locus-tag	class	description
G7042_RS00120	COG4695	Portal protein
G7042_RS00165	COG5002	protein histidine kinase activity
G7042_RS00165	COG2176	DNA-directed DNA polymerase activity
G7042_RS00255	COG4974	Belongs to the 'phage' integrase family
G7042_RS00260	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G7042_RS00265	COG1073	alpha beta
G7042_RS00275	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G7042_RS00280	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G7042_RS00310	COG1522	sequence-specific DNA binding
G7042_RS00310	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_RS00315	COG2313	pseudouridylate synthase activity
G7042_RS00325	COG5433	transposase activity
G7042_RS00330	COG1858	cytochrome C peroxidase
G7042_RS00375	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7042_RS00380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7042_RS00390	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_RS00405	COG2986	histidine ammonia-lyase
G7042_RS00435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_RS00445	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS00450	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_RS00460	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7042_RS00475	COG2966	Psort location CytoplasmicMembrane, score
G7042_RS00480	COG3610	response to peptide
G7042_RS00490	COG4175	Glycine betaine
G7042_RS00495	COG4176	ABC-type proline glycine betaine transport system permease component
G7042_RS00500	COG2113	Glycine betaine
G7042_RS00505	COG0175	sulfate reduction
G7042_RS00510	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7042_RS00515	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G7042_RS00520	COG0384	phenazine biosynthesis protein PhzF
G7042_RS00525	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G7042_RS00540	COG0786	glutamate:sodium symporter activity
G7042_RS00545	COG0252	asparaginase activity
G7042_RS00550	COG3139	Protein of unknown function (DUF1315)
G7042_RS00570	COG0616	signal peptide processing
G7042_RS00575	COG1902	pentaerythritol trinitrate reductase activity
G7042_RS00575	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_RS00580	COG0778	Nitroreductase
G7042_RS00600	COG4302	ethanolamine ammonia-lyase activity
G7042_RS00605	COG4303	Ethanolamine ammonia lyase large subunit
G7042_RS00610	COG0531	amino acid
G7042_RS00615	COG2264	protein methyltransferase activity
G7042_RS00620	COG0604	alcohol dehydrogenase
G7042_RS00625	COG0583	DNA-binding transcription factor activity
G7042_RS00630	COG2190	(PTS) system
G7042_RS00630	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_RS00630	COG1263	PTS System
G7042_RS00635	COG4145	pantothenate transmembrane transporter activity
G7042_RS00640	COG3924	membrane
G7042_RS00645	COG0439	Biotin carboxylase
G7042_RS00650	COG0511	ligase activity, forming carbon-carbon bonds
G7042_RS00655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G7042_RS00660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7042_RS00690	COG3381	protein complex oligomerization
G7042_RS00705	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G7042_RS00720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G7042_RS00725	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7042_RS00725	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G7042_RS00740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G7042_RS00745	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7042_RS00750	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G7042_RS00755	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G7042_RS00760	COG4172	Belongs to the ABC transporter superfamily
G7042_RS00770	COG0601	transmembrane transport
G7042_RS00780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G7042_RS00785	COG0142	geranyltranstransferase activity
G7042_RS00790	COG1722	exodeoxyribonuclease VII activity
G7042_RS00795	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G7042_RS00800	COG1360	Flagellar Motor Protein
G7042_RS00830	COG1534	Rna-binding protein
G7042_RS00835	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G7042_RS00845	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G7042_RS00850	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G7042_RS00855	COG0149	triose-phosphate isomerase activity
G7042_RS00860	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G7042_RS00875	COG0779	Required for maturation of 30S ribosomal subunits
G7042_RS00880	COG0195	Participates in both transcription termination and antitermination
G7042_RS00885	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G7042_RS00890	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G7042_RS00895	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G7042_RS00900	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G7042_RS00905	COG1185	polyribonucleotide nucleotidyltransferase activity
G7042_RS00910	COG2211	Major facilitator Superfamily
G7042_RS00915	COG3706	GGDEF domain
G7042_RS00920	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G7042_RS00925	COG1422	Protein of unknown function (DUF1090)
G7042_RS00940	COG5433	transposase activity
G7042_RS00985	COG0312	modulator of DNA gyrase
G7042_RS01000	COG4974	Belongs to the 'phage' integrase family
G7042_RS01010	COG1970	mechanosensitive ion channel activity
G7042_RS01020	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G7042_RS01035	COG3545	Serine hydrolase
G7042_RS01040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_RS01060	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G7042_RS01065	COG0321	lipoyl(octanoyl) transferase activity
G7042_RS01070	COG2921	Belongs to the UPF0250 family
G7042_RS01075	COG1686	Belongs to the peptidase S11 family
G7042_RS01080	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G7042_RS01085	COG2951	lytic endotransglycosylase activity
G7042_RS01090	COG0772	Belongs to the SEDS family
G7042_RS01095	COG0768	penicillin binding
G7042_RS01100	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G7042_RS01105	COG0799	negative regulation of ribosome biogenesis
G7042_RS01110	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G7042_RS01130	COG0495	leucyl-tRNA aminoacylation
G7042_RS01135	COG2888	peptidyl-tyrosine sulfation
G7042_RS01140	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G7042_RS01145	COG4535	Mg2 and Co2 transporter CorC
G7042_RS01150	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G7042_RS01155	COG1702	phosphate starvation-inducible protein PhoH
G7042_RS01160	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7042_RS01165	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7042_RS01175	COG3706	GGDEF domain
