locus-tag	class	description
GEV26_RS00235	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GEV26_RS00240	COG0592	DNA-directed DNA polymerase activity
GEV26_RS00245	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GEV26_RS00250	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GEV26_RS00255	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
GEV26_RS00265	COG0187	DNA topoisomerase II activity
GEV26_RS00270	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEV26_RS00330	COG0601	transmembrane transport
GEV26_RS00335	COG4166	transmembrane transport
GEV26_RS00350	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GEV26_RS00365	COG1024	Enoyl-CoA hydratase
GEV26_RS00370	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GEV26_RS00375	COG0705	Rhomboid family
GEV26_RS00390	COG0515	serine threonine protein kinase
GEV26_RS00395	COG0768	penicillin binding
GEV26_RS00410	COG1716	ATPase activity
GEV26_RS00415	COG1716	ATPase activity
GEV26_RS00435	COG2814	Major facilitator Superfamily
GEV26_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS00470	COG0693	protein deglycase activity
GEV26_RS00500	COG0477	Major facilitator Superfamily
GEV26_RS00515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV26_RS00540	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GEV26_RS00545	COG0776	regulation of translation
GEV26_RS00555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GEV26_RS00600	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV26_RS00615	COG1597	lipid kinase activity
GEV26_RS00620	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GEV26_RS00625	COG0561	phosphatase activity
GEV26_RS00630	COG1733	regulation of RNA biosynthetic process
GEV26_RS00635	COG0667	Aldo Keto reductase
GEV26_RS00640	COG0432	Pfam Uncharacterised protein family UPF0047
GEV26_RS00655	COG3321	synthase
GEV26_RS00655	COG0604	alcohol dehydrogenase
GEV26_RS00655	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS00660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GEV26_RS00715	COG0489	protein tyrosine kinase activity
GEV26_RS00725	COG1088	dTDP-glucose 4,6-dehydratase activity
GEV26_RS00750	COG0477	Major facilitator Superfamily
GEV26_RS00825	COG2814	Major facilitator Superfamily
GEV26_RS00835	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS00840	COG2827	Endonuclease containing a URI domain
GEV26_RS00850	COG1802	Transcriptional regulator
GEV26_RS00860	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS00865	COG2079	MmgE PrpD family protein
GEV26_RS00875	COG3842	ATPase activity
GEV26_RS00895	COG0183	Belongs to the thiolase family
GEV26_RS00900	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
GEV26_RS00910	COG2301	Belongs to the HpcH HpaI aldolase family
GEV26_RS00915	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS00920	COG1024	Enoyl-CoA hydratase
GEV26_RS00930	COG3537	Alpha-1,2-mannosidase
GEV26_RS00935	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GEV26_RS00965	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV26_RS00970	COG4251	negative regulation of phosphorylation
GEV26_RS00975	COG2770	Histidine kinase
GEV26_RS00975	COG2208	phosphoserine phosphatase activity
GEV26_RS00980	COG1793	dna ligase
GEV26_RS01015	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
GEV26_RS01020	COG0110	maltose O-acetyltransferase activity
GEV26_RS01025	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS01040	COG0583	DNA-binding transcription factor activity
GEV26_RS01050	COG2409	Drug exporters of the RND superfamily
GEV26_RS01075	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GEV26_RS01080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
GEV26_RS01085	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GEV26_RS01095	COG0037	tRNA processing
GEV26_RS01095	COG0590	tRNA wobble adenosine to inosine editing
GEV26_RS01100	COG0604	alcohol dehydrogenase
GEV26_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS01100	COG3321	synthase
GEV26_RS01105	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS01115	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS01125	COG1072	(Pantothenic acid kinase))
GEV26_RS01145	COG1309	transcriptional regulator
GEV26_RS01165	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV26_RS01170	COG0444	Belongs to the ABC transporter superfamily
GEV26_RS01185	COG0477	Major facilitator Superfamily
GEV26_RS01225	COG0667	Aldo Keto reductase
GEV26_RS01240	COG0667	Aldo Keto reductase
GEV26_RS01265	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GEV26_RS01290	COG3263	regulation of cellular component size
GEV26_RS01305	COG0433	COG0433 Predicted ATPase
GEV26_RS01340	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GEV26_RS01395	COG0142	geranyltranstransferase activity
GEV26_RS01435	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS01470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GEV26_RS01485	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV26_RS01500	COG1408	metallophosphoesterase
GEV26_RS01510	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV26_RS01545	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV26_RS01565	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GEV26_RS01595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV26_RS01600	COG2197	response regulator
GEV26_RS01605	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV26_RS01615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GEV26_RS01630	COG3275	phosphorelay sensor kinase activity
GEV26_RS01635	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
GEV26_RS01640	COG1122	ATPase activity
GEV26_RS01645	COG1268	BioY protein
GEV26_RS01715	COG1205	dead DEAH box helicase
GEV26_RS01715	COG1111	helicase
GEV26_RS01720	COG1366	Belongs to the anti-sigma-factor antagonist family
GEV26_RS01725	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GEV26_RS01730	COG2890	protein-(glutamine-N5) methyltransferase activity
GEV26_RS01745	COG1754	DNA topoisomerase type I activity
GEV26_RS01745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GEV26_RS01760	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
GEV26_RS01775	COG0287	Prephenate dehydrogenase
GEV26_RS01775	COG1605	Chorismate mutase
GEV26_RS01795	COG2409	Drug exporters of the RND superfamily
GEV26_RS01805	COG1253	flavin adenine dinucleotide binding
GEV26_RS01815	COG0515	serine threonine protein kinase
GEV26_RS01825	COG2223	nitrite transmembrane transporter activity
GEV26_RS01830	COG3764	Sortase (surface protein transpeptidase)
GEV26_RS01835	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GEV26_RS01850	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV26_RS01870	COG1597	lipid kinase activity
GEV26_RS01885	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GEV26_RS01890	COG0151	Belongs to the GarS family
GEV26_RS01895	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GEV26_RS01905	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GEV26_RS01910	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS01920	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEV26_RS01925	COG0047	phosphoribosylformylglycinamidine synthase activity
GEV26_RS01965	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GEV26_RS01975	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV26_RS01975	COG2755	lipolytic protein G-D-S-L family
GEV26_RS01990	COG1902	pentaerythritol trinitrate reductase activity
GEV26_RS01995	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GEV26_RS02030	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GEV26_RS02055	COG1846	Transcriptional regulator
GEV26_RS02060	COG4221	oxidoreductase activity
GEV26_RS02065	COG1309	transcriptional regulator
GEV26_RS02085	COG0778	Nitroreductase
GEV26_RS02110	COG1125	glycine betaine transport
GEV26_RS02110	COG0517	IMP dehydrogenase activity
GEV26_RS02115	COG1174	glycine betaine transport
GEV26_RS02120	COG1174	glycine betaine transport
GEV26_RS02140	COG2197	response regulator
GEV26_RS02145	COG2267	carboxylic ester hydrolase activity
GEV26_RS02150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEV26_RS02175	COG2124	cytochrome p450
GEV26_RS02200	COG1793	dna ligase
GEV26_RS02215	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GEV26_RS02225	COG4221	oxidoreductase activity
GEV26_RS02235	COG1295	ribonuclease BN
GEV26_RS02240	COG0723	plastoquinol--plastocyanin reductase activity
GEV26_RS02255	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS02260	COG2890	protein-(glutamine-N5) methyltransferase activity
GEV26_RS02305	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GEV26_RS02315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV26_RS02320	COG0463	Glycosyl transferase, family 2
GEV26_RS02325	COG1216	Glycosyl transferase, family 2
GEV26_RS02335	COG2755	lipolytic protein G-D-S-L family
GEV26_RS02335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV26_RS02340	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV26_RS02340	COG2755	lipolytic protein G-D-S-L family
GEV26_RS02355	COG1215	transferase activity, transferring glycosyl groups
GEV26_RS02375	COG0531	amino acid
GEV26_RS02385	COG2186	Transcriptional regulator
GEV26_RS02395	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS02400	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS02405	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GEV26_RS02420	COG0596	Alpha beta hydrolase
GEV26_RS02435	COG0640	Transcriptional regulator
GEV26_RS02460	COG1316	TRANSCRIPTIONal
GEV26_RS02470	COG1129	ABC transporter
GEV26_RS02485	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS02495	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS02500	COG4032	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain
GEV26_RS02500	COG0028	Belongs to the TPP enzyme family
GEV26_RS02530	COG1024	Enoyl-CoA hydratase
GEV26_RS02555	COG0069	glutamate synthase activity
GEV26_RS02560	COG2205	protein histidine kinase activity
GEV26_RS02600	COG0477	Major facilitator Superfamily
GEV26_RS02610	COG0306	phosphate transporter
GEV26_RS02615	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
GEV26_RS02630	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
GEV26_RS02645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GEV26_RS02650	COG0657	acetylesterase activity
GEV26_RS02655	COG0456	acetyltransferase
GEV26_RS02665	COG0745	RESPONSE REGULATOR receiver
