locus-tag	class	description
AEQSU_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AEQSU_RS00070	COG2217	Heavy metal translocating P-type atpase
AEQSU_RS00105	COG0069	glutamate synthase activity
AEQSU_RS00110	COG0028	Belongs to the TPP enzyme family
AEQSU_RS00140	COG3273	potassium ion transport
AEQSU_RS00140	COG0471	metal ion transport
AEQSU_RS00145	COG0668	transmembrane transport
AEQSU_RS00160	COG0300	oxidoreductase activity
AEQSU_RS00170	COG3264	Mechanosensitive ion channel
AEQSU_RS00170	COG1196	nuclear chromosome segregation
AEQSU_RS00175	COG2814	Major facilitator Superfamily
AEQSU_RS00180	COG0668	transmembrane transport
AEQSU_RS00185	COG1607	acyl-coa hydrolase
AEQSU_RS00190	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
AEQSU_RS00195	COG0519	Catalyzes the synthesis of GMP from XMP
AEQSU_RS00195	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AEQSU_RS00200	COG1388	LysM domain
AEQSU_RS00200	COG3942	CHAP domain
AEQSU_RS00215	COG3530	Putative quorum-sensing-regulated virulence factor
AEQSU_RS00225	COG0504	CTP synthase activity
AEQSU_RS00230	COG0706	membrane insertase activity
AEQSU_RS00240	COG0482	sulfurtransferase activity
AEQSU_RS00255	COG2342	PFAM TM1410 hypothetical-related protein
AEQSU_RS00265	COG1278	Cold shock
AEQSU_RS00275	COG0019	diaminopimelate decarboxylase activity
AEQSU_RS00280	COG0045	succinate-CoA ligase (ADP-forming) activity
AEQSU_RS00295	COG1187	pseudouridine synthase activity
AEQSU_RS00330	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEQSU_RS00335	COG0631	protein serine/threonine phosphatase activity
AEQSU_RS00385	COG3609	addiction module antidote protein, CC2985 family
AEQSU_RS00405	COG4680	protein conserved in bacteria
AEQSU_RS00435	COG2855	membrane
AEQSU_RS00440	COG0668	transmembrane transport
AEQSU_RS00465	COG2814	Major facilitator Superfamily
AEQSU_RS00470	COG2351	hydroxyisourate hydrolase activity
AEQSU_RS00530	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQSU_RS00565	COG0348	domain, Protein
AEQSU_RS00590	COG2217	Heavy metal translocating P-type atpase
AEQSU_RS00615	COG4221	oxidoreductase activity
AEQSU_RS00665	COG0427	acetyl-CoA hydrolase
AEQSU_RS00680	COG1131	(ABC) transporter
AEQSU_RS00700	COG4263	nitrous-oxide reductase activity
AEQSU_RS00705	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AEQSU_RS00735	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS00740	COG2205	protein histidine kinase activity
AEQSU_RS00760	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AEQSU_RS00765	COG0813	purine-nucleoside phosphorylase activity
AEQSU_RS00770	COG0589	response to stress
AEQSU_RS00790	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEQSU_RS00820	COG2827	Endonuclease containing a URI domain
AEQSU_RS00855	COG0732	type I restriction modification DNA specificity domain
AEQSU_RS00950	COG1525	nuclease
AEQSU_RS01005	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AEQSU_RS01010	COG0500	methyltransferase
AEQSU_RS01025	COG0708	Exodeoxyribonuclease III
AEQSU_RS01035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEQSU_RS01040	COG0439	Biotin carboxylase
AEQSU_RS01055	COG2133	pyrroloquinoline quinone binding
AEQSU_RS01065	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AEQSU_RS01075	COG1475	DNA binding
AEQSU_RS01080	COG1192	Involved in chromosome partitioning
AEQSU_RS01085	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS01110	COG1012	belongs to the aldehyde dehydrogenase family
AEQSU_RS01135	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AEQSU_RS01145	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AEQSU_RS01170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AEQSU_RS01190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AEQSU_RS01190	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEQSU_RS01200	COG2234	aminopeptidase activity
AEQSU_RS01210	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AEQSU_RS01215	COG0626	cystathionine gamma-synthase activity
AEQSU_RS01225	COG0456	acetyltransferase
AEQSU_RS01235	COG0336	Belongs to the RNA methyltransferase TrmD family
AEQSU_RS01255	COG0640	Transcriptional regulator
AEQSU_RS01260	COG5658	integral membrane protein
AEQSU_RS01265	COG0335	large ribosomal subunit rRNA binding
AEQSU_RS01285	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AEQSU_RS01325	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AEQSU_RS01330	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AEQSU_RS01335	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AEQSU_RS01340	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AEQSU_RS01360	COG0305	Participates in initiation and elongation during chromosome replication
AEQSU_RS01365	COG0825	malonyl-CoA metabolic process
AEQSU_RS01385	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AEQSU_RS01390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEQSU_RS01405	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AEQSU_RS01410	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AEQSU_RS01430	COG1233	COG1233 Phytoene dehydrogenase and related
AEQSU_RS01455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQSU_RS01465	COG0714	Associated with various cellular activities
AEQSU_RS01470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEQSU_RS01480	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEQSU_RS01500	COG0516	GMP reductase activity
AEQSU_RS01500	COG0517	IMP dehydrogenase activity
AEQSU_RS01510	COG0737	Belongs to the 5'-nucleotidase family
AEQSU_RS01520	COG1280	lysine exporter protein (LysE YggA)
AEQSU_RS01525	COG0167	dihydroorotate dehydrogenase activity
AEQSU_RS01535	COG2195	Cleaves the N-terminal amino acid of tripeptides
AEQSU_RS01540	COG1862	Preprotein translocase
AEQSU_RS01550	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEQSU_RS01565	COG1132	(ABC) transporter
AEQSU_RS01575	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AEQSU_RS01590	COG0659	secondary active sulfate transmembrane transporter activity
AEQSU_RS01600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQSU_RS01615	COG2318	DinB family
AEQSU_RS01620	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEQSU_RS01645	COG1131	(ABC) transporter
AEQSU_RS01705	COG2264	protein methyltransferase activity
AEQSU_RS01720	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEQSU_RS01725	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
AEQSU_RS01745	COG2326	polyphosphate kinase activity
AEQSU_RS01750	COG2204	response regulator
AEQSU_RS01760	COG1668	transmembrane transport
AEQSU_RS01765	COG4152	abc transporter atp-binding protein
AEQSU_RS01770	COG0484	heat shock protein binding
AEQSU_RS01775	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AEQSU_RS01790	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEQSU_RS01790	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AEQSU_RS01800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AEQSU_RS01850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEQSU_RS01875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AEQSU_RS01900	COG1522	sequence-specific DNA binding
AEQSU_RS01925	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AEQSU_RS01925	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AEQSU_RS01925	COG1703	isobutyryl-CoA mutase activity
AEQSU_RS01955	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AEQSU_RS01960	COG0284	orotidine-5'-phosphate decarboxylase activity
AEQSU_RS01965	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AEQSU_RS01970	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AEQSU_RS02025	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AEQSU_RS02040	COG2264	protein methyltransferase activity
AEQSU_RS02045	COG0149	triose-phosphate isomerase activity
AEQSU_RS02050	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQSU_RS02055	COG0601	transmembrane transport
AEQSU_RS02070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AEQSU_RS02075	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AEQSU_RS02080	COG1132	(ABC) transporter
AEQSU_RS02085	COG0101	tRNA pseudouridine synthase activity
AEQSU_RS02105	COG3279	Response regulator of the LytR AlgR family
AEQSU_RS02130	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AEQSU_RS02140	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AEQSU_RS02140	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AEQSU_RS02145	COG0799	negative regulation of ribosome biogenesis
AEQSU_RS02150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AEQSU_RS02160	COG4589	Belongs to the CDS family
AEQSU_RS02165	COG0688	phosphatidylethanolamine metabolic process
AEQSU_RS02185	COG0525	valine-tRNA ligase activity
AEQSU_RS02200	COG0436	Aminotransferase
AEQSU_RS02205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AEQSU_RS02220	COG1215	transferase activity, transferring glycosyl groups
