locus-tag	class	description
MIM_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIM_RS00025	COG1917	Cupin 2, conserved barrel domain protein
MIM_RS00025	COG2207	Transcriptional regulator
MIM_RS00060	COG4574	serine-type endopeptidase inhibitor activity
MIM_RS00070	COG2080	2 iron, 2 sulfur cluster binding
MIM_RS00075	COG1181	Belongs to the D-alanine--D-alanine ligase family
MIM_RS00100	COG0583	DNA-binding transcription factor activity
MIM_RS00105	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS00110	COG1733	regulation of RNA biosynthetic process
MIM_RS00120	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_RS00130	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MIM_RS00135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_RS00145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS00155	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS00195	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_RS00200	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS00230	COG2011	ABC-type metal ion transport system permease component
MIM_RS00235	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MIM_RS00240	COG1464	Belongs to the NlpA lipoprotein family
MIM_RS00250	COG0477	Major facilitator Superfamily
MIM_RS00275	COG0028	Belongs to the TPP enzyme family
MIM_RS00295	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS00300	COG2186	Transcriptional regulator
MIM_RS00315	COG0395	ABC-type sugar transport system, permease component
MIM_RS00320	COG3842	ATPase activity
MIM_RS00355	COG4585	Histidine kinase
MIM_RS00375	COG4669	(LipO)protein
MIM_RS00390	COG1157	protein secretion by the type III secretion system
MIM_RS00405	COG4790	Type iii secretion
MIM_RS00415	COG4791	protein targeting
MIM_RS00420	COG4792	protein secretion
MIM_RS00440	COG4789	Type iii secretion
MIM_RS00445	COG4964	Belongs to the GSP D family
MIM_RS00485	COG0583	DNA-binding transcription factor activity
MIM_RS00490	COG2814	Major facilitator Superfamily
MIM_RS00495	COG2814	Major facilitator Superfamily
MIM_RS00500	COG4774	siderophore transport
MIM_RS00505	COG0625	glutathione transferase activity
MIM_RS00510	COG1733	regulation of RNA biosynthetic process
MIM_RS00520	COG0488	(ABC) transporter
MIM_RS00535	COG5285	phytanoyl-CoA dioxygenase
MIM_RS00540	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_RS00545	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS00550	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_RS00580	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIM_RS00595	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS00615	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_RS00630	COG0410	ABC transporter
MIM_RS00635	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
MIM_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS00655	COG5339	Protein conserved in bacteria
MIM_RS00660	COG0251	oxidation-reduction process
MIM_RS00670	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS00675	COG3257	ureidoglycine aminohydrolase activity
MIM_RS00680	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
MIM_RS00685	COG1301	dicarboxylic acid transport
MIM_RS00705	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
MIM_RS00710	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
MIM_RS00725	COG0583	DNA-binding transcription factor activity
MIM_RS00730	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS00745	COG0673	inositol 2-dehydrogenase activity
MIM_RS00770	COG0590	tRNA wobble adenosine to inosine editing
MIM_RS00775	COG2807	transmembrane transport
MIM_RS00785	COG0583	DNA-binding transcription factor activity
MIM_RS00790	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS00795	COG0431	NADPH-dependent FMN reductase
MIM_RS00800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_RS00805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS00815	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS00820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS00830	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS00845	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MIM_RS00855	COG3473	Maleate cis-trans isomerase
MIM_RS00880	COG1573	uracil-dna glycosylase
MIM_RS00895	COG2814	Major facilitator Superfamily
MIM_RS00900	COG0583	DNA-binding transcription factor activity
MIM_RS00905	COG1609	Transcriptional regulator
MIM_RS00930	COG0861	Integral membrane protein TerC family
MIM_RS00935	COG2119	membrane
MIM_RS00950	COG4771	TonB-dependent receptor
MIM_RS00960	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS00965	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
MIM_RS00970	COG1132	(ABC) transporter
MIM_RS00970	COG2375	cellular response to nickel ion
MIM_RS00990	COG2814	Major facilitator Superfamily
MIM_RS01030	COG2010	Cytochrome c
MIM_RS01030	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_RS01040	COG0683	leucine binding
MIM_RS01045	COG0559	Belongs to the binding-protein-dependent transport system permease family
MIM_RS01065	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_RS01070	COG0596	Alpha beta hydrolase
MIM_RS01075	COG2309	aminopeptidase activity
MIM_RS01080	COG1335	isochorismatase
MIM_RS01085	COG1309	transcriptional regulator
MIM_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS01100	COG1230	cation diffusion facilitator family transporter
MIM_RS01125	COG2223	nitrite transmembrane transporter activity
MIM_RS01130	COG2207	Transcriptional regulator
MIM_RS01140	COG5383	Protein conserved in bacteria
MIM_RS01145	COG4607	ABC-type enterochelin transport system periplasmic component
MIM_RS01150	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS01155	COG4605	iron ion homeostasis
MIM_RS01160	COG4604	ABC transporter, ATP-binding protein
MIM_RS01165	COG0668	transmembrane transport
MIM_RS01170	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS01185	COG3284	Transcriptional regulator
MIM_RS01190	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS01200	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_RS01210	COG3608	succinylglutamate desuccinylase aspartoacylase
MIM_RS01210	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
MIM_RS01225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
MIM_RS01260	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_RS01265	COG3189	MarR family transcriptional regulator
MIM_RS01270	COG4993	Dehydrogenase
MIM_RS01275	COG4772	TonB-dependent receptor
MIM_RS01280	COG1414	Transcriptional regulator
MIM_RS01285	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_RS01290	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS01310	COG1560	Kdo2-lipid A biosynthetic process
MIM_RS01315	COG0432	Pfam Uncharacterised protein family UPF0047
MIM_RS01330	COG0583	DNA-binding transcription factor activity
MIM_RS01350	COG1131	(ABC) transporter
MIM_RS01355	COG0842	Transport permease protein
MIM_RS01375	COG4176	ABC-type proline glycine betaine transport system permease component
MIM_RS01400	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS01420	COG2129	metallophosphoesterase
MIM_RS01445	COG4166	transmembrane transport
MIM_RS01450	COG0444	Belongs to the ABC transporter superfamily
MIM_RS01455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS01460	COG0601	transmembrane transport
MIM_RS01465	COG4608	Belongs to the ABC transporter superfamily
MIM_RS01470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIM_RS01490	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
MIM_RS01495	COG2161	toxin-antitoxin pair type II binding
MIM_RS01500	COG4115	mRNA cleavage
MIM_RS01535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
MIM_RS01540	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
MIM_RS01555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_RS01565	COG5339	Protein conserved in bacteria
MIM_RS01580	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
MIM_RS01585	COG0028	Belongs to the TPP enzyme family
MIM_RS01600	COG2072	flavoprotein involved in K transport
MIM_RS01605	COG0601	transmembrane transport
MIM_RS01610	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS01615	COG0444	Belongs to the ABC transporter superfamily
MIM_RS01620	COG4608	Belongs to the ABC transporter superfamily
MIM_RS01625	COG0747	negative chemotaxis
MIM_RS01665	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIM_RS01680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIM_RS01685	COG2922	Belongs to the Smg family
MIM_RS01690	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
MIM_RS01705	COG4770	biotin carboxylase activity
MIM_RS01710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
MIM_RS01715	COG0183	Belongs to the thiolase family
MIM_RS01720	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
MIM_RS01725	COG1960	acyl-CoA dehydrogenase activity
MIM_RS01735	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIM_RS01740	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_RS01760	COG1960	acyl-CoA dehydrogenase activity
MIM_RS01775	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS01785	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS01790	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS01795	COG1024	Enoyl-CoA hydratase
MIM_RS01800	COG2188	Transcriptional regulator
MIM_RS01805	COG1280	lysine exporter protein (LysE YggA)
MIM_RS01815	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
MIM_RS01825	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
MIM_RS01835	COG0018	arginyl-trna synthetase
MIM_RS01850	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_RS01860	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
MIM_RS01870	COG2193	ferroxidase activity
MIM_RS01880	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MIM_RS01890	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
MIM_RS01895	COG0583	DNA-binding transcription factor activity
MIM_RS01900	COG2986	histidine ammonia-lyase
MIM_RS01930	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
MIM_RS01940	COG1160	GTP binding
MIM_RS01980	COG3842	ATPase activity
MIM_RS01985	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIM_RS01995	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIM_RS01995	COG0678	peroxiredoxin activity
MIM_RS02000	COG2431	L-lysine efflux transmembrane transporter activity
MIM_RS02020	COG4160	amino acid transport
MIM_RS02025	COG4598	ABC transporter
MIM_RS02030	COG0730	response to heat
MIM_RS02040	COG3045	CreA protein
MIM_RS02050	COG0405	Gamma-glutamyltransferase
MIM_RS02075	COG2175	clavaminate synthase activity
MIM_RS02080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS02085	COG1116	anion transmembrane transporter activity
MIM_RS02095	COG2175	clavaminate synthase activity
MIM_RS02100	COG1741	Belongs to the pirin family
MIM_RS02135	COG3038	cytochrome b561
MIM_RS02165	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS02210	COG1309	transcriptional regulator
MIM_RS02215	COG0697	spore germination
MIM_RS02220	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIM_RS02225	COG1127	ABC transporter
MIM_RS02240	COG2079	MmgE PrpD family protein
MIM_RS02265	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_RS02270	COG0066	3-isopropylmalate dehydratase activity
MIM_RS02290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_RS02295	COG0066	3-isopropylmalate dehydratase activity
MIM_RS02300	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS02310	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS02335	COG1522	sequence-specific DNA binding
MIM_RS02345	COG0463	Glycosyl transferase, family 2
MIM_RS02350	COG2814	Major facilitator Superfamily
MIM_RS02355	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MIM_RS02365	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
MIM_RS02375	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIM_RS02405	COG1612	heme a metabolic process
MIM_RS02410	COG0109	protoheme IX farnesyltransferase activity
MIM_RS02415	COG1999	signal sequence binding
MIM_RS02425	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MIM_RS02430	COG4521	taurine ABC transporter
MIM_RS02435	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MIM_RS02440	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS02455	COG1368	sulfuric ester hydrolase activity
MIM_RS02460	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MIM_RS02465	COG0513	Belongs to the DEAD box helicase family
MIM_RS02470	COG0069	glutamate synthase activity
MIM_RS02470	COG0067	glutamate synthase
MIM_RS02470	COG0070	glutamate synthase
MIM_RS02480	COG1127	ABC transporter
MIM_RS02485	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
MIM_RS02490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIM_RS02495	COG2853	Lipoprotein
MIM_RS02505	COG1131	(ABC) transporter
MIM_RS02510	COG0842	Transport permease protein
MIM_RS02515	COG0271	Belongs to the BolA IbaG family
MIM_RS02520	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MIM_RS02525	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
MIM_RS02530	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIM_RS02535	COG0131	Imidazoleglycerol-phosphate dehydratase
MIM_RS02545	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
MIM_RS02550	COG0107	imidazoleglycerol-phosphate synthase activity
MIM_RS02555	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
MIM_RS02560	COG0140	phosphoribosyl-ATP diphosphatase activity
MIM_RS02565	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
MIM_RS02575	COG0805	protein transport
MIM_RS02580	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIM_RS02585	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MIM_RS02590	COG1970	mechanosensitive ion channel activity
MIM_RS02595	COG0723	plastoquinol--plastocyanin reductase activity
MIM_RS02600	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
MIM_RS02605	COG2857	Cytochrome c1
MIM_RS02610	COG0625	glutathione transferase activity
MIM_RS02615	COG2969	positive regulation of protein catabolic process
MIM_RS02625	COG2096	Adenosyltransferase
MIM_RS02635	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
MIM_RS02640	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
MIM_RS02650	COG0523	cobalamin synthesis protein
MIM_RS02655	COG0735	belongs to the Fur family
MIM_RS02665	COG1121	(ABC) transporter
MIM_RS02670	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MIM_RS02675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
MIM_RS02685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
MIM_RS02690	COG1560	Kdo2-lipid A biosynthetic process
MIM_RS02695	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MIM_RS02700	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
MIM_RS02705	COG1950	PFAM Membrane protein of
MIM_RS02710	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