GEV26_RS02700	COG1490	D-aminoacyl-tRNA deacylase activity
GEV26_RS02705	COG4044	May play a role in the intracellular transport of hydrophobic ligands
GEV26_RS02710	COG0354	folic acid binding
GEV26_RS02725	COG1482	cell wall glycoprotein biosynthetic process
GEV26_RS02730	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
GEV26_RS02730	COG0662	Cupin 2, conserved barrel domain protein
GEV26_RS02770	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
GEV26_RS02795	COG1217	gtp-binding protein TYPA
GEV26_RS02800	COG1846	Transcriptional regulator
GEV26_RS02805	COG0477	Major facilitator Superfamily
GEV26_RS02815	COG0438	transferase activity, transferring glycosyl groups
GEV26_RS02830	COG0588	phosphoglycerate mutase activity
GEV26_RS02860	COG1329	Transcriptional regulator
GEV26_RS02865	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
GEV26_RS02880	COG0215	cysteine-tRNA ligase activity
GEV26_RS02905	COG0535	radical SAM domain protein
GEV26_RS02930	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
GEV26_RS02935	COG0778	Nitroreductase
GEV26_RS02935	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GEV26_RS02940	COG0391	Required for morphogenesis under gluconeogenic growth conditions
GEV26_RS02950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS02955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
GEV26_RS02960	COG1116	anion transmembrane transporter activity
GEV26_RS02965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV26_RS03005	COG0076	glutamate decarboxylase activity
GEV26_RS03035	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
GEV26_RS03040	COG0628	permease
GEV26_RS03045	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GEV26_RS03050	COG2223	nitrite transmembrane transporter activity
GEV26_RS03060	COG0686	Belongs to the AlaDH PNT family
GEV26_RS03095	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
GEV26_RS03125	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
GEV26_RS03130	COG1278	Cold shock
GEV26_RS03160	COG0459	protein refolding
GEV26_RS03165	COG3842	ATPase activity
GEV26_RS03170	COG4208	sulfate ABC transporter
GEV26_RS03175	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
GEV26_RS03180	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
GEV26_RS03200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GEV26_RS03205	COG0077	Prephenate dehydratase
GEV26_RS03205	COG1605	Chorismate mutase
GEV26_RS03210	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GEV26_RS03215	COG0180	Tryptophanyl-tRNA synthetase
GEV26_RS03225	COG0583	DNA-binding transcription factor activity
GEV26_RS03235	COG1053	succinate dehydrogenase
GEV26_RS03240	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GEV26_RS03260	COG1473	amidohydrolase
GEV26_RS03260	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GEV26_RS03265	COG1744	ABC transporter substrate-binding protein PnrA-like
GEV26_RS03270	COG3845	ABC transporter
GEV26_RS03275	COG4603	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS03280	COG1079	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS03305	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV26_RS03310	COG0183	Belongs to the thiolase family
GEV26_RS03320	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS03330	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
GEV26_RS03335	COG1920	GTP binding
GEV26_RS03355	COG0737	Belongs to the 5'-nucleotidase family
GEV26_RS03370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV26_RS03375	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GEV26_RS03405	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
GEV26_RS03410	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV26_RS03430	COG2385	sporulation resulting in formation of a cellular spore
GEV26_RS03445	COG4770	biotin carboxylase activity
GEV26_RS03450	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS03460	COG0515	serine threonine protein kinase
GEV26_RS03480	COG0424	maF-like protein
GEV26_RS03500	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV26_RS03515	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GEV26_RS03540	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
GEV26_RS03550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV26_RS03555	COG1611	Belongs to the LOG family
GEV26_RS03560	COG0519	Catalyzes the synthesis of GMP from XMP
GEV26_RS03575	COG1024	Enoyl-CoA hydratase
GEV26_RS03605	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GEV26_RS03615	COG0488	(ABC) transporter
GEV26_RS03620	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV26_RS03630	COG2239	Acts as a magnesium transporter
GEV26_RS03655	COG0657	acetylesterase activity
GEV26_RS03665	COG1090	epimerase
GEV26_RS03675	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS03685	COG2030	dehydratase
GEV26_RS03700	COG0613	PHP domain protein
GEV26_RS03715	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
GEV26_RS03725	COG4221	oxidoreductase activity
GEV26_RS03755	COG1309	transcriptional regulator
GEV26_RS03775	COG0210	DNA helicase
GEV26_RS03795	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
GEV26_RS03825	COG3480	Lon protease (S16) C-terminal proteolytic domain
GEV26_RS03835	COG1615	UPF0182 protein
GEV26_RS03885	COG1231	oxidoreductase activity
GEV26_RS03905	COG0531	amino acid
GEV26_RS03925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GEV26_RS03950	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GEV26_RS03960	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS03965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV26_RS03970	COG2072	flavoprotein involved in K transport
GEV26_RS03975	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS03980	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS03985	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS03990	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS04005	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS04015	COG2188	Transcriptional regulator
GEV26_RS04030	COG0577	efflux transmembrane transporter activity
GEV26_RS04065	COG2200	EAL domain
GEV26_RS04120	COG1414	Transcriptional regulator
GEV26_RS04125	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
GEV26_RS04135	COG0183	Belongs to the thiolase family
GEV26_RS04155	COG1846	Transcriptional regulator
GEV26_RS04160	COG2409	Drug exporters of the RND superfamily
GEV26_RS04175	COG0601	transmembrane transport
GEV26_RS04180	COG0444	Belongs to the ABC transporter superfamily
GEV26_RS04205	COG4948	Mandelate Racemase Muconate Lactonizing
GEV26_RS04220	COG1136	(ABC) transporter
GEV26_RS04220	COG0577	efflux transmembrane transporter activity
GEV26_RS04230	COG2197	response regulator
GEV26_RS04240	COG1522	sequence-specific DNA binding
GEV26_RS04255	COG1215	transferase activity, transferring glycosyl groups
GEV26_RS04265	COG5002	protein histidine kinase activity
GEV26_RS04270	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV26_RS04275	COG1902	pentaerythritol trinitrate reductase activity
GEV26_RS04310	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
GEV26_RS04330	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV26_RS04345	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GEV26_RS04350	COG1309	transcriptional regulator
GEV26_RS04355	COG2814	Major facilitator Superfamily
GEV26_RS04360	COG0515	serine threonine protein kinase
GEV26_RS04360	COG2815	serine threonine protein kinase
GEV26_RS04370	COG0384	phenazine biosynthesis protein PhzF
GEV26_RS04380	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GEV26_RS04400	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GEV26_RS04410	COG1695	Transcriptional regulator
GEV26_RS04415	COG0516	GMP reductase activity
GEV26_RS04415	COG0517	IMP dehydrogenase activity
GEV26_RS04420	COG0483	inositol monophosphate 1-phosphatase activity
GEV26_RS04430	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
GEV26_RS04440	COG2135	peptidase activity
GEV26_RS04445	COG1595	DNA-templated transcription, initiation
GEV26_RS04480	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GEV26_RS04495	COG0673	inositol 2-dehydrogenase activity
GEV26_RS04500	COG1879	ABC-type sugar transport system periplasmic component
GEV26_RS04505	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS04510	COG1129	ABC transporter
GEV26_RS04515	COG1940	carbohydrate kinase activity
GEV26_RS04520	COG2884	Cell division ATP-binding protein ftsE
GEV26_RS04525	COG2177	Part of the ABC transporter FtsEX involved in
GEV26_RS04540	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GEV26_RS04550	COG0477	Major facilitator Superfamily
GEV26_RS04560	COG2154	pterin-4-alpha-carbinolamine dehydratase
GEV26_RS04570	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GEV26_RS04575	COG1201	RNA secondary structure unwinding
GEV26_RS04590	COG1470	cell adhesion involved in biofilm formation
GEV26_RS04595	COG1309	transcriptional regulator
GEV26_RS04610	COG1678	Uncharacterized ACR, COG1678
GEV26_RS04650	COG4552	Acetyltransferase involved in intracellular survival and related
GEV26_RS04655	COG1335	isochorismatase
GEV26_RS04665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
GEV26_RS04695	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GEV26_RS04700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GEV26_RS04710	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
GEV26_RS04715	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GEV26_RS04725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GEV26_RS04730	COG3135	benzoate transporter
GEV26_RS04755	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV26_RS04760	COG0798	PFAM Bile acid sodium symporter
GEV26_RS04765	COG0640	Transcriptional regulator
GEV26_RS04785	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GEV26_RS04790	COG4129	membrane
GEV26_RS04795	COG1785	Belongs to the alkaline phosphatase family
GEV26_RS04805	COG2301	Belongs to the HpcH HpaI aldolase family
GEV26_RS04810	COG2301	Belongs to the HpcH HpaI aldolase family
GEV26_RS04860	COG0406	alpha-ribazole phosphatase activity
GEV26_RS04865	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GEV26_RS04875	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GEV26_RS04900	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEV26_RS04905	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GEV26_RS04920	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GEV26_RS04935	COG3706	GGDEF domain
