locus-tag	class	description
Aeryth_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
Aeryth_RS00010	COG0592	DNA-directed DNA polymerase activity
Aeryth_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
Aeryth_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
Aeryth_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
Aeryth_RS00035	COG0187	DNA topoisomerase II activity
Aeryth_RS00040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Aeryth_RS00085	COG1131	(ABC) transporter
Aeryth_RS00090	COG0842	Transport permease protein
Aeryth_RS00095	COG4585	Histidine kinase
Aeryth_RS00100	COG2197	response regulator
Aeryth_RS00105	COG2372	response to copper ion
Aeryth_RS00105	COG1276	copper resistance
Aeryth_RS00150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Aeryth_RS00185	COG4172	Belongs to the ABC transporter superfamily
Aeryth_RS00190	COG0601	transmembrane transport
Aeryth_RS00195	COG4533	DNA binding
Aeryth_RS00210	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
Aeryth_RS00225	COG1024	Enoyl-CoA hydratase
Aeryth_RS00235	COG0705	Rhomboid family
Aeryth_RS00240	COG0300	oxidoreductase activity
Aeryth_RS00260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Aeryth_RS00285	COG0657	acetylesterase activity
Aeryth_RS00345	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS00350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Aeryth_RS00385	COG0179	Fumarylacetoacetate (FAA) hydrolase
Aeryth_RS00415	COG0477	Major facilitator Superfamily
Aeryth_RS00425	COG5002	protein histidine kinase activity
Aeryth_RS00435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Aeryth_RS00440	COG3654	unkown
Aeryth_RS00470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Aeryth_RS00480	COG0745	RESPONSE REGULATOR receiver
Aeryth_RS00490	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Aeryth_RS00495	COG1950	PFAM Membrane protein of
Aeryth_RS00505	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
Aeryth_RS00520	COG0022	dehydrogenase e1 component
Aeryth_RS00525	COG0508	dehydrogenase complex catalyzes the overall conversion of
Aeryth_RS00535	COG3619	membrane
Aeryth_RS00545	COG0154	amidase activity
Aeryth_RS00555	COG2351	hydroxyisourate hydrolase activity
Aeryth_RS00565	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Aeryth_RS00570	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
Aeryth_RS00590	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Aeryth_RS00590	COG2080	2 iron, 2 sulfur cluster binding
Aeryth_RS00600	COG0590	tRNA wobble adenosine to inosine editing
Aeryth_RS00665	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS00710	COG0004	ammonium transporteR
Aeryth_RS00725	COG0789	Transcriptional regulator
Aeryth_RS00730	COG0659	secondary active sulfate transmembrane transporter activity
Aeryth_RS00735	COG0640	Transcriptional regulator
Aeryth_RS00740	COG0798	PFAM Bile acid sodium symporter
Aeryth_RS00745	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
Aeryth_RS00750	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
Aeryth_RS00755	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Aeryth_RS00795	COG0717	Belongs to the dCTP deaminase family
Aeryth_RS00800	COG2313	pseudouridylate synthase activity
Aeryth_RS00805	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Aeryth_RS00820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Aeryth_RS00825	COG0247	lactate metabolic process
Aeryth_RS00825	COG2181	nitrate reductase activity
Aeryth_RS00830	COG2271	Major facilitator Superfamily
Aeryth_RS00870	COG1122	ATPase activity
Aeryth_RS00920	COG0154	amidase activity
Aeryth_RS00930	COG1054	Belongs to the UPF0176 family
Aeryth_RS00955	COG0667	Aldo Keto reductase
Aeryth_RS00960	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
Aeryth_RS00975	COG0577	efflux transmembrane transporter activity
Aeryth_RS00975	COG1136	(ABC) transporter
Aeryth_RS00985	COG2197	response regulator
Aeryth_RS00990	COG4585	Histidine kinase
Aeryth_RS01000	COG0443	Heat shock 70 kDa protein
Aeryth_RS01005	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Aeryth_RS01010	COG0484	heat shock protein binding
Aeryth_RS01015	COG0789	Transcriptional regulator
Aeryth_RS01095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Aeryth_RS01120	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
Aeryth_RS01160	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Aeryth_RS01220	COG1017	nitric oxide dioxygenase activity
Aeryth_RS01220	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
Aeryth_RS01225	COG0542	response to heat
Aeryth_RS01240	COG0446	pyridine nucleotide-disulphide oxidoreductase
Aeryth_RS01265	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Aeryth_RS01265	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Aeryth_RS01265	COG1703	isobutyryl-CoA mutase activity
Aeryth_RS01285	COG2610	gluconate transmembrane transporter activity
Aeryth_RS01305	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Aeryth_RS01325	COG3845	ABC transporter
Aeryth_RS01340	COG2045	Belongs to the ComB family
Aeryth_RS01410	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS01440	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS01460	COG2890	protein-(glutamine-N5) methyltransferase activity
Aeryth_RS01515	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS01520	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
Aeryth_RS01530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
Aeryth_RS01535	COG0583	DNA-binding transcription factor activity
Aeryth_RS01570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Aeryth_RS01585	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Aeryth_RS01600	COG1181	Belongs to the D-alanine--D-alanine ligase family
Aeryth_RS01645	COG1408	metallophosphoesterase
Aeryth_RS01655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Aeryth_RS01700	COG1217	gtp-binding protein TYPA
Aeryth_RS01710	COG0477	Major facilitator Superfamily
Aeryth_RS01720	COG0438	transferase activity, transferring glycosyl groups
Aeryth_RS01730	COG1116	anion transmembrane transporter activity
Aeryth_RS01740	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Aeryth_RS01750	COG0588	phosphoglycerate mutase activity
Aeryth_RS01780	COG1329	Transcriptional regulator
Aeryth_RS01785	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Aeryth_RS01795	COG0215	cysteine-tRNA ligase activity
Aeryth_RS01805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
Aeryth_RS01810	COG3619	membrane
Aeryth_RS01820	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Aeryth_RS01885	COG2318	DinB family
Aeryth_RS01895	COG1937	Protein conserved in bacteria
Aeryth_RS01920	COG0156	8-amino-7-oxononanoate synthase activity
Aeryth_RS01925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Aeryth_RS01930	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
Aeryth_RS01940	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Aeryth_RS01970	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
Aeryth_RS01975	COG2218	PFAM glutamate synthase alpha subunit domain protein
Aeryth_RS01980	COG0069	glutamate synthase activity
Aeryth_RS01995	COG1396	sequence-specific DNA binding
Aeryth_RS02000	COG0183	Belongs to the thiolase family
Aeryth_RS02005	COG0318	PFAM AMP-dependent synthetase and ligase
Aeryth_RS02010	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS02025	COG1129	ABC transporter
Aeryth_RS02030	COG1172	Belongs to the binding-protein-dependent transport system permease family
Aeryth_RS02035	COG1024	Enoyl-CoA hydratase
Aeryth_RS02065	COG2130	NADP-dependent
Aeryth_RS02085	COG3706	GGDEF domain
Aeryth_RS02095	COG1253	flavin adenine dinucleotide binding
Aeryth_RS02135	COG0438	transferase activity, transferring glycosyl groups
Aeryth_RS02180	COG0254	rRNA binding
Aeryth_RS02185	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Aeryth_RS02190	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Aeryth_RS02195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Aeryth_RS02200	COG0463	Glycosyl transferase, family 2
Aeryth_RS02225	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
Aeryth_RS02240	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
Aeryth_RS02280	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
Aeryth_RS02290	COG1278	Cold shock
Aeryth_RS02320	COG0459	protein refolding
Aeryth_RS02330	COG0110	maltose O-acetyltransferase activity
Aeryth_RS02340	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
Aeryth_RS02345	COG2011	ABC-type metal ion transport system permease component
Aeryth_RS02350	COG3483	tryptophan 2,3-dioxygenase activity
Aeryth_RS02355	COG1984	allophanate hydrolase subunit 2
Aeryth_RS02360	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
Aeryth_RS02365	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
Aeryth_RS02375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Aeryth_RS02380	COG0459	protein refolding
Aeryth_RS02450	COG0516	GMP reductase activity
Aeryth_RS02465	COG2837	iron assimilation
Aeryth_RS02470	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS02485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
Aeryth_RS02495	COG0519	Catalyzes the synthesis of GMP from XMP
Aeryth_RS02495	COG0518	GMP synthase (glutamine-hydrolyzing) activity
Aeryth_RS02500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
Aeryth_RS02505	COG0405	Gamma-glutamyltransferase
Aeryth_RS02535	COG4067	protein conserved in archaea
Aeryth_RS02535	COG0189	ligase activity
Aeryth_RS02540	COG0189	ligase activity
Aeryth_RS02540	COG0569	domain protein
Aeryth_RS02550	COG1902	pentaerythritol trinitrate reductase activity
Aeryth_RS02570	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Aeryth_RS02600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
Aeryth_RS02605	COG2409	Drug exporters of the RND superfamily
Aeryth_RS02610	COG1846	Transcriptional regulator
Aeryth_RS02615	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Aeryth_RS02660	COG1309	transcriptional regulator
Aeryth_RS02680	COG0778	Nitroreductase
Aeryth_RS02700	COG1125	glycine betaine transport
