locus-tag	class	description
NP805_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NP805_RS00010	COG0592	DNA-directed DNA polymerase activity
NP805_RS00035	COG2378	regulation of single-species biofilm formation
NP805_RS00045	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
NP805_RS00050	COG0071	Belongs to the small heat shock protein (HSP20) family
NP805_RS00055	COG0071	Belongs to the small heat shock protein (HSP20) family
NP805_RS00060	COG3977	Valine--pyruvate aminotransferase
NP805_RS00075	COG2814	Major facilitator Superfamily
NP805_RS00080	COG0745	RESPONSE REGULATOR receiver
NP805_RS00085	COG2205	protein histidine kinase activity
NP805_RS00125	COG0653	protein targeting
NP805_RS00165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NP805_RS00170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NP805_RS00170	COG4191	Histidine kinase
NP805_RS00175	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NP805_RS00180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NP805_RS00185	COG1309	transcriptional regulator
NP805_RS00215	COG0561	phosphatase activity
NP805_RS00220	COG2267	carboxylic ester hydrolase activity
NP805_RS00225	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NP805_RS00230	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NP805_RS00235	COG1758	RNA polymerase activity
NP805_RS00240	COG0194	GDP metabolic process
NP805_RS00245	COG0859	PFAM glycosyl transferase family 9
NP805_RS00250	COG3642	lipopolysaccharide core region biosynthetic process
NP805_RS00290	COG0589	response to stress
NP805_RS00295	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NP805_RS00300	COG3706	GGDEF domain
NP805_RS00305	COG1528	Iron-storage protein
NP805_RS00310	COG2081	HI0933 family
NP805_RS00335	COG5433	transposase activity
NP805_RS00340	COG3039	Transposase
NP805_RS00345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NP805_RS00345	COG0784	Response regulator, receiver
NP805_RS00345	COG2205	protein histidine kinase activity
NP805_RS00345	COG2198	Histidine kinase
NP805_RS00355	COG3275	phosphorelay sensor kinase activity
NP805_RS00360	COG3279	Response regulator of the LytR AlgR family
NP805_RS00365	COG2223	nitrite transmembrane transporter activity
NP805_RS00370	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NP805_RS00375	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NP805_RS00390	COG0583	DNA-binding transcription factor activity
NP805_RS00400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NP805_RS00440	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NP805_RS00445	COG2166	iron-sulfur cluster assembly
NP805_RS00450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NP805_RS00455	COG0210	DNA helicase
NP805_RS00470	COG1063	alcohol dehydrogenase
NP805_RS00485	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NP805_RS00490	COG0438	transferase activity, transferring glycosyl groups
NP805_RS00520	COG3550	peptidyl-serine autophosphorylation
NP805_RS00545	COG0653	protein targeting
NP805_RS00555	COG1561	YicC-like family, N-terminal region
NP805_RS00565	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NP805_RS00580	COG2203	Gaf domain
NP805_RS00580	COG4251	negative regulation of phosphorylation
NP805_RS00580	COG5001	Diguanylate cyclase
NP805_RS00580	COG3706	GGDEF domain
NP805_RS00585	COG3084	Protein conserved in bacteria
NP805_RS00595	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
NP805_RS00600	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NP805_RS00605	COG3639	organic phosphonate transmembrane transporter activity
NP805_RS00610	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NP805_RS00615	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NP805_RS00625	COG1335	isochorismatase
NP805_RS00640	COG0204	Acyl-transferase
NP805_RS00645	COG0606	chelatase, subunit chli
NP805_RS00655	COG3978	acetolactate synthase activity
NP805_RS00665	COG0129	dihydroxy-acid dehydratase activity
NP805_RS00685	COG1309	transcriptional regulator
NP805_RS00695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NP805_RS00700	COG0254	rRNA binding
NP805_RS00705	COG0702	epimerase
NP805_RS00710	COG0281	malic enzyme
NP805_RS00720	COG2205	protein histidine kinase activity
NP805_RS00725	COG0745	RESPONSE REGULATOR receiver
NP805_RS00730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NP805_RS00760	COG4310	Domain of unknown function (DUF2172)
NP805_RS00785	COG2089	acid synthase
NP805_RS00795	COG1083	cytidylyl-transferase
NP805_RS00815	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS00820	COG0318	PFAM AMP-dependent synthetase and ligase
NP805_RS00835	COG1215	transferase activity, transferring glycosyl groups
NP805_RS00865	COG0367	asparagine synthase
NP805_RS00870	COG3039	Transposase
NP805_RS00890	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NP805_RS00895	COG1086	Polysaccharide biosynthesis protein
NP805_RS00900	COG0366	Alpha amylase catalytic
NP805_RS00915	COG0443	Heat shock 70 kDa protein
NP805_RS00920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NP805_RS00925	COG3045	CreA protein
NP805_RS00940	COG3039	Transposase
NP805_RS00945	COG0174	glutamine synthetase
NP805_RS00965	COG3842	ATPase activity
NP805_RS00970	COG1176	ABC-type spermidine putrescine transport system, permease component I
NP805_RS00975	COG1177	transmembrane transport
NP805_RS00980	COG2258	MOSC domain
NP805_RS00995	COG2050	protein possibly involved in aromatic compounds catabolism
NP805_RS01000	COG0514	ATP-dependent DNA helicase (RecQ)
NP805_RS01010	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
NP805_RS01020	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
NP805_RS01025	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NP805_RS01035	COG2239	Acts as a magnesium transporter
NP805_RS01040	COG1648	precorrin-2 dehydrogenase activity
NP805_RS01040	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NP805_RS01045	COG2116	formate transmembrane transporter activity
NP805_RS01060	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NP805_RS01075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
NP805_RS01080	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
NP805_RS01090	COG0018	arginyl-trna synthetase
NP805_RS01100	COG1595	DNA-templated transcription, initiation
NP805_RS01115	COG1968	undecaprenyl-diphosphatase activity
NP805_RS01120	COG0667	Aldo Keto reductase
NP805_RS01125	COG2017	converts alpha-aldose to the beta-anomer
NP805_RS01130	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NP805_RS01140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NP805_RS01145	COG1609	Transcriptional regulator
NP805_RS01150	COG3250	beta-galactosidase activity
NP805_RS01165	COG4211	Belongs to the binding-protein-dependent transport system permease family
NP805_RS01200	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NP805_RS01205	COG1288	antiporter activity
NP805_RS01210	COG1438	arginine binding
NP805_RS01215	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
NP805_RS01220	COG0540	Belongs to the ATCase OTCase family
NP805_RS01235	COG0688	phosphatidylethanolamine metabolic process
NP805_RS01245	COG3040	lipid binding
NP805_RS01250	COG2207	Transcriptional regulator
NP805_RS01255	COG1979	alcohol dehydrogenase
NP805_RS01260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NP805_RS01265	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
NP805_RS01275	COG2964	Protein conserved in bacteria
NP805_RS01280	COG3681	Belongs to the UPF0597 family
NP805_RS01290	COG0446	pyridine nucleotide-disulphide oxidoreductase
NP805_RS01295	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NP805_RS01300	COG0564	pseudouridine synthase activity
NP805_RS01310	COG0542	response to heat
NP805_RS01315	COG2502	aspartate--ammonia ligase
NP805_RS01320	COG1522	sequence-specific DNA binding
NP805_RS01330	COG5413	integral membrane protein
NP805_RS01335	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NP805_RS01335	COG0517	IMP dehydrogenase activity
NP805_RS01335	COG0617	tRNA 3'-terminal CCA addition
NP805_RS01340	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS01355	COG2205	protein histidine kinase activity
NP805_RS01365	COG2204	response regulator
NP805_RS01375	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
NP805_RS01380	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
NP805_RS01410	COG0243	molybdopterin cofactor binding
NP805_RS01415	COG3005	denitrification pathway
NP805_RS01425	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NP805_RS01430	COG0569	domain protein
NP805_RS01435	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NP805_RS01460	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NP805_RS01475	COG0250	Participates in transcription elongation, termination and antitermination
NP805_RS01480	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NP805_RS01485	COG0081	regulation of translation
NP805_RS01490	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NP805_RS01495	COG0222	ribosome binding
NP805_RS01500	COG0085	RNA polymerase activity
NP805_RS01505	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NP805_RS01510	COG2964	Protein conserved in bacteria
NP805_RS01525	COG2923	Belongs to the DsrF TusC family
NP805_RS01530	COG2168	tRNA wobble position uridine thiolation
NP805_RS01535	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NP805_RS01540	COG0049	tRNA binding
NP805_RS01545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NP805_RS01550	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NP805_RS01555	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NP805_RS01605	COG2249	NAD(P)H dehydrogenase (quinone) activity
NP805_RS01620	COG1770	oligopeptidase
NP805_RS01640	COG3714	YhhN family
NP805_RS01665	COG1301	dicarboxylic acid transport
NP805_RS01675	COG2095	MarC family integral membrane protein
NP805_RS01685	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NP805_RS01695	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NP805_RS01705	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NP805_RS01730	COG0742	ribosomal rna small subunit methyltransferase
NP805_RS01735	COG0552	protein localization to endoplasmic reticulum
NP805_RS01740	COG2884	Cell division ATP-binding protein ftsE
NP805_RS01745	COG2177	Part of the ABC transporter FtsEX involved in
NP805_RS01755	COG0288	reversible hydration of carbon dioxide
NP805_RS01760	COG2188	Transcriptional regulator
NP805_RS01765	COG1228	amidohydrolase
NP805_RS01770	COG0010	Belongs to the arginase family
NP805_RS01775	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
NP805_RS01780	COG2986	histidine ammonia-lyase
NP805_RS01800	COG2264	protein methyltransferase activity
NP805_RS01805	COG2199	diguanylate cyclase activity
NP805_RS01805	COG2200	EAL domain
NP805_RS01850	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NP805_RS01855	COG1459	type II secretion system
NP805_RS01880	COG4968	Prepilin-type N-terminal cleavage methylation domain
NP805_RS01905	COG1077	Cell shape determining protein MreB Mrl
NP805_RS01910	COG1792	Involved in formation and maintenance of cell shape
NP805_RS01915	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
NP805_RS01920	COG0424	maF-like protein
NP805_RS01925	COG1530	ribonuclease E activity
NP805_RS01930	COG3164	Protein of unknown function
NP805_RS01940	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NP805_RS01945	COG0312	modulator of DNA gyrase
NP805_RS01960	COG0477	Major facilitator Superfamily
NP805_RS01970	COG3437	response regulator, receiver
NP805_RS01975	COG0784	Response regulator, receiver
NP805_RS01975	COG2205	protein histidine kinase activity
NP805_RS01975	COG5002	protein histidine kinase activity
NP805_RS01980	COG2172	sigma factor antagonist activity
NP805_RS01985	COG1366	Belongs to the anti-sigma-factor antagonist family
NP805_RS01995	COG3700	Belongs to the class B bacterial acid phosphatase family
NP805_RS02005	COG1639	'signal transduction protein
NP805_RS02030	COG0189	ligase activity
NP805_RS02035	COG0642	Histidine kinase
NP805_RS02040	COG0745	RESPONSE REGULATOR receiver
NP805_RS02060	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NP805_RS02065	COG0352	thiamine-phosphate diphosphorylase activity
NP805_RS02070	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NP805_RS02080	COG2022	thiamine diphosphate biosynthetic process
NP805_RS02095	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NP805_RS02100	COG0110	maltose O-acetyltransferase activity
NP805_RS02105	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
NP805_RS02120	COG3039	Transposase
NP805_RS02125	COG0814	amino acid
NP805_RS02130	COG3932	Exopolysaccharide synthesis, ExoD
NP805_RS02145	COG1733	regulation of RNA biosynthetic process
NP805_RS02185	COG1494	fructose-1,6-bisphosphatase
NP805_RS02200	COG2959	enzyme of heme biosynthesis
NP805_RS02210	COG0181	hydroxymethylbilane synthase activity
NP805_RS02215	COG3072	Adenylate cyclase
NP805_RS02220	COG0400	carboxylic ester hydrolase activity
NP805_RS02225	COG1965	Belongs to the frataxin family
NP805_RS02235	COG0019	diaminopimelate decarboxylase activity
NP805_RS02240	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NP805_RS02255	COG1011	Hydrolase
NP805_RS02265	COG0668	transmembrane transport
NP805_RS02275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NP805_RS02295	COG0697	spore germination
NP805_RS02370	COG1484	DNA-dependent DNA replication
NP805_RS02375	COG4584	PFAM Integrase catalytic
NP805_RS02395	COG2195	Cleaves the N-terminal amino acid of tripeptides
NP805_RS02400	COG0700	Nucleoside recognition
NP805_RS02405	COG3366	ferrous iron transmembrane transporter activity
NP805_RS02430	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NP805_RS02485	COG1660	Displays ATPase and GTPase activities
NP805_RS02540	COG4644	lycopene metabolic process
NP805_RS02595	COG1695	Transcriptional regulator
NP805_RS02620	COG3173	Aminoglycoside phosphotransferase
NP805_RS02660	COG0561	phosphatase activity
NP805_RS02675	COG0842	Transport permease protein
NP805_RS02675	COG1129	ABC transporter
NP805_RS02685	COG1058	Belongs to the CinA family
NP805_RS02685	COG1546	Belongs to the CinA family
NP805_RS02695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NP805_RS02705	COG1522	sequence-specific DNA binding
NP805_RS02710	COG1368	sulfuric ester hydrolase activity
NP805_RS02730	COG1285	pathogenesis
NP805_RS02750	COG4221	oxidoreductase activity
NP805_RS02780	COG2873	o-acetylhomoserine
NP805_RS02795	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
NP805_RS02815	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
NP805_RS02825	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NP805_RS02830	COG2949	membrane
NP805_RS02835	COG3291	Pkd domain containing protein
NP805_RS02845	COG3039	Transposase
NP805_RS02860	COG0318	PFAM AMP-dependent synthetase and ligase
NP805_RS02870	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NP805_RS02875	COG0596	Alpha beta hydrolase
NP805_RS02880	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NP805_RS02885	COG1169	isochorismate synthase
NP805_RS02890	COG1575	Belongs to the MenA family. Type 1 subfamily
NP805_RS02915	COG0513	Belongs to the DEAD box helicase family
NP805_RS02920	COG1988	membrane-bound metal-dependent
NP805_RS02935	COG1671	Belongs to the UPF0178 family
NP805_RS02955	COG0484	heat shock protein binding
NP805_RS02960	COG3263	regulation of cellular component size
NP805_RS02965	COG3722	fumarate hydratase activity
NP805_RS02970	COG0246	Mannitol dehydrogenase
NP805_RS02975	COG2213	PTS system mannitol-specific
NP805_RS02975	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS02995	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
NP805_RS03005	COG3385	transposase activity
NP805_RS03020	COG2771	luxR family
NP805_RS03045	COG3133	Outer membrane lipoprotein
NP805_RS03050	COG0456	acetyltransferase
NP805_RS03070	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
NP805_RS03075	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NP805_RS03095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
NP805_RS03100	COG1459	type II secretion system
NP805_RS03105	COG2165	general secretion pathway protein
NP805_RS03115	COG2165	general secretion pathway protein
NP805_RS03120	COG4795	General secretion pathway protein
NP805_RS03140	COG3156	type II secretion system protein K
NP805_RS03150	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
NP805_RS03165	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NP805_RS03170	COG1011	Hydrolase
NP805_RS03175	COG0494	nUDIX hydrolase
NP805_RS03180	COG1218	3'(2'),5'-bisphosphate nucleotidase
NP805_RS03185	COG0814	amino acid
NP805_RS03190	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NP805_RS03195	COG3708	Transcriptional regulator
NP805_RS03195	COG2207	Transcriptional regulator
NP805_RS03205	COG0626	cystathionine gamma-synthase activity
NP805_RS03210	COG0460	homoserine dehydrogenase
NP805_RS03210	COG0527	aspartate kinase activity
NP805_RS03225	COG1346	cytolysis
NP805_RS03230	COG1380	Effector of murein hydrolase LrgA
NP805_RS03235	COG0583	DNA-binding transcription factor activity
NP805_RS03270	COG0589	response to stress
NP805_RS03275	COG0659	secondary active sulfate transmembrane transporter activity