GEV26_RS04935	COG4251	negative regulation of phosphorylation
GEV26_RS04935	COG5001	Diguanylate cyclase
GEV26_RS04935	COG2203	Gaf domain
GEV26_RS04950	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GEV26_RS04975	COG2353	YceI-like domain
GEV26_RS04985	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS04990	COG0183	Belongs to the thiolase family
GEV26_RS04995	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS05000	COG2030	dehydratase
GEV26_RS05005	COG0736	holo-[acyl-carrier-protein] synthase activity
GEV26_RS05015	COG1472	Belongs to the glycosyl hydrolase 3 family
GEV26_RS05035	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV26_RS05040	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GEV26_RS05050	COG2346	COG2346, Truncated hemoglobins
GEV26_RS05055	COG0668	transmembrane transport
GEV26_RS05070	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS05080	COG0463	Glycosyl transferase, family 2
GEV26_RS05095	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GEV26_RS05100	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GEV26_RS05145	COG0544	peptidyl-prolyl cis-trans isomerase activity
GEV26_RS05165	COG2188	Transcriptional regulator
GEV26_RS05175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV26_RS05185	COG3718	enzyme involved in inositol metabolism
GEV26_RS05190	COG3962	Belongs to the TPP enzyme family
GEV26_RS05220	COG0673	inositol 2-dehydrogenase activity
GEV26_RS05230	COG0673	inositol 2-dehydrogenase activity
GEV26_RS05235	COG3622	Belongs to the hyi family
GEV26_RS05250	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS05255	COG0740	serine-type endopeptidase activity
GEV26_RS05260	COG0740	serine-type endopeptidase activity
GEV26_RS05265	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GEV26_RS05270	COG3268	Saccharopine dehydrogenase
GEV26_RS05275	COG1271	oxidase subunit
GEV26_RS05285	COG0525	valine-tRNA ligase activity
GEV26_RS05290	COG2409	Drug exporters of the RND superfamily
GEV26_RS05295	COG0285	dihydrofolate synthase activity
GEV26_RS05335	COG0366	Alpha amylase catalytic
GEV26_RS05340	COG0105	UTP biosynthetic process
GEV26_RS05360	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
GEV26_RS05370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV26_RS05395	COG2807	transmembrane transport
GEV26_RS05405	COG1530	ribonuclease E activity
GEV26_RS05410	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GEV26_RS05415	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GEV26_RS05420	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GEV26_RS05425	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GEV26_RS05430	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GEV26_RS05435	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GEV26_RS05440	COG0799	negative regulation of ribosome biogenesis
GEV26_RS05445	COG0406	alpha-ribazole phosphatase activity
GEV26_RS05485	COG2814	Major facilitator Superfamily
GEV26_RS05490	COG3590	peptidase
GEV26_RS05530	COG1216	Glycosyl transferase, family 2
GEV26_RS05540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GEV26_RS05545	COG0569	domain protein
GEV26_RS05570	COG0495	leucyl-tRNA aminoacylation
GEV26_RS05575	COG1307	EDD domain protein, DegV family
GEV26_RS05580	COG1596	polysaccharide export
GEV26_RS05580	COG1555	photosystem II stabilization
GEV26_RS05590	COG0420	3'-5' exonuclease activity
GEV26_RS05595	COG0419	ATPase involved in DNA repair
GEV26_RS05610	COG0268	Binds directly to 16S ribosomal RNA
GEV26_RS05615	COG0481	GTPase activity
GEV26_RS05625	COG1022	Amp-dependent synthetase and ligase
GEV26_RS05645	COG1420	regulation of RNA biosynthetic process
GEV26_RS05650	COG0484	heat shock protein binding
GEV26_RS05655	COG0537	adenosine 5'-monophosphoramidase activity
GEV26_RS05665	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GEV26_RS05680	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GEV26_RS05690	COG1254	Belongs to the acylphosphatase family
GEV26_RS05715	COG0714	Associated with various cellular activities
GEV26_RS05730	COG0435	Glutathione S-transferase
GEV26_RS05740	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV26_RS05755	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS05775	COG1381	Involved in DNA repair and RecF pathway recombination
GEV26_RS05780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEV26_RS05815	COG0179	Fumarylacetoacetate (FAA) hydrolase
GEV26_RS05820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GEV26_RS05840	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS05855	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GEV26_RS05860	COG2301	Belongs to the HpcH HpaI aldolase family
GEV26_RS05865	COG1414	Transcriptional regulator
GEV26_RS05870	COG0683	leucine binding
GEV26_RS05930	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GEV26_RS05945	COG1414	Transcriptional regulator
GEV26_RS05950	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GEV26_RS05955	COG0066	3-isopropylmalate dehydratase activity
GEV26_RS05970	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GEV26_RS05975	COG0626	cystathionine gamma-synthase activity
GEV26_RS05980	COG1181	Belongs to the D-alanine--D-alanine ligase family
GEV26_RS06000	COG0154	amidase activity
GEV26_RS06005	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GEV26_RS06010	COG1461	Dihydroxyacetone kinase
GEV26_RS06020	COG0742	ribosomal rna small subunit methyltransferase
GEV26_RS06025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GEV26_RS06030	COG1595	DNA-templated transcription, initiation
GEV26_RS06040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GEV26_RS06050	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GEV26_RS06055	COG0571	ribonuclease III activity
GEV26_RS06060	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
GEV26_RS06070	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GEV26_RS06080	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GEV26_RS06095	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV26_RS06125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GEV26_RS06140	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
GEV26_RS06180	COG0028	Belongs to the TPP enzyme family
GEV26_RS06195	COG2890	protein-(glutamine-N5) methyltransferase activity
GEV26_RS06205	COG0514	ATP-dependent DNA helicase (RecQ)
GEV26_RS06210	COG0667	Aldo Keto reductase
GEV26_RS06215	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GEV26_RS06230	COG3022	response to hydroperoxide
GEV26_RS06240	COG2119	membrane
GEV26_RS06275	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GEV26_RS06280	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GEV26_RS06280	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GEV26_RS06290	COG4941	Belongs to the sigma-70 factor family
GEV26_RS06300	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
GEV26_RS06315	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV26_RS06385	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GEV26_RS06400	COG2755	lipolytic protein G-D-S-L family
GEV26_RS06415	COG0531	amino acid
GEV26_RS06425	COG1937	Protein conserved in bacteria
GEV26_RS06430	COG1309	transcriptional regulator
GEV26_RS06435	COG0300	oxidoreductase activity
GEV26_RS06460	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GEV26_RS06470	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS06475	COG1335	isochorismatase
GEV26_RS06495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS06500	COG2409	Drug exporters of the RND superfamily
GEV26_RS06505	COG4585	Histidine kinase
GEV26_RS06510	COG2197	response regulator
GEV26_RS06515	COG1733	regulation of RNA biosynthetic process
GEV26_RS06535	COG0582	viral genome integration into host DNA
GEV26_RS06555	COG0174	glutamine synthetase
GEV26_RS06575	COG4585	Histidine kinase
GEV26_RS06580	COG2197	response regulator
GEV26_RS06585	COG4152	abc transporter atp-binding protein
GEV26_RS06595	COG0321	lipoyl(octanoyl) transferase activity
GEV26_RS06615	COG0508	dehydrogenase complex catalyzes the overall conversion of
GEV26_RS06620	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GEV26_RS06635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
GEV26_RS06640	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GEV26_RS06660	COG0501	Belongs to the peptidase M48B family
GEV26_RS06685	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV26_RS06690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GEV26_RS06695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GEV26_RS06705	COG1376	ErfK ybiS ycfS ynhG family protein
GEV26_RS06710	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
GEV26_RS06715	COG0723	plastoquinol--plastocyanin reductase activity
GEV26_RS06720	COG2010	Cytochrome c
GEV26_RS06725	COG1845	cytochrome c oxidase, subunit III
GEV26_RS06735	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GEV26_RS06755	COG3883	PFAM NLP P60 protein
GEV26_RS06755	COG0791	NLP P60 protein
GEV26_RS06765	COG1022	Amp-dependent synthetase and ligase
GEV26_RS06780	COG1940	carbohydrate kinase activity
GEV26_RS06785	COG1940	carbohydrate kinase activity
GEV26_RS06805	COG0205	6-phosphofructokinase activity
GEV26_RS06815	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
GEV26_RS06820	COG0515	serine threonine protein kinase
GEV26_RS06820	COG2815	serine threonine protein kinase
GEV26_RS06825	COG0142	geranyltranstransferase activity
GEV26_RS06835	COG1231	oxidoreductase activity
GEV26_RS06840	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GEV26_RS06850	COG2001	Belongs to the MraZ family
GEV26_RS06855	COG0275	rRNA processing
GEV26_RS06865	COG0768	penicillin binding
GEV26_RS06870	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GEV26_RS06875	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GEV26_RS06880	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEV26_RS06885	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GEV26_RS06895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GEV26_RS06900	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GEV26_RS06905	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
GEV26_RS06915	COG1496	oxidoreductase activity
GEV26_RS06920	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GEV26_RS06925	COG1799	cell septum assembly
