locus-tag	class	description
TKWG_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
TKWG_RS00020	COG0697	spore germination
TKWG_RS00025	COG1309	transcriptional regulator
TKWG_RS00040	COG0583	DNA-binding transcription factor activity
TKWG_RS00070	COG1733	regulation of RNA biosynthetic process
TKWG_RS00100	COG0583	DNA-binding transcription factor activity
TKWG_RS00105	COG1335	isochorismatase
TKWG_RS00120	COG0625	glutathione transferase activity
TKWG_RS00135	COG0625	glutathione transferase activity
TKWG_RS00140	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TKWG_RS00150	COG1802	Transcriptional regulator
TKWG_RS00160	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS00165	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS00170	COG1063	alcohol dehydrogenase
TKWG_RS00175	COG3962	Belongs to the TPP enzyme family
TKWG_RS00190	COG1522	sequence-specific DNA binding
TKWG_RS00205	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS00215	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS00225	COG1802	Transcriptional regulator
TKWG_RS00235	COG4948	Mandelate Racemase Muconate Lactonizing
TKWG_RS00245	COG0179	Fumarylacetoacetate (FAA) hydrolase
TKWG_RS00250	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TKWG_RS00255	COG4948	Mandelate Racemase Muconate Lactonizing
TKWG_RS00270	COG0251	oxidation-reduction process
TKWG_RS00290	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TKWG_RS00295	COG0798	PFAM Bile acid sodium symporter
TKWG_RS00305	COG2205	protein histidine kinase activity
TKWG_RS00330	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
TKWG_RS00335	COG2181	nitrate reductase activity
TKWG_RS00350	COG1250	3-hydroxyacyl-CoA dehydrogenase
TKWG_RS00355	COG3257	ureidoglycine aminohydrolase activity
TKWG_RS00365	COG1301	dicarboxylic acid transport
TKWG_RS00380	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
TKWG_RS00400	COG1414	Transcriptional regulator
TKWG_RS00405	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
TKWG_RS00410	COG3485	protocatechuate 3,4-dioxygenase
TKWG_RS00420	COG0583	DNA-binding transcription factor activity
TKWG_RS00440	COG0673	inositol 2-dehydrogenase activity
TKWG_RS00465	COG0590	tRNA wobble adenosine to inosine editing
TKWG_RS00470	COG2807	transmembrane transport
TKWG_RS00480	COG0583	DNA-binding transcription factor activity
TKWG_RS00490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TKWG_RS00500	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
TKWG_RS00520	COG1335	isochorismatase
TKWG_RS00525	COG5517	Aromatic-ring-hydroxylating dioxygenase beta subunit
TKWG_RS00535	COG0446	pyridine nucleotide-disulphide oxidoreductase
TKWG_RS00540	COG2146	nitrite reductase [NAD(P)H] activity
TKWG_RS00545	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TKWG_RS00590	COG3473	Maleate cis-trans isomerase
TKWG_RS00600	COG1487	ribonuclease activity
TKWG_RS00610	COG3755	Protein conserved in bacteria
TKWG_RS00625	COG3237	CsbD-like
TKWG_RS00635	COG1546	Belongs to the CinA family
TKWG_RS00650	COG1573	uracil-dna glycosylase
TKWG_RS00655	COG1280	lysine exporter protein (LysE YggA)
TKWG_RS00660	COG1609	Transcriptional regulator
TKWG_RS00665	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TKWG_RS00690	COG0861	Integral membrane protein TerC family
TKWG_RS00710	COG2706	6-phosphogluconolactonase activity
TKWG_RS00750	COG4771	TonB-dependent receptor
TKWG_RS00775	COG2211	Major facilitator Superfamily
TKWG_RS00835	COG2010	Cytochrome c
TKWG_RS00835	COG1529	Aldehyde oxidase and xanthine dehydrogenase
TKWG_RS00855	COG0559	Belongs to the binding-protein-dependent transport system permease family
TKWG_RS00880	COG0596	Alpha beta hydrolase
TKWG_RS00885	COG2309	aminopeptidase activity
TKWG_RS00890	COG1335	isochorismatase
TKWG_RS00895	COG1309	transcriptional regulator
TKWG_RS00930	COG2188	Transcriptional regulator
TKWG_RS00940	COG1230	cation diffusion facilitator family transporter
TKWG_RS00960	COG0583	DNA-binding transcription factor activity
TKWG_RS00995	COG5383	Protein conserved in bacteria
TKWG_RS01005	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TKWG_RS01010	COG4605	iron ion homeostasis
TKWG_RS01015	COG4604	ABC transporter, ATP-binding protein
TKWG_RS01040	COG3284	Transcriptional regulator
TKWG_RS01045	COG1012	belongs to the aldehyde dehydrogenase family
TKWG_RS01080	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TKWG_RS01105	COG2162	N-hydroxyarylamine O-acetyltransferase activity
TKWG_RS01135	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
TKWG_RS01150	COG3189	MarR family transcriptional regulator
TKWG_RS01165	COG1335	isochorismatase
TKWG_RS01175	COG1414	Transcriptional regulator
TKWG_RS01185	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS01200	COG1560	Kdo2-lipid A biosynthetic process
TKWG_RS01235	COG0583	DNA-binding transcription factor activity
TKWG_RS01260	COG0842	Transport permease protein
TKWG_RS01280	COG4176	ABC-type proline glycine betaine transport system permease component
TKWG_RS01300	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS01305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS01325	COG2129	metallophosphoesterase
TKWG_RS01345	COG1247	-acetyltransferase
TKWG_RS01355	COG0444	Belongs to the ABC transporter superfamily
TKWG_RS01360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TKWG_RS01365	COG0601	transmembrane transport
TKWG_RS01370	COG4608	Belongs to the ABC transporter superfamily
TKWG_RS01405	COG2161	toxin-antitoxin pair type II binding
TKWG_RS01505	COG1414	Transcriptional regulator
TKWG_RS01510	COG1024	Enoyl-CoA hydratase
TKWG_RS01525	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS01530	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS01545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TKWG_RS01560	COG5339	Protein conserved in bacteria
TKWG_RS01575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
TKWG_RS01580	COG0028	Belongs to the TPP enzyme family
TKWG_RS01590	COG0601	transmembrane transport
TKWG_RS01595	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TKWG_RS01600	COG0444	Belongs to the ABC transporter superfamily
TKWG_RS01605	COG4608	Belongs to the ABC transporter superfamily
TKWG_RS01620	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS01665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TKWG_RS01690	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
TKWG_RS01700	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
TKWG_RS01725	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TKWG_RS01730	COG0183	Belongs to the thiolase family
TKWG_RS01755	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TKWG_RS01775	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS01800	COG1024	Enoyl-CoA hydratase
TKWG_RS01805	COG2188	Transcriptional regulator
TKWG_RS01830	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
TKWG_RS01855	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TKWG_RS01875	COG2193	ferroxidase activity
TKWG_RS01900	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
TKWG_RS01935	COG1160	GTP binding
TKWG_RS01955	COG0697	spore germination
TKWG_RS01985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TKWG_RS01990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
TKWG_RS01990	COG0678	peroxiredoxin activity
TKWG_RS02015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS02045	COG3045	CreA protein
TKWG_RS02055	COG0405	Gamma-glutamyltransferase
TKWG_RS02080	COG0778	Nitroreductase
TKWG_RS02090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TKWG_RS02095	COG1116	anion transmembrane transporter activity
TKWG_RS02105	COG2175	clavaminate synthase activity
TKWG_RS02110	COG1741	Belongs to the pirin family
TKWG_RS02150	COG2271	Major facilitator Superfamily
TKWG_RS02155	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS02165	COG1414	Transcriptional regulator
TKWG_RS02195	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS02220	COG2009	succinate dehydrogenase
TKWG_RS02235	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
TKWG_RS02260	COG3038	cytochrome b561
TKWG_RS02305	COG2070	2-Nitropropane dioxygenase
TKWG_RS02310	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS02335	COG1335	isochorismatase
TKWG_RS02350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS02355	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS02360	COG0604	alcohol dehydrogenase
TKWG_RS02370	COG1522	sequence-specific DNA binding
TKWG_RS02380	COG0463	Glycosyl transferase, family 2
TKWG_RS02385	COG2814	Major facilitator Superfamily
TKWG_RS02390	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
TKWG_RS02400	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
TKWG_RS02445	COG0109	protoheme IX farnesyltransferase activity
TKWG_RS02450	COG1999	signal sequence binding
TKWG_RS02460	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
TKWG_RS02480	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
TKWG_RS02485	COG0513	Belongs to the DEAD box helicase family
TKWG_RS02500	COG1127	ABC transporter
TKWG_RS02505	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
TKWG_RS02510	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TKWG_RS02530	COG1131	(ABC) transporter
TKWG_RS02535	COG0842	Transport permease protein
TKWG_RS02540	COG0271	Belongs to the BolA IbaG family
TKWG_RS02545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
TKWG_RS02550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
TKWG_RS02560	COG0131	Imidazoleglycerol-phosphate dehydratase
TKWG_RS02570	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
TKWG_RS02580	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
TKWG_RS02585	COG0140	phosphoribosyl-ATP diphosphatase activity
TKWG_RS02590	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
TKWG_RS02600	COG0805	protein transport
TKWG_RS02605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TKWG_RS02615	COG1970	mechanosensitive ion channel activity
TKWG_RS02630	COG2857	Cytochrome c1
TKWG_RS02635	COG0625	glutathione transferase activity
TKWG_RS02640	COG2969	positive regulation of protein catabolic process
TKWG_RS02650	COG2096	Adenosyltransferase
TKWG_RS02660	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
TKWG_RS02665	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
TKWG_RS02675	COG0523	cobalamin synthesis protein
TKWG_RS02680	COG0735	belongs to the Fur family
TKWG_RS02690	COG1121	(ABC) transporter
TKWG_RS02700	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
TKWG_RS02715	COG1560	Kdo2-lipid A biosynthetic process
