locus-tag	class	description
BFW97_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BFW97_RS00010	COG0592	DNA-directed DNA polymerase activity
BFW97_RS00030	COG2378	regulation of single-species biofilm formation
BFW97_RS00035	COG0071	Belongs to the small heat shock protein (HSP20) family
BFW97_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
BFW97_RS00045	COG3977	Valine--pyruvate aminotransferase
BFW97_RS00060	COG2814	Major facilitator Superfamily
BFW97_RS00065	COG0745	RESPONSE REGULATOR receiver
BFW97_RS00070	COG2205	protein histidine kinase activity
BFW97_RS00105	COG3550	peptidyl-serine autophosphorylation
BFW97_RS00140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW97_RS00145	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS00145	COG4191	Histidine kinase
BFW97_RS00150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_RS00155	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_RS00160	COG1309	transcriptional regulator
BFW97_RS00190	COG0469	pyruvate kinase activity
BFW97_RS00195	COG2271	Major facilitator Superfamily
BFW97_RS00220	COG0561	phosphatase activity
BFW97_RS00225	COG2267	carboxylic ester hydrolase activity
BFW97_RS00235	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFW97_RS00240	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW97_RS00245	COG1758	RNA polymerase activity
BFW97_RS00255	COG0859	PFAM glycosyl transferase family 9
BFW97_RS00260	COG3642	lipopolysaccharide core region biosynthetic process
BFW97_RS00300	COG0589	response to stress
BFW97_RS00305	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFW97_RS00315	COG1528	Iron-storage protein
BFW97_RS00320	COG2081	HI0933 family
BFW97_RS00325	COG2223	nitrite transmembrane transporter activity
BFW97_RS00345	COG3188	usher protein
BFW97_RS00365	COG2205	protein histidine kinase activity
BFW97_RS00365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS00375	COG3275	phosphorelay sensor kinase activity
BFW97_RS00380	COG3279	Response regulator of the LytR AlgR family
BFW97_RS00385	COG2223	nitrite transmembrane transporter activity
BFW97_RS00390	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BFW97_RS00395	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BFW97_RS00410	COG0583	DNA-binding transcription factor activity
BFW97_RS00415	COG4206	TonB-dependent receptor
BFW97_RS00420	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BFW97_RS00455	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BFW97_RS00460	COG2166	iron-sulfur cluster assembly
BFW97_RS00465	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFW97_RS00470	COG0210	DNA helicase
BFW97_RS00480	COG3245	cytochrome
BFW97_RS00485	COG1063	alcohol dehydrogenase
BFW97_RS00490	COG0156	8-amino-7-oxononanoate synthase activity
BFW97_RS00500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW97_RS00515	COG3306	glycosyltransferase involved in LPS biosynthesis
BFW97_RS00535	COG1561	YicC-like family, N-terminal region
BFW97_RS00540	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BFW97_RS00545	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BFW97_RS00555	COG0789	Transcriptional regulator
BFW97_RS00560	COG3706	GGDEF domain
BFW97_RS00560	COG4251	negative regulation of phosphorylation
BFW97_RS00560	COG5001	Diguanylate cyclase
BFW97_RS00560	COG2203	Gaf domain
BFW97_RS00565	COG3084	Protein conserved in bacteria
BFW97_RS00575	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BFW97_RS00580	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW97_RS00585	COG3639	organic phosphonate transmembrane transporter activity
BFW97_RS00590	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BFW97_RS00595	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BFW97_RS00605	COG1335	isochorismatase
BFW97_RS00615	COG1683	Conserved Protein
BFW97_RS00620	COG0204	Acyl-transferase
BFW97_RS00625	COG0204	Acyl-transferase
BFW97_RS00630	COG0606	chelatase, subunit chli
BFW97_RS00645	COG3978	acetolactate synthase activity
BFW97_RS00655	COG0129	dihydroxy-acid dehydratase activity
BFW97_RS00675	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BFW97_RS00680	COG0254	rRNA binding
BFW97_RS00685	COG0702	epimerase
BFW97_RS00690	COG0281	malic enzyme
BFW97_RS00700	COG2205	protein histidine kinase activity
BFW97_RS00705	COG0745	RESPONSE REGULATOR receiver
BFW97_RS00710	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW97_RS00725	COG0366	Alpha amylase catalytic
BFW97_RS00740	COG0443	Heat shock 70 kDa protein
BFW97_RS00745	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFW97_RS00750	COG3045	CreA protein
BFW97_RS00770	COG0174	glutamine synthetase
BFW97_RS00790	COG3842	ATPase activity
BFW97_RS00795	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW97_RS00800	COG1177	transmembrane transport
BFW97_RS00805	COG2258	MOSC domain
BFW97_RS00820	COG2050	protein possibly involved in aromatic compounds catabolism
BFW97_RS00825	COG0514	ATP-dependent DNA helicase (RecQ)
BFW97_RS00835	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BFW97_RS00845	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BFW97_RS00850	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFW97_RS00860	COG2239	Acts as a magnesium transporter
BFW97_RS00865	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW97_RS00865	COG1648	precorrin-2 dehydrogenase activity
BFW97_RS00870	COG2116	formate transmembrane transporter activity
BFW97_RS00880	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_RS00895	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BFW97_RS00900	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BFW97_RS00920	COG1595	DNA-templated transcription, initiation
BFW97_RS00925	COG3806	Anti-sigma factor
BFW97_RS00930	COG1968	undecaprenyl-diphosphatase activity
BFW97_RS00935	COG0667	Aldo Keto reductase
BFW97_RS00940	COG2017	converts alpha-aldose to the beta-anomer
BFW97_RS00945	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BFW97_RS00955	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW97_RS00960	COG1609	Transcriptional regulator
BFW97_RS00965	COG3250	beta-galactosidase activity
BFW97_RS00985	COG0840	transmembrane signaling receptor activity
BFW97_RS01015	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFW97_RS01020	COG1288	antiporter activity
BFW97_RS01025	COG1438	arginine binding
BFW97_RS01030	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BFW97_RS01035	COG0540	Belongs to the ATCase OTCase family
BFW97_RS01050	COG0688	phosphatidylethanolamine metabolic process
BFW97_RS01060	COG3040	lipid binding
BFW97_RS01065	COG2207	Transcriptional regulator
BFW97_RS01070	COG1979	alcohol dehydrogenase
BFW97_RS01075	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BFW97_RS01080	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BFW97_RS01090	COG2964	Protein conserved in bacteria
BFW97_RS01095	COG3681	Belongs to the UPF0597 family
BFW97_RS01105	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_RS01110	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_RS01115	COG0564	pseudouridine synthase activity
BFW97_RS01125	COG0542	response to heat
BFW97_RS01130	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BFW97_RS01140	COG2502	aspartate--ammonia ligase
BFW97_RS01145	COG1522	sequence-specific DNA binding
BFW97_RS01155	COG5413	integral membrane protein
BFW97_RS01180	COG2205	protein histidine kinase activity
BFW97_RS01190	COG2204	response regulator
BFW97_RS01210	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BFW97_RS01240	COG0243	molybdopterin cofactor binding
BFW97_RS01245	COG3005	denitrification pathway
BFW97_RS01250	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BFW97_RS01270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW97_RS01275	COG0569	domain protein
BFW97_RS01280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BFW97_RS01305	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW97_RS01320	COG0250	Participates in transcription elongation, termination and antitermination
BFW97_RS01325	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BFW97_RS01330	COG0081	regulation of translation
BFW97_RS01335	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BFW97_RS01340	COG0222	ribosome binding
BFW97_RS01345	COG0085	RNA polymerase activity
BFW97_RS01350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BFW97_RS01360	COG2964	Protein conserved in bacteria
BFW97_RS01365	COG0251	oxidation-reduction process
BFW97_RS01375	COG2923	Belongs to the DsrF TusC family
BFW97_RS01380	COG2168	tRNA wobble position uridine thiolation
BFW97_RS01385	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BFW97_RS01390	COG0049	tRNA binding
BFW97_RS01395	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BFW97_RS01400	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BFW97_RS01405	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFW97_RS01445	COG2252	PERMEase
BFW97_RS01450	COG2376	Dihydroxyacetone kinase
BFW97_RS01455	COG1461	Dihydroxyacetone kinase
BFW97_RS01470	COG3284	Transcriptional regulator
BFW97_RS01480	COG2957	Belongs to the agmatine deiminase family
BFW97_RS01485	COG4221	oxidoreductase activity
BFW97_RS01490	COG0628	permease
BFW97_RS01495	COG0494	nUDIX hydrolase
BFW97_RS01520	COG0753	catalase activity
BFW97_RS01525	COG1247	-acetyltransferase
BFW97_RS01545	COG2203	Gaf domain
BFW97_RS01545	COG2199	diguanylate cyclase activity
BFW97_RS01555	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFW97_RS01565	COG1175	transmembrane transport
BFW97_RS01595	COG0583	DNA-binding transcription factor activity
BFW97_RS01605	COG1741	Belongs to the pirin family
BFW97_RS01610	COG2259	Doxx family
BFW97_RS01615	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BFW97_RS01620	COG1074	ATP-dependent DNA helicase activity
BFW97_RS01625	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BFW97_RS01630	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFW97_RS01635	COG0346	lactoylglutathione lyase activity
BFW97_RS01680	COG3706	GGDEF domain
BFW97_RS01680	COG2203	Gaf domain
BFW97_RS01680	COG5001	Diguanylate cyclase
BFW97_RS01680	COG4251	negative regulation of phosphorylation
BFW97_RS01685	COG4771	TonB-dependent receptor
BFW97_RS01690	COG1278	Cold shock
BFW97_RS01715	COG0629	single-stranded DNA binding
BFW97_RS01720	COG2197	response regulator
BFW97_RS01725	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BFW97_RS01735	COG3047	cAMP biosynthetic process
BFW97_RS01740	COG0840	transmembrane signaling receptor activity
BFW97_RS01765	COG3135	benzoate transporter
BFW97_RS01770	COG1396	sequence-specific DNA binding
BFW97_RS01805	COG2926	Belongs to the UPF0265 family
BFW97_RS01815	COG3028	Belongs to the UPF0307 family
BFW97_RS01820	COG0312	modulator of DNA gyrase
BFW97_RS01825	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BFW97_RS01830	COG5007	Belongs to the BolA IbaG family
BFW97_RS01840	COG2854	intermembrane phospholipid transfer
BFW97_RS01845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW97_RS01850	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BFW97_RS01855	COG1127	ABC transporter
BFW97_RS01860	COG0517	IMP dehydrogenase activity
BFW97_RS01860	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFW97_RS01865	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BFW97_RS01870	COG3117	lipopolysaccharide transmembrane transporter activity
BFW97_RS01875	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BFW97_RS01880	COG1137	ATPase activity
BFW97_RS01885	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BFW97_RS01895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS01900	COG1660	Displays ATPase and GTPase activities
BFW97_RS01905	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS01910	COG3711	transcriptional antiterminator
BFW97_RS01910	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS01925	COG3964	amidohydrolase
BFW97_RS01955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW97_RS01960	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BFW97_RS01970	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BFW97_RS01975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BFW97_RS01980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BFW97_RS01985	COG0723	plastoquinol--plastocyanin reductase activity
BFW97_RS01990	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BFW97_RS01995	COG2857	Cytochrome c1
BFW97_RS02000	COG0625	glutathione transferase activity
BFW97_RS02005	COG2969	positive regulation of protein catabolic process
BFW97_RS02010	COG2823	Periplasmic or secreted lipoprotein
BFW97_RS02015	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFW97_RS02020	COG0792	nuclease activity
BFW97_RS02025	COG3107	peptidoglycan biosynthetic process
BFW97_RS02030	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BFW97_RS02040	COG2001	Belongs to the MraZ family
BFW97_RS02045	COG0275	rRNA processing
BFW97_RS02050	COG3116	cell division
BFW97_RS02055	COG0768	penicillin binding
BFW97_RS02065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BFW97_RS02070	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFW97_RS02075	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BFW97_RS02080	COG0772	Belongs to the SEDS family
BFW97_RS02085	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BFW97_RS02090	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW97_RS02095	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BFW97_RS02100	COG0849	cell division
BFW97_RS02105	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BFW97_RS02110	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BFW97_RS02120	COG0653	protein targeting
BFW97_RS02130	COG0494	nUDIX hydrolase
BFW97_RS02135	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BFW97_RS02140	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BFW97_RS02155	COG1459	type II secretion system
BFW97_RS02160	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW97_RS02190	COG2186	Transcriptional regulator
BFW97_RS02195	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BFW97_RS02200	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW97_RS02205	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BFW97_RS02210	COG5002	protein histidine kinase activity
BFW97_RS02210	COG3447	MASE1 domain protein
BFW97_RS02210	COG5001	Diguanylate cyclase
BFW97_RS02220	COG0840	transmembrane signaling receptor activity
BFW97_RS02225	COG0840	transmembrane signaling receptor activity
BFW97_RS02230	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFW97_RS02235	COG1049	propionate catabolic process, 2-methylcitrate cycle
BFW97_RS02250	COG1280	lysine exporter protein (LysE YggA)
BFW97_RS02260	COG0523	cobalamin synthesis protein
BFW97_RS02265	COG0477	Major facilitator Superfamily
BFW97_RS02280	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BFW97_RS02285	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BFW97_RS02325	COG3314	Sporulation integral membrane protein YlbJ
BFW97_RS02330	COG0784	Response regulator, receiver
BFW97_RS02330	COG0835	chemotaxis
BFW97_RS02335	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_RS02340	COG1444	tRNA N-acetyltransferase activity
BFW97_RS02365	COG1803	Methylglyoxal synthase
BFW97_RS02380	COG0252	asparaginase activity
BFW97_RS02400	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS02400	COG1263	PTS System
BFW97_RS02405	COG0366	Alpha amylase catalytic
BFW97_RS02410	COG0110	maltose O-acetyltransferase activity
BFW97_RS02415	COG1522	sequence-specific DNA binding
BFW97_RS02420	COG5006	permease, DMT superfamily
BFW97_RS02430	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_RS02435	COG1177	transmembrane transport
BFW97_RS02440	COG1176	ABC-type spermidine putrescine transport system, permease component I
BFW97_RS02445	COG3842	ATPase activity
BFW97_RS02450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BFW97_RS02455	COG0583	DNA-binding transcription factor activity
BFW97_RS02460	COG1757	Na H antiporter
BFW97_RS02500	COG0297	glycogen (starch) synthase activity
BFW97_RS02505	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW97_RS02510	COG2813	Specifically methylates the guanine in position
BFW97_RS02515	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW97_RS02520	COG5001	Diguanylate cyclase
BFW97_RS02520	COG2203	Gaf domain
BFW97_RS02520	COG3706	GGDEF domain
BFW97_RS02520	COG4251	negative regulation of phosphorylation
BFW97_RS02530	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_RS02540	COG2995	paraquat-inducible protein a
BFW97_RS02545	COG3008	intermembrane lipid transfer
BFW97_RS02545	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BFW97_RS02550	COG3009	Protein conserved in bacteria
BFW97_RS02565	COG3240	lipase activity
BFW97_RS02570	COG3111	PFAM Bacterial OB fold (BOF) protein
BFW97_RS02580	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BFW97_RS02585	COG1194	a g-specific adenine glycosylase
BFW97_RS02595	COG3409	Peptidoglycan-binding domain 1 protein
BFW97_RS02595	COG3267	Type II secretory pathway component ExeA
BFW97_RS02605	COG0617	tRNA 3'-terminal CCA addition
BFW97_RS02620	COG1346	cytolysis
BFW97_RS02625	COG1380	Effector of murein hydrolase LrgA
BFW97_RS02630	COG0583	DNA-binding transcription factor activity
BFW97_RS02655	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BFW97_RS02660	COG0306	phosphate transporter
BFW97_RS02665	COG1392	Phosphate transport regulator
BFW97_RS02680	COG1560	Kdo2-lipid A biosynthetic process
BFW97_RS02685	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BFW97_RS02685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BFW97_RS02690	COG1538	Outer membrane efflux protein
BFW97_RS02695	COG0494	nUDIX hydrolase
BFW97_RS02700	COG3151	Protein conserved in bacteria
BFW97_RS02710	COG3150	esterase
BFW97_RS02715	COG1051	belongs to the nudix hydrolase family
BFW97_RS02730	COG1566	PFAM secretion protein HlyD family protein