MIM_RS02715	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MIM_RS02725	COG0617	tRNA 3'-terminal CCA addition
MIM_RS02765	COG0513	Belongs to the DEAD box helicase family
MIM_RS02775	COG0134	indole-3-glycerol-phosphate synthase activity
MIM_RS02780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
MIM_RS02785	COG0512	Glutamine amidotransferase of anthranilate synthase
MIM_RS02795	COG0546	phosphoglycolate phosphatase activity
MIM_RS02800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MIM_RS02805	COG2967	ApaG domain
MIM_RS02815	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_RS02830	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIM_RS02840	COG2823	Periplasmic or secreted lipoprotein
MIM_RS02845	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
MIM_RS02850	COG0792	nuclease activity
MIM_RS02865	COG1660	Displays ATPase and GTPase activities
MIM_RS02870	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MIM_RS02880	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
MIM_RS02885	COG1137	ATPase activity
MIM_RS02900	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
MIM_RS02910	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
MIM_RS02915	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MIM_RS02920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
MIM_RS02925	COG1238	metal cluster binding
MIM_RS02935	COG1984	allophanate hydrolase subunit 2
MIM_RS02940	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
MIM_RS02955	COG2226	methyltransferase
MIM_RS02965	COG1116	anion transmembrane transporter activity
MIM_RS02990	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
MIM_RS02995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MIM_RS03010	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
MIM_RS03015	COG0351	phosphomethylpyrimidine kinase
MIM_RS03020	COG2326	polyphosphate kinase activity
MIM_RS03040	COG0791	NLP P60 protein
MIM_RS03045	COG1902	pentaerythritol trinitrate reductase activity
MIM_RS03050	COG1737	Transcriptional regulator
MIM_RS03060	COG4172	Belongs to the ABC transporter superfamily
MIM_RS03065	COG0747	negative chemotaxis
MIM_RS03070	COG0601	transmembrane transport
MIM_RS03095	COG1794	racemase activity, acting on amino acids and derivatives
MIM_RS03105	COG0583	DNA-binding transcription factor activity
MIM_RS03115	COG3386	PFAM SMP-30 Gluconolaconase
MIM_RS03130	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS03140	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MIM_RS03145	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MIM_RS03150	COG3639	organic phosphonate transmembrane transporter activity
MIM_RS03155	COG2188	Transcriptional regulator
MIM_RS03160	COG3624	Phosphonate C-P lyase system protein PhnG
MIM_RS03170	COG3626	phosphonate metabolism
MIM_RS03175	COG3627	carbon phosphorus lyase activity
MIM_RS03180	COG4107	phosphonate C-P lyase system protein PhnK
MIM_RS03185	COG4778	phosphonate C-P lyase system protein PhnL
MIM_RS03190	COG3454	Phosphonate metabolism
MIM_RS03200	COG1234	tRNA 3'-trailer cleavage
MIM_RS03215	COG0672	)-iron permease
MIM_RS03225	COG0668	transmembrane transport
MIM_RS03245	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS03250	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
MIM_RS03260	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS03280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_RS03290	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS03295	COG0473	3-isopropylmalate dehydrogenase activity
MIM_RS03305	COG0252	asparaginase activity
MIM_RS03310	COG0667	Aldo Keto reductase
MIM_RS03320	COG0145	ligase activity
MIM_RS03325	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
MIM_RS03330	COG4647	ligase activity
MIM_RS03335	COG2610	gluconate transmembrane transporter activity
MIM_RS03350	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIM_RS03410	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_RS03415	COG0506	proline dehydrogenase activity
MIM_RS03415	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIM_RS03415	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
MIM_RS03420	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
MIM_RS03425	COG1956	GAF domain-containing protein
MIM_RS03440	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MIM_RS03445	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS03460	COG2321	neutral zinc metallopeptidase
MIM_RS03470	COG1994	Peptidase M50
MIM_RS03475	COG3568	Endonuclease Exonuclease Phosphatase
MIM_RS03480	COG0859	PFAM glycosyl transferase family 9
MIM_RS03490	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MIM_RS03490	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MIM_RS03495	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
MIM_RS03500	COG2945	thiolester hydrolase activity
MIM_RS03505	COG1686	Belongs to the peptidase S11 family
MIM_RS03515	COG2921	Belongs to the UPF0250 family
MIM_RS03525	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
MIM_RS03535	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MIM_RS03540	COG0438	transferase activity, transferring glycosyl groups
MIM_RS03545	COG0166	Belongs to the GPI family
MIM_RS03550	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
MIM_RS03560	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
MIM_RS03565	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_RS03595	COG0297	glycogen (starch) synthase activity
MIM_RS03615	COG1946	Acyl-CoA thioesterase
MIM_RS03630	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
MIM_RS03675	COG0095	Lipoate-protein ligase
MIM_RS03680	COG0242	peptide deformylase activity
MIM_RS03685	COG0758	DNA mediated transformation
MIM_RS03690	COG0431	NADPH-dependent FMN reductase
MIM_RS03710	COG0477	Major facilitator Superfamily
MIM_RS03720	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MIM_RS03725	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
MIM_RS03730	COG0546	phosphoglycolate phosphatase activity
MIM_RS03735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
MIM_RS03750	COG5000	phosphorelay sensor kinase activity
MIM_RS03755	COG2204	response regulator
MIM_RS03765	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
MIM_RS03770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
MIM_RS03775	COG0010	Belongs to the arginase family
MIM_RS03785	COG0765	amino acid transport
MIM_RS03790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS03800	COG1040	competence protein
MIM_RS03805	COG2226	methyltransferase
MIM_RS03810	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MIM_RS03815	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
MIM_RS03820	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MIM_RS03825	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MIM_RS03830	COG0588	phosphoglycerate mutase activity
MIM_RS03835	COG4942	peptidase
MIM_RS03840	COG0793	Belongs to the peptidase S41A family
MIM_RS03855	COG1024	Enoyl-CoA hydratase
MIM_RS03865	COG0356	it plays a direct role in the translocation of protons across the membrane
MIM_RS03880	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MIM_RS03885	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
MIM_RS03890	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MIM_RS03900	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MIM_RS03905	COG1473	amidohydrolase
MIM_RS03920	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS03935	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
MIM_RS03940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MIM_RS04005	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
MIM_RS04045	COG2003	Belongs to the UPF0758 family
MIM_RS04050	COG3657	addiction module killer protein
MIM_RS04055	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIM_RS04060	COG3077	Addiction module antitoxin, RelB DinJ family
MIM_RS04070	COG1132	(ABC) transporter
MIM_RS04075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_RS04085	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS04090	COG0583	DNA-binding transcription factor activity
MIM_RS04095	COG1917	Cupin 2, conserved barrel domain protein
MIM_RS04095	COG4977	sequence-specific DNA binding
MIM_RS04105	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
MIM_RS04105	COG2885	chlorophyll binding
MIM_RS04110	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MIM_RS04165	COG0601	transmembrane transport
MIM_RS04170	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS04175	COG4608	Belongs to the ABC transporter superfamily
MIM_RS04180	COG0444	Belongs to the ABC transporter superfamily
MIM_RS04190	COG0154	amidase activity
MIM_RS04195	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_RS04200	COG0477	Major facilitator Superfamily
MIM_RS04215	COG0252	asparaginase activity
MIM_RS04235	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_RS04240	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_RS04250	COG1850	ribulose-bisphosphate carboxylase activity
MIM_RS04260	COG3360	Dodecin
MIM_RS04280	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS04290	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS04300	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_RS04305	COG0765	amino acid transport
MIM_RS04310	COG0765	amino acid transport
MIM_RS04315	COG1126	abc transporter atp-binding protein
MIM_RS04340	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_RS04350	COG0753	catalase activity
MIM_RS04375	COG0583	DNA-binding transcription factor activity
MIM_RS04385	COG0436	Aminotransferase
MIM_RS04390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS04400	COG0765	amino acid transport
MIM_RS04405	COG1126	abc transporter atp-binding protein
MIM_RS04410	COG0583	DNA-binding transcription factor activity
MIM_RS04420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS04435	COG1024	Enoyl-CoA hydratase
MIM_RS04440	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS04450	COG1024	Enoyl-CoA hydratase
MIM_RS04455	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS04460	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_RS04465	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS04470	COG0251	oxidation-reduction process
MIM_RS04490	COG1177	transmembrane transport
MIM_RS04495	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_RS04500	COG3842	ATPase activity
MIM_RS04525	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS04540	COG1301	dicarboxylic acid transport
MIM_RS04550	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS04560	COG4160	amino acid transport
MIM_RS04580	COG2918	glutathione biosynthetic process
MIM_RS04590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIM_RS04595	COG2813	Specifically methylates the guanine in position
MIM_RS04595	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
MIM_RS04600	COG2223	nitrite transmembrane transporter activity
MIM_RS04610	COG2010	Cytochrome c
MIM_RS04625	COG3384	dioxygenase
MIM_RS04630	COG2259	Doxx family
MIM_RS04635	COG0583	DNA-binding transcription factor activity
MIM_RS04640	COG2375	cellular response to nickel ion
MIM_RS04640	COG1132	(ABC) transporter
MIM_RS04645	COG1132	(ABC) transporter
MIM_RS04660	COG4773	Receptor
MIM_RS04670	COG4774	siderophore transport
MIM_RS04675	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MIM_RS04680	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIM_RS04685	COG0154	amidase activity
MIM_RS04690	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MIM_RS04695	COG1077	Cell shape determining protein MreB Mrl
MIM_RS04700	COG1792	Involved in formation and maintenance of cell shape
MIM_RS04710	COG0768	penicillin binding
MIM_RS04715	COG0772	Belongs to the SEDS family
MIM_RS04720	COG1194	a g-specific adenine glycosylase
MIM_RS04725	COG2177	Part of the ABC transporter FtsEX involved in
MIM_RS04730	COG2884	Cell division ATP-binding protein ftsE
MIM_RS04735	COG4597	amino acid ABC transporter
MIM_RS04740	COG0765	amino acid transport
MIM_RS04745	COG1126	abc transporter atp-binding protein
MIM_RS04755	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MIM_RS04760	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
MIM_RS04765	COG2197	response regulator
MIM_RS04790	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
MIM_RS04795	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIM_RS04815	COG1045	serine acetyltransferase
MIM_RS04820	COG0494	nUDIX hydrolase
MIM_RS04830	COG0142	geranyltranstransferase activity
MIM_RS04835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS04840	COG0765	amino acid transport
MIM_RS04845	COG1126	abc transporter atp-binding protein
MIM_RS04850	COG0129	dihydroxy-acid dehydratase activity
MIM_RS04860	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
MIM_RS04875	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
MIM_RS04885	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_RS04890	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS04895	COG1116	anion transmembrane transporter activity
MIM_RS04900	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIM_RS04910	COG0243	molybdopterin cofactor binding
MIM_RS04920	COG0745	RESPONSE REGULATOR receiver
MIM_RS04925	COG2205	protein histidine kinase activity
MIM_RS04930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIM_RS04945	COG1609	Transcriptional regulator
MIM_RS04950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
MIM_RS04955	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS04960	COG0477	Major facilitator Superfamily
MIM_RS04965	COG1063	alcohol dehydrogenase
MIM_RS04985	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS04995	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS05010	COG0418	dihydroorotase activity
MIM_RS05015	COG4122	O-methyltransferase activity
MIM_RS05020	COG0488	(ABC) transporter
MIM_RS05025	COG2001	Belongs to the MraZ family
MIM_RS05030	COG0275	rRNA processing
MIM_RS05035	COG3116	cell division
MIM_RS05045	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
MIM_RS05050	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIM_RS05055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MIM_RS05065	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MIM_RS05070	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIM_RS05075	COG1181	Belongs to the D-alanine--D-alanine ligase family
MIM_RS05080	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MIM_RS05095	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
MIM_RS05105	COG0739	heme binding
MIM_RS05105	COG1196	nuclear chromosome segregation
MIM_RS05105	COG0741	lytic transglycosylase activity
MIM_RS05110	COG0653	protein targeting
MIM_RS05115	COG2239	Acts as a magnesium transporter
MIM_RS05125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS05125	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