TKWG_RS02720	COG2076	Multidrug Resistance protein
TKWG_RS02740	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
TKWG_RS02745	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
TKWG_RS02750	COG1950	PFAM Membrane protein of
TKWG_RS02755	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
TKWG_RS02760	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
TKWG_RS02770	COG0617	tRNA 3'-terminal CCA addition
TKWG_RS02805	COG0513	Belongs to the DEAD box helicase family
TKWG_RS02820	COG0134	indole-3-glycerol-phosphate synthase activity
TKWG_RS02830	COG0512	Glutamine amidotransferase of anthranilate synthase
TKWG_RS02840	COG0546	phosphoglycolate phosphatase activity
TKWG_RS02850	COG2967	ApaG domain
TKWG_RS02875	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
TKWG_RS02885	COG2823	Periplasmic or secreted lipoprotein
TKWG_RS02890	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
TKWG_RS02910	COG1660	Displays ATPase and GTPase activities
TKWG_RS02915	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
TKWG_RS02925	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
TKWG_RS02930	COG1137	ATPase activity
TKWG_RS02945	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
TKWG_RS02965	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
TKWG_RS02970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
TKWG_RS02975	COG1238	metal cluster binding
TKWG_RS02985	COG1984	allophanate hydrolase subunit 2
TKWG_RS02990	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
TKWG_RS03010	COG5002	protein histidine kinase activity
TKWG_RS03020	COG2226	methyltransferase
TKWG_RS03075	COG0351	phosphomethylpyrimidine kinase
TKWG_RS03080	COG2326	polyphosphate kinase activity
TKWG_RS03095	COG0791	NLP P60 protein
TKWG_RS03110	COG1446	asparaginase
TKWG_RS03120	COG0747	negative chemotaxis
TKWG_RS03125	COG0601	transmembrane transport
TKWG_RS03130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TKWG_RS03150	COG1794	racemase activity, acting on amino acids and derivatives
TKWG_RS03165	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS03200	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
TKWG_RS03205	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
TKWG_RS03215	COG2188	Transcriptional regulator
TKWG_RS03220	COG3624	Phosphonate C-P lyase system protein PhnG
TKWG_RS03230	COG3626	phosphonate metabolism
TKWG_RS03235	COG3627	carbon phosphorus lyase activity
TKWG_RS03250	COG3454	Phosphonate metabolism
TKWG_RS03305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS03310	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
TKWG_RS03335	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TKWG_RS03345	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TKWG_RS03350	COG0473	3-isopropylmalate dehydrogenase activity
TKWG_RS03355	COG0252	asparaginase activity
TKWG_RS03360	COG0667	Aldo Keto reductase
TKWG_RS03365	COG3284	Transcriptional regulator
TKWG_RS03375	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
TKWG_RS03380	COG4647	ligase activity
TKWG_RS03385	COG2610	gluconate transmembrane transporter activity
TKWG_RS03400	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
TKWG_RS03475	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS03510	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS03530	COG2321	neutral zinc metallopeptidase
TKWG_RS03535	COG1994	Peptidase M50
TKWG_RS03540	COG3568	Endonuclease Exonuclease Phosphatase
TKWG_RS03560	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
TKWG_RS03565	COG2945	thiolester hydrolase activity
TKWG_RS03570	COG1686	Belongs to the peptidase S11 family
TKWG_RS03580	COG2921	Belongs to the UPF0250 family
TKWG_RS03590	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
TKWG_RS03595	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
TKWG_RS03600	COG0438	transferase activity, transferring glycosyl groups
TKWG_RS03615	COG0438	transferase activity, transferring glycosyl groups
TKWG_RS03670	COG1946	Acyl-CoA thioesterase
TKWG_RS03685	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
TKWG_RS03730	COG0095	Lipoate-protein ligase
TKWG_RS03740	COG0242	peptide deformylase activity
TKWG_RS03745	COG0758	DNA mediated transformation
TKWG_RS03750	COG0431	NADPH-dependent FMN reductase
TKWG_RS03775	COG0546	phosphoglycolate phosphatase activity
TKWG_RS03780	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TKWG_RS03785	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TKWG_RS03785	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TKWG_RS03800	COG2204	response regulator
TKWG_RS03805	COG0569	domain protein
TKWG_RS03815	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
TKWG_RS03820	COG0010	Belongs to the arginase family
TKWG_RS03830	COG0765	amino acid transport
TKWG_RS03835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS03840	COG1414	Transcriptional regulator
TKWG_RS03845	COG1040	competence protein
TKWG_RS03850	COG2226	methyltransferase
TKWG_RS03860	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
TKWG_RS03865	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
TKWG_RS03875	COG0588	phosphoglycerate mutase activity
TKWG_RS03880	COG4942	peptidase
TKWG_RS03890	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
TKWG_RS03900	COG1024	Enoyl-CoA hydratase
TKWG_RS03910	COG0356	it plays a direct role in the translocation of protons across the membrane
TKWG_RS03925	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
TKWG_RS03935	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
TKWG_RS03945	COG0355	proton-transporting ATP synthase activity, rotational mechanism
TKWG_RS03960	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS03980	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
TKWG_RS03995	COG3245	cytochrome
TKWG_RS04025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TKWG_RS04040	COG0583	DNA-binding transcription factor activity
TKWG_RS04055	COG4977	sequence-specific DNA binding
TKWG_RS04055	COG1917	Cupin 2, conserved barrel domain protein
TKWG_RS04130	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS04145	COG0601	transmembrane transport
TKWG_RS04170	COG0154	amidase activity
TKWG_RS04180	COG0477	Major facilitator Superfamily
TKWG_RS04210	COG2186	Transcriptional regulator
TKWG_RS04215	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS04220	COG4948	Mandelate Racemase Muconate Lactonizing
TKWG_RS04240	COG1609	Transcriptional regulator
TKWG_RS04245	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS04260	COG1850	ribulose-bisphosphate carboxylase activity
TKWG_RS04270	COG3360	Dodecin
TKWG_RS04290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS04315	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TKWG_RS04320	COG0765	amino acid transport
TKWG_RS04325	COG0765	amino acid transport
TKWG_RS04330	COG1126	abc transporter atp-binding protein
TKWG_RS04400	COG0436	Aminotransferase
TKWG_RS04405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS04420	COG1126	abc transporter atp-binding protein
TKWG_RS04435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS04450	COG1024	Enoyl-CoA hydratase
TKWG_RS04465	COG1024	Enoyl-CoA hydratase
TKWG_RS04470	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS04480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TKWG_RS04505	COG1177	transmembrane transport
TKWG_RS04510	COG1176	ABC-type spermidine putrescine transport system, permease component I
TKWG_RS04515	COG3842	ATPase activity
TKWG_RS04540	COG0583	DNA-binding transcription factor activity
TKWG_RS04570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS04575	COG4215	(ABC) transporter
TKWG_RS04580	COG4160	amino acid transport
TKWG_RS04585	COG4598	ABC transporter
TKWG_RS04615	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TKWG_RS04615	COG2813	Specifically methylates the guanine in position
TKWG_RS04620	COG2223	nitrite transmembrane transporter activity
TKWG_RS04630	COG2010	Cytochrome c
TKWG_RS04655	COG0583	DNA-binding transcription factor activity
TKWG_RS04660	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
TKWG_RS04665	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TKWG_RS04675	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
TKWG_RS04685	COG1792	Involved in formation and maintenance of cell shape
TKWG_RS04695	COG0768	penicillin binding
TKWG_RS04705	COG1194	a g-specific adenine glycosylase
TKWG_RS04710	COG2177	Part of the ABC transporter FtsEX involved in
TKWG_RS04715	COG2884	Cell division ATP-binding protein ftsE
TKWG_RS04725	COG4597	amino acid ABC transporter
TKWG_RS04735	COG1126	abc transporter atp-binding protein
TKWG_RS04745	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
TKWG_RS04750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
TKWG_RS04755	COG2197	response regulator
TKWG_RS04775	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
TKWG_RS04780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
TKWG_RS04800	COG1045	serine acetyltransferase
TKWG_RS04815	COG0142	geranyltranstransferase activity
TKWG_RS04820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS04825	COG0765	amino acid transport
TKWG_RS04835	COG0129	dihydroxy-acid dehydratase activity
TKWG_RS04850	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TKWG_RS04855	COG3707	response regulator
TKWG_RS04860	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TKWG_RS04905	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
TKWG_RS04920	COG1309	transcriptional regulator
TKWG_RS04930	COG2814	Major facilitator Superfamily
TKWG_RS04935	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
TKWG_RS04940	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
TKWG_RS04945	COG0211	Belongs to the bacterial ribosomal protein bL27 family
TKWG_RS04950	COG0261	This protein binds to 23S rRNA in the presence of protein L20
TKWG_RS04970	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
TKWG_RS04975	COG0352	thiamine-phosphate diphosphorylase activity
TKWG_RS04980	COG0351	phosphomethylpyrimidine kinase
TKWG_RS04985	COG1773	rubredoxin
TKWG_RS04990	COG1678	Uncharacterized ACR, COG1678
TKWG_RS05000	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
TKWG_RS05020	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TKWG_RS05035	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
TKWG_RS05045	COG3150	esterase
TKWG_RS05055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TKWG_RS05060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
TKWG_RS05110	COG0045	succinate-CoA ligase (ADP-forming) activity