BFW97_RS02735	COG1289	transmembrane transporter activity
BFW97_RS02785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW97_RS02810	COG0204	Acyl-transferase
BFW97_RS02815	COG1842	Phage shock protein A
BFW97_RS02830	COG2827	Endonuclease containing a URI domain
BFW97_RS02840	COG2962	Rard protein
BFW97_RS02845	COG1573	uracil-dna glycosylase
BFW97_RS02850	COG0697	spore germination
BFW97_RS02860	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BFW97_RS02865	COG1121	(ABC) transporter
BFW97_RS02870	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BFW97_RS02890	COG0739	heme binding
BFW97_RS02900	COG3068	Protein conserved in bacteria
BFW97_RS02920	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BFW97_RS02925	COG0582	viral genome integration into host DNA
BFW97_RS02950	COG1546	Belongs to the CinA family
BFW97_RS02955	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BFW97_RS02965	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BFW97_RS02970	COG0527	aspartate kinase activity
BFW97_RS02975	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BFW97_RS03010	COG1686	Belongs to the peptidase S11 family
BFW97_RS03015	COG0586	Pfam SNARE associated Golgi protein
BFW97_RS03020	COG1253	flavin adenine dinucleotide binding
BFW97_RS03025	COG0525	valine-tRNA ligase activity
BFW97_RS03030	COG2927	DNA polymerase III (CHI subunit)
BFW97_RS03035	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW97_RS03040	COG0795	lipopolysaccharide-transporting ATPase activity
BFW97_RS03045	COG0795	lipopolysaccharide-transporting ATPase activity
BFW97_RS03170	COG4695	Portal protein
BFW97_RS03265	COG2932	Transcriptional regulator
BFW97_RS03275	COG4974	Belongs to the 'phage' integrase family
BFW97_RS03280	COG0582	viral genome integration into host DNA
BFW97_RS03295	COG3561	AntA/AntB antirepressor
BFW97_RS03320	COG0004	ammonium transporteR
BFW97_RS03325	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW97_RS03335	COG2165	general secretion pathway protein
BFW97_RS03340	COG0084	hydrolase, TatD family'
BFW97_RS03345	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_RS03355	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFW97_RS03360	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BFW97_RS03365	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BFW97_RS03370	COG0813	purine-nucleoside phosphorylase activity
BFW97_RS03375	COG5001	Diguanylate cyclase
BFW97_RS03375	COG3447	MASE1 domain protein
BFW97_RS03375	COG5002	protein histidine kinase activity
BFW97_RS03385	COG0560	Phosphoserine phosphatase
BFW97_RS03410	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BFW97_RS03415	COG0776	regulation of translation
BFW97_RS03430	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFW97_RS03435	COG0735	belongs to the Fur family
BFW97_RS03460	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BFW97_RS03465	COG0513	Belongs to the DEAD box helicase family
BFW97_RS03470	COG3022	response to hydroperoxide
BFW97_RS03485	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BFW97_RS03490	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BFW97_RS03495	COG0762	integral membrane protein
BFW97_RS03500	COG1872	DUF167
BFW97_RS03515	COG4166	transmembrane transport
BFW97_RS03525	COG0110	maltose O-acetyltransferase activity
BFW97_RS03535	COG1024	Enoyl-CoA hydratase
BFW97_RS03550	COG4221	oxidoreductase activity
BFW97_RS03555	COG0442	prolyl-tRNA aminoacylation
BFW97_RS03560	COG0840	transmembrane signaling receptor activity
BFW97_RS03565	COG0632	four-way junction helicase activity
BFW97_RS03570	COG2255	four-way junction helicase activity
BFW97_RS03575	COG1271	oxidase subunit
BFW97_RS03580	COG1294	oxidase, subunit
BFW97_RS03585	COG4890	Cyd operon protein YbgT
BFW97_RS03590	COG3790	cyd operon protein YbgE
BFW97_RS03595	COG0824	Thioesterase
BFW97_RS03600	COG0811	peptide transport
BFW97_RS03615	COG0823	Involved in the tonB-independent uptake of proteins
BFW97_RS03620	COG2885	chlorophyll binding
BFW97_RS03625	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BFW97_RS03700	COG0840	transmembrane signaling receptor activity
BFW97_RS03705	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BFW97_RS03710	COG0676	glucose-6-phosphate 1-epimerase activity
BFW97_RS03715	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFW97_RS03720	COG1640	4-alpha-glucanotransferase
BFW97_RS03725	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BFW97_RS03745	COG1051	belongs to the nudix hydrolase family
BFW97_RS03750	COG2130	NADP-dependent
BFW97_RS03755	COG1764	response to oxidative stress
BFW97_RS03760	COG1846	Transcriptional regulator
BFW97_RS03790	COG0561	phosphatase activity
BFW97_RS03805	COG0733	neurotransmitter:sodium symporter activity
BFW97_RS03815	COG0733	neurotransmitter:sodium symporter activity
BFW97_RS03840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW97_RS03855	COG1794	racemase activity, acting on amino acids and derivatives
BFW97_RS03870	COG2731	YhcH YjgK YiaL family protein
BFW97_RS03880	COG0668	transmembrane transport
BFW97_RS03890	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW97_RS03935	COG0583	DNA-binding transcription factor activity
BFW97_RS03940	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BFW97_RS03950	COG0488	(ABC) transporter
BFW97_RS03955	COG0517	IMP dehydrogenase activity
BFW97_RS03955	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BFW97_RS03960	COG1585	Membrane protein implicated in regulation of membrane protease activity
BFW97_RS03965	COG0330	HflC and HflK could
BFW97_RS03970	COG1648	precorrin-2 dehydrogenase activity
BFW97_RS03970	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW97_RS03975	COG0175	sulfate reduction
BFW97_RS03980	COG2895	sulfate adenylyltransferase (ATP) activity
BFW97_RS03985	COG0471	metal ion transport
BFW97_RS03985	COG3273	potassium ion transport
BFW97_RS03990	COG0529	Catalyzes the synthesis of activated sulfate
BFW97_RS04020	COG0840	transmembrane signaling receptor activity
BFW97_RS04040	COG1136	(ABC) transporter
BFW97_RS04055	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BFW97_RS04075	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BFW97_RS04080	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BFW97_RS04085	COG0163	prenyltransferase activity
BFW97_RS04100	COG1131	(ABC) transporter
BFW97_RS04105	COG0842	Transport permease protein
BFW97_RS04110	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BFW97_RS04115	COG1924	4 iron, 4 sulfur cluster binding
BFW97_RS04135	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BFW97_RS04140	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BFW97_RS04155	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_RS04160	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BFW97_RS04165	COG1489	DNA binding
BFW97_RS04175	COG1643	Atp-dependent helicase
BFW97_RS04180	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFW97_RS04185	COG0346	lactoylglutathione lyase activity
BFW97_RS04195	COG2076	Multidrug Resistance protein
BFW97_RS04205	COG0784	Response regulator, receiver
BFW97_RS04205	COG3437	response regulator, receiver
BFW97_RS04215	COG0671	phosphoesterase, PA-phosphatase related
BFW97_RS04230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFW97_RS04235	COG0038	chloride channel
BFW97_RS04245	COG0316	Belongs to the HesB IscA family
BFW97_RS04270	COG1280	lysine exporter protein (LysE YggA)
BFW97_RS04275	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BFW97_RS04290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_RS04320	COG0745	RESPONSE REGULATOR receiver
BFW97_RS04325	COG3104	oligopeptide transport
BFW97_RS04330	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BFW97_RS04335	COG1555	photosystem II stabilization
BFW97_RS04345	COG2350	Protein conserved in bacteria
BFW97_RS04350	COG2917	probably involved in intracellular septation
BFW97_RS04355	COG0076	glutamate decarboxylase activity
BFW97_RS04360	COG1272	protein, Hemolysin III
BFW97_RS04365	COG0569	domain protein
BFW97_RS04365	COG2985	domain, Protein
BFW97_RS04415	COG0835	chemotaxis
BFW97_RS04415	COG0784	Response regulator, receiver
BFW97_RS04420	COG2755	lipolytic protein G-D-S-L family
BFW97_RS04425	COG4181	ATPase activity
BFW97_RS04430	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BFW97_RS04435	COG1090	epimerase
BFW97_RS04440	COG2200	EAL domain
BFW97_RS04445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW97_RS04450	COG2234	aminopeptidase activity
BFW97_RS04450	COG4935	Belongs to the peptidase S8 family
BFW97_RS04455	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BFW97_RS04460	COG3171	Protein conserved in bacteria
BFW97_RS04465	COG2066	Belongs to the glutaminase family
BFW97_RS04470	COG2897	thiosulfate sulfurtransferase activity
BFW97_RS04475	COG1404	Belongs to the peptidase S8 family
BFW97_RS04485	COG1132	(ABC) transporter
BFW97_RS04520	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BFW97_RS04525	COG3300	MHYT domain
BFW97_RS04525	COG5001	Diguanylate cyclase
BFW97_RS04545	COG4628	conserved protein (DUF2132)
BFW97_RS04550	COG0688	phosphatidylethanolamine metabolic process
BFW97_RS04555	COG1162	GTPase activity
BFW97_RS04560	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BFW97_RS04600	COG1278	Cold shock
BFW97_RS04610	COG0840	transmembrane signaling receptor activity
BFW97_RS04615	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_RS04620	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_RS04625	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_RS04670	COG0848	biopolymer transport protein
BFW97_RS04675	COG0811	peptide transport
BFW97_RS04680	COG0811	peptide transport
BFW97_RS04695	COG4174	ABC transporter (Permease)
BFW97_RS04700	COG4239	(ABC) transporter, permease
BFW97_RS04710	COG0444	Belongs to the ABC transporter superfamily
BFW97_RS04715	COG4608	Belongs to the ABC transporter superfamily
BFW97_RS04725	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFW97_RS04735	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BFW97_RS04740	COG1073	alpha beta
BFW97_RS04755	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BFW97_RS04780	COG0243	molybdopterin cofactor binding
BFW97_RS04795	COG1116	anion transmembrane transporter activity
BFW97_RS04795	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BFW97_RS04800	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BFW97_RS04805	COG1116	anion transmembrane transporter activity
BFW97_RS04810	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_RS04810	COG2146	nitrite reductase [NAD(P)H] activity
BFW97_RS04815	COG2146	nitrite reductase [NAD(P)H] activity
BFW97_RS04815	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_RS04820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_RS04825	COG2313	pseudouridylate synthase activity
BFW97_RS04835	COG1858	cytochrome C peroxidase
BFW97_RS04870	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW97_RS04875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW97_RS04900	COG2986	histidine ammonia-lyase
BFW97_RS04925	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW97_RS04935	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_RS04950	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW97_RS04960	COG2966	Psort location CytoplasmicMembrane, score
BFW97_RS04965	COG3610	response to peptide
BFW97_RS04975	COG4175	Glycine betaine
BFW97_RS04980	COG4176	ABC-type proline glycine betaine transport system permease component
BFW97_RS04985	COG2113	Glycine betaine
BFW97_RS04990	COG0175	sulfate reduction
BFW97_RS04995	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BFW97_RS05000	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BFW97_RS05005	COG0384	phenazine biosynthesis protein PhzF
BFW97_RS05010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BFW97_RS05025	COG0786	glutamate:sodium symporter activity
BFW97_RS05030	COG0252	asparaginase activity
BFW97_RS05035	COG3139	Protein of unknown function (DUF1315)
BFW97_RS05055	COG0616	signal peptide processing
BFW97_RS05060	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_RS05060	COG1902	pentaerythritol trinitrate reductase activity
BFW97_RS05065	COG0778	Nitroreductase
BFW97_RS05080	COG2264	protein methyltransferase activity
BFW97_RS05085	COG0604	alcohol dehydrogenase
BFW97_RS05090	COG0583	DNA-binding transcription factor activity
BFW97_RS05095	COG2190	(PTS) system
BFW97_RS05095	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS05095	COG1263	PTS System
BFW97_RS05100	COG4145	pantothenate transmembrane transporter activity
BFW97_RS05110	COG0439	Biotin carboxylase
BFW97_RS05115	COG0511	ligase activity, forming carbon-carbon bonds
BFW97_RS05120	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BFW97_RS05125	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW97_RS05135	COG5001	Diguanylate cyclase
BFW97_RS05135	COG3300	MHYT domain
BFW97_RS05155	COG3381	protein complex oligomerization
BFW97_RS05165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BFW97_RS05180	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BFW97_RS05185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW97_RS05185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BFW97_RS05205	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BFW97_RS05210	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW97_RS05215	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BFW97_RS05220	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BFW97_RS05225	COG4172	Belongs to the ABC transporter superfamily
BFW97_RS05235	COG0601	transmembrane transport
BFW97_RS05245	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BFW97_RS05250	COG0142	geranyltranstransferase activity
BFW97_RS05255	COG1722	exodeoxyribonuclease VII activity
BFW97_RS05260	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW97_RS05265	COG1360	Flagellar Motor Protein
BFW97_RS05280	COG1534	Rna-binding protein
BFW97_RS05285	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BFW97_RS05295	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BFW97_RS05300	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BFW97_RS05305	COG0149	triose-phosphate isomerase activity
BFW97_RS05310	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BFW97_RS05325	COG0779	Required for maturation of 30S ribosomal subunits
BFW97_RS05330	COG0195	Participates in both transcription termination and antitermination
BFW97_RS05335	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BFW97_RS05340	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BFW97_RS05345	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BFW97_RS05350	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BFW97_RS05355	COG1185	polyribonucleotide nucleotidyltransferase activity
BFW97_RS05370	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BFW97_RS05380	COG0114	fumarate hydratase activity
BFW97_RS05390	COG1966	Carbon starvation protein
BFW97_RS05395	COG3279	Response regulator of the LytR AlgR family
BFW97_RS05465	COG0312	modulator of DNA gyrase
BFW97_RS05470	COG0312	modulator of DNA gyrase
BFW97_RS05480	COG4974	Belongs to the 'phage' integrase family
BFW97_RS05485	COG1970	mechanosensitive ion channel activity
BFW97_RS05490	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW97_RS05500	COG0789	Transcriptional regulator
BFW97_RS05515	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_RS05520	COG3545	Serine hydrolase
BFW97_RS05530	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BFW97_RS05540	COG0321	lipoyl(octanoyl) transferase activity
BFW97_RS05545	COG2921	Belongs to the UPF0250 family
BFW97_RS05550	COG1686	Belongs to the peptidase S11 family
BFW97_RS05555	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BFW97_RS05560	COG2951	lytic endotransglycosylase activity
BFW97_RS05565	COG0772	Belongs to the SEDS family
BFW97_RS05570	COG0772	Belongs to the SEDS family
BFW97_RS05575	COG0768	penicillin binding
BFW97_RS05580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BFW97_RS05585	COG0799	negative regulation of ribosome biogenesis
BFW97_RS05590	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BFW97_RS05605	COG0495	leucyl-tRNA aminoacylation
BFW97_RS05610	COG2888	peptidyl-tyrosine sulfation
BFW97_RS05615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BFW97_RS05620	COG4535	Mg2 and Co2 transporter CorC
BFW97_RS05625	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BFW97_RS05630	COG1702	phosphate starvation-inducible protein PhoH
BFW97_RS05635	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW97_RS05640	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW97_RS05645	COG1335	isochorismatase
BFW97_RS05655	COG3706	GGDEF domain
BFW97_RS05670	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_RS05690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BFW97_RS05700	COG3647	Membrane
BFW97_RS05705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BFW97_RS05715	COG0516	GMP reductase activity
BFW97_RS05725	COG0642	Histidine kinase
BFW97_RS05765	COG3214	Protein conserved in bacteria
BFW97_RS05790	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BFW97_RS05795	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BFW97_RS05800	COG1053	succinate dehydrogenase
BFW97_RS05810	COG0584	glycerophosphoryl diester phosphodiesterase
BFW97_RS05815	COG3264	Mechanosensitive ion channel
BFW97_RS05815	COG1511	domain protein
BFW97_RS05825	COG0739	heme binding
BFW97_RS05840	COG0583	DNA-binding transcription factor activity
BFW97_RS05860	COG0583	DNA-binding transcription factor activity
BFW97_RS05865	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BFW97_RS05895	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BFW97_RS05900	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BFW97_RS05910	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BFW97_RS05915	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BFW97_RS05925	COG0180	Tryptophanyl-tRNA synthetase