Aeryth_RS02700	COG0517	IMP dehydrogenase activity
Aeryth_RS02705	COG1174	glycine betaine transport
Aeryth_RS02710	COG1174	glycine betaine transport
Aeryth_RS02720	COG2267	carboxylic ester hydrolase activity
Aeryth_RS02725	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Aeryth_RS02755	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
Aeryth_RS02780	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Aeryth_RS02790	COG1320	monovalent cation:proton antiporter activity
Aeryth_RS02805	COG0651	ATP synthesis coupled electron transport
Aeryth_RS02810	COG1006	Multisubunit Na H antiporter MnhC subunit
Aeryth_RS02815	COG2111	Na H antiporter
Aeryth_RS02815	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Aeryth_RS02825	COG0037	tRNA processing
Aeryth_RS02840	COG0302	gtp cyclohydrolase
Aeryth_RS02845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
Aeryth_RS02855	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
Aeryth_RS02860	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Aeryth_RS02885	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Aeryth_RS02890	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
Aeryth_RS02895	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
Aeryth_RS02910	COG3237	CsbD-like
Aeryth_RS02925	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
Aeryth_RS02940	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
Aeryth_RS02945	COG1349	DNA-binding transcription factor activity
Aeryth_RS03020	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
Aeryth_RS03025	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
Aeryth_RS03040	COG0248	Ppx GppA phosphatase
Aeryth_RS03045	COG1082	Xylose isomerase domain protein TIM barrel
Aeryth_RS03050	COG1280	lysine exporter protein (LysE YggA)
Aeryth_RS03060	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
Aeryth_RS03065	COG0123	including yeast histone deacetylase and acetoin utilization protein
Aeryth_RS03090	COG1595	DNA-templated transcription, initiation
Aeryth_RS03100	COG0318	PFAM AMP-dependent synthetase and ligase
Aeryth_RS03110	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
Aeryth_RS03115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
Aeryth_RS03120	COG0181	hydroxymethylbilane synthase activity
Aeryth_RS03125	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Aeryth_RS03125	COG1648	precorrin-2 dehydrogenase activity
Aeryth_RS03130	COG0113	porphobilinogen synthase activity
Aeryth_RS03135	COG2826	transposase and inactivated derivatives, IS30 family
Aeryth_RS03145	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
Aeryth_RS03150	COG0406	alpha-ribazole phosphatase activity
Aeryth_RS03160	COG0785	Cytochrome C biogenesis protein
Aeryth_RS03170	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
Aeryth_RS03190	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
Aeryth_RS03215	COG0702	epimerase
Aeryth_RS03220	COG4948	Mandelate Racemase Muconate Lactonizing
Aeryth_RS03225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
Aeryth_RS03245	COG2226	methyltransferase
Aeryth_RS03255	COG0640	Transcriptional regulator
Aeryth_RS03265	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Aeryth_RS03270	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Aeryth_RS03275	COG0649	NAD binding
Aeryth_RS03290	COG1034	ATP synthesis coupled electron transport
Aeryth_RS03295	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
Aeryth_RS03300	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
Aeryth_RS03310	COG0713	ATP synthesis coupled electron transport
Aeryth_RS03315	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
Aeryth_RS03325	COG1007	ATP synthesis coupled electron transport
Aeryth_RS03330	COG0142	geranyltranstransferase activity
Aeryth_RS03360	COG1666	GTP binding
Aeryth_RS03420	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
Aeryth_RS03445	COG3842	ATPase activity
Aeryth_RS03450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
Aeryth_RS03455	COG1176	ABC-type spermidine putrescine transport system, permease component I
Aeryth_RS03460	COG1177	transmembrane transport
Aeryth_RS03465	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS03470	COG0167	dihydroorotate dehydrogenase activity
Aeryth_RS03485	COG0267	Belongs to the bacterial ribosomal protein bL33 family
Aeryth_RS03490	COG0812	UDP-N-acetylmuramate dehydrogenase activity
Aeryth_RS03500	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Aeryth_RS03520	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Aeryth_RS03530	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
Aeryth_RS03535	COG0081	regulation of translation
Aeryth_RS03540	COG5002	protein histidine kinase activity
Aeryth_RS03575	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
Aeryth_RS03580	COG0222	ribosome binding
Aeryth_RS03590	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Aeryth_RS03595	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
Aeryth_RS03640	COG0085	RNA polymerase activity
Aeryth_RS03645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
Aeryth_RS03650	COG3594	Acyltransferase
Aeryth_RS03655	COG0494	nUDIX hydrolase
Aeryth_RS03665	COG1802	Transcriptional regulator
Aeryth_RS03675	COG0277	FAD linked oxidase domain protein
Aeryth_RS03675	COG0247	lactate metabolic process
Aeryth_RS03690	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
Aeryth_RS03695	COG0151	Belongs to the GarS family
Aeryth_RS03705	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
Aeryth_RS03710	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
Aeryth_RS03715	COG0318	PFAM AMP-dependent synthetase and ligase
Aeryth_RS03725	COG2084	Dehydrogenase
Aeryth_RS03730	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
Aeryth_RS03735	COG0047	phosphoribosylformylglycinamidine synthase activity
Aeryth_RS03750	COG0513	Belongs to the DEAD box helicase family
Aeryth_RS03765	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Aeryth_RS03780	COG4303	Ethanolamine ammonia lyase large subunit
Aeryth_RS03785	COG0531	amino acid
Aeryth_RS03810	COG2197	response regulator
Aeryth_RS03820	COG0025	NhaP-type Na H and K H
Aeryth_RS03825	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Aeryth_RS03835	COG1725	Transcriptional regulator
Aeryth_RS03850	COG0739	heme binding
Aeryth_RS03850	COG0741	lytic transglycosylase activity
Aeryth_RS03850	COG1196	nuclear chromosome segregation
Aeryth_RS03860	COG0045	succinate-CoA ligase (ADP-forming) activity
Aeryth_RS03885	COG0138	bifunctional purine biosynthesis protein purh
Aeryth_RS03905	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
Aeryth_RS03920	COG0039	L-malate dehydrogenase activity
Aeryth_RS03930	COG2838	Isocitrate dehydrogenase
Aeryth_RS03935	COG2814	Major facilitator Superfamily
Aeryth_RS03955	COG4208	sulfate ABC transporter
Aeryth_RS03965	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
Aeryth_RS03990	COG1605	Chorismate mutase
Aeryth_RS03990	COG0077	Prephenate dehydratase
Aeryth_RS03995	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
Aeryth_RS04000	COG0180	Tryptophanyl-tRNA synthetase
Aeryth_RS04020	COG0583	DNA-binding transcription factor activity
Aeryth_RS04030	COG1053	succinate dehydrogenase
Aeryth_RS04055	COG1473	amidohydrolase
Aeryth_RS04055	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Aeryth_RS04060	COG1744	ABC transporter substrate-binding protein PnrA-like
Aeryth_RS04065	COG3845	ABC transporter
Aeryth_RS04070	COG4603	Belongs to the binding-protein-dependent transport system permease family
Aeryth_RS04075	COG1079	Belongs to the binding-protein-dependent transport system permease family
Aeryth_RS04100	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS04105	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS04110	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
Aeryth_RS04115	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Aeryth_RS04130	COG0737	Belongs to the 5'-nucleotidase family
Aeryth_RS04155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
Aeryth_RS04160	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
Aeryth_RS04165	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
Aeryth_RS04185	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Aeryth_RS04220	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
Aeryth_RS04230	COG1278	Cold shock
Aeryth_RS04250	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Aeryth_RS04255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
Aeryth_RS04260	COG0667	Aldo Keto reductase
Aeryth_RS04280	COG1162	GTPase activity
Aeryth_RS04295	COG2353	YceI-like domain
Aeryth_RS04305	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS04310	COG0183	Belongs to the thiolase family
Aeryth_RS04315	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS04320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Aeryth_RS04320	COG3319	amino acid activation for nonribosomal peptide biosynthetic process
Aeryth_RS04320	COG3321	synthase
Aeryth_RS04325	COG0736	holo-[acyl-carrier-protein] synthase activity
Aeryth_RS04350	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Aeryth_RS04355	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
Aeryth_RS04370	COG0668	transmembrane transport
Aeryth_RS04385	COG2226	methyltransferase
Aeryth_RS04390	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
Aeryth_RS04405	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Aeryth_RS04405	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
Aeryth_RS04410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Aeryth_RS04420	COG0243	molybdopterin cofactor binding
Aeryth_RS04425	COG2223	nitrite transmembrane transporter activity
Aeryth_RS04430	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
Aeryth_RS04435	COG0657	acetylesterase activity
Aeryth_RS04450	COG2770	Histidine kinase
Aeryth_RS04450	COG2208	phosphoserine phosphatase activity
Aeryth_RS04480	COG1902	pentaerythritol trinitrate reductase activity
Aeryth_RS04520	COG1295	ribonuclease BN
Aeryth_RS04525	COG4565	transcriptional regulatory protein
Aeryth_RS04530	COG3290	protein histidine kinase activity