MIM_RS05175	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS05180	COG4206	TonB-dependent receptor
MIM_RS05190	COG4558	Periplasmic binding protein
MIM_RS05195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS05200	COG1120	ATPase activity
MIM_RS05205	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIM_RS05220	COG2022	thiamine diphosphate biosynthetic process
MIM_RS05240	COG0514	ATP-dependent DNA helicase (RecQ)
MIM_RS05265	COG2255	four-way junction helicase activity
MIM_RS05270	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MIM_RS05270	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_RS05275	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MIM_RS05280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_RS05290	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
MIM_RS05310	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_RS05325	COG0429	hydrolase of the alpha beta-hydrolase fold
MIM_RS05350	COG0513	Belongs to the DEAD box helicase family
MIM_RS05370	COG1414	Transcriptional regulator
MIM_RS05385	COG0167	dihydroorotate dehydrogenase activity
MIM_RS05390	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
MIM_RS05395	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
MIM_RS05410	COG2154	pterin-4-alpha-carbinolamine dehydratase
MIM_RS05415	COG3186	Phenylalanine-4-hydroxylase
MIM_RS05430	COG2391	methyltransferase activity
MIM_RS05505	COG0629	single-stranded DNA binding
MIM_RS05635	COG0305	Participates in initiation and elongation during chromosome replication
MIM_RS05645	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
MIM_RS05700	COG1802	Transcriptional regulator
MIM_RS05700	COG4626	Terminase
MIM_RS05710	COG0740	serine-type endopeptidase activity
MIM_RS05720	COG3344	reverse transcriptase
MIM_RS05775	COG3344	reverse transcriptase
MIM_RS05880	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS05890	COG2010	Cytochrome c
MIM_RS05905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIM_RS05905	COG2169	Transcriptional regulator
MIM_RS05910	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS05915	COG0583	DNA-binding transcription factor activity
MIM_RS05950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_RS05960	COG0531	amino acid
MIM_RS05965	COG1408	metallophosphoesterase
MIM_RS05990	COG3842	ATPase activity
MIM_RS05995	COG0546	phosphoglycolate phosphatase activity
MIM_RS06015	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
MIM_RS06025	COG3346	SURF1 family
MIM_RS06030	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
MIM_RS06035	COG1845	cytochrome c oxidase, subunit III
MIM_RS06040	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
MIM_RS06045	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
MIM_RS06050	COG0477	Major facilitator Superfamily
MIM_RS06085	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIM_RS06090	COG0735	belongs to the Fur family
MIM_RS06095	COG0497	DNA recombination
MIM_RS06100	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MIM_RS06105	COG1420	regulation of RNA biosynthetic process
MIM_RS06110	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
MIM_RS06115	COG3217	Mosc domain protein beta barrel domain protein
MIM_RS06115	COG0633	Ferredoxin
MIM_RS06120	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MIM_RS06125	COG0443	Heat shock 70 kDa protein
MIM_RS06130	COG0484	heat shock protein binding
MIM_RS06140	COG0725	ABC transporter, periplasmic molybdate-binding protein
MIM_RS06145	COG4149	molybdate abc transporter
MIM_RS06150	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
MIM_RS06155	COG2005	Transcriptional regulator
MIM_RS06155	COG3585	molybdate ion transport
MIM_RS06165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIM_RS06200	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS06205	COG0583	DNA-binding transcription factor activity
MIM_RS06210	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS06220	COG3976	FMN-binding domain protein
MIM_RS06220	COG0431	NADPH-dependent FMN reductase
MIM_RS06220	COG1053	succinate dehydrogenase
MIM_RS06230	COG1054	Belongs to the UPF0176 family
MIM_RS06245	COG0492	ferredoxin-NADP+ reductase activity
MIM_RS06250	COG1674	ftsk spoiiie
MIM_RS06255	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MIM_RS06260	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MIM_RS06270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MIM_RS06275	COG3022	response to hydroperoxide
MIM_RS06280	COG2271	Major facilitator Superfamily
MIM_RS06285	COG1289	transmembrane transporter activity
MIM_RS06290	COG0028	Belongs to the TPP enzyme family
MIM_RS06295	COG0440	acetolactate synthase activity
MIM_RS06300	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
MIM_RS06310	COG0436	Aminotransferase
MIM_RS06345	COG1960	acyl-CoA dehydrogenase activity
MIM_RS06350	COG1024	Enoyl-CoA hydratase
MIM_RS06365	COG2050	protein possibly involved in aromatic compounds catabolism
MIM_RS06370	COG1960	acyl-CoA dehydrogenase activity
MIM_RS06375	COG1960	acyl-CoA dehydrogenase activity
MIM_RS06385	COG0183	Belongs to the thiolase family
MIM_RS06390	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS06400	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_RS06410	COG1126	abc transporter atp-binding protein
MIM_RS06415	COG0765	amino acid transport
MIM_RS06420	COG0765	amino acid transport
MIM_RS06430	COG0688	phosphatidylethanolamine metabolic process
MIM_RS06435	COG1183	phosphatidylcholine synthase activity
MIM_RS06445	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MIM_RS06450	COG1185	polyribonucleotide nucleotidyltransferase activity
MIM_RS06455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIM_RS06460	COG3193	protein, possibly involved in utilization of glycolate and propanediol
MIM_RS06480	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIM_RS06495	COG0009	L-threonylcarbamoyladenylate synthase
MIM_RS06500	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_RS06505	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
MIM_RS06510	COG2850	peptidyl-arginine hydroxylation
MIM_RS06515	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MIM_RS06520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS06525	COG0765	amino acid transport
MIM_RS06530	COG0765	amino acid transport
MIM_RS06535	COG1126	abc transporter atp-binding protein
MIM_RS06540	COG1335	isochorismatase
MIM_RS06545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_RS06550	COG0679	Auxin Efflux Carrier
MIM_RS06555	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MIM_RS06560	COG0668	transmembrane transport
MIM_RS06570	COG0483	inositol monophosphate 1-phosphatase activity
MIM_RS06575	COG1968	undecaprenyl-diphosphatase activity
MIM_RS06580	COG2030	dehydratase
MIM_RS06585	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS06590	COG0583	DNA-binding transcription factor activity
MIM_RS06610	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_RS06630	COG1024	Enoyl-CoA hydratase
MIM_RS06650	COG0215	cysteine-tRNA ligase activity
MIM_RS06660	COG0825	malonyl-CoA metabolic process
MIM_RS06695	COG0583	DNA-binding transcription factor activity
MIM_RS06705	COG2271	Major facilitator Superfamily
MIM_RS06710	COG1802	Transcriptional regulator
MIM_RS06730	COG1024	Enoyl-CoA hydratase
MIM_RS06765	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS06770	COG0583	DNA-binding transcription factor activity
MIM_RS06780	COG1737	Transcriptional regulator
MIM_RS06795	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS06800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS06805	COG1120	ATPase activity
MIM_RS06820	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
MIM_RS06885	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
MIM_RS06890	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MIM_RS06900	COG0527	aspartate kinase activity
MIM_RS06905	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_RS06915	COG1960	acyl-CoA dehydrogenase activity
MIM_RS06920	COG0598	Magnesium transport protein CorA
MIM_RS06935	COG1666	GTP binding
MIM_RS06940	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MIM_RS06960	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
MIM_RS06965	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_RS07005	COG0039	L-malate dehydrogenase activity
MIM_RS07020	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
MIM_RS07025	COG1053	succinate dehydrogenase
MIM_RS07030	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
MIM_RS07035	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
MIM_RS07040	COG0372	Belongs to the citrate synthase family
MIM_RS07045	COG1846	Transcriptional regulator
MIM_RS07065	COG0567	Dehydrogenase, E1 component
MIM_RS07070	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIM_RS07075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIM_RS07080	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
MIM_RS07090	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
MIM_RS07095	COG0747	negative chemotaxis
MIM_RS07100	COG0601	transmembrane transport
MIM_RS07105	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS07110	COG0444	Belongs to the ABC transporter superfamily
MIM_RS07115	COG4608	Belongs to the ABC transporter superfamily
MIM_RS07120	COG5265	(ABC) transporter
MIM_RS07125	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS07140	COG2183	response to ionizing radiation
MIM_RS07145	COG1199	ATP-dependent helicase activity
MIM_RS07155	COG0564	pseudouridine synthase activity
MIM_RS07160	COG1496	oxidoreductase activity
MIM_RS07165	COG3243	poly(R)-hydroxyalkanoic acid synthase
MIM_RS07170	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS07175	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
MIM_RS07190	COG3237	CsbD-like
MIM_RS07225	COG0720	synthase
MIM_RS07230	COG0602	queuosine metabolic process
MIM_RS07235	COG0667	Aldo Keto reductase
MIM_RS07265	COG0702	epimerase
MIM_RS07280	COG0656	L-ascorbic acid biosynthetic process
MIM_RS07285	COG2814	Major facilitator Superfamily
MIM_RS07295	COG1960	acyl-CoA dehydrogenase activity
MIM_RS07300	COG0583	DNA-binding transcription factor activity
MIM_RS07305	COG0427	acetyl-CoA hydrolase
MIM_RS07310	COG1024	Enoyl-CoA hydratase
MIM_RS07315	COG1960	acyl-CoA dehydrogenase activity
MIM_RS07345	COG3386	PFAM SMP-30 Gluconolaconase
MIM_RS07380	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS07385	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS07390	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS07400	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS07405	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS07430	COG3093	addiction module antidote protein HigA
MIM_RS07440	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MIM_RS07445	COG1187	pseudouridine synthase activity
MIM_RS07450	COG0779	Required for maturation of 30S ribosomal subunits
MIM_RS07455	COG0195	Participates in both transcription termination and antitermination
MIM_RS07455	COG2251	uridine kinase activity
MIM_RS07465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MIM_RS07470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
MIM_RS07475	COG1217	gtp-binding protein TYPA
MIM_RS07485	COG2326	polyphosphate kinase activity
MIM_RS07490	COG1620	l-lactate permease
MIM_RS07495	COG3842	ATPase activity
MIM_RS07500	COG0395	ABC-type sugar transport system, permease component
MIM_RS07505	COG1175	transmembrane transport
MIM_RS07520	COG0456	acetyltransferase
MIM_RS07525	COG0385	Bile acid
MIM_RS07530	COG3284	Transcriptional regulator
MIM_RS07535	COG0535	radical SAM domain protein
MIM_RS07545	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
MIM_RS07550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MIM_RS07560	COG3791	Glutathione-dependent formaldehyde-activating
MIM_RS07565	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MIM_RS07570	COG0191	fructose-bisphosphate aldolase activity
MIM_RS07575	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIM_RS07580	COG3954	Phosphoribulokinase
MIM_RS07585	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MIM_RS07590	COG0464	growth
MIM_RS07600	COG1850	ribulose-bisphosphate carboxylase activity
MIM_RS07660	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIM_RS07675	COG0662	Cupin 2, conserved barrel domain protein
MIM_RS07680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MIM_RS07685	COG0504	CTP synthase activity
MIM_RS07690	COG2877	3-deoxy-8-phosphooctulonate synthase activity
MIM_RS07695	COG0477	Major facilitator Superfamily
MIM_RS07700	COG0148	phosphopyruvate hydratase activity
MIM_RS07705	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
MIM_RS07715	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MIM_RS07725	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MIM_RS07740	COG1981	membrane
MIM_RS07745	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
MIM_RS07760	COG0495	leucyl-tRNA aminoacylation
MIM_RS07765	COG2197	response regulator
MIM_RS07780	COG1611	Belongs to the LOG family
MIM_RS07785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIM_RS07785	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MIM_RS07790	COG1280	lysine exporter protein (LysE YggA)
MIM_RS07795	COG0501	Belongs to the peptidase M48B family
MIM_RS07810	COG1722	exodeoxyribonuclease VII activity
MIM_RS07815	COG0142	geranyltranstransferase activity
MIM_RS07825	COG1469	GTP cyclohydrolase I activity
MIM_RS07830	COG0360	Binds together with S18 to 16S ribosomal RNA
MIM_RS07835	COG2965	DNA replication, synthesis of RNA primer
MIM_RS07840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
MIM_RS07850	COG0305	Participates in initiation and elongation during chromosome replication
MIM_RS07860	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
MIM_RS07865	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MIM_RS07875	COG0436	Aminotransferase
MIM_RS07915	COG1562	ergosterol biosynthetic process
MIM_RS07920	COG1562	ergosterol biosynthetic process
MIM_RS07925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MIM_RS07930	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS07945	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
MIM_RS07950	COG2346	COG2346, Truncated hemoglobins
MIM_RS07955	COG3642	lipopolysaccharide core region biosynthetic process
MIM_RS07960	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
MIM_RS07965	COG3842	ATPase activity
MIM_RS07970	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_RS07975	COG1177	transmembrane transport
MIM_RS07985	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MIM_RS07995	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
MIM_RS08000	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
