locus-tag	class	description
C0708_RS00120	COG4584	PFAM Integrase catalytic
C0708_RS00125	COG1484	DNA-dependent DNA replication
C0708_RS00135	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0708_RS00140	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0708_RS00160	COG0668	transmembrane transport
C0708_RS00170	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0708_RS00180	COG0789	Transcriptional regulator
C0708_RS00235	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C0708_RS00245	COG0488	(ABC) transporter
C0708_RS00250	COG0516	GMP reductase activity
C0708_RS00250	COG0517	IMP dehydrogenase activity
C0708_RS00260	COG0675	Transposase, IS605 OrfB family
C0708_RS00270	COG0835	chemotaxis
C0708_RS00270	COG0784	Response regulator, receiver
C0708_RS00275	COG2755	lipolytic protein G-D-S-L family
C0708_RS00280	COG4181	ATPase activity
C0708_RS00285	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C0708_RS00290	COG1090	epimerase
C0708_RS00295	COG2200	EAL domain
C0708_RS00300	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0708_RS00310	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C0708_RS00315	COG3171	Protein conserved in bacteria
C0708_RS00320	COG2066	Belongs to the glutaminase family
C0708_RS00325	COG2897	thiosulfate sulfurtransferase activity
C0708_RS00360	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C0708_RS00365	COG5001	Diguanylate cyclase
C0708_RS00365	COG3300	MHYT domain
C0708_RS00385	COG4628	conserved protein (DUF2132)
C0708_RS00390	COG0688	phosphatidylethanolamine metabolic process
C0708_RS00395	COG1162	GTPase activity
C0708_RS00400	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C0708_RS00440	COG1278	Cold shock
C0708_RS00450	COG0840	transmembrane signaling receptor activity
C0708_RS00455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0708_RS00460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0708_RS00465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0708_RS00470	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0708_RS00520	COG0848	biopolymer transport protein
C0708_RS00525	COG0811	peptide transport
C0708_RS00530	COG0811	peptide transport
C0708_RS00540	COG4206	TonB-dependent receptor
C0708_RS00550	COG4174	ABC transporter (Permease)
C0708_RS00555	COG4239	(ABC) transporter, permease
C0708_RS00570	COG4608	Belongs to the ABC transporter superfamily
C0708_RS00590	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C0708_RS00595	COG1073	alpha beta
C0708_RS00610	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C0708_RS00635	COG0243	molybdopterin cofactor binding
C0708_RS00650	COG1116	anion transmembrane transporter activity
C0708_RS00650	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C0708_RS00655	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C0708_RS00670	COG2146	nitrite reductase [NAD(P)H] activity
C0708_RS00670	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0708_RS00680	COG2313	pseudouridylate synthase activity
C0708_RS00700	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0708_RS00710	COG2966	Psort location CytoplasmicMembrane, score
C0708_RS00715	COG3610	response to peptide
C0708_RS00725	COG4175	Glycine betaine
C0708_RS00730	COG4176	ABC-type proline glycine betaine transport system permease component
C0708_RS00735	COG2113	Glycine betaine
C0708_RS00740	COG0175	sulfate reduction
C0708_RS00745	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0708_RS00750	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C0708_RS00755	COG0384	phenazine biosynthesis protein PhzF
C0708_RS00760	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C0708_RS00785	COG0786	glutamate:sodium symporter activity
C0708_RS00790	COG0252	asparaginase activity
C0708_RS00795	COG3139	Protein of unknown function (DUF1315)
C0708_RS00820	COG0616	signal peptide processing
C0708_RS00830	COG0778	Nitroreductase
C0708_RS00840	COG0110	maltose O-acetyltransferase activity
C0708_RS00845	COG2264	protein methyltransferase activity
C0708_RS00850	COG0604	alcohol dehydrogenase
C0708_RS00855	COG0583	DNA-binding transcription factor activity
C0708_RS00865	COG4145	pantothenate transmembrane transporter activity
C0708_RS00870	COG3924	membrane
C0708_RS00875	COG0439	Biotin carboxylase
C0708_RS00880	COG0511	ligase activity, forming carbon-carbon bonds
C0708_RS00885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C0708_RS00890	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0708_RS00905	COG3381	protein complex oligomerization
C0708_RS00915	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C0708_RS00925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C0708_RS00930	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0708_RS00930	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C0708_RS00945	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C0708_RS00950	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0708_RS00955	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C0708_RS00960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C0708_RS00965	COG4172	Belongs to the ABC transporter superfamily
C0708_RS00975	COG0601	transmembrane transport
C0708_RS00980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0708_RS00990	COG0142	geranyltranstransferase activity
C0708_RS00995	COG1722	exodeoxyribonuclease VII activity
C0708_RS01000	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0708_RS01005	COG1360	Flagellar Motor Protein
C0708_RS01020	COG1534	Rna-binding protein
C0708_RS01025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C0708_RS01035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C0708_RS01040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0708_RS01045	COG0149	triose-phosphate isomerase activity
C0708_RS01050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C0708_RS01065	COG0779	Required for maturation of 30S ribosomal subunits
C0708_RS01070	COG0195	Participates in both transcription termination and antitermination
C0708_RS01075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C0708_RS01080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C0708_RS01085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C0708_RS01090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C0708_RS01095	COG1185	polyribonucleotide nucleotidyltransferase activity
C0708_RS01100	COG2211	Major facilitator Superfamily
C0708_RS01105	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C0708_RS01110	COG1422	Protein of unknown function (DUF1090)
C0708_RS01125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0708_RS01130	COG0826	peptidase U32
C0708_RS01145	COG0312	modulator of DNA gyrase
C0708_RS01155	COG0312	modulator of DNA gyrase
C0708_RS01165	COG4974	Belongs to the 'phage' integrase family
C0708_RS01170	COG1970	mechanosensitive ion channel activity
C0708_RS01195	COG0789	Transcriptional regulator
C0708_RS01210	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C0708_RS01220	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C0708_RS01235	COG2921	Belongs to the UPF0250 family
C0708_RS01245	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C0708_RS01250	COG2951	lytic endotransglycosylase activity
C0708_RS01265	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C0708_RS01270	COG0799	negative regulation of ribosome biogenesis
C0708_RS01275	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C0708_RS01290	COG0495	leucyl-tRNA aminoacylation
C0708_RS01295	COG2888	peptidyl-tyrosine sulfation
C0708_RS01300	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C0708_RS01305	COG4535	Mg2 and Co2 transporter CorC
C0708_RS01310	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C0708_RS01315	COG1702	phosphate starvation-inducible protein PhoH
C0708_RS01350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0708_RS01375	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0708_RS01390	COG1464	Belongs to the NlpA lipoprotein family
C0708_RS01400	COG2011	ABC-type metal ion transport system permease component
C0708_RS01405	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C0708_RS01415	COG0516	GMP reductase activity
C0708_RS01420	COG4067	protein conserved in archaea
C0708_RS01420	COG0189	ligase activity
C0708_RS01440	COG0300	oxidoreductase activity
C0708_RS01460	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C0708_RS01480	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C0708_RS01485	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C0708_RS01490	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C0708_RS01495	COG1053	succinate dehydrogenase
C0708_RS01505	COG0584	glycerophosphoryl diester phosphodiesterase
C0708_RS01510	COG3264	Mechanosensitive ion channel
C0708_RS01510	COG1511	domain protein
C0708_RS01520	COG0739	heme binding
C0708_RS01535	COG0583	DNA-binding transcription factor activity
C0708_RS01585	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C0708_RS01590	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C0708_RS01600	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C0708_RS01605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C0708_RS01610	COG0546	phosphoglycolate phosphatase activity
C0708_RS01615	COG0180	Tryptophanyl-tRNA synthetase
C0708_RS01630	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C0708_RS01640	COG1012	belongs to the aldehyde dehydrogenase family
C0708_RS01655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0708_RS01670	COG0657	acetylesterase activity
C0708_RS01680	COG0471	metal ion transport
C0708_RS01680	COG0490	domain, Protein
C0708_RS01725	COG0012	GTP binding
C0708_RS01730	COG0193	aminoacyl-tRNA hydrolase activity
C0708_RS01735	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C0708_RS01745	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C0708_RS01750	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C0708_RS01755	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C0708_RS01760	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C0708_RS01765	COG2890	protein-(glutamine-N5) methyltransferase activity
C0708_RS01780	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C0708_RS01785	COG1301	dicarboxylic acid transport
C0708_RS01795	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C0708_RS01810	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C0708_RS01815	COG1115	amino acid carrier protein
C0708_RS01845	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C0708_RS01855	COG0189	ligase activity
C0708_RS01860	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C0708_RS01870	COG3091	SprT-like family
C0708_RS01880	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C0708_RS01895	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C0708_RS01900	COG0739	heme binding
C0708_RS01905	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C0708_RS01910	COG3408	Glycogen debranching enzyme
C0708_RS01910	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C0708_RS01920	COG1881	PFAM PEBP family protein
C0708_RS01925	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C0708_RS01930	COG0583	DNA-binding transcription factor activity
C0708_RS01940	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C0708_RS01950	COG0583	DNA-binding transcription factor activity
C0708_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
C0708_RS01960	COG0616	signal peptide processing
C0708_RS01965	COG3724	N-succinylarginine dihydrolase activity
C0708_RS01980	COG0840	transmembrane signaling receptor activity
C0708_RS01990	COG2971	BadF BadG BcrA BcrD
C0708_RS02000	COG4608	Belongs to the ABC transporter superfamily
C0708_RS02010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0708_RS02035	COG0640	Transcriptional regulator
C0708_RS02040	COG0798	PFAM Bile acid sodium symporter
C0708_RS02045	COG1393	Belongs to the ArsC family
C0708_RS02055	COG1677	Flagellar hook-basal body complex protein FliE
C0708_RS02065	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C0708_RS02120	COG1684	flagellar biosynthetic protein fliR
C0708_RS02155	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C0708_RS02160	COG2198	Histidine kinase
C0708_RS02160	COG0784	Response regulator, receiver
C0708_RS02160	COG0643	Histidine kinase
C0708_RS02165	COG2201	protein-glutamate methylesterase activity
C0708_RS02175	COG1360	Flagellar Motor Protein
C0708_RS02180	COG1192	Involved in chromosome partitioning
C0708_RS02190	COG0835	chemotaxis
C0708_RS02205	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0708_RS02210	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0708_RS02215	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C0708_RS02220	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C0708_RS02230	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0708_RS02240	COG0457	Tetratricopeptide repeat
C0708_RS02260	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C0708_RS02265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0708_RS02265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0708_RS02280	COG0259	pyridoxamine-phosphate oxidase activity
C0708_RS02310	COG3153	acetyltransferase
C0708_RS02325	COG0800	Aldolase
C0708_RS02330	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0708_RS02355	COG3311	Transcriptional regulator
C0708_RS02365	COG2916	Histone family protein nucleoid-structuring protein H-NS
C0708_RS02420	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
C0708_RS02450	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C0708_RS02495	COG5642	Protein of unknown function (DUF2384)
C0708_RS02510	COG0582	viral genome integration into host DNA
C0708_RS02520	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C0708_RS02525	COG2867	negative regulation of translational initiation
C0708_RS02535	COG0702	epimerase
C0708_RS02540	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0708_RS02545	COG1454	alcohol dehydrogenase
C0708_RS02560	COG1957	nucleoside hydrolase
C0708_RS02585	COG1280	lysine exporter protein (LysE YggA)
C0708_RS02595	COG3263	regulation of cellular component size
C0708_RS02605	COG1876	peptidase activity
C0708_RS02610	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C0708_RS02615	COG1393	Belongs to the ArsC family
C0708_RS02625	COG3069	C4-dicarboxylate transmembrane transporter activity
C0708_RS02640	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C0708_RS02645	COG0017	Asparaginyl-tRNA synthetase
C0708_RS02665	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C0708_RS02675	COG1073	alpha beta