NP805_RS03280	COG1546	Belongs to the CinA family
NP805_RS03285	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NP805_RS03295	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NP805_RS03300	COG0527	aspartate kinase activity
NP805_RS03305	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NP805_RS03340	COG1686	Belongs to the peptidase S11 family
NP805_RS03345	COG0586	Pfam SNARE associated Golgi protein
NP805_RS03350	COG1253	flavin adenine dinucleotide binding
NP805_RS03365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NP805_RS03370	COG0795	lipopolysaccharide-transporting ATPase activity
NP805_RS03375	COG0795	lipopolysaccharide-transporting ATPase activity
NP805_RS03390	COG0582	viral genome integration into host DNA
NP805_RS03405	COG3561	AntA/AntB antirepressor
NP805_RS03460	COG3436	PFAM IS66 Orf2 family protein
NP805_RS03465	COG4372	Transposase
NP805_RS03475	COG0004	ammonium transporteR
NP805_RS03480	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NP805_RS03495	COG2165	general secretion pathway protein
NP805_RS03500	COG0084	hydrolase, TatD family'
NP805_RS03505	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NP805_RS03515	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NP805_RS03520	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
NP805_RS03525	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NP805_RS03530	COG0813	purine-nucleoside phosphorylase activity
NP805_RS03540	COG0560	Phosphoserine phosphatase
NP805_RS03565	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
NP805_RS03570	COG0776	regulation of translation
NP805_RS03585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NP805_RS03590	COG0735	belongs to the Fur family
NP805_RS03610	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
NP805_RS03615	COG0513	Belongs to the DEAD box helicase family
NP805_RS03620	COG3022	response to hydroperoxide
NP805_RS03635	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NP805_RS03640	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NP805_RS03645	COG0762	integral membrane protein
NP805_RS03650	COG1872	DUF167
NP805_RS03665	COG4166	transmembrane transport
NP805_RS03675	COG0110	maltose O-acetyltransferase activity
NP805_RS03685	COG1024	Enoyl-CoA hydratase
NP805_RS03700	COG4221	oxidoreductase activity
NP805_RS03710	COG2957	Belongs to the agmatine deiminase family
NP805_RS03715	COG0154	amidase activity
NP805_RS03735	COG0513	Belongs to the DEAD box helicase family
NP805_RS03755	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
NP805_RS03760	COG3385	transposase activity
NP805_RS03820	COG2816	NAD+ diphosphatase activity
NP805_RS03825	COG2205	protein histidine kinase activity
NP805_RS03830	COG0745	RESPONSE REGULATOR receiver
NP805_RS03835	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NP805_RS03840	COG1136	(ABC) transporter
NP805_RS03840	COG0577	efflux transmembrane transporter activity
NP805_RS03845	COG1505	serine-type exopeptidase activity
NP805_RS03850	COG2982	Protein involved in outer membrane biogenesis
NP805_RS03860	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS03865	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NP805_RS03870	COG3730	PTS system glucitol sorbitol-specific
NP805_RS03895	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS03905	COG1349	DNA-binding transcription factor activity
NP805_RS03910	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NP805_RS03930	COG2130	NADP-dependent
NP805_RS03935	COG1764	response to oxidative stress
NP805_RS03940	COG1846	Transcriptional regulator
NP805_RS03990	COG0733	neurotransmitter:sodium symporter activity
NP805_RS04010	COG0733	neurotransmitter:sodium symporter activity
NP805_RS04035	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NP805_RS04050	COG1794	racemase activity, acting on amino acids and derivatives
NP805_RS04060	COG2731	YhcH YjgK YiaL family protein
NP805_RS04070	COG0668	transmembrane transport
NP805_RS04075	COG1376	ErfK ybiS ycfS ynhG family protein
NP805_RS04080	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NP805_RS04090	COG0789	Transcriptional regulator
NP805_RS04130	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
NP805_RS04140	COG0488	(ABC) transporter
NP805_RS04145	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NP805_RS04145	COG0517	IMP dehydrogenase activity
NP805_RS04155	COG0330	HflC and HflK could
NP805_RS04160	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
NP805_RS04160	COG1648	precorrin-2 dehydrogenase activity
NP805_RS04165	COG0175	sulfate reduction
NP805_RS04170	COG2895	sulfate adenylyltransferase (ATP) activity
NP805_RS04175	COG0471	metal ion transport
NP805_RS04175	COG3273	potassium ion transport
NP805_RS04180	COG0529	Catalyzes the synthesis of activated sulfate
NP805_RS04185	COG1278	Cold shock
NP805_RS04200	COG5433	transposase activity
NP805_RS04210	COG0840	transmembrane signaling receptor activity
NP805_RS04230	COG1136	(ABC) transporter
NP805_RS04245	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
NP805_RS04260	COG1940	carbohydrate kinase activity
NP805_RS04265	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NP805_RS04270	COG0126	phosphoglycerate kinase activity
NP805_RS04275	COG0191	fructose-bisphosphate aldolase activity
NP805_RS04280	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NP805_RS04335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NP805_RS04340	COG1595	DNA-templated transcription, initiation
NP805_RS04345	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
NP805_RS04360	COG0481	GTPase activity
NP805_RS04370	COG0571	ribonuclease III activity
NP805_RS04380	COG1381	Involved in DNA repair and RecF pathway recombination
NP805_RS04385	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
NP805_RS04390	COG3023	N-Acetylmuramoyl-L-alanine amidase
NP805_RS04395	COG4807	Protein conserved in bacteria
NP805_RS04405	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NP805_RS04410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NP805_RS04415	COG3956	TIGRFAM MazG family protein
NP805_RS04420	COG0504	CTP synthase activity
NP805_RS04425	COG0148	phosphopyruvate hydratase activity
NP805_RS04430	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
NP805_RS04435	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NP805_RS04445	COG0585	pseudouridine synthase activity
NP805_RS04450	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
NP805_RS04455	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
NP805_RS04460	COG1238	metal cluster binding
NP805_RS04465	COG1388	LysM domain
NP805_RS04465	COG4942	peptidase
NP805_RS04475	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NP805_RS04480	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NP805_RS04485	COG1610	YqeY-like protein
NP805_RS04490	COG0358	DNA primase activity
NP805_RS04495	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NP805_RS04530	COG0582	viral genome integration into host DNA
NP805_RS04565	COG0151	Belongs to the GarS family
NP805_RS04570	COG0138	bifunctional purine biosynthesis protein purh
NP805_RS04580	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NP805_RS04585	COG3036	rescue of stalled ribosome
NP805_RS04590	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NP805_RS04595	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NP805_RS04605	COG0673	inositol 2-dehydrogenase activity
NP805_RS04620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NP805_RS04625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NP805_RS04630	COG3227	Zinc metalloprotease (Elastase)
NP805_RS04640	COG0477	Major facilitator Superfamily
NP805_RS04650	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NP805_RS04655	COG1027	Aspartate ammonia-lyase
NP805_RS04660	COG3030	protein affecting phage T7 exclusion by the F plasmid
NP805_RS04665	COG0534	Mate efflux family protein
NP805_RS04670	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NP805_RS04675	COG0459	protein refolding
NP805_RS04685	COG3300	MHYT domain
NP805_RS04685	COG5001	Diguanylate cyclase
NP805_RS04695	COG0564	pseudouridine synthase activity
NP805_RS04700	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NP805_RS04730	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NP805_RS04740	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
NP805_RS04745	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
NP805_RS04750	COG1178	ABC-type Fe3 transport system permease component
NP805_RS04755	COG4143	(ABC) transporter
NP805_RS04770	COG0066	3-isopropylmalate dehydratase activity
NP805_RS04775	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NP805_RS04780	COG0473	3-isopropylmalate dehydrogenase activity
NP805_RS04785	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NP805_RS04795	COG0671	phosphoesterase, PA-phosphatase related
NP805_RS04810	COG0028	Belongs to the TPP enzyme family
NP805_RS04815	COG0440	acetolactate synthase activity
NP805_RS04820	COG0280	phosphate acetyltransferase
NP805_RS04820	COG0857	belongs to the CobB CobQ family
NP805_RS04825	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NP805_RS04835	COG3013	Belongs to the UPF0304 family
NP805_RS04840	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
NP805_RS04845	COG2716	regulation of RNA biosynthetic process
NP805_RS04855	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
NP805_RS04860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NP805_RS04895	COG2198	Histidine kinase
NP805_RS04895	COG5002	protein histidine kinase activity
NP805_RS04895	COG0784	Response regulator, receiver
NP805_RS04920	COG0840	transmembrane signaling receptor activity
NP805_RS04930	COG1464	Belongs to the NlpA lipoprotein family
NP805_RS04935	COG2011	ABC-type metal ion transport system permease component
NP805_RS04960	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NP805_RS04960	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NP805_RS04965	COG0802	atpase or kinase
NP805_RS04975	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NP805_RS04980	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NP805_RS04985	COG1923	regulation of RNA biosynthetic process
NP805_RS04990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NP805_RS04995	COG0330	HflC and HflK could
NP805_RS05000	COG0330	HflC and HflK could
NP805_RS05005	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
NP805_RS05010	COG0142	geranyltranstransferase activity
NP805_RS05015	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NP805_RS05020	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NP805_RS05025	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NP805_RS05030	COG3314	Sporulation integral membrane protein YlbJ
NP805_RS05035	COG0318	PFAM AMP-dependent synthetase and ligase
NP805_RS05065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NP805_RS05085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NP805_RS05090	COG2967	ApaG domain
NP805_RS05095	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NP805_RS05100	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
NP805_RS05110	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
NP805_RS05115	COG3178	'Phosphotransferase
NP805_RS05120	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NP805_RS05125	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NP805_RS05130	COG2252	PERMEase
NP805_RS05140	COG0488	(ABC) transporter
NP805_RS05145	COG0741	lytic transglycosylase activity
NP805_RS05165	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP805_RS05175	COG3721	Heme iron utilization protein
NP805_RS05180	COG0748	coenzyme F420 binding
NP805_RS05205	COG4771	TonB-dependent receptor
NP805_RS05210	COG2814	Major facilitator Superfamily
NP805_RS05220	COG3655	Transcriptional regulator
NP805_RS05230	COG2205	protein histidine kinase activity
NP805_RS05230	COG2202	Pas domain
NP805_RS05245	COG3397	chitin binding
NP805_RS05250	COG3385	transposase activity
NP805_RS05255	COG2226	methyltransferase
NP805_RS05265	COG1765	OsmC-like protein
NP805_RS05280	COG3954	Phosphoribulokinase
NP805_RS05290	COG3089	Belongs to the UPF0270 family
NP805_RS05295	COG3706	GGDEF domain
NP805_RS05295	COG4251	negative regulation of phosphorylation
NP805_RS05295	COG5001	Diguanylate cyclase
NP805_RS05295	COG2203	Gaf domain
NP805_RS05300	COG0429	hydrolase of the alpha beta-hydrolase fold
NP805_RS05305	COG0784	Response regulator, receiver
NP805_RS05305	COG0835	chemotaxis
NP805_RS05315	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
NP805_RS05320	COG1047	Peptidyl-prolyl cis-trans
NP805_RS05335	COG0545	Peptidyl-prolyl cis-trans isomerase
NP805_RS05340	COG2204	response regulator
NP805_RS05360	COG0737	Belongs to the 5'-nucleotidase family
NP805_RS05365	COG2200	EAL domain
NP805_RS05380	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NP805_RS05385	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NP805_RS05390	COG0826	peptidase U32
NP805_RS05400	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NP805_RS05405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NP805_RS05415	COG3039	Transposase
NP805_RS05440	COG3039	Transposase
NP805_RS05445	COG2197	response regulator
NP805_RS05475	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NP805_RS05480	COG2201	protein-glutamate methylesterase activity
NP805_RS05485	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NP805_RS05510	COG0840	transmembrane signaling receptor activity
NP805_RS05515	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NP805_RS05525	COG1280	lysine exporter protein (LysE YggA)
NP805_RS05530	COG0826	peptidase U32
NP805_RS05550	COG3813	Protein conserved in bacteria
NP805_RS05560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NP805_RS05575	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
NP805_RS05600	COG0300	oxidoreductase activity
NP805_RS05620	COG2610	gluconate transmembrane transporter activity
NP805_RS05625	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
NP805_RS05630	COG3622	Belongs to the hyi family
NP805_RS05635	COG0235	Class ii aldolase
NP805_RS05645	COG2084	Dehydrogenase
NP805_RS05650	COG1349	DNA-binding transcription factor activity
NP805_RS05700	COG1605	Chorismate mutase
NP805_RS05700	COG0077	Prephenate dehydratase
NP805_RS05730	COG3272	Protein of unknown function (DUF1722)
NP805_RS05735	COG0789	Transcriptional regulator
NP805_RS05740	COG0415	Belongs to the DNA photolyase family
NP805_RS05750	COG0300	oxidoreductase activity
NP805_RS05765	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NP805_RS05790	COG0783	Belongs to the Dps family
NP805_RS05795	COG1151	hydroxylamine reductase activity
NP805_RS05805	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NP805_RS05810	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NP805_RS05810	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NP805_RS05820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NP805_RS05900	COG2003	Belongs to the UPF0758 family
NP805_RS05940	COG3039	Transposase
NP805_RS05955	COG4983	Phage plasmid primase, P4 family domain protein
NP805_RS05965	COG2916	Histone family protein nucleoid-structuring protein H-NS
NP805_RS05990	COG0582	viral genome integration into host DNA
NP805_RS05995	COG3459	Glycosyltransferase 36 associated
NP805_RS06020	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NP805_RS06025	COG1666	GTP binding
NP805_RS06035	COG2211	Major facilitator Superfamily
NP805_RS06045	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NP805_RS06055	COG2813	Specifically methylates the guanine in position
NP805_RS06060	COG0271	Belongs to the BolA IbaG family
NP805_RS06070	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NP805_RS06075	COG1805	sodium ion transport
NP805_RS06080	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NP805_RS06085	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NP805_RS06090	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
NP805_RS06095	COG2871	sodium ion transport
NP805_RS06100	COG1477	protein flavinylation
NP805_RS06115	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NP805_RS06120	COG0840	transmembrane signaling receptor activity
NP805_RS06125	COG0583	DNA-binding transcription factor activity
NP805_RS06135	COG2363	Small membrane protein
NP805_RS06140	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
NP805_RS06150	COG0473	3-isopropylmalate dehydrogenase activity
NP805_RS06155	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NP805_RS06160	COG1611	Belongs to the LOG family
NP805_RS06175	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NP805_RS06175	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
NP805_RS06185	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
NP805_RS06210	COG3098	single-species biofilm formation
NP805_RS06215	COG0564	pseudouridine synthase activity
NP805_RS06225	COG4580	involved in the transport of maltose and maltodextrins
NP805_RS06235	COG5433	transposase activity
NP805_RS06240	COG1263	PTS System
NP805_RS06240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NP805_RS06250	COG2171	N-acyltransferase activity
NP805_RS06255	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NP805_RS06260	COG0024	Methionine aminopeptidase
NP805_RS06265	COG0052	Belongs to the universal ribosomal protein uS2 family
