locus-tag	class	description
C1A23_RS00080	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C1A23_RS00455	COG2176	DNA-directed DNA polymerase activity
C1A23_RS00455	COG5002	protein histidine kinase activity
C1A23_RS00560	COG3385	transposase activity
C1A23_RS00590	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1A23_RS00595	COG0625	glutathione transferase activity
C1A23_RS00620	COG1192	Involved in chromosome partitioning
C1A23_RS00645	COG1484	DNA-dependent DNA replication
C1A23_RS00650	COG4584	PFAM Integrase catalytic
C1A23_RS00660	COG2194	sulfuric ester hydrolase activity
C1A23_RS00750	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C1A23_RS00775	COG1660	Displays ATPase and GTPase activities
C1A23_RS00800	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1A23_RS00805	COG4804	nuclease activity
C1A23_RS00815	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1A23_RS00920	COG1357	PFAM Pentapeptide repeats (8 copies)
C1A23_RS00940	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C1A23_RS01015	COG4584	PFAM Integrase catalytic
C1A23_RS01020	COG1484	DNA-dependent DNA replication
C1A23_RS01060	COG5433	transposase activity
C1A23_RS01080	COG3300	MHYT domain
C1A23_RS01080	COG5001	Diguanylate cyclase
C1A23_RS01090	COG5433	transposase activity
C1A23_RS01105	COG3039	Transposase
C1A23_RS01115	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A23_RS01125	COG0166	Belongs to the GPI family
C1A23_RS01155	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS01165	COG1349	DNA-binding transcription factor activity
C1A23_RS01180	COG3385	transposase activity
C1A23_RS01195	COG2200	EAL domain
C1A23_RS01200	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1A23_RS01300	COG1484	DNA-dependent DNA replication
C1A23_RS01305	COG4584	PFAM Integrase catalytic
C1A23_RS01360	COG0675	Transposase, IS605 OrfB family
C1A23_RS01415	COG0675	Transposase, IS605 OrfB family
C1A23_RS01465	COG1192	Involved in chromosome partitioning
C1A23_RS01480	COG0675	Transposase, IS605 OrfB family
C1A23_RS01550	COG0675	Transposase, IS605 OrfB family
C1A23_RS01580	COG0305	Participates in initiation and elongation during chromosome replication
C1A23_RS01670	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1A23_RS01785	COG5002	protein histidine kinase activity
C1A23_RS01785	COG2176	DNA-directed DNA polymerase activity
C1A23_RS01810	COG0393	Putative heavy-metal-binding
C1A23_RS01820	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
C1A23_RS01845	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C1A23_RS01850	COG0592	DNA-directed DNA polymerase activity
C1A23_RS01855	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1A23_RS01880	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C1A23_RS01940	COG1484	DNA-dependent DNA replication
C1A23_RS01945	COG4584	PFAM Integrase catalytic
C1A23_RS01955	COG0071	Belongs to the small heat shock protein (HSP20) family
C1A23_RS01960	COG0071	Belongs to the small heat shock protein (HSP20) family
C1A23_RS01965	COG3977	Valine--pyruvate aminotransferase
C1A23_RS01980	COG2814	Major facilitator Superfamily
C1A23_RS01985	COG0745	RESPONSE REGULATOR receiver
C1A23_RS01990	COG2205	protein histidine kinase activity
C1A23_RS02015	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1A23_RS02020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS02020	COG4191	Histidine kinase
C1A23_RS02025	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS02030	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS02035	COG1309	transcriptional regulator
C1A23_RS02065	COG0561	phosphatase activity
C1A23_RS02070	COG2267	carboxylic ester hydrolase activity
C1A23_RS02075	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1A23_RS02080	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1A23_RS02085	COG1758	RNA polymerase activity
C1A23_RS02095	COG0859	PFAM glycosyl transferase family 9
C1A23_RS02100	COG3642	lipopolysaccharide core region biosynthetic process
C1A23_RS02140	COG0589	response to stress
C1A23_RS02145	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1A23_RS02155	COG1528	Iron-storage protein
C1A23_RS02160	COG2081	HI0933 family
C1A23_RS02165	COG2223	nitrite transmembrane transporter activity
C1A23_RS02185	COG3121	Chaperone
C1A23_RS02190	COG3188	usher protein
C1A23_RS02205	COG5433	transposase activity
C1A23_RS02210	COG2197	response regulator
C1A23_RS02215	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS02215	COG2205	protein histidine kinase activity
C1A23_RS02225	COG3275	phosphorelay sensor kinase activity
C1A23_RS02230	COG3279	Response regulator of the LytR AlgR family
C1A23_RS02235	COG2223	nitrite transmembrane transporter activity
C1A23_RS02240	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C1A23_RS02245	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C1A23_RS02260	COG0583	DNA-binding transcription factor activity
C1A23_RS02265	COG4206	TonB-dependent receptor
C1A23_RS02270	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C1A23_RS02305	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C1A23_RS02310	COG2166	iron-sulfur cluster assembly
C1A23_RS02315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1A23_RS02320	COG0210	DNA helicase
C1A23_RS02330	COG3245	cytochrome
C1A23_RS02335	COG1063	alcohol dehydrogenase
C1A23_RS02340	COG0156	8-amino-7-oxononanoate synthase activity
C1A23_RS02350	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1A23_RS02365	COG3306	glycosyltransferase involved in LPS biosynthesis
C1A23_RS02385	COG1561	YicC-like family, N-terminal region
C1A23_RS02390	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C1A23_RS02395	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C1A23_RS02405	COG0789	Transcriptional regulator
C1A23_RS02410	COG4251	negative regulation of phosphorylation
C1A23_RS02410	COG2203	Gaf domain
C1A23_RS02410	COG5001	Diguanylate cyclase
C1A23_RS02410	COG3706	GGDEF domain
C1A23_RS02415	COG3084	Protein conserved in bacteria
C1A23_RS02425	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C1A23_RS02430	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1A23_RS02440	COG1335	isochorismatase
C1A23_RS02450	COG1683	Conserved Protein
C1A23_RS02455	COG0204	Acyl-transferase
C1A23_RS02460	COG0204	Acyl-transferase
C1A23_RS02465	COG0606	chelatase, subunit chli
C1A23_RS02480	COG3978	acetolactate synthase activity
C1A23_RS02490	COG0129	dihydroxy-acid dehydratase activity
C1A23_RS02510	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C1A23_RS02515	COG0254	rRNA binding
C1A23_RS02520	COG0702	epimerase
C1A23_RS02525	COG0281	malic enzyme
C1A23_RS02535	COG2205	protein histidine kinase activity
C1A23_RS02540	COG0745	RESPONSE REGULATOR receiver
C1A23_RS02545	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1A23_RS02560	COG0366	Alpha amylase catalytic
C1A23_RS02575	COG0443	Heat shock 70 kDa protein
C1A23_RS02580	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1A23_RS02585	COG3045	CreA protein
C1A23_RS02605	COG0174	glutamine synthetase
C1A23_RS02625	COG3842	ATPase activity
C1A23_RS02630	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1A23_RS02635	COG1177	transmembrane transport
C1A23_RS02640	COG2258	MOSC domain
C1A23_RS02655	COG2050	protein possibly involved in aromatic compounds catabolism
C1A23_RS02660	COG0514	ATP-dependent DNA helicase (RecQ)
C1A23_RS02670	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C1A23_RS02680	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C1A23_RS02685	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1A23_RS02695	COG2239	Acts as a magnesium transporter
C1A23_RS02700	COG1648	precorrin-2 dehydrogenase activity
C1A23_RS02700	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1A23_RS02705	COG2116	formate transmembrane transporter activity
C1A23_RS02715	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1A23_RS02720	COG0842	Transport permease protein
C1A23_RS02725	COG0842	Transport permease protein
C1A23_RS02730	COG1131	(ABC) transporter
C1A23_RS02735	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS02745	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C1A23_RS02750	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C1A23_RS02760	COG0018	arginyl-trna synthetase
C1A23_RS02770	COG1595	DNA-templated transcription, initiation
C1A23_RS02775	COG3806	Anti-sigma factor
C1A23_RS02780	COG1968	undecaprenyl-diphosphatase activity
C1A23_RS02785	COG0667	Aldo Keto reductase
C1A23_RS02790	COG2017	converts alpha-aldose to the beta-anomer
C1A23_RS02795	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C1A23_RS02805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1A23_RS02810	COG1609	Transcriptional regulator
C1A23_RS02815	COG3250	beta-galactosidase activity
C1A23_RS02865	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1A23_RS02870	COG1288	antiporter activity
C1A23_RS02875	COG1438	arginine binding
C1A23_RS02880	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C1A23_RS02885	COG0540	Belongs to the ATCase OTCase family
C1A23_RS02900	COG0688	phosphatidylethanolamine metabolic process
C1A23_RS02910	COG3040	lipid binding
C1A23_RS02915	COG2207	Transcriptional regulator
C1A23_RS02920	COG1979	alcohol dehydrogenase
C1A23_RS02925	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C1A23_RS02930	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C1A23_RS02940	COG3681	Belongs to the UPF0597 family
C1A23_RS02950	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1A23_RS02955	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1A23_RS02960	COG0564	pseudouridine synthase activity
C1A23_RS02970	COG0542	response to heat
C1A23_RS02975	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C1A23_RS02985	COG2502	aspartate--ammonia ligase
C1A23_RS02990	COG1522	sequence-specific DNA binding
C1A23_RS03000	COG5413	integral membrane protein
C1A23_RS03010	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS03025	COG2205	protein histidine kinase activity
C1A23_RS03035	COG2204	response regulator
C1A23_RS03055	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C1A23_RS03085	COG0243	molybdopterin cofactor binding
C1A23_RS03090	COG3005	denitrification pathway
C1A23_RS03095	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C1A23_RS03115	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1A23_RS03120	COG0569	domain protein
C1A23_RS03125	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C1A23_RS03150	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C1A23_RS03165	COG0250	Participates in transcription elongation, termination and antitermination
C1A23_RS03170	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C1A23_RS03175	COG0081	regulation of translation
C1A23_RS03180	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C1A23_RS03185	COG0222	ribosome binding
C1A23_RS03190	COG0085	RNA polymerase activity
C1A23_RS03195	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C1A23_RS03200	COG2964	Protein conserved in bacteria
C1A23_RS03205	COG0251	oxidation-reduction process
C1A23_RS03215	COG2923	Belongs to the DsrF TusC family
C1A23_RS03220	COG2168	tRNA wobble position uridine thiolation
C1A23_RS03225	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C1A23_RS03230	COG0049	tRNA binding
C1A23_RS03235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C1A23_RS03240	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C1A23_RS03245	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1A23_RS03280	COG2252	PERMEase
C1A23_RS03285	COG2376	Dihydroxyacetone kinase
C1A23_RS03290	COG1461	Dihydroxyacetone kinase
C1A23_RS03305	COG3284	Transcriptional regulator
C1A23_RS03315	COG2957	Belongs to the agmatine deiminase family
C1A23_RS03320	COG4221	oxidoreductase activity
C1A23_RS03325	COG0628	permease
C1A23_RS03330	COG0494	nUDIX hydrolase
C1A23_RS03355	COG0753	catalase activity
C1A23_RS03360	COG1247	-acetyltransferase
C1A23_RS03380	COG3706	GGDEF domain
C1A23_RS03390	COG3842	ATPase activity
C1A23_RS03400	COG1175	transmembrane transport
C1A23_RS03430	COG0583	DNA-binding transcription factor activity
C1A23_RS03440	COG1741	Belongs to the pirin family
C1A23_RS03445	COG2259	Doxx family
C1A23_RS03450	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C1A23_RS03455	COG1074	ATP-dependent DNA helicase activity
C1A23_RS03460	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C1A23_RS03470	COG0346	lactoylglutathione lyase activity
C1A23_RS03520	COG2203	Gaf domain
C1A23_RS03520	COG3706	GGDEF domain
C1A23_RS03520	COG5001	Diguanylate cyclase
C1A23_RS03520	COG4251	negative regulation of phosphorylation
C1A23_RS03525	COG4771	TonB-dependent receptor
C1A23_RS03535	COG1278	Cold shock
C1A23_RS03575	COG2132	Multicopper oxidase
C1A23_RS03585	COG3039	Transposase
C1A23_RS03610	COG3039	Transposase
C1A23_RS03650	COG4974	Belongs to the 'phage' integrase family
C1A23_RS03655	COG0629	single-stranded DNA binding
C1A23_RS03660	COG2197	response regulator
C1A23_RS03665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C1A23_RS03675	COG3047	cAMP biosynthetic process
C1A23_RS03705	COG3135	benzoate transporter
C1A23_RS03710	COG1396	sequence-specific DNA binding
C1A23_RS03740	COG2926	Belongs to the UPF0265 family
C1A23_RS03750	COG3028	Belongs to the UPF0307 family
C1A23_RS03755	COG0312	modulator of DNA gyrase
C1A23_RS03760	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C1A23_RS03765	COG5007	Belongs to the BolA IbaG family
C1A23_RS03775	COG2854	intermembrane phospholipid transfer
C1A23_RS03780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1A23_RS03785	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C1A23_RS03790	COG1127	ABC transporter
C1A23_RS03795	COG0517	IMP dehydrogenase activity
C1A23_RS03795	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1A23_RS03800	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C1A23_RS03805	COG3117	lipopolysaccharide transmembrane transporter activity
C1A23_RS03810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C1A23_RS03815	COG1137	ATPase activity
C1A23_RS03820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C1A23_RS03830	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS03835	COG1660	Displays ATPase and GTPase activities
C1A23_RS03840	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS03860	COG3964	amidohydrolase
C1A23_RS03890	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1A23_RS03895	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C1A23_RS03905	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C1A23_RS03910	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C1A23_RS03915	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C1A23_RS03920	COG0723	plastoquinol--plastocyanin reductase activity
C1A23_RS03925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C1A23_RS03930	COG2857	Cytochrome c1
C1A23_RS03935	COG0625	glutathione transferase activity
C1A23_RS03940	COG2969	positive regulation of protein catabolic process
C1A23_RS03945	COG2823	Periplasmic or secreted lipoprotein
C1A23_RS03950	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1A23_RS03955	COG0792	nuclease activity
C1A23_RS03960	COG3107	peptidoglycan biosynthetic process
C1A23_RS03965	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C1A23_RS03975	COG2001	Belongs to the MraZ family
C1A23_RS03980	COG0275	rRNA processing
C1A23_RS03985	COG3116	cell division
C1A23_RS03990	COG0768	penicillin binding
C1A23_RS04000	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C1A23_RS04005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1A23_RS04010	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C1A23_RS04015	COG0772	Belongs to the SEDS family
C1A23_RS04020	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C1A23_RS04025	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1A23_RS04030	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C1A23_RS04035	COG0849	cell division
C1A23_RS04040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C1A23_RS04045	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C1A23_RS04055	COG0653	protein targeting
C1A23_RS04065	COG0494	nUDIX hydrolase
C1A23_RS04070	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C1A23_RS04075	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C1A23_RS04090	COG1459	type II secretion system
C1A23_RS04095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1A23_RS04125	COG2186	Transcriptional regulator
C1A23_RS04130	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C1A23_RS04135	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1A23_RS04140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C1A23_RS04150	COG0840	transmembrane signaling receptor activity
C1A23_RS04155	COG0840	transmembrane signaling receptor activity
C1A23_RS04160	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1A23_RS04165	COG1049	propionate catabolic process, 2-methylcitrate cycle
C1A23_RS04170	COG2200	EAL domain
C1A23_RS04180	COG1280	lysine exporter protein (LysE YggA)
C1A23_RS04190	COG0523	cobalamin synthesis protein
C1A23_RS04195	COG0477	Major facilitator Superfamily
C1A23_RS04210	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C1A23_RS04215	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C1A23_RS04255	COG3314	Sporulation integral membrane protein YlbJ
C1A23_RS04260	COG0784	Response regulator, receiver
C1A23_RS04260	COG0835	chemotaxis
C1A23_RS04265	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS04270	COG1444	tRNA N-acetyltransferase activity
C1A23_RS04295	COG1803	Methylglyoxal synthase
C1A23_RS04310	COG0252	asparaginase activity
C1A23_RS04330	COG1263	PTS System
C1A23_RS04330	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS04335	COG0366	Alpha amylase catalytic
C1A23_RS04340	COG0110	maltose O-acetyltransferase activity
C1A23_RS04345	COG1522	sequence-specific DNA binding
C1A23_RS04350	COG5006	permease, DMT superfamily
C1A23_RS04360	COG1012	belongs to the aldehyde dehydrogenase family
C1A23_RS04365	COG1177	transmembrane transport
C1A23_RS04370	COG1176	ABC-type spermidine putrescine transport system, permease component I
C1A23_RS04375	COG3842	ATPase activity
C1A23_RS04380	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C1A23_RS04385	COG0583	DNA-binding transcription factor activity