AEQSU_RS02230	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AEQSU_RS02235	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AEQSU_RS02245	COG1663	tetraacyldisaccharide 4'-kinase activity
AEQSU_RS02250	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AEQSU_RS02260	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEQSU_RS02290	COG3844	kynureninase activity
AEQSU_RS02295	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEQSU_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS02325	COG3104	oligopeptide transport
AEQSU_RS02330	COG4122	O-methyltransferase activity
AEQSU_RS02335	COG0671	phosphoesterase, PA-phosphatase related
AEQSU_RS02340	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQSU_RS02370	COG3340	Belongs to the peptidase S51 family
AEQSU_RS02385	COG1876	peptidase activity
AEQSU_RS02390	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AEQSU_RS02415	COG1477	protein flavinylation
AEQSU_RS02430	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AEQSU_RS02435	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AEQSU_RS02440	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
AEQSU_RS02445	COG1805	sodium ion transport
AEQSU_RS02470	COG2967	ApaG domain
AEQSU_RS02480	COG1012	belongs to the aldehyde dehydrogenase family
AEQSU_RS02490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQSU_RS02520	COG0357	Ribosomal RNA small subunit methyltransferase G
AEQSU_RS02525	COG3239	Fatty acid desaturase
AEQSU_RS02530	COG0436	Aminotransferase
AEQSU_RS02540	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AEQSU_RS02555	COG2226	methyltransferase
AEQSU_RS02565	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEQSU_RS02575	COG0191	fructose-bisphosphate aldolase activity
AEQSU_RS02580	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AEQSU_RS02585	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AEQSU_RS02590	COG1185	polyribonucleotide nucleotidyltransferase activity
AEQSU_RS02635	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AEQSU_RS02640	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AEQSU_RS02645	COG0492	ferredoxin-NADP+ reductase activity
AEQSU_RS02660	COG1629	transport
AEQSU_RS02680	COG4206	TonB-dependent receptor
AEQSU_RS02680	COG1629	transport
AEQSU_RS02685	COG2217	Heavy metal translocating P-type atpase
AEQSU_RS02720	COG0138	bifunctional purine biosynthesis protein purh
AEQSU_RS02725	COG1077	Cell shape determining protein MreB Mrl
AEQSU_RS02740	COG0768	penicillin binding
AEQSU_RS02745	COG0772	Belongs to the SEDS family
AEQSU_RS02755	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
AEQSU_RS02765	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AEQSU_RS02775	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AEQSU_RS02780	COG0268	Binds directly to 16S ribosomal RNA
AEQSU_RS02790	COG0442	prolyl-tRNA aminoacylation
AEQSU_RS02805	COG0302	gtp cyclohydrolase
AEQSU_RS02810	COG0215	cysteine-tRNA ligase activity
AEQSU_RS02815	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AEQSU_RS02820	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AEQSU_RS02830	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AEQSU_RS02855	COG0187	DNA topoisomerase II activity
AEQSU_RS02865	COG0602	queuosine metabolic process
AEQSU_RS02875	COG0433	COG0433 Predicted ATPase
AEQSU_RS02910	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AEQSU_RS02920	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AEQSU_RS02925	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AEQSU_RS02930	COG1506	peptidase
AEQSU_RS02930	COG0823	Involved in the tonB-independent uptake of proteins
AEQSU_RS02945	COG0531	amino acid
AEQSU_RS02955	COG2226	methyltransferase
AEQSU_RS02965	COG0513	Belongs to the DEAD box helicase family
AEQSU_RS02990	COG3279	Response regulator of the LytR AlgR family
AEQSU_RS03050	COG2267	carboxylic ester hydrolase activity
AEQSU_RS03060	COG0288	reversible hydration of carbon dioxide
AEQSU_RS03065	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AEQSU_RS03075	COG0018	arginyl-trna synthetase
AEQSU_RS03085	COG2095	MarC family integral membrane protein
AEQSU_RS03110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQSU_RS03115	COG1477	protein flavinylation
AEQSU_RS03135	COG1054	Belongs to the UPF0176 family
AEQSU_RS03140	COG1054	Belongs to the UPF0176 family
AEQSU_RS03145	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AEQSU_RS03150	COG0512	Glutamine amidotransferase of anthranilate synthase
AEQSU_RS03155	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AEQSU_RS03160	COG0134	indole-3-glycerol-phosphate synthase activity
AEQSU_RS03165	COG0135	phosphoribosylanthranilate isomerase activity
AEQSU_RS03170	COG0133	tryptophan synthase activity
AEQSU_RS03175	COG0159	tryptophan synthase activity
AEQSU_RS03200	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AEQSU_RS03230	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AEQSU_RS03235	COG3483	tryptophan 2,3-dioxygenase activity
AEQSU_RS03240	COG3189	MarR family transcriptional regulator
AEQSU_RS03265	COG4771	TonB-dependent receptor
AEQSU_RS03295	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AEQSU_RS03320	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AEQSU_RS03330	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AEQSU_RS03350	COG1215	transferase activity, transferring glycosyl groups
AEQSU_RS03365	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEQSU_RS03375	COG0321	lipoyl(octanoyl) transferase activity
AEQSU_RS03405	COG2197	response regulator
AEQSU_RS03410	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AEQSU_RS03420	COG0563	adenylate kinase activity
AEQSU_RS03425	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AEQSU_RS03445	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEQSU_RS03445	COG0022	dehydrogenase e1 component
AEQSU_RS03455	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AEQSU_RS03465	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
AEQSU_RS03470	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AEQSU_RS03485	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEQSU_RS03490	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AEQSU_RS03505	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AEQSU_RS03515	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AEQSU_RS03530	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEQSU_RS03550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AEQSU_RS03565	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AEQSU_RS03565	COG1519	Transferase
AEQSU_RS03580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AEQSU_RS03590	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AEQSU_RS03595	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AEQSU_RS03685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AEQSU_RS03695	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AEQSU_RS03700	COG1902	pentaerythritol trinitrate reductase activity
AEQSU_RS03710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AEQSU_RS03725	COG4558	Periplasmic binding protein
AEQSU_RS03730	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQSU_RS03775	COG2081	HI0933 family
AEQSU_RS03780	COG0076	glutamate decarboxylase activity
AEQSU_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS03820	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AEQSU_RS03875	COG2824	Alkylphosphonate utilization operon protein PhnA
AEQSU_RS03915	COG0488	(ABC) transporter
AEQSU_RS03925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AEQSU_RS03925	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AEQSU_RS03945	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEQSU_RS03960	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQSU_RS03985	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AEQSU_RS03995	COG0459	protein refolding
AEQSU_RS04015	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEQSU_RS04015	COG3153	acetyltransferase
AEQSU_RS04030	COG1899	peptidyl-lysine modification to peptidyl-hypusine
AEQSU_RS04035	COG0010	Belongs to the arginase family
AEQSU_RS04045	COG1187	pseudouridine synthase activity
AEQSU_RS04050	COG1428	Deoxynucleoside kinase
AEQSU_RS04075	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AEQSU_RS04085	COG0544	peptidyl-prolyl cis-trans isomerase activity
AEQSU_RS04090	COG1950	PFAM Membrane protein of
AEQSU_RS04105	COG0596	Alpha beta hydrolase
AEQSU_RS04115	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AEQSU_RS04125	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AEQSU_RS04135	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AEQSU_RS04155	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AEQSU_RS04160	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AEQSU_RS04170	COG3279	Response regulator of the LytR AlgR family
AEQSU_RS04175	COG3275	phosphorelay sensor kinase activity
AEQSU_RS04195	COG0822	iron-sulfur transferase activity
AEQSU_RS04195	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AEQSU_RS04195	COG2906	2 iron, 2 sulfur cluster binding
