locus-tag	class	description
LDP97_RS00015	COG0745	RESPONSE REGULATOR receiver
LDP97_RS00020	COG3104	oligopeptide transport
LDP97_RS00025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LDP97_RS00030	COG1555	photosystem II stabilization
LDP97_RS00040	COG2350	Protein conserved in bacteria
LDP97_RS00045	COG2917	probably involved in intracellular septation
LDP97_RS00050	COG0076	glutamate decarboxylase activity
LDP97_RS00055	COG1272	protein, Hemolysin III
LDP97_RS00060	COG0569	domain protein
LDP97_RS00060	COG2985	domain, Protein
LDP97_RS00095	COG0835	chemotaxis
LDP97_RS00095	COG0784	Response regulator, receiver
LDP97_RS00100	COG2755	lipolytic protein G-D-S-L family
LDP97_RS00105	COG4181	ATPase activity
LDP97_RS00110	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
LDP97_RS00115	COG1090	epimerase
LDP97_RS00120	COG2200	EAL domain
LDP97_RS00125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP97_RS00130	COG4935	Belongs to the peptidase S8 family
LDP97_RS00130	COG2234	aminopeptidase activity
LDP97_RS00135	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LDP97_RS00140	COG3171	Protein conserved in bacteria
LDP97_RS00145	COG2066	Belongs to the glutaminase family
LDP97_RS00150	COG2897	thiosulfate sulfurtransferase activity
LDP97_RS00155	COG1404	Belongs to the peptidase S8 family
LDP97_RS00165	COG1132	(ABC) transporter
LDP97_RS00190	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
LDP97_RS00195	COG5001	Diguanylate cyclase
LDP97_RS00195	COG3300	MHYT domain
LDP97_RS00215	COG4628	conserved protein (DUF2132)
LDP97_RS00220	COG0688	phosphatidylethanolamine metabolic process
LDP97_RS00225	COG1162	GTPase activity
LDP97_RS00230	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
LDP97_RS00270	COG1278	Cold shock
LDP97_RS00280	COG0840	transmembrane signaling receptor activity
LDP97_RS00285	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDP97_RS00290	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDP97_RS00295	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDP97_RS00330	COG0848	biopolymer transport protein
LDP97_RS00335	COG0811	peptide transport
LDP97_RS00340	COG0811	peptide transport
LDP97_RS00355	COG4174	ABC transporter (Permease)
LDP97_RS00360	COG4239	(ABC) transporter, permease
LDP97_RS00370	COG0444	Belongs to the ABC transporter superfamily
LDP97_RS00375	COG4608	Belongs to the ABC transporter superfamily
LDP97_RS00380	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDP97_RS00385	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
LDP97_RS00390	COG1073	alpha beta
LDP97_RS00405	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDP97_RS00430	COG0243	molybdopterin cofactor binding
LDP97_RS00445	COG1116	anion transmembrane transporter activity
LDP97_RS00445	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
LDP97_RS00450	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
LDP97_RS00455	COG1116	anion transmembrane transporter activity
LDP97_RS00460	COG2146	nitrite reductase [NAD(P)H] activity
LDP97_RS00460	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDP97_RS00465	COG2146	nitrite reductase [NAD(P)H] activity
LDP97_RS00465	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDP97_RS00470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP97_RS00475	COG2313	pseudouridylate synthase activity
LDP97_RS00485	COG1858	cytochrome C peroxidase
LDP97_RS00520	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDP97_RS00525	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDP97_RS00550	COG2986	histidine ammonia-lyase
LDP97_RS00575	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDP97_RS00585	COG1028	Short-chain dehydrogenase reductase Sdr
LDP97_RS00600	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDP97_RS00615	COG2966	Psort location CytoplasmicMembrane, score
LDP97_RS00620	COG3610	response to peptide
LDP97_RS00630	COG4175	Glycine betaine
LDP97_RS00635	COG4176	ABC-type proline glycine betaine transport system permease component
LDP97_RS00640	COG2113	Glycine betaine
LDP97_RS00645	COG0175	sulfate reduction
LDP97_RS00650	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDP97_RS00655	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDP97_RS00660	COG0384	phenazine biosynthesis protein PhzF
LDP97_RS00665	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDP97_RS00680	COG0786	glutamate:sodium symporter activity
LDP97_RS00685	COG0252	asparaginase activity
LDP97_RS00690	COG3139	Protein of unknown function (DUF1315)
LDP97_RS00710	COG0616	signal peptide processing
LDP97_RS00715	COG1902	pentaerythritol trinitrate reductase activity
LDP97_RS00715	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDP97_RS00720	COG0778	Nitroreductase
LDP97_RS00735	COG2264	protein methyltransferase activity
LDP97_RS00740	COG0604	alcohol dehydrogenase
LDP97_RS00745	COG0583	DNA-binding transcription factor activity
LDP97_RS00750	COG1263	PTS System
LDP97_RS00750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS00750	COG2190	(PTS) system
LDP97_RS00755	COG4145	pantothenate transmembrane transporter activity
LDP97_RS00765	COG0439	Biotin carboxylase
LDP97_RS00770	COG0511	ligase activity, forming carbon-carbon bonds
LDP97_RS00775	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LDP97_RS00780	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDP97_RS00790	COG3300	MHYT domain
LDP97_RS00790	COG5001	Diguanylate cyclase
LDP97_RS00810	COG3381	protein complex oligomerization
LDP97_RS00825	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDP97_RS00840	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDP97_RS00845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDP97_RS00845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LDP97_RS00865	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LDP97_RS00870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDP97_RS00875	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
LDP97_RS00880	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
LDP97_RS00885	COG4172	Belongs to the ABC transporter superfamily
LDP97_RS00895	COG0601	transmembrane transport
LDP97_RS00905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LDP97_RS00910	COG0142	geranyltranstransferase activity
LDP97_RS00915	COG1722	exodeoxyribonuclease VII activity
LDP97_RS00920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LDP97_RS00925	COG1360	Flagellar Motor Protein
LDP97_RS00940	COG1534	Rna-binding protein
LDP97_RS00945	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LDP97_RS00955	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
LDP97_RS00960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDP97_RS00965	COG0149	triose-phosphate isomerase activity
LDP97_RS00970	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDP97_RS00985	COG0779	Required for maturation of 30S ribosomal subunits
LDP97_RS00990	COG0195	Participates in both transcription termination and antitermination
LDP97_RS00995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDP97_RS01000	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDP97_RS01005	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LDP97_RS01010	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDP97_RS01015	COG1185	polyribonucleotide nucleotidyltransferase activity
LDP97_RS01030	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
LDP97_RS01040	COG0114	fumarate hydratase activity
LDP97_RS01050	COG1966	Carbon starvation protein
LDP97_RS01055	COG3279	Response regulator of the LytR AlgR family
LDP97_RS01125	COG0312	modulator of DNA gyrase
LDP97_RS01130	COG0312	modulator of DNA gyrase
LDP97_RS01140	COG4974	Belongs to the 'phage' integrase family
LDP97_RS01145	COG1970	mechanosensitive ion channel activity
LDP97_RS01150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDP97_RS01160	COG0789	Transcriptional regulator
LDP97_RS01180	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDP97_RS01185	COG3545	Serine hydrolase
LDP97_RS01195	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LDP97_RS01200	COG0321	lipoyl(octanoyl) transferase activity
LDP97_RS01205	COG2921	Belongs to the UPF0250 family
LDP97_RS01215	COG1686	Belongs to the peptidase S11 family
LDP97_RS01220	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
LDP97_RS01225	COG2951	lytic endotransglycosylase activity
LDP97_RS01230	COG0772	Belongs to the SEDS family
LDP97_RS01235	COG0772	Belongs to the SEDS family
LDP97_RS01240	COG0768	penicillin binding
LDP97_RS01245	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LDP97_RS01250	COG0799	negative regulation of ribosome biogenesis
LDP97_RS01255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDP97_RS01270	COG0495	leucyl-tRNA aminoacylation
LDP97_RS01275	COG2888	peptidyl-tyrosine sulfation
LDP97_RS01280	COG0815	Transfers the fatty acyl group on membrane lipoproteins
LDP97_RS01285	COG4535	Mg2 and Co2 transporter CorC
LDP97_RS01290	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LDP97_RS01295	COG1702	phosphate starvation-inducible protein PhoH
LDP97_RS01300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDP97_RS01305	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDP97_RS01310	COG1335	isochorismatase
LDP97_RS01320	COG3706	GGDEF domain
LDP97_RS01335	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP97_RS01355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDP97_RS01365	COG3647	Membrane
LDP97_RS01370	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDP97_RS01380	COG0516	GMP reductase activity
LDP97_RS01390	COG0642	Histidine kinase
LDP97_RS01430	COG3214	Protein conserved in bacteria
LDP97_RS01455	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
LDP97_RS01460	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
LDP97_RS01465	COG1053	succinate dehydrogenase
LDP97_RS01475	COG0584	glycerophosphoryl diester phosphodiesterase
LDP97_RS01480	COG1511	domain protein
LDP97_RS01480	COG3264	Mechanosensitive ion channel
LDP97_RS01490	COG0739	heme binding
LDP97_RS01505	COG0583	DNA-binding transcription factor activity
LDP97_RS01525	COG0583	DNA-binding transcription factor activity
LDP97_RS01530	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LDP97_RS01560	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LDP97_RS01565	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LDP97_RS01575	COG0338	D12 class N6 adenine-specific DNA methyltransferase
LDP97_RS01580	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDP97_RS01590	COG0180	Tryptophanyl-tRNA synthetase
LDP97_RS01605	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDP97_RS01615	COG1012	belongs to the aldehyde dehydrogenase family
LDP97_RS01625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP97_RS01635	COG0674	pyruvate-flavodoxin oxidoreductase activity
LDP97_RS01635	COG1013	pyruvate-flavodoxin oxidoreductase activity
LDP97_RS01635	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDP97_RS01635	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LDP97_RS01645	COG0366	Alpha amylase catalytic
LDP97_RS01665	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
LDP97_RS01675	COG0471	metal ion transport
LDP97_RS01675	COG0490	domain, Protein
LDP97_RS01730	COG0012	GTP binding
LDP97_RS01735	COG0193	aminoacyl-tRNA hydrolase activity
LDP97_RS01740	COG0737	Belongs to the 5'-nucleotidase family
LDP97_RS01745	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDP97_RS01755	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LDP97_RS01760	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
LDP97_RS01765	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
LDP97_RS01770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LDP97_RS01775	COG2890	protein-(glutamine-N5) methyltransferase activity
LDP97_RS01785	COG2912	Transglutaminase-like superfamily
LDP97_RS01790	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LDP97_RS01795	COG1301	dicarboxylic acid transport
LDP97_RS01805	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDP97_RS01820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDP97_RS01825	COG1115	amino acid carrier protein
LDP97_RS01840	COG0714	Associated with various cellular activities
LDP97_RS01850	COG3104	oligopeptide transport
LDP97_RS01855	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LDP97_RS01860	COG1678	Uncharacterized ACR, COG1678
LDP97_RS01870	COG0189	ligase activity
LDP97_RS01875	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDP97_RS01885	COG3091	SprT-like family
LDP97_RS01895	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
LDP97_RS01900	COG3710	Transcriptional regulator
LDP97_RS01940	COG2200	EAL domain
LDP97_RS01960	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
LDP97_RS01965	COG0739	heme binding
LDP97_RS01970	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDP97_RS01975	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
LDP97_RS01975	COG3408	Glycogen debranching enzyme
LDP97_RS01985	COG1881	PFAM PEBP family protein
LDP97_RS01990	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDP97_RS01995	COG0583	DNA-binding transcription factor activity
LDP97_RS02005	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LDP97_RS02015	COG0583	DNA-binding transcription factor activity
LDP97_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
LDP97_RS02025	COG0616	signal peptide processing
LDP97_RS02030	COG3724	N-succinylarginine dihydrolase activity
LDP97_RS02050	COG0840	transmembrane signaling receptor activity
LDP97_RS02060	COG2971	BadF BadG BcrA BcrD
LDP97_RS02070	COG4608	Belongs to the ABC transporter superfamily
LDP97_RS02075	COG0444	Belongs to the ABC transporter superfamily
LDP97_RS02080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP97_RS02085	COG0601	transmembrane transport
LDP97_RS02090	COG4166	transmembrane transport
LDP97_RS02095	COG0784	Response regulator, receiver
LDP97_RS02095	COG2205	protein histidine kinase activity
LDP97_RS02125	COG3220	belongs to the UPF0276 family
LDP97_RS02155	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDP97_RS02160	COG1289	transmembrane transporter activity
LDP97_RS02165	COG0303	'Molybdopterin
LDP97_RS02170	COG0746	molybdenum cofactor guanylyltransferase activity
LDP97_RS02180	COG4662	Binding-protein-dependent transport system inner membrane component
LDP97_RS02190	COG2204	response regulator
LDP97_RS02195	COG3852	Histidine kinase
LDP97_RS02200	COG1910	domain protein
LDP97_RS02205	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDP97_RS02245	COG3383	formate dehydrogenase (NAD+) activity
LDP97_RS02245	COG3383	formate dehydrogenase (NAD+) activity
LDP97_RS02250	COG0437	4 iron, 4 sulfur cluster binding
LDP97_RS02265	COG0281	malic enzyme
LDP97_RS02285	COG2706	6-phosphogluconolactonase activity
LDP97_RS02295	COG3264	Mechanosensitive ion channel
LDP97_RS02295	COG1196	nuclear chromosome segregation
LDP97_RS02300	COG0469	pyruvate kinase activity
LDP97_RS02315	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDP97_RS02315	COG4651	solute:proton antiporter activity
LDP97_RS02325	COG2974	May be involved in recombination
LDP97_RS02335	COG0420	3'-5' exonuclease activity
LDP97_RS02340	COG0419	ATPase involved in DNA repair
LDP97_RS02355	COG3038	cytochrome b561
LDP97_RS02370	COG2190	(PTS) system
LDP97_RS02380	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS02385	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
LDP97_RS02390	COG0542	response to heat
LDP97_RS02405	COG1720	tRNA m6t6A37 methyltransferase activity
LDP97_RS02425	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
LDP97_RS02430	COG4988	ABC transporter
LDP97_RS02445	COG0745	RESPONSE REGULATOR receiver
LDP97_RS02455	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDP97_RS02470	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
LDP97_RS02475	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
LDP97_RS02485	COG0083	homoserine kinase activity
LDP97_RS02490	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDP97_RS02495	COG4319	ketosteroid isomerase
LDP97_RS02510	COG0488	(ABC) transporter
LDP97_RS02520	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDP97_RS02530	COG0813	purine-nucleoside phosphorylase activity
LDP97_RS02545	COG2205	protein histidine kinase activity
LDP97_RS02545	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS02550	COG3384	dioxygenase
LDP97_RS02560	COG1283	sodium-dependent phosphate transmembrane transporter activity
LDP97_RS02570	COG0531	amino acid
LDP97_RS02580	COG0531	amino acid
LDP97_RS02595	COG1396	sequence-specific DNA binding
LDP97_RS02595	COG1917	Cupin 2, conserved barrel domain protein
LDP97_RS02600	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP97_RS02620	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDP97_RS02625	COG2375	cellular response to nickel ion
LDP97_RS02635	COG1136	(ABC) transporter
LDP97_RS02635	COG0577	efflux transmembrane transporter activity
LDP97_RS02640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDP97_RS02650	COG1227	inorganic diphosphatase activity
LDP97_RS02655	COG0497	DNA recombination
LDP97_RS02660	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LDP97_RS02665	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LDP97_RS02670	COG0443	Heat shock 70 kDa protein
LDP97_RS02675	COG0484	heat shock protein binding
LDP97_RS02705	COG1285	pathogenesis
LDP97_RS02720	COG0640	Transcriptional regulator
LDP97_RS02750	COG0095	Lipoate-protein ligase
LDP97_RS02770	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP97_RS02775	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDP97_RS02795	COG0708	Exodeoxyribonuclease III
LDP97_RS02810	COG2211	Major facilitator Superfamily
LDP97_RS02855	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LDP97_RS02860	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LDP97_RS02865	COG1845	cytochrome c oxidase, subunit III
LDP97_RS02870	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LDP97_RS02875	COG0109	protoheme IX farnesyltransferase activity