TKWG_RS05110	COG1042	CoA-binding domain protein
TKWG_RS05110	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TKWG_RS05120	COG3028	Belongs to the UPF0307 family
TKWG_RS05130	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TKWG_RS05135	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
TKWG_RS05140	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
TKWG_RS05155	COG0316	Belongs to the HesB IscA family
TKWG_RS05160	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
TKWG_RS05165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
TKWG_RS05180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
TKWG_RS05185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TKWG_RS05185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
TKWG_RS05205	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
TKWG_RS05230	COG2837	iron assimilation
TKWG_RS05255	COG1999	signal sequence binding
TKWG_RS05265	COG1473	amidohydrolase
TKWG_RS05295	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
TKWG_RS05300	COG0252	asparaginase activity
TKWG_RS05320	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
TKWG_RS05320	COG0475	glutathione-regulated potassium exporter activity
TKWG_RS05360	COG1280	lysine exporter protein (LysE YggA)
TKWG_RS05370	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS05380	COG0583	DNA-binding transcription factor activity
TKWG_RS05435	COG5507	3-demethylubiquinone-9 3-methyltransferase
TKWG_RS05455	COG0328	RNA-DNA hybrid ribonuclease activity
TKWG_RS05460	COG2226	methyltransferase
TKWG_RS05465	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
TKWG_RS05470	COG0741	lytic transglycosylase activity
TKWG_RS05470	COG1388	LysM domain
TKWG_RS05480	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
TKWG_RS05485	COG0463	Glycosyl transferase, family 2
TKWG_RS05505	COG0589	response to stress
TKWG_RS05510	COG0642	Histidine kinase
TKWG_RS05520	COG2223	nitrite transmembrane transporter activity
TKWG_RS05530	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
TKWG_RS05545	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
TKWG_RS05560	COG0746	molybdenum cofactor guanylyltransferase activity
TKWG_RS05570	COG0521	Mo-molybdopterin cofactor biosynthetic process
TKWG_RS05575	COG0314	molybdopterin synthase activity
TKWG_RS05585	COG0315	cyclic pyranopterin monophosphate synthase activity
TKWG_RS05590	COG0678	peroxiredoxin activity
TKWG_RS05595	COG0477	Major facilitator Superfamily
TKWG_RS05615	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
TKWG_RS05620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS05640	COG0494	nUDIX hydrolase
TKWG_RS05645	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TKWG_RS05660	COG2721	sulfolactate sulfo-lyase activity
TKWG_RS05665	COG2186	Transcriptional regulator
TKWG_RS05670	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
TKWG_RS05690	COG3443	Belongs to the bacterial solute-binding protein 9 family
TKWG_RS05735	COG0587	DNA-directed DNA polymerase activity
TKWG_RS05745	COG0815	Transfers the fatty acyl group on membrane lipoproteins
TKWG_RS05755	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
TKWG_RS05760	COG1702	phosphate starvation-inducible protein PhoH
TKWG_RS05765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
TKWG_RS05775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
TKWG_RS05785	COG1862	Preprotein translocase
TKWG_RS05790	COG0343	queuine tRNA-ribosyltransferase activity
TKWG_RS05795	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
TKWG_RS05810	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
TKWG_RS05830	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
TKWG_RS05840	COG0436	Aminotransferase
TKWG_RS05865	COG1385	rRNA (uridine-N3-)-methyltransferase activity
TKWG_RS05875	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
TKWG_RS05880	COG0126	phosphoglycerate kinase activity
TKWG_RS05900	COG0521	Mo-molybdopterin cofactor biosynthetic process
TKWG_RS05925	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
TKWG_RS05930	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
TKWG_RS05935	COG0009	L-threonylcarbamoyladenylate synthase
TKWG_RS05940	COG1473	amidohydrolase
TKWG_RS05965	COG0415	Belongs to the DNA photolyase family
TKWG_RS05970	COG1309	transcriptional regulator
TKWG_RS05985	COG1021	2,3-dihydroxybenzoate-AMP ligase
TKWG_RS06000	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS06015	COG2267	carboxylic ester hydrolase activity
TKWG_RS06025	COG1396	sequence-specific DNA binding
TKWG_RS06030	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS06035	COG0765	amino acid transport
TKWG_RS06040	COG1126	abc transporter atp-binding protein
TKWG_RS06045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TKWG_RS06050	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TKWG_RS06060	COG1490	D-aminoacyl-tRNA deacylase activity
TKWG_RS06070	COG1346	cytolysis
TKWG_RS06085	COG3836	Belongs to the HpcH HpaI aldolase family
TKWG_RS06115	COG0412	Dienelactone hydrolase
TKWG_RS06120	COG2989	Protein conserved in bacteria
TKWG_RS06125	COG3108	Peptidase M15
TKWG_RS06130	COG1250	3-hydroxyacyl-CoA dehydrogenase
TKWG_RS06140	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
TKWG_RS06145	COG3246	L-lysine catabolic process to acetate
TKWG_RS06190	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TKWG_RS06210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS06215	COG0765	amino acid transport
TKWG_RS06220	COG0765	amino acid transport
TKWG_RS06230	COG1802	Transcriptional regulator
TKWG_RS06240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
TKWG_RS06250	COG0825	malonyl-CoA metabolic process
TKWG_RS06260	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
TKWG_RS06330	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
TKWG_RS06395	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS06405	COG2030	dehydratase
TKWG_RS06410	COG0831	urea catabolic process
TKWG_RS06415	COG0832	Belongs to the urease beta subunit family
TKWG_RS06430	COG0829	nickel cation binding
TKWG_RS06435	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TKWG_RS06465	COG3121	Chaperone
TKWG_RS06470	COG3539	Fimbrial protein
TKWG_RS06485	COG0579	oxidoreductase
TKWG_RS06490	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TKWG_RS06505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
TKWG_RS06530	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
TKWG_RS06540	COG1215	transferase activity, transferring glycosyl groups
TKWG_RS06565	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
TKWG_RS06570	COG2894	cell division
TKWG_RS06610	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
TKWG_RS06630	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
TKWG_RS06645	COG0346	lactoylglutathione lyase activity
TKWG_RS06655	COG0204	Acyl-transferase
TKWG_RS06660	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
TKWG_RS06665	COG0751	glycine-tRNA ligase activity
TKWG_RS06670	COG0752	glycyl-tRNA synthetase alpha subunit
TKWG_RS06700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TKWG_RS06705	COG0444	Belongs to the ABC transporter superfamily
TKWG_RS06710	COG4608	Belongs to the ABC transporter superfamily
TKWG_RS06720	COG0617	tRNA 3'-terminal CCA addition
TKWG_RS06735	COG0628	permease
TKWG_RS06745	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
TKWG_RS06755	COG0860	N-Acetylmuramoyl-L-alanine amidase
TKWG_RS06760	COG0802	atpase or kinase
TKWG_RS06770	COG4974	Belongs to the 'phage' integrase family
TKWG_RS06800	COG2188	Transcriptional regulator
TKWG_RS06805	COG1522	sequence-specific DNA binding
TKWG_RS06830	COG1074	ATP-dependent DNA helicase activity
TKWG_RS06840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
TKWG_RS06845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
TKWG_RS06860	COG0505	Belongs to the CarA family
TKWG_RS06865	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
TKWG_RS06875	COG0300	oxidoreductase activity
TKWG_RS06880	COG0406	alpha-ribazole phosphatase activity
TKWG_RS06890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
TKWG_RS06900	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
TKWG_RS06905	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
TKWG_RS06915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
TKWG_RS06950	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
TKWG_RS06960	COG0789	Transcriptional regulator
TKWG_RS06975	COG3486	L-lysine 6-monooxygenase (NADPH) activity
TKWG_RS07065	COG0671	phosphoesterase, PA-phosphatase related
TKWG_RS07120	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
TKWG_RS07125	COG2080	2 iron, 2 sulfur cluster binding
TKWG_RS07150	COG1454	alcohol dehydrogenase
TKWG_RS07165	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS07170	COG2030	dehydratase
TKWG_RS07170	COG1012	belongs to the aldehyde dehydrogenase family
TKWG_RS07195	COG5002	protein histidine kinase activity
TKWG_RS07200	COG1132	(ABC) transporter
TKWG_RS07225	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS07240	COG2863	cytochrome
TKWG_RS07245	COG0642	Histidine kinase
TKWG_RS07255	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
TKWG_RS07280	COG2010	Cytochrome c
TKWG_RS07335	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
TKWG_RS07390	COG0640	Transcriptional regulator
TKWG_RS07410	COG1024	Enoyl-CoA hydratase
TKWG_RS07435	COG0583	DNA-binding transcription factor activity
TKWG_RS07450	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS07455	COG0028	Belongs to the TPP enzyme family
TKWG_RS07470	COG0583	DNA-binding transcription factor activity
TKWG_RS07480	COG1733	regulation of RNA biosynthetic process
TKWG_RS07490	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
TKWG_RS07495	COG1414	Transcriptional regulator
TKWG_RS07510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TKWG_RS07545	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS07550	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
TKWG_RS07575	COG2814	Major facilitator Superfamily
TKWG_RS07580	COG0659	secondary active sulfate transmembrane transporter activity
TKWG_RS07595	COG0745	RESPONSE REGULATOR receiver
TKWG_RS07600	COG3321	synthase
TKWG_RS07600	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS07600	COG0604	alcohol dehydrogenase
TKWG_RS07605	COG0149	triose-phosphate isomerase activity
TKWG_RS07610	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TKWG_RS07620	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