Aeryth_RS04550	COG0589	response to stress
Aeryth_RS04565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
Aeryth_RS04615	COG2124	cytochrome p450
Aeryth_RS04625	COG0723	plastoquinol--plastocyanin reductase activity
Aeryth_RS04675	COG3239	Fatty acid desaturase
Aeryth_RS04715	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Aeryth_RS04720	COG0084	hydrolase, TatD family'
Aeryth_RS04725	COG3583	domain protein
Aeryth_RS04730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
Aeryth_RS04735	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
Aeryth_RS04740	COG0488	(ABC) transporter
Aeryth_RS04755	COG4106	trans-aconitate 2-methyltransferase activity
Aeryth_RS04770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
Aeryth_RS04775	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Aeryth_RS04810	COG2205	protein histidine kinase activity
Aeryth_RS04815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
Aeryth_RS04820	COG0193	aminoacyl-tRNA hydrolase activity
Aeryth_RS04845	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
Aeryth_RS04850	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Aeryth_RS04865	COG2385	sporulation resulting in formation of a cellular spore
Aeryth_RS04875	COG4770	biotin carboxylase activity
Aeryth_RS04880	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS04890	COG0424	maF-like protein
Aeryth_RS04905	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Aeryth_RS04910	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
Aeryth_RS04910	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
Aeryth_RS04920	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Aeryth_RS04925	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
Aeryth_RS04935	COG0579	oxidoreductase
Aeryth_RS04965	COG1316	TRANSCRIPTIONal
Aeryth_RS04980	COG1388	LysM domain
Aeryth_RS04980	COG1134	teichoic acid transport
Aeryth_RS05025	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
Aeryth_RS05030	COG0745	RESPONSE REGULATOR receiver
Aeryth_RS05035	COG5002	protein histidine kinase activity
Aeryth_RS05040	COG5401	PFAM Sporulation and spore germination
Aeryth_RS05050	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
Aeryth_RS05055	COG2197	response regulator
Aeryth_RS05060	COG3214	Protein conserved in bacteria
Aeryth_RS05065	COG0653	protein targeting
Aeryth_RS05115	COG1842	Phage shock protein A
Aeryth_RS05125	COG0463	Glycosyl transferase, family 2
Aeryth_RS05130	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
Aeryth_RS05135	COG2205	protein histidine kinase activity
Aeryth_RS05140	COG0745	RESPONSE REGULATOR receiver
Aeryth_RS05150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Aeryth_RS05215	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
Aeryth_RS05220	COG3546	catalase activity
Aeryth_RS05235	COG0537	adenosine 5'-monophosphoramidase activity
Aeryth_RS05240	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
Aeryth_RS05255	COG1120	ATPase activity
Aeryth_RS05260	COG2318	DinB family
Aeryth_RS05270	COG2884	Cell division ATP-binding protein ftsE
Aeryth_RS05285	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
Aeryth_RS05295	COG0477	Major facilitator Superfamily
Aeryth_RS05300	COG2356	endonuclease I
Aeryth_RS05315	COG2801	Transposase and inactivated derivatives
Aeryth_RS05320	COG2963	transposase activity
Aeryth_RS05340	COG4221	oxidoreductase activity
Aeryth_RS05355	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Aeryth_RS05360	COG1121	(ABC) transporter
Aeryth_RS05370	COG0803	Belongs to the bacterial solute-binding protein 9 family
Aeryth_RS05395	COG2154	pterin-4-alpha-carbinolamine dehydratase
Aeryth_RS05405	COG2072	flavoprotein involved in K transport
Aeryth_RS05420	COG1201	RNA secondary structure unwinding
Aeryth_RS05425	COG1470	cell adhesion involved in biofilm formation
Aeryth_RS05430	COG1309	transcriptional regulator
Aeryth_RS05445	COG1678	Uncharacterized ACR, COG1678
Aeryth_RS05460	COG0657	acetylesterase activity
Aeryth_RS05470	COG0318	PFAM AMP-dependent synthetase and ligase
Aeryth_RS05480	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Aeryth_RS05485	COG1335	isochorismatase
Aeryth_RS05495	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
Aeryth_RS05510	COG0666	response to abiotic stimulus
Aeryth_RS05515	COG1802	Transcriptional regulator
Aeryth_RS05535	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
Aeryth_RS05540	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Aeryth_RS05545	COG0765	amino acid transport
Aeryth_RS05550	COG1126	abc transporter atp-binding protein
Aeryth_RS05555	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
Aeryth_RS05560	COG1234	tRNA 3'-trailer cleavage
Aeryth_RS05565	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
Aeryth_RS05570	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
Aeryth_RS05580	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
Aeryth_RS05610	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
Aeryth_RS05615	COG4129	membrane
Aeryth_RS05635	COG2301	Belongs to the HpcH HpaI aldolase family
Aeryth_RS05645	COG2171	N-acyltransferase activity
Aeryth_RS05655	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Aeryth_RS05665	COG4221	oxidoreductase activity
Aeryth_RS05670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Aeryth_RS05675	COG1611	Belongs to the LOG family
Aeryth_RS05685	COG0519	Catalyzes the synthesis of GMP from XMP
Aeryth_RS05705	COG4122	O-methyltransferase activity
Aeryth_RS05710	COG1595	DNA-templated transcription, initiation
Aeryth_RS05720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Aeryth_RS05735	COG2239	Acts as a magnesium transporter
Aeryth_RS05745	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
Aeryth_RS05755	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Aeryth_RS05755	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
Aeryth_RS05765	COG0657	acetylesterase activity
Aeryth_RS05785	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS05805	COG2030	dehydratase
Aeryth_RS05810	COG0406	alpha-ribazole phosphatase activity
Aeryth_RS05815	COG0613	PHP domain protein
Aeryth_RS05825	COG1309	transcriptional regulator
Aeryth_RS05835	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
Aeryth_RS05845	COG0300	oxidoreductase activity
Aeryth_RS05850	COG1192	Involved in chromosome partitioning
Aeryth_RS05855	COG0513	Belongs to the DEAD box helicase family
Aeryth_RS05875	COG1309	transcriptional regulator
Aeryth_RS05890	COG0210	DNA helicase
Aeryth_RS05925	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
Aeryth_RS05955	COG3480	Lon protease (S16) C-terminal proteolytic domain
Aeryth_RS05965	COG1615	UPF0182 protein
Aeryth_RS06000	COG2815	serine threonine protein kinase
Aeryth_RS06000	COG0515	serine threonine protein kinase
Aeryth_RS06005	COG0515	serine threonine protein kinase
Aeryth_RS06005	COG2815	serine threonine protein kinase
Aeryth_RS06025	COG2409	Drug exporters of the RND superfamily
Aeryth_RS06075	COG2197	response regulator
Aeryth_RS06085	COG2909	trisaccharide binding
Aeryth_RS06090	COG2801	Transposase and inactivated derivatives
Aeryth_RS06090	COG3415	Transposase
Aeryth_RS06100	COG0745	RESPONSE REGULATOR receiver
Aeryth_RS06105	COG2205	protein histidine kinase activity
Aeryth_RS06130	COG3158	transport of potassium into the cell
Aeryth_RS06190	COG0754	glutathionylspermidine amidase activity
Aeryth_RS06200	COG2205	protein histidine kinase activity
Aeryth_RS06215	COG1216	Glycosyl transferase, family 2
Aeryth_RS06225	COG0586	Pfam SNARE associated Golgi protein
Aeryth_RS06235	COG2409	Drug exporters of the RND superfamily
Aeryth_RS06245	COG2010	Cytochrome c
Aeryth_RS06245	COG1529	Aldehyde oxidase and xanthine dehydrogenase
Aeryth_RS06250	COG2080	2 iron, 2 sulfur cluster binding
Aeryth_RS06255	COG3608	succinylglutamate desuccinylase aspartoacylase
Aeryth_RS06255	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
Aeryth_RS06285	COG3781	membrane
Aeryth_RS06290	COG0657	acetylesterase activity
Aeryth_RS06335	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS06370	COG1690	Belongs to the RtcB family
Aeryth_RS06385	COG1309	transcriptional regulator
Aeryth_RS06405	COG3177	Filamentation induced by cAMP protein fic
Aeryth_RS06415	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Aeryth_RS06420	COG0483	inositol monophosphate 1-phosphatase activity
Aeryth_RS06435	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
Aeryth_RS06455	COG2135	peptidase activity
Aeryth_RS06460	COG1595	DNA-templated transcription, initiation
Aeryth_RS06480	COG1132	(ABC) transporter
Aeryth_RS06515	COG0604	alcohol dehydrogenase
Aeryth_RS06535	COG0508	dehydrogenase complex catalyzes the overall conversion of
Aeryth_RS06535	COG0567	Dehydrogenase, E1 component
Aeryth_RS06550	COG2066	Belongs to the glutaminase family
Aeryth_RS06555	COG1764	response to oxidative stress
Aeryth_RS06565	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Aeryth_RS06590	COG0018	arginyl-trna synthetase
Aeryth_RS06595	COG0019	diaminopimelate decarboxylase activity
Aeryth_RS06615	COG0789	Transcriptional regulator
Aeryth_RS06625	COG0460	homoserine dehydrogenase
Aeryth_RS06630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
Aeryth_RS06635	COG0083	homoserine kinase activity
Aeryth_RS06645	COG0386	Belongs to the glutathione peroxidase family
Aeryth_RS06650	COG0254	rRNA binding
Aeryth_RS06655	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
Aeryth_RS06660	COG2890	protein-(glutamine-N5) methyltransferase activity
Aeryth_RS06675	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Aeryth_RS06685	COG0356	it plays a direct role in the translocation of protons across the membrane
Aeryth_RS06690	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Aeryth_RS06695	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
Aeryth_RS06700	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
Aeryth_RS06705	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
Aeryth_RS06710	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
Aeryth_RS06715	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