LDP97_RS02880	COG2814	Major facilitator Superfamily
LDP97_RS02890	COG0784	Response regulator, receiver
LDP97_RS02890	COG2205	protein histidine kinase activity
LDP97_RS02890	COG2198	Histidine kinase
LDP97_RS02895	COG1879	ABC-type sugar transport system periplasmic component
LDP97_RS02905	COG0745	RESPONSE REGULATOR receiver
LDP97_RS02910	COG3005	denitrification pathway
LDP97_RS02920	COG3381	protein complex oligomerization
LDP97_RS02960	COG2003	Belongs to the UPF0758 family
LDP97_RS03000	COG0583	DNA-binding transcription factor activity
LDP97_RS03015	COG0549	Belongs to the carbamate kinase family
LDP97_RS03020	COG1304	FMN binding
LDP97_RS03025	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LDP97_RS03030	COG1335	isochorismatase
LDP97_RS03050	COG3311	Transcriptional regulator
LDP97_RS03065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP97_RS03105	COG0159	tryptophan synthase activity
LDP97_RS03110	COG0133	tryptophan synthase activity
LDP97_RS03115	COG0135	phosphoribosylanthranilate isomerase activity
LDP97_RS03115	COG0134	indole-3-glycerol-phosphate synthase activity
LDP97_RS03120	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDP97_RS03125	COG0512	Glutamine amidotransferase of anthranilate synthase
LDP97_RS03125	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
LDP97_RS03130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
LDP97_RS03140	COG0009	L-threonylcarbamoyladenylate synthase
LDP97_RS03150	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LDP97_RS03160	COG1946	Acyl-CoA thioesterase
LDP97_RS03175	COG1309	transcriptional regulator
LDP97_RS03180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDP97_RS03185	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP97_RS03195	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LDP97_RS03215	COG2244	polysaccharide biosynthetic process
LDP97_RS03235	COG0110	maltose O-acetyltransferase activity
LDP97_RS03250	COG0297	glycogen (starch) synthase activity
LDP97_RS03255	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
LDP97_RS03260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDP97_RS03270	COG0662	Cupin 2, conserved barrel domain protein
LDP97_RS03270	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
LDP97_RS03285	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDP97_RS03290	COG1091	dTDP-4-dehydrorhamnose reductase activity
LDP97_RS03295	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
LDP97_RS03305	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
LDP97_RS03335	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDP97_RS03345	COG3132	Protein of unknown function, DUF480
LDP97_RS03385	COG1278	Cold shock
LDP97_RS03415	COG0697	spore germination
LDP97_RS03420	COG1349	DNA-binding transcription factor activity
LDP97_RS03425	COG1882	Formate acetyltransferase
LDP97_RS03430	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LDP97_RS03435	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LDP97_RS03465	COG0622	Phosphoesterase
LDP97_RS03480	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
LDP97_RS03485	COG0784	Response regulator, receiver
LDP97_RS03485	COG0835	chemotaxis
LDP97_RS03490	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
LDP97_RS03495	COG1815	bacterial-type flagellum-dependent cell motility
LDP97_RS03515	COG4787	bacterial-type flagellum-dependent cell motility
LDP97_RS03525	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
LDP97_RS03530	COG1706	bacterial-type flagellum-dependent cell motility
LDP97_RS03535	COG1705	Flagellar rod assembly protein muramidase FlgJ
LDP97_RS03535	COG3951	Flagellar rod assembly protein muramidase FlgJ
LDP97_RS03540	COG1256	bacterial-type flagellum assembly
LDP97_RS03550	COG2239	Acts as a magnesium transporter
LDP97_RS03560	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LDP97_RS03565	COG2716	regulation of RNA biosynthetic process
LDP97_RS03590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDP97_RS03595	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LDP97_RS03600	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDP97_RS03605	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDP97_RS03625	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
LDP97_RS03640	COG0590	tRNA wobble adenosine to inosine editing
LDP97_RS03645	COG0573	inorganic phosphate transmembrane transporter activity
LDP97_RS03650	COG0581	inorganic phosphate transmembrane transporter activity
LDP97_RS03655	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDP97_RS03660	COG0704	Plays a role in the regulation of phosphate uptake
LDP97_RS03665	COG1253	flavin adenine dinucleotide binding
LDP97_RS03680	COG0531	amino acid
LDP97_RS03695	COG1126	abc transporter atp-binding protein
LDP97_RS03700	COG0765	amino acid transport
LDP97_RS03705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS03715	COG2271	Major facilitator Superfamily
LDP97_RS03730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDP97_RS03755	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LDP97_RS03760	COG0477	Major facilitator Superfamily
LDP97_RS03765	COG0123	including yeast histone deacetylase and acetoin utilization protein
LDP97_RS03775	COG1199	ATP-dependent helicase activity
LDP97_RS03790	COG1448	Aminotransferase
LDP97_RS03795	COG0433	COG0433 Predicted ATPase
LDP97_RS03885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDP97_RS03895	COG1522	sequence-specific DNA binding
LDP97_RS03935	COG5642	Protein of unknown function (DUF2384)
LDP97_RS03950	COG2916	Histone family protein nucleoid-structuring protein H-NS
LDP97_RS04000	COG1663	tetraacyldisaccharide 4'-kinase activity
LDP97_RS04005	COG2835	tetraacyldisaccharide 4'-kinase activity
LDP97_RS04010	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LDP97_RS04015	COG2197	response regulator
LDP97_RS04020	COG0322	excinuclease ABC activity
LDP97_RS04045	COG0582	viral genome integration into host DNA
LDP97_RS04095	COG3962	Belongs to the TPP enzyme family
LDP97_RS04105	COG0673	inositol 2-dehydrogenase activity
LDP97_RS04110	COG1879	ABC-type sugar transport system periplasmic component
LDP97_RS04120	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDP97_RS04125	COG0673	inositol 2-dehydrogenase activity
LDP97_RS04130	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP97_RS04140	COG3718	enzyme involved in inositol metabolism
LDP97_RS04230	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LDP97_RS04235	COG0437	4 iron, 4 sulfur cluster binding
LDP97_RS04240	COG3301	Polysulphide reductase, NrfD
LDP97_RS04245	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LDP97_RS04255	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDP97_RS04260	COG0215	cysteine-tRNA ligase activity
LDP97_RS04280	COG2203	Gaf domain
LDP97_RS04280	COG2199	diguanylate cyclase activity
LDP97_RS04310	COG2119	membrane
LDP97_RS04315	COG0023	Translation Initiation Factor
LDP97_RS04340	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDP97_RS04355	COG2205	protein histidine kinase activity
LDP97_RS04355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS04365	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
LDP97_RS04375	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDP97_RS04380	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LDP97_RS04385	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDP97_RS04390	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LDP97_RS04395	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDP97_RS04410	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LDP97_RS04415	COG0505	Belongs to the CarA family
LDP97_RS04420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDP97_RS04425	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDP97_RS04455	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP97_RS04460	COG0513	Belongs to the DEAD box helicase family
LDP97_RS04470	COG4104	PAAR repeat-containing protein
LDP97_RS04485	COG0789	Transcriptional regulator
LDP97_RS04500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS04505	COG0765	amino acid transport
LDP97_RS04510	COG1126	abc transporter atp-binding protein
LDP97_RS04515	COG0493	'glutamate synthase
LDP97_RS04520	COG0070	glutamate synthase
LDP97_RS04520	COG0069	glutamate synthase activity
LDP97_RS04520	COG0067	glutamate synthase
LDP97_RS04525	COG1242	4 iron, 4 sulfur cluster binding
LDP97_RS04590	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LDP97_RS04595	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LDP97_RS04595	COG0574	Belongs to the PEP-utilizing enzyme family
LDP97_RS04630	COG3038	cytochrome b561
LDP97_RS04645	COG1464	Belongs to the NlpA lipoprotein family
LDP97_RS04650	COG0671	phosphoesterase, PA-phosphatase related
LDP97_RS04655	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDP97_RS04660	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDP97_RS04670	COG0101	tRNA pseudouridine synthase activity
LDP97_RS04675	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LDP97_RS04680	COG0285	dihydrofolate synthase activity
LDP97_RS04685	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
LDP97_RS04690	COG2920	part of a sulfur-relay system
LDP97_RS04695	COG1289	transmembrane transporter activity
LDP97_RS04700	COG0670	Belongs to the BI1 family
LDP97_RS04765	COG2003	Belongs to the UPF0758 family
LDP97_RS04825	COG1074	ATP-dependent DNA helicase activity
LDP97_RS04830	COG1196	nuclear chromosome segregation
LDP97_RS04840	COG3311	Transcriptional regulator
LDP97_RS04860	COG3501	Rhs element vgr protein
LDP97_RS04895	COG0582	viral genome integration into host DNA
LDP97_RS04910	COG2194	sulfuric ester hydrolase activity
LDP97_RS04920	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LDP97_RS04920	COG0392	lysyltransferase activity
LDP97_RS04930	COG0840	transmembrane signaling receptor activity
LDP97_RS04935	COG5001	Diguanylate cyclase
LDP97_RS04940	COG0564	pseudouridine synthase activity
LDP97_RS04955	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
LDP97_RS04965	COG0625	glutathione transferase activity
LDP97_RS04970	COG0625	glutathione transferase activity
LDP97_RS04980	COG0367	asparagine synthase
LDP97_RS04990	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LDP97_RS04990	COG4651	solute:proton antiporter activity
LDP97_RS04995	COG0647	UMP catabolic process
LDP97_RS05000	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDP97_RS05005	COG1902	pentaerythritol trinitrate reductase activity
LDP97_RS05010	COG1253	flavin adenine dinucleotide binding
LDP97_RS05020	COG0277	FAD linked oxidase domain protein
LDP97_RS05020	COG0247	lactate metabolic process
LDP97_RS05030	COG2050	protein possibly involved in aromatic compounds catabolism
LDP97_RS05040	COG2056	Na+-H+ antiporter family
LDP97_RS05045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDP97_RS05060	COG0346	lactoylglutathione lyase activity
LDP97_RS05065	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
LDP97_RS05070	COG4660	Part of a membrane complex involved in electron transport
LDP97_RS05075	COG4659	FMN binding
LDP97_RS05080	COG4658	electron transport chain
LDP97_RS05090	COG2878	Part of a membrane complex involved in electron transport
LDP97_RS05095	COG4657	Part of a membrane complex involved in electron transport
LDP97_RS05100	COG0697	spore germination
LDP97_RS05120	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LDP97_RS05125	COG1288	antiporter activity
LDP97_RS05130	COG0436	Aminotransferase
LDP97_RS05140	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LDP97_RS05145	COG2027	D-alanyl-D-alanine carboxypeptidase
LDP97_RS05150	COG1061	Type III restriction enzyme res subunit
LDP97_RS05155	COG1566	PFAM secretion protein HlyD family protein
LDP97_RS05165	COG1966	Carbon starvation protein
LDP97_RS05170	COG3279	Response regulator of the LytR AlgR family
LDP97_RS05175	COG3275	phosphorelay sensor kinase activity
LDP97_RS05180	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDP97_RS05180	COG2199	diguanylate cyclase activity
LDP97_RS05185	COG1012	belongs to the aldehyde dehydrogenase family
LDP97_RS05185	COG1454	alcohol dehydrogenase
LDP97_RS05195	COG2095	MarC family integral membrane protein
LDP97_RS05205	COG0601	transmembrane transport
LDP97_RS05210	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP97_RS05230	COG0861	Integral membrane protein TerC family
LDP97_RS05235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDP97_RS05245	COG1301	dicarboxylic acid transport
LDP97_RS05260	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDP97_RS05275	COG0537	adenosine 5'-monophosphoramidase activity
LDP97_RS05310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDP97_RS05315	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDP97_RS05325	COG2354	Protein conserved in bacteria
LDP97_RS05340	COG2233	PERMEase
LDP97_RS05345	COG3150	esterase
LDP97_RS05350	COG1252	NADH dehydrogenase
LDP97_RS05370	COG0393	Putative heavy-metal-binding
LDP97_RS05380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDP97_RS05380	COG1648	precorrin-2 dehydrogenase activity
LDP97_RS05400	COG4667	esterase of the alpha-beta hydrolase superfamily
LDP97_RS05405	COG1619	proteins homologs of microcin C7 resistance protein MccF
LDP97_RS05410	COG1368	sulfuric ester hydrolase activity
LDP97_RS05420	COG0527	aspartate kinase activity
LDP97_RS05425	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDP97_RS05425	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
LDP97_RS05430	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDP97_RS05450	COG0596	Alpha beta hydrolase
LDP97_RS05455	COG0346	lactoylglutathione lyase activity
LDP97_RS05465	COG0583	DNA-binding transcription factor activity
LDP97_RS05470	COG1620	l-lactate permease
LDP97_RS05480	COG1139	Iron-sulfur cluster binding protein
LDP97_RS05510	COG0577	efflux transmembrane transporter activity
LDP97_RS05515	COG1136	(ABC) transporter
LDP97_RS05525	COG2814	Major facilitator Superfamily
LDP97_RS05545	COG0672	)-iron permease
LDP97_RS05575	COG0659	secondary active sulfate transmembrane transporter activity
LDP97_RS05610	COG1629	transport
LDP97_RS05610	COG4771	TonB-dependent receptor
LDP97_RS05640	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDP97_RS05645	COG0840	transmembrane signaling receptor activity
LDP97_RS05655	COG2201	protein-glutamate methylesterase activity
LDP97_RS05665	COG0835	chemotaxis
LDP97_RS05670	COG0840	transmembrane signaling receptor activity
LDP97_RS05670	COG3290	protein histidine kinase activity
LDP97_RS05675	COG0643	Histidine kinase
LDP97_RS05675	COG2198	Histidine kinase
LDP97_RS05685	COG0745	RESPONSE REGULATOR receiver
LDP97_RS05690	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
LDP97_RS05695	COG0437	4 iron, 4 sulfur cluster binding
LDP97_RS05700	COG5557	Pfam Polysulphide reductase, NrfD
LDP97_RS05705	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
LDP97_RS05710	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LDP97_RS05715	COG1773	rubredoxin
LDP97_RS05720	COG0747	negative chemotaxis
LDP97_RS05725	COG0601	transmembrane transport
LDP97_RS05730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP97_RS05735	COG0444	Belongs to the ABC transporter superfamily
LDP97_RS05740	COG3842	ATPase activity
LDP97_RS05745	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
LDP97_RS05755	COG0375	protein maturation
LDP97_RS05760	COG0309	Hydrogenase expression formation protein (HypE)
LDP97_RS05770	COG0298	carbon dioxide binding
LDP97_RS05775	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
LDP97_RS05785	COG1921	L-seryl-tRNASec selenium transferase activity
LDP97_RS05795	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
LDP97_RS05805	COG3260	NADH ubiquinone oxidoreductase 20
LDP97_RS05810	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDP97_RS05815	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
LDP97_RS05815	COG3261	NADH dehydrogenase
LDP97_RS05820	COG0650	Formate hydrogenlyase subunit 4
LDP97_RS05825	COG0651	ATP synthesis coupled electron transport
LDP97_RS05830	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDP97_RS05835	COG3158	transport of potassium into the cell
LDP97_RS05850	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDP97_RS05875	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LDP97_RS05880	COG0326	Molecular chaperone. Has ATPase activity
LDP97_RS05885	COG0563	adenylate kinase activity
LDP97_RS05890	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
LDP97_RS05900	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP97_RS05920	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDP97_RS05940	COG1021	2,3-dihydroxybenzoate-AMP ligase
LDP97_RS05945	COG1535	isochorismatase
LDP97_RS05945	COG3433	isochorismatase activity
LDP97_RS05950	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDP97_RS05955	COG1028	Short-chain dehydrogenase reductase Sdr
LDP97_RS05965	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
LDP97_RS05970	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
LDP97_RS05975	COG2977	Belongs to the P-Pant transferase superfamily
LDP97_RS05980	COG1120	ATPase activity
LDP97_RS05985	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP97_RS05990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP97_RS05995	COG4771	TonB-dependent receptor
LDP97_RS06035	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDP97_RS06040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LDP97_RS06045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDP97_RS06060	COG1570	exodeoxyribonuclease VII activity
LDP97_RS06065	COG0697	spore germination
LDP97_RS06085	COG3158	transport of potassium into the cell
LDP97_RS06090	COG0516	GMP reductase activity
LDP97_RS06090	COG0517	IMP dehydrogenase activity
LDP97_RS06095	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDP97_RS06095	COG0519	Catalyzes the synthesis of GMP from XMP
LDP97_RS06100	COG0582	viral genome integration into host DNA
LDP97_RS06155	COG2169	Transcriptional regulator