BFW97_RS05940	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BFW97_RS05950	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_RS05960	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_RS05970	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_RS05970	COG0674	pyruvate-flavodoxin oxidoreductase activity
BFW97_RS05970	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BFW97_RS05970	COG1013	pyruvate-flavodoxin oxidoreductase activity
BFW97_RS05980	COG0366	Alpha amylase catalytic
BFW97_RS06000	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BFW97_RS06010	COG0490	domain, Protein
BFW97_RS06010	COG0471	metal ion transport
BFW97_RS06055	COG0012	GTP binding
BFW97_RS06065	COG0737	Belongs to the 5'-nucleotidase family
BFW97_RS06070	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BFW97_RS06080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BFW97_RS06085	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BFW97_RS06090	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BFW97_RS06095	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BFW97_RS06100	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW97_RS06110	COG2912	Transglutaminase-like superfamily
BFW97_RS06115	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BFW97_RS06120	COG1301	dicarboxylic acid transport
BFW97_RS06130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BFW97_RS06145	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFW97_RS06150	COG1115	amino acid carrier protein
BFW97_RS06165	COG0714	Associated with various cellular activities
BFW97_RS06175	COG3104	oligopeptide transport
BFW97_RS06180	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BFW97_RS06185	COG1678	Uncharacterized ACR, COG1678
BFW97_RS06195	COG0189	ligase activity
BFW97_RS06200	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BFW97_RS06210	COG3091	SprT-like family
BFW97_RS06220	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BFW97_RS06225	COG3710	Transcriptional regulator
BFW97_RS06245	COG2200	EAL domain
BFW97_RS06275	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BFW97_RS06280	COG0739	heme binding
BFW97_RS06285	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFW97_RS06290	COG3408	Glycogen debranching enzyme
BFW97_RS06290	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BFW97_RS06300	COG1881	PFAM PEBP family protein
BFW97_RS06305	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BFW97_RS06310	COG0583	DNA-binding transcription factor activity
BFW97_RS06320	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFW97_RS06330	COG0583	DNA-binding transcription factor activity
BFW97_RS06335	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_RS06340	COG0616	signal peptide processing
BFW97_RS06345	COG3724	N-succinylarginine dihydrolase activity
BFW97_RS06365	COG0840	transmembrane signaling receptor activity
BFW97_RS06375	COG2971	BadF BadG BcrA BcrD
BFW97_RS06385	COG4608	Belongs to the ABC transporter superfamily
BFW97_RS06390	COG0444	Belongs to the ABC transporter superfamily
BFW97_RS06395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_RS06400	COG0601	transmembrane transport
BFW97_RS06405	COG4166	transmembrane transport
BFW97_RS06410	COG0784	Response regulator, receiver
BFW97_RS06410	COG2205	protein histidine kinase activity
BFW97_RS06440	COG3220	belongs to the UPF0276 family
BFW97_RS06470	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_RS06475	COG1289	transmembrane transporter activity
BFW97_RS06480	COG0303	'Molybdopterin
BFW97_RS06485	COG0746	molybdenum cofactor guanylyltransferase activity
BFW97_RS06495	COG4662	Binding-protein-dependent transport system inner membrane component
BFW97_RS06505	COG2204	response regulator
BFW97_RS06510	COG3852	Histidine kinase
BFW97_RS06515	COG1910	domain protein
BFW97_RS06520	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFW97_RS06560	COG3383	formate dehydrogenase (NAD+) activity
BFW97_RS06560	COG3383	formate dehydrogenase (NAD+) activity
BFW97_RS06565	COG0437	4 iron, 4 sulfur cluster binding
BFW97_RS06580	COG0281	malic enzyme
BFW97_RS06600	COG2706	6-phosphogluconolactonase activity
BFW97_RS06610	COG1196	nuclear chromosome segregation
BFW97_RS06610	COG3264	Mechanosensitive ion channel
BFW97_RS06615	COG0469	pyruvate kinase activity
BFW97_RS06630	COG4651	solute:proton antiporter activity
BFW97_RS06630	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFW97_RS06640	COG2974	May be involved in recombination
BFW97_RS06650	COG0420	3'-5' exonuclease activity
BFW97_RS06655	COG0419	ATPase involved in DNA repair
BFW97_RS06670	COG3038	cytochrome b561
BFW97_RS06685	COG2190	(PTS) system
BFW97_RS06695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS06700	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BFW97_RS06705	COG0542	response to heat
BFW97_RS06720	COG1720	tRNA m6t6A37 methyltransferase activity
BFW97_RS06740	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BFW97_RS06745	COG4988	ABC transporter
BFW97_RS06760	COG0745	RESPONSE REGULATOR receiver
BFW97_RS06770	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BFW97_RS06785	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BFW97_RS06790	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BFW97_RS06805	COG0083	homoserine kinase activity
BFW97_RS06810	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BFW97_RS06815	COG4319	ketosteroid isomerase
BFW97_RS06830	COG0488	(ABC) transporter
BFW97_RS06835	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BFW97_RS06845	COG0813	purine-nucleoside phosphorylase activity
BFW97_RS06860	COG2205	protein histidine kinase activity
BFW97_RS06860	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS06865	COG3384	dioxygenase
BFW97_RS06875	COG1283	sodium-dependent phosphate transmembrane transporter activity
BFW97_RS06885	COG0531	amino acid
BFW97_RS06895	COG0531	amino acid
BFW97_RS06910	COG1917	Cupin 2, conserved barrel domain protein
BFW97_RS06910	COG1396	sequence-specific DNA binding
BFW97_RS06915	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_RS06935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_RS06945	COG2375	cellular response to nickel ion
BFW97_RS06955	COG1136	(ABC) transporter
BFW97_RS06955	COG0577	efflux transmembrane transporter activity
BFW97_RS06960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_RS06970	COG1227	inorganic diphosphatase activity
BFW97_RS06980	COG0497	DNA recombination
BFW97_RS06985	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BFW97_RS06990	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BFW97_RS06995	COG0443	Heat shock 70 kDa protein
BFW97_RS07000	COG0484	heat shock protein binding
BFW97_RS07030	COG1285	pathogenesis
BFW97_RS07045	COG0640	Transcriptional regulator
BFW97_RS07075	COG0095	Lipoate-protein ligase
BFW97_RS07095	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_RS07100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_RS07120	COG0708	Exodeoxyribonuclease III
BFW97_RS07135	COG2211	Major facilitator Superfamily
BFW97_RS07180	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BFW97_RS07185	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BFW97_RS07190	COG1845	cytochrome c oxidase, subunit III
BFW97_RS07195	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BFW97_RS07200	COG0109	protoheme IX farnesyltransferase activity
BFW97_RS07205	COG2814	Major facilitator Superfamily
BFW97_RS07215	COG2198	Histidine kinase
BFW97_RS07215	COG2205	protein histidine kinase activity
BFW97_RS07215	COG0784	Response regulator, receiver
BFW97_RS07220	COG1879	ABC-type sugar transport system periplasmic component
BFW97_RS07230	COG0745	RESPONSE REGULATOR receiver
BFW97_RS07235	COG3005	denitrification pathway
BFW97_RS07245	COG3381	protein complex oligomerization
BFW97_RS07285	COG2003	Belongs to the UPF0758 family
BFW97_RS07325	COG0583	DNA-binding transcription factor activity
BFW97_RS07340	COG0549	Belongs to the carbamate kinase family
BFW97_RS07345	COG1304	FMN binding
BFW97_RS07350	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BFW97_RS07355	COG1335	isochorismatase
BFW97_RS07370	COG3311	Transcriptional regulator
BFW97_RS07395	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_RS07430	COG0159	tryptophan synthase activity
BFW97_RS07435	COG0133	tryptophan synthase activity
BFW97_RS07440	COG0135	phosphoribosylanthranilate isomerase activity
BFW97_RS07440	COG0134	indole-3-glycerol-phosphate synthase activity
BFW97_RS07445	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFW97_RS07450	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BFW97_RS07450	COG0512	Glutamine amidotransferase of anthranilate synthase
BFW97_RS07455	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BFW97_RS07465	COG0009	L-threonylcarbamoyladenylate synthase
BFW97_RS07475	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BFW97_RS07485	COG1946	Acyl-CoA thioesterase
BFW97_RS07500	COG1309	transcriptional regulator
BFW97_RS07505	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_RS07510	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_RS07520	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFW97_RS07540	COG2244	polysaccharide biosynthetic process
BFW97_RS07550	COG0110	maltose O-acetyltransferase activity
BFW97_RS07565	COG0297	glycogen (starch) synthase activity
BFW97_RS07570	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BFW97_RS07575	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW97_RS07585	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BFW97_RS07585	COG0662	Cupin 2, conserved barrel domain protein
BFW97_RS07600	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BFW97_RS07605	COG1091	dTDP-4-dehydrorhamnose reductase activity
BFW97_RS07610	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BFW97_RS07620	COG3765	Modulates the polysaccharide chain length of enterobacterial common antigen (ECA)
BFW97_RS07650	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_RS07660	COG3132	Protein of unknown function, DUF480
BFW97_RS07700	COG1278	Cold shock
BFW97_RS07730	COG0697	spore germination
BFW97_RS07735	COG1349	DNA-binding transcription factor activity
BFW97_RS07740	COG1882	Formate acetyltransferase
BFW97_RS07745	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_RS07750	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BFW97_RS07780	COG0622	Phosphoesterase
BFW97_RS07795	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BFW97_RS07800	COG0835	chemotaxis
BFW97_RS07800	COG0784	Response regulator, receiver
BFW97_RS07805	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BFW97_RS07810	COG1815	bacterial-type flagellum-dependent cell motility
BFW97_RS07830	COG4787	bacterial-type flagellum-dependent cell motility
BFW97_RS07840	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BFW97_RS07845	COG1706	bacterial-type flagellum-dependent cell motility
BFW97_RS07855	COG1256	bacterial-type flagellum assembly
BFW97_RS07865	COG2239	Acts as a magnesium transporter
BFW97_RS07875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BFW97_RS07880	COG2716	regulation of RNA biosynthetic process
BFW97_RS07905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BFW97_RS07910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BFW97_RS07915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BFW97_RS07920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BFW97_RS07940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BFW97_RS07950	COG0590	tRNA wobble adenosine to inosine editing
BFW97_RS07955	COG0573	inorganic phosphate transmembrane transporter activity
BFW97_RS07960	COG0581	inorganic phosphate transmembrane transporter activity
BFW97_RS07965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BFW97_RS07970	COG0704	Plays a role in the regulation of phosphate uptake
BFW97_RS07975	COG1253	flavin adenine dinucleotide binding
BFW97_RS07990	COG0531	amino acid
BFW97_RS08005	COG1126	abc transporter atp-binding protein
BFW97_RS08010	COG0765	amino acid transport
BFW97_RS08015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS08025	COG2271	Major facilitator Superfamily
BFW97_RS08040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW97_RS08065	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BFW97_RS08070	COG0477	Major facilitator Superfamily
BFW97_RS08075	COG0123	including yeast histone deacetylase and acetoin utilization protein
BFW97_RS08085	COG1199	ATP-dependent helicase activity
BFW97_RS08100	COG1448	Aminotransferase
BFW97_RS08105	COG0433	COG0433 Predicted ATPase
BFW97_RS08180	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW97_RS08190	COG1522	sequence-specific DNA binding
BFW97_RS08230	COG5642	Protein of unknown function (DUF2384)
BFW97_RS08245	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_RS08300	COG1663	tetraacyldisaccharide 4'-kinase activity
BFW97_RS08305	COG2835	tetraacyldisaccharide 4'-kinase activity
BFW97_RS08310	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BFW97_RS08315	COG2197	response regulator
BFW97_RS08320	COG0322	excinuclease ABC activity
BFW97_RS08345	COG0582	viral genome integration into host DNA
BFW97_RS08395	COG3962	Belongs to the TPP enzyme family
BFW97_RS08405	COG0673	inositol 2-dehydrogenase activity
BFW97_RS08410	COG1879	ABC-type sugar transport system periplasmic component
BFW97_RS08420	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW97_RS08425	COG0673	inositol 2-dehydrogenase activity
BFW97_RS08430	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_RS08440	COG3718	enzyme involved in inositol metabolism
BFW97_RS08535	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BFW97_RS08540	COG0437	4 iron, 4 sulfur cluster binding
BFW97_RS08545	COG3301	Polysulphide reductase, NrfD
BFW97_RS08550	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_RS08560	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFW97_RS08565	COG0215	cysteine-tRNA ligase activity
BFW97_RS08580	COG2199	diguanylate cyclase activity
BFW97_RS08580	COG2203	Gaf domain
BFW97_RS08610	COG2119	membrane
BFW97_RS08615	COG0023	Translation Initiation Factor
BFW97_RS08640	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW97_RS08655	COG2205	protein histidine kinase activity
BFW97_RS08655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS08665	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BFW97_RS08675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_RS08680	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BFW97_RS08685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW97_RS08690	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFW97_RS08695	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BFW97_RS08700	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BFW97_RS08710	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BFW97_RS08715	COG0505	Belongs to the CarA family
BFW97_RS08720	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BFW97_RS08725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW97_RS08755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW97_RS08760	COG0513	Belongs to the DEAD box helicase family
BFW97_RS08770	COG4104	PAAR repeat-containing protein
BFW97_RS08785	COG0789	Transcriptional regulator
BFW97_RS08800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS08805	COG0765	amino acid transport
BFW97_RS08810	COG1126	abc transporter atp-binding protein
BFW97_RS08815	COG0493	'glutamate synthase
BFW97_RS08820	COG0067	glutamate synthase
BFW97_RS08820	COG0069	glutamate synthase activity
BFW97_RS08820	COG0070	glutamate synthase
BFW97_RS08825	COG1242	4 iron, 4 sulfur cluster binding
BFW97_RS08880	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BFW97_RS08885	COG0574	Belongs to the PEP-utilizing enzyme family
BFW97_RS08885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BFW97_RS08920	COG3038	cytochrome b561
BFW97_RS08935	COG1464	Belongs to the NlpA lipoprotein family
BFW97_RS08940	COG0671	phosphoesterase, PA-phosphatase related
BFW97_RS08945	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BFW97_RS08950	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFW97_RS08960	COG0101	tRNA pseudouridine synthase activity
BFW97_RS08965	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BFW97_RS08970	COG0285	dihydrofolate synthase activity
BFW97_RS08975	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BFW97_RS08980	COG2920	part of a sulfur-relay system
BFW97_RS08985	COG1289	transmembrane transporter activity
BFW97_RS08990	COG0670	Belongs to the BI1 family
BFW97_RS09010	COG2194	sulfuric ester hydrolase activity
BFW97_RS09020	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BFW97_RS09020	COG0392	lysyltransferase activity
BFW97_RS09030	COG0840	transmembrane signaling receptor activity
BFW97_RS09035	COG5001	Diguanylate cyclase
BFW97_RS09040	COG0564	pseudouridine synthase activity
BFW97_RS09055	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BFW97_RS09065	COG0625	glutathione transferase activity
BFW97_RS09070	COG0625	glutathione transferase activity
BFW97_RS09080	COG0367	asparagine synthase
BFW97_RS09090	COG4651	solute:proton antiporter activity
BFW97_RS09090	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BFW97_RS09095	COG0647	UMP catabolic process
BFW97_RS09100	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFW97_RS09105	COG1902	pentaerythritol trinitrate reductase activity
BFW97_RS09110	COG1253	flavin adenine dinucleotide binding
BFW97_RS09120	COG0247	lactate metabolic process
BFW97_RS09120	COG0277	FAD linked oxidase domain protein
BFW97_RS09130	COG2050	protein possibly involved in aromatic compounds catabolism
BFW97_RS09140	COG2056	Na+-H+ antiporter family