C1A23_RS04430	COG0297	glycogen (starch) synthase activity
C1A23_RS04435	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1A23_RS04440	COG2813	Specifically methylates the guanine in position
C1A23_RS04445	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C1A23_RS04450	COG4251	negative regulation of phosphorylation
C1A23_RS04450	COG3706	GGDEF domain
C1A23_RS04450	COG5001	Diguanylate cyclase
C1A23_RS04450	COG2203	Gaf domain
C1A23_RS04460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A23_RS04470	COG2995	paraquat-inducible protein a
C1A23_RS04475	COG3008	intermembrane lipid transfer
C1A23_RS04475	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C1A23_RS04480	COG3009	Protein conserved in bacteria
C1A23_RS04485	COG2885	chlorophyll binding
C1A23_RS04485	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
C1A23_RS04495	COG3240	lipase activity
C1A23_RS04500	COG3111	PFAM Bacterial OB fold (BOF) protein
C1A23_RS04510	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C1A23_RS04515	COG1194	a g-specific adenine glycosylase
C1A23_RS04525	COG3267	Type II secretory pathway component ExeA
C1A23_RS04525	COG3409	Peptidoglycan-binding domain 1 protein
C1A23_RS04530	COG0617	tRNA 3'-terminal CCA addition
C1A23_RS04545	COG1346	cytolysis
C1A23_RS04550	COG1380	Effector of murein hydrolase LrgA
C1A23_RS04555	COG0583	DNA-binding transcription factor activity
C1A23_RS04585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C1A23_RS04590	COG0306	phosphate transporter
C1A23_RS04595	COG1392	Phosphate transport regulator
C1A23_RS04610	COG1560	Kdo2-lipid A biosynthetic process
C1A23_RS04615	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C1A23_RS04615	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C1A23_RS04620	COG1538	Outer membrane efflux protein
C1A23_RS04625	COG0494	nUDIX hydrolase
C1A23_RS04630	COG3151	Protein conserved in bacteria
C1A23_RS04640	COG3150	esterase
C1A23_RS04645	COG1051	belongs to the nudix hydrolase family
C1A23_RS04660	COG1566	PFAM secretion protein HlyD family protein
C1A23_RS04665	COG1289	transmembrane transporter activity
C1A23_RS04680	COG0583	DNA-binding transcription factor activity
C1A23_RS04720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1A23_RS04740	COG0204	Acyl-transferase
C1A23_RS04745	COG1842	Phage shock protein A
C1A23_RS04760	COG2827	Endonuclease containing a URI domain
C1A23_RS04770	COG2962	Rard protein
C1A23_RS04775	COG1573	uracil-dna glycosylase
C1A23_RS04780	COG0697	spore germination
C1A23_RS04785	COG0583	DNA-binding transcription factor activity
C1A23_RS04790	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C1A23_RS04795	COG1121	(ABC) transporter
C1A23_RS04800	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C1A23_RS04820	COG0739	heme binding
C1A23_RS04835	COG3068	Protein conserved in bacteria
C1A23_RS04855	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C1A23_RS04860	COG1546	Belongs to the CinA family
C1A23_RS04865	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C1A23_RS04875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C1A23_RS04880	COG0527	aspartate kinase activity
C1A23_RS04885	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C1A23_RS04920	COG1686	Belongs to the peptidase S11 family
C1A23_RS04925	COG0586	Pfam SNARE associated Golgi protein
C1A23_RS04930	COG1253	flavin adenine dinucleotide binding
C1A23_RS04935	COG0525	valine-tRNA ligase activity
C1A23_RS04940	COG2927	DNA polymerase III (CHI subunit)
C1A23_RS04945	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1A23_RS04950	COG0795	lipopolysaccharide-transporting ATPase activity
C1A23_RS04955	COG0795	lipopolysaccharide-transporting ATPase activity
C1A23_RS04970	COG0582	viral genome integration into host DNA
C1A23_RS04985	COG3561	AntA/AntB antirepressor
C1A23_RS05025	COG0004	ammonium transporteR
C1A23_RS05030	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1A23_RS05040	COG2165	general secretion pathway protein
C1A23_RS05045	COG0084	hydrolase, TatD family'
C1A23_RS05050	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1A23_RS05060	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C1A23_RS05065	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C1A23_RS05070	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C1A23_RS05075	COG0813	purine-nucleoside phosphorylase activity
C1A23_RS05080	COG3447	MASE1 domain protein
C1A23_RS05080	COG5001	Diguanylate cyclase
C1A23_RS05080	COG5002	protein histidine kinase activity
C1A23_RS05090	COG0560	Phosphoserine phosphatase
C1A23_RS05115	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C1A23_RS05120	COG0776	regulation of translation
C1A23_RS05135	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1A23_RS05140	COG0735	belongs to the Fur family
C1A23_RS05165	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C1A23_RS05170	COG0513	Belongs to the DEAD box helicase family
C1A23_RS05175	COG3022	response to hydroperoxide
C1A23_RS05190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C1A23_RS05195	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C1A23_RS05200	COG0762	integral membrane protein
C1A23_RS05205	COG1872	DUF167
C1A23_RS05220	COG4166	transmembrane transport
C1A23_RS05240	COG1024	Enoyl-CoA hydratase
C1A23_RS05255	COG4221	oxidoreductase activity
C1A23_RS05260	COG0442	prolyl-tRNA aminoacylation
C1A23_RS05265	COG0840	transmembrane signaling receptor activity
C1A23_RS05270	COG0632	four-way junction helicase activity
C1A23_RS05275	COG2255	four-way junction helicase activity
C1A23_RS05280	COG1271	oxidase subunit
C1A23_RS05285	COG1294	oxidase, subunit
C1A23_RS05290	COG4890	Cyd operon protein YbgT
C1A23_RS05295	COG3790	cyd operon protein YbgE
C1A23_RS05300	COG0824	Thioesterase
C1A23_RS05305	COG0811	peptide transport
C1A23_RS05320	COG0823	Involved in the tonB-independent uptake of proteins
C1A23_RS05325	COG2885	chlorophyll binding
C1A23_RS05330	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C1A23_RS05405	COG0840	transmembrane signaling receptor activity
C1A23_RS05410	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C1A23_RS05415	COG0676	glucose-6-phosphate 1-epimerase activity
C1A23_RS05420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1A23_RS05425	COG1640	4-alpha-glucanotransferase
C1A23_RS05430	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C1A23_RS05450	COG1051	belongs to the nudix hydrolase family
C1A23_RS05455	COG2130	NADP-dependent
C1A23_RS05460	COG1764	response to oxidative stress
C1A23_RS05465	COG1846	Transcriptional regulator
C1A23_RS05495	COG0561	phosphatase activity
C1A23_RS05510	COG0733	neurotransmitter:sodium symporter activity
C1A23_RS05520	COG0733	neurotransmitter:sodium symporter activity
C1A23_RS05545	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1A23_RS05555	COG1794	racemase activity, acting on amino acids and derivatives
C1A23_RS05570	COG2731	YhcH YjgK YiaL family protein
C1A23_RS05580	COG0668	transmembrane transport
C1A23_RS05590	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1A23_RS05620	COG0583	DNA-binding transcription factor activity
C1A23_RS05625	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C1A23_RS05635	COG0488	(ABC) transporter
C1A23_RS05640	COG0517	IMP dehydrogenase activity
C1A23_RS05640	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C1A23_RS05645	COG1585	Membrane protein implicated in regulation of membrane protease activity
C1A23_RS05650	COG0330	HflC and HflK could
C1A23_RS05655	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1A23_RS05655	COG1648	precorrin-2 dehydrogenase activity
C1A23_RS05660	COG0175	sulfate reduction
C1A23_RS05665	COG2895	sulfate adenylyltransferase (ATP) activity
C1A23_RS05670	COG0471	metal ion transport
C1A23_RS05670	COG3273	potassium ion transport
C1A23_RS05675	COG0529	Catalyzes the synthesis of activated sulfate
C1A23_RS05695	COG0840	transmembrane signaling receptor activity
C1A23_RS05715	COG1136	(ABC) transporter
C1A23_RS05730	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C1A23_RS05750	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C1A23_RS05755	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C1A23_RS05760	COG0163	prenyltransferase activity
C1A23_RS05775	COG1131	(ABC) transporter
C1A23_RS05780	COG0842	Transport permease protein
C1A23_RS05785	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
C1A23_RS05790	COG1924	4 iron, 4 sulfur cluster binding
C1A23_RS05810	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C1A23_RS05815	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C1A23_RS05830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1A23_RS05835	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C1A23_RS05840	COG1489	DNA binding
C1A23_RS05850	COG1643	Atp-dependent helicase
C1A23_RS05855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1A23_RS05860	COG0346	lactoylglutathione lyase activity
C1A23_RS05870	COG2076	Multidrug Resistance protein
C1A23_RS05880	COG3437	response regulator, receiver
C1A23_RS05880	COG0784	Response regulator, receiver
C1A23_RS05890	COG0671	phosphoesterase, PA-phosphatase related
C1A23_RS05905	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C1A23_RS05910	COG0038	chloride channel
C1A23_RS05920	COG0316	Belongs to the HesB IscA family
C1A23_RS05950	COG2816	NAD+ diphosphatase activity
C1A23_RS05955	COG2205	protein histidine kinase activity
C1A23_RS05960	COG0745	RESPONSE REGULATOR receiver
C1A23_RS05965	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS05970	COG0577	efflux transmembrane transporter activity
C1A23_RS05970	COG1136	(ABC) transporter
C1A23_RS05975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS05980	COG1126	abc transporter atp-binding protein
C1A23_RS05985	COG0765	amino acid transport
C1A23_RS05990	COG0765	amino acid transport
C1A23_RS05995	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C1A23_RS06000	COG1505	serine-type exopeptidase activity
C1A23_RS06015	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS06020	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C1A23_RS06035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1A23_RS06040	COG4991	sh3 domain protein
C1A23_RS06055	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C1A23_RS06060	COG1940	carbohydrate kinase activity
C1A23_RS06065	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C1A23_RS06070	COG0126	phosphoglycerate kinase activity
C1A23_RS06080	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1A23_RS06090	COG4232	protein-disulfide reductase activity
C1A23_RS06120	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
C1A23_RS06130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C1A23_RS06135	COG1595	DNA-templated transcription, initiation
C1A23_RS06140	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C1A23_RS06155	COG0481	GTPase activity
C1A23_RS06160	COG0681	Belongs to the peptidase S26 family
C1A23_RS06165	COG0571	ribonuclease III activity
C1A23_RS06175	COG1381	Involved in DNA repair and RecF pathway recombination
C1A23_RS06180	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C1A23_RS06195	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1A23_RS06200	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS06205	COG3716	PTS system mannose fructose sorbose family IID component
C1A23_RS06215	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS06220	COG2222	sugar isomerase
C1A23_RS06230	COG1349	DNA-binding transcription factor activity
C1A23_RS06235	COG3023	N-Acetylmuramoyl-L-alanine amidase
C1A23_RS06240	COG4807	Protein conserved in bacteria
C1A23_RS06250	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C1A23_RS06255	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C1A23_RS06260	COG3956	TIGRFAM MazG family protein
C1A23_RS06265	COG0504	CTP synthase activity
C1A23_RS06270	COG0148	phosphopyruvate hydratase activity
C1A23_RS06275	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C1A23_RS06280	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C1A23_RS06290	COG0585	pseudouridine synthase activity
C1A23_RS06295	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C1A23_RS06300	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C1A23_RS06305	COG1238	metal cluster binding
C1A23_RS06320	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C1A23_RS06325	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C1A23_RS06330	COG1610	YqeY-like protein
C1A23_RS06335	COG0358	DNA primase activity
C1A23_RS06340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C1A23_RS06370	COG1484	DNA-dependent DNA replication
C1A23_RS06375	COG4584	PFAM Integrase catalytic
C1A23_RS06410	COG0151	Belongs to the GarS family
C1A23_RS06415	COG0138	bifunctional purine biosynthesis protein purh
C1A23_RS06425	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C1A23_RS06430	COG3036	rescue of stalled ribosome
C1A23_RS06435	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1A23_RS06440	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C1A23_RS06450	COG0673	inositol 2-dehydrogenase activity
C1A23_RS06460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1A23_RS06465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1A23_RS06480	COG0477	Major facilitator Superfamily
C1A23_RS06490	COG5433	transposase activity
C1A23_RS06500	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1A23_RS06505	COG1027	Aspartate ammonia-lyase
C1A23_RS06510	COG3030	protein affecting phage T7 exclusion by the F plasmid
C1A23_RS06515	COG0534	Mate efflux family protein
C1A23_RS06520	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C1A23_RS06525	COG0459	protein refolding
C1A23_RS06535	COG5001	Diguanylate cyclase
C1A23_RS06535	COG3300	MHYT domain
C1A23_RS06545	COG0564	pseudouridine synthase activity
C1A23_RS06550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C1A23_RS06585	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1A23_RS06595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C1A23_RS06605	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C1A23_RS06610	COG1178	ABC-type Fe3 transport system permease component
C1A23_RS06630	COG0066	3-isopropylmalate dehydratase activity
C1A23_RS06635	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C1A23_RS06640	COG0473	3-isopropylmalate dehydrogenase activity
C1A23_RS06645	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1A23_RS06655	COG0671	phosphoesterase, PA-phosphatase related
C1A23_RS06660	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C1A23_RS06670	COG0028	Belongs to the TPP enzyme family
C1A23_RS06680	COG0280	phosphate acetyltransferase
C1A23_RS06680	COG0857	belongs to the CobB CobQ family
C1A23_RS06685	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C1A23_RS06695	COG3013	Belongs to the UPF0304 family
C1A23_RS06700	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C1A23_RS06705	COG2716	regulation of RNA biosynthetic process
C1A23_RS06715	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C1A23_RS06720	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C1A23_RS06735	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
C1A23_RS06755	COG0784	Response regulator, receiver
C1A23_RS06755	COG5002	protein histidine kinase activity
C1A23_RS06755	COG2198	Histidine kinase
C1A23_RS06780	COG0840	transmembrane signaling receptor activity
C1A23_RS06790	COG1464	Belongs to the NlpA lipoprotein family
C1A23_RS06795	COG2011	ABC-type metal ion transport system permease component
C1A23_RS06800	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C1A23_RS06815	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
C1A23_RS06820	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C1A23_RS06820	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C1A23_RS06825	COG0802	atpase or kinase
C1A23_RS06835	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C1A23_RS06840	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C1A23_RS06845	COG1923	regulation of RNA biosynthetic process
C1A23_RS06850	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C1A23_RS06855	COG0330	HflC and HflK could
C1A23_RS06860	COG0330	HflC and HflK could
C1A23_RS06865	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C1A23_RS06870	COG0142	geranyltranstransferase activity
C1A23_RS06875	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C1A23_RS06880	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C1A23_RS06885	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C1A23_RS06890	COG3314	Sporulation integral membrane protein YlbJ
C1A23_RS06895	COG0318	PFAM AMP-dependent synthetase and ligase
C1A23_RS06910	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1A23_RS06915	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C1A23_RS06925	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C1A23_RS06930	COG2967	ApaG domain
C1A23_RS06935	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C1A23_RS06940	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C1A23_RS06950	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C1A23_RS06955	COG3178	'Phosphotransferase
C1A23_RS06960	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C1A23_RS06965	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C1A23_RS06970	COG2252	PERMEase
C1A23_RS06980	COG0488	(ABC) transporter
C1A23_RS07000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C1A23_RS07005	COG0741	lytic transglycosylase activity
C1A23_RS07025	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
C1A23_RS07030	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1A23_RS07035	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C1A23_RS07060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1A23_RS07070	COG3721	Heme iron utilization protein
C1A23_RS07075	COG0748	coenzyme F420 binding
C1A23_RS07095	COG4771	TonB-dependent receptor
C1A23_RS07105	COG2814	Major facilitator Superfamily
C1A23_RS07110	COG3655	Transcriptional regulator
C1A23_RS07120	COG2205	protein histidine kinase activity
C1A23_RS07120	COG2202	Pas domain
C1A23_RS07135	COG3397	chitin binding
C1A23_RS07140	COG2226	methyltransferase
C1A23_RS07150	COG1765	OsmC-like protein
C1A23_RS07165	COG3954	Phosphoribulokinase
C1A23_RS07170	COG2076	Multidrug Resistance protein
C1A23_RS07175	COG2076	Multidrug Resistance protein
