locus-tag	class	description
HWC28_gp070	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HWC28_gp107	COG0338	D12 class N6 adenine-specific DNA methyltransferase
HWC28_gp129	COG0863	Belongs to the N(4) N(6)-methyltransferase family
HWC28_gp186	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HWC28_gp193	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HWC28_gp193	COG1328	CTP reductase activity
HWC28_gp194	COG0602	queuosine metabolic process
HWC28_gp197	COG3179	chitinase
HWC28_gp199	COG1702	phosphate starvation-inducible protein PhoH
HWC28_gp205	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery