locus-tag	class	description
OCX50_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
OCX50_RS00010	COG0592	DNA-directed DNA polymerase activity
OCX50_RS00020	COG0187	DNA topoisomerase II activity
OCX50_RS00025	COG2207	Transcriptional regulator
OCX50_RS00030	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
OCX50_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
OCX50_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
OCX50_RS00045	COG3977	Valine--pyruvate aminotransferase
OCX50_RS00060	COG2814	Major facilitator Superfamily
OCX50_RS00065	COG0745	RESPONSE REGULATOR receiver
OCX50_RS00070	COG2205	protein histidine kinase activity
OCX50_RS00090	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCX50_RS00095	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS00095	COG4191	Histidine kinase
OCX50_RS00100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCX50_RS00105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS00110	COG1309	transcriptional regulator
OCX50_RS00140	COG0561	phosphatase activity
OCX50_RS00145	COG2267	carboxylic ester hydrolase activity
OCX50_RS00150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCX50_RS00155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OCX50_RS00160	COG1758	RNA polymerase activity
OCX50_RS00170	COG0859	PFAM glycosyl transferase family 9
OCX50_RS00175	COG3642	lipopolysaccharide core region biosynthetic process
OCX50_RS00215	COG0589	response to stress
OCX50_RS00225	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCX50_RS00230	COG3706	GGDEF domain
OCX50_RS00235	COG1528	Iron-storage protein
OCX50_RS00240	COG2081	HI0933 family
OCX50_RS00245	COG2223	nitrite transmembrane transporter activity
OCX50_RS00250	COG1280	lysine exporter protein (LysE YggA)
OCX50_RS00265	COG3188	usher protein
OCX50_RS00290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS00290	COG2205	protein histidine kinase activity
OCX50_RS00300	COG3275	phosphorelay sensor kinase activity
OCX50_RS00305	COG3279	Response regulator of the LytR AlgR family
OCX50_RS00310	COG2223	nitrite transmembrane transporter activity
OCX50_RS00315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
OCX50_RS00320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
OCX50_RS00335	COG0583	DNA-binding transcription factor activity
OCX50_RS00390	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
OCX50_RS00395	COG2166	iron-sulfur cluster assembly
OCX50_RS00400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
OCX50_RS00420	COG1063	alcohol dehydrogenase
OCX50_RS00435	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OCX50_RS00440	COG0438	transferase activity, transferring glycosyl groups
OCX50_RS00480	COG1580	Controls the rotational direction of flagella during chemotaxis
OCX50_RS00485	COG3161	chorismate lyase activity
OCX50_RS00490	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
OCX50_RS00495	COG2937	Belongs to the GPAT DAPAT family
OCX50_RS00500	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OCX50_RS00515	COG0534	Mate efflux family protein
OCX50_RS00520	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
OCX50_RS00525	COG2205	protein histidine kinase activity
OCX50_RS00530	COG0745	RESPONSE REGULATOR receiver
OCX50_RS00540	COG1045	serine acetyltransferase
OCX50_RS00550	COG3074	FtsZ-dependent cytokinesis
OCX50_RS00555	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
OCX50_RS00560	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCX50_RS00560	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCX50_RS00565	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
OCX50_RS00600	COG1609	Transcriptional regulator
OCX50_RS00605	COG3250	beta-galactosidase activity
OCX50_RS00610	COG2731	YhcH YjgK YiaL family protein
OCX50_RS00615	COG0531	amino acid
OCX50_RS00620	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCX50_RS00625	COG0531	amino acid
OCX50_RS00630	COG0385	Bile acid
OCX50_RS00635	COG1262	PFAM Formylglycine-generating sulfatase enzyme
OCX50_RS00660	COG0583	DNA-binding transcription factor activity
OCX50_RS00665	COG1079	Belongs to the binding-protein-dependent transport system permease family
OCX50_RS00670	COG4603	Belongs to the binding-protein-dependent transport system permease family
OCX50_RS00675	COG3845	ABC transporter
OCX50_RS00680	COG1744	ABC transporter substrate-binding protein PnrA-like
OCX50_RS00700	COG0210	DNA helicase
OCX50_RS00705	COG3039	Transposase
OCX50_RS00730	COG1943	Transposase
OCX50_RS00735	COG0583	DNA-binding transcription factor activity
OCX50_RS00780	COG1280	lysine exporter protein (LysE YggA)
OCX50_RS00790	COG2962	Rard protein
OCX50_RS00800	COG1012	belongs to the aldehyde dehydrogenase family
OCX50_RS00805	COG1396	sequence-specific DNA binding
OCX50_RS00810	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
OCX50_RS00820	COG0519	Catalyzes the synthesis of GMP from XMP
OCX50_RS00820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCX50_RS00830	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCX50_RS00850	COG1322	Protein conserved in bacteria
OCX50_RS00855	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCX50_RS00860	COG0569	domain protein
OCX50_RS00865	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCX50_RS00865	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCX50_RS00870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
OCX50_RS00875	COG0242	peptide deformylase activity
OCX50_RS00885	COG0758	DNA mediated transformation
OCX50_RS00890	COG2922	Belongs to the Smg family
OCX50_RS00895	COG0551	DNA topoisomerase type I activity
OCX50_RS00900	COG0009	L-threonylcarbamoyladenylate synthase
OCX50_RS00905	COG0408	coproporphyrinogen oxidase activity
OCX50_RS00910	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
OCX50_RS00915	COG0218	Necessary for normal cell division and for the maintenance of normal septation
OCX50_RS00925	COG3078	GTPase activator activity
OCX50_RS00940	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OCX50_RS00950	COG3852	Histidine kinase
OCX50_RS00960	COG0174	glutamine synthetase
OCX50_RS00965	COG1217	gtp-binding protein TYPA
OCX50_RS00970	COG1295	ribonuclease BN
OCX50_RS00975	COG1490	D-aminoacyl-tRNA deacylase activity
OCX50_RS00985	COG0456	acetyltransferase
OCX50_RS00995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
OCX50_RS01000	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OCX50_RS01005	COG2610	gluconate transmembrane transporter activity
OCX50_RS01010	COG3265	gluconokinase activity
OCX50_RS01015	COG0129	dihydroxy-acid dehydratase activity
OCX50_RS01020	COG0800	Aldolase
OCX50_RS01035	COG1609	Transcriptional regulator
OCX50_RS01045	COG4942	peptidase
OCX50_RS01050	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
OCX50_RS01060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCX50_RS01065	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
OCX50_RS01070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
OCX50_RS01075	COG0316	Belongs to the HesB IscA family
OCX50_RS01075	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
OCX50_RS01080	COG1040	competence protein
OCX50_RS01085	COG0596	Alpha beta hydrolase
OCX50_RS01100	COG2183	response to ionizing radiation
OCX50_RS01105	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCX50_RS01115	COG2205	protein histidine kinase activity
OCX50_RS01125	COG0051	transcription antitermination factor activity, RNA binding
OCX50_RS01130	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
OCX50_RS01135	COG0088	Forms part of the polypeptide exit tunnel
OCX50_RS01140	COG0089	rRNA binding
OCX50_RS01145	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
OCX50_RS01150	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
OCX50_RS01155	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
OCX50_RS01160	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
OCX50_RS01165	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
OCX50_RS01170	COG0255	Belongs to the universal ribosomal protein uL29 family
OCX50_RS01175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
OCX50_RS01180	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
OCX50_RS01185	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
OCX50_RS01190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
OCX50_RS01195	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
OCX50_RS01200	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
OCX50_RS01205	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
OCX50_RS01210	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
OCX50_RS01215	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
OCX50_RS01220	COG1841	ribosomal large subunit assembly
OCX50_RS01225	COG0200	Binds to the 23S rRNA
OCX50_RS01230	COG0201	protein transport
OCX50_RS01235	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OCX50_RS01240	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
OCX50_RS01245	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
OCX50_RS01250	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
OCX50_RS01255	COG0202	RNA polymerase activity
OCX50_RS01260	COG0203	ribosomal protein L17
OCX50_RS01310	COG2249	NAD(P)H dehydrogenase (quinone) activity
OCX50_RS01315	COG0583	DNA-binding transcription factor activity
OCX50_RS01320	COG4221	oxidoreductase activity
OCX50_RS01335	COG1770	oligopeptidase
OCX50_RS01340	COG2358	TRAP transporter, solute receptor (TAXI family
OCX50_RS01355	COG3714	YhhN family
OCX50_RS01370	COG0583	DNA-binding transcription factor activity
OCX50_RS01380	COG1301	dicarboxylic acid transport
OCX50_RS01390	COG2095	MarC family integral membrane protein
OCX50_RS01400	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCX50_RS01410	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OCX50_RS01420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
OCX50_RS01445	COG0742	ribosomal rna small subunit methyltransferase
OCX50_RS01450	COG0552	protein localization to endoplasmic reticulum
OCX50_RS01455	COG2884	Cell division ATP-binding protein ftsE
OCX50_RS01460	COG2177	Part of the ABC transporter FtsEX involved in
OCX50_RS01470	COG0288	reversible hydration of carbon dioxide
OCX50_RS01475	COG2188	Transcriptional regulator
OCX50_RS01480	COG1228	amidohydrolase
OCX50_RS01485	COG0010	Belongs to the arginase family
OCX50_RS01490	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
OCX50_RS01495	COG2986	histidine ammonia-lyase
OCX50_RS01500	COG0387	Pfam Sodium calcium exchanger
OCX50_RS01505	COG2200	EAL domain
OCX50_RS01560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCX50_RS01565	COG1459	type II secretion system
OCX50_RS01580	COG4969	Belongs to the N-Me-Phe pilin family
OCX50_RS01610	COG1077	Cell shape determining protein MreB Mrl
OCX50_RS01615	COG1792	Involved in formation and maintenance of cell shape
OCX50_RS01620	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
OCX50_RS01625	COG0424	maF-like protein
OCX50_RS01630	COG1530	ribonuclease E activity
OCX50_RS01635	COG3164	Protein of unknown function
OCX50_RS01640	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCX50_RS01645	COG0312	modulator of DNA gyrase
OCX50_RS01665	COG1263	PTS System
OCX50_RS01665	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCX50_RS01670	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
OCX50_RS01685	COG0477	Major facilitator Superfamily
OCX50_RS01695	COG2321	neutral zinc metallopeptidase
OCX50_RS01730	COG0189	ligase activity
OCX50_RS01735	COG0642	Histidine kinase
OCX50_RS01740	COG0745	RESPONSE REGULATOR receiver
OCX50_RS01755	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
OCX50_RS01765	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCX50_RS01775	COG2022	thiamine diphosphate biosynthetic process
OCX50_RS01780	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OCX50_RS01795	COG0110	maltose O-acetyltransferase activity
OCX50_RS01810	COG3932	Exopolysaccharide synthesis, ExoD
OCX50_RS01830	COG1733	regulation of RNA biosynthetic process
OCX50_RS01860	COG1494	fructose-1,6-bisphosphatase
OCX50_RS01870	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
OCX50_RS01875	COG5007	Belongs to the BolA IbaG family
OCX50_RS01885	COG2854	intermembrane phospholipid transfer
OCX50_RS01890	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCX50_RS01895	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
OCX50_RS01900	COG1127	ABC transporter
OCX50_RS01905	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
OCX50_RS01905	COG0517	IMP dehydrogenase activity
OCX50_RS01910	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
OCX50_RS01920	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
OCX50_RS01925	COG1137	ATPase activity
OCX50_RS01930	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
OCX50_RS01940	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCX50_RS01945	COG1660	Displays ATPase and GTPase activities
OCX50_RS01950	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCX50_RS01970	COG3964	amidohydrolase
OCX50_RS02000	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OCX50_RS02005	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OCX50_RS02015	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
OCX50_RS02020	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
OCX50_RS02025	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
OCX50_RS02030	COG0723	plastoquinol--plastocyanin reductase activity
OCX50_RS02035	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
OCX50_RS02040	COG2857	Cytochrome c1
OCX50_RS02045	COG0625	glutathione transferase activity
OCX50_RS02050	COG2969	positive regulation of protein catabolic process
OCX50_RS02055	COG2823	Periplasmic or secreted lipoprotein
OCX50_RS02060	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OCX50_RS02065	COG0792	nuclease activity
OCX50_RS02070	COG3107	peptidoglycan biosynthetic process
OCX50_RS02075	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
OCX50_RS02090	COG2001	Belongs to the MraZ family
OCX50_RS02095	COG0275	rRNA processing
OCX50_RS02100	COG3116	cell division
OCX50_RS02105	COG0768	penicillin binding
OCX50_RS02110	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
OCX50_RS02115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
OCX50_RS02120	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCX50_RS02125	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
OCX50_RS02130	COG0772	Belongs to the SEDS family
OCX50_RS02135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
OCX50_RS02140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCX50_RS02145	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
OCX50_RS02150	COG0849	cell division
OCX50_RS02155	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
OCX50_RS02160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
OCX50_RS02170	COG0653	protein targeting
OCX50_RS02180	COG0494	nUDIX hydrolase
OCX50_RS02185	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
OCX50_RS02190	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
OCX50_RS02200	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
OCX50_RS02205	COG1459	type II secretion system
OCX50_RS02210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCX50_RS02235	COG2186	Transcriptional regulator
OCX50_RS02240	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
OCX50_RS02245	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCX50_RS02250	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCX50_RS02260	COG0840	transmembrane signaling receptor activity
OCX50_RS02265	COG0840	transmembrane signaling receptor activity
OCX50_RS02270	COG1752	Esterase of the alpha-beta hydrolase superfamily
OCX50_RS02275	COG1049	propionate catabolic process, 2-methylcitrate cycle
OCX50_RS02280	COG2200	EAL domain
OCX50_RS02290	COG1280	lysine exporter protein (LysE YggA)
OCX50_RS02300	COG0523	cobalamin synthesis protein
OCX50_RS02305	COG0477	Major facilitator Superfamily
OCX50_RS02320	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
OCX50_RS02325	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
OCX50_RS02375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
OCX50_RS02385	COG1546	Belongs to the CinA family
OCX50_RS02390	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
OCX50_RS02395	COG2137	regulation of response to DNA damage stimulus
OCX50_RS02400	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
OCX50_RS02405	COG0527	aspartate kinase activity
OCX50_RS02410	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
OCX50_RS02445	COG1686	Belongs to the peptidase S11 family
OCX50_RS02450	COG0586	Pfam SNARE associated Golgi protein
OCX50_RS02455	COG1253	flavin adenine dinucleotide binding
OCX50_RS02460	COG0525	valine-tRNA ligase activity
OCX50_RS02470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCX50_RS02475	COG0795	lipopolysaccharide-transporting ATPase activity
OCX50_RS02480	COG0795	lipopolysaccharide-transporting ATPase activity
OCX50_RS02530	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
OCX50_RS02630	COG4695	Portal protein
OCX50_RS02775	COG4974	Belongs to the 'phage' integrase family
OCX50_RS02785	COG0004	ammonium transporteR
OCX50_RS02790	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCX50_RS02805	COG2165	general secretion pathway protein