BFW97_RS09145	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW97_RS09160	COG0346	lactoylglutathione lyase activity
BFW97_RS09165	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BFW97_RS09170	COG4660	Part of a membrane complex involved in electron transport
BFW97_RS09175	COG4659	FMN binding
BFW97_RS09180	COG4658	electron transport chain
BFW97_RS09190	COG2878	Part of a membrane complex involved in electron transport
BFW97_RS09195	COG4657	Part of a membrane complex involved in electron transport
BFW97_RS09200	COG0697	spore germination
BFW97_RS09220	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BFW97_RS09225	COG1288	antiporter activity
BFW97_RS09230	COG0436	Aminotransferase
BFW97_RS09240	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BFW97_RS09245	COG2027	D-alanyl-D-alanine carboxypeptidase
BFW97_RS09250	COG1061	Type III restriction enzyme res subunit
BFW97_RS09255	COG1566	PFAM secretion protein HlyD family protein
BFW97_RS09265	COG1966	Carbon starvation protein
BFW97_RS09270	COG3279	Response regulator of the LytR AlgR family
BFW97_RS09275	COG3275	phosphorelay sensor kinase activity
BFW97_RS09280	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_RS09280	COG2199	diguanylate cyclase activity
BFW97_RS09285	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_RS09285	COG1454	alcohol dehydrogenase
BFW97_RS09295	COG2095	MarC family integral membrane protein
BFW97_RS09305	COG0601	transmembrane transport
BFW97_RS09310	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_RS09330	COG0861	Integral membrane protein TerC family
BFW97_RS09335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW97_RS09345	COG1301	dicarboxylic acid transport
BFW97_RS09360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BFW97_RS09375	COG0537	adenosine 5'-monophosphoramidase activity
BFW97_RS09410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_RS09415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_RS09425	COG2354	Protein conserved in bacteria
BFW97_RS09440	COG2233	PERMEase
BFW97_RS09445	COG3150	esterase
BFW97_RS09450	COG1252	NADH dehydrogenase
BFW97_RS09470	COG0393	Putative heavy-metal-binding
BFW97_RS09480	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BFW97_RS09480	COG1648	precorrin-2 dehydrogenase activity
BFW97_RS09500	COG4667	esterase of the alpha-beta hydrolase superfamily
BFW97_RS09505	COG1619	proteins homologs of microcin C7 resistance protein MccF
BFW97_RS09510	COG1368	sulfuric ester hydrolase activity
BFW97_RS09520	COG0527	aspartate kinase activity
BFW97_RS09525	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BFW97_RS09525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW97_RS09530	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW97_RS09555	COG0596	Alpha beta hydrolase
BFW97_RS09560	COG0346	lactoylglutathione lyase activity
BFW97_RS09570	COG0583	DNA-binding transcription factor activity
BFW97_RS09575	COG1620	l-lactate permease
BFW97_RS09585	COG1139	Iron-sulfur cluster binding protein
BFW97_RS09610	COG0577	efflux transmembrane transporter activity
BFW97_RS09615	COG1136	(ABC) transporter
BFW97_RS09625	COG2814	Major facilitator Superfamily
BFW97_RS09645	COG0672	)-iron permease
BFW97_RS09675	COG0659	secondary active sulfate transmembrane transporter activity
BFW97_RS09715	COG4771	TonB-dependent receptor
BFW97_RS09715	COG1629	transport
BFW97_RS09745	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW97_RS09750	COG0840	transmembrane signaling receptor activity
BFW97_RS09760	COG2201	protein-glutamate methylesterase activity
BFW97_RS09770	COG0835	chemotaxis
BFW97_RS09775	COG3290	protein histidine kinase activity
BFW97_RS09775	COG0840	transmembrane signaling receptor activity
BFW97_RS09780	COG2198	Histidine kinase
BFW97_RS09780	COG0643	Histidine kinase
BFW97_RS09790	COG0745	RESPONSE REGULATOR receiver
BFW97_RS09795	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BFW97_RS09800	COG0437	4 iron, 4 sulfur cluster binding
BFW97_RS09805	COG5557	Pfam Polysulphide reductase, NrfD
BFW97_RS09810	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BFW97_RS09815	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BFW97_RS09820	COG1773	rubredoxin
BFW97_RS09825	COG0747	negative chemotaxis
BFW97_RS09830	COG0601	transmembrane transport
BFW97_RS09835	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_RS09840	COG0444	Belongs to the ABC transporter superfamily
BFW97_RS09845	COG3842	ATPase activity
BFW97_RS09850	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BFW97_RS09855	COG0375	protein maturation
BFW97_RS09860	COG0309	Hydrogenase expression formation protein (HypE)
BFW97_RS09870	COG0298	carbon dioxide binding
BFW97_RS09875	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BFW97_RS09885	COG1921	L-seryl-tRNASec selenium transferase activity
BFW97_RS09890	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BFW97_RS09900	COG3260	NADH ubiquinone oxidoreductase 20
BFW97_RS09905	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_RS09910	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BFW97_RS09910	COG3261	NADH dehydrogenase
BFW97_RS09915	COG0650	Formate hydrogenlyase subunit 4
BFW97_RS09920	COG0651	ATP synthesis coupled electron transport
BFW97_RS09925	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_RS09930	COG3158	transport of potassium into the cell
BFW97_RS09945	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_RS09970	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BFW97_RS09975	COG0326	Molecular chaperone. Has ATPase activity
BFW97_RS09985	COG0563	adenylate kinase activity
BFW97_RS09990	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BFW97_RS10000	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_RS10020	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BFW97_RS10040	COG1021	2,3-dihydroxybenzoate-AMP ligase
BFW97_RS10045	COG1535	isochorismatase
BFW97_RS10045	COG3433	isochorismatase activity
BFW97_RS10050	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFW97_RS10055	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_RS10065	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BFW97_RS10070	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BFW97_RS10075	COG2977	Belongs to the P-Pant transferase superfamily
BFW97_RS10080	COG1120	ATPase activity
BFW97_RS10085	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_RS10090	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_RS10095	COG4771	TonB-dependent receptor
BFW97_RS10140	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BFW97_RS10145	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BFW97_RS10150	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_RS10165	COG1570	exodeoxyribonuclease VII activity
BFW97_RS10170	COG0697	spore germination
BFW97_RS10190	COG3158	transport of potassium into the cell
BFW97_RS10195	COG0517	IMP dehydrogenase activity
BFW97_RS10195	COG0516	GMP reductase activity
BFW97_RS10200	COG0519	Catalyzes the synthesis of GMP from XMP
BFW97_RS10200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW97_RS10210	COG0582	viral genome integration into host DNA
BFW97_RS10280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFW97_RS10280	COG2169	Transcriptional regulator
BFW97_RS10305	COG2062	phosphohistidine phosphatase, SixA
BFW97_RS10315	COG0697	spore germination
BFW97_RS10320	COG4166	transmembrane transport
BFW97_RS10325	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BFW97_RS10330	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BFW97_RS10340	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFW97_RS10345	COG1136	(ABC) transporter
BFW97_RS10350	COG4591	ABC-type transport system involved in lipoprotein release permease component
BFW97_RS10355	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BFW97_RS10370	COG0544	peptidyl-prolyl cis-trans isomerase activity
BFW97_RS10375	COG0740	serine-type endopeptidase activity
BFW97_RS10380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BFW97_RS10385	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BFW97_RS10390	COG0776	regulation of translation
BFW97_RS10395	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW97_RS10400	COG0488	(ABC) transporter
BFW97_RS10405	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW97_RS10410	COG3162	membrane
BFW97_RS10425	COG1024	Enoyl-CoA hydratase
BFW97_RS10465	COG1115	amino acid carrier protein
BFW97_RS10480	COG1584	GPR1 FUN34 yaaH family protein
BFW97_RS10515	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BFW97_RS10520	COG1960	acyl-CoA dehydrogenase activity
BFW97_RS10530	COG1960	acyl-CoA dehydrogenase activity
BFW97_RS10535	COG1024	Enoyl-CoA hydratase
BFW97_RS10540	COG1024	Enoyl-CoA hydratase
BFW97_RS10550	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_RS10560	COG0730	response to heat
BFW97_RS10585	COG5001	Diguanylate cyclase
BFW97_RS10585	COG5002	protein histidine kinase activity
BFW97_RS10600	COG2003	Belongs to the UPF0758 family
BFW97_RS10610	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BFW97_RS10640	COG1073	alpha beta
BFW97_RS10645	COG0823	Involved in the tonB-independent uptake of proteins
BFW97_RS10645	COG1506	peptidase
BFW97_RS10650	COG0702	epimerase
BFW97_RS10655	COG0583	DNA-binding transcription factor activity
BFW97_RS10660	COG0667	Aldo Keto reductase
BFW97_RS10675	COG3706	GGDEF domain
BFW97_RS10680	COG0583	DNA-binding transcription factor activity
BFW97_RS10685	COG2723	6-phospho-beta-galactosidase activity
BFW97_RS10690	COG5001	Diguanylate cyclase
BFW97_RS10690	COG3300	MHYT domain
BFW97_RS10700	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_RS10705	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_RS10710	COG0583	DNA-binding transcription factor activity
BFW97_RS10715	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BFW97_RS10720	COG0673	inositol 2-dehydrogenase activity
BFW97_RS10725	COG0583	DNA-binding transcription factor activity
BFW97_RS10735	COG1560	Kdo2-lipid A biosynthetic process
BFW97_RS10740	COG1560	Kdo2-lipid A biosynthetic process
BFW97_RS10770	COG0417	DNA replication proofreading
BFW97_RS10800	COG0534	Mate efflux family protein
BFW97_RS10810	COG0307	riboflavin synthase, alpha
BFW97_RS10820	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_RS10825	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BFW97_RS10830	COG0697	spore germination
BFW97_RS10835	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BFW97_RS10875	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BFW97_RS10880	COG3099	Belongs to the UPF0263 family
BFW97_RS10885	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BFW97_RS10890	COG2894	cell division
BFW97_RS10895	COG0850	regulation of cytokinetic process
BFW97_RS10900	COG3100	YcgL domain-containing protein
BFW97_RS10905	COG2951	lytic endotransglycosylase activity
BFW97_RS10910	COG1760	l-serine dehydratase
BFW97_RS10920	COG1760	l-serine dehydratase
BFW97_RS10925	COG3123	guanosine phosphorylase activity
BFW97_RS10945	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BFW97_RS10965	COG1595	DNA-templated transcription, initiation
BFW97_RS10995	COG0714	Associated with various cellular activities
BFW97_RS11000	COG0183	Belongs to the thiolase family
BFW97_RS11005	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW97_RS11005	COG1024	Enoyl-CoA hydratase
BFW97_RS11050	COG4388	Caudovirus prohead serine protease
BFW97_RS11055	COG3829	transcription factor binding
BFW97_RS11060	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BFW97_RS11065	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BFW97_RS11070	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW97_RS11080	COG0549	Belongs to the carbamate kinase family
BFW97_RS11085	COG0697	spore germination
BFW97_RS11090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BFW97_RS11090	COG3608	succinylglutamate desuccinylase aspartoacylase
BFW97_RS11095	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BFW97_RS11100	COG2068	MobA-Related Protein
BFW97_RS11105	COG0493	'glutamate synthase
BFW97_RS11105	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_RS11110	COG0402	S-adenosylhomocysteine deaminase activity
BFW97_RS11115	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BFW97_RS11120	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFW97_RS11120	COG2080	2 iron, 2 sulfur cluster binding
BFW97_RS11125	COG2233	PERMEase
BFW97_RS11130	COG0402	S-adenosylhomocysteine deaminase activity
BFW97_RS11135	COG2252	PERMEase
BFW97_RS11140	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BFW97_RS11145	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BFW97_RS11150	COG2080	2 iron, 2 sulfur cluster binding
BFW97_RS11160	COG3134	Outer membrane lipoprotein
BFW97_RS11170	COG1288	antiporter activity
BFW97_RS11175	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_RS11180	COG0140	phosphoribosyl-ATP diphosphatase activity
BFW97_RS11180	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BFW97_RS11185	COG0107	imidazoleglycerol-phosphate synthase activity
BFW97_RS11190	COG0784	Response regulator, receiver
BFW97_RS11190	COG2198	Histidine kinase
BFW97_RS11190	COG2205	protein histidine kinase activity
BFW97_RS11195	COG2199	diguanylate cyclase activity
BFW97_RS11200	COG3437	response regulator, receiver
BFW97_RS11205	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BFW97_RS11210	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BFW97_RS11215	COG0131	Imidazoleglycerol-phosphate dehydratase
BFW97_RS11215	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BFW97_RS11220	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BFW97_RS11225	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BFW97_RS11230	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BFW97_RS11240	COG1199	ATP-dependent helicase activity
BFW97_RS11250	COG1214	PFAM Peptidase M22, glycoprotease
BFW97_RS11260	COG2226	methyltransferase
BFW97_RS11260	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BFW97_RS11260	COG0596	Alpha beta hydrolase
BFW97_RS11265	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_RS11270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BFW97_RS11390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BFW97_RS11400	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BFW97_RS11405	COG2832	Protein of unknown function (DUF454)
BFW97_RS11410	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BFW97_RS11420	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BFW97_RS11425	COG0582	viral genome integration into host DNA
BFW97_RS11455	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BFW97_RS11555	COG0753	catalase activity
BFW97_RS11610	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFW97_RS11615	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFW97_RS11630	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_RS11800	COG0517	IMP dehydrogenase activity
BFW97_RS11800	COG0617	tRNA 3'-terminal CCA addition
BFW97_RS11800	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BFW97_RS11805	COG1643	Atp-dependent helicase
BFW97_RS11815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BFW97_RS11825	COG3437	response regulator, receiver
BFW97_RS11830	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFW97_RS11835	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BFW97_RS11840	COG0709	Synthesizes selenophosphate from selenide and ATP
BFW97_RS11860	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFW97_RS11865	COG0840	transmembrane signaling receptor activity
BFW97_RS11870	COG1254	Belongs to the acylphosphatase family
BFW97_RS11875	COG0625	glutathione transferase activity
BFW97_RS11880	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_RS11880	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_RS11885	COG0489	protein tyrosine kinase activity
BFW97_RS11890	COG0572	uridine kinase
BFW97_RS11895	COG0717	Belongs to the dCTP deaminase family
BFW97_RS11905	COG0306	phosphate transporter
BFW97_RS11910	COG1530	ribonuclease E activity
BFW97_RS11915	COG0564	pseudouridine synthase activity
BFW97_RS11925	COG0424	maF-like protein
BFW97_RS11930	COG2814	Major facilitator Superfamily
BFW97_RS11945	COG1399	metal-binding, possibly nucleic acid-binding protein
BFW97_RS11950	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BFW97_RS11955	COG0416	fatty acid biosynthetic process
BFW97_RS11960	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFW97_RS11970	COG1028	Short-chain dehydrogenase reductase Sdr
BFW97_RS11975	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BFW97_RS11985	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BFW97_RS11990	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BFW97_RS11995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BFW97_RS12000	COG0470	DNA polymerase III
BFW97_RS12005	COG0084	hydrolase, TatD family'
BFW97_RS12020	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BFW97_RS12020	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW97_RS12025	COG3008	intermembrane lipid transfer
BFW97_RS12030	COG2995	paraquat-inducible protein a
BFW97_RS12040	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BFW97_RS12045	COG0372	Belongs to the citrate synthase family
BFW97_RS12090	COG4221	oxidoreductase activity
BFW97_RS12100	COG3141	response to X-ray
BFW97_RS12110	COG1067	ATP-dependent peptidase activity
BFW97_RS12115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFW97_RS12130	COG0488	(ABC) transporter
BFW97_RS12140	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BFW97_RS12140	COG0116	Belongs to the methyltransferase superfamily
BFW97_RS12150	COG0167	dihydroorotate dehydrogenase activity
BFW97_RS12155	COG2902	Dehydrogenase
BFW97_RS12165	COG0308	aminopeptidase N
BFW97_RS12175	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BFW97_RS12180	COG1956	GAF domain-containing protein