LDP97_RS06155	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDP97_RS06180	COG2062	phosphohistidine phosphatase, SixA
LDP97_RS06190	COG0697	spore germination
LDP97_RS06195	COG4166	transmembrane transport
LDP97_RS06200	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
LDP97_RS06205	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LDP97_RS06215	COG4591	ABC-type transport system involved in lipoprotein release permease component
LDP97_RS06220	COG1136	(ABC) transporter
LDP97_RS06225	COG4591	ABC-type transport system involved in lipoprotein release permease component
LDP97_RS06230	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LDP97_RS06240	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDP97_RS06245	COG0740	serine-type endopeptidase activity
LDP97_RS06250	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LDP97_RS06255	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LDP97_RS06260	COG0776	regulation of translation
LDP97_RS06265	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDP97_RS06270	COG0488	(ABC) transporter
LDP97_RS06275	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP97_RS06280	COG3162	membrane
LDP97_RS06295	COG1024	Enoyl-CoA hydratase
LDP97_RS06330	COG1115	amino acid carrier protein
LDP97_RS06345	COG1584	GPR1 FUN34 yaaH family protein
LDP97_RS06385	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
LDP97_RS06390	COG1960	acyl-CoA dehydrogenase activity
LDP97_RS06400	COG1960	acyl-CoA dehydrogenase activity
LDP97_RS06405	COG1024	Enoyl-CoA hydratase
LDP97_RS06410	COG1024	Enoyl-CoA hydratase
LDP97_RS06420	COG1028	Short-chain dehydrogenase reductase Sdr
LDP97_RS06430	COG0730	response to heat
LDP97_RS06455	COG5001	Diguanylate cyclase
LDP97_RS06455	COG5002	protein histidine kinase activity
LDP97_RS06475	COG2003	Belongs to the UPF0758 family
LDP97_RS06490	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LDP97_RS06515	COG1073	alpha beta
LDP97_RS06520	COG0823	Involved in the tonB-independent uptake of proteins
LDP97_RS06520	COG1506	peptidase
LDP97_RS06525	COG0702	epimerase
LDP97_RS06530	COG0583	DNA-binding transcription factor activity
LDP97_RS06535	COG0667	Aldo Keto reductase
LDP97_RS06550	COG3706	GGDEF domain
LDP97_RS06555	COG0583	DNA-binding transcription factor activity
LDP97_RS06560	COG2723	6-phospho-beta-galactosidase activity
LDP97_RS06565	COG5001	Diguanylate cyclase
LDP97_RS06565	COG3300	MHYT domain
LDP97_RS06575	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDP97_RS06580	COG1028	Short-chain dehydrogenase reductase Sdr
LDP97_RS06585	COG0583	DNA-binding transcription factor activity
LDP97_RS06590	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LDP97_RS06595	COG0673	inositol 2-dehydrogenase activity
LDP97_RS06600	COG0583	DNA-binding transcription factor activity
LDP97_RS06610	COG1560	Kdo2-lipid A biosynthetic process
LDP97_RS06615	COG1560	Kdo2-lipid A biosynthetic process
LDP97_RS06640	COG0417	DNA replication proofreading
LDP97_RS06670	COG0534	Mate efflux family protein
LDP97_RS06680	COG0307	riboflavin synthase, alpha
LDP97_RS06690	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP97_RS06695	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LDP97_RS06700	COG0697	spore germination
LDP97_RS06705	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
LDP97_RS06745	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDP97_RS06750	COG3099	Belongs to the UPF0263 family
LDP97_RS06755	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
LDP97_RS06760	COG2894	cell division
LDP97_RS06765	COG0850	regulation of cytokinetic process
LDP97_RS06770	COG3100	YcgL domain-containing protein
LDP97_RS06775	COG2951	lytic endotransglycosylase activity
LDP97_RS06780	COG1760	l-serine dehydratase
LDP97_RS06785	COG1760	l-serine dehydratase
LDP97_RS06790	COG3123	guanosine phosphorylase activity
LDP97_RS06810	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
LDP97_RS06830	COG1595	DNA-templated transcription, initiation
LDP97_RS06860	COG0714	Associated with various cellular activities
LDP97_RS06865	COG0183	Belongs to the thiolase family
LDP97_RS06870	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDP97_RS06870	COG1024	Enoyl-CoA hydratase
LDP97_RS06890	COG4383	Mu-like prophage protein gp29
LDP97_RS06925	COG4388	Caudovirus prohead serine protease
LDP97_RS06930	COG3829	transcription factor binding
LDP97_RS06935	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDP97_RS06940	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LDP97_RS06945	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDP97_RS06955	COG0549	Belongs to the carbamate kinase family
LDP97_RS06960	COG0697	spore germination
LDP97_RS06965	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
LDP97_RS06965	COG3608	succinylglutamate desuccinylase aspartoacylase
LDP97_RS06970	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LDP97_RS06980	COG0493	'glutamate synthase
LDP97_RS06980	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDP97_RS06985	COG0402	S-adenosylhomocysteine deaminase activity
LDP97_RS06990	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LDP97_RS06995	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LDP97_RS06995	COG2080	2 iron, 2 sulfur cluster binding
LDP97_RS07000	COG2233	PERMEase
LDP97_RS07005	COG0402	S-adenosylhomocysteine deaminase activity
LDP97_RS07010	COG2252	PERMEase
LDP97_RS07015	COG1529	Aldehyde oxidase and xanthine dehydrogenase
LDP97_RS07020	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
LDP97_RS07025	COG2080	2 iron, 2 sulfur cluster binding
LDP97_RS07035	COG3134	Outer membrane lipoprotein
LDP97_RS07045	COG1288	antiporter activity
LDP97_RS07050	COG0318	PFAM AMP-dependent synthetase and ligase
LDP97_RS07055	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
LDP97_RS07055	COG0140	phosphoribosyl-ATP diphosphatase activity
LDP97_RS07060	COG0107	imidazoleglycerol-phosphate synthase activity
LDP97_RS07065	COG0784	Response regulator, receiver
LDP97_RS07065	COG2198	Histidine kinase
LDP97_RS07065	COG2205	protein histidine kinase activity
LDP97_RS07070	COG2199	diguanylate cyclase activity
LDP97_RS07075	COG3437	response regulator, receiver
LDP97_RS07080	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
LDP97_RS07085	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LDP97_RS07090	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDP97_RS07090	COG0131	Imidazoleglycerol-phosphate dehydratase
LDP97_RS07095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
LDP97_RS07100	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
LDP97_RS07105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
LDP97_RS07115	COG1199	ATP-dependent helicase activity
LDP97_RS07120	COG1214	PFAM Peptidase M22, glycoprotease
LDP97_RS07130	COG2226	methyltransferase
LDP97_RS07130	COG0596	Alpha beta hydrolase
LDP97_RS07130	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
LDP97_RS07135	COG0318	PFAM AMP-dependent synthetase and ligase
LDP97_RS07140	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LDP97_RS07270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
LDP97_RS07280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDP97_RS07285	COG2832	Protein of unknown function (DUF454)
LDP97_RS07290	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDP97_RS07300	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LDP97_RS07305	COG0582	viral genome integration into host DNA
LDP97_RS07330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LDP97_RS07435	COG0753	catalase activity
LDP97_RS07460	COG3645	SOS response
LDP97_RS07460	COG3646	Phage regulatory protein
LDP97_RS07485	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDP97_RS07490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDP97_RS07510	COG2916	Histone family protein nucleoid-structuring protein H-NS
LDP97_RS07675	COG0617	tRNA 3'-terminal CCA addition
LDP97_RS07675	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LDP97_RS07675	COG0517	IMP dehydrogenase activity
LDP97_RS07680	COG1643	Atp-dependent helicase
LDP97_RS07690	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LDP97_RS07700	COG3437	response regulator, receiver
LDP97_RS07705	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP97_RS07710	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
LDP97_RS07715	COG0709	Synthesizes selenophosphate from selenide and ATP
LDP97_RS07730	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDP97_RS07735	COG0840	transmembrane signaling receptor activity
LDP97_RS07740	COG1254	Belongs to the acylphosphatase family
LDP97_RS07745	COG0625	glutathione transferase activity
LDP97_RS07750	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDP97_RS07750	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDP97_RS07755	COG0489	protein tyrosine kinase activity
LDP97_RS07760	COG0572	uridine kinase
LDP97_RS07765	COG0717	Belongs to the dCTP deaminase family
LDP97_RS07770	COG0306	phosphate transporter
LDP97_RS07775	COG1530	ribonuclease E activity
LDP97_RS07780	COG0564	pseudouridine synthase activity
LDP97_RS07790	COG0424	maF-like protein
LDP97_RS07795	COG2814	Major facilitator Superfamily
LDP97_RS07810	COG1399	metal-binding, possibly nucleic acid-binding protein
LDP97_RS07815	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LDP97_RS07820	COG0416	fatty acid biosynthetic process
LDP97_RS07825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDP97_RS07835	COG1028	Short-chain dehydrogenase reductase Sdr
LDP97_RS07840	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDP97_RS07850	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LDP97_RS07855	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LDP97_RS07860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDP97_RS07865	COG0470	DNA polymerase III
LDP97_RS07870	COG0084	hydrolase, TatD family'
LDP97_RS07890	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LDP97_RS07890	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDP97_RS07895	COG3008	intermembrane lipid transfer
LDP97_RS07900	COG2995	paraquat-inducible protein a
LDP97_RS07910	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
LDP97_RS07915	COG0372	Belongs to the citrate synthase family
LDP97_RS07960	COG4221	oxidoreductase activity
LDP97_RS07970	COG3141	response to X-ray
LDP97_RS07980	COG1067	ATP-dependent peptidase activity
LDP97_RS07985	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDP97_RS08000	COG0488	(ABC) transporter
LDP97_RS08010	COG0116	Belongs to the methyltransferase superfamily
LDP97_RS08010	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LDP97_RS08020	COG0167	dihydroorotate dehydrogenase activity
LDP97_RS08025	COG2902	Dehydrogenase
LDP97_RS08035	COG0308	aminopeptidase N
LDP97_RS08045	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
LDP97_RS08050	COG1956	GAF domain-containing protein
LDP97_RS08060	COG3278	Belongs to the heme-copper respiratory oxidase family
LDP97_RS08075	COG2010	Cytochrome c
LDP97_RS08100	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDP97_RS08105	COG0589	response to stress
LDP97_RS08110	COG0037	tRNA processing
LDP97_RS08125	COG0625	glutathione transferase activity
LDP97_RS08130	COG1869	D-ribose catabolic process
LDP97_RS08135	COG1129	ABC transporter
LDP97_RS08140	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDP97_RS08145	COG1879	ABC-type sugar transport system periplasmic component
LDP97_RS08150	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP97_RS08155	COG1609	Transcriptional regulator
LDP97_RS08190	COG0776	regulation of translation
LDP97_RS08195	COG0072	phenylalanine-tRNA ligase activity
LDP97_RS08195	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDP97_RS08200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LDP97_RS08205	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDP97_RS08210	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LDP97_RS08215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LDP97_RS08220	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LDP97_RS08245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDP97_RS08255	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDP97_RS08260	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDP97_RS08265	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDP97_RS08270	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
LDP97_RS08275	COG3313	Fe-S protein
LDP97_RS08280	COG2942	2-epimerase
LDP97_RS08285	COG3716	PTS system mannose fructose sorbose family IID component
LDP97_RS08290	COG3715	PTS system
LDP97_RS08295	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS08295	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS08310	COG1609	Transcriptional regulator
LDP97_RS08315	COG2140	Oxalate decarboxylase
LDP97_RS08320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP97_RS08320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP97_RS08320	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
LDP97_RS08325	COG1105	Belongs to the carbohydrate kinase PfkB family
LDP97_RS08330	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS08330	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS08335	COG1609	Transcriptional regulator
LDP97_RS08340	COG0814	amino acid
LDP97_RS08350	COG5654	RES domain protein
LDP97_RS08360	COG0513	Belongs to the DEAD box helicase family
LDP97_RS08370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LDP97_RS08375	COG2890	protein-(glutamine-N5) methyltransferase activity
LDP97_RS08380	COG2840	Smr protein MutS2
LDP97_RS08390	COG3706	GGDEF domain
LDP97_RS08395	COG0588	phosphoglycerate mutase activity
LDP97_RS08420	COG2824	Alkylphosphonate utilization operon protein PhnA
LDP97_RS08435	COG0384	phenazine biosynthesis protein PhzF
LDP97_RS08450	COG0242	peptide deformylase activity
LDP97_RS08470	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LDP97_RS08475	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
LDP97_RS08485	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LDP97_RS08490	COG1434	Gram-negative-bacterium-type cell wall biogenesis
LDP97_RS08500	COG0205	6-phosphofructokinase activity
LDP97_RS08505	COG1473	amidohydrolase
LDP97_RS08510	COG1011	Hydrolase
LDP97_RS08515	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LDP97_RS08565	COG3593	DNA synthesis involved in DNA repair
LDP97_RS08580	COG0583	DNA-binding transcription factor activity
LDP97_RS08585	COG0730	response to heat
LDP97_RS08595	COG3148	PFAM DTW domain containing protein
LDP97_RS08605	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDP97_RS08615	COG0386	Belongs to the glutathione peroxidase family
LDP97_RS08620	COG0513	Belongs to the DEAD box helicase family
LDP97_RS08625	COG0456	acetyltransferase
LDP97_RS08635	COG1742	UPF0060 membrane protein
LDP97_RS08665	COG2329	Antibiotic biosynthesis monooxygenase
LDP97_RS08670	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LDP97_RS08690	COG3243	poly(R)-hydroxyalkanoic acid synthase
LDP97_RS08700	COG2501	S4 domain
LDP97_RS08710	COG1132	(ABC) transporter
LDP97_RS08715	COG1132	(ABC) transporter
LDP97_RS08725	COG3118	belongs to the thioredoxin family
LDP97_RS08730	COG0471	metal ion transport
LDP97_RS08735	COG0058	SHG alpha-glucan phosphorylase activity
LDP97_RS08765	COG0814	amino acid
LDP97_RS08770	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
LDP97_RS08775	COG0514	ATP-dependent DNA helicase (RecQ)
LDP97_RS08780	COG2766	serine protein kinase
LDP97_RS08790	COG2719	SpoVR family
LDP97_RS08795	COG2186	Transcriptional regulator
LDP97_RS08800	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDP97_RS08805	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LDP97_RS08810	COG0586	Pfam SNARE associated Golgi protein
LDP97_RS08820	COG0556	nucleotide-excision repair
LDP97_RS08830	COG0569	domain protein
LDP97_RS08830	COG2985	domain, Protein
LDP97_RS08835	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LDP97_RS08855	COG4565	transcriptional regulatory protein
LDP97_RS08860	COG3290	protein histidine kinase activity
LDP97_RS08865	COG1846	Transcriptional regulator
LDP97_RS08865	COG1940	carbohydrate kinase activity
LDP97_RS08870	COG0840	transmembrane signaling receptor activity
LDP97_RS08875	COG3012	SEC-C Motif Domain Protein
LDP97_RS08880	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
LDP97_RS08885	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
LDP97_RS08890	COG0247	lactate metabolic process
LDP97_RS08910	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
LDP97_RS08915	COG0437	4 iron, 4 sulfur cluster binding
LDP97_RS08920	COG3301	Polysulphide reductase, NrfD
LDP97_RS08925	COG1138	Cytochrome C-type biogenesis protein
LDP97_RS08935	COG4235	cytochrome complex assembly
LDP97_RS08935	COG3088	subunit of a heme lyase
LDP97_RS08940	COG1051	belongs to the nudix hydrolase family
LDP97_RS08950	COG3033	Beta-eliminating lyase
LDP97_RS08960	COG3046	protein related to deoxyribodipyrimidine photolyase
LDP97_RS08965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP97_RS08990	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LDP97_RS08995	COG0583	DNA-binding transcription factor activity
LDP97_RS09005	COG4774	siderophore transport
LDP97_RS09010	COG4977	sequence-specific DNA binding
LDP97_RS09020	COG0583	DNA-binding transcription factor activity
LDP97_RS09025	COG2910	NAD(P)H-binding
LDP97_RS09035	COG0626	cystathionine gamma-synthase activity
LDP97_RS09040	COG0612	Peptidase, M16
LDP97_RS09045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDP97_RS09055	COG1944	ATP diphosphatase activity
LDP97_RS09060	COG2116	formate transmembrane transporter activity
LDP97_RS09065	COG1882	Formate acetyltransferase
LDP97_RS09070	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP97_RS09080	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
LDP97_RS09090	COG1840	ABC-type Fe3 transport system, periplasmic component
LDP97_RS09095	COG3842	ATPase activity
LDP97_RS09105	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP97_RS09110	COG2983	Belongs to the UPF0260 family