GEV26_RS06940	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GEV26_RS06945	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
GEV26_RS06950	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GEV26_RS06995	COG0587	DNA-directed DNA polymerase activity
GEV26_RS07005	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GEV26_RS07010	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GEV26_RS07015	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GEV26_RS07020	COG0131	Imidazoleglycerol-phosphate dehydratase
GEV26_RS07025	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GEV26_RS07030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GEV26_RS07040	COG0107	imidazoleglycerol-phosphate synthase activity
GEV26_RS07045	COG1132	(ABC) transporter
GEV26_RS07050	COG1132	(ABC) transporter
GEV26_RS07055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GEV26_RS07070	COG1714	RDD family
GEV26_RS07080	COG0134	indole-3-glycerol-phosphate synthase activity
GEV26_RS07085	COG0133	tryptophan synthase activity
GEV26_RS07090	COG0159	tryptophan synthase activity
GEV26_RS07095	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GEV26_RS07115	COG0069	glutamate synthase activity
GEV26_RS07115	COG0070	glutamate synthase
GEV26_RS07115	COG0067	glutamate synthase
GEV26_RS07125	COG0469	pyruvate kinase activity
GEV26_RS07195	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS07215	COG0438	transferase activity, transferring glycosyl groups
GEV26_RS07225	COG4981	capsule polysaccharide biosynthetic process
GEV26_RS07245	COG1362	aminopeptidase activity
GEV26_RS07250	COG0539	negative regulation of cytoplasmic translation
GEV26_RS07265	COG0237	dephospho-CoA kinase activity
GEV26_RS07270	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GEV26_RS07280	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GEV26_RS07295	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GEV26_RS07315	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV26_RS07315	COG2755	lipolytic protein G-D-S-L family
GEV26_RS07325	COG0477	Major facilitator Superfamily
GEV26_RS07335	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GEV26_RS07355	COG1435	thymidine kinase activity
GEV26_RS07365	COG2860	membrane
GEV26_RS07370	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS07380	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GEV26_RS07405	COG0756	dUTP diphosphatase activity
GEV26_RS07430	COG0569	domain protein
GEV26_RS07435	COG0531	amino acid
GEV26_RS07440	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GEV26_RS07450	COG0477	Major facilitator Superfamily
GEV26_RS07465	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GEV26_RS07470	COG4213	ABC transporter substrate-binding protein
GEV26_RS07480	COG4214	carbohydrate transport
GEV26_RS07500	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GEV26_RS07525	COG2226	methyltransferase
GEV26_RS07545	COG1073	alpha beta
GEV26_RS07560	COG4941	Belongs to the sigma-70 factor family
GEV26_RS07570	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS07585	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GEV26_RS07610	COG1755	Isoprenylcysteine carboxyl methyltransferase
GEV26_RS07615	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GEV26_RS07660	COG4585	Histidine kinase
GEV26_RS07665	COG2197	response regulator
GEV26_RS07670	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
GEV26_RS07690	COG0583	DNA-binding transcription factor activity
GEV26_RS07725	COG1940	carbohydrate kinase activity
GEV26_RS07735	COG1070	Carbohydrate kinase
GEV26_RS07750	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GEV26_RS07760	COG1946	Acyl-CoA thioesterase
GEV26_RS07765	COG2030	dehydratase
GEV26_RS07785	COG0556	nucleotide-excision repair
GEV26_RS07805	COG0531	amino acid
GEV26_RS07810	COG2124	cytochrome p450
GEV26_RS07845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GEV26_RS07850	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GEV26_RS07855	COG2354	Protein conserved in bacteria
GEV26_RS07860	COG0322	excinuclease ABC activity
GEV26_RS07865	COG1660	Displays ATPase and GTPase activities
GEV26_RS07875	COG1481	regulation of sporulation
GEV26_RS07880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GEV26_RS07885	COG0126	phosphoglycerate kinase activity
GEV26_RS07890	COG0149	triose-phosphate isomerase activity
GEV26_RS07895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GEV26_RS07905	COG0363	glucosamine-6-phosphate deaminase activity
GEV26_RS07920	COG0166	Belongs to the GPI family
GEV26_RS07925	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GEV26_RS07935	COG0109	protoheme IX farnesyltransferase activity
GEV26_RS08005	COG0483	inositol monophosphate 1-phosphatase activity
GEV26_RS08010	COG1612	heme a metabolic process
GEV26_RS08025	COG1793	dna ligase
GEV26_RS08030	COG2357	RelA SpoT domain protein
GEV26_RS08070	COG0396	ATPase activity
GEV26_RS08075	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GEV26_RS08085	COG2151	metal-sulfur cluster biosynthetic enzyme
GEV26_RS08090	COG0488	(ABC) transporter
GEV26_RS08100	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GEV26_RS08115	COG3360	Dodecin
GEV26_RS08125	COG0640	Transcriptional regulator
GEV26_RS08130	COG0560	Phosphoserine phosphatase
GEV26_RS08130	COG3830	Belongs to the UPF0237 family
GEV26_RS08135	COG1119	ATPase activity
GEV26_RS08155	COG1881	PFAM PEBP family protein
GEV26_RS08170	COG0242	peptide deformylase activity
GEV26_RS08175	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS08180	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS08200	COG0545	Peptidyl-prolyl cis-trans isomerase
GEV26_RS08205	COG1643	Atp-dependent helicase
GEV26_RS08220	COG2733	membrane
GEV26_RS08240	COG1131	(ABC) transporter
GEV26_RS08250	COG0515	serine threonine protein kinase
GEV26_RS08255	COG2267	carboxylic ester hydrolase activity
GEV26_RS08270	COG2066	Belongs to the glutaminase family
GEV26_RS08315	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEV26_RS08325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GEV26_RS08340	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GEV26_RS08370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV26_RS08400	COG0135	phosphoribosylanthranilate isomerase activity
GEV26_RS08420	COG0076	glutamate decarboxylase activity
GEV26_RS08430	COG0531	amino acid
GEV26_RS08445	COG0830	nickel cation binding
GEV26_RS08465	COG0549	Belongs to the carbamate kinase family
GEV26_RS08470	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GEV26_RS08475	COG2235	arginine
GEV26_RS08480	COG1288	antiporter activity
GEV26_RS08520	COG1239	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
GEV26_RS08545	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GEV26_RS08595	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GEV26_RS08605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV26_RS08615	COG0667	Aldo Keto reductase
GEV26_RS08620	COG1968	undecaprenyl-diphosphatase activity
GEV26_RS08630	COG0598	Magnesium transport protein CorA
GEV26_RS08635	COG0215	cysteine-tRNA ligase activity
GEV26_RS08655	COG0646	methionine synthase
GEV26_RS08655	COG1410	methionine synthase
GEV26_RS08665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GEV26_RS08670	COG1994	Peptidase M50
GEV26_RS08670	COG0517	IMP dehydrogenase activity
GEV26_RS08680	COG1222	aaa ATPase
GEV26_RS08700	COG4122	O-methyltransferase activity
GEV26_RS08705	COG1120	ATPase activity
GEV26_RS08710	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV26_RS08715	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV26_RS08730	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GEV26_RS08735	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GEV26_RS08745	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
GEV26_RS08765	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GEV26_RS08770	COG0805	protein transport
GEV26_RS08780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GEV26_RS08795	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GEV26_RS08800	COG0463	Glycosyl transferase, family 2
GEV26_RS08820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GEV26_RS08825	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GEV26_RS08870	COG2936	dipeptidyl-peptidase activity
GEV26_RS08885	COG2207	Transcriptional regulator
GEV26_RS08905	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GEV26_RS08905	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GEV26_RS08925	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV26_RS08950	COG0009	L-threonylcarbamoyladenylate synthase
GEV26_RS08955	COG0175	sulfate reduction
GEV26_RS08970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
GEV26_RS08970	COG1648	precorrin-2 dehydrogenase activity
GEV26_RS09005	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09010	COG1595	DNA-templated transcription, initiation
GEV26_RS09025	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV26_RS09025	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GEV26_RS09045	COG1716	ATPase activity
GEV26_RS09050	COG0509	glycine decarboxylation via glycine cleavage system
GEV26_RS09075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GEV26_RS09100	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GEV26_RS09105	COG0488	(ABC) transporter
GEV26_RS09135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS09140	COG2501	S4 domain
GEV26_RS09150	COG0494	nUDIX hydrolase
GEV26_RS09185	COG0590	tRNA wobble adenosine to inosine editing
GEV26_RS09200	COG0121	glutamine amidotransferase
GEV26_RS09210	COG1024	Enoyl-CoA hydratase
GEV26_RS09215	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS09235	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09245	COG1946	Acyl-CoA thioesterase
GEV26_RS09270	COG1024	Enoyl-CoA hydratase
GEV26_RS09275	COG1024	Enoyl-CoA hydratase
GEV26_RS09295	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS09305	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09310	COG0747	negative chemotaxis
GEV26_RS09320	COG0183	Belongs to the thiolase family
GEV26_RS09335	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09355	COG0667	Aldo Keto reductase
GEV26_RS09365	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS09370	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
GEV26_RS09370	COG0778	Nitroreductase
GEV26_RS09385	COG1063	alcohol dehydrogenase