NP805_RS06270	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NP805_RS06275	COG0528	UMP kinase activity
NP805_RS06280	COG0233	cytoplasmic translational termination
NP805_RS06285	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NP805_RS06290	COG0575	Belongs to the CDS family
NP805_RS06295	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
NP805_RS06300	COG0750	zinc metalloprotease
NP805_RS06315	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NP805_RS06320	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NP805_RS06325	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NP805_RS06330	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NP805_RS06335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NP805_RS06345	COG0825	malonyl-CoA metabolic process
NP805_RS06350	COG3710	Transcriptional regulator
NP805_RS06355	COG0531	amino acid
NP805_RS06360	COG1982	Orn Lys Arg decarboxylase major
NP805_RS06365	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NP805_RS06380	COG0814	amino acid
NP805_RS06385	COG0531	amino acid
NP805_RS06395	COG0488	(ABC) transporter
NP805_RS06400	COG3385	transposase activity
NP805_RS06410	COG3590	peptidase
NP805_RS06415	COG0037	tRNA processing
NP805_RS06480	COG0366	Alpha amylase catalytic
NP805_RS06490	COG1881	PFAM PEBP family protein
NP805_RS06495	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NP805_RS06500	COG0583	DNA-binding transcription factor activity
NP805_RS06510	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NP805_RS06520	COG0583	DNA-binding transcription factor activity
NP805_RS06525	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS06530	COG0616	signal peptide processing
NP805_RS06535	COG3724	N-succinylarginine dihydrolase activity
NP805_RS06555	COG0840	transmembrane signaling receptor activity
NP805_RS06565	COG2971	BadF BadG BcrA BcrD
NP805_RS06575	COG4608	Belongs to the ABC transporter superfamily
NP805_RS06580	COG0444	Belongs to the ABC transporter superfamily
NP805_RS06585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NP805_RS06600	COG2205	protein histidine kinase activity
NP805_RS06600	COG0784	Response regulator, receiver
NP805_RS06640	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NP805_RS06645	COG1289	transmembrane transporter activity
NP805_RS06650	COG0303	'Molybdopterin
NP805_RS06665	COG4662	Binding-protein-dependent transport system inner membrane component
NP805_RS06675	COG2204	response regulator
NP805_RS06680	COG3852	Histidine kinase
NP805_RS06690	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NP805_RS06730	COG3383	formate dehydrogenase (NAD+) activity
NP805_RS06735	COG0437	4 iron, 4 sulfur cluster binding
NP805_RS06750	COG0281	malic enzyme
NP805_RS06760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NP805_RS06775	COG2706	6-phosphogluconolactonase activity
NP805_RS06780	COG1196	nuclear chromosome segregation
NP805_RS06780	COG3264	Mechanosensitive ion channel
NP805_RS06785	COG0469	pyruvate kinase activity
NP805_RS06800	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NP805_RS06800	COG4651	solute:proton antiporter activity
NP805_RS06805	COG0405	Gamma-glutamyltransferase
NP805_RS06810	COG2974	May be involved in recombination
NP805_RS06820	COG0420	3'-5' exonuclease activity
NP805_RS06825	COG0419	ATPase involved in DNA repair
NP805_RS06835	COG3038	cytochrome b561
NP805_RS06845	COG3706	GGDEF domain
NP805_RS06850	COG2190	(PTS) system
NP805_RS06860	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS06865	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
NP805_RS06885	COG1720	tRNA m6t6A37 methyltransferase activity
NP805_RS06905	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NP805_RS06910	COG4988	ABC transporter
NP805_RS06930	COG0745	RESPONSE REGULATOR receiver
NP805_RS06940	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
NP805_RS06955	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
NP805_RS06960	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
NP805_RS06970	COG0083	homoserine kinase activity
NP805_RS06975	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
NP805_RS06980	COG3039	Transposase
NP805_RS07000	COG3384	dioxygenase
NP805_RS07010	COG1283	sodium-dependent phosphate transmembrane transporter activity
NP805_RS07015	COG0531	amino acid
NP805_RS07020	COG0531	amino acid
NP805_RS07035	COG1396	sequence-specific DNA binding
NP805_RS07035	COG1917	Cupin 2, conserved barrel domain protein
NP805_RS07040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NP805_RS07075	COG5433	transposase activity
NP805_RS07085	COG2916	Histone family protein nucleoid-structuring protein H-NS
NP805_RS07090	COG5433	transposase activity
NP805_RS07095	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NP805_RS07100	COG2375	cellular response to nickel ion
NP805_RS07110	COG0577	efflux transmembrane transporter activity
NP805_RS07110	COG1136	(ABC) transporter
NP805_RS07115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NP805_RS07125	COG1227	inorganic diphosphatase activity
NP805_RS07135	COG0497	DNA recombination
NP805_RS07140	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NP805_RS07145	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NP805_RS07150	COG0443	Heat shock 70 kDa protein
NP805_RS07155	COG0484	heat shock protein binding
NP805_RS07185	COG1285	pathogenesis
NP805_RS07230	COG0095	Lipoate-protein ligase
NP805_RS07240	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NP805_RS07245	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NP805_RS07270	COG0708	Exodeoxyribonuclease III
NP805_RS07290	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
NP805_RS07325	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
NP805_RS07330	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
NP805_RS07335	COG1845	cytochrome c oxidase, subunit III
NP805_RS07340	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
NP805_RS07345	COG0109	protoheme IX farnesyltransferase activity
NP805_RS07350	COG2814	Major facilitator Superfamily
NP805_RS07370	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP805_RS07385	COG2207	Transcriptional regulator
NP805_RS07390	COG0538	isocitrate dehydrogenase activity
NP805_RS07400	COG3048	D-serine ammonia-lyase activity
NP805_RS07405	COG2610	gluconate transmembrane transporter activity
NP805_RS07410	COG0583	DNA-binding transcription factor activity
NP805_RS07430	COG1484	DNA-dependent DNA replication
NP805_RS07435	COG4584	PFAM Integrase catalytic
NP805_RS07460	COG3039	Transposase
NP805_RS07465	COG2020	methyltransferase activity
NP805_RS07470	COG3039	Transposase
NP805_RS07480	COG5433	transposase activity
NP805_RS07495	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NP805_RS07515	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NP805_RS07520	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NP805_RS07570	COG5642	Protein of unknown function (DUF2384)
NP805_RS07575	COG0582	viral genome integration into host DNA
NP805_RS07585	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
NP805_RS07595	COG2867	negative regulation of translational initiation
NP805_RS07600	COG2914	Belongs to the UPF0125 (RnfH) family
NP805_RS07605	COG0702	epimerase
NP805_RS07610	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NP805_RS07640	COG4964	Belongs to the GSP D family
NP805_RS07650	COG2894	cell division
NP805_RS07690	COG1454	alcohol dehydrogenase
NP805_RS07700	COG0564	pseudouridine synthase activity
NP805_RS07725	COG0840	transmembrane signaling receptor activity
NP805_RS07730	COG1280	lysine exporter protein (LysE YggA)
NP805_RS07750	COG3263	regulation of cellular component size
NP805_RS07760	COG1876	peptidase activity
NP805_RS07765	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NP805_RS07770	COG1393	Belongs to the ArsC family
NP805_RS07775	COG0583	DNA-binding transcription factor activity
NP805_RS07790	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
NP805_RS07795	COG0017	Asparaginyl-tRNA synthetase
NP805_RS07815	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NP805_RS07820	COG0156	8-amino-7-oxononanoate synthase activity
NP805_RS07825	COG2226	methyltransferase
NP805_RS07825	COG1073	alpha beta
NP805_RS07830	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
NP805_RS07835	COG0501	Belongs to the peptidase M48B family
NP805_RS07845	COG3217	Mosc domain protein beta barrel domain protein
NP805_RS07845	COG3217	Mosc domain protein beta barrel domain protein
NP805_RS07845	COG0633	Ferredoxin
NP805_RS07845	COG0633	Ferredoxin
NP805_RS07855	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
NP805_RS07855	COG0674	pyruvate-flavodoxin oxidoreductase activity
NP805_RS07855	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NP805_RS07855	COG1013	pyruvate-flavodoxin oxidoreductase activity
NP805_RS07865	COG2841	Protein conserved in bacteria
NP805_RS07875	COG0534	Mate efflux family protein
NP805_RS07915	COG1309	transcriptional regulator
NP805_RS07930	COG0791	NLP P60 protein
NP805_RS07940	COG0583	DNA-binding transcription factor activity
NP805_RS07945	COG0450	alkyl hydroperoxide reductase
NP805_RS07965	COG0500	methyltransferase
NP805_RS07970	COG4106	trans-aconitate 2-methyltransferase activity
NP805_RS07975	COG1801	Protein of unknown function DUF72
NP805_RS07980	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NP805_RS07985	COG0217	transcriptional regulatory protein
NP805_RS07995	COG1940	carbohydrate kinase activity
NP805_RS07995	COG1846	Transcriptional regulator
NP805_RS08000	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NP805_RS08005	COG0363	glucosamine-6-phosphate deaminase activity
NP805_RS08010	COG1263	PTS System
NP805_RS08010	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NP805_RS08010	COG2190	(PTS) system
NP805_RS08020	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NP805_RS08025	COG0735	belongs to the Fur family
NP805_RS08035	COG0716	FMN binding
NP805_RS08050	COG0596	Alpha beta hydrolase
NP805_RS08055	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
NP805_RS08060	COG0033	Phosphoglucomutase
NP805_RS08070	COG1846	Transcriptional regulator
NP805_RS08075	COG2951	lytic endotransglycosylase activity
NP805_RS08080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NP805_RS08085	COG4136	ATPase activity
NP805_RS08090	COG4135	transport system, permease component
NP805_RS08095	COG4134	Bacterial extracellular solute-binding protein
NP805_RS08100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NP805_RS08105	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
NP805_RS08120	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NP805_RS08135	COG0729	surface antigen
NP805_RS08140	COG2911	Protein conserved in bacteria
NP805_RS08160	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NP805_RS08185	COG1607	acyl-coa hydrolase
NP805_RS08195	COG3021	interspecies interaction between organisms
NP805_RS08200	COG0741	lytic transglycosylase activity
NP805_RS08200	COG1388	LysM domain
NP805_RS08205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NP805_RS08210	COG2226	methyltransferase
NP805_RS08215	COG0328	RNA-DNA hybrid ribonuclease activity
NP805_RS08235	COG0784	Response regulator, receiver
NP805_RS08235	COG3437	response regulator, receiver
NP805_RS08240	COG1960	acyl-CoA dehydrogenase activity
NP805_RS08245	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NP805_RS08250	COG0121	glutamine amidotransferase
NP805_RS08280	COG2197	response regulator
NP805_RS08285	COG3850	Histidine kinase
NP805_RS08290	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
NP805_RS08295	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NP805_RS08305	COG0243	molybdopterin cofactor binding
NP805_RS08310	COG0437	4 iron, 4 sulfur cluster binding
NP805_RS08315	COG0348	domain, Protein
NP805_RS08325	COG3005	denitrification pathway
NP805_RS08330	COG0521	Mo-molybdopterin cofactor biosynthetic process
NP805_RS08335	COG0315	cyclic pyranopterin monophosphate synthase activity
NP805_RS08340	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
NP805_RS08345	COG0314	molybdopterin synthase activity
NP805_RS08360	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
NP805_RS08365	COG0596	Alpha beta hydrolase
NP805_RS08370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NP805_RS08375	COG0303	'Molybdopterin
NP805_RS08380	COG0302	gtp cyclohydrolase
NP805_RS08385	COG0840	transmembrane signaling receptor activity
NP805_RS08390	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NP805_RS08400	COG0583	DNA-binding transcription factor activity
NP805_RS08430	COG2195	Cleaves the N-terminal amino acid of tripeptides
NP805_RS08435	COG1166	arginine decarboxylase activity
NP805_RS08455	COG1061	Type III restriction enzyme res subunit
NP805_RS08465	COG0346	lactoylglutathione lyase activity
NP805_RS08475	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NP805_RS08485	COG1187	pseudouridine synthase activity
NP805_RS08495	COG2807	transmembrane transport
NP805_RS08505	COG0583	DNA-binding transcription factor activity
NP805_RS08525	COG2979	Protein of unknown function (DUF533)
NP805_RS08530	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NP805_RS08540	COG1294	oxidase, subunit
NP805_RS08550	COG2814	Major facilitator Superfamily
NP805_RS08555	COG0656	L-ascorbic acid biosynthetic process
NP805_RS08590	COG0583	DNA-binding transcription factor activity
NP805_RS08595	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NP805_RS08600	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NP805_RS08605	COG2271	Major facilitator Superfamily
NP805_RS08610	COG1349	DNA-binding transcription factor activity
NP805_RS08615	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NP805_RS08620	COG0584	glycerophosphoryl diester phosphodiesterase
NP805_RS08625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NP805_RS08630	COG1605	Chorismate mutase
NP805_RS08630	COG0287	Prephenate dehydrogenase
NP805_RS08635	COG0583	DNA-binding transcription factor activity
NP805_RS08640	COG3085	chromosome segregation
NP805_RS08645	COG4574	serine-type endopeptidase inhibitor activity
NP805_RS08680	COG0675	Transposase, IS605 OrfB family
NP805_RS08690	COG3083	sulfuric ester hydrolase activity
NP805_RS08695	COG3082	Protein of unknown function (DUF1414)
NP805_RS08700	COG3081	Nucleoid-associated protein
NP805_RS08705	COG2182	Extracellular solute-binding protein
NP805_RS08710	COG1175	transmembrane transport
NP805_RS08715	COG3833	ABC-type maltose transport systems, permease component
NP805_RS08720	COG3842	ATPase activity
NP805_RS08740	COG0425	Belongs to the sulfur carrier protein TusA family
NP805_RS08745	COG4783	chaperone-mediated protein folding
NP805_RS08755	COG1393	Belongs to the ArsC family
NP805_RS08765	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
NP805_RS08770	COG2431	L-lysine efflux transmembrane transporter activity
NP805_RS08805	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NP805_RS08815	COG0446	pyridine nucleotide-disulphide oxidoreductase
NP805_RS08820	COG2373	Large extracellular alpha-helical protein
NP805_RS08825	COG4953	penicillin-binding protein 1C
NP805_RS08835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NP805_RS08835	COG0301	tRNA thio-modification
NP805_RS08850	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NP805_RS08885	COG1083	cytidylyl-transferase
NP805_RS08900	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
NP805_RS08905	COG2089	acid synthase
NP805_RS08915	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
NP805_RS08935	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NP805_RS08960	COG0483	inositol monophosphate 1-phosphatase activity
NP805_RS08970	COG0625	glutathione transferase activity
NP805_RS08980	COG0601	transmembrane transport
NP805_RS08985	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NP805_RS08990	COG0444	Belongs to the ABC transporter superfamily
NP805_RS08995	COG2814	Major facilitator Superfamily
NP805_RS09000	COG0583	DNA-binding transcription factor activity
NP805_RS09005	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
NP805_RS09010	COG0243	molybdopterin cofactor binding
NP805_RS09030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NP805_RS09035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NP805_RS09040	COG0404	The glycine cleavage system catalyzes the degradation of glycine
NP805_RS09045	COG0509	glycine decarboxylation via glycine cleavage system
NP805_RS09050	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NP805_RS09050	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
NP805_RS09065	COG3634	alkyl hydroperoxide reductase activity
NP805_RS09075	COG0517	IMP dehydrogenase activity
NP805_RS09080	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NP805_RS09085	COG0343	queuine tRNA-ribosyltransferase activity
NP805_RS09090	COG1862	Preprotein translocase
NP805_RS09095	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NP805_RS09100	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NP805_RS09115	COG0826	peptidase U32
NP805_RS09120	COG0826	peptidase U32
NP805_RS09125	COG3154	lipid carrier protein
NP805_RS09145	COG1104	cysteine desulfurase activity
NP805_RS09150	COG0822	iron-sulfur transferase activity