AEQSU_RS04205	COG1331	Highly conserved protein containing a thioredoxin domain
AEQSU_RS04210	COG0668	transmembrane transport
AEQSU_RS04225	COG1214	PFAM Peptidase M22, glycoprotease
AEQSU_RS04230	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEQSU_RS04240	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEQSU_RS04250	COG1136	(ABC) transporter
AEQSU_RS04250	COG0577	efflux transmembrane transporter activity
AEQSU_RS04255	COG1136	(ABC) transporter
AEQSU_RS04255	COG0577	efflux transmembrane transporter activity
AEQSU_RS04260	COG1136	(ABC) transporter
AEQSU_RS04270	COG2322	membrane
AEQSU_RS04275	COG1999	signal sequence binding
AEQSU_RS04320	COG1845	cytochrome c oxidase, subunit III
AEQSU_RS04325	COG0109	protoheme IX farnesyltransferase activity
AEQSU_RS04355	COG0509	glycine decarboxylation via glycine cleavage system
AEQSU_RS04365	COG0632	four-way junction helicase activity
AEQSU_RS04380	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AEQSU_RS04390	COG2255	four-way junction helicase activity
AEQSU_RS04395	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AEQSU_RS04425	COG0437	4 iron, 4 sulfur cluster binding
AEQSU_RS04445	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AEQSU_RS04450	COG0195	Participates in both transcription termination and antitermination
AEQSU_RS04455	COG0779	Required for maturation of 30S ribosomal subunits
AEQSU_RS04460	COG0589	response to stress
AEQSU_RS04470	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AEQSU_RS04485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEQSU_RS04495	COG0463	Glycosyl transferase, family 2
AEQSU_RS04505	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEQSU_RS04530	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEQSU_RS04535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEQSU_RS04565	COG1131	(ABC) transporter
AEQSU_RS04585	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEQSU_RS04590	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEQSU_RS04605	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEQSU_RS04610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEQSU_RS04615	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS04625	COG2986	histidine ammonia-lyase
AEQSU_RS04675	COG3118	belongs to the thioredoxin family
AEQSU_RS04680	COG1408	metallophosphoesterase
AEQSU_RS04695	COG3537	Alpha-1,2-mannosidase
AEQSU_RS04705	COG1446	asparaginase
AEQSU_RS04735	COG0189	ligase activity
AEQSU_RS04735	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AEQSU_RS04740	COG4242	Belongs to the peptidase S51 family
AEQSU_RS04760	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEQSU_RS04760	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AEQSU_RS04780	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AEQSU_RS04785	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AEQSU_RS04790	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AEQSU_RS04795	COG0052	Belongs to the universal ribosomal protein uS2 family
AEQSU_RS04800	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AEQSU_RS04835	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AEQSU_RS04840	COG0756	dUTP diphosphatase activity
AEQSU_RS04855	COG0824	Thioesterase
AEQSU_RS04860	COG2239	Acts as a magnesium transporter
AEQSU_RS04865	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AEQSU_RS04895	COG2095	MarC family integral membrane protein
AEQSU_RS04905	COG0793	Belongs to the peptidase S41A family
AEQSU_RS05035	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AEQSU_RS05040	COG1061	Type III restriction enzyme res subunit
AEQSU_RS05045	COG1002	Type II restriction enzyme, methylase subunits
AEQSU_RS05065	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AEQSU_RS05070	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AEQSU_RS05075	COG0193	aminoacyl-tRNA hydrolase activity
AEQSU_RS05080	COG0196	riboflavin kinase activity
AEQSU_RS05090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AEQSU_RS05110	COG4771	TonB-dependent receptor
AEQSU_RS05115	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AEQSU_RS05135	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AEQSU_RS05140	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AEQSU_RS05145	COG1505	serine-type exopeptidase activity
AEQSU_RS05185	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AEQSU_RS05190	COG0860	N-Acetylmuramoyl-L-alanine amidase
AEQSU_RS05195	COG1970	mechanosensitive ion channel activity
AEQSU_RS05200	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AEQSU_RS05205	COG1435	thymidine kinase activity
AEQSU_RS05220	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AEQSU_RS05240	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AEQSU_RS05240	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AEQSU_RS05250	COG0720	synthase
AEQSU_RS05300	COG1074	ATP-dependent DNA helicase activity
AEQSU_RS05305	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AEQSU_RS05315	COG1105	Belongs to the carbohydrate kinase PfkB family
AEQSU_RS05320	COG0328	RNA-DNA hybrid ribonuclease activity
AEQSU_RS05320	COG3341	Caulimovirus viroplasmin
AEQSU_RS05330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEQSU_RS05335	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEQSU_RS05340	COG0571	ribonuclease III activity
AEQSU_RS05350	COG0469	pyruvate kinase activity
AEQSU_RS05360	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEQSU_RS05370	COG3647	Membrane
AEQSU_RS05375	COG2954	triphosphatase activity
AEQSU_RS05385	COG3525	Glycosyl hydrolase, family 20, catalytic domain
AEQSU_RS05390	COG3250	beta-galactosidase activity
AEQSU_RS05395	COG1538	Outer membrane efflux protein
AEQSU_RS05405	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AEQSU_RS05420	COG4953	penicillin-binding protein 1C
AEQSU_RS05430	COG1446	asparaginase
AEQSU_RS05445	COG1012	belongs to the aldehyde dehydrogenase family
AEQSU_RS05465	COG4260	virion core protein, lumpy skin disease virus
AEQSU_RS05475	COG4221	oxidoreductase activity
AEQSU_RS05480	COG0714	Associated with various cellular activities
AEQSU_RS05495	COG2304	oxidoreductase activity
AEQSU_RS05505	COG2304	oxidoreductase activity
AEQSU_RS05535	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AEQSU_RS05545	COG3842	ATPase activity
AEQSU_RS05550	COG2130	NADP-dependent
AEQSU_RS05555	COG1289	transmembrane transporter activity
AEQSU_RS05565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AEQSU_RS05575	COG0439	Biotin carboxylase
AEQSU_RS05580	COG0511	ligase activity, forming carbon-carbon bonds
AEQSU_RS05585	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEQSU_RS05590	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AEQSU_RS05600	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AEQSU_RS05605	COG0307	riboflavin synthase, alpha
AEQSU_RS05620	COG0346	lactoylglutathione lyase activity
AEQSU_RS05630	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AEQSU_RS05630	COG0517	IMP dehydrogenase activity
AEQSU_RS05630	COG0617	tRNA 3'-terminal CCA addition
AEQSU_RS05660	COG0123	including yeast histone deacetylase and acetoin utilization protein
AEQSU_RS05675	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQSU_RS05675	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AEQSU_RS05680	COG1619	proteins homologs of microcin C7 resistance protein MccF
AEQSU_RS05685	COG0792	nuclease activity
AEQSU_RS05695	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AEQSU_RS05715	COG1201	RNA secondary structure unwinding
AEQSU_RS05720	COG1793	dna ligase
AEQSU_RS05735	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AEQSU_RS05745	COG0460	homoserine dehydrogenase
AEQSU_RS05745	COG0527	aspartate kinase activity
AEQSU_RS05775	COG0346	lactoylglutathione lyase activity
AEQSU_RS05780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AEQSU_RS05800	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AEQSU_RS05805	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AEQSU_RS05810	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEQSU_RS05815	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AEQSU_RS05820	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AEQSU_RS05825	COG0356	it plays a direct role in the translocation of protons across the membrane
AEQSU_RS05850	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AEQSU_RS05890	COG0151	Belongs to the GarS family
AEQSU_RS05910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEQSU_RS05925	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AEQSU_RS05935	COG0673	inositol 2-dehydrogenase activity
AEQSU_RS05950	COG0367	asparagine synthase
AEQSU_RS05975	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AEQSU_RS05980	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AEQSU_RS06010	COG4942	peptidase
AEQSU_RS06015	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AEQSU_RS06030	COG1388	LysM domain