GEV26_RS09390	COG1024	Enoyl-CoA hydratase
GEV26_RS09400	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09415	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09425	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09435	COG1335	isochorismatase
GEV26_RS09450	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09480	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GEV26_RS09485	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV26_RS09520	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09525	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09530	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09535	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09540	COG1024	Enoyl-CoA hydratase
GEV26_RS09555	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS09565	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS09570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GEV26_RS09585	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09595	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09600	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09605	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS09615	COG0747	negative chemotaxis
GEV26_RS09620	COG0183	Belongs to the thiolase family
GEV26_RS09625	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09630	COG1024	Enoyl-CoA hydratase
GEV26_RS09640	COG1024	Enoyl-CoA hydratase
GEV26_RS09645	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS09650	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS09655	COG0183	Belongs to the thiolase family
GEV26_RS09660	COG1946	Acyl-CoA thioesterase
GEV26_RS09685	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS09690	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09695	COG2084	Dehydrogenase
GEV26_RS09710	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS09715	COG0477	Major facilitator Superfamily
GEV26_RS09735	COG1946	Acyl-CoA thioesterase
GEV26_RS09740	COG2188	Transcriptional regulator
GEV26_RS09745	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS09770	COG1160	GTP binding
GEV26_RS09775	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GEV26_RS09790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GEV26_RS09815	COG0494	nUDIX hydrolase
GEV26_RS09820	COG0504	CTP synthase activity
GEV26_RS09835	COG0497	DNA recombination
GEV26_RS09840	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GEV26_RS09855	COG0647	UMP catabolic process
GEV26_RS09885	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GEV26_RS09890	COG0589	response to stress
GEV26_RS09900	COG0589	response to stress
GEV26_RS09920	COG3290	protein histidine kinase activity
GEV26_RS09925	COG4565	transcriptional regulatory protein
GEV26_RS09930	COG2094	Belongs to the DNA glycosylase MPG family
GEV26_RS09935	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GEV26_RS09940	COG0165	Argininosuccinate lyase
GEV26_RS09945	COG1438	arginine binding
GEV26_RS09950	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GEV26_RS09955	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GEV26_RS09960	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GEV26_RS09965	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
GEV26_RS09970	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GEV26_RS09975	COG0137	argininosuccinate synthase activity
GEV26_RS09985	COG0072	phenylalanine-tRNA ligase activity
GEV26_RS09985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEV26_RS09990	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GEV26_RS09995	COG5002	protein histidine kinase activity
GEV26_RS10000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GEV26_RS10005	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GEV26_RS10010	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GEV26_RS10015	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GEV26_RS10045	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GEV26_RS10050	COG0140	phosphoribosyl-ATP diphosphatase activity
GEV26_RS10055	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GEV26_RS10060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV26_RS10060	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GEV26_RS10075	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GEV26_RS10090	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GEV26_RS10100	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GEV26_RS10110	COG1758	RNA polymerase activity
GEV26_RS10115	COG0194	GDP metabolic process
GEV26_RS10130	COG0284	orotidine-5'-phosphate decarboxylase activity
GEV26_RS10135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GEV26_RS10140	COG0505	Belongs to the CarA family
GEV26_RS10145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GEV26_RS10150	COG0540	Belongs to the ATCase OTCase family
GEV26_RS10155	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GEV26_RS10165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GEV26_RS10170	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GEV26_RS10175	COG0006	proline dipeptidase activity
GEV26_RS10180	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GEV26_RS10185	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GEV26_RS10190	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GEV26_RS10200	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GEV26_RS10210	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GEV26_RS10215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GEV26_RS10235	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GEV26_RS10240	COG0124	histidyl-tRNA synthetase
GEV26_RS10250	COG1196	nuclear chromosome segregation
GEV26_RS10260	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GEV26_RS10265	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GEV26_RS10270	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GEV26_RS10275	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GEV26_RS10280	COG1862	Preprotein translocase
GEV26_RS10285	COG2255	four-way junction helicase activity
GEV26_RS10290	COG0632	four-way junction helicase activity
GEV26_RS10295	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GEV26_RS10300	COG0217	transcriptional regulatory protein
GEV26_RS10305	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
GEV26_RS10310	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
GEV26_RS10325	COG0659	secondary active sulfate transmembrane transporter activity
GEV26_RS10330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GEV26_RS10345	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GEV26_RS10350	COG2197	response regulator
GEV26_RS10390	COG1131	(ABC) transporter
GEV26_RS10415	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GEV26_RS10445	COG0754	glutathionylspermidine amidase activity
GEV26_RS10470	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS10490	COG3180	Ammonia monooxygenase
GEV26_RS10495	COG2326	polyphosphate kinase activity
GEV26_RS10510	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEV26_RS10515	COG3253	May function as heme-dependent peroxidase
GEV26_RS10525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GEV26_RS10550	COG0667	Aldo Keto reductase
GEV26_RS10560	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GEV26_RS10630	COG2249	NAD(P)H dehydrogenase (quinone) activity
GEV26_RS10650	COG0343	queuine tRNA-ribosyltransferase activity
GEV26_RS10660	COG0644	oxidoreductase
GEV26_RS10710	COG1278	Cold shock
GEV26_RS10720	COG2133	pyrroloquinoline quinone binding
GEV26_RS10730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GEV26_RS10770	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV26_RS10810	COG0515	serine threonine protein kinase
GEV26_RS10810	COG2815	serine threonine protein kinase
GEV26_RS10830	COG3321	synthase
GEV26_RS10830	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS10830	COG0604	alcohol dehydrogenase
GEV26_RS10840	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV26_RS10845	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GEV26_RS10850	COG1074	ATP-dependent DNA helicase activity
GEV26_RS10855	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
GEV26_RS10935	COG1396	sequence-specific DNA binding
GEV26_RS10950	COG1074	ATP-dependent DNA helicase activity
GEV26_RS11015	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV26_RS11025	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GEV26_RS11030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GEV26_RS11035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GEV26_RS11040	COG5001	Diguanylate cyclase
GEV26_RS11055	COG0783	Belongs to the Dps family
GEV26_RS11065	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GEV26_RS11065	COG0519	Catalyzes the synthesis of GMP from XMP
GEV26_RS11075	COG1295	ribonuclease BN
GEV26_RS11085	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GEV26_RS11110	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GEV26_RS11115	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GEV26_RS11120	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GEV26_RS11140	COG1309	transcriptional regulator
GEV26_RS11145	COG2409	Drug exporters of the RND superfamily
GEV26_RS11160	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS11165	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GEV26_RS11205	COG1126	abc transporter atp-binding protein
GEV26_RS11210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV26_RS11215	COG0765	amino acid transport
GEV26_RS11220	COG0765	amino acid transport
GEV26_RS11250	COG2137	regulation of response to DNA damage stimulus
GEV26_RS11255	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GEV26_RS11275	COG0395	ABC-type sugar transport system, permease component
GEV26_RS11280	COG1175	transmembrane transport
GEV26_RS11290	COG3842	ATPase activity
GEV26_RS11305	COG1058	Belongs to the CinA family
GEV26_RS11305	COG1546	Belongs to the CinA family
GEV26_RS11320	COG1674	ftsk spoiiie
GEV26_RS11330	COG0303	'Molybdopterin
GEV26_RS11345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GEV26_RS11350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GEV26_RS11380	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GEV26_RS11405	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GEV26_RS11420	COG1185	polyribonucleotide nucleotidyltransferase activity
GEV26_RS11430	COG2755	lipolytic protein G-D-S-L family