MIM_RS08000	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
MIM_RS08005	COG1643	Atp-dependent helicase
MIM_RS08015	COG0438	transferase activity, transferring glycosyl groups
MIM_RS08020	COG0726	polysaccharide deacetylase
MIM_RS08025	COG1335	isochorismatase
MIM_RS08030	COG1733	regulation of RNA biosynthetic process
MIM_RS08045	COG1132	(ABC) transporter
MIM_RS08055	COG1530	ribonuclease E activity
MIM_RS08065	COG4771	TonB-dependent receptor
MIM_RS08105	COG3258	Cytochrome c
MIM_RS08140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS08145	COG2833	Protein of unknown function (DUF455)
MIM_RS08150	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_RS08160	COG0175	sulfate reduction
MIM_RS08165	COG0175	sulfate reduction
MIM_RS08170	COG2895	sulfate adenylyltransferase (ATP) activity
MIM_RS08175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
MIM_RS08180	COG4208	sulfate ABC transporter
MIM_RS08185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MIM_RS08190	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
MIM_RS08195	COG1253	flavin adenine dinucleotide binding
MIM_RS08200	COG4178	(ABC) transporter
MIM_RS08215	COG0730	response to heat
MIM_RS08220	COG0557	exoribonuclease II activity
MIM_RS08225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIM_RS08245	COG3344	reverse transcriptase
MIM_RS08250	COG2354	Protein conserved in bacteria
MIM_RS08275	COG0420	3'-5' exonuclease activity
MIM_RS08280	COG0419	ATPase involved in DNA repair
MIM_RS08290	COG0642	Histidine kinase
MIM_RS08295	COG3158	transport of potassium into the cell
MIM_RS08300	COG0137	argininosuccinate synthase activity
MIM_RS08305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
MIM_RS08315	COG0268	Binds directly to 16S ribosomal RNA
MIM_RS08320	COG0728	peptidoglycan biosynthetic process
MIM_RS08330	COG0563	adenylate kinase activity
MIM_RS08335	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
MIM_RS08340	COG2835	tetraacyldisaccharide 4'-kinase activity
MIM_RS08345	COG1663	tetraacyldisaccharide 4'-kinase activity
MIM_RS08355	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIM_RS08370	COG1278	Cold shock
MIM_RS08375	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
MIM_RS08380	COG0542	response to heat
MIM_RS08385	COG2995	paraquat-inducible protein a
MIM_RS08390	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
MIM_RS08390	COG3008	intermembrane lipid transfer
MIM_RS08410	COG0756	dUTP diphosphatase activity
MIM_RS08420	COG0586	Pfam SNARE associated Golgi protein
MIM_RS08425	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MIM_RS08430	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MIM_RS08435	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MIM_RS08440	COG0196	riboflavin kinase activity
MIM_RS08445	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MIM_RS08450	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIM_RS08450	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MIM_RS08460	COG0210	DNA helicase
MIM_RS08505	COG1671	Belongs to the UPF0178 family
MIM_RS08510	COG2070	2-Nitropropane dioxygenase
MIM_RS08535	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MIM_RS08560	COG3618	amidohydrolase
MIM_RS08590	COG4964	Belongs to the GSP D family
MIM_RS08620	COG0583	DNA-binding transcription factor activity
MIM_RS08625	COG1960	acyl-CoA dehydrogenase activity
MIM_RS08635	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS08640	COG1960	acyl-CoA dehydrogenase activity
MIM_RS08645	COG0450	alkyl hydroperoxide reductase
MIM_RS08660	COG0335	large ribosomal subunit rRNA binding
MIM_RS08665	COG0494	nUDIX hydrolase
MIM_RS08670	COG1162	GTPase activity
MIM_RS08675	COG0501	Belongs to the peptidase M48B family
MIM_RS08680	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
MIM_RS08685	COG0736	holo-[acyl-carrier-protein] synthase activity
MIM_RS08690	COG1472	Belongs to the glycosyl hydrolase 3 family
MIM_RS08695	COG0322	excinuclease ABC activity
MIM_RS08700	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
MIM_RS08710	COG2224	Isocitrate lyase
MIM_RS08725	COG2086	electron transfer activity
MIM_RS08735	COG0501	Belongs to the peptidase M48B family
MIM_RS08745	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
MIM_RS08750	COG0038	chloride channel
MIM_RS08755	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MIM_RS08770	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIM_RS08795	COG1295	ribonuclease BN
MIM_RS08805	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
MIM_RS08810	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
MIM_RS08825	COG0066	3-isopropylmalate dehydratase activity
MIM_RS08835	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MIM_RS08845	COG0101	tRNA pseudouridine synthase activity
MIM_RS08850	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_RS08860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_RS08865	COG0135	phosphoribosylanthranilate isomerase activity
MIM_RS08870	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS08875	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_RS08895	COG0488	(ABC) transporter
MIM_RS08900	COG2890	protein-(glutamine-N5) methyltransferase activity
MIM_RS08910	COG2171	N-acyltransferase activity
MIM_RS08915	COG0436	Aminotransferase
MIM_RS08930	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS08940	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS08950	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_RS08955	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_RS08960	COG0165	Argininosuccinate lyase
MIM_RS08970	COG1285	pathogenesis
MIM_RS08975	COG0697	spore germination
MIM_RS08980	COG0477	Major facilitator Superfamily
MIM_RS08990	COG0583	DNA-binding transcription factor activity
MIM_RS08995	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS09000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_RS09020	COG2814	Major facilitator Superfamily
MIM_RS09025	COG0625	glutathione transferase activity
MIM_RS09030	COG0737	Belongs to the 5'-nucleotidase family
MIM_RS09035	COG2130	NADP-dependent
MIM_RS09040	COG0583	DNA-binding transcription factor activity
MIM_RS09050	COG0625	glutathione transferase activity
MIM_RS09060	COG3153	acetyltransferase
MIM_RS09070	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_RS09075	COG2205	protein histidine kinase activity
MIM_RS09080	COG0745	RESPONSE REGULATOR receiver
MIM_RS09095	COG3328	transposase activity
MIM_RS09115	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MIM_RS09125	COG2814	Major facilitator Superfamily
MIM_RS09150	COG1522	sequence-specific DNA binding
MIM_RS09165	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS09170	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS09185	COG0583	DNA-binding transcription factor activity
MIM_RS09205	COG0765	amino acid transport
MIM_RS09210	COG0765	amino acid transport
MIM_RS09215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_RS09225	COG0277	FAD linked oxidase domain protein
MIM_RS09235	COG1846	Transcriptional regulator
MIM_RS09250	COG3971	2-oxopent-4-enoate hydratase activity
MIM_RS09260	COG3384	dioxygenase
MIM_RS09265	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS09270	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS09275	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS09285	COG0179	Fumarylacetoacetate (FAA) hydrolase
MIM_RS09290	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS09300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIM_RS09305	COG0028	Belongs to the TPP enzyme family
MIM_RS09315	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS09320	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS09330	COG0543	2 iron, 2 sulfur cluster binding
MIM_RS09330	COG0633	Ferredoxin
MIM_RS09335	COG4638	Rieske (2fe-2S)
MIM_RS09340	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS09360	COG0583	DNA-binding transcription factor activity
MIM_RS09370	COG0456	acetyltransferase
MIM_RS09380	COG0662	Cupin 2, conserved barrel domain protein
MIM_RS09385	COG5285	phytanoyl-CoA dioxygenase
MIM_RS09400	COG0656	L-ascorbic acid biosynthetic process
MIM_RS09410	COG0525	valine-tRNA ligase activity
MIM_RS09415	COG0105	UTP biosynthetic process
MIM_RS09420	COG0820	rRNA (adenine-C2-)-methyltransferase activity
MIM_RS09435	COG0124	histidyl-tRNA synthetase
MIM_RS09445	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MIM_RS09450	COG1160	GTP binding
MIM_RS09460	COG1923	regulation of RNA biosynthetic process
MIM_RS09465	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MIM_RS09470	COG0330	HflC and HflK could
MIM_RS09475	COG0330	HflC and HflK could
MIM_RS09480	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
MIM_RS09485	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MIM_RS09495	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MIM_RS09530	COG0454	-acetyltransferase
MIM_RS09545	COG3042	response to heat
MIM_RS09550	COG2841	Protein conserved in bacteria
MIM_RS09555	COG0628	permease
MIM_RS09565	COG3135	benzoate transporter
MIM_RS09570	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MIM_RS09580	COG0556	nucleotide-excision repair
MIM_RS09595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MIM_RS09600	COG2137	regulation of response to DNA damage stimulus
MIM_RS09605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MIM_RS09610	COG0583	DNA-binding transcription factor activity
MIM_RS09625	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_RS09630	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
MIM_RS09635	COG0861	Integral membrane protein TerC family
MIM_RS09640	COG0861	Integral membrane protein TerC family
MIM_RS09645	COG0181	hydroxymethylbilane synthase activity
MIM_RS09665	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
MIM_RS09685	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
MIM_RS09710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIM_RS09715	COG0425	Belongs to the sulfur carrier protein TusA family
MIM_RS09720	COG0228	four-way junction DNA binding
MIM_RS09725	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MIM_RS09730	COG0336	Belongs to the RNA methyltransferase TrmD family
MIM_RS09735	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS09740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MIM_RS09750	COG1104	cysteine desulfurase activity
MIM_RS09755	COG0822	iron-sulfur transferase activity
MIM_RS09760	COG0316	Belongs to the HesB IscA family
MIM_RS09765	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
MIM_RS09770	COG0443	Heat shock 70 kDa protein
MIM_RS09775	COG0633	Ferredoxin
MIM_RS09790	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MIM_RS09820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MIM_RS09825	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS09830	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
MIM_RS09835	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MIM_RS09870	COG1136	(ABC) transporter
MIM_RS09875	COG0084	hydrolase, TatD family'
MIM_RS09880	COG2333	competence protein COMEC
MIM_RS09880	COG0658	competence protein
MIM_RS09890	COG0613	PHP domain protein
MIM_RS09900	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
MIM_RS09905	COG0584	glycerophosphoryl diester phosphodiesterase
MIM_RS09910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIM_RS09920	COG4181	ATPase activity
MIM_RS09925	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIM_RS09930	COG1758	RNA polymerase activity
MIM_RS09935	COG0194	GDP metabolic process
MIM_RS09940	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS09950	COG1561	YicC-like family, N-terminal region
MIM_RS09955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
MIM_RS09960	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MIM_RS09965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
MIM_RS09970	COG0174	glutamine synthetase
MIM_RS09975	COG3852	Histidine kinase
MIM_RS09985	COG3842	ATPase activity
MIM_RS09990	COG1178	ABC-type Fe3 transport system permease component
MIM_RS09995	COG1840	ABC-type Fe3 transport system, periplasmic component
MIM_RS10020	COG3842	ATPase activity
MIM_RS10025	COG0395	ABC-type sugar transport system, permease component
MIM_RS10030	COG1175	transmembrane transport
MIM_RS10045	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
MIM_RS10075	COG1999	signal sequence binding
MIM_RS10080	COG0339	signal peptide processing
MIM_RS10085	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MIM_RS10090	COG4566	intracellular signal transduction
MIM_RS10105	COG0508	dehydrogenase complex catalyzes the overall conversion of
MIM_RS10110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MIM_RS10115	COG0285	dihydrofolate synthase activity
MIM_RS10125	COG1286	toxin biosynthetic process
MIM_RS10140	COG2814	Major facilitator Superfamily
MIM_RS10155	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
MIM_RS10165	COG0052	Belongs to the universal ribosomal protein uS2 family
MIM_RS10170	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MIM_RS10175	COG0528	UMP kinase activity
MIM_RS10180	COG0233	cytoplasmic translational termination
MIM_RS10185	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MIM_RS10195	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
MIM_RS10200	COG0750	zinc metalloprotease
MIM_RS10215	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIM_RS10220	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIM_RS10225	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIM_RS10230	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
MIM_RS10235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
MIM_RS10245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MIM_RS10275	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
MIM_RS10280	COG2867	negative regulation of translational initiation
MIM_RS10285	COG2914	Belongs to the UPF0125 (RnfH) family
MIM_RS10290	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS10290	COG1024	Enoyl-CoA hydratase
MIM_RS10295	COG0354	folic acid binding
MIM_RS10300	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MIM_RS10305	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MIM_RS10315	COG0084	hydrolase, TatD family'
MIM_RS10330	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
MIM_RS10335	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MIM_RS10340	COG0625	glutathione transferase activity
MIM_RS10345	COG0386	Belongs to the glutathione peroxidase family
MIM_RS10350	COG5006	permease, DMT superfamily
MIM_RS10355	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS10360	COG0697	spore germination
MIM_RS10370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS10410	COG0765	amino acid transport
MIM_RS10420	COG1609	Transcriptional regulator