LDP97_RS09125	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LDP97_RS09130	COG0045	succinate-CoA ligase (ADP-forming) activity
LDP97_RS09135	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDP97_RS09140	COG0567	Dehydrogenase, E1 component
LDP97_RS09150	COG1053	succinate dehydrogenase
LDP97_RS09155	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
LDP97_RS09180	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDP97_RS09185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP97_RS09185	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
LDP97_RS09195	COG3069	C4-dicarboxylate transmembrane transporter activity
LDP97_RS09210	COG1451	nucleotide metabolic process
LDP97_RS09225	COG0254	rRNA binding
LDP97_RS09230	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDP97_RS09240	COG0583	DNA-binding transcription factor activity
LDP97_RS09250	COG1172	Belongs to the binding-protein-dependent transport system permease family
LDP97_RS09260	COG1879	ABC-type sugar transport system periplasmic component
LDP97_RS09265	COG1069	ribulokinase activity
LDP97_RS09275	COG2160	L-arabinose isomerase activity
LDP97_RS09280	COG2925	Exonuclease
LDP97_RS09290	COG3345	alpha-galactosidase
LDP97_RS09295	COG1380	Effector of murein hydrolase LrgA
LDP97_RS09300	COG1346	cytolysis
LDP97_RS09305	COG0295	cytidine deaminase activity
LDP97_RS09310	COG1022	Amp-dependent synthetase and ligase
LDP97_RS09325	COG0861	Integral membrane protein TerC family
LDP97_RS09330	COG2885	chlorophyll binding
LDP97_RS09335	COG2199	diguanylate cyclase activity
LDP97_RS09355	COG2154	pterin-4-alpha-carbinolamine dehydratase
LDP97_RS09365	COG3768	UPF0283 membrane protein
LDP97_RS09370	COG3106	COG3106 Predicted ATPase
LDP97_RS09385	COG1842	Phage shock protein A
LDP97_RS09390	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
LDP97_RS09400	COG4168	peptide transport system, permease
LDP97_RS09405	COG4171	peptide transport system, permease
LDP97_RS09415	COG4172	Belongs to the ABC transporter superfamily
LDP97_RS09425	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LDP97_RS09430	COG1286	toxin biosynthetic process
LDP97_RS09435	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LDP97_RS09440	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LDP97_RS09445	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
LDP97_RS09450	COG1674	ftsk spoiiie
LDP97_RS09450	COG0531	amino acid
LDP97_RS09460	COG0686	Belongs to the AlaDH PNT family
LDP97_RS09465	COG0492	ferredoxin-NADP+ reductase activity
LDP97_RS09470	COG3706	GGDEF domain
LDP97_RS09475	COG3134	Outer membrane lipoprotein
LDP97_RS09480	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
LDP97_RS09485	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
LDP97_RS09490	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDP97_RS09495	COG0542	response to heat
LDP97_RS09500	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LDP97_RS09505	COG1278	Cold shock
LDP97_RS09510	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDP97_RS09550	COG3179	chitinase
LDP97_RS09585	COG1435	thymidine kinase activity
LDP97_RS09590	COG1757	Na H antiporter
LDP97_RS09595	COG2916	Histone family protein nucleoid-structuring protein H-NS
LDP97_RS09600	COG2096	Adenosyltransferase
LDP97_RS09605	COG3530	Putative quorum-sensing-regulated virulence factor
LDP97_RS09610	COG0602	queuosine metabolic process
LDP97_RS09615	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LDP97_RS09635	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
LDP97_RS09645	COG0776	regulation of translation
LDP97_RS09650	COG0539	negative regulation of cytoplasmic translation
LDP97_RS09655	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LDP97_RS09660	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDP97_RS09670	COG0583	DNA-binding transcription factor activity
LDP97_RS09690	COG0778	Nitroreductase
LDP97_RS09695	COG5001	Diguanylate cyclase
LDP97_RS09695	COG3300	MHYT domain
LDP97_RS09705	COG0583	DNA-binding transcription factor activity
LDP97_RS09710	COG3437	response regulator, receiver
LDP97_RS09735	COG4989	oxidoreductase activity
LDP97_RS09740	COG0724	RNA recognition motif
LDP97_RS09760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LDP97_RS09775	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LDP97_RS09780	COG1360	Flagellar Motor Protein
LDP97_RS09785	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDP97_RS09790	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDP97_RS09795	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDP97_RS09795	COG0649	NAD binding
LDP97_RS09810	COG1034	ATP synthesis coupled electron transport
LDP97_RS09815	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LDP97_RS09820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDP97_RS09825	COG0839	Belongs to the complex I subunit 6 family
LDP97_RS09830	COG0713	ATP synthesis coupled electron transport
LDP97_RS09840	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LDP97_RS09845	COG1007	ATP synthesis coupled electron transport
LDP97_RS09855	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDP97_RS09855	COG0047	phosphoribosylformylglycinamidine synthase activity
LDP97_RS09860	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
LDP97_RS09865	COG1645	bacterial-type flagellum-dependent swarming motility
LDP97_RS09870	COG1160	GTP binding
LDP97_RS09875	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDP97_RS09880	COG2976	Protein conserved in bacteria
LDP97_RS09885	COG0124	histidyl-tRNA synthetase
LDP97_RS09890	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LDP97_RS09905	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LDP97_RS09910	COG0105	UTP biosynthetic process
LDP97_RS09915	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LDP97_RS09925	COG0633	Ferredoxin
LDP97_RS09930	COG0443	Heat shock 70 kDa protein
LDP97_RS09935	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LDP97_RS09945	COG0822	iron-sulfur transferase activity
LDP97_RS09950	COG1104	cysteine desulfurase activity
LDP97_RS09970	COG3154	lipid carrier protein
LDP97_RS09975	COG0826	peptidase U32
LDP97_RS09980	COG0826	peptidase U32
LDP97_RS09995	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDP97_RS10000	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
LDP97_RS10005	COG1862	Preprotein translocase
LDP97_RS10010	COG0343	queuine tRNA-ribosyltransferase activity
LDP97_RS10015	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
LDP97_RS10020	COG0517	IMP dehydrogenase activity
LDP97_RS10030	COG3634	alkyl hydroperoxide reductase activity
LDP97_RS10050	COG1393	Belongs to the ArsC family
LDP97_RS10055	COG0798	PFAM Bile acid sodium symporter
LDP97_RS10060	COG0640	Transcriptional regulator
LDP97_RS10065	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDP97_RS10065	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LDP97_RS10070	COG0509	glycine decarboxylation via glycine cleavage system
LDP97_RS10075	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LDP97_RS10080	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDP97_RS10085	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LDP97_RS10105	COG2814	Major facilitator Superfamily
LDP97_RS10110	COG0625	glutathione transferase activity
LDP97_RS10120	COG0483	inositol monophosphate 1-phosphatase activity
LDP97_RS10140	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDP97_RS10155	COG1086	Polysaccharide biosynthesis protein
LDP97_RS10175	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDP97_RS10185	COG2089	acid synthase
LDP97_RS10255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDP97_RS10255	COG0301	tRNA thio-modification
LDP97_RS10265	COG4953	penicillin-binding protein 1C
LDP97_RS10270	COG2373	Large extracellular alpha-helical protein
LDP97_RS10280	COG0628	permease
LDP97_RS10285	COG1538	Outer membrane efflux protein
LDP97_RS10305	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDP97_RS10315	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LDP97_RS10335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS10345	COG2431	L-lysine efflux transmembrane transporter activity
LDP97_RS10350	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDP97_RS10355	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
LDP97_RS10370	COG1393	Belongs to the ArsC family
LDP97_RS10380	COG4783	chaperone-mediated protein folding
LDP97_RS10385	COG0425	Belongs to the sulfur carrier protein TusA family
LDP97_RS10410	COG3842	ATPase activity
LDP97_RS10415	COG3833	ABC-type maltose transport systems, permease component
LDP97_RS10420	COG1175	transmembrane transport
LDP97_RS10430	COG3081	Nucleoid-associated protein
LDP97_RS10435	COG3082	Protein of unknown function (DUF1414)
LDP97_RS10440	COG3083	sulfuric ester hydrolase activity
LDP97_RS10450	COG4771	TonB-dependent receptor
LDP97_RS10455	COG1770	oligopeptidase
LDP97_RS10475	COG4574	serine-type endopeptidase inhibitor activity
LDP97_RS10480	COG3085	chromosome segregation
LDP97_RS10485	COG0583	DNA-binding transcription factor activity
LDP97_RS10490	COG1605	Chorismate mutase
LDP97_RS10490	COG0287	Prephenate dehydrogenase
LDP97_RS10495	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
LDP97_RS10500	COG0584	glycerophosphoryl diester phosphodiesterase
LDP97_RS10515	COG1349	DNA-binding transcription factor activity
LDP97_RS10520	COG2271	Major facilitator Superfamily
LDP97_RS10525	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDP97_RS10530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
LDP97_RS10535	COG0583	DNA-binding transcription factor activity
LDP97_RS10555	COG0656	L-ascorbic acid biosynthetic process
LDP97_RS10560	COG2814	Major facilitator Superfamily
LDP97_RS10570	COG1294	oxidase, subunit
LDP97_RS10580	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP97_RS10590	COG2979	Protein of unknown function (DUF533)
LDP97_RS10615	COG2271	Major facilitator Superfamily
LDP97_RS10620	COG0583	DNA-binding transcription factor activity
LDP97_RS10630	COG2807	transmembrane transport
LDP97_RS10635	COG1187	pseudouridine synthase activity
LDP97_RS10660	COG1061	Type III restriction enzyme res subunit
LDP97_RS10670	COG2964	Protein conserved in bacteria
LDP97_RS10675	COG3681	Belongs to the UPF0597 family
LDP97_RS10685	COG0814	amino acid
LDP97_RS10705	COG1166	arginine decarboxylase activity
LDP97_RS10710	COG2195	Cleaves the N-terminal amino acid of tripeptides
LDP97_RS10740	COG0583	DNA-binding transcription factor activity
LDP97_RS10750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LDP97_RS10755	COG0840	transmembrane signaling receptor activity
LDP97_RS10760	COG0302	gtp cyclohydrolase
LDP97_RS10770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDP97_RS10775	COG2267	carboxylic ester hydrolase activity
LDP97_RS10780	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
LDP97_RS10795	COG0314	molybdopterin synthase activity
LDP97_RS10800	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
LDP97_RS10805	COG0315	cyclic pyranopterin monophosphate synthase activity
LDP97_RS10810	COG0521	Mo-molybdopterin cofactor biosynthetic process
LDP97_RS10815	COG3005	denitrification pathway
LDP97_RS10825	COG0348	domain, Protein
LDP97_RS10830	COG0437	4 iron, 4 sulfur cluster binding
LDP97_RS10835	COG0243	molybdopterin cofactor binding
LDP97_RS10845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDP97_RS10845	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDP97_RS10850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LDP97_RS10855	COG3850	Histidine kinase
LDP97_RS10860	COG2197	response regulator
LDP97_RS10890	COG0121	glutamine amidotransferase
LDP97_RS10895	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDP97_RS10900	COG1960	acyl-CoA dehydrogenase activity
LDP97_RS10905	COG3437	response regulator, receiver
LDP97_RS10905	COG0784	Response regulator, receiver
LDP97_RS10920	COG0328	RNA-DNA hybrid ribonuclease activity
LDP97_RS10925	COG2226	methyltransferase
LDP97_RS10930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LDP97_RS10935	COG0741	lytic transglycosylase activity
LDP97_RS10935	COG1388	LysM domain
LDP97_RS10940	COG3021	interspecies interaction between organisms
LDP97_RS10950	COG1607	acyl-coa hydrolase
LDP97_RS10965	COG0741	lytic transglycosylase activity
LDP97_RS10975	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
LDP97_RS11000	COG0729	surface antigen
LDP97_RS11010	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDP97_RS11015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
LDP97_RS11025	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDP97_RS11035	COG4134	Bacterial extracellular solute-binding protein
LDP97_RS11045	COG4136	ATPase activity
LDP97_RS11050	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDP97_RS11055	COG2951	lytic endotransglycosylase activity
LDP97_RS11060	COG1846	Transcriptional regulator
LDP97_RS11070	COG0033	Phosphoglucomutase
LDP97_RS11075	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
LDP97_RS11080	COG0596	Alpha beta hydrolase
LDP97_RS11095	COG0716	FMN binding
LDP97_RS11105	COG0735	belongs to the Fur family
LDP97_RS11110	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDP97_RS11120	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS11120	COG1263	PTS System
LDP97_RS11120	COG2190	(PTS) system
LDP97_RS11125	COG0363	glucosamine-6-phosphate deaminase activity
LDP97_RS11130	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDP97_RS11135	COG1940	carbohydrate kinase activity
LDP97_RS11135	COG1846	Transcriptional regulator
LDP97_RS11140	COG2194	sulfuric ester hydrolase activity
LDP97_RS11145	COG0217	transcriptional regulatory protein
LDP97_RS11150	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LDP97_RS11155	COG1801	Protein of unknown function DUF72
LDP97_RS11160	COG4106	trans-aconitate 2-methyltransferase activity
LDP97_RS11165	COG0500	methyltransferase
LDP97_RS11185	COG0450	alkyl hydroperoxide reductase
LDP97_RS11190	COG0583	DNA-binding transcription factor activity
LDP97_RS11200	COG0791	NLP P60 protein
LDP97_RS11215	COG1309	transcriptional regulator
LDP97_RS11255	COG0534	Mate efflux family protein
LDP97_RS11275	COG2366	antibiotic biosynthetic process
LDP97_RS11280	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
LDP97_RS11280	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LDP97_RS11280	COG1013	pyruvate-flavodoxin oxidoreductase activity
LDP97_RS11280	COG0674	pyruvate-flavodoxin oxidoreductase activity
LDP97_RS11290	COG3217	Mosc domain protein beta barrel domain protein
LDP97_RS11290	COG0633	Ferredoxin
LDP97_RS11290	COG3217	Mosc domain protein beta barrel domain protein
LDP97_RS11290	COG0633	Ferredoxin
LDP97_RS11300	COG0501	Belongs to the peptidase M48B family
LDP97_RS11305	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
LDP97_RS11310	COG1073	alpha beta
LDP97_RS11310	COG2226	methyltransferase
LDP97_RS11315	COG0156	8-amino-7-oxononanoate synthase activity
LDP97_RS11320	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LDP97_RS11340	COG0017	Asparaginyl-tRNA synthetase
LDP97_RS11345	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LDP97_RS11360	COG3069	C4-dicarboxylate transmembrane transporter activity
LDP97_RS11370	COG0583	DNA-binding transcription factor activity
LDP97_RS11375	COG1393	Belongs to the ArsC family
LDP97_RS11380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LDP97_RS11385	COG1876	peptidase activity
LDP97_RS11395	COG3263	regulation of cellular component size
LDP97_RS11415	COG1280	lysine exporter protein (LysE YggA)
LDP97_RS11440	COG1957	nucleoside hydrolase
LDP97_RS11445	COG0564	pseudouridine synthase activity
LDP97_RS11455	COG1454	alcohol dehydrogenase
LDP97_RS11505	COG4964	Belongs to the GSP D family
LDP97_RS11535	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDP97_RS11540	COG0702	epimerase
LDP97_RS11545	COG2914	Belongs to the UPF0125 (RnfH) family
LDP97_RS11550	COG2867	negative regulation of translational initiation
LDP97_RS11555	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LDP97_RS11640	COG4397	Mu-like prophage major head subunit gpT
LDP97_RS11645	COG4388	Caudovirus prohead serine protease
LDP97_RS11665	COG4383	Mu-like prophage protein gp29
LDP97_RS11670	COG4373	Mu-like prophage FluMu protein gp28
LDP97_RS11680	COG0640	Transcriptional regulator
LDP97_RS11720	COG5566	PFAM Mor transcription activator
LDP97_RS11830	COG0583	DNA-binding transcription factor activity
LDP97_RS11835	COG2610	gluconate transmembrane transporter activity
LDP97_RS11840	COG3048	D-serine ammonia-lyase activity
LDP97_RS11850	COG0538	isocitrate dehydrogenase activity
LDP97_RS11855	COG2207	Transcriptional regulator
LDP97_RS11875	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP97_RS11885	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
LDP97_RS11890	COG1263	PTS System
LDP97_RS11890	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS11895	COG1609	Transcriptional regulator
LDP97_RS11910	COG0456	acetyltransferase
LDP97_RS11930	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP97_RS11930	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP97_RS11930	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS11940	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
LDP97_RS11950	COG1187	pseudouridine synthase activity
LDP97_RS11960	COG0482	sulfurtransferase activity
LDP97_RS11965	COG2915	High frequency lysogenization protein hflD homolog
LDP97_RS11970	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDP97_RS11975	COG2850	peptidyl-arginine hydroxylation
LDP97_RS11985	COG3153	acetyltransferase
LDP97_RS11995	COG0625	glutathione transferase activity
LDP97_RS12000	COG0259	pyridoxamine-phosphate oxidase activity
LDP97_RS12015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDP97_RS12015	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDP97_RS12020	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LDP97_RS12035	COG3088	subunit of a heme lyase