GEV26_RS11445	COG5002	protein histidine kinase activity
GEV26_RS11450	COG0745	RESPONSE REGULATOR receiver
GEV26_RS11465	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GEV26_RS11470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GEV26_RS11475	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GEV26_RS11495	COG0779	Required for maturation of 30S ribosomal subunits
GEV26_RS11510	COG0442	prolyl-tRNA aminoacylation
GEV26_RS11530	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
GEV26_RS11535	COG0750	zinc metalloprotease
GEV26_RS11550	COG1131	(ABC) transporter
GEV26_RS11555	COG4585	Histidine kinase
GEV26_RS11560	COG2197	response regulator
GEV26_RS11590	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
GEV26_RS11595	COG1177	transmembrane transport
GEV26_RS11600	COG1176	ABC-type spermidine putrescine transport system, permease component I
GEV26_RS11605	COG3842	ATPase activity
GEV26_RS11635	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GEV26_RS11650	COG2308	Evidence 4 Homologs of previously reported genes of
GEV26_RS11650	COG2307	Protein conserved in bacteria
GEV26_RS11665	COG0233	cytoplasmic translational termination
GEV26_RS11670	COG0528	UMP kinase activity
GEV26_RS11675	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GEV26_RS11680	COG0052	Belongs to the universal ribosomal protein uS2 family
GEV26_RS11685	COG0741	lytic transglycosylase activity
GEV26_RS11685	COG0739	heme binding
GEV26_RS11685	COG1196	nuclear chromosome segregation
GEV26_RS11690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV26_RS11710	COG0792	nuclease activity
GEV26_RS11715	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
GEV26_RS11725	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GEV26_RS11730	COG0681	Belongs to the peptidase S26 family
GEV26_RS11735	COG0681	Belongs to the peptidase S26 family
GEV26_RS11740	COG0335	large ribosomal subunit rRNA binding
GEV26_RS11750	COG0336	Belongs to the RNA methyltransferase TrmD family
GEV26_RS11755	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GEV26_RS11760	COG1837	Belongs to the UPF0109 family
GEV26_RS11765	COG0228	four-way junction DNA binding
GEV26_RS11780	COG1393	Belongs to the ArsC family
GEV26_RS11800	COG3265	gluconokinase activity
GEV26_RS11815	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GEV26_RS11835	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GEV26_RS11840	COG4988	ABC transporter
GEV26_RS11845	COG1294	oxidase, subunit
GEV26_RS11850	COG1271	oxidase subunit
GEV26_RS11875	COG1196	nuclear chromosome segregation
GEV26_RS11895	COG2233	PERMEase
GEV26_RS11910	COG0423	glycine-tRNA ligase activity
GEV26_RS11915	COG3443	Belongs to the bacterial solute-binding protein 9 family
GEV26_RS11915	COG0803	Belongs to the bacterial solute-binding protein 9 family
GEV26_RS11920	COG1121	(ABC) transporter
GEV26_RS11925	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GEV26_RS11980	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GEV26_RS11990	COG1027	Aspartate ammonia-lyase
GEV26_RS11995	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GEV26_RS12000	COG0473	3-isopropylmalate dehydrogenase activity
GEV26_RS12025	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GEV26_RS12030	COG0440	acetolactate synthase activity
GEV26_RS12060	COG0129	dihydroxy-acid dehydratase activity
GEV26_RS12085	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GEV26_RS12095	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEV26_RS12100	COG0154	amidase activity
GEV26_RS12105	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
GEV26_RS12125	COG0564	pseudouridine synthase activity
GEV26_RS12130	COG3634	alkyl hydroperoxide reductase activity
GEV26_RS12135	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GEV26_RS12145	COG0482	sulfurtransferase activity
GEV26_RS12160	COG1104	cysteine desulfurase activity
GEV26_RS12170	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GEV26_RS12175	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GEV26_RS12185	COG1793	dna ligase
GEV26_RS12200	COG2197	response regulator
GEV26_RS12210	COG0587	DNA-directed DNA polymerase activity
GEV26_RS12230	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GEV26_RS12245	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GEV26_RS12250	COG2086	electron transfer activity
GEV26_RS12270	COG2226	methyltransferase
GEV26_RS12285	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
GEV26_RS12290	COG3281	Trehalose synthase
GEV26_RS12295	COG0366	Alpha amylase catalytic
GEV26_RS12300	COG0366	Alpha amylase catalytic
GEV26_RS12365	COG0442	prolyl-tRNA aminoacylation
GEV26_RS12370	COG0494	nUDIX hydrolase
GEV26_RS12395	COG0183	Belongs to the thiolase family
GEV26_RS12435	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
GEV26_RS12440	COG1528	Iron-storage protein
GEV26_RS12445	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV26_RS12445	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV26_RS12465	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GEV26_RS12470	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GEV26_RS12475	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GEV26_RS12480	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GEV26_RS12485	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEV26_RS12490	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GEV26_RS12495	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GEV26_RS12500	COG0356	it plays a direct role in the translocation of protons across the membrane
GEV26_RS12510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GEV26_RS12525	COG2890	protein-(glutamine-N5) methyltransferase activity
GEV26_RS12530	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GEV26_RS12535	COG0254	rRNA binding
GEV26_RS12540	COG2072	flavoprotein involved in K transport
GEV26_RS12545	COG0385	Bile acid
GEV26_RS12555	COG0386	Belongs to the glutathione peroxidase family
GEV26_RS12575	COG0460	homoserine dehydrogenase
GEV26_RS12595	COG0019	diaminopimelate decarboxylase activity
GEV26_RS12600	COG0018	arginyl-trna synthetase
GEV26_RS12605	COG0784	Response regulator, receiver
GEV26_RS12605	COG0643	Histidine kinase
GEV26_RS12605	COG2198	Histidine kinase
GEV26_RS12630	COG3979	chitinase
GEV26_RS12640	COG0567	Dehydrogenase, E1 component
GEV26_RS12640	COG0508	dehydrogenase complex catalyzes the overall conversion of
GEV26_RS12655	COG0604	alcohol dehydrogenase
GEV26_RS12690	COG1132	(ABC) transporter
GEV26_RS12740	COG4962	Type ii secretion system protein e
GEV26_RS12745	COG2318	DinB family
GEV26_RS12755	COG0745	RESPONSE REGULATOR receiver
GEV26_RS12760	COG2205	protein histidine kinase activity
GEV26_RS12765	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
GEV26_RS12775	COG1842	Phage shock protein A
GEV26_RS12825	COG0653	protein targeting
GEV26_RS12830	COG3214	Protein conserved in bacteria
GEV26_RS12835	COG2197	response regulator
GEV26_RS12840	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GEV26_RS12845	COG1040	competence protein
GEV26_RS12850	COG0823	Involved in the tonB-independent uptake of proteins
GEV26_RS12855	COG5002	protein histidine kinase activity
GEV26_RS12860	COG0745	RESPONSE REGULATOR receiver
GEV26_RS12865	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GEV26_RS12900	COG2835	tetraacyldisaccharide 4'-kinase activity
GEV26_RS12950	COG1134	teichoic acid transport
GEV26_RS12950	COG1388	LysM domain
GEV26_RS12955	COG1316	TRANSCRIPTIONal
GEV26_RS12965	COG1316	TRANSCRIPTIONal
GEV26_RS12975	COG2171	N-acyltransferase activity
GEV26_RS13005	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GEV26_RS13015	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV26_RS13035	COG0488	(ABC) transporter
GEV26_RS13040	COG0277	FAD linked oxidase domain protein
GEV26_RS13045	COG0385	Bile acid
GEV26_RS13065	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GEV26_RS13080	COG0328	RNA-DNA hybrid ribonuclease activity
GEV26_RS13125	COG2226	methyltransferase
GEV26_RS13165	COG0012	GTP binding
GEV26_RS13195	COG1322	Protein conserved in bacteria
GEV26_RS13210	COG0405	Gamma-glutamyltransferase
GEV26_RS13215	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
GEV26_RS13225	COG1570	exodeoxyribonuclease VII activity
GEV26_RS13230	COG1722	exodeoxyribonuclease VII activity
GEV26_RS13250	COG2808	Putative FMN-binding domain
GEV26_RS13285	COG0114	fumarate hydratase activity
GEV26_RS13300	COG0395	ABC-type sugar transport system, permease component
GEV26_RS13315	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
GEV26_RS13320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GEV26_RS13330	COG1331	Highly conserved protein containing a thioredoxin domain
GEV26_RS13355	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GEV26_RS13365	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GEV26_RS13370	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GEV26_RS13380	COG2315	Protein conserved in bacteria
GEV26_RS13390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GEV26_RS13395	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GEV26_RS13400	COG3663	DNA glycosylase
GEV26_RS13405	COG1733	regulation of RNA biosynthetic process
GEV26_RS13410	COG0702	epimerase
GEV26_RS13430	COG2755	lipolytic protein G-D-S-L family
GEV26_RS13440	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GEV26_RS13460	COG0667	Aldo Keto reductase
GEV26_RS13500	COG5012	cobalamin binding
GEV26_RS13510	COG5598	trimethylamine methyltransferase
GEV26_RS13520	COG1414	Transcriptional regulator
GEV26_RS13525	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS13535	COG4175	Glycine betaine
GEV26_RS13540	COG4176	ABC-type proline glycine betaine transport system permease component
GEV26_RS13555	COG2086	electron transfer activity
GEV26_RS13560	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GEV26_RS13565	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GEV26_RS13580	COG1070	Carbohydrate kinase
GEV26_RS13585	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS13585	COG3347	Dehydrogenase
GEV26_RS13595	COG3254	rhamnose metabolic process
GEV26_RS13610	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS13615	COG1129	ABC transporter
GEV26_RS13620	COG1609	Transcriptional regulator
GEV26_RS13635	COG1301	dicarboxylic acid transport
GEV26_RS13650	COG0148	phosphopyruvate hydratase activity
