locus-tag	class	description
BOQ57_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BOQ57_RS00020	COG1126	abc transporter atp-binding protein
BOQ57_RS00025	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BOQ57_RS00030	COG0594	ribonuclease P activity
BOQ57_RS00035	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BOQ57_RS00040	COG0706	membrane insertase activity
BOQ57_RS00045	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BOQ57_RS00060	COG1120	ATPase activity
BOQ57_RS00065	COG4615	Cyclic peptide transporter
BOQ57_RS00070	COG4774	siderophore transport
BOQ57_RS00075	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BOQ57_RS00080	COG0445	tRNA wobble uridine modification
BOQ57_RS00085	COG0357	Ribosomal RNA small subunit methyltransferase G
BOQ57_RS00090	COG1192	Involved in chromosome partitioning
BOQ57_RS00095	COG1475	DNA binding
BOQ57_RS00105	COG0356	it plays a direct role in the translocation of protons across the membrane
BOQ57_RS00115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BOQ57_RS00120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BOQ57_RS00125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BOQ57_RS00130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BOQ57_RS00135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BOQ57_RS00140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BOQ57_RS00145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BOQ57_RS00150	COG4452	Inner membrane protein CreD
BOQ57_RS00160	COG2205	protein histidine kinase activity
BOQ57_RS00165	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS00170	COG1349	DNA-binding transcription factor activity
BOQ57_RS00175	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BOQ57_RS00180	COG2771	luxR family
BOQ57_RS00190	COG0811	peptide transport
BOQ57_RS00195	COG0811	peptide transport
BOQ57_RS00200	COG0848	biopolymer transport protein
BOQ57_RS00205	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BOQ57_RS00250	COG0402	S-adenosylhomocysteine deaminase activity
BOQ57_RS00255	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BOQ57_RS00265	COG3165	ubiquinone biosynthetic process from chorismate
BOQ57_RS00270	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BOQ57_RS00280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BOQ57_RS00285	COG0805	protein transport
BOQ57_RS00290	COG0084	hydrolase, TatD family'
BOQ57_RS00310	COG0742	ribosomal rna small subunit methyltransferase
BOQ57_RS00320	COG0248	Ppx GppA phosphatase
BOQ57_RS00325	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS00330	COG3118	belongs to the thioredoxin family
BOQ57_RS00345	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BOQ57_RS00370	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BOQ57_RS00410	COG1609	Transcriptional regulator
BOQ57_RS00425	COG2188	Transcriptional regulator
BOQ57_RS00430	COG3604	Transcriptional regulator
BOQ57_RS00435	COG1773	rubredoxin
BOQ57_RS00435	COG0426	domain, Protein
BOQ57_RS00440	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOQ57_RS00450	COG0348	domain, Protein
BOQ57_RS00455	COG0814	amino acid
BOQ57_RS00475	COG0583	DNA-binding transcription factor activity
BOQ57_RS00485	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BOQ57_RS00495	COG0751	glycine-tRNA ligase activity
BOQ57_RS00500	COG0752	glycyl-tRNA synthetase alpha subunit
BOQ57_RS00505	COG2818	Glycosylase
BOQ57_RS00515	COG2885	chlorophyll binding
BOQ57_RS00520	COG0251	oxidation-reduction process
BOQ57_RS00525	COG0425	Belongs to the sulfur carrier protein TusA family
BOQ57_RS00550	COG0183	Belongs to the thiolase family
BOQ57_RS00555	COG1024	Enoyl-CoA hydratase
BOQ57_RS00555	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOQ57_RS00560	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOQ57_RS00565	COG0006	proline dipeptidase activity
BOQ57_RS00570	COG1739	Uncharacterized protein family UPF0029
BOQ57_RS00575	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BOQ57_RS00580	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BOQ57_RS00625	COG0583	DNA-binding transcription factor activity
BOQ57_RS00650	COG0668	transmembrane transport
BOQ57_RS00655	COG1309	transcriptional regulator
BOQ57_RS00660	COG0756	dUTP diphosphatase activity
BOQ57_RS00665	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BOQ57_RS00670	COG2003	Belongs to the UPF0758 family
BOQ57_RS00675	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BOQ57_RS00680	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BOQ57_RS00690	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BOQ57_RS00695	COG2990	Protein conserved in bacteria
BOQ57_RS00700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BOQ57_RS00705	COG0859	PFAM glycosyl transferase family 9
BOQ57_RS00710	COG0463	Glycosyl transferase, family 2
BOQ57_RS00715	COG0859	PFAM glycosyl transferase family 9
BOQ57_RS00720	COG1519	Transferase
BOQ57_RS00740	COG1609	Transcriptional regulator
BOQ57_RS00745	COG0604	alcohol dehydrogenase
BOQ57_RS00765	COG1580	Controls the rotational direction of flagella during chemotaxis
BOQ57_RS00770	COG3161	chorismate lyase activity
BOQ57_RS00775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BOQ57_RS00780	COG2937	Belongs to the GPAT DAPAT family
BOQ57_RS00785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BOQ57_RS00805	COG0534	Mate efflux family protein
BOQ57_RS00810	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BOQ57_RS00815	COG2205	protein histidine kinase activity
BOQ57_RS00820	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS00830	COG1045	serine acetyltransferase
BOQ57_RS00845	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BOQ57_RS00855	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BOQ57_RS00855	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BOQ57_RS00860	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BOQ57_RS00900	COG1609	Transcriptional regulator
BOQ57_RS00905	COG3250	beta-galactosidase activity
BOQ57_RS00910	COG2731	YhcH YjgK YiaL family protein
BOQ57_RS00915	COG0531	amino acid
BOQ57_RS00920	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOQ57_RS00925	COG0531	amino acid
BOQ57_RS00930	COG0385	Bile acid
BOQ57_RS00935	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BOQ57_RS00955	COG0583	DNA-binding transcription factor activity
BOQ57_RS00960	COG1079	Belongs to the binding-protein-dependent transport system permease family
BOQ57_RS00965	COG4603	Belongs to the binding-protein-dependent transport system permease family
BOQ57_RS00970	COG3845	ABC transporter
BOQ57_RS00975	COG1744	ABC transporter substrate-binding protein PnrA-like
BOQ57_RS00990	COG0210	DNA helicase
BOQ57_RS01015	COG0583	DNA-binding transcription factor activity
BOQ57_RS01070	COG1280	lysine exporter protein (LysE YggA)
BOQ57_RS01075	COG2391	methyltransferase activity
BOQ57_RS01080	COG0840	transmembrane signaling receptor activity
BOQ57_RS01090	COG1280	lysine exporter protein (LysE YggA)
BOQ57_RS01100	COG2962	Rard protein
BOQ57_RS01110	COG1012	belongs to the aldehyde dehydrogenase family
BOQ57_RS01115	COG1396	sequence-specific DNA binding
BOQ57_RS01120	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BOQ57_RS01130	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BOQ57_RS01130	COG0519	Catalyzes the synthesis of GMP from XMP
BOQ57_RS01135	COG0686	Belongs to the AlaDH PNT family
BOQ57_RS01140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOQ57_RS01160	COG1322	Protein conserved in bacteria
BOQ57_RS01165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BOQ57_RS01170	COG0569	domain protein
BOQ57_RS01175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BOQ57_RS01175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BOQ57_RS01180	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BOQ57_RS01185	COG0242	peptide deformylase activity
BOQ57_RS01195	COG0758	DNA mediated transformation
BOQ57_RS01200	COG2922	Belongs to the Smg family
BOQ57_RS01205	COG0551	DNA topoisomerase type I activity
BOQ57_RS01215	COG0009	L-threonylcarbamoyladenylate synthase
BOQ57_RS01220	COG0408	coproporphyrinogen oxidase activity
BOQ57_RS01225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BOQ57_RS01235	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BOQ57_RS01250	COG3078	GTPase activator activity
BOQ57_RS01260	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BOQ57_RS01265	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BOQ57_RS01270	COG2204	response regulator
BOQ57_RS01275	COG3852	Histidine kinase
BOQ57_RS01285	COG0174	glutamine synthetase
BOQ57_RS01290	COG1217	gtp-binding protein TYPA
BOQ57_RS01295	COG1295	ribonuclease BN
BOQ57_RS01300	COG1295	ribonuclease BN
BOQ57_RS01305	COG1490	D-aminoacyl-tRNA deacylase activity
BOQ57_RS01315	COG0456	acetyltransferase
BOQ57_RS01325	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BOQ57_RS01330	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOQ57_RS01335	COG2610	gluconate transmembrane transporter activity
BOQ57_RS01340	COG3265	gluconokinase activity
BOQ57_RS01345	COG0129	dihydroxy-acid dehydratase activity
BOQ57_RS01350	COG0800	Aldolase
BOQ57_RS01355	COG1609	Transcriptional regulator
BOQ57_RS01365	COG4942	peptidase
BOQ57_RS01370	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BOQ57_RS01375	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BOQ57_RS01380	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BOQ57_RS01385	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BOQ57_RS01390	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BOQ57_RS01390	COG0316	Belongs to the HesB IscA family
BOQ57_RS01395	COG1040	competence protein
BOQ57_RS01400	COG0596	Alpha beta hydrolase
BOQ57_RS01420	COG2183	response to ionizing radiation
BOQ57_RS01425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BOQ57_RS01445	COG0051	transcription antitermination factor activity, RNA binding
BOQ57_RS01450	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BOQ57_RS01455	COG0088	Forms part of the polypeptide exit tunnel
BOQ57_RS01460	COG0089	rRNA binding
BOQ57_RS01465	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BOQ57_RS01470	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BOQ57_RS01475	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BOQ57_RS01480	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BOQ57_RS01485	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BOQ57_RS01490	COG0255	Belongs to the universal ribosomal protein uL29 family
BOQ57_RS01495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BOQ57_RS01500	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BOQ57_RS01505	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BOQ57_RS01510	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BOQ57_RS01515	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BOQ57_RS01520	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BOQ57_RS01525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BOQ57_RS01530	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BOQ57_RS01535	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BOQ57_RS01540	COG1841	ribosomal large subunit assembly
BOQ57_RS01545	COG0200	Binds to the 23S rRNA
BOQ57_RS01550	COG0201	protein transport
BOQ57_RS01555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BOQ57_RS01560	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BOQ57_RS01565	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BOQ57_RS01570	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BOQ57_RS01575	COG0202	RNA polymerase activity
BOQ57_RS01580	COG0203	ribosomal protein L17
BOQ57_RS01640	COG2249	NAD(P)H dehydrogenase (quinone) activity
BOQ57_RS01645	COG0583	DNA-binding transcription factor activity
BOQ57_RS01650	COG4221	oxidoreductase activity
BOQ57_RS01665	COG1770	oligopeptidase
BOQ57_RS01690	COG3714	YhhN family
BOQ57_RS01715	COG1301	dicarboxylic acid transport
BOQ57_RS01725	COG2095	MarC family integral membrane protein
BOQ57_RS01735	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BOQ57_RS01745	COG0741	lytic transglycosylase activity
BOQ57_RS01750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOQ57_RS01775	COG0742	ribosomal rna small subunit methyltransferase
BOQ57_RS01780	COG0552	protein localization to endoplasmic reticulum
BOQ57_RS01785	COG2884	Cell division ATP-binding protein ftsE
BOQ57_RS01790	COG2177	Part of the ABC transporter FtsEX involved in
BOQ57_RS01800	COG0288	reversible hydration of carbon dioxide
BOQ57_RS01805	COG2188	Transcriptional regulator
BOQ57_RS01810	COG1228	amidohydrolase
BOQ57_RS01815	COG0010	Belongs to the arginase family
BOQ57_RS01820	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BOQ57_RS01825	COG2986	histidine ammonia-lyase
BOQ57_RS01830	COG0387	Pfam Sodium calcium exchanger
BOQ57_RS01835	COG2200	EAL domain
BOQ57_RS01840	COG2199	diguanylate cyclase activity
BOQ57_RS01840	COG2200	EAL domain
BOQ57_RS01885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BOQ57_RS01890	COG1459	type II secretion system
BOQ57_RS01900	COG2165	general secretion pathway protein
BOQ57_RS01935	COG1077	Cell shape determining protein MreB Mrl
BOQ57_RS01940	COG1792	Involved in formation and maintenance of cell shape
BOQ57_RS01945	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BOQ57_RS01950	COG0424	maF-like protein
BOQ57_RS01955	COG1530	ribonuclease E activity
BOQ57_RS01960	COG3164	Protein of unknown function
BOQ57_RS01970	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BOQ57_RS01975	COG0312	modulator of DNA gyrase
BOQ57_RS01995	COG1263	PTS System
BOQ57_RS01995	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS02000	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BOQ57_RS02015	COG0477	Major facilitator Superfamily
BOQ57_RS02025	COG3437	response regulator, receiver
BOQ57_RS02030	COG2205	protein histidine kinase activity
BOQ57_RS02030	COG0784	Response regulator, receiver
BOQ57_RS02030	COG5002	protein histidine kinase activity
BOQ57_RS02035	COG2172	sigma factor antagonist activity
BOQ57_RS02060	COG3700	Belongs to the class B bacterial acid phosphatase family
BOQ57_RS02065	COG2321	neutral zinc metallopeptidase
BOQ57_RS02075	COG1639	'signal transduction protein
BOQ57_RS02100	COG0189	ligase activity
BOQ57_RS02110	COG0642	Histidine kinase
BOQ57_RS02140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BOQ57_RS02145	COG0352	thiamine-phosphate diphosphorylase activity
BOQ57_RS02150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BOQ57_RS02160	COG2022	thiamine diphosphate biosynthetic process
BOQ57_RS02165	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BOQ57_RS02175	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BOQ57_RS02195	COG3706	GGDEF domain
BOQ57_RS02200	COG0814	amino acid
BOQ57_RS02205	COG3932	Exopolysaccharide synthesis, ExoD
BOQ57_RS02225	COG1733	regulation of RNA biosynthetic process
BOQ57_RS02265	COG1494	fructose-1,6-bisphosphatase
BOQ57_RS02280	COG2959	enzyme of heme biosynthesis
BOQ57_RS02290	COG0181	hydroxymethylbilane synthase activity
BOQ57_RS02295	COG3072	Adenylate cyclase
BOQ57_RS02300	COG0400	carboxylic ester hydrolase activity
BOQ57_RS02305	COG1965	Belongs to the frataxin family
BOQ57_RS02315	COG0019	diaminopimelate decarboxylase activity
BOQ57_RS02320	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BOQ57_RS02335	COG1011	Hydrolase
BOQ57_RS02355	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BOQ57_RS02360	COG0561	phosphatase activity
BOQ57_RS02375	COG0842	Transport permease protein
BOQ57_RS02375	COG1129	ABC transporter
BOQ57_RS02385	COG1058	Belongs to the CinA family
BOQ57_RS02385	COG1546	Belongs to the CinA family
BOQ57_RS02390	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BOQ57_RS02395	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BOQ57_RS02405	COG1522	sequence-specific DNA binding
BOQ57_RS02410	COG1368	sulfuric ester hydrolase activity
BOQ57_RS02430	COG1285	pathogenesis
BOQ57_RS02450	COG4221	oxidoreductase activity
BOQ57_RS02470	COG1979	alcohol dehydrogenase
BOQ57_RS02480	COG2873	o-acetylhomoserine
BOQ57_RS02490	COG4533	DNA binding
BOQ57_RS02505	COG5380	lipid catabolic process
BOQ57_RS02510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BOQ57_RS02520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BOQ57_RS02525	COG2949	membrane
BOQ57_RS02530	COG3291	Pkd domain containing protein
BOQ57_RS02540	COG3539	Fimbrial protein
BOQ57_RS02550	COG3188	usher protein
BOQ57_RS02555	COG3121	Chaperone
BOQ57_RS02560	COG3539	Fimbrial protein
BOQ57_RS02575	COG0318	PFAM AMP-dependent synthetase and ligase
BOQ57_RS02580	COG1441	menaquinone biosynthetic process
BOQ57_RS02585	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BOQ57_RS02590	COG0596	Alpha beta hydrolase
BOQ57_RS02595	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BOQ57_RS02600	COG1169	isochorismate synthase
BOQ57_RS02605	COG1575	Belongs to the MenA family. Type 1 subfamily
BOQ57_RS02630	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS02635	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BOQ57_RS02640	COG1988	membrane-bound metal-dependent
BOQ57_RS02655	COG1671	Belongs to the UPF0178 family
BOQ57_RS02680	COG3263	regulation of cellular component size
BOQ57_RS02685	COG3722	fumarate hydratase activity
BOQ57_RS02690	COG0246	Mannitol dehydrogenase
BOQ57_RS02695	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS02695	COG2213	PTS system mannitol-specific
BOQ57_RS02705	COG1309	transcriptional regulator
BOQ57_RS02710	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BOQ57_RS02720	COG3916	Acyl-homoserine-lactone synthase