AEQSU_RS06030	COG1705	Flagellar rod assembly protein muramidase FlgJ
AEQSU_RS06035	COG0126	phosphoglycerate kinase activity
AEQSU_RS06050	COG0445	tRNA wobble uridine modification
AEQSU_RS06055	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AEQSU_RS06070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEQSU_RS06095	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AEQSU_RS06110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AEQSU_RS06135	COG0557	exoribonuclease II activity
AEQSU_RS06145	COG0698	ribose 5-phosphate isomerase
AEQSU_RS06155	COG2153	protein acetylation
AEQSU_RS06170	COG0793	Belongs to the peptidase S41A family
AEQSU_RS06180	COG0594	ribonuclease P activity
AEQSU_RS06195	COG1404	Belongs to the peptidase S8 family
AEQSU_RS06200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AEQSU_RS06205	COG3263	regulation of cellular component size
AEQSU_RS06220	COG0481	GTPase activity
AEQSU_RS06240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AEQSU_RS06245	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEQSU_RS06250	COG3590	peptidase
AEQSU_RS06260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEQSU_RS06280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEQSU_RS06285	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AEQSU_RS06285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AEQSU_RS06310	COG0750	zinc metalloprotease
AEQSU_RS06320	COG1999	signal sequence binding
AEQSU_RS06345	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AEQSU_RS06345	COG1321	iron dependent repressor
AEQSU_RS06350	COG4771	TonB-dependent receptor
AEQSU_RS06355	COG4232	protein-disulfide reductase activity
AEQSU_RS06360	COG0484	heat shock protein binding
AEQSU_RS06380	COG1418	mRNA catabolic process
AEQSU_RS06415	COG2936	dipeptidyl-peptidase activity
AEQSU_RS06420	COG1024	Enoyl-CoA hydratase
AEQSU_RS06425	COG5000	phosphorelay sensor kinase activity
AEQSU_RS06430	COG1981	membrane
AEQSU_RS06440	COG0534	Mate efflux family protein
AEQSU_RS06445	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AEQSU_RS06470	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AEQSU_RS06475	COG0181	hydroxymethylbilane synthase activity
AEQSU_RS06480	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
AEQSU_RS06495	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AEQSU_RS06510	COG0408	coproporphyrinogen oxidase activity
AEQSU_RS06520	COG0113	porphobilinogen synthase activity
AEQSU_RS06535	COG1253	flavin adenine dinucleotide binding
AEQSU_RS06540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AEQSU_RS06560	COG4172	Belongs to the ABC transporter superfamily
AEQSU_RS06565	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AEQSU_RS06570	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AEQSU_RS06575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
AEQSU_RS06585	COG1774	PSP1 C-terminal conserved region
AEQSU_RS06590	COG1054	Belongs to the UPF0176 family
AEQSU_RS06605	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AEQSU_RS06625	COG0180	Tryptophanyl-tRNA synthetase
AEQSU_RS06635	COG0758	DNA mediated transformation
AEQSU_RS06635	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AEQSU_RS06645	COG1607	acyl-coa hydrolase
AEQSU_RS06660	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AEQSU_RS06665	COG3743	rRNA binding
AEQSU_RS06665	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AEQSU_RS06685	COG0629	single-stranded DNA binding
AEQSU_RS06700	COG0776	regulation of translation
AEQSU_RS06705	COG1530	ribonuclease E activity
AEQSU_RS06730	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AEQSU_RS06750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AEQSU_RS06760	COG0297	glycogen (starch) synthase activity
AEQSU_RS06765	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AEQSU_RS06770	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AEQSU_RS06785	COG2197	response regulator
AEQSU_RS06790	COG4585	Histidine kinase
AEQSU_RS06795	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AEQSU_RS06805	COG1960	acyl-CoA dehydrogenase activity
AEQSU_RS06810	COG0667	Aldo Keto reductase
AEQSU_RS06820	COG0708	Exodeoxyribonuclease III
AEQSU_RS06840	COG0423	glycine-tRNA ligase activity
AEQSU_RS06865	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AEQSU_RS06870	COG0436	Aminotransferase
AEQSU_RS06875	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AEQSU_RS06885	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
AEQSU_RS06910	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AEQSU_RS06925	COG2205	protein histidine kinase activity
AEQSU_RS06925	COG3437	response regulator, receiver
AEQSU_RS06925	COG3850	Histidine kinase
AEQSU_RS06925	COG4999	Histidine kinase
AEQSU_RS06940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEQSU_RS06955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AEQSU_RS06955	COG0784	Response regulator, receiver
AEQSU_RS06955	COG2205	protein histidine kinase activity
AEQSU_RS06955	COG2198	Histidine kinase
AEQSU_RS06960	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AEQSU_RS06970	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AEQSU_RS06975	COG2957	Belongs to the agmatine deiminase family
AEQSU_RS06985	COG0519	Catalyzes the synthesis of GMP from XMP
AEQSU_RS06995	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AEQSU_RS07010	COG1968	undecaprenyl-diphosphatase activity
AEQSU_RS07020	COG2177	Part of the ABC transporter FtsEX involved in
AEQSU_RS07030	COG0495	leucyl-tRNA aminoacylation
AEQSU_RS07050	COG2363	Small membrane protein
AEQSU_RS07055	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
AEQSU_RS07065	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AEQSU_RS07110	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEQSU_RS07130	COG0084	hydrolase, TatD family'
AEQSU_RS07135	COG0252	asparaginase activity
AEQSU_RS07145	COG0811	peptide transport
AEQSU_RS07175	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AEQSU_RS07180	COG0017	Asparaginyl-tRNA synthetase
AEQSU_RS07200	COG0233	cytoplasmic translational termination
AEQSU_RS07205	COG0528	UMP kinase activity
AEQSU_RS07220	COG1053	succinate dehydrogenase
AEQSU_RS07235	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AEQSU_RS07250	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AEQSU_RS07270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEQSU_RS07275	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AEQSU_RS07280	COG2204	response regulator
AEQSU_RS07285	COG4191	Histidine kinase
AEQSU_RS07320	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AEQSU_RS07335	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AEQSU_RS07350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AEQSU_RS07360	COG0189	ligase activity
AEQSU_RS07365	COG0189	ligase activity
AEQSU_RS07365	COG4067	protein conserved in archaea
AEQSU_RS07370	COG0189	ligase activity
AEQSU_RS07375	COG0322	excinuclease ABC activity
AEQSU_RS07385	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
AEQSU_RS07395	COG3185	4-Hydroxyphenylpyruvate dioxygenase
AEQSU_RS07410	COG4771	TonB-dependent receptor
AEQSU_RS07455	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AEQSU_RS07470	COG2151	metal-sulfur cluster biosynthetic enzyme
AEQSU_RS07475	COG2166	iron-sulfur cluster assembly
AEQSU_RS07485	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AEQSU_RS07490	COG0719	Fe-S assembly protein
AEQSU_RS07500	COG0396	ATPase activity
AEQSU_RS07510	COG0719	Fe-S assembly protein
AEQSU_RS07515	COG0316	Belongs to the HesB IscA family
AEQSU_RS07540	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AEQSU_RS07550	COG0006	proline dipeptidase activity
AEQSU_RS07590	COG3547	Transposase (IS116 IS110 IS902 family)
AEQSU_RS07655	COG1012	belongs to the aldehyde dehydrogenase family
AEQSU_RS07660	COG0456	acetyltransferase
AEQSU_RS07665	COG1528	Iron-storage protein
AEQSU_RS07670	COG1381	Involved in DNA repair and RecF pathway recombination
AEQSU_RS07680	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AEQSU_RS07690	COG0626	cystathionine gamma-synthase activity
AEQSU_RS07715	COG0429	hydrolase of the alpha beta-hydrolase fold
AEQSU_RS07720	COG1561	YicC-like family, N-terminal region
AEQSU_RS07725	COG0194	GDP metabolic process
AEQSU_RS07730	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AEQSU_RS07745	COG0463	Glycosyl transferase, family 2
AEQSU_RS07760	COG0702	epimerase
AEQSU_RS07765	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AEQSU_RS07780	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS07785	COG5002	protein histidine kinase activity
AEQSU_RS07795	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AEQSU_RS07815	COG0489	protein tyrosine kinase activity
AEQSU_RS07825	COG0492	ferredoxin-NADP+ reductase activity
AEQSU_RS07835	COG1730	sister chromatid segregation
AEQSU_RS07890	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