NP805_RS09160	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
NP805_RS09165	COG0443	Heat shock 70 kDa protein
NP805_RS09170	COG0633	Ferredoxin
NP805_RS09180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NP805_RS09185	COG0105	UTP biosynthetic process
NP805_RS09190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NP805_RS09210	COG0124	histidyl-tRNA synthetase
NP805_RS09215	COG2976	Protein conserved in bacteria
NP805_RS09220	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NP805_RS09225	COG1160	GTP binding
NP805_RS09230	COG1645	bacterial-type flagellum-dependent swarming motility
NP805_RS09240	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NP805_RS09245	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NP805_RS09245	COG0047	phosphoribosylformylglycinamidine synthase activity
NP805_RS09255	COG2354	Protein conserved in bacteria
NP805_RS09270	COG3150	esterase
NP805_RS09275	COG1252	NADH dehydrogenase
NP805_RS09280	COG0393	Putative heavy-metal-binding
NP805_RS09290	COG1619	proteins homologs of microcin C7 resistance protein MccF
NP805_RS09295	COG1368	sulfuric ester hydrolase activity
NP805_RS09305	COG0527	aspartate kinase activity
NP805_RS09310	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
NP805_RS09310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NP805_RS09315	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NP805_RS09335	COG0596	Alpha beta hydrolase
NP805_RS09345	COG1285	pathogenesis
NP805_RS09360	COG0577	efflux transmembrane transporter activity
NP805_RS09365	COG1136	(ABC) transporter
NP805_RS09380	COG2814	Major facilitator Superfamily
NP805_RS09405	COG0672	)-iron permease
NP805_RS09440	COG0659	secondary active sulfate transmembrane transporter activity
NP805_RS09535	COG3829	transcription factor binding
NP805_RS09575	COG3039	Transposase
NP805_RS09620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NP805_RS09625	COG1278	Cold shock
NP805_RS09630	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NP805_RS09635	COG0542	response to heat
NP805_RS09640	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NP805_RS09645	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
NP805_RS09650	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
NP805_RS09655	COG3134	Outer membrane lipoprotein
NP805_RS09660	COG3706	GGDEF domain
NP805_RS09665	COG0492	ferredoxin-NADP+ reductase activity
NP805_RS09680	COG0531	amino acid
NP805_RS09680	COG1674	ftsk spoiiie
NP805_RS09685	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
NP805_RS09690	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NP805_RS09695	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NP805_RS09700	COG1286	toxin biosynthetic process
NP805_RS09705	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NP805_RS09715	COG4172	Belongs to the ABC transporter superfamily
NP805_RS09720	COG4172	Belongs to the ABC transporter superfamily
NP805_RS09725	COG4171	peptide transport system, permease
NP805_RS09730	COG4168	peptide transport system, permease
NP805_RS09740	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
NP805_RS09745	COG1842	Phage shock protein A
NP805_RS09760	COG3106	COG3106 Predicted ATPase
NP805_RS09765	COG3768	UPF0283 membrane protein
NP805_RS09775	COG2154	pterin-4-alpha-carbinolamine dehydratase
NP805_RS09790	COG2199	diguanylate cyclase activity
NP805_RS09810	COG1022	Amp-dependent synthetase and ligase
NP805_RS09815	COG0295	cytidine deaminase activity
NP805_RS09820	COG1346	cytolysis
NP805_RS09825	COG1380	Effector of murein hydrolase LrgA
NP805_RS09835	COG3345	alpha-galactosidase
NP805_RS09845	COG2925	Exonuclease
NP805_RS09850	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
NP805_RS09860	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NP805_RS09865	COG0436	Aminotransferase
NP805_RS09875	COG2160	L-arabinose isomerase activity
NP805_RS09885	COG1069	ribulokinase activity
NP805_RS09890	COG1879	ABC-type sugar transport system periplasmic component
NP805_RS09895	COG1129	ABC transporter
NP805_RS09900	COG1172	Belongs to the binding-protein-dependent transport system permease family
NP805_RS09910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NP805_RS09915	COG1085	galactose-1-phosphate uridylyltransferase
NP805_RS09920	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NP805_RS09925	COG1609	Transcriptional regulator
NP805_RS09930	COG4580	involved in the transport of maltose and maltodextrins
NP805_RS09960	COG2182	Extracellular solute-binding protein
NP805_RS09965	COG1175	transmembrane transport
NP805_RS09970	COG3833	ABC-type maltose transport systems, permease component
NP805_RS09975	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NP805_RS09980	COG1874	Beta-galactosidase
NP805_RS09990	COG0469	pyruvate kinase activity
NP805_RS09995	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NP805_RS10000	COG0254	rRNA binding
NP805_RS10015	COG1451	nucleotide metabolic process
NP805_RS10030	COG3069	C4-dicarboxylate transmembrane transporter activity
NP805_RS10040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NP805_RS10040	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
NP805_RS10045	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NP805_RS10070	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
NP805_RS10075	COG1053	succinate dehydrogenase
NP805_RS10085	COG0567	Dehydrogenase, E1 component
NP805_RS10090	COG0508	dehydrogenase complex catalyzes the overall conversion of
NP805_RS10095	COG0045	succinate-CoA ligase (ADP-forming) activity
NP805_RS10100	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NP805_RS10105	COG2983	Belongs to the UPF0260 family
NP805_RS10110	COG1882	Formate acetyltransferase
NP805_RS10115	COG2116	formate transmembrane transporter activity
NP805_RS10120	COG1944	ATP diphosphatase activity
NP805_RS10125	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NP805_RS10130	COG0612	Peptidase, M16
NP805_RS10145	COG0589	response to stress
NP805_RS10150	COG3039	Transposase
NP805_RS10155	COG0589	response to stress
NP805_RS10165	COG2910	NAD(P)H-binding
NP805_RS10170	COG0583	DNA-binding transcription factor activity
NP805_RS10180	COG2207	Transcriptional regulator
NP805_RS10180	COG3708	Transcriptional regulator
NP805_RS10185	COG4774	siderophore transport
NP805_RS10195	COG0583	DNA-binding transcription factor activity
NP805_RS10200	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
NP805_RS10210	COG0517	IMP dehydrogenase activity
NP805_RS10225	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
NP805_RS10240	COG3033	Beta-eliminating lyase
NP805_RS10255	COG4235	cytochrome complex assembly
NP805_RS10255	COG3088	subunit of a heme lyase
NP805_RS10270	COG3301	Polysulphide reductase, NrfD
NP805_RS10275	COG0437	4 iron, 4 sulfur cluster binding
NP805_RS10280	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
NP805_RS10290	COG0247	lactate metabolic process
NP805_RS10295	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
NP805_RS10300	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NP805_RS10305	COG3012	SEC-C Motif Domain Protein
NP805_RS10310	COG0840	transmembrane signaling receptor activity
NP805_RS10315	COG1940	carbohydrate kinase activity
NP805_RS10315	COG1846	Transcriptional regulator
NP805_RS10320	COG3290	protein histidine kinase activity
NP805_RS10325	COG4565	transcriptional regulatory protein
NP805_RS10345	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
NP805_RS10350	COG2985	domain, Protein
NP805_RS10350	COG0569	domain protein
NP805_RS10360	COG0556	nucleotide-excision repair
NP805_RS10370	COG0586	Pfam SNARE associated Golgi protein
NP805_RS10375	COG3385	transposase activity
NP805_RS10380	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
NP805_RS10390	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NP805_RS10395	COG2186	Transcriptional regulator
NP805_RS10400	COG2719	SpoVR family
NP805_RS10410	COG2766	serine protein kinase
NP805_RS10415	COG0514	ATP-dependent DNA helicase (RecQ)
NP805_RS10420	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
NP805_RS10425	COG0814	amino acid
NP805_RS10445	COG3385	transposase activity
NP805_RS10465	COG0058	SHG alpha-glucan phosphorylase activity
NP805_RS10470	COG0471	metal ion transport
NP805_RS10475	COG3118	belongs to the thioredoxin family
NP805_RS10485	COG1132	(ABC) transporter
NP805_RS10490	COG1132	(ABC) transporter
NP805_RS10500	COG2501	S4 domain
NP805_RS10510	COG3243	poly(R)-hydroxyalkanoic acid synthase
NP805_RS10530	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NP805_RS10535	COG2329	Antibiotic biosynthesis monooxygenase
NP805_RS10575	COG1742	UPF0060 membrane protein
NP805_RS10585	COG0456	acetyltransferase
NP805_RS10590	COG0513	Belongs to the DEAD box helicase family
NP805_RS10595	COG0386	Belongs to the glutathione peroxidase family
NP805_RS10605	COG1181	Belongs to the D-alanine--D-alanine ligase family
NP805_RS10615	COG3148	PFAM DTW domain containing protein
NP805_RS10620	COG0730	response to heat
NP805_RS10625	COG0583	DNA-binding transcription factor activity
NP805_RS10640	COG3593	DNA synthesis involved in DNA repair
NP805_RS10700	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NP805_RS10705	COG1011	Hydrolase
NP805_RS10710	COG1473	amidohydrolase
NP805_RS10720	COG0205	6-phosphofructokinase activity
NP805_RS10730	COG1434	Gram-negative-bacterium-type cell wall biogenesis
NP805_RS10735	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NP805_RS10745	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
NP805_RS10750	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
NP805_RS10775	COG0242	peptide deformylase activity
NP805_RS10780	COG3039	Transposase
NP805_RS10815	COG4681	YaeQ
NP805_RS10835	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP805_RS10850	COG3134	Outer membrane lipoprotein
NP805_RS10860	COG1288	antiporter activity
NP805_RS10870	COG0318	PFAM AMP-dependent synthetase and ligase
NP805_RS10880	COG3039	Transposase
NP805_RS10890	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NP805_RS10890	COG0140	phosphoribosyl-ATP diphosphatase activity
NP805_RS10895	COG0107	imidazoleglycerol-phosphate synthase activity
NP805_RS10900	COG0784	Response regulator, receiver
NP805_RS10900	COG2198	Histidine kinase
NP805_RS10900	COG2205	protein histidine kinase activity
NP805_RS10905	COG2199	diguanylate cyclase activity
NP805_RS10910	COG3437	response regulator, receiver
NP805_RS10915	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
NP805_RS10920	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
NP805_RS10925	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
NP805_RS10925	COG0131	Imidazoleglycerol-phosphate dehydratase
NP805_RS10930	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NP805_RS10940	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NP805_RS10945	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NP805_RS10955	COG1199	ATP-dependent helicase activity
NP805_RS10960	COG1214	PFAM Peptidase M22, glycoprotease
NP805_RS10970	COG2267	carboxylic ester hydrolase activity
NP805_RS10975	COG0318	PFAM AMP-dependent synthetase and ligase
NP805_RS10995	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
NP805_RS11000	COG2832	Protein of unknown function (DUF454)
NP805_RS11005	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NP805_RS11010	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NP805_RS11015	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NP805_RS11020	COG3314	Sporulation integral membrane protein YlbJ
NP805_RS11025	COG2197	response regulator
NP805_RS11030	COG0617	tRNA 3'-terminal CCA addition
NP805_RS11030	COG0517	IMP dehydrogenase activity
NP805_RS11030	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NP805_RS11035	COG1643	Atp-dependent helicase
NP805_RS11045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NP805_RS11050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NP805_RS11055	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
NP805_RS11060	COG0709	Synthesizes selenophosphate from selenide and ATP
NP805_RS11075	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NP805_RS11080	COG0840	transmembrane signaling receptor activity
NP805_RS11085	COG1254	Belongs to the acylphosphatase family
NP805_RS11090	COG0625	glutathione transferase activity
NP805_RS11095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NP805_RS11095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NP805_RS11100	COG0489	protein tyrosine kinase activity
NP805_RS11105	COG0572	uridine kinase
NP805_RS11110	COG0717	Belongs to the dCTP deaminase family
NP805_RS11115	COG0306	phosphate transporter
NP805_RS11120	COG1530	ribonuclease E activity
NP805_RS11130	COG0546	phosphoglycolate phosphatase activity
NP805_RS11135	COG0424	maF-like protein
NP805_RS11140	COG1399	metal-binding, possibly nucleic acid-binding protein
NP805_RS11145	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NP805_RS11150	COG0416	fatty acid biosynthetic process
NP805_RS11155	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NP805_RS11165	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS11170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NP805_RS11175	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NP805_RS11180	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NP805_RS11185	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NP805_RS11190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NP805_RS11195	COG0470	DNA polymerase III
NP805_RS11200	COG0084	hydrolase, TatD family'
NP805_RS11215	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
NP805_RS11215	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NP805_RS11220	COG3008	intermembrane lipid transfer
NP805_RS11225	COG2995	paraquat-inducible protein a
NP805_RS11235	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
NP805_RS11240	COG0372	Belongs to the citrate synthase family
NP805_RS11260	COG5433	transposase activity
NP805_RS11290	COG1067	ATP-dependent peptidase activity
NP805_RS11295	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NP805_RS11310	COG0488	(ABC) transporter
NP805_RS11320	COG0116	Belongs to the methyltransferase superfamily
NP805_RS11320	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NP805_RS11330	COG0167	dihydroorotate dehydrogenase activity
NP805_RS11335	COG2902	Dehydrogenase
NP805_RS11345	COG0308	aminopeptidase N
NP805_RS11355	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
NP805_RS11360	COG1956	GAF domain-containing protein
NP805_RS11370	COG3278	Belongs to the heme-copper respiratory oxidase family
NP805_RS11385	COG2010	Cytochrome c
NP805_RS11395	COG2217	Heavy metal translocating P-type atpase
NP805_RS11410	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NP805_RS11415	COG0589	response to stress
NP805_RS11420	COG0037	tRNA processing
NP805_RS11435	COG0625	glutathione transferase activity
NP805_RS11440	COG1869	D-ribose catabolic process
NP805_RS11445	COG1129	ABC transporter
NP805_RS11450	COG1172	Belongs to the binding-protein-dependent transport system permease family
NP805_RS11455	COG1879	ABC-type sugar transport system periplasmic component
NP805_RS11460	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NP805_RS11465	COG1609	Transcriptional regulator
NP805_RS11470	COG2199	diguanylate cyclase activity
NP805_RS11500	COG0776	regulation of translation
NP805_RS11505	COG0072	phenylalanine-tRNA ligase activity
NP805_RS11505	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NP805_RS11510	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NP805_RS11515	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NP805_RS11520	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NP805_RS11525	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NP805_RS11530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NP805_RS11545	COG3385	transposase activity
NP805_RS11555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
NP805_RS11565	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NP805_RS11570	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NP805_RS11575	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NP805_RS11580	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
NP805_RS11585	COG3313	Fe-S protein
NP805_RS11590	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
NP805_RS11590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP805_RS11590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP805_RS11595	COG1105	Belongs to the carbohydrate kinase PfkB family
NP805_RS11600	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS11600	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS11605	COG1609	Transcriptional regulator
NP805_RS11610	COG0814	amino acid
NP805_RS11620	COG5654	RES domain protein
NP805_RS11625	COG0513	Belongs to the DEAD box helicase family
NP805_RS11635	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NP805_RS11640	COG2890	protein-(glutamine-N5) methyltransferase activity
NP805_RS11645	COG2840	Smr protein MutS2
NP805_RS11650	COG3706	GGDEF domain
NP805_RS11680	COG2824	Alkylphosphonate utilization operon protein PhnA
NP805_RS11685	COG1024	Enoyl-CoA hydratase
NP805_RS11685	COG1250	3-hydroxyacyl-CoA dehydrogenase
