locus-tag	class	description
C7N77_RS00060	COG2985	domain, Protein
C7N77_RS00060	COG0569	domain protein
C7N77_RS00065	COG1272	protein, Hemolysin III
C7N77_RS00070	COG0076	glutamate decarboxylase activity
C7N77_RS00075	COG2917	probably involved in intracellular septation
C7N77_RS00080	COG2350	Protein conserved in bacteria
C7N77_RS00090	COG1555	photosystem II stabilization
C7N77_RS00095	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C7N77_RS00100	COG3104	oligopeptide transport
C7N77_RS00105	COG0745	RESPONSE REGULATOR receiver
C7N77_RS00135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N77_RS00145	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7N77_RS00150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C7N77_RS00215	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C7N77_RS00250	COG3706	GGDEF domain
C7N77_RS00255	COG0513	Belongs to the DEAD box helicase family
C7N77_RS00275	COG2957	Belongs to the agmatine deiminase family
C7N77_RS00285	COG2852	Protein conserved in bacteria
C7N77_RS00300	COG1902	pentaerythritol trinitrate reductase activity
C7N77_RS00310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7N77_RS00315	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C7N77_RS00330	COG2425	protein containing a von Willebrand factor type A (vWA) domain
C7N77_RS00345	COG0456	acetyltransferase
C7N77_RS00355	COG1022	Amp-dependent synthetase and ligase
C7N77_RS00365	COG1794	racemase activity, acting on amino acids and derivatives
C7N77_RS00380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7N77_RS00390	COG0733	neurotransmitter:sodium symporter activity
C7N77_RS00395	COG0733	neurotransmitter:sodium symporter activity
C7N77_RS00410	COG0561	phosphatase activity
C7N77_RS00440	COG1846	Transcriptional regulator
C7N77_RS00445	COG2130	NADP-dependent
C7N77_RS00470	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C7N77_RS00475	COG1640	4-alpha-glucanotransferase
C7N77_RS00480	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7N77_RS00490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C7N77_RS00565	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C7N77_RS00570	COG2885	chlorophyll binding
C7N77_RS00575	COG0823	Involved in the tonB-independent uptake of proteins
C7N77_RS00590	COG0811	peptide transport
C7N77_RS00595	COG0824	Thioesterase
C7N77_RS00600	COG3790	cyd operon protein YbgE
C7N77_RS00605	COG4890	Cyd operon protein YbgT
C7N77_RS00610	COG1294	oxidase, subunit
C7N77_RS00615	COG1271	oxidase subunit
C7N77_RS00620	COG2255	four-way junction helicase activity
C7N77_RS00625	COG0632	four-way junction helicase activity
C7N77_RS00630	COG0840	transmembrane signaling receptor activity
C7N77_RS00635	COG0442	prolyl-tRNA aminoacylation
C7N77_RS00640	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N77_RS00640	COG1199	ATP-dependent helicase activity
C7N77_RS00645	COG4221	oxidoreductase activity
C7N77_RS00660	COG1024	Enoyl-CoA hydratase
C7N77_RS00670	COG0110	maltose O-acetyltransferase activity
C7N77_RS00680	COG4166	transmembrane transport
C7N77_RS00700	COG0513	Belongs to the DEAD box helicase family
C7N77_RS00735	COG0457	Tetratricopeptide repeat
C7N77_RS00735	COG3118	belongs to the thioredoxin family
C7N77_RS00745	COG1215	transferase activity, transferring glycosyl groups
C7N77_RS00755	COG1192	Involved in chromosome partitioning
C7N77_RS00765	COG2194	sulfuric ester hydrolase activity
C7N77_RS00770	COG1448	Aminotransferase
C7N77_RS00785	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7N77_RS00790	COG1328	CTP reductase activity
C7N77_RS00815	COG0840	transmembrane signaling receptor activity
C7N77_RS00820	COG3397	chitin binding
C7N77_RS00825	COG0583	DNA-binding transcription factor activity
C7N77_RS00830	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C7N77_RS00835	COG4208	sulfate ABC transporter
C7N77_RS00840	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C7N77_RS00850	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7N77_RS00880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C7N77_RS00885	COG0564	pseudouridine synthase activity
C7N77_RS00905	COG0459	protein refolding
C7N77_RS00910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C7N77_RS00915	COG0534	Mate efflux family protein
C7N77_RS00920	COG3030	protein affecting phage T7 exclusion by the F plasmid
C7N77_RS00925	COG1027	Aspartate ammonia-lyase
C7N77_RS00930	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7N77_RS00940	COG0612	Peptidase, M16
C7N77_RS00945	COG1238	metal cluster binding
C7N77_RS00980	COG0359	binds to the 23S rRNA
C7N77_RS00985	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C7N77_RS00990	COG0360	Binds together with S18 to 16S ribosomal RNA
C7N77_RS00995	COG1914	H( )-stimulated, divalent metal cation uptake system
C7N77_RS01010	COG2153	protein acetylation
C7N77_RS01020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7N77_RS01025	COG0557	exoribonuclease II activity
C7N77_RS01030	COG3706	GGDEF domain
C7N77_RS01035	COG1854	S-ribosylhomocysteine lyase activity
C7N77_RS01050	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C7N77_RS01050	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7N77_RS01090	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C7N77_RS01095	COG1047	Peptidyl-prolyl cis-trans
C7N77_RS01100	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C7N77_RS01110	COG0196	riboflavin kinase activity
C7N77_RS01115	COG0728	peptidoglycan biosynthetic process
C7N77_RS01120	COG0268	Binds directly to 16S ribosomal RNA
C7N77_RS01125	COG0640	Transcriptional regulator
C7N77_RS01130	COG0583	DNA-binding transcription factor activity
C7N77_RS01140	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7N77_RS01145	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C7N77_RS01150	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C7N77_RS01160	COG1051	belongs to the nudix hydrolase family
C7N77_RS01175	COG0335	large ribosomal subunit rRNA binding
C7N77_RS01180	COG0336	Belongs to the RNA methyltransferase TrmD family
C7N77_RS01185	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C7N77_RS01190	COG0228	four-way junction DNA binding
C7N77_RS01195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C7N77_RS01200	COG4137	Cytochrome C assembly protein
C7N77_RS01205	COG4536	flavin adenine dinucleotide binding
C7N77_RS01215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N77_RS01215	COG1017	nitric oxide dioxygenase activity
C7N77_RS01220	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C7N77_RS01225	COG0039	L-malate dehydrogenase activity
C7N77_RS01230	COG4160	amino acid transport
C7N77_RS01235	COG4215	(ABC) transporter
C7N77_RS01240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS01245	COG1126	abc transporter atp-binding protein
C7N77_RS01250	COG1438	arginine binding
C7N77_RS01255	COG2837	iron assimilation
C7N77_RS01260	COG3842	ATPase activity
C7N77_RS01280	COG0347	Belongs to the P(II) protein family
C7N77_RS01295	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7N77_RS01300	COG0583	DNA-binding transcription factor activity
C7N77_RS01315	COG1929	Belongs to the glycerate kinase type-1 family
C7N77_RS01320	COG2610	gluconate transmembrane transporter activity
C7N77_RS01325	COG3835	regulator
C7N77_RS01335	COG3112	Uncharacterised protein family (UPF0231)
C7N77_RS01355	COG1872	DUF167
C7N77_RS01360	COG0762	integral membrane protein
C7N77_RS01365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C7N77_RS01370	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C7N77_RS01385	COG3022	response to hydroperoxide
C7N77_RS01390	COG0513	Belongs to the DEAD box helicase family
C7N77_RS01395	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C7N77_RS01415	COG0735	belongs to the Fur family
C7N77_RS01420	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7N77_RS01435	COG0776	regulation of translation
C7N77_RS01440	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C7N77_RS01450	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
C7N77_RS01470	COG0560	Phosphoserine phosphatase
C7N77_RS01480	COG3064	Membrane
C7N77_RS01490	COG0813	purine-nucleoside phosphorylase activity
C7N77_RS01495	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C7N77_RS01500	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C7N77_RS01505	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C7N77_RS01515	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7N77_RS01520	COG0084	hydrolase, TatD family'
C7N77_RS01525	COG2165	general secretion pathway protein
C7N77_RS01535	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7N77_RS01540	COG0004	ammonium transporteR
C7N77_RS01560	COG0795	lipopolysaccharide-transporting ATPase activity
C7N77_RS01565	COG0795	lipopolysaccharide-transporting ATPase activity
C7N77_RS01570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7N77_RS01575	COG2927	DNA polymerase III (CHI subunit)
C7N77_RS01585	COG1253	flavin adenine dinucleotide binding
C7N77_RS01590	COG0586	Pfam SNARE associated Golgi protein
C7N77_RS01595	COG1686	Belongs to the peptidase S11 family
C7N77_RS01630	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C7N77_RS01635	COG0527	aspartate kinase activity
C7N77_RS01640	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C7N77_RS01645	COG2137	regulation of response to DNA damage stimulus
C7N77_RS01650	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C7N77_RS01655	COG1546	Belongs to the CinA family
C7N77_RS01665	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C7N77_RS01695	COG0739	heme binding
C7N77_RS01715	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C7N77_RS01720	COG1121	(ABC) transporter
C7N77_RS01725	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C7N77_RS01730	COG0583	DNA-binding transcription factor activity
C7N77_RS01740	COG1573	uracil-dna glycosylase
C7N77_RS01750	COG2827	Endonuclease containing a URI domain
C7N77_RS01765	COG1842	Phage shock protein A
C7N77_RS01770	COG0204	Acyl-transferase
C7N77_RS01790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7N77_RS01835	COG0456	acetyltransferase
C7N77_RS01860	COG1289	transmembrane transporter activity
C7N77_RS01865	COG1566	PFAM secretion protein HlyD family protein
C7N77_RS01880	COG1051	belongs to the nudix hydrolase family
C7N77_RS01885	COG3150	esterase
C7N77_RS01895	COG3151	Protein conserved in bacteria
C7N77_RS01900	COG0494	nUDIX hydrolase
C7N77_RS01905	COG1538	Outer membrane efflux protein
C7N77_RS01910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C7N77_RS01910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C7N77_RS01915	COG1560	Kdo2-lipid A biosynthetic process
C7N77_RS01930	COG2771	luxR family
C7N77_RS01945	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C7N77_RS01955	COG0246	Mannitol dehydrogenase
C7N77_RS01960	COG3722	fumarate hydratase activity
C7N77_RS01985	COG1671	Belongs to the UPF0178 family
C7N77_RS01990	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C7N77_RS01995	COG0513	Belongs to the DEAD box helicase family
C7N77_RS02020	COG0523	cobalamin synthesis protein
C7N77_RS02025	COG2879	small protein
C7N77_RS02030	COG1966	Carbon starvation protein
C7N77_RS02035	COG1575	Belongs to the MenA family. Type 1 subfamily
C7N77_RS02040	COG1169	isochorismate synthase
C7N77_RS02050	COG0596	Alpha beta hydrolase
C7N77_RS02055	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C7N77_RS02060	COG1441	menaquinone biosynthetic process
C7N77_RS02065	COG0318	PFAM AMP-dependent synthetase and ligase
C7N77_RS02070	COG2949	membrane
C7N77_RS02075	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C7N77_RS02085	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C7N77_RS02090	COG5380	lipid catabolic process
C7N77_RS02115	COG2873	o-acetylhomoserine
C7N77_RS02125	COG1979	alcohol dehydrogenase
C7N77_RS02140	COG4221	oxidoreductase activity
C7N77_RS02160	COG1285	pathogenesis
C7N77_RS02175	COG1368	sulfuric ester hydrolase activity
C7N77_RS02180	COG1522	sequence-specific DNA binding
C7N77_RS02190	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C7N77_RS02200	COG1058	Belongs to the CinA family
C7N77_RS02200	COG1546	Belongs to the CinA family
C7N77_RS02205	COG1988	membrane-bound metal-dependent
C7N77_RS02215	COG0561	phosphatase activity
C7N77_RS02220	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C7N77_RS02240	COG1011	Hydrolase
C7N77_RS02255	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C7N77_RS02260	COG0019	diaminopimelate decarboxylase activity
C7N77_RS02270	COG1965	Belongs to the frataxin family
C7N77_RS02275	COG0400	carboxylic ester hydrolase activity
C7N77_RS02280	COG3072	Adenylate cyclase
C7N77_RS02285	COG0181	hydroxymethylbilane synthase activity
C7N77_RS02295	COG2959	enzyme of heme biosynthesis
C7N77_RS02300	COG3071	HemY protein
C7N77_RS02310	COG1494	fructose-1,6-bisphosphatase
C7N77_RS02350	COG3932	Exopolysaccharide synthesis, ExoD
C7N77_RS02380	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7N77_RS02385	COG2022	thiamine diphosphate biosynthetic process
C7N77_RS02395	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7N77_RS02400	COG0352	thiamine-phosphate diphosphorylase activity
C7N77_RS02405	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C7N77_RS02425	COG0745	RESPONSE REGULATOR receiver
C7N77_RS02435	COG0189	ligase activity
C7N77_RS02470	COG2321	neutral zinc metallopeptidase
C7N77_RS02480	COG0477	Major facilitator Superfamily
C7N77_RS02495	COG0312	modulator of DNA gyrase
C7N77_RS02500	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7N77_RS02505	COG3164	Protein of unknown function
C7N77_RS02510	COG1530	ribonuclease E activity
C7N77_RS02515	COG0424	maF-like protein
C7N77_RS02520	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C7N77_RS02525	COG1792	Involved in formation and maintenance of cell shape
C7N77_RS02530	COG1077	Cell shape determining protein MreB Mrl
C7N77_RS02560	COG2165	general secretion pathway protein
C7N77_RS02575	COG1459	type II secretion system
C7N77_RS02580	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7N77_RS02630	COG2200	EAL domain
C7N77_RS02635	COG0387	Pfam Sodium calcium exchanger
C7N77_RS02640	COG2986	histidine ammonia-lyase
C7N77_RS02645	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C7N77_RS02650	COG0010	Belongs to the arginase family
C7N77_RS02655	COG1228	amidohydrolase
C7N77_RS02660	COG2188	Transcriptional regulator
C7N77_RS02665	COG0288	reversible hydration of carbon dioxide
C7N77_RS02675	COG2177	Part of the ABC transporter FtsEX involved in
C7N77_RS02680	COG2884	Cell division ATP-binding protein ftsE
C7N77_RS02685	COG0552	protein localization to endoplasmic reticulum
C7N77_RS02690	COG0742	ribosomal rna small subunit methyltransferase
C7N77_RS02725	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7N77_RS02730	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C7N77_RS02740	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7N77_RS02750	COG2095	MarC family integral membrane protein
C7N77_RS02760	COG1301	dicarboxylic acid transport
C7N77_RS02785	COG3714	YhhN family
C7N77_RS02805	COG1770	oligopeptidase
C7N77_RS02820	COG4221	oxidoreductase activity
C7N77_RS02825	COG0583	DNA-binding transcription factor activity
C7N77_RS02885	COG0203	ribosomal protein L17
C7N77_RS02890	COG0202	RNA polymerase activity
C7N77_RS02895	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C7N77_RS02900	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C7N77_RS02905	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C7N77_RS02910	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7N77_RS02915	COG0201	protein transport
C7N77_RS02920	COG0200	Binds to the 23S rRNA
C7N77_RS02925	COG1841	ribosomal large subunit assembly
C7N77_RS02930	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C7N77_RS02935	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C7N77_RS02940	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C7N77_RS02945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C7N77_RS02950	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C7N77_RS02955	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C7N77_RS02960	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C7N77_RS02965	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C7N77_RS02970	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C7N77_RS02975	COG0255	Belongs to the universal ribosomal protein uL29 family