BOQ57_RS02725	COG2771	luxR family
BOQ57_RS02740	COG3133	Outer membrane lipoprotein
BOQ57_RS02745	COG0456	acetyltransferase
BOQ57_RS02765	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BOQ57_RS02770	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BOQ57_RS02780	COG3031	protein transport across the cell outer membrane
BOQ57_RS02790	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BOQ57_RS02795	COG1459	type II secretion system
BOQ57_RS02800	COG2165	general secretion pathway protein
BOQ57_RS02810	COG2165	general secretion pathway protein
BOQ57_RS02815	COG4795	General secretion pathway protein
BOQ57_RS02820	COG3156	type II secretion system protein K
BOQ57_RS02830	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BOQ57_RS02845	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BOQ57_RS02850	COG1011	Hydrolase
BOQ57_RS02855	COG0494	nUDIX hydrolase
BOQ57_RS02860	COG1218	3'(2'),5'-bisphosphate nucleotidase
BOQ57_RS02865	COG0814	amino acid
BOQ57_RS02870	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOQ57_RS02875	COG3708	Transcriptional regulator
BOQ57_RS02875	COG2207	Transcriptional regulator
BOQ57_RS02885	COG0626	cystathionine gamma-synthase activity
BOQ57_RS02890	COG0460	homoserine dehydrogenase
BOQ57_RS02890	COG0527	aspartate kinase activity
BOQ57_RS02895	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BOQ57_RS02905	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BOQ57_RS02910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BOQ57_RS02920	COG0137	argininosuccinate synthase activity
BOQ57_RS02925	COG0165	Argininosuccinate lyase
BOQ57_RS02950	COG0110	maltose O-acetyltransferase activity
BOQ57_RS02955	COG3174	membrane
BOQ57_RS02960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BOQ57_RS02970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BOQ57_RS02975	COG4208	sulfate ABC transporter
BOQ57_RS02980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BOQ57_RS02985	COG0583	DNA-binding transcription factor activity
BOQ57_RS02990	COG3397	chitin binding
BOQ57_RS03030	COG4946	Tricorn protease homolog
BOQ57_RS03030	COG0793	Belongs to the peptidase S41A family
BOQ57_RS03050	COG1328	CTP reductase activity
BOQ57_RS03055	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BOQ57_RS03070	COG1448	Aminotransferase
BOQ57_RS03110	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS03130	COG0840	transmembrane signaling receptor activity
BOQ57_RS03145	COG3112	Uncharacterised protein family (UPF0231)
BOQ57_RS03155	COG3835	regulator
BOQ57_RS03160	COG2610	gluconate transmembrane transporter activity
BOQ57_RS03165	COG1929	Belongs to the glycerate kinase type-1 family
BOQ57_RS03180	COG0583	DNA-binding transcription factor activity
BOQ57_RS03185	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BOQ57_RS03200	COG0347	Belongs to the P(II) protein family
BOQ57_RS03205	COG1840	ABC-type Fe3 transport system, periplasmic component
BOQ57_RS03215	COG3842	ATPase activity
BOQ57_RS03220	COG2837	iron assimilation
BOQ57_RS03225	COG1438	arginine binding
BOQ57_RS03230	COG1126	abc transporter atp-binding protein
BOQ57_RS03235	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS03240	COG4215	(ABC) transporter
BOQ57_RS03245	COG4160	amino acid transport
BOQ57_RS03250	COG0039	L-malate dehydrogenase activity
BOQ57_RS03255	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BOQ57_RS03260	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BOQ57_RS03260	COG1017	nitric oxide dioxygenase activity
BOQ57_RS03265	COG1959	2 iron, 2 sulfur cluster binding
BOQ57_RS03270	COG4536	flavin adenine dinucleotide binding
BOQ57_RS03275	COG4137	Cytochrome C assembly protein
BOQ57_RS03280	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BOQ57_RS03285	COG0228	four-way junction DNA binding
BOQ57_RS03290	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BOQ57_RS03295	COG0336	Belongs to the RNA methyltransferase TrmD family
BOQ57_RS03300	COG0335	large ribosomal subunit rRNA binding
BOQ57_RS03310	COG3066	DNA modification
BOQ57_RS03320	COG1051	belongs to the nudix hydrolase family
BOQ57_RS03330	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BOQ57_RS03335	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BOQ57_RS03340	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BOQ57_RS03350	COG0583	DNA-binding transcription factor activity
BOQ57_RS03355	COG0640	Transcriptional regulator
BOQ57_RS03360	COG0268	Binds directly to 16S ribosomal RNA
BOQ57_RS03365	COG0728	peptidoglycan biosynthetic process
BOQ57_RS03370	COG0196	riboflavin kinase activity
BOQ57_RS03375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BOQ57_RS03380	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BOQ57_RS03385	COG1047	Peptidyl-prolyl cis-trans
BOQ57_RS03390	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BOQ57_RS03420	COG3039	Transposase
BOQ57_RS03440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BOQ57_RS03440	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BOQ57_RS03455	COG1854	S-ribosylhomocysteine lyase activity
BOQ57_RS03460	COG3706	GGDEF domain
BOQ57_RS03465	COG0557	exoribonuclease II activity
BOQ57_RS03470	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BOQ57_RS03480	COG2153	protein acetylation
BOQ57_RS03495	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BOQ57_RS03500	COG1914	H( )-stimulated, divalent metal cation uptake system
BOQ57_RS03505	COG0360	Binds together with S18 to 16S ribosomal RNA
BOQ57_RS03510	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BOQ57_RS03515	COG0359	binds to the 23S rRNA
BOQ57_RS03520	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BOQ57_RS03545	COG1238	metal cluster binding
BOQ57_RS03550	COG0612	Peptidase, M16
BOQ57_RS03555	COG2918	glutathione biosynthetic process
BOQ57_RS03565	COG1022	Amp-dependent synthetase and ligase
BOQ57_RS03575	COG0456	acetyltransferase
BOQ57_RS03585	COG0714	Associated with various cellular activities
BOQ57_RS03630	COG1902	pentaerythritol trinitrate reductase activity
BOQ57_RS03640	COG2852	Protein conserved in bacteria
BOQ57_RS03650	COG2957	Belongs to the agmatine deiminase family
BOQ57_RS03655	COG0154	amidase activity
BOQ57_RS03680	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS03700	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BOQ57_RS03705	COG1858	cytochrome C peroxidase
BOQ57_RS03730	COG2070	2-Nitropropane dioxygenase
BOQ57_RS03765	COG2816	NAD+ diphosphatase activity
BOQ57_RS03770	COG2205	protein histidine kinase activity
BOQ57_RS03775	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS03780	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS03785	COG1136	(ABC) transporter
BOQ57_RS03785	COG0577	efflux transmembrane transporter activity
BOQ57_RS03790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS03795	COG1126	abc transporter atp-binding protein
BOQ57_RS03800	COG0765	amino acid transport
BOQ57_RS03805	COG0765	amino acid transport
BOQ57_RS03810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BOQ57_RS03815	COG1505	serine-type exopeptidase activity
BOQ57_RS03835	COG1028	Short-chain dehydrogenase reductase Sdr
BOQ57_RS03840	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BOQ57_RS03855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOQ57_RS03860	COG4991	sh3 domain protein
BOQ57_RS03875	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BOQ57_RS03880	COG1940	carbohydrate kinase activity
BOQ57_RS03885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BOQ57_RS03890	COG0126	phosphoglycerate kinase activity
BOQ57_RS03900	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOQ57_RS03940	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BOQ57_RS03950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BOQ57_RS03955	COG1595	DNA-templated transcription, initiation
BOQ57_RS03960	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BOQ57_RS03975	COG0481	GTPase activity
BOQ57_RS03980	COG0681	Belongs to the peptidase S26 family
BOQ57_RS03985	COG0571	ribonuclease III activity
BOQ57_RS03995	COG1381	Involved in DNA repair and RecF pathway recombination
BOQ57_RS04000	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BOQ57_RS04015	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BOQ57_RS04020	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS04025	COG3716	PTS system mannose fructose sorbose family IID component
BOQ57_RS04035	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS04040	COG2222	sugar isomerase
BOQ57_RS04050	COG1349	DNA-binding transcription factor activity
BOQ57_RS04055	COG3023	N-Acetylmuramoyl-L-alanine amidase
BOQ57_RS04060	COG4807	Protein conserved in bacteria
BOQ57_RS04070	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BOQ57_RS04075	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BOQ57_RS04080	COG3956	TIGRFAM MazG family protein
BOQ57_RS04085	COG0504	CTP synthase activity
BOQ57_RS04090	COG0148	phosphopyruvate hydratase activity
BOQ57_RS04095	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BOQ57_RS04100	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BOQ57_RS04110	COG0585	pseudouridine synthase activity
BOQ57_RS04115	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BOQ57_RS04120	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BOQ57_RS04125	COG1238	metal cluster binding
BOQ57_RS04140	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BOQ57_RS04145	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BOQ57_RS04150	COG1610	YqeY-like protein
BOQ57_RS04155	COG0358	DNA primase activity
BOQ57_RS04160	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BOQ57_RS04185	COG0151	Belongs to the GarS family
BOQ57_RS04190	COG0138	bifunctional purine biosynthesis protein purh
BOQ57_RS04210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BOQ57_RS04215	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BOQ57_RS04225	COG0673	inositol 2-dehydrogenase activity
BOQ57_RS04235	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BOQ57_RS04240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BOQ57_RS04255	COG0477	Major facilitator Superfamily
BOQ57_RS04265	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BOQ57_RS04270	COG1027	Aspartate ammonia-lyase
BOQ57_RS04275	COG3030	protein affecting phage T7 exclusion by the F plasmid
BOQ57_RS04280	COG0534	Mate efflux family protein
BOQ57_RS04285	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BOQ57_RS04290	COG0459	protein refolding
BOQ57_RS04300	COG5001	Diguanylate cyclase
BOQ57_RS04300	COG3300	MHYT domain
BOQ57_RS04310	COG0564	pseudouridine synthase activity
BOQ57_RS04315	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BOQ57_RS04345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BOQ57_RS04355	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BOQ57_RS04360	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BOQ57_RS04365	COG1178	ABC-type Fe3 transport system permease component
BOQ57_RS04370	COG4143	(ABC) transporter
BOQ57_RS04385	COG0066	3-isopropylmalate dehydratase activity
BOQ57_RS04390	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BOQ57_RS04395	COG0473	3-isopropylmalate dehydrogenase activity
BOQ57_RS04400	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOQ57_RS04410	COG0671	phosphoesterase, PA-phosphatase related
BOQ57_RS04415	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BOQ57_RS04425	COG0028	Belongs to the TPP enzyme family
BOQ57_RS04435	COG0857	belongs to the CobB CobQ family
BOQ57_RS04435	COG0280	phosphate acetyltransferase
BOQ57_RS04440	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BOQ57_RS04450	COG3013	Belongs to the UPF0304 family
BOQ57_RS04455	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BOQ57_RS04460	COG2716	regulation of RNA biosynthetic process
BOQ57_RS04470	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BOQ57_RS04475	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BOQ57_RS04490	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BOQ57_RS04510	COG0784	Response regulator, receiver
BOQ57_RS04510	COG2198	Histidine kinase
BOQ57_RS04510	COG5002	protein histidine kinase activity
BOQ57_RS04535	COG0840	transmembrane signaling receptor activity
BOQ57_RS04545	COG1464	Belongs to the NlpA lipoprotein family
BOQ57_RS04550	COG2011	ABC-type metal ion transport system permease component
BOQ57_RS04555	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BOQ57_RS04575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BOQ57_RS04580	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BOQ57_RS04580	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BOQ57_RS04585	COG0802	atpase or kinase
BOQ57_RS04595	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BOQ57_RS04600	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BOQ57_RS04605	COG1923	regulation of RNA biosynthetic process
BOQ57_RS04610	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BOQ57_RS04615	COG0330	HflC and HflK could
BOQ57_RS04620	COG0330	HflC and HflK could
BOQ57_RS04625	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BOQ57_RS04630	COG0142	geranyltranstransferase activity
BOQ57_RS04635	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BOQ57_RS04640	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BOQ57_RS04645	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BOQ57_RS04650	COG3314	Sporulation integral membrane protein YlbJ
BOQ57_RS04655	COG0318	PFAM AMP-dependent synthetase and ligase
BOQ57_RS04670	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BOQ57_RS04675	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BOQ57_RS04685	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BOQ57_RS04690	COG2967	ApaG domain
BOQ57_RS04695	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BOQ57_RS04700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BOQ57_RS04710	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BOQ57_RS04715	COG3178	'Phosphotransferase
BOQ57_RS04720	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BOQ57_RS04725	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BOQ57_RS04730	COG2252	PERMEase
BOQ57_RS04740	COG0488	(ABC) transporter
BOQ57_RS04755	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BOQ57_RS04760	COG0741	lytic transglycosylase activity
BOQ57_RS04780	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BOQ57_RS04785	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BOQ57_RS04790	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BOQ57_RS04815	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOQ57_RS04825	COG3721	Heme iron utilization protein
BOQ57_RS04830	COG0748	coenzyme F420 binding
BOQ57_RS04850	COG4771	TonB-dependent receptor
BOQ57_RS04860	COG2814	Major facilitator Superfamily
BOQ57_RS04865	COG3655	Transcriptional regulator
BOQ57_RS04875	COG2202	Pas domain
BOQ57_RS04875	COG2205	protein histidine kinase activity
BOQ57_RS04890	COG3397	chitin binding
BOQ57_RS04895	COG2226	methyltransferase
BOQ57_RS04905	COG1765	OsmC-like protein
BOQ57_RS04920	COG3954	Phosphoribulokinase
BOQ57_RS04925	COG2076	Multidrug Resistance protein
BOQ57_RS04930	COG2076	Multidrug Resistance protein
BOQ57_RS04935	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BOQ57_RS04940	COG0726	polysaccharide deacetylase
BOQ57_RS04945	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BOQ57_RS04945	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOQ57_RS04950	COG0463	Glycosyl transferase, family 2
BOQ57_RS04955	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BOQ57_RS04965	COG3089	Belongs to the UPF0270 family
BOQ57_RS04970	COG2203	Gaf domain
BOQ57_RS04970	COG5001	Diguanylate cyclase
BOQ57_RS04970	COG3706	GGDEF domain
BOQ57_RS04970	COG4251	negative regulation of phosphorylation
BOQ57_RS04975	COG0429	hydrolase of the alpha beta-hydrolase fold
BOQ57_RS04980	COG0835	chemotaxis
BOQ57_RS04980	COG0784	Response regulator, receiver
BOQ57_RS04990	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BOQ57_RS04995	COG1047	Peptidyl-prolyl cis-trans
BOQ57_RS05010	COG0545	Peptidyl-prolyl cis-trans isomerase
BOQ57_RS05015	COG2204	response regulator
BOQ57_RS05035	COG0737	Belongs to the 5'-nucleotidase family
BOQ57_RS05040	COG2200	EAL domain
BOQ57_RS05060	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BOQ57_RS05065	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BOQ57_RS05070	COG0826	peptidase U32
BOQ57_RS05075	COG2203	Gaf domain
BOQ57_RS05075	COG2199	diguanylate cyclase activity
BOQ57_RS05075	COG2200	EAL domain
BOQ57_RS05090	COG3188	usher protein
BOQ57_RS05100	COG2197	response regulator
BOQ57_RS05110	COG1484	DNA-dependent DNA replication
BOQ57_RS05115	COG4584	PFAM Integrase catalytic
BOQ57_RS05145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BOQ57_RS05150	COG2201	protein-glutamate methylesterase activity
BOQ57_RS05155	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BOQ57_RS05165	COG0840	transmembrane signaling receptor activity
BOQ57_RS05170	COG0835	chemotaxis
BOQ57_RS05180	COG2198	Histidine kinase
BOQ57_RS05180	COG0643	Histidine kinase
BOQ57_RS05195	COG0840	transmembrane signaling receptor activity
BOQ57_RS05200	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BOQ57_RS05210	COG1280	lysine exporter protein (LysE YggA)
BOQ57_RS05220	COG0826	peptidase U32
BOQ57_RS05230	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BOQ57_RS05245	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BOQ57_RS05270	COG0300	oxidoreductase activity
BOQ57_RS05280	COG0840	transmembrane signaling receptor activity
BOQ57_RS05310	COG0077	Prephenate dehydratase