NP805_RS11690	COG0183	Belongs to the thiolase family
NP805_RS11695	COG0714	Associated with various cellular activities
NP805_RS11735	COG2067	long-chain fatty acid transport protein
NP805_RS11740	COG2067	long-chain fatty acid transport protein
NP805_RS11745	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NP805_RS11760	COG1301	dicarboxylic acid transport
NP805_RS11765	COG3123	guanosine phosphorylase activity
NP805_RS11770	COG1760	l-serine dehydratase
NP805_RS11775	COG1760	l-serine dehydratase
NP805_RS11780	COG2951	lytic endotransglycosylase activity
NP805_RS11785	COG3100	YcgL domain-containing protein
NP805_RS11790	COG0850	regulation of cytokinetic process
NP805_RS11795	COG2894	cell division
NP805_RS11800	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
NP805_RS11805	COG3099	Belongs to the UPF0263 family
NP805_RS11810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NP805_RS11855	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
NP805_RS11860	COG0697	spore germination
NP805_RS11865	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
NP805_RS11870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NP805_RS11880	COG0307	riboflavin synthase, alpha
NP805_RS11945	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NP805_RS11960	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NP805_RS12050	COG4372	Transposase
NP805_RS12165	COG0417	DNA replication proofreading
NP805_RS12175	COG2199	diguanylate cyclase activity
NP805_RS12175	COG2203	Gaf domain
NP805_RS12190	COG1560	Kdo2-lipid A biosynthetic process
NP805_RS12195	COG1560	Kdo2-lipid A biosynthetic process
NP805_RS12205	COG0583	DNA-binding transcription factor activity
NP805_RS12210	COG0673	inositol 2-dehydrogenase activity
NP805_RS12215	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NP805_RS12220	COG0583	DNA-binding transcription factor activity
NP805_RS12230	COG2723	6-phospho-beta-galactosidase activity
NP805_RS12235	COG0583	DNA-binding transcription factor activity
NP805_RS12240	COG1879	ABC-type sugar transport system periplasmic component
NP805_RS12245	COG1129	ABC transporter
NP805_RS12250	COG1172	Belongs to the binding-protein-dependent transport system permease family
NP805_RS12255	COG1172	Belongs to the binding-protein-dependent transport system permease family
NP805_RS12260	COG4251	negative regulation of phosphorylation
NP805_RS12260	COG2203	Gaf domain
NP805_RS12260	COG5001	Diguanylate cyclase
NP805_RS12260	COG3706	GGDEF domain
NP805_RS12265	COG2823	Periplasmic or secreted lipoprotein
NP805_RS12340	COG0583	DNA-binding transcription factor activity
NP805_RS12345	COG0778	Nitroreductase
NP805_RS12400	COG3267	Type II secretory pathway component ExeA
NP805_RS12400	COG3409	Peptidoglycan-binding domain 1 protein
NP805_RS12420	COG0730	response to heat
NP805_RS12430	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS12440	COG1024	Enoyl-CoA hydratase
NP805_RS12445	COG1024	Enoyl-CoA hydratase
NP805_RS12450	COG1960	acyl-CoA dehydrogenase activity
NP805_RS12460	COG1960	acyl-CoA dehydrogenase activity
NP805_RS12465	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NP805_RS12470	COG1024	Enoyl-CoA hydratase
NP805_RS12500	COG1584	GPR1 FUN34 yaaH family protein
NP805_RS12510	COG0456	acetyltransferase
NP805_RS12515	COG1115	amino acid carrier protein
NP805_RS12520	COG1024	Enoyl-CoA hydratase
NP805_RS12520	COG1250	3-hydroxyacyl-CoA dehydrogenase
NP805_RS12530	COG0517	IMP dehydrogenase activity
NP805_RS12535	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NP805_RS12545	COG0488	(ABC) transporter
NP805_RS12550	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
NP805_RS12555	COG0776	regulation of translation
NP805_RS12560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NP805_RS12565	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NP805_RS12570	COG0740	serine-type endopeptidase activity
NP805_RS12575	COG0544	peptidyl-prolyl cis-trans isomerase activity
NP805_RS12585	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NP805_RS12590	COG4591	ABC-type transport system involved in lipoprotein release permease component
NP805_RS12595	COG1136	(ABC) transporter
NP805_RS12600	COG4591	ABC-type transport system involved in lipoprotein release permease component
NP805_RS12610	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NP805_RS12615	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
NP805_RS12620	COG4166	transmembrane transport
NP805_RS12625	COG0697	spore germination
NP805_RS12635	COG2062	phosphohistidine phosphatase, SixA
NP805_RS12640	COG1025	Belongs to the peptidase M16 family
NP805_RS12685	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NP805_RS12685	COG0519	Catalyzes the synthesis of GMP from XMP
NP805_RS12690	COG0516	GMP reductase activity
NP805_RS12690	COG0517	IMP dehydrogenase activity
NP805_RS12695	COG5433	transposase activity
NP805_RS12705	COG1570	exodeoxyribonuclease VII activity
NP805_RS12720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NP805_RS12725	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NP805_RS12730	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NP805_RS12770	COG4771	TonB-dependent receptor
NP805_RS12775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP805_RS12780	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP805_RS12785	COG1120	ATPase activity
NP805_RS12795	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NP805_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS12815	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NP805_RS12820	COG3433	isochorismatase activity
NP805_RS12820	COG1535	isochorismatase
NP805_RS12825	COG1021	2,3-dihydroxybenzoate-AMP ligase
NP805_RS12845	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NP805_RS12850	COG5001	Diguanylate cyclase
NP805_RS12850	COG3300	MHYT domain
NP805_RS12865	COG0840	transmembrane signaling receptor activity
NP805_RS12870	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NP805_RS12875	COG3788	relative of glutathione S-transferase, MAPEG superfamily
NP805_RS12880	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NP805_RS12885	COG0563	adenylate kinase activity
NP805_RS12890	COG0326	Molecular chaperone. Has ATPase activity
NP805_RS12895	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NP805_RS12920	COG3383	formate dehydrogenase (NAD+) activity
NP805_RS12925	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
NP805_RS12930	COG5433	transposase activity
NP805_RS12935	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NP805_RS12945	COG5433	transposase activity
NP805_RS12970	COG3039	Transposase
NP805_RS12980	COG3039	Transposase
NP805_RS12985	COG3039	Transposase
NP805_RS12990	COG5642	Protein of unknown function (DUF2384)
NP805_RS13000	COG3039	Transposase
NP805_RS13015	COG4372	Transposase
NP805_RS13065	COG1435	thymidine kinase activity
NP805_RS13070	COG1757	Na H antiporter
NP805_RS13075	COG2916	Histone family protein nucleoid-structuring protein H-NS
NP805_RS13080	COG2096	Adenosyltransferase
NP805_RS13085	COG3530	Putative quorum-sensing-regulated virulence factor
NP805_RS13090	COG0602	queuosine metabolic process
NP805_RS13095	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
NP805_RS13110	COG0284	orotidine-5'-phosphate decarboxylase activity
NP805_RS13115	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
NP805_RS13125	COG0776	regulation of translation
NP805_RS13130	COG0539	negative regulation of cytoplasmic translation
NP805_RS13135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NP805_RS13140	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NP805_RS13150	COG0583	DNA-binding transcription factor activity
NP805_RS13155	COG2814	Major facilitator Superfamily
NP805_RS13175	COG5001	Diguanylate cyclase
NP805_RS13175	COG3300	MHYT domain
NP805_RS13185	COG0583	DNA-binding transcription factor activity
NP805_RS13190	COG3437	response regulator, receiver
NP805_RS13205	COG0589	response to stress
NP805_RS13225	COG4989	oxidoreductase activity
NP805_RS13230	COG0724	RNA recognition motif
NP805_RS13240	COG1126	abc transporter atp-binding protein
NP805_RS13245	COG0765	amino acid transport
NP805_RS13250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NP805_RS13255	COG4597	amino acid ABC transporter
NP805_RS13270	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
NP805_RS13285	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NP805_RS13290	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NP805_RS13295	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NP805_RS13295	COG0649	NAD binding
NP805_RS13310	COG1034	ATP synthesis coupled electron transport
NP805_RS13315	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NP805_RS13320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NP805_RS13325	COG0839	Belongs to the complex I subunit 6 family
NP805_RS13330	COG0713	ATP synthesis coupled electron transport
NP805_RS13340	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NP805_RS13345	COG1007	ATP synthesis coupled electron transport
NP805_RS13365	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NP805_RS13370	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NP805_RS13405	COG0537	adenosine 5'-monophosphoramidase activity
NP805_RS13420	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NP805_RS13435	COG1301	dicarboxylic acid transport
NP805_RS13445	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NP805_RS13450	COG0861	Integral membrane protein TerC family
NP805_RS13460	COG0444	Belongs to the ABC transporter superfamily
NP805_RS13465	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NP805_RS13470	COG0601	transmembrane transport
NP805_RS13480	COG2095	MarC family integral membrane protein
NP805_RS13490	COG1012	belongs to the aldehyde dehydrogenase family
NP805_RS13490	COG1454	alcohol dehydrogenase
NP805_RS13495	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
NP805_RS13495	COG2199	diguanylate cyclase activity
NP805_RS13500	COG3275	phosphorelay sensor kinase activity
NP805_RS13505	COG3279	Response regulator of the LytR AlgR family
NP805_RS13510	COG1966	Carbon starvation protein
NP805_RS13520	COG1566	PFAM secretion protein HlyD family protein
NP805_RS13525	COG1061	Type III restriction enzyme res subunit
NP805_RS13530	COG2027	D-alanyl-D-alanine carboxypeptidase
NP805_RS13535	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
NP805_RS13545	COG0436	Aminotransferase
NP805_RS13550	COG1288	antiporter activity
NP805_RS13555	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
NP805_RS13655	COG4397	Mu-like prophage major head subunit gpT
NP805_RS13660	COG4388	Caudovirus prohead serine protease
NP805_RS13680	COG4383	Mu-like prophage protein gp29
NP805_RS13685	COG4373	Mu-like prophage FluMu protein gp28
NP805_RS13695	COG0640	Transcriptional regulator
NP805_RS13800	COG2932	Transcriptional regulator
NP805_RS13820	COG0697	spore germination
NP805_RS13825	COG4657	Part of a membrane complex involved in electron transport
NP805_RS13830	COG2878	Part of a membrane complex involved in electron transport
NP805_RS13840	COG4658	electron transport chain
NP805_RS13845	COG4659	FMN binding
NP805_RS13850	COG4660	Part of a membrane complex involved in electron transport
NP805_RS13855	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NP805_RS13860	COG0346	lactoylglutathione lyase activity
NP805_RS13875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
NP805_RS13880	COG2056	Na+-H+ antiporter family
NP805_RS13885	COG3639	organic phosphonate transmembrane transporter activity
NP805_RS13890	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
NP805_RS13895	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NP805_RS13900	COG0513	Belongs to the DEAD box helicase family
NP805_RS13905	COG2050	protein possibly involved in aromatic compounds catabolism
NP805_RS13915	COG0247	lactate metabolic process
NP805_RS13915	COG0277	FAD linked oxidase domain protein
NP805_RS13925	COG1253	flavin adenine dinucleotide binding
NP805_RS13930	COG1902	pentaerythritol trinitrate reductase activity
NP805_RS13940	COG0647	UMP catabolic process
NP805_RS13960	COG0367	asparagine synthase
NP805_RS13970	COG0625	glutathione transferase activity
NP805_RS13980	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
NP805_RS13995	COG0564	pseudouridine synthase activity
NP805_RS14000	COG5001	Diguanylate cyclase
NP805_RS14005	COG0840	transmembrane signaling receptor activity
NP805_RS14010	COG0582	viral genome integration into host DNA
NP805_RS14035	COG2916	Histone family protein nucleoid-structuring protein H-NS
NP805_RS14045	COG4983	Phage plasmid primase, P4 family domain protein
NP805_RS14095	COG2003	Belongs to the UPF0758 family
NP805_RS14180	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NP805_RS14190	COG0670	Belongs to the BI1 family
NP805_RS14195	COG1289	transmembrane transporter activity
NP805_RS14200	COG2920	part of a sulfur-relay system
NP805_RS14205	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
NP805_RS14210	COG0285	dihydrofolate synthase activity
NP805_RS14215	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
NP805_RS14220	COG0101	tRNA pseudouridine synthase activity
NP805_RS14230	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
NP805_RS14235	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NP805_RS14240	COG0671	phosphoesterase, PA-phosphatase related
NP805_RS14290	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NP805_RS14290	COG0574	Belongs to the PEP-utilizing enzyme family
NP805_RS14295	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
NP805_RS14350	COG1242	4 iron, 4 sulfur cluster binding
NP805_RS14355	COG0070	glutamate synthase
NP805_RS14355	COG0067	glutamate synthase
NP805_RS14355	COG0069	glutamate synthase activity
NP805_RS14360	COG0493	'glutamate synthase
NP805_RS14375	COG0789	Transcriptional regulator
NP805_RS14390	COG4104	PAAR repeat-containing protein
NP805_RS14400	COG0513	Belongs to the DEAD box helicase family
NP805_RS14405	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NP805_RS14430	COG3039	Transposase
NP805_RS14445	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NP805_RS14450	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
NP805_RS14455	COG0505	Belongs to the CarA family
NP805_RS14460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NP805_RS14480	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NP805_RS14485	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
NP805_RS14490	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NP805_RS14495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NP805_RS14500	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NP805_RS14505	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
NP805_RS14515	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NP805_RS14515	COG2205	protein histidine kinase activity
NP805_RS14560	COG2119	membrane
NP805_RS14590	COG2199	diguanylate cyclase activity
NP805_RS14590	COG2203	Gaf domain
NP805_RS14625	COG0419	ATPase involved in DNA repair
NP805_RS14645	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NP805_RS14655	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
NP805_RS14660	COG2261	transglycosylase associated protein
NP805_RS14695	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
NP805_RS14710	COG3039	Transposase
NP805_RS14715	COG3039	Transposase
NP805_RS14800	COG0582	viral genome integration into host DNA
NP805_RS14825	COG0322	excinuclease ABC activity
NP805_RS14830	COG2197	response regulator
NP805_RS14835	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
NP805_RS14840	COG2835	tetraacyldisaccharide 4'-kinase activity
NP805_RS14845	COG1663	tetraacyldisaccharide 4'-kinase activity
NP805_RS14850	COG1132	(ABC) transporter
NP805_RS14855	COG0658	competence protein
NP805_RS14855	COG2333	competence protein COMEC
NP805_RS14870	COG0433	COG0433 Predicted ATPase
NP805_RS14875	COG1448	Aminotransferase
NP805_RS14890	COG1199	ATP-dependent helicase activity
NP805_RS14905	COG0123	including yeast histone deacetylase and acetoin utilization protein
NP805_RS14915	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NP805_RS14920	COG1785	Belongs to the alkaline phosphatase family
NP805_RS14940	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP805_RS14955	COG2271	Major facilitator Superfamily
NP805_RS14960	COG3706	GGDEF domain
NP805_RS14965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NP805_RS14970	COG0765	amino acid transport
NP805_RS14975	COG1126	abc transporter atp-binding protein
NP805_RS14985	COG0531	amino acid
NP805_RS15000	COG1253	flavin adenine dinucleotide binding
NP805_RS15005	COG0704	Plays a role in the regulation of phosphate uptake
NP805_RS15010	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NP805_RS15015	COG0581	inorganic phosphate transmembrane transporter activity
NP805_RS15020	COG0573	inorganic phosphate transmembrane transporter activity
NP805_RS15025	COG0590	tRNA wobble adenosine to inosine editing
NP805_RS15045	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
NP805_RS15070	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NP805_RS15075	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NP805_RS15080	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NP805_RS15085	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NP805_RS15115	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NP805_RS15120	COG0248	Ppx GppA phosphatase