GEV26_RS13665	COG0531	amino acid
GEV26_RS13695	COG1316	TRANSCRIPTIONal
GEV26_RS13710	COG0673	inositol 2-dehydrogenase activity
GEV26_RS13740	COG0438	transferase activity, transferring glycosyl groups
GEV26_RS13780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
GEV26_RS13785	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GEV26_RS13790	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
GEV26_RS13830	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GEV26_RS13835	COG0193	aminoacyl-tRNA hydrolase activity
GEV26_RS13840	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GEV26_RS13845	COG5002	protein histidine kinase activity
GEV26_RS13890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GEV26_RS13900	COG4106	trans-aconitate 2-methyltransferase activity
GEV26_RS13910	COG1846	Transcriptional regulator
GEV26_RS13915	COG0488	(ABC) transporter
GEV26_RS13925	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
GEV26_RS13935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GEV26_RS13940	COG3583	domain protein
GEV26_RS13945	COG0084	hydrolase, TatD family'
GEV26_RS13950	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GEV26_RS13965	COG5001	Diguanylate cyclase
GEV26_RS13995	COG1773	rubredoxin
GEV26_RS14005	COG3239	Fatty acid desaturase
GEV26_RS14015	COG1595	DNA-templated transcription, initiation
GEV26_RS14025	COG0656	L-ascorbic acid biosynthetic process
GEV26_RS14050	COG0521	Mo-molybdopterin cofactor biosynthetic process
GEV26_RS14050	COG0315	cyclic pyranopterin monophosphate synthase activity
GEV26_RS14055	COG0315	cyclic pyranopterin monophosphate synthase activity
GEV26_RS14070	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GEV26_RS14100	COG1970	mechanosensitive ion channel activity
GEV26_RS14130	COG0598	Magnesium transport protein CorA
GEV26_RS14145	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
GEV26_RS14150	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
GEV26_RS14155	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
GEV26_RS14165	COG3158	transport of potassium into the cell
GEV26_RS14180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GEV26_RS14190	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GEV26_RS14215	COG0477	Major facilitator Superfamily
GEV26_RS14235	COG0259	pyridoxamine-phosphate oxidase activity
GEV26_RS14255	COG1305	Transglutaminase-like
GEV26_RS14280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GEV26_RS14290	COG2252	PERMEase
GEV26_RS14315	COG2814	Major facilitator Superfamily
GEV26_RS14325	COG1295	ribonuclease BN
GEV26_RS14335	COG1595	DNA-templated transcription, initiation
GEV26_RS14345	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS14350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GEV26_RS14360	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GEV26_RS14400	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS14410	COG1045	serine acetyltransferase
GEV26_RS14420	COG1131	(ABC) transporter
GEV26_RS14425	COG3483	tryptophan 2,3-dioxygenase activity
GEV26_RS14430	COG2814	Major facilitator Superfamily
GEV26_RS14440	COG2838	Isocitrate dehydrogenase
GEV26_RS14445	COG0039	L-malate dehydrogenase activity
GEV26_RS14455	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GEV26_RS14470	COG3655	Transcriptional regulator
GEV26_RS14475	COG0138	bifunctional purine biosynthesis protein purh
GEV26_RS14500	COG0045	succinate-CoA ligase (ADP-forming) activity
GEV26_RS14525	COG1725	Transcriptional regulator
GEV26_RS14535	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GEV26_RS14545	COG2197	response regulator
GEV26_RS14565	COG1983	PspC domain protein
GEV26_RS14570	COG0584	glycerophosphoryl diester phosphodiesterase
GEV26_RS14575	COG0405	Gamma-glutamyltransferase
GEV26_RS14580	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GEV26_RS14585	COG3387	PFAM Glycoside hydrolase 15-related
GEV26_RS14590	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
GEV26_RS14605	COG0519	Catalyzes the synthesis of GMP from XMP
GEV26_RS14605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GEV26_RS14620	COG2837	iron assimilation
GEV26_RS14640	COG0516	GMP reductase activity
GEV26_RS14665	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
GEV26_RS14670	COG0459	protein refolding
GEV26_RS14675	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GEV26_RS14690	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
GEV26_RS14695	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
GEV26_RS14705	COG1472	Belongs to the glycosyl hydrolase 3 family
GEV26_RS14710	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GEV26_RS14715	COG2318	DinB family
GEV26_RS14740	COG0456	acetyltransferase
GEV26_RS14740	COG1214	PFAM Peptidase M22, glycoprotease
GEV26_RS14745	COG0802	atpase or kinase
GEV26_RS14755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GEV26_RS14765	COG0736	holo-[acyl-carrier-protein] synthase activity
GEV26_RS14770	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GEV26_RS14775	COG1072	(Pantothenic acid kinase))
GEV26_RS14795	COG0515	serine threonine protein kinase
GEV26_RS14795	COG2815	serine threonine protein kinase
GEV26_RS14800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GEV26_RS14805	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GEV26_RS14810	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GEV26_RS14820	COG0101	tRNA pseudouridine synthase activity
GEV26_RS14850	COG0203	ribosomal protein L17
GEV26_RS14855	COG0202	RNA polymerase activity
GEV26_RS14860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GEV26_RS14865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GEV26_RS14870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GEV26_RS14875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GEV26_RS14880	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GEV26_RS14885	COG1522	sequence-specific DNA binding
GEV26_RS14890	COG1834	amidinotransferase
GEV26_RS14910	COG0563	adenylate kinase activity
GEV26_RS14920	COG0200	Binds to the 23S rRNA
GEV26_RS14925	COG1841	ribosomal large subunit assembly
GEV26_RS14930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GEV26_RS14935	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GEV26_RS14940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GEV26_RS14945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GEV26_RS14950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GEV26_RS14955	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GEV26_RS14960	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GEV26_RS14965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GEV26_RS14970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GEV26_RS14975	COG0255	Belongs to the universal ribosomal protein uL29 family
GEV26_RS14980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GEV26_RS14985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GEV26_RS14990	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GEV26_RS14995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GEV26_RS15000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GEV26_RS15005	COG0089	rRNA binding
GEV26_RS15010	COG0088	Forms part of the polypeptide exit tunnel
GEV26_RS15015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GEV26_RS15020	COG0051	transcription antitermination factor activity, RNA binding
GEV26_RS15030	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GEV26_RS15035	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GEV26_RS15040	COG0049	tRNA binding
GEV26_RS15045	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GEV26_RS15055	COG0247	lactate metabolic process
GEV26_RS15055	COG0277	FAD linked oxidase domain protein
GEV26_RS15065	COG1802	Transcriptional regulator
GEV26_RS15080	COG3594	Acyltransferase
GEV26_RS15090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GEV26_RS15095	COG0085	RNA polymerase activity
GEV26_RS15140	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GEV26_RS15145	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GEV26_RS15155	COG0222	ribosome binding
GEV26_RS15165	COG0081	regulation of translation
GEV26_RS15170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GEV26_RS15180	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GEV26_RS15190	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
GEV26_RS15205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GEV26_RS15210	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GEV26_RS15240	COG0167	dihydroorotate dehydrogenase activity
GEV26_RS15250	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GEV26_RS15290	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS15315	COG0346	lactoylglutathione lyase activity
GEV26_RS15340	COG4221	oxidoreductase activity
GEV26_RS15355	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GEV26_RS15385	COG3546	catalase activity
GEV26_RS15410	COG3485	protocatechuate 3,4-dioxygenase
GEV26_RS15420	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS15425	COG0402	S-adenosylhomocysteine deaminase activity
GEV26_RS15430	COG1414	Transcriptional regulator
GEV26_RS15445	COG1063	alcohol dehydrogenase
GEV26_RS15465	COG1320	monovalent cation:proton antiporter activity
GEV26_RS15480	COG0651	ATP synthesis coupled electron transport
GEV26_RS15485	COG1006	Multisubunit Na H antiporter MnhC subunit
GEV26_RS15490	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GEV26_RS15490	COG2111	Na H antiporter
GEV26_RS15505	COG3485	protocatechuate 3,4-dioxygenase
GEV26_RS15525	COG4177	L-phenylalanine transmembrane transporter activity
GEV26_RS15540	COG1137	ATPase activity
GEV26_RS15555	COG1666	GTP binding
GEV26_RS15560	COG1007	ATP synthesis coupled electron transport
GEV26_RS15575	COG0713	ATP synthesis coupled electron transport
GEV26_RS15580	COG0839	Belongs to the complex I subunit 6 family
GEV26_RS15585	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV26_RS15590	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GEV26_RS15600	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV26_RS15605	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV26_RS15610	COG4221	oxidoreductase activity
GEV26_RS15625	COG0142	geranyltranstransferase activity
GEV26_RS15630	COG1007	ATP synthesis coupled electron transport