BOQ57_RS05310	COG1605	Chorismate mutase
BOQ57_RS05340	COG3272	Protein of unknown function (DUF1722)
BOQ57_RS05345	COG0789	Transcriptional regulator
BOQ57_RS05350	COG0415	Belongs to the DNA photolyase family
BOQ57_RS05360	COG4221	oxidoreductase activity
BOQ57_RS05375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BOQ57_RS05400	COG0783	Belongs to the Dps family
BOQ57_RS05405	COG1151	hydroxylamine reductase activity
BOQ57_RS05415	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BOQ57_RS05420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BOQ57_RS05420	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BOQ57_RS05435	COG2771	luxR family
BOQ57_RS05450	COG3501	Rhs element vgr protein
BOQ57_RS05495	COG0693	protein deglycase activity
BOQ57_RS05500	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BOQ57_RS05505	COG1666	GTP binding
BOQ57_RS05510	COG3248	Nucleoside-binding outer membrane protein
BOQ57_RS05515	COG2211	Major facilitator Superfamily
BOQ57_RS05525	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BOQ57_RS05535	COG2813	Specifically methylates the guanine in position
BOQ57_RS05540	COG0271	Belongs to the BolA IbaG family
BOQ57_RS05545	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BOQ57_RS05550	COG1805	sodium ion transport
BOQ57_RS05555	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BOQ57_RS05560	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BOQ57_RS05565	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BOQ57_RS05570	COG2871	sodium ion transport
BOQ57_RS05575	COG1477	protein flavinylation
BOQ57_RS05590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BOQ57_RS05595	COG0840	transmembrane signaling receptor activity
BOQ57_RS05600	COG0583	DNA-binding transcription factor activity
BOQ57_RS05610	COG2363	Small membrane protein
BOQ57_RS05615	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BOQ57_RS05625	COG0473	3-isopropylmalate dehydrogenase activity
BOQ57_RS05630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BOQ57_RS05635	COG1611	Belongs to the LOG family
BOQ57_RS05650	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BOQ57_RS05650	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BOQ57_RS05660	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BOQ57_RS05685	COG3098	single-species biofilm formation
BOQ57_RS05690	COG0564	pseudouridine synthase activity
BOQ57_RS05700	COG4580	involved in the transport of maltose and maltodextrins
BOQ57_RS05710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS05710	COG1263	PTS System
BOQ57_RS05720	COG2171	N-acyltransferase activity
BOQ57_RS05725	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BOQ57_RS05730	COG0024	Methionine aminopeptidase
BOQ57_RS05735	COG0052	Belongs to the universal ribosomal protein uS2 family
BOQ57_RS05740	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BOQ57_RS05745	COG0528	UMP kinase activity
BOQ57_RS05750	COG0233	cytoplasmic translational termination
BOQ57_RS05755	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BOQ57_RS05760	COG0575	Belongs to the CDS family
BOQ57_RS05765	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BOQ57_RS05770	COG0750	zinc metalloprotease
BOQ57_RS05785	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOQ57_RS05790	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BOQ57_RS05795	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOQ57_RS05800	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOQ57_RS05805	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BOQ57_RS05815	COG0825	malonyl-CoA metabolic process
BOQ57_RS05820	COG3710	Transcriptional regulator
BOQ57_RS05825	COG0531	amino acid
BOQ57_RS05830	COG1982	Orn Lys Arg decarboxylase major
BOQ57_RS05835	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BOQ57_RS05850	COG0814	amino acid
BOQ57_RS05855	COG1234	tRNA 3'-trailer cleavage
BOQ57_RS05865	COG1073	alpha beta
BOQ57_RS05870	COG1073	alpha beta
BOQ57_RS05880	COG0531	amino acid
BOQ57_RS05890	COG0488	(ABC) transporter
BOQ57_RS05900	COG3590	peptidase
BOQ57_RS05905	COG0037	tRNA processing
BOQ57_RS05910	COG3706	GGDEF domain
BOQ57_RS05945	COG0366	Alpha amylase catalytic
BOQ57_RS05960	COG0463	Glycosyl transferase, family 2
BOQ57_RS05975	COG2989	Protein conserved in bacteria
BOQ57_RS05980	COG3108	Peptidase M15
BOQ57_RS05990	COG2860	membrane
BOQ57_RS06000	COG1196	nuclear chromosome segregation
BOQ57_RS06005	COG3115	cell septum assembly
BOQ57_RS06010	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BOQ57_RS06020	COG1328	CTP reductase activity
BOQ57_RS06025	COG0602	queuosine metabolic process
BOQ57_RS06055	COG1566	PFAM secretion protein HlyD family protein
BOQ57_RS06060	COG1846	Transcriptional regulator
BOQ57_RS06075	COG0281	malic enzyme
BOQ57_RS06080	COG3290	protein histidine kinase activity
BOQ57_RS06085	COG4565	transcriptional regulatory protein
BOQ57_RS06090	COG0697	spore germination
BOQ57_RS06105	COG3284	Transcriptional regulator
BOQ57_RS06110	COG1960	acyl-CoA dehydrogenase activity
BOQ57_RS06115	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BOQ57_RS06120	COG0346	lactoylglutathione lyase activity
BOQ57_RS06125	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS06130	COG5002	protein histidine kinase activity
BOQ57_RS06155	COG3142	Participates in the control of copper homeostasis
BOQ57_RS06165	COG0545	Peptidyl-prolyl cis-trans isomerase
BOQ57_RS06170	COG1131	(ABC) transporter
BOQ57_RS06190	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BOQ57_RS06200	COG0678	peroxiredoxin activity
BOQ57_RS06210	COG0019	diaminopimelate decarboxylase activity
BOQ57_RS06215	COG1115	amino acid carrier protein
BOQ57_RS06220	COG0095	Lipoate-protein ligase
BOQ57_RS06225	COG2233	PERMEase
BOQ57_RS06240	COG0534	Mate efflux family protein
BOQ57_RS06250	COG0281	malic enzyme
BOQ57_RS06280	COG0733	neurotransmitter:sodium symporter activity
BOQ57_RS06285	COG1752	Esterase of the alpha-beta hydrolase superfamily
BOQ57_RS06295	COG1566	PFAM secretion protein HlyD family protein
BOQ57_RS06300	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOQ57_RS06310	COG1032	radical SAM domain protein
BOQ57_RS06330	COG3152	Membrane
BOQ57_RS06350	COG0673	inositol 2-dehydrogenase activity
BOQ57_RS06360	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BOQ57_RS06365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BOQ57_RS06370	COG1196	nuclear chromosome segregation
BOQ57_RS06370	COG0741	lytic transglycosylase activity
BOQ57_RS06370	COG0739	heme binding
BOQ57_RS06375	COG0366	Alpha amylase catalytic
BOQ57_RS06395	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BOQ57_RS06405	COG0788	formyltetrahydrofolate deformylase activity
BOQ57_RS06410	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BOQ57_RS06420	COG3118	belongs to the thioredoxin family
BOQ57_RS06425	COG2091	lysine biosynthetic process via aminoadipic acid
BOQ57_RS06430	COG0791	NLP P60 protein
BOQ57_RS06435	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BOQ57_RS06450	COG1388	LysM domain
BOQ57_RS06450	COG1376	ErfK ybiS ycfS ynhG family protein
BOQ57_RS06460	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOQ57_RS06465	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS06470	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS06475	COG5002	protein histidine kinase activity
BOQ57_RS06495	COG4869	propanediol catabolic process
BOQ57_RS06505	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BOQ57_RS06510	COG1882	Formate acetyltransferase
BOQ57_RS06515	COG1454	alcohol dehydrogenase
BOQ57_RS06515	COG1012	belongs to the aldehyde dehydrogenase family
BOQ57_RS06525	COG1454	alcohol dehydrogenase
BOQ57_RS06525	COG1012	belongs to the aldehyde dehydrogenase family
BOQ57_RS06560	COG0583	DNA-binding transcription factor activity
BOQ57_RS06565	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BOQ57_RS06570	COG0243	molybdopterin cofactor binding
BOQ57_RS06580	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BOQ57_RS06590	COG1960	acyl-CoA dehydrogenase activity
BOQ57_RS06595	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOQ57_RS06605	COG0469	pyruvate kinase activity
BOQ57_RS06610	COG1737	Transcriptional regulator
BOQ57_RS06630	COG2274	protein secretion by the type I secretion system
BOQ57_RS06640	COG2274	protein secretion by the type I secretion system
BOQ57_RS06650	COG2994	toxin metabolic process
BOQ57_RS06655	COG3064	Membrane
BOQ57_RS06655	COG1073	alpha beta
BOQ57_RS06655	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BOQ57_RS06665	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BOQ57_RS06680	COG1677	Flagellar hook-basal body complex protein FliE
BOQ57_RS06690	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BOQ57_RS06745	COG1684	flagellar biosynthetic protein fliR
BOQ57_RS06755	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BOQ57_RS06780	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BOQ57_RS06785	COG2198	Histidine kinase
BOQ57_RS06785	COG0784	Response regulator, receiver
BOQ57_RS06785	COG0643	Histidine kinase
BOQ57_RS06790	COG2201	protein-glutamate methylesterase activity
BOQ57_RS06795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BOQ57_RS06800	COG1360	Flagellar Motor Protein
BOQ57_RS06805	COG1192	Involved in chromosome partitioning
BOQ57_RS06815	COG0835	chemotaxis
BOQ57_RS06830	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BOQ57_RS06835	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BOQ57_RS06840	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BOQ57_RS06845	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BOQ57_RS06850	COG1138	Cytochrome C-type biogenesis protein
BOQ57_RS06855	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOQ57_RS06860	COG3088	subunit of a heme lyase
BOQ57_RS06860	COG4235	cytochrome complex assembly
BOQ57_RS06865	COG4235	cytochrome complex assembly
BOQ57_RS06865	COG3088	subunit of a heme lyase
BOQ57_RS06880	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BOQ57_RS06885	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BOQ57_RS06885	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BOQ57_RS06900	COG0259	pyridoxamine-phosphate oxidase activity
BOQ57_RS06905	COG0625	glutathione transferase activity
BOQ57_RS06915	COG3153	acetyltransferase
BOQ57_RS06925	COG2850	peptidyl-arginine hydroxylation
BOQ57_RS06930	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BOQ57_RS06935	COG2915	High frequency lysogenization protein hflD homolog
BOQ57_RS06940	COG0482	sulfurtransferase activity
BOQ57_RS06950	COG1187	pseudouridine synthase activity
BOQ57_RS06960	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BOQ57_RS06960	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS06960	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BOQ57_RS06970	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BOQ57_RS06970	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BOQ57_RS06970	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS06990	COG0456	acetyltransferase
BOQ57_RS07000	COG0789	Transcriptional regulator
BOQ57_RS07010	COG1609	Transcriptional regulator
BOQ57_RS07015	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS07015	COG1263	PTS System
BOQ57_RS07020	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BOQ57_RS07030	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BOQ57_RS07050	COG2207	Transcriptional regulator
BOQ57_RS07055	COG0538	isocitrate dehydrogenase activity
BOQ57_RS07065	COG3048	D-serine ammonia-lyase activity
BOQ57_RS07070	COG0583	DNA-binding transcription factor activity
BOQ57_RS07075	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BOQ57_RS07090	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BOQ57_RS07095	COG2867	negative regulation of translational initiation
BOQ57_RS07100	COG2914	Belongs to the UPF0125 (RnfH) family
BOQ57_RS07105	COG0702	epimerase
BOQ57_RS07110	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOQ57_RS07115	COG1454	alcohol dehydrogenase
BOQ57_RS07125	COG0564	pseudouridine synthase activity
BOQ57_RS07155	COG1280	lysine exporter protein (LysE YggA)
BOQ57_RS07165	COG3263	regulation of cellular component size
BOQ57_RS07175	COG3263	regulation of cellular component size
BOQ57_RS07185	COG1876	peptidase activity
BOQ57_RS07190	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BOQ57_RS07195	COG1393	Belongs to the ArsC family
BOQ57_RS07200	COG0583	DNA-binding transcription factor activity
BOQ57_RS07210	COG3069	C4-dicarboxylate transmembrane transporter activity
BOQ57_RS07225	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BOQ57_RS07230	COG0017	Asparaginyl-tRNA synthetase
BOQ57_RS07250	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BOQ57_RS07255	COG0156	8-amino-7-oxononanoate synthase activity
BOQ57_RS07260	COG2226	methyltransferase
BOQ57_RS07260	COG1073	alpha beta
BOQ57_RS07265	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BOQ57_RS07270	COG0501	Belongs to the peptidase M48B family
BOQ57_RS07280	COG0633	Ferredoxin
BOQ57_RS07280	COG3217	Mosc domain protein beta barrel domain protein
BOQ57_RS07280	COG0633	Ferredoxin
BOQ57_RS07280	COG3217	Mosc domain protein beta barrel domain protein
BOQ57_RS07290	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BOQ57_RS07290	COG1013	pyruvate-flavodoxin oxidoreductase activity
BOQ57_RS07290	COG0674	pyruvate-flavodoxin oxidoreductase activity
BOQ57_RS07290	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BOQ57_RS07310	COG0534	Mate efflux family protein
BOQ57_RS07350	COG1309	transcriptional regulator
BOQ57_RS07365	COG0791	NLP P60 protein
BOQ57_RS07375	COG0583	DNA-binding transcription factor activity
BOQ57_RS07380	COG0450	alkyl hydroperoxide reductase
BOQ57_RS07400	COG0500	methyltransferase
BOQ57_RS07405	COG4106	trans-aconitate 2-methyltransferase activity
BOQ57_RS07415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BOQ57_RS07420	COG0217	transcriptional regulatory protein
BOQ57_RS07425	COG2194	sulfuric ester hydrolase activity
BOQ57_RS07430	COG1940	carbohydrate kinase activity
BOQ57_RS07430	COG1846	Transcriptional regulator
BOQ57_RS07435	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BOQ57_RS07440	COG0363	glucosamine-6-phosphate deaminase activity
BOQ57_RS07445	COG2190	(PTS) system
BOQ57_RS07445	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS07445	COG1263	PTS System
BOQ57_RS07455	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOQ57_RS07460	COG0735	belongs to the Fur family
BOQ57_RS07470	COG0716	FMN binding
BOQ57_RS07485	COG0596	Alpha beta hydrolase
BOQ57_RS07490	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BOQ57_RS07495	COG0033	Phosphoglucomutase
BOQ57_RS07505	COG1846	Transcriptional regulator
BOQ57_RS07520	COG2951	lytic endotransglycosylase activity
BOQ57_RS07525	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BOQ57_RS07530	COG4136	ATPase activity
BOQ57_RS07540	COG4134	Bacterial extracellular solute-binding protein
BOQ57_RS07550	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BOQ57_RS07560	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BOQ57_RS07565	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOQ57_RS07575	COG0729	surface antigen
BOQ57_RS07580	COG2911	Protein conserved in bacteria
BOQ57_RS07600	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BOQ57_RS07610	COG0741	lytic transglycosylase activity
BOQ57_RS07625	COG1607	acyl-coa hydrolase
BOQ57_RS07635	COG3021	interspecies interaction between organisms
BOQ57_RS07640	COG0741	lytic transglycosylase activity
BOQ57_RS07640	COG1388	LysM domain
BOQ57_RS07645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOQ57_RS07650	COG2226	methyltransferase
BOQ57_RS07655	COG0328	RNA-DNA hybrid ribonuclease activity
BOQ57_RS07670	COG3437	response regulator, receiver
BOQ57_RS07670	COG0784	Response regulator, receiver
BOQ57_RS07675	COG1960	acyl-CoA dehydrogenase activity
BOQ57_RS07680	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BOQ57_RS07685	COG0121	glutamine amidotransferase
BOQ57_RS07715	COG2197	response regulator
BOQ57_RS07720	COG3850	Histidine kinase
BOQ57_RS07725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BOQ57_RS07730	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BOQ57_RS07730	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BOQ57_RS07740	COG0243	molybdopterin cofactor binding
BOQ57_RS07745	COG0437	4 iron, 4 sulfur cluster binding
BOQ57_RS07750	COG0348	domain, Protein
BOQ57_RS07760	COG3005	denitrification pathway
BOQ57_RS07765	COG0521	Mo-molybdopterin cofactor biosynthetic process
BOQ57_RS07770	COG0315	cyclic pyranopterin monophosphate synthase activity
BOQ57_RS07775	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BOQ57_RS07780	COG0314	molybdopterin synthase activity
BOQ57_RS07795	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BOQ57_RS07800	COG2267	carboxylic ester hydrolase activity
BOQ57_RS07805	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BOQ57_RS07815	COG0302	gtp cyclohydrolase
BOQ57_RS07820	COG0840	transmembrane signaling receptor activity
BOQ57_RS07825	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BOQ57_RS07835	COG0583	DNA-binding transcription factor activity
BOQ57_RS07865	COG2195	Cleaves the N-terminal amino acid of tripeptides
BOQ57_RS07880	COG1166	arginine decarboxylase activity
BOQ57_RS07900	COG0814	amino acid
BOQ57_RS07910	COG3681	Belongs to the UPF0597 family
BOQ57_RS07915	COG2964	Protein conserved in bacteria
BOQ57_RS07925	COG1403	HNH endonuclease
BOQ57_RS07935	COG0346	lactoylglutathione lyase activity
BOQ57_RS07955	COG1187	pseudouridine synthase activity
BOQ57_RS07965	COG2807	transmembrane transport