G7042_RS01190	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_RS01210	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7042_RS01220	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G7042_RS01230	COG0516	GMP reductase activity
G7042_RS01240	COG0642	Histidine kinase
G7042_RS01280	COG3214	Protein conserved in bacteria
G7042_RS01300	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G7042_RS01305	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G7042_RS01310	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G7042_RS01315	COG1053	succinate dehydrogenase
G7042_RS01325	COG0584	glycerophosphoryl diester phosphodiesterase
G7042_RS01355	COG0739	heme binding
G7042_RS01370	COG0583	DNA-binding transcription factor activity
G7042_RS01385	COG0840	transmembrane signaling receptor activity
G7042_RS01390	COG0583	DNA-binding transcription factor activity
G7042_RS01395	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G7042_RS01425	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G7042_RS01430	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G7042_RS01440	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G7042_RS01445	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G7042_RS01450	COG0546	phosphoglycolate phosphatase activity
G7042_RS01455	COG0180	Tryptophanyl-tRNA synthetase
G7042_RS01470	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G7042_RS01480	COG1012	belongs to the aldehyde dehydrogenase family
G7042_RS01490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_RS01510	COG0488	(ABC) transporter
G7042_RS01520	COG0366	Alpha amylase catalytic
G7042_RS01535	COG0443	Heat shock 70 kDa protein
G7042_RS01570	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
G7042_RS01580	COG0490	domain, Protein
G7042_RS01580	COG0471	metal ion transport
G7042_RS01625	COG0012	GTP binding
G7042_RS01630	COG0193	aminoacyl-tRNA hydrolase activity
G7042_RS01635	COG0737	Belongs to the 5'-nucleotidase family
G7042_RS01640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G7042_RS01650	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G7042_RS01655	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G7042_RS01660	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G7042_RS01665	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G7042_RS01670	COG2890	protein-(glutamine-N5) methyltransferase activity
G7042_RS01680	COG2912	Transglutaminase-like superfamily
G7042_RS01715	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G7042_RS01730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G7042_RS01735	COG1115	amino acid carrier protein
G7042_RS01750	COG0714	Associated with various cellular activities
G7042_RS01770	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G7042_RS01775	COG1678	Uncharacterized ACR, COG1678
G7042_RS01795	COG0189	ligase activity
G7042_RS01800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G7042_RS01810	COG3091	SprT-like family
G7042_RS01820	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G7042_RS01825	COG5433	transposase activity
G7042_RS01845	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G7042_RS01850	COG0739	heme binding
G7042_RS01855	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G7042_RS01875	COG0463	Glycosyl transferase, family 2
G7042_RS01890	COG2989	Protein conserved in bacteria
G7042_RS01895	COG3108	Peptidase M15
G7042_RS01905	COG2860	membrane
G7042_RS01915	COG1196	nuclear chromosome segregation
G7042_RS01920	COG3115	cell septum assembly
G7042_RS01925	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G7042_RS01935	COG1328	CTP reductase activity
G7042_RS01945	COG0602	queuosine metabolic process
G7042_RS01970	COG1566	PFAM secretion protein HlyD family protein
G7042_RS01975	COG1846	Transcriptional regulator
G7042_RS01990	COG0582	viral genome integration into host DNA
G7042_RS01995	COG1196	nuclear chromosome segregation
G7042_RS01995	COG3264	Mechanosensitive ion channel
G7042_RS02000	COG0469	pyruvate kinase activity
G7042_RS02015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7042_RS02015	COG4651	solute:proton antiporter activity
G7042_RS02020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7042_RS02020	COG4651	solute:proton antiporter activity
G7042_RS02025	COG0405	Gamma-glutamyltransferase
G7042_RS02030	COG2974	May be involved in recombination
G7042_RS02040	COG0420	3'-5' exonuclease activity
G7042_RS02045	COG0419	ATPase involved in DNA repair
G7042_RS02055	COG5433	transposase activity
G7042_RS02065	COG3038	cytochrome b561
G7042_RS02080	COG2190	(PTS) system
G7042_RS02090	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS02095	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G7042_RS02115	COG1720	tRNA m6t6A37 methyltransferase activity
G7042_RS02135	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G7042_RS02140	COG4988	ABC transporter
G7042_RS02155	COG0745	RESPONSE REGULATOR receiver
G7042_RS02165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G7042_RS02180	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G7042_RS02185	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
G7042_RS02195	COG0083	homoserine kinase activity
G7042_RS02200	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G7042_RS02235	COG0813	purine-nucleoside phosphorylase activity
G7042_RS02250	COG3384	dioxygenase
G7042_RS02260	COG1283	sodium-dependent phosphate transmembrane transporter activity
G7042_RS02265	COG0531	amino acid
G7042_RS02270	COG0531	amino acid
G7042_RS02285	COG1917	Cupin 2, conserved barrel domain protein
G7042_RS02285	COG1396	sequence-specific DNA binding
G7042_RS02290	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7042_RS02305	COG1917	Cupin 2, conserved barrel domain protein
G7042_RS02305	COG2169	Transcriptional regulator
G7042_RS02310	COG5433	transposase activity
G7042_RS02340	COG0840	transmembrane signaling receptor activity
G7042_RS02345	COG0835	chemotaxis
G7042_RS02365	COG0745	RESPONSE REGULATOR receiver
G7042_RS02370	COG0840	transmembrane signaling receptor activity
G7042_RS02375	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7042_RS02385	COG1280	lysine exporter protein (LysE YggA)
G7042_RS02400	COG3813	Protein conserved in bacteria
G7042_RS02410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G7042_RS02425	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G7042_RS02450	COG0300	oxidoreductase activity
G7042_RS02480	COG2133	pyrroloquinoline quinone binding
G7042_RS02505	COG1605	Chorismate mutase
G7042_RS02505	COG0077	Prephenate dehydratase
G7042_RS02535	COG3272	Protein of unknown function (DUF1722)
G7042_RS02540	COG0789	Transcriptional regulator
G7042_RS02545	COG0415	Belongs to the DNA photolyase family
G7042_RS02555	COG0300	oxidoreductase activity
G7042_RS02570	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G7042_RS02595	COG0783	Belongs to the Dps family