OCX50_RS02810	COG0084	hydrolase, TatD family'
OCX50_RS02815	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCX50_RS02825	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
OCX50_RS02830	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
OCX50_RS02835	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
OCX50_RS02840	COG0813	purine-nucleoside phosphorylase activity
OCX50_RS02845	COG3447	MASE1 domain protein
OCX50_RS02845	COG5001	Diguanylate cyclase
OCX50_RS02845	COG5002	protein histidine kinase activity
OCX50_RS02855	COG0560	Phosphoserine phosphatase
OCX50_RS02870	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
OCX50_RS02880	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
OCX50_RS02885	COG0776	regulation of translation
OCX50_RS02900	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCX50_RS02905	COG0735	belongs to the Fur family
OCX50_RS02925	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
OCX50_RS02930	COG0513	Belongs to the DEAD box helicase family
OCX50_RS02935	COG3022	response to hydroperoxide
OCX50_RS02950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
OCX50_RS02955	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
OCX50_RS02960	COG0762	integral membrane protein
OCX50_RS02965	COG1872	DUF167
OCX50_RS02990	COG3112	Uncharacterised protein family (UPF0231)
OCX50_RS02995	COG3835	regulator
OCX50_RS03000	COG2610	gluconate transmembrane transporter activity
OCX50_RS03005	COG1929	Belongs to the glycerate kinase type-1 family
OCX50_RS03020	COG0583	DNA-binding transcription factor activity
OCX50_RS03025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCX50_RS03040	COG0347	Belongs to the P(II) protein family
OCX50_RS03055	COG3842	ATPase activity
OCX50_RS03060	COG2837	iron assimilation
OCX50_RS03065	COG1438	arginine binding
OCX50_RS03070	COG1126	abc transporter atp-binding protein
OCX50_RS03075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS03080	COG4215	(ABC) transporter
OCX50_RS03085	COG4160	amino acid transport
OCX50_RS03090	COG0039	L-malate dehydrogenase activity
OCX50_RS03095	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
OCX50_RS03100	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCX50_RS03100	COG1017	nitric oxide dioxygenase activity
OCX50_RS03110	COG4536	flavin adenine dinucleotide binding
OCX50_RS03115	COG4137	Cytochrome C assembly protein
OCX50_RS03120	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
OCX50_RS03125	COG0228	four-way junction DNA binding
OCX50_RS03130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
OCX50_RS03135	COG0336	Belongs to the RNA methyltransferase TrmD family
OCX50_RS03140	COG0335	large ribosomal subunit rRNA binding
OCX50_RS03150	COG3066	DNA modification
OCX50_RS03155	COG1051	belongs to the nudix hydrolase family
OCX50_RS03165	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
OCX50_RS03170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
OCX50_RS03175	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OCX50_RS03185	COG0583	DNA-binding transcription factor activity
OCX50_RS03190	COG0640	Transcriptional regulator
OCX50_RS03195	COG0268	Binds directly to 16S ribosomal RNA
OCX50_RS03200	COG0728	peptidoglycan biosynthetic process
OCX50_RS03205	COG0196	riboflavin kinase activity
OCX50_RS03210	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
OCX50_RS03215	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
OCX50_RS03220	COG1047	Peptidyl-prolyl cis-trans
OCX50_RS03225	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
OCX50_RS03255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
OCX50_RS03255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCX50_RS03270	COG1854	S-ribosylhomocysteine lyase activity
OCX50_RS03280	COG0557	exoribonuclease II activity
OCX50_RS03315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
OCX50_RS03325	COG2153	protein acetylation
OCX50_RS03335	COG1914	H( )-stimulated, divalent metal cation uptake system
OCX50_RS03340	COG0360	Binds together with S18 to 16S ribosomal RNA
OCX50_RS03345	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
OCX50_RS03350	COG0359	binds to the 23S rRNA
OCX50_RS03390	COG1238	metal cluster binding
OCX50_RS03395	COG0612	Peptidase, M16
OCX50_RS03400	COG2918	glutathione biosynthetic process
OCX50_RS03405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OCX50_RS03410	COG1027	Aspartate ammonia-lyase
OCX50_RS03415	COG3030	protein affecting phage T7 exclusion by the F plasmid
OCX50_RS03420	COG0534	Mate efflux family protein
OCX50_RS03425	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
OCX50_RS03430	COG0459	protein refolding
OCX50_RS03450	COG0564	pseudouridine synthase activity
OCX50_RS03455	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
OCX50_RS03495	COG1484	DNA-dependent DNA replication
OCX50_RS03500	COG4584	PFAM Integrase catalytic
OCX50_RS03515	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
OCX50_RS03520	COG4208	sulfate ABC transporter
OCX50_RS03525	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
OCX50_RS03530	COG0583	DNA-binding transcription factor activity
OCX50_RS03535	COG3397	chitin binding
OCX50_RS03540	COG0840	transmembrane signaling receptor activity
OCX50_RS03565	COG1328	CTP reductase activity
OCX50_RS03570	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OCX50_RS03585	COG1448	Aminotransferase
OCX50_RS03590	COG2194	sulfuric ester hydrolase activity
OCX50_RS03615	COG1215	transferase activity, transferring glycosyl groups
OCX50_RS03620	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
OCX50_RS03625	COG0457	Tetratricopeptide repeat
OCX50_RS03625	COG3118	belongs to the thioredoxin family
OCX50_RS03660	COG0513	Belongs to the DEAD box helicase family
OCX50_RS03665	COG0840	transmembrane signaling receptor activity
OCX50_RS03675	COG4166	transmembrane transport
OCX50_RS03690	COG1024	Enoyl-CoA hydratase
OCX50_RS03705	COG4221	oxidoreductase activity
OCX50_RS03710	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCX50_RS03715	COG0442	prolyl-tRNA aminoacylation
OCX50_RS03720	COG0840	transmembrane signaling receptor activity
OCX50_RS03725	COG0632	four-way junction helicase activity
OCX50_RS03730	COG2255	four-way junction helicase activity
OCX50_RS03740	COG1271	oxidase subunit
OCX50_RS03745	COG1294	oxidase, subunit
OCX50_RS03750	COG4890	Cyd operon protein YbgT
OCX50_RS03755	COG3790	cyd operon protein YbgE
OCX50_RS03760	COG0824	Thioesterase
OCX50_RS03765	COG0811	peptide transport
OCX50_RS03780	COG0823	Involved in the tonB-independent uptake of proteins
OCX50_RS03785	COG2885	chlorophyll binding
OCX50_RS03790	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
OCX50_RS03865	COG0840	transmembrane signaling receptor activity
OCX50_RS03870	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
OCX50_RS03880	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OCX50_RS03885	COG1640	4-alpha-glucanotransferase
OCX50_RS03890	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
OCX50_RS03920	COG2130	NADP-dependent
OCX50_RS03925	COG1846	Transcriptional regulator
OCX50_RS03955	COG0561	phosphatase activity
OCX50_RS03970	COG0733	neurotransmitter:sodium symporter activity
OCX50_RS03975	COG0733	neurotransmitter:sodium symporter activity
OCX50_RS03990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCX50_RS04010	COG1794	racemase activity, acting on amino acids and derivatives
OCX50_RS04020	COG1022	Amp-dependent synthetase and ligase
OCX50_RS04030	COG0456	acetyltransferase
OCX50_RS04045	COG2425	protein containing a von Willebrand factor type A (vWA) domain
OCX50_RS04050	COG5001	Diguanylate cyclase
OCX50_RS04050	COG5002	protein histidine kinase activity
OCX50_RS04060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
OCX50_RS04070	COG0456	acetyltransferase
OCX50_RS04080	COG0456	acetyltransferase
OCX50_RS04085	COG1902	pentaerythritol trinitrate reductase activity
OCX50_RS04095	COG2852	Protein conserved in bacteria
OCX50_RS04105	COG2957	Belongs to the agmatine deiminase family
OCX50_RS04110	COG0154	amidase activity
OCX50_RS04155	COG2207	Transcriptional regulator
OCX50_RS04155	COG1917	Cupin 2, conserved barrel domain protein
OCX50_RS04165	COG0513	Belongs to the DEAD box helicase family
OCX50_RS04170	COG2203	Gaf domain
OCX50_RS04170	COG2199	diguanylate cyclase activity
OCX50_RS04210	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
OCX50_RS04225	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCX50_RS04235	COG4584	PFAM Integrase catalytic
OCX50_RS04240	COG1484	DNA-dependent DNA replication
OCX50_RS04245	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
OCX50_RS04255	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
OCX50_RS04260	COG1178	ABC-type Fe3 transport system permease component
OCX50_RS04265	COG4143	(ABC) transporter
OCX50_RS04280	COG0066	3-isopropylmalate dehydratase activity
OCX50_RS04285	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
OCX50_RS04290	COG0473	3-isopropylmalate dehydrogenase activity
OCX50_RS04295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OCX50_RS04305	COG0671	phosphoesterase, PA-phosphatase related
OCX50_RS04320	COG0028	Belongs to the TPP enzyme family
OCX50_RS04325	COG0440	acetolactate synthase activity
OCX50_RS04330	COG0857	belongs to the CobB CobQ family
OCX50_RS04330	COG0280	phosphate acetyltransferase
OCX50_RS04335	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
OCX50_RS04345	COG3013	Belongs to the UPF0304 family
OCX50_RS04350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
OCX50_RS04355	COG2716	regulation of RNA biosynthetic process
OCX50_RS04360	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCX50_RS04365	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
OCX50_RS04370	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
OCX50_RS04390	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
OCX50_RS04410	COG2198	Histidine kinase
OCX50_RS04410	COG0784	Response regulator, receiver
OCX50_RS04410	COG5002	protein histidine kinase activity
OCX50_RS04425	COG2205	protein histidine kinase activity
OCX50_RS04425	COG0784	Response regulator, receiver
OCX50_RS04445	COG1464	Belongs to the NlpA lipoprotein family
OCX50_RS04450	COG2011	ABC-type metal ion transport system permease component
OCX50_RS04455	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
OCX50_RS04475	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
OCX50_RS04475	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
OCX50_RS04480	COG0802	atpase or kinase
OCX50_RS04490	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
OCX50_RS04495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
OCX50_RS04500	COG1923	regulation of RNA biosynthetic process
OCX50_RS04505	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
OCX50_RS04510	COG0330	HflC and HflK could
OCX50_RS04515	COG0330	HflC and HflK could
OCX50_RS04520	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
OCX50_RS04525	COG0142	geranyltranstransferase activity
OCX50_RS04530	COG0261	This protein binds to 23S rRNA in the presence of protein L20
OCX50_RS04535	COG0211	Belongs to the bacterial ribosomal protein bL27 family
OCX50_RS04540	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
OCX50_RS04545	COG3314	Sporulation integral membrane protein YlbJ
OCX50_RS04550	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OCX50_RS04555	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
OCX50_RS04565	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OCX50_RS04570	COG2967	ApaG domain
OCX50_RS04575	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
OCX50_RS04580	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
OCX50_RS04590	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
OCX50_RS04595	COG3178	'Phosphotransferase
OCX50_RS04600	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
OCX50_RS04605	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OCX50_RS04610	COG2252	PERMEase
OCX50_RS04620	COG0488	(ABC) transporter
OCX50_RS04625	COG0741	lytic transglycosylase activity
OCX50_RS04630	COG0463	Glycosyl transferase, family 2
OCX50_RS04640	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
OCX50_RS04665	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCX50_RS04675	COG3721	Heme iron utilization protein
OCX50_RS04680	COG0748	coenzyme F420 binding
OCX50_RS04705	COG2814	Major facilitator Superfamily
OCX50_RS04710	COG2202	Pas domain
OCX50_RS04710	COG2205	protein histidine kinase activity
OCX50_RS04720	COG2226	methyltransferase
OCX50_RS04730	COG1765	OsmC-like protein
OCX50_RS04745	COG3954	Phosphoribulokinase
OCX50_RS04750	COG3089	Belongs to the UPF0270 family
OCX50_RS04755	COG2203	Gaf domain
OCX50_RS04755	COG3706	GGDEF domain
OCX50_RS04755	COG4251	negative regulation of phosphorylation
OCX50_RS04755	COG5001	Diguanylate cyclase
OCX50_RS04760	COG0429	hydrolase of the alpha beta-hydrolase fold
OCX50_RS04765	COG0784	Response regulator, receiver
OCX50_RS04765	COG0835	chemotaxis
OCX50_RS04775	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
OCX50_RS04780	COG1047	Peptidyl-prolyl cis-trans
OCX50_RS04785	COG2900	Belongs to the SlyX family
OCX50_RS04795	COG0545	Peptidyl-prolyl cis-trans isomerase
OCX50_RS04800	COG2204	response regulator
OCX50_RS04825	COG5433	transposase activity
OCX50_RS04840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OCX50_RS04845	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OCX50_RS04845	COG0506	proline dehydrogenase activity
OCX50_RS04845	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
OCX50_RS04855	COG0114	fumarate hydratase activity
OCX50_RS04865	COG1566	PFAM secretion protein HlyD family protein
OCX50_RS04910	COG2199	diguanylate cyclase activity
OCX50_RS04910	COG2200	EAL domain
OCX50_RS04910	COG2203	Gaf domain
OCX50_RS04935	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCX50_RS04945	COG1280	lysine exporter protein (LysE YggA)
OCX50_RS04950	COG0826	peptidase U32
OCX50_RS04960	COG3813	Protein conserved in bacteria
OCX50_RS04980	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
OCX50_RS05005	COG0300	oxidoreductase activity
OCX50_RS05025	COG2610	gluconate transmembrane transporter activity
OCX50_RS05030	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
OCX50_RS05035	COG3622	Belongs to the hyi family
OCX50_RS05040	COG0235	Class ii aldolase
OCX50_RS05045	COG3395	kinase activity
OCX50_RS05050	COG2084	Dehydrogenase
OCX50_RS05055	COG1349	DNA-binding transcription factor activity
OCX50_RS05065	COG2133	pyrroloquinoline quinone binding
OCX50_RS05110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCX50_RS05120	COG2916	Histone family protein nucleoid-structuring protein H-NS
OCX50_RS05150	COG3385	transposase activity
OCX50_RS05170	COG1484	DNA-dependent DNA replication
OCX50_RS05175	COG4584	PFAM Integrase catalytic
OCX50_RS05195	COG3039	Transposase
OCX50_RS05220	COG0077	Prephenate dehydratase
OCX50_RS05220	COG1605	Chorismate mutase
OCX50_RS05250	COG3272	Protein of unknown function (DUF1722)
OCX50_RS05255	COG0789	Transcriptional regulator
OCX50_RS05260	COG0415	Belongs to the DNA photolyase family
OCX50_RS05270	COG4221	oxidoreductase activity
OCX50_RS05285	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
OCX50_RS05310	COG0783	Belongs to the Dps family
OCX50_RS05315	COG1151	hydroxylamine reductase activity
OCX50_RS05325	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OCX50_RS05345	COG1447	Phosphotransferase system cellobiose-specific component IIA
OCX50_RS05350	COG2723	6-phospho-beta-galactosidase activity
OCX50_RS05360	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
OCX50_RS05365	COG2273	Hydrolase Family 16
OCX50_RS05365	COG5297	Belongs to the glycosyl hydrolase family 6
OCX50_RS05370	COG1472	Belongs to the glycosyl hydrolase 3 family
OCX50_RS05375	COG0840	transmembrane signaling receptor activity
OCX50_RS05380	COG2182	Extracellular solute-binding protein
OCX50_RS05385	COG1609	Transcriptional regulator
OCX50_RS05410	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCX50_RS05415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS05420	COG0745	RESPONSE REGULATOR receiver
OCX50_RS05425	COG2205	protein histidine kinase activity
OCX50_RS05430	COG0659	secondary active sulfate transmembrane transporter activity
OCX50_RS05445	COG1666	GTP binding
OCX50_RS05455	COG2211	Major facilitator Superfamily
OCX50_RS05465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCX50_RS05475	COG2813	Specifically methylates the guanine in position
OCX50_RS05480	COG0271	Belongs to the BolA IbaG family
OCX50_RS05485	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCX50_RS05490	COG1805	sodium ion transport
OCX50_RS05495	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCX50_RS05500	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCX50_RS05505	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCX50_RS05510	COG2871	sodium ion transport
OCX50_RS05515	COG1477	protein flavinylation
OCX50_RS05530	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OCX50_RS05535	COG0840	transmembrane signaling receptor activity
OCX50_RS05540	COG0583	DNA-binding transcription factor activity
OCX50_RS05555	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