LDP97_RS12035	COG4235	cytochrome complex assembly
LDP97_RS12040	COG3088	subunit of a heme lyase
LDP97_RS12040	COG4235	cytochrome complex assembly
LDP97_RS12045	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP97_RS12050	COG1138	Cytochrome C-type biogenesis protein
LDP97_RS12055	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LDP97_RS12060	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDP97_RS12065	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDP97_RS12070	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LDP97_RS12085	COG0835	chemotaxis
LDP97_RS12095	COG1192	Involved in chromosome partitioning
LDP97_RS12100	COG1360	Flagellar Motor Protein
LDP97_RS12105	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
LDP97_RS12110	COG2201	protein-glutamate methylesterase activity
LDP97_RS12115	COG0643	Histidine kinase
LDP97_RS12115	COG0784	Response regulator, receiver
LDP97_RS12115	COG2198	Histidine kinase
LDP97_RS12120	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
LDP97_RS12145	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
LDP97_RS12155	COG1684	flagellar biosynthetic protein fliR
LDP97_RS12210	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
LDP97_RS12220	COG1677	Flagellar hook-basal body complex protein FliE
LDP97_RS12235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LDP97_RS12245	COG1073	alpha beta
LDP97_RS12245	COG3064	Membrane
LDP97_RS12245	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
LDP97_RS12250	COG2994	toxin metabolic process
LDP97_RS12260	COG2274	protein secretion by the type I secretion system
LDP97_RS12270	COG2274	protein secretion by the type I secretion system
LDP97_RS12290	COG1737	Transcriptional regulator
LDP97_RS12295	COG0469	pyruvate kinase activity
LDP97_RS12305	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP97_RS12310	COG1960	acyl-CoA dehydrogenase activity
LDP97_RS12325	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
LDP97_RS12360	COG0243	molybdopterin cofactor binding
LDP97_RS12365	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
LDP97_RS12370	COG0583	DNA-binding transcription factor activity
LDP97_RS12405	COG1454	alcohol dehydrogenase
LDP97_RS12405	COG1012	belongs to the aldehyde dehydrogenase family
LDP97_RS12415	COG1012	belongs to the aldehyde dehydrogenase family
LDP97_RS12415	COG1454	alcohol dehydrogenase
LDP97_RS12420	COG1882	Formate acetyltransferase
LDP97_RS12425	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LDP97_RS12435	COG4869	propanediol catabolic process
LDP97_RS12475	COG4409	exo-alpha-(2->6)-sialidase activity
LDP97_RS12480	COG2731	YhcH YjgK YiaL family protein
LDP97_RS12485	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP97_RS12495	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
LDP97_RS12500	COG1737	Transcriptional regulator
LDP97_RS12505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDP97_RS12510	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
LDP97_RS12515	COG1349	DNA-binding transcription factor activity
LDP97_RS12520	COG0738	Major facilitator superfamily
LDP97_RS12530	COG1070	Carbohydrate kinase
LDP97_RS12550	COG4172	Belongs to the ABC transporter superfamily
LDP97_RS12555	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDP97_RS12565	COG0747	negative chemotaxis
LDP97_RS12580	COG1376	ErfK ybiS ycfS ynhG family protein
LDP97_RS12580	COG1388	LysM domain
LDP97_RS12595	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
LDP97_RS12600	COG0791	NLP P60 protein
LDP97_RS12605	COG2091	lysine biosynthetic process via aminoadipic acid
LDP97_RS12610	COG3118	belongs to the thioredoxin family
LDP97_RS12620	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LDP97_RS12625	COG0788	formyltetrahydrofolate deformylase activity
LDP97_RS12635	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP97_RS12655	COG0366	Alpha amylase catalytic
LDP97_RS12660	COG0739	heme binding
LDP97_RS12660	COG0741	lytic transglycosylase activity
LDP97_RS12660	COG1196	nuclear chromosome segregation
LDP97_RS12665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDP97_RS12670	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LDP97_RS12675	COG0673	inositol 2-dehydrogenase activity
LDP97_RS12700	COG1032	radical SAM domain protein
LDP97_RS12710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP97_RS12715	COG1566	PFAM secretion protein HlyD family protein
LDP97_RS12725	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDP97_RS12730	COG0733	neurotransmitter:sodium symporter activity
LDP97_RS12760	COG0281	malic enzyme
LDP97_RS12770	COG0534	Mate efflux family protein
LDP97_RS12785	COG2233	PERMEase
LDP97_RS12790	COG0095	Lipoate-protein ligase
LDP97_RS12795	COG1115	amino acid carrier protein
LDP97_RS12800	COG0019	diaminopimelate decarboxylase activity
LDP97_RS12810	COG0678	peroxiredoxin activity
LDP97_RS12820	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
LDP97_RS12840	COG1131	(ABC) transporter
LDP97_RS12845	COG0545	Peptidyl-prolyl cis-trans isomerase
LDP97_RS12850	COG3142	Participates in the control of copper homeostasis
LDP97_RS12875	COG5002	protein histidine kinase activity
LDP97_RS12880	COG0745	RESPONSE REGULATOR receiver
LDP97_RS12885	COG0346	lactoylglutathione lyase activity
LDP97_RS12890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
LDP97_RS12895	COG1960	acyl-CoA dehydrogenase activity
LDP97_RS12900	COG3284	Transcriptional regulator
LDP97_RS12915	COG0697	spore germination
LDP97_RS12920	COG4565	transcriptional regulatory protein
LDP97_RS12925	COG3290	protein histidine kinase activity
LDP97_RS12930	COG0281	malic enzyme
LDP97_RS12945	COG1846	Transcriptional regulator
LDP97_RS12950	COG1566	PFAM secretion protein HlyD family protein
LDP97_RS12980	COG0602	queuosine metabolic process
LDP97_RS12985	COG1328	CTP reductase activity
LDP97_RS12995	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LDP97_RS13000	COG3115	cell septum assembly
LDP97_RS13005	COG1196	nuclear chromosome segregation
LDP97_RS13015	COG2860	membrane
LDP97_RS13025	COG3108	Peptidase M15
LDP97_RS13030	COG2989	Protein conserved in bacteria
LDP97_RS13045	COG0463	Glycosyl transferase, family 2
LDP97_RS13060	COG0366	Alpha amylase catalytic
LDP97_RS13095	COG3706	GGDEF domain
LDP97_RS13100	COG0037	tRNA processing
LDP97_RS13105	COG3590	peptidase
LDP97_RS13115	COG0488	(ABC) transporter
LDP97_RS13125	COG0531	amino acid
LDP97_RS13140	COG0814	amino acid
LDP97_RS13155	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
LDP97_RS13160	COG1982	Orn Lys Arg decarboxylase major
LDP97_RS13165	COG0531	amino acid
LDP97_RS13170	COG3710	Transcriptional regulator
LDP97_RS13175	COG0825	malonyl-CoA metabolic process
LDP97_RS13185	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LDP97_RS13190	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LDP97_RS13195	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LDP97_RS13200	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDP97_RS13205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LDP97_RS13220	COG0750	zinc metalloprotease
LDP97_RS13225	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
LDP97_RS13230	COG0575	Belongs to the CDS family
LDP97_RS13235	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDP97_RS13240	COG0233	cytoplasmic translational termination
LDP97_RS13245	COG0528	UMP kinase activity
LDP97_RS13250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LDP97_RS13255	COG0052	Belongs to the universal ribosomal protein uS2 family
LDP97_RS13260	COG0024	Methionine aminopeptidase
LDP97_RS13265	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
LDP97_RS13270	COG2171	N-acyltransferase activity
LDP97_RS13280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS13280	COG1263	PTS System
LDP97_RS13290	COG4580	involved in the transport of maltose and maltodextrins
LDP97_RS13300	COG0564	pseudouridine synthase activity
LDP97_RS13305	COG3098	single-species biofilm formation
LDP97_RS13330	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
LDP97_RS13340	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LDP97_RS13340	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
LDP97_RS13355	COG1611	Belongs to the LOG family
LDP97_RS13360	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDP97_RS13365	COG0473	3-isopropylmalate dehydrogenase activity
LDP97_RS13375	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
LDP97_RS13380	COG2363	Small membrane protein
LDP97_RS13390	COG0583	DNA-binding transcription factor activity
LDP97_RS13395	COG0840	transmembrane signaling receptor activity
LDP97_RS13400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDP97_RS13415	COG1477	protein flavinylation
LDP97_RS13420	COG2871	sodium ion transport
LDP97_RS13425	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDP97_RS13430	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDP97_RS13435	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDP97_RS13440	COG1805	sodium ion transport
LDP97_RS13445	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
LDP97_RS13450	COG0271	Belongs to the BolA IbaG family
LDP97_RS13455	COG2813	Specifically methylates the guanine in position
LDP97_RS13465	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDP97_RS13475	COG2211	Major facilitator Superfamily
LDP97_RS13480	COG3248	Nucleoside-binding outer membrane protein
LDP97_RS13485	COG1666	GTP binding
LDP97_RS13490	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
LDP97_RS13495	COG0693	protein deglycase activity
LDP97_RS13550	COG2771	luxR family
LDP97_RS13560	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDP97_RS13560	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDP97_RS13565	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDP97_RS13575	COG1151	hydroxylamine reductase activity
LDP97_RS13580	COG0783	Belongs to the Dps family
LDP97_RS13605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LDP97_RS13620	COG4221	oxidoreductase activity
LDP97_RS13630	COG0415	Belongs to the DNA photolyase family
LDP97_RS13635	COG0789	Transcriptional regulator
LDP97_RS13640	COG3272	Protein of unknown function (DUF1722)
LDP97_RS13670	COG0077	Prephenate dehydratase
LDP97_RS13670	COG1605	Chorismate mutase
LDP97_RS13700	COG5377	YqaJ viral recombinase family
LDP97_RS13745	COG2003	Belongs to the UPF0758 family
LDP97_RS13755	COG0602	queuosine metabolic process
LDP97_RS13760	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
LDP97_RS13785	COG0720	synthase
LDP97_RS13820	COG0514	ATP-dependent DNA helicase (RecQ)
LDP97_RS13825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDP97_RS13850	COG4771	TonB-dependent receptor
LDP97_RS13870	COG1116	anion transmembrane transporter activity
LDP97_RS13895	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP97_RS13900	COG1120	ATPase activity
LDP97_RS13910	COG2226	methyltransferase
LDP97_RS13960	COG2133	pyrroloquinoline quinone binding
LDP97_RS13970	COG0840	transmembrane signaling receptor activity
LDP97_RS13980	COG0300	oxidoreductase activity
LDP97_RS14005	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
LDP97_RS14020	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
LDP97_RS14030	COG0826	peptidase U32
LDP97_RS14035	COG1280	lysine exporter protein (LysE YggA)
LDP97_RS14045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDP97_RS14050	COG0840	transmembrane signaling receptor activity
LDP97_RS14065	COG2198	Histidine kinase
LDP97_RS14065	COG0643	Histidine kinase
LDP97_RS14075	COG0835	chemotaxis
LDP97_RS14080	COG0840	transmembrane signaling receptor activity
LDP97_RS14090	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
LDP97_RS14095	COG2201	protein-glutamate methylesterase activity
LDP97_RS14100	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDP97_RS14120	COG2200	EAL domain
LDP97_RS14120	COG2203	Gaf domain
LDP97_RS14120	COG2199	diguanylate cyclase activity
LDP97_RS14125	COG0826	peptidase U32
LDP97_RS14130	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
LDP97_RS14140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDP97_RS14145	COG0305	Participates in initiation and elongation during chromosome replication
LDP97_RS14155	COG2200	EAL domain
LDP97_RS14160	COG0737	Belongs to the 5'-nucleotidase family
LDP97_RS14180	COG2204	response regulator
LDP97_RS14185	COG0545	Peptidyl-prolyl cis-trans isomerase
LDP97_RS14200	COG1047	Peptidyl-prolyl cis-trans
LDP97_RS14205	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
LDP97_RS14215	COG0784	Response regulator, receiver
LDP97_RS14215	COG0835	chemotaxis
LDP97_RS14220	COG0429	hydrolase of the alpha beta-hydrolase fold
LDP97_RS14225	COG2203	Gaf domain
LDP97_RS14225	COG3706	GGDEF domain
LDP97_RS14225	COG4251	negative regulation of phosphorylation
LDP97_RS14225	COG5001	Diguanylate cyclase
LDP97_RS14230	COG3089	Belongs to the UPF0270 family
LDP97_RS14240	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
LDP97_RS14245	COG0463	Glycosyl transferase, family 2
LDP97_RS14250	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LDP97_RS14250	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDP97_RS14255	COG0726	polysaccharide deacetylase
LDP97_RS14260	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LDP97_RS14265	COG2076	Multidrug Resistance protein
LDP97_RS14270	COG2076	Multidrug Resistance protein
LDP97_RS14275	COG3954	Phosphoribulokinase
LDP97_RS14290	COG1765	OsmC-like protein
LDP97_RS14300	COG2226	methyltransferase
LDP97_RS14305	COG3397	chitin binding
LDP97_RS14320	COG2202	Pas domain
LDP97_RS14320	COG2205	protein histidine kinase activity
LDP97_RS14330	COG3655	Transcriptional regulator
LDP97_RS14335	COG2814	Major facilitator Superfamily
LDP97_RS14340	COG4771	TonB-dependent receptor
LDP97_RS14360	COG0748	coenzyme F420 binding
LDP97_RS14365	COG3721	Heme iron utilization protein
LDP97_RS14375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LDP97_RS14400	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LDP97_RS14405	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP97_RS14410	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
LDP97_RS14430	COG0741	lytic transglycosylase activity
LDP97_RS14435	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDP97_RS14530	COG0616	signal peptide processing
LDP97_RS14545	COG1802	Transcriptional regulator
LDP97_RS14545	COG4626	Terminase
LDP97_RS14595	COG0464	growth
LDP97_RS14730	COG0582	viral genome integration into host DNA
LDP97_RS14735	COG0488	(ABC) transporter
LDP97_RS14745	COG2252	PERMEase
LDP97_RS14750	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
LDP97_RS14755	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
LDP97_RS14765	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LDP97_RS14775	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LDP97_RS14780	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LDP97_RS14785	COG2967	ApaG domain
LDP97_RS14790	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
LDP97_RS14800	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
LDP97_RS14805	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
LDP97_RS14820	COG0318	PFAM AMP-dependent synthetase and ligase
LDP97_RS14825	COG3314	Sporulation integral membrane protein YlbJ
LDP97_RS14830	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDP97_RS14835	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LDP97_RS14840	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LDP97_RS14845	COG0142	geranyltranstransferase activity
LDP97_RS14850	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
LDP97_RS14855	COG0330	HflC and HflK could
LDP97_RS14860	COG0330	HflC and HflK could
LDP97_RS14865	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDP97_RS14870	COG1923	regulation of RNA biosynthetic process
LDP97_RS14875	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LDP97_RS14880	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LDP97_RS14890	COG0802	atpase or kinase
LDP97_RS14895	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
LDP97_RS14895	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDP97_RS14915	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDP97_RS14920	COG2011	ABC-type metal ion transport system permease component
LDP97_RS14925	COG1464	Belongs to the NlpA lipoprotein family
LDP97_RS14935	COG0840	transmembrane signaling receptor activity
LDP97_RS14960	COG2198	Histidine kinase
LDP97_RS14960	COG0784	Response regulator, receiver
LDP97_RS14960	COG5002	protein histidine kinase activity
LDP97_RS14980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
LDP97_RS14995	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDP97_RS15000	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
LDP97_RS15010	COG2716	regulation of RNA biosynthetic process
LDP97_RS15015	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LDP97_RS15020	COG3013	Belongs to the UPF0304 family
LDP97_RS15030	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
LDP97_RS15035	COG0857	belongs to the CobB CobQ family
LDP97_RS15035	COG0280	phosphate acetyltransferase
LDP97_RS15045	COG0028	Belongs to the TPP enzyme family
LDP97_RS15060	COG0671	phosphoesterase, PA-phosphatase related
LDP97_RS15070	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
LDP97_RS15075	COG0473	3-isopropylmalate dehydrogenase activity
LDP97_RS15080	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
LDP97_RS15085	COG0066	3-isopropylmalate dehydratase activity
LDP97_RS15105	COG1178	ABC-type Fe3 transport system permease component
LDP97_RS15110	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LDP97_RS15115	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
LDP97_RS15125	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDP97_RS15155	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
LDP97_RS15160	COG0564	pseudouridine synthase activity
LDP97_RS15175	COG5001	Diguanylate cyclase
LDP97_RS15175	COG3300	MHYT domain
LDP97_RS15185	COG0459	protein refolding