AEQSU_RS07895	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AEQSU_RS07900	COG0228	four-way junction DNA binding
AEQSU_RS07925	COG0740	serine-type endopeptidase activity
AEQSU_RS07960	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEQSU_RS07985	COG0463	Glycosyl transferase, family 2
AEQSU_RS07995	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AEQSU_RS08000	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEQSU_RS08005	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AEQSU_RS08030	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AEQSU_RS08040	COG0415	Belongs to the DNA photolyase family
AEQSU_RS08045	COG3046	protein related to deoxyribodipyrimidine photolyase
AEQSU_RS08060	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AEQSU_RS08095	COG2272	Belongs to the type-B carboxylesterase lipase family
AEQSU_RS08140	COG4585	Histidine kinase
AEQSU_RS08145	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AEQSU_RS08190	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AEQSU_RS08220	COG0069	glutamate synthase activity
AEQSU_RS08250	COG1404	Belongs to the peptidase S8 family
AEQSU_RS08305	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AEQSU_RS08350	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AEQSU_RS08355	COG1705	Flagellar rod assembly protein muramidase FlgJ
AEQSU_RS08360	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AEQSU_RS08405	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AEQSU_RS08420	COG1960	acyl-CoA dehydrogenase activity
AEQSU_RS08440	COG0811	peptide transport
AEQSU_RS08445	COG0848	biopolymer transport protein
AEQSU_RS08475	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
AEQSU_RS08505	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AEQSU_RS08510	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AEQSU_RS08530	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AEQSU_RS08540	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS08575	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AEQSU_RS08580	COG1785	Belongs to the alkaline phosphatase family
AEQSU_RS08585	COG1215	transferase activity, transferring glycosyl groups
AEQSU_RS08600	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEQSU_RS08605	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEQSU_RS08605	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AEQSU_RS08640	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AEQSU_RS08645	COG2827	Endonuclease containing a URI domain
AEQSU_RS08650	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AEQSU_RS08695	COG0596	Alpha beta hydrolase
AEQSU_RS08730	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AEQSU_RS08740	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AEQSU_RS08750	COG1428	Deoxynucleoside kinase
AEQSU_RS08780	COG3186	Phenylalanine-4-hydroxylase
AEQSU_RS08790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AEQSU_RS08795	COG3396	Phenylacetate-CoA oxygenase
AEQSU_RS08800	COG3460	Phenylacetate-CoA oxygenase
AEQSU_RS08810	COG3396	Phenylacetate-CoA oxygenase
AEQSU_RS08815	COG2151	metal-sulfur cluster biosynthetic enzyme
AEQSU_RS08820	COG1024	Enoyl-CoA hydratase
AEQSU_RS08825	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEQSU_RS08835	COG2321	neutral zinc metallopeptidase
AEQSU_RS08840	COG0183	Belongs to the thiolase family
AEQSU_RS08855	COG2030	dehydratase
AEQSU_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
AEQSU_RS08870	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEQSU_RS08875	COG0022	dehydrogenase e1 component
AEQSU_RS08925	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AEQSU_RS08930	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AEQSU_RS08935	COG0739	heme binding
AEQSU_RS08945	COG1704	LemA family
AEQSU_RS08975	COG2364	Membrane
AEQSU_RS08980	COG1160	GTP binding
AEQSU_RS08995	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AEQSU_RS09035	COG4585	Histidine kinase
AEQSU_RS09050	COG2197	response regulator
AEQSU_RS09060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AEQSU_RS09065	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS09070	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS09085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEQSU_RS09090	COG0527	aspartate kinase activity
AEQSU_RS09090	COG0460	homoserine dehydrogenase
AEQSU_RS09095	COG1765	OsmC-like protein
AEQSU_RS09100	COG1410	methionine synthase
AEQSU_RS09100	COG0646	methionine synthase
AEQSU_RS09105	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AEQSU_RS09115	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AEQSU_RS09140	COG4555	ABC transporter
AEQSU_RS09150	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AEQSU_RS09155	COG1162	GTPase activity
AEQSU_RS09190	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AEQSU_RS09200	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AEQSU_RS09205	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AEQSU_RS09230	COG0358	DNA primase activity
AEQSU_RS09235	COG2197	response regulator
AEQSU_RS09240	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AEQSU_RS09255	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AEQSU_RS09265	COG2001	Belongs to the MraZ family
AEQSU_RS09270	COG0275	rRNA processing
AEQSU_RS09285	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AEQSU_RS09290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AEQSU_RS09295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AEQSU_RS09300	COG0772	Belongs to the SEDS family
AEQSU_RS09305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEQSU_RS09310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AEQSU_RS09325	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AEQSU_RS09330	COG1610	YqeY-like protein
AEQSU_RS09355	COG2003	Belongs to the UPF0758 family
AEQSU_RS09385	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AEQSU_RS09395	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEQSU_RS09410	COG4771	TonB-dependent receptor
AEQSU_RS09420	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AEQSU_RS09425	COG0049	tRNA binding
AEQSU_RS09430	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AEQSU_RS09435	COG0051	transcription antitermination factor activity, RNA binding
AEQSU_RS09440	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AEQSU_RS09445	COG0088	Forms part of the polypeptide exit tunnel
AEQSU_RS09450	COG0089	rRNA binding
AEQSU_RS09455	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AEQSU_RS09460	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AEQSU_RS09465	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AEQSU_RS09470	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AEQSU_RS09475	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AEQSU_RS09480	COG0255	Belongs to the universal ribosomal protein uL29 family
AEQSU_RS09485	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AEQSU_RS09490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AEQSU_RS09495	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AEQSU_RS09500	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AEQSU_RS09505	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AEQSU_RS09510	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AEQSU_RS09515	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AEQSU_RS09525	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AEQSU_RS09530	COG1841	ribosomal large subunit assembly
AEQSU_RS09535	COG0200	Binds to the 23S rRNA
AEQSU_RS09540	COG0201	protein transport
AEQSU_RS09545	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AEQSU_RS09550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AEQSU_RS09555	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AEQSU_RS09560	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AEQSU_RS09565	COG0202	RNA polymerase activity
AEQSU_RS09570	COG0203	ribosomal protein L17
AEQSU_RS09580	COG0148	phosphopyruvate hydratase activity
AEQSU_RS09595	COG1506	peptidase
AEQSU_RS09595	COG0823	Involved in the tonB-independent uptake of proteins
AEQSU_RS09600	COG3104	oligopeptide transport
AEQSU_RS09615	COG2333	competence protein COMEC
AEQSU_RS09615	COG0658	competence protein
AEQSU_RS09630	COG0791	NLP P60 protein
AEQSU_RS09635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AEQSU_RS09640	COG1181	Belongs to the D-alanine--D-alanine ligase family
AEQSU_RS09650	COG0564	pseudouridine synthase activity
AEQSU_RS09675	COG3591	Belongs to the peptidase S1B family
AEQSU_RS09680	COG0596	Alpha beta hydrolase
AEQSU_RS09685	COG2197	response regulator
AEQSU_RS09695	COG0596	Alpha beta hydrolase
AEQSU_RS09700	COG0477	Major facilitator Superfamily
AEQSU_RS09705	COG2354	Protein conserved in bacteria
AEQSU_RS09720	COG0488	(ABC) transporter
AEQSU_RS09750	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS09770	COG3263	regulation of cellular component size
AEQSU_RS09785	COG3022	response to hydroperoxide
AEQSU_RS09810	COG3420	alginic acid biosynthetic process