C0708_RS02675	COG2226	methyltransferase
C0708_RS02680	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C0708_RS02685	COG0501	Belongs to the peptidase M48B family
C0708_RS02705	COG2841	Protein conserved in bacteria
C0708_RS02750	COG1309	transcriptional regulator
C0708_RS02765	COG0791	NLP P60 protein
C0708_RS02770	COG0583	DNA-binding transcription factor activity
C0708_RS02790	COG0500	methyltransferase
C0708_RS02795	COG4106	trans-aconitate 2-methyltransferase activity
C0708_RS02800	COG1801	Protein of unknown function DUF72
C0708_RS02810	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C0708_RS02815	COG0217	transcriptional regulatory protein
C0708_RS02820	COG2194	sulfuric ester hydrolase activity
C0708_RS02825	COG1940	carbohydrate kinase activity
C0708_RS02825	COG1846	Transcriptional regulator
C0708_RS02830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0708_RS02835	COG0363	glucosamine-6-phosphate deaminase activity
C0708_RS02840	COG2190	(PTS) system
C0708_RS02840	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0708_RS02840	COG1263	PTS System
C0708_RS02850	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0708_RS02855	COG0735	belongs to the Fur family
C0708_RS02865	COG0716	FMN binding
C0708_RS02880	COG0596	Alpha beta hydrolase
C0708_RS02885	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C0708_RS02890	COG0033	Phosphoglucomutase
C0708_RS02900	COG1846	Transcriptional regulator
C0708_RS02905	COG2951	lytic endotransglycosylase activity
C0708_RS02910	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C0708_RS02935	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0708_RS02945	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0708_RS02960	COG2911	Protein conserved in bacteria
C0708_RS02975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C0708_RS02985	COG0741	lytic transglycosylase activity
C0708_RS03000	COG1607	acyl-coa hydrolase
C0708_RS03010	COG3021	interspecies interaction between organisms
C0708_RS03015	COG0741	lytic transglycosylase activity
C0708_RS03015	COG1388	LysM domain
C0708_RS03020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0708_RS03025	COG2226	methyltransferase
C0708_RS03030	COG0328	RNA-DNA hybrid ribonuclease activity
C0708_RS03075	COG2916	Histone family protein nucleoid-structuring protein H-NS
C0708_RS03090	COG5642	Protein of unknown function (DUF2384)
C0708_RS03095	COG2850	peptidyl-arginine hydroxylation
C0708_RS03130	COG1484	DNA-dependent DNA replication
C0708_RS03135	COG4584	PFAM Integrase catalytic
C0708_RS03145	COG0210	DNA helicase
C0708_RS03170	COG4974	Belongs to the 'phage' integrase family
C0708_RS03175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0708_RS03185	COG0784	Response regulator, receiver
C0708_RS03185	COG3437	response regulator, receiver
C0708_RS03190	COG1960	acyl-CoA dehydrogenase activity
C0708_RS03195	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C0708_RS03200	COG0121	glutamine amidotransferase
C0708_RS03210	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C0708_RS03235	COG2197	response regulator
C0708_RS03240	COG3850	Histidine kinase
C0708_RS03245	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C0708_RS03250	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0708_RS03250	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C0708_RS03260	COG0243	molybdopterin cofactor binding
C0708_RS03265	COG0437	4 iron, 4 sulfur cluster binding
C0708_RS03270	COG0348	domain, Protein
C0708_RS03280	COG3005	denitrification pathway
C0708_RS03285	COG0521	Mo-molybdopterin cofactor biosynthetic process
C0708_RS03290	COG0315	cyclic pyranopterin monophosphate synthase activity
C0708_RS03300	COG0314	molybdopterin synthase activity
C0708_RS03320	COG2267	carboxylic ester hydrolase activity
C0708_RS03325	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0708_RS03335	COG0302	gtp cyclohydrolase
C0708_RS03340	COG0840	transmembrane signaling receptor activity
C0708_RS03345	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C0708_RS03355	COG0583	DNA-binding transcription factor activity
C0708_RS03370	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C0708_RS03385	COG2195	Cleaves the N-terminal amino acid of tripeptides
C0708_RS03445	COG0675	Transposase, IS605 OrfB family
C0708_RS03455	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C0708_RS03460	COG1187	pseudouridine synthase activity
C0708_RS03475	COG0583	DNA-binding transcription factor activity
C0708_RS03495	COG2979	Protein of unknown function (DUF533)
C0708_RS03505	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0708_RS03510	COG1271	oxidase subunit
C0708_RS03515	COG1294	oxidase, subunit
C0708_RS03525	COG2814	Major facilitator Superfamily
C0708_RS03530	COG0656	L-ascorbic acid biosynthetic process
C0708_RS03550	COG0583	DNA-binding transcription factor activity
C0708_RS03555	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C0708_RS03560	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C0708_RS03565	COG2271	Major facilitator Superfamily
C0708_RS03570	COG1349	DNA-binding transcription factor activity
C0708_RS03585	COG0584	glycerophosphoryl diester phosphodiesterase
C0708_RS03590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0708_RS03595	COG1605	Chorismate mutase
C0708_RS03595	COG0287	Prephenate dehydrogenase
C0708_RS03605	COG3085	chromosome segregation
C0708_RS03610	COG4574	serine-type endopeptidase inhibitor activity
C0708_RS03635	COG4771	TonB-dependent receptor
C0708_RS03640	COG3083	sulfuric ester hydrolase activity
C0708_RS03645	COG3082	Protein of unknown function (DUF1414)
C0708_RS03660	COG1175	transmembrane transport
C0708_RS03665	COG3833	ABC-type maltose transport systems, permease component
C0708_RS03670	COG3842	ATPase activity
C0708_RS03680	COG0596	Alpha beta hydrolase
C0708_RS03695	COG0425	Belongs to the sulfur carrier protein TusA family
C0708_RS03700	COG4783	chaperone-mediated protein folding
C0708_RS03710	COG1393	Belongs to the ArsC family
C0708_RS03740	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C0708_RS03745	COG2431	L-lysine efflux transmembrane transporter activity
C0708_RS03755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0708_RS03765	COG4160	amino acid transport
C0708_RS03775	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C0708_RS03785	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0708_RS03795	COG4953	penicillin-binding protein 1C
C0708_RS03805	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0708_RS03805	COG0301	tRNA thio-modification
C0708_RS03825	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C0708_RS03875	COG4310	Domain of unknown function (DUF2172)
C0708_RS03890	COG2089	acid synthase
C0708_RS03900	COG1083	cytidylyl-transferase
C0708_RS03920	COG0318	PFAM AMP-dependent synthetase and ligase
C0708_RS03935	COG1216	Glycosyl transferase, family 2
C0708_RS03955	COG0438	transferase activity, transferring glycosyl groups
C0708_RS03975	COG0438	transferase activity, transferring glycosyl groups
C0708_RS03980	COG0297	glycogen (starch) synthase activity
C0708_RS04000	COG0529	Catalyzes the synthesis of activated sulfate
C0708_RS04010	COG3848	Pyruvate phosphate dikinase
C0708_RS04010	COG0574	Belongs to the PEP-utilizing enzyme family
C0708_RS04015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C0708_RS04015	COG0512	Glutamine amidotransferase of anthranilate synthase
C0708_RS04020	COG1213	nucleotidyl transferase
C0708_RS04025	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C0708_RS04030	COG1086	Polysaccharide biosynthesis protein
C0708_RS04035	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C0708_RS04045	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C0708_RS04085	COG0346	lactoylglutathione lyase activity
C0708_RS04090	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C0708_RS04100	COG4659	FMN binding
C0708_RS04115	COG2878	Part of a membrane complex involved in electron transport
C0708_RS04120	COG4657	Part of a membrane complex involved in electron transport
C0708_RS04125	COG0675	Transposase, IS605 OrfB family
C0708_RS04130	COG5433	transposase activity
C0708_RS04135	COG3039	Transposase
C0708_RS04180	COG1288	antiporter activity
C0708_RS04185	COG0436	Aminotransferase
C0708_RS04195	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C0708_RS04205	COG1061	Type III restriction enzyme res subunit
C0708_RS04210	COG1566	PFAM secretion protein HlyD family protein
C0708_RS04230	COG0675	Transposase, IS605 OrfB family
C0708_RS04240	COG1966	Carbon starvation protein
C0708_RS04245	COG3279	Response regulator of the LytR AlgR family
C0708_RS04250	COG3275	phosphorelay sensor kinase activity
C0708_RS04260	COG1012	belongs to the aldehyde dehydrogenase family
C0708_RS04260	COG1454	alcohol dehydrogenase
C0708_RS04265	COG2095	MarC family integral membrane protein
C0708_RS04275	COG0601	transmembrane transport
C0708_RS04280	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0708_RS04285	COG0444	Belongs to the ABC transporter superfamily
C0708_RS04295	COG0861	Integral membrane protein TerC family
C0708_RS04300	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0708_RS04310	COG1301	dicarboxylic acid transport
C0708_RS04330	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C0708_RS04345	COG0537	adenosine 5'-monophosphoramidase activity
C0708_RS04380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0708_RS04385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0708_RS04415	COG3150	esterase
C0708_RS04420	COG1252	NADH dehydrogenase
C0708_RS04425	COG0393	Putative heavy-metal-binding
C0708_RS04440	COG0527	aspartate kinase activity
C0708_RS04445	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C0708_RS04445	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0708_RS04475	COG0583	DNA-binding transcription factor activity
C0708_RS04480	COG1620	l-lactate permease
C0708_RS04485	COG0247	lactate metabolic process
C0708_RS04530	COG1136	(ABC) transporter
C0708_RS04575	COG0672	)-iron permease
C0708_RS04615	COG0675	Transposase, IS605 OrfB family
C0708_RS04670	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C0708_RS04675	COG0326	Molecular chaperone. Has ATPase activity
C0708_RS04680	COG0563	adenylate kinase activity
C0708_RS04685	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C0708_RS04690	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C0708_RS04695	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0708_RS04715	COG5001	Diguanylate cyclase
C0708_RS04715	COG3300	MHYT domain
C0708_RS04755	COG3433	isochorismatase activity
C0708_RS04755	COG1535	isochorismatase
C0708_RS04765	COG1028	Short-chain dehydrogenase reductase Sdr
C0708_RS04800	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0708_RS04805	COG4771	TonB-dependent receptor
C0708_RS04845	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C0708_RS04850	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C0708_RS04855	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0708_RS04860	COG3385	transposase activity
C0708_RS04865	COG0861	Integral membrane protein TerC family
C0708_RS04880	COG1022	Amp-dependent synthetase and ligase
C0708_RS04890	COG1346	cytolysis
C0708_RS04895	COG1380	Effector of murein hydrolase LrgA
C0708_RS04905	COG3385	transposase activity
C0708_RS04915	COG2925	Exonuclease
C0708_RS04970	COG5433	transposase activity
C0708_RS04985	COG1085	galactose-1-phosphate uridylyltransferase
C0708_RS04990	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0708_RS05000	COG4580	involved in the transport of maltose and maltodextrins
C0708_RS05045	COG2182	Extracellular solute-binding protein
C0708_RS05050	COG1175	transmembrane transport
C0708_RS05055	COG3833	ABC-type maltose transport systems, permease component
C0708_RS05060	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C0708_RS05065	COG1874	Beta-galactosidase
C0708_RS05070	COG1263	PTS System
C0708_RS05070	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0708_RS05080	COG0469	pyruvate kinase activity
C0708_RS05120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0708_RS05135	COG2160	L-arabinose isomerase activity
C0708_RS05145	COG1069	ribulokinase activity
C0708_RS05150	COG1879	ABC-type sugar transport system periplasmic component
C0708_RS05160	COG1172	Belongs to the binding-protein-dependent transport system permease family
C0708_RS05175	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0708_RS05180	COG0254	rRNA binding
C0708_RS05195	COG1451	nucleotide metabolic process
C0708_RS05210	COG3069	C4-dicarboxylate transmembrane transporter activity
C0708_RS05225	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0708_RS05245	COG2009	succinate dehydrogenase
C0708_RS05250	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C0708_RS05265	COG0567	Dehydrogenase, E1 component
C0708_RS05275	COG0045	succinate-CoA ligase (ADP-forming) activity
C0708_RS05280	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C0708_RS05290	COG2983	Belongs to the UPF0260 family
C0708_RS05295	COG1882	Formate acetyltransferase
C0708_RS05300	COG2116	formate transmembrane transporter activity
C0708_RS05305	COG1944	ATP diphosphatase activity
C0708_RS05320	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0708_RS05325	COG1278	Cold shock
C0708_RS05330	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C0708_RS05335	COG0542	response to heat
C0708_RS05340	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C0708_RS05345	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C0708_RS05350	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C0708_RS05355	COG3134	Outer membrane lipoprotein
C0708_RS05360	COG3706	GGDEF domain
C0708_RS05370	COG0492	ferredoxin-NADP+ reductase activity
C0708_RS05375	COG0686	Belongs to the AlaDH PNT family
C0708_RS05385	COG0531	amino acid
C0708_RS05385	COG1674	ftsk spoiiie
C0708_RS05395	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C0708_RS05400	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C0708_RS05405	COG1286	toxin biosynthetic process
C0708_RS05410	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C0708_RS05420	COG1263	PTS System
C0708_RS05420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0708_RS05435	COG0675	Transposase, IS605 OrfB family
C0708_RS05450	COG4172	Belongs to the ABC transporter superfamily
C0708_RS05460	COG4171	peptide transport system, permease
C0708_RS05475	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C0708_RS05480	COG1842	Phage shock protein A