C7N77_RS02980	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C7N77_RS02985	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C7N77_RS02990	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C7N77_RS02995	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C7N77_RS03000	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C7N77_RS03005	COG0089	rRNA binding
C7N77_RS03010	COG0088	Forms part of the polypeptide exit tunnel
C7N77_RS03015	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C7N77_RS03020	COG0051	transcription antitermination factor activity, RNA binding
C7N77_RS03030	COG2205	protein histidine kinase activity
C7N77_RS03040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7N77_RS03060	COG0596	Alpha beta hydrolase
C7N77_RS03065	COG1040	competence protein
C7N77_RS03070	COG0316	Belongs to the HesB IscA family
C7N77_RS03070	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C7N77_RS03075	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C7N77_RS03080	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C7N77_RS03085	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7N77_RS03090	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C7N77_RS03095	COG4942	peptidase
C7N77_RS03105	COG1609	Transcriptional regulator
C7N77_RS03120	COG0800	Aldolase
C7N77_RS03125	COG0129	dihydroxy-acid dehydratase activity
C7N77_RS03130	COG3265	gluconokinase activity
C7N77_RS03135	COG2610	gluconate transmembrane transporter activity
C7N77_RS03140	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C7N77_RS03145	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C7N77_RS03155	COG0456	acetyltransferase
C7N77_RS03165	COG1490	D-aminoacyl-tRNA deacylase activity
C7N77_RS03170	COG1295	ribonuclease BN
C7N77_RS03175	COG1295	ribonuclease BN
C7N77_RS03180	COG1217	gtp-binding protein TYPA
C7N77_RS03185	COG0174	glutamine synthetase
C7N77_RS03195	COG3852	Histidine kinase
C7N77_RS03205	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C7N77_RS03210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7N77_RS03220	COG3078	GTPase activator activity
C7N77_RS03230	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C7N77_RS03235	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C7N77_RS03240	COG0408	coproporphyrinogen oxidase activity
C7N77_RS03245	COG0009	L-threonylcarbamoyladenylate synthase
C7N77_RS03250	COG0551	DNA topoisomerase type I activity
C7N77_RS03255	COG2922	Belongs to the Smg family
C7N77_RS03260	COG0758	DNA mediated transformation
C7N77_RS03270	COG0242	peptide deformylase activity
C7N77_RS03275	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C7N77_RS03280	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7N77_RS03280	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7N77_RS03290	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7N77_RS03295	COG1322	Protein conserved in bacteria
C7N77_RS03315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N77_RS03325	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7N77_RS03325	COG0519	Catalyzes the synthesis of GMP from XMP
C7N77_RS03335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C7N77_RS03345	COG1012	belongs to the aldehyde dehydrogenase family
C7N77_RS03355	COG2962	Rard protein
C7N77_RS03365	COG1280	lysine exporter protein (LysE YggA)
C7N77_RS03375	COG1280	lysine exporter protein (LysE YggA)
C7N77_RS03380	COG0583	DNA-binding transcription factor activity
C7N77_RS03425	COG2823	Periplasmic or secreted lipoprotein
C7N77_RS03440	COG0583	DNA-binding transcription factor activity
C7N77_RS03445	COG1943	Transposase
C7N77_RS03450	COG0210	DNA helicase
C7N77_RS03465	COG1744	ABC transporter substrate-binding protein PnrA-like
C7N77_RS03470	COG3845	ABC transporter
C7N77_RS03475	COG4603	Belongs to the binding-protein-dependent transport system permease family
C7N77_RS03480	COG1079	Belongs to the binding-protein-dependent transport system permease family
C7N77_RS03485	COG0583	DNA-binding transcription factor activity
C7N77_RS03515	COG0385	Bile acid
C7N77_RS03520	COG0531	amino acid
C7N77_RS03525	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7N77_RS03530	COG0531	amino acid
C7N77_RS03535	COG2731	YhcH YjgK YiaL family protein
C7N77_RS03540	COG3250	beta-galactosidase activity
C7N77_RS03545	COG1609	Transcriptional regulator
C7N77_RS03580	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C7N77_RS03585	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7N77_RS03585	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7N77_RS03590	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C7N77_RS03595	COG3074	FtsZ-dependent cytokinesis
C7N77_RS03605	COG1045	serine acetyltransferase
C7N77_RS03615	COG0745	RESPONSE REGULATOR receiver
C7N77_RS03620	COG2205	protein histidine kinase activity
C7N77_RS03625	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C7N77_RS03630	COG0534	Mate efflux family protein
C7N77_RS03645	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C7N77_RS03650	COG2937	Belongs to the GPAT DAPAT family
C7N77_RS03655	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C7N77_RS03680	COG0604	alcohol dehydrogenase
C7N77_RS03720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7N77_RS03735	COG1063	alcohol dehydrogenase
C7N77_RS03745	COG3300	MHYT domain
C7N77_RS03745	COG5001	Diguanylate cyclase
C7N77_RS03750	COG0210	DNA helicase
C7N77_RS03755	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C7N77_RS03760	COG2166	iron-sulfur cluster assembly
C7N77_RS03765	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C7N77_RS03810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C7N77_RS03815	COG4206	TonB-dependent receptor
C7N77_RS03820	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C7N77_RS03825	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C7N77_RS03830	COG2223	nitrite transmembrane transporter activity
C7N77_RS03835	COG3279	Response regulator of the LytR AlgR family
C7N77_RS03840	COG3275	phosphorelay sensor kinase activity
C7N77_RS03850	COG2223	nitrite transmembrane transporter activity
C7N77_RS03855	COG2081	HI0933 family
C7N77_RS03860	COG1528	Iron-storage protein
C7N77_RS03865	COG3706	GGDEF domain
C7N77_RS03870	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7N77_RS03875	COG0589	response to stress
C7N77_RS03915	COG3642	lipopolysaccharide core region biosynthetic process
C7N77_RS03920	COG0859	PFAM glycosyl transferase family 9
C7N77_RS03935	COG1758	RNA polymerase activity
C7N77_RS03940	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7N77_RS03950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C7N77_RS03960	COG2267	carboxylic ester hydrolase activity
C7N77_RS03965	COG0561	phosphatase activity
C7N77_RS04000	COG1309	transcriptional regulator
C7N77_RS04005	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N77_RS04010	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N77_RS04015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS04015	COG4191	Histidine kinase
C7N77_RS04020	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7N77_RS04045	COG2205	protein histidine kinase activity
C7N77_RS04050	COG0745	RESPONSE REGULATOR receiver
C7N77_RS04055	COG2814	Major facilitator Superfamily
C7N77_RS04070	COG3977	Valine--pyruvate aminotransferase
C7N77_RS04075	COG0071	Belongs to the small heat shock protein (HSP20) family
C7N77_RS04080	COG0071	Belongs to the small heat shock protein (HSP20) family
C7N77_RS04085	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
C7N77_RS04095	COG0187	DNA topoisomerase II activity
C7N77_RS04105	COG0592	DNA-directed DNA polymerase activity
C7N77_RS04110	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C7N77_RS04125	COG1126	abc transporter atp-binding protein
C7N77_RS04130	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C7N77_RS04135	COG0594	ribonuclease P activity
C7N77_RS04140	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C7N77_RS04145	COG0706	membrane insertase activity
C7N77_RS04150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C7N77_RS04160	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7N77_RS04165	COG1120	ATPase activity
C7N77_RS04170	COG4615	Cyclic peptide transporter
C7N77_RS04175	COG4774	siderophore transport
C7N77_RS04180	COG0716	FMN binding
C7N77_RS04185	COG0445	tRNA wobble uridine modification
C7N77_RS04190	COG0357	Ribosomal RNA small subunit methyltransferase G
C7N77_RS04195	COG1192	Involved in chromosome partitioning
C7N77_RS04200	COG1475	DNA binding
C7N77_RS04210	COG0356	it plays a direct role in the translocation of protons across the membrane
C7N77_RS04220	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C7N77_RS04225	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C7N77_RS04230	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C7N77_RS04235	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C7N77_RS04240	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C7N77_RS04245	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C7N77_RS04250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C7N77_RS04255	COG4452	Inner membrane protein CreD
C7N77_RS04265	COG2205	protein histidine kinase activity
C7N77_RS04270	COG0745	RESPONSE REGULATOR receiver
C7N77_RS04275	COG1349	DNA-binding transcription factor activity
C7N77_RS04285	COG2771	luxR family
C7N77_RS04295	COG0811	peptide transport
C7N77_RS04300	COG0811	peptide transport
C7N77_RS04305	COG0848	biopolymer transport protein
C7N77_RS04310	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C7N77_RS04355	COG0402	S-adenosylhomocysteine deaminase activity
C7N77_RS04360	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C7N77_RS04365	COG2226	methyltransferase
C7N77_RS04370	COG3165	ubiquinone biosynthetic process from chorismate
C7N77_RS04375	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C7N77_RS04380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7N77_RS04385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C7N77_RS04390	COG0805	protein transport
C7N77_RS04395	COG0084	hydrolase, TatD family'
C7N77_RS04415	COG0742	ribosomal rna small subunit methyltransferase
C7N77_RS04425	COG0248	Ppx GppA phosphatase
C7N77_RS04430	COG0513	Belongs to the DEAD box helicase family
C7N77_RS04435	COG3118	belongs to the thioredoxin family
C7N77_RS04450	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C7N77_RS04460	COG2960	long-chain fatty acid transporting porin activity
C7N77_RS04475	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7N77_RS04515	COG1609	Transcriptional regulator
C7N77_RS04520	COG3604	Transcriptional regulator
C7N77_RS04525	COG1773	rubredoxin
C7N77_RS04525	COG0426	domain, Protein
C7N77_RS04530	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7N77_RS04550	COG3033	Beta-eliminating lyase
C7N77_RS04555	COG0814	amino acid
C7N77_RS04560	COG0814	amino acid
C7N77_RS04570	COG0640	Transcriptional regulator
C7N77_RS04590	COG0751	glycine-tRNA ligase activity
C7N77_RS04595	COG0752	glycyl-tRNA synthetase alpha subunit
C7N77_RS04600	COG2818	Glycosylase
C7N77_RS04605	COG1335	isochorismatase
C7N77_RS04625	COG2885	chlorophyll binding
C7N77_RS04630	COG0251	oxidation-reduction process
C7N77_RS04635	COG0425	Belongs to the sulfur carrier protein TusA family
C7N77_RS04665	COG0183	Belongs to the thiolase family
C7N77_RS04670	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7N77_RS04670	COG1024	Enoyl-CoA hydratase
C7N77_RS04675	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7N77_RS04680	COG0006	proline dipeptidase activity
C7N77_RS04685	COG1739	Uncharacterized protein family UPF0029
C7N77_RS04690	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7N77_RS04695	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C7N77_RS04720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N77_RS04720	COG1042	CoA-binding domain protein
C7N77_RS04720	COG0045	succinate-CoA ligase (ADP-forming) activity
C7N77_RS04730	COG0583	DNA-binding transcription factor activity
C7N77_RS04735	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C7N77_RS04740	COG0166	Belongs to the GPI family
C7N77_RS04745	COG0668	transmembrane transport
C7N77_RS04760	COG1309	transcriptional regulator
C7N77_RS04765	COG0756	dUTP diphosphatase activity
C7N77_RS04770	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C7N77_RS04775	COG2003	Belongs to the UPF0758 family
C7N77_RS04780	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C7N77_RS04785	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C7N77_RS04795	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C7N77_RS04800	COG2990	Protein conserved in bacteria
C7N77_RS04805	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C7N77_RS04810	COG0859	PFAM glycosyl transferase family 9
C7N77_RS04815	COG0463	Glycosyl transferase, family 2
C7N77_RS04820	COG0859	PFAM glycosyl transferase family 9
C7N77_RS04825	COG1519	Transferase
C7N77_RS04835	COG1561	YicC-like family, N-terminal region
C7N77_RS04840	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
C7N77_RS04845	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C7N77_RS04855	COG0789	Transcriptional regulator
C7N77_RS04860	COG3706	GGDEF domain
C7N77_RS04860	COG4251	negative regulation of phosphorylation
C7N77_RS04860	COG5001	Diguanylate cyclase
C7N77_RS04860	COG2203	Gaf domain
C7N77_RS04865	COG3084	Protein conserved in bacteria
C7N77_RS04875	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C7N77_RS04880	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C7N77_RS04890	COG1335	isochorismatase
C7N77_RS04900	COG1683	Conserved Protein
C7N77_RS04905	COG0204	Acyl-transferase
C7N77_RS04910	COG0204	Acyl-transferase
C7N77_RS04915	COG0606	chelatase, subunit chli
C7N77_RS04930	COG3978	acetolactate synthase activity
C7N77_RS04940	COG0129	dihydroxy-acid dehydratase activity
C7N77_RS04955	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C7N77_RS04960	COG0254	rRNA binding
C7N77_RS04965	COG0702	epimerase
C7N77_RS04970	COG0281	malic enzyme
C7N77_RS04980	COG2205	protein histidine kinase activity
C7N77_RS04985	COG0745	RESPONSE REGULATOR receiver
C7N77_RS04990	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7N77_RS05005	COG0366	Alpha amylase catalytic
C7N77_RS05020	COG0443	Heat shock 70 kDa protein
C7N77_RS05025	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7N77_RS05030	COG3045	CreA protein
C7N77_RS05050	COG0174	glutamine synthetase
C7N77_RS05070	COG3842	ATPase activity
C7N77_RS05075	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7N77_RS05080	COG1177	transmembrane transport
C7N77_RS05085	COG2258	MOSC domain
C7N77_RS05100	COG2050	protein possibly involved in aromatic compounds catabolism
C7N77_RS05105	COG0514	ATP-dependent DNA helicase (RecQ)
C7N77_RS05115	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C7N77_RS05125	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C7N77_RS05130	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C7N77_RS05135	COG2239	Acts as a magnesium transporter
C7N77_RS05140	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7N77_RS05140	COG1648	precorrin-2 dehydrogenase activity
C7N77_RS05145	COG2116	formate transmembrane transporter activity
C7N77_RS05155	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7N77_RS05160	COG0842	Transport permease protein
C7N77_RS05165	COG0842	Transport permease protein
C7N77_RS05170	COG1131	(ABC) transporter
C7N77_RS05175	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N77_RS05190	COG0477	Major facilitator Superfamily
C7N77_RS05195	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C7N77_RS05200	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C7N77_RS05220	COG1595	DNA-templated transcription, initiation
C7N77_RS05225	COG3806	Anti-sigma factor
C7N77_RS05230	COG1968	undecaprenyl-diphosphatase activity
C7N77_RS05235	COG0667	Aldo Keto reductase
C7N77_RS05240	COG2017	converts alpha-aldose to the beta-anomer
C7N77_RS05245	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C7N77_RS05255	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7N77_RS05260	COG1609	Transcriptional regulator
C7N77_RS05265	COG3250	beta-galactosidase activity
C7N77_RS05280	COG4211	Belongs to the binding-protein-dependent transport system permease family
C7N77_RS05305	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C7N77_RS05310	COG1288	antiporter activity
C7N77_RS05315	COG1438	arginine binding
C7N77_RS05320	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C7N77_RS05325	COG0540	Belongs to the ATCase OTCase family
C7N77_RS05350	COG3040	lipid binding
C7N77_RS05355	COG2207	Transcriptional regulator
C7N77_RS05360	COG1979	alcohol dehydrogenase