NP805_RS15125	COG2239	Acts as a magnesium transporter
NP805_RS15150	COG1705	Flagellar rod assembly protein muramidase FlgJ
NP805_RS15150	COG3951	Flagellar rod assembly protein muramidase FlgJ
NP805_RS15155	COG1706	bacterial-type flagellum-dependent cell motility
NP805_RS15160	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
NP805_RS15175	COG1749	Flagellar hook protein flgE
NP805_RS15190	COG1815	bacterial-type flagellum-dependent cell motility
NP805_RS15195	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
NP805_RS15200	COG0835	chemotaxis
NP805_RS15200	COG0784	Response regulator, receiver
NP805_RS15220	COG0622	Phosphoesterase
NP805_RS15225	COG4166	transmembrane transport
NP805_RS15250	COG0697	spore germination
NP805_RS15255	COG4166	transmembrane transport
NP805_RS15280	COG1278	Cold shock
NP805_RS15325	COG3132	Protein of unknown function, DUF480
NP805_RS15335	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NP805_RS15345	COG0438	transferase activity, transferring glycosyl groups
NP805_RS15350	COG1215	transferase activity, transferring glycosyl groups
NP805_RS15365	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP805_RS15380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NP805_RS15380	COG2755	lipolytic protein G-D-S-L family
NP805_RS15410	COG1450	Type ii and iii secretion system protein
NP805_RS15445	COG2165	general secretion pathway protein
NP805_RS15455	COG1459	type II secretion system
NP805_RS15480	COG1091	dTDP-4-dehydrorhamnose reductase activity
NP805_RS15495	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NP805_RS15500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NP805_RS15505	COG1309	transcriptional regulator
NP805_RS15520	COG3385	transposase activity
NP805_RS15525	COG1946	Acyl-CoA thioesterase
NP805_RS15535	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NP805_RS15545	COG0009	L-threonylcarbamoyladenylate synthase
NP805_RS15560	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
NP805_RS15565	COG0512	Glutamine amidotransferase of anthranilate synthase
NP805_RS15565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NP805_RS15570	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NP805_RS15575	COG0134	indole-3-glycerol-phosphate synthase activity
NP805_RS15575	COG0135	phosphoribosylanthranilate isomerase activity
NP805_RS15580	COG0133	tryptophan synthase activity
NP805_RS15585	COG0159	tryptophan synthase activity
NP805_RS15590	COG3039	Transposase
NP805_RS15600	COG0783	Belongs to the Dps family
NP805_RS15625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP805_RS15625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS15625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP805_RS15635	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NP805_RS15645	COG1187	pseudouridine synthase activity
NP805_RS15655	COG0482	sulfurtransferase activity
NP805_RS15660	COG2915	High frequency lysogenization protein hflD homolog
NP805_RS15665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NP805_RS15670	COG2850	peptidyl-arginine hydroxylation
NP805_RS15675	COG3153	acetyltransferase
NP805_RS15690	COG0259	pyridoxamine-phosphate oxidase activity
NP805_RS15705	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NP805_RS15705	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NP805_RS15710	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
NP805_RS15725	COG4235	cytochrome complex assembly
NP805_RS15725	COG3088	subunit of a heme lyase
NP805_RS15735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NP805_RS15740	COG1138	Cytochrome C-type biogenesis protein
NP805_RS15745	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
NP805_RS15750	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NP805_RS15755	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NP805_RS15760	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
NP805_RS15780	COG0835	chemotaxis
NP805_RS15790	COG1192	Involved in chromosome partitioning
NP805_RS15795	COG1360	Flagellar Motor Protein
NP805_RS15800	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NP805_RS15805	COG2201	protein-glutamate methylesterase activity
NP805_RS15810	COG0643	Histidine kinase
NP805_RS15810	COG0784	Response regulator, receiver
NP805_RS15810	COG2198	Histidine kinase
NP805_RS15815	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
NP805_RS15840	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NP805_RS15850	COG1684	flagellar biosynthetic protein fliR
NP805_RS15905	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NP805_RS15915	COG1677	Flagellar hook-basal body complex protein FliE
NP805_RS15925	COG1574	metal-dependent hydrolase with the TIM-barrel fold
NP805_RS15945	COG1342	Belongs to the UPF0251 family
NP805_RS16035	COG1737	Transcriptional regulator
NP805_RS16040	COG0469	pyruvate kinase activity
NP805_RS16050	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NP805_RS16055	COG5433	transposase activity
NP805_RS16060	COG1960	acyl-CoA dehydrogenase activity
NP805_RS16070	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NP805_RS16115	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NP805_RS16140	COG5433	transposase activity
NP805_RS16180	COG2314	TM2 domain
NP805_RS16190	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NP805_RS16200	COG1136	(ABC) transporter
NP805_RS16275	COG2003	Belongs to the UPF0758 family
NP805_RS16315	COG3328	transposase activity
NP805_RS16325	COG2801	Transposase and inactivated derivatives
NP805_RS16345	COG1376	ErfK ybiS ycfS ynhG family protein
NP805_RS16345	COG1388	LysM domain
NP805_RS16360	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
NP805_RS16365	COG0791	NLP P60 protein
NP805_RS16370	COG2091	lysine biosynthetic process via aminoadipic acid
NP805_RS16375	COG3118	belongs to the thioredoxin family
NP805_RS16385	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
NP805_RS16390	COG0788	formyltetrahydrofolate deformylase activity
NP805_RS16400	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NP805_RS16420	COG0366	Alpha amylase catalytic
NP805_RS16425	COG0739	heme binding
NP805_RS16425	COG0741	lytic transglycosylase activity
NP805_RS16425	COG1196	nuclear chromosome segregation
NP805_RS16430	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NP805_RS16435	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NP805_RS16440	COG0673	inositol 2-dehydrogenase activity
NP805_RS16445	COG0583	DNA-binding transcription factor activity
NP805_RS16515	COG3385	transposase activity
NP805_RS16520	COG1032	radical SAM domain protein
NP805_RS16530	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NP805_RS16535	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NP805_RS16540	COG3706	GGDEF domain
NP805_RS16545	COG1752	Esterase of the alpha-beta hydrolase superfamily
NP805_RS16580	COG0281	malic enzyme
NP805_RS16585	COG2207	Transcriptional regulator
NP805_RS16590	COG0534	Mate efflux family protein
NP805_RS16610	COG0095	Lipoate-protein ligase
NP805_RS16615	COG1115	amino acid carrier protein
NP805_RS16620	COG0019	diaminopimelate decarboxylase activity
NP805_RS16660	COG1131	(ABC) transporter
NP805_RS16665	COG0545	Peptidyl-prolyl cis-trans isomerase
NP805_RS16680	COG3142	Participates in the control of copper homeostasis
NP805_RS16685	COG1940	carbohydrate kinase activity
NP805_RS16705	COG5002	protein histidine kinase activity
NP805_RS16710	COG0745	RESPONSE REGULATOR receiver
NP805_RS16715	COG0346	lactoylglutathione lyase activity
NP805_RS16720	COG3706	GGDEF domain
NP805_RS16725	COG3284	Transcriptional regulator
NP805_RS16740	COG0697	spore germination
NP805_RS16755	COG4372	Transposase
NP805_RS16765	COG0667	Aldo Keto reductase
NP805_RS16780	COG3290	protein histidine kinase activity
NP805_RS16785	COG0281	malic enzyme
NP805_RS16800	COG1846	Transcriptional regulator
NP805_RS16805	COG1566	PFAM secretion protein HlyD family protein
NP805_RS16830	COG0602	queuosine metabolic process
NP805_RS16835	COG1328	CTP reductase activity
NP805_RS16845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NP805_RS16850	COG3115	cell septum assembly
NP805_RS16855	COG1196	nuclear chromosome segregation
NP805_RS16865	COG2860	membrane
NP805_RS16875	COG3108	Peptidase M15
NP805_RS16880	COG2989	Protein conserved in bacteria
NP805_RS16895	COG0463	Glycosyl transferase, family 2
NP805_RS16910	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NP805_RS16915	COG0739	heme binding
NP805_RS16920	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
NP805_RS16925	COG3039	Transposase
NP805_RS16945	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NP805_RS16955	COG3091	SprT-like family
NP805_RS16965	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NP805_RS16970	COG0189	ligase activity
NP805_RS16980	COG1678	Uncharacterized ACR, COG1678
NP805_RS16985	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NP805_RS16995	COG0714	Associated with various cellular activities
NP805_RS17010	COG1115	amino acid carrier protein
NP805_RS17015	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NP805_RS17030	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NP805_RS17050	COG2912	Transglutaminase-like superfamily
NP805_RS17060	COG2890	protein-(glutamine-N5) methyltransferase activity
NP805_RS17065	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NP805_RS17070	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NP805_RS17075	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
NP805_RS17080	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NP805_RS17090	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
NP805_RS17095	COG0737	Belongs to the 5'-nucleotidase family
NP805_RS17100	COG0193	aminoacyl-tRNA hydrolase activity
NP805_RS17105	COG0012	GTP binding
NP805_RS17150	COG0471	metal ion transport
NP805_RS17150	COG0490	domain, Protein
NP805_RS17160	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NP805_RS17180	COG0366	Alpha amylase catalytic
NP805_RS17190	COG0488	(ABC) transporter
NP805_RS17200	COG0674	pyruvate-flavodoxin oxidoreductase activity
NP805_RS17200	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NP805_RS17200	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NP805_RS17200	COG1013	pyruvate-flavodoxin oxidoreductase activity
NP805_RS17210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NP805_RS17220	COG1012	belongs to the aldehyde dehydrogenase family
NP805_RS17230	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NP805_RS17245	COG0180	Tryptophanyl-tRNA synthetase
NP805_RS17250	COG0546	phosphoglycolate phosphatase activity
NP805_RS17255	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NP805_RS17260	COG0338	D12 class N6 adenine-specific DNA methyltransferase
NP805_RS17270	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NP805_RS17275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NP805_RS17305	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NP805_RS17310	COG0583	DNA-binding transcription factor activity
NP805_RS17315	COG0840	transmembrane signaling receptor activity
NP805_RS17330	COG0583	DNA-binding transcription factor activity
NP805_RS17345	COG0739	heme binding
NP805_RS17355	COG1511	domain protein
NP805_RS17355	COG3264	Mechanosensitive ion channel
NP805_RS17360	COG0584	glycerophosphoryl diester phosphodiesterase
NP805_RS17370	COG1053	succinate dehydrogenase
NP805_RS17375	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NP805_RS17380	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NP805_RS17385	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
NP805_RS17395	COG3214	Protein conserved in bacteria
NP805_RS17410	COG1022	Amp-dependent synthetase and ligase
NP805_RS17435	COG0642	Histidine kinase
NP805_RS17445	COG0516	GMP reductase activity
NP805_RS17455	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NP805_RS17465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NP805_RS17475	COG3706	GGDEF domain
NP805_RS17485	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NP805_RS17500	COG3706	GGDEF domain
NP805_RS17510	COG1335	isochorismatase
NP805_RS17515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
NP805_RS17520	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NP805_RS17525	COG1702	phosphate starvation-inducible protein PhoH
NP805_RS17530	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NP805_RS17535	COG4535	Mg2 and Co2 transporter CorC
NP805_RS17540	COG0815	Transfers the fatty acyl group on membrane lipoproteins
NP805_RS17545	COG2888	peptidyl-tyrosine sulfation
NP805_RS17550	COG0495	leucyl-tRNA aminoacylation
NP805_RS17570	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NP805_RS17575	COG0799	negative regulation of ribosome biogenesis
NP805_RS17580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NP805_RS17585	COG0768	penicillin binding
NP805_RS17590	COG0772	Belongs to the SEDS family
NP805_RS17595	COG2951	lytic endotransglycosylase activity
NP805_RS17600	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
NP805_RS17605	COG1686	Belongs to the peptidase S11 family
NP805_RS17610	COG2921	Belongs to the UPF0250 family
NP805_RS17615	COG0321	lipoyl(octanoyl) transferase activity
NP805_RS17620	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NP805_RS17630	COG3545	Serine hydrolase
NP805_RS17645	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
NP805_RS17655	COG1970	mechanosensitive ion channel activity
NP805_RS17660	COG4974	Belongs to the 'phage' integrase family
NP805_RS17675	COG0312	modulator of DNA gyrase
NP805_RS17720	COG3039	Transposase
NP805_RS17730	COG3039	Transposase
NP805_RS17765	COG0114	fumarate hydratase activity
NP805_RS17770	COG1422	Protein of unknown function (DUF1090)
NP805_RS17775	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
NP805_RS17780	COG3706	GGDEF domain
NP805_RS17785	COG2211	Major facilitator Superfamily
NP805_RS17790	COG1185	polyribonucleotide nucleotidyltransferase activity
NP805_RS17795	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NP805_RS17800	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NP805_RS17805	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NP805_RS17810	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NP805_RS17815	COG0195	Participates in both transcription termination and antitermination
NP805_RS17820	COG0779	Required for maturation of 30S ribosomal subunits
NP805_RS17835	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NP805_RS17840	COG0149	triose-phosphate isomerase activity
NP805_RS17845	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NP805_RS17850	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NP805_RS17860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
NP805_RS17865	COG1534	Rna-binding protein
NP805_RS17880	COG3861	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity
NP805_RS17890	COG1360	Flagellar Motor Protein
NP805_RS17895	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
NP805_RS17900	COG1722	exodeoxyribonuclease VII activity
NP805_RS17905	COG0142	geranyltranstransferase activity
NP805_RS17910	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NP805_RS17920	COG0601	transmembrane transport
NP805_RS17935	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
NP805_RS17940	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
NP805_RS17945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NP805_RS17950	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
NP805_RS17965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NP805_RS17965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
NP805_RS17970	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NP805_RS17985	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NP805_RS17995	COG3381	protein complex oligomerization
NP805_RS18025	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NP805_RS18030	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NP805_RS18035	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NP805_RS18040	COG0511	ligase activity, forming carbon-carbon bonds
NP805_RS18045	COG0439	Biotin carboxylase
NP805_RS18050	COG3924	membrane
NP805_RS18055	COG4145	pantothenate transmembrane transporter activity
NP805_RS18060	COG1263	PTS System
NP805_RS18060	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NP805_RS18060	COG2190	(PTS) system
NP805_RS18065	COG0583	DNA-binding transcription factor activity
NP805_RS18070	COG0604	alcohol dehydrogenase
NP805_RS18075	COG2264	protein methyltransferase activity
NP805_RS18080	COG0110	maltose O-acetyltransferase activity
NP805_RS18095	COG0778	Nitroreductase
NP805_RS18100	COG1902	pentaerythritol trinitrate reductase activity
NP805_RS18100	COG0446	pyridine nucleotide-disulphide oxidoreductase
NP805_RS18105	COG0616	signal peptide processing
NP805_RS18125	COG3139	Protein of unknown function (DUF1315)
NP805_RS18130	COG0252	asparaginase activity
NP805_RS18135	COG0786	glutamate:sodium symporter activity
NP805_RS18155	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NP805_RS18160	COG0384	phenazine biosynthesis protein PhzF