OCX50_RS05565	COG0473	3-isopropylmalate dehydrogenase activity
OCX50_RS05570	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
OCX50_RS05575	COG1611	Belongs to the LOG family
OCX50_RS05590	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCX50_RS05590	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
OCX50_RS05600	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
OCX50_RS05625	COG3098	single-species biofilm formation
OCX50_RS05630	COG0564	pseudouridine synthase activity
OCX50_RS05645	COG4580	involved in the transport of maltose and maltodextrins
OCX50_RS05655	COG1263	PTS System
OCX50_RS05655	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCX50_RS05665	COG2171	N-acyltransferase activity
OCX50_RS05670	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
OCX50_RS05675	COG0024	Methionine aminopeptidase
OCX50_RS05680	COG0052	Belongs to the universal ribosomal protein uS2 family
OCX50_RS05685	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
OCX50_RS05690	COG0528	UMP kinase activity
OCX50_RS05695	COG0233	cytoplasmic translational termination
OCX50_RS05700	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
OCX50_RS05705	COG0575	Belongs to the CDS family
OCX50_RS05710	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
OCX50_RS05715	COG0750	zinc metalloprotease
OCX50_RS05730	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCX50_RS05735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCX50_RS05740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCX50_RS05745	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCX50_RS05750	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
OCX50_RS05755	COG0587	DNA-directed DNA polymerase activity
OCX50_RS05760	COG0825	malonyl-CoA metabolic process
OCX50_RS05775	COG0814	amino acid
OCX50_RS05780	COG0531	amino acid
OCX50_RS05790	COG0488	(ABC) transporter
OCX50_RS05805	COG0037	tRNA processing
OCX50_RS05810	COG3706	GGDEF domain
OCX50_RS05845	COG0366	Alpha amylase catalytic
OCX50_RS05860	COG0463	Glycosyl transferase, family 2
OCX50_RS05875	COG2989	Protein conserved in bacteria
OCX50_RS05880	COG3108	Peptidase M15
OCX50_RS05890	COG2860	membrane
OCX50_RS05900	COG1196	nuclear chromosome segregation
OCX50_RS05905	COG3115	cell septum assembly
OCX50_RS05910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
OCX50_RS05920	COG1328	CTP reductase activity
OCX50_RS05925	COG0602	queuosine metabolic process
OCX50_RS05955	COG1566	PFAM secretion protein HlyD family protein
OCX50_RS05965	COG3290	protein histidine kinase activity
OCX50_RS05980	COG0667	Aldo Keto reductase
OCX50_RS05990	COG0697	spore germination
OCX50_RS06005	COG3284	Transcriptional regulator
OCX50_RS06010	COG3706	GGDEF domain
OCX50_RS06015	COG0346	lactoylglutathione lyase activity
OCX50_RS06020	COG0745	RESPONSE REGULATOR receiver
OCX50_RS06025	COG5002	protein histidine kinase activity
OCX50_RS06035	COG4783	chaperone-mediated protein folding
OCX50_RS06045	COG1940	carbohydrate kinase activity
OCX50_RS06050	COG3142	Participates in the control of copper homeostasis
OCX50_RS06070	COG0545	Peptidyl-prolyl cis-trans isomerase
OCX50_RS06090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS06095	COG4597	amino acid ABC transporter
OCX50_RS06100	COG0765	amino acid transport
OCX50_RS06105	COG1126	abc transporter atp-binding protein
OCX50_RS06115	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
OCX50_RS06120	COG0678	peroxiredoxin activity
OCX50_RS06130	COG0019	diaminopimelate decarboxylase activity
OCX50_RS06135	COG1115	amino acid carrier protein
OCX50_RS06140	COG0095	Lipoate-protein ligase
OCX50_RS06165	COG2207	Transcriptional regulator
OCX50_RS06170	COG0281	malic enzyme
OCX50_RS06205	COG0733	neurotransmitter:sodium symporter activity
OCX50_RS06210	COG1752	Esterase of the alpha-beta hydrolase superfamily
OCX50_RS06215	COG3706	GGDEF domain
OCX50_RS06225	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCX50_RS06230	COG1032	radical SAM domain protein
OCX50_RS06260	COG3385	transposase activity
OCX50_RS06270	COG0673	inositol 2-dehydrogenase activity
OCX50_RS06275	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
OCX50_RS06280	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OCX50_RS06290	COG0741	lytic transglycosylase activity
OCX50_RS06290	COG1196	nuclear chromosome segregation
OCX50_RS06290	COG0739	heme binding
OCX50_RS06315	COG0788	formyltetrahydrofolate deformylase activity
OCX50_RS06320	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCX50_RS06330	COG3118	belongs to the thioredoxin family
OCX50_RS06340	COG0791	NLP P60 protein
OCX50_RS06345	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
OCX50_RS06360	COG1376	ErfK ybiS ycfS ynhG family protein
OCX50_RS06360	COG1388	LysM domain
OCX50_RS06370	COG0784	Response regulator, receiver
OCX50_RS06370	COG2205	protein histidine kinase activity
OCX50_RS06395	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS06395	COG2205	protein histidine kinase activity
OCX50_RS06400	COG3384	dioxygenase
OCX50_RS06410	COG1283	sodium-dependent phosphate transmembrane transporter activity
OCX50_RS06420	COG0531	amino acid
OCX50_RS06425	COG0531	amino acid
OCX50_RS06440	COG1012	belongs to the aldehyde dehydrogenase family
OCX50_RS06445	COG1396	sequence-specific DNA binding
OCX50_RS06445	COG1917	Cupin 2, conserved barrel domain protein
OCX50_RS06450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCX50_RS06485	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
OCX50_RS06485	COG4651	solute:proton antiporter activity
OCX50_RS06490	COG0405	Gamma-glutamyltransferase
OCX50_RS06500	COG2974	May be involved in recombination
OCX50_RS06505	COG1247	-acetyltransferase
OCX50_RS06510	COG0420	3'-5' exonuclease activity
OCX50_RS06525	COG3038	cytochrome b561
OCX50_RS06530	COG2190	(PTS) system
OCX50_RS06540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCX50_RS06545	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
OCX50_RS06550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCX50_RS06565	COG1720	tRNA m6t6A37 methyltransferase activity
OCX50_RS06590	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
OCX50_RS06595	COG4988	ABC transporter
OCX50_RS06610	COG0745	RESPONSE REGULATOR receiver
OCX50_RS06620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OCX50_RS06635	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
OCX50_RS06640	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
OCX50_RS06650	COG0083	homoserine kinase activity
OCX50_RS06655	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCX50_RS06690	COG5433	transposase activity
OCX50_RS06700	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
OCX50_RS06710	COG3220	belongs to the UPF0276 family
OCX50_RS06745	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OCX50_RS06755	COG1289	transmembrane transporter activity
OCX50_RS06760	COG1763	Mo-molybdopterin cofactor biosynthetic process
OCX50_RS06765	COG0746	molybdenum cofactor guanylyltransferase activity
OCX50_RS06770	COG0281	malic enzyme
OCX50_RS06810	COG1196	nuclear chromosome segregation
OCX50_RS06810	COG3264	Mechanosensitive ion channel
OCX50_RS06820	COG2850	peptidyl-arginine hydroxylation
OCX50_RS06825	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
OCX50_RS06830	COG2915	High frequency lysogenization protein hflD homolog
OCX50_RS06835	COG0482	sulfurtransferase activity
OCX50_RS06845	COG1187	pseudouridine synthase activity
OCX50_RS06850	COG0456	acetyltransferase
OCX50_RS06885	COG0538	isocitrate dehydrogenase activity
OCX50_RS06895	COG3048	D-serine ammonia-lyase activity
OCX50_RS06900	COG0583	DNA-binding transcription factor activity
OCX50_RS06905	COG2916	Histone family protein nucleoid-structuring protein H-NS
OCX50_RS06910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCX50_RS06915	COG2375	cellular response to nickel ion
OCX50_RS06920	COG1538	Outer membrane efflux protein
OCX50_RS06925	COG0577	efflux transmembrane transporter activity
OCX50_RS06925	COG1136	(ABC) transporter
OCX50_RS06930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS06940	COG0497	DNA recombination
OCX50_RS06945	COG3706	GGDEF domain
OCX50_RS06950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
OCX50_RS06955	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
OCX50_RS06960	COG0443	Heat shock 70 kDa protein
OCX50_RS06965	COG0484	heat shock protein binding
OCX50_RS06995	COG1285	pathogenesis
OCX50_RS07005	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCX50_RS07015	COG0640	Transcriptional regulator
OCX50_RS07045	COG0095	Lipoate-protein ligase
OCX50_RS07060	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCX50_RS07065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS07080	COG0708	Exodeoxyribonuclease III
OCX50_RS07090	COG0745	RESPONSE REGULATOR receiver
OCX50_RS07105	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
OCX50_RS07120	COG1846	Transcriptional regulator
OCX50_RS07135	COG0675	Transposase, IS605 OrfB family
OCX50_RS07150	COG0583	DNA-binding transcription factor activity
OCX50_RS07155	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OCX50_RS07165	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OCX50_RS07170	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
OCX50_RS07175	COG1845	cytochrome c oxidase, subunit III
OCX50_RS07180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
OCX50_RS07185	COG0109	protoheme IX farnesyltransferase activity
OCX50_RS07190	COG2814	Major facilitator Superfamily
OCX50_RS07195	COG5507	3-demethylubiquinone-9 3-methyltransferase
OCX50_RS07225	COG3550	peptidyl-serine autophosphorylation
OCX50_RS07230	COG1396	sequence-specific DNA binding
OCX50_RS07235	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCX50_RS07250	COG0159	tryptophan synthase activity
OCX50_RS07255	COG0133	tryptophan synthase activity
OCX50_RS07260	COG0135	phosphoribosylanthranilate isomerase activity
OCX50_RS07260	COG0134	indole-3-glycerol-phosphate synthase activity
OCX50_RS07265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OCX50_RS07270	COG0512	Glutamine amidotransferase of anthranilate synthase
OCX50_RS07270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
OCX50_RS07275	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
OCX50_RS07280	COG0613	PHP domain protein
OCX50_RS07285	COG0009	L-threonylcarbamoyladenylate synthase
OCX50_RS07295	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
OCX50_RS07305	COG1946	Acyl-CoA thioesterase
OCX50_RS07320	COG1309	transcriptional regulator
OCX50_RS07325	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS07330	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
OCX50_RS07390	COG1484	DNA-dependent DNA replication
OCX50_RS07395	COG4584	PFAM Integrase catalytic
OCX50_RS07405	COG2003	Belongs to the UPF0758 family
OCX50_RS07420	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCX50_RS07435	COG0583	DNA-binding transcription factor activity
OCX50_RS07460	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
OCX50_RS07470	COG1960	acyl-CoA dehydrogenase activity
OCX50_RS07485	COG0469	pyruvate kinase activity
OCX50_RS07490	COG1737	Transcriptional regulator
OCX50_RS07515	COG1091	dTDP-4-dehydrorhamnose reductase activity
OCX50_RS07590	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
OCX50_RS07595	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
OCX50_RS07615	COG3132	Protein of unknown function, DUF480
OCX50_RS07640	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
OCX50_RS07655	COG1278	Cold shock
OCX50_RS07680	COG0675	Transposase, IS605 OrfB family
OCX50_RS07700	COG0697	spore germination
OCX50_RS07710	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
OCX50_RS07725	COG4166	transmembrane transport
OCX50_RS07730	COG0622	Phosphoesterase
OCX50_RS07745	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
OCX50_RS07750	COG0835	chemotaxis
OCX50_RS07750	COG0784	Response regulator, receiver
OCX50_RS07755	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
OCX50_RS07760	COG1815	bacterial-type flagellum-dependent cell motility
OCX50_RS07790	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
OCX50_RS07795	COG1706	bacterial-type flagellum-dependent cell motility
OCX50_RS07800	COG3951	Flagellar rod assembly protein muramidase FlgJ
OCX50_RS07800	COG1705	Flagellar rod assembly protein muramidase FlgJ
OCX50_RS07815	COG2239	Acts as a magnesium transporter
OCX50_RS07825	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
OCX50_RS07830	COG2716	regulation of RNA biosynthetic process
OCX50_RS07865	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
OCX50_RS07870	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
OCX50_RS07875	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
OCX50_RS07885	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
OCX50_RS07905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
OCX50_RS07920	COG0590	tRNA wobble adenosine to inosine editing
OCX50_RS07925	COG0573	inorganic phosphate transmembrane transporter activity
OCX50_RS07930	COG0581	inorganic phosphate transmembrane transporter activity
OCX50_RS07935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
OCX50_RS07940	COG0704	Plays a role in the regulation of phosphate uptake
OCX50_RS07945	COG1253	flavin adenine dinucleotide binding
OCX50_RS07960	COG0531	amino acid
OCX50_RS07970	COG1126	abc transporter atp-binding protein
OCX50_RS07980	COG0765	amino acid transport
OCX50_RS07985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS07990	COG3706	GGDEF domain
OCX50_RS07995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
OCX50_RS08015	COG1785	Belongs to the alkaline phosphatase family
OCX50_RS08020	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
OCX50_RS08025	COG0477	Major facilitator Superfamily
OCX50_RS08030	COG0123	including yeast histone deacetylase and acetoin utilization protein
OCX50_RS08040	COG1199	ATP-dependent helicase activity
OCX50_RS08045	COG5433	transposase activity
OCX50_RS08070	COG1448	Aminotransferase
OCX50_RS08075	COG0433	COG0433 Predicted ATPase
OCX50_RS08090	COG2333	competence protein COMEC
OCX50_RS08090	COG0658	competence protein
OCX50_RS08095	COG1132	(ABC) transporter
OCX50_RS08100	COG1663	tetraacyldisaccharide 4'-kinase activity
OCX50_RS08105	COG2835	tetraacyldisaccharide 4'-kinase activity
OCX50_RS08110	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
OCX50_RS08115	COG2197	response regulator
OCX50_RS08120	COG0322	excinuclease ABC activity
OCX50_RS08155	COG0604	alcohol dehydrogenase
OCX50_RS08160	COG1309	transcriptional regulator
OCX50_RS08165	COG2261	transglycosylase associated protein
OCX50_RS08170	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
OCX50_RS08180	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
OCX50_RS08185	COG0215	cysteine-tRNA ligase activity
OCX50_RS08210	COG3039	Transposase
OCX50_RS08245	COG3385	transposase activity
OCX50_RS08260	COG2199	diguanylate cyclase activity
OCX50_RS08260	COG2203	Gaf domain
OCX50_RS08295	COG2119	membrane
OCX50_RS08300	COG0023	Translation Initiation Factor
OCX50_RS08310	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
OCX50_RS08335	COG4139	cobalamin transport
OCX50_RS08340	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
OCX50_RS08345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCX50_RS08350	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OCX50_RS08355	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCX50_RS08360	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
OCX50_RS08365	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
OCX50_RS08375	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
OCX50_RS08380	COG0505	Belongs to the CarA family
OCX50_RS08385	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
OCX50_RS08390	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
OCX50_RS08395	COG3706	GGDEF domain
OCX50_RS08425	COG0513	Belongs to the DEAD box helicase family
OCX50_RS08435	COG4104	PAAR repeat-containing protein
OCX50_RS08450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS08455	COG0765	amino acid transport
OCX50_RS08460	COG1126	abc transporter atp-binding protein
OCX50_RS08465	COG0493	'glutamate synthase
OCX50_RS08470	COG0070	glutamate synthase
OCX50_RS08470	COG0069	glutamate synthase activity
OCX50_RS08470	COG0067	glutamate synthase
OCX50_RS08475	COG1242	4 iron, 4 sulfur cluster binding
OCX50_RS08495	COG5433	transposase activity
OCX50_RS08540	COG1113	amino acid transport
OCX50_RS08550	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
OCX50_RS08555	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
OCX50_RS08555	COG0574	Belongs to the PEP-utilizing enzyme family
OCX50_RS08560	COG1119	ATPase activity
OCX50_RS08580	COG1464	Belongs to the NlpA lipoprotein family
OCX50_RS08590	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
OCX50_RS08595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCX50_RS08605	COG0101	tRNA pseudouridine synthase activity
OCX50_RS08610	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
OCX50_RS08615	COG0285	dihydrofolate synthase activity
OCX50_RS08620	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
OCX50_RS08625	COG2920	part of a sulfur-relay system
OCX50_RS08630	COG1289	transmembrane transporter activity
