locus-tag	class	description
IMX20_RS00010	COG0592	DNA-directed DNA polymerase activity
IMX20_RS00015	COG2501	S4 domain
IMX20_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
IMX20_RS00025	COG0187	DNA topoisomerase II activity
IMX20_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMX20_RS00035	COG0360	Binds together with S18 to 16S ribosomal RNA
IMX20_RS00040	COG0629	single-stranded DNA binding
IMX20_RS00045	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IMX20_RS00050	COG0346	lactoylglutathione lyase activity
IMX20_RS00055	COG0371	Dehydrogenase
IMX20_RS00060	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX20_RS00070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX20_RS00075	COG0601	transmembrane transport
IMX20_RS00080	COG4608	Belongs to the ABC transporter superfamily
IMX20_RS00095	COG0359	binds to the 23S rRNA
IMX20_RS00100	COG0305	Participates in initiation and elongation during chromosome replication
IMX20_RS00115	COG2217	Heavy metal translocating P-type atpase
IMX20_RS00130	COG1122	ATPase activity
IMX20_RS00140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
IMX20_RS00150	COG0693	protein deglycase activity
IMX20_RS00155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX20_RS00160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS00160	COG2190	(PTS) system
IMX20_RS00160	COG1263	PTS System
IMX20_RS00165	COG1428	Deoxynucleoside kinase
IMX20_RS00180	COG0596	Alpha beta hydrolase
IMX20_RS00195	COG1346	cytolysis
IMX20_RS00200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX20_RS00210	COG1418	mRNA catabolic process
IMX20_RS00215	COG1428	Deoxynucleoside kinase
IMX20_RS00220	COG0602	queuosine metabolic process
IMX20_RS00225	COG1328	CTP reductase activity
IMX20_RS00240	COG2151	metal-sulfur cluster biosynthetic enzyme
IMX20_RS00245	COG2217	Heavy metal translocating P-type atpase
IMX20_RS00250	COG1461	Dihydroxyacetone kinase
IMX20_RS00255	COG2376	Dihydroxyacetone kinase
IMX20_RS00260	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
IMX20_RS00265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
IMX20_RS00270	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
IMX20_RS00275	COG0789	Transcriptional regulator
IMX20_RS00295	COG3715	PTS system
IMX20_RS00300	COG3716	PTS system mannose fructose sorbose family IID component
IMX20_RS00310	COG1482	cell wall glycoprotein biosynthetic process
IMX20_RS00315	COG2116	formate transmembrane transporter activity
IMX20_RS00325	COG1496	oxidoreductase activity
IMX20_RS00350	COG0756	dUTP diphosphatase activity
IMX20_RS00355	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
IMX20_RS00360	COG4956	integral membrane protein (PIN domain superfamily)
IMX20_RS00365	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IMX20_RS00380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX20_RS00390	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMX20_RS00395	COG2233	PERMEase
IMX20_RS00405	COG1174	glycine betaine transport
IMX20_RS00410	COG0517	IMP dehydrogenase activity
IMX20_RS00410	COG1125	glycine betaine transport
IMX20_RS00415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
IMX20_RS00430	COG2124	cytochrome p450
IMX20_RS00455	COG0456	acetyltransferase
IMX20_RS00485	COG2003	Belongs to the UPF0758 family
IMX20_RS00495	COG0488	(ABC) transporter
IMX20_RS00510	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMX20_RS00545	COG2217	Heavy metal translocating P-type atpase
IMX20_RS00550	COG0640	Transcriptional regulator
IMX20_RS00565	COG1307	EDD domain protein, DegV family
IMX20_RS00585	COG1523	belongs to the glycosyl hydrolase 13 family
IMX20_RS00620	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
IMX20_RS00625	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMX20_RS00630	COG3688	RNA-binding protein containing a PIN domain
IMX20_RS00645	COG2610	gluconate transmembrane transporter activity
IMX20_RS00650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMX20_RS00660	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
IMX20_RS00670	COG0250	Participates in transcription elongation, termination and antitermination
IMX20_RS00680	COG0704	Plays a role in the regulation of phosphate uptake
IMX20_RS00685	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IMX20_RS00690	COG0081	regulation of translation
IMX20_RS00700	COG0222	ribosome binding
IMX20_RS00710	COG1121	(ABC) transporter
IMX20_RS00715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMX20_RS00715	COG1321	iron dependent repressor
IMX20_RS00720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMX20_RS00725	COG2813	Specifically methylates the guanine in position
IMX20_RS00730	COG3448	diguanylate cyclase activity
IMX20_RS00730	COG4175	Glycine betaine
IMX20_RS00750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_RS00755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_RS00760	COG0135	phosphoribosylanthranilate isomerase activity
IMX20_RS00770	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMX20_RS00775	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_RS00785	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IMX20_RS00825	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IMX20_RS00835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IMX20_RS00840	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
IMX20_RS00845	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IMX20_RS00855	COG0470	DNA polymerase III
IMX20_RS00860	COG1396	sequence-specific DNA binding
IMX20_RS00870	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
IMX20_RS00870	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
IMX20_RS00880	COG4467	Involved in initiation control of chromosome replication
IMX20_RS00885	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
IMX20_RS00890	COG2827	Endonuclease containing a URI domain
IMX20_RS00895	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IMX20_RS00905	COG1970	mechanosensitive ion channel activity
IMX20_RS00910	COG2079	MmgE PrpD family protein
IMX20_RS00920	COG0372	Belongs to the citrate synthase family
IMX20_RS00925	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IMX20_RS00935	COG0436	Aminotransferase
IMX20_RS00940	COG2814	Major facilitator Superfamily
IMX20_RS00945	COG1078	dGTPase activity
IMX20_RS00950	COG0095	Lipoate-protein ligase
IMX20_RS00960	COG3343	RNA polymerase activity
IMX20_RS00965	COG0504	CTP synthase activity
IMX20_RS00975	COG0284	orotidine-5'-phosphate decarboxylase activity
IMX20_RS00985	COG2814	Major facilitator Superfamily
IMX20_RS00990	COG2832	Protein of unknown function (DUF454)
IMX20_RS01015	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMX20_RS01020	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IMX20_RS01025	COG0254	rRNA binding
IMX20_RS01035	COG0251	oxidation-reduction process
IMX20_RS01040	COG0456	acetyltransferase
IMX20_RS01045	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
IMX20_RS01055	COG3764	Sortase (surface protein transpeptidase)
IMX20_RS01070	COG1181	Belongs to the D-alanine--D-alanine ligase family
IMX20_RS01075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMX20_RS01085	COG0736	holo-[acyl-carrier-protein] synthase activity
IMX20_RS01095	COG1174	glycine betaine transport
IMX20_RS01110	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
IMX20_RS01115	COG4708	membrane
IMX20_RS01120	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMX20_RS01135	COG1253	flavin adenine dinucleotide binding
IMX20_RS01140	COG4122	O-methyltransferase activity
IMX20_RS01190	COG2326	polyphosphate kinase activity
IMX20_RS01195	COG0288	reversible hydration of carbon dioxide
IMX20_RS01200	COG4290	ribonuclease
IMX20_RS01205	COG2732	(Barnase) inhibitor
IMX20_RS01235	COG0322	excinuclease ABC activity
IMX20_RS01240	COG1408	metallophosphoesterase