G7042_RS02600	COG1151	hydroxylamine reductase activity
G7042_RS02610	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7042_RS02615	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7042_RS02615	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7042_RS02625	COG3459	Glycosyltransferase 36 associated
G7042_RS02645	COG0693	protein deglycase activity
G7042_RS02650	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G7042_RS02655	COG1666	GTP binding
G7042_RS02660	COG3248	Nucleoside-binding outer membrane protein
G7042_RS02665	COG2211	Major facilitator Superfamily
G7042_RS02675	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G7042_RS02685	COG2813	Specifically methylates the guanine in position
G7042_RS02690	COG0271	Belongs to the BolA IbaG family
G7042_RS02700	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_RS02705	COG1805	sodium ion transport
G7042_RS02710	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_RS02715	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_RS02720	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G7042_RS02725	COG2871	sodium ion transport
G7042_RS02730	COG1477	protein flavinylation
G7042_RS02745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G7042_RS02750	COG0840	transmembrane signaling receptor activity
G7042_RS02755	COG0583	DNA-binding transcription factor activity
G7042_RS02765	COG2363	Small membrane protein
G7042_RS02770	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
G7042_RS02780	COG0473	3-isopropylmalate dehydrogenase activity
G7042_RS02785	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G7042_RS02790	COG1611	Belongs to the LOG family
G7042_RS02805	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7042_RS02805	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G7042_RS02815	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G7042_RS02840	COG3098	single-species biofilm formation
G7042_RS02845	COG0564	pseudouridine synthase activity
G7042_RS02855	COG5433	transposase activity
G7042_RS02860	COG4580	involved in the transport of maltose and maltodextrins
G7042_RS02870	COG1263	PTS System
G7042_RS02870	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_RS02880	COG2171	N-acyltransferase activity
G7042_RS02885	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
G7042_RS02890	COG0024	Methionine aminopeptidase
G7042_RS02895	COG0052	Belongs to the universal ribosomal protein uS2 family
G7042_RS02900	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G7042_RS02905	COG0528	UMP kinase activity
G7042_RS02910	COG0233	cytoplasmic translational termination
G7042_RS02915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G7042_RS02920	COG0575	Belongs to the CDS family
G7042_RS02925	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G7042_RS02930	COG0750	zinc metalloprotease
G7042_RS02945	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_RS02950	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7042_RS02955	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_RS02960	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_RS02965	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G7042_RS02975	COG0825	malonyl-CoA metabolic process
G7042_RS02980	COG3710	Transcriptional regulator
G7042_RS02985	COG0531	amino acid
G7042_RS02990	COG1982	Orn Lys Arg decarboxylase major
G7042_RS02995	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G7042_RS03010	COG0814	amino acid
G7042_RS03015	COG0531	amino acid
G7042_RS03025	COG0488	(ABC) transporter
G7042_RS03035	COG3590	peptidase
G7042_RS03040	COG0037	tRNA processing
G7042_RS03085	COG0366	Alpha amylase catalytic
G7042_RS03095	COG1881	PFAM PEBP family protein
G7042_RS03100	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G7042_RS03105	COG0583	DNA-binding transcription factor activity
G7042_RS03115	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G7042_RS03125	COG0583	DNA-binding transcription factor activity
G7042_RS03130	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS03135	COG0616	signal peptide processing
G7042_RS03140	COG3724	N-succinylarginine dihydrolase activity
G7042_RS03160	COG0840	transmembrane signaling receptor activity
G7042_RS03170	COG2971	BadF BadG BcrA BcrD
G7042_RS03180	COG4608	Belongs to the ABC transporter superfamily
G7042_RS03185	COG0444	Belongs to the ABC transporter superfamily
G7042_RS03190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_RS03240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G7042_RS03245	COG1289	transmembrane transporter activity
G7042_RS03250	COG0303	'Molybdopterin
G7042_RS03255	COG0746	molybdenum cofactor guanylyltransferase activity
G7042_RS03265	COG4662	Binding-protein-dependent transport system inner membrane component
G7042_RS03280	COG3852	Histidine kinase
G7042_RS03290	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G7042_RS03305	COG5433	transposase activity
G7042_RS03335	COG3383	formate dehydrogenase (NAD+) activity
G7042_RS03340	COG0437	4 iron, 4 sulfur cluster binding
G7042_RS03355	COG0281	malic enzyme
G7042_RS03365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS03385	COG0281	malic enzyme
G7042_RS03390	COG3290	protein histidine kinase activity
G7042_RS03405	COG0667	Aldo Keto reductase
G7042_RS03415	COG0697	spore germination
G7042_RS03435	COG2267	carboxylic ester hydrolase activity
G7042_RS03440	COG1942	4-Oxalocrotonate Tautomerase
G7042_RS03450	COG3284	Transcriptional regulator
G7042_RS03455	COG3706	GGDEF domain
G7042_RS03460	COG0346	lactoylglutathione lyase activity
G7042_RS03465	COG0745	RESPONSE REGULATOR receiver
G7042_RS03470	COG5002	protein histidine kinase activity
G7042_RS03490	COG1940	carbohydrate kinase activity
G7042_RS03495	COG3142	Participates in the control of copper homeostasis
G7042_RS03500	COG0545	Peptidyl-prolyl cis-trans isomerase
G7042_RS03505	COG1131	(ABC) transporter
G7042_RS03545	COG0019	diaminopimelate decarboxylase activity
G7042_RS03550	COG1115	amino acid carrier protein
G7042_RS03555	COG0095	Lipoate-protein ligase
G7042_RS03560	COG2233	PERMEase
G7042_RS03575	COG0534	Mate efflux family protein
G7042_RS03580	COG2207	Transcriptional regulator
G7042_RS03585	COG0281	malic enzyme
G7042_RS03620	COG0733	neurotransmitter:sodium symporter activity
G7042_RS03625	COG1752	Esterase of the alpha-beta hydrolase superfamily
G7042_RS03630	COG3706	GGDEF domain
G7042_RS03635	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_RS03640	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7042_RS03650	COG1032	radical SAM domain protein
G7042_RS03670	COG5433	transposase activity
G7042_RS03685	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G7042_RS03690	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7042_RS03695	COG1196	nuclear chromosome segregation