Aeryth_RS06720	COG0355	proton-transporting ATP synthase activity, rotational mechanism
Aeryth_RS06735	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Aeryth_RS06735	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
Aeryth_RS06765	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
Aeryth_RS06775	COG1250	3-hydroxyacyl-CoA dehydrogenase
Aeryth_RS06810	COG0583	DNA-binding transcription factor activity
Aeryth_RS06815	COG0183	Belongs to the thiolase family
Aeryth_RS06820	COG1703	isobutyryl-CoA mutase activity
Aeryth_RS06845	COG0494	nUDIX hydrolase
Aeryth_RS06850	COG0366	Alpha amylase catalytic
Aeryth_RS06870	COG2086	electron transfer activity
Aeryth_RS06875	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
Aeryth_RS06880	COG0747	negative chemotaxis
Aeryth_RS06885	COG0601	transmembrane transport
Aeryth_RS06890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
Aeryth_RS06895	COG4172	Belongs to the ABC transporter superfamily
Aeryth_RS06905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Aeryth_RS06910	COG0587	DNA-directed DNA polymerase activity
Aeryth_RS06930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
Aeryth_RS06935	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
Aeryth_RS06945	COG1104	cysteine desulfurase activity
Aeryth_RS06955	COG0482	sulfurtransferase activity
Aeryth_RS06965	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
Aeryth_RS06970	COG2326	polyphosphate kinase activity
Aeryth_RS06975	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Aeryth_RS06980	COG0154	amidase activity
Aeryth_RS06985	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
Aeryth_RS06995	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Aeryth_RS07020	COG0129	dihydroxy-acid dehydratase activity
Aeryth_RS07035	COG0440	acetolactate synthase activity
Aeryth_RS07040	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
Aeryth_RS07050	COG0352	thiamine-phosphate diphosphorylase activity
Aeryth_RS07055	COG0351	phosphomethylpyrimidine kinase
Aeryth_RS07060	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
Aeryth_RS07060	COG0352	thiamine-phosphate diphosphorylase activity
Aeryth_RS07060	COG0351	phosphomethylpyrimidine kinase
Aeryth_RS07065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Aeryth_RS07070	COG2364	Membrane
Aeryth_RS07080	COG0473	3-isopropylmalate dehydrogenase activity
Aeryth_RS07085	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Aeryth_RS07095	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
Aeryth_RS07120	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Aeryth_RS07130	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Aeryth_RS07165	COG1027	Aspartate ammonia-lyase
Aeryth_RS07175	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Aeryth_RS07200	COG1108	ABC-type Mn2 Zn2 transport systems permease components
Aeryth_RS07205	COG1121	(ABC) transporter
Aeryth_RS07210	COG0803	Belongs to the bacterial solute-binding protein 9 family
Aeryth_RS07215	COG0423	glycine-tRNA ligase activity
Aeryth_RS07250	COG0824	Thioesterase
Aeryth_RS07270	COG1271	oxidase subunit
Aeryth_RS07275	COG1294	oxidase, subunit
Aeryth_RS07280	COG4988	ABC transporter
Aeryth_RS07285	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
Aeryth_RS07305	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
Aeryth_RS07330	COG1024	Enoyl-CoA hydratase
Aeryth_RS07335	COG0228	four-way junction DNA binding
Aeryth_RS07340	COG1837	Belongs to the UPF0109 family
Aeryth_RS07345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
Aeryth_RS07350	COG0336	Belongs to the RNA methyltransferase TrmD family
Aeryth_RS07360	COG0335	large ribosomal subunit rRNA binding
Aeryth_RS07365	COG0681	Belongs to the peptidase S26 family
Aeryth_RS07370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
Aeryth_RS07385	COG0792	nuclease activity
Aeryth_RS07400	COG4974	Belongs to the 'phage' integrase family
Aeryth_RS07445	COG0739	heme binding
Aeryth_RS07445	COG0741	lytic transglycosylase activity
Aeryth_RS07445	COG1196	nuclear chromosome segregation
Aeryth_RS07450	COG0052	Belongs to the universal ribosomal protein uS2 family
Aeryth_RS07455	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
Aeryth_RS07460	COG0528	UMP kinase activity
Aeryth_RS07465	COG0233	cytoplasmic translational termination
Aeryth_RS07470	COG0575	Belongs to the CDS family
Aeryth_RS07480	COG2307	Protein conserved in bacteria
Aeryth_RS07480	COG2308	Evidence 4 Homologs of previously reported genes of
Aeryth_RS07495	COG0820	rRNA (adenine-C2-)-methyltransferase activity
Aeryth_RS07500	COG0561	phosphatase activity
Aeryth_RS07525	COG2197	response regulator
Aeryth_RS07530	COG4585	Histidine kinase
Aeryth_RS07535	COG1131	(ABC) transporter
Aeryth_RS07550	COG0750	zinc metalloprotease
Aeryth_RS07555	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
Aeryth_RS07575	COG0442	prolyl-tRNA aminoacylation
Aeryth_RS07590	COG0779	Required for maturation of 30S ribosomal subunits
Aeryth_RS07605	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
Aeryth_RS07610	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
Aeryth_RS07615	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
Aeryth_RS07620	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
Aeryth_RS07630	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Aeryth_RS07630	COG0515	serine threonine protein kinase
Aeryth_RS07635	COG0745	RESPONSE REGULATOR receiver
Aeryth_RS07640	COG2205	protein histidine kinase activity
Aeryth_RS07655	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
Aeryth_RS07660	COG1185	polyribonucleotide nucleotidyltransferase activity
Aeryth_RS07670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
Aeryth_RS07705	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
Aeryth_RS07730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
Aeryth_RS07735	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
Aeryth_RS07745	COG1674	ftsk spoiiie
Aeryth_RS07760	COG1058	Belongs to the CinA family
Aeryth_RS07760	COG1546	Belongs to the CinA family
Aeryth_RS07785	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
Aeryth_RS07790	COG2137	regulation of response to DNA damage stimulus
Aeryth_RS07805	COG0765	amino acid transport
Aeryth_RS07810	COG0765	amino acid transport
Aeryth_RS07820	COG1126	abc transporter atp-binding protein
Aeryth_RS07845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
Aeryth_RS07850	COG1982	Orn Lys Arg decarboxylase major
Aeryth_RS07860	COG2409	Drug exporters of the RND superfamily
Aeryth_RS07865	COG1309	transcriptional regulator
Aeryth_RS07890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
Aeryth_RS07895	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
Aeryth_RS07900	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
Aeryth_RS07910	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
Aeryth_RS07930	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
Aeryth_RS07935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Aeryth_RS07990	COG1074	ATP-dependent DNA helicase activity
Aeryth_RS07995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Aeryth_RS08015	COG1764	response to oxidative stress
Aeryth_RS08025	COG2815	serine threonine protein kinase
Aeryth_RS08025	COG0515	serine threonine protein kinase
Aeryth_RS08045	COG0778	Nitroreductase
Aeryth_RS08050	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS08060	COG3265	gluconokinase activity
Aeryth_RS08070	COG2610	gluconate transmembrane transporter activity
Aeryth_RS08075	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Aeryth_RS08080	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Aeryth_RS08085	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Aeryth_RS08100	COG1278	Cold shock
Aeryth_RS08115	COG2814	Major facilitator Superfamily
Aeryth_RS08130	COG0708	Exodeoxyribonuclease III
Aeryth_RS08140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Aeryth_RS08155	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
Aeryth_RS08190	COG0187	DNA topoisomerase II activity
Aeryth_RS08205	COG0477	Major facilitator Superfamily
Aeryth_RS08215	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
Aeryth_RS08235	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
Aeryth_RS08240	COG1435	thymidine kinase activity
Aeryth_RS08250	COG2860	membrane
Aeryth_RS08255	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS08265	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
Aeryth_RS08290	COG0756	dUTP diphosphatase activity
Aeryth_RS08315	COG0569	domain protein
Aeryth_RS08320	COG0531	amino acid
Aeryth_RS08325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
Aeryth_RS08345	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
Aeryth_RS08355	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
Aeryth_RS08370	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
Aeryth_RS08375	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Aeryth_RS08375	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Aeryth_RS08385	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Aeryth_RS08385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
Aeryth_RS08390	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
Aeryth_RS08395	COG0140	phosphoribosyl-ATP diphosphatase activity
Aeryth_RS08400	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
Aeryth_RS08420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
Aeryth_RS08430	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
Aeryth_RS08435	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
Aeryth_RS08445	COG5002	protein histidine kinase activity
Aeryth_RS08450	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
Aeryth_RS08455	COG0072	phenylalanine-tRNA ligase activity
Aeryth_RS08455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
Aeryth_RS08460	COG0137	argininosuccinate synthase activity
Aeryth_RS08465	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
Aeryth_RS08470	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
Aeryth_RS08475	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