C0708_RS05495	COG3106	COG3106 Predicted ATPase
C0708_RS05500	COG3768	UPF0283 membrane protein
C0708_RS05510	COG2154	pterin-4-alpha-carbinolamine dehydratase
C0708_RS05525	COG2199	diguanylate cyclase activity
C0708_RS05530	COG2885	chlorophyll binding
C0708_RS05560	COG0675	Transposase, IS605 OrfB family
C0708_RS05575	COG0517	IMP dehydrogenase activity
C0708_RS05575	COG0516	GMP reductase activity
C0708_RS05580	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0708_RS05580	COG0519	Catalyzes the synthesis of GMP from XMP
C0708_RS05590	COG0582	viral genome integration into host DNA
C0708_RS05675	COG0789	Transcriptional regulator
C0708_RS05725	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0708_RS05765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C0708_RS05865	COG4584	PFAM Integrase catalytic
C0708_RS05870	COG1484	DNA-dependent DNA replication
C0708_RS05895	COG1846	Transcriptional regulator
C0708_RS05915	COG2062	phosphohistidine phosphatase, SixA
C0708_RS05925	COG0697	spore germination
C0708_RS05940	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C0708_RS05945	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C0708_RS05955	COG4591	ABC-type transport system involved in lipoprotein release permease component
C0708_RS05960	COG1136	(ABC) transporter
C0708_RS05965	COG4591	ABC-type transport system involved in lipoprotein release permease component
C0708_RS05970	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C0708_RS05985	COG0544	peptidyl-prolyl cis-trans isomerase activity
C0708_RS05990	COG0740	serine-type endopeptidase activity
C0708_RS05995	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C0708_RS06000	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C0708_RS06005	COG0776	regulation of translation
C0708_RS06010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C0708_RS06015	COG0488	(ABC) transporter
C0708_RS06020	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C0708_RS06025	COG3162	membrane
C0708_RS06040	COG1024	Enoyl-CoA hydratase
C0708_RS06045	COG1115	amino acid carrier protein
C0708_RS06055	COG3228	Belongs to the MtfA family
C0708_RS06060	COG1584	GPR1 FUN34 yaaH family protein
C0708_RS06085	COG1024	Enoyl-CoA hydratase
C0708_RS06090	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C0708_RS06095	COG1960	acyl-CoA dehydrogenase activity
C0708_RS06110	COG1024	Enoyl-CoA hydratase
C0708_RS06115	COG1024	Enoyl-CoA hydratase
C0708_RS06135	COG0730	response to heat
C0708_RS06165	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C0708_RS06200	COG4584	PFAM Integrase catalytic
C0708_RS06205	COG1484	DNA-dependent DNA replication
C0708_RS06225	COG2003	Belongs to the UPF0758 family
C0708_RS06235	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C0708_RS06265	COG0583	DNA-binding transcription factor activity
C0708_RS06270	COG2072	flavoprotein involved in K transport
C0708_RS06305	COG2197	response regulator
C0708_RS06310	COG2205	protein histidine kinase activity
C0708_RS06310	COG0784	Response regulator, receiver
C0708_RS06315	COG1172	Belongs to the binding-protein-dependent transport system permease family
C0708_RS06320	COG1129	ABC transporter
C0708_RS06335	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C0708_RS06355	COG2723	6-phospho-beta-galactosidase activity
C0708_RS06365	COG0583	DNA-binding transcription factor activity
C0708_RS06380	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C0708_RS06385	COG0673	inositol 2-dehydrogenase activity
C0708_RS06390	COG0583	DNA-binding transcription factor activity
C0708_RS06400	COG1560	Kdo2-lipid A biosynthetic process
C0708_RS06405	COG1560	Kdo2-lipid A biosynthetic process
C0708_RS06450	COG0534	Mate efflux family protein
C0708_RS06460	COG0307	riboflavin synthase, alpha
C0708_RS06475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0708_RS06485	COG0697	spore germination
C0708_RS06490	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C0708_RS06515	COG2996	Protein conserved in bacteria
C0708_RS06535	COG3099	Belongs to the UPF0263 family
C0708_RS06540	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C0708_RS06545	COG2894	cell division
C0708_RS06550	COG0850	regulation of cytokinetic process
C0708_RS06555	COG3100	YcgL domain-containing protein
C0708_RS06570	COG1760	l-serine dehydratase
C0708_RS06580	COG1760	l-serine dehydratase
C0708_RS06585	COG3123	guanosine phosphorylase activity
C0708_RS06590	COG1301	dicarboxylic acid transport
C0708_RS06615	COG2067	long-chain fatty acid transport protein
C0708_RS06625	COG1595	DNA-templated transcription, initiation
C0708_RS06655	COG0714	Associated with various cellular activities
C0708_RS06660	COG0183	Belongs to the thiolase family
C0708_RS06665	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0708_RS06665	COG1024	Enoyl-CoA hydratase
C0708_RS06675	COG4681	YaeQ
C0708_RS06705	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C0708_RS06720	COG3134	Outer membrane lipoprotein
C0708_RS06725	COG0318	PFAM AMP-dependent synthetase and ligase
C0708_RS06730	COG2378	regulation of single-species biofilm formation
C0708_RS06740	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C0708_RS06740	COG0140	phosphoribosyl-ATP diphosphatase activity
C0708_RS06745	COG0107	imidazoleglycerol-phosphate synthase activity
C0708_RS06755	COG2199	diguanylate cyclase activity
C0708_RS06760	COG3437	response regulator, receiver
C0708_RS06765	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C0708_RS06770	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C0708_RS06775	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C0708_RS06775	COG0131	Imidazoleglycerol-phosphate dehydratase
C0708_RS06780	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C0708_RS06785	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C0708_RS06790	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C0708_RS06805	COG1214	PFAM Peptidase M22, glycoprotease
C0708_RS06815	COG0596	Alpha beta hydrolase
C0708_RS06850	COG2832	Protein of unknown function (DUF454)
C0708_RS06855	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C0708_RS06865	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C0708_RS06870	COG0583	DNA-binding transcription factor activity
C0708_RS06880	COG3314	Sporulation integral membrane protein YlbJ
C0708_RS06885	COG2197	response regulator
C0708_RS06890	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C0708_RS06890	COG0617	tRNA 3'-terminal CCA addition
C0708_RS06890	COG0517	IMP dehydrogenase activity
C0708_RS06895	COG1643	Atp-dependent helicase
C0708_RS06905	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C0708_RS06920	COG0675	Transposase, IS605 OrfB family
C0708_RS06935	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C0708_RS06940	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C0708_RS06945	COG0709	Synthesizes selenophosphate from selenide and ATP
C0708_RS06960	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C0708_RS06970	COG1254	Belongs to the acylphosphatase family
C0708_RS06980	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0708_RS06980	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0708_RS06990	COG0572	uridine kinase
C0708_RS06995	COG0717	Belongs to the dCTP deaminase family
C0708_RS07000	COG0306	phosphate transporter
C0708_RS07005	COG1530	ribonuclease E activity
C0708_RS07010	COG0564	pseudouridine synthase activity
C0708_RS07025	COG1399	metal-binding, possibly nucleic acid-binding protein
C0708_RS07030	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C0708_RS07035	COG0416	fatty acid biosynthetic process
C0708_RS07040	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0708_RS07050	COG1028	Short-chain dehydrogenase reductase Sdr
C0708_RS07055	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C0708_RS07060	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C0708_RS07065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C0708_RS07070	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C0708_RS07075	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C0708_RS07080	COG0470	DNA polymerase III
C0708_RS07085	COG0084	hydrolase, TatD family'
C0708_RS07100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0708_RS07100	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C0708_RS07110	COG2995	paraquat-inducible protein a
C0708_RS07125	COG3141	response to X-ray
C0708_RS07135	COG1067	ATP-dependent peptidase activity
C0708_RS07140	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C0708_RS07155	COG0488	(ABC) transporter
C0708_RS07165	COG0116	Belongs to the methyltransferase superfamily
C0708_RS07165	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C0708_RS07175	COG0167	dihydroorotate dehydrogenase activity
C0708_RS07180	COG2902	Dehydrogenase
C0708_RS07190	COG0308	aminopeptidase N
C0708_RS07200	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C0708_RS07205	COG1956	GAF domain-containing protein
C0708_RS07235	COG2010	Cytochrome c
C0708_RS07245	COG2217	Heavy metal translocating P-type atpase
C0708_RS07260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0708_RS07265	COG0589	response to stress
C0708_RS07270	COG0037	tRNA processing
C0708_RS07285	COG0675	Transposase, IS605 OrfB family
C0708_RS07295	COG0625	glutathione transferase activity
C0708_RS07300	COG1869	D-ribose catabolic process
C0708_RS07305	COG1129	ABC transporter
C0708_RS07310	COG1172	Belongs to the binding-protein-dependent transport system permease family
C0708_RS07315	COG1879	ABC-type sugar transport system periplasmic component
C0708_RS07320	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C0708_RS07325	COG1609	Transcriptional regulator
C0708_RS07335	COG0675	Transposase, IS605 OrfB family
C0708_RS07370	COG0776	regulation of translation
C0708_RS07375	COG0072	phenylalanine-tRNA ligase activity
C0708_RS07375	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0708_RS07380	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C0708_RS07385	COG4974	Belongs to the 'phage' integrase family
C0708_RS07395	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C0708_RS07400	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C0708_RS07405	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C0708_RS07410	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C0708_RS07445	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0708_RS07450	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C0708_RS07455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0708_RS07460	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C0708_RS07465	COG3313	Fe-S protein
C0708_RS07480	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0708_RS07480	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0708_RS07485	COG1609	Transcriptional regulator
C0708_RS07490	COG0814	amino acid
C0708_RS07505	COG0513	Belongs to the DEAD box helicase family
C0708_RS07520	COG2890	protein-(glutamine-N5) methyltransferase activity
C0708_RS07560	COG2824	Alkylphosphonate utilization operon protein PhnA
C0708_RS07590	COG0675	Transposase, IS605 OrfB family
C0708_RS07600	COG0588	phosphoglycerate mutase activity
C0708_RS07630	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C0708_RS07635	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C0708_RS07650	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C0708_RS07660	COG0205	6-phosphofructokinase activity
C0708_RS07690	COG1011	Hydrolase
C0708_RS07695	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0708_RS07740	COG3593	DNA synthesis involved in DNA repair
C0708_RS07765	COG3148	PFAM DTW domain containing protein
C0708_RS07770	COG1181	Belongs to the D-alanine--D-alanine ligase family
C0708_RS07785	COG0513	Belongs to the DEAD box helicase family
C0708_RS07800	COG1742	UPF0060 membrane protein
C0708_RS07830	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C0708_RS07850	COG3243	poly(R)-hydroxyalkanoic acid synthase
C0708_RS07860	COG2501	S4 domain
C0708_RS07890	COG3118	belongs to the thioredoxin family
C0708_RS07910	COG0058	SHG alpha-glucan phosphorylase activity
C0708_RS07940	COG0814	amino acid
C0708_RS07955	COG2766	serine protein kinase
C0708_RS07960	COG2718	Belongs to the UPF0229 family
C0708_RS07970	COG2186	Transcriptional regulator
C0708_RS07975	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C0708_RS07980	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C0708_RS07985	COG0586	Pfam SNARE associated Golgi protein
C0708_RS07995	COG0556	nucleotide-excision repair
C0708_RS08010	COG0569	domain protein
C0708_RS08010	COG2985	domain, Protein
C0708_RS08015	COG1196	nuclear chromosome segregation
C0708_RS08015	COG0741	lytic transglycosylase activity
C0708_RS08015	COG0739	heme binding
C0708_RS08020	COG3181	Tripartite tricarboxylate transporter family receptor
C0708_RS08035	COG4565	transcriptional regulatory protein
C0708_RS08045	COG1846	Transcriptional regulator
C0708_RS08045	COG1940	carbohydrate kinase activity
C0708_RS08050	COG0840	transmembrane signaling receptor activity
C0708_RS08055	COG3012	SEC-C Motif Domain Protein
C0708_RS08060	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C0708_RS08065	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C0708_RS08070	COG0247	lactate metabolic process
C0708_RS08080	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C0708_RS08085	COG0437	4 iron, 4 sulfur cluster binding
C0708_RS08090	COG3301	Polysulphide reductase, NrfD
C0708_RS08095	COG1138	Cytochrome C-type biogenesis protein
C0708_RS08100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0708_RS08120	COG3046	protein related to deoxyribodipyrimidine photolyase
C0708_RS08125	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0708_RS08130	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C0708_RS08130	COG0617	tRNA 3'-terminal CCA addition
C0708_RS08130	COG0517	IMP dehydrogenase activity
C0708_RS08140	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C0708_RS08145	COG0583	DNA-binding transcription factor activity
C0708_RS08155	COG4774	siderophore transport
C0708_RS08175	COG3706	GGDEF domain
C0708_RS08185	COG3706	GGDEF domain
C0708_RS08185	COG2203	Gaf domain
C0708_RS08185	COG4251	negative regulation of phosphorylation
C0708_RS08185	COG5001	Diguanylate cyclase
C0708_RS08190	COG2200	EAL domain
C0708_RS08195	COG1917	Cupin 2, conserved barrel domain protein
C0708_RS08195	COG4977	sequence-specific DNA binding
C0708_RS08200	COG0583	DNA-binding transcription factor activity
C0708_RS08205	COG2910	NAD(P)H-binding