C1A23_RS07180	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C1A23_RS07185	COG0726	polysaccharide deacetylase
C1A23_RS07190	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C1A23_RS07190	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C1A23_RS07195	COG0463	Glycosyl transferase, family 2
C1A23_RS07200	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1A23_RS07210	COG3089	Belongs to the UPF0270 family
C1A23_RS07215	COG5001	Diguanylate cyclase
C1A23_RS07215	COG4251	negative regulation of phosphorylation
C1A23_RS07215	COG2203	Gaf domain
C1A23_RS07215	COG3706	GGDEF domain
C1A23_RS07220	COG0429	hydrolase of the alpha beta-hydrolase fold
C1A23_RS07225	COG0784	Response regulator, receiver
C1A23_RS07225	COG0835	chemotaxis
C1A23_RS07235	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C1A23_RS07240	COG1047	Peptidyl-prolyl cis-trans
C1A23_RS07255	COG0545	Peptidyl-prolyl cis-trans isomerase
C1A23_RS07260	COG2204	response regulator
C1A23_RS07280	COG0737	Belongs to the 5'-nucleotidase family
C1A23_RS07290	COG2200	EAL domain
C1A23_RS07305	COG0305	Participates in initiation and elongation during chromosome replication
C1A23_RS07315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1A23_RS07325	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1A23_RS07330	COG0826	peptidase U32
C1A23_RS07335	COG2200	EAL domain
C1A23_RS07335	COG2203	Gaf domain
C1A23_RS07335	COG2199	diguanylate cyclase activity
C1A23_RS07355	COG3188	usher protein
C1A23_RS07360	COG3039	Transposase
C1A23_RS07370	COG2197	response regulator
C1A23_RS07400	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C1A23_RS07405	COG2201	protein-glutamate methylesterase activity
C1A23_RS07410	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C1A23_RS07435	COG0835	chemotaxis
C1A23_RS07445	COG0643	Histidine kinase
C1A23_RS07445	COG2198	Histidine kinase
C1A23_RS07460	COG0840	transmembrane signaling receptor activity
C1A23_RS07465	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1A23_RS07475	COG1280	lysine exporter protein (LysE YggA)
C1A23_RS07480	COG0826	peptidase U32
C1A23_RS07505	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C1A23_RS07530	COG0300	oxidoreductase activity
C1A23_RS07585	COG0840	transmembrane signaling receptor activity
C1A23_RS07625	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1A23_RS07635	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS07640	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS07710	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1A23_RS07740	COG1484	DNA-dependent DNA replication
C1A23_RS07745	COG4584	PFAM Integrase catalytic
C1A23_RS07760	COG4133	protoheme IX ABC transporter activity
C1A23_RS07785	COG2003	Belongs to the UPF0758 family
C1A23_RS07830	COG5377	YqaJ viral recombinase family
C1A23_RS07860	COG0077	Prephenate dehydratase
C1A23_RS07860	COG1605	Chorismate mutase
C1A23_RS07890	COG3272	Protein of unknown function (DUF1722)
C1A23_RS07895	COG0789	Transcriptional regulator
C1A23_RS07900	COG0415	Belongs to the DNA photolyase family
C1A23_RS07910	COG4221	oxidoreductase activity
C1A23_RS07925	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C1A23_RS07950	COG0783	Belongs to the Dps family
C1A23_RS07955	COG1151	hydroxylamine reductase activity
C1A23_RS07965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C1A23_RS07970	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1A23_RS07970	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1A23_RS07990	COG2771	luxR family
C1A23_RS08045	COG1484	DNA-dependent DNA replication
C1A23_RS08050	COG4584	PFAM Integrase catalytic
C1A23_RS08060	COG0693	protein deglycase activity
C1A23_RS08065	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C1A23_RS08070	COG1666	GTP binding
C1A23_RS08075	COG3248	Nucleoside-binding outer membrane protein
C1A23_RS08080	COG2211	Major facilitator Superfamily
C1A23_RS08090	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1A23_RS08100	COG2813	Specifically methylates the guanine in position
C1A23_RS08105	COG0271	Belongs to the BolA IbaG family
C1A23_RS08110	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C1A23_RS08115	COG1805	sodium ion transport
C1A23_RS08120	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C1A23_RS08125	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C1A23_RS08130	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C1A23_RS08135	COG2871	sodium ion transport
C1A23_RS08140	COG1477	protein flavinylation
C1A23_RS08155	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C1A23_RS08160	COG0840	transmembrane signaling receptor activity
C1A23_RS08165	COG0583	DNA-binding transcription factor activity
C1A23_RS08175	COG2363	Small membrane protein
C1A23_RS08180	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C1A23_RS08190	COG0473	3-isopropylmalate dehydrogenase activity
C1A23_RS08195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1A23_RS08200	COG1611	Belongs to the LOG family
C1A23_RS08215	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C1A23_RS08215	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C1A23_RS08225	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C1A23_RS08250	COG3098	single-species biofilm formation
C1A23_RS08255	COG0564	pseudouridine synthase activity
C1A23_RS08265	COG4580	involved in the transport of maltose and maltodextrins
C1A23_RS08275	COG1263	PTS System
C1A23_RS08275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS08285	COG2171	N-acyltransferase activity
C1A23_RS08290	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C1A23_RS08295	COG0024	Methionine aminopeptidase
C1A23_RS08300	COG0052	Belongs to the universal ribosomal protein uS2 family
C1A23_RS08305	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C1A23_RS08310	COG0528	UMP kinase activity
C1A23_RS08315	COG0233	cytoplasmic translational termination
C1A23_RS08320	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C1A23_RS08325	COG0575	Belongs to the CDS family
C1A23_RS08330	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C1A23_RS08335	COG0750	zinc metalloprotease
C1A23_RS08350	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1A23_RS08355	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C1A23_RS08360	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1A23_RS08365	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1A23_RS08370	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C1A23_RS08380	COG0825	malonyl-CoA metabolic process
C1A23_RS08385	COG3710	Transcriptional regulator
C1A23_RS08390	COG0531	amino acid
C1A23_RS08395	COG1982	Orn Lys Arg decarboxylase major
C1A23_RS08400	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C1A23_RS08415	COG0814	amino acid
C1A23_RS08430	COG1073	alpha beta
C1A23_RS08435	COG1073	alpha beta
C1A23_RS08445	COG0531	amino acid
C1A23_RS08455	COG0488	(ABC) transporter
C1A23_RS08465	COG3590	peptidase
C1A23_RS08475	COG3706	GGDEF domain
C1A23_RS08510	COG0366	Alpha amylase catalytic
C1A23_RS08525	COG0463	Glycosyl transferase, family 2
C1A23_RS08540	COG2989	Protein conserved in bacteria
C1A23_RS08545	COG3108	Peptidase M15
C1A23_RS08555	COG2860	membrane
C1A23_RS08565	COG1196	nuclear chromosome segregation
C1A23_RS08570	COG3115	cell septum assembly
C1A23_RS08575	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C1A23_RS08585	COG1328	CTP reductase activity
C1A23_RS08590	COG0602	queuosine metabolic process
C1A23_RS08620	COG1566	PFAM secretion protein HlyD family protein
C1A23_RS08625	COG1846	Transcriptional regulator
C1A23_RS08640	COG0281	malic enzyme
C1A23_RS08645	COG3290	protein histidine kinase activity
C1A23_RS08650	COG4565	transcriptional regulatory protein
C1A23_RS08655	COG0697	spore germination
C1A23_RS08670	COG3284	Transcriptional regulator
C1A23_RS08675	COG1960	acyl-CoA dehydrogenase activity
C1A23_RS08680	COG1804	L-carnitine dehydratase bile acid-inducible protein F
C1A23_RS08685	COG0346	lactoylglutathione lyase activity
C1A23_RS08690	COG0745	RESPONSE REGULATOR receiver
C1A23_RS08695	COG5002	protein histidine kinase activity
C1A23_RS08720	COG3142	Participates in the control of copper homeostasis
C1A23_RS08725	COG0545	Peptidyl-prolyl cis-trans isomerase
C1A23_RS08730	COG1131	(ABC) transporter
C1A23_RS08750	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C1A23_RS08770	COG0019	diaminopimelate decarboxylase activity
C1A23_RS08775	COG1115	amino acid carrier protein
C1A23_RS08780	COG0095	Lipoate-protein ligase
C1A23_RS08800	COG0534	Mate efflux family protein
C1A23_RS08810	COG0281	malic enzyme
C1A23_RS08825	COG5433	transposase activity
C1A23_RS08845	COG0733	neurotransmitter:sodium symporter activity
C1A23_RS08850	COG1752	Esterase of the alpha-beta hydrolase superfamily
C1A23_RS08860	COG1566	PFAM secretion protein HlyD family protein
C1A23_RS08865	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS08875	COG1032	radical SAM domain protein
C1A23_RS08880	COG2801	Transposase and inactivated derivatives
C1A23_RS08905	COG0673	inositol 2-dehydrogenase activity
C1A23_RS08915	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C1A23_RS08920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1A23_RS08925	COG1196	nuclear chromosome segregation
C1A23_RS08925	COG0739	heme binding
C1A23_RS08925	COG0741	lytic transglycosylase activity
C1A23_RS08930	COG0366	Alpha amylase catalytic
C1A23_RS08950	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1A23_RS08960	COG0788	formyltetrahydrofolate deformylase activity
C1A23_RS08965	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1A23_RS08975	COG3118	belongs to the thioredoxin family
C1A23_RS08985	COG0791	NLP P60 protein
C1A23_RS08990	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C1A23_RS09005	COG1388	LysM domain
C1A23_RS09005	COG1376	ErfK ybiS ycfS ynhG family protein
C1A23_RS09015	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS09020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS09025	COG0745	RESPONSE REGULATOR receiver
C1A23_RS09030	COG5002	protein histidine kinase activity
C1A23_RS09050	COG4869	propanediol catabolic process
C1A23_RS09060	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1A23_RS09065	COG1882	Formate acetyltransferase
C1A23_RS09070	COG1454	alcohol dehydrogenase
C1A23_RS09070	COG1012	belongs to the aldehyde dehydrogenase family
C1A23_RS09080	COG1012	belongs to the aldehyde dehydrogenase family
C1A23_RS09080	COG1454	alcohol dehydrogenase
C1A23_RS09115	COG0583	DNA-binding transcription factor activity
C1A23_RS09120	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C1A23_RS09125	COG0243	molybdopterin cofactor binding
C1A23_RS09135	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C1A23_RS09145	COG1960	acyl-CoA dehydrogenase activity
C1A23_RS09150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS09160	COG0469	pyruvate kinase activity
C1A23_RS09165	COG1737	Transcriptional regulator
C1A23_RS09185	COG2274	protein secretion by the type I secretion system
C1A23_RS09195	COG2274	protein secretion by the type I secretion system
C1A23_RS09220	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
C1A23_RS09220	COG3064	Membrane
C1A23_RS09220	COG1073	alpha beta
C1A23_RS09230	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1A23_RS09240	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS09250	COG1414	Transcriptional regulator
C1A23_RS09255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1A23_RS09260	COG0800	Aldolase
C1A23_RS09265	COG2731	YhcH YjgK YiaL family protein
C1A23_RS09285	COG1677	Flagellar hook-basal body complex protein FliE
C1A23_RS09295	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C1A23_RS09350	COG1684	flagellar biosynthetic protein fliR
C1A23_RS09360	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C1A23_RS09385	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C1A23_RS09390	COG2198	Histidine kinase
C1A23_RS09390	COG0784	Response regulator, receiver
C1A23_RS09390	COG0643	Histidine kinase
C1A23_RS09395	COG2201	protein-glutamate methylesterase activity
C1A23_RS09400	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1A23_RS09405	COG1360	Flagellar Motor Protein
C1A23_RS09410	COG1192	Involved in chromosome partitioning
C1A23_RS09420	COG0835	chemotaxis
C1A23_RS09435	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1A23_RS09440	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1A23_RS09445	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C1A23_RS09450	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C1A23_RS09455	COG1138	Cytochrome C-type biogenesis protein
C1A23_RS09460	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1A23_RS09465	COG4235	cytochrome complex assembly
C1A23_RS09465	COG3088	subunit of a heme lyase
C1A23_RS09470	COG4235	cytochrome complex assembly
C1A23_RS09470	COG3088	subunit of a heme lyase
C1A23_RS09485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C1A23_RS09490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1A23_RS09490	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1A23_RS09505	COG0259	pyridoxamine-phosphate oxidase activity
C1A23_RS09510	COG0625	glutathione transferase activity
C1A23_RS09520	COG3153	acetyltransferase
C1A23_RS09525	COG2850	peptidyl-arginine hydroxylation
C1A23_RS09530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C1A23_RS09535	COG2915	High frequency lysogenization protein hflD homolog
C1A23_RS09540	COG0482	sulfurtransferase activity
C1A23_RS09550	COG1187	pseudouridine synthase activity
C1A23_RS09560	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1A23_RS09570	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1A23_RS09570	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS09570	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1A23_RS09585	COG3385	transposase activity
C1A23_RS09595	COG0456	acetyltransferase
C1A23_RS09605	COG0789	Transcriptional regulator
C1A23_RS09610	COG1902	pentaerythritol trinitrate reductase activity
C1A23_RS09610	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1A23_RS09615	COG1609	Transcriptional regulator
C1A23_RS09620	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS09620	COG1263	PTS System
C1A23_RS09625	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1A23_RS09640	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1A23_RS09660	COG2207	Transcriptional regulator
C1A23_RS09665	COG0538	isocitrate dehydrogenase activity
C1A23_RS09675	COG3048	D-serine ammonia-lyase activity
C1A23_RS09680	COG0583	DNA-binding transcription factor activity
C1A23_RS09720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS09725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS09805	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
C1A23_RS09815	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1A23_RS09825	COG1715	Restriction endonuclease
C1A23_RS09875	COG2003	Belongs to the UPF0758 family
C1A23_RS09910	COG5377	YqaJ viral recombinase family
C1A23_RS09920	COG3311	Transcriptional regulator
C1A23_RS09925	COG4983	Phage plasmid primase, P4 family domain protein
C1A23_RS09935	COG2916	Histone family protein nucleoid-structuring protein H-NS
C1A23_RS09940	COG0582	viral genome integration into host DNA
C1A23_RS09950	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C1A23_RS09955	COG2867	negative regulation of translational initiation
C1A23_RS09960	COG2914	Belongs to the UPF0125 (RnfH) family
C1A23_RS09965	COG0702	epimerase
C1A23_RS09970	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1A23_RS09975	COG1454	alcohol dehydrogenase
C1A23_RS09985	COG0564	pseudouridine synthase activity
C1A23_RS10015	COG1280	lysine exporter protein (LysE YggA)
C1A23_RS10025	COG3263	regulation of cellular component size
C1A23_RS10035	COG3263	regulation of cellular component size
C1A23_RS10045	COG1876	peptidase activity
C1A23_RS10050	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1A23_RS10055	COG1393	Belongs to the ArsC family
C1A23_RS10060	COG0583	DNA-binding transcription factor activity
C1A23_RS10070	COG3069	C4-dicarboxylate transmembrane transporter activity
C1A23_RS10085	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C1A23_RS10090	COG0017	Asparaginyl-tRNA synthetase
C1A23_RS10110	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C1A23_RS10115	COG0156	8-amino-7-oxononanoate synthase activity
C1A23_RS10120	COG1073	alpha beta
C1A23_RS10120	COG2226	methyltransferase
C1A23_RS10125	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C1A23_RS10130	COG0501	Belongs to the peptidase M48B family
C1A23_RS10140	COG3217	Mosc domain protein beta barrel domain protein
C1A23_RS10140	COG0633	Ferredoxin
C1A23_RS10140	COG0633	Ferredoxin
C1A23_RS10140	COG3217	Mosc domain protein beta barrel domain protein
C1A23_RS10150	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C1A23_RS10150	COG1013	pyruvate-flavodoxin oxidoreductase activity
C1A23_RS10150	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C1A23_RS10150	COG0674	pyruvate-flavodoxin oxidoreductase activity
C1A23_RS10165	COG0534	Mate efflux family protein
C1A23_RS10205	COG1309	transcriptional regulator
C1A23_RS10220	COG0791	NLP P60 protein
C1A23_RS10230	COG0583	DNA-binding transcription factor activity
C1A23_RS10235	COG0450	alkyl hydroperoxide reductase
C1A23_RS10255	COG0500	methyltransferase
C1A23_RS10260	COG4106	trans-aconitate 2-methyltransferase activity
C1A23_RS10265	COG1801	Protein of unknown function DUF72
C1A23_RS10270	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C1A23_RS10275	COG0217	transcriptional regulatory protein
C1A23_RS10280	COG2194	sulfuric ester hydrolase activity
C1A23_RS10285	COG1846	Transcriptional regulator
C1A23_RS10285	COG1940	carbohydrate kinase activity
C1A23_RS10290	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1A23_RS10295	COG0363	glucosamine-6-phosphate deaminase activity
C1A23_RS10300	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS10300	COG1263	PTS System
C1A23_RS10300	COG2190	(PTS) system
C1A23_RS10310	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1A23_RS10315	COG0735	belongs to the Fur family
C1A23_RS10325	COG0716	FMN binding
C1A23_RS10340	COG0596	Alpha beta hydrolase
C1A23_RS10345	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C1A23_RS10350	COG0033	Phosphoglucomutase