Aeryth_RS08485	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
Aeryth_RS08490	COG1438	arginine binding
Aeryth_RS08495	COG0165	Argininosuccinate lyase
Aeryth_RS08505	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
Aeryth_RS08520	COG1846	Transcriptional regulator
Aeryth_RS08525	COG0483	inositol monophosphate 1-phosphatase activity
Aeryth_RS08535	COG0494	nUDIX hydrolase
Aeryth_RS08560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
Aeryth_RS08580	COG3336	cytochrome c oxidase
Aeryth_RS08610	COG0509	glycine decarboxylation via glycine cleavage system
Aeryth_RS08615	COG1716	ATPase activity
Aeryth_RS08635	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Aeryth_RS08635	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Aeryth_RS08675	COG1595	DNA-templated transcription, initiation
Aeryth_RS08695	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Aeryth_RS08695	COG1648	precorrin-2 dehydrogenase activity
Aeryth_RS08720	COG0175	sulfate reduction
Aeryth_RS08735	COG0009	L-threonylcarbamoyladenylate synthase
Aeryth_RS08760	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
Aeryth_RS08765	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
Aeryth_RS08785	COG1522	sequence-specific DNA binding
Aeryth_RS08810	COG0697	spore germination
Aeryth_RS08815	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Aeryth_RS08825	COG0738	Major facilitator superfamily
Aeryth_RS08835	COG0596	Alpha beta hydrolase
Aeryth_RS08840	COG0657	acetylesterase activity
Aeryth_RS08845	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
Aeryth_RS08875	COG1216	Glycosyl transferase, family 2
Aeryth_RS08895	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
Aeryth_RS08910	COG0805	protein transport
Aeryth_RS08935	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Aeryth_RS08940	COG0667	Aldo Keto reductase
Aeryth_RS08950	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Aeryth_RS08955	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
Aeryth_RS08965	COG4122	O-methyltransferase activity
Aeryth_RS08980	COG1222	aaa ATPase
Aeryth_RS08990	COG0517	IMP dehydrogenase activity
Aeryth_RS08990	COG1994	Peptidase M50
Aeryth_RS08995	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
Aeryth_RS09020	COG0215	cysteine-tRNA ligase activity
Aeryth_RS09035	COG0598	Magnesium transport protein CorA
Aeryth_RS09065	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
Aeryth_RS09070	COG0598	Magnesium transport protein CorA
Aeryth_RS09080	COG1968	undecaprenyl-diphosphatase activity
Aeryth_RS09085	COG0667	Aldo Keto reductase
Aeryth_RS09095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
Aeryth_RS09105	COG0542	response to heat
Aeryth_RS09125	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
Aeryth_RS09135	COG2733	membrane
Aeryth_RS09150	COG1643	Atp-dependent helicase
Aeryth_RS09155	COG0545	Peptidyl-prolyl cis-trans isomerase
Aeryth_RS09170	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS09180	COG0242	peptide deformylase activity
Aeryth_RS09195	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Aeryth_RS09230	COG1881	PFAM PEBP family protein
Aeryth_RS09245	COG1119	ATPase activity
Aeryth_RS09250	COG0560	Phosphoserine phosphatase
Aeryth_RS09250	COG3830	Belongs to the UPF0237 family
Aeryth_RS09255	COG3360	Dodecin
Aeryth_RS09270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
Aeryth_RS09285	COG0488	(ABC) transporter
Aeryth_RS09290	COG2151	metal-sulfur cluster biosynthetic enzyme
Aeryth_RS09295	COG0822	iron-sulfur transferase activity
Aeryth_RS09300	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
Aeryth_RS09305	COG0396	ATPase activity
Aeryth_RS09340	COG2357	RelA SpoT domain protein
Aeryth_RS09345	COG1793	dna ligase
Aeryth_RS09350	COG1131	(ABC) transporter
Aeryth_RS09360	COG1612	heme a metabolic process
Aeryth_RS09370	COG0109	protoheme IX farnesyltransferase activity
Aeryth_RS09380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
Aeryth_RS09385	COG0166	Belongs to the GPI family
Aeryth_RS09400	COG0363	glucosamine-6-phosphate deaminase activity
Aeryth_RS09410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
Aeryth_RS09415	COG0149	triose-phosphate isomerase activity
Aeryth_RS09420	COG0126	phosphoglycerate kinase activity
Aeryth_RS09425	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
Aeryth_RS09430	COG2890	protein-(glutamine-N5) methyltransferase activity
Aeryth_RS09435	COG1481	regulation of sporulation
Aeryth_RS09440	COG0391	Required for morphogenesis under gluconeogenic growth conditions
Aeryth_RS09445	COG1660	Displays ATPase and GTPase activities
Aeryth_RS09450	COG0322	excinuclease ABC activity
Aeryth_RS09460	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
Aeryth_RS09480	COG2124	cytochrome p450
Aeryth_RS09485	COG0531	amino acid
Aeryth_RS09510	COG0556	nucleotide-excision repair
Aeryth_RS09520	COG0183	Belongs to the thiolase family
Aeryth_RS09525	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS09530	COG2030	dehydratase
Aeryth_RS09540	COG1946	Acyl-CoA thioesterase
Aeryth_RS09550	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Aeryth_RS09560	COG3540	Alkaline phosphatase
Aeryth_RS09565	COG1070	Carbohydrate kinase
Aeryth_RS09585	COG4214	carbohydrate transport
Aeryth_RS09595	COG4213	ABC transporter substrate-binding protein
Aeryth_RS09600	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
Aeryth_RS09610	COG1758	RNA polymerase activity
Aeryth_RS09615	COG0194	GDP metabolic process
Aeryth_RS09630	COG0284	orotidine-5'-phosphate decarboxylase activity
Aeryth_RS09635	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
Aeryth_RS09640	COG0505	Belongs to the CarA family
Aeryth_RS09645	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
Aeryth_RS09650	COG0540	Belongs to the ATCase OTCase family
Aeryth_RS09655	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
Aeryth_RS09680	COG1174	glycine betaine transport
Aeryth_RS09685	COG1125	glycine betaine transport
Aeryth_RS09685	COG0517	IMP dehydrogenase activity
Aeryth_RS09690	COG1174	glycine betaine transport
Aeryth_RS09695	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
Aeryth_RS09700	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
Aeryth_RS09710	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
Aeryth_RS09715	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
Aeryth_RS09720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
Aeryth_RS09740	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
Aeryth_RS09745	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
Aeryth_RS09750	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
Aeryth_RS09780	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
Aeryth_RS09785	COG0124	histidyl-tRNA synthetase
Aeryth_RS09795	COG1196	nuclear chromosome segregation
Aeryth_RS09815	COG1215	transferase activity, transferring glycosyl groups
Aeryth_RS09820	COG1366	Belongs to the anti-sigma-factor antagonist family
Aeryth_RS09835	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
Aeryth_RS09840	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
Aeryth_RS09850	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Aeryth_RS09855	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Aeryth_RS09865	COG2255	four-way junction helicase activity
Aeryth_RS09870	COG0632	four-way junction helicase activity
Aeryth_RS09875	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
Aeryth_RS09880	COG0217	transcriptional regulatory protein
Aeryth_RS09885	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
Aeryth_RS09890	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
Aeryth_RS09905	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
Aeryth_RS09920	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
Aeryth_RS09935	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
Aeryth_RS09955	COG2072	flavoprotein involved in K transport
Aeryth_RS09970	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Aeryth_RS09980	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
Aeryth_RS10065	COG3180	Ammonia monooxygenase
Aeryth_RS10070	COG2326	polyphosphate kinase activity
Aeryth_RS10075	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
Aeryth_RS10080	COG2755	lipolytic protein G-D-S-L family
Aeryth_RS10085	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Aeryth_RS10090	COG3253	May function as heme-dependent peroxidase
Aeryth_RS10095	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
Aeryth_RS10100	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
Aeryth_RS10115	COG0672	)-iron permease
Aeryth_RS10125	COG0667	Aldo Keto reductase
Aeryth_RS10135	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
Aeryth_RS10150	COG1322	Protein conserved in bacteria
Aeryth_RS10170	COG0343	queuine tRNA-ribosyltransferase activity
Aeryth_RS10180	COG0644	oxidoreductase
Aeryth_RS10195	COG0237	dephospho-CoA kinase activity
Aeryth_RS10195	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Aeryth_RS10215	COG0539	negative regulation of cytoplasmic translation
Aeryth_RS10220	COG1362	aminopeptidase activity
Aeryth_RS10240	COG4981	capsule polysaccharide biosynthetic process
Aeryth_RS10245	COG0500	methyltransferase
Aeryth_RS10250	COG0438	transferase activity, transferring glycosyl groups
Aeryth_RS10275	COG1811	Na channel or pump
Aeryth_RS10320	COG0469	pyruvate kinase activity
Aeryth_RS10330	COG0067	glutamate synthase
Aeryth_RS10330	COG0069	glutamate synthase activity
Aeryth_RS10330	COG0070	glutamate synthase
Aeryth_RS10340	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
Aeryth_RS10345	COG0159	tryptophan synthase activity
Aeryth_RS10350	COG0133	tryptophan synthase activity
Aeryth_RS10355	COG0134	indole-3-glycerol-phosphate synthase activity
Aeryth_RS10395	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
Aeryth_RS10400	COG1132	(ABC) transporter
Aeryth_RS10405	COG1132	(ABC) transporter
Aeryth_RS10410	COG0107	imidazoleglycerol-phosphate synthase activity
Aeryth_RS10425	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
Aeryth_RS10430	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
