locus-tag	class	description
OPI30_RS00075	COG4644	lycopene metabolic process
OPI30_RS00085	COG1192	Involved in chromosome partitioning
OPI30_RS00090	COG3077	Addiction module antitoxin, RelB DinJ family
OPI30_RS00095	COG2026	Addiction module toxin, RelE StbE family
OPI30_RS00115	COG3328	transposase activity
OPI30_RS00125	COG3385	transposase activity
OPI30_RS00255	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPI30_RS00260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS00265	COG1309	transcriptional regulator
OPI30_RS00295	COG0561	phosphatase activity
OPI30_RS00300	COG2267	carboxylic ester hydrolase activity
OPI30_RS00305	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPI30_RS00310	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OPI30_RS00315	COG1758	RNA polymerase activity
OPI30_RS00325	COG0859	PFAM glycosyl transferase family 9
OPI30_RS00330	COG3642	lipopolysaccharide core region biosynthetic process
OPI30_RS00370	COG0589	response to stress
OPI30_RS00375	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OPI30_RS00380	COG3706	GGDEF domain
OPI30_RS00385	COG1528	Iron-storage protein
OPI30_RS00390	COG2081	HI0933 family
OPI30_RS00395	COG2223	nitrite transmembrane transporter activity
OPI30_RS00400	COG1280	lysine exporter protein (LysE YggA)
OPI30_RS00425	COG3275	phosphorelay sensor kinase activity
OPI30_RS00430	COG3279	Response regulator of the LytR AlgR family
OPI30_RS00435	COG2223	nitrite transmembrane transporter activity
OPI30_RS00445	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OPI30_RS00450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OPI30_RS00505	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OPI30_RS00510	COG2166	iron-sulfur cluster assembly
OPI30_RS00515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OPI30_RS00535	COG1063	alcohol dehydrogenase
OPI30_RS00550	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OPI30_RS00555	COG0438	transferase activity, transferring glycosyl groups
OPI30_RS00560	COG3307	-O-antigen
OPI30_RS00635	COG1580	Controls the rotational direction of flagella during chemotaxis
OPI30_RS00640	COG3161	chorismate lyase activity
OPI30_RS00645	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OPI30_RS00650	COG2937	Belongs to the GPAT DAPAT family
OPI30_RS00655	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OPI30_RS00670	COG0534	Mate efflux family protein
OPI30_RS00675	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OPI30_RS00680	COG2205	protein histidine kinase activity
OPI30_RS00685	COG0745	RESPONSE REGULATOR receiver
OPI30_RS00695	COG1045	serine acetyltransferase
OPI30_RS00705	COG3074	FtsZ-dependent cytokinesis
OPI30_RS00710	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
OPI30_RS00715	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OPI30_RS00715	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OPI30_RS00720	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OPI30_RS00760	COG1609	Transcriptional regulator
OPI30_RS00765	COG3250	beta-galactosidase activity
OPI30_RS00770	COG2731	YhcH YjgK YiaL family protein
OPI30_RS00775	COG0531	amino acid
OPI30_RS00780	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPI30_RS00785	COG0531	amino acid
OPI30_RS00790	COG0385	Bile acid
OPI30_RS00795	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OPI30_RS00820	COG0583	DNA-binding transcription factor activity
OPI30_RS00830	COG1079	Belongs to the binding-protein-dependent transport system permease family
OPI30_RS00835	COG4603	Belongs to the binding-protein-dependent transport system permease family
OPI30_RS00840	COG3845	ABC transporter
OPI30_RS00845	COG1744	ABC transporter substrate-binding protein PnrA-like
OPI30_RS00860	COG0210	DNA helicase
OPI30_RS00875	COG5433	transposase activity
OPI30_RS00925	COG0583	DNA-binding transcription factor activity
OPI30_RS00965	COG1280	lysine exporter protein (LysE YggA)
OPI30_RS00975	COG2962	Rard protein
OPI30_RS00985	COG1012	belongs to the aldehyde dehydrogenase family
OPI30_RS00990	COG1396	sequence-specific DNA binding
OPI30_RS00995	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OPI30_RS01005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OPI30_RS01005	COG0519	Catalyzes the synthesis of GMP from XMP
OPI30_RS01015	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPI30_RS01035	COG1322	Protein conserved in bacteria
OPI30_RS01040	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OPI30_RS01045	COG0569	domain protein
OPI30_RS01050	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OPI30_RS01050	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OPI30_RS01055	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OPI30_RS01060	COG0242	peptide deformylase activity
OPI30_RS01070	COG0758	DNA mediated transformation
OPI30_RS01075	COG2922	Belongs to the Smg family
OPI30_RS01080	COG0551	DNA topoisomerase type I activity
OPI30_RS01085	COG0009	L-threonylcarbamoyladenylate synthase
OPI30_RS01090	COG0408	coproporphyrinogen oxidase activity
OPI30_RS01095	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OPI30_RS01105	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OPI30_RS01115	COG3078	GTPase activator activity
OPI30_RS01125	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OPI30_RS01130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OPI30_RS01135	COG2204	response regulator
OPI30_RS01140	COG3852	Histidine kinase
OPI30_RS01150	COG0174	glutamine synthetase
OPI30_RS01155	COG1217	gtp-binding protein TYPA
OPI30_RS01160	COG1295	ribonuclease BN
OPI30_RS01165	COG1490	D-aminoacyl-tRNA deacylase activity
OPI30_RS01175	COG0456	acetyltransferase
OPI30_RS01185	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OPI30_RS01190	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPI30_RS01195	COG2610	gluconate transmembrane transporter activity
OPI30_RS01200	COG3265	gluconokinase activity
OPI30_RS01205	COG0129	dihydroxy-acid dehydratase activity
OPI30_RS01210	COG0800	Aldolase
OPI30_RS01225	COG1609	Transcriptional regulator
OPI30_RS01235	COG4942	peptidase
OPI30_RS01240	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OPI30_RS01245	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OPI30_RS01250	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OPI30_RS01255	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OPI30_RS01260	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OPI30_RS01260	COG0316	Belongs to the HesB IscA family
OPI30_RS01265	COG1040	competence protein
OPI30_RS01270	COG0596	Alpha beta hydrolase
OPI30_RS01285	COG2183	response to ionizing radiation
OPI30_RS01290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OPI30_RS01300	COG2205	protein histidine kinase activity
OPI30_RS01310	COG0051	transcription antitermination factor activity, RNA binding
OPI30_RS01315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OPI30_RS01320	COG0088	Forms part of the polypeptide exit tunnel
OPI30_RS01325	COG0089	rRNA binding
OPI30_RS01330	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OPI30_RS01335	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OPI30_RS01340	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OPI30_RS01345	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OPI30_RS01350	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OPI30_RS01355	COG0255	Belongs to the universal ribosomal protein uL29 family
OPI30_RS01360	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OPI30_RS01365	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OPI30_RS01370	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OPI30_RS01375	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OPI30_RS01380	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OPI30_RS01385	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OPI30_RS01390	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OPI30_RS01395	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OPI30_RS01400	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OPI30_RS01405	COG1841	ribosomal large subunit assembly
OPI30_RS01410	COG0200	Binds to the 23S rRNA
OPI30_RS01415	COG0201	protein transport
OPI30_RS01420	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OPI30_RS01425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OPI30_RS01430	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OPI30_RS01435	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OPI30_RS01440	COG0202	RNA polymerase activity
OPI30_RS01445	COG0203	ribosomal protein L17
OPI30_RS01485	COG1484	DNA-dependent DNA replication
OPI30_RS01540	COG1358	cellular component organization or biogenesis
OPI30_RS01645	COG3385	transposase activity
OPI30_RS01655	COG3655	Transcriptional regulator
OPI30_RS01725	COG2249	NAD(P)H dehydrogenase (quinone) activity
OPI30_RS01730	COG0583	DNA-binding transcription factor activity
OPI30_RS01735	COG4221	oxidoreductase activity
OPI30_RS01750	COG1770	oligopeptidase
OPI30_RS01755	COG2358	TRAP transporter, solute receptor (TAXI family
OPI30_RS01770	COG3714	YhhN family
OPI30_RS01785	COG0583	DNA-binding transcription factor activity
OPI30_RS01795	COG1301	dicarboxylic acid transport
OPI30_RS01805	COG2095	MarC family integral membrane protein
OPI30_RS01815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OPI30_RS01825	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OPI30_RS01835	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OPI30_RS01860	COG0742	ribosomal rna small subunit methyltransferase
OPI30_RS01865	COG0552	protein localization to endoplasmic reticulum
OPI30_RS01870	COG2884	Cell division ATP-binding protein ftsE
OPI30_RS01875	COG2177	Part of the ABC transporter FtsEX involved in
OPI30_RS01885	COG0288	reversible hydration of carbon dioxide
OPI30_RS01890	COG2188	Transcriptional regulator
OPI30_RS01895	COG3385	transposase activity
OPI30_RS01900	COG1228	amidohydrolase
OPI30_RS01905	COG0010	Belongs to the arginase family
OPI30_RS01910	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OPI30_RS01915	COG2986	histidine ammonia-lyase
OPI30_RS01920	COG0387	Pfam Sodium calcium exchanger
OPI30_RS01925	COG2200	EAL domain
OPI30_RS01965	COG3409	Peptidoglycan-binding domain 1 protein
OPI30_RS01965	COG3267	Type II secretory pathway component ExeA
OPI30_RS01975	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OPI30_RS01980	COG1459	type II secretion system
OPI30_RS02000	COG4968	Prepilin-type N-terminal cleavage methylation domain
OPI30_RS02025	COG3385	transposase activity
OPI30_RS02035	COG5433	transposase activity
OPI30_RS02045	COG1077	Cell shape determining protein MreB Mrl
OPI30_RS02050	COG1792	Involved in formation and maintenance of cell shape
OPI30_RS02055	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OPI30_RS02060	COG0424	maF-like protein
OPI30_RS02065	COG1530	ribonuclease E activity
OPI30_RS02070	COG3164	Protein of unknown function
OPI30_RS02075	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OPI30_RS02080	COG0312	modulator of DNA gyrase
OPI30_RS02095	COG0477	Major facilitator Superfamily
OPI30_RS02105	COG2321	neutral zinc metallopeptidase
OPI30_RS02115	COG0675	Transposase, IS605 OrfB family
OPI30_RS02150	COG0189	ligase activity
OPI30_RS02155	COG0642	Histidine kinase
OPI30_RS02160	COG0745	RESPONSE REGULATOR receiver
OPI30_RS02175	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OPI30_RS02185	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OPI30_RS02195	COG2022	thiamine diphosphate biosynthetic process
OPI30_RS02200	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OPI30_RS02215	COG3932	Exopolysaccharide synthesis, ExoD
OPI30_RS02225	COG5433	transposase activity
OPI30_RS02240	COG1733	regulation of RNA biosynthetic process
OPI30_RS02260	COG1214	PFAM Peptidase M22, glycoprotease
OPI30_RS02260	COG0456	acetyltransferase
OPI30_RS02265	COG2226	methyltransferase
OPI30_RS02280	COG3385	transposase activity
OPI30_RS02305	COG1494	fructose-1,6-bisphosphatase
OPI30_RS02315	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OPI30_RS02320	COG5007	Belongs to the BolA IbaG family
OPI30_RS02330	COG2854	intermembrane phospholipid transfer
OPI30_RS02335	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OPI30_RS02340	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OPI30_RS02345	COG1127	ABC transporter
OPI30_RS02350	COG0517	IMP dehydrogenase activity
OPI30_RS02350	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OPI30_RS02355	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OPI30_RS02365	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OPI30_RS02370	COG1137	ATPase activity
OPI30_RS02375	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OPI30_RS02385	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPI30_RS02390	COG1660	Displays ATPase and GTPase activities
OPI30_RS02395	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPI30_RS02435	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPI30_RS02440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OPI30_RS02450	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OPI30_RS02455	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OPI30_RS02460	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OPI30_RS02465	COG0723	plastoquinol--plastocyanin reductase activity
OPI30_RS02470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OPI30_RS02475	COG2857	Cytochrome c1
OPI30_RS02480	COG0625	glutathione transferase activity
OPI30_RS02485	COG2969	positive regulation of protein catabolic process
OPI30_RS02490	COG2823	Periplasmic or secreted lipoprotein
OPI30_RS02495	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OPI30_RS02500	COG0792	nuclease activity
OPI30_RS02505	COG3107	peptidoglycan biosynthetic process
OPI30_RS02510	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OPI30_RS02520	COG2001	Belongs to the MraZ family
OPI30_RS02525	COG0275	rRNA processing
OPI30_RS02530	COG3116	cell division
OPI30_RS02535	COG0768	penicillin binding
OPI30_RS02540	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OPI30_RS02545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OPI30_RS02550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OPI30_RS02555	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OPI30_RS02560	COG0772	Belongs to the SEDS family
OPI30_RS02565	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OPI30_RS02570	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OPI30_RS02575	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OPI30_RS02580	COG0849	cell division
OPI30_RS02585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OPI30_RS02590	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OPI30_RS02600	COG0653	protein targeting
OPI30_RS02610	COG0494	nUDIX hydrolase
OPI30_RS02615	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OPI30_RS02620	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
OPI30_RS02630	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OPI30_RS02635	COG1459	type II secretion system
OPI30_RS02675	COG2186	Transcriptional regulator
OPI30_RS02680	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OPI30_RS02685	COG0508	dehydrogenase complex catalyzes the overall conversion of
OPI30_RS02690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OPI30_RS02700	COG0840	transmembrane signaling receptor activity
OPI30_RS02705	COG0840	transmembrane signaling receptor activity
OPI30_RS02710	COG1752	Esterase of the alpha-beta hydrolase superfamily
OPI30_RS02715	COG1049	propionate catabolic process, 2-methylcitrate cycle
OPI30_RS02720	COG2200	EAL domain
OPI30_RS02730	COG1280	lysine exporter protein (LysE YggA)
OPI30_RS02740	COG0523	cobalamin synthesis protein
OPI30_RS02745	COG0477	Major facilitator Superfamily
OPI30_RS02760	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OPI30_RS02765	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OPI30_RS02820	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OPI30_RS02830	COG1546	Belongs to the CinA family
OPI30_RS02835	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OPI30_RS02840	COG2137	regulation of response to DNA damage stimulus
OPI30_RS02845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OPI30_RS02850	COG0527	aspartate kinase activity
OPI30_RS02855	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OPI30_RS02890	COG1686	Belongs to the peptidase S11 family
OPI30_RS02895	COG0586	Pfam SNARE associated Golgi protein
OPI30_RS02900	COG1253	flavin adenine dinucleotide binding
OPI30_RS02905	COG0525	valine-tRNA ligase activity
OPI30_RS02910	COG2927	DNA polymerase III (CHI subunit)
OPI30_RS02915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OPI30_RS02920	COG0795	lipopolysaccharide-transporting ATPase activity
OPI30_RS02925	COG0795	lipopolysaccharide-transporting ATPase activity
OPI30_RS02940	COG4974	Belongs to the 'phage' integrase family
OPI30_RS02945	COG3039	Transposase
OPI30_RS02990	COG0004	ammonium transporteR
OPI30_RS02995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPI30_RS03015	COG0084	hydrolase, TatD family'
OPI30_RS03020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OPI30_RS03030	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OPI30_RS03035	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OPI30_RS03040	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OPI30_RS03045	COG0813	purine-nucleoside phosphorylase activity