BFW97_RS12190	COG3278	Belongs to the heme-copper respiratory oxidase family
BFW97_RS12205	COG2010	Cytochrome c
BFW97_RS12230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW97_RS12235	COG0589	response to stress
BFW97_RS12240	COG0037	tRNA processing
BFW97_RS12255	COG0625	glutathione transferase activity
BFW97_RS12260	COG1869	D-ribose catabolic process
BFW97_RS12265	COG1129	ABC transporter
BFW97_RS12270	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW97_RS12275	COG1879	ABC-type sugar transport system periplasmic component
BFW97_RS12280	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_RS12285	COG1609	Transcriptional regulator
BFW97_RS12320	COG0776	regulation of translation
BFW97_RS12325	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_RS12325	COG0072	phenylalanine-tRNA ligase activity
BFW97_RS12330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BFW97_RS12335	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BFW97_RS12340	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BFW97_RS12345	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BFW97_RS12350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BFW97_RS12370	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFW97_RS12380	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW97_RS12385	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW97_RS12390	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW97_RS12395	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BFW97_RS12400	COG3313	Fe-S protein
BFW97_RS12405	COG2942	2-epimerase
BFW97_RS12410	COG3716	PTS system mannose fructose sorbose family IID component
BFW97_RS12415	COG3715	PTS system
BFW97_RS12420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS12420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS12435	COG1609	Transcriptional regulator
BFW97_RS12440	COG2140	Oxalate decarboxylase
BFW97_RS12445	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_RS12445	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BFW97_RS12445	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_RS12450	COG1105	Belongs to the carbohydrate kinase PfkB family
BFW97_RS12455	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS12455	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS12460	COG1609	Transcriptional regulator
BFW97_RS12465	COG0814	amino acid
BFW97_RS12475	COG5654	RES domain protein
BFW97_RS12485	COG0513	Belongs to the DEAD box helicase family
BFW97_RS12495	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BFW97_RS12500	COG2890	protein-(glutamine-N5) methyltransferase activity
BFW97_RS12505	COG2840	Smr protein MutS2
BFW97_RS12515	COG3706	GGDEF domain
BFW97_RS12520	COG0588	phosphoglycerate mutase activity
BFW97_RS12545	COG2824	Alkylphosphonate utilization operon protein PhnA
BFW97_RS12565	COG0384	phenazine biosynthesis protein PhzF
BFW97_RS12580	COG0242	peptide deformylase activity
BFW97_RS12600	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BFW97_RS12605	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BFW97_RS12615	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BFW97_RS12620	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BFW97_RS12630	COG0205	6-phosphofructokinase activity
BFW97_RS12635	COG1473	amidohydrolase
BFW97_RS12640	COG1011	Hydrolase
BFW97_RS12645	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW97_RS12695	COG3593	DNA synthesis involved in DNA repair
BFW97_RS12710	COG0583	DNA-binding transcription factor activity
BFW97_RS12715	COG0730	response to heat
BFW97_RS12720	COG3148	PFAM DTW domain containing protein
BFW97_RS12730	COG1181	Belongs to the D-alanine--D-alanine ligase family
BFW97_RS12740	COG0386	Belongs to the glutathione peroxidase family
BFW97_RS12745	COG0513	Belongs to the DEAD box helicase family
BFW97_RS12750	COG0456	acetyltransferase
BFW97_RS12760	COG1742	UPF0060 membrane protein
BFW97_RS12790	COG2329	Antibiotic biosynthesis monooxygenase
BFW97_RS12795	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BFW97_RS12815	COG3243	poly(R)-hydroxyalkanoic acid synthase
BFW97_RS12825	COG2501	S4 domain
BFW97_RS12840	COG1132	(ABC) transporter
BFW97_RS12850	COG1132	(ABC) transporter
BFW97_RS12860	COG3118	belongs to the thioredoxin family
BFW97_RS12865	COG0471	metal ion transport
BFW97_RS12870	COG0058	SHG alpha-glucan phosphorylase activity
BFW97_RS12905	COG0814	amino acid
BFW97_RS12910	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BFW97_RS12915	COG0514	ATP-dependent DNA helicase (RecQ)
BFW97_RS12920	COG2766	serine protein kinase
BFW97_RS12930	COG2719	SpoVR family
BFW97_RS12935	COG2186	Transcriptional regulator
BFW97_RS12940	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW97_RS12945	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BFW97_RS12950	COG0586	Pfam SNARE associated Golgi protein
BFW97_RS12960	COG0556	nucleotide-excision repair
BFW97_RS12975	COG2985	domain, Protein
BFW97_RS12975	COG0569	domain protein
BFW97_RS12980	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFW97_RS13055	COG1522	sequence-specific DNA binding
BFW97_RS13110	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_RS13170	COG4565	transcriptional regulatory protein
BFW97_RS13175	COG3290	protein histidine kinase activity
BFW97_RS13180	COG1846	Transcriptional regulator
BFW97_RS13180	COG1940	carbohydrate kinase activity
BFW97_RS13185	COG0840	transmembrane signaling receptor activity
BFW97_RS13190	COG3012	SEC-C Motif Domain Protein
BFW97_RS13195	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BFW97_RS13200	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BFW97_RS13205	COG0247	lactate metabolic process
BFW97_RS13225	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BFW97_RS13230	COG0437	4 iron, 4 sulfur cluster binding
BFW97_RS13235	COG3301	Polysulphide reductase, NrfD
BFW97_RS13240	COG1138	Cytochrome C-type biogenesis protein
BFW97_RS13250	COG4235	cytochrome complex assembly
BFW97_RS13250	COG3088	subunit of a heme lyase
BFW97_RS13255	COG1051	belongs to the nudix hydrolase family
BFW97_RS13265	COG3033	Beta-eliminating lyase
BFW97_RS13275	COG3046	protein related to deoxyribodipyrimidine photolyase
BFW97_RS13280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_RS13305	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BFW97_RS13310	COG0583	DNA-binding transcription factor activity
BFW97_RS13320	COG4774	siderophore transport
BFW97_RS13325	COG4977	sequence-specific DNA binding
BFW97_RS13335	COG0583	DNA-binding transcription factor activity
BFW97_RS13340	COG2910	NAD(P)H-binding
BFW97_RS13350	COG0626	cystathionine gamma-synthase activity
BFW97_RS13355	COG0612	Peptidase, M16
BFW97_RS13360	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BFW97_RS13370	COG1944	ATP diphosphatase activity
BFW97_RS13375	COG2116	formate transmembrane transporter activity
BFW97_RS13380	COG1882	Formate acetyltransferase
BFW97_RS13385	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BFW97_RS13395	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BFW97_RS13405	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW97_RS13410	COG3842	ATPase activity
BFW97_RS13420	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_RS13425	COG2983	Belongs to the UPF0260 family
BFW97_RS13440	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BFW97_RS13445	COG0045	succinate-CoA ligase (ADP-forming) activity
BFW97_RS13450	COG0508	dehydrogenase complex catalyzes the overall conversion of
BFW97_RS13455	COG0567	Dehydrogenase, E1 component
BFW97_RS13465	COG1053	succinate dehydrogenase
BFW97_RS13470	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BFW97_RS13495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BFW97_RS13500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_RS13500	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BFW97_RS13510	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW97_RS13525	COG1451	nucleotide metabolic process
BFW97_RS13540	COG0254	rRNA binding
BFW97_RS13545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFW97_RS13555	COG0583	DNA-binding transcription factor activity
BFW97_RS13565	COG1172	Belongs to the binding-protein-dependent transport system permease family
BFW97_RS13575	COG1879	ABC-type sugar transport system periplasmic component
BFW97_RS13580	COG1069	ribulokinase activity
BFW97_RS13590	COG2160	L-arabinose isomerase activity
BFW97_RS13595	COG2925	Exonuclease
BFW97_RS13605	COG3345	alpha-galactosidase
BFW97_RS13610	COG1380	Effector of murein hydrolase LrgA
BFW97_RS13615	COG1346	cytolysis
BFW97_RS13620	COG0295	cytidine deaminase activity
BFW97_RS13625	COG1022	Amp-dependent synthetase and ligase
BFW97_RS13640	COG0861	Integral membrane protein TerC family
BFW97_RS13645	COG2885	chlorophyll binding
BFW97_RS13650	COG2199	diguanylate cyclase activity
BFW97_RS13670	COG2154	pterin-4-alpha-carbinolamine dehydratase
BFW97_RS13680	COG3768	UPF0283 membrane protein
BFW97_RS13685	COG3106	COG3106 Predicted ATPase
BFW97_RS13700	COG1842	Phage shock protein A
BFW97_RS13705	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BFW97_RS13715	COG4168	peptide transport system, permease
BFW97_RS13720	COG4171	peptide transport system, permease
BFW97_RS13730	COG4172	Belongs to the ABC transporter superfamily
BFW97_RS13740	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BFW97_RS13745	COG1286	toxin biosynthetic process
BFW97_RS13750	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BFW97_RS13760	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BFW97_RS13765	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BFW97_RS13770	COG0531	amino acid
BFW97_RS13770	COG1674	ftsk spoiiie
BFW97_RS13780	COG0686	Belongs to the AlaDH PNT family
BFW97_RS13785	COG0492	ferredoxin-NADP+ reductase activity
BFW97_RS13790	COG3706	GGDEF domain
BFW97_RS13795	COG3134	Outer membrane lipoprotein
BFW97_RS13800	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BFW97_RS13805	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BFW97_RS13810	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BFW97_RS13815	COG0542	response to heat
BFW97_RS13820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BFW97_RS13825	COG1278	Cold shock
BFW97_RS13830	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BFW97_RS13895	COG3829	transcription factor binding
BFW97_RS13970	COG3501	Rhs element vgr protein
BFW97_RS14000	COG1435	thymidine kinase activity
BFW97_RS14005	COG1757	Na H antiporter
BFW97_RS14010	COG2916	Histone family protein nucleoid-structuring protein H-NS
BFW97_RS14015	COG2096	Adenosyltransferase
BFW97_RS14020	COG3530	Putative quorum-sensing-regulated virulence factor
BFW97_RS14025	COG0602	queuosine metabolic process
BFW97_RS14030	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFW97_RS14050	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BFW97_RS14060	COG0776	regulation of translation
BFW97_RS14065	COG0539	negative regulation of cytoplasmic translation
BFW97_RS14070	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BFW97_RS14075	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFW97_RS14085	COG0583	DNA-binding transcription factor activity
BFW97_RS14105	COG0778	Nitroreductase
BFW97_RS14110	COG5001	Diguanylate cyclase
BFW97_RS14110	COG3300	MHYT domain
BFW97_RS14120	COG0583	DNA-binding transcription factor activity
BFW97_RS14125	COG3437	response regulator, receiver
BFW97_RS14150	COG4989	oxidoreductase activity
BFW97_RS14155	COG0724	RNA recognition motif
BFW97_RS14175	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BFW97_RS14190	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW97_RS14195	COG1360	Flagellar Motor Protein
BFW97_RS14200	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_RS14205	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_RS14210	COG0649	NAD binding
BFW97_RS14210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_RS14225	COG1034	ATP synthesis coupled electron transport
BFW97_RS14230	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BFW97_RS14235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_RS14240	COG0839	Belongs to the complex I subunit 6 family
BFW97_RS14245	COG0713	ATP synthesis coupled electron transport
BFW97_RS14255	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BFW97_RS14260	COG1007	ATP synthesis coupled electron transport
BFW97_RS14270	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BFW97_RS14270	COG0047	phosphoribosylformylglycinamidine synthase activity
BFW97_RS14275	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BFW97_RS14285	COG1645	bacterial-type flagellum-dependent swarming motility
BFW97_RS14290	COG1160	GTP binding
BFW97_RS14295	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_RS14300	COG2976	Protein conserved in bacteria
BFW97_RS14305	COG0124	histidyl-tRNA synthetase
BFW97_RS14310	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BFW97_RS14325	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BFW97_RS14330	COG0105	UTP biosynthetic process
BFW97_RS14335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BFW97_RS14345	COG0633	Ferredoxin
BFW97_RS14350	COG0443	Heat shock 70 kDa protein
BFW97_RS14355	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BFW97_RS14365	COG0822	iron-sulfur transferase activity
BFW97_RS14370	COG1104	cysteine desulfurase activity
BFW97_RS14390	COG3154	lipid carrier protein
BFW97_RS14395	COG0826	peptidase U32
BFW97_RS14400	COG0826	peptidase U32
BFW97_RS14415	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_RS14420	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BFW97_RS14425	COG1862	Preprotein translocase
BFW97_RS14430	COG0343	queuine tRNA-ribosyltransferase activity
BFW97_RS14435	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BFW97_RS14440	COG0517	IMP dehydrogenase activity
BFW97_RS14450	COG3634	alkyl hydroperoxide reductase activity
BFW97_RS14470	COG1393	Belongs to the ArsC family
BFW97_RS14475	COG0798	PFAM Bile acid sodium symporter
BFW97_RS14480	COG0640	Transcriptional regulator
BFW97_RS14485	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW97_RS14485	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BFW97_RS14490	COG0509	glycine decarboxylation via glycine cleavage system
BFW97_RS14495	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BFW97_RS14500	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW97_RS14505	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BFW97_RS14525	COG2814	Major facilitator Superfamily
BFW97_RS14530	COG0625	glutathione transferase activity
BFW97_RS14540	COG0483	inositol monophosphate 1-phosphatase activity
BFW97_RS14560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFW97_RS14575	COG1086	Polysaccharide biosynthesis protein
BFW97_RS14595	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BFW97_RS14605	COG2089	acid synthase
BFW97_RS14680	COG0301	tRNA thio-modification
BFW97_RS14680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW97_RS14690	COG4953	penicillin-binding protein 1C
BFW97_RS14695	COG2373	Large extracellular alpha-helical protein
BFW97_RS14705	COG0628	permease
BFW97_RS14710	COG1538	Outer membrane efflux protein
BFW97_RS14730	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_RS14740	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_RS14760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS14770	COG2431	L-lysine efflux transmembrane transporter activity
BFW97_RS14775	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW97_RS14780	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
BFW97_RS14795	COG1393	Belongs to the ArsC family
BFW97_RS14805	COG4783	chaperone-mediated protein folding
BFW97_RS14810	COG0425	Belongs to the sulfur carrier protein TusA family
BFW97_RS14835	COG3842	ATPase activity
BFW97_RS14840	COG3833	ABC-type maltose transport systems, permease component
BFW97_RS14845	COG1175	transmembrane transport
BFW97_RS14855	COG3081	Nucleoid-associated protein
BFW97_RS14860	COG3082	Protein of unknown function (DUF1414)
BFW97_RS14865	COG3083	sulfuric ester hydrolase activity
BFW97_RS14870	COG4771	TonB-dependent receptor
BFW97_RS14875	COG1770	oligopeptidase
BFW97_RS14895	COG4574	serine-type endopeptidase inhibitor activity
BFW97_RS14900	COG3085	chromosome segregation
BFW97_RS14905	COG0583	DNA-binding transcription factor activity
BFW97_RS14910	COG1605	Chorismate mutase
BFW97_RS14910	COG0287	Prephenate dehydrogenase
BFW97_RS14915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BFW97_RS14920	COG0584	glycerophosphoryl diester phosphodiesterase
BFW97_RS14935	COG1349	DNA-binding transcription factor activity
BFW97_RS14940	COG2271	Major facilitator Superfamily
BFW97_RS14945	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFW97_RS14950	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BFW97_RS14955	COG0583	DNA-binding transcription factor activity
BFW97_RS14975	COG0656	L-ascorbic acid biosynthetic process
BFW97_RS14980	COG2814	Major facilitator Superfamily
BFW97_RS14990	COG1294	oxidase, subunit
BFW97_RS15000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BFW97_RS15010	COG2979	Protein of unknown function (DUF533)
BFW97_RS15035	COG2271	Major facilitator Superfamily
BFW97_RS15040	COG0583	DNA-binding transcription factor activity
BFW97_RS15050	COG2807	transmembrane transport
BFW97_RS15055	COG1187	pseudouridine synthase activity
BFW97_RS15085	COG1061	Type III restriction enzyme res subunit
BFW97_RS15095	COG2964	Protein conserved in bacteria
BFW97_RS15100	COG3681	Belongs to the UPF0597 family
BFW97_RS15110	COG0814	amino acid
BFW97_RS15130	COG1166	arginine decarboxylase activity
BFW97_RS15150	COG2195	Cleaves the N-terminal amino acid of tripeptides
BFW97_RS15180	COG0583	DNA-binding transcription factor activity
BFW97_RS15190	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BFW97_RS15195	COG0840	transmembrane signaling receptor activity