OCX50_RS08635	COG0670	Belongs to the BI1 family
OCX50_RS08655	COG5433	transposase activity
OCX50_RS08675	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
OCX50_RS08685	COG5001	Diguanylate cyclase
OCX50_RS08690	COG0564	pseudouridine synthase activity
OCX50_RS08705	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
OCX50_RS08715	COG0625	glutathione transferase activity
OCX50_RS08730	COG0367	asparagine synthase
OCX50_RS08740	COG0647	UMP catabolic process
OCX50_RS08745	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
OCX50_RS08755	COG1902	pentaerythritol trinitrate reductase activity
OCX50_RS08760	COG1253	flavin adenine dinucleotide binding
OCX50_RS08775	COG0247	lactate metabolic process
OCX50_RS08775	COG0277	FAD linked oxidase domain protein
OCX50_RS08785	COG2050	protein possibly involved in aromatic compounds catabolism
OCX50_RS08800	COG5001	Diguanylate cyclase
OCX50_RS08805	COG0583	DNA-binding transcription factor activity
OCX50_RS08810	COG2814	Major facilitator Superfamily
OCX50_RS08815	COG2056	Na+-H+ antiporter family
OCX50_RS08820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCX50_RS08835	COG0483	inositol monophosphate 1-phosphatase activity
OCX50_RS08845	COG0625	glutathione transferase activity
OCX50_RS08850	COG0625	glutathione transferase activity
OCX50_RS08860	COG0601	transmembrane transport
OCX50_RS08865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCX50_RS08870	COG0444	Belongs to the ABC transporter superfamily
OCX50_RS08875	COG2814	Major facilitator Superfamily
OCX50_RS08900	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCX50_RS08905	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCX50_RS08910	COG0404	The glycine cleavage system catalyzes the degradation of glycine
OCX50_RS08915	COG0509	glycine decarboxylation via glycine cleavage system
OCX50_RS08920	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCX50_RS08920	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
OCX50_RS08945	COG3634	alkyl hydroperoxide reductase activity
OCX50_RS08950	COG0450	alkyl hydroperoxide reductase
OCX50_RS08955	COG0517	IMP dehydrogenase activity
OCX50_RS08960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
OCX50_RS08965	COG0343	queuine tRNA-ribosyltransferase activity
OCX50_RS08970	COG1862	Preprotein translocase
OCX50_RS08975	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCX50_RS08980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCX50_RS08985	COG2897	thiosulfate sulfurtransferase activity
OCX50_RS08995	COG0826	peptidase U32
OCX50_RS09000	COG0826	peptidase U32
OCX50_RS09005	COG3154	lipid carrier protein
OCX50_RS09020	COG1104	cysteine desulfurase activity
OCX50_RS09025	COG0822	iron-sulfur transferase activity
OCX50_RS09035	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
OCX50_RS09040	COG0443	Heat shock 70 kDa protein
OCX50_RS09045	COG0633	Ferredoxin
OCX50_RS09060	COG0105	UTP biosynthetic process
OCX50_RS09065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
OCX50_RS09075	COG1426	Protein conserved in bacteria
OCX50_RS09085	COG0124	histidyl-tRNA synthetase
OCX50_RS09090	COG2976	Protein conserved in bacteria
OCX50_RS09095	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCX50_RS09100	COG1160	GTP binding
OCX50_RS09105	COG1645	bacterial-type flagellum-dependent swarming motility
OCX50_RS09115	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
OCX50_RS09120	COG0047	phosphoribosylformylglycinamidine synthase activity
OCX50_RS09120	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
OCX50_RS09125	COG1007	ATP synthesis coupled electron transport
OCX50_RS09130	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCX50_RS09140	COG0713	ATP synthesis coupled electron transport
OCX50_RS09145	COG0839	Belongs to the complex I subunit 6 family
OCX50_RS09150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCX50_RS09155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
OCX50_RS09160	COG1034	ATP synthesis coupled electron transport
OCX50_RS09175	COG0649	NAD binding
OCX50_RS09175	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCX50_RS09180	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCX50_RS09185	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
OCX50_RS09190	COG1360	Flagellar Motor Protein
OCX50_RS09195	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OCX50_RS09210	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS09240	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
OCX50_RS09250	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
OCX50_RS09260	COG0724	RNA recognition motif
OCX50_RS09265	COG4989	oxidoreductase activity
OCX50_RS09290	COG0745	RESPONSE REGULATOR receiver
OCX50_RS09295	COG0583	DNA-binding transcription factor activity
OCX50_RS09305	COG5001	Diguanylate cyclase
OCX50_RS09305	COG3300	MHYT domain
OCX50_RS09310	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
OCX50_RS09340	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
OCX50_RS09345	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
OCX50_RS09350	COG0539	negative regulation of cytoplasmic translation
OCX50_RS09355	COG0776	regulation of translation
OCX50_RS09365	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
OCX50_RS09385	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
OCX50_RS09390	COG0602	queuosine metabolic process
OCX50_RS09395	COG3530	Putative quorum-sensing-regulated virulence factor
OCX50_RS09400	COG2096	Adenosyltransferase
OCX50_RS09405	COG2916	Histone family protein nucleoid-structuring protein H-NS
OCX50_RS09410	COG1757	Na H antiporter
OCX50_RS09415	COG1435	thymidine kinase activity
OCX50_RS09440	COG1737	Transcriptional regulator
OCX50_RS09445	COG1263	PTS System
OCX50_RS09445	COG2190	(PTS) system
OCX50_RS09445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCX50_RS09450	COG2723	6-phospho-beta-galactosidase activity
OCX50_RS09465	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
OCX50_RS09475	COG3550	peptidyl-serine autophosphorylation
OCX50_RS09555	COG3039	Transposase
OCX50_RS09565	COG4584	PFAM Integrase catalytic
OCX50_RS09570	COG1484	DNA-dependent DNA replication
OCX50_RS09580	COG2197	response regulator
OCX50_RS09700	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
OCX50_RS09705	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OCX50_RS09710	COG1397	ADP-ribosylglycohydrolase
OCX50_RS09755	COG3385	transposase activity
OCX50_RS09860	COG0071	Belongs to the small heat shock protein (HSP20) family
OCX50_RS09865	COG0542	response to heat
OCX50_RS09875	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
OCX50_RS09895	COG0501	Belongs to the peptidase M48B family
OCX50_RS09900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
OCX50_RS09990	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
OCX50_RS09995	COG0626	cystathionine gamma-synthase activity
OCX50_RS10005	COG2910	NAD(P)H-binding
OCX50_RS10010	COG0583	DNA-binding transcription factor activity
OCX50_RS10015	COG4977	sequence-specific DNA binding
OCX50_RS10015	COG1917	Cupin 2, conserved barrel domain protein
OCX50_RS10020	COG2200	EAL domain
OCX50_RS10025	COG2203	Gaf domain
OCX50_RS10025	COG2199	diguanylate cyclase activity
OCX50_RS10030	COG4774	siderophore transport
OCX50_RS10040	COG0583	DNA-binding transcription factor activity
OCX50_RS10045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
OCX50_RS10055	COG0517	IMP dehydrogenase activity
OCX50_RS10055	COG0617	tRNA 3'-terminal CCA addition
OCX50_RS10055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OCX50_RS10070	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCX50_RS10075	COG3046	protein related to deoxyribodipyrimidine photolyase
OCX50_RS10090	COG4235	cytochrome complex assembly
OCX50_RS10090	COG3088	subunit of a heme lyase
OCX50_RS10095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCX50_RS10105	COG3301	Polysulphide reductase, NrfD
OCX50_RS10110	COG0437	4 iron, 4 sulfur cluster binding
OCX50_RS10115	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
OCX50_RS10130	COG0247	lactate metabolic process
OCX50_RS10140	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
OCX50_RS10145	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
OCX50_RS10150	COG3012	SEC-C Motif Domain Protein
OCX50_RS10155	COG0840	transmembrane signaling receptor activity
OCX50_RS10160	COG1940	carbohydrate kinase activity
OCX50_RS10160	COG1846	Transcriptional regulator
OCX50_RS10165	COG3290	protein histidine kinase activity
OCX50_RS10170	COG4565	transcriptional regulatory protein
OCX50_RS10185	COG3181	Tripartite tricarboxylate transporter family receptor
OCX50_RS10190	COG1196	nuclear chromosome segregation
OCX50_RS10190	COG0741	lytic transglycosylase activity
OCX50_RS10190	COG0739	heme binding
OCX50_RS10200	COG2985	domain, Protein
OCX50_RS10200	COG0569	domain protein
OCX50_RS10215	COG0556	nucleotide-excision repair
OCX50_RS10225	COG0586	Pfam SNARE associated Golgi protein
OCX50_RS10230	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
OCX50_RS10235	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
OCX50_RS10240	COG2186	Transcriptional regulator
OCX50_RS10250	COG2719	SpoVR family
OCX50_RS10255	COG2718	Belongs to the UPF0229 family
OCX50_RS10260	COG2766	serine protein kinase
OCX50_RS10265	COG0514	ATP-dependent DNA helicase (RecQ)
OCX50_RS10270	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
OCX50_RS10275	COG0814	amino acid
OCX50_RS10310	COG0058	SHG alpha-glucan phosphorylase activity
OCX50_RS10320	COG0471	metal ion transport
OCX50_RS10325	COG3118	belongs to the thioredoxin family
OCX50_RS10335	COG1132	(ABC) transporter
OCX50_RS10340	COG1132	(ABC) transporter
OCX50_RS10370	COG2501	S4 domain
OCX50_RS10410	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
OCX50_RS10415	COG2329	Antibiotic biosynthesis monooxygenase
OCX50_RS10440	COG1742	UPF0060 membrane protein
OCX50_RS10455	COG0513	Belongs to the DEAD box helicase family
OCX50_RS10460	COG0386	Belongs to the glutathione peroxidase family
OCX50_RS10470	COG1181	Belongs to the D-alanine--D-alanine ligase family
OCX50_RS10475	COG3148	PFAM DTW domain containing protein
OCX50_RS10490	COG0730	response to heat
OCX50_RS10495	COG0583	DNA-binding transcription factor activity
OCX50_RS10515	COG3593	DNA synthesis involved in DNA repair
OCX50_RS10560	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
OCX50_RS10565	COG1011	Hydrolase
OCX50_RS10570	COG1473	amidohydrolase
OCX50_RS10580	COG0205	6-phosphofructokinase activity
OCX50_RS10590	COG1434	Gram-negative-bacterium-type cell wall biogenesis
OCX50_RS10595	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCX50_RS10605	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
OCX50_RS10610	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OCX50_RS10640	COG0588	phosphoglycerate mutase activity
OCX50_RS10650	COG0675	Transposase, IS605 OrfB family
OCX50_RS10670	COG2824	Alkylphosphonate utilization operon protein PhnA
OCX50_RS10720	COG2840	Smr protein MutS2
OCX50_RS10725	COG2890	protein-(glutamine-N5) methyltransferase activity
OCX50_RS10730	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
OCX50_RS10740	COG0513	Belongs to the DEAD box helicase family
OCX50_RS10745	COG5654	RES domain protein
OCX50_RS10755	COG0814	amino acid
OCX50_RS10760	COG1609	Transcriptional regulator
OCX50_RS10765	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCX50_RS10765	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCX50_RS10770	COG1105	Belongs to the carbohydrate kinase PfkB family
OCX50_RS10775	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCX50_RS10775	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
OCX50_RS10775	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
OCX50_RS10780	COG3313	Fe-S protein
OCX50_RS10785	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
OCX50_RS10790	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
OCX50_RS10795	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCX50_RS10800	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
OCX50_RS10810	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCX50_RS10835	COG0675	Transposase, IS605 OrfB family
OCX50_RS10850	COG5433	transposase activity
OCX50_RS10890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
OCX50_RS10895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
OCX50_RS10900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
OCX50_RS10905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
OCX50_RS10910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
OCX50_RS10915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCX50_RS10915	COG0072	phenylalanine-tRNA ligase activity
OCX50_RS10920	COG0776	regulation of translation
OCX50_RS10955	COG3300	MHYT domain
OCX50_RS10955	COG5001	Diguanylate cyclase
OCX50_RS10970	COG1609	Transcriptional regulator
OCX50_RS10975	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCX50_RS10980	COG1879	ABC-type sugar transport system periplasmic component
OCX50_RS10985	COG1172	Belongs to the binding-protein-dependent transport system permease family
OCX50_RS10990	COG1129	ABC transporter
OCX50_RS10995	COG1869	D-ribose catabolic process
OCX50_RS11000	COG0625	glutathione transferase activity
OCX50_RS11015	COG0037	tRNA processing
OCX50_RS11020	COG0589	response to stress
OCX50_RS11025	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCX50_RS11040	COG2217	Heavy metal translocating P-type atpase
OCX50_RS11050	COG2010	Cytochrome c
OCX50_RS11065	COG3278	Belongs to the heme-copper respiratory oxidase family
OCX50_RS11080	COG1956	GAF domain-containing protein
OCX50_RS11085	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
OCX50_RS11095	COG0308	aminopeptidase N
OCX50_RS11105	COG2902	Dehydrogenase
OCX50_RS11110	COG0167	dihydroorotate dehydrogenase activity
OCX50_RS11120	COG0116	Belongs to the methyltransferase superfamily
OCX50_RS11120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCX50_RS11130	COG0488	(ABC) transporter
OCX50_RS11145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
OCX50_RS11150	COG1067	ATP-dependent peptidase activity
OCX50_RS11160	COG3141	response to X-ray
OCX50_RS11175	COG2995	paraquat-inducible protein a
OCX50_RS11180	COG3008	intermembrane lipid transfer
OCX50_RS11185	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCX50_RS11185	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
OCX50_RS11200	COG0084	hydrolase, TatD family'
OCX50_RS11205	COG0470	DNA polymerase III
OCX50_RS11210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
OCX50_RS11215	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
OCX50_RS11220	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
OCX50_RS11225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCX50_RS11230	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
OCX50_RS11235	COG1028	Short-chain dehydrogenase reductase Sdr
OCX50_RS11245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
OCX50_RS11250	COG0416	fatty acid biosynthetic process
OCX50_RS11255	COG0333	Belongs to the bacterial ribosomal protein bL32 family
OCX50_RS11260	COG1399	metal-binding, possibly nucleic acid-binding protein
OCX50_RS11280	COG0564	pseudouridine synthase activity
OCX50_RS11285	COG1530	ribonuclease E activity
OCX50_RS11310	COG0840	transmembrane signaling receptor activity
OCX50_RS11315	COG1484	DNA-dependent DNA replication
OCX50_RS11320	COG4584	PFAM Integrase catalytic
OCX50_RS11325	COG0840	transmembrane signaling receptor activity
OCX50_RS11395	COG0625	glutathione transferase activity
OCX50_RS11400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCX50_RS11410	COG0583	DNA-binding transcription factor activity
OCX50_RS11420	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCX50_RS11450	COG1846	Transcriptional regulator
OCX50_RS11455	COG0583	DNA-binding transcription factor activity
OCX50_RS11465	COG2948	multi-organism process
OCX50_RS11515	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS11530	COG0306	phosphate transporter
OCX50_RS11535	COG0717	Belongs to the dCTP deaminase family
OCX50_RS11540	COG0572	uridine kinase
OCX50_RS11545	COG0489	protein tyrosine kinase activity
OCX50_RS11550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCX50_RS11550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCX50_RS11565	COG1254	Belongs to the acylphosphatase family
OCX50_RS11570	COG0840	transmembrane signaling receptor activity
OCX50_RS11575	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
OCX50_RS11590	COG0709	Synthesizes selenophosphate from selenide and ATP
OCX50_RS11595	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
OCX50_RS11600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCX50_RS11605	COG3437	response regulator, receiver
OCX50_RS11620	COG0675	Transposase, IS605 OrfB family
OCX50_RS11640	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
OCX50_RS11650	COG1643	Atp-dependent helicase
OCX50_RS11655	COG0617	tRNA 3'-terminal CCA addition
OCX50_RS11655	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
OCX50_RS11655	COG0517	IMP dehydrogenase activity
OCX50_RS11660	COG2197	response regulator
OCX50_RS11665	COG3039	Transposase
OCX50_RS11670	COG3385	transposase activity
OCX50_RS11675	COG3314	Sporulation integral membrane protein YlbJ