Aeryth_RS10435	COG0131	Imidazoleglycerol-phosphate dehydratase
Aeryth_RS10445	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
Aeryth_RS10450	COG3135	benzoate transporter
Aeryth_RS10455	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
Aeryth_RS10465	COG0587	DNA-directed DNA polymerase activity
Aeryth_RS10510	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
Aeryth_RS10525	COG1799	cell septum assembly
Aeryth_RS10530	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
Aeryth_RS10535	COG1496	oxidoreductase activity
Aeryth_RS10540	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
Aeryth_RS10550	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
Aeryth_RS10555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Aeryth_RS10565	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
Aeryth_RS10570	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
Aeryth_RS10575	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
Aeryth_RS10580	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
Aeryth_RS10585	COG0768	penicillin binding
Aeryth_RS10595	COG0275	rRNA processing
Aeryth_RS10600	COG2001	Belongs to the MraZ family
Aeryth_RS10615	COG1231	oxidoreductase activity
Aeryth_RS10625	COG0142	geranyltranstransferase activity
Aeryth_RS10630	COG2815	serine threonine protein kinase
Aeryth_RS10630	COG0515	serine threonine protein kinase
Aeryth_RS10635	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
Aeryth_RS10660	COG1940	carbohydrate kinase activity
Aeryth_RS10665	COG1940	carbohydrate kinase activity
Aeryth_RS10680	COG1022	Amp-dependent synthetase and ligase
Aeryth_RS10710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
Aeryth_RS10720	COG1845	cytochrome c oxidase, subunit III
Aeryth_RS10730	COG0723	plastoquinol--plastocyanin reductase activity
Aeryth_RS10735	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
Aeryth_RS10740	COG1376	ErfK ybiS ycfS ynhG family protein
Aeryth_RS10750	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
Aeryth_RS10755	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
Aeryth_RS10760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Aeryth_RS10775	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Aeryth_RS10785	COG0501	Belongs to the peptidase M48B family
Aeryth_RS10805	COG0404	The glycine cleavage system catalyzes the degradation of glycine
Aeryth_RS10810	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
Aeryth_RS10830	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
Aeryth_RS10835	COG0508	dehydrogenase complex catalyzes the overall conversion of
Aeryth_RS10850	COG0321	lipoyl(octanoyl) transferase activity
Aeryth_RS10860	COG4152	abc transporter atp-binding protein
Aeryth_RS10865	COG2197	response regulator
Aeryth_RS10870	COG4585	Histidine kinase
Aeryth_RS10875	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
Aeryth_RS10895	COG0174	glutamine synthetase
Aeryth_RS10920	COG1404	Belongs to the peptidase S8 family
Aeryth_RS10940	COG2815	serine threonine protein kinase
Aeryth_RS10940	COG0515	serine threonine protein kinase
Aeryth_RS10950	COG2133	pyrroloquinoline quinone binding
Aeryth_RS10965	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
Aeryth_RS10980	COG1063	alcohol dehydrogenase
Aeryth_RS11010	COG2826	transposase and inactivated derivatives, IS30 family
Aeryth_RS11045	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Aeryth_RS11060	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
Aeryth_RS11070	COG3012	SEC-C Motif Domain Protein
Aeryth_RS11075	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
Aeryth_RS11075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Aeryth_RS11080	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
Aeryth_RS11115	COG2119	membrane
Aeryth_RS11120	COG3022	response to hydroperoxide
Aeryth_RS11135	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
Aeryth_RS11170	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
Aeryth_RS11185	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
Aeryth_RS11230	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Aeryth_RS11270	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
Aeryth_RS11275	COG0571	ribonuclease III activity
Aeryth_RS11280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
Aeryth_RS11290	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
Aeryth_RS11295	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
Aeryth_RS11300	COG0742	ribosomal rna small subunit methyltransferase
Aeryth_RS11305	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
Aeryth_RS11310	COG1461	Dihydroxyacetone kinase
Aeryth_RS11315	COG0227	Belongs to the bacterial ribosomal protein bL28 family
Aeryth_RS11320	COG0154	amidase activity
Aeryth_RS11340	COG1181	Belongs to the D-alanine--D-alanine ligase family
Aeryth_RS11345	COG0626	cystathionine gamma-synthase activity
Aeryth_RS11350	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
Aeryth_RS11365	COG0066	3-isopropylmalate dehydratase activity
Aeryth_RS11370	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
Aeryth_RS11375	COG1414	Transcriptional regulator
Aeryth_RS11405	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
Aeryth_RS11435	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
Aeryth_RS11435	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
Aeryth_RS11440	COG0179	Fumarylacetoacetate (FAA) hydrolase
Aeryth_RS11445	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
Aeryth_RS11455	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Aeryth_RS11460	COG1381	Involved in DNA repair and RecF pathway recombination
Aeryth_RS11470	COG2755	lipolytic protein G-D-S-L family
Aeryth_RS11485	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS11495	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
Aeryth_RS11500	COG0435	Glutathione S-transferase
Aeryth_RS11505	COG1414	Transcriptional regulator
Aeryth_RS11530	COG0714	Associated with various cellular activities
Aeryth_RS11555	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
Aeryth_RS11555	COG1796	DNA polymerase
Aeryth_RS11560	COG1254	Belongs to the acylphosphatase family
Aeryth_RS11565	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
Aeryth_RS11580	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
Aeryth_RS11590	COG0537	adenosine 5'-monophosphoramidase activity
Aeryth_RS11595	COG0484	heat shock protein binding
Aeryth_RS11600	COG1420	regulation of RNA biosynthetic process
Aeryth_RS11615	COG3942	CHAP domain
Aeryth_RS11615	COG1388	LysM domain
Aeryth_RS11625	COG1022	Amp-dependent synthetase and ligase
Aeryth_RS11635	COG0481	GTPase activity
Aeryth_RS11645	COG0268	Binds directly to 16S ribosomal RNA
Aeryth_RS11660	COG0658	competence protein
Aeryth_RS11660	COG2333	competence protein COMEC
Aeryth_RS11665	COG1555	photosystem II stabilization
Aeryth_RS11665	COG1596	polysaccharide export
Aeryth_RS11675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
Aeryth_RS11680	COG1307	EDD domain protein, DegV family
Aeryth_RS11685	COG0495	leucyl-tRNA aminoacylation
Aeryth_RS11705	COG0569	domain protein
Aeryth_RS11710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
Aeryth_RS11715	COG1216	Glycosyl transferase, family 2
Aeryth_RS11720	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
Aeryth_RS11725	COG1216	Glycosyl transferase, family 2
Aeryth_RS11740	COG0438	transferase activity, transferring glycosyl groups
Aeryth_RS11780	COG2089	acid synthase
Aeryth_RS11785	COG1083	cytidylyl-transferase
Aeryth_RS11800	COG3590	peptidase
Aeryth_RS11805	COG2814	Major facilitator Superfamily
Aeryth_RS11835	COG0454	-acetyltransferase
Aeryth_RS11845	COG0477	Major facilitator Superfamily
Aeryth_RS11910	COG1120	ATPase activity
Aeryth_RS11915	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Aeryth_RS11920	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Aeryth_RS11950	COG0799	negative regulation of ribosome biogenesis
Aeryth_RS11955	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
Aeryth_RS11960	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
Aeryth_RS11970	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
Aeryth_RS11975	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Aeryth_RS11980	COG0211	Belongs to the bacterial ribosomal protein bL27 family
Aeryth_RS11985	COG0261	This protein binds to 23S rRNA in the presence of protein L20
Aeryth_RS11990	COG1530	ribonuclease E activity
Aeryth_RS12000	COG2807	transmembrane transport
Aeryth_RS12025	COG0105	UTP biosynthetic process
Aeryth_RS12030	COG0366	Alpha amylase catalytic
Aeryth_RS12070	COG0285	dihydrofolate synthase activity
Aeryth_RS12075	COG2409	Drug exporters of the RND superfamily
Aeryth_RS12105	COG0525	valine-tRNA ligase activity
Aeryth_RS12110	COG3268	Saccharopine dehydrogenase
Aeryth_RS12115	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
Aeryth_RS12120	COG0740	serine-type endopeptidase activity
Aeryth_RS12125	COG0740	serine-type endopeptidase activity
Aeryth_RS12130	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS12150	COG0673	inositol 2-dehydrogenase activity
Aeryth_RS12160	COG0673	inositol 2-dehydrogenase activity
Aeryth_RS12190	COG3962	Belongs to the TPP enzyme family
Aeryth_RS12195	COG3718	enzyme involved in inositol metabolism
Aeryth_RS12205	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
Aeryth_RS12210	COG1082	Xylose isomerase domain protein TIM barrel
Aeryth_RS12215	COG2188	Transcriptional regulator
Aeryth_RS12235	COG0544	peptidyl-prolyl cis-trans isomerase activity
Aeryth_RS12245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Aeryth_RS12265	COG0564	pseudouridine synthase activity
Aeryth_RS12270	COG1160	GTP binding
Aeryth_RS12280	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Aeryth_RS12295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
Aeryth_RS12320	COG0494	nUDIX hydrolase
Aeryth_RS12325	COG0504	CTP synthase activity
Aeryth_RS12340	COG0497	DNA recombination
Aeryth_RS12345	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
Aeryth_RS12360	COG0647	UMP catabolic process