LDP97_RS15190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LDP97_RS15195	COG0534	Mate efflux family protein
LDP97_RS15200	COG3030	protein affecting phage T7 exclusion by the F plasmid
LDP97_RS15205	COG1027	Aspartate ammonia-lyase
LDP97_RS15210	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
LDP97_RS15220	COG0477	Major facilitator Superfamily
LDP97_RS15240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDP97_RS15250	COG0673	inositol 2-dehydrogenase activity
LDP97_RS15260	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDP97_RS15265	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDP97_RS15270	COG3036	rescue of stalled ribosome
LDP97_RS15275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
LDP97_RS15285	COG0138	bifunctional purine biosynthesis protein purh
LDP97_RS15290	COG0151	Belongs to the GarS family
LDP97_RS15320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDP97_RS15325	COG0358	DNA primase activity
LDP97_RS15330	COG1610	YqeY-like protein
LDP97_RS15335	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LDP97_RS15340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LDP97_RS15355	COG1238	metal cluster binding
LDP97_RS15360	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LDP97_RS15365	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
LDP97_RS15370	COG0585	pseudouridine synthase activity
LDP97_RS15380	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LDP97_RS15385	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
LDP97_RS15390	COG0148	phosphopyruvate hydratase activity
LDP97_RS15395	COG0504	CTP synthase activity
LDP97_RS15400	COG3956	TIGRFAM MazG family protein
LDP97_RS15405	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDP97_RS15410	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDP97_RS15420	COG4807	Protein conserved in bacteria
LDP97_RS15425	COG3023	N-Acetylmuramoyl-L-alanine amidase
LDP97_RS15430	COG1349	DNA-binding transcription factor activity
LDP97_RS15440	COG2222	sugar isomerase
LDP97_RS15445	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS15455	COG3716	PTS system mannose fructose sorbose family IID component
LDP97_RS15460	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS15465	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
LDP97_RS15480	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
LDP97_RS15485	COG1381	Involved in DNA repair and RecF pathway recombination
LDP97_RS15495	COG0571	ribonuclease III activity
LDP97_RS15500	COG0681	Belongs to the peptidase S26 family
LDP97_RS15505	COG0481	GTPase activity
LDP97_RS15520	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
LDP97_RS15525	COG1595	DNA-templated transcription, initiation
LDP97_RS15530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
LDP97_RS15540	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LDP97_RS15545	COG0354	folic acid binding
LDP97_RS15580	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDP97_RS15585	COG0191	fructose-bisphosphate aldolase activity
LDP97_RS15590	COG0126	phosphoglycerate kinase activity
LDP97_RS15595	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDP97_RS15600	COG1940	carbohydrate kinase activity
LDP97_RS15605	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
LDP97_RS15620	COG4991	sh3 domain protein
LDP97_RS15625	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
LDP97_RS15640	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LDP97_RS15660	COG1505	serine-type exopeptidase activity
LDP97_RS15665	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
LDP97_RS15670	COG0765	amino acid transport
LDP97_RS15675	COG0765	amino acid transport
LDP97_RS15680	COG1126	abc transporter atp-binding protein
LDP97_RS15685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS15690	COG1136	(ABC) transporter
LDP97_RS15690	COG0577	efflux transmembrane transporter activity
LDP97_RS15695	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDP97_RS15700	COG0745	RESPONSE REGULATOR receiver
LDP97_RS15705	COG2205	protein histidine kinase activity
LDP97_RS15740	COG2070	2-Nitropropane dioxygenase
LDP97_RS15765	COG1858	cytochrome C peroxidase
LDP97_RS15770	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
LDP97_RS15790	COG0513	Belongs to the DEAD box helicase family
LDP97_RS15810	COG0154	amidase activity
LDP97_RS15815	COG2957	Belongs to the agmatine deiminase family
LDP97_RS15830	COG1902	pentaerythritol trinitrate reductase activity
LDP97_RS15875	COG0714	Associated with various cellular activities
LDP97_RS15885	COG0456	acetyltransferase
LDP97_RS15895	COG1022	Amp-dependent synthetase and ligase
LDP97_RS15905	COG2918	glutathione biosynthetic process
LDP97_RS15910	COG0612	Peptidase, M16
LDP97_RS15915	COG1238	metal cluster binding
LDP97_RS15940	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDP97_RS15945	COG0359	binds to the 23S rRNA
LDP97_RS15950	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LDP97_RS15955	COG0360	Binds together with S18 to 16S ribosomal RNA
LDP97_RS15960	COG1914	H( )-stimulated, divalent metal cation uptake system
LDP97_RS15980	COG2153	protein acetylation
LDP97_RS15990	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDP97_RS15995	COG0557	exoribonuclease II activity
LDP97_RS16000	COG3706	GGDEF domain
LDP97_RS16005	COG1854	S-ribosylhomocysteine lyase activity
LDP97_RS16020	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
LDP97_RS16020	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDP97_RS16080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LDP97_RS16085	COG1047	Peptidyl-prolyl cis-trans
LDP97_RS16090	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LDP97_RS16095	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LDP97_RS16100	COG0196	riboflavin kinase activity
LDP97_RS16110	COG0728	peptidoglycan biosynthetic process
LDP97_RS16115	COG0268	Binds directly to 16S ribosomal RNA
LDP97_RS16120	COG0640	Transcriptional regulator
LDP97_RS16125	COG0583	DNA-binding transcription factor activity
LDP97_RS16135	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LDP97_RS16140	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LDP97_RS16145	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDP97_RS16155	COG1051	belongs to the nudix hydrolase family
LDP97_RS16160	COG3066	DNA modification
LDP97_RS16170	COG0335	large ribosomal subunit rRNA binding
LDP97_RS16175	COG0336	Belongs to the RNA methyltransferase TrmD family
LDP97_RS16180	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LDP97_RS16185	COG0228	four-way junction DNA binding
LDP97_RS16190	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LDP97_RS16195	COG4137	Cytochrome C assembly protein
LDP97_RS16200	COG4536	flavin adenine dinucleotide binding
LDP97_RS16210	COG1017	nitric oxide dioxygenase activity
LDP97_RS16210	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
LDP97_RS16215	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
LDP97_RS16220	COG0039	L-malate dehydrogenase activity
LDP97_RS16225	COG4160	amino acid transport
LDP97_RS16230	COG4215	(ABC) transporter
LDP97_RS16235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS16240	COG1126	abc transporter atp-binding protein
LDP97_RS16245	COG1438	arginine binding
LDP97_RS16250	COG2837	iron assimilation
LDP97_RS16255	COG3842	ATPase activity
LDP97_RS16265	COG1840	ABC-type Fe3 transport system, periplasmic component
LDP97_RS16270	COG0347	Belongs to the P(II) protein family
LDP97_RS16285	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP97_RS16290	COG0583	DNA-binding transcription factor activity
LDP97_RS16305	COG1929	Belongs to the glycerate kinase type-1 family
LDP97_RS16310	COG2610	gluconate transmembrane transporter activity
LDP97_RS16315	COG3835	regulator
LDP97_RS16325	COG3112	Uncharacterised protein family (UPF0231)
LDP97_RS16340	COG0840	transmembrane signaling receptor activity
LDP97_RS16360	COG0513	Belongs to the DEAD box helicase family
LDP97_RS16400	COG1448	Aminotransferase
LDP97_RS16415	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
LDP97_RS16420	COG1328	CTP reductase activity
LDP97_RS16440	COG0793	Belongs to the peptidase S41A family
LDP97_RS16440	COG4946	Tricorn protease homolog
LDP97_RS16470	COG0840	transmembrane signaling receptor activity
LDP97_RS16475	COG3397	chitin binding
LDP97_RS16480	COG0583	DNA-binding transcription factor activity
LDP97_RS16485	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LDP97_RS16490	COG4208	sulfate ABC transporter
LDP97_RS16495	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
LDP97_RS16505	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
LDP97_RS16510	COG3174	membrane
LDP97_RS16515	COG0110	maltose O-acetyltransferase activity
LDP97_RS16540	COG0165	Argininosuccinate lyase
LDP97_RS16545	COG0137	argininosuccinate synthase activity
LDP97_RS16555	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDP97_RS16560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDP97_RS16570	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDP97_RS16580	COG0460	homoserine dehydrogenase
LDP97_RS16580	COG0527	aspartate kinase activity
LDP97_RS16585	COG0626	cystathionine gamma-synthase activity
LDP97_RS16595	COG2207	Transcriptional regulator
LDP97_RS16595	COG3708	Transcriptional regulator
LDP97_RS16600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDP97_RS16605	COG0814	amino acid
LDP97_RS16610	COG1218	3'(2'),5'-bisphosphate nucleotidase
LDP97_RS16615	COG0494	nUDIX hydrolase
LDP97_RS16620	COG1011	Hydrolase
LDP97_RS16625	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDP97_RS16640	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
LDP97_RS16650	COG3156	type II secretion system protein K
LDP97_RS16655	COG4795	General secretion pathway protein
LDP97_RS16660	COG2165	general secretion pathway protein
LDP97_RS16675	COG2165	general secretion pathway protein
LDP97_RS16680	COG1459	type II secretion system
LDP97_RS16685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDP97_RS16695	COG3031	protein transport across the cell outer membrane
LDP97_RS16705	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LDP97_RS16710	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
LDP97_RS16730	COG0456	acetyltransferase
LDP97_RS16735	COG3133	Outer membrane lipoprotein
LDP97_RS16750	COG2771	luxR family
LDP97_RS16755	COG3916	Acyl-homoserine-lactone synthase
LDP97_RS16765	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
LDP97_RS16770	COG1309	transcriptional regulator
LDP97_RS16780	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS16780	COG2213	PTS system mannitol-specific
LDP97_RS16785	COG0246	Mannitol dehydrogenase
LDP97_RS16790	COG3722	fumarate hydratase activity
LDP97_RS16795	COG3263	regulation of cellular component size
LDP97_RS16820	COG1671	Belongs to the UPF0178 family
LDP97_RS16835	COG1988	membrane-bound metal-dependent
LDP97_RS16840	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP97_RS16845	COG0513	Belongs to the DEAD box helicase family
LDP97_RS16870	COG1575	Belongs to the MenA family. Type 1 subfamily
LDP97_RS16875	COG1169	isochorismate synthase
LDP97_RS16880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
LDP97_RS16885	COG0596	Alpha beta hydrolase
LDP97_RS16890	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LDP97_RS16895	COG1441	menaquinone biosynthetic process
LDP97_RS16900	COG0318	PFAM AMP-dependent synthetase and ligase
LDP97_RS16915	COG3539	Fimbrial protein
LDP97_RS16920	COG3121	Chaperone
LDP97_RS16925	COG3188	usher protein
LDP97_RS16935	COG3539	Fimbrial protein
LDP97_RS16945	COG3291	Pkd domain containing protein
LDP97_RS16950	COG2949	membrane
LDP97_RS16955	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LDP97_RS16965	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
LDP97_RS16970	COG5380	lipid catabolic process
LDP97_RS16985	COG4533	DNA binding
LDP97_RS16995	COG2873	o-acetylhomoserine
LDP97_RS17005	COG1979	alcohol dehydrogenase
LDP97_RS17025	COG4221	oxidoreductase activity
LDP97_RS17045	COG1285	pathogenesis
LDP97_RS17065	COG1368	sulfuric ester hydrolase activity
LDP97_RS17070	COG1522	sequence-specific DNA binding
LDP97_RS17080	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LDP97_RS17085	COG1418	mRNA catabolic process
LDP97_RS17090	COG1058	Belongs to the CinA family
LDP97_RS17090	COG1546	Belongs to the CinA family
LDP97_RS17100	COG1129	ABC transporter
LDP97_RS17100	COG0842	Transport permease protein
LDP97_RS17115	COG0561	phosphatase activity
LDP97_RS17120	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LDP97_RS17140	COG1011	Hydrolase
LDP97_RS17155	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDP97_RS17160	COG0019	diaminopimelate decarboxylase activity
LDP97_RS17170	COG1965	Belongs to the frataxin family
LDP97_RS17175	COG0400	carboxylic ester hydrolase activity
LDP97_RS17180	COG3072	Adenylate cyclase
LDP97_RS17185	COG0181	hydroxymethylbilane synthase activity
LDP97_RS17195	COG2959	enzyme of heme biosynthesis
LDP97_RS17210	COG1494	fructose-1,6-bisphosphatase
LDP97_RS17250	COG1733	regulation of RNA biosynthetic process
LDP97_RS17270	COG3932	Exopolysaccharide synthesis, ExoD
LDP97_RS17275	COG0814	amino acid
LDP97_RS17280	COG3706	GGDEF domain
LDP97_RS17295	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
LDP97_RS17305	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
LDP97_RS17310	COG2022	thiamine diphosphate biosynthetic process
LDP97_RS17320	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
LDP97_RS17325	COG0352	thiamine-phosphate diphosphorylase activity
LDP97_RS17330	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LDP97_RS17350	COG0745	RESPONSE REGULATOR receiver
LDP97_RS17355	COG0642	Histidine kinase
LDP97_RS17365	COG0189	ligase activity
LDP97_RS17415	COG3171	Protein conserved in bacteria
LDP97_RS17435	COG3188	usher protein
LDP97_RS17475	COG1639	'signal transduction protein
LDP97_RS17485	COG2321	neutral zinc metallopeptidase
LDP97_RS17490	COG3700	Belongs to the class B bacterial acid phosphatase family
LDP97_RS17510	COG1366	Belongs to the anti-sigma-factor antagonist family
LDP97_RS17515	COG2172	sigma factor antagonist activity
LDP97_RS17520	COG0784	Response regulator, receiver
LDP97_RS17520	COG2205	protein histidine kinase activity
LDP97_RS17520	COG5002	protein histidine kinase activity
LDP97_RS17525	COG3437	response regulator, receiver
LDP97_RS17535	COG0477	Major facilitator Superfamily
LDP97_RS17550	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
LDP97_RS17555	COG1263	PTS System
LDP97_RS17555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS17575	COG0312	modulator of DNA gyrase
LDP97_RS17580	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
LDP97_RS17590	COG3164	Protein of unknown function
LDP97_RS17595	COG1530	ribonuclease E activity
LDP97_RS17600	COG0424	maF-like protein
LDP97_RS17605	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
LDP97_RS17610	COG1792	Involved in formation and maintenance of cell shape
LDP97_RS17615	COG1077	Cell shape determining protein MreB Mrl
LDP97_RS17640	COG4968	Prepilin-type N-terminal cleavage methylation domain
LDP97_RS17645	COG4969	Belongs to the N-Me-Phe pilin family
LDP97_RS17650	COG2165	general secretion pathway protein
LDP97_RS17660	COG1459	type II secretion system
LDP97_RS17665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDP97_RS17675	COG2842	Transposition protein
LDP97_RS17710	COG2199	diguanylate cyclase activity
LDP97_RS17710	COG2200	EAL domain
LDP97_RS17715	COG2200	EAL domain
LDP97_RS17720	COG0387	Pfam Sodium calcium exchanger
LDP97_RS17725	COG2986	histidine ammonia-lyase
LDP97_RS17730	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
LDP97_RS17735	COG0010	Belongs to the arginase family
LDP97_RS17740	COG1228	amidohydrolase
LDP97_RS17745	COG2188	Transcriptional regulator
LDP97_RS17750	COG0288	reversible hydration of carbon dioxide
LDP97_RS17760	COG2177	Part of the ABC transporter FtsEX involved in
LDP97_RS17765	COG2884	Cell division ATP-binding protein ftsE
LDP97_RS17770	COG0552	protein localization to endoplasmic reticulum
LDP97_RS17775	COG0742	ribosomal rna small subunit methyltransferase
LDP97_RS17800	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP97_RS17810	COG0741	lytic transglycosylase activity
LDP97_RS17820	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDP97_RS17830	COG2095	MarC family integral membrane protein
LDP97_RS17840	COG1301	dicarboxylic acid transport
LDP97_RS17865	COG3714	YhhN family
LDP97_RS17885	COG1770	oligopeptidase
LDP97_RS17900	COG4221	oxidoreductase activity
LDP97_RS17905	COG0583	DNA-binding transcription factor activity
LDP97_RS17910	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDP97_RS17955	COG0203	ribosomal protein L17
LDP97_RS17960	COG0202	RNA polymerase activity
LDP97_RS17965	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LDP97_RS17970	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LDP97_RS17975	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDP97_RS17980	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LDP97_RS17985	COG0201	protein transport
LDP97_RS17990	COG0200	Binds to the 23S rRNA
LDP97_RS17995	COG1841	ribosomal large subunit assembly
LDP97_RS18000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LDP97_RS18005	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LDP97_RS18010	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LDP97_RS18015	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LDP97_RS18020	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDP97_RS18025	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LDP97_RS18030	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LDP97_RS18035	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LDP97_RS18040	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LDP97_RS18045	COG0255	Belongs to the universal ribosomal protein uL29 family
