AEQU_RS09510	COG2205	protein histidine kinase activity
AEQU_RS09510	COG0784	Response regulator, receiver
AEQU_RS09515	COG0495	leucyl-tRNA aminoacylation
AEQU_RS09525	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AEQU_RS09535	COG0583	DNA-binding transcription factor activity
AEQU_RS09555	COG1592	Rubrerythrin
AEQU_RS09560	COG1362	aminopeptidase activity
AEQU_RS09565	COG2957	Belongs to the agmatine deiminase family
AEQU_RS09570	COG0531	amino acid
AEQU_RS09575	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AEQU_RS09595	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AEQU_RS09600	COG2814	Major facilitator Superfamily
AEQU_RS09620	COG0745	RESPONSE REGULATOR receiver
AEQU_RS09625	COG3850	Histidine kinase
AEQU_RS09625	COG5002	protein histidine kinase activity
AEQU_RS09635	COG3976	FMN-binding domain protein
AEQU_RS09635	COG1053	succinate dehydrogenase
AEQU_RS09735	COG2205	protein histidine kinase activity
AEQU_RS09745	COG1131	(ABC) transporter
AEQU_RS09750	COG0745	RESPONSE REGULATOR receiver
AEQU_RS09780	COG0583	DNA-binding transcription factor activity
AEQU_RS09795	COG2814	Major facilitator Superfamily
AEQU_RS09800	COG0235	Class ii aldolase
AEQU_RS09805	COG1070	Carbohydrate kinase
AEQU_RS09805	COG4806	L-rhamnose isomerase
AEQU_RS09810	COG1070	Carbohydrate kinase
AEQU_RS09835	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AEQU_RS09840	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AEQU_RS09885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQU_RS09900	COG0067	glutamate synthase
AEQU_RS09905	COG0069	glutamate synthase activity
AEQU_RS09915	COG1053	succinate dehydrogenase
AEQU_RS09930	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
AEQU_RS09935	COG2873	o-acetylhomoserine
AEQU_RS09950	COG2909	trisaccharide binding
AEQU_RS09955	COG1053	succinate dehydrogenase
AEQU_RS10055	COG0460	homoserine dehydrogenase
AEQU_RS10065	COG0019	diaminopimelate decarboxylase activity
AEQU_RS10080	COG0733	neurotransmitter:sodium symporter activity
AEQU_RS10100	COG0398	Pfam SNARE associated Golgi protein
AEQU_RS10115	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEQU_RS10120	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_RS10135	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AEQU_RS10145	COG2815	serine threonine protein kinase
AEQU_RS10145	COG0515	serine threonine protein kinase
AEQU_RS10150	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AEQU_RS10160	COG3275	phosphorelay sensor kinase activity
AEQU_RS10165	COG0730	response to heat
AEQU_RS10175	COG1162	GTPase activity
AEQU_RS10190	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AEQU_RS10195	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AEQU_RS10200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEQU_RS10210	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AEQU_RS10215	COG5002	protein histidine kinase activity
AEQU_RS10220	COG0745	RESPONSE REGULATOR receiver
AEQU_RS10230	COG1472	Belongs to the glycosyl hydrolase 3 family
AEQU_RS10235	COG0785	Cytochrome C biogenesis protein
AEQU_RS10240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQU_RS10245	COG1053	succinate dehydrogenase
AEQU_RS10255	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AEQU_RS10295	COG2239	Acts as a magnesium transporter
AEQU_RS10305	COG1959	2 iron, 2 sulfur cluster binding
AEQU_RS10310	COG1757	Na H antiporter
AEQU_RS10330	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AEQU_RS10340	COG1169	isochorismate synthase
AEQU_RS10345	COG3830	Belongs to the UPF0237 family
AEQU_RS10350	COG0302	gtp cyclohydrolase
AEQU_RS10355	COG1970	mechanosensitive ion channel activity
AEQU_RS10370	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS10375	COG0243	molybdopterin cofactor binding
AEQU_RS10385	COG0708	Exodeoxyribonuclease III
AEQU_RS10390	COG1316	TRANSCRIPTIONal
AEQU_RS10405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEQU_RS10425	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS10430	COG0243	molybdopterin cofactor binding
AEQU_RS10435	COG0583	DNA-binding transcription factor activity
AEQU_RS10440	COG1053	succinate dehydrogenase
AEQU_RS10460	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
AEQU_RS10465	COG3189	MarR family transcriptional regulator
AEQU_RS10470	COG2233	PERMEase
AEQU_RS10475	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEQU_RS10485	COG2197	response regulator
AEQU_RS10500	COG3706	GGDEF domain
AEQU_RS10510	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQU_RS10520	COG0025	NhaP-type Na H and K H
AEQU_RS10525	COG0519	Catalyzes the synthesis of GMP from XMP
AEQU_RS10540	COG1073	alpha beta
AEQU_RS10545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEQU_RS10565	COG1396	sequence-specific DNA binding
AEQU_RS10575	COG0657	acetylesterase activity
AEQU_RS10585	COG2207	Transcriptional regulator
AEQU_RS10585	COG3708	Transcriptional regulator
AEQU_RS10590	COG0456	acetyltransferase
AEQU_RS10595	COG0477	Major facilitator Superfamily
AEQU_RS10615	COG2066	Belongs to the glutaminase family
AEQU_RS10620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AEQU_RS10630	COG1715	Restriction endonuclease
AEQU_RS10680	COG1393	Belongs to the ArsC family
AEQU_RS10690	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AEQU_RS10720	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AEQU_RS10740	COG0531	amino acid