C7N77_RS05365	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C7N77_RS05370	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C7N77_RS05375	COG3681	Belongs to the UPF0597 family
C7N77_RS05385	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7N77_RS05390	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N77_RS05395	COG0564	pseudouridine synthase activity
C7N77_RS05405	COG0542	response to heat
C7N77_RS05415	COG2863	cytochrome
C7N77_RS05420	COG3258	Cytochrome c
C7N77_RS05425	COG2502	aspartate--ammonia ligase
C7N77_RS05430	COG1522	sequence-specific DNA binding
C7N77_RS05440	COG5413	integral membrane protein
C7N77_RS05445	COG0517	IMP dehydrogenase activity
C7N77_RS05445	COG0516	GMP reductase activity
C7N77_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS05465	COG2205	protein histidine kinase activity
C7N77_RS05475	COG2204	response regulator
C7N77_RS05490	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C7N77_RS05495	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C7N77_RS05525	COG0243	molybdopterin cofactor binding
C7N77_RS05530	COG3005	denitrification pathway
C7N77_RS05535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C7N77_RS05540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C7N77_RS05545	COG0569	domain protein
C7N77_RS05550	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C7N77_RS05575	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7N77_RS05590	COG0250	Participates in transcription elongation, termination and antitermination
C7N77_RS05595	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C7N77_RS05600	COG0081	regulation of translation
C7N77_RS05605	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C7N77_RS05610	COG0222	ribosome binding
C7N77_RS05615	COG0085	RNA polymerase activity
C7N77_RS05620	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C7N77_RS05625	COG2964	Protein conserved in bacteria
C7N77_RS05640	COG2923	Belongs to the DsrF TusC family
C7N77_RS05645	COG2168	tRNA wobble position uridine thiolation
C7N77_RS05650	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C7N77_RS05655	COG0049	tRNA binding
C7N77_RS05660	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C7N77_RS05665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C7N77_RS05670	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C7N77_RS05705	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
C7N77_RS05710	COG2252	PERMEase
C7N77_RS05715	COG2376	Dihydroxyacetone kinase
C7N77_RS05720	COG1461	Dihydroxyacetone kinase
C7N77_RS05725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS05725	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C7N77_RS05725	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7N77_RS05730	COG3284	Transcriptional regulator
C7N77_RS05735	COG0583	DNA-binding transcription factor activity
C7N77_RS05740	COG2957	Belongs to the agmatine deiminase family
C7N77_RS05750	COG2957	Belongs to the agmatine deiminase family
C7N77_RS05760	COG0628	permease
C7N77_RS05765	COG0671	phosphoesterase, PA-phosphatase related
C7N77_RS05785	COG0753	catalase activity
C7N77_RS05790	COG1247	-acetyltransferase
C7N77_RS05795	COG2207	Transcriptional regulator
C7N77_RS05825	COG3842	ATPase activity
C7N77_RS05860	COG0583	DNA-binding transcription factor activity
C7N77_RS05870	COG1741	Belongs to the pirin family
C7N77_RS05875	COG2259	Doxx family
C7N77_RS05880	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C7N77_RS05890	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C7N77_RS05895	COG0346	lactoylglutathione lyase activity
C7N77_RS05905	COG0004	ammonium transporteR
C7N77_RS05910	COG0347	Belongs to the P(II) protein family
C7N77_RS05915	COG3706	GGDEF domain
C7N77_RS05945	COG4771	TonB-dependent receptor
C7N77_RS05950	COG1278	Cold shock
C7N77_RS05970	COG0629	single-stranded DNA binding
C7N77_RS05975	COG2197	response regulator
C7N77_RS05980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C7N77_RS05985	COG3047	cAMP biosynthetic process
C7N77_RS06015	COG3135	benzoate transporter
C7N77_RS06020	COG1396	sequence-specific DNA binding
C7N77_RS06050	COG2926	Belongs to the UPF0265 family
C7N77_RS06060	COG3028	Belongs to the UPF0307 family
C7N77_RS06065	COG0312	modulator of DNA gyrase
C7N77_RS06070	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C7N77_RS06075	COG5007	Belongs to the BolA IbaG family
C7N77_RS06085	COG2854	intermembrane phospholipid transfer
C7N77_RS06090	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7N77_RS06095	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7N77_RS06100	COG1127	ABC transporter
C7N77_RS06105	COG0517	IMP dehydrogenase activity
C7N77_RS06105	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C7N77_RS06110	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C7N77_RS06115	COG3117	lipopolysaccharide transmembrane transporter activity
C7N77_RS06120	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C7N77_RS06125	COG1137	ATPase activity
C7N77_RS06140	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS06145	COG1660	Displays ATPase and GTPase activities
C7N77_RS06150	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS06155	COG3711	transcriptional antiterminator
C7N77_RS06155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS06170	COG3964	amidohydrolase
C7N77_RS06200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7N77_RS06205	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C7N77_RS06220	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C7N77_RS06225	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C7N77_RS06230	COG0723	plastoquinol--plastocyanin reductase activity
C7N77_RS06235	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C7N77_RS06240	COG2857	Cytochrome c1
C7N77_RS06245	COG0625	glutathione transferase activity
C7N77_RS06250	COG2969	positive regulation of protein catabolic process
C7N77_RS06255	COG2823	Periplasmic or secreted lipoprotein
C7N77_RS06260	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7N77_RS06265	COG0792	nuclease activity
C7N77_RS06270	COG3107	peptidoglycan biosynthetic process
C7N77_RS06275	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C7N77_RS06285	COG2001	Belongs to the MraZ family
C7N77_RS06290	COG0275	rRNA processing
C7N77_RS06295	COG3116	cell division
C7N77_RS06300	COG0768	penicillin binding
C7N77_RS06305	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
C7N77_RS06310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C7N77_RS06315	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7N77_RS06320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C7N77_RS06325	COG0772	Belongs to the SEDS family
C7N77_RS06330	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7N77_RS06335	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7N77_RS06340	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C7N77_RS06345	COG0849	cell division
C7N77_RS06350	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C7N77_RS06355	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C7N77_RS06365	COG0653	protein targeting
C7N77_RS06370	COG0494	nUDIX hydrolase
C7N77_RS06375	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C7N77_RS06380	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C7N77_RS06395	COG1459	type II secretion system
C7N77_RS06400	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7N77_RS06430	COG2186	Transcriptional regulator
C7N77_RS06435	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C7N77_RS06440	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7N77_RS06445	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C7N77_RS06450	COG0840	transmembrane signaling receptor activity
C7N77_RS06455	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7N77_RS06460	COG1049	propionate catabolic process, 2-methylcitrate cycle
C7N77_RS06465	COG2200	EAL domain
C7N77_RS06470	COG2200	EAL domain
C7N77_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS06480	COG0583	DNA-binding transcription factor activity
C7N77_RS06490	COG1280	lysine exporter protein (LysE YggA)
C7N77_RS06500	COG0523	cobalamin synthesis protein
C7N77_RS06505	COG0477	Major facilitator Superfamily
C7N77_RS06520	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C7N77_RS06525	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C7N77_RS06575	COG1522	sequence-specific DNA binding
C7N77_RS06580	COG0110	maltose O-acetyltransferase activity
C7N77_RS06585	COG0366	Alpha amylase catalytic
C7N77_RS06590	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N77_RS06590	COG1263	PTS System
C7N77_RS06595	COG1609	Transcriptional regulator
C7N77_RS06605	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7N77_RS06610	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7N77_RS06615	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7N77_RS06615	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7N77_RS06620	COG2723	6-phospho-beta-galactosidase activity
C7N77_RS06625	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7N77_RS06630	COG1940	carbohydrate kinase activity
C7N77_RS06640	COG1609	Transcriptional regulator
C7N77_RS06650	COG0252	asparaginase activity
C7N77_RS06665	COG1803	Methylglyoxal synthase
C7N77_RS06685	COG1444	tRNA N-acetyltransferase activity
C7N77_RS06690	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7N77_RS06700	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
C7N77_RS06730	COG0109	protoheme IX farnesyltransferase activity
C7N77_RS06735	COG1012	belongs to the aldehyde dehydrogenase family
C7N77_RS06740	COG1177	transmembrane transport
C7N77_RS06745	COG1176	ABC-type spermidine putrescine transport system, permease component I
C7N77_RS06750	COG3842	ATPase activity
C7N77_RS06755	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
C7N77_RS06760	COG0583	DNA-binding transcription factor activity
C7N77_RS06765	COG1757	Na H antiporter
C7N77_RS06805	COG0297	glycogen (starch) synthase activity
C7N77_RS06810	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7N77_RS06815	COG2813	Specifically methylates the guanine in position
C7N77_RS06820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C7N77_RS06825	COG5001	Diguanylate cyclase
C7N77_RS06825	COG2203	Gaf domain
C7N77_RS06825	COG4251	negative regulation of phosphorylation
C7N77_RS06825	COG3706	GGDEF domain
C7N77_RS06830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N77_RS06840	COG2995	paraquat-inducible protein a
C7N77_RS06845	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C7N77_RS06845	COG3008	intermembrane lipid transfer
C7N77_RS06850	COG3009	Protein conserved in bacteria
C7N77_RS06860	COG3240	lipase activity
C7N77_RS06875	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C7N77_RS06880	COG1194	a g-specific adenine glycosylase
C7N77_RS06890	COG3409	Peptidoglycan-binding domain 1 protein
C7N77_RS06890	COG3267	Type II secretory pathway component ExeA
C7N77_RS06895	COG0617	tRNA 3'-terminal CCA addition
C7N77_RS06900	COG0306	phosphate transporter
C7N77_RS06905	COG1392	Phosphate transport regulator
C7N77_RS06910	COG3025	triphosphatase activity
C7N77_RS06915	COG3133	Outer membrane lipoprotein
C7N77_RS06935	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C7N77_RS06940	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C7N77_RS06950	COG3031	protein transport across the cell outer membrane
C7N77_RS06955	COG1450	Type ii and iii secretion system protein
C7N77_RS06960	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C7N77_RS06965	COG1459	type II secretion system
C7N77_RS06970	COG2165	general secretion pathway protein
C7N77_RS06980	COG2165	general secretion pathway protein
C7N77_RS06985	COG4795	General secretion pathway protein
C7N77_RS06990	COG3156	type II secretion system protein K
C7N77_RS07000	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C7N77_RS07010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7N77_RS07015	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C7N77_RS07020	COG2723	6-phospho-beta-galactosidase activity
C7N77_RS07025	COG1447	Phosphotransferase system cellobiose-specific component IIA
C7N77_RS07030	COG1917	Cupin 2, conserved barrel domain protein
C7N77_RS07030	COG2169	Transcriptional regulator
C7N77_RS07035	COG1486	melibiose metabolic process
C7N77_RS07050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7N77_RS07055	COG1011	Hydrolase
C7N77_RS07060	COG0494	nUDIX hydrolase
C7N77_RS07065	COG1218	3'(2'),5'-bisphosphate nucleotidase
C7N77_RS07070	COG0814	amino acid
C7N77_RS07075	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7N77_RS07090	COG0626	cystathionine gamma-synthase activity
C7N77_RS07095	COG0460	homoserine dehydrogenase
C7N77_RS07095	COG0527	aspartate kinase activity
C7N77_RS07100	COG1346	cytolysis
C7N77_RS07105	COG1380	Effector of murein hydrolase LrgA
C7N77_RS07110	COG0583	DNA-binding transcription factor activity
C7N77_RS07160	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C7N77_RS07165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7N77_RS07175	COG0137	argininosuccinate synthase activity
C7N77_RS07180	COG0165	Argininosuccinate lyase
C7N77_RS07185	COG0583	DNA-binding transcription factor activity
C7N77_RS07195	COG1942	4-Oxalocrotonate Tautomerase
C7N77_RS07220	COG0642	Histidine kinase
C7N77_RS07225	COG1653	transport
C7N77_RS07230	COG1263	PTS System
C7N77_RS07230	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N77_RS07240	COG0110	maltose O-acetyltransferase activity
C7N77_RS07245	COG3174	membrane
C7N77_RS07250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS07255	COG1126	abc transporter atp-binding protein
C7N77_RS07260	COG0765	amino acid transport
C7N77_RS07265	COG0765	amino acid transport
C7N77_RS07270	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C7N77_RS07275	COG1505	serine-type exopeptidase activity
C7N77_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS07295	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C7N77_RS07310	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7N77_RS07315	COG4991	sh3 domain protein
C7N77_RS07320	COG2816	NAD+ diphosphatase activity
C7N77_RS07325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C7N77_RS07330	COG1940	carbohydrate kinase activity
C7N77_RS07335	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7N77_RS07340	COG0126	phosphoglycerate kinase activity
C7N77_RS07345	COG0191	fructose-bisphosphate aldolase activity
C7N77_RS07350	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7N77_RS07400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C7N77_RS07405	COG1595	DNA-templated transcription, initiation
C7N77_RS07415	COG3026	antisigma factor binding
C7N77_RS07425	COG0481	GTPase activity
C7N77_RS07430	COG0681	Belongs to the peptidase S26 family
C7N77_RS07435	COG0571	ribonuclease III activity
C7N77_RS07445	COG1381	Involved in DNA repair and RecF pathway recombination
C7N77_RS07450	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C7N77_RS07455	COG3023	N-Acetylmuramoyl-L-alanine amidase
C7N77_RS07460	COG4807	Protein conserved in bacteria
C7N77_RS07470	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C7N77_RS07475	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C7N77_RS07480	COG3956	TIGRFAM MazG family protein
C7N77_RS07485	COG0504	CTP synthase activity
C7N77_RS07490	COG0148	phosphopyruvate hydratase activity
C7N77_RS07495	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C7N77_RS07500	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C7N77_RS07510	COG0585	pseudouridine synthase activity
C7N77_RS07515	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C7N77_RS07520	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C7N77_RS07525	COG1238	metal cluster binding
C7N77_RS07530	COG1388	LysM domain
C7N77_RS07530	COG4942	peptidase
C7N77_RS07540	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C7N77_RS07545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C7N77_RS07550	COG1610	YqeY-like protein
C7N77_RS07555	COG0358	DNA primase activity
C7N77_RS07560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C7N77_RS07590	COG0151	Belongs to the GarS family
C7N77_RS07595	COG0138	bifunctional purine biosynthesis protein purh
C7N77_RS07610	COG3036	rescue of stalled ribosome
C7N77_RS07615	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C7N77_RS07620	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C7N77_RS07630	COG0673	inositol 2-dehydrogenase activity
C7N77_RS07640	COG1585	Membrane protein implicated in regulation of membrane protease activity