BOQ57_RS07975	COG0583	DNA-binding transcription factor activity
BOQ57_RS07980	COG2271	Major facilitator Superfamily
BOQ57_RS08005	COG2979	Protein of unknown function (DUF533)
BOQ57_RS08015	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOQ57_RS08020	COG1271	oxidase subunit
BOQ57_RS08025	COG1294	oxidase, subunit
BOQ57_RS08035	COG2814	Major facilitator Superfamily
BOQ57_RS08040	COG0656	L-ascorbic acid biosynthetic process
BOQ57_RS08065	COG0583	DNA-binding transcription factor activity
BOQ57_RS08070	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BOQ57_RS08075	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BOQ57_RS08080	COG2271	Major facilitator Superfamily
BOQ57_RS08085	COG1349	DNA-binding transcription factor activity
BOQ57_RS08095	COG0584	glycerophosphoryl diester phosphodiesterase
BOQ57_RS08100	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BOQ57_RS08105	COG0287	Prephenate dehydrogenase
BOQ57_RS08105	COG1605	Chorismate mutase
BOQ57_RS08110	COG0583	DNA-binding transcription factor activity
BOQ57_RS08115	COG3085	chromosome segregation
BOQ57_RS08120	COG4574	serine-type endopeptidase inhibitor activity
BOQ57_RS08140	COG1770	oligopeptidase
BOQ57_RS08145	COG4771	TonB-dependent receptor
BOQ57_RS08150	COG3083	sulfuric ester hydrolase activity
BOQ57_RS08155	COG3082	Protein of unknown function (DUF1414)
BOQ57_RS08160	COG3081	Nucleoid-associated protein
BOQ57_RS08170	COG1175	transmembrane transport
BOQ57_RS08175	COG3833	ABC-type maltose transport systems, permease component
BOQ57_RS08180	COG3842	ATPase activity
BOQ57_RS08205	COG0425	Belongs to the sulfur carrier protein TusA family
BOQ57_RS08210	COG4783	chaperone-mediated protein folding
BOQ57_RS08220	COG1393	Belongs to the ArsC family
BOQ57_RS08235	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BOQ57_RS08240	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BOQ57_RS08245	COG2431	L-lysine efflux transmembrane transporter activity
BOQ57_RS08255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS08275	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BOQ57_RS08285	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOQ57_RS08290	COG2373	Large extracellular alpha-helical protein
BOQ57_RS08295	COG4953	penicillin-binding protein 1C
BOQ57_RS08305	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BOQ57_RS08305	COG0301	tRNA thio-modification
BOQ57_RS08330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BOQ57_RS08360	COG1083	cytidylyl-transferase
BOQ57_RS08380	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BOQ57_RS08385	COG2089	acid synthase
BOQ57_RS08395	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BOQ57_RS08415	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BOQ57_RS08435	COG0483	inositol monophosphate 1-phosphatase activity
BOQ57_RS08445	COG0625	glutathione transferase activity
BOQ57_RS08450	COG2814	Major facilitator Superfamily
BOQ57_RS08470	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOQ57_RS08475	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOQ57_RS08480	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BOQ57_RS08485	COG0509	glycine decarboxylation via glycine cleavage system
BOQ57_RS08490	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BOQ57_RS08490	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BOQ57_RS08520	COG0798	PFAM Bile acid sodium symporter
BOQ57_RS08525	COG1393	Belongs to the ArsC family
BOQ57_RS08545	COG3634	alkyl hydroperoxide reductase activity
BOQ57_RS08555	COG0517	IMP dehydrogenase activity
BOQ57_RS08560	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BOQ57_RS08565	COG0343	queuine tRNA-ribosyltransferase activity
BOQ57_RS08570	COG1862	Preprotein translocase
BOQ57_RS08575	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOQ57_RS08580	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOQ57_RS08595	COG0826	peptidase U32
BOQ57_RS08600	COG0826	peptidase U32
BOQ57_RS08605	COG3154	lipid carrier protein
BOQ57_RS08625	COG1104	cysteine desulfurase activity
BOQ57_RS08630	COG0822	iron-sulfur transferase activity
BOQ57_RS08640	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BOQ57_RS08645	COG0443	Heat shock 70 kDa protein
BOQ57_RS08650	COG0633	Ferredoxin
BOQ57_RS08660	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BOQ57_RS08665	COG0105	UTP biosynthetic process
BOQ57_RS08670	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BOQ57_RS08685	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BOQ57_RS08690	COG0124	histidyl-tRNA synthetase
BOQ57_RS08695	COG2976	Protein conserved in bacteria
BOQ57_RS08700	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOQ57_RS08705	COG1160	GTP binding
BOQ57_RS08710	COG1645	bacterial-type flagellum-dependent swarming motility
BOQ57_RS08720	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BOQ57_RS08725	COG0047	phosphoribosylformylglycinamidine synthase activity
BOQ57_RS08725	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BOQ57_RS08730	COG1007	ATP synthesis coupled electron transport
BOQ57_RS08735	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOQ57_RS08745	COG0713	ATP synthesis coupled electron transport
BOQ57_RS08750	COG0839	Belongs to the complex I subunit 6 family
BOQ57_RS08755	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOQ57_RS08760	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BOQ57_RS08765	COG1034	ATP synthesis coupled electron transport
BOQ57_RS08780	COG0649	NAD binding
BOQ57_RS08780	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOQ57_RS08785	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOQ57_RS08790	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOQ57_RS08795	COG1360	Flagellar Motor Protein
BOQ57_RS08800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BOQ57_RS08820	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BOQ57_RS08840	COG0724	RNA recognition motif
BOQ57_RS08845	COG4989	oxidoreductase activity
BOQ57_RS08870	COG3437	response regulator, receiver
BOQ57_RS08875	COG0583	DNA-binding transcription factor activity
BOQ57_RS08885	COG3300	MHYT domain
BOQ57_RS08885	COG5001	Diguanylate cyclase
BOQ57_RS08890	COG0778	Nitroreductase
BOQ57_RS08910	COG0583	DNA-binding transcription factor activity
BOQ57_RS08920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BOQ57_RS08930	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BOQ57_RS08935	COG0539	negative regulation of cytoplasmic translation
BOQ57_RS08940	COG0776	regulation of translation
BOQ57_RS08950	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BOQ57_RS08970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BOQ57_RS08975	COG0602	queuosine metabolic process
BOQ57_RS08980	COG3530	Putative quorum-sensing-regulated virulence factor
BOQ57_RS08985	COG2096	Adenosyltransferase
BOQ57_RS08990	COG2916	Histone family protein nucleoid-structuring protein H-NS
BOQ57_RS08995	COG1757	Na H antiporter
BOQ57_RS09000	COG1435	thymidine kinase activity
BOQ57_RS09030	COG3501	Rhs element vgr protein
BOQ57_RS09105	COG3829	transcription factor binding
BOQ57_RS09160	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BOQ57_RS09165	COG1278	Cold shock
BOQ57_RS09170	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BOQ57_RS09175	COG0542	response to heat
BOQ57_RS09180	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BOQ57_RS09185	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BOQ57_RS09190	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BOQ57_RS09195	COG3134	Outer membrane lipoprotein
BOQ57_RS09200	COG3706	GGDEF domain
BOQ57_RS09205	COG0492	ferredoxin-NADP+ reductase activity
BOQ57_RS09210	COG0686	Belongs to the AlaDH PNT family
BOQ57_RS09220	COG1674	ftsk spoiiie
BOQ57_RS09220	COG0531	amino acid
BOQ57_RS09225	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BOQ57_RS09230	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BOQ57_RS09240	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BOQ57_RS09245	COG1286	toxin biosynthetic process
BOQ57_RS09250	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BOQ57_RS09260	COG4172	Belongs to the ABC transporter superfamily
BOQ57_RS09270	COG4171	peptide transport system, permease
BOQ57_RS09275	COG4168	peptide transport system, permease
BOQ57_RS09285	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BOQ57_RS09290	COG1842	Phage shock protein A
BOQ57_RS09305	COG3106	COG3106 Predicted ATPase
BOQ57_RS09310	COG3768	UPF0283 membrane protein
BOQ57_RS09320	COG2154	pterin-4-alpha-carbinolamine dehydratase
BOQ57_RS09345	COG2199	diguanylate cyclase activity
BOQ57_RS09350	COG2885	chlorophyll binding
BOQ57_RS09355	COG0861	Integral membrane protein TerC family
BOQ57_RS09370	COG1022	Amp-dependent synthetase and ligase
BOQ57_RS09375	COG0295	cytidine deaminase activity
BOQ57_RS09380	COG1346	cytolysis
BOQ57_RS09385	COG1380	Effector of murein hydrolase LrgA
BOQ57_RS09390	COG3345	alpha-galactosidase
BOQ57_RS09400	COG2925	Exonuclease
BOQ57_RS09405	COG0582	viral genome integration into host DNA
BOQ57_RS09440	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BOQ57_RS09455	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BOQ57_RS09460	COG1476	TRANSCRIPTIONal
BOQ57_RS09535	COG4220	transposase activity
BOQ57_RS09555	COG0740	serine-type endopeptidase activity
BOQ57_RS09640	COG2160	L-arabinose isomerase activity
BOQ57_RS09650	COG1069	ribulokinase activity
BOQ57_RS09655	COG1879	ABC-type sugar transport system periplasmic component
BOQ57_RS09665	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOQ57_RS09675	COG0583	DNA-binding transcription factor activity
BOQ57_RS09685	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BOQ57_RS09690	COG0254	rRNA binding
BOQ57_RS09705	COG1451	nucleotide metabolic process
BOQ57_RS09720	COG3069	C4-dicarboxylate transmembrane transporter activity
BOQ57_RS09730	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOQ57_RS09730	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BOQ57_RS09735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BOQ57_RS09760	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BOQ57_RS09765	COG1053	succinate dehydrogenase
BOQ57_RS09775	COG0567	Dehydrogenase, E1 component
BOQ57_RS09780	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOQ57_RS09785	COG0045	succinate-CoA ligase (ADP-forming) activity
BOQ57_RS09790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BOQ57_RS09800	COG2983	Belongs to the UPF0260 family
BOQ57_RS09805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOQ57_RS09815	COG3842	ATPase activity
BOQ57_RS09820	COG1840	ABC-type Fe3 transport system, periplasmic component
BOQ57_RS09830	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BOQ57_RS09835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BOQ57_RS09840	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOQ57_RS09845	COG1882	Formate acetyltransferase
BOQ57_RS09850	COG2116	formate transmembrane transporter activity
BOQ57_RS09855	COG1944	ATP diphosphatase activity
BOQ57_RS09865	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BOQ57_RS09870	COG0612	Peptidase, M16
BOQ57_RS09885	COG2910	NAD(P)H-binding
BOQ57_RS09890	COG0583	DNA-binding transcription factor activity
BOQ57_RS09900	COG4977	sequence-specific DNA binding
BOQ57_RS09905	COG4774	siderophore transport
BOQ57_RS09920	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BOQ57_RS09945	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOQ57_RS09950	COG3046	protein related to deoxyribodipyrimidine photolyase
BOQ57_RS09970	COG1051	belongs to the nudix hydrolase family
BOQ57_RS09975	COG4235	cytochrome complex assembly
BOQ57_RS09975	COG3088	subunit of a heme lyase
BOQ57_RS09980	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOQ57_RS09985	COG1138	Cytochrome C-type biogenesis protein
BOQ57_RS09990	COG3301	Polysulphide reductase, NrfD
BOQ57_RS09995	COG0437	4 iron, 4 sulfur cluster binding
BOQ57_RS10000	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BOQ57_RS10015	COG0247	lactate metabolic process
BOQ57_RS10020	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BOQ57_RS10025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BOQ57_RS10030	COG3012	SEC-C Motif Domain Protein
BOQ57_RS10035	COG0840	transmembrane signaling receptor activity
BOQ57_RS10040	COG1940	carbohydrate kinase activity
BOQ57_RS10040	COG1846	Transcriptional regulator
BOQ57_RS10045	COG3290	protein histidine kinase activity
BOQ57_RS10050	COG4565	transcriptional regulatory protein
BOQ57_RS10075	COG2985	domain, Protein
BOQ57_RS10075	COG0569	domain protein
BOQ57_RS10090	COG0556	nucleotide-excision repair
BOQ57_RS10100	COG0586	Pfam SNARE associated Golgi protein
BOQ57_RS10105	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BOQ57_RS10110	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BOQ57_RS10115	COG2186	Transcriptional regulator
BOQ57_RS10120	COG2719	SpoVR family
BOQ57_RS10130	COG2766	serine protein kinase
BOQ57_RS10135	COG0514	ATP-dependent DNA helicase (RecQ)
BOQ57_RS10140	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BOQ57_RS10145	COG0814	amino acid
BOQ57_RS10180	COG0058	SHG alpha-glucan phosphorylase activity
BOQ57_RS10185	COG0471	metal ion transport
BOQ57_RS10190	COG3118	belongs to the thioredoxin family
BOQ57_RS10200	COG1132	(ABC) transporter
BOQ57_RS10210	COG1132	(ABC) transporter
BOQ57_RS10220	COG2501	S4 domain
BOQ57_RS10230	COG3243	poly(R)-hydroxyalkanoic acid synthase
BOQ57_RS10250	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BOQ57_RS10255	COG2329	Antibiotic biosynthesis monooxygenase
BOQ57_RS10285	COG1742	UPF0060 membrane protein
BOQ57_RS10295	COG0456	acetyltransferase
BOQ57_RS10300	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS10305	COG0386	Belongs to the glutathione peroxidase family
BOQ57_RS10315	COG1181	Belongs to the D-alanine--D-alanine ligase family
BOQ57_RS10325	COG3148	PFAM DTW domain containing protein
BOQ57_RS10330	COG0730	response to heat
BOQ57_RS10335	COG0583	DNA-binding transcription factor activity
BOQ57_RS10350	COG3593	DNA synthesis involved in DNA repair
BOQ57_RS10400	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BOQ57_RS10405	COG1011	Hydrolase
BOQ57_RS10410	COG1473	amidohydrolase
BOQ57_RS10415	COG0205	6-phosphofructokinase activity
BOQ57_RS10425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BOQ57_RS10430	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BOQ57_RS10440	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BOQ57_RS10445	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BOQ57_RS10465	COG0242	peptide deformylase activity
BOQ57_RS10495	COG0384	phenazine biosynthesis protein PhzF
BOQ57_RS10510	COG2824	Alkylphosphonate utilization operon protein PhnA
BOQ57_RS10535	COG0406	alpha-ribazole phosphatase activity
BOQ57_RS10540	COG3706	GGDEF domain
BOQ57_RS10550	COG2840	Smr protein MutS2
BOQ57_RS10555	COG2890	protein-(glutamine-N5) methyltransferase activity
BOQ57_RS10560	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BOQ57_RS10570	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS10575	COG5654	RES domain protein
BOQ57_RS10585	COG0814	amino acid
BOQ57_RS10590	COG1609	Transcriptional regulator
BOQ57_RS10595	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS10595	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS10600	COG1105	Belongs to the carbohydrate kinase PfkB family
BOQ57_RS10605	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BOQ57_RS10605	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BOQ57_RS10605	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BOQ57_RS10610	COG2140	Oxalate decarboxylase
BOQ57_RS10615	COG1609	Transcriptional regulator
BOQ57_RS10630	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS10630	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS10635	COG3715	PTS system
BOQ57_RS10640	COG3716	PTS system mannose fructose sorbose family IID component
BOQ57_RS10645	COG2942	2-epimerase
BOQ57_RS10650	COG3313	Fe-S protein
BOQ57_RS10655	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BOQ57_RS10660	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BOQ57_RS10665	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BOQ57_RS10670	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BOQ57_RS10680	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BOQ57_RS10700	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BOQ57_RS10705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BOQ57_RS10710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BOQ57_RS10715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BOQ57_RS10720	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BOQ57_RS10725	COG0072	phenylalanine-tRNA ligase activity
BOQ57_RS10725	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOQ57_RS10730	COG0776	regulation of translation
BOQ57_RS10760	COG5001	Diguanylate cyclase
BOQ57_RS10760	COG3300	MHYT domain
BOQ57_RS10765	COG1609	Transcriptional regulator
BOQ57_RS10770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOQ57_RS10775	COG1879	ABC-type sugar transport system periplasmic component
BOQ57_RS10780	COG1172	Belongs to the binding-protein-dependent transport system permease family
BOQ57_RS10785	COG1129	ABC transporter
BOQ57_RS10790	COG1869	D-ribose catabolic process
BOQ57_RS10795	COG0625	glutathione transferase activity
BOQ57_RS10810	COG0037	tRNA processing
BOQ57_RS10815	COG0589	response to stress
BOQ57_RS10820	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BOQ57_RS10845	COG2010	Cytochrome c
BOQ57_RS10860	COG3278	Belongs to the heme-copper respiratory oxidase family