OPI30_RS03050	COG5002	protein histidine kinase activity
OPI30_RS03050	COG5001	Diguanylate cyclase
OPI30_RS03050	COG3447	MASE1 domain protein
OPI30_RS03060	COG0560	Phosphoserine phosphatase
OPI30_RS03075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OPI30_RS03085	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
OPI30_RS03090	COG0776	regulation of translation
OPI30_RS03110	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPI30_RS03115	COG0735	belongs to the Fur family
OPI30_RS03135	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OPI30_RS03140	COG0513	Belongs to the DEAD box helicase family
OPI30_RS03145	COG3022	response to hydroperoxide
OPI30_RS03160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OPI30_RS03165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OPI30_RS03170	COG0762	integral membrane protein
OPI30_RS03175	COG1872	DUF167
OPI30_RS03195	COG3112	Uncharacterised protein family (UPF0231)
OPI30_RS03200	COG3835	regulator
OPI30_RS03205	COG2610	gluconate transmembrane transporter activity
OPI30_RS03210	COG1929	Belongs to the glycerate kinase type-1 family
OPI30_RS03225	COG0583	DNA-binding transcription factor activity
OPI30_RS03230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OPI30_RS03245	COG0347	Belongs to the P(II) protein family
OPI30_RS03250	COG1840	ABC-type Fe3 transport system, periplasmic component
OPI30_RS03260	COG3842	ATPase activity
OPI30_RS03265	COG2837	iron assimilation
OPI30_RS03270	COG1438	arginine binding
OPI30_RS03275	COG1126	abc transporter atp-binding protein
OPI30_RS03280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS03285	COG4215	(ABC) transporter
OPI30_RS03290	COG4160	amino acid transport
OPI30_RS03295	COG0039	L-malate dehydrogenase activity
OPI30_RS03300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
OPI30_RS03305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPI30_RS03305	COG1017	nitric oxide dioxygenase activity
OPI30_RS03315	COG3385	transposase activity
OPI30_RS03320	COG4536	flavin adenine dinucleotide binding
OPI30_RS03325	COG4137	Cytochrome C assembly protein
OPI30_RS03330	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OPI30_RS03340	COG0228	four-way junction DNA binding
OPI30_RS03345	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OPI30_RS03350	COG0336	Belongs to the RNA methyltransferase TrmD family
OPI30_RS03355	COG0335	large ribosomal subunit rRNA binding
OPI30_RS03375	COG1051	belongs to the nudix hydrolase family
OPI30_RS03385	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OPI30_RS03390	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OPI30_RS03395	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OPI30_RS03405	COG0583	DNA-binding transcription factor activity
OPI30_RS03410	COG0640	Transcriptional regulator
OPI30_RS03415	COG0268	Binds directly to 16S ribosomal RNA
OPI30_RS03420	COG0728	peptidoglycan biosynthetic process
OPI30_RS03425	COG0196	riboflavin kinase activity
OPI30_RS03430	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OPI30_RS03435	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OPI30_RS03440	COG1047	Peptidyl-prolyl cis-trans
OPI30_RS03445	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OPI30_RS03450	COG3385	transposase activity
OPI30_RS03500	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OPI30_RS03500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OPI30_RS03515	COG1854	S-ribosylhomocysteine lyase activity
OPI30_RS03520	COG3385	transposase activity
OPI30_RS03525	COG3706	GGDEF domain
OPI30_RS03530	COG0557	exoribonuclease II activity
OPI30_RS03535	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OPI30_RS03545	COG2153	protein acetylation
OPI30_RS03555	COG1914	H( )-stimulated, divalent metal cation uptake system
OPI30_RS03560	COG0360	Binds together with S18 to 16S ribosomal RNA
OPI30_RS03565	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OPI30_RS03570	COG0359	binds to the 23S rRNA
OPI30_RS03610	COG1238	metal cluster binding
OPI30_RS03615	COG0612	Peptidase, M16
OPI30_RS03620	COG2918	glutathione biosynthetic process
OPI30_RS03625	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OPI30_RS03630	COG1027	Aspartate ammonia-lyase
OPI30_RS03635	COG3030	protein affecting phage T7 exclusion by the F plasmid
OPI30_RS03640	COG0534	Mate efflux family protein
OPI30_RS03645	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OPI30_RS03650	COG0459	protein refolding
OPI30_RS03670	COG0564	pseudouridine synthase activity
OPI30_RS03675	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OPI30_RS03730	COG5433	transposase activity
OPI30_RS03745	COG3328	transposase activity
OPI30_RS03765	COG0784	Response regulator, receiver
OPI30_RS03765	COG0835	chemotaxis
OPI30_RS03780	COG2203	Gaf domain
OPI30_RS03780	COG4251	negative regulation of phosphorylation
OPI30_RS03780	COG5001	Diguanylate cyclase
OPI30_RS03780	COG3706	GGDEF domain
OPI30_RS03810	COG3397	chitin binding
OPI30_RS03815	COG0840	transmembrane signaling receptor activity
OPI30_RS03845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OPI30_RS03860	COG1448	Aminotransferase
OPI30_RS03870	COG2194	sulfuric ester hydrolase activity
OPI30_RS03880	COG2194	sulfuric ester hydrolase activity
OPI30_RS03910	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OPI30_RS03915	COG0457	Tetratricopeptide repeat
OPI30_RS03915	COG3118	belongs to the thioredoxin family
OPI30_RS03965	COG0513	Belongs to the DEAD box helicase family
OPI30_RS03970	COG0840	transmembrane signaling receptor activity
OPI30_RS03980	COG4166	transmembrane transport
OPI30_RS03995	COG1024	Enoyl-CoA hydratase
OPI30_RS04010	COG4221	oxidoreductase activity
OPI30_RS04015	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OPI30_RS04020	COG0442	prolyl-tRNA aminoacylation
OPI30_RS04030	COG0632	four-way junction helicase activity
OPI30_RS04035	COG2255	four-way junction helicase activity
OPI30_RS04045	COG1271	oxidase subunit
OPI30_RS04050	COG1294	oxidase, subunit
OPI30_RS04055	COG4890	Cyd operon protein YbgT
OPI30_RS04060	COG3790	cyd operon protein YbgE
OPI30_RS04065	COG0824	Thioesterase
OPI30_RS04070	COG0811	peptide transport
OPI30_RS04085	COG0823	Involved in the tonB-independent uptake of proteins
OPI30_RS04090	COG2885	chlorophyll binding
OPI30_RS04095	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
OPI30_RS04170	COG0840	transmembrane signaling receptor activity
OPI30_RS04175	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OPI30_RS04180	COG0676	glucose-6-phosphate 1-epimerase activity
OPI30_RS04185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OPI30_RS04190	COG1640	4-alpha-glucanotransferase
OPI30_RS04195	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OPI30_RS04225	COG2130	NADP-dependent
OPI30_RS04230	COG1846	Transcriptional regulator
OPI30_RS04260	COG0561	phosphatase activity
OPI30_RS04275	COG0733	neurotransmitter:sodium symporter activity
OPI30_RS04280	COG0733	neurotransmitter:sodium symporter activity
OPI30_RS04295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPI30_RS04310	COG1794	racemase activity, acting on amino acids and derivatives
OPI30_RS04320	COG1022	Amp-dependent synthetase and ligase
OPI30_RS04330	COG0456	acetyltransferase
OPI30_RS04345	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OPI30_RS04350	COG5001	Diguanylate cyclase
OPI30_RS04350	COG5002	protein histidine kinase activity
OPI30_RS04385	COG1902	pentaerythritol trinitrate reductase activity
OPI30_RS04400	COG2957	Belongs to the agmatine deiminase family
OPI30_RS04405	COG0154	amidase activity
OPI30_RS04415	COG5433	transposase activity
OPI30_RS04445	COG3328	transposase activity
OPI30_RS04480	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
OPI30_RS04490	COG0577	efflux transmembrane transporter activity
OPI30_RS04490	COG1136	(ABC) transporter
OPI30_RS04495	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS04500	COG0745	RESPONSE REGULATOR receiver
OPI30_RS04505	COG2205	protein histidine kinase activity
OPI30_RS04555	COG3335	DDE superfamily endonuclease
OPI30_RS04565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPI30_RS04575	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OPI30_RS04585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
OPI30_RS04590	COG1178	ABC-type Fe3 transport system permease component
OPI30_RS04595	COG4143	(ABC) transporter
OPI30_RS04610	COG0066	3-isopropylmalate dehydratase activity
OPI30_RS04615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OPI30_RS04620	COG0473	3-isopropylmalate dehydrogenase activity
OPI30_RS04625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OPI30_RS04635	COG0671	phosphoesterase, PA-phosphatase related
OPI30_RS04650	COG0028	Belongs to the TPP enzyme family
OPI30_RS04655	COG0440	acetolactate synthase activity
OPI30_RS04665	COG0280	phosphate acetyltransferase
OPI30_RS04665	COG0857	belongs to the CobB CobQ family
OPI30_RS04670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OPI30_RS04680	COG3013	Belongs to the UPF0304 family
OPI30_RS04685	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OPI30_RS04690	COG2716	regulation of RNA biosynthetic process
OPI30_RS04695	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPI30_RS04700	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
OPI30_RS04705	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OPI30_RS04720	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OPI30_RS04740	COG2198	Histidine kinase
OPI30_RS04740	COG5002	protein histidine kinase activity
OPI30_RS04740	COG0784	Response regulator, receiver
OPI30_RS04760	COG0784	Response regulator, receiver
OPI30_RS04760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS04760	COG2198	Histidine kinase
OPI30_RS04760	COG2205	protein histidine kinase activity
OPI30_RS04770	COG0840	transmembrane signaling receptor activity
OPI30_RS04780	COG1464	Belongs to the NlpA lipoprotein family
OPI30_RS04785	COG2011	ABC-type metal ion transport system permease component
OPI30_RS04790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OPI30_RS04810	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OPI30_RS04810	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OPI30_RS04815	COG0802	atpase or kinase
OPI30_RS04825	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OPI30_RS04830	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OPI30_RS04835	COG1923	regulation of RNA biosynthetic process
OPI30_RS04840	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OPI30_RS04845	COG0330	HflC and HflK could
OPI30_RS04850	COG0330	HflC and HflK could
OPI30_RS04855	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
OPI30_RS04860	COG0142	geranyltranstransferase activity
OPI30_RS04865	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OPI30_RS04870	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OPI30_RS04875	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OPI30_RS04880	COG3314	Sporulation integral membrane protein YlbJ
OPI30_RS04885	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OPI30_RS04890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OPI30_RS04900	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OPI30_RS04905	COG2967	ApaG domain
OPI30_RS04910	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OPI30_RS04915	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OPI30_RS04925	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OPI30_RS04930	COG3178	'Phosphotransferase
OPI30_RS04935	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OPI30_RS04940	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OPI30_RS04945	COG2252	PERMEase
OPI30_RS04955	COG0488	(ABC) transporter
OPI30_RS04960	COG0582	viral genome integration into host DNA
OPI30_RS05010	COG2314	TM2 domain
OPI30_RS05060	COG1846	Transcriptional regulator
OPI30_RS05075	COG3646	Phage regulatory protein
OPI30_RS05125	COG1802	Transcriptional regulator
OPI30_RS05125	COG4626	Terminase
OPI30_RS05250	COG0741	lytic transglycosylase activity
OPI30_RS05255	COG0463	Glycosyl transferase, family 2
OPI30_RS05265	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OPI30_RS05290	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPI30_RS05300	COG3721	Heme iron utilization protein
OPI30_RS05305	COG0748	coenzyme F420 binding
OPI30_RS05330	COG2814	Major facilitator Superfamily
OPI30_RS05335	COG2202	Pas domain
OPI30_RS05335	COG2205	protein histidine kinase activity
OPI30_RS05345	COG2226	methyltransferase
OPI30_RS05355	COG1765	OsmC-like protein
OPI30_RS05370	COG3954	Phosphoribulokinase
OPI30_RS05375	COG3089	Belongs to the UPF0270 family
OPI30_RS05380	COG4251	negative regulation of phosphorylation
OPI30_RS05380	COG2203	Gaf domain
OPI30_RS05380	COG3706	GGDEF domain
OPI30_RS05380	COG5001	Diguanylate cyclase
OPI30_RS05385	COG0429	hydrolase of the alpha beta-hydrolase fold
OPI30_RS05390	COG0784	Response regulator, receiver
OPI30_RS05390	COG0835	chemotaxis
OPI30_RS05400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OPI30_RS05405	COG1047	Peptidyl-prolyl cis-trans
OPI30_RS05410	COG2900	Belongs to the SlyX family
OPI30_RS05420	COG0545	Peptidyl-prolyl cis-trans isomerase
OPI30_RS05425	COG2204	response regulator
OPI30_RS05460	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPI30_RS05465	COG3385	transposase activity
OPI30_RS05470	COG0506	proline dehydrogenase activity
OPI30_RS05470	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OPI30_RS05470	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OPI30_RS05480	COG0114	fumarate hydratase activity
OPI30_RS05490	COG1566	PFAM secretion protein HlyD family protein
OPI30_RS05560	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OPI30_RS05575	COG1280	lysine exporter protein (LysE YggA)
OPI30_RS05580	COG0826	peptidase U32
OPI30_RS05590	COG3813	Protein conserved in bacteria
OPI30_RS05610	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OPI30_RS05635	COG0300	oxidoreductase activity
OPI30_RS05655	COG2610	gluconate transmembrane transporter activity
OPI30_RS05660	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OPI30_RS05665	COG3622	Belongs to the hyi family
OPI30_RS05670	COG0235	Class ii aldolase
OPI30_RS05675	COG3395	kinase activity
OPI30_RS05680	COG2084	Dehydrogenase
OPI30_RS05685	COG1349	DNA-binding transcription factor activity
OPI30_RS05695	COG2133	pyrroloquinoline quinone binding
OPI30_RS05720	COG3385	transposase activity
OPI30_RS05760	COG5377	YqaJ viral recombinase family
OPI30_RS05790	COG0077	Prephenate dehydratase
OPI30_RS05790	COG1605	Chorismate mutase
OPI30_RS05815	COG3272	Protein of unknown function (DUF1722)
OPI30_RS05820	COG0789	Transcriptional regulator
OPI30_RS05825	COG0415	Belongs to the DNA photolyase family
OPI30_RS05835	COG4221	oxidoreductase activity
OPI30_RS05850	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OPI30_RS05875	COG0783	Belongs to the Dps family
OPI30_RS05880	COG1151	hydroxylamine reductase activity
OPI30_RS05890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OPI30_RS05905	COG3012	SEC-C Motif Domain Protein
OPI30_RS05905	COG3318	Belongs to the UPF0149 family
OPI30_RS05915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPI30_RS05925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPI30_RS05930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS05980	COG5433	transposase activity
OPI30_RS06045	COG2273	Hydrolase Family 16
OPI30_RS06045	COG5297	Belongs to the glycosyl hydrolase family 6
OPI30_RS06050	COG1472	Belongs to the glycosyl hydrolase 3 family
OPI30_RS06055	COG0840	transmembrane signaling receptor activity
OPI30_RS06060	COG2182	Extracellular solute-binding protein
OPI30_RS06065	COG1609	Transcriptional regulator
OPI30_RS06095	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS06105	COG5000	phosphorelay sensor kinase activity
OPI30_RS06105	COG5002	protein histidine kinase activity
OPI30_RS06110	COG0659	secondary active sulfate transmembrane transporter activity
OPI30_RS06125	COG1666	GTP binding
OPI30_RS06130	COG3248	Nucleoside-binding outer membrane protein
OPI30_RS06135	COG2211	Major facilitator Superfamily
OPI30_RS06145	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPI30_RS06155	COG2813	Specifically methylates the guanine in position
OPI30_RS06160	COG0271	Belongs to the BolA IbaG family
OPI30_RS06165	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OPI30_RS06170	COG1805	sodium ion transport
OPI30_RS06175	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OPI30_RS06180	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OPI30_RS06185	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OPI30_RS06190	COG2871	sodium ion transport
OPI30_RS06195	COG1477	protein flavinylation
OPI30_RS06210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OPI30_RS06215	COG0840	transmembrane signaling receptor activity
OPI30_RS06220	COG0583	DNA-binding transcription factor activity
OPI30_RS06235	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OPI30_RS06245	COG0473	3-isopropylmalate dehydrogenase activity
OPI30_RS06250	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OPI30_RS06255	COG1611	Belongs to the LOG family