AEQSU_RS09815	COG0339	signal peptide processing
AEQSU_RS09820	COG4717	serine-type aminopeptidase activity
AEQSU_RS09825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AEQSU_RS09850	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AEQSU_RS09855	COG1115	amino acid carrier protein
AEQSU_RS09860	COG1115	amino acid carrier protein
AEQSU_RS09865	COG1596	polysaccharide export
AEQSU_RS09865	COG1555	photosystem II stabilization
AEQSU_RS09870	COG1960	acyl-CoA dehydrogenase activity
AEQSU_RS09880	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AEQSU_RS09885	COG4974	Belongs to the 'phage' integrase family
AEQSU_RS09890	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
AEQSU_RS09915	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AEQSU_RS09925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AEQSU_RS09935	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AEQSU_RS09940	COG0081	regulation of translation
AEQSU_RS09945	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AEQSU_RS09950	COG0222	ribosome binding
AEQSU_RS09955	COG0085	RNA polymerase activity
AEQSU_RS09960	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AEQSU_RS09970	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AEQSU_RS09985	COG2885	chlorophyll binding
AEQSU_RS09990	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AEQSU_RS10000	COG1482	cell wall glycoprotein biosynthetic process
AEQSU_RS10020	COG0596	Alpha beta hydrolase
AEQSU_RS10040	COG0300	oxidoreductase activity
AEQSU_RS10065	COG4452	Inner membrane protein CreD
AEQSU_RS10085	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AEQSU_RS10105	COG1217	gtp-binding protein TYPA
AEQSU_RS10160	COG0438	transferase activity, transferring glycosyl groups
AEQSU_RS10170	COG1216	Glycosyl transferase, family 2
AEQSU_RS10170	COG0463	Glycosyl transferase, family 2
AEQSU_RS10190	COG2884	Cell division ATP-binding protein ftsE
AEQSU_RS10205	COG1943	Transposase
AEQSU_RS10220	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AEQSU_RS10230	COG3876	Protein conserved in bacteria
AEQSU_RS10235	COG0577	efflux transmembrane transporter activity
AEQSU_RS10275	COG0326	Molecular chaperone. Has ATPase activity
AEQSU_RS10285	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AEQSU_RS10290	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AEQSU_RS10300	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEQSU_RS10310	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AEQSU_RS10320	COG0508	dehydrogenase complex catalyzes the overall conversion of
AEQSU_RS10325	COG5002	protein histidine kinase activity
AEQSU_RS10325	COG2176	DNA-directed DNA polymerase activity
AEQSU_RS10330	COG0179	Fumarylacetoacetate (FAA) hydrolase
AEQSU_RS10340	COG1546	Belongs to the CinA family
AEQSU_RS10340	COG1058	Belongs to the CinA family
AEQSU_RS10345	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AEQSU_RS10350	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AEQSU_RS10355	COG0552	protein localization to endoplasmic reticulum
AEQSU_RS10360	COG0823	Involved in the tonB-independent uptake of proteins
AEQSU_RS10360	COG1506	peptidase
AEQSU_RS10375	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQSU_RS10425	COG3279	Response regulator of the LytR AlgR family
AEQSU_RS10475	COG0671	phosphoesterase, PA-phosphatase related
AEQSU_RS10480	COG0534	Mate efflux family protein
AEQSU_RS10510	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
AEQSU_RS10525	COG1132	(ABC) transporter
AEQSU_RS10555	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQSU_RS10565	COG0386	Belongs to the glutathione peroxidase family
AEQSU_RS10570	COG0302	gtp cyclohydrolase
AEQSU_RS10620	COG1704	LemA family
AEQSU_RS10645	COG0579	oxidoreductase
AEQSU_RS10650	COG0492	ferredoxin-NADP+ reductase activity
AEQSU_RS10710	COG0714	Associated with various cellular activities
AEQSU_RS10745	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEQSU_RS10785	COG3655	Transcriptional regulator
AEQSU_RS10800	COG3275	phosphorelay sensor kinase activity
AEQSU_RS10820	COG2154	pterin-4-alpha-carbinolamine dehydratase
AEQSU_RS10830	COG2066	Belongs to the glutaminase family
AEQSU_RS10835	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AEQSU_RS10840	COG1012	belongs to the aldehyde dehydrogenase family
AEQSU_RS10850	COG0671	phosphoesterase, PA-phosphatase related
AEQSU_RS10865	COG0463	Glycosyl transferase, family 2
AEQSU_RS10870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AEQSU_RS10880	COG1368	sulfuric ester hydrolase activity
AEQSU_RS10895	COG1764	response to oxidative stress
AEQSU_RS10940	COG0653	protein targeting
AEQSU_RS10955	COG1136	(ABC) transporter
AEQSU_RS10965	COG0488	(ABC) transporter
AEQSU_RS10985	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
AEQSU_RS11040	COG1216	Glycosyl transferase, family 2
AEQSU_RS11040	COG0463	Glycosyl transferase, family 2
AEQSU_RS11060	COG0438	transferase activity, transferring glycosyl groups
AEQSU_RS11070	COG0438	transferase activity, transferring glycosyl groups
AEQSU_RS11085	COG2852	Protein conserved in bacteria
AEQSU_RS11145	COG0438	transferase activity, transferring glycosyl groups
AEQSU_RS11150	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEQSU_RS11170	COG1137	ATPase activity
AEQSU_RS11175	COG0805	protein transport
AEQSU_RS11180	COG0517	IMP dehydrogenase activity
AEQSU_RS11180	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AEQSU_RS11185	COG0514	ATP-dependent DNA helicase (RecQ)
AEQSU_RS11205	COG1612	heme a metabolic process
AEQSU_RS11210	COG0517	IMP dehydrogenase activity
AEQSU_RS11210	COG0617	tRNA 3'-terminal CCA addition
AEQSU_RS11210	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AEQSU_RS11215	COG0009	L-threonylcarbamoyladenylate synthase
AEQSU_RS11225	COG1442	glycosyl transferase family 8
AEQSU_RS11225	COG1216	Glycosyl transferase, family 2
AEQSU_RS11240	COG1215	transferase activity, transferring glycosyl groups
AEQSU_RS11245	COG0463	Glycosyl transferase, family 2
AEQSU_RS11250	COG0726	polysaccharide deacetylase
AEQSU_RS11255	COG0463	Glycosyl transferase, family 2
AEQSU_RS11260	COG1216	Glycosyl transferase, family 2
AEQSU_RS11265	COG1216	Glycosyl transferase, family 2
AEQSU_RS11265	COG0463	Glycosyl transferase, family 2
AEQSU_RS11285	COG2171	N-acyltransferase activity
AEQSU_RS11290	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AEQSU_RS11295	COG0242	peptide deformylase activity
AEQSU_RS11305	COG3956	TIGRFAM MazG family protein
AEQSU_RS11315	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AEQSU_RS11335	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEQSU_RS11345	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AEQSU_RS11355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AEQSU_RS11370	COG3547	Transposase (IS116 IS110 IS902 family)
AEQSU_RS11490	COG4974	Belongs to the 'phage' integrase family
AEQSU_RS11535	COG2234	aminopeptidase activity
AEQSU_RS11545	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AEQSU_RS11560	COG0308	aminopeptidase N
AEQSU_RS11580	COG4585	Histidine kinase
AEQSU_RS11600	COG0069	glutamate synthase activity
AEQSU_RS11615	COG0009	L-threonylcarbamoyladenylate synthase
AEQSU_RS11655	COG1575	Belongs to the MenA family. Type 1 subfamily
AEQSU_RS11660	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AEQSU_RS11690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AEQSU_RS11700	COG0488	(ABC) transporter
AEQSU_RS11710	COG0604	alcohol dehydrogenase
AEQSU_RS11710	COG3321	synthase
AEQSU_RS11710	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS11725	COG0010	Belongs to the arginase family
AEQSU_RS11730	COG1228	amidohydrolase
AEQSU_RS11750	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AEQSU_RS11755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AEQSU_RS11765	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AEQSU_RS11785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AEQSU_RS11805	COG4628	conserved protein (DUF2132)
AEQSU_RS11820	COG0513	Belongs to the DEAD box helicase family
AEQSU_RS11825	COG1234	tRNA 3'-trailer cleavage
AEQSU_RS11830	COG0259	pyridoxamine-phosphate oxidase activity
AEQSU_RS11840	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AEQSU_RS11860	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AEQSU_RS11870	COG1295	ribonuclease BN
AEQSU_RS11880	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AEQSU_RS11885	COG3279	Response regulator of the LytR AlgR family
AEQSU_RS11890	COG0360	Binds together with S18 to 16S ribosomal RNA
AEQSU_RS11895	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AEQSU_RS11900	COG0359	binds to the 23S rRNA
AEQSU_RS11910	COG0577	efflux transmembrane transporter activity
AEQSU_RS11915	COG0124	histidyl-tRNA synthetase
AEQSU_RS11940	COG1678	Uncharacterized ACR, COG1678
AEQSU_RS11950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AEQSU_RS11955	COG0514	ATP-dependent DNA helicase (RecQ)
