locus-tag	class	description
HOT04_gp003	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HOT04_gp028	ENOG4108R1E	Serine threonine protein phosphatase 1
HOT04_gp050	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HOT04_gp053	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HOT04_gp055	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HOT04_gp057	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HOT04_gp062	ENOG4105C2M	dna polymerase I
HOT04_gp069	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HOT04_gp082	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
HOT04_gp103	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
HOT04_gp104	ENOG4107XDY	Nicotinamide Mononucleotide Transporter
HOT04_gp116	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)