IMX20_RS01245	COG0513	Belongs to the DEAD box helicase family
IMX20_RS01255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IMX20_RS01265	COG0039	L-malate dehydrogenase activity
IMX20_RS01270	COG0193	aminoacyl-tRNA hydrolase activity
IMX20_RS01275	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IMX20_RS01280	COG2244	polysaccharide biosynthetic process
IMX20_RS01285	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
IMX20_RS01295	COG1098	S1 RNA binding domain
IMX20_RS01300	COG0037	tRNA processing
IMX20_RS01305	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IMX20_RS01310	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMX20_RS01315	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IMX20_RS01325	COG0640	Transcriptional regulator
IMX20_RS01330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IMX20_RS01335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IMX20_RS01340	COG0049	tRNA binding
IMX20_RS01345	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IMX20_RS01350	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
IMX20_RS01370	COG0505	Belongs to the CarA family
IMX20_RS01375	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMX20_RS01400	COG0051	transcription antitermination factor activity, RNA binding
IMX20_RS01405	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IMX20_RS01410	COG0088	Forms part of the polypeptide exit tunnel
IMX20_RS01415	COG0089	rRNA binding
IMX20_RS01430	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IMX20_RS01435	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IMX20_RS01440	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IMX20_RS01445	COG0255	Belongs to the universal ribosomal protein uL29 family
IMX20_RS01450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IMX20_RS01455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IMX20_RS01460	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IMX20_RS01470	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMX20_RS01475	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IMX20_RS01480	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
IMX20_RS01485	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IMX20_RS01490	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IMX20_RS01495	COG1841	ribosomal large subunit assembly
IMX20_RS01510	COG0563	adenylate kinase activity
IMX20_RS01525	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IMX20_RS01530	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IMX20_RS01535	COG0202	RNA polymerase activity
IMX20_RS01540	COG0203	ribosomal protein L17
IMX20_RS01545	COG2755	lipolytic protein G-D-S-L family
IMX20_RS01545	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IMX20_RS01555	COG1122	ATPase activity
IMX20_RS01560	COG1122	ATPase activity
IMX20_RS01580	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
IMX20_RS01595	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMX20_RS01600	COG0583	DNA-binding transcription factor activity
IMX20_RS01605	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IMX20_RS01610	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IMX20_RS01620	COG2217	Heavy metal translocating P-type atpase
IMX20_RS01625	COG3759	membrane
IMX20_RS01635	COG0662	Cupin 2, conserved barrel domain protein
IMX20_RS01640	COG1942	4-Oxalocrotonate Tautomerase
IMX20_RS01670	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMX20_RS01670	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
IMX20_RS01710	COG1309	transcriptional regulator
IMX20_RS01715	COG0657	acetylesterase activity
IMX20_RS01720	COG2723	6-phospho-beta-galactosidase activity
IMX20_RS01730	COG1733	regulation of RNA biosynthetic process
IMX20_RS01740	COG3339	Conserved Protein
IMX20_RS01755	COG0352	thiamine-phosphate diphosphorylase activity
IMX20_RS01760	COG0351	phosphomethylpyrimidine kinase
IMX20_RS01770	COG1929	Belongs to the glycerate kinase type-1 family
IMX20_RS01805	COG1725	Transcriptional regulator
IMX20_RS01810	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IMX20_RS01815	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IMX20_RS01820	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IMX20_RS01825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IMX20_RS01830	COG0131	Imidazoleglycerol-phosphate dehydratase
IMX20_RS01835	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
IMX20_RS01840	COG0107	imidazoleglycerol-phosphate synthase activity
IMX20_RS01845	COG0140	phosphoribosyl-ATP diphosphatase activity
IMX20_RS01845	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IMX20_RS01850	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IMX20_RS01865	COG2188	Transcriptional regulator
IMX20_RS01870	COG0386	Belongs to the glutathione peroxidase family
IMX20_RS01905	COG0656	L-ascorbic acid biosynthetic process
IMX20_RS01930	COG0702	epimerase
IMX20_RS01935	COG4708	membrane
IMX20_RS01950	COG2217	Heavy metal translocating P-type atpase
IMX20_RS01960	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX20_RS01970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_RS01975	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IMX20_RS01980	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_RS01985	COG1126	abc transporter atp-binding protein
IMX20_RS01990	COG0765	amino acid transport
IMX20_RS01995	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX20_RS02000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_RS02005	COG4565	transcriptional regulatory protein
IMX20_RS02010	COG3290	protein histidine kinase activity
IMX20_RS02015	COG3493	citrate carrier protein
IMX20_RS02025	COG4166	transmembrane transport
IMX20_RS02035	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
IMX20_RS02060	COG2137	regulation of response to DNA damage stimulus
IMX20_RS02065	COG1194	a g-specific adenine glycosylase
IMX20_RS02070	COG3557	Belongs to the UPF0374 family
IMX20_RS02080	COG1523	belongs to the glycosyl hydrolase 13 family
IMX20_RS02085	COG4129	membrane
IMX20_RS02090	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IMX20_RS02100	COG0667	Aldo Keto reductase
IMX20_RS02210	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_RS02215	COG1464	Belongs to the NlpA lipoprotein family
IMX20_RS02220	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IMX20_RS02225	COG0406	alpha-ribazole phosphatase activity
IMX20_RS02230	COG2723	6-phospho-beta-galactosidase activity
IMX20_RS02235	COG2188	Transcriptional regulator
IMX20_RS02240	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_RS02255	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_RS02260	COG0667	Aldo Keto reductase
IMX20_RS02265	COG0561	phosphatase activity
IMX20_RS02275	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMX20_RS02280	COG1263	PTS System
IMX20_RS02280	COG2190	(PTS) system
IMX20_RS02280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS02285	COG2723	6-phospho-beta-galactosidase activity
IMX20_RS02305	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMX20_RS02310	COG2011	ABC-type metal ion transport system permease component
IMX20_RS02315	COG1464	Belongs to the NlpA lipoprotein family
IMX20_RS02320	COG0431	NADPH-dependent FMN reductase
IMX20_RS02330	COG0765	amino acid transport
IMX20_RS02335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX20_RS02340	COG0765	amino acid transport
IMX20_RS02345	COG1126	abc transporter atp-binding protein
IMX20_RS02350	COG0686	Belongs to the AlaDH PNT family
IMX20_RS02355	COG3949	Membrane
IMX20_RS02360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
IMX20_RS02370	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMX20_RS02375	COG3679	Belongs to the UPF0342 family
IMX20_RS02380	COG0420	3'-5' exonuclease activity
IMX20_RS02385	COG4717	serine-type aminopeptidase activity