MIM_RS10425	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MIM_RS10460	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS10465	COG0583	DNA-binding transcription factor activity
MIM_RS10470	COG0583	DNA-binding transcription factor activity
MIM_RS10480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS10490	COG3386	PFAM SMP-30 Gluconolaconase
MIM_RS10495	COG0583	DNA-binding transcription factor activity
MIM_RS10500	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS10515	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_RS10525	COG0154	amidase activity
MIM_RS10530	COG2186	Transcriptional regulator
MIM_RS10535	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_RS10560	COG0583	DNA-binding transcription factor activity
MIM_RS10575	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS10575	COG2030	dehydratase
MIM_RS10595	COG1960	acyl-CoA dehydrogenase activity
MIM_RS10655	COG0683	leucine binding
MIM_RS10665	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS10670	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MIM_RS10675	COG0583	DNA-binding transcription factor activity
MIM_RS10720	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS10740	COG4221	oxidoreductase activity
MIM_RS10760	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MIM_RS10765	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS10770	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS10785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_RS10790	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS10835	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS10840	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS10845	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS10855	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS10860	COG1024	Enoyl-CoA hydratase
MIM_RS10865	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS10870	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS10875	COG2204	response regulator
MIM_RS10915	COG0300	oxidoreductase activity
MIM_RS10945	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS10950	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS10960	COG1024	Enoyl-CoA hydratase
MIM_RS10965	COG1960	acyl-CoA dehydrogenase activity
MIM_RS10970	COG1024	Enoyl-CoA hydratase
MIM_RS10995	COG0583	DNA-binding transcription factor activity
MIM_RS11000	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS11005	COG1960	acyl-CoA dehydrogenase activity
MIM_RS11015	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
MIM_RS11030	COG0519	Catalyzes the synthesis of GMP from XMP
MIM_RS11030	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MIM_RS11045	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIM_RS11055	COG1764	response to oxidative stress
MIM_RS11060	COG0656	L-ascorbic acid biosynthetic process
MIM_RS11065	COG0583	DNA-binding transcription factor activity
MIM_RS11070	COG0739	heme binding
MIM_RS11090	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS11100	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
MIM_RS11100	COG2111	Na H antiporter
MIM_RS11105	COG1006	Multisubunit Na H antiporter MnhC subunit
MIM_RS11110	COG0651	ATP synthesis coupled electron transport
MIM_RS11120	COG2212	antiporter activity
MIM_RS11130	COG0778	Nitroreductase
MIM_RS11135	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
MIM_RS11145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
MIM_RS11160	COG4120	Belongs to the binding-protein-dependent transport system permease family
MIM_RS11175	COG0183	Belongs to the thiolase family
MIM_RS11190	COG1187	pseudouridine synthase activity
MIM_RS11195	COG3161	chorismate lyase activity
MIM_RS11200	COG0347	Belongs to the P(II) protein family
MIM_RS11205	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIM_RS11205	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
MIM_RS11210	COG0165	Argininosuccinate lyase
MIM_RS11215	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MIM_RS11230	COG4942	peptidase
MIM_RS11240	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
MIM_RS11245	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
MIM_RS11250	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MIM_RS11255	COG2252	PERMEase
MIM_RS11260	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIM_RS11270	COG0488	(ABC) transporter
MIM_RS11275	COG1619	proteins homologs of microcin C7 resistance protein MccF
MIM_RS11280	COG0590	tRNA wobble adenosine to inosine editing
MIM_RS11290	COG3712	iron ion homeostasis
MIM_RS11295	COG1595	DNA-templated transcription, initiation
MIM_RS11315	COG2824	Alkylphosphonate utilization operon protein PhnA
MIM_RS11335	COG4691	Plasmid stability protein
MIM_RS11345	COG0519	Catalyzes the synthesis of GMP from XMP
MIM_RS11345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MIM_RS11360	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MIM_RS11360	COG0047	phosphoribosylformylglycinamidine synthase activity
MIM_RS11365	COG1686	Belongs to the peptidase S11 family
MIM_RS11390	COG0210	DNA helicase
MIM_RS11405	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MIM_RS11460	COG0776	regulation of translation
MIM_RS11465	COG0072	phenylalanine-tRNA ligase activity
MIM_RS11465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIM_RS11470	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MIM_RS11475	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MIM_RS11480	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MIM_RS11510	COG0004	ammonium transporteR
MIM_RS11515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MIM_RS11520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
MIM_RS11535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MIM_RS11540	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MIM_RS11555	COG3344	reverse transcriptase
MIM_RS11565	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
MIM_RS11575	COG0740	serine-type endopeptidase activity
MIM_RS11580	COG0544	peptidyl-prolyl cis-trans isomerase activity
MIM_RS11615	COG0829	nickel cation binding
MIM_RS11620	COG0831	urea catabolic process
MIM_RS11630	COG0832	Belongs to the urease beta subunit family
MIM_RS11635	COG0804	urea catabolic process
MIM_RS11640	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
MIM_RS11650	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MIM_RS11660	COG1760	l-serine dehydratase
MIM_RS11670	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
MIM_RS11675	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
MIM_RS11695	COG1278	Cold shock
MIM_RS11700	COG0542	response to heat
MIM_RS11725	COG1126	abc transporter atp-binding protein
MIM_RS11730	COG0765	amino acid transport
MIM_RS11750	COG2721	sulfolactate sulfo-lyase activity
MIM_RS11775	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS11785	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_RS11790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_RS11800	COG3237	CsbD-like
MIM_RS11835	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MIM_RS11890	COG0411	ABC transporter
MIM_RS11900	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
MIM_RS11935	COG3278	Belongs to the heme-copper respiratory oxidase family
MIM_RS11960	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_RS11965	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
MIM_RS11970	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
MIM_RS11980	COG0776	regulation of translation
MIM_RS11990	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MIM_RS11995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
MIM_RS12000	COG0287	Prephenate dehydrogenase
MIM_RS12005	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
MIM_RS12010	COG1605	Chorismate mutase
MIM_RS12010	COG0077	Prephenate dehydratase
MIM_RS12030	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
MIM_RS12040	COG2885	chlorophyll binding
MIM_RS12055	COG1091	dTDP-4-dehydrorhamnose reductase activity
MIM_RS12070	COG0793	Belongs to the peptidase S41A family
MIM_RS12075	COG2951	lytic endotransglycosylase activity
MIM_RS12085	COG5002	protein histidine kinase activity
MIM_RS12090	COG0745	RESPONSE REGULATOR receiver
MIM_RS12105	COG2323	membrane
MIM_RS12110	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
MIM_RS12115	COG2732	(Barnase) inhibitor
MIM_RS12130	COG2134	cdp-diacylglycerol pyrophosphatase
MIM_RS12140	COG0069	glutamate synthase activity
MIM_RS12160	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
MIM_RS12165	COG3909	cytochrome
MIM_RS12175	COG0482	sulfurtransferase activity
MIM_RS12180	COG0247	lactate metabolic process
MIM_RS12185	COG0277	FAD linked oxidase domain protein
MIM_RS12190	COG0277	FAD linked oxidase domain protein
MIM_RS12195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
MIM_RS12200	COG0312	modulator of DNA gyrase
MIM_RS12210	COG0308	aminopeptidase N
MIM_RS12215	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
MIM_RS12220	COG0667	Aldo Keto reductase
MIM_RS12235	COG1846	Transcriptional regulator
MIM_RS12240	COG0433	COG0433 Predicted ATPase
MIM_RS12245	COG0217	transcriptional regulatory protein
MIM_RS12250	COG0151	Belongs to the GarS family
MIM_RS12255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MIM_RS12260	COG0799	negative regulation of ribosome biogenesis
MIM_RS12265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MIM_RS12270	COG0424	maF-like protein
MIM_RS12275	COG0625	glutathione transferase activity
MIM_RS12280	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
MIM_RS12285	COG1047	Peptidyl-prolyl cis-trans
MIM_RS12290	COG2003	Belongs to the UPF0758 family
MIM_RS12295	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MIM_RS12305	COG3483	tryptophan 2,3-dioxygenase activity
MIM_RS12330	COG2814	Major facilitator Superfamily
MIM_RS12340	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MIM_RS12355	COG0583	DNA-binding transcription factor activity
MIM_RS12375	COG2363	Small membrane protein
MIM_RS12410	COG0791	NLP P60 protein
MIM_RS12425	COG1960	acyl-CoA dehydrogenase activity
MIM_RS12430	COG0183	Belongs to the thiolase family
MIM_RS12435	COG1024	Enoyl-CoA hydratase
MIM_RS12435	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS12450	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS12455	COG0583	DNA-binding transcription factor activity
MIM_RS12465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
MIM_RS12495	COG1381	Involved in DNA repair and RecF pathway recombination
MIM_RS12500	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MIM_RS12505	COG0571	ribonuclease III activity
MIM_RS12510	COG0681	Belongs to the peptidase S26 family
MIM_RS12520	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MIM_RS12545	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIM_RS12550	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MIM_RS12565	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MIM_RS12575	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MIM_RS12585	COG0424	maF-like protein
MIM_RS12595	COG3023	N-Acetylmuramoyl-L-alanine amidase
MIM_RS12600	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
MIM_RS12605	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
MIM_RS12615	COG0564	pseudouridine synthase activity
MIM_RS12620	COG1530	ribonuclease E activity
MIM_RS12645	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MIM_RS12650	COG0159	tryptophan synthase activity
MIM_RS12655	COG0133	tryptophan synthase activity
MIM_RS12660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MIM_RS12670	COG0251	oxidation-reduction process
MIM_RS12675	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MIM_RS12680	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
MIM_RS12695	COG2878	Part of a membrane complex involved in electron transport
MIM_RS12700	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
MIM_RS12710	COG0411	ABC transporter
MIM_RS12725	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIM_RS12730	COG2917	probably involved in intracellular septation
MIM_RS12740	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIM_RS12745	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MIM_RS12755	COG1196	nuclear chromosome segregation
MIM_RS12765	COG0477	Major facilitator Superfamily
MIM_RS12775	COG1214	PFAM Peptidase M22, glycoprotease
MIM_RS12790	COG0450	alkyl hydroperoxide reductase
MIM_RS12795	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_RS12800	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
MIM_RS12805	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
MIM_RS12810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MIM_RS12815	COG0560	Phosphoserine phosphatase
MIM_RS12830	COG2176	DNA-directed DNA polymerase activity
MIM_RS12840	COG1007	ATP synthesis coupled electron transport
MIM_RS12855	COG0713	ATP synthesis coupled electron transport
MIM_RS12865	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_RS12870	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
MIM_RS12875	COG1034	ATP synthesis coupled electron transport
MIM_RS12885	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MIM_RS12890	COG0649	NAD binding
MIM_RS12895	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_RS12900	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_RS12905	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
MIM_RS12910	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
MIM_RS12915	COG3344	reverse transcriptase
MIM_RS12925	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
MIM_RS12935	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIM_RS12940	COG0149	triose-phosphate isomerase activity
MIM_RS12945	COG0604	alcohol dehydrogenase
MIM_RS12945	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS12945	COG3321	synthase
MIM_RS12950	COG0589	response to stress
MIM_RS12955	COG0659	secondary active sulfate transmembrane transporter activity
MIM_RS12960	COG2814	Major facilitator Superfamily
MIM_RS12995	COG1396	sequence-specific DNA binding
MIM_RS12995	COG3800	Transcriptional regulator
MIM_RS13000	COG2860	membrane
MIM_RS13010	COG0583	DNA-binding transcription factor activity
MIM_RS13025	COG1024	Enoyl-CoA hydratase
MIM_RS13040	COG3128	pkhd-type hydroxylase
MIM_RS13045	COG4774	siderophore transport
MIM_RS13060	COG0625	glutathione transferase activity
MIM_RS13065	COG0477	Major facilitator Superfamily
MIM_RS13080	COG1960	acyl-CoA dehydrogenase activity
MIM_RS13085	COG1024	Enoyl-CoA hydratase
MIM_RS13095	COG1024	Enoyl-CoA hydratase
MIM_RS13115	COG0183	Belongs to the thiolase family
MIM_RS13120	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS13120	COG1024	Enoyl-CoA hydratase
MIM_RS13165	COG4106	trans-aconitate 2-methyltransferase activity
MIM_RS13180	COG0438	transferase activity, transferring glycosyl groups