AEQSU_RS11975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AEQSU_RS11990	COG0415	Belongs to the DNA photolyase family
AEQSU_RS11995	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS12055	COG1132	(ABC) transporter
AEQSU_RS12060	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AEQSU_RS12075	COG0254	rRNA binding
AEQSU_RS12095	COG2814	Major facilitator Superfamily
AEQSU_RS12110	COG1309	transcriptional regulator
AEQSU_RS12115	COG4166	transmembrane transport
AEQSU_RS12135	COG0542	response to heat
AEQSU_RS12160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AEQSU_RS12170	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AEQSU_RS12175	COG2226	methyltransferase
AEQSU_RS12175	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AEQSU_RS12175	COG0596	Alpha beta hydrolase
AEQSU_RS12180	COG0590	tRNA wobble adenosine to inosine editing
AEQSU_RS12195	COG4206	TonB-dependent receptor
AEQSU_RS12195	COG1629	transport
AEQSU_RS12210	COG0300	oxidoreductase activity
AEQSU_RS12220	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AEQSU_RS12230	COG0488	(ABC) transporter
AEQSU_RS12260	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AEQSU_RS12280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AEQSU_RS12320	COG2195	Cleaves the N-terminal amino acid of tripeptides
AEQSU_RS12325	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AEQSU_RS12335	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
AEQSU_RS12340	COG0105	UTP biosynthetic process
AEQSU_RS12355	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AEQSU_RS12365	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AEQSU_RS12375	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AEQSU_RS12400	COG0572	uridine kinase
AEQSU_RS12410	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AEQSU_RS12420	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AEQSU_RS12420	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AEQSU_RS12440	COG0038	chloride channel
AEQSU_RS12450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AEQSU_RS12470	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AEQSU_RS12480	COG1454	alcohol dehydrogenase
AEQSU_RS12490	COG0217	transcriptional regulatory protein
AEQSU_RS12495	COG3279	Response regulator of the LytR AlgR family
AEQSU_RS12540	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AEQSU_RS12555	COG0037	tRNA processing
AEQSU_RS12565	COG0205	6-phosphofructokinase activity
AEQSU_RS12580	COG0166	Belongs to the GPI family
AEQSU_RS12585	COG0606	chelatase, subunit chli
AEQSU_RS12640	COG0606	chelatase, subunit chli
AEQSU_RS12685	COG0612	Peptidase, M16
AEQSU_RS12705	COG4585	Histidine kinase
AEQSU_RS12710	COG2197	response regulator
AEQSU_RS12715	COG0564	pseudouridine synthase activity
AEQSU_RS12720	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AEQSU_RS12730	COG1760	l-serine dehydratase
AEQSU_RS12735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEQSU_RS12755	COG0443	Heat shock 70 kDa protein
AEQSU_RS12775	COG2050	protein possibly involved in aromatic compounds catabolism
AEQSU_RS12780	COG1169	isochorismate synthase
AEQSU_RS12785	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
AEQSU_RS12795	COG2996	Protein conserved in bacteria
AEQSU_RS12845	COG0367	asparagine synthase
AEQSU_RS12855	COG0513	Belongs to the DEAD box helicase family
AEQSU_RS12860	COG0484	heat shock protein binding
AEQSU_RS12880	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AEQSU_RS12885	COG1104	cysteine desulfurase activity
AEQSU_RS12910	COG1418	mRNA catabolic process
AEQSU_RS12915	COG0656	L-ascorbic acid biosynthetic process
AEQSU_RS12920	COG4974	Belongs to the 'phage' integrase family
AEQSU_RS12955	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AEQSU_RS12960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AEQSU_RS12965	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEQSU_RS12970	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEQSU_RS12985	COG2270	Major facilitator Superfamily
AEQSU_RS13000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AEQSU_RS13010	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AEQSU_RS13035	COG1522	sequence-specific DNA binding
AEQSU_RS13050	COG0693	protein deglycase activity
AEQSU_RS13060	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AEQSU_RS13085	COG2204	response regulator
AEQSU_RS13090	COG1078	dGTPase activity
AEQSU_RS13095	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AEQSU_RS13100	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AEQSU_RS13100	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEQSU_RS13105	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AEQSU_RS13110	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AEQSU_RS13115	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AEQSU_RS13125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AEQSU_RS13130	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS13165	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEQSU_RS13170	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AEQSU_RS13175	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AEQSU_RS13180	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AEQSU_RS13185	COG0131	Imidazoleglycerol-phosphate dehydratase
AEQSU_RS13185	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AEQSU_RS13190	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AEQSU_RS13195	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AEQSU_RS13200	COG0107	imidazoleglycerol-phosphate synthase activity
AEQSU_RS13205	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AEQSU_RS13205	COG0140	phosphoribosyl-ATP diphosphatase activity
AEQSU_RS13210	COG0598	Magnesium transport protein CorA
AEQSU_RS13215	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEQSU_RS13220	COG2169	Transcriptional regulator
AEQSU_RS13220	COG1917	Cupin 2, conserved barrel domain protein
AEQSU_RS13225	COG0277	FAD linked oxidase domain protein
AEQSU_RS13265	COG1278	Cold shock
AEQSU_RS13270	COG0352	thiamine-phosphate diphosphorylase activity
AEQSU_RS13295	COG4181	ATPase activity
AEQSU_RS13300	COG1136	(ABC) transporter
AEQSU_RS13300	COG0577	efflux transmembrane transporter activity
AEQSU_RS13310	COG1979	alcohol dehydrogenase
AEQSU_RS13315	COG1309	transcriptional regulator
AEQSU_RS13345	COG2116	formate transmembrane transporter activity
AEQSU_RS13355	COG0778	Nitroreductase
AEQSU_RS13380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AEQSU_RS13385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AEQSU_RS13390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AEQSU_RS13395	COG1028	Short-chain dehydrogenase reductase Sdr
AEQSU_RS13410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEQSU_RS13430	COG0022	dehydrogenase e1 component
AEQSU_RS13455	COG0813	purine-nucleoside phosphorylase activity
AEQSU_RS13465	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AEQSU_RS13475	COG3011	Protein conserved in bacteria
AEQSU_RS13480	COG1629	transport
AEQSU_RS13490	COG1301	dicarboxylic acid transport
AEQSU_RS13495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AEQSU_RS13500	COG2072	flavoprotein involved in K transport
AEQSU_RS13505	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AEQSU_RS13520	COG3708	Transcriptional regulator
AEQSU_RS13525	COG0277	FAD linked oxidase domain protein
AEQSU_RS13525	COG0247	lactate metabolic process
AEQSU_RS13540	COG0438	transferase activity, transferring glycosyl groups
AEQSU_RS13545	COG1472	Belongs to the glycosyl hydrolase 3 family
AEQSU_RS13555	COG2181	nitrate reductase activity
AEQSU_RS13555	COG0247	lactate metabolic process
AEQSU_RS13565	COG0247	lactate metabolic process
AEQSU_RS13565	COG2181	nitrate reductase activity
AEQSU_RS13570	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AEQSU_RS13575	COG0860	N-Acetylmuramoyl-L-alanine amidase
AEQSU_RS13585	COG0251	oxidation-reduction process
AEQSU_RS13615	COG2197	response regulator
AEQSU_RS13630	COG0697	spore germination
AEQSU_RS13650	COG0540	Belongs to the ATCase OTCase family
AEQSU_RS13655	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AEQSU_RS13685	COG0484	heat shock protein binding
AEQSU_RS13700	COG0012	GTP binding
AEQSU_RS13730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AEQSU_RS13740	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AEQSU_RS13745	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AEQSU_RS13770	COG4771	TonB-dependent receptor
AEQSU_RS13780	COG0302	gtp cyclohydrolase
AEQSU_RS13785	COG1136	(ABC) transporter
AEQSU_RS13805	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
AEQSU_RS13830	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AEQSU_RS13830	COG0321	lipoyl(octanoyl) transferase activity
AEQSU_RS13840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AEQSU_RS13845	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AEQSU_RS13855	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AEQSU_RS13885	COG0456	acetyltransferase