OPI30_RS06270	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OPI30_RS06270	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OPI30_RS06280	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
OPI30_RS06305	COG3098	single-species biofilm formation
OPI30_RS06310	COG0564	pseudouridine synthase activity
OPI30_RS06325	COG4580	involved in the transport of maltose and maltodextrins
OPI30_RS06335	COG1263	PTS System
OPI30_RS06335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OPI30_RS06345	COG2171	N-acyltransferase activity
OPI30_RS06350	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OPI30_RS06355	COG0024	Methionine aminopeptidase
OPI30_RS06360	COG0052	Belongs to the universal ribosomal protein uS2 family
OPI30_RS06365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OPI30_RS06370	COG0528	UMP kinase activity
OPI30_RS06375	COG0233	cytoplasmic translational termination
OPI30_RS06380	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OPI30_RS06385	COG0575	Belongs to the CDS family
OPI30_RS06390	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OPI30_RS06395	COG0750	zinc metalloprotease
OPI30_RS06410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OPI30_RS06415	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OPI30_RS06420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OPI30_RS06425	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OPI30_RS06430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OPI30_RS06440	COG0825	malonyl-CoA metabolic process
OPI30_RS06455	COG0814	amino acid
OPI30_RS06460	COG0531	amino acid
OPI30_RS06475	COG0488	(ABC) transporter
OPI30_RS06485	COG3590	peptidase
OPI30_RS06490	COG0037	tRNA processing
OPI30_RS06495	COG3706	GGDEF domain
OPI30_RS06530	COG0366	Alpha amylase catalytic
OPI30_RS06545	COG0463	Glycosyl transferase, family 2
OPI30_RS06560	COG2989	Protein conserved in bacteria
OPI30_RS06565	COG3108	Peptidase M15
OPI30_RS06575	COG2860	membrane
OPI30_RS06585	COG1196	nuclear chromosome segregation
OPI30_RS06590	COG3115	cell septum assembly
OPI30_RS06595	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OPI30_RS06605	COG1328	CTP reductase activity
OPI30_RS06610	COG0602	queuosine metabolic process
OPI30_RS06640	COG1566	PFAM secretion protein HlyD family protein
OPI30_RS06650	COG3290	protein histidine kinase activity
OPI30_RS06665	COG0667	Aldo Keto reductase
OPI30_RS06670	COG0697	spore germination
OPI30_RS06690	COG3284	Transcriptional regulator
OPI30_RS06700	COG3706	GGDEF domain
OPI30_RS06705	COG0346	lactoylglutathione lyase activity
OPI30_RS06710	COG0745	RESPONSE REGULATOR receiver
OPI30_RS06715	COG5002	protein histidine kinase activity
OPI30_RS06725	COG4783	chaperone-mediated protein folding
OPI30_RS06735	COG1940	carbohydrate kinase activity
OPI30_RS06740	COG3142	Participates in the control of copper homeostasis
OPI30_RS06765	COG0545	Peptidyl-prolyl cis-trans isomerase
OPI30_RS06770	COG1131	(ABC) transporter
OPI30_RS06785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS06790	COG4597	amino acid ABC transporter
OPI30_RS06795	COG0765	amino acid transport
OPI30_RS06800	COG1126	abc transporter atp-binding protein
OPI30_RS06810	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OPI30_RS06815	COG0678	peroxiredoxin activity
OPI30_RS06825	COG0019	diaminopimelate decarboxylase activity
OPI30_RS06830	COG1115	amino acid carrier protein
OPI30_RS06835	COG0095	Lipoate-protein ligase
OPI30_RS06860	COG2207	Transcriptional regulator
OPI30_RS06865	COG0281	malic enzyme
OPI30_RS06895	COG0733	neurotransmitter:sodium symporter activity
OPI30_RS06900	COG1752	Esterase of the alpha-beta hydrolase superfamily
OPI30_RS06905	COG3706	GGDEF domain
OPI30_RS06915	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPI30_RS06920	COG1032	radical SAM domain protein
OPI30_RS06930	COG3335	DDE superfamily endonuclease
OPI30_RS06940	COG3385	transposase activity
OPI30_RS06955	COG3385	transposase activity
OPI30_RS07030	COG0673	inositol 2-dehydrogenase activity
OPI30_RS07035	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OPI30_RS07040	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OPI30_RS07055	COG1196	nuclear chromosome segregation
OPI30_RS07055	COG0741	lytic transglycosylase activity
OPI30_RS07055	COG0739	heme binding
OPI30_RS07080	COG0788	formyltetrahydrofolate deformylase activity
OPI30_RS07085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OPI30_RS07095	COG3118	belongs to the thioredoxin family
OPI30_RS07105	COG0791	NLP P60 protein
OPI30_RS07110	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
OPI30_RS07125	COG1388	LysM domain
OPI30_RS07125	COG1376	ErfK ybiS ycfS ynhG family protein
OPI30_RS07135	COG2205	protein histidine kinase activity
OPI30_RS07135	COG0784	Response regulator, receiver
OPI30_RS07160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS07160	COG2205	protein histidine kinase activity
OPI30_RS07170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS07170	COG2205	protein histidine kinase activity
OPI30_RS07175	COG3384	dioxygenase
OPI30_RS07185	COG1283	sodium-dependent phosphate transmembrane transporter activity
OPI30_RS07195	COG0531	amino acid
OPI30_RS07200	COG0531	amino acid
OPI30_RS07215	COG1012	belongs to the aldehyde dehydrogenase family
OPI30_RS07220	COG1917	Cupin 2, conserved barrel domain protein
OPI30_RS07220	COG1396	sequence-specific DNA binding
OPI30_RS07225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OPI30_RS07265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OPI30_RS07265	COG4651	solute:proton antiporter activity
OPI30_RS07280	COG2974	May be involved in recombination
OPI30_RS07285	COG1247	-acetyltransferase
OPI30_RS07290	COG0420	3'-5' exonuclease activity
OPI30_RS07305	COG3038	cytochrome b561
OPI30_RS07310	COG2190	(PTS) system
OPI30_RS07320	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPI30_RS07325	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OPI30_RS07330	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OPI30_RS07345	COG1720	tRNA m6t6A37 methyltransferase activity
OPI30_RS07365	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OPI30_RS07370	COG4988	ABC transporter
OPI30_RS07385	COG0745	RESPONSE REGULATOR receiver
OPI30_RS07395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OPI30_RS07410	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OPI30_RS07415	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
OPI30_RS07425	COG0083	homoserine kinase activity
OPI30_RS07430	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OPI30_RS07435	COG4319	ketosteroid isomerase
OPI30_RS07450	COG3039	Transposase
OPI30_RS07460	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OPI30_RS07470	COG3220	belongs to the UPF0276 family
OPI30_RS07500	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OPI30_RS07505	COG1289	transmembrane transporter activity
OPI30_RS07510	COG1763	Mo-molybdopterin cofactor biosynthetic process
OPI30_RS07515	COG0746	molybdenum cofactor guanylyltransferase activity
OPI30_RS07520	COG0281	malic enzyme
OPI30_RS07555	COG3264	Mechanosensitive ion channel
OPI30_RS07555	COG1196	nuclear chromosome segregation
OPI30_RS07565	COG2850	peptidyl-arginine hydroxylation
OPI30_RS07570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OPI30_RS07575	COG2915	High frequency lysogenization protein hflD homolog
OPI30_RS07580	COG0482	sulfurtransferase activity
OPI30_RS07590	COG1187	pseudouridine synthase activity
OPI30_RS07595	COG0456	acetyltransferase
OPI30_RS07630	COG0538	isocitrate dehydrogenase activity
OPI30_RS07640	COG3048	D-serine ammonia-lyase activity
OPI30_RS07645	COG0583	DNA-binding transcription factor activity
OPI30_RS07650	COG2916	Histone family protein nucleoid-structuring protein H-NS
OPI30_RS07660	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OPI30_RS07665	COG2375	cellular response to nickel ion
OPI30_RS07670	COG1538	Outer membrane efflux protein
OPI30_RS07675	COG1136	(ABC) transporter
OPI30_RS07675	COG0577	efflux transmembrane transporter activity
OPI30_RS07680	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS07690	COG0497	DNA recombination
OPI30_RS07695	COG3706	GGDEF domain
OPI30_RS07700	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OPI30_RS07705	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OPI30_RS07710	COG0443	Heat shock 70 kDa protein
OPI30_RS07715	COG0484	heat shock protein binding
OPI30_RS07745	COG1285	pathogenesis
OPI30_RS07755	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPI30_RS07765	COG0640	Transcriptional regulator
OPI30_RS07795	COG0095	Lipoate-protein ligase
OPI30_RS07810	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPI30_RS07815	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS07825	COG0708	Exodeoxyribonuclease III
OPI30_RS07835	COG0745	RESPONSE REGULATOR receiver
OPI30_RS07850	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OPI30_RS07865	COG1846	Transcriptional regulator
OPI30_RS07885	COG0583	DNA-binding transcription factor activity
OPI30_RS07890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPI30_RS07895	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OPI30_RS07900	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OPI30_RS07905	COG1845	cytochrome c oxidase, subunit III
OPI30_RS07910	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OPI30_RS07915	COG0109	protoheme IX farnesyltransferase activity
OPI30_RS07920	COG2814	Major facilitator Superfamily
OPI30_RS07925	COG5507	3-demethylubiquinone-9 3-methyltransferase
OPI30_RS07935	COG2175	clavaminate synthase activity
OPI30_RS07940	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OPI30_RS07945	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
OPI30_RS07950	COG4521	taurine ABC transporter
OPI30_RS07980	COG3550	peptidyl-serine autophosphorylation
OPI30_RS07985	COG1396	sequence-specific DNA binding
OPI30_RS07990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OPI30_RS07995	COG0159	tryptophan synthase activity
OPI30_RS08000	COG0133	tryptophan synthase activity
OPI30_RS08005	COG0134	indole-3-glycerol-phosphate synthase activity
OPI30_RS08005	COG0135	phosphoribosylanthranilate isomerase activity
OPI30_RS08010	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OPI30_RS08015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OPI30_RS08015	COG0512	Glutamine amidotransferase of anthranilate synthase
OPI30_RS08020	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OPI30_RS08025	COG0613	PHP domain protein
OPI30_RS08030	COG0009	L-threonylcarbamoyladenylate synthase
OPI30_RS08040	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OPI30_RS08050	COG1946	Acyl-CoA thioesterase
OPI30_RS08065	COG1309	transcriptional regulator
OPI30_RS08070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS08075	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPI30_RS08100	COG5433	transposase activity
OPI30_RS08150	COG2003	Belongs to the UPF0758 family
OPI30_RS08170	COG1484	DNA-dependent DNA replication
OPI30_RS08185	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OPI30_RS08200	COG0583	DNA-binding transcription factor activity
OPI30_RS08255	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OPI30_RS08295	COG2003	Belongs to the UPF0758 family
OPI30_RS08315	COG5377	YqaJ viral recombinase family
OPI30_RS08325	COG3311	Transcriptional regulator
OPI30_RS08355	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OPI30_RS08365	COG1960	acyl-CoA dehydrogenase activity
OPI30_RS08370	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OPI30_RS08380	COG0469	pyruvate kinase activity
OPI30_RS08385	COG1737	Transcriptional regulator
OPI30_RS08425	COG1091	dTDP-4-dehydrorhamnose reductase activity
OPI30_RS08500	COG3385	transposase activity
OPI30_RS08510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OPI30_RS08560	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OPI30_RS08575	COG2244	polysaccharide biosynthetic process
OPI30_RS08600	COG0463	Glycosyl transferase, family 2
OPI30_RS08615	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OPI30_RS08635	COG3132	Protein of unknown function, DUF480
OPI30_RS08675	COG1278	Cold shock
OPI30_RS08705	COG0697	spore germination
OPI30_RS08715	COG0675	Transposase, IS605 OrfB family
OPI30_RS08720	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OPI30_RS08735	COG4166	transmembrane transport
OPI30_RS08740	COG0622	Phosphoesterase
OPI30_RS08755	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
OPI30_RS08760	COG3385	transposase activity
OPI30_RS08765	COG0784	Response regulator, receiver
OPI30_RS08765	COG0835	chemotaxis
OPI30_RS08770	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OPI30_RS08775	COG1815	bacterial-type flagellum-dependent cell motility
OPI30_RS08795	COG4786	Flagellar basal body rod
OPI30_RS08810	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OPI30_RS08815	COG1706	bacterial-type flagellum-dependent cell motility
OPI30_RS08820	COG1705	Flagellar rod assembly protein muramidase FlgJ
OPI30_RS08820	COG3951	Flagellar rod assembly protein muramidase FlgJ
OPI30_RS08845	COG0675	Transposase, IS605 OrfB family
OPI30_RS08860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OPI30_RS08865	COG2716	regulation of RNA biosynthetic process
OPI30_RS08890	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OPI30_RS08895	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OPI30_RS08900	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OPI30_RS08905	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OPI30_RS08930	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OPI30_RS08945	COG0590	tRNA wobble adenosine to inosine editing
OPI30_RS08950	COG0573	inorganic phosphate transmembrane transporter activity
OPI30_RS08955	COG0581	inorganic phosphate transmembrane transporter activity
OPI30_RS08960	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OPI30_RS08965	COG0704	Plays a role in the regulation of phosphate uptake
OPI30_RS08970	COG1253	flavin adenine dinucleotide binding
OPI30_RS08985	COG0531	amino acid
OPI30_RS08995	COG1126	abc transporter atp-binding protein
OPI30_RS09005	COG0765	amino acid transport
OPI30_RS09010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS09030	COG0675	Transposase, IS605 OrfB family
OPI30_RS09035	COG3706	GGDEF domain
OPI30_RS09040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OPI30_RS09060	COG1785	Belongs to the alkaline phosphatase family
OPI30_RS09065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OPI30_RS09070	COG0477	Major facilitator Superfamily
OPI30_RS09075	COG0123	including yeast histone deacetylase and acetoin utilization protein
OPI30_RS09085	COG1199	ATP-dependent helicase activity
OPI30_RS09105	COG1448	Aminotransferase
OPI30_RS09110	COG0433	COG0433 Predicted ATPase
OPI30_RS09125	COG2333	competence protein COMEC
OPI30_RS09125	COG0658	competence protein
OPI30_RS09130	COG1132	(ABC) transporter
OPI30_RS09135	COG1663	tetraacyldisaccharide 4'-kinase activity
OPI30_RS09140	COG2835	tetraacyldisaccharide 4'-kinase activity
OPI30_RS09145	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OPI30_RS09150	COG2197	response regulator
OPI30_RS09155	COG0322	excinuclease ABC activity
OPI30_RS09190	COG0604	alcohol dehydrogenase
OPI30_RS09195	COG1309	transcriptional regulator
OPI30_RS09200	COG2261	transglycosylase associated protein
OPI30_RS09205	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OPI30_RS09215	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OPI30_RS09225	COG2199	diguanylate cyclase activity
OPI30_RS09225	COG2203	Gaf domain
OPI30_RS09275	COG2119	membrane
OPI30_RS09280	COG0023	Translation Initiation Factor
OPI30_RS09290	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OPI30_RS09315	COG4139	cobalamin transport
OPI30_RS09320	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
OPI30_RS09325	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OPI30_RS09330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OPI30_RS09335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OPI30_RS09340	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OPI30_RS09345	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OPI30_RS09355	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OPI30_RS09360	COG0505	Belongs to the CarA family
OPI30_RS09365	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OPI30_RS09375	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OPI30_RS09380	COG3706	GGDEF domain
OPI30_RS09410	COG0513	Belongs to the DEAD box helicase family
OPI30_RS09420	COG4104	PAAR repeat-containing protein
OPI30_RS09440	COG0493	'glutamate synthase
OPI30_RS09445	COG0070	glutamate synthase
OPI30_RS09445	COG0069	glutamate synthase activity
OPI30_RS09445	COG0067	glutamate synthase
OPI30_RS09450	COG1242	4 iron, 4 sulfur cluster binding
OPI30_RS09500	COG1113	amino acid transport
OPI30_RS09510	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OPI30_RS09515	COG0574	Belongs to the PEP-utilizing enzyme family
OPI30_RS09515	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OPI30_RS09520	COG1119	ATPase activity
OPI30_RS09540	COG1464	Belongs to the NlpA lipoprotein family
OPI30_RS09550	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OPI30_RS09555	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OPI30_RS09560	COG3385	transposase activity
OPI30_RS09570	COG0101	tRNA pseudouridine synthase activity