C0708_RS08220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C0708_RS08320	COG3039	Transposase
C0708_RS08360	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C0708_RS08365	COG0830	nickel cation binding
C0708_RS08375	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
C0708_RS08385	COG0832	Belongs to the urease beta subunit family
C0708_RS08390	COG0831	urea catabolic process
C0708_RS08395	COG0829	nickel cation binding
C0708_RS08405	COG0411	ABC transporter
C0708_RS08435	COG0745	RESPONSE REGULATOR receiver
C0708_RS08515	COG3039	Transposase
C0708_RS08545	COG2801	Transposase and inactivated derivatives
C0708_RS08575	COG3550	peptidyl-serine autophosphorylation
C0708_RS08605	COG2723	6-phospho-beta-galactosidase activity
C0708_RS08635	COG1435	thymidine kinase activity
C0708_RS08640	COG1757	Na H antiporter
C0708_RS08645	COG2916	Histone family protein nucleoid-structuring protein H-NS
C0708_RS08650	COG2096	Adenosyltransferase
C0708_RS08655	COG3530	Putative quorum-sensing-regulated virulence factor
C0708_RS08660	COG0602	queuosine metabolic process
C0708_RS08665	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C0708_RS08685	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C0708_RS08695	COG0776	regulation of translation
C0708_RS08700	COG0539	negative regulation of cytoplasmic translation
C0708_RS08705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C0708_RS08710	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0708_RS08740	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C0708_RS08755	COG0583	DNA-binding transcription factor activity
C0708_RS08760	COG0745	RESPONSE REGULATOR receiver
C0708_RS08785	COG4989	oxidoreductase activity
C0708_RS08790	COG0724	RNA recognition motif
C0708_RS08800	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
C0708_RS08810	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C0708_RS08840	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0708_RS08845	COG1028	Short-chain dehydrogenase reductase Sdr
C0708_RS08850	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0708_RS08855	COG1902	pentaerythritol trinitrate reductase activity
C0708_RS08860	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
C0708_RS08870	COG4974	Belongs to the 'phage' integrase family
C0708_RS08925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C0708_RS08950	COG4245	von Willebrand factor, type A
C0708_RS08955	COG5642	Protein of unknown function (DUF2384)
C0708_RS08975	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C0708_RS08980	COG1360	Flagellar Motor Protein
C0708_RS08985	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0708_RS08990	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0708_RS09010	COG1034	ATP synthesis coupled electron transport
C0708_RS09020	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C0708_RS09025	COG0839	Belongs to the complex I subunit 6 family
C0708_RS09030	COG0713	ATP synthesis coupled electron transport
C0708_RS09045	COG1007	ATP synthesis coupled electron transport
C0708_RS09060	COG1645	bacterial-type flagellum-dependent swarming motility
C0708_RS09065	COG1160	GTP binding
C0708_RS09070	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0708_RS09075	COG2976	Protein conserved in bacteria
C0708_RS09080	COG0124	histidyl-tRNA synthetase
C0708_RS09090	COG1426	Protein conserved in bacteria
C0708_RS09100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C0708_RS09105	COG0105	UTP biosynthetic process
C0708_RS09120	COG0633	Ferredoxin
C0708_RS09125	COG0443	Heat shock 70 kDa protein
C0708_RS09130	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C0708_RS09140	COG0822	iron-sulfur transferase activity
C0708_RS09145	COG1104	cysteine desulfurase activity
C0708_RS09160	COG3154	lipid carrier protein
C0708_RS09165	COG0826	peptidase U32
C0708_RS09170	COG0826	peptidase U32
C0708_RS09180	COG2897	thiosulfate sulfurtransferase activity
C0708_RS09185	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0708_RS09190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C0708_RS09195	COG1862	Preprotein translocase
C0708_RS09200	COG0343	queuine tRNA-ribosyltransferase activity
C0708_RS09210	COG0517	IMP dehydrogenase activity
C0708_RS09215	COG0450	alkyl hydroperoxide reductase
C0708_RS09220	COG3634	alkyl hydroperoxide reductase activity
C0708_RS09245	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0708_RS09245	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C0708_RS09250	COG0509	glycine decarboxylation via glycine cleavage system
C0708_RS09255	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C0708_RS09260	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C0708_RS09285	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C0708_RS09305	COG2814	Major facilitator Superfamily
C0708_RS09315	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C0708_RS09320	COG0601	transmembrane transport
C0708_RS09330	COG0625	glutathione transferase activity
C0708_RS09345	COG0483	inositol monophosphate 1-phosphatase activity
C0708_RS09360	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0708_RS09365	COG2056	Na+-H+ antiporter family
C0708_RS09370	COG2814	Major facilitator Superfamily
C0708_RS09375	COG0583	DNA-binding transcription factor activity
C0708_RS09380	COG5001	Diguanylate cyclase
C0708_RS09395	COG2050	protein possibly involved in aromatic compounds catabolism
C0708_RS09415	COG3039	Transposase
C0708_RS09425	COG1253	flavin adenine dinucleotide binding
C0708_RS09430	COG1902	pentaerythritol trinitrate reductase activity
C0708_RS09435	COG0604	alcohol dehydrogenase
C0708_RS09445	COG0647	UMP catabolic process
C0708_RS09455	COG0367	asparagine synthase
C0708_RS09470	COG0625	glutathione transferase activity
C0708_RS09480	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C0708_RS09495	COG0564	pseudouridine synthase activity
C0708_RS09550	COG0670	Belongs to the BI1 family
C0708_RS09555	COG1289	transmembrane transporter activity
C0708_RS09560	COG2920	part of a sulfur-relay system
C0708_RS09565	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C0708_RS09575	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C0708_RS09580	COG0101	tRNA pseudouridine synthase activity
C0708_RS09590	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C0708_RS09595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0708_RS09605	COG1464	Belongs to the NlpA lipoprotein family
C0708_RS09630	COG1119	ATPase activity
C0708_RS09635	COG0574	Belongs to the PEP-utilizing enzyme family
C0708_RS09635	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C0708_RS09640	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C0708_RS09650	COG1113	amino acid transport
C0708_RS09710	COG0069	glutamate synthase activity
C0708_RS09710	COG0067	glutamate synthase
C0708_RS09710	COG0070	glutamate synthase
C0708_RS09715	COG0493	'glutamate synthase
C0708_RS09735	COG4104	PAAR repeat-containing protein
C0708_RS09745	COG0513	Belongs to the DEAD box helicase family
C0708_RS09780	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0708_RS09795	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C0708_RS09800	COG0505	Belongs to the CarA family
C0708_RS09815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C0708_RS09825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C0708_RS09830	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C0708_RS09835	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C0708_RS09845	COG4139	cobalamin transport
C0708_RS09880	COG0023	Translation Initiation Factor
C0708_RS09885	COG2119	membrane
C0708_RS09920	COG2203	Gaf domain
C0708_RS09920	COG2199	diguanylate cyclase activity
C0708_RS09940	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0708_RS09955	COG2261	transglycosylase associated protein
C0708_RS09960	COG1309	transcriptional regulator
C0708_RS09965	COG0604	alcohol dehydrogenase
C0708_RS09980	COG3039	Transposase
C0708_RS10025	COG0582	viral genome integration into host DNA
C0708_RS10050	COG0322	excinuclease ABC activity
C0708_RS10055	COG2197	response regulator
C0708_RS10060	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C0708_RS10065	COG2835	tetraacyldisaccharide 4'-kinase activity
C0708_RS10070	COG1663	tetraacyldisaccharide 4'-kinase activity
C0708_RS10075	COG1132	(ABC) transporter
C0708_RS10080	COG2333	competence protein COMEC
C0708_RS10080	COG0658	competence protein
C0708_RS10095	COG0433	COG0433 Predicted ATPase
C0708_RS10100	COG1448	Aminotransferase
C0708_RS10115	COG1199	ATP-dependent helicase activity
C0708_RS10125	COG0123	including yeast histone deacetylase and acetoin utilization protein
C0708_RS10130	COG0477	Major facilitator Superfamily
C0708_RS10140	COG1785	Belongs to the alkaline phosphatase family
C0708_RS10170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0708_RS10175	COG0765	amino acid transport
C0708_RS10190	COG0531	amino acid
C0708_RS10205	COG1253	flavin adenine dinucleotide binding
C0708_RS10210	COG0704	Plays a role in the regulation of phosphate uptake
C0708_RS10215	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0708_RS10220	COG0581	inorganic phosphate transmembrane transporter activity
C0708_RS10225	COG0573	inorganic phosphate transmembrane transporter activity
C0708_RS10230	COG0590	tRNA wobble adenosine to inosine editing
C0708_RS10240	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C0708_RS10260	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C0708_RS10265	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C0708_RS10270	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C0708_RS10275	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C0708_RS10300	COG2716	regulation of RNA biosynthetic process
C0708_RS10305	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C0708_RS10320	COG0675	Transposase, IS605 OrfB family
C0708_RS10365	COG1705	Flagellar rod assembly protein muramidase FlgJ
C0708_RS10365	COG3951	Flagellar rod assembly protein muramidase FlgJ
C0708_RS10370	COG1706	bacterial-type flagellum-dependent cell motility
C0708_RS10375	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C0708_RS10390	COG4786	Flagellar basal body rod
C0708_RS10405	COG1815	bacterial-type flagellum-dependent cell motility
C0708_RS10410	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C0708_RS10415	COG0784	Response regulator, receiver
C0708_RS10415	COG0835	chemotaxis
C0708_RS10420	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C0708_RS10435	COG0622	Phosphoesterase
C0708_RS10465	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C0708_RS10470	COG0675	Transposase, IS605 OrfB family
C0708_RS10480	COG0697	spore germination
C0708_RS10520	COG1278	Cold shock
C0708_RS10530	COG0675	Transposase, IS605 OrfB family
C0708_RS10545	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
C0708_RS10570	COG3132	Protein of unknown function, DUF480
C0708_RS10580	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0708_RS10600	COG0489	protein tyrosine kinase activity
C0708_RS10600	COG3206	protein involved in exopolysaccharide biosynthesis
C0708_RS10605	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C0708_RS10655	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C0708_RS10680	COG0438	transferase activity, transferring glycosyl groups
C0708_RS10720	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
C0708_RS10745	COG1737	Transcriptional regulator
C0708_RS10750	COG0469	pyruvate kinase activity
C0708_RS10765	COG1960	acyl-CoA dehydrogenase activity
C0708_RS10795	COG1484	DNA-dependent DNA replication
C0708_RS10800	COG4584	PFAM Integrase catalytic
C0708_RS10815	COG0583	DNA-binding transcription factor activity
C0708_RS10830	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C0708_RS10845	COG2003	Belongs to the UPF0758 family
C0708_RS10910	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0708_RS10920	COG1309	transcriptional regulator
C0708_RS10935	COG1946	Acyl-CoA thioesterase
C0708_RS10960	COG0009	L-threonylcarbamoyladenylate synthase
C0708_RS10970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C0708_RS10975	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C0708_RS10975	COG0512	Glutamine amidotransferase of anthranilate synthase
C0708_RS10980	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C0708_RS10990	COG0133	tryptophan synthase activity
C0708_RS11000	COG1396	sequence-specific DNA binding
C0708_RS11005	COG3550	peptidyl-serine autophosphorylation
C0708_RS11040	COG5507	3-demethylubiquinone-9 3-methyltransferase
C0708_RS11045	COG2814	Major facilitator Superfamily
C0708_RS11055	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C0708_RS11060	COG1845	cytochrome c oxidase, subunit III
C0708_RS11065	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C0708_RS11070	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0708_RS11075	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C0708_RS11080	COG0583	DNA-binding transcription factor activity
C0708_RS11100	COG1846	Transcriptional regulator
C0708_RS11130	COG0745	RESPONSE REGULATOR receiver
C0708_RS11140	COG0708	Exodeoxyribonuclease III
C0708_RS11150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0708_RS11155	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0708_RS11170	COG0095	Lipoate-protein ligase
C0708_RS11190	COG2391	methyltransferase activity
C0708_RS11200	COG0640	Transcriptional regulator
C0708_RS11210	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0708_RS11220	COG1285	pathogenesis
C0708_RS11250	COG0484	heat shock protein binding
C0708_RS11255	COG0443	Heat shock 70 kDa protein
C0708_RS11260	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C0708_RS11265	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C0708_RS11275	COG0497	DNA recombination
C0708_RS11285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0708_RS11290	COG1136	(ABC) transporter
C0708_RS11290	COG0577	efflux transmembrane transporter activity
C0708_RS11295	COG1538	Outer membrane efflux protein
C0708_RS11300	COG2375	cellular response to nickel ion
C0708_RS11315	COG2916	Histone family protein nucleoid-structuring protein H-NS
C0708_RS11320	COG0583	DNA-binding transcription factor activity
C0708_RS11325	COG3048	D-serine ammonia-lyase activity
C0708_RS11335	COG0538	isocitrate dehydrogenase activity
C0708_RS11365	COG0456	acetyltransferase
C0708_RS11370	COG1187	pseudouridine synthase activity
C0708_RS11380	COG0482	sulfurtransferase activity
C0708_RS11385	COG2915	High frequency lysogenization protein hflD homolog