OCX50_RS11690	COG5433	transposase activity
OCX50_RS11740	COG3621	Patatin-like phospholipase
OCX50_RS11775	COG0697	spore germination
OCX50_RS11795	COG3077	Addiction module antitoxin, RelB DinJ family
OCX50_RS11800	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCX50_RS11815	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCX50_RS11845	COG3039	Transposase
OCX50_RS11850	COG0840	transmembrane signaling receptor activity
OCX50_RS11865	COG0583	DNA-binding transcription factor activity
OCX50_RS11870	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
OCX50_RS11880	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
OCX50_RS11885	COG2832	Protein of unknown function (DUF454)
OCX50_RS11890	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
OCX50_RS11900	COG0697	spore germination
OCX50_RS11910	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
OCX50_RS11915	COG0318	PFAM AMP-dependent synthetase and ligase
OCX50_RS11920	COG0596	Alpha beta hydrolase
OCX50_RS11930	COG1214	PFAM Peptidase M22, glycoprotease
OCX50_RS11945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
OCX50_RS11950	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
OCX50_RS11955	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
OCX50_RS11960	COG0131	Imidazoleglycerol-phosphate dehydratase
OCX50_RS11960	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCX50_RS11965	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
OCX50_RS11970	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
OCX50_RS11975	COG3437	response regulator, receiver
OCX50_RS11980	COG2199	diguanylate cyclase activity
OCX50_RS11985	COG0784	Response regulator, receiver
OCX50_RS11985	COG2198	Histidine kinase
OCX50_RS11985	COG2205	protein histidine kinase activity
OCX50_RS11990	COG0107	imidazoleglycerol-phosphate synthase activity
OCX50_RS11995	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
OCX50_RS11995	COG0140	phosphoribosyl-ATP diphosphatase activity
OCX50_RS12005	COG2378	regulation of single-species biofilm formation
OCX50_RS12010	COG0318	PFAM AMP-dependent synthetase and ligase
OCX50_RS12015	COG0675	Transposase, IS605 OrfB family
OCX50_RS12030	COG3134	Outer membrane lipoprotein
OCX50_RS12045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCX50_RS12065	COG3385	transposase activity
OCX50_RS12075	COG4681	YaeQ
OCX50_RS12085	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCX50_RS12085	COG1024	Enoyl-CoA hydratase
OCX50_RS12090	COG0183	Belongs to the thiolase family
OCX50_RS12095	COG0714	Associated with various cellular activities
OCX50_RS12125	COG1595	DNA-templated transcription, initiation
OCX50_RS12135	COG2067	long-chain fatty acid transport protein
OCX50_RS12140	COG2067	long-chain fatty acid transport protein
OCX50_RS12145	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
OCX50_RS12160	COG1301	dicarboxylic acid transport
OCX50_RS12165	COG3123	guanosine phosphorylase activity
OCX50_RS12170	COG1760	l-serine dehydratase
OCX50_RS12175	COG1760	l-serine dehydratase
OCX50_RS12180	COG3385	transposase activity
OCX50_RS12185	COG2951	lytic endotransglycosylase activity
OCX50_RS12190	COG3100	YcgL domain-containing protein
OCX50_RS12195	COG0850	regulation of cytokinetic process
OCX50_RS12200	COG2894	cell division
OCX50_RS12205	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
OCX50_RS12210	COG3099	Belongs to the UPF0263 family
OCX50_RS12215	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OCX50_RS12230	COG2996	Protein conserved in bacteria
OCX50_RS12235	COG0675	Transposase, IS605 OrfB family
OCX50_RS12265	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
OCX50_RS12270	COG0697	spore germination
OCX50_RS12275	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
OCX50_RS12280	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCX50_RS12295	COG0307	riboflavin synthase, alpha
OCX50_RS12305	COG0534	Mate efflux family protein
OCX50_RS12375	COG0417	DNA replication proofreading
OCX50_RS12390	COG1560	Kdo2-lipid A biosynthetic process
OCX50_RS12395	COG1560	Kdo2-lipid A biosynthetic process
OCX50_RS12405	COG0583	DNA-binding transcription factor activity
OCX50_RS12410	COG0673	inositol 2-dehydrogenase activity
OCX50_RS12415	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
OCX50_RS12430	COG0583	DNA-binding transcription factor activity
OCX50_RS12435	COG5433	transposase activity
OCX50_RS12440	COG0583	DNA-binding transcription factor activity
OCX50_RS12450	COG2723	6-phospho-beta-galactosidase activity
OCX50_RS12455	COG0583	DNA-binding transcription factor activity
OCX50_RS12470	COG0243	molybdopterin cofactor binding
OCX50_RS12475	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
OCX50_RS12490	COG0583	DNA-binding transcription factor activity
OCX50_RS12495	COG1129	ABC transporter
OCX50_RS12500	COG1172	Belongs to the binding-protein-dependent transport system permease family
OCX50_RS12505	COG1172	Belongs to the binding-protein-dependent transport system permease family
OCX50_RS12520	COG0702	epimerase
OCX50_RS12525	COG1073	alpha beta
OCX50_RS12530	COG1073	alpha beta
OCX50_RS12580	COG2003	Belongs to the UPF0758 family
OCX50_RS12620	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
OCX50_RS12640	COG0730	response to heat
OCX50_RS12650	COG1028	Short-chain dehydrogenase reductase Sdr
OCX50_RS12660	COG1024	Enoyl-CoA hydratase
OCX50_RS12670	COG1024	Enoyl-CoA hydratase
OCX50_RS12675	COG1960	acyl-CoA dehydrogenase activity
OCX50_RS12685	COG1960	acyl-CoA dehydrogenase activity
OCX50_RS12690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
OCX50_RS12695	COG1024	Enoyl-CoA hydratase
OCX50_RS12720	COG1584	GPR1 FUN34 yaaH family protein
OCX50_RS12725	COG3228	Belongs to the MtfA family
OCX50_RS12735	COG1115	amino acid carrier protein
OCX50_RS12740	COG1024	Enoyl-CoA hydratase
OCX50_RS12755	COG3162	membrane
OCX50_RS12760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCX50_RS12765	COG0488	(ABC) transporter
OCX50_RS12770	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCX50_RS12775	COG0776	regulation of translation
OCX50_RS12780	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
OCX50_RS12785	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
OCX50_RS12790	COG0740	serine-type endopeptidase activity
OCX50_RS12795	COG0544	peptidyl-prolyl cis-trans isomerase activity
OCX50_RS12805	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
OCX50_RS12810	COG4591	ABC-type transport system involved in lipoprotein release permease component
OCX50_RS12815	COG1136	(ABC) transporter
OCX50_RS12820	COG4591	ABC-type transport system involved in lipoprotein release permease component
OCX50_RS12830	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
OCX50_RS12835	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
OCX50_RS12845	COG0697	spore germination
OCX50_RS12855	COG2062	phosphohistidine phosphatase, SixA
OCX50_RS12865	COG0500	methyltransferase
OCX50_RS12875	COG1846	Transcriptional regulator
OCX50_RS12935	COG0519	Catalyzes the synthesis of GMP from XMP
OCX50_RS12935	COG0518	GMP synthase (glutamine-hydrolyzing) activity
OCX50_RS12940	COG0516	GMP reductase activity
OCX50_RS12940	COG0517	IMP dehydrogenase activity
OCX50_RS12950	COG0366	Alpha amylase catalytic
OCX50_RS12950	COG1874	Beta-galactosidase
OCX50_RS12965	COG1570	exodeoxyribonuclease VII activity
OCX50_RS12975	COG2885	chlorophyll binding
OCX50_RS12995	COG2154	pterin-4-alpha-carbinolamine dehydratase
OCX50_RS13005	COG3768	UPF0283 membrane protein
OCX50_RS13010	COG3106	COG3106 Predicted ATPase
OCX50_RS13025	COG1842	Phage shock protein A
OCX50_RS13030	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
OCX50_RS13045	COG4171	peptide transport system, permease
OCX50_RS13055	COG4172	Belongs to the ABC transporter superfamily
OCX50_RS13065	COG1609	Transcriptional regulator
OCX50_RS13070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCX50_RS13070	COG1263	PTS System
OCX50_RS13075	COG2723	6-phospho-beta-galactosidase activity
OCX50_RS13080	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
OCX50_RS13085	COG1286	toxin biosynthetic process
OCX50_RS13090	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
OCX50_RS13095	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
OCX50_RS13100	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
OCX50_RS13105	COG1674	ftsk spoiiie
OCX50_RS13105	COG0531	amino acid
OCX50_RS13115	COG0686	Belongs to the AlaDH PNT family
OCX50_RS13120	COG0492	ferredoxin-NADP+ reductase activity
OCX50_RS13125	COG3706	GGDEF domain
OCX50_RS13130	COG3134	Outer membrane lipoprotein
OCX50_RS13135	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
OCX50_RS13140	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
OCX50_RS13145	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
OCX50_RS13150	COG0542	response to heat
OCX50_RS13155	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
OCX50_RS13160	COG1278	Cold shock
OCX50_RS13165	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
OCX50_RS13180	COG1944	ATP diphosphatase activity
OCX50_RS13185	COG2116	formate transmembrane transporter activity
OCX50_RS13190	COG1882	Formate acetyltransferase
OCX50_RS13195	COG2983	Belongs to the UPF0260 family
OCX50_RS13205	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
OCX50_RS13210	COG0045	succinate-CoA ligase (ADP-forming) activity
OCX50_RS13215	COG0508	dehydrogenase complex catalyzes the overall conversion of
OCX50_RS13220	COG0567	Dehydrogenase, E1 component
OCX50_RS13235	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
OCX50_RS13240	COG2009	succinate dehydrogenase
OCX50_RS13260	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
OCX50_RS13265	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCX50_RS13265	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
OCX50_RS13275	COG3069	C4-dicarboxylate transmembrane transporter activity
OCX50_RS13290	COG1451	nucleotide metabolic process
OCX50_RS13305	COG0254	rRNA binding
OCX50_RS13310	COG0257	Belongs to the bacterial ribosomal protein bL36 family
OCX50_RS13325	COG1129	ABC transporter
OCX50_RS13330	COG1879	ABC-type sugar transport system periplasmic component
OCX50_RS13335	COG1069	ribulokinase activity
OCX50_RS13345	COG2160	L-arabinose isomerase activity
OCX50_RS13350	COG0583	DNA-binding transcription factor activity
OCX50_RS13355	COG0436	Aminotransferase
OCX50_RS13360	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
OCX50_RS13375	COG0392	lysyltransferase activity
OCX50_RS13375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
OCX50_RS13380	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
OCX50_RS13490	COG1802	Transcriptional regulator
OCX50_RS13490	COG4626	Terminase
OCX50_RS13545	COG3646	Phage regulatory protein
OCX50_RS13560	COG1846	Transcriptional regulator
OCX50_RS13580	COG1396	sequence-specific DNA binding
OCX50_RS13585	COG1396	sequence-specific DNA binding
OCX50_RS13655	COG0582	viral genome integration into host DNA
OCX50_RS13660	COG2925	Exonuclease
OCX50_RS13670	COG3345	alpha-galactosidase
OCX50_RS13675	COG1380	Effector of murein hydrolase LrgA
OCX50_RS13680	COG1346	cytolysis
OCX50_RS13685	COG0295	cytidine deaminase activity
OCX50_RS13690	COG1022	Amp-dependent synthetase and ligase
OCX50_RS13705	COG0861	Integral membrane protein TerC family
OCX50_RS13710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCX50_RS13715	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
OCX50_RS13720	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
OCX50_RS13760	COG4771	TonB-dependent receptor
OCX50_RS13765	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCX50_RS13770	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
OCX50_RS13775	COG1120	ATPase activity
OCX50_RS13790	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OCX50_RS13800	COG1028	Short-chain dehydrogenase reductase Sdr
OCX50_RS13805	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
OCX50_RS13810	COG1535	isochorismatase
OCX50_RS13810	COG3433	isochorismatase activity
OCX50_RS13815	COG1021	2,3-dihydroxybenzoate-AMP ligase
OCX50_RS13840	COG3300	MHYT domain
OCX50_RS13840	COG5001	Diguanylate cyclase
OCX50_RS13855	COG0840	transmembrane signaling receptor activity
OCX50_RS13860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCX50_RS13865	COG3788	relative of glutathione S-transferase, MAPEG superfamily
OCX50_RS13870	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
OCX50_RS13875	COG0563	adenylate kinase activity
OCX50_RS13880	COG0326	Molecular chaperone. Has ATPase activity
OCX50_RS13885	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
OCX50_RS13905	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS13930	COG0659	secondary active sulfate transmembrane transporter activity
OCX50_RS13945	COG3335	DDE superfamily endonuclease
OCX50_RS13950	COG2308	Evidence 4 Homologs of previously reported genes of
OCX50_RS13990	COG0672	)-iron permease
OCX50_RS14015	COG2814	Major facilitator Superfamily
OCX50_RS14035	COG1136	(ABC) transporter
OCX50_RS14040	COG0577	efflux transmembrane transporter activity
OCX50_RS14060	COG1139	Iron-sulfur cluster binding protein
OCX50_RS14065	COG0247	lactate metabolic process
OCX50_RS14070	COG1620	l-lactate permease
OCX50_RS14075	COG0583	DNA-binding transcription factor activity
OCX50_RS14100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
OCX50_RS14105	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
OCX50_RS14105	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCX50_RS14110	COG0527	aspartate kinase activity
OCX50_RS14120	COG1368	sulfuric ester hydrolase activity
OCX50_RS14125	COG0393	Putative heavy-metal-binding
OCX50_RS14130	COG1252	NADH dehydrogenase
OCX50_RS14135	COG3150	esterase
OCX50_RS14140	COG1164	Oligoendopeptidase f
OCX50_RS14145	COG1164	Oligoendopeptidase f
OCX50_RS14150	COG2354	Protein conserved in bacteria
OCX50_RS14165	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCX50_RS14170	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
OCX50_RS14205	COG0537	adenosine 5'-monophosphoramidase activity
OCX50_RS14220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
OCX50_RS14245	COG1301	dicarboxylic acid transport
OCX50_RS14255	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
OCX50_RS14270	COG0444	Belongs to the ABC transporter superfamily
OCX50_RS14275	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCX50_RS14280	COG0601	transmembrane transport
OCX50_RS14290	COG2095	MarC family integral membrane protein
OCX50_RS14295	COG1454	alcohol dehydrogenase
OCX50_RS14295	COG1012	belongs to the aldehyde dehydrogenase family
OCX50_RS14305	COG3275	phosphorelay sensor kinase activity
OCX50_RS14310	COG3279	Response regulator of the LytR AlgR family
OCX50_RS14315	COG1966	Carbon starvation protein
OCX50_RS14320	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
OCX50_RS14320	COG3264	Mechanosensitive ion channel
OCX50_RS14330	COG1566	PFAM secretion protein HlyD family protein
OCX50_RS14335	COG1061	Type III restriction enzyme res subunit
OCX50_RS14340	COG2027	D-alanyl-D-alanine carboxypeptidase
OCX50_RS14345	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
OCX50_RS14355	COG0436	Aminotransferase
OCX50_RS14365	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
OCX50_RS14380	COG0840	transmembrane signaling receptor activity
OCX50_RS14390	COG0697	spore germination
OCX50_RS14400	COG0675	Transposase, IS605 OrfB family
OCX50_RS14405	COG4657	Part of a membrane complex involved in electron transport
OCX50_RS14410	COG2878	Part of a membrane complex involved in electron transport
OCX50_RS14420	COG4658	electron transport chain
OCX50_RS14425	COG4659	FMN binding
OCX50_RS14430	COG4660	Part of a membrane complex involved in electron transport
OCX50_RS14435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
OCX50_RS14440	COG0346	lactoylglutathione lyase activity
OCX50_RS14460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
OCX50_RS14470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCX50_RS14475	COG1086	Polysaccharide biosynthesis protein
OCX50_RS14480	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
OCX50_RS14490	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
OCX50_RS14495	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OCX50_RS14510	COG2089	acid synthase
OCX50_RS14550	COG1334	flagellar protein FlaG
OCX50_RS14555	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCX50_RS14560	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
OCX50_RS14575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCX50_RS14575	COG0301	tRNA thio-modification
OCX50_RS14585	COG4953	penicillin-binding protein 1C
OCX50_RS14590	COG2373	Large extracellular alpha-helical protein
OCX50_RS14600	COG0628	permease
OCX50_RS14605	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCX50_RS14615	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
OCX50_RS14625	COG4160	amino acid transport
OCX50_RS14635	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS14645	COG2431	L-lysine efflux transmembrane transporter activity
OCX50_RS14655	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OCX50_RS14660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS14685	COG1393	Belongs to the ArsC family