BOQ57_RS10870	COG1956	GAF domain-containing protein
BOQ57_RS10875	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BOQ57_RS10885	COG0308	aminopeptidase N
BOQ57_RS10895	COG2902	Dehydrogenase
BOQ57_RS10900	COG0167	dihydroorotate dehydrogenase activity
BOQ57_RS10910	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BOQ57_RS10910	COG0116	Belongs to the methyltransferase superfamily
BOQ57_RS10920	COG0488	(ABC) transporter
BOQ57_RS10935	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BOQ57_RS10940	COG1067	ATP-dependent peptidase activity
BOQ57_RS11000	COG3141	response to X-ray
BOQ57_RS11010	COG4221	oxidoreductase activity
BOQ57_RS11055	COG0372	Belongs to the citrate synthase family
BOQ57_RS11060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BOQ57_RS11070	COG2995	paraquat-inducible protein a
BOQ57_RS11075	COG3008	intermembrane lipid transfer
BOQ57_RS11080	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BOQ57_RS11080	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BOQ57_RS11095	COG0084	hydrolase, TatD family'
BOQ57_RS11100	COG0470	DNA polymerase III
BOQ57_RS11105	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BOQ57_RS11110	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BOQ57_RS11115	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BOQ57_RS11125	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOQ57_RS11130	COG1028	Short-chain dehydrogenase reductase Sdr
BOQ57_RS11140	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BOQ57_RS11145	COG0416	fatty acid biosynthetic process
BOQ57_RS11150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BOQ57_RS11155	COG1399	metal-binding, possibly nucleic acid-binding protein
BOQ57_RS11170	COG2814	Major facilitator Superfamily
BOQ57_RS11175	COG0424	maF-like protein
BOQ57_RS11180	COG0546	phosphoglycolate phosphatase activity
BOQ57_RS11185	COG0564	pseudouridine synthase activity
BOQ57_RS11190	COG1530	ribonuclease E activity
BOQ57_RS11205	COG0697	spore germination
BOQ57_RS11295	COG0110	maltose O-acetyltransferase activity
BOQ57_RS11350	COG1660	Displays ATPase and GTPase activities
BOQ57_RS11420	COG1695	Transcriptional regulator
BOQ57_RS11455	COG3173	Aminoglycoside phosphotransferase
BOQ57_RS11475	COG4974	Belongs to the 'phage' integrase family
BOQ57_RS11490	COG3173	Aminoglycoside phosphotransferase
BOQ57_RS11510	COG5001	Diguanylate cyclase
BOQ57_RS11510	COG3300	MHYT domain
BOQ57_RS11550	COG0306	phosphate transporter
BOQ57_RS11555	COG0717	Belongs to the dCTP deaminase family
BOQ57_RS11560	COG0572	uridine kinase
BOQ57_RS11565	COG0489	protein tyrosine kinase activity
BOQ57_RS11570	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOQ57_RS11570	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BOQ57_RS11575	COG0625	glutathione transferase activity
BOQ57_RS11580	COG1254	Belongs to the acylphosphatase family
BOQ57_RS11590	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BOQ57_RS11605	COG0709	Synthesizes selenophosphate from selenide and ATP
BOQ57_RS11610	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BOQ57_RS11615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BOQ57_RS11620	COG3437	response regulator, receiver
BOQ57_RS11630	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BOQ57_RS11640	COG1643	Atp-dependent helicase
BOQ57_RS11645	COG0517	IMP dehydrogenase activity
BOQ57_RS11645	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BOQ57_RS11645	COG0617	tRNA 3'-terminal CCA addition
BOQ57_RS11660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BOQ57_RS11670	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BOQ57_RS11675	COG2832	Protein of unknown function (DUF454)
BOQ57_RS11680	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BOQ57_RS11695	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BOQ57_RS11700	COG0318	PFAM AMP-dependent synthetase and ligase
BOQ57_RS11705	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BOQ57_RS11705	COG0596	Alpha beta hydrolase
BOQ57_RS11705	COG2226	methyltransferase
BOQ57_RS11715	COG1214	PFAM Peptidase M22, glycoprotease
BOQ57_RS11720	COG1199	ATP-dependent helicase activity
BOQ57_RS11730	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BOQ57_RS11735	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BOQ57_RS11740	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BOQ57_RS11745	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BOQ57_RS11745	COG0131	Imidazoleglycerol-phosphate dehydratase
BOQ57_RS11750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BOQ57_RS11755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BOQ57_RS11760	COG3437	response regulator, receiver
BOQ57_RS11765	COG2199	diguanylate cyclase activity
BOQ57_RS11770	COG0784	Response regulator, receiver
BOQ57_RS11770	COG2205	protein histidine kinase activity
BOQ57_RS11770	COG2198	Histidine kinase
BOQ57_RS11775	COG0107	imidazoleglycerol-phosphate synthase activity
BOQ57_RS11780	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BOQ57_RS11780	COG0140	phosphoribosyl-ATP diphosphatase activity
BOQ57_RS11785	COG0318	PFAM AMP-dependent synthetase and ligase
BOQ57_RS11790	COG1288	antiporter activity
BOQ57_RS11800	COG3134	Outer membrane lipoprotein
BOQ57_RS11810	COG2080	2 iron, 2 sulfur cluster binding
BOQ57_RS11815	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BOQ57_RS11820	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOQ57_RS11825	COG2252	PERMEase
BOQ57_RS11830	COG0402	S-adenosylhomocysteine deaminase activity
BOQ57_RS11835	COG2233	PERMEase
BOQ57_RS11840	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BOQ57_RS11840	COG2080	2 iron, 2 sulfur cluster binding
BOQ57_RS11845	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BOQ57_RS11850	COG0402	S-adenosylhomocysteine deaminase activity
BOQ57_RS11855	COG0493	'glutamate synthase
BOQ57_RS11855	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BOQ57_RS11860	COG2068	MobA-Related Protein
BOQ57_RS11865	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BOQ57_RS11870	COG3608	succinylglutamate desuccinylase aspartoacylase
BOQ57_RS11870	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BOQ57_RS11875	COG0697	spore germination
BOQ57_RS11880	COG0549	Belongs to the carbamate kinase family
BOQ57_RS11890	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BOQ57_RS11895	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BOQ57_RS11900	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BOQ57_RS11905	COG3829	transcription factor binding
BOQ57_RS11930	COG1024	Enoyl-CoA hydratase
BOQ57_RS11930	COG1250	3-hydroxyacyl-CoA dehydrogenase
BOQ57_RS11935	COG0183	Belongs to the thiolase family
BOQ57_RS11940	COG0714	Associated with various cellular activities
BOQ57_RS11970	COG1595	DNA-templated transcription, initiation
BOQ57_RS11985	COG2067	long-chain fatty acid transport protein
BOQ57_RS11990	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BOQ57_RS12010	COG3123	guanosine phosphorylase activity
BOQ57_RS12015	COG1760	l-serine dehydratase
BOQ57_RS12025	COG1760	l-serine dehydratase
BOQ57_RS12030	COG2951	lytic endotransglycosylase activity
BOQ57_RS12035	COG3100	YcgL domain-containing protein
BOQ57_RS12040	COG0850	regulation of cytokinetic process
BOQ57_RS12045	COG2894	cell division
BOQ57_RS12050	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BOQ57_RS12055	COG3099	Belongs to the UPF0263 family
BOQ57_RS12060	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BOQ57_RS12100	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BOQ57_RS12105	COG0697	spore germination
BOQ57_RS12110	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BOQ57_RS12115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOQ57_RS12125	COG0307	riboflavin synthase, alpha
BOQ57_RS12135	COG0534	Mate efflux family protein
BOQ57_RS12165	COG0417	DNA replication proofreading
BOQ57_RS12190	COG1560	Kdo2-lipid A biosynthetic process
BOQ57_RS12195	COG1560	Kdo2-lipid A biosynthetic process
BOQ57_RS12205	COG0583	DNA-binding transcription factor activity
BOQ57_RS12210	COG0673	inositol 2-dehydrogenase activity
BOQ57_RS12215	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BOQ57_RS12220	COG0583	DNA-binding transcription factor activity
BOQ57_RS12230	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BOQ57_RS12240	COG5001	Diguanylate cyclase
BOQ57_RS12240	COG3300	MHYT domain
BOQ57_RS12245	COG2723	6-phospho-beta-galactosidase activity
BOQ57_RS12250	COG0583	DNA-binding transcription factor activity
BOQ57_RS12255	COG5001	Diguanylate cyclase
BOQ57_RS12255	COG3300	MHYT domain
BOQ57_RS12300	COG2003	Belongs to the UPF0758 family
BOQ57_RS12320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BOQ57_RS12335	COG0582	viral genome integration into host DNA
BOQ57_RS12345	COG0730	response to heat
BOQ57_RS12355	COG1028	Short-chain dehydrogenase reductase Sdr
BOQ57_RS12365	COG1024	Enoyl-CoA hydratase
BOQ57_RS12370	COG1024	Enoyl-CoA hydratase
BOQ57_RS12375	COG1960	acyl-CoA dehydrogenase activity
BOQ57_RS12385	COG1960	acyl-CoA dehydrogenase activity
BOQ57_RS12390	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BOQ57_RS12425	COG1584	GPR1 FUN34 yaaH family protein
BOQ57_RS12430	COG3228	Belongs to the MtfA family
BOQ57_RS12440	COG1115	amino acid carrier protein
BOQ57_RS12445	COG1024	Enoyl-CoA hydratase
BOQ57_RS12460	COG3162	membrane
BOQ57_RS12465	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BOQ57_RS12470	COG0488	(ABC) transporter
BOQ57_RS12475	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BOQ57_RS12480	COG0776	regulation of translation
BOQ57_RS12485	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BOQ57_RS12490	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BOQ57_RS12495	COG0740	serine-type endopeptidase activity
BOQ57_RS12500	COG0544	peptidyl-prolyl cis-trans isomerase activity
BOQ57_RS12515	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BOQ57_RS12520	COG4591	ABC-type transport system involved in lipoprotein release permease component
BOQ57_RS12525	COG1136	(ABC) transporter
BOQ57_RS12530	COG4591	ABC-type transport system involved in lipoprotein release permease component
BOQ57_RS12540	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BOQ57_RS12545	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BOQ57_RS12550	COG4166	transmembrane transport
BOQ57_RS12555	COG0697	spore germination
BOQ57_RS12565	COG2062	phosphohistidine phosphatase, SixA
BOQ57_RS12605	COG0519	Catalyzes the synthesis of GMP from XMP
BOQ57_RS12605	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BOQ57_RS12610	COG0516	GMP reductase activity
BOQ57_RS12610	COG0517	IMP dehydrogenase activity
BOQ57_RS12615	COG3158	transport of potassium into the cell
BOQ57_RS12635	COG0697	spore germination
BOQ57_RS12640	COG1570	exodeoxyribonuclease VII activity
BOQ57_RS12655	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BOQ57_RS12660	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BOQ57_RS12665	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BOQ57_RS12705	COG4771	TonB-dependent receptor
BOQ57_RS12710	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOQ57_RS12715	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BOQ57_RS12720	COG1120	ATPase activity
BOQ57_RS12730	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BOQ57_RS12735	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOQ57_RS12745	COG1028	Short-chain dehydrogenase reductase Sdr
BOQ57_RS12750	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BOQ57_RS12755	COG3433	isochorismatase activity
BOQ57_RS12755	COG1535	isochorismatase
BOQ57_RS12760	COG1021	2,3-dihydroxybenzoate-AMP ligase
BOQ57_RS12780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BOQ57_RS12785	COG3300	MHYT domain
BOQ57_RS12785	COG5001	Diguanylate cyclase
BOQ57_RS12800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOQ57_RS12810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BOQ57_RS12815	COG0563	adenylate kinase activity
BOQ57_RS12825	COG0326	Molecular chaperone. Has ATPase activity
BOQ57_RS12830	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BOQ57_RS12855	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BOQ57_RS12865	COG3158	transport of potassium into the cell
BOQ57_RS12870	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BOQ57_RS12875	COG0651	ATP synthesis coupled electron transport
BOQ57_RS12880	COG0650	Formate hydrogenlyase subunit 4
BOQ57_RS12885	COG3261	NADH dehydrogenase
BOQ57_RS12885	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BOQ57_RS12890	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOQ57_RS12895	COG3260	NADH ubiquinone oxidoreductase 20
BOQ57_RS12905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BOQ57_RS12910	COG1921	L-seryl-tRNASec selenium transferase activity
BOQ57_RS12920	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BOQ57_RS12925	COG0298	carbon dioxide binding
BOQ57_RS12935	COG0309	Hydrogenase expression formation protein (HypE)
BOQ57_RS12940	COG0375	protein maturation
BOQ57_RS12945	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BOQ57_RS12950	COG3842	ATPase activity
BOQ57_RS12960	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOQ57_RS12970	COG0747	negative chemotaxis
BOQ57_RS12975	COG1773	rubredoxin
BOQ57_RS12980	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BOQ57_RS12985	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BOQ57_RS12990	COG5557	Pfam Polysulphide reductase, NrfD
BOQ57_RS12995	COG0437	4 iron, 4 sulfur cluster binding
BOQ57_RS13000	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BOQ57_RS13015	COG2198	Histidine kinase
BOQ57_RS13015	COG0643	Histidine kinase
BOQ57_RS13020	COG3290	protein histidine kinase activity
BOQ57_RS13020	COG0840	transmembrane signaling receptor activity
BOQ57_RS13025	COG0835	chemotaxis
BOQ57_RS13035	COG2201	protein-glutamate methylesterase activity
BOQ57_RS13045	COG0840	transmembrane signaling receptor activity
BOQ57_RS13050	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BOQ57_RS13070	COG0659	secondary active sulfate transmembrane transporter activity
BOQ57_RS13100	COG0672	)-iron permease
BOQ57_RS13120	COG2814	Major facilitator Superfamily
BOQ57_RS13130	COG1136	(ABC) transporter
BOQ57_RS13135	COG0577	efflux transmembrane transporter activity
BOQ57_RS13165	COG1139	Iron-sulfur cluster binding protein
BOQ57_RS13170	COG0247	lactate metabolic process
BOQ57_RS13175	COG1620	l-lactate permease
BOQ57_RS13180	COG0583	DNA-binding transcription factor activity
BOQ57_RS13190	COG0346	lactoylglutathione lyase activity
BOQ57_RS13195	COG0596	Alpha beta hydrolase
BOQ57_RS13220	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BOQ57_RS13225	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BOQ57_RS13225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BOQ57_RS13230	COG0527	aspartate kinase activity
BOQ57_RS13245	COG1368	sulfuric ester hydrolase activity
BOQ57_RS13250	COG1619	proteins homologs of microcin C7 resistance protein MccF
BOQ57_RS13255	COG4667	esterase of the alpha-beta hydrolase superfamily
BOQ57_RS13275	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BOQ57_RS13275	COG1648	precorrin-2 dehydrogenase activity
BOQ57_RS13285	COG0393	Putative heavy-metal-binding
BOQ57_RS13305	COG1252	NADH dehydrogenase
BOQ57_RS13310	COG3150	esterase
BOQ57_RS13315	COG2233	PERMEase
BOQ57_RS13330	COG2354	Protein conserved in bacteria
BOQ57_RS13340	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOQ57_RS13345	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BOQ57_RS13380	COG0537	adenosine 5'-monophosphoramidase activity
BOQ57_RS13395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BOQ57_RS13410	COG1301	dicarboxylic acid transport
BOQ57_RS13420	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BOQ57_RS13425	COG0861	Integral membrane protein TerC family
BOQ57_RS13440	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOQ57_RS13445	COG0601	transmembrane transport
BOQ57_RS13455	COG2095	MarC family integral membrane protein
BOQ57_RS13465	COG1454	alcohol dehydrogenase
BOQ57_RS13465	COG1012	belongs to the aldehyde dehydrogenase family
BOQ57_RS13470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BOQ57_RS13470	COG2199	diguanylate cyclase activity
BOQ57_RS13475	COG3275	phosphorelay sensor kinase activity
BOQ57_RS13480	COG3279	Response regulator of the LytR AlgR family
BOQ57_RS13485	COG1966	Carbon starvation protein
BOQ57_RS13495	COG1566	PFAM secretion protein HlyD family protein
BOQ57_RS13500	COG1061	Type III restriction enzyme res subunit
BOQ57_RS13505	COG2027	D-alanyl-D-alanine carboxypeptidase
BOQ57_RS13510	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BOQ57_RS13520	COG0436	Aminotransferase
BOQ57_RS13525	COG1288	antiporter activity
BOQ57_RS13530	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BOQ57_RS13550	COG0697	spore germination
BOQ57_RS13555	COG4657	Part of a membrane complex involved in electron transport
BOQ57_RS13560	COG2878	Part of a membrane complex involved in electron transport
BOQ57_RS13570	COG4658	electron transport chain
BOQ57_RS13575	COG4659	FMN binding
BOQ57_RS13580	COG4660	Part of a membrane complex involved in electron transport
BOQ57_RS13585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BOQ57_RS13590	COG0346	lactoylglutathione lyase activity
BOQ57_RS13605	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BOQ57_RS13610	COG2056	Na+-H+ antiporter family
BOQ57_RS13620	COG2050	protein possibly involved in aromatic compounds catabolism
BOQ57_RS13630	COG0247	lactate metabolic process