G7042_RS03695	COG0741	lytic transglycosylase activity
G7042_RS03695	COG0739	heme binding
G7042_RS03700	COG0366	Alpha amylase catalytic
G7042_RS03720	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7042_RS03730	COG0788	formyltetrahydrofolate deformylase activity
G7042_RS03735	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7042_RS03745	COG3118	belongs to the thioredoxin family
G7042_RS03750	COG2091	lysine biosynthetic process via aminoadipic acid
G7042_RS03755	COG0791	NLP P60 protein
G7042_RS03760	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
G7042_RS03775	COG1388	LysM domain
G7042_RS03775	COG1376	ErfK ybiS ycfS ynhG family protein
G7042_RS03825	COG1960	acyl-CoA dehydrogenase activity
G7042_RS03830	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7042_RS03840	COG0469	pyruvate kinase activity
G7042_RS03845	COG1737	Transcriptional regulator
G7042_RS03870	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G7042_RS03890	COG1342	Belongs to the UPF0251 family
G7042_RS03945	COG1684	flagellar biosynthetic protein fliR
G7042_RS03955	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G7042_RS03980	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G7042_RS03990	COG0450	alkyl hydroperoxide reductase
G7042_RS04010	COG0500	methyltransferase
G7042_RS04015	COG4106	trans-aconitate 2-methyltransferase activity
G7042_RS04035	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G7042_RS04040	COG0217	transcriptional regulatory protein
G7042_RS04110	COG1940	carbohydrate kinase activity
G7042_RS04110	COG1846	Transcriptional regulator
G7042_RS04115	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G7042_RS04120	COG0363	glucosamine-6-phosphate deaminase activity
G7042_RS04140	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7042_RS04145	COG0735	belongs to the Fur family
G7042_RS04155	COG0716	FMN binding
G7042_RS04170	COG0596	Alpha beta hydrolase
G7042_RS04175	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G7042_RS04180	COG0033	Phosphoglucomutase
G7042_RS04190	COG1846	Transcriptional regulator
G7042_RS04195	COG2951	lytic endotransglycosylase activity
G7042_RS04200	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G7042_RS04205	COG4136	ATPase activity
G7042_RS04210	COG4135	transport system, permease component
G7042_RS04215	COG4134	Bacterial extracellular solute-binding protein
G7042_RS04220	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7042_RS04225	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G7042_RS04235	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7042_RS04240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7042_RS04255	COG0729	surface antigen
G7042_RS04260	COG2911	Protein conserved in bacteria
G7042_RS04275	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G7042_RS04300	COG1607	acyl-coa hydrolase
G7042_RS04305	COG3021	interspecies interaction between organisms
G7042_RS04310	COG0741	lytic transglycosylase activity
G7042_RS04310	COG1388	LysM domain
G7042_RS04315	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7042_RS04320	COG2226	methyltransferase
G7042_RS04325	COG0328	RNA-DNA hybrid ribonuclease activity
G7042_RS04330	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7042_RS04340	COG0784	Response regulator, receiver
G7042_RS04340	COG3437	response regulator, receiver
G7042_RS04345	COG1960	acyl-CoA dehydrogenase activity
G7042_RS04350	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G7042_RS04355	COG0121	glutamine amidotransferase
G7042_RS04385	COG2197	response regulator
G7042_RS04390	COG3850	Histidine kinase
G7042_RS04395	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G7042_RS04400	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7042_RS04410	COG0243	molybdopterin cofactor binding
G7042_RS04415	COG0437	4 iron, 4 sulfur cluster binding
G7042_RS04420	COG0348	domain, Protein
G7042_RS04430	COG3005	denitrification pathway
G7042_RS04435	COG0521	Mo-molybdopterin cofactor biosynthetic process
G7042_RS04440	COG0315	cyclic pyranopterin monophosphate synthase activity
G7042_RS04445	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G7042_RS04450	COG0314	molybdopterin synthase activity
G7042_RS04465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G7042_RS04470	COG0596	Alpha beta hydrolase
G7042_RS04495	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G7042_RS04505	COG0302	gtp cyclohydrolase
G7042_RS04510	COG0840	transmembrane signaling receptor activity
G7042_RS04515	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G7042_RS04525	COG0583	DNA-binding transcription factor activity
G7042_RS04530	COG2353	YceI-like domain
G7042_RS04555	COG2195	Cleaves the N-terminal amino acid of tripeptides
G7042_RS04565	COG1166	arginine decarboxylase activity
G7042_RS04580	COG0346	lactoylglutathione lyase activity
G7042_RS04590	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G7042_RS04595	COG1187	pseudouridine synthase activity
G7042_RS04600	COG2807	transmembrane transport
G7042_RS04610	COG0583	DNA-binding transcription factor activity
G7042_RS04630	COG2979	Protein of unknown function (DUF533)
G7042_RS04635	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7042_RS04665	COG2814	Major facilitator Superfamily
G7042_RS04670	COG0656	L-ascorbic acid biosynthetic process
G7042_RS04675	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G7042_RS04700	COG0583	DNA-binding transcription factor activity
G7042_RS04705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G7042_RS04710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G7042_RS04715	COG2271	Major facilitator Superfamily
G7042_RS04720	COG1349	DNA-binding transcription factor activity
G7042_RS04730	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G7042_RS04735	COG0584	glycerophosphoryl diester phosphodiesterase
G7042_RS04740	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_RS04745	COG1605	Chorismate mutase
G7042_RS04745	COG0287	Prephenate dehydrogenase
G7042_RS04750	COG0583	DNA-binding transcription factor activity
G7042_RS04755	COG3085	chromosome segregation
G7042_RS04760	COG4574	serine-type endopeptidase inhibitor activity
G7042_RS04780	COG1770	oligopeptidase
G7042_RS04800	COG3083	sulfuric ester hydrolase activity
G7042_RS04805	COG3082	Protein of unknown function (DUF1414)
G7042_RS04810	COG3081	Nucleoid-associated protein
G7042_RS04815	COG2182	Extracellular solute-binding protein
G7042_RS04825	COG3833	ABC-type maltose transport systems, permease component
G7042_RS04830	COG3842	ATPase activity
G7042_RS04845	COG0628	permease
G7042_RS04850	COG0425	Belongs to the sulfur carrier protein TusA family
G7042_RS04855	COG4783	chaperone-mediated protein folding
G7042_RS04865	COG1393	Belongs to the ArsC family
G7042_RS04875	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