Aeryth_RS12400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Aeryth_RS12405	COG0521	Mo-molybdopterin cofactor biosynthetic process
Aeryth_RS12410	COG0315	cyclic pyranopterin monophosphate synthase activity
Aeryth_RS12425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
Aeryth_RS12445	COG1970	mechanosensitive ion channel activity
Aeryth_RS12470	COG2133	pyrroloquinoline quinone binding
Aeryth_RS12485	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
Aeryth_RS12530	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Aeryth_RS12540	COG0702	epimerase
Aeryth_RS12550	COG0415	Belongs to the DNA photolyase family
Aeryth_RS12570	COG0259	pyridoxamine-phosphate oxidase activity
Aeryth_RS12595	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Aeryth_RS12610	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Aeryth_RS12630	COG0488	(ABC) transporter
Aeryth_RS12660	COG0328	RNA-DNA hybrid ribonuclease activity
Aeryth_RS12690	COG0012	GTP binding
Aeryth_RS12695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
Aeryth_RS12720	COG0405	Gamma-glutamyltransferase
Aeryth_RS12735	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
Aeryth_RS12740	COG1570	exodeoxyribonuclease VII activity
Aeryth_RS12745	COG1722	exodeoxyribonuclease VII activity
Aeryth_RS12785	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
Aeryth_RS12805	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
Aeryth_RS12805	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
Aeryth_RS12810	COG0114	fumarate hydratase activity
Aeryth_RS12820	COG3842	ATPase activity
Aeryth_RS12840	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
Aeryth_RS12845	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
Aeryth_RS12860	COG1331	Highly conserved protein containing a thioredoxin domain
Aeryth_RS12875	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Aeryth_RS12885	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
Aeryth_RS12895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
Aeryth_RS12905	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
Aeryth_RS12955	COG2755	lipolytic protein G-D-S-L family
Aeryth_RS12970	COG0220	tRNA (guanine-N7-)-methyltransferase activity
Aeryth_RS12985	COG2233	PERMEase
Aeryth_RS13000	COG0179	Fumarylacetoacetate (FAA) hydrolase
Aeryth_RS13015	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
Aeryth_RS13045	COG1643	Atp-dependent helicase
Aeryth_RS13060	COG1121	(ABC) transporter
Aeryth_RS13070	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
Aeryth_RS13090	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
Aeryth_RS13150	COG1301	dicarboxylic acid transport
Aeryth_RS13155	COG3290	protein histidine kinase activity
Aeryth_RS13160	COG4565	transcriptional regulatory protein
Aeryth_RS13175	COG0148	phosphopyruvate hydratase activity
Aeryth_RS13220	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
Aeryth_RS13230	COG2252	PERMEase
Aeryth_RS13250	COG2814	Major facilitator Superfamily
Aeryth_RS13255	COG3384	dioxygenase
Aeryth_RS13260	COG1278	Cold shock
Aeryth_RS13265	COG1295	ribonuclease BN
Aeryth_RS13275	COG0318	PFAM AMP-dependent synthetase and ligase
Aeryth_RS13285	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
Aeryth_RS13345	COG1012	belongs to the aldehyde dehydrogenase family
Aeryth_RS13360	COG1131	(ABC) transporter
Aeryth_RS13365	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
Aeryth_RS13385	COG0456	acetyltransferase
Aeryth_RS13390	COG0456	acetyltransferase
Aeryth_RS13390	COG1214	PFAM Peptidase M22, glycoprotease
Aeryth_RS13395	COG2826	transposase and inactivated derivatives, IS30 family
Aeryth_RS13400	COG0802	atpase or kinase
Aeryth_RS13410	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
Aeryth_RS13420	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
Aeryth_RS13425	COG1072	(Pantothenic acid kinase))
Aeryth_RS13435	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
Aeryth_RS13440	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
Aeryth_RS13445	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
Aeryth_RS13450	COG0372	Belongs to the citrate synthase family
Aeryth_RS13470	COG0101	tRNA pseudouridine synthase activity
Aeryth_RS13480	COG2890	protein-(glutamine-N5) methyltransferase activity
Aeryth_RS13490	COG0203	ribosomal protein L17
Aeryth_RS13495	COG0202	RNA polymerase activity
Aeryth_RS13500	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
Aeryth_RS13505	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
Aeryth_RS13510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Aeryth_RS13515	COG0257	Belongs to the bacterial ribosomal protein bL36 family
Aeryth_RS13520	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
Aeryth_RS13525	COG1522	sequence-specific DNA binding
Aeryth_RS13530	COG1834	amidinotransferase
Aeryth_RS13550	COG0563	adenylate kinase activity
Aeryth_RS13565	COG1841	ribosomal large subunit assembly
Aeryth_RS13570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
Aeryth_RS13575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
Aeryth_RS13580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
Aeryth_RS13585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
Aeryth_RS13590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
Aeryth_RS13595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Aeryth_RS13600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
Aeryth_RS13605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
Aeryth_RS13610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
Aeryth_RS13620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
Aeryth_RS13625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
Aeryth_RS13630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
Aeryth_RS13635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
Aeryth_RS13640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Aeryth_RS13645	COG0089	rRNA binding
Aeryth_RS13650	COG0088	Forms part of the polypeptide exit tunnel
Aeryth_RS13655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
Aeryth_RS13660	COG0051	transcription antitermination factor activity, RNA binding
Aeryth_RS13670	COG0697	spore germination
Aeryth_RS13675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Aeryth_RS13680	COG0546	phosphoglycolate phosphatase activity
Aeryth_RS13685	COG2313	pseudouridylate synthase activity
Aeryth_RS13695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
Aeryth_RS13700	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
Aeryth_RS13705	COG0049	tRNA binding
Aeryth_RS13710	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
Aeryth_RS13720	COG0446	pyridine nucleotide-disulphide oxidoreductase
Aeryth_RS13740	COG3764	Sortase (surface protein transpeptidase)
Aeryth_RS13765	COG3185	4-Hydroxyphenylpyruvate dioxygenase
Aeryth_RS13785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
Aeryth_RS13825	COG1302	Protein conserved in bacteria
Aeryth_RS13830	COG1595	DNA-templated transcription, initiation
Aeryth_RS13885	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
Aeryth_RS13890	COG1316	TRANSCRIPTIONal
Aeryth_RS13900	COG0287	Prephenate dehydrogenase
Aeryth_RS13900	COG1605	Chorismate mutase
Aeryth_RS13910	COG0470	DNA polymerase III
Aeryth_RS13920	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
Aeryth_RS13920	COG1754	DNA topoisomerase type I activity
Aeryth_RS13925	COG2264	protein methyltransferase activity
Aeryth_RS13930	COG1366	Belongs to the anti-sigma-factor antagonist family
Aeryth_RS13935	COG1205	dead DEAH box helicase
Aeryth_RS13935	COG1111	helicase
Aeryth_RS13990	COG0489	protein tyrosine kinase activity
Aeryth_RS13995	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Aeryth_RS14010	COG3275	phosphorelay sensor kinase activity
Aeryth_RS14025	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
Aeryth_RS14030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
Aeryth_RS14040	COG1045	serine acetyltransferase
Aeryth_RS14080	COG0110	maltose O-acetyltransferase activity
Aeryth_RS14095	COG1268	BioY protein
Aeryth_RS14100	COG1122	ATPase activity
Aeryth_RS14120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Aeryth_RS14130	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
Aeryth_RS14135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Aeryth_RS14150	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
Aeryth_RS14160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
Aeryth_RS14185	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
Aeryth_RS14210	COG0662	Cupin 2, conserved barrel domain protein
Aeryth_RS14210	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
Aeryth_RS14225	COG0489	protein tyrosine kinase activity
Aeryth_RS14235	COG0354	folic acid binding
Aeryth_RS14240	COG4044	May play a role in the intracellular transport of hydrophobic ligands
Aeryth_RS14245	COG1490	D-aminoacyl-tRNA deacylase activity
Aeryth_RS14250	COG1316	TRANSCRIPTIONal
Aeryth_RS14280	COG3479	Phenolic acid decarboxylase
Aeryth_RS14300	COG0745	RESPONSE REGULATOR receiver
Aeryth_RS14310	COG0456	acetyltransferase
Aeryth_RS14310	COG0454	-acetyltransferase
Aeryth_RS14315	COG0657	acetylesterase activity
Aeryth_RS14320	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
Aeryth_RS14350	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
Aeryth_RS14355	COG0306	phosphate transporter
Aeryth_RS14405	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Aeryth_RS14415	COG1116	anion transmembrane transporter activity
Aeryth_RS14420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
Aeryth_RS14425	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS14440	COG0297	glycogen (starch) synthase activity
Aeryth_RS14450	COG2072	flavoprotein involved in K transport
Aeryth_RS14495	COG3835	regulator
Aeryth_RS14505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
Aeryth_RS14550	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
Aeryth_RS14555	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS14565	COG1064	alcohol dehydrogenase
Aeryth_RS14570	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