C0708_RS11390	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C0708_RS11395	COG2850	peptidyl-arginine hydroxylation
C0708_RS11405	COG3264	Mechanosensitive ion channel
C0708_RS11405	COG1196	nuclear chromosome segregation
C0708_RS11415	COG2706	6-phosphogluconolactonase activity
C0708_RS11440	COG0746	molybdenum cofactor guanylyltransferase activity
C0708_RS11445	COG1763	Mo-molybdopterin cofactor biosynthetic process
C0708_RS11450	COG1289	transmembrane transporter activity
C0708_RS11455	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C0708_RS11485	COG3220	belongs to the UPF0276 family
C0708_RS11495	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
C0708_RS11505	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C0708_RS11540	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0708_RS11545	COG0083	homoserine kinase activity
C0708_RS11560	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C0708_RS11580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C0708_RS11590	COG0745	RESPONSE REGULATOR receiver
C0708_RS11605	COG4988	ABC transporter
C0708_RS11610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C0708_RS11630	COG1720	tRNA m6t6A37 methyltransferase activity
C0708_RS11645	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C0708_RS11650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C0708_RS11655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0708_RS11665	COG2190	(PTS) system
C0708_RS11680	COG0420	3'-5' exonuclease activity
C0708_RS11690	COG2974	May be involved in recombination
C0708_RS11705	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C0708_RS11705	COG4651	solute:proton antiporter activity
C0708_RS11745	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C0708_RS11750	COG1917	Cupin 2, conserved barrel domain protein
C0708_RS11750	COG1396	sequence-specific DNA binding
C0708_RS11755	COG1012	belongs to the aldehyde dehydrogenase family
C0708_RS11765	COG0531	amino acid
C0708_RS11770	COG0531	amino acid
C0708_RS11790	COG3384	dioxygenase
C0708_RS11820	COG2205	protein histidine kinase activity
C0708_RS11820	COG0784	Response regulator, receiver
C0708_RS11845	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C0708_RS11850	COG0791	NLP P60 protein
C0708_RS11860	COG3118	belongs to the thioredoxin family
C0708_RS11870	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C0708_RS11875	COG0788	formyltetrahydrofolate deformylase activity
C0708_RS11900	COG0739	heme binding
C0708_RS11900	COG0741	lytic transglycosylase activity
C0708_RS11900	COG1196	nuclear chromosome segregation
C0708_RS11915	COG0673	inositol 2-dehydrogenase activity
C0708_RS11945	COG1032	radical SAM domain protein
C0708_RS12000	COG0281	malic enzyme
C0708_RS12005	COG2207	Transcriptional regulator
C0708_RS12025	COG2233	PERMEase
C0708_RS12030	COG0095	Lipoate-protein ligase
C0708_RS12035	COG1115	amino acid carrier protein
C0708_RS12040	COG0019	diaminopimelate decarboxylase activity
C0708_RS12050	COG0678	peroxiredoxin activity
C0708_RS12055	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C0708_RS12065	COG1126	abc transporter atp-binding protein
C0708_RS12070	COG0765	amino acid transport
C0708_RS12075	COG4597	amino acid ABC transporter
C0708_RS12080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0708_RS12100	COG0545	Peptidyl-prolyl cis-trans isomerase
C0708_RS12105	COG3142	Participates in the control of copper homeostasis
C0708_RS12120	COG4783	chaperone-mediated protein folding
C0708_RS12130	COG5002	protein histidine kinase activity
C0708_RS12135	COG0745	RESPONSE REGULATOR receiver
C0708_RS12150	COG3284	Transcriptional regulator
C0708_RS12165	COG0697	spore germination
C0708_RS12170	COG0667	Aldo Keto reductase
C0708_RS12180	COG3385	transposase activity
C0708_RS12200	COG1566	PFAM secretion protein HlyD family protein
C0708_RS12225	COG0602	queuosine metabolic process
C0708_RS12230	COG1328	CTP reductase activity
C0708_RS12240	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C0708_RS12245	COG3115	cell septum assembly
C0708_RS12270	COG3108	Peptidase M15
C0708_RS12275	COG3385	transposase activity
C0708_RS12280	COG2989	Protein conserved in bacteria
C0708_RS12295	COG0463	Glycosyl transferase, family 2
C0708_RS12310	COG0366	Alpha amylase catalytic
C0708_RS12355	COG3706	GGDEF domain
C0708_RS12360	COG0037	tRNA processing
C0708_RS12385	COG0531	amino acid
C0708_RS12390	COG0814	amino acid
C0708_RS12405	COG0825	malonyl-CoA metabolic process
C0708_RS12415	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C0708_RS12425	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0708_RS12430	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C0708_RS12435	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C0708_RS12450	COG0750	zinc metalloprotease
C0708_RS12460	COG0575	Belongs to the CDS family
C0708_RS12465	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C0708_RS12470	COG0233	cytoplasmic translational termination
C0708_RS12475	COG0528	UMP kinase activity
C0708_RS12480	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C0708_RS12485	COG0052	Belongs to the universal ribosomal protein uS2 family
C0708_RS12490	COG0024	Methionine aminopeptidase
C0708_RS12495	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C0708_RS12500	COG2171	N-acyltransferase activity
C0708_RS12510	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0708_RS12510	COG1263	PTS System
C0708_RS12520	COG4580	involved in the transport of maltose and maltodextrins
C0708_RS12535	COG3098	single-species biofilm formation
C0708_RS12560	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C0708_RS12590	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0708_RS12595	COG0473	3-isopropylmalate dehydrogenase activity
C0708_RS12605	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C0708_RS12620	COG0583	DNA-binding transcription factor activity
C0708_RS12625	COG0840	transmembrane signaling receptor activity
C0708_RS12630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C0708_RS12645	COG1477	protein flavinylation
C0708_RS12650	COG2871	sodium ion transport
C0708_RS12655	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C0708_RS12660	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C0708_RS12665	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C0708_RS12670	COG1805	sodium ion transport
C0708_RS12675	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C0708_RS12680	COG0271	Belongs to the BolA IbaG family
C0708_RS12685	COG2813	Specifically methylates the guanine in position
C0708_RS12695	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C0708_RS12705	COG2211	Major facilitator Superfamily
C0708_RS12715	COG1666	GTP binding
C0708_RS12720	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C0708_RS12730	COG0659	secondary active sulfate transmembrane transporter activity
C0708_RS12735	COG5002	protein histidine kinase activity
C0708_RS12735	COG5000	phosphorelay sensor kinase activity
C0708_RS12745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0708_RS12750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0708_RS12765	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C0708_RS12775	COG1151	hydroxylamine reductase activity
C0708_RS12780	COG0783	Belongs to the Dps family
C0708_RS12820	COG4221	oxidoreductase activity
C0708_RS12830	COG0415	Belongs to the DNA photolyase family
C0708_RS12835	COG0789	Transcriptional regulator
C0708_RS12840	COG3272	Protein of unknown function (DUF1722)
C0708_RS12865	COG0077	Prephenate dehydratase
C0708_RS12865	COG1605	Chorismate mutase
C0708_RS12895	COG2133	pyrroloquinoline quinone binding
C0708_RS12910	COG2084	Dehydrogenase
C0708_RS12925	COG3622	Belongs to the hyi family
C0708_RS12935	COG2610	gluconate transmembrane transporter activity
C0708_RS12955	COG0300	oxidoreductase activity
C0708_RS13000	COG3813	Protein conserved in bacteria
C0708_RS13015	COG1280	lysine exporter protein (LysE YggA)
C0708_RS13025	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C0708_RS13065	COG3279	Response regulator of the LytR AlgR family
C0708_RS13070	COG1966	Carbon starvation protein
C0708_RS13080	COG0114	fumarate hydratase activity
C0708_RS13095	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C0708_RS13110	COG0737	Belongs to the 5'-nucleotidase family
C0708_RS13130	COG2204	response regulator
C0708_RS13135	COG0545	Peptidyl-prolyl cis-trans isomerase
C0708_RS13145	COG2900	Belongs to the SlyX family
C0708_RS13150	COG1047	Peptidyl-prolyl cis-trans
C0708_RS13155	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C0708_RS13165	COG0784	Response regulator, receiver
C0708_RS13165	COG0835	chemotaxis
C0708_RS13170	COG0429	hydrolase of the alpha beta-hydrolase fold
C0708_RS13175	COG3706	GGDEF domain
C0708_RS13175	COG4251	negative regulation of phosphorylation
C0708_RS13175	COG5001	Diguanylate cyclase
C0708_RS13175	COG2203	Gaf domain
C0708_RS13180	COG3089	Belongs to the UPF0270 family
C0708_RS13185	COG3954	Phosphoribulokinase
C0708_RS13200	COG1765	OsmC-like protein
C0708_RS13210	COG2226	methyltransferase
C0708_RS13255	COG3721	Heme iron utilization protein
C0708_RS13305	COG0741	lytic transglycosylase activity
C0708_RS13310	COG0488	(ABC) transporter
C0708_RS13320	COG2252	PERMEase
C0708_RS13325	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C0708_RS13330	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C0708_RS13335	COG3178	'Phosphotransferase
C0708_RS13350	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C0708_RS13355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C0708_RS13360	COG2967	ApaG domain
C0708_RS13365	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C0708_RS13385	COG3314	Sporulation integral membrane protein YlbJ
C0708_RS13390	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C0708_RS13395	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C0708_RS13400	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C0708_RS13405	COG0142	geranyltranstransferase activity
C0708_RS13410	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C0708_RS13415	COG0330	HflC and HflK could
C0708_RS13425	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C0708_RS13430	COG1923	regulation of RNA biosynthetic process
C0708_RS13440	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C0708_RS13450	COG0802	atpase or kinase
C0708_RS13455	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C0708_RS13455	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C0708_RS13475	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C0708_RS13480	COG2011	ABC-type metal ion transport system permease component
C0708_RS13485	COG1464	Belongs to the NlpA lipoprotein family
C0708_RS13520	COG0784	Response regulator, receiver
C0708_RS13520	COG2198	Histidine kinase
C0708_RS13520	COG5002	protein histidine kinase activity
C0708_RS13540	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C0708_RS13555	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C0708_RS13560	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C0708_RS13565	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0708_RS13570	COG2716	regulation of RNA biosynthetic process
C0708_RS13575	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C0708_RS13580	COG3013	Belongs to the UPF0304 family
C0708_RS13590	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C0708_RS13595	COG0857	belongs to the CobB CobQ family
C0708_RS13595	COG0280	phosphate acetyltransferase
C0708_RS13600	COG0440	acetolactate synthase activity
C0708_RS13605	COG0028	Belongs to the TPP enzyme family
C0708_RS13630	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C0708_RS13635	COG0473	3-isopropylmalate dehydrogenase activity
C0708_RS13640	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C0708_RS13645	COG0066	3-isopropylmalate dehydratase activity
C0708_RS13660	COG4143	(ABC) transporter
C0708_RS13670	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C0708_RS13675	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C0708_RS13730	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C0708_RS13745	COG0671	phosphoesterase, PA-phosphatase related
C0708_RS13755	COG0583	DNA-binding transcription factor activity
C0708_RS13760	COG2076	Multidrug Resistance protein
C0708_RS13770	COG0346	lactoylglutathione lyase activity
C0708_RS13775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C0708_RS13780	COG1643	Atp-dependent helicase
C0708_RS13790	COG1489	DNA binding
C0708_RS13795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C0708_RS13800	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C0708_RS13810	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C0708_RS13815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C0708_RS13830	COG0842	Transport permease protein
C0708_RS13835	COG1131	(ABC) transporter
C0708_RS13850	COG0163	prenyltransferase activity
C0708_RS13855	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0708_RS13860	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C0708_RS13875	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C0708_RS13890	COG1136	(ABC) transporter
C0708_RS13930	COG0529	Catalyzes the synthesis of activated sulfate
C0708_RS13935	COG3273	potassium ion transport
C0708_RS13935	COG0471	metal ion transport
C0708_RS13940	COG2895	sulfate adenylyltransferase (ATP) activity
C0708_RS13945	COG0175	sulfate reduction
C0708_RS13950	COG1648	precorrin-2 dehydrogenase activity
C0708_RS13950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0708_RS13955	COG0330	HflC and HflK could
C0708_RS13960	COG1585	Membrane protein implicated in regulation of membrane protease activity
C0708_RS13970	COG0673	inositol 2-dehydrogenase activity
C0708_RS13980	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C0708_RS13985	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0708_RS13995	COG3036	rescue of stalled ribosome
C0708_RS14010	COG0138	bifunctional purine biosynthesis protein purh
C0708_RS14015	COG0151	Belongs to the GarS family
C0708_RS14050	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C0708_RS14055	COG0358	DNA primase activity
C0708_RS14060	COG1610	YqeY-like protein
C0708_RS14065	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C0708_RS14070	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C0708_RS14085	COG1238	metal cluster binding
C0708_RS14090	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C0708_RS14100	COG0585	pseudouridine synthase activity