IMX20_RS02400	COG0737	Belongs to the 5'-nucleotidase family
IMX20_RS02405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IMX20_RS02415	COG0537	adenosine 5'-monophosphoramidase activity
IMX20_RS02420	COG1131	(ABC) transporter
IMX20_RS02425	COG4473	ABC transporter
IMX20_RS02435	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IMX20_RS02445	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX20_RS02455	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IMX20_RS02470	COG1785	Belongs to the alkaline phosphatase family
IMX20_RS02495	COG1573	uracil-dna glycosylase
IMX20_RS02500	COG2270	Major facilitator Superfamily
IMX20_RS02520	COG0435	Glutathione S-transferase
IMX20_RS02530	COG0302	gtp cyclohydrolase
IMX20_RS02535	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
IMX20_RS02540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
IMX20_RS02545	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IMX20_RS02550	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
IMX20_RS02555	COG0406	alpha-ribazole phosphatase activity
IMX20_RS02560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX20_RS02570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMX20_RS02570	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IMX20_RS02575	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
IMX20_RS02580	COG0237	dephospho-CoA kinase activity
IMX20_RS02595	COG1484	DNA-dependent DNA replication
IMX20_RS02610	COG1302	Protein conserved in bacteria
IMX20_RS02615	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMX20_RS02625	COG2818	Glycosylase
IMX20_RS02630	COG1464	Belongs to the NlpA lipoprotein family
IMX20_RS02640	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IMX20_RS02650	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IMX20_RS02655	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMX20_RS02660	COG2011	ABC-type metal ion transport system permease component
IMX20_RS02665	COG1464	Belongs to the NlpA lipoprotein family
IMX20_RS02675	COG0095	Lipoate-protein ligase
IMX20_RS02680	COG4862	establishment of competence for transformation
IMX20_RS02685	COG1393	Belongs to the ArsC family
IMX20_RS02690	COG0180	Tryptophanyl-tRNA synthetase
IMX20_RS02705	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMX20_RS02715	COG2357	RelA SpoT domain protein
IMX20_RS02725	COG0564	pseudouridine synthase activity
IMX20_RS02730	COG2239	Acts as a magnesium transporter
IMX20_RS02740	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMX20_RS02745	COG0105	UTP biosynthetic process
IMX20_RS02750	COG0625	glutathione transferase activity
IMX20_RS02765	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IMX20_RS02770	COG0583	DNA-binding transcription factor activity
IMX20_RS02780	COG0542	response to heat
IMX20_RS02785	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX20_RS02795	COG0438	transferase activity, transferring glycosyl groups
IMX20_RS02800	COG4703	Protein of unknown function (DUF1797)
IMX20_RS02805	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
IMX20_RS02810	COG0460	homoserine dehydrogenase
IMX20_RS02815	COG0083	homoserine kinase activity
IMX20_RS02820	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
IMX20_RS02825	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
IMX20_RS02830	COG1534	Rna-binding protein
IMX20_RS02835	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IMX20_RS02840	COG1713	HD superfamily hydrolase involved in NAD metabolism
IMX20_RS02845	COG0799	negative regulation of ribosome biogenesis
IMX20_RS02850	COG2226	methyltransferase
IMX20_RS02855	COG1323	Belongs to the UPF0348 family
IMX20_RS02860	COG1399	metal-binding, possibly nucleic acid-binding protein
IMX20_RS02880	COG2001	Belongs to the MraZ family
IMX20_RS02895	COG0768	penicillin binding
IMX20_RS02900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IMX20_RS02905	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMX20_RS02910	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IMX20_RS02915	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IMX20_RS02920	COG0849	cell division
IMX20_RS02930	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IMX20_RS02945	COG2302	S4 RNA-binding domain
IMX20_RS02950	COG3599	regulation of cell shape
IMX20_RS02955	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IMX20_RS02965	COG2261	transglycosylase associated protein
IMX20_RS02970	COG3853	Toxic anion resistance protein (TelA)
IMX20_RS02980	COG0494	nUDIX hydrolase
IMX20_RS02995	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IMX20_RS03000	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
IMX20_RS03005	COG1104	cysteine desulfurase activity
IMX20_RS03010	COG0301	tRNA thio-modification
IMX20_RS03015	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
IMX20_RS03025	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
IMX20_RS03030	COG0745	RESPONSE REGULATOR receiver
IMX20_RS03045	COG0028	Belongs to the TPP enzyme family
IMX20_RS03050	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
IMX20_RS03055	COG0706	membrane insertase activity
IMX20_RS03060	COG1254	Belongs to the acylphosphatase family
IMX20_RS03070	COG1280	lysine exporter protein (LysE YggA)
IMX20_RS03070	COG1674	ftsk spoiiie
IMX20_RS03075	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IMX20_RS03085	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IMX20_RS03125	COG1914	H( )-stimulated, divalent metal cation uptake system
IMX20_RS03130	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IMX20_RS03135	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IMX20_RS03150	COG2255	four-way junction helicase activity
IMX20_RS03155	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IMX20_RS03160	COG0587	DNA-directed DNA polymerase activity
IMX20_RS03165	COG0205	6-phosphofructokinase activity
IMX20_RS03175	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IMX20_RS03185	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
IMX20_RS03190	COG2996	Protein conserved in bacteria
IMX20_RS03200	COG4152	abc transporter atp-binding protein
IMX20_RS03205	COG1668	transmembrane transport
IMX20_RS03210	COG0456	acetyltransferase
IMX20_RS03215	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IMX20_RS03220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IMX20_RS03225	COG1187	pseudouridine synthase activity
IMX20_RS03230	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
IMX20_RS03240	COG0514	ATP-dependent DNA helicase (RecQ)
IMX20_RS03250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
IMX20_RS03260	COG0539	negative regulation of cytoplasmic translation
IMX20_RS03265	COG1160	GTP binding
IMX20_RS03280	COG1621	beta-fructofuranosidase activity
IMX20_RS03285	COG1609	Transcriptional regulator
IMX20_RS03300	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
IMX20_RS03305	COG0617	tRNA 3'-terminal CCA addition
IMX20_RS03310	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IMX20_RS03310	COG1199	ATP-dependent helicase activity
IMX20_RS03330	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IMX20_RS03335	COG1846	Transcriptional regulator
IMX20_RS03340	COG0737	Belongs to the 5'-nucleotidase family
IMX20_RS03345	COG4470	Protein conserved in bacteria
IMX20_RS03350	COG0647	UMP catabolic process
IMX20_RS03360	COG0492	ferredoxin-NADP+ reductase activity
IMX20_RS03365	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
IMX20_RS03370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IMX20_RS03375	COG1098	S1 RNA binding domain
IMX20_RS03380	COG0166	Belongs to the GPI family
IMX20_RS03515	COG1792	Involved in formation and maintenance of cell shape
IMX20_RS03525	COG0765	amino acid transport
IMX20_RS03530	COG1126	abc transporter atp-binding protein
IMX20_RS03540	COG2868	ribosomal protein