BOQ57_RS13630	COG0277	FAD linked oxidase domain protein
BOQ57_RS13640	COG1253	flavin adenine dinucleotide binding
BOQ57_RS13645	COG1902	pentaerythritol trinitrate reductase activity
BOQ57_RS13655	COG0647	UMP catabolic process
BOQ57_RS13660	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BOQ57_RS13660	COG4651	solute:proton antiporter activity
BOQ57_RS13670	COG0367	asparagine synthase
BOQ57_RS13680	COG0625	glutathione transferase activity
BOQ57_RS13685	COG0625	glutathione transferase activity
BOQ57_RS13695	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BOQ57_RS13710	COG0564	pseudouridine synthase activity
BOQ57_RS13715	COG5001	Diguanylate cyclase
BOQ57_RS13720	COG0840	transmembrane signaling receptor activity
BOQ57_RS13730	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BOQ57_RS13730	COG0392	lysyltransferase activity
BOQ57_RS13740	COG2194	sulfuric ester hydrolase activity
BOQ57_RS13760	COG0670	Belongs to the BI1 family
BOQ57_RS13765	COG1289	transmembrane transporter activity
BOQ57_RS13770	COG2920	part of a sulfur-relay system
BOQ57_RS13775	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BOQ57_RS13780	COG0285	dihydrofolate synthase activity
BOQ57_RS13785	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BOQ57_RS13790	COG0101	tRNA pseudouridine synthase activity
BOQ57_RS13800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BOQ57_RS13805	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BOQ57_RS13810	COG0671	phosphoesterase, PA-phosphatase related
BOQ57_RS13815	COG1464	Belongs to the NlpA lipoprotein family
BOQ57_RS13855	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BOQ57_RS13855	COG0574	Belongs to the PEP-utilizing enzyme family
BOQ57_RS13860	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BOQ57_RS13955	COG1242	4 iron, 4 sulfur cluster binding
BOQ57_RS13965	COG0070	glutamate synthase
BOQ57_RS13965	COG0069	glutamate synthase activity
BOQ57_RS13965	COG0067	glutamate synthase
BOQ57_RS13970	COG0493	'glutamate synthase
BOQ57_RS13975	COG1126	abc transporter atp-binding protein
BOQ57_RS13980	COG0765	amino acid transport
BOQ57_RS13985	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS14000	COG0789	Transcriptional regulator
BOQ57_RS14015	COG4104	PAAR repeat-containing protein
BOQ57_RS14025	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS14030	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BOQ57_RS14060	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BOQ57_RS14065	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BOQ57_RS14070	COG0505	Belongs to the CarA family
BOQ57_RS14075	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BOQ57_RS14085	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BOQ57_RS14090	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BOQ57_RS14095	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BOQ57_RS14105	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BOQ57_RS14110	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BOQ57_RS14115	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BOQ57_RS14125	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BOQ57_RS14135	COG2205	protein histidine kinase activity
BOQ57_RS14135	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS14150	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BOQ57_RS14175	COG0023	Translation Initiation Factor
BOQ57_RS14180	COG2119	membrane
BOQ57_RS14210	COG2203	Gaf domain
BOQ57_RS14210	COG2199	diguanylate cyclase activity
BOQ57_RS14235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BOQ57_RS14245	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BOQ57_RS14250	COG3301	Polysulphide reductase, NrfD
BOQ57_RS14255	COG0437	4 iron, 4 sulfur cluster binding
BOQ57_RS14260	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BOQ57_RS14315	COG0322	excinuclease ABC activity
BOQ57_RS14320	COG2197	response regulator
BOQ57_RS14325	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BOQ57_RS14330	COG2835	tetraacyldisaccharide 4'-kinase activity
BOQ57_RS14335	COG1663	tetraacyldisaccharide 4'-kinase activity
BOQ57_RS14340	COG1132	(ABC) transporter
BOQ57_RS14345	COG2333	competence protein COMEC
BOQ57_RS14345	COG0658	competence protein
BOQ57_RS14360	COG0433	COG0433 Predicted ATPase
BOQ57_RS14365	COG1448	Aminotransferase
BOQ57_RS14380	COG1199	ATP-dependent helicase activity
BOQ57_RS14390	COG0123	including yeast histone deacetylase and acetoin utilization protein
BOQ57_RS14395	COG0477	Major facilitator Superfamily
BOQ57_RS14400	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BOQ57_RS14425	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BOQ57_RS14440	COG2271	Major facilitator Superfamily
BOQ57_RS14445	COG3706	GGDEF domain
BOQ57_RS14450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS14455	COG0765	amino acid transport
BOQ57_RS14460	COG1126	abc transporter atp-binding protein
BOQ57_RS14475	COG0531	amino acid
BOQ57_RS14490	COG1253	flavin adenine dinucleotide binding
BOQ57_RS14495	COG0704	Plays a role in the regulation of phosphate uptake
BOQ57_RS14500	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BOQ57_RS14505	COG0581	inorganic phosphate transmembrane transporter activity
BOQ57_RS14510	COG0573	inorganic phosphate transmembrane transporter activity
BOQ57_RS14515	COG0590	tRNA wobble adenosine to inosine editing
BOQ57_RS14525	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BOQ57_RS14545	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BOQ57_RS14550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BOQ57_RS14555	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BOQ57_RS14560	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BOQ57_RS14590	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BOQ57_RS14600	COG2239	Acts as a magnesium transporter
BOQ57_RS14610	COG1256	bacterial-type flagellum assembly
BOQ57_RS14620	COG1706	bacterial-type flagellum-dependent cell motility
BOQ57_RS14625	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BOQ57_RS14635	COG4787	bacterial-type flagellum-dependent cell motility
BOQ57_RS14640	COG1749	Flagellar hook protein flgE
BOQ57_RS14655	COG1815	bacterial-type flagellum-dependent cell motility
BOQ57_RS14660	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BOQ57_RS14665	COG0784	Response regulator, receiver
BOQ57_RS14665	COG0835	chemotaxis
BOQ57_RS14670	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BOQ57_RS14685	COG0622	Phosphoesterase
BOQ57_RS14715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BOQ57_RS14720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BOQ57_RS14725	COG1882	Formate acetyltransferase
BOQ57_RS14730	COG1349	DNA-binding transcription factor activity
BOQ57_RS14735	COG0697	spore germination
BOQ57_RS14765	COG1278	Cold shock
BOQ57_RS14805	COG3132	Protein of unknown function, DUF480
BOQ57_RS14820	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOQ57_RS14840	COG3206	protein involved in exopolysaccharide biosynthesis
BOQ57_RS14840	COG0489	protein tyrosine kinase activity
BOQ57_RS14850	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BOQ57_RS14860	COG1091	dTDP-4-dehydrorhamnose reductase activity
BOQ57_RS14875	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BOQ57_RS14900	COG1086	Polysaccharide biosynthesis protein
BOQ57_RS14910	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BOQ57_RS14915	COG0482	sulfurtransferase activity
BOQ57_RS14920	COG1216	Glycosyl transferase, family 2
BOQ57_RS14935	COG2826	transposase and inactivated derivatives, IS30 family
BOQ57_RS14985	COG1091	dTDP-4-dehydrorhamnose reductase activity
BOQ57_RS14995	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BOQ57_RS15000	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BOQ57_RS15015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOQ57_RS15020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS15025	COG1309	transcriptional regulator
BOQ57_RS15040	COG1946	Acyl-CoA thioesterase
BOQ57_RS15050	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BOQ57_RS15060	COG0009	L-threonylcarbamoyladenylate synthase
BOQ57_RS15070	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BOQ57_RS15075	COG0512	Glutamine amidotransferase of anthranilate synthase
BOQ57_RS15075	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BOQ57_RS15080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BOQ57_RS15085	COG0134	indole-3-glycerol-phosphate synthase activity
BOQ57_RS15085	COG0135	phosphoribosylanthranilate isomerase activity
BOQ57_RS15090	COG0133	tryptophan synthase activity
BOQ57_RS15095	COG0159	tryptophan synthase activity
BOQ57_RS15100	COG1988	membrane-bound metal-dependent
BOQ57_RS15120	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BOQ57_RS15130	COG4521	taurine ABC transporter
BOQ57_RS15135	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BOQ57_RS15140	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOQ57_RS15145	COG2175	clavaminate synthase activity
BOQ57_RS15155	COG2814	Major facilitator Superfamily
BOQ57_RS15160	COG0109	protoheme IX farnesyltransferase activity
BOQ57_RS15165	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BOQ57_RS15170	COG1845	cytochrome c oxidase, subunit III
BOQ57_RS15175	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BOQ57_RS15180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BOQ57_RS15225	COG2211	Major facilitator Superfamily
BOQ57_RS15240	COG0708	Exodeoxyribonuclease III
BOQ57_RS15260	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS15265	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOQ57_RS15285	COG0095	Lipoate-protein ligase
BOQ57_RS15315	COG0640	Transcriptional regulator
BOQ57_RS15330	COG1285	pathogenesis
BOQ57_RS15360	COG0484	heat shock protein binding
BOQ57_RS15365	COG0443	Heat shock 70 kDa protein
BOQ57_RS15370	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BOQ57_RS15375	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BOQ57_RS15380	COG0497	DNA recombination
BOQ57_RS15385	COG1227	inorganic diphosphatase activity
BOQ57_RS15395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS15400	COG1136	(ABC) transporter
BOQ57_RS15400	COG0577	efflux transmembrane transporter activity
BOQ57_RS15410	COG2375	cellular response to nickel ion
BOQ57_RS15420	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BOQ57_RS15440	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BOQ57_RS15445	COG1396	sequence-specific DNA binding
BOQ57_RS15445	COG1917	Cupin 2, conserved barrel domain protein
BOQ57_RS15460	COG0531	amino acid
BOQ57_RS15470	COG0531	amino acid
BOQ57_RS15480	COG1283	sodium-dependent phosphate transmembrane transporter activity
BOQ57_RS15490	COG3384	dioxygenase
BOQ57_RS15495	COG2205	protein histidine kinase activity
BOQ57_RS15495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS15510	COG0813	purine-nucleoside phosphorylase activity
BOQ57_RS15530	COG0488	(ABC) transporter
BOQ57_RS15545	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BOQ57_RS15550	COG0083	homoserine kinase activity
BOQ57_RS15560	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BOQ57_RS15565	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BOQ57_RS15580	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BOQ57_RS15590	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS15605	COG4988	ABC transporter
BOQ57_RS15610	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BOQ57_RS15630	COG1720	tRNA m6t6A37 methyltransferase activity
BOQ57_RS15645	COG0542	response to heat
BOQ57_RS15650	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BOQ57_RS15655	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS15665	COG2190	(PTS) system
BOQ57_RS15680	COG3038	cytochrome b561
BOQ57_RS15690	COG0420	3'-5' exonuclease activity
BOQ57_RS15700	COG2974	May be involved in recombination
BOQ57_RS15710	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BOQ57_RS15710	COG4651	solute:proton antiporter activity
BOQ57_RS15725	COG0469	pyruvate kinase activity
BOQ57_RS15730	COG3264	Mechanosensitive ion channel
BOQ57_RS15730	COG1196	nuclear chromosome segregation
BOQ57_RS15740	COG2706	6-phosphogluconolactonase activity
BOQ57_RS15760	COG0281	malic enzyme
BOQ57_RS15775	COG0437	4 iron, 4 sulfur cluster binding
BOQ57_RS15780	COG3383	formate dehydrogenase (NAD+) activity
BOQ57_RS15780	COG3383	formate dehydrogenase (NAD+) activity
BOQ57_RS15820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BOQ57_RS15825	COG1910	domain protein
BOQ57_RS15830	COG3852	Histidine kinase
BOQ57_RS15845	COG4662	Binding-protein-dependent transport system inner membrane component
BOQ57_RS15855	COG0746	molybdenum cofactor guanylyltransferase activity
BOQ57_RS15860	COG0303	'Molybdopterin
BOQ57_RS15865	COG1289	transmembrane transporter activity
BOQ57_RS15895	COG3220	belongs to the UPF0276 family
BOQ57_RS15925	COG0784	Response regulator, receiver
BOQ57_RS15925	COG2205	protein histidine kinase activity
BOQ57_RS15930	COG4166	transmembrane transport
BOQ57_RS15935	COG0601	transmembrane transport
BOQ57_RS15940	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BOQ57_RS15945	COG0444	Belongs to the ABC transporter superfamily
BOQ57_RS15950	COG4608	Belongs to the ABC transporter superfamily
BOQ57_RS15960	COG2971	BadF BadG BcrA BcrD
BOQ57_RS15970	COG0840	transmembrane signaling receptor activity
BOQ57_RS15985	COG3724	N-succinylarginine dihydrolase activity
BOQ57_RS15990	COG0616	signal peptide processing
BOQ57_RS15995	COG1028	Short-chain dehydrogenase reductase Sdr
BOQ57_RS16000	COG0583	DNA-binding transcription factor activity
BOQ57_RS16010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BOQ57_RS16020	COG0583	DNA-binding transcription factor activity
BOQ57_RS16025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BOQ57_RS16030	COG1881	PFAM PEBP family protein
BOQ57_RS16040	COG3408	Glycogen debranching enzyme
BOQ57_RS16040	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BOQ57_RS16045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BOQ57_RS16050	COG0739	heme binding
BOQ57_RS16055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BOQ57_RS16075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BOQ57_RS16085	COG3091	SprT-like family
BOQ57_RS16095	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BOQ57_RS16100	COG0189	ligase activity
BOQ57_RS16110	COG1678	Uncharacterized ACR, COG1678
BOQ57_RS16115	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BOQ57_RS16120	COG3104	oligopeptide transport
BOQ57_RS16145	COG0714	Associated with various cellular activities
BOQ57_RS16160	COG1115	amino acid carrier protein
BOQ57_RS16165	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BOQ57_RS16180	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BOQ57_RS16190	COG1301	dicarboxylic acid transport
BOQ57_RS16195	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BOQ57_RS16200	COG2912	Transglutaminase-like superfamily
BOQ57_RS16210	COG2890	protein-(glutamine-N5) methyltransferase activity
BOQ57_RS16215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BOQ57_RS16220	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BOQ57_RS16225	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BOQ57_RS16230	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BOQ57_RS16240	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BOQ57_RS16245	COG0737	Belongs to the 5'-nucleotidase family
BOQ57_RS16250	COG0193	aminoacyl-tRNA hydrolase activity
BOQ57_RS16255	COG0012	GTP binding
BOQ57_RS16300	COG0490	domain, Protein
BOQ57_RS16300	COG0471	metal ion transport
BOQ57_RS16330	COG0366	Alpha amylase catalytic
BOQ57_RS16345	COG0488	(ABC) transporter
BOQ57_RS16355	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BOQ57_RS16355	COG0674	pyruvate-flavodoxin oxidoreductase activity
BOQ57_RS16355	COG1013	pyruvate-flavodoxin oxidoreductase activity
BOQ57_RS16355	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BOQ57_RS16365	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOQ57_RS16375	COG1012	belongs to the aldehyde dehydrogenase family
BOQ57_RS16385	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BOQ57_RS16400	COG0180	Tryptophanyl-tRNA synthetase
BOQ57_RS16410	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BOQ57_RS16415	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BOQ57_RS16425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BOQ57_RS16430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BOQ57_RS16460	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BOQ57_RS16465	COG0583	DNA-binding transcription factor activity
BOQ57_RS16485	COG0583	DNA-binding transcription factor activity
BOQ57_RS16510	COG1511	domain protein
BOQ57_RS16510	COG3264	Mechanosensitive ion channel
BOQ57_RS16515	COG0584	glycerophosphoryl diester phosphodiesterase
BOQ57_RS16525	COG1053	succinate dehydrogenase
BOQ57_RS16530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BOQ57_RS16535	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BOQ57_RS16560	COG3214	Protein conserved in bacteria
BOQ57_RS16600	COG0642	Histidine kinase
BOQ57_RS16610	COG0516	GMP reductase activity
BOQ57_RS16620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BOQ57_RS16625	COG3647	Membrane
BOQ57_RS16635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BOQ57_RS16655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOQ57_RS16670	COG3706	GGDEF domain
BOQ57_RS16680	COG1335	isochorismatase
BOQ57_RS16685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BOQ57_RS16690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BOQ57_RS16695	COG1702	phosphate starvation-inducible protein PhoH
