locus-tag	class	description
RIMD111065_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
RIMD111065_RS00010	COG0592	DNA-directed DNA polymerase activity
RIMD111065_RS00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RIMD111065_RS00025	COG1196	nuclear chromosome segregation
RIMD111065_RS00075	COG2378	regulation of single-species biofilm formation
RIMD111065_RS00080	COG0071	Belongs to the small heat shock protein (HSP20) family
RIMD111065_RS00085	COG0071	Belongs to the small heat shock protein (HSP20) family
RIMD111065_RS00090	COG3977	Valine--pyruvate aminotransferase
RIMD111065_RS00105	COG2814	Major facilitator Superfamily
RIMD111065_RS00110	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS00115	COG2205	protein histidine kinase activity
RIMD111065_RS00135	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RIMD111065_RS00140	COG4191	Histidine kinase
RIMD111065_RS00140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS00145	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RIMD111065_RS00150	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RIMD111065_RS00155	COG1309	transcriptional regulator
RIMD111065_RS00185	COG0469	pyruvate kinase activity
RIMD111065_RS00190	COG2271	Major facilitator Superfamily
RIMD111065_RS00215	COG0561	phosphatase activity
RIMD111065_RS00220	COG2267	carboxylic ester hydrolase activity
RIMD111065_RS00225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RIMD111065_RS00230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RIMD111065_RS00235	COG1758	RNA polymerase activity
RIMD111065_RS00245	COG0859	PFAM glycosyl transferase family 9
RIMD111065_RS00250	COG3642	lipopolysaccharide core region biosynthetic process
RIMD111065_RS00290	COG0589	response to stress
RIMD111065_RS00295	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RIMD111065_RS00305	COG1528	Iron-storage protein
RIMD111065_RS00310	COG2081	HI0933 family
RIMD111065_RS00315	COG2223	nitrite transmembrane transporter activity
RIMD111065_RS00335	COG3188	usher protein
RIMD111065_RS00355	COG2205	protein histidine kinase activity
RIMD111065_RS00355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS00365	COG3275	phosphorelay sensor kinase activity
RIMD111065_RS00370	COG3279	Response regulator of the LytR AlgR family
RIMD111065_RS00375	COG2223	nitrite transmembrane transporter activity
RIMD111065_RS00380	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
RIMD111065_RS00385	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
RIMD111065_RS00400	COG0583	DNA-binding transcription factor activity
RIMD111065_RS00410	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
RIMD111065_RS00450	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
RIMD111065_RS00455	COG2166	iron-sulfur cluster assembly
RIMD111065_RS00460	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RIMD111065_RS00465	COG0210	DNA helicase
RIMD111065_RS00475	COG3245	cytochrome
RIMD111065_RS00480	COG1063	alcohol dehydrogenase
RIMD111065_RS00485	COG0156	8-amino-7-oxononanoate synthase activity
RIMD111065_RS00495	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RIMD111065_RS00510	COG3306	glycosyltransferase involved in LPS biosynthesis
RIMD111065_RS00530	COG1561	YicC-like family, N-terminal region
RIMD111065_RS00535	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
RIMD111065_RS00540	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
RIMD111065_RS00550	COG0789	Transcriptional regulator
RIMD111065_RS00555	COG4251	negative regulation of phosphorylation
RIMD111065_RS00555	COG3706	GGDEF domain
RIMD111065_RS00555	COG2203	Gaf domain
RIMD111065_RS00555	COG5001	Diguanylate cyclase
RIMD111065_RS00560	COG3084	Protein conserved in bacteria
RIMD111065_RS00570	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
RIMD111065_RS00575	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RIMD111065_RS00580	COG3639	organic phosphonate transmembrane transporter activity
RIMD111065_RS00585	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
RIMD111065_RS00590	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
RIMD111065_RS00600	COG1335	isochorismatase
RIMD111065_RS00610	COG1683	Conserved Protein
RIMD111065_RS00615	COG0204	Acyl-transferase
RIMD111065_RS00620	COG0204	Acyl-transferase
RIMD111065_RS00625	COG0606	chelatase, subunit chli
RIMD111065_RS00635	COG3978	acetolactate synthase activity
RIMD111065_RS00645	COG0129	dihydroxy-acid dehydratase activity
RIMD111065_RS00665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
RIMD111065_RS00670	COG0254	rRNA binding
RIMD111065_RS00675	COG0702	epimerase
RIMD111065_RS00680	COG0281	malic enzyme
RIMD111065_RS00690	COG2205	protein histidine kinase activity
RIMD111065_RS00695	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS00700	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RIMD111065_RS00715	COG0366	Alpha amylase catalytic
RIMD111065_RS00730	COG0443	Heat shock 70 kDa protein
RIMD111065_RS00735	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RIMD111065_RS00740	COG3045	CreA protein
RIMD111065_RS00760	COG0174	glutamine synthetase
RIMD111065_RS00780	COG3842	ATPase activity
RIMD111065_RS00785	COG1176	ABC-type spermidine putrescine transport system, permease component I
RIMD111065_RS00790	COG1177	transmembrane transport
RIMD111065_RS00795	COG2258	MOSC domain
RIMD111065_RS00810	COG2050	protein possibly involved in aromatic compounds catabolism
RIMD111065_RS00815	COG0514	ATP-dependent DNA helicase (RecQ)
RIMD111065_RS00825	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
RIMD111065_RS00835	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
RIMD111065_RS00840	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RIMD111065_RS00850	COG2239	Acts as a magnesium transporter
RIMD111065_RS00855	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RIMD111065_RS00855	COG1648	precorrin-2 dehydrogenase activity
RIMD111065_RS00860	COG2116	formate transmembrane transporter activity
RIMD111065_RS00870	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RIMD111065_RS00880	COG0477	Major facilitator Superfamily
RIMD111065_RS00885	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
RIMD111065_RS00890	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
RIMD111065_RS00910	COG1595	DNA-templated transcription, initiation
RIMD111065_RS00915	COG3806	Anti-sigma factor
RIMD111065_RS00920	COG1968	undecaprenyl-diphosphatase activity
RIMD111065_RS00925	COG0667	Aldo Keto reductase
RIMD111065_RS00930	COG2017	converts alpha-aldose to the beta-anomer
RIMD111065_RS00935	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
RIMD111065_RS00945	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RIMD111065_RS00950	COG1609	Transcriptional regulator
RIMD111065_RS00955	COG3250	beta-galactosidase activity
RIMD111065_RS01005	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RIMD111065_RS01010	COG1288	antiporter activity
RIMD111065_RS01015	COG1438	arginine binding
RIMD111065_RS01020	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
RIMD111065_RS01025	COG0540	Belongs to the ATCase OTCase family
RIMD111065_RS01045	COG0688	phosphatidylethanolamine metabolic process
RIMD111065_RS01055	COG3040	lipid binding
RIMD111065_RS01060	COG2207	Transcriptional regulator
RIMD111065_RS01065	COG1979	alcohol dehydrogenase
RIMD111065_RS01070	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
RIMD111065_RS01075	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
RIMD111065_RS01085	COG3681	Belongs to the UPF0597 family
RIMD111065_RS01095	COG0446	pyridine nucleotide-disulphide oxidoreductase
RIMD111065_RS01100	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RIMD111065_RS01105	COG0564	pseudouridine synthase activity
RIMD111065_RS01115	COG0542	response to heat
RIMD111065_RS01120	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
RIMD111065_RS01125	COG2502	aspartate--ammonia ligase
RIMD111065_RS01130	COG1522	sequence-specific DNA binding
RIMD111065_RS01140	COG5413	integral membrane protein
RIMD111065_RS01150	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS01165	COG2205	protein histidine kinase activity
RIMD111065_RS01175	COG2204	response regulator
RIMD111065_RS01190	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
RIMD111065_RS01220	COG0243	molybdopterin cofactor binding
RIMD111065_RS01225	COG3005	denitrification pathway
RIMD111065_RS01230	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
RIMD111065_RS01250	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RIMD111065_RS01255	COG0569	domain protein
RIMD111065_RS01260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
RIMD111065_RS01285	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RIMD111065_RS01300	COG0250	Participates in transcription elongation, termination and antitermination
RIMD111065_RS01305	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
RIMD111065_RS01310	COG0081	regulation of translation
RIMD111065_RS01315	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
RIMD111065_RS01320	COG0222	ribosome binding
RIMD111065_RS01325	COG0085	RNA polymerase activity
RIMD111065_RS01330	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
RIMD111065_RS01335	COG2964	Protein conserved in bacteria
RIMD111065_RS01340	COG0251	oxidation-reduction process
RIMD111065_RS01350	COG2923	Belongs to the DsrF TusC family
RIMD111065_RS01355	COG2168	tRNA wobble position uridine thiolation
RIMD111065_RS01360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
RIMD111065_RS01365	COG0049	tRNA binding
RIMD111065_RS01370	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
RIMD111065_RS01375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
RIMD111065_RS01380	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RIMD111065_RS01415	COG2252	PERMEase
RIMD111065_RS01420	COG2376	Dihydroxyacetone kinase
RIMD111065_RS01425	COG1461	Dihydroxyacetone kinase
RIMD111065_RS01440	COG3284	Transcriptional regulator
RIMD111065_RS01450	COG2957	Belongs to the agmatine deiminase family
RIMD111065_RS01460	COG0628	permease
RIMD111065_RS01465	COG0494	nUDIX hydrolase
RIMD111065_RS01490	COG0753	catalase activity
RIMD111065_RS01495	COG1247	-acetyltransferase
RIMD111065_RS01515	COG2199	diguanylate cyclase activity
RIMD111065_RS01515	COG2203	Gaf domain
RIMD111065_RS01525	COG3842	ATPase activity
RIMD111065_RS01535	COG1175	transmembrane transport
RIMD111065_RS01560	COG0583	DNA-binding transcription factor activity
RIMD111065_RS01570	COG1741	Belongs to the pirin family
RIMD111065_RS01575	COG2259	Doxx family
RIMD111065_RS01580	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
RIMD111065_RS01585	COG1074	ATP-dependent DNA helicase activity
RIMD111065_RS01590	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
RIMD111065_RS01600	COG0346	lactoylglutathione lyase activity
RIMD111065_RS01650	COG3706	GGDEF domain
RIMD111065_RS01655	COG4771	TonB-dependent receptor
RIMD111065_RS01660	COG1278	Cold shock
RIMD111065_RS01680	COG0629	single-stranded DNA binding
RIMD111065_RS01685	COG2197	response regulator
RIMD111065_RS01690	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
RIMD111065_RS01700	COG3047	cAMP biosynthetic process
RIMD111065_RS01705	COG0840	transmembrane signaling receptor activity
RIMD111065_RS01730	COG3135	benzoate transporter
RIMD111065_RS01735	COG1396	sequence-specific DNA binding
RIMD111065_RS01765	COG2926	Belongs to the UPF0265 family
RIMD111065_RS01775	COG3028	Belongs to the UPF0307 family
RIMD111065_RS01780	COG0312	modulator of DNA gyrase
RIMD111065_RS01785	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
RIMD111065_RS01790	COG5007	Belongs to the BolA IbaG family
RIMD111065_RS01800	COG2854	intermembrane phospholipid transfer
RIMD111065_RS01805	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RIMD111065_RS01810	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
RIMD111065_RS01815	COG1127	ABC transporter
RIMD111065_RS01820	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RIMD111065_RS01820	COG0517	IMP dehydrogenase activity
RIMD111065_RS01825	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
RIMD111065_RS01830	COG3117	lipopolysaccharide transmembrane transporter activity
RIMD111065_RS01835	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
RIMD111065_RS01840	COG1137	ATPase activity
RIMD111065_RS01845	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
RIMD111065_RS01855	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS01860	COG1660	Displays ATPase and GTPase activities
RIMD111065_RS01865	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS01870	COG3711	transcriptional antiterminator
RIMD111065_RS01870	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS01885	COG3964	amidohydrolase
RIMD111065_RS01915	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RIMD111065_RS01920	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
RIMD111065_RS01930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
RIMD111065_RS01935	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
RIMD111065_RS01940	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
RIMD111065_RS01945	COG0723	plastoquinol--plastocyanin reductase activity
RIMD111065_RS01950	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
RIMD111065_RS01955	COG2857	Cytochrome c1
RIMD111065_RS01960	COG0625	glutathione transferase activity
RIMD111065_RS01965	COG2969	positive regulation of protein catabolic process
RIMD111065_RS01970	COG2823	Periplasmic or secreted lipoprotein
RIMD111065_RS01975	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RIMD111065_RS01980	COG0792	nuclease activity
RIMD111065_RS01985	COG3107	peptidoglycan biosynthetic process
RIMD111065_RS01990	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
RIMD111065_RS02000	COG2001	Belongs to the MraZ family
RIMD111065_RS02005	COG0275	rRNA processing
RIMD111065_RS02010	COG3116	cell division
RIMD111065_RS02015	COG0768	penicillin binding
RIMD111065_RS02025	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
RIMD111065_RS02030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RIMD111065_RS02035	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
RIMD111065_RS02040	COG0772	Belongs to the SEDS family
RIMD111065_RS02045	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RIMD111065_RS02050	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RIMD111065_RS02055	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
RIMD111065_RS02060	COG0849	cell division
RIMD111065_RS02065	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
RIMD111065_RS02070	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
RIMD111065_RS02080	COG0653	protein targeting
RIMD111065_RS02090	COG0494	nUDIX hydrolase
RIMD111065_RS02095	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
RIMD111065_RS02100	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
RIMD111065_RS02115	COG1459	type II secretion system
RIMD111065_RS02120	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RIMD111065_RS02145	COG2186	Transcriptional regulator
RIMD111065_RS02150	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
RIMD111065_RS02155	COG0508	dehydrogenase complex catalyzes the overall conversion of
RIMD111065_RS02160	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
RIMD111065_RS02170	COG0840	transmembrane signaling receptor activity
RIMD111065_RS02175	COG0840	transmembrane signaling receptor activity
RIMD111065_RS02180	COG1752	Esterase of the alpha-beta hydrolase superfamily
RIMD111065_RS02185	COG1049	propionate catabolic process, 2-methylcitrate cycle
RIMD111065_RS02190	COG2200	EAL domain
RIMD111065_RS02200	COG1280	lysine exporter protein (LysE YggA)
RIMD111065_RS02210	COG0523	cobalamin synthesis protein
RIMD111065_RS02215	COG0477	Major facilitator Superfamily
RIMD111065_RS02230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
RIMD111065_RS02235	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
RIMD111065_RS02275	COG3314	Sporulation integral membrane protein YlbJ
RIMD111065_RS02280	COG0835	chemotaxis
RIMD111065_RS02280	COG0784	Response regulator, receiver
RIMD111065_RS02285	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS02290	COG1444	tRNA N-acetyltransferase activity
RIMD111065_RS02315	COG1803	Methylglyoxal synthase
RIMD111065_RS02330	COG0252	asparaginase activity
RIMD111065_RS02350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS02350	COG1263	PTS System
RIMD111065_RS02355	COG0366	Alpha amylase catalytic
RIMD111065_RS02360	COG0110	maltose O-acetyltransferase activity
RIMD111065_RS02365	COG1522	sequence-specific DNA binding
RIMD111065_RS02370	COG5006	permease, DMT superfamily
RIMD111065_RS02380	COG1012	belongs to the aldehyde dehydrogenase family
RIMD111065_RS02385	COG1177	transmembrane transport
RIMD111065_RS02390	COG1176	ABC-type spermidine putrescine transport system, permease component I
RIMD111065_RS02395	COG3842	ATPase activity
RIMD111065_RS02400	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
RIMD111065_RS02405	COG0583	DNA-binding transcription factor activity
RIMD111065_RS02410	COG1757	Na H antiporter
RIMD111065_RS02450	COG0297	glycogen (starch) synthase activity
RIMD111065_RS02455	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RIMD111065_RS02460	COG2813	Specifically methylates the guanine in position
RIMD111065_RS02465	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RIMD111065_RS02470	COG5001	Diguanylate cyclase
RIMD111065_RS02470	COG4251	negative regulation of phosphorylation
RIMD111065_RS02470	COG2203	Gaf domain
RIMD111065_RS02470	COG3706	GGDEF domain
RIMD111065_RS02480	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RIMD111065_RS02490	COG2995	paraquat-inducible protein a
RIMD111065_RS02495	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
RIMD111065_RS02495	COG3008	intermembrane lipid transfer
RIMD111065_RS02500	COG3009	Protein conserved in bacteria
RIMD111065_RS02505	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
RIMD111065_RS02505	COG2885	chlorophyll binding
RIMD111065_RS02515	COG3240	lipase activity
RIMD111065_RS02520	COG3111	PFAM Bacterial OB fold (BOF) protein
RIMD111065_RS02530	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
RIMD111065_RS02535	COG1194	a g-specific adenine glycosylase
RIMD111065_RS02545	COG3409	Peptidoglycan-binding domain 1 protein
RIMD111065_RS02545	COG3267	Type II secretory pathway component ExeA
RIMD111065_RS02550	COG0617	tRNA 3'-terminal CCA addition
RIMD111065_RS02565	COG1346	cytolysis
RIMD111065_RS02570	COG1380	Effector of murein hydrolase LrgA
RIMD111065_RS02575	COG0583	DNA-binding transcription factor activity
RIMD111065_RS02605	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
RIMD111065_RS02610	COG0306	phosphate transporter
RIMD111065_RS02615	COG1392	Phosphate transport regulator
RIMD111065_RS02620	COG3025	triphosphatase activity
RIMD111065_RS02630	COG1560	Kdo2-lipid A biosynthetic process
RIMD111065_RS02635	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
RIMD111065_RS02635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
RIMD111065_RS02640	COG1538	Outer membrane efflux protein
RIMD111065_RS02645	COG0494	nUDIX hydrolase
RIMD111065_RS02650	COG3151	Protein conserved in bacteria
RIMD111065_RS02660	COG3150	esterase
RIMD111065_RS02665	COG1051	belongs to the nudix hydrolase family
RIMD111065_RS02680	COG1566	PFAM secretion protein HlyD family protein
RIMD111065_RS02685	COG1289	transmembrane transporter activity