OPI30_RS09575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OPI30_RS09580	COG0285	dihydrofolate synthase activity
OPI30_RS09585	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
OPI30_RS09595	COG2920	part of a sulfur-relay system
OPI30_RS09600	COG1289	transmembrane transporter activity
OPI30_RS09610	COG0670	Belongs to the BI1 family
OPI30_RS09645	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OPI30_RS09650	COG0840	transmembrane signaling receptor activity
OPI30_RS09655	COG5001	Diguanylate cyclase
OPI30_RS09660	COG0564	pseudouridine synthase activity
OPI30_RS09675	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OPI30_RS09685	COG0625	glutathione transferase activity
OPI30_RS09700	COG0367	asparagine synthase
OPI30_RS09710	COG0647	UMP catabolic process
OPI30_RS09715	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OPI30_RS09720	COG0604	alcohol dehydrogenase
OPI30_RS09725	COG1902	pentaerythritol trinitrate reductase activity
OPI30_RS09730	COG1253	flavin adenine dinucleotide binding
OPI30_RS09740	COG0277	FAD linked oxidase domain protein
OPI30_RS09740	COG0247	lactate metabolic process
OPI30_RS09750	COG2050	protein possibly involved in aromatic compounds catabolism
OPI30_RS09770	COG5001	Diguanylate cyclase
OPI30_RS09775	COG0583	DNA-binding transcription factor activity
OPI30_RS09780	COG2814	Major facilitator Superfamily
OPI30_RS09785	COG2056	Na+-H+ antiporter family
OPI30_RS09790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OPI30_RS09805	COG3335	DDE superfamily endonuclease
OPI30_RS09810	COG0483	inositol monophosphate 1-phosphatase activity
OPI30_RS09820	COG0625	glutathione transferase activity
OPI30_RS09825	COG0625	glutathione transferase activity
OPI30_RS09835	COG0601	transmembrane transport
OPI30_RS09840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPI30_RS09845	COG0444	Belongs to the ABC transporter superfamily
OPI30_RS09850	COG2814	Major facilitator Superfamily
OPI30_RS09870	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPI30_RS09875	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPI30_RS09880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OPI30_RS09885	COG0509	glycine decarboxylation via glycine cleavage system
OPI30_RS09890	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OPI30_RS09890	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OPI30_RS09915	COG3634	alkyl hydroperoxide reductase activity
OPI30_RS09920	COG0450	alkyl hydroperoxide reductase
OPI30_RS09925	COG0517	IMP dehydrogenase activity
OPI30_RS09930	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OPI30_RS09935	COG0343	queuine tRNA-ribosyltransferase activity
OPI30_RS09940	COG1862	Preprotein translocase
OPI30_RS09945	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OPI30_RS09950	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OPI30_RS09955	COG2897	thiosulfate sulfurtransferase activity
OPI30_RS09965	COG0826	peptidase U32
OPI30_RS09970	COG0826	peptidase U32
OPI30_RS09975	COG3154	lipid carrier protein
OPI30_RS09990	COG1104	cysteine desulfurase activity
OPI30_RS09995	COG0822	iron-sulfur transferase activity
OPI30_RS10005	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OPI30_RS10010	COG0443	Heat shock 70 kDa protein
OPI30_RS10015	COG0633	Ferredoxin
OPI30_RS10030	COG0105	UTP biosynthetic process
OPI30_RS10035	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OPI30_RS10045	COG1426	Protein conserved in bacteria
OPI30_RS10055	COG0124	histidyl-tRNA synthetase
OPI30_RS10060	COG2976	Protein conserved in bacteria
OPI30_RS10065	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OPI30_RS10070	COG1160	GTP binding
OPI30_RS10075	COG1645	bacterial-type flagellum-dependent swarming motility
OPI30_RS10080	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OPI30_RS10085	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OPI30_RS10085	COG0047	phosphoribosylformylglycinamidine synthase activity
OPI30_RS10095	COG3039	Transposase
OPI30_RS10105	COG1484	DNA-dependent DNA replication
OPI30_RS10110	COG4584	PFAM Integrase catalytic
OPI30_RS10120	COG1007	ATP synthesis coupled electron transport
OPI30_RS10125	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OPI30_RS10135	COG0713	ATP synthesis coupled electron transport
OPI30_RS10140	COG0839	Belongs to the complex I subunit 6 family
OPI30_RS10145	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OPI30_RS10150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OPI30_RS10155	COG1034	ATP synthesis coupled electron transport
OPI30_RS10170	COG0649	NAD binding
OPI30_RS10170	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OPI30_RS10175	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OPI30_RS10180	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OPI30_RS10190	COG1360	Flagellar Motor Protein
OPI30_RS10195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OPI30_RS10220	COG3385	transposase activity
OPI30_RS10225	COG3328	transposase activity
OPI30_RS10240	COG3385	transposase activity
OPI30_RS10255	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OPI30_RS10275	COG3385	transposase activity
OPI30_RS10310	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OPI30_RS10340	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OPI30_RS10360	COG0724	RNA recognition motif
OPI30_RS10365	COG4989	oxidoreductase activity
OPI30_RS10390	COG0745	RESPONSE REGULATOR receiver
OPI30_RS10395	COG0583	DNA-binding transcription factor activity
OPI30_RS10405	COG5433	transposase activity
OPI30_RS10410	COG5001	Diguanylate cyclase
OPI30_RS10410	COG3300	MHYT domain
OPI30_RS10415	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OPI30_RS10445	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OPI30_RS10450	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OPI30_RS10455	COG0539	negative regulation of cytoplasmic translation
OPI30_RS10460	COG0776	regulation of translation
OPI30_RS10470	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OPI30_RS10490	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OPI30_RS10495	COG0602	queuosine metabolic process
OPI30_RS10500	COG3530	Putative quorum-sensing-regulated virulence factor
OPI30_RS10505	COG2096	Adenosyltransferase
OPI30_RS10510	COG2916	Histone family protein nucleoid-structuring protein H-NS
OPI30_RS10515	COG1757	Na H antiporter
OPI30_RS10520	COG1435	thymidine kinase activity
OPI30_RS10630	COG3385	transposase activity
OPI30_RS10640	COG3385	transposase activity
OPI30_RS10645	COG3039	Transposase
OPI30_RS10655	COG3039	Transposase
OPI30_RS10765	COG3039	Transposase
OPI30_RS10775	COG1484	DNA-dependent DNA replication
OPI30_RS10780	COG4584	PFAM Integrase catalytic
OPI30_RS10815	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OPI30_RS10830	COG1397	ADP-ribosylglycohydrolase
OPI30_RS10885	COG3385	transposase activity
OPI30_RS10925	COG3385	transposase activity
OPI30_RS10940	COG2226	methyltransferase
OPI30_RS10980	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OPI30_RS10985	COG0626	cystathionine gamma-synthase activity
OPI30_RS10995	COG2910	NAD(P)H-binding
OPI30_RS11000	COG0583	DNA-binding transcription factor activity
OPI30_RS11005	COG4977	sequence-specific DNA binding
OPI30_RS11005	COG1917	Cupin 2, conserved barrel domain protein
OPI30_RS11010	COG2200	EAL domain
OPI30_RS11015	COG3706	GGDEF domain
OPI30_RS11020	COG4774	siderophore transport
OPI30_RS11030	COG0583	DNA-binding transcription factor activity
OPI30_RS11035	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OPI30_RS11045	COG0617	tRNA 3'-terminal CCA addition
OPI30_RS11045	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OPI30_RS11045	COG0517	IMP dehydrogenase activity
OPI30_RS11050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OPI30_RS11070	COG3088	subunit of a heme lyase
OPI30_RS11070	COG4235	cytochrome complex assembly
OPI30_RS11075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OPI30_RS11080	COG1138	Cytochrome C-type biogenesis protein
OPI30_RS11085	COG3301	Polysulphide reductase, NrfD
OPI30_RS11090	COG0437	4 iron, 4 sulfur cluster binding
OPI30_RS11095	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
OPI30_RS11120	COG0247	lactate metabolic process
OPI30_RS11125	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
OPI30_RS11130	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OPI30_RS11135	COG3012	SEC-C Motif Domain Protein
OPI30_RS11140	COG0840	transmembrane signaling receptor activity
OPI30_RS11145	COG1846	Transcriptional regulator
OPI30_RS11145	COG1940	carbohydrate kinase activity
OPI30_RS11150	COG3290	protein histidine kinase activity
OPI30_RS11155	COG4565	transcriptional regulatory protein
OPI30_RS11170	COG3181	Tripartite tricarboxylate transporter family receptor
OPI30_RS11175	COG1196	nuclear chromosome segregation
OPI30_RS11175	COG0741	lytic transglycosylase activity
OPI30_RS11175	COG0739	heme binding
OPI30_RS11180	COG2985	domain, Protein
OPI30_RS11180	COG0569	domain protein
OPI30_RS11190	COG0556	nucleotide-excision repair
OPI30_RS11200	COG0586	Pfam SNARE associated Golgi protein
OPI30_RS11205	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OPI30_RS11215	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OPI30_RS11220	COG2186	Transcriptional regulator
OPI30_RS11225	COG2719	SpoVR family
OPI30_RS11230	COG2718	Belongs to the UPF0229 family
OPI30_RS11250	COG0514	ATP-dependent DNA helicase (RecQ)
OPI30_RS11255	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OPI30_RS11260	COG0814	amino acid
OPI30_RS11290	COG0058	SHG alpha-glucan phosphorylase activity
OPI30_RS11300	COG0471	metal ion transport
OPI30_RS11305	COG3118	belongs to the thioredoxin family
OPI30_RS11315	COG1132	(ABC) transporter
OPI30_RS11320	COG1132	(ABC) transporter
OPI30_RS11345	COG2501	S4 domain
OPI30_RS11355	COG3243	poly(R)-hydroxyalkanoic acid synthase
OPI30_RS11375	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OPI30_RS11380	COG2329	Antibiotic biosynthesis monooxygenase
OPI30_RS11405	COG1742	UPF0060 membrane protein
OPI30_RS11420	COG0513	Belongs to the DEAD box helicase family
OPI30_RS11425	COG0386	Belongs to the glutathione peroxidase family
OPI30_RS11435	COG1181	Belongs to the D-alanine--D-alanine ligase family
OPI30_RS11440	COG3148	PFAM DTW domain containing protein
OPI30_RS11445	COG0730	response to heat
OPI30_RS11450	COG0583	DNA-binding transcription factor activity
OPI30_RS11470	COG3593	DNA synthesis involved in DNA repair
OPI30_RS11515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OPI30_RS11520	COG1011	Hydrolase
OPI30_RS11525	COG1473	amidohydrolase
OPI30_RS11540	COG0205	6-phosphofructokinase activity
OPI30_RS11550	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OPI30_RS11555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OPI30_RS11565	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
OPI30_RS11570	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OPI30_RS11595	COG0588	phosphoglycerate mutase activity
OPI30_RS11610	COG0675	Transposase, IS605 OrfB family
OPI30_RS11625	COG1280	lysine exporter protein (LysE YggA)
OPI30_RS11640	COG2824	Alkylphosphonate utilization operon protein PhnA
OPI30_RS11675	COG2840	Smr protein MutS2
OPI30_RS11680	COG2890	protein-(glutamine-N5) methyltransferase activity
OPI30_RS11685	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OPI30_RS11695	COG0513	Belongs to the DEAD box helicase family
OPI30_RS11705	COG5654	RES domain protein
OPI30_RS11715	COG0814	amino acid
OPI30_RS11720	COG1609	Transcriptional regulator
OPI30_RS11725	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPI30_RS11725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPI30_RS11730	COG1105	Belongs to the carbohydrate kinase PfkB family
OPI30_RS11735	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OPI30_RS11735	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OPI30_RS11735	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OPI30_RS11740	COG3313	Fe-S protein
OPI30_RS11745	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OPI30_RS11750	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OPI30_RS11755	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPI30_RS11760	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OPI30_RS11770	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OPI30_RS11800	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OPI30_RS11805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OPI30_RS11810	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OPI30_RS11815	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OPI30_RS11820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OPI30_RS11825	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPI30_RS11825	COG0072	phenylalanine-tRNA ligase activity
OPI30_RS11830	COG0776	regulation of translation
OPI30_RS11860	COG3300	MHYT domain
OPI30_RS11860	COG5001	Diguanylate cyclase
OPI30_RS11865	COG1609	Transcriptional regulator
OPI30_RS11870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPI30_RS11875	COG1879	ABC-type sugar transport system periplasmic component
OPI30_RS11880	COG1172	Belongs to the binding-protein-dependent transport system permease family
OPI30_RS11885	COG1129	ABC transporter
OPI30_RS11890	COG1869	D-ribose catabolic process
OPI30_RS11900	COG3385	transposase activity
OPI30_RS11915	COG0675	Transposase, IS605 OrfB family
OPI30_RS11930	COG0037	tRNA processing
OPI30_RS11935	COG0589	response to stress
OPI30_RS11940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OPI30_RS11955	COG2217	Heavy metal translocating P-type atpase
OPI30_RS11965	COG2010	Cytochrome c
OPI30_RS11980	COG3278	Belongs to the heme-copper respiratory oxidase family
OPI30_RS11990	COG1956	GAF domain-containing protein
OPI30_RS11995	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
OPI30_RS12005	COG0308	aminopeptidase N
OPI30_RS12015	COG2902	Dehydrogenase
OPI30_RS12020	COG0167	dihydroorotate dehydrogenase activity
OPI30_RS12030	COG5433	transposase activity
OPI30_RS12035	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OPI30_RS12035	COG0116	Belongs to the methyltransferase superfamily
OPI30_RS12045	COG0488	(ABC) transporter
OPI30_RS12060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OPI30_RS12065	COG1067	ATP-dependent peptidase activity
OPI30_RS12075	COG3141	response to X-ray
OPI30_RS12085	COG2995	paraquat-inducible protein a
OPI30_RS12090	COG3008	intermembrane lipid transfer
OPI30_RS12095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OPI30_RS12095	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OPI30_RS12115	COG0084	hydrolase, TatD family'
OPI30_RS12120	COG0470	DNA polymerase III
OPI30_RS12125	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OPI30_RS12130	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OPI30_RS12135	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OPI30_RS12140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OPI30_RS12145	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OPI30_RS12150	COG1028	Short-chain dehydrogenase reductase Sdr
OPI30_RS12160	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OPI30_RS12165	COG0416	fatty acid biosynthetic process
OPI30_RS12170	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OPI30_RS12175	COG1399	metal-binding, possibly nucleic acid-binding protein
OPI30_RS12190	COG0564	pseudouridine synthase activity
OPI30_RS12195	COG1530	ribonuclease E activity
OPI30_RS12200	COG0306	phosphate transporter
OPI30_RS12205	COG0717	Belongs to the dCTP deaminase family
OPI30_RS12210	COG0572	uridine kinase
OPI30_RS12215	COG0489	protein tyrosine kinase activity
OPI30_RS12220	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPI30_RS12220	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPI30_RS12230	COG1254	Belongs to the acylphosphatase family
OPI30_RS12235	COG0840	transmembrane signaling receptor activity
OPI30_RS12240	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OPI30_RS12255	COG0709	Synthesizes selenophosphate from selenide and ATP
OPI30_RS12260	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
OPI30_RS12265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OPI30_RS12285	COG0784	Response regulator, receiver
OPI30_RS12285	COG2205	protein histidine kinase activity
OPI30_RS12285	COG5002	protein histidine kinase activity
OPI30_RS12290	COG0675	Transposase, IS605 OrfB family
OPI30_RS12310	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OPI30_RS12320	COG1643	Atp-dependent helicase
OPI30_RS12325	COG0517	IMP dehydrogenase activity
OPI30_RS12325	COG0617	tRNA 3'-terminal CCA addition
OPI30_RS12325	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OPI30_RS12330	COG2197	response regulator
OPI30_RS12340	COG3314	Sporulation integral membrane protein YlbJ
OPI30_RS12350	COG0583	DNA-binding transcription factor activity
OPI30_RS12355	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OPI30_RS12365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OPI30_RS12370	COG2832	Protein of unknown function (DUF454)
OPI30_RS12375	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OPI30_RS12385	COG0697	spore germination
OPI30_RS12400	COG0318	PFAM AMP-dependent synthetase and ligase
OPI30_RS12405	COG0596	Alpha beta hydrolase
OPI30_RS12415	COG1214	PFAM Peptidase M22, glycoprotease