TKWG_RS07625	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
TKWG_RS07630	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TKWG_RS07635	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TKWG_RS07640	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TKWG_RS07645	COG0649	NAD binding
TKWG_RS07660	COG1034	ATP synthesis coupled electron transport
TKWG_RS07670	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
TKWG_RS07680	COG0713	ATP synthesis coupled electron transport
TKWG_RS07695	COG1007	ATP synthesis coupled electron transport
TKWG_RS07725	COG0625	glutathione transferase activity
TKWG_RS07730	COG0560	Phosphoserine phosphatase
TKWG_RS07735	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
TKWG_RS07745	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
TKWG_RS07755	COG0450	alkyl hydroperoxide reductase
TKWG_RS07785	COG2814	Major facilitator Superfamily
TKWG_RS07805	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
TKWG_RS07810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TKWG_RS07820	COG2917	probably involved in intracellular septation
TKWG_RS07825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
TKWG_RS07840	COG0411	ABC transporter
TKWG_RS07860	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
TKWG_RS07865	COG2878	Part of a membrane complex involved in electron transport
TKWG_RS07885	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
TKWG_RS07890	COG0251	oxidation-reduction process
TKWG_RS07900	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
TKWG_RS07905	COG0133	tryptophan synthase activity
TKWG_RS07915	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
TKWG_RS07960	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
TKWG_RS07965	COG3023	N-Acetylmuramoyl-L-alanine amidase
TKWG_RS07975	COG0424	maF-like protein
TKWG_RS07985	COG0333	Belongs to the bacterial ribosomal protein bL32 family
TKWG_RS08010	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TKWG_RS08015	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TKWG_RS08040	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
TKWG_RS08050	COG0681	Belongs to the peptidase S26 family
TKWG_RS08055	COG0571	ribonuclease III activity
TKWG_RS08100	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
TKWG_RS08110	COG0583	DNA-binding transcription factor activity
TKWG_RS08135	COG0183	Belongs to the thiolase family
TKWG_RS08140	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS08195	COG2363	Small membrane protein
TKWG_RS08210	COG2855	membrane
TKWG_RS08220	COG0267	Belongs to the bacterial ribosomal protein bL33 family
TKWG_RS08255	COG3483	tryptophan 2,3-dioxygenase activity
TKWG_RS08265	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TKWG_RS08280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
TKWG_RS08285	COG0625	glutathione transferase activity
TKWG_RS08290	COG0424	maF-like protein
TKWG_RS08295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
TKWG_RS08300	COG0799	negative regulation of ribosome biogenesis
TKWG_RS08305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
TKWG_RS08320	COG0433	COG0433 Predicted ATPase
TKWG_RS08340	COG0667	Aldo Keto reductase
TKWG_RS08365	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
TKWG_RS08375	COG0277	FAD linked oxidase domain protein
TKWG_RS08380	COG0247	lactate metabolic process
TKWG_RS08385	COG0482	sulfurtransferase activity
TKWG_RS08395	COG3909	cytochrome
TKWG_RS08420	COG0069	glutamate synthase activity
TKWG_RS08430	COG2134	cdp-diacylglycerol pyrophosphatase
TKWG_RS08445	COG2732	(Barnase) inhibitor
TKWG_RS08455	COG2323	membrane
TKWG_RS08475	COG5002	protein histidine kinase activity
TKWG_RS08500	COG2951	lytic endotransglycosylase activity
TKWG_RS08520	COG1091	dTDP-4-dehydrorhamnose reductase activity
TKWG_RS08535	COG2885	chlorophyll binding
TKWG_RS08545	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
TKWG_RS08570	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
TKWG_RS08575	COG0287	Prephenate dehydrogenase
TKWG_RS08585	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
TKWG_RS08610	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
TKWG_RS08615	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
TKWG_RS08675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
TKWG_RS08720	COG2841	Protein conserved in bacteria
TKWG_RS08725	COG0628	permease
TKWG_RS08750	COG0556	nucleotide-excision repair
TKWG_RS08775	COG2137	regulation of response to DNA damage stimulus
TKWG_RS08780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
TKWG_RS08785	COG0583	DNA-binding transcription factor activity
TKWG_RS08805	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
TKWG_RS08810	COG0861	Integral membrane protein TerC family
TKWG_RS08815	COG0861	Integral membrane protein TerC family
TKWG_RS08820	COG0181	hydroxymethylbilane synthase activity
TKWG_RS08845	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
TKWG_RS08900	COG0425	Belongs to the sulfur carrier protein TusA family
TKWG_RS08905	COG0228	four-way junction DNA binding
TKWG_RS08910	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
TKWG_RS08915	COG0336	Belongs to the RNA methyltransferase TrmD family
TKWG_RS08920	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TKWG_RS08925	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
TKWG_RS08935	COG1104	cysteine desulfurase activity
TKWG_RS08940	COG0822	iron-sulfur transferase activity
TKWG_RS08945	COG0316	Belongs to the HesB IscA family
TKWG_RS08950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
TKWG_RS08955	COG0443	Heat shock 70 kDa protein
TKWG_RS08960	COG0633	Ferredoxin
TKWG_RS08970	COG0604	alcohol dehydrogenase
TKWG_RS09015	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
TKWG_RS09035	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS09040	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
TKWG_RS09075	COG2885	chlorophyll binding
TKWG_RS09075	COG3047	cAMP biosynthetic process
TKWG_RS09090	COG1136	(ABC) transporter
TKWG_RS09095	COG0084	hydrolase, TatD family'
TKWG_RS09115	COG0613	PHP domain protein
TKWG_RS09125	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
TKWG_RS09135	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
TKWG_RS09145	COG4181	ATPase activity
TKWG_RS09155	COG1758	RNA polymerase activity
TKWG_RS09160	COG0194	GDP metabolic process
TKWG_RS09165	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS09175	COG1561	YicC-like family, N-terminal region
TKWG_RS09180	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
TKWG_RS09185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
TKWG_RS09190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
TKWG_RS09210	COG3842	ATPase activity
TKWG_RS09220	COG1840	ABC-type Fe3 transport system, periplasmic component
TKWG_RS09235	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
TKWG_RS09250	COG3842	ATPase activity
TKWG_RS09255	COG0395	ABC-type sugar transport system, permease component
TKWG_RS09275	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
TKWG_RS09305	COG1999	signal sequence binding
TKWG_RS09310	COG0339	signal peptide processing
TKWG_RS09315	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
TKWG_RS09350	COG0285	dihydrofolate synthase activity
TKWG_RS09395	COG0024	Methionine aminopeptidase
TKWG_RS09400	COG0052	Belongs to the universal ribosomal protein uS2 family
TKWG_RS09405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
TKWG_RS09410	COG0528	UMP kinase activity
TKWG_RS09415	COG0233	cytoplasmic translational termination
TKWG_RS09420	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
TKWG_RS09425	COG0575	Belongs to the CDS family
TKWG_RS09430	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
TKWG_RS09435	COG0750	zinc metalloprotease
TKWG_RS09450	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TKWG_RS09460	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TKWG_RS09465	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TKWG_RS09470	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
TKWG_RS09480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TKWG_RS09510	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
TKWG_RS09515	COG2867	negative regulation of translational initiation
TKWG_RS09520	COG2914	Belongs to the UPF0125 (RnfH) family
TKWG_RS09535	COG0354	folic acid binding
TKWG_RS09540	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
TKWG_RS09545	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
TKWG_RS09555	COG0084	hydrolase, TatD family'
TKWG_RS09580	COG0625	glutathione transferase activity
TKWG_RS09585	COG0386	Belongs to the glutathione peroxidase family
TKWG_RS09590	COG5006	permease, DMT superfamily
TKWG_RS09595	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS09605	COG0583	DNA-binding transcription factor activity
TKWG_RS09610	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TKWG_RS09615	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TKWG_RS09635	COG3386	PFAM SMP-30 Gluconolaconase
TKWG_RS09645	COG1129	ABC transporter
TKWG_RS09655	COG1802	Transcriptional regulator
TKWG_RS09715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TKWG_RS09725	COG1764	response to oxidative stress
TKWG_RS09730	COG0583	DNA-binding transcription factor activity
TKWG_RS09755	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS09770	COG1006	Multisubunit Na H antiporter MnhC subunit
TKWG_RS09785	COG2212	antiporter activity
TKWG_RS09805	COG0778	Nitroreductase
TKWG_RS09810	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
TKWG_RS09850	COG0183	Belongs to the thiolase family
TKWG_RS09865	COG1187	pseudouridine synthase activity
TKWG_RS09870	COG3161	chorismate lyase activity
TKWG_RS09875	COG0347	Belongs to the P(II) protein family
TKWG_RS09890	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TKWG_RS09925	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
TKWG_RS09930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
TKWG_RS09935	COG2252	PERMEase
TKWG_RS09940	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TKWG_RS09955	COG1619	proteins homologs of microcin C7 resistance protein MccF
TKWG_RS09960	COG0590	tRNA wobble adenosine to inosine editing
TKWG_RS09975	COG1595	DNA-templated transcription, initiation
TKWG_RS10005	COG0519	Catalyzes the synthesis of GMP from XMP
TKWG_RS10005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
TKWG_RS10025	COG1686	Belongs to the peptidase S11 family
TKWG_RS10050	COG0210	DNA helicase
TKWG_RS10125	COG0546	phosphoglycolate phosphatase activity