AEQU_RS10755	COG2223	nitrite transmembrane transporter activity
AEQU_RS10765	COG1053	succinate dehydrogenase
AEQU_RS10765	COG3976	FMN-binding domain protein
AEQU_RS10770	COG2197	response regulator
AEQU_RS10775	COG0583	DNA-binding transcription factor activity
AEQU_RS10780	COG3976	FMN-binding domain protein
AEQU_RS10780	COG0431	NADPH-dependent FMN reductase
AEQU_RS10780	COG1053	succinate dehydrogenase
AEQU_RS10785	COG3976	FMN-binding domain protein
AEQU_RS10785	COG1053	succinate dehydrogenase
AEQU_RS10785	COG0431	NADPH-dependent FMN reductase
AEQU_RS10800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQU_RS10805	COG1120	ATPase activity
AEQU_RS10820	COG0745	RESPONSE REGULATOR receiver
AEQU_RS10825	COG5002	protein histidine kinase activity
AEQU_RS10840	COG1733	regulation of RNA biosynthetic process
AEQU_RS10850	COG3093	addiction module antidote protein HigA
AEQU_RS10870	COG0433	COG0433 Predicted ATPase
AEQU_RS10875	COG0390	transport system, permease component
AEQU_RS10880	COG3842	ATPase activity
AEQU_RS10945	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AEQU_RS10985	COG2205	protein histidine kinase activity
AEQU_RS10985	COG0784	Response regulator, receiver
AEQU_RS10995	COG3437	response regulator, receiver
AEQU_RS11005	COG0745	RESPONSE REGULATOR receiver
AEQU_RS11010	COG2205	protein histidine kinase activity
AEQU_RS11015	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS11095	COG1846	Transcriptional regulator
AEQU_RS11105	COG0765	amino acid transport
AEQU_RS11110	COG1126	abc transporter atp-binding protein
AEQU_RS11115	COG1842	Phage shock protein A
AEQU_RS11150	COG0631	protein serine/threonine phosphatase activity
AEQU_RS11160	COG0515	serine threonine protein kinase
AEQU_RS11160	COG2815	serine threonine protein kinase
AEQU_RS11175	COG5002	protein histidine kinase activity
AEQU_RS11180	COG0745	RESPONSE REGULATOR receiver
AEQU_RS11185	COG1283	sodium-dependent phosphate transmembrane transporter activity
AEQU_RS11190	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AEQU_RS11195	COG0581	inorganic phosphate transmembrane transporter activity
AEQU_RS11200	COG0573	inorganic phosphate transmembrane transporter activity
AEQU_RS11210	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AEQU_RS11210	COG3976	FMN-binding domain protein
AEQU_RS11220	COG0437	4 iron, 4 sulfur cluster binding
AEQU_RS11225	COG0243	molybdopterin cofactor binding
AEQU_RS11255	COG1328	CTP reductase activity
AEQU_RS11290	COG1511	domain protein
AEQU_RS11300	COG1160	GTP binding
AEQU_RS11310	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AEQU_RS11325	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AEQU_RS11330	COG0644	oxidoreductase
AEQU_RS11335	COG0446	pyridine nucleotide-disulphide oxidoreductase
AEQU_RS11335	COG1902	pentaerythritol trinitrate reductase activity
AEQU_RS11345	COG1028	Short-chain dehydrogenase reductase Sdr
AEQU_RS11350	COG1053	succinate dehydrogenase
AEQU_RS11350	COG0431	NADPH-dependent FMN reductase
AEQU_RS11350	COG3976	FMN-binding domain protein
AEQU_RS11390	COG3177	Filamentation induced by cAMP protein fic
AEQU_RS11405	COG1053	succinate dehydrogenase
AEQU_RS11430	COG1979	alcohol dehydrogenase
AEQU_RS11445	COG0726	polysaccharide deacetylase
AEQU_RS11450	COG1045	serine acetyltransferase
AEQU_RS11455	COG2814	Major facilitator Superfamily
AEQU_RS11460	COG1253	flavin adenine dinucleotide binding
AEQU_RS11480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEQU_RS11485	COG1217	gtp-binding protein TYPA
AEQU_RS11515	COG3328	transposase activity
AEQU_RS11610	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AEQU_RS11615	COG0187	DNA topoisomerase II activity
AEQU_RS11620	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AEQU_RS11660	COG4509	Sortase family
AEQU_RS11670	COG1876	peptidase activity
AEQU_RS11675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AEQU_RS11700	COG0515	serine threonine protein kinase
AEQU_RS11700	COG2815	serine threonine protein kinase
AEQU_RS11715	COG0824	Thioesterase
AEQU_RS11720	COG1396	sequence-specific DNA binding
AEQU_RS11730	COG0784	Response regulator, receiver
AEQU_RS11730	COG2205	protein histidine kinase activity
AEQU_RS11765	COG2197	response regulator
AEQU_RS11775	COG3942	CHAP domain
AEQU_RS11775	COG1705	Flagellar rod assembly protein muramidase FlgJ
AEQU_RS11780	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
AEQU_RS11785	COG1216	Glycosyl transferase, family 2
AEQU_RS11790	COG1216	Glycosyl transferase, family 2
AEQU_RS11805	COG0653	protein targeting
AEQU_RS11840	COG2226	methyltransferase
AEQU_RS11870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AEQU_RS11870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEQU_RS11880	COG0740	serine-type endopeptidase activity
AEQU_RS11925	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AEQU_RS11935	COG0784	Response regulator, receiver
AEQU_RS11935	COG2205	protein histidine kinase activity
AEQU_RS11980	COG0583	DNA-binding transcription factor activity
AEQU_RS11990	COG1396	sequence-specific DNA binding
AEQU_RS12015	COG3177	Filamentation induced by cAMP protein fic
AEQU_RS12055	COG0243	molybdopterin cofactor binding
AEQU_RS12060	COG0583	DNA-binding transcription factor activity
AEQU_RS12065	COG1122	ATPase activity