OCX50_RS14695	COG4783	chaperone-mediated protein folding
OCX50_RS14700	COG0425	Belongs to the sulfur carrier protein TusA family
OCX50_RS14725	COG3842	ATPase activity
OCX50_RS14730	COG3833	ABC-type maltose transport systems, permease component
OCX50_RS14735	COG1175	transmembrane transport
OCX50_RS14745	COG3081	Nucleoid-associated protein
OCX50_RS14750	COG3082	Protein of unknown function (DUF1414)
OCX50_RS14755	COG3083	sulfuric ester hydrolase activity
OCX50_RS14760	COG4771	TonB-dependent receptor
OCX50_RS14765	COG1770	oligopeptidase
OCX50_RS14785	COG4574	serine-type endopeptidase inhibitor activity
OCX50_RS14790	COG3085	chromosome segregation
OCX50_RS14800	COG0287	Prephenate dehydrogenase
OCX50_RS14800	COG1605	Chorismate mutase
OCX50_RS14805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
OCX50_RS14810	COG0584	glycerophosphoryl diester phosphodiesterase
OCX50_RS14820	COG1349	DNA-binding transcription factor activity
OCX50_RS14825	COG2271	Major facilitator Superfamily
OCX50_RS14830	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
OCX50_RS14835	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
OCX50_RS14840	COG0583	DNA-binding transcription factor activity
OCX50_RS14860	COG0656	L-ascorbic acid biosynthetic process
OCX50_RS14865	COG2814	Major facilitator Superfamily
OCX50_RS14875	COG1294	oxidase, subunit
OCX50_RS14880	COG1271	oxidase subunit
OCX50_RS14885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCX50_RS14895	COG2979	Protein of unknown function (DUF533)
OCX50_RS14915	COG0583	DNA-binding transcription factor activity
OCX50_RS14925	COG2807	transmembrane transport
OCX50_RS14935	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
OCX50_RS14945	COG2801	Transposase and inactivated derivatives
OCX50_RS14965	COG1061	Type III restriction enzyme res subunit
OCX50_RS14990	COG1166	arginine decarboxylase activity
OCX50_RS14995	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCX50_RS15010	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
OCX50_RS15030	COG0583	DNA-binding transcription factor activity
OCX50_RS15045	COG0840	transmembrane signaling receptor activity
OCX50_RS15050	COG0302	gtp cyclohydrolase
OCX50_RS15060	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
OCX50_RS15065	COG2267	carboxylic ester hydrolase activity
OCX50_RS15070	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
OCX50_RS15085	COG0314	molybdopterin synthase activity
OCX50_RS15090	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
OCX50_RS15095	COG0315	cyclic pyranopterin monophosphate synthase activity
OCX50_RS15100	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCX50_RS15105	COG3005	denitrification pathway
OCX50_RS15115	COG0348	domain, Protein
OCX50_RS15120	COG0437	4 iron, 4 sulfur cluster binding
OCX50_RS15125	COG0243	molybdopterin cofactor binding
OCX50_RS15135	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCX50_RS15135	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCX50_RS15140	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
OCX50_RS15145	COG3850	Histidine kinase
OCX50_RS15150	COG2197	response regulator
OCX50_RS15175	COG0391	Required for morphogenesis under gluconeogenic growth conditions
OCX50_RS15185	COG0121	glutamine amidotransferase
OCX50_RS15190	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
OCX50_RS15195	COG1960	acyl-CoA dehydrogenase activity
OCX50_RS15210	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
OCX50_RS15215	COG0328	RNA-DNA hybrid ribonuclease activity
OCX50_RS15220	COG2226	methyltransferase
OCX50_RS15225	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
OCX50_RS15235	COG0741	lytic transglycosylase activity
OCX50_RS15235	COG1388	LysM domain
OCX50_RS15250	COG1607	acyl-coa hydrolase
OCX50_RS15265	COG0741	lytic transglycosylase activity
OCX50_RS15275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
OCX50_RS15295	COG2911	Protein conserved in bacteria
OCX50_RS15300	COG0729	surface antigen
OCX50_RS15310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
OCX50_RS15320	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
OCX50_RS15325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
OCX50_RS15330	COG4134	Bacterial extracellular solute-binding protein
OCX50_RS15340	COG4136	ATPase activity
OCX50_RS15345	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
OCX50_RS15350	COG2951	lytic endotransglycosylase activity
OCX50_RS15355	COG3385	transposase activity
OCX50_RS15360	COG1846	Transcriptional regulator
OCX50_RS15370	COG0033	Phosphoglucomutase
OCX50_RS15375	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
OCX50_RS15380	COG0596	Alpha beta hydrolase
OCX50_RS15395	COG0716	FMN binding
OCX50_RS15405	COG0735	belongs to the Fur family
OCX50_RS15410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCX50_RS15420	COG1263	PTS System
OCX50_RS15420	COG2190	(PTS) system
OCX50_RS15420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCX50_RS15425	COG0363	glucosamine-6-phosphate deaminase activity
OCX50_RS15430	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
OCX50_RS15435	COG1940	carbohydrate kinase activity
OCX50_RS15435	COG1846	Transcriptional regulator
OCX50_RS15440	COG2194	sulfuric ester hydrolase activity
OCX50_RS15445	COG0217	transcriptional regulatory protein
OCX50_RS15450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
OCX50_RS15455	COG1801	Protein of unknown function DUF72
OCX50_RS15460	COG4106	trans-aconitate 2-methyltransferase activity
OCX50_RS15465	COG0500	methyltransferase
OCX50_RS15485	COG0583	DNA-binding transcription factor activity
OCX50_RS15490	COG0791	NLP P60 protein
OCX50_RS15505	COG1309	transcriptional regulator
OCX50_RS15515	COG1454	alcohol dehydrogenase
OCX50_RS15540	COG0534	Mate efflux family protein
OCX50_RS15550	COG2841	Protein conserved in bacteria
OCX50_RS15555	COG1013	pyruvate-flavodoxin oxidoreductase activity
OCX50_RS15555	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
OCX50_RS15555	COG0674	pyruvate-flavodoxin oxidoreductase activity
OCX50_RS15555	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
OCX50_RS15565	COG0633	Ferredoxin
OCX50_RS15565	COG3217	Mosc domain protein beta barrel domain protein
OCX50_RS15565	COG0633	Ferredoxin
OCX50_RS15565	COG3217	Mosc domain protein beta barrel domain protein
OCX50_RS15570	COG0501	Belongs to the peptidase M48B family
OCX50_RS15575	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
OCX50_RS15580	COG1073	alpha beta
OCX50_RS15580	COG2226	methyltransferase
OCX50_RS15585	COG0156	8-amino-7-oxononanoate synthase activity
OCX50_RS15590	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
OCX50_RS15610	COG0017	Asparaginyl-tRNA synthetase
OCX50_RS15615	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
OCX50_RS15625	COG1473	amidohydrolase
OCX50_RS15630	COG3069	C4-dicarboxylate transmembrane transporter activity
OCX50_RS15645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS15660	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS15665	COG1393	Belongs to the ArsC family
OCX50_RS15670	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
OCX50_RS15675	COG1876	peptidase activity
OCX50_RS15685	COG3263	regulation of cellular component size
OCX50_RS15695	COG1280	lysine exporter protein (LysE YggA)
OCX50_RS15720	COG1957	nucleoside hydrolase
OCX50_RS15725	COG0564	pseudouridine synthase activity
OCX50_RS15735	COG1454	alcohol dehydrogenase
OCX50_RS15740	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCX50_RS15745	COG0702	epimerase
OCX50_RS15750	COG2914	Belongs to the UPF0125 (RnfH) family
OCX50_RS15755	COG2867	negative regulation of translational initiation
OCX50_RS15760	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
OCX50_RS15770	COG0582	viral genome integration into host DNA
OCX50_RS15800	COG2194	sulfuric ester hydrolase activity
OCX50_RS15805	COG3039	Transposase
OCX50_RS15820	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
OCX50_RS15825	COG3039	Transposase
OCX50_RS15880	COG4584	PFAM Integrase catalytic
OCX50_RS15885	COG1484	DNA-dependent DNA replication
OCX50_RS15895	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
OCX50_RS15955	COG3311	Transcriptional regulator
OCX50_RS15995	COG0246	Mannitol dehydrogenase
OCX50_RS16000	COG2721	sulfolactate sulfo-lyase activity
OCX50_RS16010	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCX50_RS16015	COG0800	Aldolase
OCX50_RS16030	COG3153	acetyltransferase
OCX50_RS16060	COG0259	pyridoxamine-phosphate oxidase activity
OCX50_RS16075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCX50_RS16075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
OCX50_RS16080	COG3385	transposase activity
OCX50_RS16085	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
OCX50_RS16100	COG0457	Tetratricopeptide repeat
OCX50_RS16110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCX50_RS16115	COG1138	Cytochrome C-type biogenesis protein
OCX50_RS16120	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
OCX50_RS16125	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCX50_RS16130	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCX50_RS16135	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
OCX50_RS16150	COG0835	chemotaxis
OCX50_RS16160	COG1192	Involved in chromosome partitioning
OCX50_RS16165	COG1360	Flagellar Motor Protein
OCX50_RS16170	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OCX50_RS16180	COG0643	Histidine kinase
OCX50_RS16180	COG0784	Response regulator, receiver
OCX50_RS16180	COG2198	Histidine kinase
OCX50_RS16185	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
OCX50_RS16215	COG5433	transposase activity
OCX50_RS16230	COG1684	flagellar biosynthetic protein fliR
OCX50_RS16285	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
OCX50_RS16295	COG1677	Flagellar hook-basal body complex protein FliE
OCX50_RS16305	COG1393	Belongs to the ArsC family
OCX50_RS16310	COG0798	PFAM Bile acid sodium symporter
OCX50_RS16315	COG0640	Transcriptional regulator
OCX50_RS16325	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCX50_RS16340	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCX50_RS16345	COG0444	Belongs to the ABC transporter superfamily
OCX50_RS16350	COG4608	Belongs to the ABC transporter superfamily
OCX50_RS16360	COG2971	BadF BadG BcrA BcrD
OCX50_RS16370	COG0840	transmembrane signaling receptor activity
OCX50_RS16390	COG3724	N-succinylarginine dihydrolase activity
OCX50_RS16395	COG0616	signal peptide processing
OCX50_RS16400	COG1028	Short-chain dehydrogenase reductase Sdr
OCX50_RS16405	COG0583	DNA-binding transcription factor activity
OCX50_RS16415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
OCX50_RS16425	COG0583	DNA-binding transcription factor activity
OCX50_RS16430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
OCX50_RS16435	COG1881	PFAM PEBP family protein
OCX50_RS16445	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
OCX50_RS16445	COG3408	Glycogen debranching enzyme
OCX50_RS16450	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OCX50_RS16455	COG0739	heme binding
OCX50_RS16460	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
OCX50_RS16485	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
OCX50_RS16495	COG3091	SprT-like family
OCX50_RS16505	COG1385	rRNA (uridine-N3-)-methyltransferase activity
OCX50_RS16510	COG0189	ligase activity
OCX50_RS16520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
OCX50_RS16540	COG1115	amino acid carrier protein
OCX50_RS16545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
OCX50_RS16560	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
OCX50_RS16570	COG1301	dicarboxylic acid transport
OCX50_RS16575	COG2877	3-deoxy-8-phosphooctulonate synthase activity
OCX50_RS16580	COG2912	Transglutaminase-like superfamily
OCX50_RS16590	COG2890	protein-(glutamine-N5) methyltransferase activity
OCX50_RS16595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
OCX50_RS16600	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
OCX50_RS16605	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
OCX50_RS16610	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
OCX50_RS16620	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
OCX50_RS16625	COG0193	aminoacyl-tRNA hydrolase activity
OCX50_RS16630	COG0012	GTP binding
OCX50_RS16675	COG0490	domain, Protein
OCX50_RS16675	COG0471	metal ion transport
OCX50_RS16685	COG0657	acetylesterase activity
OCX50_RS16700	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCX50_RS16705	COG2801	Transposase and inactivated derivatives
OCX50_RS16725	COG3039	Transposase
OCX50_RS16745	COG3039	Transposase
OCX50_RS16755	COG1012	belongs to the aldehyde dehydrogenase family
OCX50_RS16765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
OCX50_RS16780	COG0180	Tryptophanyl-tRNA synthetase
OCX50_RS16785	COG0546	phosphoglycolate phosphatase activity
OCX50_RS16790	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
OCX50_RS16795	COG0338	D12 class N6 adenine-specific DNA methyltransferase
OCX50_RS16805	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
OCX50_RS16810	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
OCX50_RS16840	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
OCX50_RS16845	COG0583	DNA-binding transcription factor activity
OCX50_RS16860	COG0583	DNA-binding transcription factor activity
OCX50_RS16875	COG0739	heme binding
OCX50_RS16885	COG1511	domain protein
OCX50_RS16885	COG3264	Mechanosensitive ion channel
OCX50_RS16890	COG0584	glycerophosphoryl diester phosphodiesterase
OCX50_RS16900	COG1053	succinate dehydrogenase
OCX50_RS16905	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
OCX50_RS16910	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OCX50_RS16915	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
OCX50_RS16920	COG3385	transposase activity
OCX50_RS16935	COG3214	Protein conserved in bacteria
OCX50_RS16940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
OCX50_RS16960	COG0300	oxidoreductase activity
OCX50_RS16980	COG4067	protein conserved in archaea
OCX50_RS16980	COG0189	ligase activity
OCX50_RS16985	COG0516	GMP reductase activity
OCX50_RS16995	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
OCX50_RS17000	COG2011	ABC-type metal ion transport system permease component
OCX50_RS17010	COG1464	Belongs to the NlpA lipoprotein family
OCX50_RS17025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCX50_RS17035	COG2199	diguanylate cyclase activity
OCX50_RS17045	COG2199	diguanylate cyclase activity
OCX50_RS17050	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCX50_RS17065	COG1278	Cold shock
OCX50_RS17070	COG1335	isochorismatase
OCX50_RS17075	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
OCX50_RS17080	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
OCX50_RS17085	COG1702	phosphate starvation-inducible protein PhoH
OCX50_RS17090	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
OCX50_RS17095	COG4535	Mg2 and Co2 transporter CorC
OCX50_RS17100	COG0815	Transfers the fatty acyl group on membrane lipoproteins
OCX50_RS17105	COG2888	peptidyl-tyrosine sulfation
OCX50_RS17110	COG0495	leucyl-tRNA aminoacylation
OCX50_RS17130	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
OCX50_RS17135	COG0799	negative regulation of ribosome biogenesis
OCX50_RS17140	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
OCX50_RS17145	COG0768	penicillin binding
OCX50_RS17150	COG0772	Belongs to the SEDS family
OCX50_RS17155	COG2951	lytic endotransglycosylase activity
OCX50_RS17160	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
OCX50_RS17165	COG1686	Belongs to the peptidase S11 family
OCX50_RS17170	COG2921	Belongs to the UPF0250 family
OCX50_RS17175	COG0321	lipoyl(octanoyl) transferase activity
OCX50_RS17180	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
OCX50_RS17190	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
OCX50_RS17205	COG0789	Transcriptional regulator
OCX50_RS17220	COG1970	mechanosensitive ion channel activity
OCX50_RS17225	COG4974	Belongs to the 'phage' integrase family
OCX50_RS17235	COG0312	modulator of DNA gyrase
OCX50_RS17245	COG0312	modulator of DNA gyrase
OCX50_RS17265	COG0826	peptidase U32
OCX50_RS17270	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
OCX50_RS17275	COG1422	Protein of unknown function (DUF1090)
OCX50_RS17280	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OCX50_RS17285	COG2211	Major facilitator Superfamily
OCX50_RS17290	COG1185	polyribonucleotide nucleotidyltransferase activity
OCX50_RS17295	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
OCX50_RS17300	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
OCX50_RS17305	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
OCX50_RS17310	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
OCX50_RS17315	COG0195	Participates in both transcription termination and antitermination
OCX50_RS17320	COG0779	Required for maturation of 30S ribosomal subunits
OCX50_RS17335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
OCX50_RS17340	COG0149	triose-phosphate isomerase activity
OCX50_RS17345	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
OCX50_RS17350	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
OCX50_RS17360	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