C1A23_RS10360	COG1846	Transcriptional regulator
C1A23_RS10375	COG2951	lytic endotransglycosylase activity
C1A23_RS10380	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C1A23_RS10385	COG4136	ATPase activity
C1A23_RS10390	COG4135	transport system, permease component
C1A23_RS10395	COG4134	Bacterial extracellular solute-binding protein
C1A23_RS10405	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1A23_RS10415	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1A23_RS10420	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1A23_RS10430	COG0729	surface antigen
C1A23_RS10435	COG2911	Protein conserved in bacteria
C1A23_RS10455	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C1A23_RS10465	COG0741	lytic transglycosylase activity
C1A23_RS10480	COG1607	acyl-coa hydrolase
C1A23_RS10490	COG3021	interspecies interaction between organisms
C1A23_RS10495	COG0741	lytic transglycosylase activity
C1A23_RS10495	COG1388	LysM domain
C1A23_RS10500	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1A23_RS10505	COG2226	methyltransferase
C1A23_RS10510	COG0328	RNA-DNA hybrid ribonuclease activity
C1A23_RS10525	COG3437	response regulator, receiver
C1A23_RS10525	COG0784	Response regulator, receiver
C1A23_RS10530	COG1960	acyl-CoA dehydrogenase activity
C1A23_RS10535	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C1A23_RS10540	COG0121	glutamine amidotransferase
C1A23_RS10570	COG2197	response regulator
C1A23_RS10575	COG3850	Histidine kinase
C1A23_RS10580	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C1A23_RS10585	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1A23_RS10585	COG1149	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1A23_RS10595	COG0243	molybdopterin cofactor binding
C1A23_RS10600	COG0437	4 iron, 4 sulfur cluster binding
C1A23_RS10605	COG0348	domain, Protein
C1A23_RS10615	COG3005	denitrification pathway
C1A23_RS10620	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1A23_RS10625	COG0315	cyclic pyranopterin monophosphate synthase activity
C1A23_RS10630	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C1A23_RS10635	COG0314	molybdopterin synthase activity
C1A23_RS10650	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C1A23_RS10655	COG2267	carboxylic ester hydrolase activity
C1A23_RS10660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1A23_RS10670	COG0302	gtp cyclohydrolase
C1A23_RS10675	COG0840	transmembrane signaling receptor activity
C1A23_RS10680	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C1A23_RS10685	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C1A23_RS10695	COG0583	DNA-binding transcription factor activity
C1A23_RS10725	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1A23_RS10745	COG1166	arginine decarboxylase activity
C1A23_RS10765	COG0814	amino acid
C1A23_RS10775	COG3681	Belongs to the UPF0597 family
C1A23_RS10780	COG2964	Protein conserved in bacteria
C1A23_RS10790	COG1403	HNH endonuclease
C1A23_RS10800	COG0346	lactoylglutathione lyase activity
C1A23_RS10820	COG1187	pseudouridine synthase activity
C1A23_RS10830	COG2807	transmembrane transport
C1A23_RS10840	COG0583	DNA-binding transcription factor activity
C1A23_RS10845	COG2271	Major facilitator Superfamily
C1A23_RS10875	COG2979	Protein of unknown function (DUF533)
C1A23_RS10885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1A23_RS10890	COG1271	oxidase subunit
C1A23_RS10895	COG1294	oxidase, subunit
C1A23_RS10905	COG2814	Major facilitator Superfamily
C1A23_RS10910	COG0656	L-ascorbic acid biosynthetic process
C1A23_RS10940	COG4584	PFAM Integrase catalytic
C1A23_RS10945	COG1484	DNA-dependent DNA replication
C1A23_RS10955	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C1A23_RS10960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C1A23_RS10965	COG2271	Major facilitator Superfamily
C1A23_RS10970	COG1349	DNA-binding transcription factor activity
C1A23_RS10985	COG0584	glycerophosphoryl diester phosphodiesterase
C1A23_RS10990	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1A23_RS10995	COG0287	Prephenate dehydrogenase
C1A23_RS10995	COG1605	Chorismate mutase
C1A23_RS11000	COG0583	DNA-binding transcription factor activity
C1A23_RS11005	COG3085	chromosome segregation
C1A23_RS11010	COG4574	serine-type endopeptidase inhibitor activity
C1A23_RS11030	COG1770	oligopeptidase
C1A23_RS11035	COG4771	TonB-dependent receptor
C1A23_RS11040	COG3083	sulfuric ester hydrolase activity
C1A23_RS11045	COG3082	Protein of unknown function (DUF1414)
C1A23_RS11050	COG3081	Nucleoid-associated protein
C1A23_RS11060	COG1175	transmembrane transport
C1A23_RS11065	COG3833	ABC-type maltose transport systems, permease component
C1A23_RS11070	COG3842	ATPase activity
C1A23_RS11090	COG0425	Belongs to the sulfur carrier protein TusA family
C1A23_RS11095	COG4783	chaperone-mediated protein folding
C1A23_RS11100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1A23_RS11105	COG1393	Belongs to the ArsC family
C1A23_RS11120	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C1A23_RS11125	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C1A23_RS11130	COG2431	L-lysine efflux transmembrane transporter activity
C1A23_RS11140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS11160	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1A23_RS11170	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1A23_RS11175	COG2373	Large extracellular alpha-helical protein
C1A23_RS11180	COG4953	penicillin-binding protein 1C
C1A23_RS11190	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1A23_RS11190	COG0301	tRNA thio-modification
C1A23_RS11245	COG1083	cytidylyl-transferase
C1A23_RS11265	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C1A23_RS11270	COG2089	acid synthase
C1A23_RS11280	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C1A23_RS11290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1A23_RS11300	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C1A23_RS11325	COG0483	inositol monophosphate 1-phosphatase activity
C1A23_RS11335	COG0625	glutathione transferase activity
C1A23_RS11340	COG2814	Major facilitator Superfamily
C1A23_RS11360	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1A23_RS11365	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1A23_RS11370	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C1A23_RS11375	COG0509	glycine decarboxylation via glycine cleavage system
C1A23_RS11380	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1A23_RS11380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C1A23_RS11395	COG0640	Transcriptional regulator
C1A23_RS11400	COG0798	PFAM Bile acid sodium symporter
C1A23_RS11405	COG1393	Belongs to the ArsC family
C1A23_RS11425	COG3634	alkyl hydroperoxide reductase activity
C1A23_RS11435	COG0517	IMP dehydrogenase activity
C1A23_RS11440	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C1A23_RS11445	COG0343	queuine tRNA-ribosyltransferase activity
C1A23_RS11450	COG1862	Preprotein translocase
C1A23_RS11455	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1A23_RS11460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1A23_RS11475	COG0826	peptidase U32
C1A23_RS11480	COG0826	peptidase U32
C1A23_RS11495	COG3154	lipid carrier protein
C1A23_RS11515	COG1104	cysteine desulfurase activity
C1A23_RS11520	COG0822	iron-sulfur transferase activity
C1A23_RS11530	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C1A23_RS11535	COG0443	Heat shock 70 kDa protein
C1A23_RS11540	COG0633	Ferredoxin
C1A23_RS11550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1A23_RS11555	COG0105	UTP biosynthetic process
C1A23_RS11560	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C1A23_RS11570	COG1426	Protein conserved in bacteria
C1A23_RS11575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C1A23_RS11580	COG0124	histidyl-tRNA synthetase
C1A23_RS11585	COG2976	Protein conserved in bacteria
C1A23_RS11590	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1A23_RS11595	COG1160	GTP binding
C1A23_RS11600	COG1645	bacterial-type flagellum-dependent swarming motility
C1A23_RS11610	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1A23_RS11615	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C1A23_RS11615	COG0047	phosphoribosylformylglycinamidine synthase activity
C1A23_RS11620	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1A23_RS11620	COG2199	diguanylate cyclase activity
C1A23_RS11635	COG1007	ATP synthesis coupled electron transport
C1A23_RS11640	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1A23_RS11650	COG0713	ATP synthesis coupled electron transport
C1A23_RS11655	COG0839	Belongs to the complex I subunit 6 family
C1A23_RS11660	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1A23_RS11665	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C1A23_RS11670	COG1034	ATP synthesis coupled electron transport
C1A23_RS11685	COG0649	NAD binding
C1A23_RS11685	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1A23_RS11690	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1A23_RS11695	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1A23_RS11700	COG1360	Flagellar Motor Protein
C1A23_RS11705	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1A23_RS11720	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C1A23_RS11740	COG0724	RNA recognition motif
C1A23_RS11745	COG4989	oxidoreductase activity
C1A23_RS11770	COG3437	response regulator, receiver
C1A23_RS11775	COG0583	DNA-binding transcription factor activity
C1A23_RS11785	COG3300	MHYT domain
C1A23_RS11785	COG5001	Diguanylate cyclase
C1A23_RS11810	COG0583	DNA-binding transcription factor activity
C1A23_RS11820	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C1A23_RS11825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C1A23_RS11830	COG0539	negative regulation of cytoplasmic translation
C1A23_RS11835	COG0776	regulation of translation
C1A23_RS11845	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C1A23_RS11850	COG0284	orotidine-5'-phosphate decarboxylase activity
C1A23_RS11865	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C1A23_RS11870	COG0602	queuosine metabolic process
C1A23_RS11875	COG3530	Putative quorum-sensing-regulated virulence factor
C1A23_RS11880	COG2096	Adenosyltransferase
C1A23_RS11885	COG2916	Histone family protein nucleoid-structuring protein H-NS
C1A23_RS11890	COG1757	Na H antiporter
C1A23_RS11895	COG1435	thymidine kinase activity
C1A23_RS11925	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1A23_RS11930	COG0840	transmembrane signaling receptor activity
C1A23_RS11940	COG2201	protein-glutamate methylesterase activity
C1A23_RS11950	COG0835	chemotaxis
C1A23_RS11955	COG0840	transmembrane signaling receptor activity
C1A23_RS11960	COG2198	Histidine kinase
C1A23_RS11960	COG0643	Histidine kinase
C1A23_RS11970	COG0745	RESPONSE REGULATOR receiver
C1A23_RS11975	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C1A23_RS11980	COG0437	4 iron, 4 sulfur cluster binding
C1A23_RS11985	COG5557	Pfam Polysulphide reductase, NrfD
C1A23_RS11990	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C1A23_RS11995	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C1A23_RS12010	COG0601	transmembrane transport
C1A23_RS12015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1A23_RS12025	COG3842	ATPase activity
C1A23_RS12030	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C1A23_RS12035	COG0375	protein maturation
C1A23_RS12040	COG0309	Hydrogenase expression formation protein (HypE)
C1A23_RS12050	COG0298	carbon dioxide binding
C1A23_RS12055	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C1A23_RS12065	COG1921	L-seryl-tRNASec selenium transferase activity
C1A23_RS12070	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C1A23_RS12080	COG3260	NADH ubiquinone oxidoreductase 20
C1A23_RS12085	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1A23_RS12090	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C1A23_RS12090	COG3261	NADH dehydrogenase
C1A23_RS12095	COG0650	Formate hydrogenlyase subunit 4
C1A23_RS12100	COG0651	ATP synthesis coupled electron transport
C1A23_RS12105	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1A23_RS12110	COG3158	transport of potassium into the cell
C1A23_RS12120	COG3039	Transposase
C1A23_RS12125	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1A23_RS12155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C1A23_RS12165	COG0326	Molecular chaperone. Has ATPase activity
C1A23_RS12175	COG0563	adenylate kinase activity
C1A23_RS12180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C1A23_RS12190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1A23_RS12205	COG3300	MHYT domain
C1A23_RS12205	COG5001	Diguanylate cyclase
C1A23_RS12210	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1A23_RS12230	COG1021	2,3-dihydroxybenzoate-AMP ligase
C1A23_RS12235	COG1535	isochorismatase
C1A23_RS12235	COG3433	isochorismatase activity
C1A23_RS12240	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1A23_RS12245	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS12255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C1A23_RS12260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C1A23_RS12270	COG1120	ATPase activity
C1A23_RS12275	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1A23_RS12280	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C1A23_RS12285	COG4771	TonB-dependent receptor
C1A23_RS12310	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C1A23_RS12310	COG0644	oxidoreductase
C1A23_RS12335	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C1A23_RS12340	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C1A23_RS12345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1A23_RS12360	COG1570	exodeoxyribonuclease VII activity
C1A23_RS12365	COG0697	spore germination
C1A23_RS12385	COG3158	transport of potassium into the cell
C1A23_RS12390	COG0516	GMP reductase activity
C1A23_RS12390	COG0517	IMP dehydrogenase activity
C1A23_RS12395	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1A23_RS12395	COG0519	Catalyzes the synthesis of GMP from XMP
C1A23_RS12410	COG4584	PFAM Integrase catalytic
C1A23_RS12415	COG1484	DNA-dependent DNA replication
C1A23_RS12460	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1A23_RS12510	COG2062	phosphohistidine phosphatase, SixA
C1A23_RS12520	COG0697	spore germination
C1A23_RS12525	COG4166	transmembrane transport
C1A23_RS12530	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C1A23_RS12535	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C1A23_RS12545	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1A23_RS12550	COG1136	(ABC) transporter
C1A23_RS12555	COG4591	ABC-type transport system involved in lipoprotein release permease component
C1A23_RS12560	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C1A23_RS12575	COG0544	peptidyl-prolyl cis-trans isomerase activity
C1A23_RS12580	COG0740	serine-type endopeptidase activity
C1A23_RS12585	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C1A23_RS12590	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C1A23_RS12595	COG0776	regulation of translation
C1A23_RS12600	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C1A23_RS12605	COG0488	(ABC) transporter
C1A23_RS12610	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C1A23_RS12615	COG3162	membrane
C1A23_RS12630	COG1024	Enoyl-CoA hydratase
C1A23_RS12630	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1A23_RS12635	COG1115	amino acid carrier protein
C1A23_RS12650	COG1584	GPR1 FUN34 yaaH family protein
C1A23_RS12685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C1A23_RS12690	COG1960	acyl-CoA dehydrogenase activity
C1A23_RS12700	COG1960	acyl-CoA dehydrogenase activity
C1A23_RS12705	COG1024	Enoyl-CoA hydratase
C1A23_RS12710	COG1024	Enoyl-CoA hydratase
C1A23_RS12720	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS12730	COG0730	response to heat
C1A23_RS12750	COG5001	Diguanylate cyclase
C1A23_RS12750	COG3300	MHYT domain
C1A23_RS12755	COG0583	DNA-binding transcription factor activity
C1A23_RS12760	COG2723	6-phospho-beta-galactosidase activity
C1A23_RS12765	COG3300	MHYT domain
C1A23_RS12765	COG5001	Diguanylate cyclase
C1A23_RS12775	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1A23_RS12785	COG0583	DNA-binding transcription factor activity
C1A23_RS12800	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C1A23_RS12805	COG0673	inositol 2-dehydrogenase activity
C1A23_RS12810	COG0583	DNA-binding transcription factor activity
C1A23_RS12820	COG1560	Kdo2-lipid A biosynthetic process
C1A23_RS12825	COG1560	Kdo2-lipid A biosynthetic process
C1A23_RS12850	COG0417	DNA replication proofreading
C1A23_RS12880	COG0534	Mate efflux family protein
C1A23_RS12890	COG0307	riboflavin synthase, alpha
C1A23_RS12900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A23_RS12905	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C1A23_RS12910	COG0697	spore germination
C1A23_RS12915	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C1A23_RS12955	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C1A23_RS12960	COG3099	Belongs to the UPF0263 family
C1A23_RS12965	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C1A23_RS12970	COG2894	cell division
C1A23_RS12975	COG0850	regulation of cytokinetic process
C1A23_RS12980	COG3100	YcgL domain-containing protein
C1A23_RS12985	COG2951	lytic endotransglycosylase activity
C1A23_RS12990	COG1760	l-serine dehydratase
C1A23_RS13000	COG1760	l-serine dehydratase
C1A23_RS13005	COG3123	guanosine phosphorylase activity
C1A23_RS13025	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C1A23_RS13030	COG2067	long-chain fatty acid transport protein
C1A23_RS13045	COG1595	DNA-templated transcription, initiation
C1A23_RS13075	COG0714	Associated with various cellular activities
C1A23_RS13080	COG0183	Belongs to the thiolase family
C1A23_RS13085	COG1024	Enoyl-CoA hydratase
C1A23_RS13085	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1A23_RS13105	COG3829	transcription factor binding
C1A23_RS13110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C1A23_RS13115	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
C1A23_RS13120	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C1A23_RS13130	COG0549	Belongs to the carbamate kinase family