MIM_RS13205	COG0076	glutamate decarboxylase activity
MIM_RS13220	COG0583	DNA-binding transcription factor activity
MIM_RS13225	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS13245	COG0583	DNA-binding transcription factor activity
MIM_RS13250	COG1346	cytolysis
MIM_RS13260	COG0583	DNA-binding transcription factor activity
MIM_RS13265	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MIM_RS13290	COG3278	Belongs to the heme-copper respiratory oxidase family
MIM_RS13295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_RS13310	COG2186	Transcriptional regulator
MIM_RS13315	COG0477	Major facilitator Superfamily
MIM_RS13320	COG0252	asparaginase activity
MIM_RS13330	COG0596	Alpha beta hydrolase
MIM_RS13340	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS13350	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS13360	COG3718	enzyme involved in inositol metabolism
MIM_RS13365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIM_RS13375	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS13430	COG0671	phosphoesterase, PA-phosphatase related
MIM_RS13450	COG4773	Receptor
MIM_RS13455	COG0577	efflux transmembrane transporter activity
MIM_RS13455	COG1136	(ABC) transporter
MIM_RS13460	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
MIM_RS13525	COG1404	Belongs to the peptidase S8 family
MIM_RS13535	COG0583	DNA-binding transcription factor activity
MIM_RS13560	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MIM_RS13585	COG3486	L-lysine 6-monooxygenase (NADPH) activity
MIM_RS13590	COG4773	Receptor
MIM_RS13600	COG0789	Transcriptional regulator
MIM_RS13610	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MIM_RS13635	COG0248	Ppx GppA phosphatase
MIM_RS13645	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MIM_RS13655	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
MIM_RS13660	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
MIM_RS13665	COG1534	Rna-binding protein
MIM_RS13670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MIM_RS13675	COG2233	PERMEase
MIM_RS13680	COG0406	alpha-ribazole phosphatase activity
MIM_RS13685	COG0300	oxidoreductase activity
MIM_RS13695	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MIM_RS13700	COG0505	Belongs to the CarA family
MIM_RS13710	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
MIM_RS13715	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MIM_RS13720	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
MIM_RS13730	COG1074	ATP-dependent DNA helicase activity
MIM_RS13745	COG2188	Transcriptional regulator
MIM_RS13770	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIM_RS13775	COG3657	addiction module killer protein
MIM_RS13790	COG4974	Belongs to the 'phage' integrase family
MIM_RS13800	COG0802	atpase or kinase
MIM_RS13805	COG0860	N-Acetylmuramoyl-L-alanine amidase
MIM_RS13810	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MIM_RS13815	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
MIM_RS13820	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MIM_RS13825	COG0628	permease
MIM_RS13830	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIM_RS13840	COG0617	tRNA 3'-terminal CCA addition
MIM_RS13850	COG4608	Belongs to the ABC transporter superfamily
MIM_RS13855	COG0444	Belongs to the ABC transporter superfamily
MIM_RS13860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS13865	COG0601	transmembrane transport
MIM_RS13870	COG0747	negative chemotaxis
MIM_RS13875	COG0747	negative chemotaxis
MIM_RS13880	COG0747	negative chemotaxis
MIM_RS13890	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS13895	COG1414	Transcriptional regulator
MIM_RS13915	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_RS13920	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS13925	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS13930	COG1673	EVE domain
MIM_RS13960	COG1024	Enoyl-CoA hydratase
MIM_RS13965	COG0752	glycyl-tRNA synthetase alpha subunit
MIM_RS13970	COG0751	glycine-tRNA ligase activity
MIM_RS13975	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
MIM_RS13980	COG0204	Acyl-transferase
MIM_RS13990	COG0346	lactoylglutathione lyase activity
MIM_RS14000	COG1929	Belongs to the glycerate kinase type-1 family
MIM_RS14005	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MIM_RS14010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MIM_RS14025	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
MIM_RS14055	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIM_RS14060	COG0850	regulation of cytokinetic process
MIM_RS14065	COG2894	cell division
MIM_RS14070	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
MIM_RS14080	COG0488	(ABC) transporter
MIM_RS14090	COG1215	transferase activity, transferring glycosyl groups
MIM_RS14095	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MIM_RS14100	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MIM_RS14110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
MIM_RS14115	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
MIM_RS14120	COG0259	pyridoxamine-phosphate oxidase activity
MIM_RS14125	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_RS14130	COG0579	oxidoreductase
MIM_RS14140	COG3539	Fimbrial protein
MIM_RS14165	COG1960	acyl-CoA dehydrogenase activity
MIM_RS14175	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
MIM_RS14180	COG0829	nickel cation binding
MIM_RS14195	COG0832	Belongs to the urease beta subunit family
MIM_RS14200	COG0831	urea catabolic process
MIM_RS14205	COG2030	dehydratase
MIM_RS14225	COG0765	amino acid transport
MIM_RS14230	COG0765	amino acid transport
MIM_RS14235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS14240	COG0583	DNA-binding transcription factor activity
MIM_RS14265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MIM_RS14310	COG3246	L-lysine catabolic process to acetate
MIM_RS14315	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MIM_RS14325	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS14330	COG3108	Peptidase M15
MIM_RS14335	COG2989	Protein conserved in bacteria
MIM_RS14340	COG0412	Dienelactone hydrolase
MIM_RS14370	COG3836	Belongs to the HpcH HpaI aldolase family
MIM_RS14380	COG1380	Effector of murein hydrolase LrgA
MIM_RS14385	COG1346	cytolysis
MIM_RS14395	COG1490	D-aminoacyl-tRNA deacylase activity
MIM_RS14405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_RS14410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS14415	COG1126	abc transporter atp-binding protein
MIM_RS14420	COG0765	amino acid transport
MIM_RS14425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS14430	COG1396	sequence-specific DNA binding
MIM_RS14440	COG2267	carboxylic ester hydrolase activity
MIM_RS14455	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS14470	COG1021	2,3-dihydroxybenzoate-AMP ligase
MIM_RS14485	COG1309	transcriptional regulator
MIM_RS14495	COG1473	amidohydrolase
MIM_RS14500	COG1598	PFAM Uncharacterised protein family UPF0150
MIM_RS14520	COG0009	L-threonylcarbamoyladenylate synthase
MIM_RS14525	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MIM_RS14530	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MIM_RS14535	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MIM_RS14555	COG0521	Mo-molybdopterin cofactor biosynthetic process
MIM_RS14560	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
MIM_RS14565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MIM_RS14575	COG0126	phosphoglycerate kinase activity
MIM_RS14580	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
MIM_RS14585	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
MIM_RS14590	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MIM_RS14615	COG0436	Aminotransferase
MIM_RS14625	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
MIM_RS14645	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MIM_RS14655	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
MIM_RS14660	COG0343	queuine tRNA-ribosyltransferase activity
MIM_RS14665	COG1862	Preprotein translocase
MIM_RS14670	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIM_RS14675	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
MIM_RS14685	COG1702	phosphate starvation-inducible protein PhoH
MIM_RS14690	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MIM_RS14700	COG0815	Transfers the fatty acyl group on membrane lipoproteins
MIM_RS14705	COG0587	DNA-directed DNA polymerase activity
MIM_RS14740	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MIM_RS14745	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS14750	COG0583	DNA-binding transcription factor activity
MIM_RS14765	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS14775	COG3443	Belongs to the bacterial solute-binding protein 9 family
MIM_RS14835	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MIM_RS14840	COG2186	Transcriptional regulator
MIM_RS14845	COG2721	sulfolactate sulfo-lyase activity
MIM_RS14850	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MIM_RS14860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MIM_RS14865	COG0494	nUDIX hydrolase
MIM_RS14885	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS14890	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
MIM_RS14895	COG0697	spore germination
MIM_RS14910	COG0477	Major facilitator Superfamily
MIM_RS14915	COG0678	peroxiredoxin activity
MIM_RS14920	COG0315	cyclic pyranopterin monophosphate synthase activity
MIM_RS14935	COG0521	Mo-molybdopterin cofactor biosynthetic process
MIM_RS14940	COG0303	'Molybdopterin
MIM_RS14945	COG0746	molybdenum cofactor guanylyltransferase activity
MIM_RS14950	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
MIM_RS14960	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
MIM_RS14970	COG3383	formate dehydrogenase (NAD+) activity
MIM_RS14975	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
MIM_RS14985	COG2223	nitrite transmembrane transporter activity
MIM_RS15000	COG0589	response to stress
MIM_RS15020	COG0463	Glycosyl transferase, family 2
MIM_RS15025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
MIM_RS15035	COG0741	lytic transglycosylase activity
MIM_RS15035	COG1388	LysM domain
MIM_RS15040	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
MIM_RS15045	COG2226	methyltransferase
MIM_RS15050	COG0328	RNA-DNA hybrid ribonuclease activity
MIM_RS15075	COG5507	3-demethylubiquinone-9 3-methyltransferase
MIM_RS15135	COG0583	DNA-binding transcription factor activity
MIM_RS15140	COG0129	dihydroxy-acid dehydratase activity
MIM_RS15145	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS15155	COG1280	lysine exporter protein (LysE YggA)
MIM_RS15180	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
MIM_RS15180	COG0475	glutathione-regulated potassium exporter activity
MIM_RS15190	COG0252	asparaginase activity
MIM_RS15215	COG1999	signal sequence binding
MIM_RS15230	COG0243	molybdopterin cofactor binding
MIM_RS15235	COG2837	iron assimilation
MIM_RS15245	COG1132	(ABC) transporter
MIM_RS15250	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
MIM_RS15260	COG4977	sequence-specific DNA binding
MIM_RS15265	COG0523	cobalamin synthesis protein
MIM_RS15270	COG0735	belongs to the Fur family
MIM_RS15275	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
MIM_RS15310	COG0330	HflC and HflK could
MIM_RS15340	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MIM_RS15345	COG3657	addiction module killer protein
MIM_RS15360	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIM_RS15360	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
MIM_RS15365	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MIM_RS15370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MIM_RS15375	COG1881	PFAM PEBP family protein
MIM_RS15380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
MIM_RS15385	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
MIM_RS15390	COG0316	Belongs to the HesB IscA family
MIM_RS15400	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
MIM_RS15405	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MIM_RS15410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MIM_RS15420	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_RS15425	COG0312	modulator of DNA gyrase
MIM_RS15430	COG3028	Belongs to the UPF0307 family
MIM_RS15440	COG1042	CoA-binding domain protein
MIM_RS15440	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_RS15440	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_RS15445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MIM_RS15455	COG0762	integral membrane protein
MIM_RS15470	COG2264	protein methyltransferase activity
MIM_RS15475	COG0439	Biotin carboxylase
MIM_RS15480	COG0511	ligase activity, forming carbon-carbon bonds
MIM_RS15485	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
MIM_RS15490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MIM_RS15495	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MIM_RS15500	COG3150	esterase
MIM_RS15505	COG0557	exoribonuclease II activity
MIM_RS15510	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
MIM_RS15515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MIM_RS15525	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_RS15540	COG0540	Belongs to the ATCase OTCase family
MIM_RS15545	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MIM_RS15555	COG1678	Uncharacterized ACR, COG1678
MIM_RS15560	COG1773	rubredoxin
MIM_RS15565	COG0351	phosphomethylpyrimidine kinase
MIM_RS15570	COG0352	thiamine-phosphate diphosphorylase activity
MIM_RS15575	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
MIM_RS15580	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
MIM_RS15590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MIM_RS15595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MIM_RS15600	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MIM_RS15605	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
MIM_RS15615	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIM_RS15620	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
MIM_RS15625	COG1648	precorrin-2 dehydrogenase activity
MIM_RS15625	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
MIM_RS15630	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
MIM_RS15640	COG1858	cytochrome C peroxidase
MIM_RS15675	COG0437	4 iron, 4 sulfur cluster binding
MIM_RS15680	COG0348	domain, Protein
MIM_RS15700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
MIM_RS15730	COG2084	Dehydrogenase
MIM_RS15735	COG0494	nUDIX hydrolase
MIM_RS15740	COG0442	prolyl-tRNA aminoacylation
MIM_RS15745	COG0824	Thioesterase
MIM_RS15755	COG0848	biopolymer transport protein
MIM_RS15765	COG0823	Involved in the tonB-independent uptake of proteins