GEV26_RS15640	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GEV26_RS15645	COG0713	ATP synthesis coupled electron transport
GEV26_RS15655	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV26_RS15660	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GEV26_RS15665	COG1034	ATP synthesis coupled electron transport
GEV26_RS15670	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
GEV26_RS15680	COG0649	NAD binding
GEV26_RS15685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV26_RS15690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GEV26_RS15700	COG2226	methyltransferase
GEV26_RS15705	COG1169	isochorismate synthase
GEV26_RS15715	COG2755	lipolytic protein G-D-S-L family
GEV26_RS15720	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
GEV26_RS15720	COG1672	PFAM Archaeal ATPase
GEV26_RS15725	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS15735	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GEV26_RS15740	COG4948	Mandelate Racemase Muconate Lactonizing
GEV26_RS15745	COG0702	epimerase
GEV26_RS15790	COG1131	(ABC) transporter
GEV26_RS15800	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GEV26_RS15810	COG0785	Cytochrome C biogenesis protein
GEV26_RS15820	COG0406	alpha-ribazole phosphatase activity
GEV26_RS15825	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GEV26_RS15835	COG0113	porphobilinogen synthase activity
GEV26_RS15845	COG0181	hydroxymethylbilane synthase activity
GEV26_RS15850	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GEV26_RS15855	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
GEV26_RS15875	COG1595	DNA-templated transcription, initiation
GEV26_RS15905	COG0123	including yeast histone deacetylase and acetoin utilization protein
GEV26_RS15910	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GEV26_RS15920	COG1280	lysine exporter protein (LysE YggA)
GEV26_RS15925	COG1082	Xylose isomerase domain protein TIM barrel
GEV26_RS15930	COG0248	Ppx GppA phosphatase
GEV26_RS15955	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
GEV26_RS15965	COG1194	a g-specific adenine glycosylase
GEV26_RS15985	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GEV26_RS15990	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GEV26_RS15995	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GEV26_RS16005	COG1216	Glycosyl transferase, family 2
GEV26_RS16020	COG0649	NAD binding
GEV26_RS16040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GEV26_RS16055	COG0302	gtp cyclohydrolase
GEV26_RS16070	COG0037	tRNA processing
GEV26_RS16080	COG2027	D-alanyl-D-alanine carboxypeptidase
GEV26_RS16085	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GEV26_RS16115	COG1674	ftsk spoiiie
GEV26_RS16140	COG1404	Belongs to the peptidase S8 family
GEV26_RS16190	COG0667	Aldo Keto reductase
GEV26_RS16195	COG0789	Transcriptional regulator
GEV26_RS16210	COG0477	Major facilitator Superfamily
GEV26_RS16215	COG0531	amino acid
GEV26_RS16225	COG2130	NADP-dependent
GEV26_RS16245	COG1764	response to oxidative stress
GEV26_RS16260	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
GEV26_RS16265	COG1024	Enoyl-CoA hydratase
GEV26_RS16270	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
GEV26_RS16280	COG1278	Cold shock
GEV26_RS16290	COG3845	ABC transporter
GEV26_RS16340	COG1846	Transcriptional regulator
GEV26_RS16350	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV26_RS16350	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GEV26_RS16350	COG1703	isobutyryl-CoA mutase activity
GEV26_RS16355	COG2160	L-arabinose isomerase activity
GEV26_RS16370	COG1609	Transcriptional regulator
GEV26_RS16375	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS16380	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS16390	COG1879	ABC-type sugar transport system periplasmic component
GEV26_RS16395	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GEV26_RS16395	COG2755	lipolytic protein G-D-S-L family
GEV26_RS16410	COG1024	Enoyl-CoA hydratase
GEV26_RS16415	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV26_RS16425	COG0542	response to heat
GEV26_RS16480	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS16495	COG1914	H( )-stimulated, divalent metal cation uptake system
GEV26_RS16510	COG0531	amino acid
GEV26_RS16525	COG2267	carboxylic ester hydrolase activity
GEV26_RS16550	COG2050	protein possibly involved in aromatic compounds catabolism
GEV26_RS16555	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GEV26_RS16560	COG2151	metal-sulfur cluster biosynthetic enzyme
GEV26_RS16565	COG3396	Phenylacetate-CoA oxygenase
GEV26_RS16570	COG3460	Phenylacetate-CoA oxygenase
GEV26_RS16575	COG3396	Phenylacetate-CoA oxygenase
GEV26_RS16580	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS16580	COG2030	dehydratase
GEV26_RS16640	COG0318	PFAM AMP-dependent synthetase and ligase
GEV26_RS16650	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GEV26_RS16670	COG0789	Transcriptional regulator
GEV26_RS16675	COG0484	heat shock protein binding
GEV26_RS16680	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GEV26_RS16685	COG0443	Heat shock 70 kDa protein
GEV26_RS16700	COG2409	Drug exporters of the RND superfamily
GEV26_RS16705	COG1309	transcriptional regulator
GEV26_RS16720	COG1054	Belongs to the UPF0176 family
GEV26_RS16745	COG3046	protein related to deoxyribodipyrimidine photolyase
GEV26_RS16750	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS16770	COG1122	ATPase activity
GEV26_RS16775	COG4721	ABC-type cobalt transport system, permease component
GEV26_RS16780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GEV26_RS16805	COG2271	Major facilitator Superfamily
GEV26_RS16815	COG2267	carboxylic ester hydrolase activity
GEV26_RS16820	COG2181	nitrate reductase activity
GEV26_RS16820	COG0247	lactate metabolic process
GEV26_RS16825	COG3012	SEC-C Motif Domain Protein
GEV26_RS16835	COG1131	(ABC) transporter
GEV26_RS16840	COG2942	2-epimerase
GEV26_RS16845	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GEV26_RS16855	COG2313	pseudouridylate synthase activity
GEV26_RS16860	COG0717	Belongs to the dCTP deaminase family
GEV26_RS16870	COG0454	-acetyltransferase
GEV26_RS16905	COG0745	RESPONSE REGULATOR receiver
GEV26_RS16915	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GEV26_RS16935	COG2199	diguanylate cyclase activity
GEV26_RS16945	COG1739	Uncharacterized protein family UPF0029
GEV26_RS16960	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS16980	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS16995	COG0508	dehydrogenase complex catalyzes the overall conversion of
GEV26_RS17000	COG0022	dehydrogenase e1 component
GEV26_RS17010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GEV26_RS17015	COG0697	spore germination
GEV26_RS17020	COG1950	PFAM Membrane protein of
GEV26_RS17025	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GEV26_RS17035	COG0745	RESPONSE REGULATOR receiver
GEV26_RS17040	COG2205	protein histidine kinase activity
GEV26_RS17045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GEV26_RS17050	COG0697	spore germination
GEV26_RS17065	COG1053	succinate dehydrogenase
GEV26_RS17070	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS17075	COG1028	Short-chain dehydrogenase reductase Sdr
GEV26_RS17080	COG1902	pentaerythritol trinitrate reductase activity
GEV26_RS17090	COG1012	belongs to the aldehyde dehydrogenase family
GEV26_RS17105	COG1129	ABC transporter
GEV26_RS17130	COG1335	isochorismatase
GEV26_RS17150	COG1794	racemase activity, acting on amino acids and derivatives
GEV26_RS17165	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GEV26_RS17195	COG1126	abc transporter atp-binding protein
GEV26_RS17200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV26_RS17220	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GEV26_RS17225	COG1960	acyl-CoA dehydrogenase activity
GEV26_RS17260	COG0657	acetylesterase activity
GEV26_RS17290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
GEV26_RS17325	COG0300	oxidoreductase activity
GEV26_RS17365	COG1024	Enoyl-CoA hydratase
GEV26_RS17390	COG0702	epimerase
GEV26_RS17400	COG0531	amino acid
GEV26_RS17405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GEV26_RS17420	COG0300	oxidoreductase activity
GEV26_RS17430	COG1120	ATPase activity
GEV26_RS17435	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV26_RS17440	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GEV26_RS17445	COG1024	Enoyl-CoA hydratase
GEV26_RS17445	COG1250	3-hydroxyacyl-CoA dehydrogenase
GEV26_RS17450	COG0183	Belongs to the thiolase family
GEV26_RS17465	COG1804	L-carnitine dehydratase bile acid-inducible protein F
GEV26_RS17470	COG0596	Alpha beta hydrolase
GEV26_RS17495	COG0765	amino acid transport
GEV26_RS17500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GEV26_RS17510	COG1695	Transcriptional regulator
GEV26_RS17525	COG1902	pentaerythritol trinitrate reductase activity
GEV26_RS17525	COG0446	pyridine nucleotide-disulphide oxidoreductase
GEV26_RS17545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GEV26_RS17560	COG1937	Protein conserved in bacteria
GEV26_RS17585	COG1132	(ABC) transporter
GEV26_RS17595	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GEV26_RS17600	COG0586	Pfam SNARE associated Golgi protein
GEV26_RS17610	COG0305	Participates in initiation and elongation during chromosome replication
GEV26_RS17625	COG0747	negative chemotaxis
GEV26_RS17630	COG0359	binds to the 23S rRNA
GEV26_RS17635	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GEV26_RS17645	COG0360	Binds together with S18 to 16S ribosomal RNA
GEV26_RS17665	COG1643	Atp-dependent helicase
GEV26_RS17670	COG0667	Aldo Keto reductase
GEV26_RS17680	COG1305	Transglutaminase-like
GEV26_RS17715	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GEV26_RS17725	COG1260	myo-inositol-1-phosphate synthase
GEV26_RS17755	COG1172	Belongs to the binding-protein-dependent transport system permease family
GEV26_RS17765	COG0617	tRNA 3'-terminal CCA addition
GEV26_RS17785	COG0492	ferredoxin-NADP+ reductase activity
GEV26_RS17790	COG3118	belongs to the thioredoxin family
GEV26_RS17800	COG1192	Involved in chromosome partitioning
GEV26_RS17805	COG0357	Ribosomal RNA small subunit methyltransferase G
GEV26_RS17815	COG0706	membrane insertase activity
GEV26_RS17820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GEV26_RS17825	COG0594	ribonuclease P activity