NP805_RS18165	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NP805_RS18170	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NP805_RS18175	COG0175	sulfate reduction
NP805_RS18180	COG2113	Glycine betaine
NP805_RS18185	COG4176	ABC-type proline glycine betaine transport system permease component
NP805_RS18205	COG3610	response to peptide
NP805_RS18215	COG2966	Psort location CytoplasmicMembrane, score
NP805_RS18225	COG0521	Mo-molybdopterin cofactor biosynthetic process
NP805_RS18235	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NP805_RS18240	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS18250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NP805_RS18275	COG2986	histidine ammonia-lyase
NP805_RS18290	COG0318	PFAM AMP-dependent synthetase and ligase
NP805_RS18300	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NP805_RS18305	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
NP805_RS18340	COG1858	cytochrome C peroxidase
NP805_RS18350	COG2313	pseudouridylate synthase activity
NP805_RS18355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NP805_RS18365	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NP805_RS18365	COG2146	nitrite reductase [NAD(P)H] activity
NP805_RS18370	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NP805_RS18370	COG2146	nitrite reductase [NAD(P)H] activity
NP805_RS18375	COG1116	anion transmembrane transporter activity
NP805_RS18380	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NP805_RS18385	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NP805_RS18385	COG1116	anion transmembrane transporter activity
NP805_RS18400	COG0243	molybdopterin cofactor binding
NP805_RS18425	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NP805_RS18430	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
NP805_RS18440	COG1073	alpha beta
NP805_RS18445	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NP805_RS18450	COG4974	Belongs to the 'phage' integrase family
NP805_RS18460	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NP805_RS18570	COG4695	Portal protein
NP805_RS18715	COG2195	Cleaves the N-terminal amino acid of tripeptides
NP805_RS18720	COG4608	Belongs to the ABC transporter superfamily
NP805_RS18725	COG0444	Belongs to the ABC transporter superfamily
NP805_RS18730	COG0747	negative chemotaxis
NP805_RS18735	COG4239	(ABC) transporter, permease
NP805_RS18740	COG4174	ABC transporter (Permease)
NP805_RS18745	COG4206	TonB-dependent receptor
NP805_RS18755	COG0811	peptide transport
NP805_RS18760	COG0811	peptide transport
NP805_RS18765	COG0848	biopolymer transport protein
NP805_RS18820	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NP805_RS18825	COG0840	transmembrane signaling receptor activity
NP805_RS18835	COG1278	Cold shock
NP805_RS18875	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NP805_RS18885	COG0688	phosphatidylethanolamine metabolic process
NP805_RS18890	COG4628	conserved protein (DUF2132)
NP805_RS18910	COG3300	MHYT domain
NP805_RS18910	COG5001	Diguanylate cyclase
NP805_RS18920	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
NP805_RS18945	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
NP805_RS18950	COG1012	belongs to the aldehyde dehydrogenase family
NP805_RS18955	COG1309	transcriptional regulator
NP805_RS18965	COG1132	(ABC) transporter
NP805_RS18975	COG2897	thiosulfate sulfurtransferase activity
NP805_RS18980	COG2066	Belongs to the glutaminase family
NP805_RS18985	COG3171	Protein conserved in bacteria
NP805_RS18990	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NP805_RS18995	COG2234	aminopeptidase activity
NP805_RS18995	COG4935	Belongs to the peptidase S8 family
NP805_RS19005	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NP805_RS19010	COG2200	EAL domain
NP805_RS19015	COG1090	epimerase
NP805_RS19020	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
NP805_RS19025	COG4181	ATPase activity
NP805_RS19030	COG2755	lipolytic protein G-D-S-L family
NP805_RS19035	COG0835	chemotaxis
NP805_RS19035	COG0784	Response regulator, receiver
NP805_RS19045	COG0569	domain protein
NP805_RS19045	COG2985	domain, Protein
NP805_RS19050	COG1272	protein, Hemolysin III
NP805_RS19055	COG0076	glutamate decarboxylase activity
NP805_RS19060	COG2917	probably involved in intracellular septation
NP805_RS19065	COG2350	Protein conserved in bacteria
NP805_RS19070	COG1218	3'(2'),5'-bisphosphate nucleotidase
NP805_RS19075	COG1555	photosystem II stabilization
NP805_RS19080	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NP805_RS19085	COG3104	oligopeptide transport
NP805_RS19090	COG0745	RESPONSE REGULATOR receiver
NP805_RS19105	COG0471	metal ion transport
NP805_RS19135	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
NP805_RS19150	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
NP805_RS19160	COG2189	Belongs to the N(4) N(6)-methyltransferase family
NP805_RS19175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NP805_RS19225	COG2003	Belongs to the UPF0758 family
NP805_RS19305	COG1280	lysine exporter protein (LysE YggA)
NP805_RS19330	COG0316	Belongs to the HesB IscA family
NP805_RS19340	COG0038	chloride channel
NP805_RS19345	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NP805_RS19360	COG0671	phosphoesterase, PA-phosphatase related
NP805_RS19370	COG0784	Response regulator, receiver
NP805_RS19370	COG3437	response regulator, receiver
NP805_RS19375	COG0583	DNA-binding transcription factor activity
NP805_RS19380	COG2076	Multidrug Resistance protein
NP805_RS19390	COG0346	lactoylglutathione lyase activity
NP805_RS19395	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NP805_RS19400	COG1643	Atp-dependent helicase
NP805_RS19410	COG1489	DNA binding
NP805_RS19415	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NP805_RS19420	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NP805_RS19425	COG0617	tRNA 3'-terminal CCA addition
NP805_RS19430	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
NP805_RS19435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
NP805_RS19440	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NP805_RS19450	COG0842	Transport permease protein
NP805_RS19455	COG1131	(ABC) transporter
NP805_RS19470	COG0163	prenyltransferase activity
NP805_RS19475	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NP805_RS19480	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NP805_RS19485	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
NP805_RS19495	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NP805_RS19495	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
NP805_RS19495	COG0506	proline dehydrogenase activity
NP805_RS19500	COG4991	sh3 domain protein
NP805_RS19505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NP805_RS19525	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NP805_RS19530	COG1640	4-alpha-glucanotransferase
NP805_RS19535	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NP805_RS19545	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NP805_RS19550	COG0840	transmembrane signaling receptor activity
NP805_RS19630	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
NP805_RS19635	COG2885	chlorophyll binding
NP805_RS19640	COG0823	Involved in the tonB-independent uptake of proteins
NP805_RS19655	COG0811	peptide transport
NP805_RS19660	COG0824	Thioesterase
NP805_RS19665	COG3790	cyd operon protein YbgE
NP805_RS19670	COG4890	Cyd operon protein YbgT
NP805_RS19675	COG1294	oxidase, subunit
NP805_RS19680	COG1271	oxidase subunit
NP805_RS19685	COG2255	four-way junction helicase activity
NP805_RS19690	COG0632	four-way junction helicase activity
NP805_RS19695	COG0840	transmembrane signaling receptor activity
NP805_RS19700	COG0442	prolyl-tRNA aminoacylation
NP805_RS19710	COG1902	pentaerythritol trinitrate reductase activity
NP805_RS19730	COG5001	Diguanylate cyclase
NP805_RS19730	COG3300	MHYT domain
NP805_RS19750	COG0714	Associated with various cellular activities
NP805_RS19760	COG0456	acetyltransferase
NP805_RS19770	COG1022	Amp-dependent synthetase and ligase
NP805_RS19780	COG2918	glutathione biosynthetic process
NP805_RS19785	COG0612	Peptidase, M16
NP805_RS19790	COG1238	metal cluster binding
NP805_RS19795	COG1064	alcohol dehydrogenase
NP805_RS19825	COG0359	binds to the 23S rRNA
NP805_RS19830	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NP805_RS19835	COG0360	Binds together with S18 to 16S ribosomal RNA
NP805_RS19840	COG1914	H( )-stimulated, divalent metal cation uptake system
NP805_RS19845	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NP805_RS19860	COG2153	protein acetylation
NP805_RS19870	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NP805_RS19875	COG0557	exoribonuclease II activity
NP805_RS19880	COG3706	GGDEF domain
NP805_RS19885	COG1854	S-ribosylhomocysteine lyase activity
NP805_RS19900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NP805_RS19900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
NP805_RS19970	COG4970	Tfp pilus assembly protein FimT
NP805_RS19975	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NP805_RS19980	COG1047	Peptidyl-prolyl cis-trans
NP805_RS19985	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NP805_RS19990	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NP805_RS19995	COG0196	riboflavin kinase activity
NP805_RS20000	COG0728	peptidoglycan biosynthetic process
NP805_RS20005	COG0268	Binds directly to 16S ribosomal RNA
NP805_RS20010	COG0640	Transcriptional regulator
NP805_RS20015	COG0583	DNA-binding transcription factor activity
NP805_RS20020	COG4974	Belongs to the 'phage' integrase family
NP805_RS20035	COG1396	sequence-specific DNA binding
NP805_RS20130	COG4695	Portal protein
NP805_RS20185	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
NP805_RS20270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NP805_RS20275	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NP805_RS20280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NP805_RS20290	COG1051	belongs to the nudix hydrolase family
NP805_RS20295	COG3066	DNA modification
NP805_RS20305	COG0335	large ribosomal subunit rRNA binding
NP805_RS20310	COG0336	Belongs to the RNA methyltransferase TrmD family
NP805_RS20315	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NP805_RS20320	COG0228	four-way junction DNA binding
NP805_RS20325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NP805_RS20330	COG4137	Cytochrome C assembly protein
NP805_RS20335	COG4536	flavin adenine dinucleotide binding
NP805_RS20340	COG1959	2 iron, 2 sulfur cluster binding
NP805_RS20345	COG1017	nitric oxide dioxygenase activity
NP805_RS20345	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
NP805_RS20350	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
NP805_RS20355	COG0039	L-malate dehydrogenase activity
NP805_RS20360	COG4160	amino acid transport
NP805_RS20380	COG4215	(ABC) transporter
NP805_RS20385	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NP805_RS20390	COG1126	abc transporter atp-binding protein
NP805_RS20395	COG1438	arginine binding
NP805_RS20400	COG2837	iron assimilation
NP805_RS20405	COG3842	ATPase activity
NP805_RS20415	COG1840	ABC-type Fe3 transport system, periplasmic component
NP805_RS20420	COG0347	Belongs to the P(II) protein family
NP805_RS20435	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
NP805_RS20440	COG0583	DNA-binding transcription factor activity
NP805_RS20455	COG1929	Belongs to the glycerate kinase type-1 family
NP805_RS20460	COG2610	gluconate transmembrane transporter activity
NP805_RS20465	COG3835	regulator
NP805_RS20470	COG3112	Uncharacterised protein family (UPF0231)
NP805_RS20485	COG0840	transmembrane signaling receptor activity
NP805_RS20490	COG3568	Endonuclease Exonuclease Phosphatase
NP805_RS20500	COG0513	Belongs to the DEAD box helicase family
NP805_RS20540	COG1448	Aminotransferase
NP805_RS20555	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NP805_RS20560	COG1328	CTP reductase activity
NP805_RS20580	COG0793	Belongs to the peptidase S41A family
NP805_RS20580	COG4946	Tricorn protease homolog
NP805_RS20595	COG1215	transferase activity, transferring glycosyl groups
NP805_RS20600	COG0726	polysaccharide deacetylase
NP805_RS20600	COG1649	PFAM Uncharacterised BCR, COG1649
NP805_RS20625	COG3397	chitin binding
NP805_RS20630	COG0583	DNA-binding transcription factor activity
NP805_RS20635	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
NP805_RS20640	COG4208	sulfate ABC transporter
NP805_RS20645	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
NP805_RS20655	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
NP805_RS20660	COG3174	membrane
NP805_RS20665	COG0110	maltose O-acetyltransferase activity
NP805_RS20695	COG1942	4-Oxalocrotonate Tautomerase
NP805_RS20705	COG0583	DNA-binding transcription factor activity
NP805_RS20710	COG0165	Argininosuccinate lyase
NP805_RS20715	COG0137	argininosuccinate synthase activity
NP805_RS20725	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NP805_RS20730	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NP805_RS20740	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NP805_RS20745	COG2072	flavoprotein involved in K transport
NP805_RS20750	COG1393	Belongs to the ArsC family
NP805_RS20755	COG0798	PFAM Bile acid sodium symporter
NP805_RS20770	COG0640	Transcriptional regulator
NP805_RS20825	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NP805_RS20850	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NP805_RS20870	COG3068	Protein conserved in bacteria
NP805_RS20880	COG0739	heme binding
NP805_RS20900	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
NP805_RS20905	COG1121	(ABC) transporter
NP805_RS20910	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NP805_RS20915	COG0583	DNA-binding transcription factor activity
NP805_RS20925	COG1573	uracil-dna glycosylase
NP805_RS20930	COG2962	Rard protein
NP805_RS20940	COG2827	Endonuclease containing a URI domain
NP805_RS20955	COG1842	Phage shock protein A
NP805_RS20960	COG0204	Acyl-transferase
NP805_RS20980	COG3118	belongs to the thioredoxin family
NP805_RS20985	COG2259	Doxx family
NP805_RS21030	COG3039	Transposase
NP805_RS21055	COG1051	belongs to the nudix hydrolase family
NP805_RS21060	COG3150	esterase
NP805_RS21070	COG3151	Protein conserved in bacteria
NP805_RS21075	COG0494	nUDIX hydrolase
NP805_RS21080	COG1538	Outer membrane efflux protein
NP805_RS21090	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NP805_RS21090	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NP805_RS21095	COG1560	Kdo2-lipid A biosynthetic process
NP805_RS21110	COG1392	Phosphate transport regulator
NP805_RS21115	COG0306	phosphate transporter
NP805_RS21120	COG0617	tRNA 3'-terminal CCA addition
NP805_RS21125	COG3267	Type II secretory pathway component ExeA
NP805_RS21125	COG3409	Peptidoglycan-binding domain 1 protein
NP805_RS21135	COG1194	a g-specific adenine glycosylase
NP805_RS21140	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
NP805_RS21150	COG3111	PFAM Bacterial OB fold (BOF) protein
NP805_RS21155	COG3240	lipase activity
NP805_RS21170	COG3009	Protein conserved in bacteria
NP805_RS21175	COG3008	intermembrane lipid transfer
NP805_RS21175	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NP805_RS21180	COG2995	paraquat-inducible protein a
NP805_RS21190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NP805_RS21200	COG3706	GGDEF domain
NP805_RS21200	COG2203	Gaf domain
NP805_RS21200	COG4251	negative regulation of phosphorylation
NP805_RS21200	COG5001	Diguanylate cyclase
NP805_RS21205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NP805_RS21210	COG2813	Specifically methylates the guanine in position
NP805_RS21215	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NP805_RS21220	COG0297	glycogen (starch) synthase activity
NP805_RS21260	COG1757	Na H antiporter
NP805_RS21280	COG0110	maltose O-acetyltransferase activity
NP805_RS21285	COG0366	Alpha amylase catalytic
NP805_RS21290	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NP805_RS21290	COG1263	PTS System
NP805_RS21310	COG0252	asparaginase activity
NP805_RS21325	COG1803	Methylglyoxal synthase
NP805_RS21350	COG1444	tRNA N-acetyltransferase activity
NP805_RS21355	COG1028	Short-chain dehydrogenase reductase Sdr
NP805_RS21360	COG0835	chemotaxis
NP805_RS21360	COG0784	Response regulator, receiver
NP805_RS21370	COG3314	Sporulation integral membrane protein YlbJ
NP805_RS21405	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NP805_RS21410	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NP805_RS21425	COG0477	Major facilitator Superfamily
NP805_RS21430	COG0523	cobalamin synthesis protein
NP805_RS21445	COG2200	EAL domain
NP805_RS21450	COG1049	propionate catabolic process, 2-methylcitrate cycle
NP805_RS21460	COG0840	transmembrane signaling receptor activity
NP805_RS21465	COG0840	transmembrane signaling receptor activity
NP805_RS21475	COG3385	transposase activity
NP805_RS21480	COG3447	MASE1 domain protein
NP805_RS21480	COG5001	Diguanylate cyclase
NP805_RS21480	COG5002	protein histidine kinase activity
NP805_RS21485	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NP805_RS21490	COG0508	dehydrogenase complex catalyzes the overall conversion of