OPI30_RS12420	COG1199	ATP-dependent helicase activity
OPI30_RS12430	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OPI30_RS12435	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OPI30_RS12440	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OPI30_RS12445	COG0131	Imidazoleglycerol-phosphate dehydratase
OPI30_RS12445	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OPI30_RS12450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OPI30_RS12455	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OPI30_RS12460	COG3437	response regulator, receiver
OPI30_RS12465	COG2199	diguanylate cyclase activity
OPI30_RS12470	COG0784	Response regulator, receiver
OPI30_RS12470	COG2198	Histidine kinase
OPI30_RS12470	COG2205	protein histidine kinase activity
OPI30_RS12475	COG0107	imidazoleglycerol-phosphate synthase activity
OPI30_RS12480	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OPI30_RS12480	COG0140	phosphoribosyl-ATP diphosphatase activity
OPI30_RS12495	COG0318	PFAM AMP-dependent synthetase and ligase
OPI30_RS12500	COG3134	Outer membrane lipoprotein
OPI30_RS12515	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPI30_RS12540	COG4681	YaeQ
OPI30_RS12550	COG1024	Enoyl-CoA hydratase
OPI30_RS12550	COG1250	3-hydroxyacyl-CoA dehydrogenase
OPI30_RS12555	COG0183	Belongs to the thiolase family
OPI30_RS12560	COG0714	Associated with various cellular activities
OPI30_RS12580	COG2304	oxidoreductase activity
OPI30_RS12590	COG1595	DNA-templated transcription, initiation
OPI30_RS12600	COG2067	long-chain fatty acid transport protein
OPI30_RS12605	COG2067	long-chain fatty acid transport protein
OPI30_RS12610	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OPI30_RS12625	COG1301	dicarboxylic acid transport
OPI30_RS12630	COG3123	guanosine phosphorylase activity
OPI30_RS12635	COG1760	l-serine dehydratase
OPI30_RS12640	COG1760	l-serine dehydratase
OPI30_RS12660	COG3100	YcgL domain-containing protein
OPI30_RS12665	COG3385	transposase activity
OPI30_RS12670	COG0850	regulation of cytokinetic process
OPI30_RS12675	COG2894	cell division
OPI30_RS12680	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OPI30_RS12685	COG3099	Belongs to the UPF0263 family
OPI30_RS12690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OPI30_RS12705	COG2996	Protein conserved in bacteria
OPI30_RS12710	COG0675	Transposase, IS605 OrfB family
OPI30_RS12740	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OPI30_RS12745	COG0697	spore germination
OPI30_RS12750	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OPI30_RS12755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OPI30_RS12770	COG0307	riboflavin synthase, alpha
OPI30_RS12780	COG0534	Mate efflux family protein
OPI30_RS12810	COG0417	DNA replication proofreading
OPI30_RS12825	COG1560	Kdo2-lipid A biosynthetic process
OPI30_RS12830	COG1560	Kdo2-lipid A biosynthetic process
OPI30_RS12840	COG0583	DNA-binding transcription factor activity
OPI30_RS12845	COG0673	inositol 2-dehydrogenase activity
OPI30_RS12850	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OPI30_RS12865	COG0583	DNA-binding transcription factor activity
OPI30_RS12875	COG2723	6-phospho-beta-galactosidase activity
OPI30_RS12880	COG0583	DNA-binding transcription factor activity
OPI30_RS12890	COG0243	molybdopterin cofactor binding
OPI30_RS12895	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OPI30_RS12910	COG0583	DNA-binding transcription factor activity
OPI30_RS12915	COG1879	ABC-type sugar transport system periplasmic component
OPI30_RS12920	COG3385	transposase activity
OPI30_RS12925	COG1129	ABC transporter
OPI30_RS12930	COG1172	Belongs to the binding-protein-dependent transport system permease family
OPI30_RS12935	COG1172	Belongs to the binding-protein-dependent transport system permease family
OPI30_RS12985	COG2003	Belongs to the UPF0758 family
OPI30_RS13025	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OPI30_RS13045	COG0730	response to heat
OPI30_RS13055	COG1028	Short-chain dehydrogenase reductase Sdr
OPI30_RS13065	COG1024	Enoyl-CoA hydratase
OPI30_RS13070	COG1024	Enoyl-CoA hydratase
OPI30_RS13075	COG1960	acyl-CoA dehydrogenase activity
OPI30_RS13085	COG1960	acyl-CoA dehydrogenase activity
OPI30_RS13090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OPI30_RS13095	COG1024	Enoyl-CoA hydratase
OPI30_RS13120	COG1584	GPR1 FUN34 yaaH family protein
OPI30_RS13125	COG3228	Belongs to the MtfA family
OPI30_RS13135	COG1115	amino acid carrier protein
OPI30_RS13140	COG1024	Enoyl-CoA hydratase
OPI30_RS13155	COG3162	membrane
OPI30_RS13160	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPI30_RS13165	COG0488	(ABC) transporter
OPI30_RS13170	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OPI30_RS13175	COG0776	regulation of translation
OPI30_RS13180	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OPI30_RS13185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OPI30_RS13190	COG0740	serine-type endopeptidase activity
OPI30_RS13195	COG0544	peptidyl-prolyl cis-trans isomerase activity
OPI30_RS13205	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OPI30_RS13210	COG4591	ABC-type transport system involved in lipoprotein release permease component
OPI30_RS13215	COG1136	(ABC) transporter
OPI30_RS13220	COG4591	ABC-type transport system involved in lipoprotein release permease component
OPI30_RS13230	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OPI30_RS13235	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OPI30_RS13250	COG0697	spore germination
OPI30_RS13260	COG2062	phosphohistidine phosphatase, SixA
OPI30_RS13280	COG1846	Transcriptional regulator
OPI30_RS13305	COG3039	Transposase
OPI30_RS13310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OPI30_RS13310	COG0519	Catalyzes the synthesis of GMP from XMP
OPI30_RS13315	COG0516	GMP reductase activity
OPI30_RS13315	COG0517	IMP dehydrogenase activity
OPI30_RS13325	COG0366	Alpha amylase catalytic
OPI30_RS13325	COG1874	Beta-galactosidase
OPI30_RS13335	COG1570	exodeoxyribonuclease VII activity
OPI30_RS13360	COG2154	pterin-4-alpha-carbinolamine dehydratase
OPI30_RS13370	COG3768	UPF0283 membrane protein
OPI30_RS13375	COG3106	COG3106 Predicted ATPase
OPI30_RS13390	COG1842	Phage shock protein A
OPI30_RS13395	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OPI30_RS13410	COG4171	peptide transport system, permease
OPI30_RS13420	COG4172	Belongs to the ABC transporter superfamily
OPI30_RS13430	COG1609	Transcriptional regulator
OPI30_RS13435	COG1263	PTS System
OPI30_RS13435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OPI30_RS13440	COG2723	6-phospho-beta-galactosidase activity
OPI30_RS13445	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OPI30_RS13450	COG1286	toxin biosynthetic process
OPI30_RS13455	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OPI30_RS13460	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OPI30_RS13465	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OPI30_RS13470	COG0531	amino acid
OPI30_RS13470	COG1674	ftsk spoiiie
OPI30_RS13485	COG0492	ferredoxin-NADP+ reductase activity
OPI30_RS13490	COG3706	GGDEF domain
OPI30_RS13495	COG3134	Outer membrane lipoprotein
OPI30_RS13500	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OPI30_RS13505	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OPI30_RS13510	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OPI30_RS13515	COG0542	response to heat
OPI30_RS13520	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OPI30_RS13525	COG1278	Cold shock
OPI30_RS13530	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OPI30_RS13545	COG1944	ATP diphosphatase activity
OPI30_RS13550	COG2116	formate transmembrane transporter activity
OPI30_RS13555	COG1882	Formate acetyltransferase
OPI30_RS13560	COG4584	PFAM Integrase catalytic
OPI30_RS13565	COG1484	DNA-dependent DNA replication
OPI30_RS13570	COG2983	Belongs to the UPF0260 family
OPI30_RS13590	COG5433	transposase activity
OPI30_RS13595	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OPI30_RS13600	COG0045	succinate-CoA ligase (ADP-forming) activity
OPI30_RS13605	COG0508	dehydrogenase complex catalyzes the overall conversion of
OPI30_RS13610	COG0567	Dehydrogenase, E1 component
OPI30_RS13625	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OPI30_RS13630	COG2009	succinate dehydrogenase
OPI30_RS13650	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OPI30_RS13655	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OPI30_RS13655	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OPI30_RS13660	COG3385	transposase activity
OPI30_RS13670	COG3069	C4-dicarboxylate transmembrane transporter activity
OPI30_RS13685	COG1451	nucleotide metabolic process
OPI30_RS13700	COG0254	rRNA binding
OPI30_RS13705	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OPI30_RS13715	COG1172	Belongs to the binding-protein-dependent transport system permease family
OPI30_RS13720	COG1129	ABC transporter
OPI30_RS13725	COG1879	ABC-type sugar transport system periplasmic component
OPI30_RS13730	COG1069	ribulokinase activity
OPI30_RS13740	COG2160	L-arabinose isomerase activity
OPI30_RS13750	COG0436	Aminotransferase
OPI30_RS13755	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OPI30_RS13770	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OPI30_RS13770	COG0392	lysyltransferase activity
OPI30_RS13775	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OPI30_RS13785	COG0469	pyruvate kinase activity
OPI30_RS13795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OPI30_RS13795	COG1263	PTS System
OPI30_RS13800	COG1874	Beta-galactosidase
OPI30_RS13805	COG3867	Arabinogalactan endo-beta-1,4-galactanase
OPI30_RS13810	COG3833	ABC-type maltose transport systems, permease component
OPI30_RS13815	COG1175	transmembrane transport
OPI30_RS13820	COG2182	Extracellular solute-binding protein
OPI30_RS13845	COG4580	involved in the transport of maltose and maltodextrins
OPI30_RS13850	COG1609	Transcriptional regulator
OPI30_RS13855	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OPI30_RS13860	COG1085	galactose-1-phosphate uridylyltransferase
OPI30_RS13865	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OPI30_RS13870	COG3385	transposase activity
OPI30_RS13880	COG2801	Transposase and inactivated derivatives
OPI30_RS13885	COG0582	viral genome integration into host DNA
OPI30_RS13890	COG2925	Exonuclease
OPI30_RS13900	COG3345	alpha-galactosidase
OPI30_RS13905	COG1380	Effector of murein hydrolase LrgA
OPI30_RS13910	COG1346	cytolysis
OPI30_RS13915	COG0295	cytidine deaminase activity
OPI30_RS13920	COG1022	Amp-dependent synthetase and ligase
OPI30_RS13935	COG0861	Integral membrane protein TerC family
OPI30_RS13940	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OPI30_RS13945	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OPI30_RS13950	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OPI30_RS13990	COG4771	TonB-dependent receptor
OPI30_RS13995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPI30_RS14000	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OPI30_RS14005	COG1120	ATPase activity
OPI30_RS14020	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OPI30_RS14030	COG1028	Short-chain dehydrogenase reductase Sdr
OPI30_RS14035	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OPI30_RS14040	COG3433	isochorismatase activity
OPI30_RS14040	COG1535	isochorismatase
OPI30_RS14045	COG1021	2,3-dihydroxybenzoate-AMP ligase
OPI30_RS14070	COG5001	Diguanylate cyclase
OPI30_RS14070	COG3300	MHYT domain
OPI30_RS14085	COG0840	transmembrane signaling receptor activity
OPI30_RS14090	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPI30_RS14095	COG3788	relative of glutathione S-transferase, MAPEG superfamily
OPI30_RS14100	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OPI30_RS14105	COG0563	adenylate kinase activity
OPI30_RS14110	COG0326	Molecular chaperone. Has ATPase activity
OPI30_RS14115	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OPI30_RS14120	COG3039	Transposase
OPI30_RS14125	COG3158	transport of potassium into the cell
OPI30_RS14130	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
OPI30_RS14135	COG0298	carbon dioxide binding
OPI30_RS14150	COG0375	protein maturation
OPI30_RS14165	COG3842	ATPase activity
OPI30_RS14170	COG0444	Belongs to the ABC transporter superfamily
OPI30_RS14175	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPI30_RS14180	COG0601	transmembrane transport
OPI30_RS14190	COG1773	rubredoxin
OPI30_RS14195	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
OPI30_RS14200	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
OPI30_RS14205	COG5557	Pfam Polysulphide reductase, NrfD
OPI30_RS14210	COG0437	4 iron, 4 sulfur cluster binding
OPI30_RS14215	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
OPI30_RS14220	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPI30_RS14250	COG3039	Transposase
OPI30_RS14260	COG1484	DNA-dependent DNA replication
OPI30_RS14265	COG4584	PFAM Integrase catalytic
OPI30_RS14320	COG2003	Belongs to the UPF0758 family
OPI30_RS14350	COG3586	endonuclease activity
OPI30_RS14365	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OPI30_RS14385	COG0659	secondary active sulfate transmembrane transporter activity
OPI30_RS14410	COG2308	Evidence 4 Homologs of previously reported genes of
OPI30_RS14445	COG0672	)-iron permease
OPI30_RS14470	COG2814	Major facilitator Superfamily
OPI30_RS14490	COG1136	(ABC) transporter
OPI30_RS14495	COG0577	efflux transmembrane transporter activity
OPI30_RS14510	COG3385	transposase activity
OPI30_RS14545	COG1139	Iron-sulfur cluster binding protein
OPI30_RS14550	COG0247	lactate metabolic process
OPI30_RS14555	COG1620	l-lactate permease
OPI30_RS14560	COG0583	DNA-binding transcription factor activity
OPI30_RS14585	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OPI30_RS14590	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OPI30_RS14590	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OPI30_RS14595	COG0527	aspartate kinase activity
OPI30_RS14605	COG1368	sulfuric ester hydrolase activity
OPI30_RS14610	COG0393	Putative heavy-metal-binding
OPI30_RS14615	COG1252	NADH dehydrogenase
OPI30_RS14620	COG3150	esterase
OPI30_RS14625	COG1164	Oligoendopeptidase f
OPI30_RS14630	COG1164	Oligoendopeptidase f
OPI30_RS14635	COG2354	Protein conserved in bacteria
OPI30_RS14655	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OPI30_RS14660	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OPI30_RS14695	COG0537	adenosine 5'-monophosphoramidase activity
OPI30_RS14710	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OPI30_RS14730	COG1301	dicarboxylic acid transport
OPI30_RS14740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OPI30_RS14745	COG0861	Integral membrane protein TerC family
OPI30_RS14755	COG0444	Belongs to the ABC transporter superfamily
OPI30_RS14775	COG0601	transmembrane transport
OPI30_RS14785	COG2095	MarC family integral membrane protein
OPI30_RS14790	COG1012	belongs to the aldehyde dehydrogenase family
OPI30_RS14790	COG1454	alcohol dehydrogenase
OPI30_RS14800	COG3275	phosphorelay sensor kinase activity
OPI30_RS14805	COG3279	Response regulator of the LytR AlgR family
OPI30_RS14810	COG1966	Carbon starvation protein
OPI30_RS14815	COG3264	Mechanosensitive ion channel
OPI30_RS14815	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OPI30_RS14825	COG1566	PFAM secretion protein HlyD family protein
OPI30_RS14830	COG1061	Type III restriction enzyme res subunit
OPI30_RS14835	COG2027	D-alanyl-D-alanine carboxypeptidase
OPI30_RS14840	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OPI30_RS14850	COG0436	Aminotransferase
OPI30_RS14895	COG0697	spore germination
OPI30_RS14905	COG0675	Transposase, IS605 OrfB family
OPI30_RS14910	COG4657	Part of a membrane complex involved in electron transport
OPI30_RS14915	COG2878	Part of a membrane complex involved in electron transport
OPI30_RS14925	COG4658	electron transport chain
OPI30_RS14930	COG4659	FMN binding
OPI30_RS14935	COG4660	Part of a membrane complex involved in electron transport
OPI30_RS14940	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OPI30_RS14945	COG0346	lactoylglutathione lyase activity
OPI30_RS14975	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OPI30_RS14985	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OPI30_RS14990	COG1086	Polysaccharide biosynthesis protein
OPI30_RS14995	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OPI30_RS15000	COG1083	cytidylyl-transferase
OPI30_RS15060	COG3385	transposase activity
OPI30_RS15080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OPI30_RS15080	COG0301	tRNA thio-modification
OPI30_RS15090	COG4953	penicillin-binding protein 1C
OPI30_RS15095	COG2373	Large extracellular alpha-helical protein
OPI30_RS15100	COG0628	permease
OPI30_RS15105	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPI30_RS15115	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OPI30_RS15125	COG4160	amino acid transport
OPI30_RS15135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS15145	COG2431	L-lysine efflux transmembrane transporter activity
OPI30_RS15150	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OPI30_RS15155	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS15180	COG1393	Belongs to the ArsC family