C7N77_RS07645	COG0330	HflC and HflK could
C7N77_RS07650	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C7N77_RS07650	COG1648	precorrin-2 dehydrogenase activity
C7N77_RS07655	COG0175	sulfate reduction
C7N77_RS07660	COG2895	sulfate adenylyltransferase (ATP) activity
C7N77_RS07665	COG3273	potassium ion transport
C7N77_RS07665	COG0471	metal ion transport
C7N77_RS07670	COG0529	Catalyzes the synthesis of activated sulfate
C7N77_RS07700	COG1136	(ABC) transporter
C7N77_RS07715	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C7N77_RS07730	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C7N77_RS07735	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C7N77_RS07740	COG0163	prenyltransferase activity
C7N77_RS07755	COG1131	(ABC) transporter
C7N77_RS07760	COG0842	Transport permease protein
C7N77_RS07770	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C7N77_RS07775	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C7N77_RS07785	COG0617	tRNA 3'-terminal CCA addition
C7N77_RS07790	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7N77_RS07795	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C7N77_RS07800	COG1489	DNA binding
C7N77_RS07810	COG1643	Atp-dependent helicase
C7N77_RS07815	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7N77_RS07820	COG0346	lactoylglutathione lyase activity
C7N77_RS07830	COG2076	Multidrug Resistance protein
C7N77_RS07835	COG0583	DNA-binding transcription factor activity
C7N77_RS07845	COG0671	phosphoesterase, PA-phosphatase related
C7N77_RS07860	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7N77_RS07865	COG0038	chloride channel
C7N77_RS07875	COG0316	Belongs to the HesB IscA family
C7N77_RS07915	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C7N77_RS07920	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C7N77_RS07925	COG1178	ABC-type Fe3 transport system permease component
C7N77_RS07950	COG0066	3-isopropylmalate dehydratase activity
C7N77_RS07955	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C7N77_RS07960	COG0473	3-isopropylmalate dehydrogenase activity
C7N77_RS07965	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7N77_RS07975	COG0671	phosphoesterase, PA-phosphatase related
C7N77_RS07980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C7N77_RS07990	COG0028	Belongs to the TPP enzyme family
C7N77_RS08000	COG0440	acetolactate synthase activity
C7N77_RS08005	COG0280	phosphate acetyltransferase
C7N77_RS08005	COG0857	belongs to the CobB CobQ family
C7N77_RS08010	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C7N77_RS08020	COG3013	Belongs to the UPF0304 family
C7N77_RS08025	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C7N77_RS08030	COG2716	regulation of RNA biosynthetic process
C7N77_RS08040	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C7N77_RS08045	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C7N77_RS08080	COG5002	protein histidine kinase activity
C7N77_RS08080	COG0784	Response regulator, receiver
C7N77_RS08080	COG2198	Histidine kinase
C7N77_RS08085	COG0232	Belongs to the dGTPase family. Type 2 subfamily
C7N77_RS08095	COG2205	protein histidine kinase activity
C7N77_RS08095	COG0784	Response regulator, receiver
C7N77_RS08105	COG0840	transmembrane signaling receptor activity
C7N77_RS08120	COG1464	Belongs to the NlpA lipoprotein family
C7N77_RS08125	COG2011	ABC-type metal ion transport system permease component
C7N77_RS08130	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
C7N77_RS08150	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
C7N77_RS08150	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
C7N77_RS08155	COG0802	atpase or kinase
C7N77_RS08165	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C7N77_RS08170	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C7N77_RS08175	COG1923	regulation of RNA biosynthetic process
C7N77_RS08180	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C7N77_RS08185	COG0330	HflC and HflK could
C7N77_RS08190	COG0330	HflC and HflK could
C7N77_RS08195	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C7N77_RS08200	COG0142	geranyltranstransferase activity
C7N77_RS08205	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C7N77_RS08210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C7N77_RS08215	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C7N77_RS08220	COG3314	Sporulation integral membrane protein YlbJ
C7N77_RS08225	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C7N77_RS08230	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C7N77_RS08240	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7N77_RS08245	COG2967	ApaG domain
C7N77_RS08250	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C7N77_RS08255	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C7N77_RS08265	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C7N77_RS08270	COG3178	'Phosphotransferase
C7N77_RS08275	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C7N77_RS08280	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C7N77_RS08285	COG2252	PERMEase
C7N77_RS08295	COG0488	(ABC) transporter
C7N77_RS08300	COG0741	lytic transglycosylase activity
C7N77_RS08305	COG0463	Glycosyl transferase, family 2
C7N77_RS08315	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C7N77_RS08340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N77_RS08350	COG3721	Heme iron utilization protein
C7N77_RS08355	COG0748	coenzyme F420 binding
C7N77_RS08380	COG2814	Major facilitator Superfamily
C7N77_RS08385	COG2205	protein histidine kinase activity
C7N77_RS08420	COG1765	OsmC-like protein
C7N77_RS08435	COG3954	Phosphoribulokinase
C7N77_RS08440	COG3089	Belongs to the UPF0270 family
C7N77_RS08445	COG5001	Diguanylate cyclase
C7N77_RS08445	COG3706	GGDEF domain
C7N77_RS08445	COG2203	Gaf domain
C7N77_RS08445	COG4251	negative regulation of phosphorylation
C7N77_RS08450	COG0429	hydrolase of the alpha beta-hydrolase fold
C7N77_RS08455	COG0784	Response regulator, receiver
C7N77_RS08455	COG0835	chemotaxis
C7N77_RS08465	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C7N77_RS08470	COG1047	Peptidyl-prolyl cis-trans
C7N77_RS08485	COG0545	Peptidyl-prolyl cis-trans isomerase
C7N77_RS08490	COG2204	response regulator
C7N77_RS08510	COG0737	Belongs to the 5'-nucleotidase family
C7N77_RS08525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7N77_RS08530	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7N77_RS08530	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C7N77_RS08530	COG0506	proline dehydrogenase activity
C7N77_RS08540	COG0114	fumarate hydratase activity
C7N77_RS08550	COG1566	PFAM secretion protein HlyD family protein
C7N77_RS08620	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7N77_RS08630	COG1280	lysine exporter protein (LysE YggA)
C7N77_RS08645	COG0826	peptidase U32
C7N77_RS08660	COG3813	Protein conserved in bacteria
C7N77_RS08680	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C7N77_RS08705	COG0300	oxidoreductase activity
C7N77_RS08715	COG0840	transmembrane signaling receptor activity
C7N77_RS08725	COG2610	gluconate transmembrane transporter activity
C7N77_RS08730	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7N77_RS08735	COG3622	Belongs to the hyi family
C7N77_RS08740	COG0235	Class ii aldolase
C7N77_RS08745	COG3395	kinase activity
C7N77_RS08750	COG2084	Dehydrogenase
C7N77_RS08755	COG1349	DNA-binding transcription factor activity
C7N77_RS08765	COG2133	pyrroloquinoline quinone binding
C7N77_RS08805	COG0077	Prephenate dehydratase
C7N77_RS08805	COG1605	Chorismate mutase
C7N77_RS08830	COG3272	Protein of unknown function (DUF1722)
C7N77_RS08835	COG0789	Transcriptional regulator
C7N77_RS08840	COG0415	Belongs to the DNA photolyase family
C7N77_RS08850	COG0300	oxidoreductase activity
C7N77_RS08865	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C7N77_RS08890	COG0783	Belongs to the Dps family
C7N77_RS08895	COG1151	hydroxylamine reductase activity
C7N77_RS08900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N77_RS08905	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C7N77_RS08925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N77_RS08930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N77_RS08935	COG0745	RESPONSE REGULATOR receiver
C7N77_RS08940	COG5002	protein histidine kinase activity
C7N77_RS08975	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C7N77_RS08985	COG0798	PFAM Bile acid sodium symporter
C7N77_RS08990	COG1393	Belongs to the ArsC family
C7N77_RS08995	COG2072	flavoprotein involved in K transport
C7N77_RS09010	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C7N77_RS09015	COG1666	GTP binding
C7N77_RS09020	COG3248	Nucleoside-binding outer membrane protein
C7N77_RS09025	COG2211	Major facilitator Superfamily
C7N77_RS09035	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7N77_RS09045	COG2813	Specifically methylates the guanine in position
C7N77_RS09050	COG0271	Belongs to the BolA IbaG family
C7N77_RS09055	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7N77_RS09060	COG1805	sodium ion transport
C7N77_RS09065	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7N77_RS09070	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7N77_RS09075	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7N77_RS09080	COG2871	sodium ion transport
C7N77_RS09085	COG1477	protein flavinylation
C7N77_RS09100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C7N77_RS09105	COG0840	transmembrane signaling receptor activity
C7N77_RS09110	COG0583	DNA-binding transcription factor activity
C7N77_RS09120	COG2363	Small membrane protein
C7N77_RS09125	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C7N77_RS09135	COG0473	3-isopropylmalate dehydrogenase activity
C7N77_RS09140	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C7N77_RS09145	COG1611	Belongs to the LOG family
C7N77_RS09160	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7N77_RS09160	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C7N77_RS09170	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C7N77_RS09195	COG3098	single-species biofilm formation
C7N77_RS09200	COG0564	pseudouridine synthase activity
C7N77_RS09205	COG0716	FMN binding
C7N77_RS09210	COG4580	involved in the transport of maltose and maltodextrins
C7N77_RS09220	COG1263	PTS System
C7N77_RS09220	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N77_RS09230	COG2171	N-acyltransferase activity
C7N77_RS09235	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C7N77_RS09240	COG0024	Methionine aminopeptidase
C7N77_RS09245	COG0052	Belongs to the universal ribosomal protein uS2 family
C7N77_RS09250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C7N77_RS09255	COG0528	UMP kinase activity
C7N77_RS09260	COG0233	cytoplasmic translational termination
C7N77_RS09265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C7N77_RS09270	COG0575	Belongs to the CDS family
C7N77_RS09275	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C7N77_RS09280	COG0750	zinc metalloprotease
C7N77_RS09295	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7N77_RS09300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7N77_RS09305	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7N77_RS09310	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7N77_RS09315	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C7N77_RS09325	COG0825	malonyl-CoA metabolic process
C7N77_RS09355	COG0583	DNA-binding transcription factor activity
C7N77_RS09360	COG0814	amino acid
C7N77_RS09365	COG0531	amino acid
C7N77_RS09385	COG3590	peptidase
C7N77_RS09390	COG0037	tRNA processing
C7N77_RS09395	COG3706	GGDEF domain
C7N77_RS09430	COG0366	Alpha amylase catalytic
C7N77_RS09445	COG0463	Glycosyl transferase, family 2
C7N77_RS09460	COG2989	Protein conserved in bacteria
C7N77_RS09465	COG3108	Peptidase M15
C7N77_RS09475	COG2860	membrane
C7N77_RS09485	COG1196	nuclear chromosome segregation
C7N77_RS09490	COG3115	cell septum assembly
C7N77_RS09495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C7N77_RS09505	COG1328	CTP reductase activity
C7N77_RS09510	COG0602	queuosine metabolic process
C7N77_RS09535	COG1566	PFAM secretion protein HlyD family protein
C7N77_RS09540	COG1846	Transcriptional regulator
C7N77_RS09550	COG0281	malic enzyme
C7N77_RS09555	COG3290	protein histidine kinase activity
C7N77_RS09565	COG0697	spore germination
C7N77_RS09580	COG3284	Transcriptional regulator
C7N77_RS09585	COG3706	GGDEF domain
C7N77_RS09590	COG0346	lactoylglutathione lyase activity
C7N77_RS09595	COG0745	RESPONSE REGULATOR receiver
C7N77_RS09600	COG5002	protein histidine kinase activity
C7N77_RS09610	COG4783	chaperone-mediated protein folding
C7N77_RS09620	COG1940	carbohydrate kinase activity
C7N77_RS09630	COG0545	Peptidyl-prolyl cis-trans isomerase
C7N77_RS09650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS09655	COG4597	amino acid ABC transporter
C7N77_RS09660	COG0765	amino acid transport
C7N77_RS09665	COG1126	abc transporter atp-binding protein
C7N77_RS09675	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
C7N77_RS09680	COG0678	peroxiredoxin activity
C7N77_RS09690	COG0019	diaminopimelate decarboxylase activity
C7N77_RS09695	COG1115	amino acid carrier protein
C7N77_RS09700	COG0095	Lipoate-protein ligase
C7N77_RS09720	COG0534	Mate efflux family protein
C7N77_RS09725	COG2207	Transcriptional regulator
C7N77_RS09730	COG0281	malic enzyme
C7N77_RS09760	COG0733	neurotransmitter:sodium symporter activity
C7N77_RS09765	COG1752	Esterase of the alpha-beta hydrolase superfamily
C7N77_RS09770	COG3706	GGDEF domain
C7N77_RS09780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N77_RS09825	COG0673	inositol 2-dehydrogenase activity
C7N77_RS09830	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C7N77_RS09835	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7N77_RS09860	COG0741	lytic transglycosylase activity
C7N77_RS09860	COG0739	heme binding
C7N77_RS09860	COG1196	nuclear chromosome segregation
C7N77_RS09885	COG0788	formyltetrahydrofolate deformylase activity
C7N77_RS09890	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7N77_RS09900	COG3118	belongs to the thioredoxin family
C7N77_RS09910	COG0791	NLP P60 protein
C7N77_RS09915	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C7N77_RS09930	COG1376	ErfK ybiS ycfS ynhG family protein
C7N77_RS09930	COG1388	LysM domain
C7N77_RS09940	COG1064	alcohol dehydrogenase
C7N77_RS09975	COG0784	Response regulator, receiver
C7N77_RS09975	COG2205	protein histidine kinase activity
C7N77_RS10000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS10000	COG2205	protein histidine kinase activity
C7N77_RS10005	COG3384	dioxygenase
C7N77_RS10015	COG1283	sodium-dependent phosphate transmembrane transporter activity
C7N77_RS10025	COG0531	amino acid
C7N77_RS10030	COG0531	amino acid
C7N77_RS10045	COG1917	Cupin 2, conserved barrel domain protein
C7N77_RS10045	COG1396	sequence-specific DNA binding
C7N77_RS10050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7N77_RS10085	COG4651	solute:proton antiporter activity
C7N77_RS10085	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C7N77_RS10100	COG2974	May be involved in recombination
C7N77_RS10105	COG0456	acetyltransferase
C7N77_RS10110	COG0420	3'-5' exonuclease activity
C7N77_RS10115	COG0419	ATPase involved in DNA repair
C7N77_RS10120	COG3038	cytochrome b561
C7N77_RS10125	COG2190	(PTS) system
C7N77_RS10135	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS10140	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C7N77_RS10145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
C7N77_RS10160	COG1720	tRNA m6t6A37 methyltransferase activity
C7N77_RS10180	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C7N77_RS10185	COG4988	ABC transporter
C7N77_RS10200	COG0745	RESPONSE REGULATOR receiver
C7N77_RS10210	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C7N77_RS10225	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
C7N77_RS10230	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C7N77_RS10245	COG0083	homoserine kinase activity
C7N77_RS10255	COG4319	ketosteroid isomerase
C7N77_RS10280	COG3220	belongs to the UPF0276 family
C7N77_RS10310	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C7N77_RS10315	COG1289	transmembrane transporter activity
C7N77_RS10320	COG1763	Mo-molybdopterin cofactor biosynthetic process
C7N77_RS10325	COG0746	molybdenum cofactor guanylyltransferase activity
C7N77_RS10330	COG0281	malic enzyme
C7N77_RS10355	COG2706	6-phosphogluconolactonase activity