TKWG_RS10145	COG3959	Transketolase, thiamine diphosphate binding domain
TKWG_RS10150	COG1802	Transcriptional regulator
TKWG_RS10160	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS10205	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS10210	COG2186	Transcriptional regulator
TKWG_RS10235	COG0776	regulation of translation
TKWG_RS10245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
TKWG_RS10250	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
TKWG_RS10255	COG0291	Belongs to the bacterial ribosomal protein bL35 family
TKWG_RS10265	COG2960	long-chain fatty acid transporting porin activity
TKWG_RS10285	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
TKWG_RS10290	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
TKWG_RS10305	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
TKWG_RS10340	COG0544	peptidyl-prolyl cis-trans isomerase activity
TKWG_RS10350	COG3258	Cytochrome c
TKWG_RS10355	COG2863	cytochrome
TKWG_RS10385	COG0829	nickel cation binding
TKWG_RS10390	COG0831	urea catabolic process
TKWG_RS10400	COG0832	Belongs to the urease beta subunit family
TKWG_RS10415	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
TKWG_RS10440	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
TKWG_RS10460	COG1278	Cold shock
TKWG_RS10490	COG1126	abc transporter atp-binding protein
TKWG_RS10495	COG0765	amino acid transport
TKWG_RS10510	COG2721	sulfolactate sulfo-lyase activity
TKWG_RS10535	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS10545	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS10570	COG1024	Enoyl-CoA hydratase
TKWG_RS10575	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS10620	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
TKWG_RS10625	COG0625	glutathione transferase activity
TKWG_RS10730	COG2135	peptidase activity
TKWG_RS10755	COG0582	viral genome integration into host DNA
TKWG_RS10860	COG0828	Belongs to the bacterial ribosomal protein bS21 family
TKWG_RS10880	COG0330	HflC and HflK could
TKWG_RS10885	COG0330	HflC and HflK could
TKWG_RS10890	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
TKWG_RS10895	COG1923	regulation of RNA biosynthetic process
TKWG_RS10910	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TKWG_RS10940	COG0105	UTP biosynthetic process
TKWG_RS10950	COG0656	L-ascorbic acid biosynthetic process
TKWG_RS10955	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS10980	COG5285	phytanoyl-CoA dioxygenase
TKWG_RS10995	COG0456	acetyltransferase
TKWG_RS11005	COG2207	Transcriptional regulator
TKWG_RS11025	COG0583	DNA-binding transcription factor activity
TKWG_RS11045	COG0596	Alpha beta hydrolase
TKWG_RS11070	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
TKWG_RS11085	COG3119	arylsulfatase activity
TKWG_RS11090	COG0583	DNA-binding transcription factor activity
TKWG_RS11145	COG0730	response to heat
TKWG_RS11155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
TKWG_RS11180	COG1024	Enoyl-CoA hydratase
TKWG_RS11195	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS11215	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
TKWG_RS11225	COG0583	DNA-binding transcription factor activity
TKWG_RS11240	COG2814	Major facilitator Superfamily
TKWG_RS11250	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
TKWG_RS11270	COG0583	DNA-binding transcription factor activity
TKWG_RS11290	COG0673	inositol 2-dehydrogenase activity
TKWG_RS11305	COG1335	isochorismatase
TKWG_RS11310	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
TKWG_RS11340	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS11350	COG0589	response to stress
TKWG_RS11360	COG0625	glutathione transferase activity
TKWG_RS11420	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
TKWG_RS11425	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS11430	COG0583	DNA-binding transcription factor activity
TKWG_RS11445	COG0697	spore germination
TKWG_RS11450	COG1285	pathogenesis
TKWG_RS11470	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
TKWG_RS11480	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
TKWG_RS11490	COG4948	Mandelate Racemase Muconate Lactonizing
TKWG_RS11580	COG2135	peptidase activity
TKWG_RS11590	COG1280	lysine exporter protein (LysE YggA)
TKWG_RS11610	COG0436	Aminotransferase
TKWG_RS11615	COG2171	N-acyltransferase activity
TKWG_RS11620	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
TKWG_RS11625	COG2890	protein-(glutamine-N5) methyltransferase activity
TKWG_RS11635	COG0135	phosphoribosylanthranilate isomerase activity
TKWG_RS11650	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TKWG_RS11675	COG0066	3-isopropylmalate dehydratase activity
TKWG_RS11685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TKWG_RS11700	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
TKWG_RS11705	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
TKWG_RS11740	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TKWG_RS11805	COG2086	electron transfer activity
TKWG_RS11830	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
TKWG_RS11845	COG0736	holo-[acyl-carrier-protein] synthase activity
TKWG_RS11855	COG0501	Belongs to the peptidase M48B family
TKWG_RS11865	COG2255	four-way junction helicase activity
TKWG_RS11870	COG0494	nUDIX hydrolase
TKWG_RS11875	COG0335	large ribosomal subunit rRNA binding
TKWG_RS11890	COG0450	alkyl hydroperoxide reductase
TKWG_RS11895	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS11915	COG0583	DNA-binding transcription factor activity
TKWG_RS11985	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
TKWG_RS12010	COG2070	2-Nitropropane dioxygenase
TKWG_RS12015	COG1671	Belongs to the UPF0178 family
TKWG_RS12020	COG2176	DNA-directed DNA polymerase activity
TKWG_RS12080	COG1733	regulation of RNA biosynthetic process
TKWG_RS12110	COG0196	riboflavin kinase activity
TKWG_RS12115	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
TKWG_RS12120	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
TKWG_RS12155	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
TKWG_RS12155	COG3008	intermembrane lipid transfer
TKWG_RS12160	COG2995	paraquat-inducible protein a
TKWG_RS12170	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
TKWG_RS12175	COG1278	Cold shock
TKWG_RS12190	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TKWG_RS12220	COG0563	adenylate kinase activity
TKWG_RS12235	COG0268	Binds directly to 16S ribosomal RNA
TKWG_RS12245	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
TKWG_RS12250	COG0137	argininosuccinate synthase activity
TKWG_RS12260	COG0642	Histidine kinase
TKWG_RS12270	COG0419	ATPase involved in DNA repair
TKWG_RS12275	COG0419	ATPase involved in DNA repair
TKWG_RS12305	COG2354	Protein conserved in bacteria
TKWG_RS12320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
TKWG_RS12345	COG4178	(ABC) transporter
TKWG_RS12355	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
TKWG_RS12360	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
TKWG_RS12365	COG4208	sulfate ABC transporter
TKWG_RS12380	COG0175	sulfate reduction
TKWG_RS12400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TKWG_RS12490	COG0859	PFAM glycosyl transferase family 9
TKWG_RS12500	COG1733	regulation of RNA biosynthetic process
TKWG_RS12505	COG1335	isochorismatase
TKWG_RS12510	COG0726	polysaccharide deacetylase
TKWG_RS12515	COG0438	transferase activity, transferring glycosyl groups
TKWG_RS12535	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
TKWG_RS12545	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
TKWG_RS12555	COG1177	transmembrane transport
TKWG_RS12570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
TKWG_RS12580	COG2346	COG2346, Truncated hemoglobins
TKWG_RS12585	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
TKWG_RS12590	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
TKWG_RS12610	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS12615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
TKWG_RS12620	COG1562	ergosterol biosynthetic process
TKWG_RS12630	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
TKWG_RS12670	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
TKWG_RS12680	COG0305	Participates in initiation and elongation during chromosome replication
TKWG_RS12685	COG0359	binds to the 23S rRNA
TKWG_RS12690	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
TKWG_RS12695	COG2965	DNA replication, synthesis of RNA primer
TKWG_RS12715	COG0142	geranyltranstransferase activity
TKWG_RS12720	COG1722	exodeoxyribonuclease VII activity
TKWG_RS12750	COG0583	DNA-binding transcription factor activity
TKWG_RS12760	COG0583	DNA-binding transcription factor activity
TKWG_RS12775	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TKWG_RS12775	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
TKWG_RS12780	COG1611	Belongs to the LOG family
TKWG_RS12795	COG2197	response regulator
TKWG_RS12815	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
TKWG_RS12820	COG1981	membrane
TKWG_RS12835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
TKWG_RS12845	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
TKWG_RS12860	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
TKWG_RS12865	COG0148	phosphopyruvate hydratase activity
TKWG_RS12880	COG0504	CTP synthase activity
TKWG_RS12890	COG0662	Cupin 2, conserved barrel domain protein
TKWG_RS12980	COG0464	growth
TKWG_RS12985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
TKWG_RS12990	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
TKWG_RS12995	COG3954	Phosphoribulokinase
TKWG_RS13010	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
TKWG_RS13015	COG3791	Glutathione-dependent formaldehyde-activating
TKWG_RS13035	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
TKWG_RS13040	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
TKWG_RS13050	COG0535	radical SAM domain protein
TKWG_RS13070	COG0456	acetyltransferase
TKWG_RS13085	COG1175	transmembrane transport
TKWG_RS13090	COG0395	ABC-type sugar transport system, permease component
TKWG_RS13105	COG2326	polyphosphate kinase activity
TKWG_RS13120	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
TKWG_RS13125	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
TKWG_RS13135	COG0195	Participates in both transcription termination and antitermination
TKWG_RS13135	COG2251	uridine kinase activity
TKWG_RS13145	COG1187	pseudouridine synthase activity
TKWG_RS13155	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
TKWG_RS13175	COG1522	sequence-specific DNA binding