BFW97_RS15200	COG0302	gtp cyclohydrolase
BFW97_RS15210	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFW97_RS15220	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BFW97_RS15235	COG0314	molybdopterin synthase activity
BFW97_RS15240	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BFW97_RS15245	COG0315	cyclic pyranopterin monophosphate synthase activity
BFW97_RS15250	COG0521	Mo-molybdopterin cofactor biosynthetic process
BFW97_RS15255	COG3005	denitrification pathway
BFW97_RS15265	COG0348	domain, Protein
BFW97_RS15270	COG0437	4 iron, 4 sulfur cluster binding
BFW97_RS15275	COG0243	molybdopterin cofactor binding
BFW97_RS15285	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_RS15285	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_RS15290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BFW97_RS15295	COG3850	Histidine kinase
BFW97_RS15300	COG2197	response regulator
BFW97_RS15330	COG0121	glutamine amidotransferase
BFW97_RS15335	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BFW97_RS15340	COG1960	acyl-CoA dehydrogenase activity
BFW97_RS15345	COG3437	response regulator, receiver
BFW97_RS15345	COG0784	Response regulator, receiver
BFW97_RS15360	COG0328	RNA-DNA hybrid ribonuclease activity
BFW97_RS15365	COG2226	methyltransferase
BFW97_RS15370	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BFW97_RS15375	COG1388	LysM domain
BFW97_RS15375	COG0741	lytic transglycosylase activity
BFW97_RS15380	COG3021	interspecies interaction between organisms
BFW97_RS15390	COG1607	acyl-coa hydrolase
BFW97_RS15405	COG0741	lytic transglycosylase activity
BFW97_RS15415	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BFW97_RS15440	COG0729	surface antigen
BFW97_RS15450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BFW97_RS15455	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BFW97_RS15465	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BFW97_RS15475	COG4134	Bacterial extracellular solute-binding protein
BFW97_RS15485	COG4136	ATPase activity
BFW97_RS15490	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BFW97_RS15495	COG2951	lytic endotransglycosylase activity
BFW97_RS15500	COG1846	Transcriptional regulator
BFW97_RS15510	COG0033	Phosphoglucomutase
BFW97_RS15515	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BFW97_RS15520	COG0596	Alpha beta hydrolase
BFW97_RS15535	COG0716	FMN binding
BFW97_RS15545	COG0735	belongs to the Fur family
BFW97_RS15550	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BFW97_RS15565	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS15565	COG1263	PTS System
BFW97_RS15565	COG2190	(PTS) system
BFW97_RS15570	COG0363	glucosamine-6-phosphate deaminase activity
BFW97_RS15575	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW97_RS15580	COG1940	carbohydrate kinase activity
BFW97_RS15580	COG1846	Transcriptional regulator
BFW97_RS15585	COG2194	sulfuric ester hydrolase activity
BFW97_RS15590	COG0217	transcriptional regulatory protein
BFW97_RS15595	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BFW97_RS15600	COG1801	Protein of unknown function DUF72
BFW97_RS15605	COG4106	trans-aconitate 2-methyltransferase activity
BFW97_RS15610	COG0500	methyltransferase
BFW97_RS15630	COG0450	alkyl hydroperoxide reductase
BFW97_RS15635	COG0583	DNA-binding transcription factor activity
BFW97_RS15645	COG0791	NLP P60 protein
BFW97_RS15660	COG1309	transcriptional regulator
BFW97_RS15700	COG0534	Mate efflux family protein
BFW97_RS15720	COG2366	antibiotic biosynthetic process
BFW97_RS15725	COG0674	pyruvate-flavodoxin oxidoreductase activity
BFW97_RS15725	COG1013	pyruvate-flavodoxin oxidoreductase activity
BFW97_RS15725	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BFW97_RS15725	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BFW97_RS15735	COG0633	Ferredoxin
BFW97_RS15735	COG3217	Mosc domain protein beta barrel domain protein
BFW97_RS15735	COG0633	Ferredoxin
BFW97_RS15735	COG3217	Mosc domain protein beta barrel domain protein
BFW97_RS15745	COG0501	Belongs to the peptidase M48B family
BFW97_RS15750	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BFW97_RS15755	COG1073	alpha beta
BFW97_RS15755	COG2226	methyltransferase
BFW97_RS15760	COG0156	8-amino-7-oxononanoate synthase activity
BFW97_RS15765	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFW97_RS15785	COG0017	Asparaginyl-tRNA synthetase
BFW97_RS15790	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BFW97_RS15805	COG3069	C4-dicarboxylate transmembrane transporter activity
BFW97_RS15815	COG0583	DNA-binding transcription factor activity
BFW97_RS15820	COG1393	Belongs to the ArsC family
BFW97_RS15825	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BFW97_RS15830	COG1876	peptidase activity
BFW97_RS15840	COG3263	regulation of cellular component size
BFW97_RS15860	COG1280	lysine exporter protein (LysE YggA)
BFW97_RS15885	COG1957	nucleoside hydrolase
BFW97_RS15890	COG0564	pseudouridine synthase activity
BFW97_RS15900	COG1454	alcohol dehydrogenase
BFW97_RS15950	COG4964	Belongs to the GSP D family
BFW97_RS15980	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BFW97_RS15985	COG0702	epimerase
BFW97_RS15990	COG2914	Belongs to the UPF0125 (RnfH) family
BFW97_RS15995	COG2867	negative regulation of translational initiation
BFW97_RS16000	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BFW97_RS16085	COG4397	Mu-like prophage major head subunit gpT
BFW97_RS16090	COG4388	Caudovirus prohead serine protease
BFW97_RS16110	COG4383	Mu-like prophage protein gp29
BFW97_RS16115	COG4373	Mu-like prophage FluMu protein gp28
BFW97_RS16125	COG0640	Transcriptional regulator
BFW97_RS16165	COG5566	PFAM Mor transcription activator
BFW97_RS16275	COG0583	DNA-binding transcription factor activity
BFW97_RS16280	COG2610	gluconate transmembrane transporter activity
BFW97_RS16285	COG3048	D-serine ammonia-lyase activity
BFW97_RS16295	COG0538	isocitrate dehydrogenase activity
BFW97_RS16300	COG2207	Transcriptional regulator
BFW97_RS16320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_RS16330	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BFW97_RS16335	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS16335	COG1263	PTS System
BFW97_RS16340	COG1609	Transcriptional regulator
BFW97_RS16355	COG0456	acetyltransferase
BFW97_RS16375	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_RS16375	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS16375	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_RS16385	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BFW97_RS16395	COG1187	pseudouridine synthase activity
BFW97_RS16405	COG0482	sulfurtransferase activity
BFW97_RS16410	COG2915	High frequency lysogenization protein hflD homolog
BFW97_RS16415	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BFW97_RS16420	COG2850	peptidyl-arginine hydroxylation
BFW97_RS16430	COG3153	acetyltransferase
BFW97_RS16440	COG0625	glutathione transferase activity
BFW97_RS16445	COG0259	pyridoxamine-phosphate oxidase activity
BFW97_RS16460	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW97_RS16460	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW97_RS16465	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BFW97_RS16480	COG4235	cytochrome complex assembly
BFW97_RS16480	COG3088	subunit of a heme lyase
BFW97_RS16485	COG4235	cytochrome complex assembly
BFW97_RS16485	COG3088	subunit of a heme lyase
BFW97_RS16490	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BFW97_RS16495	COG1138	Cytochrome C-type biogenesis protein
BFW97_RS16500	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BFW97_RS16505	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW97_RS16510	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW97_RS16515	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BFW97_RS16530	COG0835	chemotaxis
BFW97_RS16540	COG1192	Involved in chromosome partitioning
BFW97_RS16545	COG1360	Flagellar Motor Protein
BFW97_RS16550	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BFW97_RS16555	COG2201	protein-glutamate methylesterase activity
BFW97_RS16560	COG2198	Histidine kinase
BFW97_RS16560	COG0784	Response regulator, receiver
BFW97_RS16560	COG0643	Histidine kinase
BFW97_RS16565	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BFW97_RS16590	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BFW97_RS16600	COG1684	flagellar biosynthetic protein fliR
BFW97_RS16655	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BFW97_RS16665	COG1677	Flagellar hook-basal body complex protein FliE
BFW97_RS16680	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BFW97_RS16700	COG2994	toxin metabolic process
BFW97_RS16710	COG2274	protein secretion by the type I secretion system
BFW97_RS16720	COG2274	protein secretion by the type I secretion system
BFW97_RS16740	COG1737	Transcriptional regulator
BFW97_RS16745	COG0469	pyruvate kinase activity
BFW97_RS16755	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_RS16760	COG1960	acyl-CoA dehydrogenase activity
BFW97_RS16770	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BFW97_RS16780	COG0243	molybdopterin cofactor binding
BFW97_RS16785	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BFW97_RS16790	COG0583	DNA-binding transcription factor activity
BFW97_RS16825	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_RS16825	COG1454	alcohol dehydrogenase
BFW97_RS16835	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_RS16835	COG1454	alcohol dehydrogenase
BFW97_RS16840	COG1882	Formate acetyltransferase
BFW97_RS16845	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_RS16855	COG4869	propanediol catabolic process
BFW97_RS16900	COG4409	exo-alpha-(2->6)-sialidase activity
BFW97_RS16910	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BFW97_RS16920	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BFW97_RS16925	COG1737	Transcriptional regulator
BFW97_RS16930	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BFW97_RS16935	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BFW97_RS16940	COG1349	DNA-binding transcription factor activity
BFW97_RS16945	COG0738	Major facilitator superfamily
BFW97_RS16955	COG1070	Carbohydrate kinase
BFW97_RS16975	COG4172	Belongs to the ABC transporter superfamily
BFW97_RS16980	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BFW97_RS16990	COG0747	negative chemotaxis
BFW97_RS17010	COG1376	ErfK ybiS ycfS ynhG family protein
BFW97_RS17010	COG1388	LysM domain
BFW97_RS17025	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BFW97_RS17030	COG0791	NLP P60 protein
BFW97_RS17035	COG2091	lysine biosynthetic process via aminoadipic acid
BFW97_RS17040	COG3118	belongs to the thioredoxin family
BFW97_RS17050	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BFW97_RS17055	COG0788	formyltetrahydrofolate deformylase activity
BFW97_RS17065	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW97_RS17085	COG0366	Alpha amylase catalytic
BFW97_RS17090	COG0739	heme binding
BFW97_RS17090	COG1196	nuclear chromosome segregation
BFW97_RS17090	COG0741	lytic transglycosylase activity
BFW97_RS17095	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BFW97_RS17100	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BFW97_RS17110	COG0673	inositol 2-dehydrogenase activity
BFW97_RS17130	COG1032	radical SAM domain protein
BFW97_RS17140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BFW97_RS17145	COG1566	PFAM secretion protein HlyD family protein
BFW97_RS17155	COG1752	Esterase of the alpha-beta hydrolase superfamily
BFW97_RS17160	COG0733	neurotransmitter:sodium symporter activity
BFW97_RS17190	COG0281	malic enzyme
BFW97_RS17200	COG0534	Mate efflux family protein
BFW97_RS17215	COG2233	PERMEase
BFW97_RS17220	COG0095	Lipoate-protein ligase
BFW97_RS17225	COG1115	amino acid carrier protein
BFW97_RS17230	COG0019	diaminopimelate decarboxylase activity
BFW97_RS17240	COG0678	peroxiredoxin activity
BFW97_RS17250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BFW97_RS17270	COG1131	(ABC) transporter
BFW97_RS17275	COG0545	Peptidyl-prolyl cis-trans isomerase
BFW97_RS17280	COG3142	Participates in the control of copper homeostasis
BFW97_RS17305	COG5002	protein histidine kinase activity
BFW97_RS17310	COG0745	RESPONSE REGULATOR receiver
BFW97_RS17315	COG0346	lactoylglutathione lyase activity
BFW97_RS17320	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BFW97_RS17325	COG1960	acyl-CoA dehydrogenase activity
BFW97_RS17330	COG3284	Transcriptional regulator
BFW97_RS17345	COG0697	spore germination
BFW97_RS17350	COG4565	transcriptional regulatory protein
BFW97_RS17355	COG3290	protein histidine kinase activity
BFW97_RS17360	COG0281	malic enzyme
BFW97_RS17375	COG1846	Transcriptional regulator
BFW97_RS17380	COG1566	PFAM secretion protein HlyD family protein
BFW97_RS17410	COG0602	queuosine metabolic process
BFW97_RS17415	COG1328	CTP reductase activity
BFW97_RS17425	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BFW97_RS17430	COG3115	cell septum assembly
BFW97_RS17435	COG1196	nuclear chromosome segregation
BFW97_RS17445	COG2860	membrane
BFW97_RS17455	COG3108	Peptidase M15
BFW97_RS17460	COG2989	Protein conserved in bacteria
BFW97_RS17475	COG0463	Glycosyl transferase, family 2
BFW97_RS17490	COG0366	Alpha amylase catalytic
BFW97_RS17525	COG3706	GGDEF domain
BFW97_RS17535	COG3590	peptidase
BFW97_RS17545	COG0488	(ABC) transporter
BFW97_RS17555	COG0531	amino acid
BFW97_RS17570	COG0814	amino acid
BFW97_RS17585	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BFW97_RS17590	COG1982	Orn Lys Arg decarboxylase major
BFW97_RS17595	COG0531	amino acid
BFW97_RS17600	COG3710	Transcriptional regulator
BFW97_RS17605	COG0825	malonyl-CoA metabolic process
BFW97_RS17615	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BFW97_RS17620	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_RS17625	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_RS17630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BFW97_RS17635	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BFW97_RS17650	COG0750	zinc metalloprotease
BFW97_RS17655	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BFW97_RS17660	COG0575	Belongs to the CDS family
BFW97_RS17665	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BFW97_RS17670	COG0233	cytoplasmic translational termination
BFW97_RS17675	COG0528	UMP kinase activity
BFW97_RS17680	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BFW97_RS17685	COG0052	Belongs to the universal ribosomal protein uS2 family
BFW97_RS17690	COG0024	Methionine aminopeptidase
BFW97_RS17695	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BFW97_RS17700	COG2171	N-acyltransferase activity
BFW97_RS17710	COG1263	PTS System
BFW97_RS17710	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS17720	COG4580	involved in the transport of maltose and maltodextrins
BFW97_RS17730	COG0564	pseudouridine synthase activity
BFW97_RS17735	COG3098	single-species biofilm formation
BFW97_RS17760	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BFW97_RS17770	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW97_RS17770	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BFW97_RS17785	COG1611	Belongs to the LOG family
BFW97_RS17790	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW97_RS17795	COG0473	3-isopropylmalate dehydrogenase activity
BFW97_RS17805	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BFW97_RS17810	COG2363	Small membrane protein
BFW97_RS17820	COG0583	DNA-binding transcription factor activity
BFW97_RS17825	COG0840	transmembrane signaling receptor activity
BFW97_RS17830	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BFW97_RS17845	COG1477	protein flavinylation
BFW97_RS17850	COG2871	sodium ion transport
BFW97_RS17855	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_RS17860	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_RS17865	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_RS17870	COG1805	sodium ion transport
BFW97_RS17875	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BFW97_RS17880	COG0271	Belongs to the BolA IbaG family
BFW97_RS17885	COG2813	Specifically methylates the guanine in position
BFW97_RS17895	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BFW97_RS17905	COG2211	Major facilitator Superfamily
BFW97_RS17910	COG3248	Nucleoside-binding outer membrane protein
BFW97_RS17915	COG1666	GTP binding
BFW97_RS17920	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BFW97_RS17925	COG0693	protein deglycase activity
BFW97_RS17975	COG2771	luxR family
BFW97_RS17995	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BFW97_RS17995	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW97_RS18000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BFW97_RS18010	COG1151	hydroxylamine reductase activity
BFW97_RS18015	COG0783	Belongs to the Dps family
BFW97_RS18040	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BFW97_RS18055	COG4221	oxidoreductase activity
BFW97_RS18065	COG0415	Belongs to the DNA photolyase family
BFW97_RS18070	COG0789	Transcriptional regulator
BFW97_RS18075	COG3272	Protein of unknown function (DUF1722)
BFW97_RS18105	COG0077	Prephenate dehydratase
BFW97_RS18105	COG1605	Chorismate mutase
BFW97_RS18135	COG5377	YqaJ viral recombinase family
BFW97_RS18180	COG2003	Belongs to the UPF0758 family
BFW97_RS18190	COG0602	queuosine metabolic process
BFW97_RS18195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BFW97_RS18210	COG0720	synthase
BFW97_RS18245	COG0514	ATP-dependent DNA helicase (RecQ)
BFW97_RS18250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFW97_RS18275	COG4771	TonB-dependent receptor
BFW97_RS18295	COG1116	anion transmembrane transporter activity
BFW97_RS18320	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_RS18325	COG1120	ATPase activity