G7042_RS04880	COG2431	L-lysine efflux transmembrane transporter activity
G7042_RS04915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G7042_RS04925	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_RS04930	COG2373	Large extracellular alpha-helical protein
G7042_RS04935	COG4953	penicillin-binding protein 1C
G7042_RS04945	COG0301	tRNA thio-modification
G7042_RS04945	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7042_RS04960	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G7042_RS04990	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7042_RS05000	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G7042_RS05020	COG0483	inositol monophosphate 1-phosphatase activity
G7042_RS05030	COG0625	glutathione transferase activity
G7042_RS05040	COG0601	transmembrane transport
G7042_RS05045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_RS05050	COG0444	Belongs to the ABC transporter superfamily
G7042_RS05055	COG2814	Major facilitator Superfamily
G7042_RS05060	COG0583	DNA-binding transcription factor activity
G7042_RS05065	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G7042_RS05070	COG0243	molybdopterin cofactor binding
G7042_RS05090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7042_RS05095	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G7042_RS05100	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G7042_RS05105	COG0509	glycine decarboxylation via glycine cleavage system
G7042_RS05110	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7042_RS05110	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G7042_RS05125	COG3634	alkyl hydroperoxide reductase activity
G7042_RS05135	COG0517	IMP dehydrogenase activity
G7042_RS05140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G7042_RS05145	COG0343	queuine tRNA-ribosyltransferase activity
G7042_RS05150	COG1862	Preprotein translocase
G7042_RS05155	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_RS05160	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_RS05165	COG2897	thiosulfate sulfurtransferase activity
G7042_RS05175	COG0826	peptidase U32
G7042_RS05180	COG0826	peptidase U32
G7042_RS05185	COG3154	lipid carrier protein
G7042_RS05200	COG1959	2 iron, 2 sulfur cluster binding
G7042_RS05205	COG1104	cysteine desulfurase activity
G7042_RS05210	COG0822	iron-sulfur transferase activity
G7042_RS05220	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G7042_RS05225	COG0443	Heat shock 70 kDa protein
G7042_RS05230	COG0633	Ferredoxin
G7042_RS05240	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7042_RS05245	COG0105	UTP biosynthetic process
G7042_RS05250	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G7042_RS05260	COG1426	Protein conserved in bacteria
G7042_RS05265	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G7042_RS05270	COG0124	histidyl-tRNA synthetase
G7042_RS05275	COG2976	Protein conserved in bacteria
G7042_RS05280	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7042_RS05285	COG1160	GTP binding
G7042_RS05290	COG1645	bacterial-type flagellum-dependent swarming motility
G7042_RS05300	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7042_RS05305	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G7042_RS05305	COG0047	phosphoribosylformylglycinamidine synthase activity
G7042_RS05315	COG2354	Protein conserved in bacteria
G7042_RS05330	COG5433	transposase activity
G7042_RS05355	COG1242	4 iron, 4 sulfur cluster binding
G7042_RS05435	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G7042_RS05440	COG1288	antiporter activity
G7042_RS05445	COG0436	Aminotransferase
G7042_RS05455	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G7042_RS05460	COG2027	D-alanyl-D-alanine carboxypeptidase
G7042_RS05465	COG1061	Type III restriction enzyme res subunit
G7042_RS05470	COG1566	PFAM secretion protein HlyD family protein
G7042_RS05480	COG1966	Carbon starvation protein
G7042_RS05485	COG3279	Response regulator of the LytR AlgR family
G7042_RS05490	COG3275	phosphorelay sensor kinase activity
G7042_RS05510	COG1454	alcohol dehydrogenase
G7042_RS05510	COG1012	belongs to the aldehyde dehydrogenase family
G7042_RS05520	COG2095	MarC family integral membrane protein
G7042_RS05530	COG0601	transmembrane transport
G7042_RS05535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_RS05540	COG0444	Belongs to the ABC transporter superfamily
G7042_RS05555	COG0861	Integral membrane protein TerC family
G7042_RS05560	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7042_RS05570	COG1301	dicarboxylic acid transport
G7042_RS05585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G7042_RS05600	COG0537	adenosine 5'-monophosphoramidase activity
G7042_RS05635	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_RS05640	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G7042_RS05660	COG5433	transposase activity
G7042_RS05675	COG1007	ATP synthesis coupled electron transport
G7042_RS05680	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_RS05690	COG0713	ATP synthesis coupled electron transport
G7042_RS05695	COG0839	Belongs to the complex I subunit 6 family
G7042_RS05700	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_RS05705	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G7042_RS05710	COG1034	ATP synthesis coupled electron transport
G7042_RS05725	COG0649	NAD binding
G7042_RS05725	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_RS05730	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_RS05735	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_RS05740	COG1360	Flagellar Motor Protein
G7042_RS05760	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G7042_RS05775	COG4597	amino acid ABC transporter
G7042_RS05780	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS05785	COG0765	amino acid transport
G7042_RS05790	COG1126	abc transporter atp-binding protein
G7042_RS05800	COG0724	RNA recognition motif
G7042_RS05805	COG4989	oxidoreductase activity
G7042_RS05835	COG0583	DNA-binding transcription factor activity
G7042_RS05850	COG3300	MHYT domain
G7042_RS05850	COG5001	Diguanylate cyclase
G7042_RS05870	COG2814	Major facilitator Superfamily
G7042_RS05885	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G7042_RS05890	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G7042_RS05895	COG0539	negative regulation of cytoplasmic translation
G7042_RS05900	COG0776	regulation of translation
G7042_RS05910	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G7042_RS05915	COG0284	orotidine-5'-phosphate decarboxylase activity
G7042_RS05930	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G7042_RS05935	COG0602	queuosine metabolic process
G7042_RS05940	COG3530	Putative quorum-sensing-regulated virulence factor
G7042_RS05945	COG2096	Adenosyltransferase