C7N77_RS10365	COG3264	Mechanosensitive ion channel
C7N77_RS10365	COG1196	nuclear chromosome segregation
C7N77_RS10370	COG0469	pyruvate kinase activity
C7N77_RS10375	COG2850	peptidyl-arginine hydroxylation
C7N77_RS10380	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C7N77_RS10385	COG2915	High frequency lysogenization protein hflD homolog
C7N77_RS10390	COG0482	sulfurtransferase activity
C7N77_RS10410	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N77_RS10420	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS10420	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N77_RS10420	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N77_RS10425	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7N77_RS10440	COG1940	carbohydrate kinase activity
C7N77_RS10445	COG0457	Tetratricopeptide repeat
C7N77_RS10450	COG2814	Major facilitator Superfamily
C7N77_RS10450	COG0477	Major facilitator Superfamily
C7N77_RS10460	COG4932	domain protein
C7N77_RS10460	COG5492	domain, Protein
C7N77_RS10465	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N77_RS10480	COG1482	cell wall glycoprotein biosynthetic process
C7N77_RS10485	COG2207	Transcriptional regulator
C7N77_RS10490	COG0538	isocitrate dehydrogenase activity
C7N77_RS10500	COG3048	D-serine ammonia-lyase activity
C7N77_RS10505	COG2610	gluconate transmembrane transporter activity
C7N77_RS10510	COG0583	DNA-binding transcription factor activity
C7N77_RS10515	COG2916	Histone family protein nucleoid-structuring protein H-NS
C7N77_RS10520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7N77_RS10525	COG2375	cellular response to nickel ion
C7N77_RS10540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N77_RS10550	COG1227	inorganic diphosphatase activity
C7N77_RS10555	COG0497	DNA recombination
C7N77_RS10560	COG3706	GGDEF domain
C7N77_RS10565	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C7N77_RS10570	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C7N77_RS10575	COG0443	Heat shock 70 kDa protein
C7N77_RS10580	COG0484	heat shock protein binding
C7N77_RS10610	COG1285	pathogenesis
C7N77_RS10635	COG2391	methyltransferase activity
C7N77_RS10655	COG1136	(ABC) transporter
C7N77_RS10655	COG0577	efflux transmembrane transporter activity
C7N77_RS10660	COG1136	(ABC) transporter
C7N77_RS10660	COG0577	efflux transmembrane transporter activity
C7N77_RS10665	COG1136	(ABC) transporter
C7N77_RS10665	COG0577	efflux transmembrane transporter activity
C7N77_RS10685	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N77_RS10690	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N77_RS10700	COG0708	Exodeoxyribonuclease III
C7N77_RS10715	COG0071	Belongs to the small heat shock protein (HSP20) family
C7N77_RS10725	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
C7N77_RS10750	COG0583	DNA-binding transcription factor activity
C7N77_RS10755	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7N77_RS10760	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C7N77_RS10765	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C7N77_RS10770	COG1845	cytochrome c oxidase, subunit III
C7N77_RS10775	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
C7N77_RS10780	COG0109	protoheme IX farnesyltransferase activity
C7N77_RS10785	COG2814	Major facilitator Superfamily
C7N77_RS10800	COG0583	DNA-binding transcription factor activity
C7N77_RS10820	COG3550	peptidyl-serine autophosphorylation
C7N77_RS10825	COG1396	sequence-specific DNA binding
C7N77_RS10830	COG1988	membrane-bound metal-dependent
C7N77_RS10850	COG0159	tryptophan synthase activity
C7N77_RS10855	COG0133	tryptophan synthase activity
C7N77_RS10860	COG0135	phosphoribosylanthranilate isomerase activity
C7N77_RS10860	COG0134	indole-3-glycerol-phosphate synthase activity
C7N77_RS10865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7N77_RS10870	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C7N77_RS10870	COG0512	Glutamine amidotransferase of anthranilate synthase
C7N77_RS10875	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C7N77_RS10885	COG0613	PHP domain protein
C7N77_RS10890	COG0009	L-threonylcarbamoyladenylate synthase
C7N77_RS10900	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C7N77_RS10910	COG1946	Acyl-CoA thioesterase
C7N77_RS10925	COG1309	transcriptional regulator
C7N77_RS10930	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C7N77_RS10945	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C7N77_RS10955	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C7N77_RS10965	COG1960	acyl-CoA dehydrogenase activity
C7N77_RS10970	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N77_RS10980	COG0469	pyruvate kinase activity
C7N77_RS10985	COG1737	Transcriptional regulator
C7N77_RS10990	COG0837	glucose binding
C7N77_RS11020	COG2244	polysaccharide biosynthetic process
C7N77_RS11025	COG1216	Glycosyl transferase, family 2
C7N77_RS11035	COG0438	transferase activity, transferring glycosyl groups
C7N77_RS11045	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
C7N77_RS11050	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C7N77_RS11060	COG0662	Cupin 2, conserved barrel domain protein
C7N77_RS11060	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
C7N77_RS11075	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C7N77_RS11135	COG1278	Cold shock
C7N77_RS11165	COG0697	spore germination
C7N77_RS11180	COG1187	pseudouridine synthase activity
C7N77_RS11190	COG4166	transmembrane transport
C7N77_RS11195	COG0622	Phosphoesterase
C7N77_RS11210	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
C7N77_RS11215	COG0835	chemotaxis
C7N77_RS11215	COG0784	Response regulator, receiver
C7N77_RS11220	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C7N77_RS11225	COG1815	bacterial-type flagellum-dependent cell motility
C7N77_RS11240	COG1749	Flagellar hook protein flgE
C7N77_RS11255	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C7N77_RS11265	COG3951	Flagellar rod assembly protein muramidase FlgJ
C7N77_RS11265	COG1705	Flagellar rod assembly protein muramidase FlgJ
C7N77_RS11280	COG2239	Acts as a magnesium transporter
C7N77_RS11290	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C7N77_RS11295	COG2716	regulation of RNA biosynthetic process
C7N77_RS11325	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C7N77_RS11330	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C7N77_RS11335	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C7N77_RS11355	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C7N77_RS11375	COG0590	tRNA wobble adenosine to inosine editing
C7N77_RS11380	COG0573	inorganic phosphate transmembrane transporter activity
C7N77_RS11385	COG0581	inorganic phosphate transmembrane transporter activity
C7N77_RS11390	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C7N77_RS11400	COG1253	flavin adenine dinucleotide binding
C7N77_RS11415	COG0531	amino acid
C7N77_RS11430	COG1126	abc transporter atp-binding protein
C7N77_RS11435	COG0765	amino acid transport
C7N77_RS11440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS11450	COG2271	Major facilitator Superfamily
C7N77_RS11460	COG2197	response regulator
C7N77_RS11465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C7N77_RS11490	COG1785	Belongs to the alkaline phosphatase family
C7N77_RS11495	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C7N77_RS11500	COG0477	Major facilitator Superfamily
C7N77_RS11505	COG0123	including yeast histone deacetylase and acetoin utilization protein
C7N77_RS11515	COG1199	ATP-dependent helicase activity
C7N77_RS11530	COG1448	Aminotransferase
C7N77_RS11535	COG0433	COG0433 Predicted ATPase
C7N77_RS11550	COG2333	competence protein COMEC
C7N77_RS11550	COG0658	competence protein
C7N77_RS11555	COG1132	(ABC) transporter
C7N77_RS11560	COG1663	tetraacyldisaccharide 4'-kinase activity
C7N77_RS11565	COG2835	tetraacyldisaccharide 4'-kinase activity
C7N77_RS11570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C7N77_RS11575	COG2197	response regulator
C7N77_RS11580	COG0322	excinuclease ABC activity
C7N77_RS11685	COG2314	TM2 domain
C7N77_RS11700	COG0604	alcohol dehydrogenase
C7N77_RS11720	COG0625	glutathione transferase activity
C7N77_RS11725	COG2261	transglycosylase associated protein
C7N77_RS11730	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C7N77_RS11740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C7N77_RS11750	COG0419	ATPase involved in DNA repair
C7N77_RS11765	COG2203	Gaf domain
C7N77_RS11765	COG2199	diguanylate cyclase activity
C7N77_RS11800	COG2119	membrane
C7N77_RS11820	COG0023	Translation Initiation Factor
C7N77_RS11870	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
C7N77_RS11875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7N77_RS11880	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C7N77_RS11885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7N77_RS11895	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C7N77_RS11900	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C7N77_RS11910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C7N77_RS11915	COG0505	Belongs to the CarA family
C7N77_RS11920	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C7N77_RS11925	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C7N77_RS11955	COG0513	Belongs to the DEAD box helicase family
C7N77_RS11970	COG0789	Transcriptional regulator
C7N77_RS11975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS11980	COG0765	amino acid transport
C7N77_RS11985	COG1126	abc transporter atp-binding protein
C7N77_RS11990	COG0493	'glutamate synthase
C7N77_RS12000	COG1242	4 iron, 4 sulfur cluster binding
C7N77_RS12070	COG1113	amino acid transport
C7N77_RS12080	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C7N77_RS12085	COG0574	Belongs to the PEP-utilizing enzyme family
C7N77_RS12085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C7N77_RS12100	COG1119	ATPase activity
C7N77_RS12115	COG1464	Belongs to the NlpA lipoprotein family
C7N77_RS12120	COG0671	phosphoesterase, PA-phosphatase related
C7N77_RS12125	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C7N77_RS12130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7N77_RS12140	COG0101	tRNA pseudouridine synthase activity
C7N77_RS12145	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C7N77_RS12150	COG0285	dihydrofolate synthase activity
C7N77_RS12155	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C7N77_RS12160	COG2920	part of a sulfur-relay system
C7N77_RS12165	COG1289	transmembrane transporter activity
C7N77_RS12195	COG3539	Fimbrial protein
C7N77_RS12210	COG3188	usher protein
C7N77_RS12225	COG5492	domain, Protein
C7N77_RS12225	COG4932	domain protein
C7N77_RS12250	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C7N77_RS12260	COG2175	clavaminate synthase activity
C7N77_RS12265	COG3246	L-lysine catabolic process to acetate
C7N77_RS12270	COG2814	Major facilitator Superfamily
C7N77_RS12280	COG2855	membrane
C7N77_RS12325	COG0318	PFAM AMP-dependent synthetase and ligase
C7N77_RS12335	COG3706	GGDEF domain
C7N77_RS12340	COG0564	pseudouridine synthase activity
C7N77_RS12355	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
C7N77_RS12365	COG0625	glutathione transferase activity
C7N77_RS12375	COG0367	asparagine synthase
C7N77_RS12385	COG0647	UMP catabolic process
C7N77_RS12395	COG1902	pentaerythritol trinitrate reductase activity
C7N77_RS12400	COG1253	flavin adenine dinucleotide binding
C7N77_RS12415	COG0247	lactate metabolic process
C7N77_RS12415	COG0277	FAD linked oxidase domain protein
C7N77_RS12425	COG2050	protein possibly involved in aromatic compounds catabolism
C7N77_RS12430	COG0513	Belongs to the DEAD box helicase family
C7N77_RS12435	COG0583	DNA-binding transcription factor activity
C7N77_RS12440	COG2814	Major facilitator Superfamily
C7N77_RS12445	COG2056	Na+-H+ antiporter family
C7N77_RS12450	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N77_RS12460	COG0483	inositol monophosphate 1-phosphatase activity
C7N77_RS12475	COG0625	glutathione transferase activity
C7N77_RS12485	COG0601	transmembrane transport
C7N77_RS12490	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N77_RS12500	COG2814	Major facilitator Superfamily
C7N77_RS12505	COG0673	inositol 2-dehydrogenase activity
C7N77_RS12515	COG1879	ABC-type sugar transport system periplasmic component
C7N77_RS12520	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N77_RS12525	COG1129	ABC transporter
C7N77_RS12530	COG1609	Transcriptional regulator
C7N77_RS12550	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7N77_RS12555	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7N77_RS12560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C7N77_RS12565	COG0509	glycine decarboxylation via glycine cleavage system
C7N77_RS12570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7N77_RS12570	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C7N77_RS12600	COG3634	alkyl hydroperoxide reductase activity
C7N77_RS12610	COG0517	IMP dehydrogenase activity
C7N77_RS12615	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C7N77_RS12620	COG0343	queuine tRNA-ribosyltransferase activity
C7N77_RS12625	COG1862	Preprotein translocase
C7N77_RS12630	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7N77_RS12635	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7N77_RS12650	COG0826	peptidase U32
C7N77_RS12655	COG0826	peptidase U32
C7N77_RS12660	COG3154	lipid carrier protein
C7N77_RS12680	COG1104	cysteine desulfurase activity
C7N77_RS12685	COG0822	iron-sulfur transferase activity
C7N77_RS12695	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C7N77_RS12700	COG0443	Heat shock 70 kDa protein
C7N77_RS12705	COG0633	Ferredoxin
C7N77_RS12715	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7N77_RS12720	COG0105	UTP biosynthetic process
C7N77_RS12725	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C7N77_RS12735	COG1426	Protein conserved in bacteria
C7N77_RS12740	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C7N77_RS12745	COG0124	histidyl-tRNA synthetase
C7N77_RS12750	COG2976	Protein conserved in bacteria
C7N77_RS12755	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N77_RS12760	COG1160	GTP binding
C7N77_RS12765	COG1645	bacterial-type flagellum-dependent swarming motility
C7N77_RS12770	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C7N77_RS12775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C7N77_RS12775	COG0047	phosphoribosylformylglycinamidine synthase activity
C7N77_RS12780	COG1007	ATP synthesis coupled electron transport
C7N77_RS12785	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N77_RS12795	COG0713	ATP synthesis coupled electron transport
C7N77_RS12800	COG0839	Belongs to the complex I subunit 6 family
C7N77_RS12805	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N77_RS12810	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C7N77_RS12815	COG1034	ATP synthesis coupled electron transport
C7N77_RS12830	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N77_RS12830	COG0649	NAD binding
C7N77_RS12835	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N77_RS12840	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C7N77_RS12845	COG1360	Flagellar Motor Protein
C7N77_RS12850	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7N77_RS12870	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C7N77_RS12890	COG0724	RNA recognition motif
C7N77_RS12920	COG3437	response regulator, receiver
C7N77_RS12925	COG0583	DNA-binding transcription factor activity
C7N77_RS12935	COG5001	Diguanylate cyclase
C7N77_RS12935	COG3300	MHYT domain
C7N77_RS12940	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
C7N77_RS12945	COG0778	Nitroreductase
C7N77_RS12970	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C7N77_RS12975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C7N77_RS12980	COG0539	negative regulation of cytoplasmic translation
C7N77_RS12985	COG0776	regulation of translation
C7N77_RS12995	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C7N77_RS13015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C7N77_RS13020	COG0602	queuosine metabolic process
C7N77_RS13025	COG3530	Putative quorum-sensing-regulated virulence factor
C7N77_RS13030	COG2096	Adenosyltransferase
C7N77_RS13035	COG2916	Histone family protein nucleoid-structuring protein H-NS
C7N77_RS13040	COG1757	Na H antiporter
C7N77_RS13045	COG1435	thymidine kinase activity