C1A23_RS13135	COG0697	spore germination
C1A23_RS13140	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
C1A23_RS13140	COG3608	succinylglutamate desuccinylase aspartoacylase
C1A23_RS13145	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C1A23_RS13150	COG2068	MobA-Related Protein
C1A23_RS13160	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C1A23_RS13160	COG0493	'glutamate synthase
C1A23_RS13165	COG0402	S-adenosylhomocysteine deaminase activity
C1A23_RS13170	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C1A23_RS13175	COG2080	2 iron, 2 sulfur cluster binding
C1A23_RS13175	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1A23_RS13180	COG2233	PERMEase
C1A23_RS13185	COG0402	S-adenosylhomocysteine deaminase activity
C1A23_RS13190	COG2252	PERMEase
C1A23_RS13195	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C1A23_RS13200	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
C1A23_RS13205	COG2080	2 iron, 2 sulfur cluster binding
C1A23_RS13215	COG3134	Outer membrane lipoprotein
C1A23_RS13225	COG1288	antiporter activity
C1A23_RS13230	COG0318	PFAM AMP-dependent synthetase and ligase
C1A23_RS13240	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C1A23_RS13240	COG0140	phosphoribosyl-ATP diphosphatase activity
C1A23_RS13245	COG0107	imidazoleglycerol-phosphate synthase activity
C1A23_RS13250	COG2198	Histidine kinase
C1A23_RS13250	COG0784	Response regulator, receiver
C1A23_RS13250	COG2205	protein histidine kinase activity
C1A23_RS13255	COG2199	diguanylate cyclase activity
C1A23_RS13260	COG3437	response regulator, receiver
C1A23_RS13265	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C1A23_RS13270	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C1A23_RS13275	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C1A23_RS13275	COG0131	Imidazoleglycerol-phosphate dehydratase
C1A23_RS13280	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C1A23_RS13285	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C1A23_RS13290	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C1A23_RS13300	COG1199	ATP-dependent helicase activity
C1A23_RS13310	COG1214	PFAM Peptidase M22, glycoprotease
C1A23_RS13320	COG0596	Alpha beta hydrolase
C1A23_RS13320	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
C1A23_RS13320	COG2226	methyltransferase
C1A23_RS13325	COG0318	PFAM AMP-dependent synthetase and ligase
C1A23_RS13330	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
C1A23_RS13345	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C1A23_RS13350	COG2832	Protein of unknown function (DUF454)
C1A23_RS13355	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C1A23_RS13365	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C1A23_RS13390	COG0517	IMP dehydrogenase activity
C1A23_RS13390	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C1A23_RS13390	COG0617	tRNA 3'-terminal CCA addition
C1A23_RS13395	COG1643	Atp-dependent helicase
C1A23_RS13405	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C1A23_RS13415	COG3437	response regulator, receiver
C1A23_RS13420	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C1A23_RS13425	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C1A23_RS13430	COG0709	Synthesizes selenophosphate from selenide and ATP
C1A23_RS13445	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1A23_RS13455	COG1254	Belongs to the acylphosphatase family
C1A23_RS13460	COG0625	glutathione transferase activity
C1A23_RS13465	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A23_RS13465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A23_RS13470	COG0489	protein tyrosine kinase activity
C1A23_RS13475	COG0572	uridine kinase
C1A23_RS13480	COG0717	Belongs to the dCTP deaminase family
C1A23_RS13490	COG0306	phosphate transporter
C1A23_RS13530	COG5001	Diguanylate cyclase
C1A23_RS13530	COG3300	MHYT domain
C1A23_RS13560	COG1484	DNA-dependent DNA replication
C1A23_RS13565	COG4584	PFAM Integrase catalytic
C1A23_RS13600	COG0110	maltose O-acetyltransferase activity
C1A23_RS13685	COG0697	spore germination
C1A23_RS13700	COG1530	ribonuclease E activity
C1A23_RS13705	COG0564	pseudouridine synthase activity
C1A23_RS13710	COG0546	phosphoglycolate phosphatase activity
C1A23_RS13715	COG0424	maF-like protein
C1A23_RS13720	COG2814	Major facilitator Superfamily
C1A23_RS13735	COG1399	metal-binding, possibly nucleic acid-binding protein
C1A23_RS13740	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C1A23_RS13745	COG0416	fatty acid biosynthetic process
C1A23_RS13750	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C1A23_RS13760	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS13765	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1A23_RS13775	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C1A23_RS13780	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C1A23_RS13785	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C1A23_RS13790	COG0470	DNA polymerase III
C1A23_RS13795	COG0084	hydrolase, TatD family'
C1A23_RS13810	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C1A23_RS13810	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1A23_RS13815	COG3008	intermembrane lipid transfer
C1A23_RS13820	COG2995	paraquat-inducible protein a
C1A23_RS13830	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C1A23_RS13835	COG0372	Belongs to the citrate synthase family
C1A23_RS13885	COG4221	oxidoreductase activity
C1A23_RS13895	COG3141	response to X-ray
C1A23_RS13945	COG1484	DNA-dependent DNA replication
C1A23_RS13950	COG4584	PFAM Integrase catalytic
C1A23_RS14000	COG1067	ATP-dependent peptidase activity
C1A23_RS14005	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C1A23_RS14020	COG0488	(ABC) transporter
C1A23_RS14030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C1A23_RS14030	COG0116	Belongs to the methyltransferase superfamily
C1A23_RS14040	COG0167	dihydroorotate dehydrogenase activity
C1A23_RS14045	COG2902	Dehydrogenase
C1A23_RS14055	COG0308	aminopeptidase N
C1A23_RS14065	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C1A23_RS14070	COG1956	GAF domain-containing protein
C1A23_RS14080	COG3278	Belongs to the heme-copper respiratory oxidase family
C1A23_RS14095	COG2010	Cytochrome c
C1A23_RS14120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C1A23_RS14125	COG0589	response to stress
C1A23_RS14130	COG0037	tRNA processing
C1A23_RS14150	COG1869	D-ribose catabolic process
C1A23_RS14155	COG1129	ABC transporter
C1A23_RS14160	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1A23_RS14165	COG1879	ABC-type sugar transport system periplasmic component
C1A23_RS14170	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1A23_RS14175	COG1609	Transcriptional regulator
C1A23_RS14180	COG5001	Diguanylate cyclase
C1A23_RS14180	COG3300	MHYT domain
C1A23_RS14210	COG0776	regulation of translation
C1A23_RS14215	COG0072	phenylalanine-tRNA ligase activity
C1A23_RS14215	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A23_RS14220	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C1A23_RS14225	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C1A23_RS14230	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C1A23_RS14235	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C1A23_RS14240	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C1A23_RS14260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1A23_RS14270	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1A23_RS14275	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C1A23_RS14280	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1A23_RS14285	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C1A23_RS14290	COG3313	Fe-S protein
C1A23_RS14295	COG2942	2-epimerase
C1A23_RS14300	COG3716	PTS system mannose fructose sorbose family IID component
C1A23_RS14305	COG3715	PTS system
C1A23_RS14310	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS14310	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS14325	COG1609	Transcriptional regulator
C1A23_RS14330	COG2140	Oxalate decarboxylase
C1A23_RS14340	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C1A23_RS14340	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1A23_RS14340	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C1A23_RS14345	COG1105	Belongs to the carbohydrate kinase PfkB family
C1A23_RS14350	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS14350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS14355	COG1609	Transcriptional regulator
C1A23_RS14360	COG0814	amino acid
C1A23_RS14370	COG5654	RES domain protein
C1A23_RS14375	COG0513	Belongs to the DEAD box helicase family
C1A23_RS14385	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C1A23_RS14390	COG2890	protein-(glutamine-N5) methyltransferase activity
C1A23_RS14395	COG2840	Smr protein MutS2
C1A23_RS14405	COG3706	GGDEF domain
C1A23_RS14435	COG2824	Alkylphosphonate utilization operon protein PhnA
C1A23_RS14450	COG0384	phenazine biosynthesis protein PhzF
C1A23_RS14480	COG0242	peptide deformylase activity
C1A23_RS14495	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1A23_RS14500	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C1A23_RS14505	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C1A23_RS14515	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C1A23_RS14520	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C1A23_RS14530	COG0205	6-phosphofructokinase activity
C1A23_RS14535	COG1473	amidohydrolase
C1A23_RS14540	COG1011	Hydrolase
C1A23_RS14545	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C1A23_RS14600	COG3593	DNA synthesis involved in DNA repair
C1A23_RS14615	COG0583	DNA-binding transcription factor activity
C1A23_RS14620	COG0730	response to heat
C1A23_RS14625	COG3148	PFAM DTW domain containing protein
C1A23_RS14635	COG1181	Belongs to the D-alanine--D-alanine ligase family
C1A23_RS14650	COG0386	Belongs to the glutathione peroxidase family
C1A23_RS14655	COG0513	Belongs to the DEAD box helicase family
C1A23_RS14670	COG1742	UPF0060 membrane protein
C1A23_RS14700	COG2329	Antibiotic biosynthesis monooxygenase
C1A23_RS14705	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C1A23_RS14725	COG3243	poly(R)-hydroxyalkanoic acid synthase
C1A23_RS14735	COG2501	S4 domain
C1A23_RS14750	COG1132	(ABC) transporter
C1A23_RS14760	COG1132	(ABC) transporter
C1A23_RS14770	COG3118	belongs to the thioredoxin family
C1A23_RS14775	COG0471	metal ion transport
C1A23_RS14780	COG0058	SHG alpha-glucan phosphorylase activity
C1A23_RS14815	COG0814	amino acid
C1A23_RS14820	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C1A23_RS14825	COG0514	ATP-dependent DNA helicase (RecQ)
C1A23_RS14830	COG2766	serine protein kinase
C1A23_RS14840	COG2719	SpoVR family
C1A23_RS14845	COG2186	Transcriptional regulator
C1A23_RS14850	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1A23_RS14855	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C1A23_RS14860	COG0586	Pfam SNARE associated Golgi protein
C1A23_RS14870	COG0556	nucleotide-excision repair
C1A23_RS14885	COG2985	domain, Protein
C1A23_RS14885	COG0569	domain protein
C1A23_RS14895	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C1A23_RS14915	COG4565	transcriptional regulatory protein
C1A23_RS14920	COG3290	protein histidine kinase activity
C1A23_RS14925	COG1940	carbohydrate kinase activity
C1A23_RS14925	COG1846	Transcriptional regulator
C1A23_RS14930	COG0840	transmembrane signaling receptor activity
C1A23_RS14935	COG3012	SEC-C Motif Domain Protein
C1A23_RS14940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C1A23_RS14945	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C1A23_RS14950	COG0247	lactate metabolic process
C1A23_RS14965	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C1A23_RS14970	COG0437	4 iron, 4 sulfur cluster binding
C1A23_RS14975	COG3301	Polysulphide reductase, NrfD
C1A23_RS14985	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C1A23_RS14990	COG4235	cytochrome complex assembly
C1A23_RS14990	COG3088	subunit of a heme lyase
C1A23_RS14995	COG1051	belongs to the nudix hydrolase family
C1A23_RS15005	COG3033	Beta-eliminating lyase
C1A23_RS15015	COG3046	protein related to deoxyribodipyrimidine photolyase
C1A23_RS15020	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1A23_RS15045	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C1A23_RS15050	COG0583	DNA-binding transcription factor activity
C1A23_RS15060	COG4774	siderophore transport
C1A23_RS15075	COG0583	DNA-binding transcription factor activity
C1A23_RS15080	COG2910	NAD(P)H-binding
C1A23_RS15095	COG0612	Peptidase, M16
C1A23_RS15100	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1A23_RS15110	COG1944	ATP diphosphatase activity
C1A23_RS15115	COG2116	formate transmembrane transporter activity
C1A23_RS15120	COG1882	Formate acetyltransferase
C1A23_RS15125	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A23_RS15130	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C1A23_RS15135	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C1A23_RS15145	COG1840	ABC-type Fe3 transport system, periplasmic component
C1A23_RS15150	COG3842	ATPase activity
C1A23_RS15160	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1A23_RS15165	COG2983	Belongs to the UPF0260 family
C1A23_RS15175	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C1A23_RS15180	COG0045	succinate-CoA ligase (ADP-forming) activity
C1A23_RS15185	COG0508	dehydrogenase complex catalyzes the overall conversion of
C1A23_RS15190	COG0567	Dehydrogenase, E1 component
C1A23_RS15200	COG1053	succinate dehydrogenase
C1A23_RS15205	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C1A23_RS15230	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1A23_RS15235	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C1A23_RS15235	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1A23_RS15245	COG3069	C4-dicarboxylate transmembrane transporter activity
C1A23_RS15260	COG1451	nucleotide metabolic process
C1A23_RS15275	COG0254	rRNA binding
C1A23_RS15280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C1A23_RS15290	COG0583	DNA-binding transcription factor activity
C1A23_RS15300	COG1172	Belongs to the binding-protein-dependent transport system permease family
C1A23_RS15310	COG1879	ABC-type sugar transport system periplasmic component
C1A23_RS15315	COG1069	ribulokinase activity
C1A23_RS15325	COG2160	L-arabinose isomerase activity
C1A23_RS15330	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C1A23_RS15340	COG2925	Exonuclease
C1A23_RS15350	COG3345	alpha-galactosidase
C1A23_RS15355	COG1380	Effector of murein hydrolase LrgA
C1A23_RS15360	COG1346	cytolysis
C1A23_RS15365	COG0295	cytidine deaminase activity
C1A23_RS15370	COG1022	Amp-dependent synthetase and ligase
C1A23_RS15385	COG0861	Integral membrane protein TerC family
C1A23_RS15390	COG2885	chlorophyll binding
C1A23_RS15395	COG2199	diguanylate cyclase activity
C1A23_RS15415	COG2154	pterin-4-alpha-carbinolamine dehydratase
C1A23_RS15425	COG3768	UPF0283 membrane protein
C1A23_RS15430	COG3106	COG3106 Predicted ATPase
C1A23_RS15445	COG1842	Phage shock protein A
C1A23_RS15450	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C1A23_RS15460	COG4168	peptide transport system, permease
C1A23_RS15465	COG4171	peptide transport system, permease
C1A23_RS15475	COG4172	Belongs to the ABC transporter superfamily
C1A23_RS15485	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C1A23_RS15490	COG1286	toxin biosynthetic process
C1A23_RS15495	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C1A23_RS15505	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C1A23_RS15510	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C1A23_RS15515	COG1674	ftsk spoiiie
C1A23_RS15515	COG0531	amino acid
C1A23_RS15525	COG0686	Belongs to the AlaDH PNT family
C1A23_RS15530	COG0492	ferredoxin-NADP+ reductase activity
C1A23_RS15535	COG3706	GGDEF domain
C1A23_RS15540	COG3134	Outer membrane lipoprotein
C1A23_RS15545	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C1A23_RS15550	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C1A23_RS15555	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C1A23_RS15560	COG0542	response to heat
C1A23_RS15565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C1A23_RS15570	COG1278	Cold shock
C1A23_RS15575	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C1A23_RS15595	COG4584	PFAM Integrase catalytic
C1A23_RS15600	COG1484	DNA-dependent DNA replication
C1A23_RS15645	COG3829	transcription factor binding
C1A23_RS15700	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C1A23_RS15720	COG3501	Rhs element vgr protein
C1A23_RS15740	COG0659	secondary active sulfate transmembrane transporter activity
C1A23_RS15770	COG0672	)-iron permease
C1A23_RS15790	COG2814	Major facilitator Superfamily
C1A23_RS15800	COG1136	(ABC) transporter
C1A23_RS15805	COG0577	efflux transmembrane transporter activity
C1A23_RS15845	COG1139	Iron-sulfur cluster binding protein
C1A23_RS15850	COG0247	lactate metabolic process
C1A23_RS15855	COG1620	l-lactate permease
C1A23_RS15860	COG0583	DNA-binding transcription factor activity
C1A23_RS15870	COG0346	lactoylglutathione lyase activity
C1A23_RS15875	COG0596	Alpha beta hydrolase
C1A23_RS15900	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C1A23_RS15905	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C1A23_RS15905	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1A23_RS15910	COG0527	aspartate kinase activity
C1A23_RS15920	COG1368	sulfuric ester hydrolase activity
C1A23_RS15925	COG1619	proteins homologs of microcin C7 resistance protein MccF
C1A23_RS15930	COG4667	esterase of the alpha-beta hydrolase superfamily
C1A23_RS15950	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C1A23_RS15950	COG1648	precorrin-2 dehydrogenase activity
C1A23_RS15960	COG0393	Putative heavy-metal-binding
C1A23_RS15980	COG1252	NADH dehydrogenase
C1A23_RS15985	COG3150	esterase
C1A23_RS15990	COG2233	PERMEase
C1A23_RS16010	COG2354	Protein conserved in bacteria
C1A23_RS16020	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1A23_RS16025	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C1A23_RS16060	COG0537	adenosine 5'-monophosphoramidase activity