G7042_RS05950	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7042_RS05965	COG1757	Na H antiporter
G7042_RS05970	COG1435	thymidine kinase activity
G7042_RS05990	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7042_RS06005	COG5433	transposase activity
G7042_RS06015	COG0437	4 iron, 4 sulfur cluster binding
G7042_RS06020	COG5557	Pfam Polysulphide reductase, NrfD
G7042_RS06025	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G7042_RS06030	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G7042_RS06035	COG1773	rubredoxin
G7042_RS06045	COG0601	transmembrane transport
G7042_RS06050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G7042_RS06065	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G7042_RS06070	COG0375	protein maturation
G7042_RS06075	COG0309	Hydrogenase expression formation protein (HypE)
G7042_RS06085	COG0298	carbon dioxide binding
G7042_RS06090	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G7042_RS06100	COG1921	L-seryl-tRNASec selenium transferase activity
G7042_RS06110	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G7042_RS06120	COG3260	NADH ubiquinone oxidoreductase 20
G7042_RS06125	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G7042_RS06130	COG3261	NADH dehydrogenase
G7042_RS06130	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G7042_RS06135	COG0650	Formate hydrogenlyase subunit 4
G7042_RS06140	COG0651	ATP synthesis coupled electron transport
G7042_RS06145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7042_RS06200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G7042_RS06205	COG0326	Molecular chaperone. Has ATPase activity
G7042_RS06210	COG0563	adenylate kinase activity
G7042_RS06215	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G7042_RS06220	COG3788	relative of glutathione S-transferase, MAPEG superfamily
G7042_RS06225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_RS06230	COG0840	transmembrane signaling receptor activity
G7042_RS06285	COG1021	2,3-dihydroxybenzoate-AMP ligase
G7042_RS06290	COG3433	isochorismatase activity
G7042_RS06290	COG1535	isochorismatase
G7042_RS06295	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_RS06300	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS06310	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_RS06310	COG0300	oxidoreductase activity
G7042_RS06310	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_RS06310	COG3321	synthase
G7042_RS06310	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS06315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7042_RS06320	COG2977	Belongs to the P-Pant transferase superfamily
G7042_RS06325	COG1120	ATPase activity
G7042_RS06330	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_RS06335	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_RS06340	COG4771	TonB-dependent receptor
G7042_RS06365	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
G7042_RS06365	COG0644	oxidoreductase
G7042_RS06385	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G7042_RS06390	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G7042_RS06395	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_RS06410	COG1570	exodeoxyribonuclease VII activity
G7042_RS06430	COG5433	transposase activity
G7042_RS06455	COG0516	GMP reductase activity
G7042_RS06455	COG0517	IMP dehydrogenase activity
G7042_RS06460	COG0519	Catalyzes the synthesis of GMP from XMP
G7042_RS06460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7042_RS06520	COG2062	phosphohistidine phosphatase, SixA
G7042_RS06530	COG0697	spore germination
G7042_RS06535	COG4166	transmembrane transport
G7042_RS06540	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G7042_RS06545	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G7042_RS06555	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7042_RS06560	COG1136	(ABC) transporter
G7042_RS06565	COG4591	ABC-type transport system involved in lipoprotein release permease component
G7042_RS06570	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G7042_RS06580	COG0544	peptidyl-prolyl cis-trans isomerase activity
G7042_RS06585	COG0740	serine-type endopeptidase activity
G7042_RS06590	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G7042_RS06595	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G7042_RS06600	COG0776	regulation of translation
G7042_RS06605	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G7042_RS06610	COG0488	(ABC) transporter
G7042_RS06615	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7042_RS06620	COG3162	membrane
G7042_RS06635	COG1024	Enoyl-CoA hydratase
G7042_RS06635	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7042_RS06640	COG1115	amino acid carrier protein
G7042_RS06645	COG0456	acetyltransferase
G7042_RS06655	COG1584	GPR1 FUN34 yaaH family protein
G7042_RS06685	COG1024	Enoyl-CoA hydratase
G7042_RS06690	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G7042_RS06715	COG1960	acyl-CoA dehydrogenase activity
G7042_RS06720	COG1024	Enoyl-CoA hydratase
G7042_RS06725	COG1024	Enoyl-CoA hydratase
G7042_RS06735	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS06745	COG0730	response to heat
G7042_RS06775	COG2378	regulation of single-species biofilm formation
G7042_RS06785	COG0140	phosphoribosyl-ATP diphosphatase activity
G7042_RS06785	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G7042_RS06790	COG0107	imidazoleglycerol-phosphate synthase activity
G7042_RS06795	COG0784	Response regulator, receiver
G7042_RS06795	COG2198	Histidine kinase
G7042_RS06795	COG2205	protein histidine kinase activity
G7042_RS06800	COG2199	diguanylate cyclase activity
G7042_RS06805	COG3437	response regulator, receiver
G7042_RS06810	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G7042_RS06815	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G7042_RS06820	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7042_RS06820	COG0131	Imidazoleglycerol-phosphate dehydratase
G7042_RS06825	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G7042_RS06830	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G7042_RS06835	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G7042_RS06845	COG1199	ATP-dependent helicase activity
G7042_RS06850	COG1214	PFAM Peptidase M22, glycoprotease
G7042_RS06860	COG2267	carboxylic ester hydrolase activity
G7042_RS06865	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_RS06885	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7042_RS06890	COG2832	Protein of unknown function (DUF454)
G7042_RS06895	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G7042_RS06900	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G7042_RS06905	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G7042_RS06910	COG3314	Sporulation integral membrane protein YlbJ
G7042_RS06915	COG2197	response regulator