RIMD111065_RS02705	COG0583	DNA-binding transcription factor activity
RIMD111065_RS02745	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RIMD111065_RS02765	COG0204	Acyl-transferase
RIMD111065_RS02770	COG1842	Phage shock protein A
RIMD111065_RS02785	COG2827	Endonuclease containing a URI domain
RIMD111065_RS02795	COG2962	Rard protein
RIMD111065_RS02800	COG1573	uracil-dna glycosylase
RIMD111065_RS02805	COG0697	spore germination
RIMD111065_RS02810	COG0583	DNA-binding transcription factor activity
RIMD111065_RS02815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
RIMD111065_RS02820	COG1121	(ABC) transporter
RIMD111065_RS02825	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
RIMD111065_RS02845	COG0739	heme binding
RIMD111065_RS02855	COG3068	Protein conserved in bacteria
RIMD111065_RS02875	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
RIMD111065_RS02880	COG1546	Belongs to the CinA family
RIMD111065_RS02885	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
RIMD111065_RS02895	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
RIMD111065_RS02900	COG0527	aspartate kinase activity
RIMD111065_RS02905	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
RIMD111065_RS02940	COG1686	Belongs to the peptidase S11 family
RIMD111065_RS02945	COG0586	Pfam SNARE associated Golgi protein
RIMD111065_RS02950	COG1253	flavin adenine dinucleotide binding
RIMD111065_RS02955	COG0525	valine-tRNA ligase activity
RIMD111065_RS02960	COG2927	DNA polymerase III (CHI subunit)
RIMD111065_RS02965	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RIMD111065_RS02970	COG0795	lipopolysaccharide-transporting ATPase activity
RIMD111065_RS02975	COG0795	lipopolysaccharide-transporting ATPase activity
RIMD111065_RS02990	COG0004	ammonium transporteR
RIMD111065_RS02995	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RIMD111065_RS03005	COG2165	general secretion pathway protein
RIMD111065_RS03010	COG0084	hydrolase, TatD family'
RIMD111065_RS03015	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RIMD111065_RS03025	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RIMD111065_RS03030	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
RIMD111065_RS03035	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
RIMD111065_RS03040	COG0813	purine-nucleoside phosphorylase activity
RIMD111065_RS03045	COG5002	protein histidine kinase activity
RIMD111065_RS03045	COG5001	Diguanylate cyclase
RIMD111065_RS03045	COG3447	MASE1 domain protein
RIMD111065_RS03055	COG0560	Phosphoserine phosphatase
RIMD111065_RS03080	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
RIMD111065_RS03090	COG0776	regulation of translation
RIMD111065_RS03105	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RIMD111065_RS03110	COG0735	belongs to the Fur family
RIMD111065_RS03135	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
RIMD111065_RS03140	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS03145	COG3022	response to hydroperoxide
RIMD111065_RS03160	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
RIMD111065_RS03165	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
RIMD111065_RS03170	COG0762	integral membrane protein
RIMD111065_RS03175	COG1872	DUF167
RIMD111065_RS03190	COG4166	transmembrane transport
RIMD111065_RS03210	COG1024	Enoyl-CoA hydratase
RIMD111065_RS03225	COG4221	oxidoreductase activity
RIMD111065_RS03230	COG0442	prolyl-tRNA aminoacylation
RIMD111065_RS03235	COG0840	transmembrane signaling receptor activity
RIMD111065_RS03240	COG0632	four-way junction helicase activity
RIMD111065_RS03245	COG2255	four-way junction helicase activity
RIMD111065_RS03250	COG1271	oxidase subunit
RIMD111065_RS03255	COG1294	oxidase, subunit
RIMD111065_RS03260	COG4890	Cyd operon protein YbgT
RIMD111065_RS03265	COG3790	cyd operon protein YbgE
RIMD111065_RS03270	COG0824	Thioesterase
RIMD111065_RS03275	COG0811	peptide transport
RIMD111065_RS03290	COG0823	Involved in the tonB-independent uptake of proteins
RIMD111065_RS03295	COG2885	chlorophyll binding
RIMD111065_RS03300	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
RIMD111065_RS03375	COG0840	transmembrane signaling receptor activity
RIMD111065_RS03380	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
RIMD111065_RS03385	COG0676	glucose-6-phosphate 1-epimerase activity
RIMD111065_RS03390	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RIMD111065_RS03395	COG1640	4-alpha-glucanotransferase
RIMD111065_RS03400	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
RIMD111065_RS03420	COG1051	belongs to the nudix hydrolase family
RIMD111065_RS03425	COG2130	NADP-dependent
RIMD111065_RS03430	COG1764	response to oxidative stress
RIMD111065_RS03435	COG1846	Transcriptional regulator
RIMD111065_RS03470	COG0561	phosphatase activity
RIMD111065_RS03485	COG0733	neurotransmitter:sodium symporter activity
RIMD111065_RS03495	COG0733	neurotransmitter:sodium symporter activity
RIMD111065_RS03520	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RIMD111065_RS03535	COG1794	racemase activity, acting on amino acids and derivatives
RIMD111065_RS03550	COG2731	YhcH YjgK YiaL family protein
RIMD111065_RS03560	COG0668	transmembrane transport
RIMD111065_RS03570	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RIMD111065_RS03615	COG0583	DNA-binding transcription factor activity
RIMD111065_RS03620	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
RIMD111065_RS03630	COG0488	(ABC) transporter
RIMD111065_RS03635	COG0517	IMP dehydrogenase activity
RIMD111065_RS03635	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
RIMD111065_RS03640	COG1585	Membrane protein implicated in regulation of membrane protease activity
RIMD111065_RS03645	COG0330	HflC and HflK could
RIMD111065_RS03650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RIMD111065_RS03650	COG1648	precorrin-2 dehydrogenase activity
RIMD111065_RS03655	COG0175	sulfate reduction
RIMD111065_RS03660	COG2895	sulfate adenylyltransferase (ATP) activity
RIMD111065_RS03665	COG3273	potassium ion transport
RIMD111065_RS03665	COG0471	metal ion transport
RIMD111065_RS03670	COG0529	Catalyzes the synthesis of activated sulfate
RIMD111065_RS03710	COG1136	(ABC) transporter
RIMD111065_RS03725	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
RIMD111065_RS03740	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
RIMD111065_RS03745	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
RIMD111065_RS03750	COG0163	prenyltransferase activity
RIMD111065_RS03765	COG1131	(ABC) transporter
RIMD111065_RS03770	COG0842	Transport permease protein
RIMD111065_RS03775	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
RIMD111065_RS03780	COG1924	4 iron, 4 sulfur cluster binding
RIMD111065_RS03800	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
RIMD111065_RS03805	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
RIMD111065_RS03820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RIMD111065_RS03825	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
RIMD111065_RS03830	COG1489	DNA binding
RIMD111065_RS03840	COG1643	Atp-dependent helicase
RIMD111065_RS03845	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RIMD111065_RS03850	COG0346	lactoylglutathione lyase activity
RIMD111065_RS03860	COG2076	Multidrug Resistance protein
RIMD111065_RS03870	COG0784	Response regulator, receiver
RIMD111065_RS03870	COG3437	response regulator, receiver
RIMD111065_RS03880	COG0671	phosphoesterase, PA-phosphatase related
RIMD111065_RS03895	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RIMD111065_RS03900	COG0038	chloride channel
RIMD111065_RS03910	COG0316	Belongs to the HesB IscA family
RIMD111065_RS03935	COG1280	lysine exporter protein (LysE YggA)
RIMD111065_RS03950	COG3311	Transcriptional regulator
RIMD111065_RS03995	COG2003	Belongs to the UPF0758 family
RIMD111065_RS04045	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
RIMD111065_RS04050	COG0732	type I restriction modification DNA specificity domain
RIMD111065_RS04055	COG1401	restriction endodeoxyribonuclease activity
RIMD111065_RS04055	COG1401	restriction endodeoxyribonuclease activity
RIMD111065_RS04065	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
RIMD111065_RS04075	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
RIMD111065_RS04090	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RIMD111065_RS04120	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS04125	COG3104	oligopeptide transport
RIMD111065_RS04130	COG1210	Utp--glucose-1-phosphate uridylyltransferase
RIMD111065_RS04135	COG1555	photosystem II stabilization
RIMD111065_RS04145	COG2350	Protein conserved in bacteria
RIMD111065_RS04150	COG2917	probably involved in intracellular septation
RIMD111065_RS04155	COG0076	glutamate decarboxylase activity
RIMD111065_RS04160	COG1272	protein, Hemolysin III
RIMD111065_RS04165	COG2985	domain, Protein
RIMD111065_RS04165	COG0569	domain protein
RIMD111065_RS04175	COG0835	chemotaxis
RIMD111065_RS04175	COG0784	Response regulator, receiver
RIMD111065_RS04180	COG2755	lipolytic protein G-D-S-L family
RIMD111065_RS04185	COG4181	ATPase activity
RIMD111065_RS04190	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
RIMD111065_RS04195	COG1090	epimerase
RIMD111065_RS04200	COG2200	EAL domain
RIMD111065_RS04205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RIMD111065_RS04210	COG4935	Belongs to the peptidase S8 family
RIMD111065_RS04210	COG2234	aminopeptidase activity
RIMD111065_RS04215	COG0220	tRNA (guanine-N7-)-methyltransferase activity
RIMD111065_RS04220	COG3171	Protein conserved in bacteria
RIMD111065_RS04225	COG2066	Belongs to the glutaminase family
RIMD111065_RS04230	COG2897	thiosulfate sulfurtransferase activity
RIMD111065_RS04235	COG1404	Belongs to the peptidase S8 family
RIMD111065_RS04245	COG1132	(ABC) transporter
RIMD111065_RS04270	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
RIMD111065_RS04275	COG3300	MHYT domain
RIMD111065_RS04275	COG5001	Diguanylate cyclase
RIMD111065_RS04285	COG2207	Transcriptional regulator
RIMD111065_RS04290	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RIMD111065_RS04295	COG3059	membrane
RIMD111065_RS04310	COG4628	conserved protein (DUF2132)
RIMD111065_RS04315	COG0688	phosphatidylethanolamine metabolic process
RIMD111065_RS04320	COG1162	GTPase activity
RIMD111065_RS04325	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
RIMD111065_RS04365	COG1278	Cold shock
RIMD111065_RS04375	COG0840	transmembrane signaling receptor activity
RIMD111065_RS04380	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RIMD111065_RS04385	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RIMD111065_RS04440	COG0848	biopolymer transport protein
RIMD111065_RS04445	COG0811	peptide transport
RIMD111065_RS04450	COG0811	peptide transport
RIMD111065_RS04465	COG4174	ABC transporter (Permease)
RIMD111065_RS04470	COG4239	(ABC) transporter, permease
RIMD111065_RS04480	COG0444	Belongs to the ABC transporter superfamily
RIMD111065_RS04485	COG4608	Belongs to the ABC transporter superfamily
RIMD111065_RS04490	COG2195	Cleaves the N-terminal amino acid of tripeptides
RIMD111065_RS04495	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
RIMD111065_RS04500	COG1073	alpha beta
RIMD111065_RS04515	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
RIMD111065_RS04545	COG0243	molybdopterin cofactor binding
RIMD111065_RS04560	COG1116	anion transmembrane transporter activity
RIMD111065_RS04560	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
RIMD111065_RS04565	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
RIMD111065_RS04570	COG1116	anion transmembrane transporter activity
RIMD111065_RS04575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RIMD111065_RS04575	COG2146	nitrite reductase [NAD(P)H] activity
RIMD111065_RS04580	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RIMD111065_RS04580	COG2146	nitrite reductase [NAD(P)H] activity
RIMD111065_RS04585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RIMD111065_RS04590	COG2313	pseudouridylate synthase activity
RIMD111065_RS04595	COG2313	pseudouridylate synthase activity
RIMD111065_RS04605	COG1858	cytochrome C peroxidase
RIMD111065_RS04640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RIMD111065_RS04645	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RIMD111065_RS04695	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RIMD111065_RS04705	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS04710	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RIMD111065_RS04720	COG0521	Mo-molybdopterin cofactor biosynthetic process
RIMD111065_RS04730	COG2966	Psort location CytoplasmicMembrane, score
RIMD111065_RS04735	COG3610	response to peptide
RIMD111065_RS04745	COG4175	Glycine betaine
RIMD111065_RS04750	COG4176	ABC-type proline glycine betaine transport system permease component
RIMD111065_RS04755	COG2113	Glycine betaine
RIMD111065_RS04760	COG0175	sulfate reduction
RIMD111065_RS04765	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
RIMD111065_RS04770	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RIMD111065_RS04775	COG0384	phenazine biosynthesis protein PhzF
RIMD111065_RS04780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
RIMD111065_RS04795	COG0786	glutamate:sodium symporter activity
RIMD111065_RS04800	COG0252	asparaginase activity
RIMD111065_RS04805	COG3139	Protein of unknown function (DUF1315)
RIMD111065_RS04825	COG0616	signal peptide processing
RIMD111065_RS04830	COG0446	pyridine nucleotide-disulphide oxidoreductase
RIMD111065_RS04830	COG1902	pentaerythritol trinitrate reductase activity
RIMD111065_RS04835	COG0778	Nitroreductase
RIMD111065_RS04850	COG2264	protein methyltransferase activity
RIMD111065_RS04855	COG0604	alcohol dehydrogenase
RIMD111065_RS04860	COG0583	DNA-binding transcription factor activity
RIMD111065_RS04865	COG1263	PTS System
RIMD111065_RS04865	COG2190	(PTS) system
RIMD111065_RS04865	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS04870	COG4145	pantothenate transmembrane transporter activity
RIMD111065_RS04880	COG0439	Biotin carboxylase
RIMD111065_RS04885	COG0511	ligase activity, forming carbon-carbon bonds
RIMD111065_RS04890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
RIMD111065_RS04895	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RIMD111065_RS04905	COG5001	Diguanylate cyclase
RIMD111065_RS04905	COG3300	MHYT domain
RIMD111065_RS04925	COG3381	protein complex oligomerization
RIMD111065_RS04940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
RIMD111065_RS04950	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
RIMD111065_RS04955	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RIMD111065_RS04955	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
RIMD111065_RS04970	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
RIMD111065_RS04975	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RIMD111065_RS04980	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
RIMD111065_RS04985	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
RIMD111065_RS04990	COG4172	Belongs to the ABC transporter superfamily
RIMD111065_RS05000	COG0601	transmembrane transport
RIMD111065_RS05010	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
RIMD111065_RS05015	COG0142	geranyltranstransferase activity
RIMD111065_RS05020	COG1722	exodeoxyribonuclease VII activity
RIMD111065_RS05025	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RIMD111065_RS05030	COG1360	Flagellar Motor Protein
RIMD111065_RS05045	COG1534	Rna-binding protein
RIMD111065_RS05050	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
RIMD111065_RS05060	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
RIMD111065_RS05065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
RIMD111065_RS05070	COG0149	triose-phosphate isomerase activity
RIMD111065_RS05075	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
RIMD111065_RS05090	COG0779	Required for maturation of 30S ribosomal subunits
RIMD111065_RS05095	COG0195	Participates in both transcription termination and antitermination
RIMD111065_RS05100	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
RIMD111065_RS05105	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
RIMD111065_RS05110	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
RIMD111065_RS05115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
RIMD111065_RS05120	COG1185	polyribonucleotide nucleotidyltransferase activity
RIMD111065_RS05125	COG2211	Major facilitator Superfamily
RIMD111065_RS05135	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
RIMD111065_RS05145	COG0114	fumarate hydratase activity
RIMD111065_RS05155	COG1966	Carbon starvation protein
RIMD111065_RS05160	COG3279	Response regulator of the LytR AlgR family
RIMD111065_RS05165	COG3275	phosphorelay sensor kinase activity
RIMD111065_RS05230	COG0312	modulator of DNA gyrase
RIMD111065_RS05235	COG0312	modulator of DNA gyrase
RIMD111065_RS05245	COG4974	Belongs to the 'phage' integrase family
RIMD111065_RS05255	COG1970	mechanosensitive ion channel activity
RIMD111065_RS05260	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RIMD111065_RS05275	COG0789	Transcriptional regulator
RIMD111065_RS05290	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
RIMD111065_RS05295	COG0596	Alpha beta hydrolase
RIMD111065_RS05305	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
RIMD111065_RS05310	COG0321	lipoyl(octanoyl) transferase activity
RIMD111065_RS05315	COG2921	Belongs to the UPF0250 family
RIMD111065_RS05320	COG1686	Belongs to the peptidase S11 family
RIMD111065_RS05325	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
RIMD111065_RS05330	COG2951	lytic endotransglycosylase activity
RIMD111065_RS05335	COG0772	Belongs to the SEDS family
RIMD111065_RS05340	COG0768	penicillin binding
RIMD111065_RS05345	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
RIMD111065_RS05350	COG0799	negative regulation of ribosome biogenesis
RIMD111065_RS05355	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
RIMD111065_RS05375	COG0495	leucyl-tRNA aminoacylation
RIMD111065_RS05380	COG2888	peptidyl-tyrosine sulfation
RIMD111065_RS05385	COG0815	Transfers the fatty acyl group on membrane lipoproteins
RIMD111065_RS05390	COG4535	Mg2 and Co2 transporter CorC
RIMD111065_RS05395	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
RIMD111065_RS05400	COG1702	phosphate starvation-inducible protein PhoH
RIMD111065_RS05405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RIMD111065_RS05410	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RIMD111065_RS05415	COG1335	isochorismatase
RIMD111065_RS05425	COG3706	GGDEF domain
RIMD111065_RS05440	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RIMD111065_RS05450	COG3706	GGDEF domain
RIMD111065_RS05460	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
RIMD111065_RS05470	COG3647	Membrane
RIMD111065_RS05475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
RIMD111065_RS05485	COG0516	GMP reductase activity
RIMD111065_RS05495	COG0642	Histidine kinase
RIMD111065_RS05535	COG3214	Protein conserved in bacteria
RIMD111065_RS05560	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
RIMD111065_RS05565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
RIMD111065_RS05570	COG1053	succinate dehydrogenase
RIMD111065_RS05580	COG0584	glycerophosphoryl diester phosphodiesterase
RIMD111065_RS05585	COG1511	domain protein
RIMD111065_RS05585	COG3264	Mechanosensitive ion channel
RIMD111065_RS05595	COG0739	heme binding