C1A23_RS16075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C1A23_RS16090	COG1301	dicarboxylic acid transport
C1A23_RS16100	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C1A23_RS16105	COG0861	Integral membrane protein TerC family
C1A23_RS16120	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1A23_RS16125	COG0601	transmembrane transport
C1A23_RS16135	COG2095	MarC family integral membrane protein
C1A23_RS16145	COG1454	alcohol dehydrogenase
C1A23_RS16145	COG1012	belongs to the aldehyde dehydrogenase family
C1A23_RS16150	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C1A23_RS16150	COG2199	diguanylate cyclase activity
C1A23_RS16155	COG3275	phosphorelay sensor kinase activity
C1A23_RS16160	COG3279	Response regulator of the LytR AlgR family
C1A23_RS16165	COG1966	Carbon starvation protein
C1A23_RS16175	COG1566	PFAM secretion protein HlyD family protein
C1A23_RS16180	COG1061	Type III restriction enzyme res subunit
C1A23_RS16185	COG2027	D-alanyl-D-alanine carboxypeptidase
C1A23_RS16190	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C1A23_RS16200	COG0436	Aminotransferase
C1A23_RS16205	COG1288	antiporter activity
C1A23_RS16210	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C1A23_RS16230	COG0697	spore germination
C1A23_RS16235	COG4657	Part of a membrane complex involved in electron transport
C1A23_RS16240	COG2878	Part of a membrane complex involved in electron transport
C1A23_RS16250	COG4658	electron transport chain
C1A23_RS16255	COG4659	FMN binding
C1A23_RS16260	COG4660	Part of a membrane complex involved in electron transport
C1A23_RS16265	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C1A23_RS16270	COG0346	lactoylglutathione lyase activity
C1A23_RS16285	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C1A23_RS16290	COG2056	Na+-H+ antiporter family
C1A23_RS16300	COG2050	protein possibly involved in aromatic compounds catabolism
C1A23_RS16310	COG0247	lactate metabolic process
C1A23_RS16310	COG0277	FAD linked oxidase domain protein
C1A23_RS16320	COG1253	flavin adenine dinucleotide binding
C1A23_RS16325	COG1902	pentaerythritol trinitrate reductase activity
C1A23_RS16335	COG0647	UMP catabolic process
C1A23_RS16340	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1A23_RS16340	COG4651	solute:proton antiporter activity
C1A23_RS16350	COG0367	asparagine synthase
C1A23_RS16360	COG0625	glutathione transferase activity
C1A23_RS16365	COG0625	glutathione transferase activity
C1A23_RS16375	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C1A23_RS16390	COG0564	pseudouridine synthase activity
C1A23_RS16395	COG5001	Diguanylate cyclase
C1A23_RS16400	COG0840	transmembrane signaling receptor activity
C1A23_RS16410	COG0392	lysyltransferase activity
C1A23_RS16410	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
C1A23_RS16420	COG2194	sulfuric ester hydrolase activity
C1A23_RS16440	COG0670	Belongs to the BI1 family
C1A23_RS16445	COG1289	transmembrane transporter activity
C1A23_RS16450	COG2920	part of a sulfur-relay system
C1A23_RS16455	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C1A23_RS16460	COG0285	dihydrofolate synthase activity
C1A23_RS16465	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C1A23_RS16470	COG0101	tRNA pseudouridine synthase activity
C1A23_RS16480	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C1A23_RS16485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1A23_RS16490	COG0671	phosphoesterase, PA-phosphatase related
C1A23_RS16495	COG1464	Belongs to the NlpA lipoprotein family
C1A23_RS16535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C1A23_RS16535	COG0574	Belongs to the PEP-utilizing enzyme family
C1A23_RS16540	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C1A23_RS16610	COG1242	4 iron, 4 sulfur cluster binding
C1A23_RS16615	COG0067	glutamate synthase
C1A23_RS16615	COG0070	glutamate synthase
C1A23_RS16615	COG0069	glutamate synthase activity
C1A23_RS16620	COG0493	'glutamate synthase
C1A23_RS16625	COG1126	abc transporter atp-binding protein
C1A23_RS16630	COG0765	amino acid transport
C1A23_RS16665	COG0789	Transcriptional regulator
C1A23_RS16680	COG4104	PAAR repeat-containing protein
C1A23_RS16690	COG0513	Belongs to the DEAD box helicase family
C1A23_RS16695	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1A23_RS16725	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C1A23_RS16730	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C1A23_RS16735	COG0505	Belongs to the CarA family
C1A23_RS16740	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C1A23_RS16750	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C1A23_RS16755	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C1A23_RS16760	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C1A23_RS16765	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C1A23_RS16770	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1A23_RS16780	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
C1A23_RS16790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS16790	COG2205	protein histidine kinase activity
C1A23_RS16805	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C1A23_RS16830	COG0023	Translation Initiation Factor
C1A23_RS16835	COG2119	membrane
C1A23_RS16865	COG2199	diguanylate cyclase activity
C1A23_RS16865	COG2203	Gaf domain
C1A23_RS16880	COG1204	response to ionizing radiation
C1A23_RS16885	COG5433	transposase activity
C1A23_RS16895	COG0215	cysteine-tRNA ligase activity
C1A23_RS16900	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C1A23_RS16910	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C1A23_RS16915	COG3301	Polysulphide reductase, NrfD
C1A23_RS16920	COG0437	4 iron, 4 sulfur cluster binding
C1A23_RS16925	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C1A23_RS17000	COG2314	TM2 domain
C1A23_RS17020	COG0582	viral genome integration into host DNA
C1A23_RS17040	COG4584	PFAM Integrase catalytic
C1A23_RS17045	COG1484	DNA-dependent DNA replication
C1A23_RS17120	COG0322	excinuclease ABC activity
C1A23_RS17125	COG2197	response regulator
C1A23_RS17130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C1A23_RS17135	COG2835	tetraacyldisaccharide 4'-kinase activity
C1A23_RS17140	COG1663	tetraacyldisaccharide 4'-kinase activity
C1A23_RS17150	COG0658	competence protein
C1A23_RS17150	COG2333	competence protein COMEC
C1A23_RS17165	COG0433	COG0433 Predicted ATPase
C1A23_RS17170	COG1448	Aminotransferase
C1A23_RS17185	COG3385	transposase activity
C1A23_RS17195	COG1199	ATP-dependent helicase activity
C1A23_RS17205	COG0123	including yeast histone deacetylase and acetoin utilization protein
C1A23_RS17210	COG0477	Major facilitator Superfamily
C1A23_RS17220	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C1A23_RS17245	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1A23_RS17260	COG2271	Major facilitator Superfamily
C1A23_RS17270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS17275	COG0765	amino acid transport
C1A23_RS17280	COG1126	abc transporter atp-binding protein
C1A23_RS17300	COG0531	amino acid
C1A23_RS17315	COG1253	flavin adenine dinucleotide binding
C1A23_RS17320	COG0704	Plays a role in the regulation of phosphate uptake
C1A23_RS17325	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C1A23_RS17330	COG0581	inorganic phosphate transmembrane transporter activity
C1A23_RS17335	COG0573	inorganic phosphate transmembrane transporter activity
C1A23_RS17340	COG0590	tRNA wobble adenosine to inosine editing
C1A23_RS17350	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C1A23_RS17370	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C1A23_RS17375	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C1A23_RS17380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C1A23_RS17385	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C1A23_RS17410	COG2716	regulation of RNA biosynthetic process
C1A23_RS17415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C1A23_RS17425	COG2239	Acts as a magnesium transporter
C1A23_RS17435	COG1256	bacterial-type flagellum assembly
C1A23_RS17445	COG1706	bacterial-type flagellum-dependent cell motility
C1A23_RS17450	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C1A23_RS17460	COG4787	bacterial-type flagellum-dependent cell motility
C1A23_RS17480	COG1815	bacterial-type flagellum-dependent cell motility
C1A23_RS17485	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C1A23_RS17490	COG0835	chemotaxis
C1A23_RS17490	COG0784	Response regulator, receiver
C1A23_RS17495	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C1A23_RS17510	COG0622	Phosphoesterase
C1A23_RS17540	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1A23_RS17545	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1A23_RS17550	COG1882	Formate acetyltransferase
C1A23_RS17555	COG1349	DNA-binding transcription factor activity
C1A23_RS17590	COG1278	Cold shock
C1A23_RS17610	COG2988	succinylglutamate desuccinylase activity
C1A23_RS17630	COG3132	Protein of unknown function, DUF480
C1A23_RS17640	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C1A23_RS17665	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
C1A23_RS17720	COG0438	transferase activity, transferring glycosyl groups
C1A23_RS17735	COG1216	Glycosyl transferase, family 2
C1A23_RS17740	COG5039	Polysaccharide pyruvyl transferase
C1A23_RS17765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C1A23_RS17780	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C1A23_RS17815	COG1091	dTDP-4-dehydrorhamnose reductase activity
C1A23_RS17830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS17835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS17840	COG1309	transcriptional regulator
C1A23_RS17855	COG1946	Acyl-CoA thioesterase
C1A23_RS17865	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C1A23_RS17875	COG0009	L-threonylcarbamoyladenylate synthase
C1A23_RS17885	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C1A23_RS17890	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1A23_RS17890	COG0512	Glutamine amidotransferase of anthranilate synthase
C1A23_RS17895	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C1A23_RS17900	COG0134	indole-3-glycerol-phosphate synthase activity
C1A23_RS17900	COG0135	phosphoribosylanthranilate isomerase activity
C1A23_RS17905	COG0133	tryptophan synthase activity
C1A23_RS17910	COG0159	tryptophan synthase activity
C1A23_RS17970	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1A23_RS18000	COG3311	Transcriptional regulator
C1A23_RS18015	COG1335	isochorismatase
C1A23_RS18020	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C1A23_RS18025	COG1304	FMN binding
C1A23_RS18030	COG0549	Belongs to the carbamate kinase family
C1A23_RS18045	COG0583	DNA-binding transcription factor activity
C1A23_RS18085	COG2003	Belongs to the UPF0758 family
C1A23_RS18130	COG3381	protein complex oligomerization
C1A23_RS18140	COG3005	denitrification pathway
C1A23_RS18145	COG0745	RESPONSE REGULATOR receiver
C1A23_RS18155	COG1879	ABC-type sugar transport system periplasmic component
C1A23_RS18160	COG2205	protein histidine kinase activity
C1A23_RS18160	COG2198	Histidine kinase
C1A23_RS18160	COG0784	Response regulator, receiver
C1A23_RS18170	COG2814	Major facilitator Superfamily
C1A23_RS18175	COG0109	protoheme IX farnesyltransferase activity
C1A23_RS18180	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C1A23_RS18185	COG1845	cytochrome c oxidase, subunit III
C1A23_RS18190	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C1A23_RS18195	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C1A23_RS18240	COG2211	Major facilitator Superfamily
C1A23_RS18255	COG0708	Exodeoxyribonuclease III
C1A23_RS18275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS18280	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C1A23_RS18300	COG0095	Lipoate-protein ligase
C1A23_RS18320	COG2391	methyltransferase activity
C1A23_RS18330	COG0640	Transcriptional regulator
C1A23_RS18345	COG1285	pathogenesis
C1A23_RS18375	COG0484	heat shock protein binding
C1A23_RS18380	COG0443	Heat shock 70 kDa protein
C1A23_RS18385	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C1A23_RS18390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C1A23_RS18395	COG0497	DNA recombination
C1A23_RS18400	COG1227	inorganic diphosphatase activity
C1A23_RS18410	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS18415	COG0577	efflux transmembrane transporter activity
C1A23_RS18415	COG1136	(ABC) transporter
C1A23_RS18425	COG2375	cellular response to nickel ion
C1A23_RS18430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C1A23_RS18450	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C1A23_RS18455	COG1396	sequence-specific DNA binding
C1A23_RS18455	COG1917	Cupin 2, conserved barrel domain protein
C1A23_RS18470	COG0531	amino acid
C1A23_RS18480	COG0531	amino acid
C1A23_RS18490	COG1283	sodium-dependent phosphate transmembrane transporter activity
C1A23_RS18500	COG3384	dioxygenase
C1A23_RS18505	COG2205	protein histidine kinase activity
C1A23_RS18505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS18520	COG0813	purine-nucleoside phosphorylase activity
C1A23_RS18535	COG2801	Transposase and inactivated derivatives
C1A23_RS18545	COG4319	ketosteroid isomerase
C1A23_RS18550	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C1A23_RS18555	COG0083	homoserine kinase activity
C1A23_RS18570	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C1A23_RS18575	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
C1A23_RS18590	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C1A23_RS18600	COG0745	RESPONSE REGULATOR receiver
C1A23_RS18615	COG4988	ABC transporter
C1A23_RS18620	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C1A23_RS18640	COG1720	tRNA m6t6A37 methyltransferase activity
C1A23_RS18655	COG0542	response to heat
C1A23_RS18660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C1A23_RS18665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS18675	COG2190	(PTS) system
C1A23_RS18690	COG3038	cytochrome b561
C1A23_RS18700	COG0419	ATPase involved in DNA repair
C1A23_RS18705	COG0420	3'-5' exonuclease activity
C1A23_RS18715	COG2974	May be involved in recombination
C1A23_RS18725	COG4651	solute:proton antiporter activity
C1A23_RS18725	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C1A23_RS18740	COG0469	pyruvate kinase activity
C1A23_RS18745	COG3264	Mechanosensitive ion channel
C1A23_RS18745	COG1196	nuclear chromosome segregation
C1A23_RS18765	COG0281	malic enzyme
C1A23_RS18780	COG0437	4 iron, 4 sulfur cluster binding
C1A23_RS18785	COG3383	formate dehydrogenase (NAD+) activity
C1A23_RS18785	COG3383	formate dehydrogenase (NAD+) activity
C1A23_RS18815	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C1A23_RS18820	COG1910	domain protein
C1A23_RS18825	COG3852	Histidine kinase
C1A23_RS18830	COG2204	response regulator
C1A23_RS18840	COG4662	Binding-protein-dependent transport system inner membrane component
C1A23_RS18850	COG0746	molybdenum cofactor guanylyltransferase activity
C1A23_RS18855	COG0303	'Molybdopterin
C1A23_RS18860	COG1289	transmembrane transporter activity
C1A23_RS18890	COG3220	belongs to the UPF0276 family
C1A23_RS18920	COG0784	Response regulator, receiver
C1A23_RS18920	COG2205	protein histidine kinase activity
C1A23_RS18925	COG4166	transmembrane transport
C1A23_RS18930	COG0601	transmembrane transport
C1A23_RS18935	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C1A23_RS18940	COG0444	Belongs to the ABC transporter superfamily
C1A23_RS18945	COG4608	Belongs to the ABC transporter superfamily
C1A23_RS18955	COG2971	BadF BadG BcrA BcrD
C1A23_RS18965	COG0840	transmembrane signaling receptor activity
C1A23_RS18985	COG3724	N-succinylarginine dihydrolase activity
C1A23_RS18990	COG0616	signal peptide processing
C1A23_RS18995	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS19000	COG0583	DNA-binding transcription factor activity
C1A23_RS19010	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C1A23_RS19020	COG0583	DNA-binding transcription factor activity
C1A23_RS19025	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C1A23_RS19030	COG1881	PFAM PEBP family protein
C1A23_RS19040	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C1A23_RS19040	COG3408	Glycogen debranching enzyme
C1A23_RS19045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1A23_RS19050	COG0739	heme binding
C1A23_RS19055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C1A23_RS19080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C1A23_RS19090	COG3091	SprT-like family
C1A23_RS19100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C1A23_RS19105	COG0189	ligase activity
C1A23_RS19115	COG1678	Uncharacterized ACR, COG1678
C1A23_RS19120	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C1A23_RS19125	COG3104	oligopeptide transport
C1A23_RS19155	COG0714	Associated with various cellular activities
C1A23_RS19170	COG1115	amino acid carrier protein
C1A23_RS19175	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C1A23_RS19190	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C1A23_RS19200	COG1301	dicarboxylic acid transport
C1A23_RS19205	COG2877	3-deoxy-8-phosphooctulonate synthase activity
C1A23_RS19210	COG2912	Transglutaminase-like superfamily
C1A23_RS19220	COG2890	protein-(glutamine-N5) methyltransferase activity
C1A23_RS19225	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C1A23_RS19230	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C1A23_RS19235	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C1A23_RS19240	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C1A23_RS19250	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C1A23_RS19255	COG0737	Belongs to the 5'-nucleotidase family
C1A23_RS19260	COG0193	aminoacyl-tRNA hydrolase activity
C1A23_RS19265	COG0012	GTP binding
C1A23_RS19310	COG0490	domain, Protein
C1A23_RS19310	COG0471	metal ion transport
C1A23_RS19320	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C1A23_RS19340	COG0366	Alpha amylase catalytic
C1A23_RS19350	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C1A23_RS19350	COG1013	pyruvate-flavodoxin oxidoreductase activity
C1A23_RS19350	COG0674	pyruvate-flavodoxin oxidoreductase activity