C0708_RS14110	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C0708_RS14115	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C0708_RS14120	COG0148	phosphopyruvate hydratase activity
C0708_RS14125	COG0504	CTP synthase activity
C0708_RS14130	COG3956	TIGRFAM MazG family protein
C0708_RS14135	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0708_RS14140	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0708_RS14150	COG4807	Protein conserved in bacteria
C0708_RS14155	COG3023	N-Acetylmuramoyl-L-alanine amidase
C0708_RS14160	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C0708_RS14165	COG1381	Involved in DNA repair and RecF pathway recombination
C0708_RS14175	COG0571	ribonuclease III activity
C0708_RS14180	COG0681	Belongs to the peptidase S26 family
C0708_RS14185	COG0481	GTPase activity
C0708_RS14200	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C0708_RS14205	COG1595	DNA-templated transcription, initiation
C0708_RS14210	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C0708_RS14220	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C0708_RS14235	COG0583	DNA-binding transcription factor activity
C0708_RS14275	COG0126	phosphoglycerate kinase activity
C0708_RS14280	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0708_RS14285	COG1940	carbohydrate kinase activity
C0708_RS14290	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C0708_RS14295	COG2816	NAD+ diphosphatase activity
C0708_RS14305	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C0708_RS14320	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C0708_RS14325	COG1028	Short-chain dehydrogenase reductase Sdr
C0708_RS14335	COG1505	serine-type exopeptidase activity
C0708_RS14340	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C0708_RS14345	COG0765	amino acid transport
C0708_RS14350	COG0765	amino acid transport
C0708_RS14355	COG1126	abc transporter atp-binding protein
C0708_RS14360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0708_RS14365	COG3174	membrane
C0708_RS14370	COG0110	maltose O-acetyltransferase activity
C0708_RS14400	COG1942	4-Oxalocrotonate Tautomerase
C0708_RS14410	COG0583	DNA-binding transcription factor activity
C0708_RS14415	COG0165	Argininosuccinate lyase
C0708_RS14425	COG0137	argininosuccinate synthase activity
C0708_RS14435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C0708_RS14440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C0708_RS14450	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C0708_RS14455	COG3447	MASE1 domain protein
C0708_RS14455	COG5001	Diguanylate cyclase
C0708_RS14455	COG5002	protein histidine kinase activity
C0708_RS14460	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C0708_RS14495	COG0583	DNA-binding transcription factor activity
C0708_RS14500	COG1380	Effector of murein hydrolase LrgA
C0708_RS14505	COG1346	cytolysis
C0708_RS14510	COG0527	aspartate kinase activity
C0708_RS14510	COG0460	homoserine dehydrogenase
C0708_RS14540	COG1218	3'(2'),5'-bisphosphate nucleotidase
C0708_RS14545	COG0494	nUDIX hydrolase
C0708_RS14550	COG1011	Hydrolase
C0708_RS14565	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C0708_RS14580	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C0708_RS14590	COG3156	type II secretion system protein K
C0708_RS14595	COG4795	General secretion pathway protein
C0708_RS14600	COG2165	general secretion pathway protein
C0708_RS14610	COG2165	general secretion pathway protein
C0708_RS14615	COG1459	type II secretion system
C0708_RS14620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0708_RS14630	COG3031	protein transport across the cell outer membrane
C0708_RS14640	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C0708_RS14645	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C0708_RS14665	COG3133	Outer membrane lipoprotein
C0708_RS14670	COG3025	triphosphatase activity
C0708_RS14675	COG1392	Phosphate transport regulator
C0708_RS14680	COG0306	phosphate transporter
C0708_RS14685	COG0617	tRNA 3'-terminal CCA addition
C0708_RS14690	COG3409	Peptidoglycan-binding domain 1 protein
C0708_RS14690	COG3267	Type II secretory pathway component ExeA
C0708_RS14700	COG1194	a g-specific adenine glycosylase
C0708_RS14705	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C0708_RS14720	COG3240	lipase activity
C0708_RS14730	COG3009	Protein conserved in bacteria
C0708_RS14735	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0708_RS14735	COG3008	intermembrane lipid transfer
C0708_RS14740	COG2995	paraquat-inducible protein a
C0708_RS14750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C0708_RS14760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C0708_RS14770	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C0708_RS14775	COG0297	glycogen (starch) synthase activity
C0708_RS14815	COG1757	Na H antiporter
C0708_RS14820	COG0583	DNA-binding transcription factor activity
C0708_RS14825	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C0708_RS14835	COG1176	ABC-type spermidine putrescine transport system, permease component I
C0708_RS14840	COG1177	transmembrane transport
C0708_RS14845	COG1012	belongs to the aldehyde dehydrogenase family
C0708_RS14850	COG0109	protoheme IX farnesyltransferase activity
C0708_RS14875	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C0708_RS14885	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C0708_RS14885	COG1565	acr, cog1565
C0708_RS14890	COG1444	tRNA N-acetyltransferase activity
C0708_RS14910	COG1803	Methylglyoxal synthase
C0708_RS14925	COG0252	asparaginase activity
C0708_RS14945	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C0708_RS14945	COG1263	PTS System
C0708_RS14950	COG0366	Alpha amylase catalytic
C0708_RS14955	COG0110	maltose O-acetyltransferase activity
C0708_RS14960	COG1522	sequence-specific DNA binding
C0708_RS14990	COG3068	Protein conserved in bacteria
C0708_RS15000	COG0739	heme binding
C0708_RS15020	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C0708_RS15025	COG1121	(ABC) transporter
C0708_RS15030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C0708_RS15045	COG1573	uracil-dna glycosylase
C0708_RS15055	COG2827	Endonuclease containing a URI domain
C0708_RS15070	COG1842	Phage shock protein A
C0708_RS15100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C0708_RS15175	COG1289	transmembrane transporter activity
C0708_RS15180	COG1566	PFAM secretion protein HlyD family protein
C0708_RS15200	COG3150	esterase
C0708_RS15210	COG3151	Protein conserved in bacteria
C0708_RS15215	COG0494	nUDIX hydrolase
C0708_RS15220	COG1538	Outer membrane efflux protein
C0708_RS15230	COG1560	Kdo2-lipid A biosynthetic process
C0708_RS15245	COG2771	luxR family
C0708_RS15260	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C0708_RS15265	COG2213	PTS system mannitol-specific
C0708_RS15265	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0708_RS15270	COG0246	Mannitol dehydrogenase
C0708_RS15275	COG3722	fumarate hydratase activity
C0708_RS15315	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0708_RS15320	COG0513	Belongs to the DEAD box helicase family
C0708_RS15350	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C0708_RS15355	COG0596	Alpha beta hydrolase
C0708_RS15360	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C0708_RS15375	COG3291	Pkd domain containing protein
C0708_RS15380	COG2949	membrane
C0708_RS15385	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C0708_RS15395	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C0708_RS15425	COG2873	o-acetylhomoserine
C0708_RS15450	COG4221	oxidoreductase activity
C0708_RS15470	COG1285	pathogenesis
C0708_RS15485	COG1368	sulfuric ester hydrolase activity
C0708_RS15490	COG1522	sequence-specific DNA binding
C0708_RS15500	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C0708_RS15510	COG1058	Belongs to the CinA family
C0708_RS15510	COG1546	Belongs to the CinA family
C0708_RS15515	COG1988	membrane-bound metal-dependent
C0708_RS15530	COG0561	phosphatase activity
C0708_RS15535	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C0708_RS15545	COG1011	Hydrolase
C0708_RS15560	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C0708_RS15565	COG0019	diaminopimelate decarboxylase activity
C0708_RS15575	COG1965	Belongs to the frataxin family
C0708_RS15580	COG0400	carboxylic ester hydrolase activity
C0708_RS15585	COG3072	Adenylate cyclase
C0708_RS15590	COG0181	hydroxymethylbilane synthase activity
C0708_RS15600	COG2959	enzyme of heme biosynthesis
C0708_RS15605	COG3071	HemY protein
C0708_RS15610	COG0312	modulator of DNA gyrase
C0708_RS15615	COG3028	Belongs to the UPF0307 family
C0708_RS15625	COG2926	Belongs to the UPF0265 family
C0708_RS15660	COG1396	sequence-specific DNA binding
C0708_RS15665	COG3135	benzoate transporter
C0708_RS15695	COG3047	cAMP biosynthetic process
C0708_RS15730	COG1278	Cold shock
C0708_RS15735	COG3385	transposase activity
C0708_RS15765	COG3706	GGDEF domain
C0708_RS15770	COG0347	Belongs to the P(II) protein family
C0708_RS15775	COG0004	ammonium transporteR
C0708_RS15800	COG2259	Doxx family
C0708_RS15815	COG0583	DNA-binding transcription factor activity
C0708_RS15850	COG3842	ATPase activity
C0708_RS15880	COG0456	acetyltransferase
C0708_RS15885	COG0753	catalase activity
C0708_RS15905	COG0494	nUDIX hydrolase
C0708_RS15920	COG2957	Belongs to the agmatine deiminase family
C0708_RS15935	COG2957	Belongs to the agmatine deiminase family
C0708_RS15940	COG0583	DNA-binding transcription factor activity
C0708_RS15955	COG1461	Dihydroxyacetone kinase
C0708_RS15960	COG2376	Dihydroxyacetone kinase
C0708_RS15965	COG2252	PERMEase
C0708_RS15970	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C0708_RS16010	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C0708_RS16015	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C0708_RS16020	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C0708_RS16025	COG0049	tRNA binding
C0708_RS16030	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C0708_RS16035	COG2168	tRNA wobble position uridine thiolation
C0708_RS16045	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C0708_RS16050	COG0251	oxidation-reduction process
C0708_RS16055	COG2964	Protein conserved in bacteria
C0708_RS16060	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C0708_RS16065	COG0085	RNA polymerase activity
C0708_RS16070	COG0222	ribosome binding
C0708_RS16075	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C0708_RS16080	COG0081	regulation of translation
C0708_RS16085	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C0708_RS16090	COG0250	Participates in transcription elongation, termination and antitermination
C0708_RS16105	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C0708_RS16130	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C0708_RS16135	COG0569	domain protein
C0708_RS16140	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0708_RS16150	COG3005	denitrification pathway
C0708_RS16155	COG0243	molybdopterin cofactor binding
C0708_RS16205	COG2204	response regulator
C0708_RS16235	COG0517	IMP dehydrogenase activity
C0708_RS16235	COG0516	GMP reductase activity
C0708_RS16245	COG1522	sequence-specific DNA binding
C0708_RS16250	COG2502	aspartate--ammonia ligase
C0708_RS16255	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C0708_RS16260	COG0542	response to heat
C0708_RS16270	COG0564	pseudouridine synthase activity
C0708_RS16275	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C0708_RS16280	COG3681	Belongs to the UPF0597 family
C0708_RS16285	COG2964	Protein conserved in bacteria
C0708_RS16290	COG3385	transposase activity
C0708_RS16295	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C0708_RS16300	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C0708_RS16305	COG1979	alcohol dehydrogenase
C0708_RS16315	COG3040	lipid binding
C0708_RS16360	COG1438	arginine binding
C0708_RS16365	COG1288	antiporter activity
C0708_RS16370	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C0708_RS16415	COG1609	Transcriptional regulator
C0708_RS16430	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C0708_RS16435	COG2017	converts alpha-aldose to the beta-anomer
C0708_RS16445	COG1968	undecaprenyl-diphosphatase activity
C0708_RS16450	COG3806	Anti-sigma factor
C0708_RS16455	COG1595	DNA-templated transcription, initiation
C0708_RS16475	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C0708_RS16480	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C0708_RS16500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0708_RS16505	COG1131	(ABC) transporter
C0708_RS16510	COG0842	Transport permease protein
C0708_RS16515	COG0842	Transport permease protein
C0708_RS16520	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C0708_RS16530	COG2116	formate transmembrane transporter activity
C0708_RS16535	COG1648	precorrin-2 dehydrogenase activity
C0708_RS16535	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C0708_RS16545	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C0708_RS16550	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C0708_RS16560	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C0708_RS16575	COG2050	protein possibly involved in aromatic compounds catabolism
C0708_RS16590	COG2258	MOSC domain
C0708_RS16595	COG1177	transmembrane transport
C0708_RS16600	COG1176	ABC-type spermidine putrescine transport system, permease component I
C0708_RS16605	COG3842	ATPase activity
C0708_RS16625	COG0174	glutamine synthetase
C0708_RS16645	COG3045	CreA protein
C0708_RS16650	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C0708_RS16655	COG0443	Heat shock 70 kDa protein
C0708_RS16670	COG0366	Alpha amylase catalytic
C0708_RS16680	COG4310	Domain of unknown function (DUF2172)
C0708_RS16715	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0708_RS16730	COG2205	protein histidine kinase activity
C0708_RS16745	COG0702	epimerase
C0708_RS16750	COG0254	rRNA binding
C0708_RS16760	COG1309	transcriptional regulator
C0708_RS16770	COG3385	transposase activity
C0708_RS16785	COG0129	dihydroxy-acid dehydratase activity
C0708_RS16795	COG3978	acetolactate synthase activity
C0708_RS16810	COG0606	chelatase, subunit chli
C0708_RS16820	COG0204	Acyl-transferase
C0708_RS16825	COG1683	Conserved Protein
C0708_RS16840	COG1335	isochorismatase
C0708_RS16850	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C0708_RS16855	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C0708_RS16860	COG3639	organic phosphonate transmembrane transporter activity