OPI30_RS15190	COG4783	chaperone-mediated protein folding
OPI30_RS15195	COG0425	Belongs to the sulfur carrier protein TusA family
OPI30_RS15210	COG0596	Alpha beta hydrolase
OPI30_RS15220	COG3842	ATPase activity
OPI30_RS15225	COG3833	ABC-type maltose transport systems, permease component
OPI30_RS15230	COG1175	transmembrane transport
OPI30_RS15245	COG3081	Nucleoid-associated protein
OPI30_RS15250	COG3082	Protein of unknown function (DUF1414)
OPI30_RS15255	COG3083	sulfuric ester hydrolase activity
OPI30_RS15260	COG4771	TonB-dependent receptor
OPI30_RS15265	COG1770	oligopeptidase
OPI30_RS15285	COG4574	serine-type endopeptidase inhibitor activity
OPI30_RS15295	COG3085	chromosome segregation
OPI30_RS15305	COG1605	Chorismate mutase
OPI30_RS15305	COG0287	Prephenate dehydrogenase
OPI30_RS15310	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OPI30_RS15315	COG0584	glycerophosphoryl diester phosphodiesterase
OPI30_RS15325	COG1349	DNA-binding transcription factor activity
OPI30_RS15330	COG2271	Major facilitator Superfamily
OPI30_RS15335	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OPI30_RS15340	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OPI30_RS15345	COG0583	DNA-binding transcription factor activity
OPI30_RS15360	COG3039	Transposase
OPI30_RS15380	COG0656	L-ascorbic acid biosynthetic process
OPI30_RS15385	COG2814	Major facilitator Superfamily
OPI30_RS15395	COG1294	oxidase, subunit
OPI30_RS15400	COG1271	oxidase subunit
OPI30_RS15405	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPI30_RS15415	COG2979	Protein of unknown function (DUF533)
OPI30_RS15435	COG0583	DNA-binding transcription factor activity
OPI30_RS15445	COG2807	transmembrane transport
OPI30_RS15450	COG1187	pseudouridine synthase activity
OPI30_RS15455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OPI30_RS15470	COG3039	Transposase
OPI30_RS15510	COG1166	arginine decarboxylase activity
OPI30_RS15515	COG2195	Cleaves the N-terminal amino acid of tripeptides
OPI30_RS15530	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OPI30_RS15545	COG0583	DNA-binding transcription factor activity
OPI30_RS15555	COG2759	Belongs to the formate--tetrahydrofolate ligase family
OPI30_RS15560	COG0840	transmembrane signaling receptor activity
OPI30_RS15570	COG0840	transmembrane signaling receptor activity
OPI30_RS15575	COG0302	gtp cyclohydrolase
OPI30_RS15585	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OPI30_RS15595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OPI30_RS15610	COG0314	molybdopterin synthase activity
OPI30_RS15615	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OPI30_RS15620	COG0315	cyclic pyranopterin monophosphate synthase activity
OPI30_RS15625	COG0521	Mo-molybdopterin cofactor biosynthetic process
OPI30_RS15630	COG3005	denitrification pathway
OPI30_RS15640	COG0348	domain, Protein
OPI30_RS15645	COG0437	4 iron, 4 sulfur cluster binding
OPI30_RS15650	COG0243	molybdopterin cofactor binding
OPI30_RS15660	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
OPI30_RS15660	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OPI30_RS15665	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OPI30_RS15670	COG3850	Histidine kinase
OPI30_RS15675	COG2197	response regulator
OPI30_RS15690	COG3335	DDE superfamily endonuclease
OPI30_RS15710	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OPI30_RS15720	COG0121	glutamine amidotransferase
OPI30_RS15725	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OPI30_RS15730	COG1960	acyl-CoA dehydrogenase activity
OPI30_RS15735	COG3437	response regulator, receiver
OPI30_RS15735	COG0784	Response regulator, receiver
OPI30_RS15745	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OPI30_RS15750	COG0328	RNA-DNA hybrid ribonuclease activity
OPI30_RS15755	COG2226	methyltransferase
OPI30_RS15760	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OPI30_RS15770	COG0741	lytic transglycosylase activity
OPI30_RS15770	COG1388	LysM domain
OPI30_RS15785	COG1607	acyl-coa hydrolase
OPI30_RS15800	COG0741	lytic transglycosylase activity
OPI30_RS15810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OPI30_RS15830	COG2911	Protein conserved in bacteria
OPI30_RS15835	COG0729	surface antigen
OPI30_RS15845	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OPI30_RS15855	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OPI30_RS15860	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OPI30_RS15865	COG4134	Bacterial extracellular solute-binding protein
OPI30_RS15880	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OPI30_RS15885	COG2951	lytic endotransglycosylase activity
OPI30_RS15890	COG1846	Transcriptional regulator
OPI30_RS15900	COG0033	Phosphoglucomutase
OPI30_RS15905	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
OPI30_RS15910	COG0596	Alpha beta hydrolase
OPI30_RS15925	COG0716	FMN binding
OPI30_RS15935	COG0735	belongs to the Fur family
OPI30_RS15940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPI30_RS15960	COG1263	PTS System
OPI30_RS15960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OPI30_RS15960	COG2190	(PTS) system
OPI30_RS15965	COG0363	glucosamine-6-phosphate deaminase activity
OPI30_RS15970	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OPI30_RS15975	COG1940	carbohydrate kinase activity
OPI30_RS15975	COG1846	Transcriptional regulator
OPI30_RS15985	COG2194	sulfuric ester hydrolase activity
OPI30_RS15990	COG0217	transcriptional regulatory protein
OPI30_RS15995	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OPI30_RS16000	COG1801	Protein of unknown function DUF72
OPI30_RS16005	COG4106	trans-aconitate 2-methyltransferase activity
OPI30_RS16010	COG0500	methyltransferase
OPI30_RS16030	COG0583	DNA-binding transcription factor activity
OPI30_RS16035	COG0791	NLP P60 protein
OPI30_RS16050	COG1309	transcriptional regulator
OPI30_RS16060	COG1454	alcohol dehydrogenase
OPI30_RS16095	COG0534	Mate efflux family protein
OPI30_RS16105	COG2841	Protein conserved in bacteria
OPI30_RS16110	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OPI30_RS16110	COG0674	pyruvate-flavodoxin oxidoreductase activity
OPI30_RS16110	COG1013	pyruvate-flavodoxin oxidoreductase activity
OPI30_RS16110	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OPI30_RS16120	COG3217	Mosc domain protein beta barrel domain protein
OPI30_RS16120	COG0633	Ferredoxin
OPI30_RS16120	COG0633	Ferredoxin
OPI30_RS16120	COG3217	Mosc domain protein beta barrel domain protein
OPI30_RS16125	COG0501	Belongs to the peptidase M48B family
OPI30_RS16130	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OPI30_RS16135	COG1073	alpha beta
OPI30_RS16135	COG2226	methyltransferase
OPI30_RS16140	COG0156	8-amino-7-oxononanoate synthase activity
OPI30_RS16145	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OPI30_RS16150	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OPI30_RS16165	COG0017	Asparaginyl-tRNA synthetase
OPI30_RS16170	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OPI30_RS16185	COG3069	C4-dicarboxylate transmembrane transporter activity
OPI30_RS16200	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OPI30_RS16215	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OPI30_RS16220	COG1393	Belongs to the ArsC family
OPI30_RS16225	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OPI30_RS16230	COG1876	peptidase activity
OPI30_RS16240	COG3263	regulation of cellular component size
OPI30_RS16250	COG1280	lysine exporter protein (LysE YggA)
OPI30_RS16275	COG1957	nucleoside hydrolase
OPI30_RS16280	COG0564	pseudouridine synthase activity
OPI30_RS16290	COG1454	alcohol dehydrogenase
OPI30_RS16295	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OPI30_RS16300	COG0702	epimerase
OPI30_RS16305	COG2914	Belongs to the UPF0125 (RnfH) family
OPI30_RS16310	COG2867	negative regulation of translational initiation
OPI30_RS16315	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OPI30_RS16325	COG0582	viral genome integration into host DNA
OPI30_RS16335	COG5642	Protein of unknown function (DUF2384)
OPI30_RS16435	COG2916	Histone family protein nucleoid-structuring protein H-NS
OPI30_RS16465	COG3311	Transcriptional regulator
OPI30_RS16505	COG0246	Mannitol dehydrogenase
OPI30_RS16510	COG2721	sulfolactate sulfo-lyase activity
OPI30_RS16520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPI30_RS16525	COG0800	Aldolase
OPI30_RS16540	COG3153	acetyltransferase
OPI30_RS16570	COG0259	pyridoxamine-phosphate oxidase activity
OPI30_RS16585	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OPI30_RS16585	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OPI30_RS16590	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OPI30_RS16605	COG0457	Tetratricopeptide repeat
OPI30_RS16615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OPI30_RS16620	COG1138	Cytochrome C-type biogenesis protein
OPI30_RS16625	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OPI30_RS16630	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OPI30_RS16635	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OPI30_RS16640	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OPI30_RS16655	COG0835	chemotaxis
OPI30_RS16665	COG1192	Involved in chromosome partitioning
OPI30_RS16670	COG1360	Flagellar Motor Protein
OPI30_RS16675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OPI30_RS16685	COG0643	Histidine kinase
OPI30_RS16685	COG2198	Histidine kinase
OPI30_RS16685	COG0784	Response regulator, receiver
OPI30_RS16690	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
OPI30_RS16715	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
OPI30_RS16725	COG1684	flagellar biosynthetic protein fliR
OPI30_RS16780	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OPI30_RS16790	COG1677	Flagellar hook-basal body complex protein FliE
OPI30_RS16800	COG1393	Belongs to the ArsC family
OPI30_RS16805	COG0798	PFAM Bile acid sodium symporter
OPI30_RS16810	COG0640	Transcriptional regulator
OPI30_RS16820	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OPI30_RS16845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPI30_RS16850	COG0444	Belongs to the ABC transporter superfamily
OPI30_RS16855	COG4608	Belongs to the ABC transporter superfamily
OPI30_RS16865	COG2971	BadF BadG BcrA BcrD
OPI30_RS16875	COG0840	transmembrane signaling receptor activity
OPI30_RS16895	COG3724	N-succinylarginine dihydrolase activity
OPI30_RS16900	COG0616	signal peptide processing
OPI30_RS16905	COG1028	Short-chain dehydrogenase reductase Sdr
OPI30_RS16910	COG0583	DNA-binding transcription factor activity
OPI30_RS16920	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OPI30_RS16930	COG0583	DNA-binding transcription factor activity
OPI30_RS16935	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OPI30_RS16940	COG1881	PFAM PEBP family protein
OPI30_RS16950	COG3408	Glycogen debranching enzyme
OPI30_RS16950	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
OPI30_RS16955	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPI30_RS16960	COG0739	heme binding
OPI30_RS16965	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OPI30_RS16980	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OPI30_RS16990	COG3091	SprT-like family
OPI30_RS17000	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OPI30_RS17005	COG0189	ligase activity
OPI30_RS17015	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OPI30_RS17035	COG1115	amino acid carrier protein
OPI30_RS17040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OPI30_RS17055	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OPI30_RS17070	COG3385	transposase activity
OPI30_RS17090	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OPI30_RS17095	COG2912	Transglutaminase-like superfamily
OPI30_RS17105	COG2890	protein-(glutamine-N5) methyltransferase activity
OPI30_RS17110	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OPI30_RS17115	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OPI30_RS17120	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OPI30_RS17125	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OPI30_RS17135	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OPI30_RS17140	COG0193	aminoacyl-tRNA hydrolase activity
OPI30_RS17145	COG0012	GTP binding
OPI30_RS17195	COG1196	nuclear chromosome segregation
OPI30_RS17200	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
OPI30_RS17225	COG1136	(ABC) transporter
OPI30_RS17240	COG1309	transcriptional regulator
OPI30_RS17300	COG0625	glutathione transferase activity
OPI30_RS17305	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OPI30_RS17315	COG0583	DNA-binding transcription factor activity
OPI30_RS17325	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OPI30_RS17355	COG3041	Addiction module toxin RelE StbE family
OPI30_RS17360	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OPI30_RS17395	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OPI30_RS17445	COG3328	transposase activity
OPI30_RS17455	COG4584	PFAM Integrase catalytic
OPI30_RS17460	COG1484	DNA-dependent DNA replication
OPI30_RS17510	COG0471	metal ion transport
OPI30_RS17510	COG0490	domain, Protein
OPI30_RS17535	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OPI30_RS17550	COG1012	belongs to the aldehyde dehydrogenase family
OPI30_RS17560	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OPI30_RS17575	COG0180	Tryptophanyl-tRNA synthetase
OPI30_RS17580	COG0546	phosphoglycolate phosphatase activity
OPI30_RS17585	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OPI30_RS17590	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OPI30_RS17600	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OPI30_RS17605	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OPI30_RS17635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OPI30_RS17640	COG0583	DNA-binding transcription factor activity
OPI30_RS17655	COG0583	DNA-binding transcription factor activity
OPI30_RS17665	COG0739	heme binding
OPI30_RS17675	COG1511	domain protein
OPI30_RS17675	COG3264	Mechanosensitive ion channel
OPI30_RS17680	COG0584	glycerophosphoryl diester phosphodiesterase
OPI30_RS17690	COG1053	succinate dehydrogenase
OPI30_RS17695	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OPI30_RS17700	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OPI30_RS17705	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OPI30_RS17720	COG3214	Protein conserved in bacteria
OPI30_RS17745	COG0300	oxidoreductase activity
OPI30_RS17760	COG0642	Histidine kinase
OPI30_RS17765	COG4067	protein conserved in archaea
OPI30_RS17765	COG0189	ligase activity
OPI30_RS17770	COG0516	GMP reductase activity
OPI30_RS17780	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OPI30_RS17785	COG2011	ABC-type metal ion transport system permease component
OPI30_RS17790	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OPI30_RS17795	COG1464	Belongs to the NlpA lipoprotein family
OPI30_RS17810	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPI30_RS17820	COG2199	diguanylate cyclase activity
OPI30_RS17835	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OPI30_RS17850	COG1335	isochorismatase
OPI30_RS17855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OPI30_RS17860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OPI30_RS17865	COG1702	phosphate starvation-inducible protein PhoH
OPI30_RS17870	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OPI30_RS17875	COG4535	Mg2 and Co2 transporter CorC
OPI30_RS17880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OPI30_RS17885	COG2888	peptidyl-tyrosine sulfation
OPI30_RS17890	COG0495	leucyl-tRNA aminoacylation
OPI30_RS17905	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OPI30_RS17910	COG0799	negative regulation of ribosome biogenesis
OPI30_RS17915	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OPI30_RS17920	COG0768	penicillin binding
OPI30_RS17925	COG0772	Belongs to the SEDS family
OPI30_RS17930	COG2951	lytic endotransglycosylase activity
OPI30_RS17935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OPI30_RS17940	COG1686	Belongs to the peptidase S11 family
OPI30_RS17945	COG2921	Belongs to the UPF0250 family
OPI30_RS17950	COG0321	lipoyl(octanoyl) transferase activity
OPI30_RS17955	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OPI30_RS17965	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OPI30_RS17995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
OPI30_RS18010	COG4974	Belongs to the 'phage' integrase family
OPI30_RS18020	COG0312	modulator of DNA gyrase
OPI30_RS18025	COG0312	modulator of DNA gyrase
OPI30_RS18045	COG0826	peptidase U32
OPI30_RS18050	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OPI30_RS18055	COG1422	Protein of unknown function (DUF1090)
OPI30_RS18060	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OPI30_RS18065	COG2211	Major facilitator Superfamily
OPI30_RS18070	COG1185	polyribonucleotide nucleotidyltransferase activity
OPI30_RS18075	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OPI30_RS18080	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OPI30_RS18085	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OPI30_RS18090	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OPI30_RS18095	COG0195	Participates in both transcription termination and antitermination