TKWG_RS13190	COG0720	synthase
TKWG_RS13195	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS13205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TKWG_RS13260	COG3237	CsbD-like
TKWG_RS13275	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
TKWG_RS13280	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS13285	COG3243	poly(R)-hydroxyalkanoic acid synthase
TKWG_RS13305	COG1199	ATP-dependent helicase activity
TKWG_RS13310	COG2183	response to ionizing radiation
TKWG_RS13325	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS13330	COG5265	(ABC) transporter
TKWG_RS13335	COG4608	Belongs to the ABC transporter superfamily
TKWG_RS13340	COG0444	Belongs to the ABC transporter superfamily
TKWG_RS13345	COG0601	transmembrane transport
TKWG_RS13355	COG0747	negative chemotaxis
TKWG_RS13360	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
TKWG_RS13375	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
TKWG_RS13400	COG0372	Belongs to the citrate synthase family
TKWG_RS13410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
TKWG_RS13415	COG1053	succinate dehydrogenase
TKWG_RS13420	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
TKWG_RS13485	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TKWG_RS13510	COG1666	GTP binding
TKWG_RS13545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TKWG_RS13560	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TKWG_RS13610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
TKWG_RS13625	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS13635	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS13650	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS13660	COG2159	amidohydrolase
TKWG_RS13670	COG0583	DNA-binding transcription factor activity
TKWG_RS13710	COG1024	Enoyl-CoA hydratase
TKWG_RS13730	COG1802	Transcriptional regulator
TKWG_RS13745	COG0583	DNA-binding transcription factor activity
TKWG_RS13775	COG0825	malonyl-CoA metabolic process
TKWG_RS13805	COG1024	Enoyl-CoA hydratase
TKWG_RS13825	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TKWG_RS13845	COG1253	flavin adenine dinucleotide binding
TKWG_RS13850	COG0583	DNA-binding transcription factor activity
TKWG_RS13855	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS13860	COG2030	dehydratase
TKWG_RS13885	COG0668	transmembrane transport
TKWG_RS13890	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
TKWG_RS13905	COG1335	isochorismatase
TKWG_RS13910	COG1126	abc transporter atp-binding protein
TKWG_RS13915	COG0765	amino acid transport
TKWG_RS13925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS13945	COG2186	Transcriptional regulator
TKWG_RS13955	COG2850	peptidyl-arginine hydroxylation
TKWG_RS13965	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
TKWG_RS13970	COG0009	L-threonylcarbamoyladenylate synthase
TKWG_RS13995	COG0583	DNA-binding transcription factor activity
TKWG_RS14025	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TKWG_RS14045	COG3193	protein, possibly involved in utilization of glycolate and propanediol
TKWG_RS14050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
TKWG_RS14055	COG1185	polyribonucleotide nucleotidyltransferase activity
TKWG_RS14060	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
TKWG_RS14075	COG1183	phosphatidylcholine synthase activity
TKWG_RS14095	COG0765	amino acid transport
TKWG_RS14100	COG0765	amino acid transport
TKWG_RS14105	COG1126	abc transporter atp-binding protein
TKWG_RS14115	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TKWG_RS14125	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS14140	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS14150	COG2050	protein possibly involved in aromatic compounds catabolism
TKWG_RS14195	COG1126	abc transporter atp-binding protein
TKWG_RS14200	COG0765	amino acid transport
TKWG_RS14205	COG0765	amino acid transport
TKWG_RS14235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS14245	COG0440	acetolactate synthase activity
TKWG_RS14255	COG1289	transmembrane transporter activity
TKWG_RS14265	COG3022	response to hydroperoxide
TKWG_RS14270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
TKWG_RS14280	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
TKWG_RS14285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TKWG_RS14310	COG1054	Belongs to the UPF0176 family
TKWG_RS14320	COG3976	FMN-binding domain protein
TKWG_RS14320	COG0431	NADPH-dependent FMN reductase
TKWG_RS14320	COG1053	succinate dehydrogenase
TKWG_RS14335	COG0583	DNA-binding transcription factor activity
TKWG_RS14340	COG4948	Mandelate Racemase Muconate Lactonizing
TKWG_RS14390	COG4149	molybdate abc transporter
TKWG_RS14395	COG0725	ABC transporter, periplasmic molybdate-binding protein
TKWG_RS14410	COG0443	Heat shock 70 kDa protein
TKWG_RS14415	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
TKWG_RS14425	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
TKWG_RS14430	COG1420	regulation of RNA biosynthetic process
TKWG_RS14435	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
TKWG_RS14445	COG0735	belongs to the Fur family
TKWG_RS14480	COG0477	Major facilitator Superfamily
TKWG_RS14495	COG1845	cytochrome c oxidase, subunit III
TKWG_RS14505	COG3346	SURF1 family
TKWG_RS14515	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
TKWG_RS14555	COG0546	phosphoglycolate phosphatase activity
TKWG_RS14560	COG3842	ATPase activity
TKWG_RS14570	COG0395	ABC-type sugar transport system, permease component
TKWG_RS14575	COG1653	transport
TKWG_RS14585	COG1408	metallophosphoesterase
TKWG_RS14595	COG0531	amino acid
TKWG_RS14600	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
TKWG_RS14605	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TKWG_RS14630	COG2988	succinylglutamate desuccinylase activity
TKWG_RS14640	COG0583	DNA-binding transcription factor activity
TKWG_RS14650	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TKWG_RS14650	COG2169	Transcriptional regulator
TKWG_RS14660	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TKWG_RS14690	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
TKWG_RS14720	COG3186	Phenylalanine-4-hydroxylase
TKWG_RS14725	COG2154	pterin-4-alpha-carbinolamine dehydratase
TKWG_RS14740	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
TKWG_RS14745	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
TKWG_RS14760	COG1414	Transcriptional regulator
TKWG_RS14780	COG0513	Belongs to the DEAD box helicase family
TKWG_RS14805	COG0429	hydrolase of the alpha beta-hydrolase fold
TKWG_RS14820	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
TKWG_RS14850	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS14855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
TKWG_RS14865	COG2255	four-way junction helicase activity
TKWG_RS14890	COG0514	ATP-dependent DNA helicase (RecQ)
TKWG_RS14910	COG2022	thiamine diphosphate biosynthetic process
TKWG_RS14935	COG1120	ATPase activity
TKWG_RS14940	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TKWG_RS14945	COG4558	Periplasmic binding protein
TKWG_RS14950	COG3720	iron ion transport
TKWG_RS14955	COG4771	TonB-dependent receptor
TKWG_RS14955	COG1629	transport
TKWG_RS14965	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
TKWG_RS14975	COG1742	UPF0060 membrane protein
TKWG_RS15000	COG1129	ABC transporter
TKWG_RS15005	COG1137	ATPase activity
TKWG_RS15045	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
TKWG_RS15045	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TKWG_RS15065	COG1196	nuclear chromosome segregation
TKWG_RS15065	COG0739	heme binding
TKWG_RS15065	COG0741	lytic transglycosylase activity
TKWG_RS15075	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
TKWG_RS15090	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
TKWG_RS15100	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
TKWG_RS15125	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
TKWG_RS15135	COG3116	cell division
TKWG_RS15140	COG0275	rRNA processing
TKWG_RS15145	COG2001	Belongs to the MraZ family
TKWG_RS15155	COG4122	O-methyltransferase activity
TKWG_RS15160	COG0418	dihydroorotase activity
TKWG_RS15190	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS15215	COG4774	siderophore transport
TKWG_RS15220	COG1063	alcohol dehydrogenase
TKWG_RS15225	COG0477	Major facilitator Superfamily
TKWG_RS15235	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
TKWG_RS15240	COG1609	Transcriptional regulator
TKWG_RS15300	COG1858	cytochrome C peroxidase
TKWG_RS15335	COG0437	4 iron, 4 sulfur cluster binding
TKWG_RS15340	COG0348	domain, Protein
TKWG_RS15395	COG2084	Dehydrogenase
TKWG_RS15400	COG0494	nUDIX hydrolase
TKWG_RS15405	COG0442	prolyl-tRNA aminoacylation
TKWG_RS15410	COG0824	Thioesterase
TKWG_RS15420	COG0848	biopolymer transport protein
TKWG_RS15475	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS15480	COG1120	ATPase activity
TKWG_RS15500	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TKWG_RS15515	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
TKWG_RS15520	COG1294	oxidase, subunit
TKWG_RS15545	COG0235	Class ii aldolase
TKWG_RS15565	COG0431	NADPH-dependent FMN reductase
TKWG_RS15570	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
TKWG_RS15570	COG0778	Nitroreductase
TKWG_RS15590	COG1566	PFAM secretion protein HlyD family protein
TKWG_RS15630	COG1280	lysine exporter protein (LysE YggA)
TKWG_RS15660	COG2186	Transcriptional regulator
TKWG_RS15665	COG0179	Fumarylacetoacetate (FAA) hydrolase
TKWG_RS15690	COG0477	Major facilitator Superfamily
TKWG_RS15700	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
TKWG_RS15705	COG4172	Belongs to the ABC transporter superfamily
TKWG_RS15720	COG0747	negative chemotaxis
TKWG_RS15730	COG0028	Belongs to the TPP enzyme family
TKWG_RS15745	COG4176	ABC-type proline glycine betaine transport system permease component
TKWG_RS15750	COG3448	diguanylate cyclase activity
TKWG_RS15750	COG4175	Glycine betaine
TKWG_RS15770	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
TKWG_RS15775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TKWG_RS15780	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TKWG_RS15795	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS15810	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TKWG_RS15820	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
TKWG_RS15825	COG1120	ATPase activity
TKWG_RS15875	COG0745	RESPONSE REGULATOR receiver
TKWG_RS15885	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