IMX20_RS03560	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
IMX20_RS03570	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
IMX20_RS03575	COG1263	PTS System
IMX20_RS03575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS03580	COG1737	Transcriptional regulator
IMX20_RS03605	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IMX20_RS03615	COG1104	cysteine desulfurase activity
IMX20_RS03625	COG0482	sulfurtransferase activity
IMX20_RS03630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
IMX20_RS03635	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IMX20_RS03640	COG4472	Bacterial protein of unknown function (DUF965)
IMX20_RS03645	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
IMX20_RS03650	COG3906	Belongs to the UPF0473 family
IMX20_RS03660	COG1959	2 iron, 2 sulfur cluster binding
IMX20_RS03665	COG1511	domain protein
IMX20_RS03670	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IMX20_RS03680	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IMX20_RS03695	COG2197	response regulator
IMX20_RS03700	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
IMX20_RS03705	COG5503	Protein of unknown function (DUF1447)
IMX20_RS03710	COG4129	membrane
IMX20_RS03715	COG1272	protein, Hemolysin III
IMX20_RS03730	COG1307	EDD domain protein, DegV family
IMX20_RS03750	COG4619	ABC transporter
IMX20_RS03755	COG0390	transport system, permease component
IMX20_RS03765	COG1072	(Pantothenic acid kinase))
IMX20_RS03770	COG0628	permease
IMX20_RS03775	COG1132	(ABC) transporter
IMX20_RS03780	COG1132	(ABC) transporter
IMX20_RS03785	COG0488	(ABC) transporter
IMX20_RS03790	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
IMX20_RS03800	COG0561	phosphatase activity
IMX20_RS03805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IMX20_RS03810	COG3682	Transcriptional regulator
IMX20_RS03815	COG1780	Probably involved in ribonucleotide reductase function
IMX20_RS03820	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IMX20_RS03830	COG2267	carboxylic ester hydrolase activity
IMX20_RS03835	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMX20_RS03840	COG3331	DNA recombination
IMX20_RS03845	COG0544	peptidyl-prolyl cis-trans isomerase activity
IMX20_RS03850	COG1957	nucleoside hydrolase
IMX20_RS03855	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
IMX20_RS03860	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IMX20_RS03865	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IMX20_RS03870	COG0358	DNA primase activity
IMX20_RS03875	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IMX20_RS03885	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IMX20_RS03890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IMX20_RS03895	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IMX20_RS03900	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IMX20_RS03905	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IMX20_RS03910	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IMX20_RS03915	COG0488	(ABC) transporter
IMX20_RS03945	COG2384	SAM-dependent methyltransferase
IMX20_RS03950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
IMX20_RS03955	COG2195	Cleaves the N-terminal amino acid of tripeptides
IMX20_RS03960	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
IMX20_RS03965	COG1074	ATP-dependent DNA helicase activity
IMX20_RS03975	COG0328	RNA-DNA hybrid ribonuclease activity
IMX20_RS03975	COG3341	Caulimovirus viroplasmin
IMX20_RS03980	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
IMX20_RS03985	COG0564	pseudouridine synthase activity
IMX20_RS03990	COG3763	UPF0154 protein
IMX20_RS03995	COG1132	(ABC) transporter
IMX20_RS04000	COG1132	(ABC) transporter
IMX20_RS04005	COG0204	Acyl-transferase
IMX20_RS04010	COG0628	permease
IMX20_RS04020	COG0052	Belongs to the universal ribosomal protein uS2 family
IMX20_RS04025	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IMX20_RS04030	COG0528	UMP kinase activity
IMX20_RS04035	COG0233	cytoplasmic translational termination
IMX20_RS04040	COG5002	protein histidine kinase activity
IMX20_RS04045	COG0745	RESPONSE REGULATOR receiver
IMX20_RS04065	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IMX20_RS04070	COG4589	Belongs to the CDS family
IMX20_RS04075	COG0750	zinc metalloprotease
IMX20_RS04080	COG2176	DNA-directed DNA polymerase activity
IMX20_RS04095	COG0779	Required for maturation of 30S ribosomal subunits
IMX20_RS04100	COG0195	Participates in both transcription termination and antitermination
IMX20_RS04105	COG2740	Nucleic-acid-binding protein implicated in transcription termination
IMX20_RS04120	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IMX20_RS04130	COG3759	membrane
IMX20_RS04140	COG0740	serine-type endopeptidase activity
IMX20_RS04145	COG2390	Transcriptional regulator
IMX20_RS04160	COG0149	triose-phosphate isomerase activity
IMX20_RS04165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
IMX20_RS04170	COG0148	phosphopyruvate hydratase activity
IMX20_RS04185	COG4166	transmembrane transport
IMX20_RS04190	COG4166	transmembrane transport
IMX20_RS04200	COG0601	transmembrane transport
IMX20_RS04205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IMX20_RS04210	COG0444	Belongs to the ABC transporter superfamily
IMX20_RS04215	COG4608	Belongs to the ABC transporter superfamily
IMX20_RS04230	COG0557	exoribonuclease II activity
IMX20_RS04235	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IMX20_RS04245	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
IMX20_RS04250	COG0588	phosphoglycerate mutase activity
IMX20_RS04255	COG3949	Membrane
IMX20_RS04335	COG1715	Restriction endonuclease
IMX20_RS04400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IMX20_RS04410	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IMX20_RS04420	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IMX20_RS04425	COG0439	Biotin carboxylase
IMX20_RS04430	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IMX20_RS04465	COG0116	Belongs to the methyltransferase superfamily
IMX20_RS04475	COG3599	regulation of cell shape
IMX20_RS04490	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IMX20_RS04495	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IMX20_RS04500	COG1490	D-aminoacyl-tRNA deacylase activity
IMX20_RS04510	COG0124	histidyl-tRNA synthetase
IMX20_RS04515	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IMX20_RS04530	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
IMX20_RS04540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
IMX20_RS04545	COG0167	dihydroorotate dehydrogenase activity
IMX20_RS04550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
IMX20_RS04555	COG0346	lactoylglutathione lyase activity
IMX20_RS04560	COG0735	belongs to the Fur family
IMX20_RS04570	COG1610	YqeY-like protein
IMX20_RS04575	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_RS04590	COG1702	phosphate starvation-inducible protein PhoH
IMX20_RS04595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IMX20_RS04605	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IMX20_RS04610	COG1381	Involved in DNA repair and RecF pathway recombination
IMX20_RS04615	COG0752	glycyl-tRNA synthetase alpha subunit
IMX20_RS04620	COG0751	glycine-tRNA ligase activity
IMX20_RS04630	COG1234	tRNA 3'-trailer cleavage
IMX20_RS04635	COG4221	oxidoreductase activity
IMX20_RS04640	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
IMX20_RS04640	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IMX20_RS04645	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMX20_RS04655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IMX20_RS04670	COG1293	RNA-binding protein homologous to eukaryotic snRNP
IMX20_RS04680	COG4120	Belongs to the binding-protein-dependent transport system permease family
IMX20_RS04685	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