LDP97_RS18050	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDP97_RS18055	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LDP97_RS18060	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LDP97_RS18065	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LDP97_RS18070	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDP97_RS18075	COG0089	rRNA binding
LDP97_RS18080	COG0088	Forms part of the polypeptide exit tunnel
LDP97_RS18085	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LDP97_RS18090	COG0051	transcription antitermination factor activity, RNA binding
LDP97_RS18110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDP97_RS18115	COG2183	response to ionizing radiation
LDP97_RS18135	COG0596	Alpha beta hydrolase
LDP97_RS18140	COG1040	competence protein
LDP97_RS18145	COG0316	Belongs to the HesB IscA family
LDP97_RS18145	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LDP97_RS18150	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDP97_RS18155	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LDP97_RS18160	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDP97_RS18165	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
LDP97_RS18170	COG4942	peptidase
LDP97_RS18180	COG1609	Transcriptional regulator
LDP97_RS18185	COG0800	Aldolase
LDP97_RS18190	COG0129	dihydroxy-acid dehydratase activity
LDP97_RS18195	COG3265	gluconokinase activity
LDP97_RS18200	COG2610	gluconate transmembrane transporter activity
LDP97_RS18205	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LDP97_RS18210	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LDP97_RS18220	COG0456	acetyltransferase
LDP97_RS18230	COG1490	D-aminoacyl-tRNA deacylase activity
LDP97_RS18235	COG1295	ribonuclease BN
LDP97_RS18240	COG1217	gtp-binding protein TYPA
LDP97_RS18245	COG0174	glutamine synthetase
LDP97_RS18255	COG3852	Histidine kinase
LDP97_RS18260	COG2204	response regulator
LDP97_RS18265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
LDP97_RS18270	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LDP97_RS18280	COG3078	GTPase activator activity
LDP97_RS18290	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LDP97_RS18300	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LDP97_RS18305	COG0408	coproporphyrinogen oxidase activity
LDP97_RS18310	COG0009	L-threonylcarbamoyladenylate synthase
LDP97_RS18320	COG0551	DNA topoisomerase type I activity
LDP97_RS18325	COG2922	Belongs to the Smg family
LDP97_RS18330	COG0758	DNA mediated transformation
LDP97_RS18340	COG0242	peptide deformylase activity
LDP97_RS18345	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LDP97_RS18350	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDP97_RS18350	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDP97_RS18355	COG0569	domain protein
LDP97_RS18360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDP97_RS18365	COG1322	Protein conserved in bacteria
LDP97_RS18385	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
LDP97_RS18390	COG0686	Belongs to the AlaDH PNT family
LDP97_RS18395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDP97_RS18395	COG0519	Catalyzes the synthesis of GMP from XMP
LDP97_RS18405	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
LDP97_RS18410	COG1396	sequence-specific DNA binding
LDP97_RS18415	COG1012	belongs to the aldehyde dehydrogenase family
LDP97_RS18425	COG2962	Rard protein
LDP97_RS18435	COG1280	lysine exporter protein (LysE YggA)
LDP97_RS18445	COG2391	methyltransferase activity
LDP97_RS18450	COG1280	lysine exporter protein (LysE YggA)
LDP97_RS18495	COG0583	DNA-binding transcription factor activity
LDP97_RS18500	COG1943	Transposase
LDP97_RS18515	COG0210	DNA helicase
LDP97_RS18520	COG1744	ABC transporter substrate-binding protein PnrA-like
LDP97_RS18525	COG3845	ABC transporter
LDP97_RS18530	COG4603	Belongs to the binding-protein-dependent transport system permease family
LDP97_RS18535	COG1079	Belongs to the binding-protein-dependent transport system permease family
LDP97_RS18540	COG0583	DNA-binding transcription factor activity
LDP97_RS18560	COG1262	PFAM Formylglycine-generating sulfatase enzyme
LDP97_RS18565	COG0385	Bile acid
LDP97_RS18570	COG0531	amino acid
LDP97_RS18575	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDP97_RS18580	COG0531	amino acid
LDP97_RS18585	COG2731	YhcH YjgK YiaL family protein
LDP97_RS18590	COG3250	beta-galactosidase activity
LDP97_RS18595	COG1609	Transcriptional regulator
LDP97_RS18635	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LDP97_RS18640	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDP97_RS18640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDP97_RS18645	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
LDP97_RS18650	COG3074	FtsZ-dependent cytokinesis
LDP97_RS18660	COG1045	serine acetyltransferase
LDP97_RS18670	COG0745	RESPONSE REGULATOR receiver
LDP97_RS18675	COG2205	protein histidine kinase activity
LDP97_RS18680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LDP97_RS18685	COG0534	Mate efflux family protein
LDP97_RS18700	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDP97_RS18705	COG2937	Belongs to the GPAT DAPAT family
LDP97_RS18710	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LDP97_RS18715	COG3161	chorismate lyase activity
LDP97_RS18720	COG1580	Controls the rotational direction of flagella during chemotaxis
LDP97_RS18735	COG0604	alcohol dehydrogenase
LDP97_RS18740	COG1609	Transcriptional regulator
LDP97_RS18760	COG1519	Transferase
LDP97_RS18765	COG0859	PFAM glycosyl transferase family 9
LDP97_RS18770	COG0463	Glycosyl transferase, family 2
LDP97_RS18775	COG0859	PFAM glycosyl transferase family 9
LDP97_RS18780	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDP97_RS18785	COG2990	Protein conserved in bacteria
LDP97_RS18790	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDP97_RS18800	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDP97_RS18805	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDP97_RS18810	COG2003	Belongs to the UPF0758 family
LDP97_RS18815	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDP97_RS18820	COG0756	dUTP diphosphatase activity
LDP97_RS18825	COG1309	transcriptional regulator
LDP97_RS18830	COG0668	transmembrane transport
LDP97_RS18840	COG0166	Belongs to the GPI family
LDP97_RS18850	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LDP97_RS18855	COG0583	DNA-binding transcription factor activity
LDP97_RS18895	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
LDP97_RS18900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDP97_RS18905	COG1739	Uncharacterized protein family UPF0029
LDP97_RS18910	COG0006	proline dipeptidase activity
LDP97_RS18915	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LDP97_RS18920	COG1250	3-hydroxyacyl-CoA dehydrogenase
LDP97_RS18920	COG1024	Enoyl-CoA hydratase
LDP97_RS18925	COG0183	Belongs to the thiolase family
LDP97_RS18950	COG0425	Belongs to the sulfur carrier protein TusA family
LDP97_RS18955	COG0251	oxidation-reduction process
LDP97_RS18965	COG2885	chlorophyll binding
LDP97_RS18970	COG1335	isochorismatase
LDP97_RS18975	COG2818	Glycosylase
LDP97_RS18980	COG0752	glycyl-tRNA synthetase alpha subunit
LDP97_RS18985	COG0751	glycine-tRNA ligase activity
LDP97_RS19000	COG2046	Belongs to the sulfate adenylyltransferase family
LDP97_RS19000	COG0529	Catalyzes the synthesis of activated sulfate
LDP97_RS19020	COG0814	amino acid
LDP97_RS19025	COG0348	domain, Protein
LDP97_RS19035	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDP97_RS19040	COG0426	domain, Protein
LDP97_RS19040	COG1773	rubredoxin
LDP97_RS19045	COG3604	Transcriptional regulator
LDP97_RS19050	COG2188	Transcriptional regulator
LDP97_RS19065	COG1609	Transcriptional regulator
LDP97_RS19105	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
LDP97_RS19130	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
LDP97_RS19145	COG3118	belongs to the thioredoxin family
LDP97_RS19150	COG0513	Belongs to the DEAD box helicase family
LDP97_RS19155	COG0248	Ppx GppA phosphatase
LDP97_RS19170	COG0742	ribosomal rna small subunit methyltransferase
LDP97_RS19190	COG0084	hydrolase, TatD family'
LDP97_RS19195	COG0805	protein transport
LDP97_RS19200	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LDP97_RS19210	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LDP97_RS19215	COG3165	ubiquinone biosynthetic process from chorismate
LDP97_RS19225	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDP97_RS19230	COG0402	S-adenosylhomocysteine deaminase activity
LDP97_RS19270	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
LDP97_RS19275	COG0848	biopolymer transport protein
LDP97_RS19280	COG0811	peptide transport
LDP97_RS19285	COG0811	peptide transport
LDP97_RS19295	COG2771	luxR family
LDP97_RS19300	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDP97_RS19305	COG1349	DNA-binding transcription factor activity
LDP97_RS19310	COG0745	RESPONSE REGULATOR receiver
LDP97_RS19315	COG2205	protein histidine kinase activity
LDP97_RS19325	COG4452	Inner membrane protein CreD
LDP97_RS19330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDP97_RS19335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LDP97_RS19340	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LDP97_RS19345	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LDP97_RS19350	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDP97_RS19355	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDP97_RS19360	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LDP97_RS19370	COG0356	it plays a direct role in the translocation of protons across the membrane
LDP97_RS19380	COG1475	DNA binding
LDP97_RS19385	COG1192	Involved in chromosome partitioning
LDP97_RS19390	COG0357	Ribosomal RNA small subunit methyltransferase G
LDP97_RS19395	COG0445	tRNA wobble uridine modification
LDP97_RS19400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
LDP97_RS19405	COG4774	siderophore transport
LDP97_RS19410	COG4615	Cyclic peptide transporter
LDP97_RS19415	COG1120	ATPase activity
LDP97_RS19430	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LDP97_RS19435	COG0706	membrane insertase activity
LDP97_RS19440	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LDP97_RS19445	COG0594	ribonuclease P activity
LDP97_RS19450	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LDP97_RS19455	COG1126	abc transporter atp-binding protein
LDP97_RS19470	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LDP97_RS19475	COG0592	DNA-directed DNA polymerase activity
LDP97_RS19495	COG2378	regulation of single-species biofilm formation
LDP97_RS19500	COG0071	Belongs to the small heat shock protein (HSP20) family
LDP97_RS19505	COG0071	Belongs to the small heat shock protein (HSP20) family
LDP97_RS19510	COG3977	Valine--pyruvate aminotransferase
LDP97_RS19525	COG2814	Major facilitator Superfamily
LDP97_RS19530	COG0745	RESPONSE REGULATOR receiver
LDP97_RS19535	COG2205	protein histidine kinase activity
LDP97_RS19555	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDP97_RS19560	COG4191	Histidine kinase
LDP97_RS19560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS19565	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LDP97_RS19570	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LDP97_RS19575	COG1309	transcriptional regulator
LDP97_RS19605	COG0469	pyruvate kinase activity
LDP97_RS19610	COG2271	Major facilitator Superfamily
LDP97_RS19635	COG0561	phosphatase activity
LDP97_RS19640	COG2267	carboxylic ester hydrolase activity
LDP97_RS19650	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDP97_RS19655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDP97_RS19660	COG1758	RNA polymerase activity
LDP97_RS19670	COG0859	PFAM glycosyl transferase family 9
LDP97_RS19675	COG3642	lipopolysaccharide core region biosynthetic process
LDP97_RS19715	COG0589	response to stress
LDP97_RS19720	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LDP97_RS19730	COG1528	Iron-storage protein
LDP97_RS19735	COG2081	HI0933 family
LDP97_RS19740	COG2223	nitrite transmembrane transporter activity
LDP97_RS19760	COG3188	usher protein
LDP97_RS19775	COG2197	response regulator
LDP97_RS19780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDP97_RS19780	COG2205	protein histidine kinase activity
LDP97_RS19790	COG3275	phosphorelay sensor kinase activity
LDP97_RS19795	COG3279	Response regulator of the LytR AlgR family
LDP97_RS19800	COG2223	nitrite transmembrane transporter activity
LDP97_RS19805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LDP97_RS19810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LDP97_RS19825	COG0583	DNA-binding transcription factor activity
LDP97_RS19830	COG4206	TonB-dependent receptor
LDP97_RS19835	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LDP97_RS19870	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LDP97_RS19875	COG2166	iron-sulfur cluster assembly
LDP97_RS19880	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDP97_RS19885	COG0210	DNA helicase
LDP97_RS19895	COG3245	cytochrome
LDP97_RS19900	COG1063	alcohol dehydrogenase
LDP97_RS19905	COG0156	8-amino-7-oxononanoate synthase activity
LDP97_RS19915	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
LDP97_RS19930	COG3306	glycosyltransferase involved in LPS biosynthesis
LDP97_RS19950	COG1561	YicC-like family, N-terminal region
LDP97_RS19955	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
LDP97_RS19960	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDP97_RS19970	COG0789	Transcriptional regulator
LDP97_RS19975	COG5001	Diguanylate cyclase
LDP97_RS19975	COG3706	GGDEF domain
LDP97_RS19975	COG2203	Gaf domain
LDP97_RS19975	COG4251	negative regulation of phosphorylation
LDP97_RS19980	COG3084	Protein conserved in bacteria
LDP97_RS19990	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LDP97_RS19995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LDP97_RS20000	COG3639	organic phosphonate transmembrane transporter activity
LDP97_RS20005	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
LDP97_RS20010	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
LDP97_RS20020	COG1335	isochorismatase
LDP97_RS20030	COG1683	Conserved Protein
LDP97_RS20035	COG0204	Acyl-transferase
LDP97_RS20040	COG0204	Acyl-transferase
LDP97_RS20045	COG0606	chelatase, subunit chli
LDP97_RS20055	COG3978	acetolactate synthase activity
LDP97_RS20065	COG0129	dihydroxy-acid dehydratase activity
LDP97_RS20085	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDP97_RS20090	COG0254	rRNA binding
LDP97_RS20095	COG0702	epimerase
LDP97_RS20100	COG0281	malic enzyme
LDP97_RS20110	COG2205	protein histidine kinase activity
LDP97_RS20115	COG0745	RESPONSE REGULATOR receiver
LDP97_RS20120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDP97_RS20135	COG0366	Alpha amylase catalytic
LDP97_RS20150	COG0443	Heat shock 70 kDa protein
LDP97_RS20155	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDP97_RS20160	COG3045	CreA protein
LDP97_RS20180	COG0174	glutamine synthetase
LDP97_RS20200	COG3842	ATPase activity
LDP97_RS20205	COG1176	ABC-type spermidine putrescine transport system, permease component I
LDP97_RS20210	COG1177	transmembrane transport
LDP97_RS20215	COG2258	MOSC domain
LDP97_RS20230	COG2050	protein possibly involved in aromatic compounds catabolism
LDP97_RS20235	COG0514	ATP-dependent DNA helicase (RecQ)
LDP97_RS20245	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
LDP97_RS20255	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
LDP97_RS20260	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LDP97_RS20270	COG2239	Acts as a magnesium transporter
LDP97_RS20275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDP97_RS20275	COG1648	precorrin-2 dehydrogenase activity
LDP97_RS20280	COG2116	formate transmembrane transporter activity
LDP97_RS20290	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
LDP97_RS20305	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LDP97_RS20310	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LDP97_RS20330	COG1595	DNA-templated transcription, initiation
LDP97_RS20335	COG3806	Anti-sigma factor
LDP97_RS20340	COG1968	undecaprenyl-diphosphatase activity
LDP97_RS20345	COG0667	Aldo Keto reductase
LDP97_RS20350	COG2017	converts alpha-aldose to the beta-anomer
LDP97_RS20355	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDP97_RS20365	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDP97_RS20370	COG1609	Transcriptional regulator
LDP97_RS20375	COG3250	beta-galactosidase activity
LDP97_RS20395	COG0840	transmembrane signaling receptor activity
LDP97_RS20425	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDP97_RS20430	COG1288	antiporter activity
LDP97_RS20435	COG1438	arginine binding
LDP97_RS20440	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
LDP97_RS20445	COG0540	Belongs to the ATCase OTCase family
LDP97_RS20465	COG0688	phosphatidylethanolamine metabolic process
LDP97_RS20475	COG3040	lipid binding
LDP97_RS20480	COG2207	Transcriptional regulator
LDP97_RS20485	COG1979	alcohol dehydrogenase
LDP97_RS20490	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
LDP97_RS20495	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
LDP97_RS20505	COG2964	Protein conserved in bacteria
LDP97_RS20510	COG3681	Belongs to the UPF0597 family
LDP97_RS20520	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDP97_RS20525	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LDP97_RS20530	COG0564	pseudouridine synthase activity
LDP97_RS20540	COG0542	response to heat
LDP97_RS20545	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
LDP97_RS20550	COG2502	aspartate--ammonia ligase
LDP97_RS20555	COG1522	sequence-specific DNA binding
LDP97_RS20565	COG5413	integral membrane protein
LDP97_RS20590	COG2205	protein histidine kinase activity
LDP97_RS20600	COG2204	response regulator
LDP97_RS20615	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
LDP97_RS20645	COG0243	molybdopterin cofactor binding
LDP97_RS20650	COG3005	denitrification pathway