C1A23_RS19350	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C1A23_RS19360	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A23_RS19370	COG1012	belongs to the aldehyde dehydrogenase family
C1A23_RS19380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C1A23_RS19395	COG0180	Tryptophanyl-tRNA synthetase
C1A23_RS19405	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C1A23_RS19415	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C1A23_RS19425	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C1A23_RS19430	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C1A23_RS19460	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C1A23_RS19465	COG0583	DNA-binding transcription factor activity
C1A23_RS19485	COG0583	DNA-binding transcription factor activity
C1A23_RS19500	COG0739	heme binding
C1A23_RS19510	COG3264	Mechanosensitive ion channel
C1A23_RS19510	COG1511	domain protein
C1A23_RS19515	COG0584	glycerophosphoryl diester phosphodiesterase
C1A23_RS19525	COG1053	succinate dehydrogenase
C1A23_RS19530	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C1A23_RS19535	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C1A23_RS19560	COG3214	Protein conserved in bacteria
C1A23_RS19600	COG0642	Histidine kinase
C1A23_RS19610	COG0516	GMP reductase activity
C1A23_RS19620	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C1A23_RS19625	COG3647	Membrane
C1A23_RS19635	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C1A23_RS19645	COG3706	GGDEF domain
C1A23_RS19655	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C1A23_RS19670	COG3706	GGDEF domain
C1A23_RS19680	COG1335	isochorismatase
C1A23_RS19685	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C1A23_RS19690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C1A23_RS19695	COG1702	phosphate starvation-inducible protein PhoH
C1A23_RS19700	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C1A23_RS19705	COG4535	Mg2 and Co2 transporter CorC
C1A23_RS19710	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C1A23_RS19715	COG2888	peptidyl-tyrosine sulfation
C1A23_RS19720	COG0495	leucyl-tRNA aminoacylation
C1A23_RS19740	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C1A23_RS19745	COG0799	negative regulation of ribosome biogenesis
C1A23_RS19750	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C1A23_RS19755	COG0768	penicillin binding
C1A23_RS19760	COG0772	Belongs to the SEDS family
C1A23_RS19765	COG2951	lytic endotransglycosylase activity
C1A23_RS19770	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C1A23_RS19775	COG1686	Belongs to the peptidase S11 family
C1A23_RS19780	COG2921	Belongs to the UPF0250 family
C1A23_RS19785	COG0321	lipoyl(octanoyl) transferase activity
C1A23_RS19795	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C1A23_RS19805	COG3545	Serine hydrolase
C1A23_RS19810	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C1A23_RS19825	COG0789	Transcriptional regulator
C1A23_RS19835	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C1A23_RS19840	COG1970	mechanosensitive ion channel activity
C1A23_RS19850	COG4974	Belongs to the 'phage' integrase family
C1A23_RS19860	COG0312	modulator of DNA gyrase
C1A23_RS19865	COG0312	modulator of DNA gyrase
C1A23_RS19930	COG3275	phosphorelay sensor kinase activity
C1A23_RS19935	COG3279	Response regulator of the LytR AlgR family
C1A23_RS19940	COG1966	Carbon starvation protein
C1A23_RS19950	COG0114	fumarate hydratase activity
C1A23_RS19960	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C1A23_RS19970	COG2211	Major facilitator Superfamily
C1A23_RS19975	COG1185	polyribonucleotide nucleotidyltransferase activity
C1A23_RS19980	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C1A23_RS19985	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C1A23_RS19990	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C1A23_RS19995	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C1A23_RS20000	COG0195	Participates in both transcription termination and antitermination
C1A23_RS20005	COG0779	Required for maturation of 30S ribosomal subunits
C1A23_RS20020	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C1A23_RS20025	COG0149	triose-phosphate isomerase activity
C1A23_RS20030	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C1A23_RS20035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C1A23_RS20045	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C1A23_RS20050	COG1534	Rna-binding protein
C1A23_RS20065	COG1360	Flagellar Motor Protein
C1A23_RS20070	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C1A23_RS20075	COG1722	exodeoxyribonuclease VII activity
C1A23_RS20080	COG0142	geranyltranstransferase activity
C1A23_RS20085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C1A23_RS20095	COG0601	transmembrane transport
C1A23_RS20105	COG4172	Belongs to the ABC transporter superfamily
C1A23_RS20110	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C1A23_RS20115	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C1A23_RS20120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1A23_RS20125	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C1A23_RS20145	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1A23_RS20145	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C1A23_RS20150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C1A23_RS20165	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C1A23_RS20175	COG3381	protein complex oligomerization
C1A23_RS20195	COG3300	MHYT domain
C1A23_RS20195	COG5001	Diguanylate cyclase
C1A23_RS20205	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1A23_RS20210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C1A23_RS20215	COG0511	ligase activity, forming carbon-carbon bonds
C1A23_RS20220	COG0439	Biotin carboxylase
C1A23_RS20230	COG4145	pantothenate transmembrane transporter activity
C1A23_RS20235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS20235	COG2190	(PTS) system
C1A23_RS20235	COG1263	PTS System
C1A23_RS20240	COG0583	DNA-binding transcription factor activity
C1A23_RS20245	COG0604	alcohol dehydrogenase
C1A23_RS20250	COG2264	protein methyltransferase activity
C1A23_RS20265	COG0778	Nitroreductase
C1A23_RS20270	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1A23_RS20270	COG1902	pentaerythritol trinitrate reductase activity
C1A23_RS20275	COG0616	signal peptide processing
C1A23_RS20295	COG3139	Protein of unknown function (DUF1315)
C1A23_RS20300	COG0252	asparaginase activity
C1A23_RS20305	COG0786	glutamate:sodium symporter activity
C1A23_RS20320	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C1A23_RS20325	COG0384	phenazine biosynthesis protein PhzF
C1A23_RS20330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1A23_RS20335	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1A23_RS20340	COG0175	sulfate reduction
C1A23_RS20345	COG2113	Glycine betaine
C1A23_RS20355	COG4175	Glycine betaine
C1A23_RS20365	COG3610	response to peptide
C1A23_RS20370	COG2966	Psort location CytoplasmicMembrane, score
C1A23_RS20390	COG0521	Mo-molybdopterin cofactor biosynthetic process
C1A23_RS20400	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1A23_RS20405	COG1028	Short-chain dehydrogenase reductase Sdr
C1A23_RS20415	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C1A23_RS20440	COG2986	histidine ammonia-lyase
C1A23_RS20465	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C1A23_RS20505	COG1858	cytochrome C peroxidase
C1A23_RS20520	COG2313	pseudouridylate synthase activity
C1A23_RS20525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1A23_RS20530	COG2146	nitrite reductase [NAD(P)H] activity
C1A23_RS20530	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1A23_RS20535	COG2146	nitrite reductase [NAD(P)H] activity
C1A23_RS20535	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C1A23_RS20540	COG1116	anion transmembrane transporter activity
C1A23_RS20545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C1A23_RS20550	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C1A23_RS20550	COG1116	anion transmembrane transporter activity
C1A23_RS20565	COG0243	molybdopterin cofactor binding
C1A23_RS20600	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C1A23_RS20615	COG1073	alpha beta
C1A23_RS20620	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C1A23_RS20635	COG2195	Cleaves the N-terminal amino acid of tripeptides
C1A23_RS20645	COG4608	Belongs to the ABC transporter superfamily
C1A23_RS20650	COG0444	Belongs to the ABC transporter superfamily
C1A23_RS20660	COG4239	(ABC) transporter, permease
C1A23_RS20665	COG4174	ABC transporter (Permease)
C1A23_RS20680	COG0811	peptide transport
C1A23_RS20685	COG0811	peptide transport
C1A23_RS20690	COG0848	biopolymer transport protein
C1A23_RS20745	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C1A23_RS20750	COG0840	transmembrane signaling receptor activity
C1A23_RS20760	COG1278	Cold shock
C1A23_RS20800	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C1A23_RS20805	COG1162	GTPase activity
C1A23_RS20810	COG0688	phosphatidylethanolamine metabolic process
C1A23_RS20815	COG4628	conserved protein (DUF2132)
C1A23_RS20830	COG3059	membrane
C1A23_RS20835	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C1A23_RS20840	COG2207	Transcriptional regulator
C1A23_RS20850	COG5001	Diguanylate cyclase
C1A23_RS20850	COG3300	MHYT domain
C1A23_RS20855	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C1A23_RS20875	COG3706	GGDEF domain
C1A23_RS20875	COG4251	negative regulation of phosphorylation
C1A23_RS20875	COG5001	Diguanylate cyclase
C1A23_RS20875	COG2203	Gaf domain
C1A23_RS20885	COG3039	Transposase
C1A23_RS20935	COG4974	Belongs to the 'phage' integrase family
C1A23_RS20945	COG4735	regulation of single-species biofilm formation
C1A23_RS20955	COG1484	DNA-dependent DNA replication
C1A23_RS20960	COG4584	PFAM Integrase catalytic
C1A23_RS20965	COG2314	TM2 domain
C1A23_RS20985	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1A23_RS20995	COG3621	Patatin-like phospholipase
C1A23_RS21010	COG0582	viral genome integration into host DNA
C1A23_RS21035	COG1132	(ABC) transporter
C1A23_RS21045	COG1404	Belongs to the peptidase S8 family
C1A23_RS21050	COG2897	thiosulfate sulfurtransferase activity
C1A23_RS21055	COG2066	Belongs to the glutaminase family
C1A23_RS21060	COG3171	Protein conserved in bacteria
C1A23_RS21065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C1A23_RS21070	COG4935	Belongs to the peptidase S8 family
C1A23_RS21070	COG2234	aminopeptidase activity
C1A23_RS21075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C1A23_RS21080	COG2200	EAL domain
C1A23_RS21085	COG1090	epimerase
C1A23_RS21090	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C1A23_RS21095	COG4181	ATPase activity
C1A23_RS21100	COG2755	lipolytic protein G-D-S-L family
C1A23_RS21105	COG0784	Response regulator, receiver
C1A23_RS21105	COG0835	chemotaxis
C1A23_RS21115	COG0569	domain protein
C1A23_RS21115	COG2985	domain, Protein
C1A23_RS21120	COG1272	protein, Hemolysin III
C1A23_RS21125	COG0076	glutamate decarboxylase activity
C1A23_RS21130	COG2917	probably involved in intracellular septation
C1A23_RS21135	COG2350	Protein conserved in bacteria
C1A23_RS21145	COG1555	photosystem II stabilization
C1A23_RS21150	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C1A23_RS21155	COG3104	oligopeptide transport
C1A23_RS21160	COG0745	RESPONSE REGULATOR receiver
C1A23_RS21190	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C1A23_RS21205	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C1A23_RS21230	COG0732	type I restriction modification DNA specificity domain
C1A23_RS21240	COG1484	DNA-dependent DNA replication
C1A23_RS21255	COG0840	transmembrane signaling receptor activity
C1A23_RS21285	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
C1A23_RS21310	COG0732	type I restriction modification DNA specificity domain
C1A23_RS21315	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
C1A23_RS21365	COG2003	Belongs to the UPF0758 family
C1A23_RS21415	COG5377	YqaJ viral recombinase family
C1A23_RS21430	COG4983	Phage plasmid primase, P4 family domain protein
C1A23_RS21450	COG1280	lysine exporter protein (LysE YggA)
C1A23_RS21480	COG2070	2-Nitropropane dioxygenase
C1A23_RS21505	COG1858	cytochrome C peroxidase
C1A23_RS21510	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C1A23_RS21530	COG0513	Belongs to the DEAD box helicase family
C1A23_RS21565	COG2957	Belongs to the agmatine deiminase family
C1A23_RS21580	COG1902	pentaerythritol trinitrate reductase activity
C1A23_RS21620	COG5001	Diguanylate cyclase
C1A23_RS21620	COG3300	MHYT domain
C1A23_RS21630	COG0714	Associated with various cellular activities
C1A23_RS21640	COG0456	acetyltransferase
C1A23_RS21650	COG1022	Amp-dependent synthetase and ligase
C1A23_RS21660	COG2918	glutathione biosynthetic process
C1A23_RS21665	COG0612	Peptidase, M16
C1A23_RS21670	COG1238	metal cluster binding
C1A23_RS21695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1A23_RS21700	COG0359	binds to the 23S rRNA
C1A23_RS21705	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C1A23_RS21710	COG0360	Binds together with S18 to 16S ribosomal RNA
C1A23_RS21715	COG1914	H( )-stimulated, divalent metal cation uptake system
C1A23_RS21720	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C1A23_RS21735	COG2153	protein acetylation
C1A23_RS21745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C1A23_RS21750	COG0557	exoribonuclease II activity
C1A23_RS21755	COG3706	GGDEF domain
C1A23_RS21760	COG1854	S-ribosylhomocysteine lyase activity
C1A23_RS21775	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C1A23_RS21775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1A23_RS21835	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C1A23_RS21840	COG1047	Peptidyl-prolyl cis-trans
C1A23_RS21845	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C1A23_RS21850	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C1A23_RS21855	COG0196	riboflavin kinase activity
C1A23_RS21860	COG0728	peptidoglycan biosynthetic process
C1A23_RS21865	COG0268	Binds directly to 16S ribosomal RNA
C1A23_RS21870	COG0640	Transcriptional regulator
C1A23_RS21875	COG0583	DNA-binding transcription factor activity
C1A23_RS21885	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C1A23_RS21890	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C1A23_RS21895	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C1A23_RS21905	COG1051	belongs to the nudix hydrolase family
C1A23_RS21915	COG3066	DNA modification
C1A23_RS21925	COG0335	large ribosomal subunit rRNA binding
C1A23_RS21930	COG0336	Belongs to the RNA methyltransferase TrmD family
C1A23_RS21935	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C1A23_RS21940	COG0228	four-way junction DNA binding
C1A23_RS21945	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C1A23_RS21950	COG4137	Cytochrome C assembly protein
C1A23_RS21955	COG4536	flavin adenine dinucleotide binding
C1A23_RS21965	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C1A23_RS21965	COG1017	nitric oxide dioxygenase activity
C1A23_RS21970	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C1A23_RS21975	COG0039	L-malate dehydrogenase activity
C1A23_RS21980	COG4160	amino acid transport
C1A23_RS21985	COG4215	(ABC) transporter
C1A23_RS21990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C1A23_RS21995	COG1126	abc transporter atp-binding protein
C1A23_RS22000	COG1438	arginine binding
C1A23_RS22005	COG2837	iron assimilation
C1A23_RS22010	COG3842	ATPase activity
C1A23_RS22020	COG1840	ABC-type Fe3 transport system, periplasmic component
C1A23_RS22025	COG0347	Belongs to the P(II) protein family
C1A23_RS22040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1A23_RS22045	COG0583	DNA-binding transcription factor activity
C1A23_RS22060	COG1929	Belongs to the glycerate kinase type-1 family
C1A23_RS22065	COG2610	gluconate transmembrane transporter activity
C1A23_RS22070	COG3835	regulator
C1A23_RS22075	COG3112	Uncharacterised protein family (UPF0231)
C1A23_RS22090	COG0840	transmembrane signaling receptor activity
C1A23_RS22110	COG0513	Belongs to the DEAD box helicase family
C1A23_RS22150	COG1448	Aminotransferase
C1A23_RS22165	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C1A23_RS22170	COG1328	CTP reductase activity
C1A23_RS22190	COG4946	Tricorn protease homolog
C1A23_RS22190	COG0793	Belongs to the peptidase S41A family
C1A23_RS22225	COG0840	transmembrane signaling receptor activity
C1A23_RS22230	COG3397	chitin binding
C1A23_RS22235	COG0583	DNA-binding transcription factor activity
C1A23_RS22240	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C1A23_RS22245	COG4208	sulfate ABC transporter
C1A23_RS22250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C1A23_RS22260	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C1A23_RS22265	COG3174	membrane
C1A23_RS22270	COG0110	maltose O-acetyltransferase activity
C1A23_RS22290	COG0165	Argininosuccinate lyase
C1A23_RS22295	COG0137	argininosuccinate synthase activity
C1A23_RS22305	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C1A23_RS22310	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C1A23_RS22320	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C1A23_RS22335	COG0527	aspartate kinase activity
C1A23_RS22335	COG0460	homoserine dehydrogenase
C1A23_RS22340	COG0626	cystathionine gamma-synthase activity
C1A23_RS22350	COG3708	Transcriptional regulator
C1A23_RS22350	COG2207	Transcriptional regulator
C1A23_RS22355	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A23_RS22360	COG0814	amino acid
C1A23_RS22365	COG1218	3'(2'),5'-bisphosphate nucleotidase
C1A23_RS22370	COG0494	nUDIX hydrolase
C1A23_RS22375	COG1011	Hydrolase
C1A23_RS22380	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C1A23_RS22395	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C1A23_RS22405	COG3156	type II secretion system protein K
C1A23_RS22420	COG4795	General secretion pathway protein
C1A23_RS22425	COG2165	general secretion pathway protein
C1A23_RS22440	COG2165	general secretion pathway protein
C1A23_RS22445	COG1459	type II secretion system
C1A23_RS22450	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1A23_RS22460	COG3031	protein transport across the cell outer membrane