RIMD111065_RS05610	COG0583	DNA-binding transcription factor activity
RIMD111065_RS05630	COG0583	DNA-binding transcription factor activity
RIMD111065_RS05635	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
RIMD111065_RS05665	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RIMD111065_RS05670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
RIMD111065_RS05680	COG0338	D12 class N6 adenine-specific DNA methyltransferase
RIMD111065_RS05685	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
RIMD111065_RS05695	COG0180	Tryptophanyl-tRNA synthetase
RIMD111065_RS05710	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
RIMD111065_RS05720	COG1012	belongs to the aldehyde dehydrogenase family
RIMD111065_RS05730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RIMD111065_RS05740	COG1013	pyruvate-flavodoxin oxidoreductase activity
RIMD111065_RS05740	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RIMD111065_RS05740	COG0674	pyruvate-flavodoxin oxidoreductase activity
RIMD111065_RS05740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RIMD111065_RS05750	COG0366	Alpha amylase catalytic
RIMD111065_RS05770	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
RIMD111065_RS05780	COG0490	domain, Protein
RIMD111065_RS05780	COG0471	metal ion transport
RIMD111065_RS05835	COG1349	DNA-binding transcription factor activity
RIMD111065_RS05845	COG2222	sugar isomerase
RIMD111065_RS05850	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RIMD111065_RS05860	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS05865	COG3715	PTS system
RIMD111065_RS05870	COG3716	PTS system mannose fructose sorbose family IID component
RIMD111065_RS05885	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS05895	COG0641	radical SAM
RIMD111065_RS05900	COG3119	arylsulfatase activity
RIMD111065_RS05910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RIMD111065_RS05915	COG0800	Aldolase
RIMD111065_RS05925	COG3119	arylsulfatase activity
RIMD111065_RS05930	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RIMD111065_RS05940	COG2003	Belongs to the UPF0758 family
RIMD111065_RS05950	COG0012	GTP binding
RIMD111065_RS05955	COG0193	aminoacyl-tRNA hydrolase activity
RIMD111065_RS05960	COG0737	Belongs to the 5'-nucleotidase family
RIMD111065_RS05965	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
RIMD111065_RS05975	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
RIMD111065_RS05980	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
RIMD111065_RS05985	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
RIMD111065_RS05990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
RIMD111065_RS05995	COG2890	protein-(glutamine-N5) methyltransferase activity
RIMD111065_RS06005	COG2912	Transglutaminase-like superfamily
RIMD111065_RS06010	COG2877	3-deoxy-8-phosphooctulonate synthase activity
RIMD111065_RS06015	COG1301	dicarboxylic acid transport
RIMD111065_RS06025	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
RIMD111065_RS06040	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RIMD111065_RS06045	COG1115	amino acid carrier protein
RIMD111065_RS06060	COG0714	Associated with various cellular activities
RIMD111065_RS06085	COG3104	oligopeptide transport
RIMD111065_RS06090	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
RIMD111065_RS06095	COG1678	Uncharacterized ACR, COG1678
RIMD111065_RS06105	COG0189	ligase activity
RIMD111065_RS06110	COG1385	rRNA (uridine-N3-)-methyltransferase activity
RIMD111065_RS06120	COG3091	SprT-like family
RIMD111065_RS06130	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
RIMD111065_RS06150	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
RIMD111065_RS06155	COG0739	heme binding
RIMD111065_RS06160	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RIMD111065_RS06165	COG3408	Glycogen debranching enzyme
RIMD111065_RS06165	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
RIMD111065_RS06175	COG1881	PFAM PEBP family protein
RIMD111065_RS06180	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
RIMD111065_RS06185	COG0583	DNA-binding transcription factor activity
RIMD111065_RS06195	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RIMD111065_RS06205	COG0583	DNA-binding transcription factor activity
RIMD111065_RS06210	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS06215	COG0616	signal peptide processing
RIMD111065_RS06220	COG3724	N-succinylarginine dihydrolase activity
RIMD111065_RS06240	COG0840	transmembrane signaling receptor activity
RIMD111065_RS06250	COG2971	BadF BadG BcrA BcrD
RIMD111065_RS06260	COG4608	Belongs to the ABC transporter superfamily
RIMD111065_RS06265	COG0444	Belongs to the ABC transporter superfamily
RIMD111065_RS06270	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RIMD111065_RS06275	COG0601	transmembrane transport
RIMD111065_RS06280	COG4166	transmembrane transport
RIMD111065_RS06285	COG2205	protein histidine kinase activity
RIMD111065_RS06285	COG0784	Response regulator, receiver
RIMD111065_RS06320	COG3220	belongs to the UPF0276 family
RIMD111065_RS06350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RIMD111065_RS06355	COG1289	transmembrane transporter activity
RIMD111065_RS06360	COG0303	'Molybdopterin
RIMD111065_RS06365	COG0746	molybdenum cofactor guanylyltransferase activity
RIMD111065_RS06375	COG4662	Binding-protein-dependent transport system inner membrane component
RIMD111065_RS06385	COG2204	response regulator
RIMD111065_RS06390	COG3852	Histidine kinase
RIMD111065_RS06395	COG1910	domain protein
RIMD111065_RS06400	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RIMD111065_RS06440	COG3383	formate dehydrogenase (NAD+) activity
RIMD111065_RS06440	COG3383	formate dehydrogenase (NAD+) activity
RIMD111065_RS06445	COG0437	4 iron, 4 sulfur cluster binding
RIMD111065_RS06460	COG0281	malic enzyme
RIMD111065_RS06480	COG2706	6-phosphogluconolactonase activity
RIMD111065_RS06490	COG1196	nuclear chromosome segregation
RIMD111065_RS06490	COG3264	Mechanosensitive ion channel
RIMD111065_RS06495	COG0469	pyruvate kinase activity
RIMD111065_RS06510	COG4651	solute:proton antiporter activity
RIMD111065_RS06510	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RIMD111065_RS06520	COG2974	May be involved in recombination
RIMD111065_RS06530	COG0420	3'-5' exonuclease activity
RIMD111065_RS06535	COG0419	ATPase involved in DNA repair
RIMD111065_RS06545	COG3038	cytochrome b561
RIMD111065_RS06560	COG2190	(PTS) system
RIMD111065_RS06570	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS06575	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
RIMD111065_RS06580	COG0542	response to heat
RIMD111065_RS06595	COG1720	tRNA m6t6A37 methyltransferase activity
RIMD111065_RS06615	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
RIMD111065_RS06620	COG4988	ABC transporter
RIMD111065_RS06635	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS06645	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
RIMD111065_RS06660	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
RIMD111065_RS06665	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
RIMD111065_RS06675	COG0083	homoserine kinase activity
RIMD111065_RS06680	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RIMD111065_RS06705	COG0813	purine-nucleoside phosphorylase activity
RIMD111065_RS06720	COG2205	protein histidine kinase activity
RIMD111065_RS06720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS06725	COG3384	dioxygenase
RIMD111065_RS06735	COG1283	sodium-dependent phosphate transmembrane transporter activity
RIMD111065_RS06745	COG0531	amino acid
RIMD111065_RS06755	COG0531	amino acid
RIMD111065_RS06770	COG1396	sequence-specific DNA binding
RIMD111065_RS06770	COG1917	Cupin 2, conserved barrel domain protein
RIMD111065_RS06775	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RIMD111065_RS06790	COG3152	Membrane
RIMD111065_RS06815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RIMD111065_RS06820	COG2375	cellular response to nickel ion
RIMD111065_RS06830	COG1136	(ABC) transporter
RIMD111065_RS06830	COG0577	efflux transmembrane transporter activity
RIMD111065_RS06835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RIMD111065_RS06845	COG1227	inorganic diphosphatase activity
RIMD111065_RS06850	COG0497	DNA recombination
RIMD111065_RS06855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
RIMD111065_RS06860	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
RIMD111065_RS06865	COG0443	Heat shock 70 kDa protein
RIMD111065_RS06870	COG0484	heat shock protein binding
RIMD111065_RS06900	COG1285	pathogenesis
RIMD111065_RS06915	COG0640	Transcriptional regulator
RIMD111065_RS06945	COG0095	Lipoate-protein ligase
RIMD111065_RS06965	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RIMD111065_RS06970	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RIMD111065_RS06990	COG0708	Exodeoxyribonuclease III
RIMD111065_RS07005	COG2211	Major facilitator Superfamily
RIMD111065_RS07050	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
RIMD111065_RS07055	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
RIMD111065_RS07060	COG1845	cytochrome c oxidase, subunit III
RIMD111065_RS07065	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
RIMD111065_RS07070	COG0109	protoheme IX farnesyltransferase activity
RIMD111065_RS07075	COG2814	Major facilitator Superfamily
RIMD111065_RS07085	COG2205	protein histidine kinase activity
RIMD111065_RS07085	COG0784	Response regulator, receiver
RIMD111065_RS07085	COG2198	Histidine kinase
RIMD111065_RS07090	COG1879	ABC-type sugar transport system periplasmic component
RIMD111065_RS07100	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS07105	COG3005	denitrification pathway
RIMD111065_RS07115	COG3381	protein complex oligomerization
RIMD111065_RS07155	COG2003	Belongs to the UPF0758 family
RIMD111065_RS07190	COG0583	DNA-binding transcription factor activity
RIMD111065_RS07205	COG0549	Belongs to the carbamate kinase family
RIMD111065_RS07210	COG1304	FMN binding
RIMD111065_RS07215	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RIMD111065_RS07220	COG1335	isochorismatase
RIMD111065_RS07235	COG3311	Transcriptional regulator
RIMD111065_RS07260	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RIMD111065_RS07335	COG0159	tryptophan synthase activity
RIMD111065_RS07340	COG0133	tryptophan synthase activity
RIMD111065_RS07345	COG0134	indole-3-glycerol-phosphate synthase activity
RIMD111065_RS07345	COG0135	phosphoribosylanthranilate isomerase activity
RIMD111065_RS07350	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RIMD111065_RS07355	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
RIMD111065_RS07355	COG0512	Glutamine amidotransferase of anthranilate synthase
RIMD111065_RS07360	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
RIMD111065_RS07370	COG0009	L-threonylcarbamoyladenylate synthase
RIMD111065_RS07380	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
RIMD111065_RS07390	COG1946	Acyl-CoA thioesterase
RIMD111065_RS07405	COG1309	transcriptional regulator
RIMD111065_RS07410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RIMD111065_RS07415	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RIMD111065_RS07430	COG1091	dTDP-4-dehydrorhamnose reductase activity
RIMD111065_RS07460	COG3754	Rhamnan synthesis protein F
RIMD111065_RS07465	COG1215	transferase activity, transferring glycosyl groups
RIMD111065_RS07480	COG2895	sulfate adenylyltransferase (ATP) activity
RIMD111065_RS07485	COG0471	metal ion transport
RIMD111065_RS07485	COG3273	potassium ion transport
RIMD111065_RS07490	COG0529	Catalyzes the synthesis of activated sulfate
RIMD111065_RS07505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
RIMD111065_RS07525	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
RIMD111065_RS07555	COG1086	Polysaccharide biosynthesis protein
RIMD111065_RS07580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
RIMD111065_RS07585	COG0489	protein tyrosine kinase activity
RIMD111065_RS07585	COG3206	protein involved in exopolysaccharide biosynthesis
RIMD111065_RS07605	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RIMD111065_RS07615	COG3132	Protein of unknown function, DUF480
RIMD111065_RS07655	COG1278	Cold shock
RIMD111065_RS07685	COG0697	spore germination
RIMD111065_RS07690	COG1349	DNA-binding transcription factor activity
RIMD111065_RS07695	COG1882	Formate acetyltransferase
RIMD111065_RS07700	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RIMD111065_RS07705	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
RIMD111065_RS07735	COG0622	Phosphoesterase
RIMD111065_RS07750	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
RIMD111065_RS07755	COG0835	chemotaxis
RIMD111065_RS07755	COG0784	Response regulator, receiver
RIMD111065_RS07760	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
RIMD111065_RS07765	COG1815	bacterial-type flagellum-dependent cell motility
RIMD111065_RS07785	COG4787	bacterial-type flagellum-dependent cell motility
RIMD111065_RS07795	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
RIMD111065_RS07800	COG1706	bacterial-type flagellum-dependent cell motility
RIMD111065_RS07805	COG1705	Flagellar rod assembly protein muramidase FlgJ
RIMD111065_RS07805	COG3951	Flagellar rod assembly protein muramidase FlgJ
RIMD111065_RS07810	COG1256	bacterial-type flagellum assembly
RIMD111065_RS07820	COG2239	Acts as a magnesium transporter
RIMD111065_RS07830	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
RIMD111065_RS07835	COG2716	regulation of RNA biosynthetic process
RIMD111065_RS07860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
RIMD111065_RS07865	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
RIMD111065_RS07870	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
RIMD111065_RS07875	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
RIMD111065_RS07895	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
RIMD111065_RS07910	COG0590	tRNA wobble adenosine to inosine editing
RIMD111065_RS07915	COG0573	inorganic phosphate transmembrane transporter activity
RIMD111065_RS07920	COG0581	inorganic phosphate transmembrane transporter activity
RIMD111065_RS07925	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
RIMD111065_RS07930	COG0704	Plays a role in the regulation of phosphate uptake
RIMD111065_RS07935	COG1253	flavin adenine dinucleotide binding
RIMD111065_RS07950	COG0531	amino acid
RIMD111065_RS07970	COG1126	abc transporter atp-binding protein
RIMD111065_RS07975	COG0765	amino acid transport
RIMD111065_RS07980	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS07990	COG2271	Major facilitator Superfamily
RIMD111065_RS08005	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RIMD111065_RS08030	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
RIMD111065_RS08035	COG0477	Major facilitator Superfamily
RIMD111065_RS08040	COG0123	including yeast histone deacetylase and acetoin utilization protein
RIMD111065_RS08050	COG1199	ATP-dependent helicase activity
RIMD111065_RS08065	COG1448	Aminotransferase
RIMD111065_RS08070	COG0433	COG0433 Predicted ATPase
RIMD111065_RS08085	COG0658	competence protein
RIMD111065_RS08085	COG2333	competence protein COMEC
RIMD111065_RS08095	COG1663	tetraacyldisaccharide 4'-kinase activity
RIMD111065_RS08100	COG2835	tetraacyldisaccharide 4'-kinase activity
RIMD111065_RS08105	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
RIMD111065_RS08110	COG2197	response regulator
RIMD111065_RS08115	COG0322	excinuclease ABC activity
RIMD111065_RS08170	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
RIMD111065_RS08175	COG0437	4 iron, 4 sulfur cluster binding
RIMD111065_RS08180	COG3301	Polysulphide reductase, NrfD
RIMD111065_RS08185	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RIMD111065_RS08195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RIMD111065_RS08220	COG2199	diguanylate cyclase activity
RIMD111065_RS08220	COG2203	Gaf domain
RIMD111065_RS08250	COG2119	membrane
RIMD111065_RS08255	COG0023	Translation Initiation Factor
RIMD111065_RS08280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RIMD111065_RS08295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS08295	COG2205	protein histidine kinase activity
RIMD111065_RS08305	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
RIMD111065_RS08315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RIMD111065_RS08320	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
RIMD111065_RS08325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RIMD111065_RS08330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
RIMD111065_RS08335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
RIMD111065_RS08345	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
RIMD111065_RS08350	COG0505	Belongs to the CarA family
RIMD111065_RS08355	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
RIMD111065_RS08360	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RIMD111065_RS08400	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RIMD111065_RS08405	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS08415	COG4104	PAAR repeat-containing protein
RIMD111065_RS08430	COG0789	Transcriptional regulator
RIMD111065_RS08445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS08450	COG0765	amino acid transport
RIMD111065_RS08455	COG1126	abc transporter atp-binding protein
RIMD111065_RS08460	COG0493	'glutamate synthase
RIMD111065_RS08465	COG0070	glutamate synthase
RIMD111065_RS08465	COG0069	glutamate synthase activity
RIMD111065_RS08465	COG0067	glutamate synthase
RIMD111065_RS08470	COG1242	4 iron, 4 sulfur cluster binding
RIMD111065_RS08530	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
RIMD111065_RS08535	COG0574	Belongs to the PEP-utilizing enzyme family
RIMD111065_RS08535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
RIMD111065_RS08565	COG1464	Belongs to the NlpA lipoprotein family
RIMD111065_RS08570	COG0671	phosphoesterase, PA-phosphatase related
RIMD111065_RS08575	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
RIMD111065_RS08580	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RIMD111065_RS08590	COG0101	tRNA pseudouridine synthase activity
RIMD111065_RS08595	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
RIMD111065_RS08600	COG0285	dihydrofolate synthase activity
RIMD111065_RS08605	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
RIMD111065_RS08610	COG2920	part of a sulfur-relay system
RIMD111065_RS08615	COG1289	transmembrane transporter activity
RIMD111065_RS08620	COG0670	Belongs to the BI1 family
RIMD111065_RS08640	COG2194	sulfuric ester hydrolase activity
RIMD111065_RS08645	COG0392	lysyltransferase activity
RIMD111065_RS08645	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
RIMD111065_RS08655	COG0840	transmembrane signaling receptor activity
RIMD111065_RS08660	COG5001	Diguanylate cyclase
RIMD111065_RS08665	COG0564	pseudouridine synthase activity
RIMD111065_RS08680	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
RIMD111065_RS08690	COG0625	glutathione transferase activity
RIMD111065_RS08695	COG0625	glutathione transferase activity
RIMD111065_RS08705	COG0367	asparagine synthase
RIMD111065_RS08715	COG4651	solute:proton antiporter activity
RIMD111065_RS08715	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
RIMD111065_RS08720	COG0647	UMP catabolic process
RIMD111065_RS08725	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RIMD111065_RS08730	COG1902	pentaerythritol trinitrate reductase activity