LDP97_RS20655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDP97_RS20675	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LDP97_RS20680	COG0569	domain protein
LDP97_RS20685	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDP97_RS20710	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDP97_RS20725	COG0250	Participates in transcription elongation, termination and antitermination
LDP97_RS20730	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LDP97_RS20735	COG0081	regulation of translation
LDP97_RS20740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDP97_RS20745	COG0222	ribosome binding
LDP97_RS20750	COG0085	RNA polymerase activity
LDP97_RS20755	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LDP97_RS20765	COG2964	Protein conserved in bacteria
LDP97_RS20770	COG0251	oxidation-reduction process
LDP97_RS20780	COG2923	Belongs to the DsrF TusC family
LDP97_RS20785	COG2168	tRNA wobble position uridine thiolation
LDP97_RS20790	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LDP97_RS20795	COG0049	tRNA binding
LDP97_RS20800	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDP97_RS20805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDP97_RS20810	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
LDP97_RS20850	COG2252	PERMEase
LDP97_RS20855	COG2376	Dihydroxyacetone kinase
LDP97_RS20860	COG1461	Dihydroxyacetone kinase
LDP97_RS20875	COG3284	Transcriptional regulator
LDP97_RS20885	COG2957	Belongs to the agmatine deiminase family
LDP97_RS20890	COG4221	oxidoreductase activity
LDP97_RS20895	COG0628	permease
LDP97_RS20900	COG0494	nUDIX hydrolase
LDP97_RS20925	COG0753	catalase activity
LDP97_RS20930	COG1247	-acetyltransferase
LDP97_RS20950	COG2199	diguanylate cyclase activity
LDP97_RS20950	COG2203	Gaf domain
LDP97_RS20960	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
LDP97_RS20970	COG1175	transmembrane transport
LDP97_RS20995	COG0583	DNA-binding transcription factor activity
LDP97_RS21005	COG1741	Belongs to the pirin family
LDP97_RS21010	COG2259	Doxx family
LDP97_RS21015	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
LDP97_RS21020	COG1074	ATP-dependent DNA helicase activity
LDP97_RS21025	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDP97_RS21035	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDP97_RS21040	COG0346	lactoylglutathione lyase activity
LDP97_RS21080	COG3706	GGDEF domain
LDP97_RS21080	COG5001	Diguanylate cyclase
LDP97_RS21080	COG2203	Gaf domain
LDP97_RS21080	COG4251	negative regulation of phosphorylation
LDP97_RS21085	COG4771	TonB-dependent receptor
LDP97_RS21090	COG1278	Cold shock
LDP97_RS21110	COG0629	single-stranded DNA binding
LDP97_RS21115	COG2197	response regulator
LDP97_RS21120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDP97_RS21135	COG3047	cAMP biosynthetic process
LDP97_RS21140	COG0840	transmembrane signaling receptor activity
LDP97_RS21165	COG3135	benzoate transporter
LDP97_RS21170	COG1396	sequence-specific DNA binding
LDP97_RS21205	COG2926	Belongs to the UPF0265 family
LDP97_RS21215	COG3028	Belongs to the UPF0307 family
LDP97_RS21220	COG0312	modulator of DNA gyrase
LDP97_RS21225	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDP97_RS21230	COG5007	Belongs to the BolA IbaG family
LDP97_RS21240	COG2854	intermembrane phospholipid transfer
LDP97_RS21245	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LDP97_RS21250	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
LDP97_RS21255	COG1127	ABC transporter
LDP97_RS21260	COG0517	IMP dehydrogenase activity
LDP97_RS21260	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDP97_RS21265	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
LDP97_RS21270	COG3117	lipopolysaccharide transmembrane transporter activity
LDP97_RS21275	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
LDP97_RS21280	COG1137	ATPase activity
LDP97_RS21285	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
LDP97_RS21295	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS21300	COG1660	Displays ATPase and GTPase activities
LDP97_RS21305	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS21310	COG3711	transcriptional antiterminator
LDP97_RS21310	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LDP97_RS21325	COG3964	amidohydrolase
LDP97_RS21355	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDP97_RS21360	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDP97_RS21370	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LDP97_RS21375	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LDP97_RS21380	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDP97_RS21385	COG0723	plastoquinol--plastocyanin reductase activity
LDP97_RS21390	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LDP97_RS21395	COG2857	Cytochrome c1
LDP97_RS21400	COG0625	glutathione transferase activity
LDP97_RS21405	COG2969	positive regulation of protein catabolic process
LDP97_RS21410	COG2823	Periplasmic or secreted lipoprotein
LDP97_RS21415	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
LDP97_RS21420	COG0792	nuclease activity
LDP97_RS21425	COG3107	peptidoglycan biosynthetic process
LDP97_RS21430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LDP97_RS21440	COG2001	Belongs to the MraZ family
LDP97_RS21445	COG0275	rRNA processing
LDP97_RS21450	COG3116	cell division
LDP97_RS21455	COG0768	penicillin binding
LDP97_RS21465	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDP97_RS21470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDP97_RS21475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LDP97_RS21480	COG0772	Belongs to the SEDS family
LDP97_RS21485	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDP97_RS21490	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDP97_RS21495	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LDP97_RS21500	COG0849	cell division
LDP97_RS21505	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
LDP97_RS21510	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
LDP97_RS21520	COG0653	protein targeting
LDP97_RS21530	COG0494	nUDIX hydrolase
LDP97_RS21535	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LDP97_RS21540	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
LDP97_RS21555	COG1459	type II secretion system
LDP97_RS21560	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDP97_RS21585	COG2186	Transcriptional regulator
LDP97_RS21590	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
LDP97_RS21595	COG0508	dehydrogenase complex catalyzes the overall conversion of
LDP97_RS21600	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDP97_RS21605	COG3447	MASE1 domain protein
LDP97_RS21605	COG5002	protein histidine kinase activity
LDP97_RS21605	COG5001	Diguanylate cyclase
LDP97_RS21615	COG0840	transmembrane signaling receptor activity
LDP97_RS21620	COG0840	transmembrane signaling receptor activity
LDP97_RS21625	COG1752	Esterase of the alpha-beta hydrolase superfamily
LDP97_RS21630	COG1049	propionate catabolic process, 2-methylcitrate cycle
LDP97_RS21645	COG1280	lysine exporter protein (LysE YggA)
LDP97_RS21655	COG0523	cobalamin synthesis protein
LDP97_RS21660	COG0477	Major facilitator Superfamily
LDP97_RS21675	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
LDP97_RS21680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LDP97_RS21720	COG3314	Sporulation integral membrane protein YlbJ
LDP97_RS21725	COG0784	Response regulator, receiver
LDP97_RS21725	COG0835	chemotaxis
LDP97_RS21730	COG1028	Short-chain dehydrogenase reductase Sdr
LDP97_RS21735	COG1444	tRNA N-acetyltransferase activity
LDP97_RS21760	COG1803	Methylglyoxal synthase
LDP97_RS21775	COG0252	asparaginase activity
LDP97_RS21795	COG1263	PTS System
LDP97_RS21795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LDP97_RS21800	COG0366	Alpha amylase catalytic
LDP97_RS21805	COG0110	maltose O-acetyltransferase activity
LDP97_RS21810	COG1522	sequence-specific DNA binding
LDP97_RS21815	COG5006	permease, DMT superfamily
LDP97_RS21825	COG1012	belongs to the aldehyde dehydrogenase family
LDP97_RS21830	COG1177	transmembrane transport
LDP97_RS21835	COG1176	ABC-type spermidine putrescine transport system, permease component I
LDP97_RS21840	COG3842	ATPase activity
LDP97_RS21845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
LDP97_RS21850	COG0583	DNA-binding transcription factor activity
LDP97_RS21855	COG1757	Na H antiporter
LDP97_RS21875	COG0297	glycogen (starch) synthase activity
LDP97_RS21880	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
LDP97_RS21885	COG2813	Specifically methylates the guanine in position
LDP97_RS21890	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDP97_RS21895	COG2203	Gaf domain
LDP97_RS21895	COG4251	negative regulation of phosphorylation
LDP97_RS21895	COG5001	Diguanylate cyclase
LDP97_RS21895	COG3706	GGDEF domain
LDP97_RS21905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDP97_RS21915	COG2995	paraquat-inducible protein a
LDP97_RS21920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
LDP97_RS21920	COG3008	intermembrane lipid transfer
LDP97_RS21925	COG3009	Protein conserved in bacteria
LDP97_RS21940	COG3240	lipase activity
LDP97_RS21945	COG3111	PFAM Bacterial OB fold (BOF) protein
LDP97_RS21955	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
LDP97_RS21960	COG1194	a g-specific adenine glycosylase
LDP97_RS21970	COG3409	Peptidoglycan-binding domain 1 protein
LDP97_RS21970	COG3267	Type II secretory pathway component ExeA
LDP97_RS21975	COG0617	tRNA 3'-terminal CCA addition
LDP97_RS21990	COG1346	cytolysis
LDP97_RS21995	COG1380	Effector of murein hydrolase LrgA
LDP97_RS22000	COG0583	DNA-binding transcription factor activity
LDP97_RS22025	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LDP97_RS22030	COG0306	phosphate transporter
LDP97_RS22035	COG1392	Phosphate transport regulator
LDP97_RS22050	COG1560	Kdo2-lipid A biosynthetic process
LDP97_RS22055	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDP97_RS22055	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
LDP97_RS22060	COG1538	Outer membrane efflux protein
LDP97_RS22065	COG0494	nUDIX hydrolase
LDP97_RS22070	COG3151	Protein conserved in bacteria
LDP97_RS22080	COG3150	esterase
LDP97_RS22085	COG1051	belongs to the nudix hydrolase family
LDP97_RS22100	COG1566	PFAM secretion protein HlyD family protein
LDP97_RS22105	COG1289	transmembrane transporter activity
LDP97_RS22155	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDP97_RS22180	COG0204	Acyl-transferase
LDP97_RS22185	COG1842	Phage shock protein A
LDP97_RS22200	COG2827	Endonuclease containing a URI domain
LDP97_RS22210	COG2962	Rard protein
LDP97_RS22215	COG1573	uracil-dna glycosylase
LDP97_RS22220	COG0697	spore germination
LDP97_RS22230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDP97_RS22235	COG1121	(ABC) transporter
LDP97_RS22240	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
LDP97_RS22260	COG0739	heme binding
LDP97_RS22270	COG3068	Protein conserved in bacteria
LDP97_RS22290	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LDP97_RS22295	COG0582	viral genome integration into host DNA
LDP97_RS22325	COG1546	Belongs to the CinA family
LDP97_RS22330	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDP97_RS22340	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDP97_RS22345	COG0527	aspartate kinase activity
LDP97_RS22350	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
LDP97_RS22390	COG1686	Belongs to the peptidase S11 family
LDP97_RS22395	COG0586	Pfam SNARE associated Golgi protein
LDP97_RS22400	COG1253	flavin adenine dinucleotide binding
LDP97_RS22405	COG0525	valine-tRNA ligase activity
LDP97_RS22410	COG2927	DNA polymerase III (CHI subunit)
LDP97_RS22415	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LDP97_RS22420	COG0795	lipopolysaccharide-transporting ATPase activity
LDP97_RS22425	COG0795	lipopolysaccharide-transporting ATPase activity
LDP97_RS22440	COG0582	viral genome integration into host DNA
LDP97_RS22455	COG3561	AntA/AntB antirepressor
LDP97_RS22490	COG0004	ammonium transporteR
LDP97_RS22495	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDP97_RS22505	COG2165	general secretion pathway protein
LDP97_RS22510	COG0084	hydrolase, TatD family'
LDP97_RS22515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDP97_RS22525	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
LDP97_RS22530	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
LDP97_RS22535	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LDP97_RS22540	COG0813	purine-nucleoside phosphorylase activity
LDP97_RS22545	COG5002	protein histidine kinase activity
LDP97_RS22545	COG5001	Diguanylate cyclase
LDP97_RS22545	COG3447	MASE1 domain protein
LDP97_RS22555	COG0560	Phosphoserine phosphatase
LDP97_RS22580	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
LDP97_RS22585	COG0776	regulation of translation
LDP97_RS22600	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDP97_RS22605	COG0735	belongs to the Fur family
LDP97_RS22630	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LDP97_RS22635	COG0513	Belongs to the DEAD box helicase family
LDP97_RS22640	COG3022	response to hydroperoxide
LDP97_RS22655	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
LDP97_RS22660	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDP97_RS22665	COG0762	integral membrane protein
LDP97_RS22670	COG1872	DUF167
LDP97_RS22685	COG4166	transmembrane transport
LDP97_RS22695	COG0110	maltose O-acetyltransferase activity
LDP97_RS22705	COG1024	Enoyl-CoA hydratase
LDP97_RS22720	COG4221	oxidoreductase activity
LDP97_RS22725	COG0442	prolyl-tRNA aminoacylation
LDP97_RS22730	COG0840	transmembrane signaling receptor activity
LDP97_RS22735	COG0632	four-way junction helicase activity
LDP97_RS22740	COG2255	four-way junction helicase activity
LDP97_RS22745	COG1271	oxidase subunit
LDP97_RS22750	COG1294	oxidase, subunit
LDP97_RS22755	COG4890	Cyd operon protein YbgT
LDP97_RS22760	COG3790	cyd operon protein YbgE
LDP97_RS22765	COG0824	Thioesterase
LDP97_RS22770	COG0811	peptide transport
LDP97_RS22785	COG0823	Involved in the tonB-independent uptake of proteins
LDP97_RS22790	COG2885	chlorophyll binding
LDP97_RS22795	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
LDP97_RS22870	COG0840	transmembrane signaling receptor activity
LDP97_RS22875	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
LDP97_RS22880	COG0676	glucose-6-phosphate 1-epimerase activity
LDP97_RS22885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
LDP97_RS22890	COG1640	4-alpha-glucanotransferase
LDP97_RS22895	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
LDP97_RS22915	COG1051	belongs to the nudix hydrolase family
LDP97_RS22920	COG2130	NADP-dependent
LDP97_RS22925	COG1764	response to oxidative stress
LDP97_RS22930	COG1846	Transcriptional regulator
LDP97_RS22965	COG0561	phosphatase activity
LDP97_RS22980	COG0733	neurotransmitter:sodium symporter activity
LDP97_RS22990	COG0733	neurotransmitter:sodium symporter activity
LDP97_RS23015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDP97_RS23030	COG1794	racemase activity, acting on amino acids and derivatives
LDP97_RS23045	COG2731	YhcH YjgK YiaL family protein
LDP97_RS23055	COG0668	transmembrane transport
LDP97_RS23065	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
LDP97_RS23115	COG0583	DNA-binding transcription factor activity
LDP97_RS23120	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LDP97_RS23130	COG0488	(ABC) transporter
LDP97_RS23135	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LDP97_RS23135	COG0517	IMP dehydrogenase activity
LDP97_RS23140	COG1585	Membrane protein implicated in regulation of membrane protease activity
LDP97_RS23145	COG0330	HflC and HflK could
LDP97_RS23150	COG1648	precorrin-2 dehydrogenase activity
LDP97_RS23150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
LDP97_RS23155	COG0175	sulfate reduction
LDP97_RS23160	COG2895	sulfate adenylyltransferase (ATP) activity
LDP97_RS23165	COG0471	metal ion transport
LDP97_RS23165	COG3273	potassium ion transport
LDP97_RS23170	COG0529	Catalyzes the synthesis of activated sulfate
LDP97_RS23195	COG0840	transmembrane signaling receptor activity
LDP97_RS23215	COG1136	(ABC) transporter
LDP97_RS23230	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
LDP97_RS23245	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LDP97_RS23250	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDP97_RS23255	COG0163	prenyltransferase activity
LDP97_RS23270	COG1131	(ABC) transporter
LDP97_RS23275	COG0842	Transport permease protein
LDP97_RS23280	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
LDP97_RS23285	COG1924	4 iron, 4 sulfur cluster binding
LDP97_RS23305	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LDP97_RS23310	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LDP97_RS23325	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDP97_RS23330	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
LDP97_RS23335	COG1489	DNA binding
LDP97_RS23345	COG1643	Atp-dependent helicase
LDP97_RS23350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDP97_RS23355	COG0346	lactoylglutathione lyase activity
LDP97_RS23365	COG2076	Multidrug Resistance protein
LDP97_RS23375	COG3437	response regulator, receiver
LDP97_RS23375	COG0784	Response regulator, receiver
LDP97_RS23385	COG0671	phosphoesterase, PA-phosphatase related
LDP97_RS23400	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
LDP97_RS23405	COG0038	chloride channel
LDP97_RS23415	COG0316	Belongs to the HesB IscA family
LDP97_RS23440	COG1280	lysine exporter protein (LysE YggA)
LDP97_RS23455	COG3311	Transcriptional regulator
LDP97_RS23515	COG2003	Belongs to the UPF0758 family
LDP97_RS23570	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
LDP97_RS23590	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDP97_RS23600	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
LDP97_RS23615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family