OPI30_RS18100	COG0779	Required for maturation of 30S ribosomal subunits
OPI30_RS18115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OPI30_RS18120	COG0149	triose-phosphate isomerase activity
OPI30_RS18125	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OPI30_RS18130	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OPI30_RS18140	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OPI30_RS18145	COG1534	Rna-binding protein
OPI30_RS18160	COG1360	Flagellar Motor Protein
OPI30_RS18165	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OPI30_RS18170	COG1722	exodeoxyribonuclease VII activity
OPI30_RS18175	COG0142	geranyltranstransferase activity
OPI30_RS18180	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OPI30_RS18185	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OPI30_RS18190	COG0601	transmembrane transport
OPI30_RS18200	COG4172	Belongs to the ABC transporter superfamily
OPI30_RS18205	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OPI30_RS18210	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OPI30_RS18215	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OPI30_RS18220	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OPI30_RS18235	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OPI30_RS18235	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OPI30_RS18240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OPI30_RS18250	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OPI30_RS18260	COG3381	protein complex oligomerization
OPI30_RS18275	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OPI30_RS18280	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OPI30_RS18285	COG0511	ligase activity, forming carbon-carbon bonds
OPI30_RS18290	COG0439	Biotin carboxylase
OPI30_RS18295	COG3924	membrane
OPI30_RS18300	COG4145	pantothenate transmembrane transporter activity
OPI30_RS18305	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OPI30_RS18305	COG1263	PTS System
OPI30_RS18305	COG2190	(PTS) system
OPI30_RS18310	COG0583	DNA-binding transcription factor activity
OPI30_RS18320	COG2264	protein methyltransferase activity
OPI30_RS18325	COG0110	maltose O-acetyltransferase activity
OPI30_RS18335	COG0778	Nitroreductase
OPI30_RS18340	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPI30_RS18340	COG1902	pentaerythritol trinitrate reductase activity
OPI30_RS18345	COG0616	signal peptide processing
OPI30_RS18365	COG3139	Protein of unknown function (DUF1315)
OPI30_RS18370	COG0252	asparaginase activity
OPI30_RS18375	COG0786	glutamate:sodium symporter activity
OPI30_RS18390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OPI30_RS18395	COG0384	phenazine biosynthesis protein PhzF
OPI30_RS18400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OPI30_RS18405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPI30_RS18410	COG0175	sulfate reduction
OPI30_RS18415	COG3385	transposase activity
OPI30_RS18420	COG2113	Glycine betaine
OPI30_RS18425	COG4176	ABC-type proline glycine betaine transport system permease component
OPI30_RS18430	COG4175	Glycine betaine
OPI30_RS18445	COG2966	Psort location CytoplasmicMembrane, score
OPI30_RS18455	COG0521	Mo-molybdopterin cofactor biosynthetic process
OPI30_RS18475	COG2313	pseudouridylate synthase activity
OPI30_RS18480	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OPI30_RS18485	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPI30_RS18485	COG2146	nitrite reductase [NAD(P)H] activity
OPI30_RS18490	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPI30_RS18490	COG2146	nitrite reductase [NAD(P)H] activity
OPI30_RS18495	COG1116	anion transmembrane transporter activity
OPI30_RS18500	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OPI30_RS18505	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OPI30_RS18505	COG1116	anion transmembrane transporter activity
OPI30_RS18515	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OPI30_RS18515	COG1648	precorrin-2 dehydrogenase activity
OPI30_RS18520	COG0243	molybdopterin cofactor binding
OPI30_RS18550	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OPI30_RS18565	COG1073	alpha beta
OPI30_RS18570	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OPI30_RS18575	COG2195	Cleaves the N-terminal amino acid of tripeptides
OPI30_RS18580	COG4608	Belongs to the ABC transporter superfamily
OPI30_RS18585	COG0444	Belongs to the ABC transporter superfamily
OPI30_RS18595	COG4239	(ABC) transporter, permease
OPI30_RS18600	COG4174	ABC transporter (Permease)
OPI30_RS18605	COG4206	TonB-dependent receptor
OPI30_RS18615	COG0811	peptide transport
OPI30_RS18620	COG0811	peptide transport
OPI30_RS18625	COG0848	biopolymer transport protein
OPI30_RS18675	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPI30_RS18680	COG0840	transmembrane signaling receptor activity
OPI30_RS18690	COG1278	Cold shock
OPI30_RS18730	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OPI30_RS18735	COG1162	GTPase activity
OPI30_RS18740	COG0688	phosphatidylethanolamine metabolic process
OPI30_RS18745	COG4628	conserved protein (DUF2132)
OPI30_RS18770	COG3300	MHYT domain
OPI30_RS18770	COG5001	Diguanylate cyclase
OPI30_RS18775	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
OPI30_RS18805	COG1132	(ABC) transporter
OPI30_RS18815	COG2897	thiosulfate sulfurtransferase activity
OPI30_RS18820	COG2066	Belongs to the glutaminase family
OPI30_RS18825	COG3171	Protein conserved in bacteria
OPI30_RS18830	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OPI30_RS18835	COG2234	aminopeptidase activity
OPI30_RS18835	COG4935	Belongs to the peptidase S8 family
OPI30_RS18840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OPI30_RS18845	COG2200	EAL domain
OPI30_RS18850	COG1090	epimerase
OPI30_RS18855	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OPI30_RS18860	COG4181	ATPase activity
OPI30_RS18865	COG2755	lipolytic protein G-D-S-L family
OPI30_RS18870	COG0784	Response regulator, receiver
OPI30_RS18870	COG0835	chemotaxis
OPI30_RS18880	COG0675	Transposase, IS605 OrfB family
OPI30_RS18890	COG5433	transposase activity
OPI30_RS18900	COG0516	GMP reductase activity
OPI30_RS18900	COG0517	IMP dehydrogenase activity
OPI30_RS18905	COG0488	(ABC) transporter
OPI30_RS18915	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OPI30_RS18960	COG3039	Transposase
OPI30_RS18975	COG0789	Transcriptional regulator
OPI30_RS18990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OPI30_RS19000	COG0668	transmembrane transport
OPI30_RS19010	COG2731	YhcH YjgK YiaL family protein
OPI30_RS19020	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OPI30_RS19025	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OPI30_RS19035	COG1484	DNA-dependent DNA replication
OPI30_RS19040	COG4584	PFAM Integrase catalytic
OPI30_RS19050	COG0583	DNA-binding transcription factor activity
OPI30_RS19055	COG0477	Major facilitator Superfamily
OPI30_RS19080	COG2985	domain, Protein
OPI30_RS19080	COG0569	domain protein
OPI30_RS19085	COG1272	protein, Hemolysin III
OPI30_RS19090	COG0076	glutamate decarboxylase activity
OPI30_RS19095	COG2917	probably involved in intracellular septation
OPI30_RS19100	COG2350	Protein conserved in bacteria
OPI30_RS19110	COG1555	photosystem II stabilization
OPI30_RS19115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OPI30_RS19120	COG3385	transposase activity
OPI30_RS19125	COG3104	oligopeptide transport
OPI30_RS19130	COG0745	RESPONSE REGULATOR receiver
OPI30_RS19165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS19180	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OPI30_RS19215	COG1484	DNA-dependent DNA replication
OPI30_RS19220	COG4584	PFAM Integrase catalytic
OPI30_RS19225	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OPI30_RS19230	COG3385	transposase activity
OPI30_RS19265	COG1280	lysine exporter protein (LysE YggA)
OPI30_RS19290	COG0316	Belongs to the HesB IscA family
OPI30_RS19305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OPI30_RS19330	COG0583	DNA-binding transcription factor activity
OPI30_RS19335	COG2076	Multidrug Resistance protein
OPI30_RS19345	COG0346	lactoylglutathione lyase activity
OPI30_RS19350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OPI30_RS19355	COG1643	Atp-dependent helicase
OPI30_RS19365	COG1489	DNA binding
OPI30_RS19370	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OPI30_RS19375	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OPI30_RS19385	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OPI30_RS19390	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OPI30_RS19395	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OPI30_RS19405	COG0842	Transport permease protein
OPI30_RS19410	COG1131	(ABC) transporter
OPI30_RS19425	COG0163	prenyltransferase activity
OPI30_RS19430	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OPI30_RS19435	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OPI30_RS19460	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
OPI30_RS19475	COG1136	(ABC) transporter
OPI30_RS19495	COG0840	transmembrane signaling receptor activity
OPI30_RS19570	COG0529	Catalyzes the synthesis of activated sulfate
OPI30_RS19575	COG0471	metal ion transport
OPI30_RS19575	COG3273	potassium ion transport
OPI30_RS19580	COG2895	sulfate adenylyltransferase (ATP) activity
OPI30_RS19585	COG0175	sulfate reduction
OPI30_RS19590	COG1648	precorrin-2 dehydrogenase activity
OPI30_RS19590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OPI30_RS19595	COG0330	HflC and HflK could
OPI30_RS19600	COG1585	Membrane protein implicated in regulation of membrane protease activity
OPI30_RS19610	COG0673	inositol 2-dehydrogenase activity
OPI30_RS19620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OPI30_RS19625	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OPI30_RS19650	COG0138	bifunctional purine biosynthesis protein purh
OPI30_RS19685	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OPI30_RS19690	COG0358	DNA primase activity
OPI30_RS19695	COG1610	YqeY-like protein
OPI30_RS19700	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OPI30_RS19705	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OPI30_RS19715	COG1388	LysM domain
OPI30_RS19715	COG4942	peptidase
OPI30_RS19720	COG1238	metal cluster binding
OPI30_RS19725	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OPI30_RS19730	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OPI30_RS19735	COG0585	pseudouridine synthase activity
OPI30_RS19745	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OPI30_RS19750	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OPI30_RS19755	COG0148	phosphopyruvate hydratase activity
OPI30_RS19760	COG0504	CTP synthase activity
OPI30_RS19765	COG3956	TIGRFAM MazG family protein
OPI30_RS19770	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OPI30_RS19775	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPI30_RS19785	COG4807	Protein conserved in bacteria
OPI30_RS19790	COG3023	N-Acetylmuramoyl-L-alanine amidase
OPI30_RS19795	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OPI30_RS19800	COG1381	Involved in DNA repair and RecF pathway recombination
OPI30_RS19810	COG0571	ribonuclease III activity
OPI30_RS19815	COG0681	Belongs to the peptidase S26 family
OPI30_RS19820	COG0481	GTPase activity
OPI30_RS19835	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
OPI30_RS19840	COG1595	DNA-templated transcription, initiation
OPI30_RS19845	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OPI30_RS19855	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OPI30_RS19860	COG0354	folic acid binding
OPI30_RS19865	COG0583	DNA-binding transcription factor activity
OPI30_RS19895	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OPI30_RS19910	COG0126	phosphoglycerate kinase activity
OPI30_RS19915	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OPI30_RS19920	COG1940	carbohydrate kinase activity
OPI30_RS19925	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OPI30_RS19930	COG2816	NAD+ diphosphatase activity
OPI30_RS19935	COG4991	sh3 domain protein
OPI30_RS19940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OPI30_RS19955	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OPI30_RS19960	COG1028	Short-chain dehydrogenase reductase Sdr
OPI30_RS19975	COG1505	serine-type exopeptidase activity
OPI30_RS19980	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OPI30_RS19985	COG0765	amino acid transport
OPI30_RS19995	COG1126	abc transporter atp-binding protein
OPI30_RS20000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OPI30_RS20005	COG3174	membrane
OPI30_RS20010	COG0110	maltose O-acetyltransferase activity
OPI30_RS20040	COG1942	4-Oxalocrotonate Tautomerase
OPI30_RS20050	COG0583	DNA-binding transcription factor activity
OPI30_RS20055	COG0165	Argininosuccinate lyase
OPI30_RS20060	COG0137	argininosuccinate synthase activity
OPI30_RS20070	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OPI30_RS20075	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OPI30_RS20085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OPI30_RS20090	COG5001	Diguanylate cyclase
OPI30_RS20090	COG5002	protein histidine kinase activity
OPI30_RS20090	COG3447	MASE1 domain protein
OPI30_RS20095	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OPI30_RS20130	COG0583	DNA-binding transcription factor activity
OPI30_RS20135	COG1380	Effector of murein hydrolase LrgA
OPI30_RS20140	COG1346	cytolysis
OPI30_RS20145	COG0527	aspartate kinase activity
OPI30_RS20145	COG0460	homoserine dehydrogenase
OPI30_RS20150	COG0626	cystathionine gamma-synthase activity
OPI30_RS20165	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OPI30_RS20170	COG0814	amino acid
OPI30_RS20175	COG1218	3'(2'),5'-bisphosphate nucleotidase
OPI30_RS20180	COG0494	nUDIX hydrolase
OPI30_RS20185	COG1011	Hydrolase
OPI30_RS20190	COG1902	pentaerythritol trinitrate reductase activity
OPI30_RS20200	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OPI30_RS20215	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OPI30_RS20225	COG3156	type II secretion system protein K
OPI30_RS20235	COG4795	General secretion pathway protein
OPI30_RS20240	COG2165	general secretion pathway protein
OPI30_RS20250	COG2165	general secretion pathway protein
OPI30_RS20255	COG1459	type II secretion system
OPI30_RS20260	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OPI30_RS20270	COG3031	protein transport across the cell outer membrane
OPI30_RS20280	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OPI30_RS20285	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OPI30_RS20300	COG0456	acetyltransferase
OPI30_RS20305	COG3133	Outer membrane lipoprotein
OPI30_RS20310	COG3025	triphosphatase activity
OPI30_RS20315	COG1392	Phosphate transport regulator
OPI30_RS20320	COG0306	phosphate transporter
OPI30_RS20325	COG0617	tRNA 3'-terminal CCA addition
OPI30_RS20330	COG3267	Type II secretory pathway component ExeA
OPI30_RS20330	COG3409	Peptidoglycan-binding domain 1 protein
OPI30_RS20340	COG1194	a g-specific adenine glycosylase
OPI30_RS20345	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OPI30_RS20360	COG3240	lipase activity
OPI30_RS20370	COG3009	Protein conserved in bacteria
OPI30_RS20375	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OPI30_RS20375	COG3008	intermembrane lipid transfer
OPI30_RS20380	COG2995	paraquat-inducible protein a
OPI30_RS20390	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OPI30_RS20395	COG2203	Gaf domain
OPI30_RS20395	COG3706	GGDEF domain
OPI30_RS20395	COG4251	negative regulation of phosphorylation
OPI30_RS20395	COG5001	Diguanylate cyclase
OPI30_RS20400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OPI30_RS20405	COG2813	Specifically methylates the guanine in position
OPI30_RS20415	COG0297	glycogen (starch) synthase activity
OPI30_RS20455	COG1757	Na H antiporter
OPI30_RS20470	COG3842	ATPase activity
OPI30_RS20475	COG1176	ABC-type spermidine putrescine transport system, permease component I
OPI30_RS20480	COG1177	transmembrane transport
OPI30_RS20485	COG1012	belongs to the aldehyde dehydrogenase family
OPI30_RS20490	COG0109	protoheme IX farnesyltransferase activity
OPI30_RS20520	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OPI30_RS20530	COG1565	acr, cog1565
OPI30_RS20530	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OPI30_RS20535	COG1444	tRNA N-acetyltransferase activity
OPI30_RS20555	COG1803	Methylglyoxal synthase
OPI30_RS20570	COG0252	asparaginase activity
OPI30_RS20590	COG1263	PTS System
OPI30_RS20590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OPI30_RS20595	COG0366	Alpha amylase catalytic
OPI30_RS20600	COG0110	maltose O-acetyltransferase activity
OPI30_RS20605	COG1522	sequence-specific DNA binding
OPI30_RS20635	COG3068	Protein conserved in bacteria
OPI30_RS20645	COG0739	heme binding
OPI30_RS20665	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
OPI30_RS20670	COG1121	(ABC) transporter
OPI30_RS20675	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OPI30_RS20680	COG0583	DNA-binding transcription factor activity
OPI30_RS20685	COG0697	spore germination
OPI30_RS20690	COG1573	uracil-dna glycosylase
OPI30_RS20695	COG2962	Rard protein