BFW97_RS18335	COG2226	methyltransferase
BFW97_RS18365	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_RS18370	COG1120	ATPase activity
BFW97_RS18380	COG2226	methyltransferase
BFW97_RS18425	COG2133	pyrroloquinoline quinone binding
BFW97_RS18435	COG0840	transmembrane signaling receptor activity
BFW97_RS18445	COG0300	oxidoreductase activity
BFW97_RS18470	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BFW97_RS18485	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BFW97_RS18500	COG0826	peptidase U32
BFW97_RS18505	COG1280	lysine exporter protein (LysE YggA)
BFW97_RS18515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BFW97_RS18520	COG0840	transmembrane signaling receptor activity
BFW97_RS18535	COG0643	Histidine kinase
BFW97_RS18535	COG2198	Histidine kinase
BFW97_RS18545	COG0835	chemotaxis
BFW97_RS18550	COG0840	transmembrane signaling receptor activity
BFW97_RS18560	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BFW97_RS18565	COG2201	protein-glutamate methylesterase activity
BFW97_RS18570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BFW97_RS18600	COG2199	diguanylate cyclase activity
BFW97_RS18600	COG2203	Gaf domain
BFW97_RS18600	COG2200	EAL domain
BFW97_RS18605	COG0826	peptidase U32
BFW97_RS18610	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BFW97_RS18625	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BFW97_RS18635	COG0305	Participates in initiation and elongation during chromosome replication
BFW97_RS18650	COG2200	EAL domain
BFW97_RS18655	COG0737	Belongs to the 5'-nucleotidase family
BFW97_RS18675	COG2204	response regulator
BFW97_RS18680	COG0545	Peptidyl-prolyl cis-trans isomerase
BFW97_RS18695	COG1047	Peptidyl-prolyl cis-trans
BFW97_RS18700	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BFW97_RS18710	COG0835	chemotaxis
BFW97_RS18710	COG0784	Response regulator, receiver
BFW97_RS18715	COG0429	hydrolase of the alpha beta-hydrolase fold
BFW97_RS18720	COG4251	negative regulation of phosphorylation
BFW97_RS18720	COG3706	GGDEF domain
BFW97_RS18720	COG2203	Gaf domain
BFW97_RS18720	COG5001	Diguanylate cyclase
BFW97_RS18725	COG3089	Belongs to the UPF0270 family
BFW97_RS18735	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BFW97_RS18740	COG0463	Glycosyl transferase, family 2
BFW97_RS18745	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BFW97_RS18745	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFW97_RS18750	COG0726	polysaccharide deacetylase
BFW97_RS18755	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BFW97_RS18760	COG2076	Multidrug Resistance protein
BFW97_RS18765	COG2076	Multidrug Resistance protein
BFW97_RS18770	COG3954	Phosphoribulokinase
BFW97_RS18785	COG1765	OsmC-like protein
BFW97_RS18795	COG2226	methyltransferase
BFW97_RS18800	COG3397	chitin binding
BFW97_RS18815	COG2202	Pas domain
BFW97_RS18815	COG2205	protein histidine kinase activity
BFW97_RS18825	COG3655	Transcriptional regulator
BFW97_RS18830	COG2814	Major facilitator Superfamily
BFW97_RS18840	COG4771	TonB-dependent receptor
BFW97_RS18860	COG0748	coenzyme F420 binding
BFW97_RS18865	COG3721	Heme iron utilization protein
BFW97_RS18875	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BFW97_RS18900	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BFW97_RS18905	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_RS18910	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BFW97_RS18930	COG0741	lytic transglycosylase activity
BFW97_RS18935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BFW97_RS19030	COG0616	signal peptide processing
BFW97_RS19045	COG1802	Transcriptional regulator
BFW97_RS19045	COG4626	Terminase
BFW97_RS19095	COG0464	growth
BFW97_RS19105	COG4416	COG NOG18757 non supervised orthologous group
BFW97_RS19240	COG0582	viral genome integration into host DNA
BFW97_RS19245	COG0488	(ABC) transporter
BFW97_RS19255	COG2252	PERMEase
BFW97_RS19260	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BFW97_RS19265	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BFW97_RS19275	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BFW97_RS19285	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BFW97_RS19290	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BFW97_RS19295	COG2967	ApaG domain
BFW97_RS19300	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BFW97_RS19310	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BFW97_RS19315	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BFW97_RS19330	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_RS19335	COG3314	Sporulation integral membrane protein YlbJ
BFW97_RS19340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BFW97_RS19345	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BFW97_RS19350	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BFW97_RS19355	COG0142	geranyltranstransferase activity
BFW97_RS19360	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BFW97_RS19365	COG0330	HflC and HflK could
BFW97_RS19370	COG0330	HflC and HflK could
BFW97_RS19375	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BFW97_RS19380	COG1923	regulation of RNA biosynthetic process
BFW97_RS19385	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BFW97_RS19390	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BFW97_RS19400	COG0802	atpase or kinase
BFW97_RS19405	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BFW97_RS19405	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BFW97_RS19430	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BFW97_RS19435	COG2011	ABC-type metal ion transport system permease component
BFW97_RS19440	COG1464	Belongs to the NlpA lipoprotein family
BFW97_RS19450	COG0840	transmembrane signaling receptor activity
BFW97_RS19475	COG0784	Response regulator, receiver
BFW97_RS19475	COG2198	Histidine kinase
BFW97_RS19475	COG5002	protein histidine kinase activity
BFW97_RS19495	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
BFW97_RS19510	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BFW97_RS19515	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BFW97_RS19525	COG2716	regulation of RNA biosynthetic process
BFW97_RS19530	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BFW97_RS19535	COG3013	Belongs to the UPF0304 family
BFW97_RS19545	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BFW97_RS19550	COG0280	phosphate acetyltransferase
BFW97_RS19550	COG0857	belongs to the CobB CobQ family
BFW97_RS19560	COG0028	Belongs to the TPP enzyme family
BFW97_RS19575	COG0671	phosphoesterase, PA-phosphatase related
BFW97_RS19585	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BFW97_RS19590	COG0473	3-isopropylmalate dehydrogenase activity
BFW97_RS19595	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BFW97_RS19600	COG0066	3-isopropylmalate dehydratase activity
BFW97_RS19620	COG1178	ABC-type Fe3 transport system permease component
BFW97_RS19625	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BFW97_RS19630	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BFW97_RS19640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BFW97_RS19670	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BFW97_RS19675	COG0564	pseudouridine synthase activity
BFW97_RS19690	COG5001	Diguanylate cyclase
BFW97_RS19690	COG3300	MHYT domain
BFW97_RS19700	COG0459	protein refolding
BFW97_RS19705	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BFW97_RS19710	COG0534	Mate efflux family protein
BFW97_RS19715	COG3030	protein affecting phage T7 exclusion by the F plasmid
BFW97_RS19720	COG1027	Aspartate ammonia-lyase
BFW97_RS19725	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BFW97_RS19735	COG0477	Major facilitator Superfamily
BFW97_RS19755	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BFW97_RS19765	COG0673	inositol 2-dehydrogenase activity
BFW97_RS19775	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BFW97_RS19780	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW97_RS19785	COG3036	rescue of stalled ribosome
BFW97_RS19790	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BFW97_RS19800	COG0138	bifunctional purine biosynthesis protein purh
BFW97_RS19805	COG0151	Belongs to the GarS family
BFW97_RS19835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BFW97_RS19840	COG0358	DNA primase activity
BFW97_RS19845	COG1610	YqeY-like protein
BFW97_RS19850	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BFW97_RS19855	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BFW97_RS19870	COG1238	metal cluster binding
BFW97_RS19875	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BFW97_RS19880	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BFW97_RS19885	COG0585	pseudouridine synthase activity
BFW97_RS19895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BFW97_RS19900	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BFW97_RS19905	COG0148	phosphopyruvate hydratase activity
BFW97_RS19910	COG0504	CTP synthase activity
BFW97_RS19915	COG3956	TIGRFAM MazG family protein
BFW97_RS19920	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BFW97_RS19925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BFW97_RS19935	COG4807	Protein conserved in bacteria
BFW97_RS19940	COG3023	N-Acetylmuramoyl-L-alanine amidase
BFW97_RS19945	COG1349	DNA-binding transcription factor activity
BFW97_RS19955	COG2222	sugar isomerase
BFW97_RS19960	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS19970	COG3716	PTS system mannose fructose sorbose family IID component
BFW97_RS19975	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS19980	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BFW97_RS19995	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BFW97_RS20000	COG1381	Involved in DNA repair and RecF pathway recombination
BFW97_RS20010	COG0571	ribonuclease III activity
BFW97_RS20015	COG0681	Belongs to the peptidase S26 family
BFW97_RS20020	COG0481	GTPase activity
BFW97_RS20035	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BFW97_RS20040	COG1595	DNA-templated transcription, initiation
BFW97_RS20045	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BFW97_RS20055	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BFW97_RS20060	COG0354	folic acid binding
BFW97_RS20095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BFW97_RS20100	COG0191	fructose-bisphosphate aldolase activity
BFW97_RS20105	COG0126	phosphoglycerate kinase activity
BFW97_RS20110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BFW97_RS20115	COG1940	carbohydrate kinase activity
BFW97_RS20120	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BFW97_RS20135	COG4991	sh3 domain protein
BFW97_RS20140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BFW97_RS20155	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BFW97_RS20175	COG1505	serine-type exopeptidase activity
BFW97_RS20180	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BFW97_RS20185	COG0765	amino acid transport
BFW97_RS20190	COG0765	amino acid transport
BFW97_RS20195	COG1126	abc transporter atp-binding protein
BFW97_RS20200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS20205	COG1136	(ABC) transporter
BFW97_RS20205	COG0577	efflux transmembrane transporter activity
BFW97_RS20210	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BFW97_RS20215	COG0745	RESPONSE REGULATOR receiver
BFW97_RS20220	COG2205	protein histidine kinase activity
BFW97_RS20260	COG2070	2-Nitropropane dioxygenase
BFW97_RS20285	COG1858	cytochrome C peroxidase
BFW97_RS20290	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BFW97_RS20310	COG0513	Belongs to the DEAD box helicase family
BFW97_RS20325	COG0154	amidase activity
BFW97_RS20330	COG2957	Belongs to the agmatine deiminase family
BFW97_RS20345	COG1902	pentaerythritol trinitrate reductase activity
BFW97_RS20390	COG0714	Associated with various cellular activities
BFW97_RS20400	COG0456	acetyltransferase
BFW97_RS20410	COG1022	Amp-dependent synthetase and ligase
BFW97_RS20420	COG2918	glutathione biosynthetic process
BFW97_RS20425	COG0612	Peptidase, M16
BFW97_RS20430	COG1238	metal cluster binding
BFW97_RS20455	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW97_RS20460	COG0359	binds to the 23S rRNA
BFW97_RS20465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BFW97_RS20470	COG0360	Binds together with S18 to 16S ribosomal RNA
BFW97_RS20475	COG1914	H( )-stimulated, divalent metal cation uptake system
BFW97_RS20495	COG2153	protein acetylation
BFW97_RS20505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BFW97_RS20510	COG0557	exoribonuclease II activity
BFW97_RS20515	COG3706	GGDEF domain
BFW97_RS20520	COG1854	S-ribosylhomocysteine lyase activity
BFW97_RS20535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BFW97_RS20535	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFW97_RS20590	COG4970	Tfp pilus assembly protein FimT
BFW97_RS20595	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BFW97_RS20600	COG1047	Peptidyl-prolyl cis-trans
BFW97_RS20605	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BFW97_RS20610	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BFW97_RS20615	COG0196	riboflavin kinase activity
BFW97_RS20620	COG0728	peptidoglycan biosynthetic process
BFW97_RS20625	COG0268	Binds directly to 16S ribosomal RNA
BFW97_RS20630	COG0640	Transcriptional regulator
BFW97_RS20635	COG0583	DNA-binding transcription factor activity
BFW97_RS20645	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BFW97_RS20650	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BFW97_RS20655	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BFW97_RS20665	COG1051	belongs to the nudix hydrolase family
BFW97_RS20670	COG3066	DNA modification
BFW97_RS20680	COG0335	large ribosomal subunit rRNA binding
BFW97_RS20685	COG0336	Belongs to the RNA methyltransferase TrmD family
BFW97_RS20690	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BFW97_RS20695	COG0228	four-way junction DNA binding
BFW97_RS20700	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BFW97_RS20705	COG4137	Cytochrome C assembly protein
BFW97_RS20710	COG4536	flavin adenine dinucleotide binding
BFW97_RS20720	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BFW97_RS20720	COG1017	nitric oxide dioxygenase activity
BFW97_RS20725	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BFW97_RS20730	COG0039	L-malate dehydrogenase activity
BFW97_RS20735	COG4160	amino acid transport
BFW97_RS20740	COG4215	(ABC) transporter
BFW97_RS20745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BFW97_RS20750	COG1126	abc transporter atp-binding protein
BFW97_RS20755	COG1438	arginine binding
BFW97_RS20760	COG2837	iron assimilation
BFW97_RS20765	COG3842	ATPase activity
BFW97_RS20775	COG1840	ABC-type Fe3 transport system, periplasmic component
BFW97_RS20780	COG0347	Belongs to the P(II) protein family
BFW97_RS20795	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_RS20800	COG0583	DNA-binding transcription factor activity
BFW97_RS20815	COG1929	Belongs to the glycerate kinase type-1 family
BFW97_RS20820	COG2610	gluconate transmembrane transporter activity
BFW97_RS20825	COG3835	regulator
BFW97_RS20830	COG3112	Uncharacterised protein family (UPF0231)
BFW97_RS20845	COG0840	transmembrane signaling receptor activity
BFW97_RS20865	COG0513	Belongs to the DEAD box helicase family
BFW97_RS20905	COG1448	Aminotransferase
BFW97_RS20920	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BFW97_RS20925	COG1328	CTP reductase activity
BFW97_RS20945	COG4946	Tricorn protease homolog
BFW97_RS20945	COG0793	Belongs to the peptidase S41A family
BFW97_RS20980	COG0840	transmembrane signaling receptor activity
BFW97_RS20985	COG3397	chitin binding
BFW97_RS20990	COG0583	DNA-binding transcription factor activity
BFW97_RS20995	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BFW97_RS21000	COG4208	sulfate ABC transporter
BFW97_RS21005	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BFW97_RS21015	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BFW97_RS21020	COG3174	membrane
BFW97_RS21025	COG0110	maltose O-acetyltransferase activity
BFW97_RS21050	COG0165	Argininosuccinate lyase
BFW97_RS21055	COG0137	argininosuccinate synthase activity
BFW97_RS21065	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BFW97_RS21070	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BFW97_RS21080	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BFW97_RS21090	COG0460	homoserine dehydrogenase
BFW97_RS21090	COG0527	aspartate kinase activity
BFW97_RS21095	COG0626	cystathionine gamma-synthase activity
BFW97_RS21105	COG2207	Transcriptional regulator
BFW97_RS21105	COG3708	Transcriptional regulator
BFW97_RS21110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_RS21115	COG0814	amino acid
BFW97_RS21120	COG1218	3'(2'),5'-bisphosphate nucleotidase
BFW97_RS21125	COG0494	nUDIX hydrolase
BFW97_RS21130	COG1011	Hydrolase
BFW97_RS21135	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BFW97_RS21150	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BFW97_RS21160	COG3156	type II secretion system protein K
BFW97_RS21165	COG4795	General secretion pathway protein
BFW97_RS21170	COG2165	general secretion pathway protein
BFW97_RS21185	COG2165	general secretion pathway protein
BFW97_RS21190	COG1459	type II secretion system
BFW97_RS21195	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW97_RS21205	COG3031	protein transport across the cell outer membrane
BFW97_RS21215	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BFW97_RS21220	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BFW97_RS21240	COG0456	acetyltransferase
BFW97_RS21245	COG3133	Outer membrane lipoprotein
BFW97_RS21260	COG2771	luxR family
BFW97_RS21265	COG3916	Acyl-homoserine-lactone synthase
BFW97_RS21275	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BFW97_RS21280	COG1309	transcriptional regulator