TKWG_RS15905	COG0288	reversible hydration of carbon dioxide
TKWG_RS15910	COG0861	Integral membrane protein TerC family
TKWG_RS15915	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TKWG_RS15925	COG0019	diaminopimelate decarboxylase activity
TKWG_RS15940	COG1733	regulation of RNA biosynthetic process
TKWG_RS15945	COG0625	glutathione transferase activity
TKWG_RS16015	COG2080	2 iron, 2 sulfur cluster binding
TKWG_RS16020	COG2010	Cytochrome c
TKWG_RS16020	COG1529	Aldehyde oxidase and xanthine dehydrogenase
TKWG_RS16025	COG1846	Transcriptional regulator
TKWG_RS16070	COG0129	dihydroxy-acid dehydratase activity
TKWG_RS16090	COG2076	Multidrug Resistance protein
TKWG_RS16130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
TKWG_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS16165	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS16175	COG4670	ketone body catabolic process
TKWG_RS16180	COG1024	Enoyl-CoA hydratase
TKWG_RS16185	COG1053	succinate dehydrogenase
TKWG_RS16185	COG3976	FMN-binding domain protein
TKWG_RS16205	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS16215	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS16220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
TKWG_RS16260	COG1487	ribonuclease activity
TKWG_RS16265	COG4691	Plasmid stability protein
TKWG_RS16275	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
TKWG_RS16280	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
TKWG_RS16285	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TKWG_RS16310	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS16320	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS16360	COG0742	ribosomal rna small subunit methyltransferase
TKWG_RS16365	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
TKWG_RS16370	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
TKWG_RS16410	COG0346	lactoylglutathione lyase activity
TKWG_RS16425	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
TKWG_RS16485	COG0367	asparagine synthase
TKWG_RS16505	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
TKWG_RS16510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
TKWG_RS16520	COG1765	OsmC-like protein
TKWG_RS16535	COG1196	nuclear chromosome segregation
TKWG_RS16535	COG3264	Mechanosensitive ion channel
TKWG_RS16545	COG3842	ATPase activity
TKWG_RS16555	COG0395	ABC-type sugar transport system, permease component
TKWG_RS16570	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
TKWG_RS16570	COG1796	DNA polymerase
TKWG_RS16580	COG0509	glycine decarboxylation via glycine cleavage system
TKWG_RS16595	COG2081	HI0933 family
TKWG_RS16605	COG0717	Belongs to the dCTP deaminase family
TKWG_RS16640	COG0489	protein tyrosine kinase activity
TKWG_RS16675	COG1902	pentaerythritol trinitrate reductase activity
TKWG_RS16700	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TKWG_RS16700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
TKWG_RS16710	COG0220	tRNA (guanine-N7-)-methyltransferase activity
TKWG_RS16720	COG1652	LysM domain
TKWG_RS16740	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
TKWG_RS16750	COG3023	N-Acetylmuramoyl-L-alanine amidase
TKWG_RS16900	COG2207	Transcriptional regulator
TKWG_RS16915	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
TKWG_RS16945	COG0640	Transcriptional regulator
TKWG_RS16955	COG2207	Transcriptional regulator
TKWG_RS17000	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS17005	COG1309	transcriptional regulator
TKWG_RS17045	COG3119	arylsulfatase activity
TKWG_RS17055	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS17065	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TKWG_RS17070	COG1737	Transcriptional regulator
TKWG_RS17080	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
TKWG_RS17100	COG1715	Restriction endonuclease
TKWG_RS17115	COG3119	arylsulfatase activity
TKWG_RS17125	COG2267	carboxylic ester hydrolase activity
TKWG_RS17135	COG0583	DNA-binding transcription factor activity
TKWG_RS17145	COG3214	Protein conserved in bacteria
TKWG_RS17150	COG0583	DNA-binding transcription factor activity
TKWG_RS17155	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
TKWG_RS17155	COG1116	anion transmembrane transporter activity
TKWG_RS17160	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
TKWG_RS17205	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TKWG_RS17225	COG0477	Major facilitator Superfamily
TKWG_RS17230	COG0235	Class ii aldolase
TKWG_RS17250	COG3422	double-strand break repair
TKWG_RS17270	COG1764	response to oxidative stress
TKWG_RS17315	COG3210	domain, Protein
TKWG_RS17320	COG2831	hemolysin activation secretion protein
TKWG_RS17365	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS17370	COG0583	DNA-binding transcription factor activity
TKWG_RS17400	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS17420	COG0583	DNA-binding transcription factor activity
TKWG_RS17435	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TKWG_RS17440	COG0789	Transcriptional regulator
TKWG_RS17445	COG0778	Nitroreductase
TKWG_RS17455	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS17460	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS17510	COG0444	Belongs to the ABC transporter superfamily
TKWG_RS17515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
TKWG_RS17530	COG0583	DNA-binding transcription factor activity
TKWG_RS17550	COG0625	glutathione transferase activity
TKWG_RS17560	COG0604	alcohol dehydrogenase
TKWG_RS17585	COG2175	clavaminate synthase activity
TKWG_RS17605	COG1609	Transcriptional regulator
TKWG_RS17620	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS17635	COG0066	3-isopropylmalate dehydratase activity
TKWG_RS17640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
TKWG_RS17700	COG4771	TonB-dependent receptor
TKWG_RS17710	COG0583	DNA-binding transcription factor activity
TKWG_RS17715	COG0667	Aldo Keto reductase
TKWG_RS17730	COG0583	DNA-binding transcription factor activity
TKWG_RS17735	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS17785	COG0583	DNA-binding transcription factor activity
TKWG_RS17800	COG0066	3-isopropylmalate dehydratase activity
TKWG_RS17820	COG2271	Major facilitator Superfamily
TKWG_RS17840	COG1802	Transcriptional regulator
TKWG_RS17855	COG1309	transcriptional regulator
TKWG_RS17860	COG0655	NAD(P)H dehydrogenase (quinone) activity
TKWG_RS17870	COG4948	Mandelate Racemase Muconate Lactonizing
TKWG_RS17875	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
TKWG_RS17885	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS17890	COG1024	Enoyl-CoA hydratase
TKWG_RS17930	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS17945	COG1414	Transcriptional regulator
TKWG_RS17950	COG0159	tryptophan synthase activity
TKWG_RS17955	COG0133	tryptophan synthase activity
TKWG_RS17980	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
TKWG_RS17985	COG2207	Transcriptional regulator
TKWG_RS17985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TKWG_RS17995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TKWG_RS18005	COG1012	belongs to the aldehyde dehydrogenase family
TKWG_RS18010	COG1115	amino acid carrier protein
TKWG_RS18040	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
TKWG_RS18045	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
TKWG_RS18055	COG0693	protein deglycase activity
TKWG_RS18065	COG0438	transferase activity, transferring glycosyl groups
TKWG_RS18070	COG1525	nuclease
TKWG_RS18080	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS18085	COG1959	2 iron, 2 sulfur cluster binding
TKWG_RS18090	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
TKWG_RS18090	COG1017	nitric oxide dioxygenase activity
TKWG_RS18095	COG2860	membrane
TKWG_RS18100	COG1113	amino acid transport
TKWG_RS18105	COG0629	single-stranded DNA binding
TKWG_RS18115	COG1115	amino acid carrier protein
TKWG_RS18125	COG0748	coenzyme F420 binding
TKWG_RS18150	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
TKWG_RS18165	COG1414	Transcriptional regulator
TKWG_RS18175	COG0523	cobalamin synthesis protein
TKWG_RS18205	COG1414	Transcriptional regulator
TKWG_RS18220	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
TKWG_RS18225	COG4521	taurine ABC transporter
TKWG_RS18230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS18275	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS18280	COG4948	Mandelate Racemase Muconate Lactonizing
TKWG_RS18285	COG2186	Transcriptional regulator
TKWG_RS18315	COG2186	Transcriptional regulator
TKWG_RS18320	COG0730	response to heat
TKWG_RS18345	COG0789	Transcriptional regulator
TKWG_RS18360	COG2885	chlorophyll binding
TKWG_RS18380	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
TKWG_RS18395	COG0037	tRNA processing
TKWG_RS18400	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TKWG_RS18400	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
TKWG_RS18410	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
TKWG_RS18415	COG2890	protein-(glutamine-N5) methyltransferase activity
TKWG_RS18420	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
TKWG_RS18450	COG1201	RNA secondary structure unwinding
TKWG_RS18490	COG3395	kinase activity
TKWG_RS18510	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS18530	COG4619	ABC transporter
TKWG_RS18580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TKWG_RS18620	COG0534	Mate efflux family protein
TKWG_RS18625	COG0583	DNA-binding transcription factor activity
TKWG_RS18645	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
TKWG_RS18680	COG2217	Heavy metal translocating P-type atpase
TKWG_RS18695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS18715	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS18725	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS18730	COG1414	Transcriptional regulator
TKWG_RS18740	COG1250	3-hydroxyacyl-CoA dehydrogenase
TKWG_RS18740	COG1024	Enoyl-CoA hydratase
TKWG_RS18750	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
TKWG_RS18755	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS18765	COG2188	Transcriptional regulator
TKWG_RS18770	COG2721	sulfolactate sulfo-lyase activity
TKWG_RS18785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TKWG_RS18880	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
TKWG_RS18895	COG1596	polysaccharide export
TKWG_RS18915	COG2610	gluconate transmembrane transporter activity
TKWG_RS18930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