MIM_RS15785	COG0038	chloride channel
MIM_RS15805	COG0586	Pfam SNARE associated Golgi protein
MIM_RS15810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS15815	COG1120	ATPase activity
MIM_RS15825	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS15830	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
MIM_RS15830	COG0512	Glutamine amidotransferase of anthranilate synthase
MIM_RS15840	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
MIM_RS15845	COG1294	oxidase, subunit
MIM_RS15850	COG1271	oxidase subunit
MIM_RS15860	COG0583	DNA-binding transcription factor activity
MIM_RS15865	COG2814	Major facilitator Superfamily
MIM_RS15885	COG0235	Class ii aldolase
MIM_RS15905	COG0778	Nitroreductase
MIM_RS15905	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
MIM_RS15910	COG1846	Transcriptional regulator
MIM_RS15925	COG1566	PFAM secretion protein HlyD family protein
MIM_RS15950	COG2873	o-acetylhomoserine
MIM_RS15985	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MIM_RS15985	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIM_RS16000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS16005	COG0765	amino acid transport
MIM_RS16010	COG0765	amino acid transport
MIM_RS16015	COG0165	Argininosuccinate lyase
MIM_RS16025	COG1126	abc transporter atp-binding protein
MIM_RS16045	COG0477	Major facilitator Superfamily
MIM_RS16055	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
MIM_RS16065	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS16070	COG0601	transmembrane transport
MIM_RS16075	COG0747	negative chemotaxis
MIM_RS16080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS16085	COG0028	Belongs to the TPP enzyme family
MIM_RS16100	COG4176	ABC-type proline glycine betaine transport system permease component
MIM_RS16105	COG4175	Glycine betaine
MIM_RS16125	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
MIM_RS16130	COG1802	Transcriptional regulator
MIM_RS16135	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS16140	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_RS16145	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS16155	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS16165	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS16170	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS16175	COG1013	pyruvate-flavodoxin oxidoreductase activity
MIM_RS16185	COG0583	DNA-binding transcription factor activity
MIM_RS16190	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MIM_RS16195	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS16200	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
MIM_RS16205	COG1120	ATPase activity
MIM_RS16225	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS16255	COG0288	reversible hydration of carbon dioxide
MIM_RS16260	COG0861	Integral membrane protein TerC family
MIM_RS16270	COG0019	diaminopimelate decarboxylase activity
MIM_RS16325	COG1335	isochorismatase
MIM_RS16330	COG2309	aminopeptidase activity
MIM_RS16335	COG0596	Alpha beta hydrolase
MIM_RS16340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_RS16340	COG2010	Cytochrome c
MIM_RS16345	COG2080	2 iron, 2 sulfur cluster binding
MIM_RS16350	COG1529	Aldehyde oxidase and xanthine dehydrogenase
MIM_RS16350	COG2010	Cytochrome c
MIM_RS16355	COG1846	Transcriptional regulator
MIM_RS16360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_RS16365	COG2271	Major facilitator Superfamily
MIM_RS16380	COG1064	alcohol dehydrogenase
MIM_RS16395	COG2207	Transcriptional regulator
MIM_RS16400	COG0129	dihydroxy-acid dehydratase activity
MIM_RS16405	COG2076	Multidrug Resistance protein
MIM_RS16415	COG4944	Protein of unknown function (DUF1109)
MIM_RS16420	COG1595	DNA-templated transcription, initiation
MIM_RS16440	COG3220	belongs to the UPF0276 family
MIM_RS16470	COG1396	sequence-specific DNA binding
MIM_RS16470	COG3800	Transcriptional regulator
MIM_RS16480	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS16510	COG0730	response to heat
MIM_RS16515	COG0405	Gamma-glutamyltransferase
MIM_RS16530	COG1522	sequence-specific DNA binding
MIM_RS16545	COG2879	small protein
MIM_RS16550	COG1966	Carbon starvation protein
MIM_RS16560	COG2132	Multicopper oxidase
MIM_RS16580	COG1090	epimerase
MIM_RS16585	COG1733	regulation of RNA biosynthetic process
MIM_RS16590	COG3485	protocatechuate 3,4-dioxygenase
MIM_RS16595	COG0252	asparaginase activity
MIM_RS16610	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
MIM_RS16640	COG2814	Major facilitator Superfamily
MIM_RS16660	COG0543	2 iron, 2 sulfur cluster binding
MIM_RS16665	COG3258	Cytochrome c
MIM_RS16670	COG2863	cytochrome
MIM_RS16690	COG1902	pentaerythritol trinitrate reductase activity
MIM_RS16695	COG1335	isochorismatase
MIM_RS16715	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS16720	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS16725	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS16745	COG0583	DNA-binding transcription factor activity
MIM_RS16750	COG0252	asparaginase activity
MIM_RS16775	COG0657	acetylesterase activity
MIM_RS16785	COG1278	Cold shock
MIM_RS16855	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MIM_RS16890	COG0284	orotidine-5'-phosphate decarboxylase activity
MIM_RS16895	COG4691	Plasmid stability protein
MIM_RS16905	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
MIM_RS16910	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
MIM_RS16915	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MIM_RS16920	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
MIM_RS16940	COG1960	acyl-CoA dehydrogenase activity
MIM_RS16945	COG1024	Enoyl-CoA hydratase
MIM_RS16950	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS16980	COG0742	ribosomal rna small subunit methyltransferase
MIM_RS16985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MIM_RS16990	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
MIM_RS17030	COG4783	chaperone-mediated protein folding
MIM_RS17040	COG0848	biopolymer transport protein
MIM_RS17055	COG1629	transport
MIM_RS17055	COG4206	TonB-dependent receptor
MIM_RS17060	COG1770	oligopeptidase
MIM_RS17080	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
MIM_RS17085	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MIM_RS17095	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MIM_RS17100	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
MIM_RS17110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MIM_RS17115	COG0277	FAD linked oxidase domain protein
MIM_RS17125	COG0438	transferase activity, transferring glycosyl groups
MIM_RS17130	COG0438	transferase activity, transferring glycosyl groups
MIM_RS17135	COG0438	transferase activity, transferring glycosyl groups
MIM_RS17140	COG0367	asparagine synthase
MIM_RS17160	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MIM_RS17165	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MIM_RS17170	COG3344	reverse transcriptase
MIM_RS17180	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
MIM_RS17185	COG1765	OsmC-like protein
MIM_RS17190	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MIM_RS17205	COG0411	ABC transporter
MIM_RS17230	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
MIM_RS17255	COG4638	Rieske (2fe-2S)
MIM_RS17280	COG3264	Mechanosensitive ion channel
MIM_RS17280	COG1511	domain protein
MIM_RS17285	COG1737	Transcriptional regulator
MIM_RS17290	COG3842	ATPase activity
MIM_RS17295	COG1175	transmembrane transport
MIM_RS17300	COG0395	ABC-type sugar transport system, permease component
MIM_RS17305	COG1653	transport
MIM_RS17310	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
MIM_RS17315	COG1796	DNA polymerase
MIM_RS17315	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
MIM_RS17320	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIM_RS17320	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MIM_RS17325	COG0509	glycine decarboxylation via glycine cleavage system
MIM_RS17330	COG0404	The glycine cleavage system catalyzes the degradation of glycine
MIM_RS17345	COG2081	HI0933 family
MIM_RS17355	COG0717	Belongs to the dCTP deaminase family
MIM_RS17370	COG0489	protein tyrosine kinase activity
MIM_RS17390	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS17395	COG1902	pentaerythritol trinitrate reductase activity
MIM_RS17420	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIM_RS17420	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MIM_RS17440	COG1652	LysM domain
MIM_RS17445	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
MIM_RS17455	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MIM_RS17460	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIM_RS17470	COG3023	N-Acetylmuramoyl-L-alanine amidase
MIM_RS17480	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS17485	COG0583	DNA-binding transcription factor activity
MIM_RS17490	COG0326	Molecular chaperone. Has ATPase activity
MIM_RS17535	COG5290	Psort location Cytoplasmic, score
MIM_RS17570	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIM_RS17620	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS17680	COG3069	C4-dicarboxylate transmembrane transporter activity
MIM_RS17690	COG2186	Transcriptional regulator
MIM_RS17695	COG0730	response to heat
MIM_RS17725	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
MIM_RS17750	COG0583	DNA-binding transcription factor activity
MIM_RS17760	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
MIM_RS17775	COG2814	Major facilitator Superfamily
MIM_RS17780	COG0667	Aldo Keto reductase
MIM_RS17785	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_RS17800	COG2207	Transcriptional regulator
MIM_RS17815	COG1566	PFAM secretion protein HlyD family protein
MIM_RS17895	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS17900	COG1116	anion transmembrane transporter activity
MIM_RS17905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_RS17910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS17960	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS17980	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
MIM_RS17985	COG1116	anion transmembrane transporter activity
MIM_RS17990	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS17995	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
MIM_RS17995	COG1116	anion transmembrane transporter activity
MIM_RS18000	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIM_RS18025	COG1335	isochorismatase
MIM_RS18030	COG3119	arylsulfatase activity
MIM_RS18035	COG2207	Transcriptional regulator
MIM_RS18040	COG1335	isochorismatase
MIM_RS18045	COG0154	amidase activity
MIM_RS18050	COG1309	transcriptional regulator
MIM_RS18055	COG2814	Major facilitator Superfamily
MIM_RS18075	COG0596	Alpha beta hydrolase
MIM_RS18130	COG3842	ATPase activity
MIM_RS18140	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
MIM_RS18155	COG3177	Filamentation induced by cAMP protein fic
MIM_RS18165	COG3135	benzoate transporter
MIM_RS18170	COG1024	Enoyl-CoA hydratase
MIM_RS18215	COG0596	Alpha beta hydrolase
MIM_RS18225	COG0583	DNA-binding transcription factor activity
MIM_RS18245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
MIM_RS18250	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_RS18255	COG3833	ABC-type maltose transport systems, permease component
MIM_RS18260	COG3842	ATPase activity
MIM_RS18270	COG3214	Protein conserved in bacteria
MIM_RS18285	COG0583	DNA-binding transcription factor activity
MIM_RS18295	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS18315	COG3971	2-oxopent-4-enoate hydratase activity
MIM_RS18320	COG0179	Fumarylacetoacetate (FAA) hydrolase
MIM_RS18340	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_RS18390	COG3422	double-strand break repair
MIM_RS18400	COG1764	response to oxidative stress
MIM_RS18410	COG4172	Belongs to the ABC transporter superfamily
MIM_RS18415	COG1609	Transcriptional regulator
MIM_RS18425	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS18435	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS18460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
MIM_RS18475	COG0747	negative chemotaxis
MIM_RS18490	COG0410	ABC transporter
MIM_RS18560	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
MIM_RS18570	COG3246	L-lysine catabolic process to acetate
MIM_RS18655	COG2831	hemolysin activation secretion protein
MIM_RS18685	COG3609	addiction module antidote protein, CC2985 family
MIM_RS18695	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS18710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS18720	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS18725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS18730	COG2358	TRAP transporter, solute receptor (TAXI family
MIM_RS18745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_RS18755	COG0778	Nitroreductase
MIM_RS18770	COG4608	Belongs to the ABC transporter superfamily
MIM_RS18775	COG0444	Belongs to the ABC transporter superfamily
MIM_RS18780	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MIM_RS18795	COG0583	DNA-binding transcription factor activity
MIM_RS18825	COG2084	Dehydrogenase
MIM_RS18860	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS18875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS18935	COG4771	TonB-dependent receptor
MIM_RS18940	COG4607	ABC-type enterochelin transport system periplasmic component
MIM_RS18945	COG0583	DNA-binding transcription factor activity
MIM_RS18950	COG0667	Aldo Keto reductase
MIM_RS18960	COG3420	alginic acid biosynthetic process
MIM_RS18965	COG3485	protocatechuate 3,4-dioxygenase
MIM_RS18970	COG3485	protocatechuate 3,4-dioxygenase
MIM_RS18975	COG2271	Major facilitator Superfamily
MIM_RS18980	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MIM_RS18985	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
MIM_RS18990	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
MIM_RS18995	COG1414	Transcriptional regulator
MIM_RS19005	COG0583	DNA-binding transcription factor activity
MIM_RS19020	COG0066	3-isopropylmalate dehydratase activity
MIM_RS19030	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
MIM_RS19045	COG1175	transmembrane transport
MIM_RS19050	COG1840	ABC-type Fe3 transport system, periplasmic component
MIM_RS19055	COG1609	Transcriptional regulator
MIM_RS19080	COG1309	transcriptional regulator
MIM_RS19085	COG0655	NAD(P)H dehydrogenase (quinone) activity
MIM_RS19090	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_RS19095	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS19100	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
MIM_RS19105	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS19110	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS19115	COG1024	Enoyl-CoA hydratase
MIM_RS19125	COG1414	Transcriptional regulator