BFW97_RS21290	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BFW97_RS21290	COG2213	PTS system mannitol-specific
BFW97_RS21295	COG0246	Mannitol dehydrogenase
BFW97_RS21300	COG3722	fumarate hydratase activity
BFW97_RS21305	COG3263	regulation of cellular component size
BFW97_RS21330	COG1671	Belongs to the UPF0178 family
BFW97_RS21345	COG1988	membrane-bound metal-dependent
BFW97_RS21350	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BFW97_RS21355	COG0513	Belongs to the DEAD box helicase family
BFW97_RS21380	COG1575	Belongs to the MenA family. Type 1 subfamily
BFW97_RS21385	COG1169	isochorismate synthase
BFW97_RS21390	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BFW97_RS21395	COG0596	Alpha beta hydrolase
BFW97_RS21400	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BFW97_RS21405	COG1441	menaquinone biosynthetic process
BFW97_RS21410	COG0318	PFAM AMP-dependent synthetase and ligase
BFW97_RS21425	COG3539	Fimbrial protein
BFW97_RS21430	COG3121	Chaperone
BFW97_RS21435	COG3188	usher protein
BFW97_RS21445	COG3539	Fimbrial protein
BFW97_RS21455	COG3291	Pkd domain containing protein
BFW97_RS21460	COG2949	membrane
BFW97_RS21465	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BFW97_RS21480	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BFW97_RS21485	COG5380	lipid catabolic process
BFW97_RS21500	COG4533	DNA binding
BFW97_RS21510	COG2873	o-acetylhomoserine
BFW97_RS21520	COG1979	alcohol dehydrogenase
BFW97_RS21540	COG4221	oxidoreductase activity
BFW97_RS21560	COG1285	pathogenesis
BFW97_RS21580	COG1368	sulfuric ester hydrolase activity
BFW97_RS21585	COG1522	sequence-specific DNA binding
BFW97_RS21595	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BFW97_RS21600	COG1418	mRNA catabolic process
BFW97_RS21605	COG1058	Belongs to the CinA family
BFW97_RS21605	COG1546	Belongs to the CinA family
BFW97_RS21615	COG0842	Transport permease protein
BFW97_RS21615	COG1129	ABC transporter
BFW97_RS21630	COG0561	phosphatase activity
BFW97_RS21635	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BFW97_RS21655	COG1011	Hydrolase
BFW97_RS21670	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BFW97_RS21675	COG0019	diaminopimelate decarboxylase activity
BFW97_RS21685	COG1965	Belongs to the frataxin family
BFW97_RS21690	COG0400	carboxylic ester hydrolase activity
BFW97_RS21695	COG3072	Adenylate cyclase
BFW97_RS21700	COG0181	hydroxymethylbilane synthase activity
BFW97_RS21710	COG2959	enzyme of heme biosynthesis
BFW97_RS21725	COG1494	fructose-1,6-bisphosphatase
BFW97_RS21765	COG1733	regulation of RNA biosynthetic process
BFW97_RS21785	COG3932	Exopolysaccharide synthesis, ExoD
BFW97_RS21790	COG0814	amino acid
BFW97_RS21810	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BFW97_RS21820	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BFW97_RS21825	COG2022	thiamine diphosphate biosynthetic process
BFW97_RS21835	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BFW97_RS21840	COG0352	thiamine-phosphate diphosphorylase activity
BFW97_RS21845	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BFW97_RS21860	COG0745	RESPONSE REGULATOR receiver
BFW97_RS21865	COG0642	Histidine kinase
BFW97_RS21875	COG0189	ligase activity
BFW97_RS21920	COG3171	Protein conserved in bacteria
BFW97_RS21935	COG3188	usher protein
BFW97_RS21985	COG1639	'signal transduction protein
BFW97_RS21995	COG2321	neutral zinc metallopeptidase
BFW97_RS22000	COG3700	Belongs to the class B bacterial acid phosphatase family
BFW97_RS22020	COG1366	Belongs to the anti-sigma-factor antagonist family
BFW97_RS22025	COG2172	sigma factor antagonist activity
BFW97_RS22030	COG2205	protein histidine kinase activity
BFW97_RS22030	COG5002	protein histidine kinase activity
BFW97_RS22030	COG0784	Response regulator, receiver
BFW97_RS22035	COG3437	response regulator, receiver
BFW97_RS22045	COG0477	Major facilitator Superfamily
BFW97_RS22060	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BFW97_RS22065	COG1263	PTS System
BFW97_RS22065	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BFW97_RS22085	COG0312	modulator of DNA gyrase
BFW97_RS22090	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BFW97_RS22100	COG3164	Protein of unknown function
BFW97_RS22105	COG1530	ribonuclease E activity
BFW97_RS22110	COG0424	maF-like protein
BFW97_RS22115	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BFW97_RS22120	COG1792	Involved in formation and maintenance of cell shape
BFW97_RS22125	COG1077	Cell shape determining protein MreB Mrl
BFW97_RS22150	COG4968	Prepilin-type N-terminal cleavage methylation domain
BFW97_RS22155	COG4969	Belongs to the N-Me-Phe pilin family
BFW97_RS22160	COG2165	general secretion pathway protein
BFW97_RS22170	COG1459	type II secretion system
BFW97_RS22175	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BFW97_RS22185	COG2842	Transposition protein
BFW97_RS22220	COG2200	EAL domain
BFW97_RS22220	COG2199	diguanylate cyclase activity
BFW97_RS22225	COG2200	EAL domain
BFW97_RS22230	COG0387	Pfam Sodium calcium exchanger
BFW97_RS22235	COG2986	histidine ammonia-lyase
BFW97_RS22240	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BFW97_RS22245	COG0010	Belongs to the arginase family
BFW97_RS22250	COG1228	amidohydrolase
BFW97_RS22255	COG2188	Transcriptional regulator
BFW97_RS22260	COG0288	reversible hydration of carbon dioxide
BFW97_RS22270	COG2177	Part of the ABC transporter FtsEX involved in
BFW97_RS22275	COG2884	Cell division ATP-binding protein ftsE
BFW97_RS22280	COG0552	protein localization to endoplasmic reticulum
BFW97_RS22285	COG0742	ribosomal rna small subunit methyltransferase
BFW97_RS22310	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW97_RS22315	COG0741	lytic transglycosylase activity
BFW97_RS22325	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFW97_RS22335	COG2095	MarC family integral membrane protein
BFW97_RS22345	COG1301	dicarboxylic acid transport
BFW97_RS22370	COG3714	YhhN family
BFW97_RS22395	COG1770	oligopeptidase
BFW97_RS22410	COG4221	oxidoreductase activity
BFW97_RS22415	COG0583	DNA-binding transcription factor activity
BFW97_RS22420	COG2249	NAD(P)H dehydrogenase (quinone) activity
BFW97_RS22470	COG0203	ribosomal protein L17
BFW97_RS22475	COG0202	RNA polymerase activity
BFW97_RS22480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BFW97_RS22485	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BFW97_RS22490	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BFW97_RS22495	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BFW97_RS22500	COG0201	protein transport
BFW97_RS22505	COG0200	Binds to the 23S rRNA
BFW97_RS22510	COG1841	ribosomal large subunit assembly
BFW97_RS22515	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BFW97_RS22520	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BFW97_RS22525	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BFW97_RS22530	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BFW97_RS22535	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BFW97_RS22540	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BFW97_RS22545	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BFW97_RS22550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BFW97_RS22555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BFW97_RS22560	COG0255	Belongs to the universal ribosomal protein uL29 family
BFW97_RS22565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BFW97_RS22570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BFW97_RS22575	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BFW97_RS22580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BFW97_RS22585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BFW97_RS22590	COG0089	rRNA binding
BFW97_RS22595	COG0088	Forms part of the polypeptide exit tunnel
BFW97_RS22600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BFW97_RS22605	COG0051	transcription antitermination factor activity, RNA binding
BFW97_RS22625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BFW97_RS22630	COG2183	response to ionizing radiation
BFW97_RS22650	COG0596	Alpha beta hydrolase
BFW97_RS22655	COG1040	competence protein
BFW97_RS22660	COG0316	Belongs to the HesB IscA family
BFW97_RS22660	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BFW97_RS22665	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BFW97_RS22670	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BFW97_RS22675	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW97_RS22680	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BFW97_RS22685	COG4942	peptidase
BFW97_RS22695	COG1609	Transcriptional regulator
BFW97_RS22700	COG0800	Aldolase
BFW97_RS22705	COG0129	dihydroxy-acid dehydratase activity
BFW97_RS22710	COG3265	gluconokinase activity
BFW97_RS22715	COG2610	gluconate transmembrane transporter activity
BFW97_RS22720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BFW97_RS22725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BFW97_RS22735	COG0456	acetyltransferase
BFW97_RS22745	COG1490	D-aminoacyl-tRNA deacylase activity
BFW97_RS22750	COG1295	ribonuclease BN
BFW97_RS22755	COG1217	gtp-binding protein TYPA
BFW97_RS22760	COG0174	glutamine synthetase
BFW97_RS22770	COG3852	Histidine kinase
BFW97_RS22775	COG2204	response regulator
BFW97_RS22780	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BFW97_RS22785	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BFW97_RS22795	COG3078	GTPase activator activity
BFW97_RS22810	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BFW97_RS22820	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BFW97_RS22825	COG0408	coproporphyrinogen oxidase activity
BFW97_RS22830	COG0009	L-threonylcarbamoyladenylate synthase
BFW97_RS22840	COG0551	DNA topoisomerase type I activity
BFW97_RS22845	COG2922	Belongs to the Smg family
BFW97_RS22850	COG0758	DNA mediated transformation
BFW97_RS22860	COG0242	peptide deformylase activity
BFW97_RS22865	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BFW97_RS22870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BFW97_RS22870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BFW97_RS22875	COG0569	domain protein
BFW97_RS22880	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW97_RS22885	COG1322	Protein conserved in bacteria
BFW97_RS22905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BFW97_RS22910	COG0686	Belongs to the AlaDH PNT family
BFW97_RS22915	COG0519	Catalyzes the synthesis of GMP from XMP
BFW97_RS22915	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BFW97_RS22925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BFW97_RS22930	COG1396	sequence-specific DNA binding
BFW97_RS22935	COG1012	belongs to the aldehyde dehydrogenase family
BFW97_RS22945	COG2962	Rard protein
BFW97_RS22955	COG1280	lysine exporter protein (LysE YggA)
BFW97_RS22965	COG2391	methyltransferase activity
BFW97_RS22970	COG1280	lysine exporter protein (LysE YggA)
BFW97_RS23015	COG0583	DNA-binding transcription factor activity
BFW97_RS23020	COG1943	Transposase
BFW97_RS23025	COG0210	DNA helicase
BFW97_RS23030	COG1744	ABC transporter substrate-binding protein PnrA-like
BFW97_RS23035	COG3845	ABC transporter
BFW97_RS23040	COG4603	Belongs to the binding-protein-dependent transport system permease family
BFW97_RS23045	COG1079	Belongs to the binding-protein-dependent transport system permease family
BFW97_RS23050	COG0583	DNA-binding transcription factor activity
BFW97_RS23070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BFW97_RS23075	COG0385	Bile acid
BFW97_RS23080	COG0531	amino acid
BFW97_RS23085	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BFW97_RS23090	COG0531	amino acid
BFW97_RS23095	COG2731	YhcH YjgK YiaL family protein
BFW97_RS23100	COG3250	beta-galactosidase activity
BFW97_RS23105	COG1609	Transcriptional regulator
BFW97_RS23145	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BFW97_RS23150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW97_RS23150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BFW97_RS23155	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BFW97_RS23160	COG3074	FtsZ-dependent cytokinesis
BFW97_RS23170	COG1045	serine acetyltransferase
BFW97_RS23180	COG0745	RESPONSE REGULATOR receiver
BFW97_RS23185	COG2205	protein histidine kinase activity
BFW97_RS23190	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BFW97_RS23195	COG0534	Mate efflux family protein
BFW97_RS23220	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BFW97_RS23225	COG2937	Belongs to the GPAT DAPAT family
BFW97_RS23230	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BFW97_RS23235	COG3161	chorismate lyase activity
BFW97_RS23240	COG1580	Controls the rotational direction of flagella during chemotaxis
BFW97_RS23260	COG0604	alcohol dehydrogenase
BFW97_RS23265	COG1609	Transcriptional regulator
BFW97_RS23285	COG1519	Transferase
BFW97_RS23290	COG0859	PFAM glycosyl transferase family 9
BFW97_RS23295	COG0463	Glycosyl transferase, family 2
BFW97_RS23300	COG0859	PFAM glycosyl transferase family 9
BFW97_RS23305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BFW97_RS23310	COG2990	Protein conserved in bacteria
BFW97_RS23315	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BFW97_RS23325	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BFW97_RS23330	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BFW97_RS23335	COG2003	Belongs to the UPF0758 family
BFW97_RS23340	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BFW97_RS23345	COG0756	dUTP diphosphatase activity
BFW97_RS23350	COG1309	transcriptional regulator
BFW97_RS23355	COG0668	transmembrane transport
BFW97_RS23365	COG0166	Belongs to the GPI family
BFW97_RS23370	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BFW97_RS23375	COG0583	DNA-binding transcription factor activity
BFW97_RS23415	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BFW97_RS23420	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BFW97_RS23425	COG1739	Uncharacterized protein family UPF0029
BFW97_RS23430	COG0006	proline dipeptidase activity
BFW97_RS23435	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BFW97_RS23440	COG1024	Enoyl-CoA hydratase
BFW97_RS23440	COG1250	3-hydroxyacyl-CoA dehydrogenase
BFW97_RS23445	COG0183	Belongs to the thiolase family
BFW97_RS23470	COG0425	Belongs to the sulfur carrier protein TusA family
BFW97_RS23475	COG0251	oxidation-reduction process
BFW97_RS23485	COG2885	chlorophyll binding
BFW97_RS23490	COG1335	isochorismatase
BFW97_RS23495	COG2818	Glycosylase
BFW97_RS23500	COG0752	glycyl-tRNA synthetase alpha subunit
BFW97_RS23505	COG0751	glycine-tRNA ligase activity
BFW97_RS23520	COG0529	Catalyzes the synthesis of activated sulfate
BFW97_RS23520	COG2046	Belongs to the sulfate adenylyltransferase family
BFW97_RS23540	COG0814	amino acid
BFW97_RS23545	COG0348	domain, Protein
BFW97_RS23555	COG0446	pyridine nucleotide-disulphide oxidoreductase
BFW97_RS23560	COG0426	domain, Protein
BFW97_RS23560	COG1773	rubredoxin
BFW97_RS23565	COG3604	Transcriptional regulator
BFW97_RS23570	COG2188	Transcriptional regulator
BFW97_RS23585	COG1609	Transcriptional regulator
BFW97_RS23625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BFW97_RS23650	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BFW97_RS23665	COG3118	belongs to the thioredoxin family
BFW97_RS23670	COG0513	Belongs to the DEAD box helicase family
BFW97_RS23675	COG0248	Ppx GppA phosphatase
BFW97_RS23690	COG0742	ribosomal rna small subunit methyltransferase
BFW97_RS23710	COG0084	hydrolase, TatD family'
BFW97_RS23715	COG0805	protein transport
BFW97_RS23720	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BFW97_RS23730	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BFW97_RS23735	COG3165	ubiquinone biosynthetic process from chorismate
BFW97_RS23745	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BFW97_RS23750	COG0402	S-adenosylhomocysteine deaminase activity
BFW97_RS23790	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BFW97_RS23795	COG0848	biopolymer transport protein
BFW97_RS23800	COG0811	peptide transport
BFW97_RS23805	COG0811	peptide transport
BFW97_RS23815	COG2771	luxR family
BFW97_RS23820	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BFW97_RS23825	COG1349	DNA-binding transcription factor activity
BFW97_RS23830	COG0745	RESPONSE REGULATOR receiver
BFW97_RS23835	COG2205	protein histidine kinase activity
BFW97_RS23845	COG4452	Inner membrane protein CreD
BFW97_RS23850	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BFW97_RS23855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BFW97_RS23860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BFW97_RS23865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BFW97_RS23870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BFW97_RS23875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BFW97_RS23880	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BFW97_RS23890	COG0356	it plays a direct role in the translocation of protons across the membrane
BFW97_RS23900	COG1475	DNA binding
BFW97_RS23905	COG1192	Involved in chromosome partitioning
BFW97_RS23910	COG0357	Ribosomal RNA small subunit methyltransferase G
BFW97_RS23915	COG0445	tRNA wobble uridine modification
BFW97_RS23920	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BFW97_RS23925	COG4774	siderophore transport
BFW97_RS23930	COG4615	Cyclic peptide transporter
BFW97_RS23935	COG1120	ATPase activity
BFW97_RS23950	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BFW97_RS23955	COG0706	membrane insertase activity
BFW97_RS23960	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BFW97_RS23965	COG0594	ribonuclease P activity
BFW97_RS23970	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BFW97_RS23975	COG1126	abc transporter atp-binding protein