C0708_RS16865	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C0708_RS16870	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C0708_RS16880	COG3084	Protein conserved in bacteria
C0708_RS16885	COG5001	Diguanylate cyclase
C0708_RS16885	COG2203	Gaf domain
C0708_RS16885	COG4251	negative regulation of phosphorylation
C0708_RS16885	COG3706	GGDEF domain
C0708_RS16900	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C0708_RS16905	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C0708_RS16910	COG1561	YicC-like family, N-terminal region
C0708_RS16985	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0708_RS17005	COG1857	crispr-associated protein
C0708_RS17045	COG0859	PFAM glycosyl transferase family 9
C0708_RS17055	COG0859	PFAM glycosyl transferase family 9
C0708_RS17060	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C0708_RS17065	COG2990	Protein conserved in bacteria
C0708_RS17080	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C0708_RS17085	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C0708_RS17090	COG2003	Belongs to the UPF0758 family
C0708_RS17095	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C0708_RS17100	COG0756	dUTP diphosphatase activity
C0708_RS17105	COG1309	transcriptional regulator
C0708_RS17120	COG0668	transmembrane transport
C0708_RS17130	COG0166	Belongs to the GPI family
C0708_RS17135	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C0708_RS17140	COG0583	DNA-binding transcription factor activity
C0708_RS17150	COG1042	CoA-binding domain protein
C0708_RS17150	COG0045	succinate-CoA ligase (ADP-forming) activity
C0708_RS17150	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C0708_RS17175	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C0708_RS17180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C0708_RS17190	COG0006	proline dipeptidase activity
C0708_RS17195	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C0708_RS17200	COG1250	3-hydroxyacyl-CoA dehydrogenase
C0708_RS17200	COG1024	Enoyl-CoA hydratase
C0708_RS17205	COG0183	Belongs to the thiolase family
C0708_RS17245	COG0425	Belongs to the sulfur carrier protein TusA family
C0708_RS17250	COG0251	oxidation-reduction process
C0708_RS17265	COG2885	chlorophyll binding
C0708_RS17275	COG1335	isochorismatase
C0708_RS17280	COG2818	Glycosylase
C0708_RS17285	COG0752	glycyl-tRNA synthetase alpha subunit
C0708_RS17290	COG0751	glycine-tRNA ligase activity
C0708_RS17325	COG3033	Beta-eliminating lyase
C0708_RS17335	COG0348	domain, Protein
C0708_RS17345	COG0446	pyridine nucleotide-disulphide oxidoreductase
C0708_RS17350	COG1773	rubredoxin
C0708_RS17350	COG0426	domain, Protein
C0708_RS17355	COG3604	Transcriptional regulator
C0708_RS17360	COG1609	Transcriptional regulator
C0708_RS17400	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0708_RS17415	COG2960	long-chain fatty acid transporting porin activity
C0708_RS17440	COG3118	belongs to the thioredoxin family
C0708_RS17450	COG0248	Ppx GppA phosphatase
C0708_RS17465	COG0742	ribosomal rna small subunit methyltransferase
C0708_RS17490	COG0805	protein transport
C0708_RS17495	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0708_RS17500	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0708_RS17505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C0708_RS17510	COG3165	ubiquinone biosynthetic process from chorismate
C0708_RS17520	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C0708_RS17525	COG0402	S-adenosylhomocysteine deaminase activity
C0708_RS17560	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C0708_RS17565	COG0848	biopolymer transport protein
C0708_RS17570	COG0811	peptide transport
C0708_RS17575	COG0811	peptide transport
C0708_RS17585	COG2771	luxR family
C0708_RS17590	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0708_RS17595	COG0501	Belongs to the peptidase M48B family
C0708_RS17615	COG0542	response to heat
C0708_RS17620	COG0071	Belongs to the small heat shock protein (HSP20) family
C0708_RS17725	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C0708_RS17730	COG1349	DNA-binding transcription factor activity
C0708_RS17735	COG0745	RESPONSE REGULATOR receiver
C0708_RS17740	COG2205	protein histidine kinase activity
C0708_RS17750	COG4452	Inner membrane protein CreD
C0708_RS17755	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C0708_RS17760	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C0708_RS17765	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C0708_RS17770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C0708_RS17775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C0708_RS17780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C0708_RS17785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C0708_RS17795	COG0356	it plays a direct role in the translocation of protons across the membrane
C0708_RS17805	COG1475	DNA binding
C0708_RS17810	COG1192	Involved in chromosome partitioning
C0708_RS17815	COG0357	Ribosomal RNA small subunit methyltransferase G
C0708_RS17820	COG0445	tRNA wobble uridine modification
C0708_RS17825	COG0716	FMN binding
C0708_RS17830	COG4774	siderophore transport
C0708_RS17840	COG1120	ATPase activity
C0708_RS17855	COG3385	transposase activity
C0708_RS17860	COG3550	peptidyl-serine autophosphorylation
C0708_RS17910	COG4974	Belongs to the 'phage' integrase family
C0708_RS17915	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C0708_RS17920	COG0706	membrane insertase activity
C0708_RS17925	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C0708_RS17930	COG0594	ribonuclease P activity
C0708_RS17935	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C0708_RS17940	COG1126	abc transporter atp-binding protein
C0708_RS17955	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C0708_RS17960	COG0592	DNA-directed DNA polymerase activity
C0708_RS17970	COG0187	DNA topoisomerase II activity
C0708_RS17975	COG2801	Transposase and inactivated derivatives
C0708_RS17980	COG2207	Transcriptional regulator
C0708_RS17985	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C0708_RS17995	COG0071	Belongs to the small heat shock protein (HSP20) family
C0708_RS18000	COG3977	Valine--pyruvate aminotransferase
C0708_RS18020	COG0745	RESPONSE REGULATOR receiver
C0708_RS18050	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0708_RS18055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0708_RS18055	COG4191	Histidine kinase
C0708_RS18060	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C0708_RS18065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0708_RS18070	COG1309	transcriptional regulator
C0708_RS18100	COG0561	phosphatase activity
C0708_RS18110	COG0110	maltose O-acetyltransferase activity
C0708_RS18115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0708_RS18120	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C0708_RS18125	COG1758	RNA polymerase activity
C0708_RS18185	COG0589	response to stress
C0708_RS18190	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C0708_RS18195	COG3706	GGDEF domain
C0708_RS18200	COG1528	Iron-storage protein
C0708_RS18210	COG2223	nitrite transmembrane transporter activity
C0708_RS18215	COG1280	lysine exporter protein (LysE YggA)
C0708_RS18230	COG3039	Transposase
C0708_RS18250	COG3275	phosphorelay sensor kinase activity
C0708_RS18255	COG3279	Response regulator of the LytR AlgR family
C0708_RS18260	COG2223	nitrite transmembrane transporter activity
C0708_RS18265	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C0708_RS18270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C0708_RS18325	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C0708_RS18330	COG2166	iron-sulfur cluster assembly
C0708_RS18335	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C0708_RS18355	COG1063	alcohol dehydrogenase
C0708_RS18360	COG0156	8-amino-7-oxononanoate synthase activity
C0708_RS18370	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C0708_RS18445	COG1580	Controls the rotational direction of flagella during chemotaxis
C0708_RS18450	COG3161	chorismate lyase activity
C0708_RS18455	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C0708_RS18460	COG2937	Belongs to the GPAT DAPAT family
C0708_RS18465	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C0708_RS18480	COG0534	Mate efflux family protein
C0708_RS18485	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C0708_RS18490	COG2205	protein histidine kinase activity
C0708_RS18495	COG0745	RESPONSE REGULATOR receiver
C0708_RS18505	COG1045	serine acetyltransferase
C0708_RS18515	COG3074	FtsZ-dependent cytokinesis
C0708_RS18520	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C0708_RS18525	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0708_RS18525	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C0708_RS18530	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C0708_RS18565	COG1609	Transcriptional regulator
C0708_RS18570	COG3250	beta-galactosidase activity
C0708_RS18575	COG2731	YhcH YjgK YiaL family protein
C0708_RS18585	COG2801	Transposase and inactivated derivatives
C0708_RS18595	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C0708_RS18605	COG0385	Bile acid
C0708_RS18635	COG0583	DNA-binding transcription factor activity
C0708_RS18640	COG1079	Belongs to the binding-protein-dependent transport system permease family
C0708_RS18645	COG4603	Belongs to the binding-protein-dependent transport system permease family
C0708_RS18650	COG3845	ABC transporter
C0708_RS18655	COG1744	ABC transporter substrate-binding protein PnrA-like
C0708_RS18670	COG0210	DNA helicase
C0708_RS18680	COG0583	DNA-binding transcription factor activity
C0708_RS18720	COG1280	lysine exporter protein (LysE YggA)
C0708_RS18730	COG2962	Rard protein
C0708_RS18735	COG1012	belongs to the aldehyde dehydrogenase family
C0708_RS18740	COG1396	sequence-specific DNA binding
C0708_RS18755	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C0708_RS18755	COG0519	Catalyzes the synthesis of GMP from XMP
C0708_RS18785	COG1322	Protein conserved in bacteria
C0708_RS18800	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C0708_RS18800	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C0708_RS18805	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C0708_RS18810	COG0242	peptide deformylase activity
C0708_RS18820	COG0758	DNA mediated transformation
C0708_RS18825	COG2922	Belongs to the Smg family
C0708_RS18830	COG0551	DNA topoisomerase type I activity
C0708_RS18835	COG0009	L-threonylcarbamoyladenylate synthase
C0708_RS18840	COG0408	coproporphyrinogen oxidase activity
C0708_RS18845	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C0708_RS18855	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C0708_RS18875	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C0708_RS18880	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C0708_RS18905	COG0174	glutamine synthetase
C0708_RS18910	COG1217	gtp-binding protein TYPA
C0708_RS18915	COG1295	ribonuclease BN
C0708_RS18920	COG1490	D-aminoacyl-tRNA deacylase activity
C0708_RS18940	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C0708_RS18945	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0708_RS18950	COG2610	gluconate transmembrane transporter activity
C0708_RS18955	COG3265	gluconokinase activity
C0708_RS18960	COG0129	dihydroxy-acid dehydratase activity
C0708_RS18965	COG0800	Aldolase
C0708_RS18980	COG1609	Transcriptional regulator
C0708_RS18990	COG4942	peptidase
C0708_RS18995	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C0708_RS19000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C0708_RS19005	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C0708_RS19020	COG0316	Belongs to the HesB IscA family
C0708_RS19020	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C0708_RS19025	COG1040	competence protein
C0708_RS19030	COG0596	Alpha beta hydrolase
C0708_RS19045	COG2183	response to ionizing radiation
C0708_RS19060	COG2205	protein histidine kinase activity
C0708_RS19070	COG0051	transcription antitermination factor activity, RNA binding
C0708_RS19075	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C0708_RS19080	COG0088	Forms part of the polypeptide exit tunnel
C0708_RS19085	COG0089	rRNA binding
C0708_RS19090	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C0708_RS19095	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C0708_RS19100	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C0708_RS19105	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C0708_RS19110	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C0708_RS19115	COG0255	Belongs to the universal ribosomal protein uL29 family
C0708_RS19120	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C0708_RS19125	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C0708_RS19130	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C0708_RS19135	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C0708_RS19140	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C0708_RS19145	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C0708_RS19150	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C0708_RS19155	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C0708_RS19160	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C0708_RS19165	COG1841	ribosomal large subunit assembly
C0708_RS19170	COG0200	Binds to the 23S rRNA
C0708_RS19175	COG0201	protein transport
C0708_RS19180	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C0708_RS19185	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C0708_RS19190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C0708_RS19195	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C0708_RS19200	COG0202	RNA polymerase activity
C0708_RS19205	COG0203	ribosomal protein L17
C0708_RS19260	COG2249	NAD(P)H dehydrogenase (quinone) activity
C0708_RS19265	COG0583	DNA-binding transcription factor activity
C0708_RS19285	COG1770	oligopeptidase
C0708_RS19290	COG2358	TRAP transporter, solute receptor (TAXI family
C0708_RS19305	COG3714	YhhN family
C0708_RS19320	COG0583	DNA-binding transcription factor activity
C0708_RS19330	COG1301	dicarboxylic acid transport
C0708_RS19340	COG2095	MarC family integral membrane protein
C0708_RS19350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C0708_RS19360	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C0708_RS19365	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C0708_RS19390	COG0742	ribosomal rna small subunit methyltransferase
C0708_RS19395	COG0552	protein localization to endoplasmic reticulum