G7042_RS06920	COG0617	tRNA 3'-terminal CCA addition
G7042_RS06920	COG0517	IMP dehydrogenase activity
G7042_RS06920	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G7042_RS06925	COG1643	Atp-dependent helicase
G7042_RS06935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G7042_RS06940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G7042_RS06945	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G7042_RS06950	COG0709	Synthesizes selenophosphate from selenide and ATP
G7042_RS06965	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7042_RS06975	COG1254	Belongs to the acylphosphatase family
G7042_RS06980	COG0625	glutathione transferase activity
G7042_RS06985	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_RS06985	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_RS06990	COG0489	protein tyrosine kinase activity
G7042_RS06995	COG0572	uridine kinase
G7042_RS07000	COG0717	Belongs to the dCTP deaminase family
G7042_RS07005	COG0306	phosphate transporter
G7042_RS07010	COG1530	ribonuclease E activity
G7042_RS07020	COG0546	phosphoglycolate phosphatase activity
G7042_RS07030	COG1399	metal-binding, possibly nucleic acid-binding protein
G7042_RS07035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G7042_RS07040	COG0416	fatty acid biosynthetic process
G7042_RS07045	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G7042_RS07055	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS07060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G7042_RS07065	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_RS07070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G7042_RS07075	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G7042_RS07080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G7042_RS07085	COG0470	DNA polymerase III
G7042_RS07090	COG0084	hydrolase, TatD family'
G7042_RS07105	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
G7042_RS07105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7042_RS07115	COG2995	paraquat-inducible protein a
G7042_RS07125	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G7042_RS07130	COG0372	Belongs to the citrate synthase family
G7042_RS07175	COG4221	oxidoreductase activity
G7042_RS07205	COG3620	sequence-specific DNA binding
G7042_RS07265	COG5433	transposase activity
G7042_RS07445	COG0741	lytic transglycosylase activity
G7042_RS07480	COG2003	Belongs to the UPF0758 family
G7042_RS07575	COG1067	ATP-dependent peptidase activity
G7042_RS07580	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G7042_RS07595	COG0488	(ABC) transporter
G7042_RS07605	COG0116	Belongs to the methyltransferase superfamily
G7042_RS07605	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G7042_RS07620	COG0167	dihydroorotate dehydrogenase activity
G7042_RS07630	COG5433	transposase activity
G7042_RS07645	COG0308	aminopeptidase N
G7042_RS07655	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G7042_RS07660	COG1956	GAF domain-containing protein
G7042_RS07670	COG3278	Belongs to the heme-copper respiratory oxidase family
G7042_RS07685	COG2010	Cytochrome c
G7042_RS07695	COG2217	Heavy metal translocating P-type atpase
G7042_RS07710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7042_RS07715	COG0589	response to stress
G7042_RS07720	COG0037	tRNA processing
G7042_RS07740	COG1869	D-ribose catabolic process
G7042_RS07750	COG1172	Belongs to the binding-protein-dependent transport system permease family
G7042_RS07755	COG1879	ABC-type sugar transport system periplasmic component
G7042_RS07760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_RS07765	COG1609	Transcriptional regulator
G7042_RS07810	COG0776	regulation of translation
G7042_RS07815	COG0072	phenylalanine-tRNA ligase activity
G7042_RS07815	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_RS07820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G7042_RS07825	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G7042_RS07830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G7042_RS07835	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G7042_RS07840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G7042_RS07865	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7042_RS07875	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7042_RS07880	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7042_RS07885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7042_RS07890	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G7042_RS07895	COG3313	Fe-S protein
G7042_RS07900	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G7042_RS07900	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_RS07900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_RS07905	COG1105	Belongs to the carbohydrate kinase PfkB family
G7042_RS07910	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS07910	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS07915	COG1609	Transcriptional regulator
G7042_RS07920	COG0814	amino acid
G7042_RS07930	COG5654	RES domain protein
G7042_RS07935	COG0513	Belongs to the DEAD box helicase family
G7042_RS07945	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G7042_RS07950	COG2890	protein-(glutamine-N5) methyltransferase activity
G7042_RS07955	COG2840	Smr protein MutS2
G7042_RS07960	COG3706	GGDEF domain
G7042_RS08010	COG2824	Alkylphosphonate utilization operon protein PhnA
G7042_RS08015	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7042_RS08015	COG1024	Enoyl-CoA hydratase
G7042_RS08020	COG0183	Belongs to the thiolase family
G7042_RS08025	COG0714	Associated with various cellular activities
G7042_RS08065	COG2067	long-chain fatty acid transport protein
G7042_RS08070	COG2067	long-chain fatty acid transport protein
G7042_RS08075	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G7042_RS08095	COG3123	guanosine phosphorylase activity
G7042_RS08100	COG1760	l-serine dehydratase
G7042_RS08105	COG1760	l-serine dehydratase
G7042_RS08110	COG2951	lytic endotransglycosylase activity
G7042_RS08115	COG3100	YcgL domain-containing protein
G7042_RS08120	COG0850	regulation of cytokinetic process
G7042_RS08125	COG2894	cell division
G7042_RS08130	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G7042_RS08135	COG3099	Belongs to the UPF0263 family
G7042_RS08140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7042_RS08185	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G7042_RS08190	COG0697	spore germination
G7042_RS08195	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G7042_RS08200	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_RS08210	COG0307	riboflavin synthase, alpha
G7042_RS08220	COG0534	Mate efflux family protein
G7042_RS08255	COG0417	DNA replication proofreading
G7042_RS08285	COG1560	Kdo2-lipid A biosynthetic process