BOQ57_RS16700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BOQ57_RS16705	COG4535	Mg2 and Co2 transporter CorC
BOQ57_RS16710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BOQ57_RS16715	COG2888	peptidyl-tyrosine sulfation
BOQ57_RS16720	COG0495	leucyl-tRNA aminoacylation
BOQ57_RS16735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BOQ57_RS16740	COG0799	negative regulation of ribosome biogenesis
BOQ57_RS16745	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BOQ57_RS16750	COG0768	penicillin binding
BOQ57_RS16755	COG0772	Belongs to the SEDS family
BOQ57_RS16760	COG0772	Belongs to the SEDS family
BOQ57_RS16765	COG2951	lytic endotransglycosylase activity
BOQ57_RS16770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BOQ57_RS16775	COG1686	Belongs to the peptidase S11 family
BOQ57_RS16780	COG2921	Belongs to the UPF0250 family
BOQ57_RS16785	COG0321	lipoyl(octanoyl) transferase activity
BOQ57_RS16795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BOQ57_RS16805	COG3545	Serine hydrolase
BOQ57_RS16810	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BOQ57_RS16825	COG0789	Transcriptional regulator
BOQ57_RS16835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BOQ57_RS16840	COG1970	mechanosensitive ion channel activity
BOQ57_RS16850	COG4974	Belongs to the 'phage' integrase family
BOQ57_RS16860	COG0312	modulator of DNA gyrase
BOQ57_RS16865	COG0312	modulator of DNA gyrase
BOQ57_RS16930	COG3275	phosphorelay sensor kinase activity
BOQ57_RS16935	COG3279	Response regulator of the LytR AlgR family
BOQ57_RS16940	COG1966	Carbon starvation protein
BOQ57_RS16950	COG0114	fumarate hydratase activity
BOQ57_RS16960	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BOQ57_RS16970	COG2211	Major facilitator Superfamily
BOQ57_RS16975	COG1185	polyribonucleotide nucleotidyltransferase activity
BOQ57_RS16980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BOQ57_RS16985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BOQ57_RS16990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BOQ57_RS16995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BOQ57_RS17000	COG0195	Participates in both transcription termination and antitermination
BOQ57_RS17005	COG0779	Required for maturation of 30S ribosomal subunits
BOQ57_RS17020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BOQ57_RS17025	COG0149	triose-phosphate isomerase activity
BOQ57_RS17030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BOQ57_RS17035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BOQ57_RS17045	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BOQ57_RS17050	COG1534	Rna-binding protein
BOQ57_RS17065	COG1360	Flagellar Motor Protein
BOQ57_RS17070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BOQ57_RS17080	COG0142	geranyltranstransferase activity
BOQ57_RS17085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BOQ57_RS17095	COG0601	transmembrane transport
BOQ57_RS17105	COG4172	Belongs to the ABC transporter superfamily
BOQ57_RS17110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BOQ57_RS17115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BOQ57_RS17120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BOQ57_RS17125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BOQ57_RS17145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOQ57_RS17145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BOQ57_RS17150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BOQ57_RS17160	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BOQ57_RS17175	COG3381	protein complex oligomerization
BOQ57_RS17195	COG5001	Diguanylate cyclase
BOQ57_RS17195	COG3300	MHYT domain
BOQ57_RS17205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BOQ57_RS17210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BOQ57_RS17215	COG0511	ligase activity, forming carbon-carbon bonds
BOQ57_RS17220	COG0439	Biotin carboxylase
BOQ57_RS17230	COG4145	pantothenate transmembrane transporter activity
BOQ57_RS17235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS17235	COG2190	(PTS) system
BOQ57_RS17235	COG1263	PTS System
BOQ57_RS17240	COG0583	DNA-binding transcription factor activity
BOQ57_RS17245	COG0604	alcohol dehydrogenase
BOQ57_RS17250	COG2264	protein methyltransferase activity
BOQ57_RS17275	COG0778	Nitroreductase
BOQ57_RS17280	COG1902	pentaerythritol trinitrate reductase activity
BOQ57_RS17280	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOQ57_RS17285	COG0616	signal peptide processing
BOQ57_RS17305	COG3139	Protein of unknown function (DUF1315)
BOQ57_RS17310	COG0252	asparaginase activity
BOQ57_RS17315	COG0786	glutamate:sodium symporter activity
BOQ57_RS17330	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BOQ57_RS17335	COG0384	phenazine biosynthesis protein PhzF
BOQ57_RS17340	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BOQ57_RS17345	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOQ57_RS17350	COG0175	sulfate reduction
BOQ57_RS17355	COG2113	Glycine betaine
BOQ57_RS17360	COG4176	ABC-type proline glycine betaine transport system permease component
BOQ57_RS17365	COG4175	Glycine betaine
BOQ57_RS17375	COG3610	response to peptide
BOQ57_RS17380	COG2966	Psort location CytoplasmicMembrane, score
BOQ57_RS17390	COG0521	Mo-molybdopterin cofactor biosynthetic process
BOQ57_RS17400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BOQ57_RS17405	COG1028	Short-chain dehydrogenase reductase Sdr
BOQ57_RS17450	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BOQ57_RS17465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOQ57_RS17470	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BOQ57_RS17505	COG1858	cytochrome C peroxidase
BOQ57_RS17515	COG2313	pseudouridylate synthase activity
BOQ57_RS17520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BOQ57_RS17525	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOQ57_RS17525	COG2146	nitrite reductase [NAD(P)H] activity
BOQ57_RS17530	COG2146	nitrite reductase [NAD(P)H] activity
BOQ57_RS17530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOQ57_RS17535	COG1116	anion transmembrane transporter activity
BOQ57_RS17540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BOQ57_RS17545	COG1116	anion transmembrane transporter activity
BOQ57_RS17545	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BOQ57_RS17560	COG0243	molybdopterin cofactor binding
BOQ57_RS17585	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BOQ57_RS17600	COG1073	alpha beta
BOQ57_RS17605	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BOQ57_RS17615	COG2195	Cleaves the N-terminal amino acid of tripeptides
BOQ57_RS17625	COG4608	Belongs to the ABC transporter superfamily
BOQ57_RS17630	COG0444	Belongs to the ABC transporter superfamily
BOQ57_RS17640	COG4239	(ABC) transporter, permease
BOQ57_RS17645	COG4174	ABC transporter (Permease)
BOQ57_RS17660	COG0811	peptide transport
BOQ57_RS17665	COG0811	peptide transport
BOQ57_RS17670	COG0848	biopolymer transport protein
BOQ57_RS17720	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOQ57_RS17725	COG0840	transmembrane signaling receptor activity
BOQ57_RS17735	COG1278	Cold shock
BOQ57_RS17775	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BOQ57_RS17780	COG1162	GTPase activity
BOQ57_RS17785	COG0688	phosphatidylethanolamine metabolic process
BOQ57_RS17790	COG4628	conserved protein (DUF2132)
BOQ57_RS17805	COG3059	membrane
BOQ57_RS17810	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BOQ57_RS17815	COG2207	Transcriptional regulator
BOQ57_RS17825	COG5001	Diguanylate cyclase
BOQ57_RS17825	COG3300	MHYT domain
BOQ57_RS17830	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BOQ57_RS17850	COG2203	Gaf domain
BOQ57_RS17850	COG3706	GGDEF domain
BOQ57_RS17850	COG4251	negative regulation of phosphorylation
BOQ57_RS17850	COG5001	Diguanylate cyclase
BOQ57_RS17860	COG3039	Transposase
BOQ57_RS17910	COG4974	Belongs to the 'phage' integrase family
BOQ57_RS17925	COG0582	viral genome integration into host DNA
BOQ57_RS17950	COG1132	(ABC) transporter
BOQ57_RS17960	COG2897	thiosulfate sulfurtransferase activity
BOQ57_RS17965	COG2066	Belongs to the glutaminase family
BOQ57_RS17970	COG3171	Protein conserved in bacteria
BOQ57_RS17975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BOQ57_RS17980	COG2234	aminopeptidase activity
BOQ57_RS17980	COG4935	Belongs to the peptidase S8 family
BOQ57_RS17985	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOQ57_RS17990	COG2200	EAL domain
BOQ57_RS17995	COG1090	epimerase
BOQ57_RS18000	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BOQ57_RS18005	COG4181	ATPase activity
BOQ57_RS18010	COG2755	lipolytic protein G-D-S-L family
BOQ57_RS18015	COG0784	Response regulator, receiver
BOQ57_RS18015	COG0835	chemotaxis
BOQ57_RS18200	COG0569	domain protein
BOQ57_RS18200	COG2985	domain, Protein
BOQ57_RS18205	COG1272	protein, Hemolysin III
BOQ57_RS18210	COG0076	glutamate decarboxylase activity
BOQ57_RS18215	COG2917	probably involved in intracellular septation
BOQ57_RS18220	COG2350	Protein conserved in bacteria
BOQ57_RS18230	COG1555	photosystem II stabilization
BOQ57_RS18235	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BOQ57_RS18240	COG3104	oligopeptide transport
BOQ57_RS18245	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS18275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS18290	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BOQ57_RS18305	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BOQ57_RS18320	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BOQ57_RS18370	COG2003	Belongs to the UPF0758 family
BOQ57_RS18395	COG1484	DNA-dependent DNA replication
BOQ57_RS18400	COG4584	PFAM Integrase catalytic
BOQ57_RS18425	COG3311	Transcriptional regulator
BOQ57_RS18445	COG1280	lysine exporter protein (LysE YggA)
BOQ57_RS18470	COG0316	Belongs to the HesB IscA family
BOQ57_RS18480	COG0038	chloride channel
BOQ57_RS18485	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BOQ57_RS18500	COG0671	phosphoesterase, PA-phosphatase related
BOQ57_RS18510	COG0784	Response regulator, receiver
BOQ57_RS18510	COG3437	response regulator, receiver
BOQ57_RS18520	COG2076	Multidrug Resistance protein
BOQ57_RS18530	COG0346	lactoylglutathione lyase activity
BOQ57_RS18535	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BOQ57_RS18540	COG1643	Atp-dependent helicase
BOQ57_RS18550	COG1489	DNA binding
BOQ57_RS18555	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BOQ57_RS18560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BOQ57_RS18575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BOQ57_RS18580	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BOQ57_RS18600	COG1924	4 iron, 4 sulfur cluster binding
BOQ57_RS18605	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BOQ57_RS18610	COG0842	Transport permease protein
BOQ57_RS18615	COG1131	(ABC) transporter
BOQ57_RS18630	COG0163	prenyltransferase activity
BOQ57_RS18635	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BOQ57_RS18640	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BOQ57_RS18655	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BOQ57_RS18670	COG1136	(ABC) transporter
BOQ57_RS18690	COG0840	transmembrane signaling receptor activity
BOQ57_RS18715	COG0529	Catalyzes the synthesis of activated sulfate
BOQ57_RS18720	COG3273	potassium ion transport
BOQ57_RS18720	COG0471	metal ion transport
BOQ57_RS18725	COG2895	sulfate adenylyltransferase (ATP) activity
BOQ57_RS18730	COG0175	sulfate reduction
BOQ57_RS18735	COG1648	precorrin-2 dehydrogenase activity
BOQ57_RS18735	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BOQ57_RS18740	COG0330	HflC and HflK could
BOQ57_RS18745	COG1585	Membrane protein implicated in regulation of membrane protease activity
BOQ57_RS18750	COG0517	IMP dehydrogenase activity
BOQ57_RS18750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BOQ57_RS18755	COG0488	(ABC) transporter
BOQ57_RS18765	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BOQ57_RS18770	COG0583	DNA-binding transcription factor activity
BOQ57_RS18805	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BOQ57_RS18815	COG0668	transmembrane transport
BOQ57_RS18825	COG2731	YhcH YjgK YiaL family protein
BOQ57_RS18840	COG1794	racemase activity, acting on amino acids and derivatives
BOQ57_RS18880	COG0733	neurotransmitter:sodium symporter activity
BOQ57_RS18890	COG0733	neurotransmitter:sodium symporter activity
BOQ57_RS18905	COG0561	phosphatase activity
BOQ57_RS18935	COG1846	Transcriptional regulator
BOQ57_RS18940	COG1764	response to oxidative stress
BOQ57_RS18945	COG2130	NADP-dependent
BOQ57_RS18950	COG1051	belongs to the nudix hydrolase family
BOQ57_RS18970	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BOQ57_RS18975	COG1640	4-alpha-glucanotransferase
BOQ57_RS18980	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BOQ57_RS18985	COG0676	glucose-6-phosphate 1-epimerase activity
BOQ57_RS18990	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BOQ57_RS18995	COG0840	transmembrane signaling receptor activity
BOQ57_RS19070	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BOQ57_RS19075	COG2885	chlorophyll binding
BOQ57_RS19080	COG0823	Involved in the tonB-independent uptake of proteins
BOQ57_RS19095	COG0811	peptide transport
BOQ57_RS19100	COG0824	Thioesterase
BOQ57_RS19105	COG3790	cyd operon protein YbgE
BOQ57_RS19110	COG4890	Cyd operon protein YbgT
BOQ57_RS19115	COG1294	oxidase, subunit
BOQ57_RS19120	COG1271	oxidase subunit
BOQ57_RS19125	COG2255	four-way junction helicase activity
BOQ57_RS19130	COG0632	four-way junction helicase activity
BOQ57_RS19135	COG0840	transmembrane signaling receptor activity
BOQ57_RS19140	COG0442	prolyl-tRNA aminoacylation
BOQ57_RS19145	COG4221	oxidoreductase activity
BOQ57_RS19160	COG1024	Enoyl-CoA hydratase
BOQ57_RS19180	COG4166	transmembrane transport
BOQ57_RS19195	COG1872	DUF167
BOQ57_RS19200	COG0762	integral membrane protein
BOQ57_RS19205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BOQ57_RS19210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BOQ57_RS19225	COG3022	response to hydroperoxide
BOQ57_RS19230	COG0513	Belongs to the DEAD box helicase family
BOQ57_RS19235	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BOQ57_RS19260	COG0735	belongs to the Fur family
BOQ57_RS19265	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BOQ57_RS19280	COG0776	regulation of translation
BOQ57_RS19285	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BOQ57_RS19310	COG0560	Phosphoserine phosphatase
BOQ57_RS19320	COG5002	protein histidine kinase activity
BOQ57_RS19320	COG3447	MASE1 domain protein
BOQ57_RS19320	COG5001	Diguanylate cyclase
BOQ57_RS19325	COG0813	purine-nucleoside phosphorylase activity
BOQ57_RS19330	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BOQ57_RS19335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BOQ57_RS19340	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BOQ57_RS19350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BOQ57_RS19355	COG0084	hydrolase, TatD family'
BOQ57_RS19360	COG2165	general secretion pathway protein
BOQ57_RS19370	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BOQ57_RS19375	COG0004	ammonium transporteR
BOQ57_RS19385	COG1196	nuclear chromosome segregation
BOQ57_RS19415	COG0582	viral genome integration into host DNA
BOQ57_RS19430	COG0795	lipopolysaccharide-transporting ATPase activity
BOQ57_RS19435	COG0795	lipopolysaccharide-transporting ATPase activity
BOQ57_RS19440	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BOQ57_RS19445	COG2927	DNA polymerase III (CHI subunit)
BOQ57_RS19450	COG0525	valine-tRNA ligase activity
BOQ57_RS19455	COG1253	flavin adenine dinucleotide binding
BOQ57_RS19460	COG0586	Pfam SNARE associated Golgi protein
BOQ57_RS19465	COG1686	Belongs to the peptidase S11 family
BOQ57_RS19505	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BOQ57_RS19510	COG0527	aspartate kinase activity
BOQ57_RS19515	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BOQ57_RS19525	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BOQ57_RS19530	COG1546	Belongs to the CinA family
BOQ57_RS19535	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BOQ57_RS19555	COG3068	Protein conserved in bacteria
BOQ57_RS19565	COG0739	heme binding
BOQ57_RS19585	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BOQ57_RS19590	COG1121	(ABC) transporter
BOQ57_RS19595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BOQ57_RS19600	COG0583	DNA-binding transcription factor activity
BOQ57_RS19605	COG0697	spore germination
BOQ57_RS19610	COG1573	uracil-dna glycosylase
BOQ57_RS19615	COG2962	Rard protein
BOQ57_RS19625	COG2827	Endonuclease containing a URI domain
BOQ57_RS19640	COG1842	Phage shock protein A
BOQ57_RS19645	COG0204	Acyl-transferase
BOQ57_RS19670	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BOQ57_RS19710	COG0583	DNA-binding transcription factor activity
BOQ57_RS19725	COG0187	DNA topoisomerase II activity
BOQ57_RS19730	COG1289	transmembrane transporter activity
BOQ57_RS19735	COG1566	PFAM secretion protein HlyD family protein
BOQ57_RS19750	COG1051	belongs to the nudix hydrolase family
BOQ57_RS19755	COG3150	esterase
BOQ57_RS19765	COG3151	Protein conserved in bacteria
BOQ57_RS19770	COG0494	nUDIX hydrolase
BOQ57_RS19775	COG1538	Outer membrane efflux protein
BOQ57_RS19780	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BOQ57_RS19780	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BOQ57_RS19785	COG1560	Kdo2-lipid A biosynthetic process
BOQ57_RS19800	COG1392	Phosphate transport regulator