AEQSU_RS13895	COG0156	8-amino-7-oxononanoate synthase activity
AEQSU_RS13910	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AEQSU_RS13925	COG0022	dehydrogenase e1 component
AEQSU_RS13935	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AEQSU_RS13960	COG0628	permease
AEQSU_RS14000	COG3002	Belongs to the UPF0753 family
AEQSU_RS14005	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AEQSU_RS14015	COG0183	Belongs to the thiolase family
AEQSU_RS14020	COG0791	NLP P60 protein
AEQSU_RS14035	COG0542	response to heat
AEQSU_RS14050	COG2986	histidine ammonia-lyase
AEQSU_RS14055	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQSU_RS14075	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AEQSU_RS14080	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AEQSU_RS14095	COG0116	Belongs to the methyltransferase superfamily
AEQSU_RS14095	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AEQSU_RS14100	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AEQSU_RS14110	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AEQSU_RS14145	COG1363	Peptidase, m42
AEQSU_RS14150	COG1115	amino acid carrier protein
AEQSU_RS14175	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AEQSU_RS14180	COG1702	phosphate starvation-inducible protein PhoH
AEQSU_RS14205	COG0592	DNA-directed DNA polymerase activity
AEQSU_RS14225	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AEQSU_RS14235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEQSU_RS14245	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AEQSU_RS14260	COG3264	Mechanosensitive ion channel
AEQSU_RS14260	COG1196	nuclear chromosome segregation
AEQSU_RS14265	COG1012	belongs to the aldehyde dehydrogenase family
AEQSU_RS14285	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AEQSU_RS14290	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AEQSU_RS14310	COG1047	Peptidyl-prolyl cis-trans
AEQSU_RS14315	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AEQSU_RS14330	COG0095	Lipoate-protein ligase
AEQSU_RS14340	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
AEQSU_RS14360	COG1086	Polysaccharide biosynthesis protein
AEQSU_RS14365	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AEQSU_RS14380	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AEQSU_RS14410	COG0367	asparagine synthase
AEQSU_RS14420	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AEQSU_RS14425	COG0110	maltose O-acetyltransferase activity
AEQSU_RS14440	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AEQSU_RS14445	COG2089	acid synthase
AEQSU_RS14450	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
AEQSU_RS14455	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AEQSU_RS14485	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AEQSU_RS14495	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AEQSU_RS14515	COG0175	sulfate reduction
AEQSU_RS14525	COG0529	Catalyzes the synthesis of activated sulfate
AEQSU_RS14545	COG0783	Belongs to the Dps family
AEQSU_RS14570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQSU_RS14580	COG0705	Rhomboid family
AEQSU_RS14600	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AEQSU_RS14605	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
AEQSU_RS14610	COG0405	Gamma-glutamyltransferase
AEQSU_RS14620	COG1611	Belongs to the LOG family
AEQSU_RS14640	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AEQSU_RS14655	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AEQSU_RS14710	COG1393	Belongs to the ArsC family
AEQSU_RS14730	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AEQSU_RS14760	COG0424	maF-like protein
AEQSU_RS14770	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AEQSU_RS14795	COG1333	cytochrome c biogenesis protein
AEQSU_RS14795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AEQSU_RS14815	COG1595	DNA-templated transcription, initiation
AEQSU_RS14825	COG1607	acyl-coa hydrolase
AEQSU_RS14850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AEQSU_RS14895	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AEQSU_RS14925	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AEQSU_RS14935	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AEQSU_RS14935	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AEQSU_RS14950	COG0047	phosphoribosylformylglycinamidine synthase activity
AEQSU_RS14950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AEQSU_RS14955	COG1022	Amp-dependent synthetase and ligase
AEQSU_RS14965	COG2361	Protein of unknown function DUF86
AEQSU_RS14970	COG2076	Multidrug Resistance protein
AEQSU_RS14990	COG1846	Transcriptional regulator
AEQSU_RS14995	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEQSU_RS14995	COG1024	Enoyl-CoA hydratase
AEQSU_RS15000	COG0183	Belongs to the thiolase family
AEQSU_RS15005	COG1960	acyl-CoA dehydrogenase activity
AEQSU_RS15040	COG1132	(ABC) transporter
AEQSU_RS15045	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
AEQSU_RS15085	COG1597	lipid kinase activity
AEQSU_RS15125	COG1757	Na H antiporter
AEQSU_RS15130	COG0450	alkyl hydroperoxide reductase
AEQSU_RS15145	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AEQSU_RS15160	COG1674	ftsk spoiiie
AEQSU_RS15175	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEQSU_RS15175	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AEQSU_RS15185	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AEQSU_RS15195	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS15195	COG2205	protein histidine kinase activity
AEQSU_RS15195	COG3292	Two component regulator propeller
AEQSU_RS15235	COG4585	Histidine kinase
AEQSU_RS15255	COG0823	Involved in the tonB-independent uptake of proteins
AEQSU_RS15255	COG1506	peptidase
AEQSU_RS15265	COG4771	TonB-dependent receptor
AEQSU_RS15370	COG3237	CsbD-like
AEQSU_RS15400	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AEQSU_RS15405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AEQSU_RS15430	COG0322	excinuclease ABC activity
AEQSU_RS15435	COG0210	DNA helicase
AEQSU_RS15455	COG3665	Urea carboxylase-associated protein
AEQSU_RS15480	COG0415	Belongs to the DNA photolyase family
AEQSU_RS15490	COG3685	Protein conserved in bacteria
AEQSU_RS15495	COG2207	Transcriptional regulator
AEQSU_RS15510	COG0666	response to abiotic stimulus
AEQSU_RS15525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AEQSU_RS15585	COG3279	Response regulator of the LytR AlgR family
AEQSU_RS15605	COG1595	DNA-templated transcription, initiation
AEQSU_RS15640	COG1595	DNA-templated transcription, initiation
AEQSU_RS15680	COG0701	Predicted permease
AEQSU_RS15700	COG2132	Multicopper oxidase
AEQSU_RS15720	COG2194	sulfuric ester hydrolase activity
AEQSU_RS15740	COG5002	protein histidine kinase activity
AEQSU_RS15745	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS15755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AEQSU_RS15795	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AEQSU_RS15805	COG3237	CsbD-like
AEQSU_RS15815	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AEQSU_RS15835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AEQSU_RS15840	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AEQSU_RS15850	COG1250	3-hydroxyacyl-CoA dehydrogenase
AEQSU_RS15860	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AEQSU_RS15870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AEQSU_RS15875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AEQSU_RS15925	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AEQSU_RS15930	COG0497	DNA recombination
AEQSU_RS15955	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AEQSU_RS15975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AEQSU_RS15980	COG1611	Belongs to the LOG family
AEQSU_RS15985	COG2890	protein-(glutamine-N5) methyltransferase activity
AEQSU_RS15990	COG0456	acetyltransferase
AEQSU_RS15995	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEQSU_RS15995	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AEQSU_RS16000	COG0697	spore germination
AEQSU_RS16005	COG1739	Uncharacterized protein family UPF0029
AEQSU_RS16010	COG0824	Thioesterase
AEQSU_RS16030	COG0515	serine threonine protein kinase
AEQSU_RS16030	COG2815	serine threonine protein kinase
AEQSU_RS16060	COG2972	Histidine kinase
AEQSU_RS16100	COG1566	PFAM secretion protein HlyD family protein
AEQSU_RS16120	COG2226	methyltransferase
AEQSU_RS16130	COG3548	integral membrane protein
AEQSU_RS16180	COG0745	RESPONSE REGULATOR receiver
AEQSU_RS16180	COG2205	protein histidine kinase activity
AEQSU_RS16180	COG3292	Two component regulator propeller
AEQSU_RS16190	COG4585	Histidine kinase
AEQSU_RS16215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AEQSU_RS16250	COG2319	Wd-40 repeat
AEQSU_RS16250	COG4249	Peptidase C14 caspase catalytic subunit p20
AEQSU_RS16305	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AEQSU_RS16310	COG1680	COG1680 Beta-lactamase class C and other penicillin binding