OCX50_RS17365	COG1534	Rna-binding protein
OCX50_RS17380	COG1360	Flagellar Motor Protein
OCX50_RS17385	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
OCX50_RS17390	COG1722	exodeoxyribonuclease VII activity
OCX50_RS17395	COG0142	geranyltranstransferase activity
OCX50_RS17400	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
OCX50_RS17405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
OCX50_RS17410	COG0601	transmembrane transport
OCX50_RS17430	COG4172	Belongs to the ABC transporter superfamily
OCX50_RS17435	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
OCX50_RS17440	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
OCX50_RS17445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
OCX50_RS17450	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
OCX50_RS17465	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCX50_RS17465	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
OCX50_RS17470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
OCX50_RS17480	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
OCX50_RS17490	COG3381	protein complex oligomerization
OCX50_RS17510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OCX50_RS17515	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
OCX50_RS17520	COG0511	ligase activity, forming carbon-carbon bonds
OCX50_RS17525	COG0439	Biotin carboxylase
OCX50_RS17530	COG3924	membrane
OCX50_RS17535	COG4145	pantothenate transmembrane transporter activity
OCX50_RS17540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCX50_RS17540	COG2190	(PTS) system
OCX50_RS17540	COG1263	PTS System
OCX50_RS17545	COG0583	DNA-binding transcription factor activity
OCX50_RS17550	COG0604	alcohol dehydrogenase
OCX50_RS17555	COG2264	protein methyltransferase activity
OCX50_RS17575	COG0778	Nitroreductase
OCX50_RS17580	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCX50_RS17580	COG1902	pentaerythritol trinitrate reductase activity
OCX50_RS17585	COG0616	signal peptide processing
OCX50_RS17605	COG3139	Protein of unknown function (DUF1315)
OCX50_RS17610	COG0252	asparaginase activity
OCX50_RS17615	COG0786	glutamate:sodium symporter activity
OCX50_RS17630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
OCX50_RS17635	COG0384	phenazine biosynthesis protein PhzF
OCX50_RS17640	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
OCX50_RS17645	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCX50_RS17650	COG0175	sulfate reduction
OCX50_RS17655	COG2113	Glycine betaine
OCX50_RS17660	COG4176	ABC-type proline glycine betaine transport system permease component
OCX50_RS17665	COG4175	Glycine betaine
OCX50_RS17675	COG3610	response to peptide
OCX50_RS17690	COG2966	Psort location CytoplasmicMembrane, score
OCX50_RS17700	COG0521	Mo-molybdopterin cofactor biosynthetic process
OCX50_RS17720	COG2313	pseudouridylate synthase activity
OCX50_RS17725	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
OCX50_RS17730	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCX50_RS17730	COG2146	nitrite reductase [NAD(P)H] activity
OCX50_RS17735	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCX50_RS17735	COG2146	nitrite reductase [NAD(P)H] activity
OCX50_RS17740	COG1116	anion transmembrane transporter activity
OCX50_RS17745	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
OCX50_RS17750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
OCX50_RS17750	COG1116	anion transmembrane transporter activity
OCX50_RS17760	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCX50_RS17760	COG1648	precorrin-2 dehydrogenase activity
OCX50_RS17765	COG0243	molybdopterin cofactor binding
OCX50_RS17790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
OCX50_RS17805	COG1073	alpha beta
OCX50_RS17810	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
OCX50_RS17815	COG2195	Cleaves the N-terminal amino acid of tripeptides
OCX50_RS17820	COG4608	Belongs to the ABC transporter superfamily
OCX50_RS17825	COG0444	Belongs to the ABC transporter superfamily
OCX50_RS17835	COG4239	(ABC) transporter, permease
OCX50_RS17840	COG4174	ABC transporter (Permease)
OCX50_RS17855	COG0811	peptide transport
OCX50_RS17860	COG0811	peptide transport
OCX50_RS17865	COG0848	biopolymer transport protein
OCX50_RS17930	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCX50_RS17935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCX50_RS17940	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCX50_RS17945	COG0840	transmembrane signaling receptor activity
OCX50_RS17955	COG1278	Cold shock
OCX50_RS18000	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
OCX50_RS18005	COG1162	GTPase activity
OCX50_RS18010	COG0688	phosphatidylethanolamine metabolic process
OCX50_RS18015	COG4628	conserved protein (DUF2132)
OCX50_RS18035	COG3300	MHYT domain
OCX50_RS18035	COG5001	Diguanylate cyclase
OCX50_RS18040	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
OCX50_RS18060	COG3039	Transposase
OCX50_RS18090	COG4974	Belongs to the 'phage' integrase family
OCX50_RS18100	COG3385	transposase activity
OCX50_RS18105	COG5002	protein histidine kinase activity
OCX50_RS18105	COG5001	Diguanylate cyclase
OCX50_RS18105	COG3447	MASE1 domain protein
OCX50_RS18115	COG3447	MASE1 domain protein
OCX50_RS18115	COG5001	Diguanylate cyclase
OCX50_RS18115	COG5002	protein histidine kinase activity
OCX50_RS18135	COG0582	viral genome integration into host DNA
OCX50_RS18165	COG1132	(ABC) transporter
OCX50_RS18175	COG2897	thiosulfate sulfurtransferase activity
OCX50_RS18180	COG2066	Belongs to the glutaminase family
OCX50_RS18185	COG3171	Protein conserved in bacteria
OCX50_RS18190	COG0220	tRNA (guanine-N7-)-methyltransferase activity
OCX50_RS18195	COG4935	Belongs to the peptidase S8 family
OCX50_RS18195	COG2234	aminopeptidase activity
OCX50_RS18200	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
OCX50_RS18205	COG2200	EAL domain
OCX50_RS18210	COG1090	epimerase
OCX50_RS18215	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
OCX50_RS18220	COG4181	ATPase activity
OCX50_RS18230	COG0784	Response regulator, receiver
OCX50_RS18230	COG0835	chemotaxis
OCX50_RS18250	COG0675	Transposase, IS605 OrfB family
OCX50_RS18265	COG0517	IMP dehydrogenase activity
OCX50_RS18265	COG0516	GMP reductase activity
OCX50_RS18270	COG0488	(ABC) transporter
OCX50_RS18280	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
OCX50_RS18315	COG3039	Transposase
OCX50_RS18320	COG0789	Transcriptional regulator
OCX50_RS18335	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
OCX50_RS18345	COG0668	transmembrane transport
OCX50_RS18355	COG2731	YhcH YjgK YiaL family protein
OCX50_RS18365	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCX50_RS18370	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCX50_RS18375	COG3227	Zinc metalloprotease (Elastase)
OCX50_RS18380	COG0583	DNA-binding transcription factor activity
OCX50_RS18385	COG0477	Major facilitator Superfamily
OCX50_RS18395	COG2985	domain, Protein
OCX50_RS18395	COG0569	domain protein
OCX50_RS18400	COG1272	protein, Hemolysin III
OCX50_RS18405	COG0076	glutamate decarboxylase activity
OCX50_RS18410	COG2917	probably involved in intracellular septation
OCX50_RS18415	COG2350	Protein conserved in bacteria
OCX50_RS18425	COG1555	photosystem II stabilization
OCX50_RS18430	COG1210	Utp--glucose-1-phosphate uridylyltransferase
OCX50_RS18435	COG3104	oligopeptide transport
OCX50_RS18440	COG0745	RESPONSE REGULATOR receiver
OCX50_RS18475	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS18490	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
OCX50_RS18500	COG1280	lysine exporter protein (LysE YggA)
OCX50_RS18550	COG2205	protein histidine kinase activity
OCX50_RS18555	COG0745	RESPONSE REGULATOR receiver
OCX50_RS18560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS18565	COG0577	efflux transmembrane transporter activity
OCX50_RS18565	COG1136	(ABC) transporter
OCX50_RS18595	COG0316	Belongs to the HesB IscA family
OCX50_RS18605	COG0038	chloride channel
OCX50_RS18610	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
OCX50_RS18625	COG3385	transposase activity
OCX50_RS18630	COG0671	phosphoesterase, PA-phosphatase related
OCX50_RS18640	COG0583	DNA-binding transcription factor activity
OCX50_RS18645	COG2076	Multidrug Resistance protein
OCX50_RS18655	COG0346	lactoylglutathione lyase activity
OCX50_RS18660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
OCX50_RS18665	COG1643	Atp-dependent helicase
OCX50_RS18675	COG1489	DNA binding
OCX50_RS18680	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
OCX50_RS18685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
OCX50_RS18695	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
OCX50_RS18700	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
OCX50_RS18705	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
OCX50_RS18715	COG0842	Transport permease protein
OCX50_RS18720	COG1131	(ABC) transporter
OCX50_RS18735	COG0163	prenyltransferase activity
OCX50_RS18740	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
OCX50_RS18745	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
OCX50_RS18760	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
OCX50_RS18775	COG1136	(ABC) transporter
OCX50_RS18820	COG3385	transposase activity
OCX50_RS18850	COG0529	Catalyzes the synthesis of activated sulfate
OCX50_RS18855	COG3273	potassium ion transport
OCX50_RS18855	COG0471	metal ion transport
OCX50_RS18860	COG2895	sulfate adenylyltransferase (ATP) activity
OCX50_RS18865	COG0175	sulfate reduction
OCX50_RS18870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCX50_RS18870	COG1648	precorrin-2 dehydrogenase activity
OCX50_RS18875	COG0330	HflC and HflK could
OCX50_RS18880	COG1585	Membrane protein implicated in regulation of membrane protease activity
OCX50_RS18890	COG0673	inositol 2-dehydrogenase activity
OCX50_RS18900	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
OCX50_RS18905	COG0635	Involved in the biosynthesis of porphyrin-containing compound
OCX50_RS18910	COG3036	rescue of stalled ribosome
OCX50_RS18925	COG0138	bifunctional purine biosynthesis protein purh
OCX50_RS18960	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
OCX50_RS18965	COG0358	DNA primase activity
OCX50_RS18970	COG1610	YqeY-like protein
OCX50_RS18975	COG0828	Belongs to the bacterial ribosomal protein bS21 family
OCX50_RS18980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
OCX50_RS18990	COG1388	LysM domain
OCX50_RS18990	COG4942	peptidase
OCX50_RS18995	COG1238	metal cluster binding
OCX50_RS19000	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
OCX50_RS19005	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
OCX50_RS19010	COG0585	pseudouridine synthase activity
OCX50_RS19020	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
OCX50_RS19025	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
OCX50_RS19030	COG0148	phosphopyruvate hydratase activity
OCX50_RS19035	COG0504	CTP synthase activity
OCX50_RS19040	COG3956	TIGRFAM MazG family protein
OCX50_RS19045	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
OCX50_RS19050	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCX50_RS19060	COG4807	Protein conserved in bacteria
OCX50_RS19065	COG3023	N-Acetylmuramoyl-L-alanine amidase
OCX50_RS19070	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
OCX50_RS19075	COG1381	Involved in DNA repair and RecF pathway recombination
OCX50_RS19085	COG0571	ribonuclease III activity
OCX50_RS19090	COG0681	Belongs to the peptidase S26 family
OCX50_RS19095	COG0481	GTPase activity
OCX50_RS19110	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
OCX50_RS19115	COG1595	DNA-templated transcription, initiation
OCX50_RS19120	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
OCX50_RS19130	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
OCX50_RS19140	COG0583	DNA-binding transcription factor activity
OCX50_RS19170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
OCX50_RS19180	COG0126	phosphoglycerate kinase activity
OCX50_RS19185	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
OCX50_RS19190	COG1940	carbohydrate kinase activity
OCX50_RS19195	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
OCX50_RS19205	COG4991	sh3 domain protein
OCX50_RS19210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
OCX50_RS19225	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
OCX50_RS19230	COG1028	Short-chain dehydrogenase reductase Sdr
OCX50_RS19240	COG1505	serine-type exopeptidase activity
OCX50_RS19245	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
OCX50_RS19250	COG0765	amino acid transport
OCX50_RS19255	COG0765	amino acid transport
OCX50_RS19260	COG1126	abc transporter atp-binding protein
OCX50_RS19265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
OCX50_RS19270	COG3174	membrane
OCX50_RS19275	COG0110	maltose O-acetyltransferase activity
OCX50_RS19305	COG1942	4-Oxalocrotonate Tautomerase
OCX50_RS19315	COG0583	DNA-binding transcription factor activity
OCX50_RS19320	COG0165	Argininosuccinate lyase
OCX50_RS19325	COG0137	argininosuccinate synthase activity
OCX50_RS19335	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
OCX50_RS19340	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
OCX50_RS19350	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
OCX50_RS19355	COG5002	protein histidine kinase activity
OCX50_RS19355	COG5001	Diguanylate cyclase
OCX50_RS19355	COG3447	MASE1 domain protein
OCX50_RS19360	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
OCX50_RS19395	COG0583	DNA-binding transcription factor activity
OCX50_RS19400	COG1380	Effector of murein hydrolase LrgA
OCX50_RS19405	COG1346	cytolysis
OCX50_RS19410	COG0460	homoserine dehydrogenase
OCX50_RS19410	COG0527	aspartate kinase activity
OCX50_RS19415	COG0626	cystathionine gamma-synthase activity
OCX50_RS19430	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
OCX50_RS19435	COG0814	amino acid
OCX50_RS19440	COG1218	3'(2'),5'-bisphosphate nucleotidase
OCX50_RS19445	COG0494	nUDIX hydrolase
OCX50_RS19450	COG1011	Hydrolase
OCX50_RS19455	COG1902	pentaerythritol trinitrate reductase activity
OCX50_RS19465	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
OCX50_RS19480	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
OCX50_RS19490	COG3156	type II secretion system protein K
OCX50_RS19500	COG4795	General secretion pathway protein
OCX50_RS19505	COG2165	general secretion pathway protein
OCX50_RS19515	COG2165	general secretion pathway protein
OCX50_RS19520	COG1459	type II secretion system
OCX50_RS19525	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
OCX50_RS19535	COG3031	protein transport across the cell outer membrane
OCX50_RS19545	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
OCX50_RS19550	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
OCX50_RS19565	COG0456	acetyltransferase
OCX50_RS19570	COG3133	Outer membrane lipoprotein
OCX50_RS19575	COG3025	triphosphatase activity
OCX50_RS19580	COG1392	Phosphate transport regulator
OCX50_RS19585	COG0306	phosphate transporter
OCX50_RS19590	COG0617	tRNA 3'-terminal CCA addition
OCX50_RS19595	COG3267	Type II secretory pathway component ExeA
OCX50_RS19595	COG3409	Peptidoglycan-binding domain 1 protein
OCX50_RS19605	COG1194	a g-specific adenine glycosylase
OCX50_RS19610	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
OCX50_RS19625	COG3240	lipase activity
OCX50_RS19635	COG3009	Protein conserved in bacteria
OCX50_RS19640	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
OCX50_RS19640	COG3008	intermembrane lipid transfer
OCX50_RS19645	COG2995	paraquat-inducible protein a
OCX50_RS19655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
OCX50_RS19660	COG4251	negative regulation of phosphorylation
OCX50_RS19660	COG2203	Gaf domain
OCX50_RS19660	COG3706	GGDEF domain
OCX50_RS19660	COG5001	Diguanylate cyclase
OCX50_RS19665	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
OCX50_RS19670	COG2813	Specifically methylates the guanine in position
OCX50_RS19680	COG0297	glycogen (starch) synthase activity
OCX50_RS19720	COG1757	Na H antiporter
OCX50_RS19725	COG0583	DNA-binding transcription factor activity
OCX50_RS19730	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
OCX50_RS19735	COG3842	ATPase activity
OCX50_RS19740	COG1176	ABC-type spermidine putrescine transport system, permease component I
OCX50_RS19745	COG1177	transmembrane transport
OCX50_RS19750	COG1012	belongs to the aldehyde dehydrogenase family
OCX50_RS19755	COG0109	protoheme IX farnesyltransferase activity
OCX50_RS19785	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
OCX50_RS19795	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
OCX50_RS19795	COG1565	acr, cog1565
OCX50_RS19800	COG1444	tRNA N-acetyltransferase activity
OCX50_RS19820	COG1803	Methylglyoxal synthase
OCX50_RS19835	COG0252	asparaginase activity
OCX50_RS19855	COG1263	PTS System
OCX50_RS19855	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
OCX50_RS19860	COG0366	Alpha amylase catalytic
OCX50_RS19865	COG0110	maltose O-acetyltransferase activity
OCX50_RS19870	COG1522	sequence-specific DNA binding
OCX50_RS19905	COG3068	Protein conserved in bacteria
OCX50_RS19915	COG0739	heme binding