BOQ57_RS19805	COG0306	phosphate transporter
BOQ57_RS19810	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BOQ57_RS19840	COG0583	DNA-binding transcription factor activity
BOQ57_RS19845	COG1380	Effector of murein hydrolase LrgA
BOQ57_RS19850	COG1346	cytolysis
BOQ57_RS19865	COG0617	tRNA 3'-terminal CCA addition
BOQ57_RS19870	COG3409	Peptidoglycan-binding domain 1 protein
BOQ57_RS19870	COG3267	Type II secretory pathway component ExeA
BOQ57_RS19880	COG1194	a g-specific adenine glycosylase
BOQ57_RS19885	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BOQ57_RS19895	COG3111	PFAM Bacterial OB fold (BOF) protein
BOQ57_RS19900	COG3240	lipase activity
BOQ57_RS19910	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BOQ57_RS19910	COG2885	chlorophyll binding
BOQ57_RS19915	COG3009	Protein conserved in bacteria
BOQ57_RS19920	COG3008	intermembrane lipid transfer
BOQ57_RS19920	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BOQ57_RS19925	COG2995	paraquat-inducible protein a
BOQ57_RS19935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BOQ57_RS19945	COG4251	negative regulation of phosphorylation
BOQ57_RS19945	COG5001	Diguanylate cyclase
BOQ57_RS19945	COG3706	GGDEF domain
BOQ57_RS19945	COG2203	Gaf domain
BOQ57_RS19950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BOQ57_RS19955	COG2813	Specifically methylates the guanine in position
BOQ57_RS19960	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BOQ57_RS19965	COG0297	glycogen (starch) synthase activity
BOQ57_RS20005	COG1757	Na H antiporter
BOQ57_RS20010	COG0583	DNA-binding transcription factor activity
BOQ57_RS20015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BOQ57_RS20020	COG3842	ATPase activity
BOQ57_RS20025	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOQ57_RS20030	COG1177	transmembrane transport
BOQ57_RS20035	COG1012	belongs to the aldehyde dehydrogenase family
BOQ57_RS20045	COG5006	permease, DMT superfamily
BOQ57_RS20050	COG1522	sequence-specific DNA binding
BOQ57_RS20055	COG0110	maltose O-acetyltransferase activity
BOQ57_RS20060	COG0366	Alpha amylase catalytic
BOQ57_RS20065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BOQ57_RS20065	COG1263	PTS System
BOQ57_RS20085	COG0252	asparaginase activity
BOQ57_RS20100	COG1803	Methylglyoxal synthase
BOQ57_RS20125	COG1444	tRNA N-acetyltransferase activity
BOQ57_RS20135	COG0835	chemotaxis
BOQ57_RS20135	COG0784	Response regulator, receiver
BOQ57_RS20180	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BOQ57_RS20185	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BOQ57_RS20200	COG0477	Major facilitator Superfamily
BOQ57_RS20205	COG0523	cobalamin synthesis protein
BOQ57_RS20215	COG1280	lysine exporter protein (LysE YggA)
BOQ57_RS20225	COG2200	EAL domain
BOQ57_RS20230	COG1049	propionate catabolic process, 2-methylcitrate cycle
BOQ57_RS20235	COG1752	Esterase of the alpha-beta hydrolase superfamily
BOQ57_RS20240	COG0840	transmembrane signaling receptor activity
BOQ57_RS20245	COG0840	transmembrane signaling receptor activity
BOQ57_RS20255	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BOQ57_RS20260	COG0508	dehydrogenase complex catalyzes the overall conversion of
BOQ57_RS20265	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BOQ57_RS20270	COG2186	Transcriptional regulator
BOQ57_RS20300	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BOQ57_RS20305	COG1459	type II secretion system
BOQ57_RS20320	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BOQ57_RS20325	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BOQ57_RS20330	COG0494	nUDIX hydrolase
BOQ57_RS20340	COG0653	protein targeting
BOQ57_RS20350	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BOQ57_RS20355	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BOQ57_RS20360	COG0849	cell division
BOQ57_RS20365	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BOQ57_RS20370	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BOQ57_RS20375	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BOQ57_RS20380	COG0772	Belongs to the SEDS family
BOQ57_RS20385	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BOQ57_RS20390	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BOQ57_RS20395	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BOQ57_RS20405	COG0768	penicillin binding
BOQ57_RS20410	COG3116	cell division
BOQ57_RS20415	COG0275	rRNA processing
BOQ57_RS20420	COG2001	Belongs to the MraZ family
BOQ57_RS20430	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BOQ57_RS20435	COG3107	peptidoglycan biosynthetic process
BOQ57_RS20440	COG0792	nuclease activity
BOQ57_RS20445	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BOQ57_RS20450	COG2823	Periplasmic or secreted lipoprotein
BOQ57_RS20455	COG2969	positive regulation of protein catabolic process
BOQ57_RS20460	COG0625	glutathione transferase activity
BOQ57_RS20465	COG2857	Cytochrome c1
BOQ57_RS20470	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BOQ57_RS20475	COG0723	plastoquinol--plastocyanin reductase activity
BOQ57_RS20480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BOQ57_RS20485	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BOQ57_RS20490	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BOQ57_RS20500	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOQ57_RS20505	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BOQ57_RS20535	COG3964	amidohydrolase
BOQ57_RS20550	COG3711	transcriptional antiterminator
BOQ57_RS20550	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS20555	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS20560	COG1660	Displays ATPase and GTPase activities
BOQ57_RS20565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BOQ57_RS20575	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BOQ57_RS20580	COG1137	ATPase activity
BOQ57_RS20585	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BOQ57_RS20590	COG3117	lipopolysaccharide transmembrane transporter activity
BOQ57_RS20595	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BOQ57_RS20600	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BOQ57_RS20600	COG0517	IMP dehydrogenase activity
BOQ57_RS20605	COG1127	ABC transporter
BOQ57_RS20610	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BOQ57_RS20615	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BOQ57_RS20620	COG2854	intermembrane phospholipid transfer
BOQ57_RS20630	COG5007	Belongs to the BolA IbaG family
BOQ57_RS20635	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BOQ57_RS20640	COG0312	modulator of DNA gyrase
BOQ57_RS20645	COG3028	Belongs to the UPF0307 family
BOQ57_RS20655	COG2926	Belongs to the UPF0265 family
BOQ57_RS20685	COG1396	sequence-specific DNA binding
BOQ57_RS20690	COG3135	benzoate transporter
BOQ57_RS20715	COG0840	transmembrane signaling receptor activity
BOQ57_RS20720	COG3047	cAMP biosynthetic process
BOQ57_RS20730	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BOQ57_RS20735	COG2197	response regulator
BOQ57_RS20740	COG0629	single-stranded DNA binding
BOQ57_RS20765	COG1278	Cold shock
BOQ57_RS20775	COG4771	TonB-dependent receptor
BOQ57_RS20780	COG4251	negative regulation of phosphorylation
BOQ57_RS20780	COG3706	GGDEF domain
BOQ57_RS20780	COG2203	Gaf domain
BOQ57_RS20780	COG5001	Diguanylate cyclase
BOQ57_RS20825	COG0346	lactoylglutathione lyase activity
BOQ57_RS20835	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BOQ57_RS20840	COG1074	ATP-dependent DNA helicase activity
BOQ57_RS20845	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BOQ57_RS20850	COG2259	Doxx family
BOQ57_RS20855	COG1741	Belongs to the pirin family
BOQ57_RS20865	COG0583	DNA-binding transcription factor activity
BOQ57_RS20890	COG1175	transmembrane transport
BOQ57_RS20900	COG3842	ATPase activity
BOQ57_RS20910	COG2199	diguanylate cyclase activity
BOQ57_RS20910	COG2203	Gaf domain
BOQ57_RS20930	COG1247	-acetyltransferase
BOQ57_RS20935	COG0753	catalase activity
BOQ57_RS20960	COG0494	nUDIX hydrolase
BOQ57_RS20965	COG0628	permease
BOQ57_RS20980	COG2957	Belongs to the agmatine deiminase family
BOQ57_RS20985	COG0583	DNA-binding transcription factor activity
BOQ57_RS20990	COG3284	Transcriptional regulator
BOQ57_RS21005	COG1461	Dihydroxyacetone kinase
BOQ57_RS21010	COG2376	Dihydroxyacetone kinase
BOQ57_RS21015	COG2252	PERMEase
BOQ57_RS21050	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BOQ57_RS21055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BOQ57_RS21060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BOQ57_RS21065	COG0049	tRNA binding
BOQ57_RS21070	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BOQ57_RS21075	COG2168	tRNA wobble position uridine thiolation
BOQ57_RS21080	COG2923	Belongs to the DsrF TusC family
BOQ57_RS21090	COG0251	oxidation-reduction process
BOQ57_RS21095	COG2964	Protein conserved in bacteria
BOQ57_RS21100	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BOQ57_RS21105	COG0085	RNA polymerase activity
BOQ57_RS21110	COG0222	ribosome binding
BOQ57_RS21115	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BOQ57_RS21120	COG0081	regulation of translation
BOQ57_RS21125	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BOQ57_RS21130	COG0250	Participates in transcription elongation, termination and antitermination
BOQ57_RS21145	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BOQ57_RS21170	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BOQ57_RS21175	COG0569	domain protein
BOQ57_RS21180	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BOQ57_RS21200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BOQ57_RS21205	COG3005	denitrification pathway
BOQ57_RS21210	COG0243	molybdopterin cofactor binding
BOQ57_RS21240	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BOQ57_RS21260	COG2204	response regulator
BOQ57_RS21270	COG2205	protein histidine kinase activity
BOQ57_RS21290	COG5413	integral membrane protein
BOQ57_RS21300	COG1522	sequence-specific DNA binding
BOQ57_RS21305	COG2502	aspartate--ammonia ligase
BOQ57_RS21310	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BOQ57_RS21315	COG0542	response to heat
BOQ57_RS21325	COG0564	pseudouridine synthase activity
BOQ57_RS21330	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BOQ57_RS21335	COG0446	pyridine nucleotide-disulphide oxidoreductase
BOQ57_RS21345	COG3681	Belongs to the UPF0597 family
BOQ57_RS21355	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BOQ57_RS21360	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BOQ57_RS21365	COG1979	alcohol dehydrogenase
BOQ57_RS21370	COG2207	Transcriptional regulator
BOQ57_RS21375	COG3040	lipid binding
BOQ57_RS21385	COG0688	phosphatidylethanolamine metabolic process
BOQ57_RS21400	COG0540	Belongs to the ATCase OTCase family
BOQ57_RS21405	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BOQ57_RS21410	COG1438	arginine binding
BOQ57_RS21415	COG1288	antiporter activity
BOQ57_RS21420	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BOQ57_RS21445	COG0840	transmembrane signaling receptor activity
BOQ57_RS21465	COG3250	beta-galactosidase activity
BOQ57_RS21470	COG1609	Transcriptional regulator
BOQ57_RS21475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BOQ57_RS21485	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BOQ57_RS21490	COG2017	converts alpha-aldose to the beta-anomer
BOQ57_RS21495	COG0667	Aldo Keto reductase
BOQ57_RS21500	COG1968	undecaprenyl-diphosphatase activity
BOQ57_RS21505	COG3806	Anti-sigma factor
BOQ57_RS21510	COG1595	DNA-templated transcription, initiation
BOQ57_RS21530	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BOQ57_RS21535	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BOQ57_RS21540	COG0477	Major facilitator Superfamily
BOQ57_RS21555	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS21560	COG1131	(ABC) transporter
BOQ57_RS21565	COG0842	Transport permease protein
BOQ57_RS21570	COG0842	Transport permease protein
BOQ57_RS21575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BOQ57_RS21585	COG2116	formate transmembrane transporter activity
BOQ57_RS21590	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BOQ57_RS21590	COG1648	precorrin-2 dehydrogenase activity
BOQ57_RS21595	COG2239	Acts as a magnesium transporter
BOQ57_RS21605	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BOQ57_RS21610	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BOQ57_RS21620	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BOQ57_RS21630	COG0514	ATP-dependent DNA helicase (RecQ)
BOQ57_RS21635	COG2050	protein possibly involved in aromatic compounds catabolism
BOQ57_RS21655	COG2258	MOSC domain
BOQ57_RS21660	COG1177	transmembrane transport
BOQ57_RS21665	COG1176	ABC-type spermidine putrescine transport system, permease component I
BOQ57_RS21670	COG3842	ATPase activity
BOQ57_RS21690	COG0174	glutamine synthetase
BOQ57_RS21710	COG3045	CreA protein
BOQ57_RS21715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BOQ57_RS21720	COG0443	Heat shock 70 kDa protein
BOQ57_RS21735	COG0366	Alpha amylase catalytic
BOQ57_RS21750	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BOQ57_RS21755	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS21760	COG2205	protein histidine kinase activity
BOQ57_RS21770	COG0281	malic enzyme
BOQ57_RS21775	COG0702	epimerase
BOQ57_RS21780	COG0254	rRNA binding
BOQ57_RS21785	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BOQ57_RS21805	COG0129	dihydroxy-acid dehydratase activity
BOQ57_RS21815	COG3978	acetolactate synthase activity
BOQ57_RS21825	COG0606	chelatase, subunit chli
BOQ57_RS21830	COG0204	Acyl-transferase
BOQ57_RS21835	COG0204	Acyl-transferase
BOQ57_RS21840	COG1683	Conserved Protein
BOQ57_RS21850	COG1335	isochorismatase
BOQ57_RS21860	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BOQ57_RS21865	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BOQ57_RS21875	COG3084	Protein conserved in bacteria
BOQ57_RS21880	COG5001	Diguanylate cyclase
BOQ57_RS21880	COG4251	negative regulation of phosphorylation
BOQ57_RS21880	COG3706	GGDEF domain
BOQ57_RS21880	COG2203	Gaf domain
BOQ57_RS21885	COG0789	Transcriptional regulator
BOQ57_RS21895	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BOQ57_RS21900	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BOQ57_RS21905	COG1561	YicC-like family, N-terminal region
BOQ57_RS21925	COG3306	glycosyltransferase involved in LPS biosynthesis
BOQ57_RS21940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BOQ57_RS21950	COG0156	8-amino-7-oxononanoate synthase activity
BOQ57_RS21955	COG1063	alcohol dehydrogenase
BOQ57_RS21960	COG3245	cytochrome
BOQ57_RS21970	COG0210	DNA helicase
BOQ57_RS21975	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BOQ57_RS21980	COG2166	iron-sulfur cluster assembly
BOQ57_RS21985	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BOQ57_RS22020	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BOQ57_RS22025	COG4206	TonB-dependent receptor
BOQ57_RS22030	COG0583	DNA-binding transcription factor activity
BOQ57_RS22045	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BOQ57_RS22050	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BOQ57_RS22055	COG2223	nitrite transmembrane transporter activity
BOQ57_RS22060	COG3279	Response regulator of the LytR AlgR family
BOQ57_RS22065	COG3275	phosphorelay sensor kinase activity
BOQ57_RS22075	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS22075	COG2205	protein histidine kinase activity
BOQ57_RS22095	COG3188	usher protein
BOQ57_RS22115	COG2223	nitrite transmembrane transporter activity
BOQ57_RS22120	COG2081	HI0933 family
BOQ57_RS22125	COG1528	Iron-storage protein
BOQ57_RS22135	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BOQ57_RS22140	COG0589	response to stress
BOQ57_RS22180	COG3642	lipopolysaccharide core region biosynthetic process
BOQ57_RS22185	COG0859	PFAM glycosyl transferase family 9
BOQ57_RS22195	COG1758	RNA polymerase activity
BOQ57_RS22200	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BOQ57_RS22205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BOQ57_RS22210	COG2267	carboxylic ester hydrolase activity
BOQ57_RS22215	COG0561	phosphatase activity
BOQ57_RS22240	COG2271	Major facilitator Superfamily
BOQ57_RS22275	COG1309	transcriptional regulator
BOQ57_RS22280	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BOQ57_RS22285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BOQ57_RS22290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BOQ57_RS22290	COG4191	Histidine kinase
BOQ57_RS22295	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BOQ57_RS22320	COG2205	protein histidine kinase activity
BOQ57_RS22325	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS22330	COG2814	Major facilitator Superfamily
BOQ57_RS22345	COG3977	Valine--pyruvate aminotransferase
BOQ57_RS22350	COG0071	Belongs to the small heat shock protein (HSP20) family
BOQ57_RS22355	COG0071	Belongs to the small heat shock protein (HSP20) family
BOQ57_RS22360	COG2378	regulation of single-species biofilm formation
BOQ57_RS22375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BOQ57_RS22380	COG0592	DNA-directed DNA polymerase activity
BOQ57_RS22385	COG3074	FtsZ-dependent cytokinesis
BOQ57_RS22400	COG0745	RESPONSE REGULATOR receiver
BOQ57_RS22420	COG3036	rescue of stalled ribosome
BOQ57_RS22490	COG2716	regulation of RNA biosynthetic process
BOQ57_RS22505	COG1722	exodeoxyribonuclease VII activity
BOQ57_RS22540	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BOQ57_RS22625	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BOQ57_RS22650	COG1846	Transcriptional regulator