IMX20_RS04685	COG1116	anion transmembrane transporter activity
IMX20_RS04695	COG4166	transmembrane transport
IMX20_RS04700	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IMX20_RS04705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
IMX20_RS04710	COG0494	nUDIX hydrolase
IMX20_RS04715	COG1349	DNA-binding transcription factor activity
IMX20_RS04720	COG1105	Belongs to the carbohydrate kinase PfkB family
IMX20_RS04725	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX20_RS04725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX20_RS04725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
IMX20_RS04730	COG1132	(ABC) transporter
IMX20_RS04735	COG1132	(ABC) transporter
IMX20_RS04745	COG0456	acetyltransferase
IMX20_RS04755	COG1126	abc transporter atp-binding protein
IMX20_RS04765	COG1175	transmembrane transport
IMX20_RS04770	COG0395	ABC-type sugar transport system, permease component
IMX20_RS04780	COG3842	ATPase activity
IMX20_RS04785	COG0366	Alpha amylase catalytic
IMX20_RS04790	COG1609	Transcriptional regulator
IMX20_RS04795	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMX20_RS04800	COG4468	UDPglucose--hexose-1-phosphate uridylyltransferase
IMX20_RS04820	COG2211	Major facilitator Superfamily
IMX20_RS04835	COG2086	electron transfer activity
IMX20_RS04840	COG1960	acyl-CoA dehydrogenase activity
IMX20_RS04860	COG1301	dicarboxylic acid transport
IMX20_RS04870	COG4974	Belongs to the 'phage' integrase family
IMX20_RS04880	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
IMX20_RS04885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IMX20_RS04895	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMX20_RS04900	COG0569	domain protein
IMX20_RS04905	COG1227	inorganic diphosphatase activity
IMX20_RS04915	COG0183	Belongs to the thiolase family
IMX20_RS04920	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
IMX20_RS04925	COG0187	DNA topoisomerase II activity
IMX20_RS04940	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
IMX20_RS04945	COG0758	DNA mediated transformation
IMX20_RS04950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IMX20_RS04965	COG0793	Belongs to the peptidase S41A family
IMX20_RS04965	COG3409	Peptidoglycan-binding domain 1 protein
IMX20_RS04990	COG0488	(ABC) transporter
IMX20_RS05000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IMX20_RS05005	COG0717	Belongs to the dCTP deaminase family
IMX20_RS05025	COG0656	L-ascorbic acid biosynthetic process
IMX20_RS05045	COG0484	heat shock protein binding
IMX20_RS05050	COG0443	Heat shock 70 kDa protein
IMX20_RS05055	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IMX20_RS05060	COG1420	regulation of RNA biosynthetic process
IMX20_RS05065	COG1473	amidohydrolase
IMX20_RS05070	COG0196	riboflavin kinase activity
IMX20_RS05075	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IMX20_RS05085	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IMX20_RS05090	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IMX20_RS05100	COG0009	L-threonylcarbamoyladenylate synthase
IMX20_RS05105	COG2890	protein-(glutamine-N5) methyltransferase activity
IMX20_RS05110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IMX20_RS05115	COG1435	thymidine kinase activity
IMX20_RS05120	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
IMX20_RS05125	COG3442	glutamine amidotransferase
IMX20_RS05140	COG1132	(ABC) transporter
IMX20_RS05145	COG0628	permease
IMX20_RS05150	COG2706	6-phosphogluconolactonase activity
IMX20_RS05155	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IMX20_RS05160	COG1079	Belongs to the binding-protein-dependent transport system permease family
IMX20_RS05165	COG4603	Belongs to the binding-protein-dependent transport system permease family
IMX20_RS05170	COG3845	ABC transporter
IMX20_RS05175	COG1744	ABC transporter substrate-binding protein PnrA-like
IMX20_RS05180	COG2190	(PTS) system
IMX20_RS05180	COG1263	PTS System
IMX20_RS05180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS05185	COG1968	undecaprenyl-diphosphatase activity
IMX20_RS05190	COG0527	aspartate kinase activity
IMX20_RS05195	COG0297	glycogen (starch) synthase activity
IMX20_RS05200	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMX20_RS05205	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMX20_RS05220	COG0346	lactoylglutathione lyase activity
IMX20_RS05240	COG0517	IMP dehydrogenase activity
IMX20_RS05245	COG0683	leucine binding
IMX20_RS05250	COG2183	response to ionizing radiation
IMX20_RS05270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IMX20_RS05290	COG0018	arginyl-trna synthetase
IMX20_RS05300	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IMX20_RS05310	COG1136	(ABC) transporter
IMX20_RS05310	COG0577	efflux transmembrane transporter activity
IMX20_RS05320	COG0509	glycine decarboxylation via glycine cleavage system
IMX20_RS05325	COG0772	Belongs to the SEDS family
IMX20_RS05330	COG1295	ribonuclease BN
IMX20_RS05345	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IMX20_RS05350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IMX20_RS05355	COG0497	DNA recombination
IMX20_RS05360	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
IMX20_RS05370	COG1722	exodeoxyribonuclease VII activity
IMX20_RS05375	COG1570	exodeoxyribonuclease VII activity
IMX20_RS05380	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IMX20_RS05385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMX20_RS05395	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IMX20_RS05400	COG0006	proline dipeptidase activity
IMX20_RS05425	COG4537	Required for transformation and DNA binding
IMX20_RS05430	COG1459	type II secretion system
IMX20_RS05435	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
IMX20_RS05450	COG1269	ATP hydrolysis coupled proton transport
IMX20_RS05480	COG1394	ATPase activity, coupled to movement of substances
IMX20_RS05485	COG0217	transcriptional regulatory protein
IMX20_RS05490	COG1597	lipid kinase activity
IMX20_RS05495	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
IMX20_RS05500	COG1063	alcohol dehydrogenase
IMX20_RS05505	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
IMX20_RS05510	COG0656	L-ascorbic acid biosynthetic process
IMX20_RS05520	COG3830	Belongs to the UPF0237 family
IMX20_RS05525	COG2843	Capsule synthesis protein
IMX20_RS05545	COG0668	transmembrane transport
IMX20_RS05550	COG0622	Phosphoesterase
IMX20_RS05555	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IMX20_RS05570	COG3118	belongs to the thioredoxin family
IMX20_RS05575	COG1193	negative regulation of DNA recombination
IMX20_RS05590	COG0765	amino acid transport
IMX20_RS05640	COG0179	Fumarylacetoacetate (FAA) hydrolase
IMX20_RS05645	COG1720	tRNA m6t6A37 methyltransferase activity
IMX20_RS05655	COG2176	DNA-directed DNA polymerase activity
IMX20_RS05660	COG1671	Belongs to the UPF0178 family
IMX20_RS05670	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMX20_RS05675	COG0765	amino acid transport
IMX20_RS05680	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
IMX20_RS05690	COG0561	phosphatase activity
IMX20_RS05705	COG1737	Transcriptional regulator
IMX20_RS05710	COG0673	inositol 2-dehydrogenase activity
IMX20_RS05715	COG0673	inositol 2-dehydrogenase activity
IMX20_RS05720	COG0584	glycerophosphoryl diester phosphodiesterase
IMX20_RS05735	COG1175	transmembrane transport
IMX20_RS05755	COG0083	homoserine kinase activity
IMX20_RS05770	COG1304	FMN binding
IMX20_RS05780	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
IMX20_RS05785	COG1122	ATPase activity
IMX20_RS05790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IMX20_RS05805	COG0802	atpase or kinase
IMX20_RS05810	COG0280	phosphate acetyltransferase
IMX20_RS05815	COG1070	Carbohydrate kinase
IMX20_RS05820	COG0072	phenylalanine-tRNA ligase activity
IMX20_RS05825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IMX20_RS05830	COG1733	regulation of RNA biosynthetic process
IMX20_RS05840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IMX20_RS05850	COG1187	pseudouridine synthase activity
IMX20_RS05855	COG2244	polysaccharide biosynthetic process
IMX20_RS05865	COG0495	leucyl-tRNA aminoacylation
IMX20_RS05870	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IMX20_RS05880	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
IMX20_RS05885	COG1388	LysM domain
IMX20_RS05885	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMX20_RS05890	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IMX20_RS05900	COG1278	Cold shock
IMX20_RS05910	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IMX20_RS05945	COG2759	Belongs to the formate--tetrahydrofolate ligase family
IMX20_RS05950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
IMX20_RS05960	COG0525	valine-tRNA ligase activity
IMX20_RS05965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMX20_RS05970	COG1940	carbohydrate kinase activity
IMX20_RS05975	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IMX20_RS05980	COG0705	Rhomboid family
IMX20_RS05980	COG0457	Tetratricopeptide repeat
IMX20_RS05985	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IMX20_RS05990	COG0768	penicillin binding
IMX20_RS06000	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IMX20_RS06010	COG0513	Belongs to the DEAD box helicase family
IMX20_RS06015	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
IMX20_RS06020	COG1744	ABC transporter substrate-binding protein PnrA-like
IMX20_RS06025	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
IMX20_RS06030	COG4109	DRTGG domain
IMX20_RS06050	COG1862	Preprotein translocase
IMX20_RS06055	COG0343	queuine tRNA-ribosyltransferase activity
IMX20_RS06070	COG4864	UPF0365 protein
IMX20_RS06080	COG0542	response to heat
IMX20_RS06090	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
IMX20_RS06105	COG1733	regulation of RNA biosynthetic process
IMX20_RS06110	COG1937	Protein conserved in bacteria
IMX20_RS06115	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IMX20_RS06120	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_RS06135	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMX20_RS06140	COG1132	(ABC) transporter
IMX20_RS06155	COG0151	Belongs to the GarS family
IMX20_RS06160	COG0138	bifunctional purine biosynthesis protein purh
IMX20_RS06165	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IMX20_RS06170	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IMX20_RS06175	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
IMX20_RS06180	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IMX20_RS06185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IMX20_RS06205	COG0673	inositol 2-dehydrogenase activity
IMX20_RS06210	COG1012	belongs to the aldehyde dehydrogenase family
IMX20_RS06215	COG0038	chloride channel
IMX20_RS06220	COG0335	large ribosomal subunit rRNA binding
IMX20_RS06240	COG0336	Belongs to the RNA methyltransferase TrmD family
IMX20_RS06255	COG0514	ATP-dependent DNA helicase (RecQ)
IMX20_RS06270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMX20_RS06280	COG1837	Belongs to the UPF0109 family
IMX20_RS06290	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IMX20_RS06295	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
IMX20_RS06300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMX20_RS06310	COG1940	carbohydrate kinase activity
IMX20_RS06315	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IMX20_RS06320	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IMX20_RS06325	COG4894	glucomannan catabolic process
IMX20_RS06330	COG0552	protein localization to endoplasmic reticulum
IMX20_RS06335	COG0561	phosphatase activity
IMX20_RS06340	COG1196	nuclear chromosome segregation
IMX20_RS06345	COG0571	ribonuclease III activity
IMX20_RS06350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IMX20_RS06355	COG0416	fatty acid biosynthetic process
IMX20_RS06360	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IMX20_RS06365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_RS06390	COG0708	Exodeoxyribonuclease III
IMX20_RS06400	COG1454	alcohol dehydrogenase
IMX20_RS06400	COG1012	belongs to the aldehyde dehydrogenase family
IMX20_RS06405	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
IMX20_RS06410	COG1882	Formate acetyltransferase
IMX20_RS06420	COG2151	metal-sulfur cluster biosynthetic enzyme
IMX20_RS06460	COG1879	ABC-type sugar transport system periplasmic component
IMX20_RS06475	COG1869	D-ribose catabolic process
IMX20_RS06480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_RS06490	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IMX20_RS06525	COG1091	dTDP-4-dehydrorhamnose reductase activity
IMX20_RS06535	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
IMX20_RS06540	COG1215	transferase activity, transferring glycosyl groups
IMX20_RS06560	COG0297	glycogen (starch) synthase activity
IMX20_RS06565	COG0110	maltose O-acetyltransferase activity
IMX20_RS06570	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMX20_RS06575	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMX20_RS06580	COG0489	protein tyrosine kinase activity
IMX20_RS06615	COG1216	Glycosyl transferase, family 2
IMX20_RS06630	COG0438	transferase activity, transferring glycosyl groups
IMX20_RS06635	COG0438	transferase activity, transferring glycosyl groups
IMX20_RS06640	COG0438	transferase activity, transferring glycosyl groups
IMX20_RS06650	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMX20_RS06655	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
IMX20_RS06660	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
IMX20_RS06665	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
IMX20_RS06670	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IMX20_RS06685	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IMX20_RS06700	COG1562	ergosterol biosynthetic process
IMX20_RS06730	COG1302	Protein conserved in bacteria
IMX20_RS06735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IMX20_RS06740	COG1564	THIamine pyrophosphokinase
IMX20_RS06745	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IMX20_RS06750	COG1162	GTPase activity
IMX20_RS06760	COG0631	protein serine/threonine phosphatase activity
IMX20_RS06765	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IMX20_RS06765	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IMX20_RS06770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IMX20_RS06775	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IMX20_RS06780	COG0402	S-adenosylhomocysteine deaminase activity
IMX20_RS06785	COG1758	RNA polymerase activity
IMX20_RS06790	COG0194	GDP metabolic process
IMX20_RS06800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
IMX20_RS06815	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IMX20_RS06820	COG1185	polyribonucleotide nucleotidyltransferase activity
IMX20_RS06825	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IMX20_RS06830	COG0671	phosphoesterase, PA-phosphatase related
IMX20_RS06835	COG0556	nucleotide-excision repair
IMX20_RS06845	COG1466	dna polymerase III delta subunit
IMX20_RS06855	COG1596	polysaccharide export
IMX20_RS06855	COG1555	photosystem II stabilization
IMX20_RS06860	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IMX20_RS06865	COG0742	ribosomal rna small subunit methyltransferase
IMX20_RS06885	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX20_RS06890	COG0783	Belongs to the Dps family
IMX20_RS06910	COG4471	UPF0298 protein
IMX20_RS06915	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
IMX20_RS06920	COG2190	(PTS) system