RIMD111065_RS08735	COG1253	flavin adenine dinucleotide binding
RIMD111065_RS08745	COG0277	FAD linked oxidase domain protein
RIMD111065_RS08745	COG0247	lactate metabolic process
RIMD111065_RS08755	COG2050	protein possibly involved in aromatic compounds catabolism
RIMD111065_RS08765	COG2056	Na+-H+ antiporter family
RIMD111065_RS08770	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
RIMD111065_RS08785	COG0346	lactoylglutathione lyase activity
RIMD111065_RS08790	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
RIMD111065_RS08795	COG4660	Part of a membrane complex involved in electron transport
RIMD111065_RS08800	COG4659	FMN binding
RIMD111065_RS08805	COG4658	electron transport chain
RIMD111065_RS08815	COG2878	Part of a membrane complex involved in electron transport
RIMD111065_RS08820	COG4657	Part of a membrane complex involved in electron transport
RIMD111065_RS08825	COG0697	spore germination
RIMD111065_RS08840	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
RIMD111065_RS08845	COG1288	antiporter activity
RIMD111065_RS08850	COG0436	Aminotransferase
RIMD111065_RS08860	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
RIMD111065_RS08865	COG2027	D-alanyl-D-alanine carboxypeptidase
RIMD111065_RS08870	COG1061	Type III restriction enzyme res subunit
RIMD111065_RS08875	COG1566	PFAM secretion protein HlyD family protein
RIMD111065_RS08885	COG1966	Carbon starvation protein
RIMD111065_RS08890	COG3279	Response regulator of the LytR AlgR family
RIMD111065_RS08895	COG3275	phosphorelay sensor kinase activity
RIMD111065_RS08900	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RIMD111065_RS08900	COG2199	diguanylate cyclase activity
RIMD111065_RS08905	COG1454	alcohol dehydrogenase
RIMD111065_RS08905	COG1012	belongs to the aldehyde dehydrogenase family
RIMD111065_RS08915	COG2095	MarC family integral membrane protein
RIMD111065_RS08925	COG0601	transmembrane transport
RIMD111065_RS08930	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RIMD111065_RS08945	COG0861	Integral membrane protein TerC family
RIMD111065_RS08950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RIMD111065_RS08960	COG1301	dicarboxylic acid transport
RIMD111065_RS08975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
RIMD111065_RS08990	COG0537	adenosine 5'-monophosphoramidase activity
RIMD111065_RS09025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RIMD111065_RS09030	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RIMD111065_RS09040	COG2354	Protein conserved in bacteria
RIMD111065_RS09045	COG1164	Oligoendopeptidase f
RIMD111065_RS09055	COG2233	PERMEase
RIMD111065_RS09060	COG3150	esterase
RIMD111065_RS09065	COG1252	NADH dehydrogenase
RIMD111065_RS09085	COG0393	Putative heavy-metal-binding
RIMD111065_RS09095	COG1648	precorrin-2 dehydrogenase activity
RIMD111065_RS09095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
RIMD111065_RS09115	COG4667	esterase of the alpha-beta hydrolase superfamily
RIMD111065_RS09120	COG1619	proteins homologs of microcin C7 resistance protein MccF
RIMD111065_RS09125	COG1368	sulfuric ester hydrolase activity
RIMD111065_RS09135	COG0527	aspartate kinase activity
RIMD111065_RS09140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
RIMD111065_RS09140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RIMD111065_RS09145	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RIMD111065_RS09165	COG0596	Alpha beta hydrolase
RIMD111065_RS09170	COG0346	lactoylglutathione lyase activity
RIMD111065_RS09180	COG0583	DNA-binding transcription factor activity
RIMD111065_RS09185	COG1620	l-lactate permease
RIMD111065_RS09190	COG0247	lactate metabolic process
RIMD111065_RS09195	COG1139	Iron-sulfur cluster binding protein
RIMD111065_RS09230	COG0577	efflux transmembrane transporter activity
RIMD111065_RS09235	COG1136	(ABC) transporter
RIMD111065_RS09245	COG2814	Major facilitator Superfamily
RIMD111065_RS09265	COG0672	)-iron permease
RIMD111065_RS09295	COG0659	secondary active sulfate transmembrane transporter activity
RIMD111065_RS09315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RIMD111065_RS09320	COG0840	transmembrane signaling receptor activity
RIMD111065_RS09330	COG2201	protein-glutamate methylesterase activity
RIMD111065_RS09345	COG0840	transmembrane signaling receptor activity
RIMD111065_RS09350	COG0643	Histidine kinase
RIMD111065_RS09350	COG2198	Histidine kinase
RIMD111065_RS09360	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS09365	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
RIMD111065_RS09370	COG0437	4 iron, 4 sulfur cluster binding
RIMD111065_RS09375	COG5557	Pfam Polysulphide reductase, NrfD
RIMD111065_RS09380	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
RIMD111065_RS09385	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RIMD111065_RS09390	COG1773	rubredoxin
RIMD111065_RS09400	COG0601	transmembrane transport
RIMD111065_RS09405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RIMD111065_RS09410	COG0444	Belongs to the ABC transporter superfamily
RIMD111065_RS09415	COG3842	ATPase activity
RIMD111065_RS09420	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
RIMD111065_RS09425	COG0375	protein maturation
RIMD111065_RS09430	COG0309	Hydrogenase expression formation protein (HypE)
RIMD111065_RS09440	COG0298	carbon dioxide binding
RIMD111065_RS09445	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
RIMD111065_RS09455	COG1921	L-seryl-tRNASec selenium transferase activity
RIMD111065_RS09465	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
RIMD111065_RS09475	COG3260	NADH ubiquinone oxidoreductase 20
RIMD111065_RS09480	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RIMD111065_RS09485	COG3261	NADH dehydrogenase
RIMD111065_RS09485	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
RIMD111065_RS09490	COG0650	Formate hydrogenlyase subunit 4
RIMD111065_RS09495	COG0651	ATP synthesis coupled electron transport
RIMD111065_RS09500	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RIMD111065_RS09505	COG3158	transport of potassium into the cell
RIMD111065_RS09515	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
RIMD111065_RS09540	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
RIMD111065_RS09545	COG0326	Molecular chaperone. Has ATPase activity
RIMD111065_RS09550	COG0563	adenylate kinase activity
RIMD111065_RS09555	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
RIMD111065_RS09565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RIMD111065_RS09580	COG3300	MHYT domain
RIMD111065_RS09580	COG5001	Diguanylate cyclase
RIMD111065_RS09585	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
RIMD111065_RS09605	COG1021	2,3-dihydroxybenzoate-AMP ligase
RIMD111065_RS09610	COG1535	isochorismatase
RIMD111065_RS09610	COG3433	isochorismatase activity
RIMD111065_RS09615	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RIMD111065_RS09620	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS09630	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
RIMD111065_RS09635	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
RIMD111065_RS09645	COG1120	ATPase activity
RIMD111065_RS09650	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RIMD111065_RS09655	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RIMD111065_RS09660	COG4771	TonB-dependent receptor
RIMD111065_RS09700	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
RIMD111065_RS09705	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
RIMD111065_RS09710	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RIMD111065_RS09725	COG1570	exodeoxyribonuclease VII activity
RIMD111065_RS09730	COG0697	spore germination
RIMD111065_RS09750	COG3119	arylsulfatase activity
RIMD111065_RS09755	COG0641	radical SAM
RIMD111065_RS09765	COG3158	transport of potassium into the cell
RIMD111065_RS09775	COG0517	IMP dehydrogenase activity
RIMD111065_RS09775	COG0516	GMP reductase activity
RIMD111065_RS09780	COG0519	Catalyzes the synthesis of GMP from XMP
RIMD111065_RS09780	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RIMD111065_RS09825	COG2062	phosphohistidine phosphatase, SixA
RIMD111065_RS09835	COG0697	spore germination
RIMD111065_RS09840	COG4166	transmembrane transport
RIMD111065_RS09845	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
RIMD111065_RS09850	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
RIMD111065_RS09860	COG4591	ABC-type transport system involved in lipoprotein release permease component
RIMD111065_RS09865	COG1136	(ABC) transporter
RIMD111065_RS09870	COG4591	ABC-type transport system involved in lipoprotein release permease component
RIMD111065_RS09875	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
RIMD111065_RS09885	COG0544	peptidyl-prolyl cis-trans isomerase activity
RIMD111065_RS09890	COG0740	serine-type endopeptidase activity
RIMD111065_RS09895	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
RIMD111065_RS09900	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
RIMD111065_RS09905	COG0776	regulation of translation
RIMD111065_RS09910	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RIMD111065_RS09915	COG0488	(ABC) transporter
RIMD111065_RS09920	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RIMD111065_RS09925	COG3162	membrane
RIMD111065_RS09970	COG1115	amino acid carrier protein
RIMD111065_RS09985	COG1584	GPR1 FUN34 yaaH family protein
RIMD111065_RS10020	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
RIMD111065_RS10025	COG1960	acyl-CoA dehydrogenase activity
RIMD111065_RS10035	COG1960	acyl-CoA dehydrogenase activity
RIMD111065_RS10040	COG1024	Enoyl-CoA hydratase
RIMD111065_RS10045	COG1024	Enoyl-CoA hydratase
RIMD111065_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS10065	COG0730	response to heat
RIMD111065_RS10150	COG5001	Diguanylate cyclase
RIMD111065_RS10150	COG3300	MHYT domain
RIMD111065_RS10155	COG0583	DNA-binding transcription factor activity
RIMD111065_RS10160	COG2723	6-phospho-beta-galactosidase activity
RIMD111065_RS10165	COG3300	MHYT domain
RIMD111065_RS10165	COG5001	Diguanylate cyclase
RIMD111065_RS10175	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RIMD111065_RS10185	COG0583	DNA-binding transcription factor activity
RIMD111065_RS10190	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
RIMD111065_RS10200	COG0583	DNA-binding transcription factor activity
RIMD111065_RS10210	COG1560	Kdo2-lipid A biosynthetic process
RIMD111065_RS10215	COG1560	Kdo2-lipid A biosynthetic process
RIMD111065_RS10240	COG0417	DNA replication proofreading
RIMD111065_RS10270	COG0534	Mate efflux family protein
RIMD111065_RS10280	COG0307	riboflavin synthase, alpha
RIMD111065_RS10290	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RIMD111065_RS10295	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
RIMD111065_RS10300	COG0697	spore germination
RIMD111065_RS10305	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
RIMD111065_RS10345	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
RIMD111065_RS10350	COG3099	Belongs to the UPF0263 family
RIMD111065_RS10355	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
RIMD111065_RS10360	COG2894	cell division
RIMD111065_RS10365	COG0850	regulation of cytokinetic process
RIMD111065_RS10370	COG3100	YcgL domain-containing protein
RIMD111065_RS10375	COG2951	lytic endotransglycosylase activity
RIMD111065_RS10380	COG1760	l-serine dehydratase
RIMD111065_RS10385	COG1760	l-serine dehydratase
RIMD111065_RS10390	COG3123	guanosine phosphorylase activity
RIMD111065_RS10410	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
RIMD111065_RS10415	COG2067	long-chain fatty acid transport protein
RIMD111065_RS10435	COG1595	DNA-templated transcription, initiation
RIMD111065_RS10465	COG0714	Associated with various cellular activities
RIMD111065_RS10470	COG0183	Belongs to the thiolase family
RIMD111065_RS10475	COG1024	Enoyl-CoA hydratase
RIMD111065_RS10475	COG1250	3-hydroxyacyl-CoA dehydrogenase
RIMD111065_RS10510	COG3829	transcription factor binding
RIMD111065_RS10515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
RIMD111065_RS10520	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
RIMD111065_RS10525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RIMD111065_RS10535	COG0549	Belongs to the carbamate kinase family
RIMD111065_RS10540	COG0697	spore germination
RIMD111065_RS10545	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
RIMD111065_RS10545	COG3608	succinylglutamate desuccinylase aspartoacylase
RIMD111065_RS10550	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
RIMD111065_RS10555	COG2068	MobA-Related Protein
RIMD111065_RS10560	COG0493	'glutamate synthase
RIMD111065_RS10560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RIMD111065_RS10565	COG0402	S-adenosylhomocysteine deaminase activity
RIMD111065_RS10570	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RIMD111065_RS10575	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RIMD111065_RS10575	COG2080	2 iron, 2 sulfur cluster binding
RIMD111065_RS10580	COG2233	PERMEase
RIMD111065_RS10585	COG0402	S-adenosylhomocysteine deaminase activity
RIMD111065_RS10590	COG2252	PERMEase
RIMD111065_RS10595	COG1529	Aldehyde oxidase and xanthine dehydrogenase
RIMD111065_RS10600	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
RIMD111065_RS10605	COG2080	2 iron, 2 sulfur cluster binding
RIMD111065_RS10615	COG3134	Outer membrane lipoprotein
RIMD111065_RS10625	COG1288	antiporter activity
RIMD111065_RS10630	COG0318	PFAM AMP-dependent synthetase and ligase
RIMD111065_RS10635	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
RIMD111065_RS10635	COG0140	phosphoribosyl-ATP diphosphatase activity
RIMD111065_RS10640	COG0107	imidazoleglycerol-phosphate synthase activity
RIMD111065_RS10645	COG0784	Response regulator, receiver
RIMD111065_RS10645	COG2198	Histidine kinase
RIMD111065_RS10645	COG2205	protein histidine kinase activity
RIMD111065_RS10650	COG2199	diguanylate cyclase activity
RIMD111065_RS10655	COG3437	response regulator, receiver
RIMD111065_RS10660	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
RIMD111065_RS10665	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
RIMD111065_RS10670	COG0131	Imidazoleglycerol-phosphate dehydratase
RIMD111065_RS10670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
RIMD111065_RS10675	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
RIMD111065_RS10680	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
RIMD111065_RS10685	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
RIMD111065_RS10695	COG1199	ATP-dependent helicase activity
RIMD111065_RS10700	COG1214	PFAM Peptidase M22, glycoprotease
RIMD111065_RS10710	COG2226	methyltransferase
RIMD111065_RS10710	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
RIMD111065_RS10710	COG0596	Alpha beta hydrolase
RIMD111065_RS10715	COG0318	PFAM AMP-dependent synthetase and ligase
RIMD111065_RS10720	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
RIMD111065_RS10735	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
RIMD111065_RS10740	COG2832	Protein of unknown function (DUF454)
RIMD111065_RS10745	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
RIMD111065_RS10755	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
RIMD111065_RS10760	COG0582	viral genome integration into host DNA
RIMD111065_RS10795	COG5377	YqaJ viral recombinase family
RIMD111065_RS11080	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
RIMD111065_RS11080	COG0617	tRNA 3'-terminal CCA addition
RIMD111065_RS11080	COG0517	IMP dehydrogenase activity
RIMD111065_RS11085	COG1643	Atp-dependent helicase
RIMD111065_RS11095	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
RIMD111065_RS11105	COG3437	response regulator, receiver
RIMD111065_RS11110	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RIMD111065_RS11115	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
RIMD111065_RS11120	COG0709	Synthesizes selenophosphate from selenide and ATP
RIMD111065_RS11135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RIMD111065_RS11140	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RIMD111065_RS11145	COG0840	transmembrane signaling receptor activity
RIMD111065_RS11150	COG1254	Belongs to the acylphosphatase family
RIMD111065_RS11155	COG0625	glutathione transferase activity
RIMD111065_RS11160	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RIMD111065_RS11160	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RIMD111065_RS11165	COG0489	protein tyrosine kinase activity
RIMD111065_RS11170	COG0572	uridine kinase
RIMD111065_RS11175	COG0717	Belongs to the dCTP deaminase family
RIMD111065_RS11180	COG0306	phosphate transporter
RIMD111065_RS11185	COG1530	ribonuclease E activity
RIMD111065_RS11190	COG0564	pseudouridine synthase activity
RIMD111065_RS11195	COG0546	phosphoglycolate phosphatase activity
RIMD111065_RS11200	COG0424	maF-like protein
RIMD111065_RS11205	COG2814	Major facilitator Superfamily
RIMD111065_RS11220	COG1399	metal-binding, possibly nucleic acid-binding protein
RIMD111065_RS11225	COG0333	Belongs to the bacterial ribosomal protein bL32 family
RIMD111065_RS11230	COG0416	fatty acid biosynthetic process
RIMD111065_RS11235	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RIMD111065_RS11245	COG1028	Short-chain dehydrogenase reductase Sdr
RIMD111065_RS11250	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
RIMD111065_RS11260	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
RIMD111065_RS11265	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
RIMD111065_RS11270	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
RIMD111065_RS11275	COG0470	DNA polymerase III
RIMD111065_RS11280	COG0084	hydrolase, TatD family'
RIMD111065_RS11295	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
RIMD111065_RS11295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RIMD111065_RS11300	COG3008	intermembrane lipid transfer
RIMD111065_RS11305	COG2995	paraquat-inducible protein a
RIMD111065_RS11315	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
RIMD111065_RS11320	COG0372	Belongs to the citrate synthase family
RIMD111065_RS11365	COG4221	oxidoreductase activity
RIMD111065_RS11375	COG3141	response to X-ray
RIMD111065_RS11385	COG1067	ATP-dependent peptidase activity
RIMD111065_RS11390	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RIMD111065_RS11405	COG0488	(ABC) transporter
RIMD111065_RS11415	COG0116	Belongs to the methyltransferase superfamily
RIMD111065_RS11415	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
RIMD111065_RS11425	COG0167	dihydroorotate dehydrogenase activity
RIMD111065_RS11430	COG2902	Dehydrogenase
RIMD111065_RS11440	COG0308	aminopeptidase N
RIMD111065_RS11450	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
RIMD111065_RS11455	COG1956	GAF domain-containing protein
RIMD111065_RS11465	COG3278	Belongs to the heme-copper respiratory oxidase family
RIMD111065_RS11480	COG2010	Cytochrome c
RIMD111065_RS11505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RIMD111065_RS11510	COG0589	response to stress
RIMD111065_RS11515	COG0037	tRNA processing
RIMD111065_RS11530	COG0625	glutathione transferase activity
RIMD111065_RS11535	COG1869	D-ribose catabolic process
RIMD111065_RS11540	COG1129	ABC transporter
RIMD111065_RS11545	COG1172	Belongs to the binding-protein-dependent transport system permease family
RIMD111065_RS11550	COG1879	ABC-type sugar transport system periplasmic component