NP805_RS21495	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NP805_RS21500	COG2186	Transcriptional regulator
NP805_RS21530	COG1459	type II secretion system
NP805_RS21535	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NP805_RS21545	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
NP805_RS21550	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
NP805_RS21555	COG3385	transposase activity
NP805_RS21560	COG0494	nUDIX hydrolase
NP805_RS21565	COG0653	protein targeting
NP805_RS21575	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
NP805_RS21580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NP805_RS21585	COG0849	cell division
NP805_RS21590	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
NP805_RS21595	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NP805_RS21600	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NP805_RS21605	COG0772	Belongs to the SEDS family
NP805_RS21610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NP805_RS21615	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NP805_RS21620	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NP805_RS21630	COG0768	penicillin binding
NP805_RS21635	COG3116	cell division
NP805_RS21640	COG0275	rRNA processing
NP805_RS21645	COG2001	Belongs to the MraZ family
NP805_RS21655	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NP805_RS21660	COG3107	peptidoglycan biosynthetic process
NP805_RS21665	COG0792	nuclease activity
NP805_RS21670	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NP805_RS21675	COG2823	Periplasmic or secreted lipoprotein
NP805_RS21680	COG2969	positive regulation of protein catabolic process
NP805_RS21685	COG0625	glutathione transferase activity
NP805_RS21690	COG2857	Cytochrome c1
NP805_RS21695	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
NP805_RS21700	COG0723	plastoquinol--plastocyanin reductase activity
NP805_RS21705	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NP805_RS21710	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NP805_RS21715	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
NP805_RS21725	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NP805_RS21730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NP805_RS21760	COG3964	amidohydrolase
NP805_RS21780	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS21785	COG1660	Displays ATPase and GTPase activities
NP805_RS21790	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS21800	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NP805_RS21805	COG1137	ATPase activity
NP805_RS21810	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
NP805_RS21815	COG3117	lipopolysaccharide transmembrane transporter activity
NP805_RS21820	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
NP805_RS21825	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
NP805_RS21825	COG0517	IMP dehydrogenase activity
NP805_RS21830	COG1127	ABC transporter
NP805_RS21835	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
NP805_RS21840	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
NP805_RS21845	COG2854	intermembrane phospholipid transfer
NP805_RS21855	COG5007	Belongs to the BolA IbaG family
NP805_RS21860	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NP805_RS21865	COG0312	modulator of DNA gyrase
NP805_RS21870	COG3028	Belongs to the UPF0307 family
NP805_RS21880	COG2926	Belongs to the UPF0265 family
NP805_RS21910	COG1396	sequence-specific DNA binding
NP805_RS21915	COG3135	benzoate transporter
NP805_RS21945	COG3047	cAMP biosynthetic process
NP805_RS21950	COG2199	diguanylate cyclase activity
NP805_RS21955	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NP805_RS21960	COG2197	response regulator
NP805_RS21975	COG3039	Transposase
NP805_RS21995	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NP805_RS22030	COG1396	sequence-specific DNA binding
NP805_RS22060	COG1278	Cold shock
NP805_RS22065	COG4771	TonB-dependent receptor
NP805_RS22070	COG3706	GGDEF domain
NP805_RS22100	COG0840	transmembrane signaling receptor activity
NP805_RS22115	COG0347	Belongs to the P(II) protein family
NP805_RS22120	COG0004	ammonium transporteR
NP805_RS22135	COG0346	lactoylglutathione lyase activity
NP805_RS22145	COG3039	Transposase
NP805_RS22155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NP805_RS22160	COG1074	ATP-dependent DNA helicase activity
NP805_RS22165	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
NP805_RS22170	COG2259	Doxx family
NP805_RS22175	COG1741	Belongs to the pirin family
NP805_RS22185	COG0583	DNA-binding transcription factor activity
NP805_RS22210	COG1176	ABC-type spermidine putrescine transport system, permease component I
NP805_RS22220	COG3842	ATPase activity
NP805_RS22230	COG2203	Gaf domain
NP805_RS22230	COG2199	diguanylate cyclase activity
NP805_RS22250	COG1247	-acetyltransferase
NP805_RS22255	COG0753	catalase activity
NP805_RS22280	COG0671	phosphoesterase, PA-phosphatase related
NP805_RS22285	COG0628	permease
NP805_RS22295	COG3284	Transcriptional regulator
NP805_RS22310	COG1461	Dihydroxyacetone kinase
NP805_RS22315	COG2376	Dihydroxyacetone kinase
NP805_RS22320	COG2252	PERMEase
NP805_RS22365	COG0203	ribosomal protein L17
NP805_RS22370	COG0202	RNA polymerase activity
NP805_RS22375	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NP805_RS22380	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
NP805_RS22385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NP805_RS22390	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NP805_RS22395	COG0201	protein transport
NP805_RS22400	COG0200	Binds to the 23S rRNA
NP805_RS22405	COG1841	ribosomal large subunit assembly
NP805_RS22410	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NP805_RS22415	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NP805_RS22420	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NP805_RS22425	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NP805_RS22430	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NP805_RS22435	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NP805_RS22440	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NP805_RS22445	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NP805_RS22450	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NP805_RS22455	COG0255	Belongs to the universal ribosomal protein uL29 family
NP805_RS22460	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NP805_RS22465	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NP805_RS22470	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NP805_RS22475	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NP805_RS22480	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NP805_RS22485	COG0089	rRNA binding
NP805_RS22490	COG0088	Forms part of the polypeptide exit tunnel
NP805_RS22495	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NP805_RS22500	COG0051	transcription antitermination factor activity, RNA binding
NP805_RS22520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NP805_RS22525	COG2183	response to ionizing radiation
NP805_RS22530	COG3385	transposase activity
NP805_RS22550	COG0596	Alpha beta hydrolase
NP805_RS22555	COG1040	competence protein
NP805_RS22560	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
NP805_RS22560	COG0316	Belongs to the HesB IscA family
NP805_RS22565	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NP805_RS22570	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
NP805_RS22575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NP805_RS22580	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NP805_RS22585	COG4942	peptidase
NP805_RS22595	COG1609	Transcriptional regulator
NP805_RS22610	COG0800	Aldolase
NP805_RS22615	COG0129	dihydroxy-acid dehydratase activity
NP805_RS22620	COG3265	gluconokinase activity
NP805_RS22625	COG2610	gluconate transmembrane transporter activity
NP805_RS22630	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NP805_RS22635	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NP805_RS22645	COG0456	acetyltransferase
NP805_RS22655	COG1490	D-aminoacyl-tRNA deacylase activity
NP805_RS22660	COG1295	ribonuclease BN
NP805_RS22665	COG1217	gtp-binding protein TYPA
NP805_RS22670	COG0174	glutamine synthetase
NP805_RS22680	COG3852	Histidine kinase
NP805_RS22685	COG2204	response regulator
NP805_RS22690	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NP805_RS22695	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NP805_RS22705	COG3078	GTPase activator activity
NP805_RS22715	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NP805_RS22725	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NP805_RS22730	COG0408	coproporphyrinogen oxidase activity
NP805_RS22735	COG0009	L-threonylcarbamoyladenylate synthase
NP805_RS22745	COG0551	DNA topoisomerase type I activity
NP805_RS22750	COG2922	Belongs to the Smg family
NP805_RS22755	COG0758	DNA mediated transformation
NP805_RS22760	COG1652	LysM domain
NP805_RS22765	COG0242	peptide deformylase activity
NP805_RS22770	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NP805_RS22775	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NP805_RS22775	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NP805_RS22780	COG0569	domain protein
NP805_RS22785	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NP805_RS22810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NP805_RS22815	COG0686	Belongs to the AlaDH PNT family
NP805_RS22820	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NP805_RS22820	COG0519	Catalyzes the synthesis of GMP from XMP
NP805_RS22830	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
NP805_RS22840	COG1012	belongs to the aldehyde dehydrogenase family
NP805_RS22860	COG2962	Rard protein
NP805_RS22870	COG1280	lysine exporter protein (LysE YggA)
NP805_RS22880	COG2391	methyltransferase activity
NP805_RS22885	COG1280	lysine exporter protein (LysE YggA)
NP805_RS22910	COG2823	Periplasmic or secreted lipoprotein
NP805_RS22930	COG3039	Transposase
NP805_RS22935	COG0210	DNA helicase
NP805_RS22940	COG1744	ABC transporter substrate-binding protein PnrA-like
NP805_RS22945	COG3845	ABC transporter
NP805_RS22950	COG4603	Belongs to the binding-protein-dependent transport system permease family
NP805_RS22955	COG1079	Belongs to the binding-protein-dependent transport system permease family
NP805_RS22965	COG0583	DNA-binding transcription factor activity
NP805_RS22985	COG1262	PFAM Formylglycine-generating sulfatase enzyme
NP805_RS22990	COG0385	Bile acid
NP805_RS22995	COG1609	Transcriptional regulator
NP805_RS23035	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
NP805_RS23040	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NP805_RS23040	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NP805_RS23045	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
NP805_RS23050	COG3074	FtsZ-dependent cytokinesis
NP805_RS23060	COG1045	serine acetyltransferase
NP805_RS23070	COG0745	RESPONSE REGULATOR receiver
NP805_RS23075	COG2205	protein histidine kinase activity
NP805_RS23080	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NP805_RS23085	COG0534	Mate efflux family protein
NP805_RS23100	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NP805_RS23105	COG2937	Belongs to the GPAT DAPAT family
NP805_RS23110	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
NP805_RS23115	COG3161	chorismate lyase activity
NP805_RS23120	COG1580	Controls the rotational direction of flagella during chemotaxis
NP805_RS23140	COG0604	alcohol dehydrogenase
NP805_RS23145	COG1609	Transcriptional regulator
NP805_RS23150	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NP805_RS23165	COG1519	Transferase
NP805_RS23170	COG0859	PFAM glycosyl transferase family 9
NP805_RS23175	COG0463	Glycosyl transferase, family 2
NP805_RS23180	COG0859	PFAM glycosyl transferase family 9
NP805_RS23185	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NP805_RS23190	COG2990	Protein conserved in bacteria
NP805_RS23195	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
NP805_RS23205	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NP805_RS23210	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NP805_RS23215	COG2003	Belongs to the UPF0758 family
NP805_RS23220	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NP805_RS23235	COG3039	Transposase
NP805_RS23240	COG0756	dUTP diphosphatase activity
NP805_RS23250	COG1309	transcriptional regulator
NP805_RS23255	COG0668	transmembrane transport
NP805_RS23265	COG0166	Belongs to the GPI family
NP805_RS23270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
NP805_RS23315	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
NP805_RS23320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NP805_RS23325	COG1739	Uncharacterized protein family UPF0029
NP805_RS23330	COG0006	proline dipeptidase activity
NP805_RS23335	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NP805_RS23340	COG1024	Enoyl-CoA hydratase
NP805_RS23340	COG1250	3-hydroxyacyl-CoA dehydrogenase
NP805_RS23345	COG0183	Belongs to the thiolase family
NP805_RS23375	COG0425	Belongs to the sulfur carrier protein TusA family
NP805_RS23380	COG0251	oxidation-reduction process
NP805_RS23390	COG2885	chlorophyll binding
NP805_RS23395	COG2818	Glycosylase
NP805_RS23400	COG0752	glycyl-tRNA synthetase alpha subunit
NP805_RS23405	COG0751	glycine-tRNA ligase activity
NP805_RS23415	COG0529	Catalyzes the synthesis of activated sulfate
NP805_RS23425	COG2199	diguanylate cyclase activity
NP805_RS23425	COG2202	Pas domain
NP805_RS23425	COG2200	EAL domain
NP805_RS23440	COG0640	Transcriptional regulator
NP805_RS23450	COG0814	amino acid
NP805_RS23455	COG0348	domain, Protein
NP805_RS23465	COG0446	pyridine nucleotide-disulphide oxidoreductase
NP805_RS23470	COG1773	rubredoxin
NP805_RS23470	COG0426	domain, Protein
NP805_RS23475	COG3604	Transcriptional regulator
NP805_RS23480	COG2188	Transcriptional regulator
NP805_RS23495	COG1609	Transcriptional regulator
NP805_RS23535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NP805_RS23560	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
NP805_RS23575	COG3118	belongs to the thioredoxin family
NP805_RS23580	COG0513	Belongs to the DEAD box helicase family
NP805_RS23585	COG0248	Ppx GppA phosphatase
NP805_RS23595	COG0742	ribosomal rna small subunit methyltransferase
NP805_RS23620	COG0805	protein transport
NP805_RS23625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
NP805_RS23635	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
NP805_RS23640	COG3165	ubiquinone biosynthetic process from chorismate
NP805_RS23650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NP805_RS23655	COG0402	S-adenosylhomocysteine deaminase activity
NP805_RS23690	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
NP805_RS23695	COG0848	biopolymer transport protein
NP805_RS23700	COG0811	peptide transport
NP805_RS23705	COG0811	peptide transport
NP805_RS23715	COG2771	luxR family
NP805_RS23720	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
NP805_RS23725	COG1349	DNA-binding transcription factor activity
NP805_RS23730	COG0745	RESPONSE REGULATOR receiver
NP805_RS23735	COG2205	protein histidine kinase activity
NP805_RS23745	COG4452	Inner membrane protein CreD
NP805_RS23750	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NP805_RS23755	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NP805_RS23760	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NP805_RS23765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NP805_RS23770	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NP805_RS23775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NP805_RS23780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NP805_RS23790	COG0356	it plays a direct role in the translocation of protons across the membrane
NP805_RS23795	COG3312	ion transport
NP805_RS23800	COG1475	DNA binding
NP805_RS23805	COG1192	Involved in chromosome partitioning
NP805_RS23810	COG0357	Ribosomal RNA small subunit methyltransferase G
NP805_RS23815	COG0445	tRNA wobble uridine modification
NP805_RS23820	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
NP805_RS23825	COG4774	siderophore transport
NP805_RS23830	COG4615	Cyclic peptide transporter
NP805_RS23835	COG1120	ATPase activity
NP805_RS23845	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NP805_RS23855	COG4774	siderophore transport
NP805_RS23860	COG4607	ABC-type enterochelin transport system periplasmic component
NP805_RS23865	COG4604	ABC transporter, ATP-binding protein
NP805_RS23870	COG4605	iron ion homeostasis
NP805_RS23875	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NP805_RS23880	COG1132	(ABC) transporter
NP805_RS23885	COG1132	(ABC) transporter
NP805_RS23885	COG2375	cellular response to nickel ion
NP805_RS23895	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NP805_RS23905	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
NP805_RS23930	COG3328	transposase activity
NP805_RS23940	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NP805_RS23945	COG0706	membrane insertase activity
NP805_RS23950	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NP805_RS23955	COG0594	ribonuclease P activity
NP805_RS23960	COG0230	Belongs to the bacterial ribosomal protein bL34 family
NP805_RS23965	COG1126	abc transporter atp-binding protein