TKWG_RS18950	COG1176	ABC-type spermidine putrescine transport system, permease component I
TKWG_RS18990	COG2814	Major facilitator Superfamily
TKWG_RS19045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS19075	COG0583	DNA-binding transcription factor activity
TKWG_RS19080	COG1012	belongs to the aldehyde dehydrogenase family
TKWG_RS19085	COG0477	Major facilitator Superfamily
TKWG_RS19100	COG0436	Aminotransferase
TKWG_RS19110	COG2375	cellular response to nickel ion
TKWG_RS19115	COG1695	Transcriptional regulator
TKWG_RS19125	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
TKWG_RS19130	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS19175	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS19190	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
TKWG_RS19195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
TKWG_RS19230	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS19245	COG1764	response to oxidative stress
TKWG_RS19255	COG0583	DNA-binding transcription factor activity
TKWG_RS19270	COG1595	DNA-templated transcription, initiation
TKWG_RS19290	COG2814	Major facilitator Superfamily
TKWG_RS19310	COG0232	Belongs to the dGTPase family. Type 2 subfamily
TKWG_RS19320	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
TKWG_RS19330	COG1965	Belongs to the frataxin family
TKWG_RS19345	COG2175	clavaminate synthase activity
TKWG_RS19355	COG1116	anion transmembrane transporter activity
TKWG_RS19440	COG4232	protein-disulfide reductase activity
TKWG_RS19445	COG4232	protein-disulfide reductase activity
TKWG_RS19450	COG1324	tolerance protein
TKWG_RS19455	COG2814	Major facilitator Superfamily
TKWG_RS19465	COG0203	ribosomal protein L17
TKWG_RS19470	COG0202	RNA polymerase activity
TKWG_RS19475	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
TKWG_RS19480	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
TKWG_RS19485	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
TKWG_RS19495	COG0201	protein transport
TKWG_RS19500	COG0200	Binds to the 23S rRNA
TKWG_RS19505	COG1841	ribosomal large subunit assembly
TKWG_RS19510	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
TKWG_RS19515	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
TKWG_RS19525	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
TKWG_RS19530	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
TKWG_RS19535	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
TKWG_RS19540	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
TKWG_RS19545	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
TKWG_RS19555	COG3713	MltA-interacting MipA family protein
TKWG_RS19565	COG0395	ABC-type sugar transport system, permease component
TKWG_RS19570	COG1176	ABC-type spermidine putrescine transport system, permease component I
TKWG_RS19585	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
TKWG_RS19655	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS19705	COG0411	ABC transporter
TKWG_RS19710	COG0640	Transcriptional regulator
TKWG_RS19715	COG3832	glyoxalase III activity
TKWG_RS19730	COG3622	Belongs to the hyi family
TKWG_RS19735	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
TKWG_RS19740	COG0800	Aldolase
TKWG_RS19745	COG0277	FAD linked oxidase domain protein
TKWG_RS19750	COG0129	dihydroxy-acid dehydratase activity
TKWG_RS19755	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
TKWG_RS19765	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
TKWG_RS19770	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS19815	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
TKWG_RS19820	COG0800	Aldolase
TKWG_RS19825	COG3734	2-keto-3-deoxy-galactonokinase
TKWG_RS19830	COG0277	FAD linked oxidase domain protein
TKWG_RS19835	COG0277	FAD linked oxidase domain protein
TKWG_RS19850	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
TKWG_RS19855	COG0255	Belongs to the universal ribosomal protein uL29 family
TKWG_RS19860	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
TKWG_RS19865	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
TKWG_RS19870	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
TKWG_RS19880	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
TKWG_RS19885	COG0089	rRNA binding
TKWG_RS19890	COG0088	Forms part of the polypeptide exit tunnel
TKWG_RS19895	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
TKWG_RS19955	COG2308	Evidence 4 Homologs of previously reported genes of
TKWG_RS19965	COG2308	Evidence 4 Homologs of previously reported genes of
TKWG_RS19980	COG1322	Protein conserved in bacteria
TKWG_RS20010	COG2011	ABC-type metal ion transport system permease component
TKWG_RS20020	COG0051	transcription antitermination factor activity, RNA binding
TKWG_RS20030	COG0049	tRNA binding
TKWG_RS20035	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
TKWG_RS20050	COG0784	Response regulator, receiver
TKWG_RS20050	COG2205	protein histidine kinase activity
TKWG_RS20055	COG2301	Belongs to the HpcH HpaI aldolase family
TKWG_RS20065	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
TKWG_RS20085	COG1917	Cupin 2, conserved barrel domain protein
TKWG_RS20085	COG2169	Transcriptional regulator
TKWG_RS20100	COG3313	Fe-S protein
TKWG_RS20120	COG2818	Glycosylase
TKWG_RS20135	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS20140	COG1802	Transcriptional regulator
TKWG_RS20155	COG3246	L-lysine catabolic process to acetate
TKWG_RS20160	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS20185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
TKWG_RS20195	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
TKWG_RS20215	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
TKWG_RS20250	COG1028	Short-chain dehydrogenase reductase Sdr
TKWG_RS20255	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
TKWG_RS20280	COG2423	ornithine cyclodeaminase activity
TKWG_RS20295	COG2133	pyrroloquinoline quinone binding
TKWG_RS20300	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
TKWG_RS20305	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
TKWG_RS20315	COG0222	ribosome binding
TKWG_RS20320	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
TKWG_RS20330	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
TKWG_RS20340	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
TKWG_RS20370	COG1192	Involved in chromosome partitioning
TKWG_RS20375	COG0357	Ribosomal RNA small subunit methyltransferase G
TKWG_RS20385	COG0436	Aminotransferase
TKWG_RS20395	COG0537	adenosine 5'-monophosphoramidase activity
TKWG_RS20400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
TKWG_RS20405	COG0477	Major facilitator Superfamily
TKWG_RS20410	COG3180	Ammonia monooxygenase
TKWG_RS20440	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
TKWG_RS20460	COG0842	Transport permease protein
TKWG_RS20465	COG0842	Transport permease protein
TKWG_RS20470	COG1131	(ABC) transporter
TKWG_RS20495	COG0583	DNA-binding transcription factor activity
TKWG_RS20510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
TKWG_RS20510	COG1042	CoA-binding domain protein
TKWG_RS20510	COG0045	succinate-CoA ligase (ADP-forming) activity
TKWG_RS20515	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS20530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
TKWG_RS20540	COG0706	membrane insertase activity
TKWG_RS20545	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
TKWG_RS20550	COG0594	ribonuclease P activity
TKWG_RS20905	COG2010	Cytochrome c
TKWG_RS20910	COG4772	TonB-dependent receptor
TKWG_RS20915	COG4772	TonB-dependent receptor
TKWG_RS20930	COG0210	DNA helicase
TKWG_RS20955	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS20970	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
TKWG_RS20990	COG2814	Major facilitator Superfamily
TKWG_RS20995	COG2814	Major facilitator Superfamily
TKWG_RS21020	COG0792	nuclease activity
TKWG_RS21030	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS21035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
TKWG_RS21050	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
TKWG_RS21050	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
TKWG_RS21075	COG0793	Belongs to the peptidase S41A family
TKWG_RS21080	COG0793	Belongs to the peptidase S41A family
TKWG_RS21095	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
TKWG_RS21155	COG0039	L-malate dehydrogenase activity
TKWG_RS21255	COG0850	regulation of cytokinetic process
TKWG_RS21265	COG0850	regulation of cytokinetic process
TKWG_RS21305	COG1404	Belongs to the peptidase S8 family
TKWG_RS21350	COG1804	L-carnitine dehydratase bile acid-inducible protein F
TKWG_RS21365	COG1214	PFAM Peptidase M22, glycoprotease
TKWG_RS21375	COG0456	acetyltransferase
TKWG_RS21380	COG1573	uracil-dna glycosylase
TKWG_RS21390	COG2003	Belongs to the UPF0758 family
TKWG_RS21405	COG2205	protein histidine kinase activity
TKWG_RS21445	COG1609	Transcriptional regulator
TKWG_RS21450	COG1609	Transcriptional regulator
TKWG_RS21475	COG2863	cytochrome
TKWG_RS21505	COG0318	PFAM AMP-dependent synthetase and ligase
TKWG_RS21530	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TKWG_RS21565	COG1295	ribonuclease BN
TKWG_RS21570	COG1295	ribonuclease BN
TKWG_RS21575	COG0038	chloride channel
TKWG_RS21585	COG0038	chloride channel
TKWG_RS21605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
TKWG_RS21605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
TKWG_RS21610	COG3008	intermembrane lipid transfer
TKWG_RS21645	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS21650	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS21670	COG0156	8-amino-7-oxononanoate synthase activity
TKWG_RS21675	COG0156	8-amino-7-oxononanoate synthase activity
TKWG_RS21680	COG0156	8-amino-7-oxononanoate synthase activity
TKWG_RS21700	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
TKWG_RS21705	COG0679	Auxin Efflux Carrier
TKWG_RS21720	COG3181	Tripartite tricarboxylate transporter family receptor
TKWG_RS21735	COG1960	acyl-CoA dehydrogenase activity
TKWG_RS21750	COG2005	Transcriptional regulator
TKWG_RS21750	COG3585	molybdate ion transport
TKWG_RS21755	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
TKWG_RS21810	COG0583	DNA-binding transcription factor activity
TKWG_RS21845	COG1737	Transcriptional regulator
TKWG_RS21935	COG0745	RESPONSE REGULATOR receiver
TKWG_RS21960	COG4206	TonB-dependent receptor
TKWG_RS22005	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
TKWG_RS22010	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
TKWG_RS22045	COG1322	Protein conserved in bacteria