RIMD111065_RS11555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RIMD111065_RS11560	COG1609	Transcriptional regulator
RIMD111065_RS11565	COG5001	Diguanylate cyclase
RIMD111065_RS11565	COG3300	MHYT domain
RIMD111065_RS11595	COG0776	regulation of translation
RIMD111065_RS11600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RIMD111065_RS11600	COG0072	phenylalanine-tRNA ligase activity
RIMD111065_RS11605	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
RIMD111065_RS11610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
RIMD111065_RS11615	COG0291	Belongs to the bacterial ribosomal protein bL35 family
RIMD111065_RS11620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
RIMD111065_RS11625	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
RIMD111065_RS11650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RIMD111065_RS11660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RIMD111065_RS11665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RIMD111065_RS11670	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RIMD111065_RS11675	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
RIMD111065_RS11680	COG3313	Fe-S protein
RIMD111065_RS11685	COG2942	2-epimerase
RIMD111065_RS11690	COG3716	PTS system mannose fructose sorbose family IID component
RIMD111065_RS11695	COG3715	PTS system
RIMD111065_RS11700	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS11700	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS11715	COG1609	Transcriptional regulator
RIMD111065_RS11720	COG2140	Oxalate decarboxylase
RIMD111065_RS11725	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RIMD111065_RS11725	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
RIMD111065_RS11725	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RIMD111065_RS11730	COG1105	Belongs to the carbohydrate kinase PfkB family
RIMD111065_RS11735	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS11735	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS11740	COG1609	Transcriptional regulator
RIMD111065_RS11745	COG0814	amino acid
RIMD111065_RS11755	COG5654	RES domain protein
RIMD111065_RS11760	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS11770	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
RIMD111065_RS11775	COG2890	protein-(glutamine-N5) methyltransferase activity
RIMD111065_RS11780	COG2840	Smr protein MutS2
RIMD111065_RS11790	COG3706	GGDEF domain
RIMD111065_RS11795	COG0406	alpha-ribazole phosphatase activity
RIMD111065_RS11820	COG2824	Alkylphosphonate utilization operon protein PhnA
RIMD111065_RS11830	COG0384	phenazine biosynthesis protein PhzF
RIMD111065_RS11860	COG0242	peptide deformylase activity
RIMD111065_RS11880	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
RIMD111065_RS11885	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
RIMD111065_RS11895	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
RIMD111065_RS11900	COG1434	Gram-negative-bacterium-type cell wall biogenesis
RIMD111065_RS11910	COG0205	6-phosphofructokinase activity
RIMD111065_RS11915	COG1473	amidohydrolase
RIMD111065_RS11920	COG1011	Hydrolase
RIMD111065_RS11925	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RIMD111065_RS11985	COG3593	DNA synthesis involved in DNA repair
RIMD111065_RS12000	COG0583	DNA-binding transcription factor activity
RIMD111065_RS12005	COG0730	response to heat
RIMD111065_RS12010	COG3148	PFAM DTW domain containing protein
RIMD111065_RS12020	COG1181	Belongs to the D-alanine--D-alanine ligase family
RIMD111065_RS12030	COG0386	Belongs to the glutathione peroxidase family
RIMD111065_RS12035	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS12040	COG0456	acetyltransferase
RIMD111065_RS12050	COG1742	UPF0060 membrane protein
RIMD111065_RS12080	COG2329	Antibiotic biosynthesis monooxygenase
RIMD111065_RS12085	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RIMD111065_RS12105	COG3243	poly(R)-hydroxyalkanoic acid synthase
RIMD111065_RS12115	COG2501	S4 domain
RIMD111065_RS12130	COG1132	(ABC) transporter
RIMD111065_RS12135	COG1132	(ABC) transporter
RIMD111065_RS12145	COG3118	belongs to the thioredoxin family
RIMD111065_RS12150	COG0471	metal ion transport
RIMD111065_RS12155	COG0058	SHG alpha-glucan phosphorylase activity
RIMD111065_RS12185	COG0814	amino acid
RIMD111065_RS12190	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
RIMD111065_RS12195	COG0514	ATP-dependent DNA helicase (RecQ)
RIMD111065_RS12200	COG2766	serine protein kinase
RIMD111065_RS12210	COG2719	SpoVR family
RIMD111065_RS12215	COG2186	Transcriptional regulator
RIMD111065_RS12220	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RIMD111065_RS12225	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
RIMD111065_RS12230	COG0586	Pfam SNARE associated Golgi protein
RIMD111065_RS12240	COG0556	nucleotide-excision repair
RIMD111065_RS12250	COG2985	domain, Protein
RIMD111065_RS12250	COG0569	domain protein
RIMD111065_RS12255	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
RIMD111065_RS12275	COG4565	transcriptional regulatory protein
RIMD111065_RS12280	COG3290	protein histidine kinase activity
RIMD111065_RS12285	COG1846	Transcriptional regulator
RIMD111065_RS12285	COG1940	carbohydrate kinase activity
RIMD111065_RS12290	COG0840	transmembrane signaling receptor activity
RIMD111065_RS12295	COG3012	SEC-C Motif Domain Protein
RIMD111065_RS12300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
RIMD111065_RS12305	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
RIMD111065_RS12310	COG0247	lactate metabolic process
RIMD111065_RS12330	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
RIMD111065_RS12335	COG0437	4 iron, 4 sulfur cluster binding
RIMD111065_RS12340	COG3301	Polysulphide reductase, NrfD
RIMD111065_RS12345	COG1138	Cytochrome C-type biogenesis protein
RIMD111065_RS12355	COG3088	subunit of a heme lyase
RIMD111065_RS12355	COG4235	cytochrome complex assembly
RIMD111065_RS12360	COG1051	belongs to the nudix hydrolase family
RIMD111065_RS12370	COG3033	Beta-eliminating lyase
RIMD111065_RS12380	COG3046	protein related to deoxyribodipyrimidine photolyase
RIMD111065_RS12385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RIMD111065_RS12405	COG0516	GMP reductase activity
RIMD111065_RS12405	COG0517	IMP dehydrogenase activity
RIMD111065_RS12415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
RIMD111065_RS12430	COG4774	siderophore transport
RIMD111065_RS12445	COG0583	DNA-binding transcription factor activity
RIMD111065_RS12450	COG2910	NAD(P)H-binding
RIMD111065_RS12465	COG0612	Peptidase, M16
RIMD111065_RS12470	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
RIMD111065_RS12480	COG1944	ATP diphosphatase activity
RIMD111065_RS12485	COG2116	formate transmembrane transporter activity
RIMD111065_RS12490	COG1882	Formate acetyltransferase
RIMD111065_RS12495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
RIMD111065_RS12500	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
RIMD111065_RS12505	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
RIMD111065_RS12515	COG1840	ABC-type Fe3 transport system, periplasmic component
RIMD111065_RS12520	COG3842	ATPase activity
RIMD111065_RS12535	COG2983	Belongs to the UPF0260 family
RIMD111065_RS12545	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
RIMD111065_RS12550	COG0045	succinate-CoA ligase (ADP-forming) activity
RIMD111065_RS12555	COG0508	dehydrogenase complex catalyzes the overall conversion of
RIMD111065_RS12560	COG0567	Dehydrogenase, E1 component
RIMD111065_RS12570	COG1053	succinate dehydrogenase
RIMD111065_RS12575	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
RIMD111065_RS12600	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
RIMD111065_RS12605	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RIMD111065_RS12605	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
RIMD111065_RS12615	COG3069	C4-dicarboxylate transmembrane transporter activity
RIMD111065_RS12630	COG1451	nucleotide metabolic process
RIMD111065_RS12645	COG0254	rRNA binding
RIMD111065_RS12650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RIMD111065_RS12660	COG0583	DNA-binding transcription factor activity
RIMD111065_RS12670	COG1172	Belongs to the binding-protein-dependent transport system permease family
RIMD111065_RS12680	COG1879	ABC-type sugar transport system periplasmic component
RIMD111065_RS12685	COG1069	ribulokinase activity
RIMD111065_RS12695	COG2160	L-arabinose isomerase activity
RIMD111065_RS12725	COG2916	Histone family protein nucleoid-structuring protein H-NS
RIMD111065_RS12760	COG0438	transferase activity, transferring glycosyl groups
RIMD111065_RS12825	COG0438	transferase activity, transferring glycosyl groups
RIMD111065_RS12830	COG1215	transferase activity, transferring glycosyl groups
RIMD111065_RS12835	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
RIMD111065_RS12875	COG2205	protein histidine kinase activity
RIMD111065_RS12875	COG0784	Response regulator, receiver
RIMD111065_RS12895	COG0753	catalase activity
RIMD111065_RS12920	COG0784	Response regulator, receiver
RIMD111065_RS12920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RIMD111065_RS12945	COG2925	Exonuclease
RIMD111065_RS12955	COG3345	alpha-galactosidase
RIMD111065_RS12960	COG1380	Effector of murein hydrolase LrgA
RIMD111065_RS12965	COG1346	cytolysis
RIMD111065_RS12970	COG0295	cytidine deaminase activity
RIMD111065_RS12975	COG1022	Amp-dependent synthetase and ligase
RIMD111065_RS12990	COG0861	Integral membrane protein TerC family
RIMD111065_RS12995	COG2885	chlorophyll binding
RIMD111065_RS13000	COG2199	diguanylate cyclase activity
RIMD111065_RS13020	COG2154	pterin-4-alpha-carbinolamine dehydratase
RIMD111065_RS13030	COG3768	UPF0283 membrane protein
RIMD111065_RS13035	COG3106	COG3106 Predicted ATPase
RIMD111065_RS13050	COG1842	Phage shock protein A
RIMD111065_RS13055	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
RIMD111065_RS13065	COG4168	peptide transport system, permease
RIMD111065_RS13070	COG4171	peptide transport system, permease
RIMD111065_RS13080	COG4172	Belongs to the ABC transporter superfamily
RIMD111065_RS13090	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
RIMD111065_RS13095	COG1286	toxin biosynthetic process
RIMD111065_RS13100	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
RIMD111065_RS13105	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
RIMD111065_RS13110	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
RIMD111065_RS13115	COG0531	amino acid
RIMD111065_RS13115	COG1674	ftsk spoiiie
RIMD111065_RS13125	COG0686	Belongs to the AlaDH PNT family
RIMD111065_RS13130	COG0492	ferredoxin-NADP+ reductase activity
RIMD111065_RS13135	COG3706	GGDEF domain
RIMD111065_RS13140	COG3134	Outer membrane lipoprotein
RIMD111065_RS13145	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
RIMD111065_RS13150	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
RIMD111065_RS13155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
RIMD111065_RS13160	COG0542	response to heat
RIMD111065_RS13165	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
RIMD111065_RS13170	COG1278	Cold shock
RIMD111065_RS13175	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
RIMD111065_RS13240	COG3829	transcription factor binding
RIMD111065_RS13315	COG3501	Rhs element vgr protein
RIMD111065_RS13340	COG1435	thymidine kinase activity
RIMD111065_RS13345	COG1757	Na H antiporter
RIMD111065_RS13350	COG2916	Histone family protein nucleoid-structuring protein H-NS
RIMD111065_RS13355	COG2096	Adenosyltransferase
RIMD111065_RS13360	COG3530	Putative quorum-sensing-regulated virulence factor
RIMD111065_RS13365	COG0602	queuosine metabolic process
RIMD111065_RS13370	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
RIMD111065_RS13390	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
RIMD111065_RS13400	COG0776	regulation of translation
RIMD111065_RS13405	COG0539	negative regulation of cytoplasmic translation
RIMD111065_RS13410	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
RIMD111065_RS13415	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RIMD111065_RS13425	COG0583	DNA-binding transcription factor activity
RIMD111065_RS13445	COG0778	Nitroreductase
RIMD111065_RS13450	COG5001	Diguanylate cyclase
RIMD111065_RS13450	COG3300	MHYT domain
RIMD111065_RS13460	COG0583	DNA-binding transcription factor activity
RIMD111065_RS13465	COG3437	response regulator, receiver
RIMD111065_RS13490	COG4989	oxidoreductase activity
RIMD111065_RS13495	COG0724	RNA recognition motif
RIMD111065_RS13515	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
RIMD111065_RS13530	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RIMD111065_RS13535	COG1360	Flagellar Motor Protein
RIMD111065_RS13540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RIMD111065_RS13545	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RIMD111065_RS13550	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RIMD111065_RS13550	COG0649	NAD binding
RIMD111065_RS13565	COG1034	ATP synthesis coupled electron transport
RIMD111065_RS13570	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
RIMD111065_RS13575	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RIMD111065_RS13580	COG0839	Belongs to the complex I subunit 6 family
RIMD111065_RS13585	COG0713	ATP synthesis coupled electron transport
RIMD111065_RS13595	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
RIMD111065_RS13600	COG1007	ATP synthesis coupled electron transport
RIMD111065_RS13615	COG2199	diguanylate cyclase activity
RIMD111065_RS13615	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RIMD111065_RS13620	COG0047	phosphoribosylformylglycinamidine synthase activity
RIMD111065_RS13620	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
RIMD111065_RS13625	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
RIMD111065_RS13630	COG1645	bacterial-type flagellum-dependent swarming motility
RIMD111065_RS13635	COG1160	GTP binding
RIMD111065_RS13640	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RIMD111065_RS13645	COG2976	Protein conserved in bacteria
RIMD111065_RS13650	COG0124	histidyl-tRNA synthetase
RIMD111065_RS13655	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
RIMD111065_RS13670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
RIMD111065_RS13675	COG0105	UTP biosynthetic process
RIMD111065_RS13680	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
RIMD111065_RS13690	COG0633	Ferredoxin
RIMD111065_RS13695	COG0443	Heat shock 70 kDa protein
RIMD111065_RS13700	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RIMD111065_RS13710	COG0822	iron-sulfur transferase activity
RIMD111065_RS13715	COG1104	cysteine desulfurase activity
RIMD111065_RS13735	COG3154	lipid carrier protein
RIMD111065_RS13740	COG0826	peptidase U32
RIMD111065_RS13745	COG0826	peptidase U32
RIMD111065_RS13760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RIMD111065_RS13765	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
RIMD111065_RS13770	COG1862	Preprotein translocase
RIMD111065_RS13775	COG0343	queuine tRNA-ribosyltransferase activity
RIMD111065_RS13780	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
RIMD111065_RS13785	COG0517	IMP dehydrogenase activity
RIMD111065_RS13795	COG3634	alkyl hydroperoxide reductase activity
RIMD111065_RS13815	COG1393	Belongs to the ArsC family
RIMD111065_RS13820	COG0798	PFAM Bile acid sodium symporter
RIMD111065_RS13825	COG0640	Transcriptional regulator
RIMD111065_RS13840	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RIMD111065_RS13840	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
RIMD111065_RS13845	COG0509	glycine decarboxylation via glycine cleavage system
RIMD111065_RS13850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
RIMD111065_RS13855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RIMD111065_RS13860	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
RIMD111065_RS13880	COG2814	Major facilitator Superfamily
RIMD111065_RS13885	COG0625	glutathione transferase activity
RIMD111065_RS13895	COG0483	inositol monophosphate 1-phosphatase activity
RIMD111065_RS13915	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RIMD111065_RS13930	COG1086	Polysaccharide biosynthesis protein
RIMD111065_RS13950	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
RIMD111065_RS13960	COG2089	acid synthase
RIMD111065_RS14015	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
RIMD111065_RS14030	COG0301	tRNA thio-modification
RIMD111065_RS14030	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RIMD111065_RS14040	COG4953	penicillin-binding protein 1C
RIMD111065_RS14045	COG2373	Large extracellular alpha-helical protein
RIMD111065_RS14050	COG0446	pyridine nucleotide-disulphide oxidoreductase
RIMD111065_RS14060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RIMD111065_RS14080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS14090	COG2431	L-lysine efflux transmembrane transporter activity
RIMD111065_RS14095	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RIMD111065_RS14100	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
RIMD111065_RS14115	COG1393	Belongs to the ArsC family
RIMD111065_RS14125	COG4783	chaperone-mediated protein folding
RIMD111065_RS14130	COG0425	Belongs to the sulfur carrier protein TusA family
RIMD111065_RS14150	COG3842	ATPase activity
RIMD111065_RS14155	COG3833	ABC-type maltose transport systems, permease component
RIMD111065_RS14160	COG1175	transmembrane transport
RIMD111065_RS14170	COG3081	Nucleoid-associated protein
RIMD111065_RS14175	COG3082	Protein of unknown function (DUF1414)
RIMD111065_RS14180	COG3083	sulfuric ester hydrolase activity
RIMD111065_RS14185	COG4771	TonB-dependent receptor
RIMD111065_RS14190	COG1770	oligopeptidase
RIMD111065_RS14210	COG4574	serine-type endopeptidase inhibitor activity
RIMD111065_RS14215	COG3085	chromosome segregation
RIMD111065_RS14220	COG0583	DNA-binding transcription factor activity
RIMD111065_RS14225	COG1605	Chorismate mutase
RIMD111065_RS14225	COG0287	Prephenate dehydrogenase
RIMD111065_RS14230	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
RIMD111065_RS14235	COG0584	glycerophosphoryl diester phosphodiesterase
RIMD111065_RS14250	COG1349	DNA-binding transcription factor activity
RIMD111065_RS14255	COG2271	Major facilitator Superfamily
RIMD111065_RS14260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RIMD111065_RS14265	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
RIMD111065_RS14270	COG0583	DNA-binding transcription factor activity
RIMD111065_RS14300	COG0656	L-ascorbic acid biosynthetic process
RIMD111065_RS14305	COG2814	Major facilitator Superfamily
RIMD111065_RS14315	COG1294	oxidase, subunit
RIMD111065_RS14320	COG1271	oxidase subunit
RIMD111065_RS14325	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
RIMD111065_RS14330	COG2979	Protein of unknown function (DUF533)
RIMD111065_RS14360	COG2271	Major facilitator Superfamily
RIMD111065_RS14365	COG0583	DNA-binding transcription factor activity
RIMD111065_RS14375	COG2807	transmembrane transport
RIMD111065_RS14380	COG1187	pseudouridine synthase activity
RIMD111065_RS14395	COG0346	lactoylglutathione lyase activity
RIMD111065_RS14405	COG1403	HNH endonuclease
RIMD111065_RS14420	COG3681	Belongs to the UPF0597 family
RIMD111065_RS14430	COG0814	amino acid
RIMD111065_RS14450	COG1166	arginine decarboxylase activity