C7N77_RS13070	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C7N77_RS13090	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C7N77_RS13105	COG2910	NAD(P)H-binding
C7N77_RS13110	COG0583	DNA-binding transcription factor activity
C7N77_RS13120	COG3708	Transcriptional regulator
C7N77_RS13120	COG2207	Transcriptional regulator
C7N77_RS13125	COG3706	GGDEF domain
C7N77_RS13130	COG4774	siderophore transport
C7N77_RS13140	COG0583	DNA-binding transcription factor activity
C7N77_RS13145	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C7N77_RS13155	COG0517	IMP dehydrogenase activity
C7N77_RS13170	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7N77_RS13175	COG3046	protein related to deoxyribodipyrimidine photolyase
C7N77_RS13195	COG3088	subunit of a heme lyase
C7N77_RS13195	COG4235	cytochrome complex assembly
C7N77_RS13205	COG1138	Cytochrome C-type biogenesis protein
C7N77_RS13210	COG3301	Polysulphide reductase, NrfD
C7N77_RS13215	COG0437	4 iron, 4 sulfur cluster binding
C7N77_RS13220	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C7N77_RS13240	COG0247	lactate metabolic process
C7N77_RS13245	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C7N77_RS13250	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C7N77_RS13255	COG3012	SEC-C Motif Domain Protein
C7N77_RS13265	COG1940	carbohydrate kinase activity
C7N77_RS13265	COG1846	Transcriptional regulator
C7N77_RS13270	COG3290	protein histidine kinase activity
C7N77_RS13275	COG4565	transcriptional regulatory protein
C7N77_RS13295	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C7N77_RS13300	COG0569	domain protein
C7N77_RS13300	COG2985	domain, Protein
C7N77_RS13315	COG0556	nucleotide-excision repair
C7N77_RS13325	COG0586	Pfam SNARE associated Golgi protein
C7N77_RS13345	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C7N77_RS13350	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C7N77_RS13360	COG2719	SpoVR family
C7N77_RS13365	COG2718	Belongs to the UPF0229 family
C7N77_RS13370	COG2766	serine protein kinase
C7N77_RS13375	COG0514	ATP-dependent DNA helicase (RecQ)
C7N77_RS13380	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C7N77_RS13385	COG0814	amino acid
C7N77_RS13415	COG0058	SHG alpha-glucan phosphorylase activity
C7N77_RS13425	COG0471	metal ion transport
C7N77_RS13430	COG3118	belongs to the thioredoxin family
C7N77_RS13440	COG1132	(ABC) transporter
C7N77_RS13445	COG1132	(ABC) transporter
C7N77_RS13460	COG2501	S4 domain
C7N77_RS13490	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C7N77_RS13495	COG2329	Antibiotic biosynthesis monooxygenase
C7N77_RS13520	COG1742	UPF0060 membrane protein
C7N77_RS13535	COG0513	Belongs to the DEAD box helicase family
C7N77_RS13540	COG0386	Belongs to the glutathione peroxidase family
C7N77_RS13550	COG1181	Belongs to the D-alanine--D-alanine ligase family
C7N77_RS13560	COG3148	PFAM DTW domain containing protein
C7N77_RS13565	COG0730	response to heat
C7N77_RS13570	COG0583	DNA-binding transcription factor activity
C7N77_RS13585	COG3593	DNA synthesis involved in DNA repair
C7N77_RS13635	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C7N77_RS13640	COG1011	Hydrolase
C7N77_RS13645	COG1473	amidohydrolase
C7N77_RS13650	COG0205	6-phosphofructokinase activity
C7N77_RS13660	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C7N77_RS13665	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7N77_RS13675	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C7N77_RS13680	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7N77_RS13705	COG0588	phosphoglycerate mutase activity
C7N77_RS13735	COG2824	Alkylphosphonate utilization operon protein PhnA
C7N77_RS13770	COG2840	Smr protein MutS2
C7N77_RS13775	COG2890	protein-(glutamine-N5) methyltransferase activity
C7N77_RS13780	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C7N77_RS13790	COG0513	Belongs to the DEAD box helicase family
C7N77_RS13795	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C7N77_RS13800	COG0814	amino acid
C7N77_RS13805	COG1609	Transcriptional regulator
C7N77_RS13810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS13810	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C7N77_RS13815	COG1105	Belongs to the carbohydrate kinase PfkB family
C7N77_RS13820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N77_RS13820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C7N77_RS13820	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C7N77_RS13825	COG3313	Fe-S protein
C7N77_RS13830	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C7N77_RS13835	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C7N77_RS13840	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7N77_RS13845	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C7N77_RS13855	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C7N77_RS13890	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C7N77_RS13895	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C7N77_RS13900	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C7N77_RS13905	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C7N77_RS13910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C7N77_RS13915	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7N77_RS13915	COG0072	phenylalanine-tRNA ligase activity
C7N77_RS13920	COG0776	regulation of translation
C7N77_RS13925	COG2205	protein histidine kinase activity
C7N77_RS13925	COG0784	Response regulator, receiver
C7N77_RS13950	COG3300	MHYT domain
C7N77_RS13950	COG5001	Diguanylate cyclase
C7N77_RS13955	COG1609	Transcriptional regulator
C7N77_RS13960	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N77_RS13965	COG1879	ABC-type sugar transport system periplasmic component
C7N77_RS13970	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N77_RS13975	COG1129	ABC transporter
C7N77_RS13980	COG1869	D-ribose catabolic process
C7N77_RS14000	COG0037	tRNA processing
C7N77_RS14005	COG0589	response to stress
C7N77_RS14010	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C7N77_RS14035	COG2010	Cytochrome c
C7N77_RS14050	COG3278	Belongs to the heme-copper respiratory oxidase family
C7N77_RS14060	COG1956	GAF domain-containing protein
C7N77_RS14065	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C7N77_RS14075	COG0308	aminopeptidase N
C7N77_RS14085	COG2902	Dehydrogenase
C7N77_RS14090	COG0167	dihydroorotate dehydrogenase activity
C7N77_RS14100	COG0116	Belongs to the methyltransferase superfamily
C7N77_RS14100	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7N77_RS14110	COG0488	(ABC) transporter
C7N77_RS14125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C7N77_RS14130	COG1067	ATP-dependent peptidase activity
C7N77_RS14190	COG3141	response to X-ray
C7N77_RS14200	COG2995	paraquat-inducible protein a
C7N77_RS14205	COG3008	intermembrane lipid transfer
C7N77_RS14210	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C7N77_RS14210	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7N77_RS14225	COG0084	hydrolase, TatD family'
C7N77_RS14230	COG0470	DNA polymerase III
C7N77_RS14235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C7N77_RS14240	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C7N77_RS14245	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C7N77_RS14255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C7N77_RS14260	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS14270	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C7N77_RS14275	COG0416	fatty acid biosynthetic process
C7N77_RS14280	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C7N77_RS14285	COG1399	metal-binding, possibly nucleic acid-binding protein
C7N77_RS14295	COG0424	maF-like protein
C7N77_RS14310	COG1530	ribonuclease E activity
C7N77_RS14320	COG0306	phosphate transporter
C7N77_RS14325	COG0717	Belongs to the dCTP deaminase family
C7N77_RS14330	COG0572	uridine kinase
C7N77_RS14335	COG0489	protein tyrosine kinase activity
C7N77_RS14340	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7N77_RS14340	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C7N77_RS14350	COG1254	Belongs to the acylphosphatase family
C7N77_RS14355	COG0840	transmembrane signaling receptor activity
C7N77_RS14365	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C7N77_RS14375	COG0709	Synthesizes selenophosphate from selenide and ATP
C7N77_RS14380	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C7N77_RS14385	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7N77_RS14390	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C7N77_RS14400	COG1643	Atp-dependent helicase
C7N77_RS14405	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C7N77_RS14405	COG0617	tRNA 3'-terminal CCA addition
C7N77_RS14405	COG0517	IMP dehydrogenase activity
C7N77_RS14410	COG2197	response regulator
C7N77_RS14415	COG3314	Sporulation integral membrane protein YlbJ
C7N77_RS14420	COG0583	DNA-binding transcription factor activity
C7N77_RS14430	COG1335	isochorismatase
C7N77_RS14435	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C7N77_RS14440	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C7N77_RS14445	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C7N77_RS14450	COG2832	Protein of unknown function (DUF454)
C7N77_RS14455	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C7N77_RS14465	COG0697	spore germination
C7N77_RS14480	COG0318	PFAM AMP-dependent synthetase and ligase
C7N77_RS14485	COG0596	Alpha beta hydrolase
C7N77_RS14495	COG1214	PFAM Peptidase M22, glycoprotease
C7N77_RS14500	COG1199	ATP-dependent helicase activity
C7N77_RS14510	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C7N77_RS14515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C7N77_RS14520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C7N77_RS14525	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C7N77_RS14525	COG0131	Imidazoleglycerol-phosphate dehydratase
C7N77_RS14530	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C7N77_RS14535	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C7N77_RS14540	COG3437	response regulator, receiver
C7N77_RS14550	COG0784	Response regulator, receiver
C7N77_RS14550	COG2205	protein histidine kinase activity
C7N77_RS14550	COG2198	Histidine kinase
C7N77_RS14555	COG0107	imidazoleglycerol-phosphate synthase activity
C7N77_RS14560	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C7N77_RS14560	COG0140	phosphoribosyl-ATP diphosphatase activity
C7N77_RS14590	COG0318	PFAM AMP-dependent synthetase and ligase
C7N77_RS14595	COG3134	Outer membrane lipoprotein
C7N77_RS14610	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C7N77_RS14630	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N77_RS14655	COG4681	YaeQ
C7N77_RS14665	COG1024	Enoyl-CoA hydratase
C7N77_RS14665	COG1250	3-hydroxyacyl-CoA dehydrogenase
C7N77_RS14670	COG0183	Belongs to the thiolase family
C7N77_RS14675	COG0714	Associated with various cellular activities
C7N77_RS14700	COG2304	oxidoreductase activity
C7N77_RS14720	COG2067	long-chain fatty acid transport protein
C7N77_RS14725	COG2067	long-chain fatty acid transport protein
C7N77_RS14730	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C7N77_RS14750	COG3123	guanosine phosphorylase activity
C7N77_RS14755	COG1760	l-serine dehydratase
C7N77_RS14765	COG1760	l-serine dehydratase
C7N77_RS14770	COG2951	lytic endotransglycosylase activity
C7N77_RS14775	COG3100	YcgL domain-containing protein
C7N77_RS14780	COG0850	regulation of cytokinetic process
C7N77_RS14785	COG2894	cell division
C7N77_RS14790	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C7N77_RS14795	COG3099	Belongs to the UPF0263 family
C7N77_RS14800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C7N77_RS14840	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C7N77_RS14845	COG0697	spore germination
C7N77_RS14850	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C7N77_RS14855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N77_RS14865	COG0307	riboflavin synthase, alpha
C7N77_RS14875	COG0534	Mate efflux family protein
C7N77_RS14905	COG0417	DNA replication proofreading
C7N77_RS14930	COG1560	Kdo2-lipid A biosynthetic process
C7N77_RS14935	COG1560	Kdo2-lipid A biosynthetic process
C7N77_RS14945	COG0583	DNA-binding transcription factor activity
C7N77_RS14950	COG0673	inositol 2-dehydrogenase activity
C7N77_RS14955	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C7N77_RS14970	COG0583	DNA-binding transcription factor activity
C7N77_RS14975	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS14985	COG0583	DNA-binding transcription factor activity
C7N77_RS15000	COG0243	molybdopterin cofactor binding
C7N77_RS15005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C7N77_RS15020	COG1879	ABC-type sugar transport system periplasmic component
C7N77_RS15025	COG1129	ABC transporter
C7N77_RS15035	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N77_RS15045	COG1464	Belongs to the NlpA lipoprotein family
C7N77_RS15050	COG0656	L-ascorbic acid biosynthetic process
C7N77_RS15075	COG5002	protein histidine kinase activity
C7N77_RS15085	COG0667	Aldo Keto reductase
C7N77_RS15095	COG2814	Major facilitator Superfamily
C7N77_RS15110	COG0667	Aldo Keto reductase
C7N77_RS15120	COG0583	DNA-binding transcription factor activity
C7N77_RS15135	COG0583	DNA-binding transcription factor activity
C7N77_RS15145	COG0730	response to heat
C7N77_RS15155	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS15165	COG1024	Enoyl-CoA hydratase
C7N77_RS15170	COG1024	Enoyl-CoA hydratase
C7N77_RS15175	COG1960	acyl-CoA dehydrogenase activity
C7N77_RS15185	COG1960	acyl-CoA dehydrogenase activity
C7N77_RS15190	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C7N77_RS15195	COG1024	Enoyl-CoA hydratase
C7N77_RS15220	COG1584	GPR1 FUN34 yaaH family protein
C7N77_RS15235	COG1115	amino acid carrier protein
C7N77_RS15240	COG1024	Enoyl-CoA hydratase
C7N77_RS15255	COG3162	membrane
C7N77_RS15260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7N77_RS15265	COG0488	(ABC) transporter
C7N77_RS15270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7N77_RS15275	COG0776	regulation of translation
C7N77_RS15280	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C7N77_RS15285	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C7N77_RS15290	COG0740	serine-type endopeptidase activity
C7N77_RS15295	COG0544	peptidyl-prolyl cis-trans isomerase activity
C7N77_RS15310	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C7N77_RS15315	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7N77_RS15320	COG1136	(ABC) transporter
C7N77_RS15325	COG4591	ABC-type transport system involved in lipoprotein release permease component
C7N77_RS15335	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C7N77_RS15340	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C7N77_RS15345	COG4166	transmembrane transport
C7N77_RS15350	COG0697	spore germination
C7N77_RS15360	COG2062	phosphohistidine phosphatase, SixA
C7N77_RS15385	COG3842	ATPase activity
C7N77_RS15405	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C7N77_RS15405	COG0519	Catalyzes the synthesis of GMP from XMP
C7N77_RS15410	COG0517	IMP dehydrogenase activity
C7N77_RS15410	COG0516	GMP reductase activity
C7N77_RS15420	COG0366	Alpha amylase catalytic
C7N77_RS15420	COG1874	Beta-galactosidase
C7N77_RS15445	COG1570	exodeoxyribonuclease VII activity
C7N77_RS15455	COG2885	chlorophyll binding
C7N77_RS15460	COG2199	diguanylate cyclase activity
C7N77_RS15475	COG2154	pterin-4-alpha-carbinolamine dehydratase
C7N77_RS15485	COG3768	UPF0283 membrane protein
C7N77_RS15490	COG3106	COG3106 Predicted ATPase
C7N77_RS15505	COG1842	Phage shock protein A
C7N77_RS15510	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C7N77_RS15520	COG4168	peptide transport system, permease
C7N77_RS15525	COG4171	peptide transport system, permease
C7N77_RS15535	COG4172	Belongs to the ABC transporter superfamily
C7N77_RS15545	COG1609	Transcriptional regulator
C7N77_RS15550	COG1263	PTS System
C7N77_RS15550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N77_RS15555	COG2723	6-phospho-beta-galactosidase activity
C7N77_RS15560	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C7N77_RS15565	COG1286	toxin biosynthetic process
C7N77_RS15570	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C7N77_RS15575	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C7N77_RS15580	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C7N77_RS15585	COG0531	amino acid
C7N77_RS15585	COG1674	ftsk spoiiie
C7N77_RS15595	COG0686	Belongs to the AlaDH PNT family