C0708_RS19400	COG2884	Cell division ATP-binding protein ftsE
C0708_RS19405	COG2177	Part of the ABC transporter FtsEX involved in
C0708_RS19415	COG0288	reversible hydration of carbon dioxide
C0708_RS19420	COG2188	Transcriptional regulator
C0708_RS19430	COG0010	Belongs to the arginase family
C0708_RS19435	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C0708_RS19440	COG2986	histidine ammonia-lyase
C0708_RS19505	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0708_RS19510	COG1459	type II secretion system
C0708_RS19520	COG2165	general secretion pathway protein
C0708_RS19530	COG2165	general secretion pathway protein
C0708_RS19560	COG1077	Cell shape determining protein MreB Mrl
C0708_RS19565	COG1792	Involved in formation and maintenance of cell shape
C0708_RS19570	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C0708_RS19575	COG0424	maF-like protein
C0708_RS19590	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0708_RS19595	COG0312	modulator of DNA gyrase
C0708_RS19610	COG0477	Major facilitator Superfamily
C0708_RS19620	COG2321	neutral zinc metallopeptidase
C0708_RS19655	COG0189	ligase activity
C0708_RS19665	COG0745	RESPONSE REGULATOR receiver
C0708_RS19680	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C0708_RS19685	COG0352	thiamine-phosphate diphosphorylase activity
C0708_RS19690	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C0708_RS19700	COG2022	thiamine diphosphate biosynthetic process
C0708_RS19705	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C0708_RS19715	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C0708_RS19735	COG0110	maltose O-acetyltransferase activity
C0708_RS19750	COG3932	Exopolysaccharide synthesis, ExoD
C0708_RS19770	COG1733	regulation of RNA biosynthetic process
C0708_RS19775	COG0456	acetyltransferase
C0708_RS19805	COG1494	fructose-1,6-bisphosphatase
C0708_RS19820	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C0708_RS19825	COG5007	Belongs to the BolA IbaG family
C0708_RS19835	COG2854	intermembrane phospholipid transfer
C0708_RS19840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C0708_RS19845	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C0708_RS19850	COG1127	ABC transporter
C0708_RS19860	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C0708_RS19870	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C0708_RS19875	COG1137	ATPase activity
C0708_RS19880	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C0708_RS19890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0708_RS19895	COG1660	Displays ATPase and GTPase activities
C0708_RS19900	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C0708_RS19920	COG3964	amidohydrolase
C0708_RS19950	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0708_RS19955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C0708_RS19965	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C0708_RS19970	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C0708_RS19975	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C0708_RS19980	COG0723	plastoquinol--plastocyanin reductase activity
C0708_RS19985	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C0708_RS19995	COG0625	glutathione transferase activity
C0708_RS20000	COG2969	positive regulation of protein catabolic process
C0708_RS20005	COG2823	Periplasmic or secreted lipoprotein
C0708_RS20010	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C0708_RS20015	COG0792	nuclease activity
C0708_RS20020	COG3107	peptidoglycan biosynthetic process
C0708_RS20025	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C0708_RS20035	COG2001	Belongs to the MraZ family
C0708_RS20040	COG0275	rRNA processing
C0708_RS20045	COG3116	cell division
C0708_RS20050	COG0768	penicillin binding
C0708_RS20060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C0708_RS20065	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C0708_RS20075	COG0772	Belongs to the SEDS family
C0708_RS20080	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C0708_RS20085	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C0708_RS20095	COG0849	cell division
C0708_RS20100	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C0708_RS20105	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C0708_RS20115	COG0653	protein targeting
C0708_RS20125	COG0494	nUDIX hydrolase
C0708_RS20130	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C0708_RS20135	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C0708_RS20150	COG1459	type II secretion system
C0708_RS20155	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C0708_RS20180	COG2186	Transcriptional regulator
C0708_RS20185	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C0708_RS20190	COG0508	dehydrogenase complex catalyzes the overall conversion of
C0708_RS20195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C0708_RS20205	COG0840	transmembrane signaling receptor activity
C0708_RS20210	COG0840	transmembrane signaling receptor activity
C0708_RS20235	COG1280	lysine exporter protein (LysE YggA)
C0708_RS20245	COG0523	cobalamin synthesis protein
C0708_RS20265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C0708_RS20315	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C0708_RS20325	COG1546	Belongs to the CinA family
C0708_RS20330	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C0708_RS20335	COG2137	regulation of response to DNA damage stimulus
C0708_RS20340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C0708_RS20345	COG0527	aspartate kinase activity
C0708_RS20350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C0708_RS20385	COG1686	Belongs to the peptidase S11 family
C0708_RS20390	COG0586	Pfam SNARE associated Golgi protein
C0708_RS20400	COG0525	valine-tRNA ligase activity
C0708_RS20405	COG2927	DNA polymerase III (CHI subunit)
C0708_RS20410	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C0708_RS20415	COG0795	lipopolysaccharide-transporting ATPase activity
C0708_RS20420	COG0795	lipopolysaccharide-transporting ATPase activity
C0708_RS20435	COG0582	viral genome integration into host DNA
C0708_RS20495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C0708_RS20505	COG2165	general secretion pathway protein
C0708_RS20510	COG0084	hydrolase, TatD family'
C0708_RS20515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0708_RS20525	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C0708_RS20530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C0708_RS20535	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C0708_RS20540	COG0813	purine-nucleoside phosphorylase activity
C0708_RS20545	COG5001	Diguanylate cyclase
C0708_RS20545	COG5002	protein histidine kinase activity
C0708_RS20545	COG3447	MASE1 domain protein
C0708_RS20555	COG0560	Phosphoserine phosphatase
C0708_RS20570	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C0708_RS20580	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C0708_RS20585	COG0776	regulation of translation
C0708_RS20600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C0708_RS20605	COG0735	belongs to the Fur family
C0708_RS20630	COG0513	Belongs to the DEAD box helicase family
C0708_RS20635	COG3022	response to hydroperoxide
C0708_RS20650	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C0708_RS20655	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C0708_RS20660	COG0762	integral membrane protein
C0708_RS20665	COG1872	DUF167
C0708_RS20685	COG3112	Uncharacterised protein family (UPF0231)
C0708_RS20690	COG3835	regulator
C0708_RS20695	COG2610	gluconate transmembrane transporter activity
C0708_RS20700	COG1929	Belongs to the glycerate kinase type-1 family
C0708_RS20715	COG0583	DNA-binding transcription factor activity
C0708_RS20720	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C0708_RS20740	COG1840	ABC-type Fe3 transport system, periplasmic component
C0708_RS20750	COG3842	ATPase activity
C0708_RS20755	COG2837	iron assimilation
C0708_RS20760	COG1438	arginine binding
C0708_RS20765	COG1126	abc transporter atp-binding protein
C0708_RS20770	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C0708_RS20775	COG4215	(ABC) transporter
C0708_RS20780	COG4160	amino acid transport
C0708_RS20785	COG0039	L-malate dehydrogenase activity
C0708_RS20790	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C0708_RS20795	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C0708_RS20795	COG1017	nitric oxide dioxygenase activity
C0708_RS20805	COG4536	flavin adenine dinucleotide binding
C0708_RS20810	COG4137	Cytochrome C assembly protein
C0708_RS20825	COG0228	four-way junction DNA binding
C0708_RS20830	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C0708_RS20835	COG0336	Belongs to the RNA methyltransferase TrmD family
C0708_RS20840	COG0335	large ribosomal subunit rRNA binding
C0708_RS20870	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C0708_RS20875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C0708_RS20880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C0708_RS20890	COG0583	DNA-binding transcription factor activity
C0708_RS20895	COG0640	Transcriptional regulator
C0708_RS20900	COG0268	Binds directly to 16S ribosomal RNA
C0708_RS20905	COG0728	peptidoglycan biosynthetic process
C0708_RS20910	COG0196	riboflavin kinase activity
C0708_RS20915	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C0708_RS20920	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C0708_RS20925	COG1047	Peptidyl-prolyl cis-trans
C0708_RS20930	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C0708_RS20970	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C0708_RS20970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C0708_RS20985	COG1854	S-ribosylhomocysteine lyase activity
C0708_RS20990	COG3706	GGDEF domain
C0708_RS21000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C0708_RS21010	COG2153	protein acetylation
C0708_RS21020	COG1914	H( )-stimulated, divalent metal cation uptake system
C0708_RS21025	COG0360	Binds together with S18 to 16S ribosomal RNA
C0708_RS21030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C0708_RS21035	COG0359	binds to the 23S rRNA
C0708_RS21075	COG1238	metal cluster binding
C0708_RS21080	COG0612	Peptidase, M16
C0708_RS21085	COG2918	glutathione biosynthetic process
C0708_RS21090	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C0708_RS21095	COG1027	Aspartate ammonia-lyase
C0708_RS21100	COG3030	protein affecting phage T7 exclusion by the F plasmid
C0708_RS21110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C0708_RS21115	COG0459	protein refolding
C0708_RS21135	COG0564	pseudouridine synthase activity
C0708_RS21140	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C0708_RS21175	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C0708_RS21185	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C0708_RS21190	COG4208	sulfate ABC transporter
C0708_RS21195	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C0708_RS21200	COG0583	DNA-binding transcription factor activity
C0708_RS21205	COG3397	chitin binding
C0708_RS21245	COG1328	CTP reductase activity
C0708_RS21250	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C0708_RS21290	COG1215	transferase activity, transferring glycosyl groups
C0708_RS21300	COG3118	belongs to the thioredoxin family
C0708_RS21300	COG0457	Tetratricopeptide repeat
C0708_RS21340	COG0840	transmembrane signaling receptor activity
C0708_RS21350	COG4166	transmembrane transport
C0708_RS21365	COG1024	Enoyl-CoA hydratase
C0708_RS21380	COG4221	oxidoreductase activity
C0708_RS21385	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C0708_RS21390	COG0442	prolyl-tRNA aminoacylation
C0708_RS21395	COG0840	transmembrane signaling receptor activity
C0708_RS21400	COG0632	four-way junction helicase activity
C0708_RS21405	COG2255	four-way junction helicase activity
C0708_RS21415	COG1271	oxidase subunit
C0708_RS21420	COG1294	oxidase, subunit
C0708_RS21425	COG4890	Cyd operon protein YbgT
C0708_RS21430	COG3790	cyd operon protein YbgE
C0708_RS21435	COG0824	Thioesterase
C0708_RS21440	COG0811	peptide transport
C0708_RS21460	COG2885	chlorophyll binding
C0708_RS21465	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C0708_RS21540	COG0840	transmembrane signaling receptor activity
C0708_RS21545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C0708_RS21550	COG0676	glucose-6-phosphate 1-epimerase activity
C0708_RS21555	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C0708_RS21560	COG1640	4-alpha-glucanotransferase
C0708_RS21565	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C0708_RS21595	COG2130	NADP-dependent
C0708_RS21600	COG1846	Transcriptional regulator
C0708_RS21630	COG0561	phosphatase activity
C0708_RS21645	COG0733	neurotransmitter:sodium symporter activity
C0708_RS21665	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C0708_RS21680	COG1794	racemase activity, acting on amino acids and derivatives
C0708_RS21690	COG1022	Amp-dependent synthetase and ligase
C0708_RS21700	COG0456	acetyltransferase
C0708_RS21715	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C0708_RS21720	COG5001	Diguanylate cyclase
C0708_RS21720	COG5002	protein histidine kinase activity
C0708_RS21750	COG1902	pentaerythritol trinitrate reductase activity
C0708_RS21765	COG2957	Belongs to the agmatine deiminase family
C0708_RS21805	COG2207	Transcriptional regulator
C0708_RS21805	COG1917	Cupin 2, conserved barrel domain protein
C0708_RS21815	COG0513	Belongs to the DEAD box helicase family
C0708_RS21820	COG2203	Gaf domain
C0708_RS21820	COG2199	diguanylate cyclase activity
C0708_RS21855	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C0708_RS21865	COG0577	efflux transmembrane transporter activity
C0708_RS21865	COG1136	(ABC) transporter
C0708_RS21870	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0708_RS21930	COG1280	lysine exporter protein (LysE YggA)
C0708_RS21935	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C0708_RS21950	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C0708_RS21980	COG0745	RESPONSE REGULATOR receiver
C0708_RS21985	COG3104	oligopeptide transport
C0708_RS21990	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C0708_RS21995	COG1555	photosystem II stabilization
C0708_RS22005	COG2350	Protein conserved in bacteria
C0708_RS22010	COG2917	probably involved in intracellular septation
C0708_RS22015	COG0076	glutamate decarboxylase activity
C0708_RS22025	COG0569	domain protein
C0708_RS22025	COG2985	domain, Protein