locus-tag	class	description
HWB28_gp018	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HWB28_gp019	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HWB28_gp020	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HWB28_gp021	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
HWB28_gp033	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HWB28_gp040	ENOG4105CQ2	DNA polymerase
HWB28_gp050	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HWB28_gp078	ENOG4105KSC	Transcriptional regulator, TraR DksA family
HWB28_gp094	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HWB28_gp118	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HWB28_gp133	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HWB28_gp307	ENOG4105DF5	DNA topoisomerase IV, subunit A
HWB28_gp327	ENOG4107104	thymidine kinase
HWB28_gp345	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)