IMX20_RS06920	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS06920	COG1263	PTS System
IMX20_RS06930	COG0772	Belongs to the SEDS family
IMX20_RS06935	COG1217	gtp-binding protein TYPA
IMX20_RS06940	COG0483	inositol monophosphate 1-phosphatase activity
IMX20_RS06945	COG4476	Belongs to the UPF0223 family
IMX20_RS06970	COG0673	inositol 2-dehydrogenase activity
IMX20_RS06980	COG0534	Mate efflux family protein
IMX20_RS06985	COG3177	Filamentation induced by cAMP protein fic
IMX20_RS07000	COG0022	dehydrogenase e1 component
IMX20_RS07010	COG0242	peptide deformylase activity
IMX20_RS07015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IMX20_RS07045	COG3425	synthase
IMX20_RS07050	COG1904	glucuronate isomerase
IMX20_RS07060	COG0800	Aldolase
IMX20_RS07070	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_RS07075	COG1312	Catalyzes the dehydration of D-mannonate
IMX20_RS07085	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IMX20_RS07095	COG0765	amino acid transport
IMX20_RS07100	COG0765	amino acid transport
IMX20_RS07105	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IMX20_RS07150	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
IMX20_RS07170	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
IMX20_RS07185	COG1054	Belongs to the UPF0176 family
IMX20_RS07190	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IMX20_RS07195	COG4120	Belongs to the binding-protein-dependent transport system permease family
IMX20_RS07210	COG1876	peptidase activity
IMX20_RS07215	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
IMX20_RS07220	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
IMX20_RS07225	COG0252	asparaginase activity
IMX20_RS07235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_RS07245	COG0489	protein tyrosine kinase activity
IMX20_RS07260	COG4464	protein tyrosine phosphatase activity
IMX20_RS07265	COG1051	belongs to the nudix hydrolase family
IMX20_RS07275	COG1307	EDD domain protein, DegV family
IMX20_RS07305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
IMX20_RS07315	COG1316	TRANSCRIPTIONal
IMX20_RS07320	COG0024	Methionine aminopeptidase
IMX20_RS07330	COG0716	FMN binding
IMX20_RS07335	COG2309	aminopeptidase activity
IMX20_RS07345	COG2246	polysaccharide biosynthetic process
IMX20_RS07350	COG0463	Glycosyl transferase, family 2
IMX20_RS07370	COG1215	transferase activity, transferring glycosyl groups
IMX20_RS07395	COG0438	transferase activity, transferring glycosyl groups
IMX20_RS07410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IMX20_RS07415	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IMX20_RS07420	COG1121	(ABC) transporter
IMX20_RS07425	COG3443	Belongs to the bacterial solute-binding protein 9 family
IMX20_RS07425	COG0803	Belongs to the bacterial solute-binding protein 9 family
IMX20_RS07430	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
IMX20_RS07435	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IMX20_RS07445	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
IMX20_RS07450	COG4466	Protein conserved in bacteria
IMX20_RS07455	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IMX20_RS07465	COG0084	hydrolase, TatD family'
IMX20_RS07470	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX20_RS07470	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IMX20_RS07480	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IMX20_RS07490	COG2249	NAD(P)H dehydrogenase (quinone) activity
IMX20_RS07495	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IMX20_RS07520	COG2738	Putative neutral zinc metallopeptidase
IMX20_RS07540	COG1335	isochorismatase
IMX20_RS07545	COG0436	Aminotransferase
IMX20_RS07550	COG1522	sequence-specific DNA binding
IMX20_RS07565	COG1966	Carbon starvation protein
IMX20_RS07575	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_RS07605	COG4509	Sortase family
IMX20_RS07635	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IMX20_RS07640	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
IMX20_RS07645	COG0569	domain protein
IMX20_RS07650	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IMX20_RS07655	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
IMX20_RS07665	COG4853	Protein conserved in bacteria
IMX20_RS07675	COG5002	protein histidine kinase activity
IMX20_RS07680	COG0745	RESPONSE REGULATOR receiver
IMX20_RS07700	COG1472	Belongs to the glycosyl hydrolase 3 family
IMX20_RS07705	COG1073	alpha beta
IMX20_RS07710	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_RS07715	COG0628	permease
IMX20_RS07740	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
IMX20_RS07750	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_RS07755	COG0475	glutathione-regulated potassium exporter activity
IMX20_RS07760	COG0588	phosphoglycerate mutase activity
IMX20_RS07785	COG3527	Alpha-acetolactate decarboxylase
IMX20_RS07795	COG2826	transposase and inactivated derivatives, IS30 family
IMX20_RS07805	COG3588	fructose-bisphosphate aldolase
IMX20_RS07810	COG0531	amino acid
IMX20_RS07815	COG1621	beta-fructofuranosidase activity
IMX20_RS07840	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMX20_RS07845	COG4807	Protein conserved in bacteria
IMX20_RS07860	COG0753	catalase activity
IMX20_RS07865	COG1902	pentaerythritol trinitrate reductase activity
IMX20_RS07880	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_RS07885	COG0110	maltose O-acetyltransferase activity
IMX20_RS07890	COG0583	DNA-binding transcription factor activity
IMX20_RS07895	COG0564	pseudouridine synthase activity
IMX20_RS07910	COG2723	6-phospho-beta-galactosidase activity
IMX20_RS07915	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_RS07920	COG2188	Transcriptional regulator
IMX20_RS07925	COG4720	Psort location CytoplasmicMembrane, score
IMX20_RS07930	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
IMX20_RS07935	COG1447	Phosphotransferase system cellobiose-specific component IIA
IMX20_RS07955	COG0159	tryptophan synthase activity
IMX20_RS07960	COG0133	tryptophan synthase activity
IMX20_RS07970	COG0134	indole-3-glycerol-phosphate synthase activity
IMX20_RS07975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMX20_RS07980	COG0512	Glutamine amidotransferase of anthranilate synthase
IMX20_RS07980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IMX20_RS07990	COG4895	conserved protein (DUF2196)
IMX20_RS07995	COG2873	o-acetylhomoserine
IMX20_RS08000	COG1959	2 iron, 2 sulfur cluster binding
IMX20_RS08015	COG2321	neutral zinc metallopeptidase
IMX20_RS08030	COG0778	Nitroreductase
IMX20_RS08040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IMX20_RS08055	COG0446	pyridine nucleotide-disulphide oxidoreductase
IMX20_RS08115	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IMX20_RS08140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
IMX20_RS08145	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IMX20_RS08150	COG0154	amidase activity
IMX20_RS08160	COG4851	CamS sex pheromone cAM373 precursor
IMX20_RS08165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IMX20_RS08170	COG0210	DNA helicase
IMX20_RS08180	COG1705	Flagellar rod assembly protein muramidase FlgJ
IMX20_RS08225	COG0737	Belongs to the 5'-nucleotidase family
IMX20_RS08245	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
IMX20_RS08255	COG5002	protein histidine kinase activity
IMX20_RS08255	COG3850	Histidine kinase
IMX20_RS08260	COG0745	RESPONSE REGULATOR receiver
IMX20_RS08265	COG0629	single-stranded DNA binding
IMX20_RS08275	COG1481	regulation of sporulation
IMX20_RS08280	COG0391	Required for morphogenesis under gluconeogenic growth conditions
IMX20_RS08285	COG1660	Displays ATPase and GTPase activities
IMX20_RS08290	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMX20_RS08295	COG0492	ferredoxin-NADP+ reductase activity