Aeryth_RS14575	COG1063	alcohol dehydrogenase
Aeryth_RS14580	COG1492	cobalamin metabolic process
Aeryth_RS14590	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
Aeryth_RS14595	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
Aeryth_RS14605	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
Aeryth_RS14605	COG1648	precorrin-2 dehydrogenase activity
Aeryth_RS14610	COG1797	cobyrinic acid a,c-diamide synthase activity
Aeryth_RS14615	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
Aeryth_RS14665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Aeryth_RS14680	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
Aeryth_RS14700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
Aeryth_RS14735	COG0477	Major facilitator Superfamily
Aeryth_RS14750	COG0702	epimerase
Aeryth_RS14755	COG0739	heme binding
Aeryth_RS14765	COG3629	intracellular signal transduction
Aeryth_RS14765	COG3903	Transcriptional regulator
Aeryth_RS14785	COG1024	Enoyl-CoA hydratase
Aeryth_RS14795	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS14815	COG2267	carboxylic ester hydrolase activity
Aeryth_RS14830	COG2850	peptidyl-arginine hydroxylation
Aeryth_RS14855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
Aeryth_RS14885	COG4133	protoheme IX ABC transporter activity
Aeryth_RS14935	COG3486	L-lysine 6-monooxygenase (NADPH) activity
Aeryth_RS14940	COG0076	glutamate decarboxylase activity
Aeryth_RS14950	COG1674	ftsk spoiiie
Aeryth_RS15010	COG1404	Belongs to the peptidase S8 family
Aeryth_RS15035	COG1966	Carbon starvation protein
Aeryth_RS15045	COG0531	amino acid
Aeryth_RS15050	COG0589	response to stress
Aeryth_RS15065	COG0433	COG0433 Predicted ATPase
Aeryth_RS15100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
Aeryth_RS15110	COG0589	response to stress
Aeryth_RS15120	COG2205	protein histidine kinase activity
Aeryth_RS15155	COG0277	FAD linked oxidase domain protein
Aeryth_RS15165	COG1960	acyl-CoA dehydrogenase activity
Aeryth_RS15175	COG1942	4-Oxalocrotonate Tautomerase
Aeryth_RS15185	COG0706	membrane insertase activity
Aeryth_RS15200	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
Aeryth_RS15200	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
Aeryth_RS15220	COG0318	PFAM AMP-dependent synthetase and ligase
Aeryth_RS15240	COG0431	NADPH-dependent FMN reductase
Aeryth_RS15245	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
Aeryth_RS15255	COG0590	tRNA wobble adenosine to inosine editing
Aeryth_RS15260	COG2160	L-arabinose isomerase activity
Aeryth_RS15275	COG1609	Transcriptional regulator
Aeryth_RS15280	COG1172	Belongs to the binding-protein-dependent transport system permease family
Aeryth_RS15285	COG1172	Belongs to the binding-protein-dependent transport system permease family
Aeryth_RS15295	COG1879	ABC-type sugar transport system periplasmic component
Aeryth_RS15300	COG0277	FAD linked oxidase domain protein
Aeryth_RS15305	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
Aeryth_RS15340	COG0523	cobalamin synthesis protein
Aeryth_RS15355	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
Aeryth_RS15360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
Aeryth_RS15370	COG5001	Diguanylate cyclase
Aeryth_RS15395	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
Aeryth_RS15415	COG3706	GGDEF domain
Aeryth_RS15425	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
Aeryth_RS15435	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
Aeryth_RS15440	COG3387	PFAM Glycoside hydrolase 15-related
Aeryth_RS15450	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
Aeryth_RS15455	COG2814	Major facilitator Superfamily
Aeryth_RS15495	COG2095	MarC family integral membrane protein
Aeryth_RS15550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
Aeryth_RS15555	COG0598	Magnesium transport protein CorA
Aeryth_RS15595	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
Aeryth_RS15645	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
Aeryth_RS15665	COG1215	transferase activity, transferring glycosyl groups
Aeryth_RS15675	COG0673	inositol 2-dehydrogenase activity
Aeryth_RS15685	COG0667	Aldo Keto reductase
Aeryth_RS15690	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Aeryth_RS15695	COG0489	protein tyrosine kinase activity
Aeryth_RS15710	COG2827	Endonuclease containing a URI domain
Aeryth_RS15720	COG4608	Belongs to the ABC transporter superfamily
Aeryth_RS15730	COG0747	negative chemotaxis
Aeryth_RS15805	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
Aeryth_RS15810	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
Aeryth_RS15835	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
Aeryth_RS15845	COG2124	cytochrome p450
Aeryth_RS15865	COG2124	cytochrome p450
Aeryth_RS15875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
Aeryth_RS15880	COG0667	Aldo Keto reductase
Aeryth_RS15885	COG1819	glycosyl
Aeryth_RS15890	COG2124	cytochrome p450
Aeryth_RS15935	COG0657	acetylesterase activity
Aeryth_RS15950	COG0235	Class ii aldolase
Aeryth_RS15995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
Aeryth_RS16000	COG3046	protein related to deoxyribodipyrimidine photolyase
Aeryth_RS16005	COG0604	alcohol dehydrogenase
Aeryth_RS16005	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS16005	COG3321	synthase
Aeryth_RS16020	COG0561	phosphatase activity
Aeryth_RS16025	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
Aeryth_RS16040	COG2354	Protein conserved in bacteria
Aeryth_RS16075	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
Aeryth_RS16085	COG1260	myo-inositol-1-phosphate synthase
Aeryth_RS16090	COG1597	lipid kinase activity
Aeryth_RS16095	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
Aeryth_RS16130	COG0667	Aldo Keto reductase
Aeryth_RS16150	COG0366	Alpha amylase catalytic
Aeryth_RS16155	COG0366	Alpha amylase catalytic
Aeryth_RS16165	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
Aeryth_RS16170	COG2235	arginine
Aeryth_RS16195	COG0425	Belongs to the sulfur carrier protein TusA family
Aeryth_RS16195	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
Aeryth_RS16200	COG0776	regulation of translation
Aeryth_RS16205	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
Aeryth_RS16280	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
Aeryth_RS16305	COG0477	Major facilitator Superfamily
Aeryth_RS16315	COG0584	glycerophosphoryl diester phosphodiesterase
Aeryth_RS16320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
Aeryth_RS16330	COG1739	Uncharacterized protein family UPF0029
Aeryth_RS16355	COG0693	protein deglycase activity
Aeryth_RS16370	COG1136	(ABC) transporter
Aeryth_RS16380	COG0604	alcohol dehydrogenase
Aeryth_RS16400	COG0589	response to stress
Aeryth_RS16415	COG1028	Short-chain dehydrogenase reductase Sdr
Aeryth_RS16425	COG0596	Alpha beta hydrolase
Aeryth_RS16475	COG1716	ATPase activity
Aeryth_RS16480	COG1716	ATPase activity
Aeryth_RS16495	COG0768	penicillin binding
Aeryth_RS16500	COG0515	serine threonine protein kinase
Aeryth_RS16520	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
Aeryth_RS16545	COG1233	COG1233 Phytoene dehydrogenase and related
Aeryth_RS16550	COG2226	methyltransferase
Aeryth_RS16575	COG1024	Enoyl-CoA hydratase
Aeryth_RS16590	COG2200	EAL domain
Aeryth_RS16590	COG2199	diguanylate cyclase activity
Aeryth_RS16610	COG0515	serine threonine protein kinase
Aeryth_RS16610	COG2815	serine threonine protein kinase
Aeryth_RS16625	COG0702	epimerase
Aeryth_RS16630	COG0531	amino acid
Aeryth_RS16635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
Aeryth_RS16640	COG1120	ATPase activity
Aeryth_RS16645	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Aeryth_RS16650	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
Aeryth_RS16670	COG1024	Enoyl-CoA hydratase
Aeryth_RS16670	COG1250	3-hydroxyacyl-CoA dehydrogenase
Aeryth_RS16675	COG0183	Belongs to the thiolase family
Aeryth_RS16695	COG1804	L-carnitine dehydratase bile acid-inducible protein F
Aeryth_RS16730	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
Aeryth_RS16755	COG0765	amino acid transport
Aeryth_RS16760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
Aeryth_RS16780	COG0446	pyridine nucleotide-disulphide oxidoreductase
Aeryth_RS16780	COG1902	pentaerythritol trinitrate reductase activity
Aeryth_RS16785	COG2130	NADP-dependent
Aeryth_RS16795	COG2261	transglycosylase associated protein
Aeryth_RS16805	COG0384	phenazine biosynthesis protein PhzF
Aeryth_RS16835	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
Aeryth_RS16855	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
Aeryth_RS16885	COG4585	Histidine kinase
Aeryth_RS16890	COG2197	response regulator
Aeryth_RS16925	COG1937	Protein conserved in bacteria
Aeryth_RS16945	COG2372	response to copper ion
Aeryth_RS16945	COG1276	copper resistance
Aeryth_RS16950	COG2847	Copper chaperone PCu(A)C
Aeryth_RS16955	COG2837	iron assimilation
Aeryth_RS17000	COG1132	(ABC) transporter
Aeryth_RS17005	COG0596	Alpha beta hydrolase
Aeryth_RS17020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
Aeryth_RS17025	COG0586	Pfam SNARE associated Golgi protein
Aeryth_RS17040	COG0739	heme binding
Aeryth_RS17045	COG0633	Ferredoxin
Aeryth_RS17045	COG3217	Mosc domain protein beta barrel domain protein
Aeryth_RS17050	COG0305	Participates in initiation and elongation during chromosome replication
Aeryth_RS17070	COG0359	binds to the 23S rRNA
Aeryth_RS17075	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
Aeryth_RS17080	COG0629	single-stranded DNA binding
Aeryth_RS17085	COG0360	Binds together with S18 to 16S ribosomal RNA
Aeryth_RS17100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
Aeryth_RS17110	COG0667	Aldo Keto reductase
Aeryth_RS17125	COG1305	Transglutaminase-like
Aeryth_RS17160	COG0492	ferredoxin-NADP+ reductase activity
Aeryth_RS17165	COG3118	belongs to the thioredoxin family
Aeryth_RS17175	COG1192	Involved in chromosome partitioning
Aeryth_RS17180	COG0357	Ribosomal RNA small subunit methyltransferase G
Aeryth_RS17190	COG0706	membrane insertase activity
Aeryth_RS17195	COG0594	ribonuclease P activity