RIMD111065_RS14460	COG2195	Cleaves the N-terminal amino acid of tripeptides
RIMD111065_RS14490	COG0583	DNA-binding transcription factor activity
RIMD111065_RS14500	COG2759	Belongs to the formate--tetrahydrofolate ligase family
RIMD111065_RS14505	COG0840	transmembrane signaling receptor activity
RIMD111065_RS14510	COG0302	gtp cyclohydrolase
RIMD111065_RS14520	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RIMD111065_RS14525	COG2267	carboxylic ester hydrolase activity
RIMD111065_RS14530	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
RIMD111065_RS14545	COG0314	molybdopterin synthase activity
RIMD111065_RS14550	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
RIMD111065_RS14555	COG0315	cyclic pyranopterin monophosphate synthase activity
RIMD111065_RS14560	COG0521	Mo-molybdopterin cofactor biosynthetic process
RIMD111065_RS14565	COG3005	denitrification pathway
RIMD111065_RS14575	COG0348	domain, Protein
RIMD111065_RS14580	COG0437	4 iron, 4 sulfur cluster binding
RIMD111065_RS14585	COG0243	molybdopterin cofactor binding
RIMD111065_RS14595	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
RIMD111065_RS14595	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RIMD111065_RS14600	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
RIMD111065_RS14605	COG3850	Histidine kinase
RIMD111065_RS14610	COG2197	response regulator
RIMD111065_RS14640	COG0121	glutamine amidotransferase
RIMD111065_RS14645	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
RIMD111065_RS14650	COG1960	acyl-CoA dehydrogenase activity
RIMD111065_RS14655	COG3437	response regulator, receiver
RIMD111065_RS14655	COG0784	Response regulator, receiver
RIMD111065_RS14670	COG0328	RNA-DNA hybrid ribonuclease activity
RIMD111065_RS14675	COG2226	methyltransferase
RIMD111065_RS14680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
RIMD111065_RS14685	COG0741	lytic transglycosylase activity
RIMD111065_RS14685	COG1388	LysM domain
RIMD111065_RS14690	COG3021	interspecies interaction between organisms
RIMD111065_RS14700	COG1607	acyl-coa hydrolase
RIMD111065_RS14715	COG0741	lytic transglycosylase activity
RIMD111065_RS14725	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
RIMD111065_RS14745	COG2911	Protein conserved in bacteria
RIMD111065_RS14750	COG0729	surface antigen
RIMD111065_RS14760	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
RIMD111065_RS14765	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
RIMD111065_RS14775	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
RIMD111065_RS14785	COG4134	Bacterial extracellular solute-binding protein
RIMD111065_RS14795	COG4136	ATPase activity
RIMD111065_RS14800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
RIMD111065_RS14805	COG2951	lytic endotransglycosylase activity
RIMD111065_RS14820	COG1846	Transcriptional regulator
RIMD111065_RS14830	COG0033	Phosphoglucomutase
RIMD111065_RS14835	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
RIMD111065_RS14840	COG0596	Alpha beta hydrolase
RIMD111065_RS14855	COG0716	FMN binding
RIMD111065_RS14865	COG0735	belongs to the Fur family
RIMD111065_RS14870	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
RIMD111065_RS14880	COG2190	(PTS) system
RIMD111065_RS14880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS14880	COG1263	PTS System
RIMD111065_RS14885	COG0363	glucosamine-6-phosphate deaminase activity
RIMD111065_RS14890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
RIMD111065_RS14895	COG1846	Transcriptional regulator
RIMD111065_RS14895	COG1940	carbohydrate kinase activity
RIMD111065_RS14900	COG2194	sulfuric ester hydrolase activity
RIMD111065_RS14905	COG0217	transcriptional regulatory protein
RIMD111065_RS14910	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
RIMD111065_RS14915	COG1801	Protein of unknown function DUF72
RIMD111065_RS14920	COG4106	trans-aconitate 2-methyltransferase activity
RIMD111065_RS14925	COG0500	methyltransferase
RIMD111065_RS14945	COG0450	alkyl hydroperoxide reductase
RIMD111065_RS14950	COG0583	DNA-binding transcription factor activity
RIMD111065_RS14960	COG0791	NLP P60 protein
RIMD111065_RS14975	COG1309	transcriptional regulator
RIMD111065_RS15015	COG0534	Mate efflux family protein
RIMD111065_RS15040	COG0674	pyruvate-flavodoxin oxidoreductase activity
RIMD111065_RS15040	COG1013	pyruvate-flavodoxin oxidoreductase activity
RIMD111065_RS15040	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
RIMD111065_RS15040	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
RIMD111065_RS15050	COG3217	Mosc domain protein beta barrel domain protein
RIMD111065_RS15050	COG0633	Ferredoxin
RIMD111065_RS15050	COG3217	Mosc domain protein beta barrel domain protein
RIMD111065_RS15050	COG0633	Ferredoxin
RIMD111065_RS15060	COG0501	Belongs to the peptidase M48B family
RIMD111065_RS15065	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
RIMD111065_RS15070	COG2226	methyltransferase
RIMD111065_RS15070	COG1073	alpha beta
RIMD111065_RS15075	COG0156	8-amino-7-oxononanoate synthase activity
RIMD111065_RS15080	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RIMD111065_RS15100	COG0017	Asparaginyl-tRNA synthetase
RIMD111065_RS15105	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RIMD111065_RS15120	COG3069	C4-dicarboxylate transmembrane transporter activity
RIMD111065_RS15130	COG0583	DNA-binding transcription factor activity
RIMD111065_RS15135	COG1393	Belongs to the ArsC family
RIMD111065_RS15140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
RIMD111065_RS15145	COG1876	peptidase activity
RIMD111065_RS15155	COG3263	regulation of cellular component size
RIMD111065_RS15175	COG1280	lysine exporter protein (LysE YggA)
RIMD111065_RS15205	COG0564	pseudouridine synthase activity
RIMD111065_RS15215	COG1454	alcohol dehydrogenase
RIMD111065_RS15220	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
RIMD111065_RS15225	COG0702	epimerase
RIMD111065_RS15230	COG2914	Belongs to the UPF0125 (RnfH) family
RIMD111065_RS15235	COG2867	negative regulation of translational initiation
RIMD111065_RS15240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
RIMD111065_RS15250	COG0582	viral genome integration into host DNA
RIMD111065_RS15330	COG1715	Restriction endonuclease
RIMD111065_RS15335	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
RIMD111065_RS15350	COG3171	Protein conserved in bacteria
RIMD111065_RS15360	COG0583	DNA-binding transcription factor activity
RIMD111065_RS15365	COG3048	D-serine ammonia-lyase activity
RIMD111065_RS15375	COG0538	isocitrate dehydrogenase activity
RIMD111065_RS15380	COG2207	Transcriptional regulator
RIMD111065_RS15400	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RIMD111065_RS15415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
RIMD111065_RS15420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS15420	COG1263	PTS System
RIMD111065_RS15425	COG1609	Transcriptional regulator
RIMD111065_RS15430	COG0446	pyridine nucleotide-disulphide oxidoreductase
RIMD111065_RS15430	COG1902	pentaerythritol trinitrate reductase activity
RIMD111065_RS15435	COG0789	Transcriptional regulator
RIMD111065_RS15445	COG0456	acetyltransferase
RIMD111065_RS15465	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS15465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RIMD111065_RS15465	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RIMD111065_RS15475	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RIMD111065_RS15475	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
RIMD111065_RS15475	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS15485	COG1187	pseudouridine synthase activity
RIMD111065_RS15495	COG0482	sulfurtransferase activity
RIMD111065_RS15500	COG2915	High frequency lysogenization protein hflD homolog
RIMD111065_RS15505	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
RIMD111065_RS15510	COG2850	peptidyl-arginine hydroxylation
RIMD111065_RS15515	COG3153	acetyltransferase
RIMD111065_RS15525	COG0625	glutathione transferase activity
RIMD111065_RS15530	COG0259	pyridoxamine-phosphate oxidase activity
RIMD111065_RS15545	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RIMD111065_RS15545	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RIMD111065_RS15550	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
RIMD111065_RS15565	COG3088	subunit of a heme lyase
RIMD111065_RS15565	COG4235	cytochrome complex assembly
RIMD111065_RS15570	COG4235	cytochrome complex assembly
RIMD111065_RS15570	COG3088	subunit of a heme lyase
RIMD111065_RS15575	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
RIMD111065_RS15580	COG1138	Cytochrome C-type biogenesis protein
RIMD111065_RS15585	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
RIMD111065_RS15590	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RIMD111065_RS15595	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RIMD111065_RS15600	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
RIMD111065_RS15615	COG0835	chemotaxis
RIMD111065_RS15625	COG1192	Involved in chromosome partitioning
RIMD111065_RS15630	COG1360	Flagellar Motor Protein
RIMD111065_RS15635	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
RIMD111065_RS15640	COG2201	protein-glutamate methylesterase activity
RIMD111065_RS15645	COG0784	Response regulator, receiver
RIMD111065_RS15645	COG2198	Histidine kinase
RIMD111065_RS15645	COG0643	Histidine kinase
RIMD111065_RS15650	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
RIMD111065_RS15675	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
RIMD111065_RS15685	COG1684	flagellar biosynthetic protein fliR
RIMD111065_RS15740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
RIMD111065_RS15750	COG1677	Flagellar hook-basal body complex protein FliE
RIMD111065_RS15765	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
RIMD111065_RS15775	COG3064	Membrane
RIMD111065_RS15775	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
RIMD111065_RS15775	COG1073	alpha beta
RIMD111065_RS15780	COG2994	toxin metabolic process
RIMD111065_RS15790	COG2274	protein secretion by the type I secretion system
RIMD111065_RS15800	COG2274	protein secretion by the type I secretion system
RIMD111065_RS15820	COG1737	Transcriptional regulator
RIMD111065_RS15825	COG0469	pyruvate kinase activity
RIMD111065_RS15840	COG1960	acyl-CoA dehydrogenase activity
RIMD111065_RS15850	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
RIMD111065_RS15860	COG0243	molybdopterin cofactor binding
RIMD111065_RS15865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
RIMD111065_RS15870	COG0583	DNA-binding transcription factor activity
RIMD111065_RS15905	COG1454	alcohol dehydrogenase
RIMD111065_RS15905	COG1012	belongs to the aldehyde dehydrogenase family
RIMD111065_RS15920	COG1882	Formate acetyltransferase
RIMD111065_RS15925	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RIMD111065_RS15935	COG4869	propanediol catabolic process
RIMD111065_RS15975	COG4409	exo-alpha-(2->6)-sialidase activity
RIMD111065_RS15980	COG2731	YhcH YjgK YiaL family protein
RIMD111065_RS15985	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
RIMD111065_RS15995	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
RIMD111065_RS16000	COG1737	Transcriptional regulator
RIMD111065_RS16005	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
RIMD111065_RS16010	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
RIMD111065_RS16015	COG1349	DNA-binding transcription factor activity
RIMD111065_RS16020	COG0738	Major facilitator superfamily
RIMD111065_RS16030	COG1070	Carbohydrate kinase
RIMD111065_RS16050	COG4172	Belongs to the ABC transporter superfamily
RIMD111065_RS16055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
RIMD111065_RS16065	COG0747	negative chemotaxis
RIMD111065_RS16080	COG1376	ErfK ybiS ycfS ynhG family protein
RIMD111065_RS16080	COG1388	LysM domain
RIMD111065_RS16095	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
RIMD111065_RS16100	COG0791	NLP P60 protein
RIMD111065_RS16105	COG2091	lysine biosynthetic process via aminoadipic acid
RIMD111065_RS16110	COG3118	belongs to the thioredoxin family
RIMD111065_RS16120	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
RIMD111065_RS16125	COG0788	formyltetrahydrofolate deformylase activity
RIMD111065_RS16135	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RIMD111065_RS16155	COG0366	Alpha amylase catalytic
RIMD111065_RS16160	COG0741	lytic transglycosylase activity
RIMD111065_RS16160	COG0739	heme binding
RIMD111065_RS16160	COG1196	nuclear chromosome segregation
RIMD111065_RS16165	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
RIMD111065_RS16170	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
RIMD111065_RS16180	COG0673	inositol 2-dehydrogenase activity
RIMD111065_RS16220	COG1032	radical SAM domain protein
RIMD111065_RS16230	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
RIMD111065_RS16235	COG1566	PFAM secretion protein HlyD family protein
RIMD111065_RS16245	COG1752	Esterase of the alpha-beta hydrolase superfamily
RIMD111065_RS16250	COG0733	neurotransmitter:sodium symporter activity
RIMD111065_RS16280	COG0281	malic enzyme
RIMD111065_RS16290	COG0534	Mate efflux family protein
RIMD111065_RS16305	COG2233	PERMEase
RIMD111065_RS16310	COG0095	Lipoate-protein ligase
RIMD111065_RS16315	COG1115	amino acid carrier protein
RIMD111065_RS16320	COG0019	diaminopimelate decarboxylase activity
RIMD111065_RS16330	COG0678	peroxiredoxin activity
RIMD111065_RS16340	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
RIMD111065_RS16360	COG1131	(ABC) transporter
RIMD111065_RS16365	COG0545	Peptidyl-prolyl cis-trans isomerase
RIMD111065_RS16375	COG3142	Participates in the control of copper homeostasis
RIMD111065_RS16400	COG5002	protein histidine kinase activity
RIMD111065_RS16405	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS16410	COG0346	lactoylglutathione lyase activity
RIMD111065_RS16415	COG1804	L-carnitine dehydratase bile acid-inducible protein F
RIMD111065_RS16420	COG1960	acyl-CoA dehydrogenase activity
RIMD111065_RS16425	COG3284	Transcriptional regulator
RIMD111065_RS16440	COG0697	spore germination
RIMD111065_RS16445	COG4565	transcriptional regulatory protein
RIMD111065_RS16450	COG3290	protein histidine kinase activity
RIMD111065_RS16455	COG0281	malic enzyme
RIMD111065_RS16470	COG1846	Transcriptional regulator
RIMD111065_RS16475	COG1566	PFAM secretion protein HlyD family protein
RIMD111065_RS16505	COG0602	queuosine metabolic process
RIMD111065_RS16510	COG1328	CTP reductase activity
RIMD111065_RS16520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
RIMD111065_RS16525	COG3115	cell septum assembly
RIMD111065_RS16530	COG1196	nuclear chromosome segregation
RIMD111065_RS16540	COG2860	membrane
RIMD111065_RS16550	COG3108	Peptidase M15
RIMD111065_RS16555	COG2989	Protein conserved in bacteria
RIMD111065_RS16570	COG0463	Glycosyl transferase, family 2
RIMD111065_RS16585	COG0366	Alpha amylase catalytic
RIMD111065_RS16625	COG3706	GGDEF domain
RIMD111065_RS16630	COG0037	tRNA processing
RIMD111065_RS16635	COG3590	peptidase
RIMD111065_RS16645	COG0488	(ABC) transporter
RIMD111065_RS16655	COG0531	amino acid
RIMD111065_RS16665	COG1073	alpha beta
RIMD111065_RS16670	COG1073	alpha beta
RIMD111065_RS16685	COG0814	amino acid
RIMD111065_RS16700	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
RIMD111065_RS16705	COG1982	Orn Lys Arg decarboxylase major
RIMD111065_RS16710	COG0531	amino acid
RIMD111065_RS16715	COG3710	Transcriptional regulator
RIMD111065_RS16720	COG0825	malonyl-CoA metabolic process
RIMD111065_RS16730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
RIMD111065_RS16735	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RIMD111065_RS16740	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RIMD111065_RS16745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
RIMD111065_RS16750	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
RIMD111065_RS16765	COG0750	zinc metalloprotease
RIMD111065_RS16770	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
RIMD111065_RS16775	COG0575	Belongs to the CDS family
RIMD111065_RS16780	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
RIMD111065_RS16785	COG0233	cytoplasmic translational termination
RIMD111065_RS16790	COG0528	UMP kinase activity
RIMD111065_RS16795	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
RIMD111065_RS16800	COG0052	Belongs to the universal ribosomal protein uS2 family
RIMD111065_RS16805	COG0024	Methionine aminopeptidase
RIMD111065_RS16810	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
RIMD111065_RS16815	COG2171	N-acyltransferase activity
RIMD111065_RS16825	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS16825	COG1263	PTS System
RIMD111065_RS16835	COG4580	involved in the transport of maltose and maltodextrins
RIMD111065_RS16845	COG0564	pseudouridine synthase activity
RIMD111065_RS16850	COG3098	single-species biofilm formation
RIMD111065_RS16875	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
RIMD111065_RS16885	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RIMD111065_RS16885	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
RIMD111065_RS16900	COG1611	Belongs to the LOG family
RIMD111065_RS16905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RIMD111065_RS16910	COG0473	3-isopropylmalate dehydrogenase activity
RIMD111065_RS16920	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
RIMD111065_RS16925	COG2363	Small membrane protein
RIMD111065_RS16935	COG0583	DNA-binding transcription factor activity
RIMD111065_RS16940	COG0840	transmembrane signaling receptor activity
RIMD111065_RS16945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
RIMD111065_RS16960	COG1477	protein flavinylation
RIMD111065_RS16965	COG2871	sodium ion transport
RIMD111065_RS16970	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
RIMD111065_RS16975	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
RIMD111065_RS16980	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
RIMD111065_RS16985	COG1805	sodium ion transport
RIMD111065_RS16990	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
RIMD111065_RS16995	COG0271	Belongs to the BolA IbaG family
RIMD111065_RS17000	COG2813	Specifically methylates the guanine in position
RIMD111065_RS17010	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
RIMD111065_RS17020	COG2211	Major facilitator Superfamily
RIMD111065_RS17030	COG1666	GTP binding
RIMD111065_RS17035	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
RIMD111065_RS17040	COG0693	protein deglycase activity
RIMD111065_RS17105	COG2771	luxR family
RIMD111065_RS17110	COG0582	viral genome integration into host DNA
RIMD111065_RS17235	COG2200	EAL domain
RIMD111065_RS17265	COG4983	Phage plasmid primase, P4 family domain protein
RIMD111065_RS17285	COG5377	YqaJ viral recombinase family
RIMD111065_RS17330	COG2003	Belongs to the UPF0758 family
RIMD111065_RS17385	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
RIMD111065_RS17385	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RIMD111065_RS17390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
RIMD111065_RS17400	COG1151	hydroxylamine reductase activity
RIMD111065_RS17405	COG0783	Belongs to the Dps family
RIMD111065_RS17430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
RIMD111065_RS17445	COG4221	oxidoreductase activity
RIMD111065_RS17455	COG0415	Belongs to the DNA photolyase family
RIMD111065_RS17460	COG0789	Transcriptional regulator