C7N77_RS15600	COG0492	ferredoxin-NADP+ reductase activity
C7N77_RS15610	COG3134	Outer membrane lipoprotein
C7N77_RS15615	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C7N77_RS15620	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C7N77_RS15625	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C7N77_RS15630	COG0542	response to heat
C7N77_RS15635	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C7N77_RS15640	COG1278	Cold shock
C7N77_RS15645	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C7N77_RS15660	COG1944	ATP diphosphatase activity
C7N77_RS15665	COG2116	formate transmembrane transporter activity
C7N77_RS15675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N77_RS15680	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
C7N77_RS15685	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
C7N77_RS15695	COG1840	ABC-type Fe3 transport system, periplasmic component
C7N77_RS15700	COG3842	ATPase activity
C7N77_RS15710	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7N77_RS15715	COG2983	Belongs to the UPF0260 family
C7N77_RS15720	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C7N77_RS15725	COG0045	succinate-CoA ligase (ADP-forming) activity
C7N77_RS15730	COG0508	dehydrogenase complex catalyzes the overall conversion of
C7N77_RS15735	COG0567	Dehydrogenase, E1 component
C7N77_RS15745	COG1053	succinate dehydrogenase
C7N77_RS15750	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C7N77_RS15775	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C7N77_RS15780	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C7N77_RS15780	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C7N77_RS15790	COG3069	C4-dicarboxylate transmembrane transporter activity
C7N77_RS15805	COG1451	nucleotide metabolic process
C7N77_RS15820	COG0254	rRNA binding
C7N77_RS15825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C7N77_RS15830	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C7N77_RS15840	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
C7N77_RS15865	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS15875	COG1414	Transcriptional regulator
C7N77_RS15880	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N77_RS15885	COG0800	Aldolase
C7N77_RS15895	COG1172	Belongs to the binding-protein-dependent transport system permease family
C7N77_RS15905	COG1879	ABC-type sugar transport system periplasmic component
C7N77_RS15910	COG1069	ribulokinase activity
C7N77_RS15920	COG2160	L-arabinose isomerase activity
C7N77_RS15925	COG0583	DNA-binding transcription factor activity
C7N77_RS15930	COG0436	Aminotransferase
C7N77_RS15935	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C7N77_RS15945	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C7N77_RS15950	COG2925	Exonuclease
C7N77_RS15960	COG3345	alpha-galactosidase
C7N77_RS15965	COG1380	Effector of murein hydrolase LrgA
C7N77_RS15970	COG1346	cytolysis
C7N77_RS15975	COG0295	cytidine deaminase activity
C7N77_RS15980	COG1022	Amp-dependent synthetase and ligase
C7N77_RS15995	COG0861	Integral membrane protein TerC family
C7N77_RS16000	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C7N77_RS16005	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C7N77_RS16010	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C7N77_RS16030	COG0644	oxidoreductase
C7N77_RS16030	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C7N77_RS16055	COG4771	TonB-dependent receptor
C7N77_RS16060	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N77_RS16065	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C7N77_RS16070	COG1120	ATPase activity
C7N77_RS16080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7N77_RS16085	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7N77_RS16085	COG3321	synthase
C7N77_RS16085	COG0300	oxidoreductase activity
C7N77_RS16085	COG0318	PFAM AMP-dependent synthetase and ligase
C7N77_RS16085	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS16095	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS16100	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C7N77_RS16105	COG1535	isochorismatase
C7N77_RS16105	COG3433	isochorismatase activity
C7N77_RS16110	COG1021	2,3-dihydroxybenzoate-AMP ligase
C7N77_RS16130	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C7N77_RS16135	COG5001	Diguanylate cyclase
C7N77_RS16135	COG3300	MHYT domain
C7N77_RS16150	COG0840	transmembrane signaling receptor activity
C7N77_RS16155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N77_RS16165	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C7N77_RS16170	COG0563	adenylate kinase activity
C7N77_RS16175	COG0326	Molecular chaperone. Has ATPase activity
C7N77_RS16180	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C7N77_RS16195	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C7N77_RS16200	COG0298	carbon dioxide binding
C7N77_RS16210	COG0309	Hydrogenase expression formation protein (HypE)
C7N77_RS16215	COG0375	protein maturation
C7N77_RS16220	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C7N77_RS16235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N77_RS16250	COG1773	rubredoxin
C7N77_RS16255	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C7N77_RS16270	COG0437	4 iron, 4 sulfur cluster binding
C7N77_RS16275	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C7N77_RS16290	COG0659	secondary active sulfate transmembrane transporter activity
C7N77_RS16305	COG2308	Evidence 4 Homologs of previously reported genes of
C7N77_RS16340	COG0672	)-iron permease
C7N77_RS16345	COG0493	'glutamate synthase
C7N77_RS16345	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
C7N77_RS16365	COG2814	Major facilitator Superfamily
C7N77_RS16390	COG0577	efflux transmembrane transporter activity
C7N77_RS16435	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C7N77_RS16440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C7N77_RS16440	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C7N77_RS16445	COG0527	aspartate kinase activity
C7N77_RS16455	COG1368	sulfuric ester hydrolase activity
C7N77_RS16460	COG1619	proteins homologs of microcin C7 resistance protein MccF
C7N77_RS16465	COG0393	Putative heavy-metal-binding
C7N77_RS16475	COG3150	esterase
C7N77_RS16490	COG2354	Protein conserved in bacteria
C7N77_RS16500	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7N77_RS16505	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C7N77_RS16540	COG0537	adenosine 5'-monophosphoramidase activity
C7N77_RS16775	COG1846	Transcriptional regulator
C7N77_RS16795	COG3646	Phage regulatory protein
C7N77_RS16795	COG3645	SOS response
C7N77_RS16825	COG5377	YqaJ viral recombinase family
C7N77_RS16855	COG2974	May be involved in recombination
C7N77_RS16900	COG0582	viral genome integration into host DNA
C7N77_RS16905	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C7N77_RS16920	COG1301	dicarboxylic acid transport
C7N77_RS16930	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C7N77_RS16935	COG0861	Integral membrane protein TerC family
C7N77_RS16950	COG0444	Belongs to the ABC transporter superfamily
C7N77_RS16955	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N77_RS16960	COG0601	transmembrane transport
C7N77_RS16970	COG2095	MarC family integral membrane protein
C7N77_RS16975	COG1012	belongs to the aldehyde dehydrogenase family
C7N77_RS16975	COG1454	alcohol dehydrogenase
C7N77_RS16985	COG3275	phosphorelay sensor kinase activity
C7N77_RS16990	COG3279	Response regulator of the LytR AlgR family
C7N77_RS16995	COG1966	Carbon starvation protein
C7N77_RS17000	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C7N77_RS17000	COG3264	Mechanosensitive ion channel
C7N77_RS17010	COG1566	PFAM secretion protein HlyD family protein
C7N77_RS17015	COG1061	Type III restriction enzyme res subunit
C7N77_RS17020	COG2027	D-alanyl-D-alanine carboxypeptidase
C7N77_RS17025	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C7N77_RS17035	COG0436	Aminotransferase
C7N77_RS17045	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C7N77_RS17065	COG0697	spore germination
C7N77_RS17070	COG4657	Part of a membrane complex involved in electron transport
C7N77_RS17075	COG2878	Part of a membrane complex involved in electron transport
C7N77_RS17080	COG4656	Part of a membrane complex involved in electron transport
C7N77_RS17085	COG4658	electron transport chain
C7N77_RS17090	COG4659	FMN binding
C7N77_RS17095	COG4660	Part of a membrane complex involved in electron transport
C7N77_RS17100	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C7N77_RS17105	COG0346	lactoylglutathione lyase activity
C7N77_RS17125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C7N77_RS17135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C7N77_RS17140	COG1086	Polysaccharide biosynthesis protein
C7N77_RS17145	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C7N77_RS17155	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
C7N77_RS17160	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C7N77_RS17175	COG2089	acid synthase
C7N77_RS17180	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N77_RS17230	COG0301	tRNA thio-modification
C7N77_RS17230	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C7N77_RS17240	COG4953	penicillin-binding protein 1C
C7N77_RS17245	COG2373	Large extracellular alpha-helical protein
C7N77_RS17275	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7N77_RS17285	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C7N77_RS17325	COG0438	transferase activity, transferring glycosyl groups
C7N77_RS17325	COG1216	Glycosyl transferase, family 2
C7N77_RS17330	COG1216	Glycosyl transferase, family 2
C7N77_RS17330	COG0438	transferase activity, transferring glycosyl groups
C7N77_RS17340	COG1083	cytidylyl-transferase
C7N77_RS17345	COG0483	inositol monophosphate 1-phosphatase activity
C7N77_RS17350	COG2089	acid synthase
C7N77_RS17380	COG0438	transferase activity, transferring glycosyl groups
C7N77_RS17380	COG1216	Glycosyl transferase, family 2
C7N77_RS17400	COG1091	dTDP-4-dehydrorhamnose reductase activity
C7N77_RS17435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS17445	COG2431	L-lysine efflux transmembrane transporter activity
C7N77_RS17450	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7N77_RS17455	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C7N77_RS17465	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C7N77_RS17480	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7N77_RS17485	COG4783	chaperone-mediated protein folding
C7N77_RS17490	COG0425	Belongs to the sulfur carrier protein TusA family
C7N77_RS17520	COG3842	ATPase activity
C7N77_RS17525	COG3833	ABC-type maltose transport systems, permease component
C7N77_RS17530	COG1175	transmembrane transport
C7N77_RS17540	COG3081	Nucleoid-associated protein
C7N77_RS17545	COG3082	Protein of unknown function (DUF1414)
C7N77_RS17550	COG3083	sulfuric ester hydrolase activity
C7N77_RS17555	COG4771	TonB-dependent receptor
C7N77_RS17560	COG1770	oligopeptidase
C7N77_RS17580	COG4574	serine-type endopeptidase inhibitor activity
C7N77_RS17585	COG3085	chromosome segregation
C7N77_RS17595	COG0287	Prephenate dehydrogenase
C7N77_RS17595	COG1605	Chorismate mutase
C7N77_RS17605	COG0584	glycerophosphoryl diester phosphodiesterase
C7N77_RS17615	COG1349	DNA-binding transcription factor activity
C7N77_RS17620	COG2271	Major facilitator Superfamily
C7N77_RS17625	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C7N77_RS17630	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C7N77_RS17635	COG0583	DNA-binding transcription factor activity
C7N77_RS17655	COG0656	L-ascorbic acid biosynthetic process
C7N77_RS17660	COG2814	Major facilitator Superfamily
C7N77_RS17670	COG1294	oxidase, subunit
C7N77_RS17680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7N77_RS17685	COG2979	Protein of unknown function (DUF533)
C7N77_RS17725	COG2807	transmembrane transport
C7N77_RS17730	COG1187	pseudouridine synthase activity
C7N77_RS17735	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C7N77_RS17785	COG1166	arginine decarboxylase activity
C7N77_RS17800	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7N77_RS17815	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
C7N77_RS17830	COG0583	DNA-binding transcription factor activity
C7N77_RS17840	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C7N77_RS17845	COG0840	transmembrane signaling receptor activity
C7N77_RS17850	COG0302	gtp cyclohydrolase
C7N77_RS17860	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C7N77_RS17865	COG0596	Alpha beta hydrolase
C7N77_RS17870	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C7N77_RS17885	COG0314	molybdopterin synthase activity
C7N77_RS17890	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C7N77_RS17895	COG0315	cyclic pyranopterin monophosphate synthase activity
C7N77_RS17900	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7N77_RS17905	COG3005	denitrification pathway
C7N77_RS17915	COG0348	domain, Protein
C7N77_RS17920	COG0437	4 iron, 4 sulfur cluster binding
C7N77_RS17925	COG0243	molybdopterin cofactor binding
C7N77_RS17935	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N77_RS17940	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C7N77_RS17945	COG3850	Histidine kinase
C7N77_RS17950	COG2197	response regulator
C7N77_RS17975	COG0391	Required for morphogenesis under gluconeogenic growth conditions
C7N77_RS17985	COG0121	glutamine amidotransferase
C7N77_RS17990	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C7N77_RS18000	COG3437	response regulator, receiver
C7N77_RS18000	COG0784	Response regulator, receiver
C7N77_RS18010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C7N77_RS18015	COG0328	RNA-DNA hybrid ribonuclease activity
C7N77_RS18020	COG2226	methyltransferase
C7N77_RS18025	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C7N77_RS18030	COG0741	lytic transglycosylase activity
C7N77_RS18030	COG1388	LysM domain
C7N77_RS18045	COG1607	acyl-coa hydrolase
C7N77_RS18060	COG0741	lytic transglycosylase activity
C7N77_RS18070	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C7N77_RS18095	COG0729	surface antigen
C7N77_RS18105	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C7N77_RS18115	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C7N77_RS18125	COG4134	Bacterial extracellular solute-binding protein
C7N77_RS18135	COG4136	ATPase activity
C7N77_RS18140	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C7N77_RS18145	COG2951	lytic endotransglycosylase activity
C7N77_RS18150	COG1846	Transcriptional regulator
C7N77_RS18160	COG0033	Phosphoglucomutase
C7N77_RS18165	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C7N77_RS18170	COG0596	Alpha beta hydrolase
C7N77_RS18185	COG0716	FMN binding
C7N77_RS18195	COG0735	belongs to the Fur family
C7N77_RS18200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7N77_RS18205	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7N77_RS18210	COG2080	2 iron, 2 sulfur cluster binding
C7N77_RS18215	COG2010	Cytochrome c
C7N77_RS18215	COG1529	Aldehyde oxidase and xanthine dehydrogenase
C7N77_RS18235	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N77_RS18235	COG1263	PTS System
C7N77_RS18235	COG2190	(PTS) system
C7N77_RS18240	COG0363	glucosamine-6-phosphate deaminase activity
C7N77_RS18245	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C7N77_RS18250	COG1846	Transcriptional regulator
C7N77_RS18250	COG1940	carbohydrate kinase activity
C7N77_RS18260	COG0217	transcriptional regulatory protein
C7N77_RS18265	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C7N77_RS18275	COG1801	Protein of unknown function DUF72
C7N77_RS18280	COG4106	trans-aconitate 2-methyltransferase activity
C7N77_RS18285	COG0500	methyltransferase
C7N77_RS18305	COG0583	DNA-binding transcription factor activity
C7N77_RS18310	COG0791	NLP P60 protein
C7N77_RS18325	COG1309	transcriptional regulator
C7N77_RS18360	COG0534	Mate efflux family protein
C7N77_RS18370	COG2841	Protein conserved in bacteria
C7N77_RS18380	COG0674	pyruvate-flavodoxin oxidoreductase activity
C7N77_RS18380	COG1013	pyruvate-flavodoxin oxidoreductase activity
C7N77_RS18380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C7N77_RS18380	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
C7N77_RS18390	COG3217	Mosc domain protein beta barrel domain protein
C7N77_RS18390	COG0633	Ferredoxin
C7N77_RS18390	COG3217	Mosc domain protein beta barrel domain protein
C7N77_RS18390	COG0633	Ferredoxin