C1A23_RS22470	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C1A23_RS22475	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C1A23_RS22500	COG3133	Outer membrane lipoprotein
C1A23_RS22515	COG2771	luxR family
C1A23_RS22520	COG3916	Acyl-homoserine-lactone synthase
C1A23_RS22530	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C1A23_RS22535	COG1309	transcriptional regulator
C1A23_RS22545	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C1A23_RS22545	COG2213	PTS system mannitol-specific
C1A23_RS22550	COG0246	Mannitol dehydrogenase
C1A23_RS22555	COG3722	fumarate hydratase activity
C1A23_RS22560	COG3263	regulation of cellular component size
C1A23_RS22585	COG1671	Belongs to the UPF0178 family
C1A23_RS22600	COG1988	membrane-bound metal-dependent
C1A23_RS22605	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C1A23_RS22610	COG0513	Belongs to the DEAD box helicase family
C1A23_RS22635	COG1575	Belongs to the MenA family. Type 1 subfamily
C1A23_RS22640	COG1169	isochorismate synthase
C1A23_RS22645	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C1A23_RS22650	COG0596	Alpha beta hydrolase
C1A23_RS22655	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C1A23_RS22660	COG1441	menaquinone biosynthetic process
C1A23_RS22665	COG0318	PFAM AMP-dependent synthetase and ligase
C1A23_RS22680	COG3539	Fimbrial protein
C1A23_RS22685	COG3121	Chaperone
C1A23_RS22690	COG3188	usher protein
C1A23_RS22700	COG3539	Fimbrial protein
C1A23_RS22705	COG3039	Transposase
C1A23_RS22720	COG3291	Pkd domain containing protein
C1A23_RS22725	COG2949	membrane
C1A23_RS22730	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C1A23_RS22745	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C1A23_RS22750	COG5380	lipid catabolic process
C1A23_RS22765	COG4533	DNA binding
C1A23_RS22775	COG2873	o-acetylhomoserine
C1A23_RS22785	COG1979	alcohol dehydrogenase
C1A23_RS22805	COG4221	oxidoreductase activity
C1A23_RS22825	COG1285	pathogenesis
C1A23_RS22845	COG1368	sulfuric ester hydrolase activity
C1A23_RS22850	COG1522	sequence-specific DNA binding
C1A23_RS22860	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C1A23_RS22865	COG1418	mRNA catabolic process
C1A23_RS22870	COG1058	Belongs to the CinA family
C1A23_RS22870	COG1546	Belongs to the CinA family
C1A23_RS22885	COG1129	ABC transporter
C1A23_RS22885	COG0842	Transport permease protein
C1A23_RS22900	COG0561	phosphatase activity
C1A23_RS22905	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C1A23_RS22925	COG1011	Hydrolase
C1A23_RS22940	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C1A23_RS22945	COG0019	diaminopimelate decarboxylase activity
C1A23_RS22955	COG1965	Belongs to the frataxin family
C1A23_RS22960	COG0400	carboxylic ester hydrolase activity
C1A23_RS22965	COG3072	Adenylate cyclase
C1A23_RS22970	COG0181	hydroxymethylbilane synthase activity
C1A23_RS22980	COG2959	enzyme of heme biosynthesis
C1A23_RS22995	COG1494	fructose-1,6-bisphosphatase
C1A23_RS23045	COG1733	regulation of RNA biosynthetic process
C1A23_RS23065	COG3932	Exopolysaccharide synthesis, ExoD
C1A23_RS23070	COG0814	amino acid
C1A23_RS23075	COG3706	GGDEF domain
C1A23_RS23090	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C1A23_RS23095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C1A23_RS23100	COG5433	transposase activity
C1A23_RS23110	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C1A23_RS23115	COG2022	thiamine diphosphate biosynthetic process
C1A23_RS23125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C1A23_RS23130	COG0352	thiamine-phosphate diphosphorylase activity
C1A23_RS23135	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C1A23_RS23160	COG0745	RESPONSE REGULATOR receiver
C1A23_RS23165	COG0642	Histidine kinase
C1A23_RS23175	COG0189	ligase activity
C1A23_RS23200	COG1639	'signal transduction protein
C1A23_RS23210	COG2321	neutral zinc metallopeptidase
C1A23_RS23215	COG3700	Belongs to the class B bacterial acid phosphatase family
C1A23_RS23235	COG1366	Belongs to the anti-sigma-factor antagonist family
C1A23_RS23240	COG2172	sigma factor antagonist activity
C1A23_RS23245	COG5002	protein histidine kinase activity
C1A23_RS23245	COG2205	protein histidine kinase activity
C1A23_RS23245	COG0784	Response regulator, receiver
C1A23_RS23250	COG3437	response regulator, receiver
C1A23_RS23260	COG0477	Major facilitator Superfamily
C1A23_RS23280	COG5433	transposase activity
C1A23_RS23290	COG1263	PTS System
C1A23_RS23290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C1A23_RS23300	COG5433	transposase activity
C1A23_RS23320	COG0312	modulator of DNA gyrase
C1A23_RS23325	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C1A23_RS23335	COG3164	Protein of unknown function
C1A23_RS23340	COG1530	ribonuclease E activity
C1A23_RS23345	COG0424	maF-like protein
C1A23_RS23350	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C1A23_RS23355	COG1792	Involved in formation and maintenance of cell shape
C1A23_RS23360	COG1077	Cell shape determining protein MreB Mrl
C1A23_RS23390	COG2165	general secretion pathway protein
C1A23_RS23395	COG2165	general secretion pathway protein
C1A23_RS23405	COG1459	type II secretion system
C1A23_RS23410	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C1A23_RS23455	COG2199	diguanylate cyclase activity
C1A23_RS23455	COG2200	EAL domain
C1A23_RS23460	COG2200	EAL domain
C1A23_RS23470	COG2986	histidine ammonia-lyase
C1A23_RS23475	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C1A23_RS23480	COG0010	Belongs to the arginase family
C1A23_RS23485	COG1228	amidohydrolase
C1A23_RS23490	COG2188	Transcriptional regulator
C1A23_RS23495	COG0288	reversible hydration of carbon dioxide
C1A23_RS23510	COG2177	Part of the ABC transporter FtsEX involved in
C1A23_RS23515	COG2884	Cell division ATP-binding protein ftsE
C1A23_RS23520	COG0552	protein localization to endoplasmic reticulum
C1A23_RS23525	COG0742	ribosomal rna small subunit methyltransferase
C1A23_RS23555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1A23_RS23560	COG0741	lytic transglycosylase activity
C1A23_RS23570	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1A23_RS23580	COG2095	MarC family integral membrane protein
C1A23_RS23590	COG1301	dicarboxylic acid transport
C1A23_RS23615	COG3714	YhhN family
C1A23_RS23640	COG1770	oligopeptidase
C1A23_RS23655	COG4221	oxidoreductase activity
C1A23_RS23660	COG0583	DNA-binding transcription factor activity
C1A23_RS23665	COG2249	NAD(P)H dehydrogenase (quinone) activity
C1A23_RS23685	COG4584	PFAM Integrase catalytic
C1A23_RS23690	COG1484	DNA-dependent DNA replication
C1A23_RS23735	COG0203	ribosomal protein L17
C1A23_RS23740	COG0202	RNA polymerase activity
C1A23_RS23745	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C1A23_RS23750	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C1A23_RS23755	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C1A23_RS23760	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C1A23_RS23765	COG0201	protein transport
C1A23_RS23770	COG0200	Binds to the 23S rRNA
C1A23_RS23775	COG1841	ribosomal large subunit assembly
C1A23_RS23780	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C1A23_RS23785	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C1A23_RS23790	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C1A23_RS23795	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C1A23_RS23800	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C1A23_RS23805	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C1A23_RS23810	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C1A23_RS23815	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C1A23_RS23820	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C1A23_RS23825	COG0255	Belongs to the universal ribosomal protein uL29 family
C1A23_RS23830	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C1A23_RS23835	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C1A23_RS23840	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C1A23_RS23845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C1A23_RS23850	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C1A23_RS23855	COG0089	rRNA binding
C1A23_RS23860	COG0088	Forms part of the polypeptide exit tunnel
C1A23_RS23865	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C1A23_RS23870	COG0051	transcription antitermination factor activity, RNA binding
C1A23_RS23890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C1A23_RS23895	COG2183	response to ionizing radiation
C1A23_RS23915	COG0596	Alpha beta hydrolase
C1A23_RS23920	COG1040	competence protein
C1A23_RS23925	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C1A23_RS23925	COG0316	Belongs to the HesB IscA family
C1A23_RS23930	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C1A23_RS23935	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C1A23_RS23940	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1A23_RS23945	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C1A23_RS23950	COG4942	peptidase
C1A23_RS23960	COG1609	Transcriptional regulator
C1A23_RS23965	COG0800	Aldolase
C1A23_RS23970	COG0129	dihydroxy-acid dehydratase activity
C1A23_RS23975	COG3265	gluconokinase activity
C1A23_RS23980	COG2610	gluconate transmembrane transporter activity
C1A23_RS23985	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C1A23_RS23990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C1A23_RS24000	COG0456	acetyltransferase
C1A23_RS24010	COG1490	D-aminoacyl-tRNA deacylase activity
C1A23_RS24015	COG1295	ribonuclease BN
C1A23_RS24020	COG1295	ribonuclease BN
C1A23_RS24025	COG1217	gtp-binding protein TYPA
C1A23_RS24030	COG0174	glutamine synthetase
C1A23_RS24040	COG3852	Histidine kinase
C1A23_RS24045	COG2204	response regulator
C1A23_RS24050	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C1A23_RS24055	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C1A23_RS24065	COG3078	GTPase activator activity
C1A23_RS24080	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C1A23_RS24090	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C1A23_RS24095	COG0408	coproporphyrinogen oxidase activity
C1A23_RS24100	COG0009	L-threonylcarbamoyladenylate synthase
C1A23_RS24110	COG0551	DNA topoisomerase type I activity
C1A23_RS24115	COG2922	Belongs to the Smg family
C1A23_RS24120	COG0758	DNA mediated transformation
C1A23_RS24130	COG0242	peptide deformylase activity
C1A23_RS24135	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C1A23_RS24140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C1A23_RS24140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C1A23_RS24145	COG0569	domain protein
C1A23_RS24150	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1A23_RS24155	COG1322	Protein conserved in bacteria
C1A23_RS24175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C1A23_RS24180	COG0686	Belongs to the AlaDH PNT family
C1A23_RS24185	COG0519	Catalyzes the synthesis of GMP from XMP
C1A23_RS24185	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C1A23_RS24195	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C1A23_RS24200	COG1396	sequence-specific DNA binding
C1A23_RS24205	COG1012	belongs to the aldehyde dehydrogenase family
C1A23_RS24215	COG2962	Rard protein
C1A23_RS24225	COG1280	lysine exporter protein (LysE YggA)
C1A23_RS24240	COG2391	methyltransferase activity
C1A23_RS24245	COG1280	lysine exporter protein (LysE YggA)
C1A23_RS24295	COG1943	Transposase
C1A23_RS24310	COG0210	DNA helicase
C1A23_RS24325	COG1744	ABC transporter substrate-binding protein PnrA-like
C1A23_RS24330	COG3845	ABC transporter
C1A23_RS24335	COG4603	Belongs to the binding-protein-dependent transport system permease family
C1A23_RS24340	COG1079	Belongs to the binding-protein-dependent transport system permease family
C1A23_RS24345	COG0583	DNA-binding transcription factor activity
C1A23_RS24365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C1A23_RS24370	COG0385	Bile acid
C1A23_RS24375	COG0531	amino acid
C1A23_RS24380	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C1A23_RS24385	COG0531	amino acid
C1A23_RS24390	COG2731	YhcH YjgK YiaL family protein
C1A23_RS24395	COG3250	beta-galactosidase activity
C1A23_RS24400	COG4584	PFAM Integrase catalytic
C1A23_RS24405	COG1484	DNA-dependent DNA replication
C1A23_RS24410	COG1609	Transcriptional regulator
C1A23_RS24450	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C1A23_RS24455	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1A23_RS24455	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C1A23_RS24465	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C1A23_RS24470	COG3074	FtsZ-dependent cytokinesis
C1A23_RS24480	COG1045	serine acetyltransferase
C1A23_RS24490	COG0745	RESPONSE REGULATOR receiver
C1A23_RS24495	COG2205	protein histidine kinase activity
C1A23_RS24500	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C1A23_RS24505	COG0534	Mate efflux family protein
C1A23_RS24530	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C1A23_RS24535	COG2937	Belongs to the GPAT DAPAT family
C1A23_RS24540	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C1A23_RS24545	COG3161	chorismate lyase activity
C1A23_RS24550	COG1580	Controls the rotational direction of flagella during chemotaxis
C1A23_RS24570	COG0604	alcohol dehydrogenase
C1A23_RS24575	COG1609	Transcriptional regulator
C1A23_RS24595	COG1519	Transferase
C1A23_RS24600	COG0859	PFAM glycosyl transferase family 9
C1A23_RS24605	COG0463	Glycosyl transferase, family 2
C1A23_RS24610	COG0859	PFAM glycosyl transferase family 9
C1A23_RS24615	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C1A23_RS24620	COG2990	Protein conserved in bacteria
C1A23_RS24625	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C1A23_RS24635	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C1A23_RS24640	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C1A23_RS24645	COG2003	Belongs to the UPF0758 family
C1A23_RS24650	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C1A23_RS24655	COG0756	dUTP diphosphatase activity
C1A23_RS24660	COG1309	transcriptional regulator
C1A23_RS24665	COG0668	transmembrane transport
C1A23_RS24680	COG0166	Belongs to the GPI family
C1A23_RS24685	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C1A23_RS24690	COG0583	DNA-binding transcription factor activity
C1A23_RS24730	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C1A23_RS24735	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C1A23_RS24740	COG1739	Uncharacterized protein family UPF0029
C1A23_RS24745	COG0006	proline dipeptidase activity
C1A23_RS24750	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C1A23_RS24755	COG1250	3-hydroxyacyl-CoA dehydrogenase
C1A23_RS24755	COG1024	Enoyl-CoA hydratase
C1A23_RS24760	COG0183	Belongs to the thiolase family
C1A23_RS24785	COG0425	Belongs to the sulfur carrier protein TusA family
C1A23_RS24790	COG0251	oxidation-reduction process
C1A23_RS24800	COG2885	chlorophyll binding
C1A23_RS24805	COG1335	isochorismatase
C1A23_RS24810	COG2818	Glycosylase
C1A23_RS24815	COG0752	glycyl-tRNA synthetase alpha subunit
C1A23_RS24820	COG0751	glycine-tRNA ligase activity
C1A23_RS24830	COG0529	Catalyzes the synthesis of activated sulfate
C1A23_RS24830	COG2046	Belongs to the sulfate adenylyltransferase family
C1A23_RS24845	COG0814	amino acid
C1A23_RS24850	COG0348	domain, Protein
C1A23_RS24860	COG0446	pyridine nucleotide-disulphide oxidoreductase
C1A23_RS24865	COG0426	domain, Protein
C1A23_RS24865	COG1773	rubredoxin
C1A23_RS24870	COG3604	Transcriptional regulator
C1A23_RS24875	COG2188	Transcriptional regulator
C1A23_RS24890	COG1609	Transcriptional regulator
C1A23_RS24930	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C1A23_RS24955	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C1A23_RS24970	COG3118	belongs to the thioredoxin family
C1A23_RS24975	COG0513	Belongs to the DEAD box helicase family
C1A23_RS24980	COG0248	Ppx GppA phosphatase
C1A23_RS24995	COG0742	ribosomal rna small subunit methyltransferase
C1A23_RS25015	COG0084	hydrolase, TatD family'
C1A23_RS25020	COG0805	protein transport
C1A23_RS25025	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C1A23_RS25035	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C1A23_RS25040	COG3165	ubiquinone biosynthetic process from chorismate
C1A23_RS25050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C1A23_RS25055	COG0402	S-adenosylhomocysteine deaminase activity
C1A23_RS25100	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C1A23_RS25105	COG0848	biopolymer transport protein
C1A23_RS25110	COG0811	peptide transport
C1A23_RS25115	COG0811	peptide transport
C1A23_RS25125	COG2771	luxR family
C1A23_RS25130	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C1A23_RS25135	COG1349	DNA-binding transcription factor activity
C1A23_RS25140	COG0745	RESPONSE REGULATOR receiver
C1A23_RS25145	COG2205	protein histidine kinase activity
C1A23_RS25160	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C1A23_RS25165	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C1A23_RS25170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C1A23_RS25175	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C1A23_RS25180	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C1A23_RS25185	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C1A23_RS25190	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C1A23_RS25200	COG0356	it plays a direct role in the translocation of protons across the membrane
C1A23_RS25210	COG1475	DNA binding
C1A23_RS25215	COG1192	Involved in chromosome partitioning
C1A23_RS25220	COG0357	Ribosomal RNA small subunit methyltransferase G
C1A23_RS25225	COG0445	tRNA wobble uridine modification
C1A23_RS25230	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C1A23_RS25235	COG4774	siderophore transport
C1A23_RS25240	COG4615	Cyclic peptide transporter
C1A23_RS25245	COG1120	ATPase activity
C1A23_RS25260	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C1A23_RS25265	COG0706	membrane insertase activity
C1A23_RS25270	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C1A23_RS25275	COG0594	ribonuclease P activity
C1A23_RS25280	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C1A23_RS25285	COG1126	abc transporter atp-binding protein