OCX50_RS19935	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
OCX50_RS19940	COG1121	(ABC) transporter
OCX50_RS19945	COG1108	ABC-type Mn2 Zn2 transport systems permease components
OCX50_RS19950	COG0583	DNA-binding transcription factor activity
OCX50_RS19960	COG1573	uracil-dna glycosylase
OCX50_RS19965	COG2962	Rard protein
OCX50_RS19970	COG2827	Endonuclease containing a URI domain
OCX50_RS19985	COG1842	Phage shock protein A
OCX50_RS19990	COG0204	Acyl-transferase
OCX50_RS20010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
OCX50_RS20020	COG0484	heat shock protein binding
OCX50_RS20065	COG3039	Transposase
OCX50_RS20090	COG1289	transmembrane transporter activity
OCX50_RS20095	COG1566	PFAM secretion protein HlyD family protein
OCX50_RS20110	COG1051	belongs to the nudix hydrolase family
OCX50_RS20115	COG3150	esterase
OCX50_RS20125	COG3151	Protein conserved in bacteria
OCX50_RS20130	COG0494	nUDIX hydrolase
OCX50_RS20135	COG1538	Outer membrane efflux protein
OCX50_RS20140	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
OCX50_RS20140	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
OCX50_RS20145	COG1560	Kdo2-lipid A biosynthetic process
OCX50_RS20165	COG3916	Acyl-homoserine-lactone synthase
OCX50_RS20175	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
OCX50_RS20180	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
OCX50_RS20180	COG2213	PTS system mannitol-specific
OCX50_RS20185	COG0246	Mannitol dehydrogenase
OCX50_RS20190	COG3722	fumarate hydratase activity
OCX50_RS20195	COG3263	regulation of cellular component size
OCX50_RS20230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
OCX50_RS20235	COG0513	Belongs to the DEAD box helicase family
OCX50_RS20255	COG1575	Belongs to the MenA family. Type 1 subfamily
OCX50_RS20260	COG1169	isochorismate synthase
OCX50_RS20265	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
OCX50_RS20270	COG0596	Alpha beta hydrolase
OCX50_RS20275	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
OCX50_RS20285	COG0318	PFAM AMP-dependent synthetase and ligase
OCX50_RS20290	COG3291	Pkd domain containing protein
OCX50_RS20295	COG2949	membrane
OCX50_RS20300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
OCX50_RS20310	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
OCX50_RS20340	COG2873	o-acetylhomoserine
OCX50_RS20350	COG1979	alcohol dehydrogenase
OCX50_RS20365	COG4221	oxidoreductase activity
OCX50_RS20385	COG1285	pathogenesis
OCX50_RS20400	COG1368	sulfuric ester hydrolase activity
OCX50_RS20405	COG1522	sequence-specific DNA binding
OCX50_RS20415	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
OCX50_RS20425	COG1546	Belongs to the CinA family
OCX50_RS20425	COG1058	Belongs to the CinA family
OCX50_RS20430	COG1988	membrane-bound metal-dependent
OCX50_RS20445	COG0561	phosphatase activity
OCX50_RS20450	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
OCX50_RS20460	COG1011	Hydrolase
OCX50_RS20475	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
OCX50_RS20480	COG0019	diaminopimelate decarboxylase activity
OCX50_RS20490	COG1965	Belongs to the frataxin family
OCX50_RS20495	COG0400	carboxylic ester hydrolase activity
OCX50_RS20500	COG3072	Adenylate cyclase
OCX50_RS20505	COG0181	hydroxymethylbilane synthase activity
OCX50_RS20515	COG2959	enzyme of heme biosynthesis
OCX50_RS20520	COG3071	HemY protein
OCX50_RS20535	COG0312	modulator of DNA gyrase
OCX50_RS20540	COG3028	Belongs to the UPF0307 family
OCX50_RS20550	COG2926	Belongs to the UPF0265 family
OCX50_RS20585	COG1396	sequence-specific DNA binding
OCX50_RS20590	COG3135	benzoate transporter
OCX50_RS20620	COG3047	cAMP biosynthetic process
OCX50_RS20635	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
OCX50_RS20640	COG2197	response regulator
OCX50_RS20675	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OCX50_RS20710	COG1396	sequence-specific DNA binding
OCX50_RS20745	COG1278	Cold shock
OCX50_RS20775	COG3706	GGDEF domain
OCX50_RS20780	COG0347	Belongs to the P(II) protein family
OCX50_RS20785	COG0004	ammonium transporteR
OCX50_RS20795	COG0346	lactoylglutathione lyase activity
OCX50_RS20800	COG3385	transposase activity
OCX50_RS20815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
OCX50_RS20820	COG1074	ATP-dependent DNA helicase activity
OCX50_RS20825	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
OCX50_RS20830	COG2259	Doxx family
OCX50_RS20835	COG1741	Belongs to the pirin family
OCX50_RS20845	COG0583	DNA-binding transcription factor activity
OCX50_RS20870	COG1175	transmembrane transport
OCX50_RS20910	COG0456	acetyltransferase
OCX50_RS20915	COG0753	catalase activity
OCX50_RS20935	COG0494	nUDIX hydrolase
OCX50_RS20940	COG0628	permease
OCX50_RS20950	COG2957	Belongs to the agmatine deiminase family
OCX50_RS20965	COG2957	Belongs to the agmatine deiminase family
OCX50_RS20970	COG0583	DNA-binding transcription factor activity
OCX50_RS20985	COG1461	Dihydroxyacetone kinase
OCX50_RS20990	COG2376	Dihydroxyacetone kinase
OCX50_RS20995	COG2252	PERMEase
OCX50_RS21000	COG3335	DDE superfamily endonuclease
OCX50_RS21005	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
OCX50_RS21040	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
OCX50_RS21045	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCX50_RS21050	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
OCX50_RS21055	COG0049	tRNA binding
OCX50_RS21060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
OCX50_RS21065	COG2168	tRNA wobble position uridine thiolation
OCX50_RS21075	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
OCX50_RS21080	COG0251	oxidation-reduction process
OCX50_RS21085	COG2964	Protein conserved in bacteria
OCX50_RS21090	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
OCX50_RS21095	COG0085	RNA polymerase activity
OCX50_RS21100	COG0222	ribosome binding
OCX50_RS21105	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
OCX50_RS21110	COG0081	regulation of translation
OCX50_RS21115	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
OCX50_RS21120	COG0250	Participates in transcription elongation, termination and antitermination
OCX50_RS21135	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
OCX50_RS21160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
OCX50_RS21165	COG0569	domain protein
OCX50_RS21170	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCX50_RS21175	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
OCX50_RS21180	COG3005	denitrification pathway
OCX50_RS21185	COG0243	molybdopterin cofactor binding
OCX50_RS21220	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
OCX50_RS21230	COG2204	response regulator
OCX50_RS21240	COG2205	protein histidine kinase activity
OCX50_RS21260	COG0517	IMP dehydrogenase activity
OCX50_RS21260	COG0516	GMP reductase activity
OCX50_RS21270	COG1522	sequence-specific DNA binding
OCX50_RS21275	COG2502	aspartate--ammonia ligase
OCX50_RS21290	COG0583	DNA-binding transcription factor activity
OCX50_RS21295	COG0542	response to heat
OCX50_RS21305	COG0564	pseudouridine synthase activity
OCX50_RS21310	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
OCX50_RS21315	COG3681	Belongs to the UPF0597 family
OCX50_RS21320	COG2964	Protein conserved in bacteria
OCX50_RS21325	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
OCX50_RS21330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
OCX50_RS21335	COG1979	alcohol dehydrogenase
OCX50_RS21340	COG2207	Transcriptional regulator
OCX50_RS21345	COG3040	lipid binding
OCX50_RS21365	COG0583	DNA-binding transcription factor activity
OCX50_RS21385	COG0540	Belongs to the ATCase OTCase family
OCX50_RS21390	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
OCX50_RS21395	COG1438	arginine binding
OCX50_RS21400	COG1288	antiporter activity
OCX50_RS21405	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
OCX50_RS21450	COG3250	beta-galactosidase activity
OCX50_RS21460	COG1609	Transcriptional regulator
OCX50_RS21465	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
OCX50_RS21475	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
OCX50_RS21480	COG2017	converts alpha-aldose to the beta-anomer
OCX50_RS21485	COG0667	Aldo Keto reductase
OCX50_RS21490	COG1968	undecaprenyl-diphosphatase activity
OCX50_RS21495	COG3806	Anti-sigma factor
OCX50_RS21500	COG1595	DNA-templated transcription, initiation
OCX50_RS21520	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
OCX50_RS21525	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
OCX50_RS21530	COG0477	Major facilitator Superfamily
OCX50_RS21545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
OCX50_RS21550	COG1131	(ABC) transporter
OCX50_RS21555	COG0842	Transport permease protein
OCX50_RS21560	COG0842	Transport permease protein
OCX50_RS21565	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
OCX50_RS21575	COG2116	formate transmembrane transporter activity
OCX50_RS21580	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
OCX50_RS21580	COG1648	precorrin-2 dehydrogenase activity
OCX50_RS21585	COG2239	Acts as a magnesium transporter
OCX50_RS21590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
OCX50_RS21595	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
OCX50_RS21605	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
OCX50_RS21615	COG0514	ATP-dependent DNA helicase (RecQ)
OCX50_RS21620	COG2050	protein possibly involved in aromatic compounds catabolism
OCX50_RS21635	COG2258	MOSC domain
OCX50_RS21640	COG1177	transmembrane transport
OCX50_RS21645	COG1176	ABC-type spermidine putrescine transport system, permease component I
OCX50_RS21650	COG3842	ATPase activity
OCX50_RS21670	COG0174	glutamine synthetase
OCX50_RS21690	COG3045	CreA protein
OCX50_RS21695	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
OCX50_RS21700	COG0443	Heat shock 70 kDa protein
OCX50_RS21715	COG0366	Alpha amylase catalytic
OCX50_RS21730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
OCX50_RS21735	COG0745	RESPONSE REGULATOR receiver
OCX50_RS21745	COG2205	protein histidine kinase activity
OCX50_RS21755	COG0281	malic enzyme
OCX50_RS21760	COG0702	epimerase
OCX50_RS21765	COG0254	rRNA binding
OCX50_RS21770	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
OCX50_RS21795	COG0129	dihydroxy-acid dehydratase activity
OCX50_RS21805	COG3978	acetolactate synthase activity
OCX50_RS21815	COG0606	chelatase, subunit chli
OCX50_RS21820	COG0204	Acyl-transferase
OCX50_RS21825	COG0204	Acyl-transferase
OCX50_RS21830	COG1683	Conserved Protein
OCX50_RS21840	COG1335	isochorismatase
OCX50_RS21850	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
OCX50_RS21855	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
OCX50_RS21865	COG3084	Protein conserved in bacteria
OCX50_RS21870	COG2203	Gaf domain
OCX50_RS21870	COG3706	GGDEF domain
OCX50_RS21870	COG4251	negative regulation of phosphorylation
OCX50_RS21870	COG5001	Diguanylate cyclase
OCX50_RS21885	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
OCX50_RS21890	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
OCX50_RS21895	COG1561	YicC-like family, N-terminal region
OCX50_RS21905	COG1519	Transferase
OCX50_RS21910	COG0859	PFAM glycosyl transferase family 9
OCX50_RS21915	COG0463	Glycosyl transferase, family 2
OCX50_RS21920	COG0859	PFAM glycosyl transferase family 9
OCX50_RS21925	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
OCX50_RS21930	COG2990	Protein conserved in bacteria
OCX50_RS21935	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
OCX50_RS21945	COG0267	Belongs to the bacterial ribosomal protein bL33 family
OCX50_RS21950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
OCX50_RS21955	COG2003	Belongs to the UPF0758 family
OCX50_RS21960	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
OCX50_RS21965	COG0756	dUTP diphosphatase activity
OCX50_RS21970	COG1309	transcriptional regulator
OCX50_RS21980	COG0668	transmembrane transport
OCX50_RS21990	COG0166	Belongs to the GPI family
OCX50_RS22000	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
OCX50_RS22005	COG0583	DNA-binding transcription factor activity
OCX50_RS22015	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
OCX50_RS22015	COG1042	CoA-binding domain protein
OCX50_RS22015	COG0045	succinate-CoA ligase (ADP-forming) activity
OCX50_RS22040	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
OCX50_RS22045	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
OCX50_RS22050	COG1739	Uncharacterized protein family UPF0029
OCX50_RS22055	COG0006	proline dipeptidase activity
OCX50_RS22060	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
OCX50_RS22065	COG1250	3-hydroxyacyl-CoA dehydrogenase
OCX50_RS22065	COG1024	Enoyl-CoA hydratase
OCX50_RS22070	COG0183	Belongs to the thiolase family
OCX50_RS22110	COG0425	Belongs to the sulfur carrier protein TusA family
OCX50_RS22115	COG0251	oxidation-reduction process
OCX50_RS22135	COG2885	chlorophyll binding
OCX50_RS22145	COG1335	isochorismatase
OCX50_RS22150	COG2818	Glycosylase
OCX50_RS22155	COG0752	glycyl-tRNA synthetase alpha subunit
OCX50_RS22160	COG0751	glycine-tRNA ligase activity
OCX50_RS22165	COG3039	Transposase
OCX50_RS22185	COG5001	Diguanylate cyclase
OCX50_RS22185	COG4251	negative regulation of phosphorylation
OCX50_RS22185	COG3706	GGDEF domain
OCX50_RS22185	COG2203	Gaf domain
OCX50_RS22205	COG0814	amino acid
OCX50_RS22210	COG0814	amino acid
OCX50_RS22215	COG3033	Beta-eliminating lyase
OCX50_RS22230	COG0348	domain, Protein
OCX50_RS22240	COG0446	pyridine nucleotide-disulphide oxidoreductase
OCX50_RS22245	COG1773	rubredoxin
OCX50_RS22245	COG0426	domain, Protein
OCX50_RS22250	COG3604	Transcriptional regulator
OCX50_RS22255	COG1609	Transcriptional regulator
OCX50_RS22295	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
OCX50_RS22315	COG2960	long-chain fatty acid transporting porin activity
OCX50_RS22325	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
OCX50_RS22340	COG3118	belongs to the thioredoxin family
OCX50_RS22345	COG0513	Belongs to the DEAD box helicase family
OCX50_RS22350	COG0248	Ppx GppA phosphatase
OCX50_RS22360	COG0742	ribosomal rna small subunit methyltransferase
OCX50_RS22380	COG0084	hydrolase, TatD family'
OCX50_RS22385	COG0805	protein transport
OCX50_RS22390	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCX50_RS22395	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
OCX50_RS22400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
OCX50_RS22405	COG3165	ubiquinone biosynthetic process from chorismate
OCX50_RS22415	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
OCX50_RS22420	COG0402	S-adenosylhomocysteine deaminase activity
OCX50_RS22460	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
OCX50_RS22465	COG0848	biopolymer transport protein
OCX50_RS22470	COG0811	peptide transport
OCX50_RS22475	COG0811	peptide transport
OCX50_RS22485	COG2771	luxR family
OCX50_RS22490	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
OCX50_RS22495	COG1349	DNA-binding transcription factor activity
OCX50_RS22500	COG0745	RESPONSE REGULATOR receiver
OCX50_RS22505	COG2205	protein histidine kinase activity
OCX50_RS22520	COG4452	Inner membrane protein CreD
OCX50_RS22525	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
OCX50_RS22530	COG0355	proton-transporting ATP synthase activity, rotational mechanism
OCX50_RS22535	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
OCX50_RS22540	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
OCX50_RS22545	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
OCX50_RS22550	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
OCX50_RS22555	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
OCX50_RS22565	COG0356	it plays a direct role in the translocation of protons across the membrane
OCX50_RS22575	COG1475	DNA binding
OCX50_RS22580	COG1192	Involved in chromosome partitioning
OCX50_RS22585	COG0357	Ribosomal RNA small subunit methyltransferase G
OCX50_RS22590	COG0445	tRNA wobble uridine modification
OCX50_RS22595	COG0716	FMN binding
OCX50_RS22600	COG4774	siderophore transport
OCX50_RS22605	COG4615	Cyclic peptide transporter
OCX50_RS22610	COG1120	ATPase activity
OCX50_RS22615	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
OCX50_RS22625	COG3550	peptidyl-serine autophosphorylation
OCX50_RS22650	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
OCX50_RS22655	COG0706	membrane insertase activity
OCX50_RS22660	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
OCX50_RS22665	COG0594	ribonuclease P activity
OCX50_RS22670	COG0230	Belongs to the bacterial ribosomal protein bL34 family
OCX50_RS22675	COG1126	abc transporter atp-binding protein
OCX50_RS22810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS22940	COG0789	Transcriptional regulator
OCX50_RS22990	COG5002	protein histidine kinase activity
OCX50_RS22990	COG2176	DNA-directed DNA polymerase activity
OCX50_RS23055	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS23135	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
OCX50_RS23150	COG1192	Involved in chromosome partitioning
OCX50_RS23160	COG3335	DDE superfamily endonuclease
OCX50_RS23220	COG0489	protein tyrosine kinase activity
OCX50_RS23245	COG3039	Transposase
OCX50_RS23285	COG3093	addiction module antidote protein HigA