C7N77_RS18395	COG0501	Belongs to the peptidase M48B family
C7N77_RS18400	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C7N77_RS18405	COG2226	methyltransferase
C7N77_RS18405	COG1073	alpha beta
C7N77_RS18410	COG0156	8-amino-7-oxononanoate synthase activity
C7N77_RS18415	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C7N77_RS18435	COG0017	Asparaginyl-tRNA synthetase
C7N77_RS18440	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C7N77_RS18455	COG3069	C4-dicarboxylate transmembrane transporter activity
C7N77_RS18470	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7N77_RS18480	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
C7N77_RS18485	COG1393	Belongs to the ArsC family
C7N77_RS18490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C7N77_RS18495	COG1876	peptidase activity
C7N77_RS18505	COG3263	regulation of cellular component size
C7N77_RS18515	COG1280	lysine exporter protein (LysE YggA)
C7N77_RS18545	COG0564	pseudouridine synthase activity
C7N77_RS18555	COG1454	alcohol dehydrogenase
C7N77_RS18560	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C7N77_RS18565	COG0702	epimerase
C7N77_RS18570	COG2914	Belongs to the UPF0125 (RnfH) family
C7N77_RS18575	COG2867	negative regulation of translational initiation
C7N77_RS18580	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C7N77_RS18600	COG3153	acetyltransferase
C7N77_RS18635	COG0259	pyridoxamine-phosphate oxidase activity
C7N77_RS18650	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C7N77_RS18650	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7N77_RS18655	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C7N77_RS18675	COG4235	cytochrome complex assembly
C7N77_RS18675	COG3088	subunit of a heme lyase
C7N77_RS18680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C7N77_RS18685	COG1138	Cytochrome C-type biogenesis protein
C7N77_RS18690	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C7N77_RS18695	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7N77_RS18700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7N77_RS18705	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C7N77_RS18720	COG0835	chemotaxis
C7N77_RS18730	COG1192	Involved in chromosome partitioning
C7N77_RS18735	COG1360	Flagellar Motor Protein
C7N77_RS18740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7N77_RS18745	COG2201	protein-glutamate methylesterase activity
C7N77_RS18750	COG0784	Response regulator, receiver
C7N77_RS18750	COG0643	Histidine kinase
C7N77_RS18750	COG2198	Histidine kinase
C7N77_RS18755	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C7N77_RS18780	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C7N77_RS18790	COG1684	flagellar biosynthetic protein fliR
C7N77_RS18845	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C7N77_RS18855	COG1677	Flagellar hook-basal body complex protein FliE
C7N77_RS18870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7N77_RS18885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C7N77_RS18890	COG0444	Belongs to the ABC transporter superfamily
C7N77_RS18895	COG4608	Belongs to the ABC transporter superfamily
C7N77_RS18905	COG2971	BadF BadG BcrA BcrD
C7N77_RS18915	COG0840	transmembrane signaling receptor activity
C7N77_RS18930	COG3724	N-succinylarginine dihydrolase activity
C7N77_RS18935	COG0616	signal peptide processing
C7N77_RS18940	COG1028	Short-chain dehydrogenase reductase Sdr
C7N77_RS18945	COG0583	DNA-binding transcription factor activity
C7N77_RS18955	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C7N77_RS18970	COG0583	DNA-binding transcription factor activity
C7N77_RS18975	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C7N77_RS18980	COG1881	PFAM PEBP family protein
C7N77_RS18990	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
C7N77_RS18990	COG3408	Glycogen debranching enzyme
C7N77_RS18995	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C7N77_RS19000	COG0739	heme binding
C7N77_RS19005	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C7N77_RS19030	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C7N77_RS19040	COG3091	SprT-like family
C7N77_RS19050	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C7N77_RS19055	COG0189	ligase activity
C7N77_RS19065	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C7N77_RS19085	COG1115	amino acid carrier protein
C7N77_RS19090	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C7N77_RS19105	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C7N77_RS19115	COG1301	dicarboxylic acid transport
C7N77_RS19125	COG2912	Transglutaminase-like superfamily
C7N77_RS19135	COG2890	protein-(glutamine-N5) methyltransferase activity
C7N77_RS19140	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C7N77_RS19145	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C7N77_RS19150	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C7N77_RS19155	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C7N77_RS19165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C7N77_RS19170	COG0737	Belongs to the 5'-nucleotidase family
C7N77_RS19175	COG0193	aminoacyl-tRNA hydrolase activity
C7N77_RS19180	COG0012	GTP binding
C7N77_RS19225	COG0490	domain, Protein
C7N77_RS19225	COG0471	metal ion transport
C7N77_RS19235	COG0657	acetylesterase activity
C7N77_RS19245	COG0366	Alpha amylase catalytic
C7N77_RS19255	COG0488	(ABC) transporter
C7N77_RS19270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N77_RS19280	COG1012	belongs to the aldehyde dehydrogenase family
C7N77_RS19290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C7N77_RS19305	COG0180	Tryptophanyl-tRNA synthetase
C7N77_RS19310	COG0546	phosphoglycolate phosphatase activity
C7N77_RS19315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C7N77_RS19320	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C7N77_RS19330	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C7N77_RS19335	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C7N77_RS19365	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C7N77_RS19370	COG0583	DNA-binding transcription factor activity
C7N77_RS19385	COG0583	DNA-binding transcription factor activity
C7N77_RS19400	COG3121	Chaperone
C7N77_RS19405	COG3188	usher protein
C7N77_RS19410	COG3121	Chaperone
C7N77_RS19420	COG0739	heme binding
C7N77_RS19430	COG1511	domain protein
C7N77_RS19430	COG3264	Mechanosensitive ion channel
C7N77_RS19435	COG0584	glycerophosphoryl diester phosphodiesterase
C7N77_RS19445	COG1053	succinate dehydrogenase
C7N77_RS19450	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C7N77_RS19455	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C7N77_RS19460	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C7N77_RS19465	COG3214	Protein conserved in bacteria
C7N77_RS19470	COG4106	trans-aconitate 2-methyltransferase activity
C7N77_RS19490	COG0300	oxidoreductase activity
C7N77_RS19505	COG0642	Histidine kinase
C7N77_RS19515	COG0516	GMP reductase activity
C7N77_RS19525	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C7N77_RS19530	COG3647	Membrane
C7N77_RS19540	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C7N77_RS19550	COG3706	GGDEF domain
C7N77_RS19560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C7N77_RS19570	COG0583	DNA-binding transcription factor activity
C7N77_RS19575	COG1335	isochorismatase
C7N77_RS19580	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C7N77_RS19585	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C7N77_RS19590	COG1702	phosphate starvation-inducible protein PhoH
C7N77_RS19595	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C7N77_RS19610	COG4535	Mg2 and Co2 transporter CorC
C7N77_RS19615	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C7N77_RS19620	COG2888	peptidyl-tyrosine sulfation
C7N77_RS19625	COG0495	leucyl-tRNA aminoacylation
C7N77_RS19640	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C7N77_RS19645	COG0799	negative regulation of ribosome biogenesis
C7N77_RS19650	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C7N77_RS19655	COG0768	penicillin binding
C7N77_RS19660	COG0772	Belongs to the SEDS family
C7N77_RS19665	COG0772	Belongs to the SEDS family
C7N77_RS19670	COG2951	lytic endotransglycosylase activity
C7N77_RS19675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C7N77_RS19680	COG1686	Belongs to the peptidase S11 family
C7N77_RS19685	COG2921	Belongs to the UPF0250 family
C7N77_RS19690	COG0321	lipoyl(octanoyl) transferase activity
C7N77_RS19700	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C7N77_RS19710	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C7N77_RS19720	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C7N77_RS19730	COG1970	mechanosensitive ion channel activity
C7N77_RS19735	COG4974	Belongs to the 'phage' integrase family
C7N77_RS19770	COG0826	peptidase U32
C7N77_RS19775	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C7N77_RS19780	COG1422	Protein of unknown function (DUF1090)
C7N77_RS19785	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C7N77_RS19790	COG2211	Major facilitator Superfamily
C7N77_RS19795	COG1185	polyribonucleotide nucleotidyltransferase activity
C7N77_RS19800	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C7N77_RS19805	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C7N77_RS19810	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C7N77_RS19815	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C7N77_RS19820	COG0195	Participates in both transcription termination and antitermination
C7N77_RS19825	COG0779	Required for maturation of 30S ribosomal subunits
C7N77_RS19840	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C7N77_RS19845	COG0149	triose-phosphate isomerase activity
C7N77_RS19850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C7N77_RS19855	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C7N77_RS19865	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C7N77_RS19870	COG1534	Rna-binding protein
C7N77_RS19885	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
C7N77_RS19905	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C7N77_RS19910	COG2823	Periplasmic or secreted lipoprotein
C7N77_RS19915	COG1360	Flagellar Motor Protein
C7N77_RS19920	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C7N77_RS19925	COG1722	exodeoxyribonuclease VII activity
C7N77_RS19930	COG0142	geranyltranstransferase activity
C7N77_RS19935	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C7N77_RS19945	COG0601	transmembrane transport
C7N77_RS19955	COG4172	Belongs to the ABC transporter superfamily
C7N77_RS19960	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C7N77_RS19965	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C7N77_RS19970	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C7N77_RS19975	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C7N77_RS19990	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7N77_RS19990	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C7N77_RS19995	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C7N77_RS20005	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C7N77_RS20015	COG0784	Response regulator, receiver
C7N77_RS20015	COG2198	Histidine kinase
C7N77_RS20015	COG2205	protein histidine kinase activity
C7N77_RS20020	COG1879	ABC-type sugar transport system periplasmic component
C7N77_RS20025	COG0745	RESPONSE REGULATOR receiver
C7N77_RS20030	COG3005	denitrification pathway
C7N77_RS20040	COG3381	protein complex oligomerization
C7N77_RS20055	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C7N77_RS20060	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C7N77_RS20065	COG0511	ligase activity, forming carbon-carbon bonds
C7N77_RS20070	COG0439	Biotin carboxylase
C7N77_RS20075	COG3924	membrane
C7N77_RS20080	COG4145	pantothenate transmembrane transporter activity
C7N77_RS20085	COG1263	PTS System
C7N77_RS20085	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C7N77_RS20085	COG2190	(PTS) system
C7N77_RS20090	COG0583	DNA-binding transcription factor activity
C7N77_RS20095	COG0604	alcohol dehydrogenase
C7N77_RS20100	COG2264	protein methyltransferase activity
C7N77_RS20105	COG0110	maltose O-acetyltransferase activity
C7N77_RS20110	COG0778	Nitroreductase
C7N77_RS20115	COG0446	pyridine nucleotide-disulphide oxidoreductase
C7N77_RS20115	COG1902	pentaerythritol trinitrate reductase activity
C7N77_RS20120	COG0616	signal peptide processing
C7N77_RS20140	COG3139	Protein of unknown function (DUF1315)
C7N77_RS20145	COG0252	asparaginase activity
C7N77_RS20150	COG0786	glutamate:sodium symporter activity
C7N77_RS20165	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C7N77_RS20170	COG0384	phenazine biosynthesis protein PhzF
C7N77_RS20180	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7N77_RS20185	COG0175	sulfate reduction
C7N77_RS20190	COG2113	Glycine betaine
C7N77_RS20195	COG4176	ABC-type proline glycine betaine transport system permease component
C7N77_RS20200	COG4175	Glycine betaine
C7N77_RS20210	COG3610	response to peptide
C7N77_RS20215	COG2966	Psort location CytoplasmicMembrane, score
C7N77_RS20225	COG0521	Mo-molybdopterin cofactor biosynthetic process
C7N77_RS20240	COG1858	cytochrome C peroxidase
C7N77_RS20250	COG2313	pseudouridylate synthase activity
C7N77_RS20255	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C7N77_RS20260	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7N77_RS20260	COG2146	nitrite reductase [NAD(P)H] activity
C7N77_RS20265	COG2146	nitrite reductase [NAD(P)H] activity
C7N77_RS20265	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C7N77_RS20270	COG1116	anion transmembrane transporter activity
C7N77_RS20275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
C7N77_RS20280	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
C7N77_RS20280	COG1116	anion transmembrane transporter activity
C7N77_RS20295	COG0243	molybdopterin cofactor binding
C7N77_RS20320	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C7N77_RS20335	COG1073	alpha beta
C7N77_RS20340	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C7N77_RS20355	COG2195	Cleaves the N-terminal amino acid of tripeptides
C7N77_RS20365	COG4608	Belongs to the ABC transporter superfamily
C7N77_RS20370	COG0444	Belongs to the ABC transporter superfamily
C7N77_RS20380	COG4239	(ABC) transporter, permease
C7N77_RS20385	COG4174	ABC transporter (Permease)
C7N77_RS20390	COG4206	TonB-dependent receptor
C7N77_RS20400	COG0811	peptide transport
C7N77_RS20405	COG0811	peptide transport
C7N77_RS20410	COG0848	biopolymer transport protein
C7N77_RS20460	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7N77_RS20465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C7N77_RS20470	COG0840	transmembrane signaling receptor activity
C7N77_RS20480	COG1278	Cold shock
C7N77_RS20520	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C7N77_RS20530	COG0688	phosphatidylethanolamine metabolic process
C7N77_RS20535	COG4628	conserved protein (DUF2132)
C7N77_RS20555	COG3300	MHYT domain
C7N77_RS20555	COG5001	Diguanylate cyclase
C7N77_RS20560	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C7N77_RS20615	COG2897	thiosulfate sulfurtransferase activity
C7N77_RS20620	COG2066	Belongs to the glutaminase family
C7N77_RS20625	COG3171	Protein conserved in bacteria
C7N77_RS20630	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C7N77_RS20635	COG4935	Belongs to the peptidase S8 family
C7N77_RS20635	COG2234	aminopeptidase activity
C7N77_RS20640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C7N77_RS20645	COG2200	EAL domain
C7N77_RS20650	COG1090	epimerase
C7N77_RS20655	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C7N77_RS20660	COG4181	ATPase activity
C7N77_RS20665	COG2755	lipolytic protein G-D-S-L family
C7N77_RS20670	COG0784	Response regulator, receiver
C7N77_RS20670	COG0835	chemotaxis
C7N77_RS20675	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
C7N77_RS20680	COG0516	GMP reductase activity
C7N77_RS20680	COG0517	IMP dehydrogenase activity
C7N77_RS20685	COG0488	(ABC) transporter
C7N77_RS20695	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C7N77_RS20735	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C7N77_RS20740	COG1376	ErfK ybiS ycfS ynhG family protein
C7N77_RS20745	COG0668	transmembrane transport
C7N77_RS20755	COG2731	YhcH YjgK YiaL family protein
C7N77_RS20765	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N77_RS20770	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C7N77_RS20785	COG0477	Major facilitator Superfamily