IMX20_RS08300	COG1210	Utp--glucose-1-phosphate uridylyltransferase
IMX20_RS08305	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
IMX20_RS08325	COG1983	PspC domain protein
IMX20_RS08340	COG0419	ATPase involved in DNA repair
IMX20_RS08345	COG0420	3'-5' exonuclease activity
IMX20_RS08350	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IMX20_RS08355	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IMX20_RS08360	COG0581	inorganic phosphate transmembrane transporter activity
IMX20_RS08365	COG0573	inorganic phosphate transmembrane transporter activity
IMX20_RS08370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IMX20_RS08375	COG5002	protein histidine kinase activity
IMX20_RS08380	COG0745	RESPONSE REGULATOR receiver
IMX20_RS08390	COG0653	protein targeting
IMX20_RS08405	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
IMX20_RS08410	COG1307	EDD domain protein, DegV family
IMX20_RS08415	COG1739	Uncharacterized protein family UPF0029
IMX20_RS08420	COG0277	FAD linked oxidase domain protein
IMX20_RS08440	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
IMX20_RS08445	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
IMX20_RS08455	COG0765	amino acid transport
IMX20_RS08460	COG0431	NADPH-dependent FMN reductase
IMX20_RS08470	COG0765	amino acid transport
IMX20_RS08475	COG0165	Argininosuccinate lyase
IMX20_RS08485	COG0459	protein refolding
IMX20_RS08490	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IMX20_RS08500	COG0488	(ABC) transporter
IMX20_RS08515	COG0183	Belongs to the thiolase family
IMX20_RS08520	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
IMX20_RS08540	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
IMX20_RS08550	COG0494	nUDIX hydrolase
IMX20_RS08570	COG1394	ATPase activity, coupled to movement of substances
IMX20_RS08575	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
IMX20_RS08580	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
IMX20_RS08585	COG1436	Produces ATP from ADP in the presence of a proton gradient across the membrane
IMX20_RS08590	COG1527	subunit (C
IMX20_RS08600	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IMX20_RS08605	COG1269	ATP hydrolysis coupled proton transport
IMX20_RS08615	COG0590	tRNA wobble adenosine to inosine editing
IMX20_RS08620	COG1263	PTS System
IMX20_RS08620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS08625	COG0366	Alpha amylase catalytic
IMX20_RS08630	COG2188	Transcriptional regulator
IMX20_RS08650	COG0542	response to heat
IMX20_RS08660	COG0473	3-isopropylmalate dehydrogenase activity
IMX20_RS08665	COG2851	Citrate transporter
IMX20_RS08705	COG1131	(ABC) transporter
IMX20_RS08720	COG1940	carbohydrate kinase activity
IMX20_RS08730	COG0058	SHG alpha-glucan phosphorylase activity
IMX20_RS08735	COG1640	4-alpha-glucanotransferase
IMX20_RS08740	COG1609	Transcriptional regulator
IMX20_RS08755	COG0673	inositol 2-dehydrogenase activity
IMX20_RS08770	COG0673	inositol 2-dehydrogenase activity
IMX20_RS08775	COG3842	ATPase activity
IMX20_RS08785	COG3833	ABC-type maltose transport systems, permease component
IMX20_RS08790	COG1175	transmembrane transport
IMX20_RS08795	COG2182	Extracellular solute-binding protein
IMX20_RS08805	COG1263	PTS System
IMX20_RS08805	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS08805	COG2190	(PTS) system
IMX20_RS08820	COG1737	Transcriptional regulator
IMX20_RS08825	COG1486	melibiose metabolic process
IMX20_RS08830	COG1263	PTS System
IMX20_RS08830	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS08835	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IMX20_RS08865	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IMX20_RS08870	COG0456	acetyltransferase
IMX20_RS08875	COG0456	acetyltransferase
IMX20_RS08880	COG1214	PFAM Peptidase M22, glycoprotease
IMX20_RS08885	COG2211	Major facilitator Superfamily
IMX20_RS08890	COG0346	lactoylglutathione lyase activity
IMX20_RS08895	COG0400	carboxylic ester hydrolase activity
IMX20_RS08900	COG4224	UPF0291 protein
IMX20_RS08910	COG1263	PTS System
IMX20_RS08910	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
IMX20_RS08910	COG2190	(PTS) system
IMX20_RS08920	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IMX20_RS08930	COG0440	acetolactate synthase activity
IMX20_RS08935	COG0028	Belongs to the TPP enzyme family
IMX20_RS08940	COG1119	ATPase activity
IMX20_RS08950	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IMX20_RS08970	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
IMX20_RS08980	COG0561	phosphatase activity
IMX20_RS08985	COG0366	Alpha amylase catalytic
IMX20_RS08990	COG2252	PERMEase
IMX20_RS08995	COG1304	FMN binding
IMX20_RS09005	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
IMX20_RS09015	COG2226	methyltransferase
IMX20_RS09030	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_RS09040	COG1464	Belongs to the NlpA lipoprotein family
IMX20_RS09045	COG0436	Aminotransferase
IMX20_RS09060	COG0363	glucosamine-6-phosphate deaminase activity
IMX20_RS09065	COG1028	Short-chain dehydrogenase reductase Sdr
IMX20_RS09070	COG2323	membrane
IMX20_RS09075	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
IMX20_RS09080	COG1388	LysM domain
IMX20_RS09095	COG1187	pseudouridine synthase activity
IMX20_RS09105	COG4856	YbbR-like protein
IMX20_RS09110	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IMX20_RS09115	COG0789	Transcriptional regulator
IMX20_RS09120	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
IMX20_RS09130	COG1302	Protein conserved in bacteria
IMX20_RS09150	COG1486	melibiose metabolic process
IMX20_RS09170	COG0626	cystathionine gamma-synthase activity
IMX20_RS09175	COG2514	catechol 2,3-dioxygenase activity
IMX20_RS09185	COG0039	L-malate dehydrogenase activity
IMX20_RS09190	COG0589	response to stress
IMX20_RS09200	COG1363	Peptidase, m42
IMX20_RS09300	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
IMX20_RS09305	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IMX20_RS09320	COG0745	RESPONSE REGULATOR receiver
IMX20_RS09325	COG0517	IMP dehydrogenase activity
IMX20_RS09325	COG0516	GMP reductase activity
IMX20_RS09345	COG0012	GTP binding
IMX20_RS09350	COG4481	Protein conserved in bacteria
IMX20_RS09355	COG1475	DNA binding
IMX20_RS09360	COG1192	Involved in chromosome partitioning
IMX20_RS09365	COG0357	Ribosomal RNA small subunit methyltransferase G
IMX20_RS09375	COG0445	tRNA wobble uridine modification
IMX20_RS09380	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
IMX20_RS09390	COG0668	transmembrane transport
IMX20_RS09395	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
IMX20_RS09400	COG3711	transcriptional antiterminator
IMX20_RS09405	COG2213	PTS system mannitol-specific
IMX20_RS09410	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
IMX20_RS09415	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
IMX20_RS09420	COG1847	R3H domain protein
IMX20_RS09425	COG0706	membrane insertase activity
IMX20_RS09465	COG1192	Involved in chromosome partitioning
IMX20_RS09475	COG2124	cytochrome p450
IMX20_RS09500	COG0454	-acetyltransferase
IMX20_RS09530	COG0783	Belongs to the Dps family
IMX20_RS09535	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IMX20_RS09540	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IMX20_RS09545	COG2217	Heavy metal translocating P-type atpase
IMX20_RS09560	COG2217	Heavy metal translocating P-type atpase
IMX20_RS09620	COG0390	transport system, permease component
IMX20_RS09625	COG4619	ABC transporter
IMX20_RS09640	COG1388	LysM domain
IMX20_RS09650	COG3682	Transcriptional regulator
IMX20_RS09655	COG2217	Heavy metal translocating P-type atpase
IMX20_RS09670	COG2217	Heavy metal translocating P-type atpase
IMX20_RS09690	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
IMX20_RS09735	COG2814	Major facilitator Superfamily