MIM_RS19130	COG0604	alcohol dehydrogenase
MIM_RS19135	COG0159	tryptophan synthase activity
MIM_RS19140	COG0133	tryptophan synthase activity
MIM_RS19155	COG1335	isochorismatase
MIM_RS19165	COG0583	DNA-binding transcription factor activity
MIM_RS19170	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
MIM_RS19215	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
MIM_RS19220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
MIM_RS19255	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS19260	COG1959	2 iron, 2 sulfur cluster binding
MIM_RS19265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
MIM_RS19265	COG1017	nitric oxide dioxygenase activity
MIM_RS19270	COG2860	membrane
MIM_RS19275	COG1113	amino acid transport
MIM_RS19280	COG0629	single-stranded DNA binding
MIM_RS19285	COG0803	Belongs to the bacterial solute-binding protein 9 family
MIM_RS19290	COG1115	amino acid carrier protein
MIM_RS19295	COG0748	coenzyme F420 binding
MIM_RS19325	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
MIM_RS19330	COG0477	Major facilitator Superfamily
MIM_RS19340	COG1414	Transcriptional regulator
MIM_RS19350	COG0523	cobalamin synthesis protein
MIM_RS19355	COG1228	amidohydrolase
MIM_RS19365	COG0280	phosphate acetyltransferase
MIM_RS19380	COG1414	Transcriptional regulator
MIM_RS19385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MIM_RS19390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS19395	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
MIM_RS19400	COG4521	taurine ABC transporter
MIM_RS19405	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS19410	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS19420	COG0446	pyridine nucleotide-disulphide oxidoreductase
MIM_RS19450	COG0583	DNA-binding transcription factor activity
MIM_RS19460	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
MIM_RS19465	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
MIM_RS19475	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS19480	COG4948	Mandelate Racemase Muconate Lactonizing
MIM_RS19485	COG2186	Transcriptional regulator
MIM_RS19520	COG1252	NADH dehydrogenase
MIM_RS19525	COG1960	acyl-CoA dehydrogenase activity
MIM_RS19540	COG1607	acyl-coa hydrolase
MIM_RS19565	COG4206	TonB-dependent receptor
MIM_RS19570	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
MIM_RS19575	COG0492	ferredoxin-NADP+ reductase activity
MIM_RS19585	COG0037	tRNA processing
MIM_RS19590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MIM_RS19590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
MIM_RS19600	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
MIM_RS19605	COG2890	protein-(glutamine-N5) methyltransferase activity
MIM_RS19610	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
MIM_RS19660	COG2188	Transcriptional regulator
MIM_RS19665	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
MIM_RS19670	COG3395	kinase activity
MIM_RS19685	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS19690	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS19700	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS19705	COG0390	transport system, permease component
MIM_RS19710	COG4619	ABC transporter
MIM_RS19725	COG1487	ribonuclease activity
MIM_RS19740	COG0280	phosphate acetyltransferase
MIM_RS19740	COG0281	malic enzyme
MIM_RS19745	COG0583	DNA-binding transcription factor activity
MIM_RS19785	COG0534	Mate efflux family protein
MIM_RS19790	COG0583	DNA-binding transcription factor activity
MIM_RS19810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS19820	COG0765	amino acid transport
MIM_RS19825	COG1126	abc transporter atp-binding protein
MIM_RS19830	COG0583	DNA-binding transcription factor activity
MIM_RS19845	COG2301	Belongs to the HpcH HpaI aldolase family
MIM_RS19855	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS19875	COG2188	Transcriptional regulator
MIM_RS19880	COG2721	sulfolactate sulfo-lyase activity
MIM_RS19885	COG2721	sulfolactate sulfo-lyase activity
MIM_RS19890	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS19895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_RS19985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
MIM_RS19990	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MIM_RS20005	COG1596	polysaccharide export
MIM_RS20025	COG2610	gluconate transmembrane transporter activity
MIM_RS20035	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
MIM_RS20065	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_RS20070	COG3842	ATPase activity
MIM_RS20100	COG1566	PFAM secretion protein HlyD family protein
MIM_RS20105	COG2814	Major facilitator Superfamily
MIM_RS20160	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_RS20180	COG0028	Belongs to the TPP enzyme family
MIM_RS20185	COG0583	DNA-binding transcription factor activity
MIM_RS20190	COG1126	abc transporter atp-binding protein
MIM_RS20195	COG0765	amino acid transport
MIM_RS20200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MIM_RS20205	COG0626	cystathionine gamma-synthase activity
MIM_RS20215	COG0697	spore germination
MIM_RS20220	COG2375	cellular response to nickel ion
MIM_RS20225	COG1695	Transcriptional regulator
MIM_RS20235	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
MIM_RS20240	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS20245	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS20260	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS20275	COG1960	acyl-CoA dehydrogenase activity
MIM_RS20285	COG1024	Enoyl-CoA hydratase
MIM_RS20290	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
MIM_RS20295	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
MIM_RS20300	COG0583	DNA-binding transcription factor activity
MIM_RS20310	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS20315	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS20320	COG4993	Dehydrogenase
MIM_RS20335	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
MIM_RS20345	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
MIM_RS20380	COG0583	DNA-binding transcription factor activity
MIM_RS20405	COG2814	Major facilitator Superfamily
MIM_RS20415	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
MIM_RS20425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
MIM_RS20430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MIM_RS20435	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
MIM_RS20450	COG1965	Belongs to the frataxin family
MIM_RS20465	COG2175	clavaminate synthase activity
MIM_RS20475	COG1116	anion transmembrane transporter activity
MIM_RS20480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
MIM_RS20485	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
MIM_RS20490	COG1333	cytochrome c biogenesis protein
MIM_RS20500	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MIM_RS20530	COG0318	PFAM AMP-dependent synthetase and ligase
MIM_RS20555	COG4232	protein-disulfide reductase activity
MIM_RS20560	COG1324	tolerance protein
MIM_RS20565	COG2814	Major facilitator Superfamily
MIM_RS20580	COG0203	ribosomal protein L17
MIM_RS20585	COG0202	RNA polymerase activity
MIM_RS20595	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MIM_RS20600	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MIM_RS20610	COG0201	protein transport
MIM_RS20615	COG0200	Binds to the 23S rRNA
MIM_RS20620	COG1841	ribosomal large subunit assembly
MIM_RS20625	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MIM_RS20630	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
MIM_RS20640	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MIM_RS20645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MIM_RS20650	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MIM_RS20655	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MIM_RS20660	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MIM_RS20665	COG0395	ABC-type sugar transport system, permease component
MIM_RS20670	COG1176	ABC-type spermidine putrescine transport system, permease component I
MIM_RS20680	COG3842	ATPase activity
MIM_RS20685	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
MIM_RS20730	COG4993	Dehydrogenase
MIM_RS20735	COG1414	Transcriptional regulator
MIM_RS20740	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS20755	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS20785	COG0411	ABC transporter
MIM_RS20795	COG0640	Transcriptional regulator
MIM_RS20820	COG3622	Belongs to the hyi family
MIM_RS20825	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
MIM_RS20830	COG0800	Aldolase
MIM_RS20835	COG0277	FAD linked oxidase domain protein
MIM_RS20840	COG0129	dihydroxy-acid dehydratase activity
MIM_RS20845	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
MIM_RS20850	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
MIM_RS20855	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
MIM_RS20860	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS20905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIM_RS20910	COG0800	Aldolase
MIM_RS20915	COG3734	2-keto-3-deoxy-galactonokinase
MIM_RS20920	COG0277	FAD linked oxidase domain protein
MIM_RS20925	COG0277	FAD linked oxidase domain protein
MIM_RS20930	COG3128	pkhd-type hydroxylase
MIM_RS20935	COG4774	siderophore transport
MIM_RS20945	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
MIM_RS20950	COG0255	Belongs to the universal ribosomal protein uL29 family
MIM_RS20955	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MIM_RS20960	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MIM_RS20965	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MIM_RS20975	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MIM_RS20980	COG0089	rRNA binding
MIM_RS20985	COG0088	Forms part of the polypeptide exit tunnel
MIM_RS20990	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MIM_RS21000	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
MIM_RS21005	COG1012	belongs to the aldehyde dehydrogenase family
MIM_RS21015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
MIM_RS21020	COG1172	Belongs to the binding-protein-dependent transport system permease family
MIM_RS21040	COG1349	DNA-binding transcription factor activity
MIM_RS21095	COG2308	Evidence 4 Homologs of previously reported genes of
MIM_RS21105	COG2308	Evidence 4 Homologs of previously reported genes of
MIM_RS21120	COG1322	Protein conserved in bacteria
MIM_RS21150	COG2011	ABC-type metal ion transport system permease component
MIM_RS21160	COG0051	transcription antitermination factor activity, RNA binding
MIM_RS21165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIM_RS21170	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MIM_RS21175	COG0049	tRNA binding
MIM_RS21180	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MIM_RS21185	COG0745	RESPONSE REGULATOR receiver
MIM_RS21195	COG2205	protein histidine kinase activity
MIM_RS21195	COG0784	Response regulator, receiver
MIM_RS21200	COG2301	Belongs to the HpcH HpaI aldolase family
MIM_RS21205	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS21210	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
MIM_RS21215	COG0583	DNA-binding transcription factor activity
MIM_RS21220	COG1960	acyl-CoA dehydrogenase activity
MIM_RS21245	COG3313	Fe-S protein
MIM_RS21285	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS21290	COG1802	Transcriptional regulator
MIM_RS21300	COG1250	3-hydroxyacyl-CoA dehydrogenase
MIM_RS21305	COG3246	L-lysine catabolic process to acetate
MIM_RS21310	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS21345	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MIM_RS21365	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
MIM_RS21395	COG1028	Short-chain dehydrogenase reductase Sdr
MIM_RS21400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MIM_RS21415	COG0596	Alpha beta hydrolase
MIM_RS21420	COG0583	DNA-binding transcription factor activity
MIM_RS21425	COG2423	ornithine cyclodeaminase activity
MIM_RS21430	COG1522	sequence-specific DNA binding
MIM_RS21440	COG2133	pyrroloquinoline quinone binding
MIM_RS21445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
MIM_RS21450	COG3344	reverse transcriptase
MIM_RS21460	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MIM_RS21465	COG0085	RNA polymerase activity
MIM_RS21470	COG0222	ribosome binding
MIM_RS21475	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MIM_RS21480	COG0081	regulation of translation
MIM_RS21485	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MIM_RS21495	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MIM_RS21505	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MIM_RS21525	COG1475	DNA binding
MIM_RS21530	COG1192	Involved in chromosome partitioning
MIM_RS21535	COG0357	Ribosomal RNA small subunit methyltransferase G
MIM_RS21540	COG0445	tRNA wobble uridine modification
MIM_RS21545	COG0436	Aminotransferase
MIM_RS21560	COG0537	adenosine 5'-monophosphoramidase activity
MIM_RS21570	COG0477	Major facilitator Superfamily
MIM_RS21575	COG3180	Ammonia monooxygenase
MIM_RS21580	COG0583	DNA-binding transcription factor activity
MIM_RS21625	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MIM_RS21630	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
MIM_RS21640	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
MIM_RS21665	COG0842	Transport permease protein
MIM_RS21670	COG0842	Transport permease protein
MIM_RS21675	COG1131	(ABC) transporter
MIM_RS21690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
MIM_RS21695	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
MIM_RS21700	COG0583	DNA-binding transcription factor activity
MIM_RS21720	COG1042	CoA-binding domain protein
MIM_RS21720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
MIM_RS21720	COG0045	succinate-CoA ligase (ADP-forming) activity
MIM_RS21725	COG1960	acyl-CoA dehydrogenase activity
MIM_RS21735	COG3181	Tripartite tricarboxylate transporter family receptor
MIM_RS21740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MIM_RS21745	COG0583	DNA-binding transcription factor activity
MIM_RS21750	COG0706	membrane insertase activity
MIM_RS21755	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MIM_RS21760	COG0594	ribonuclease P activity
MIM_RS21765	COG0230	Belongs to the bacterial ribosomal protein bL34 family
MIM_RS21775	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MIM_RS21935	COG0210	DNA helicase
MIM_RS21975	COG2755	lipolytic protein G-D-S-L family
MIM_RS21975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
MIM_RS22020	COG1690	Belongs to the RtcB family
MIM_RS22070	COG2010	Cytochrome c
MIM_RS22080	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
MIM_RS22165	COG1573	uracil-dna glycosylase
MIM_RS22280	COG0745	RESPONSE REGULATOR receiver