OPI30_RS20700	COG2827	Endonuclease containing a URI domain
OPI30_RS20715	COG1842	Phage shock protein A
OPI30_RS20720	COG0204	Acyl-transferase
OPI30_RS20740	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OPI30_RS20750	COG0484	heat shock protein binding
OPI30_RS20790	COG3039	Transposase
OPI30_RS20795	COG2801	Transposase and inactivated derivatives
OPI30_RS20815	COG1566	PFAM secretion protein HlyD family protein
OPI30_RS20830	COG1051	belongs to the nudix hydrolase family
OPI30_RS20835	COG3150	esterase
OPI30_RS20845	COG3151	Protein conserved in bacteria
OPI30_RS20850	COG0494	nUDIX hydrolase
OPI30_RS20855	COG1538	Outer membrane efflux protein
OPI30_RS20860	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OPI30_RS20860	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OPI30_RS20865	COG1560	Kdo2-lipid A biosynthetic process
OPI30_RS20880	COG2771	luxR family
OPI30_RS20895	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
OPI30_RS20900	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OPI30_RS20900	COG2213	PTS system mannitol-specific
OPI30_RS20905	COG0246	Mannitol dehydrogenase
OPI30_RS20910	COG3722	fumarate hydratase activity
OPI30_RS20915	COG3263	regulation of cellular component size
OPI30_RS20935	COG1671	Belongs to the UPF0178 family
OPI30_RS20950	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OPI30_RS20955	COG0513	Belongs to the DEAD box helicase family
OPI30_RS20975	COG1575	Belongs to the MenA family. Type 1 subfamily
OPI30_RS20980	COG1169	isochorismate synthase
OPI30_RS20985	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OPI30_RS20990	COG0596	Alpha beta hydrolase
OPI30_RS20995	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OPI30_RS21005	COG0318	PFAM AMP-dependent synthetase and ligase
OPI30_RS21010	COG3291	Pkd domain containing protein
OPI30_RS21015	COG2949	membrane
OPI30_RS21020	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OPI30_RS21030	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OPI30_RS21060	COG2873	o-acetylhomoserine
OPI30_RS21070	COG1979	alcohol dehydrogenase
OPI30_RS21085	COG4221	oxidoreductase activity
OPI30_RS21105	COG1285	pathogenesis
OPI30_RS21120	COG1368	sulfuric ester hydrolase activity
OPI30_RS21125	COG1522	sequence-specific DNA binding
OPI30_RS21135	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OPI30_RS21140	COG1418	mRNA catabolic process
OPI30_RS21145	COG1058	Belongs to the CinA family
OPI30_RS21145	COG1546	Belongs to the CinA family
OPI30_RS21150	COG1988	membrane-bound metal-dependent
OPI30_RS21160	COG0561	phosphatase activity
OPI30_RS21165	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OPI30_RS21175	COG1011	Hydrolase
OPI30_RS21190	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OPI30_RS21195	COG0019	diaminopimelate decarboxylase activity
OPI30_RS21205	COG1965	Belongs to the frataxin family
OPI30_RS21210	COG0400	carboxylic ester hydrolase activity
OPI30_RS21215	COG3072	Adenylate cyclase
OPI30_RS21220	COG0181	hydroxymethylbilane synthase activity
OPI30_RS21230	COG2959	enzyme of heme biosynthesis
OPI30_RS21235	COG3071	HemY protein
OPI30_RS21250	COG0312	modulator of DNA gyrase
OPI30_RS21255	COG3028	Belongs to the UPF0307 family
OPI30_RS21270	COG2926	Belongs to the UPF0265 family
OPI30_RS21305	COG1396	sequence-specific DNA binding
OPI30_RS21310	COG3135	benzoate transporter
OPI30_RS21340	COG3047	cAMP biosynthetic process
OPI30_RS21355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OPI30_RS21360	COG2197	response regulator
OPI30_RS21370	COG4974	Belongs to the 'phage' integrase family
OPI30_RS21400	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OPI30_RS21410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OPI30_RS21415	COG3385	transposase activity
OPI30_RS21450	COG1484	DNA-dependent DNA replication
OPI30_RS21455	COG4584	PFAM Integrase catalytic
OPI30_RS21470	COG3385	transposase activity
OPI30_RS21475	COG5499	transcription regulator containing HTH domain
OPI30_RS21495	COG1196	nuclear chromosome segregation
OPI30_RS21510	COG4584	PFAM Integrase catalytic
OPI30_RS21515	COG1484	DNA-dependent DNA replication
OPI30_RS21610	COG1278	Cold shock
OPI30_RS21640	COG3706	GGDEF domain
OPI30_RS21645	COG0347	Belongs to the P(II) protein family
OPI30_RS21650	COG0004	ammonium transporteR
OPI30_RS21670	COG3385	transposase activity
OPI30_RS21680	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OPI30_RS21685	COG1074	ATP-dependent DNA helicase activity
OPI30_RS21690	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OPI30_RS21700	COG3385	transposase activity
OPI30_RS21710	COG1741	Belongs to the pirin family
OPI30_RS21720	COG0583	DNA-binding transcription factor activity
OPI30_RS21745	COG1175	transmembrane transport
OPI30_RS21755	COG3842	ATPase activity
OPI30_RS21785	COG0456	acetyltransferase
OPI30_RS21790	COG0753	catalase activity
OPI30_RS21810	COG0494	nUDIX hydrolase
OPI30_RS21815	COG0628	permease
OPI30_RS21840	COG1461	Dihydroxyacetone kinase
OPI30_RS21845	COG2376	Dihydroxyacetone kinase
OPI30_RS21850	COG2252	PERMEase
OPI30_RS21885	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OPI30_RS21890	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OPI30_RS21895	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OPI30_RS21900	COG0049	tRNA binding
OPI30_RS21905	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OPI30_RS21910	COG2168	tRNA wobble position uridine thiolation
OPI30_RS21920	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OPI30_RS21925	COG0251	oxidation-reduction process
OPI30_RS21930	COG2964	Protein conserved in bacteria
OPI30_RS21935	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OPI30_RS21940	COG0085	RNA polymerase activity
OPI30_RS21945	COG0222	ribosome binding
OPI30_RS21950	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OPI30_RS21955	COG0081	regulation of translation
OPI30_RS21960	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OPI30_RS21965	COG0250	Participates in transcription elongation, termination and antitermination
OPI30_RS21980	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OPI30_RS22005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OPI30_RS22010	COG0569	domain protein
OPI30_RS22015	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OPI30_RS22020	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OPI30_RS22025	COG3005	denitrification pathway
OPI30_RS22030	COG0243	molybdopterin cofactor binding
OPI30_RS22065	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OPI30_RS22075	COG2204	response regulator
OPI30_RS22085	COG2205	protein histidine kinase activity
OPI30_RS22105	COG0516	GMP reductase activity
OPI30_RS22105	COG0517	IMP dehydrogenase activity
OPI30_RS22115	COG1522	sequence-specific DNA binding
OPI30_RS22120	COG2502	aspartate--ammonia ligase
OPI30_RS22135	COG0583	DNA-binding transcription factor activity
OPI30_RS22140	COG0542	response to heat
OPI30_RS22150	COG0564	pseudouridine synthase activity
OPI30_RS22155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OPI30_RS22160	COG3681	Belongs to the UPF0597 family
OPI30_RS22165	COG2964	Protein conserved in bacteria
OPI30_RS22170	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OPI30_RS22175	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OPI30_RS22180	COG1979	alcohol dehydrogenase
OPI30_RS22185	COG2207	Transcriptional regulator
OPI30_RS22190	COG3040	lipid binding
OPI30_RS22210	COG0583	DNA-binding transcription factor activity
OPI30_RS22230	COG0540	Belongs to the ATCase OTCase family
OPI30_RS22235	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OPI30_RS22240	COG1438	arginine binding
OPI30_RS22245	COG1288	antiporter activity
OPI30_RS22250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OPI30_RS22290	COG3250	beta-galactosidase activity
OPI30_RS22295	COG1609	Transcriptional regulator
OPI30_RS22300	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OPI30_RS22310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OPI30_RS22315	COG2017	converts alpha-aldose to the beta-anomer
OPI30_RS22320	COG0667	Aldo Keto reductase
OPI30_RS22325	COG1968	undecaprenyl-diphosphatase activity
OPI30_RS22330	COG3806	Anti-sigma factor
OPI30_RS22335	COG1595	DNA-templated transcription, initiation
OPI30_RS22355	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OPI30_RS22360	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OPI30_RS22380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OPI30_RS22385	COG1131	(ABC) transporter
OPI30_RS22390	COG0842	Transport permease protein
OPI30_RS22395	COG0842	Transport permease protein
OPI30_RS22400	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OPI30_RS22410	COG2116	formate transmembrane transporter activity
OPI30_RS22415	COG1648	precorrin-2 dehydrogenase activity
OPI30_RS22415	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OPI30_RS22420	COG2239	Acts as a magnesium transporter
OPI30_RS22425	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OPI30_RS22430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OPI30_RS22440	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OPI30_RS22450	COG0514	ATP-dependent DNA helicase (RecQ)
OPI30_RS22455	COG2050	protein possibly involved in aromatic compounds catabolism
OPI30_RS22470	COG2258	MOSC domain
OPI30_RS22475	COG1177	transmembrane transport
OPI30_RS22480	COG1176	ABC-type spermidine putrescine transport system, permease component I
OPI30_RS22485	COG3842	ATPase activity
OPI30_RS22505	COG0174	glutamine synthetase
OPI30_RS22525	COG3045	CreA protein
OPI30_RS22530	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OPI30_RS22535	COG0443	Heat shock 70 kDa protein
OPI30_RS22550	COG0366	Alpha amylase catalytic
OPI30_RS22570	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OPI30_RS22575	COG0745	RESPONSE REGULATOR receiver
OPI30_RS22580	COG2205	protein histidine kinase activity
OPI30_RS22590	COG0281	malic enzyme
OPI30_RS22595	COG0702	epimerase
OPI30_RS22600	COG0254	rRNA binding
OPI30_RS22605	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OPI30_RS22640	COG0129	dihydroxy-acid dehydratase activity
OPI30_RS22650	COG3978	acetolactate synthase activity
OPI30_RS22660	COG0606	chelatase, subunit chli
OPI30_RS22665	COG0204	Acyl-transferase
OPI30_RS22670	COG0204	Acyl-transferase
OPI30_RS22675	COG1683	Conserved Protein
OPI30_RS22685	COG1335	isochorismatase
OPI30_RS22695	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
OPI30_RS22700	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
OPI30_RS22705	COG3639	organic phosphonate transmembrane transporter activity
OPI30_RS22710	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OPI30_RS22715	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OPI30_RS22725	COG3084	Protein conserved in bacteria
OPI30_RS22730	COG3706	GGDEF domain
OPI30_RS22730	COG5001	Diguanylate cyclase
OPI30_RS22730	COG4251	negative regulation of phosphorylation
OPI30_RS22730	COG2203	Gaf domain
OPI30_RS22745	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OPI30_RS22750	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OPI30_RS22755	COG1561	YicC-like family, N-terminal region
OPI30_RS22765	COG1519	Transferase
OPI30_RS22770	COG0859	PFAM glycosyl transferase family 9
OPI30_RS22775	COG0463	Glycosyl transferase, family 2
OPI30_RS22780	COG0859	PFAM glycosyl transferase family 9
OPI30_RS22785	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OPI30_RS22790	COG2990	Protein conserved in bacteria
OPI30_RS22795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OPI30_RS22805	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OPI30_RS22810	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OPI30_RS22815	COG2003	Belongs to the UPF0758 family
OPI30_RS22820	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OPI30_RS22825	COG0756	dUTP diphosphatase activity
OPI30_RS22830	COG1309	transcriptional regulator
OPI30_RS22850	COG0668	transmembrane transport
OPI30_RS22860	COG0166	Belongs to the GPI family
OPI30_RS22865	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OPI30_RS22870	COG0583	DNA-binding transcription factor activity
OPI30_RS22880	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OPI30_RS22880	COG1042	CoA-binding domain protein
OPI30_RS22880	COG0045	succinate-CoA ligase (ADP-forming) activity
OPI30_RS22905	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
OPI30_RS22910	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OPI30_RS22915	COG1739	Uncharacterized protein family UPF0029
OPI30_RS22920	COG0006	proline dipeptidase activity
OPI30_RS22925	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OPI30_RS22930	COG1250	3-hydroxyacyl-CoA dehydrogenase
OPI30_RS22930	COG1024	Enoyl-CoA hydratase
OPI30_RS22935	COG0183	Belongs to the thiolase family
OPI30_RS22975	COG0425	Belongs to the sulfur carrier protein TusA family
OPI30_RS22980	COG0251	oxidation-reduction process
OPI30_RS22995	COG2885	chlorophyll binding
OPI30_RS23005	COG1335	isochorismatase
OPI30_RS23010	COG2818	Glycosylase
OPI30_RS23015	COG0752	glycyl-tRNA synthetase alpha subunit
OPI30_RS23020	COG0751	glycine-tRNA ligase activity
OPI30_RS23030	COG5001	Diguanylate cyclase
OPI30_RS23030	COG4251	negative regulation of phosphorylation
OPI30_RS23030	COG2203	Gaf domain
OPI30_RS23030	COG3706	GGDEF domain
OPI30_RS23045	COG0814	amino acid
OPI30_RS23050	COG0814	amino acid
OPI30_RS23055	COG3033	Beta-eliminating lyase
OPI30_RS23065	COG0348	domain, Protein
OPI30_RS23075	COG0446	pyridine nucleotide-disulphide oxidoreductase
OPI30_RS23080	COG0426	domain, Protein
OPI30_RS23080	COG1773	rubredoxin
OPI30_RS23085	COG3604	Transcriptional regulator
OPI30_RS23130	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OPI30_RS23160	COG2960	long-chain fatty acid transporting porin activity
OPI30_RS23170	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OPI30_RS23185	COG3118	belongs to the thioredoxin family
OPI30_RS23190	COG0513	Belongs to the DEAD box helicase family
OPI30_RS23195	COG0248	Ppx GppA phosphatase
OPI30_RS23210	COG0742	ribosomal rna small subunit methyltransferase
OPI30_RS23230	COG0084	hydrolase, TatD family'
OPI30_RS23235	COG0805	protein transport
OPI30_RS23240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OPI30_RS23245	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OPI30_RS23250	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OPI30_RS23255	COG3165	ubiquinone biosynthetic process from chorismate
OPI30_RS23265	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OPI30_RS23270	COG0402	S-adenosylhomocysteine deaminase activity
OPI30_RS23305	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
OPI30_RS23310	COG0848	biopolymer transport protein
OPI30_RS23315	COG0811	peptide transport
OPI30_RS23320	COG0811	peptide transport
OPI30_RS23330	COG2771	luxR family
OPI30_RS23335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OPI30_RS23340	COG1349	DNA-binding transcription factor activity
OPI30_RS23345	COG0745	RESPONSE REGULATOR receiver
OPI30_RS23350	COG2205	protein histidine kinase activity
OPI30_RS23360	COG4452	Inner membrane protein CreD
OPI30_RS23365	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OPI30_RS23370	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OPI30_RS23375	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OPI30_RS23380	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OPI30_RS23385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OPI30_RS23390	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OPI30_RS23395	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OPI30_RS23405	COG0356	it plays a direct role in the translocation of protons across the membrane
OPI30_RS23415	COG1475	DNA binding
OPI30_RS23420	COG1192	Involved in chromosome partitioning
OPI30_RS23425	COG0357	Ribosomal RNA small subunit methyltransferase G
OPI30_RS23430	COG0445	tRNA wobble uridine modification
OPI30_RS23435	COG0716	FMN binding
OPI30_RS23440	COG4774	siderophore transport
OPI30_RS23445	COG4615	Cyclic peptide transporter
OPI30_RS23450	COG1120	ATPase activity
OPI30_RS23455	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OPI30_RS23465	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OPI30_RS23470	COG0706	membrane insertase activity
OPI30_RS23475	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OPI30_RS23480	COG0594	ribonuclease P activity
OPI30_RS23485	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OPI30_RS23490	COG1126	abc transporter atp-binding protein
OPI30_RS23505	COG3385	transposase activity
OPI30_RS23545	COG3385	transposase activity
OPI30_RS23550	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OPI30_RS23555	COG0592	DNA-directed DNA polymerase activity
OPI30_RS23565	COG0187	DNA topoisomerase II activity
OPI30_RS23570	COG2207	Transcriptional regulator
OPI30_RS23575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OPI30_RS23580	COG0071	Belongs to the small heat shock protein (HSP20) family
OPI30_RS23585	COG0071	Belongs to the small heat shock protein (HSP20) family
OPI30_RS23590	COG3977	Valine--pyruvate aminotransferase
OPI30_RS23605	COG2814	Major facilitator Superfamily
OPI30_RS23610	COG0745	RESPONSE REGULATOR receiver
OPI30_RS23615	COG2205	protein histidine kinase activity
OPI30_RS23635	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family