RIMD111065_RS17465	COG3272	Protein of unknown function (DUF1722)
RIMD111065_RS17495	COG0077	Prephenate dehydratase
RIMD111065_RS17495	COG1605	Chorismate mutase
RIMD111065_RS17520	COG1349	DNA-binding transcription factor activity
RIMD111065_RS17525	COG2084	Dehydrogenase
RIMD111065_RS17535	COG0235	Class ii aldolase
RIMD111065_RS17540	COG3622	Belongs to the hyi family
RIMD111065_RS17545	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RIMD111065_RS17550	COG2610	gluconate transmembrane transporter activity
RIMD111065_RS17560	COG0840	transmembrane signaling receptor activity
RIMD111065_RS17570	COG0300	oxidoreductase activity
RIMD111065_RS17595	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
RIMD111065_RS17610	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
RIMD111065_RS17620	COG0826	peptidase U32
RIMD111065_RS17625	COG1280	lysine exporter protein (LysE YggA)
RIMD111065_RS17635	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
RIMD111065_RS17640	COG0840	transmembrane signaling receptor activity
RIMD111065_RS17655	COG2198	Histidine kinase
RIMD111065_RS17655	COG0643	Histidine kinase
RIMD111065_RS17665	COG0835	chemotaxis
RIMD111065_RS17670	COG0840	transmembrane signaling receptor activity
RIMD111065_RS17680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
RIMD111065_RS17685	COG2201	protein-glutamate methylesterase activity
RIMD111065_RS17690	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
RIMD111065_RS17720	COG2197	response regulator
RIMD111065_RS17745	COG2203	Gaf domain
RIMD111065_RS17745	COG2200	EAL domain
RIMD111065_RS17745	COG2199	diguanylate cyclase activity
RIMD111065_RS17750	COG0826	peptidase U32
RIMD111065_RS17755	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
RIMD111065_RS17760	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
RIMD111065_RS17765	COG0305	Participates in initiation and elongation during chromosome replication
RIMD111065_RS17775	COG2200	EAL domain
RIMD111065_RS17780	COG0737	Belongs to the 5'-nucleotidase family
RIMD111065_RS17800	COG2204	response regulator
RIMD111065_RS17805	COG0545	Peptidyl-prolyl cis-trans isomerase
RIMD111065_RS17820	COG1047	Peptidyl-prolyl cis-trans
RIMD111065_RS17825	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
RIMD111065_RS17835	COG0784	Response regulator, receiver
RIMD111065_RS17835	COG0835	chemotaxis
RIMD111065_RS17840	COG0429	hydrolase of the alpha beta-hydrolase fold
RIMD111065_RS17845	COG5001	Diguanylate cyclase
RIMD111065_RS17845	COG4251	negative regulation of phosphorylation
RIMD111065_RS17845	COG3706	GGDEF domain
RIMD111065_RS17845	COG2203	Gaf domain
RIMD111065_RS17850	COG3089	Belongs to the UPF0270 family
RIMD111065_RS17860	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
RIMD111065_RS17865	COG0463	Glycosyl transferase, family 2
RIMD111065_RS17870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
RIMD111065_RS17870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RIMD111065_RS17875	COG0726	polysaccharide deacetylase
RIMD111065_RS17880	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
RIMD111065_RS17885	COG2076	Multidrug Resistance protein
RIMD111065_RS17890	COG2076	Multidrug Resistance protein
RIMD111065_RS17895	COG3954	Phosphoribulokinase
RIMD111065_RS17910	COG1765	OsmC-like protein
RIMD111065_RS17920	COG2226	methyltransferase
RIMD111065_RS17925	COG3397	chitin binding
RIMD111065_RS17940	COG2205	protein histidine kinase activity
RIMD111065_RS17940	COG2202	Pas domain
RIMD111065_RS17950	COG3655	Transcriptional regulator
RIMD111065_RS17955	COG2814	Major facilitator Superfamily
RIMD111065_RS17960	COG4771	TonB-dependent receptor
RIMD111065_RS17980	COG0748	coenzyme F420 binding
RIMD111065_RS17985	COG3721	Heme iron utilization protein
RIMD111065_RS17995	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
RIMD111065_RS18020	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
RIMD111065_RS18025	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RIMD111065_RS18030	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
RIMD111065_RS18050	COG0741	lytic transglycosylase activity
RIMD111065_RS18055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
RIMD111065_RS18070	COG0488	(ABC) transporter
RIMD111065_RS18080	COG2252	PERMEase
RIMD111065_RS18085	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
RIMD111065_RS18090	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
RIMD111065_RS18095	COG3178	'Phosphotransferase
RIMD111065_RS18100	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
RIMD111065_RS18110	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
RIMD111065_RS18115	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
RIMD111065_RS18120	COG2967	ApaG domain
RIMD111065_RS18125	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
RIMD111065_RS18135	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
RIMD111065_RS18140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
RIMD111065_RS18155	COG0318	PFAM AMP-dependent synthetase and ligase
RIMD111065_RS18160	COG3314	Sporulation integral membrane protein YlbJ
RIMD111065_RS18165	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
RIMD111065_RS18170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
RIMD111065_RS18175	COG0261	This protein binds to 23S rRNA in the presence of protein L20
RIMD111065_RS18180	COG0142	geranyltranstransferase activity
RIMD111065_RS18185	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
RIMD111065_RS18190	COG0330	HflC and HflK could
RIMD111065_RS18195	COG0330	HflC and HflK could
RIMD111065_RS18200	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
RIMD111065_RS18205	COG1923	regulation of RNA biosynthetic process
RIMD111065_RS18210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
RIMD111065_RS18215	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
RIMD111065_RS18225	COG0802	atpase or kinase
RIMD111065_RS18230	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
RIMD111065_RS18230	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
RIMD111065_RS18235	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
RIMD111065_RS18250	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
RIMD111065_RS18255	COG2011	ABC-type metal ion transport system permease component
RIMD111065_RS18260	COG1464	Belongs to the NlpA lipoprotein family
RIMD111065_RS18270	COG0840	transmembrane signaling receptor activity
RIMD111065_RS18295	COG5002	protein histidine kinase activity
RIMD111065_RS18295	COG0784	Response regulator, receiver
RIMD111065_RS18295	COG2198	Histidine kinase
RIMD111065_RS18315	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
RIMD111065_RS18330	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
RIMD111065_RS18335	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
RIMD111065_RS18345	COG2716	regulation of RNA biosynthetic process
RIMD111065_RS18350	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
RIMD111065_RS18355	COG3013	Belongs to the UPF0304 family
RIMD111065_RS18365	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
RIMD111065_RS18370	COG0857	belongs to the CobB CobQ family
RIMD111065_RS18370	COG0280	phosphate acetyltransferase
RIMD111065_RS18380	COG0028	Belongs to the TPP enzyme family
RIMD111065_RS18390	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
RIMD111065_RS18395	COG0671	phosphoesterase, PA-phosphatase related
RIMD111065_RS18405	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
RIMD111065_RS18410	COG0473	3-isopropylmalate dehydrogenase activity
RIMD111065_RS18415	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
RIMD111065_RS18420	COG0066	3-isopropylmalate dehydratase activity
RIMD111065_RS18435	COG4143	(ABC) transporter
RIMD111065_RS18440	COG1178	ABC-type Fe3 transport system permease component
RIMD111065_RS18445	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
RIMD111065_RS18450	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
RIMD111065_RS18460	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
RIMD111065_RS18495	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
RIMD111065_RS18500	COG0564	pseudouridine synthase activity
RIMD111065_RS18510	COG3300	MHYT domain
RIMD111065_RS18510	COG5001	Diguanylate cyclase
RIMD111065_RS18520	COG0459	protein refolding
RIMD111065_RS18525	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
RIMD111065_RS18530	COG0534	Mate efflux family protein
RIMD111065_RS18535	COG3030	protein affecting phage T7 exclusion by the F plasmid
RIMD111065_RS18540	COG1027	Aspartate ammonia-lyase
RIMD111065_RS18545	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
RIMD111065_RS18560	COG0477	Major facilitator Superfamily
RIMD111065_RS18570	COG3227	Zinc metalloprotease (Elastase)
RIMD111065_RS18575	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RIMD111065_RS18580	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RIMD111065_RS18590	COG0673	inositol 2-dehydrogenase activity
RIMD111065_RS18600	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
RIMD111065_RS18605	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RIMD111065_RS18610	COG3036	rescue of stalled ribosome
RIMD111065_RS18625	COG0138	bifunctional purine biosynthesis protein purh
RIMD111065_RS18630	COG0151	Belongs to the GarS family
RIMD111065_RS18655	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
RIMD111065_RS18660	COG0358	DNA primase activity
RIMD111065_RS18665	COG1610	YqeY-like protein
RIMD111065_RS18670	COG0828	Belongs to the bacterial ribosomal protein bS21 family
RIMD111065_RS18675	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
RIMD111065_RS18685	COG4942	peptidase
RIMD111065_RS18685	COG1388	LysM domain
RIMD111065_RS18690	COG1238	metal cluster binding
RIMD111065_RS18695	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
RIMD111065_RS18700	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
RIMD111065_RS18705	COG0585	pseudouridine synthase activity
RIMD111065_RS18715	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
RIMD111065_RS18720	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
RIMD111065_RS18725	COG0148	phosphopyruvate hydratase activity
RIMD111065_RS18730	COG0504	CTP synthase activity
RIMD111065_RS18735	COG3956	TIGRFAM MazG family protein
RIMD111065_RS18740	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
RIMD111065_RS18745	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
RIMD111065_RS18755	COG4807	Protein conserved in bacteria
RIMD111065_RS18760	COG3023	N-Acetylmuramoyl-L-alanine amidase
RIMD111065_RS18770	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
RIMD111065_RS18775	COG1381	Involved in DNA repair and RecF pathway recombination
RIMD111065_RS18785	COG0571	ribonuclease III activity
RIMD111065_RS18790	COG0681	Belongs to the peptidase S26 family
RIMD111065_RS18795	COG0481	GTPase activity
RIMD111065_RS18810	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
RIMD111065_RS18815	COG1595	DNA-templated transcription, initiation
RIMD111065_RS18820	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
RIMD111065_RS18830	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
RIMD111065_RS18860	COG4232	protein-disulfide reductase activity
RIMD111065_RS18870	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
RIMD111065_RS18880	COG0126	phosphoglycerate kinase activity
RIMD111065_RS18885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
RIMD111065_RS18890	COG1940	carbohydrate kinase activity
RIMD111065_RS18895	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
RIMD111065_RS18910	COG4991	sh3 domain protein
RIMD111065_RS18915	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
RIMD111065_RS18930	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
RIMD111065_RS18950	COG1505	serine-type exopeptidase activity
RIMD111065_RS18955	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
RIMD111065_RS18960	COG0765	amino acid transport
RIMD111065_RS18965	COG0765	amino acid transport
RIMD111065_RS18970	COG1126	abc transporter atp-binding protein
RIMD111065_RS18975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS18980	COG1136	(ABC) transporter
RIMD111065_RS18980	COG0577	efflux transmembrane transporter activity
RIMD111065_RS18985	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
RIMD111065_RS18990	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS18995	COG2205	protein histidine kinase activity
RIMD111065_RS19000	COG2816	NAD+ diphosphatase activity
RIMD111065_RS19030	COG2070	2-Nitropropane dioxygenase
RIMD111065_RS19060	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
RIMD111065_RS19085	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS19105	COG0154	amidase activity
RIMD111065_RS19110	COG2957	Belongs to the agmatine deiminase family
RIMD111065_RS19125	COG1902	pentaerythritol trinitrate reductase activity
RIMD111065_RS19160	COG3300	MHYT domain
RIMD111065_RS19160	COG5001	Diguanylate cyclase
RIMD111065_RS19170	COG0714	Associated with various cellular activities
RIMD111065_RS19180	COG0456	acetyltransferase
RIMD111065_RS19190	COG1022	Amp-dependent synthetase and ligase
RIMD111065_RS19200	COG2918	glutathione biosynthetic process
RIMD111065_RS19205	COG0612	Peptidase, M16
RIMD111065_RS19210	COG1238	metal cluster binding
RIMD111065_RS19235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RIMD111065_RS19240	COG0359	binds to the 23S rRNA
RIMD111065_RS19245	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
RIMD111065_RS19250	COG0360	Binds together with S18 to 16S ribosomal RNA
RIMD111065_RS19255	COG1914	H( )-stimulated, divalent metal cation uptake system
RIMD111065_RS19275	COG2153	protein acetylation
RIMD111065_RS19290	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
RIMD111065_RS19295	COG0557	exoribonuclease II activity
RIMD111065_RS19300	COG3706	GGDEF domain
RIMD111065_RS19305	COG1854	S-ribosylhomocysteine lyase activity
RIMD111065_RS19320	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
RIMD111065_RS19320	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RIMD111065_RS19380	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
RIMD111065_RS19385	COG1047	Peptidyl-prolyl cis-trans
RIMD111065_RS19390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
RIMD111065_RS19395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
RIMD111065_RS19400	COG0196	riboflavin kinase activity
RIMD111065_RS19410	COG0728	peptidoglycan biosynthetic process
RIMD111065_RS19415	COG0268	Binds directly to 16S ribosomal RNA
RIMD111065_RS19420	COG0640	Transcriptional regulator
RIMD111065_RS19425	COG0583	DNA-binding transcription factor activity
RIMD111065_RS19435	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
RIMD111065_RS19440	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
RIMD111065_RS19445	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
RIMD111065_RS19455	COG1051	belongs to the nudix hydrolase family
RIMD111065_RS19460	COG3066	DNA modification
RIMD111065_RS19470	COG0335	large ribosomal subunit rRNA binding
RIMD111065_RS19475	COG0336	Belongs to the RNA methyltransferase TrmD family
RIMD111065_RS19480	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
RIMD111065_RS19485	COG0228	four-way junction DNA binding
RIMD111065_RS19490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
RIMD111065_RS19495	COG4137	Cytochrome C assembly protein
RIMD111065_RS19500	COG4536	flavin adenine dinucleotide binding
RIMD111065_RS19510	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
RIMD111065_RS19510	COG1017	nitric oxide dioxygenase activity
RIMD111065_RS19515	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
RIMD111065_RS19520	COG0039	L-malate dehydrogenase activity
RIMD111065_RS19525	COG4160	amino acid transport
RIMD111065_RS19530	COG4215	(ABC) transporter
RIMD111065_RS19535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
RIMD111065_RS19540	COG1126	abc transporter atp-binding protein
RIMD111065_RS19545	COG1438	arginine binding
RIMD111065_RS19550	COG2837	iron assimilation
RIMD111065_RS19555	COG3842	ATPase activity
RIMD111065_RS19565	COG1840	ABC-type Fe3 transport system, periplasmic component
RIMD111065_RS19570	COG0347	Belongs to the P(II) protein family
RIMD111065_RS19585	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RIMD111065_RS19590	COG0583	DNA-binding transcription factor activity
RIMD111065_RS19605	COG1929	Belongs to the glycerate kinase type-1 family
RIMD111065_RS19610	COG2610	gluconate transmembrane transporter activity
RIMD111065_RS19615	COG3835	regulator
RIMD111065_RS19620	COG3112	Uncharacterised protein family (UPF0231)
RIMD111065_RS19635	COG0840	transmembrane signaling receptor activity
RIMD111065_RS19655	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS19695	COG1448	Aminotransferase
RIMD111065_RS19710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
RIMD111065_RS19715	COG1328	CTP reductase activity
RIMD111065_RS19735	COG4946	Tricorn protease homolog
RIMD111065_RS19735	COG0793	Belongs to the peptidase S41A family
RIMD111065_RS19765	COG0840	transmembrane signaling receptor activity
RIMD111065_RS19770	COG3397	chitin binding
RIMD111065_RS19775	COG0583	DNA-binding transcription factor activity
RIMD111065_RS19780	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
RIMD111065_RS19785	COG4208	sulfate ABC transporter
RIMD111065_RS19790	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
RIMD111065_RS19800	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
RIMD111065_RS19805	COG3174	membrane
RIMD111065_RS19810	COG0110	maltose O-acetyltransferase activity
RIMD111065_RS19835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
RIMD111065_RS19845	COG0165	Argininosuccinate lyase
RIMD111065_RS19850	COG0137	argininosuccinate synthase activity
RIMD111065_RS19860	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
RIMD111065_RS19865	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
RIMD111065_RS19875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
RIMD111065_RS19885	COG0527	aspartate kinase activity
RIMD111065_RS19885	COG0460	homoserine dehydrogenase
RIMD111065_RS19890	COG0626	cystathionine gamma-synthase activity
RIMD111065_RS19905	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RIMD111065_RS19910	COG0814	amino acid
RIMD111065_RS19915	COG1218	3'(2'),5'-bisphosphate nucleotidase
RIMD111065_RS19920	COG0494	nUDIX hydrolase
RIMD111065_RS19925	COG1011	Hydrolase
RIMD111065_RS19930	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
RIMD111065_RS19945	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
RIMD111065_RS19955	COG3156	type II secretion system protein K
RIMD111065_RS19965	COG4795	General secretion pathway protein
RIMD111065_RS19970	COG2165	general secretion pathway protein
RIMD111065_RS19985	COG2165	general secretion pathway protein
RIMD111065_RS19990	COG1459	type II secretion system
RIMD111065_RS19995	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RIMD111065_RS20005	COG3031	protein transport across the cell outer membrane
RIMD111065_RS20015	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
RIMD111065_RS20020	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
RIMD111065_RS20040	COG0456	acetyltransferase
RIMD111065_RS20045	COG3133	Outer membrane lipoprotein
RIMD111065_RS20060	COG2771	luxR family
RIMD111065_RS20065	COG3916	Acyl-homoserine-lactone synthase
RIMD111065_RS20075	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
RIMD111065_RS20080	COG1309	transcriptional regulator
RIMD111065_RS20090	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
RIMD111065_RS20090	COG2213	PTS system mannitol-specific
RIMD111065_RS20095	COG0246	Mannitol dehydrogenase
RIMD111065_RS20100	COG3722	fumarate hydratase activity
RIMD111065_RS20105	COG3263	regulation of cellular component size
RIMD111065_RS20130	COG1671	Belongs to the UPF0178 family
RIMD111065_RS20145	COG1988	membrane-bound metal-dependent
RIMD111065_RS20150	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
RIMD111065_RS20155	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS20180	COG1575	Belongs to the MenA family. Type 1 subfamily
RIMD111065_RS20185	COG1169	isochorismate synthase
RIMD111065_RS20190	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
RIMD111065_RS20195	COG0596	Alpha beta hydrolase
RIMD111065_RS20200	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
RIMD111065_RS20205	COG1441	menaquinone biosynthetic process
RIMD111065_RS20210	COG0318	PFAM AMP-dependent synthetase and ligase
RIMD111065_RS20225	COG3539	Fimbrial protein
RIMD111065_RS20230	COG3121	Chaperone
RIMD111065_RS20235	COG3188	usher protein
RIMD111065_RS20245	COG3539	Fimbrial protein
RIMD111065_RS20255	COG3291	Pkd domain containing protein
RIMD111065_RS20260	COG2949	membrane
RIMD111065_RS20265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
RIMD111065_RS20275	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
RIMD111065_RS20280	COG5380	lipid catabolic process
RIMD111065_RS20295	COG4533	DNA binding
RIMD111065_RS20305	COG2873	o-acetylhomoserine
RIMD111065_RS20315	COG1979	alcohol dehydrogenase
RIMD111065_RS20335	COG4221	oxidoreductase activity
RIMD111065_RS20355	COG1285	pathogenesis
RIMD111065_RS20375	COG1368	sulfuric ester hydrolase activity
RIMD111065_RS20380	COG1522	sequence-specific DNA binding
RIMD111065_RS20390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
RIMD111065_RS20395	COG1418	mRNA catabolic process
RIMD111065_RS20400	COG1546	Belongs to the CinA family
RIMD111065_RS20400	COG1058	Belongs to the CinA family
RIMD111065_RS20410	COG1129	ABC transporter
RIMD111065_RS20410	COG0842	Transport permease protein
RIMD111065_RS20425	COG0561	phosphatase activity
RIMD111065_RS20430	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
RIMD111065_RS20450	COG1011	Hydrolase
RIMD111065_RS20465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
RIMD111065_RS20470	COG0019	diaminopimelate decarboxylase activity
RIMD111065_RS20480	COG1965	Belongs to the frataxin family
RIMD111065_RS20485	COG0400	carboxylic ester hydrolase activity
RIMD111065_RS20490	COG3072	Adenylate cyclase
RIMD111065_RS20495	COG0181	hydroxymethylbilane synthase activity
RIMD111065_RS20505	COG2959	enzyme of heme biosynthesis
RIMD111065_RS20520	COG1494	fructose-1,6-bisphosphatase
RIMD111065_RS20560	COG1733	regulation of RNA biosynthetic process
RIMD111065_RS20580	COG3932	Exopolysaccharide synthesis, ExoD
RIMD111065_RS20585	COG0814	amino acid
RIMD111065_RS20590	COG3706	GGDEF domain
RIMD111065_RS20605	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
RIMD111065_RS20630	COG1943	Transposase
RIMD111065_RS20635	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
RIMD111065_RS20640	COG2022	thiamine diphosphate biosynthetic process
RIMD111065_RS20650	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
RIMD111065_RS20655	COG0352	thiamine-phosphate diphosphorylase activity
RIMD111065_RS20660	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
RIMD111065_RS20680	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS20685	COG0642	Histidine kinase
RIMD111065_RS20695	COG0189	ligase activity
RIMD111065_RS20720	COG1639	'signal transduction protein
RIMD111065_RS20730	COG2321	neutral zinc metallopeptidase
RIMD111065_RS20735	COG3700	Belongs to the class B bacterial acid phosphatase family
RIMD111065_RS20760	COG2172	sigma factor antagonist activity
RIMD111065_RS20765	COG2205	protein histidine kinase activity
RIMD111065_RS20765	COG5002	protein histidine kinase activity
RIMD111065_RS20765	COG0784	Response regulator, receiver
RIMD111065_RS20770	COG3437	response regulator, receiver
RIMD111065_RS20780	COG0477	Major facilitator Superfamily
RIMD111065_RS20795	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
RIMD111065_RS20800	COG1263	PTS System
RIMD111065_RS20800	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
RIMD111065_RS20820	COG0312	modulator of DNA gyrase
RIMD111065_RS20825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
RIMD111065_RS20835	COG3164	Protein of unknown function
RIMD111065_RS20840	COG1530	ribonuclease E activity
RIMD111065_RS20845	COG0424	maF-like protein
RIMD111065_RS20850	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
RIMD111065_RS20855	COG1792	Involved in formation and maintenance of cell shape
RIMD111065_RS20860	COG1077	Cell shape determining protein MreB Mrl
RIMD111065_RS20885	COG4968	Prepilin-type N-terminal cleavage methylation domain
RIMD111065_RS20895	COG2165	general secretion pathway protein
RIMD111065_RS20905	COG1459	type II secretion system
RIMD111065_RS20910	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
RIMD111065_RS20955	COG2200	EAL domain
RIMD111065_RS20955	COG2199	diguanylate cyclase activity
RIMD111065_RS20960	COG2200	EAL domain
RIMD111065_RS20965	COG0387	Pfam Sodium calcium exchanger
RIMD111065_RS20970	COG2986	histidine ammonia-lyase
RIMD111065_RS20975	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
RIMD111065_RS20980	COG0010	Belongs to the arginase family
RIMD111065_RS20985	COG1228	amidohydrolase
RIMD111065_RS20990	COG2188	Transcriptional regulator
RIMD111065_RS20995	COG0288	reversible hydration of carbon dioxide
RIMD111065_RS21005	COG2177	Part of the ABC transporter FtsEX involved in
RIMD111065_RS21010	COG2884	Cell division ATP-binding protein ftsE
RIMD111065_RS21015	COG0552	protein localization to endoplasmic reticulum
RIMD111065_RS21020	COG0742	ribosomal rna small subunit methyltransferase
RIMD111065_RS21045	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RIMD111065_RS21055	COG0741	lytic transglycosylase activity
RIMD111065_RS21065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RIMD111065_RS21075	COG2095	MarC family integral membrane protein
RIMD111065_RS21085	COG1301	dicarboxylic acid transport
RIMD111065_RS21110	COG3714	YhhN family
RIMD111065_RS21135	COG1770	oligopeptidase
RIMD111065_RS21150	COG4221	oxidoreductase activity
RIMD111065_RS21155	COG0583	DNA-binding transcription factor activity
RIMD111065_RS21160	COG2249	NAD(P)H dehydrogenase (quinone) activity
RIMD111065_RS21205	COG0203	ribosomal protein L17
RIMD111065_RS21210	COG0202	RNA polymerase activity
RIMD111065_RS21215	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
RIMD111065_RS21220	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
RIMD111065_RS21225	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
RIMD111065_RS21230	COG0257	Belongs to the bacterial ribosomal protein bL36 family
RIMD111065_RS21235	COG0201	protein transport
RIMD111065_RS21240	COG0200	Binds to the 23S rRNA
RIMD111065_RS21245	COG1841	ribosomal large subunit assembly
RIMD111065_RS21250	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
RIMD111065_RS21255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
RIMD111065_RS21260	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
RIMD111065_RS21265	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
RIMD111065_RS21270	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
RIMD111065_RS21275	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
RIMD111065_RS21280	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
RIMD111065_RS21285	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
RIMD111065_RS21290	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
RIMD111065_RS21295	COG0255	Belongs to the universal ribosomal protein uL29 family
RIMD111065_RS21300	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
RIMD111065_RS21305	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
RIMD111065_RS21310	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
RIMD111065_RS21315	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
RIMD111065_RS21320	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
RIMD111065_RS21325	COG0089	rRNA binding
RIMD111065_RS21330	COG0088	Forms part of the polypeptide exit tunnel
RIMD111065_RS21335	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
RIMD111065_RS21340	COG0051	transcription antitermination factor activity, RNA binding
RIMD111065_RS21360	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
RIMD111065_RS21365	COG2183	response to ionizing radiation
RIMD111065_RS21385	COG0596	Alpha beta hydrolase
RIMD111065_RS21390	COG1040	competence protein
RIMD111065_RS21395	COG0316	Belongs to the HesB IscA family
RIMD111065_RS21395	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
RIMD111065_RS21400	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
RIMD111065_RS21405	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
RIMD111065_RS21410	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RIMD111065_RS21415	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
RIMD111065_RS21420	COG4942	peptidase
RIMD111065_RS21430	COG1609	Transcriptional regulator
RIMD111065_RS21435	COG0800	Aldolase
RIMD111065_RS21445	COG3265	gluconokinase activity
RIMD111065_RS21450	COG2610	gluconate transmembrane transporter activity
RIMD111065_RS21455	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
RIMD111065_RS21460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
RIMD111065_RS21470	COG0456	acetyltransferase
RIMD111065_RS21480	COG1490	D-aminoacyl-tRNA deacylase activity
RIMD111065_RS21485	COG1295	ribonuclease BN
RIMD111065_RS21490	COG1295	ribonuclease BN
RIMD111065_RS21495	COG1217	gtp-binding protein TYPA
RIMD111065_RS21500	COG0174	glutamine synthetase
RIMD111065_RS21510	COG3852	Histidine kinase
RIMD111065_RS21515	COG2204	response regulator
RIMD111065_RS21520	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
RIMD111065_RS21525	COG0635	Involved in the biosynthesis of porphyrin-containing compound
RIMD111065_RS21535	COG3078	GTPase activator activity
RIMD111065_RS21545	COG0218	Necessary for normal cell division and for the maintenance of normal septation
RIMD111065_RS21555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
RIMD111065_RS21560	COG0408	coproporphyrinogen oxidase activity
RIMD111065_RS21565	COG0009	L-threonylcarbamoyladenylate synthase
RIMD111065_RS21575	COG0551	DNA topoisomerase type I activity
RIMD111065_RS21580	COG2922	Belongs to the Smg family
RIMD111065_RS21585	COG0758	DNA mediated transformation
RIMD111065_RS21595	COG0242	peptide deformylase activity
RIMD111065_RS21600	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
RIMD111065_RS21605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
RIMD111065_RS21605	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
RIMD111065_RS21610	COG0569	domain protein
RIMD111065_RS21615	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RIMD111065_RS21620	COG1322	Protein conserved in bacteria
RIMD111065_RS21640	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
RIMD111065_RS21645	COG0686	Belongs to the AlaDH PNT family
RIMD111065_RS21650	COG0519	Catalyzes the synthesis of GMP from XMP
RIMD111065_RS21650	COG0518	GMP synthase (glutamine-hydrolyzing) activity
RIMD111065_RS21660	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
RIMD111065_RS21665	COG1396	sequence-specific DNA binding
RIMD111065_RS21670	COG1012	belongs to the aldehyde dehydrogenase family
RIMD111065_RS21680	COG2962	Rard protein
RIMD111065_RS21690	COG1280	lysine exporter protein (LysE YggA)
RIMD111065_RS21700	COG0840	transmembrane signaling receptor activity
RIMD111065_RS21705	COG2391	methyltransferase activity
RIMD111065_RS21710	COG1280	lysine exporter protein (LysE YggA)
RIMD111065_RS21765	COG0583	DNA-binding transcription factor activity
RIMD111065_RS21770	COG1943	Transposase
RIMD111065_RS21780	COG0210	DNA helicase
RIMD111065_RS21785	COG1744	ABC transporter substrate-binding protein PnrA-like
RIMD111065_RS21790	COG3845	ABC transporter
RIMD111065_RS21795	COG4603	Belongs to the binding-protein-dependent transport system permease family
RIMD111065_RS21800	COG1079	Belongs to the binding-protein-dependent transport system permease family
RIMD111065_RS21805	COG0583	DNA-binding transcription factor activity
RIMD111065_RS21825	COG1262	PFAM Formylglycine-generating sulfatase enzyme
RIMD111065_RS21830	COG0385	Bile acid
RIMD111065_RS21835	COG0531	amino acid
RIMD111065_RS21840	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
RIMD111065_RS21845	COG0531	amino acid
RIMD111065_RS21850	COG2731	YhcH YjgK YiaL family protein
RIMD111065_RS21855	COG3250	beta-galactosidase activity
RIMD111065_RS21860	COG1609	Transcriptional regulator
RIMD111065_RS21900	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
RIMD111065_RS21905	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RIMD111065_RS21905	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
RIMD111065_RS21910	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
RIMD111065_RS21915	COG3074	FtsZ-dependent cytokinesis
RIMD111065_RS21925	COG1045	serine acetyltransferase
RIMD111065_RS21935	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS21940	COG2205	protein histidine kinase activity
RIMD111065_RS21945	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
RIMD111065_RS21950	COG0534	Mate efflux family protein
RIMD111065_RS21965	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
RIMD111065_RS21970	COG2937	Belongs to the GPAT DAPAT family
RIMD111065_RS21975	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
RIMD111065_RS21980	COG3161	chorismate lyase activity
RIMD111065_RS21985	COG1580	Controls the rotational direction of flagella during chemotaxis
RIMD111065_RS22000	COG0604	alcohol dehydrogenase
RIMD111065_RS22005	COG1609	Transcriptional regulator
RIMD111065_RS22025	COG1519	Transferase
RIMD111065_RS22030	COG0859	PFAM glycosyl transferase family 9
RIMD111065_RS22035	COG0463	Glycosyl transferase, family 2
RIMD111065_RS22040	COG0859	PFAM glycosyl transferase family 9
RIMD111065_RS22045	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
RIMD111065_RS22050	COG2990	Protein conserved in bacteria
RIMD111065_RS22055	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
RIMD111065_RS22065	COG0267	Belongs to the bacterial ribosomal protein bL33 family
RIMD111065_RS22070	COG0227	Belongs to the bacterial ribosomal protein bL28 family
RIMD111065_RS22075	COG2003	Belongs to the UPF0758 family
RIMD111065_RS22080	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
RIMD111065_RS22085	COG0756	dUTP diphosphatase activity
RIMD111065_RS22090	COG1309	transcriptional regulator
RIMD111065_RS22095	COG0668	transmembrane transport
RIMD111065_RS22105	COG0166	Belongs to the GPI family
RIMD111065_RS22110	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
RIMD111065_RS22115	COG0583	DNA-binding transcription factor activity
RIMD111065_RS22130	COG0045	succinate-CoA ligase (ADP-forming) activity
RIMD111065_RS22130	COG1042	CoA-binding domain protein
RIMD111065_RS22130	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
RIMD111065_RS22155	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
RIMD111065_RS22160	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
RIMD111065_RS22165	COG1739	Uncharacterized protein family UPF0029
RIMD111065_RS22170	COG0006	proline dipeptidase activity
RIMD111065_RS22175	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
RIMD111065_RS22180	COG1250	3-hydroxyacyl-CoA dehydrogenase
RIMD111065_RS22180	COG1024	Enoyl-CoA hydratase
RIMD111065_RS22185	COG0183	Belongs to the thiolase family
RIMD111065_RS22210	COG0425	Belongs to the sulfur carrier protein TusA family
RIMD111065_RS22215	COG0251	oxidation-reduction process
RIMD111065_RS22230	COG2885	chlorophyll binding
RIMD111065_RS22240	COG2818	Glycosylase
RIMD111065_RS22245	COG0752	glycyl-tRNA synthetase alpha subunit
RIMD111065_RS22250	COG0751	glycine-tRNA ligase activity
RIMD111065_RS22265	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
RIMD111065_RS22285	COG0814	amino acid
RIMD111065_RS22290	COG0348	domain, Protein
RIMD111065_RS22300	COG0446	pyridine nucleotide-disulphide oxidoreductase
RIMD111065_RS22305	COG1773	rubredoxin
RIMD111065_RS22305	COG0426	domain, Protein
RIMD111065_RS22310	COG3604	Transcriptional regulator
RIMD111065_RS22315	COG2188	Transcriptional regulator
RIMD111065_RS22330	COG1609	Transcriptional regulator
RIMD111065_RS22370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
RIMD111065_RS22395	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
RIMD111065_RS22410	COG3118	belongs to the thioredoxin family
RIMD111065_RS22415	COG0513	Belongs to the DEAD box helicase family
RIMD111065_RS22420	COG0248	Ppx GppA phosphatase
RIMD111065_RS22435	COG0742	ribosomal rna small subunit methyltransferase
RIMD111065_RS22455	COG0084	hydrolase, TatD family'
RIMD111065_RS22460	COG0805	protein transport
RIMD111065_RS22465	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
RIMD111065_RS22475	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
RIMD111065_RS22480	COG3165	ubiquinone biosynthetic process from chorismate
RIMD111065_RS22490	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
RIMD111065_RS22495	COG0402	S-adenosylhomocysteine deaminase activity
RIMD111065_RS22535	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
RIMD111065_RS22540	COG0848	biopolymer transport protein
RIMD111065_RS22545	COG0811	peptide transport
RIMD111065_RS22550	COG0811	peptide transport
RIMD111065_RS22560	COG2771	luxR family
RIMD111065_RS22565	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
RIMD111065_RS22570	COG1349	DNA-binding transcription factor activity
RIMD111065_RS22575	COG0745	RESPONSE REGULATOR receiver
RIMD111065_RS22580	COG2205	protein histidine kinase activity
RIMD111065_RS22590	COG4452	Inner membrane protein CreD
RIMD111065_RS22595	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
RIMD111065_RS22600	COG0355	proton-transporting ATP synthase activity, rotational mechanism
RIMD111065_RS22605	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
RIMD111065_RS22610	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
RIMD111065_RS22615	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
RIMD111065_RS22620	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
RIMD111065_RS22625	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
RIMD111065_RS22635	COG0356	it plays a direct role in the translocation of protons across the membrane
RIMD111065_RS22645	COG1475	DNA binding
RIMD111065_RS22650	COG1192	Involved in chromosome partitioning
RIMD111065_RS22655	COG0357	Ribosomal RNA small subunit methyltransferase G
RIMD111065_RS22660	COG0445	tRNA wobble uridine modification
RIMD111065_RS22665	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
RIMD111065_RS22670	COG4774	siderophore transport
RIMD111065_RS22675	COG4615	Cyclic peptide transporter
RIMD111065_RS22680	COG1120	ATPase activity
RIMD111065_RS22695	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
RIMD111065_RS22700	COG0706	membrane insertase activity
RIMD111065_RS22705	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
RIMD111065_RS22710	COG0594	ribonuclease P activity
RIMD111065_RS22715	COG0230	Belongs to the bacterial ribosomal protein bL34 family
RIMD111065_RS22720	COG1126	abc transporter atp-binding protein