G7042_RS08295	COG0583	DNA-binding transcription factor activity
G7042_RS08300	COG0673	inositol 2-dehydrogenase activity
G7042_RS08305	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G7042_RS08310	COG0583	DNA-binding transcription factor activity
G7042_RS08320	COG2723	6-phospho-beta-galactosidase activity
G7042_RS08325	COG0583	DNA-binding transcription factor activity
G7042_RS08355	COG3134	Outer membrane lipoprotein
G7042_RS08375	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_RS08395	COG4681	YaeQ
G7042_RS08430	COG0242	peptide deformylase activity
G7042_RS08455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G7042_RS08460	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G7042_RS08465	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G7042_RS08475	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G7042_RS08485	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G7042_RS08495	COG0205	6-phosphofructokinase activity
G7042_RS08535	COG1011	Hydrolase
G7042_RS08590	COG3593	DNA synthesis involved in DNA repair
G7042_RS08605	COG0583	DNA-binding transcription factor activity
G7042_RS08610	COG0730	response to heat
G7042_RS08615	COG3148	PFAM DTW domain containing protein
G7042_RS08625	COG1181	Belongs to the D-alanine--D-alanine ligase family
G7042_RS08635	COG0386	Belongs to the glutathione peroxidase family
G7042_RS08640	COG0513	Belongs to the DEAD box helicase family
G7042_RS08655	COG1742	UPF0060 membrane protein
G7042_RS08695	COG2329	Antibiotic biosynthesis monooxygenase
G7042_RS08700	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G7042_RS08720	COG3243	poly(R)-hydroxyalkanoic acid synthase
G7042_RS08730	COG2501	S4 domain
G7042_RS08740	COG1132	(ABC) transporter
G7042_RS08755	COG3118	belongs to the thioredoxin family
G7042_RS08760	COG0471	metal ion transport
G7042_RS08765	COG0058	SHG alpha-glucan phosphorylase activity
G7042_RS08810	COG5433	transposase activity
G7042_RS08835	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7042_RS08845	COG0814	amino acid
G7042_RS08850	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G7042_RS08855	COG0514	ATP-dependent DNA helicase (RecQ)
G7042_RS08860	COG2766	serine protein kinase
G7042_RS08870	COG2719	SpoVR family
G7042_RS08875	COG2186	Transcriptional regulator
G7042_RS08880	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7042_RS08885	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G7042_RS08890	COG0586	Pfam SNARE associated Golgi protein
G7042_RS08900	COG0556	nucleotide-excision repair
G7042_RS08910	COG2985	domain, Protein
G7042_RS08910	COG0569	domain protein
G7042_RS08915	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7042_RS08920	COG5433	transposase activity
G7042_RS08950	COG4565	transcriptional regulatory protein
G7042_RS08955	COG3290	protein histidine kinase activity
G7042_RS08960	COG1846	Transcriptional regulator
G7042_RS08960	COG1940	carbohydrate kinase activity
G7042_RS08965	COG0840	transmembrane signaling receptor activity
G7042_RS08970	COG3012	SEC-C Motif Domain Protein
G7042_RS08975	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G7042_RS08980	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G7042_RS08985	COG0247	lactate metabolic process
G7042_RS08995	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G7042_RS09000	COG0437	4 iron, 4 sulfur cluster binding
G7042_RS09005	COG3301	Polysulphide reductase, NrfD
G7042_RS09020	COG4235	cytochrome complex assembly
G7042_RS09020	COG3088	subunit of a heme lyase
G7042_RS09035	COG3033	Beta-eliminating lyase
G7042_RS09045	COG3046	protein related to deoxyribodipyrimidine photolyase
G7042_RS09075	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G7042_RS09080	COG0583	DNA-binding transcription factor activity
G7042_RS09090	COG4774	siderophore transport
G7042_RS09095	COG3708	Transcriptional regulator
G7042_RS09095	COG2207	Transcriptional regulator
G7042_RS09105	COG0583	DNA-binding transcription factor activity
G7042_RS09110	COG2910	NAD(P)H-binding
G7042_RS09130	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7042_RS09135	COG1944	ATP diphosphatase activity
G7042_RS09140	COG2116	formate transmembrane transporter activity
G7042_RS09145	COG1882	Formate acetyltransferase
G7042_RS09150	COG2983	Belongs to the UPF0260 family
G7042_RS09155	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G7042_RS09160	COG0045	succinate-CoA ligase (ADP-forming) activity
G7042_RS09165	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7042_RS09170	COG0567	Dehydrogenase, E1 component
G7042_RS09180	COG1053	succinate dehydrogenase
G7042_RS09185	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G7042_RS09210	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G7042_RS09215	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G7042_RS09215	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7042_RS09225	COG3069	C4-dicarboxylate transmembrane transporter activity
G7042_RS09240	COG1451	nucleotide metabolic process
G7042_RS09255	COG0254	rRNA binding
G7042_RS09260	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7042_RS09280	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G7042_RS09285	COG3833	ABC-type maltose transport systems, permease component
G7042_RS09345	COG4580	involved in the transport of maltose and maltodextrins
G7042_RS09350	COG1609	Transcriptional regulator
G7042_RS09355	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7042_RS09375	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G7042_RS09385	COG1172	Belongs to the binding-protein-dependent transport system permease family
G7042_RS09390	COG1129	ABC transporter
G7042_RS09395	COG1879	ABC-type sugar transport system periplasmic component
G7042_RS09400	COG1069	ribulokinase activity
G7042_RS09410	COG2160	L-arabinose isomerase activity
G7042_RS09415	COG0583	DNA-binding transcription factor activity
G7042_RS09420	COG0436	Aminotransferase
G7042_RS09425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7042_RS09440	COG2925	Exonuclease
G7042_RS09450	COG3345	alpha-galactosidase
G7042_RS09460	COG1380	Effector of murein hydrolase LrgA
G7042_RS09465	COG1346	cytolysis
G7042_RS09470	COG0295	cytidine deaminase activity
G7042_RS09475	COG1022	Amp-dependent synthetase and ligase
G7042_RS09490	COG0861	Integral membrane protein TerC family
G7042_RS09500	COG2199	diguanylate cyclase activity
G7042_RS09515	COG2154	pterin-4-alpha-carbinolamine dehydratase
G7042_RS09525	COG3768	UPF0283 membrane protein
G7042_RS09530	COG3106	COG3106 Predicted ATPase
G7042_RS09545	COG1842	Phage shock protein A
G7042_RS09550	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
G7042_RS09560	COG4168	peptide transport system, permease
G7042_RS09565	COG4171	peptide transport system, permease
G7042_RS09570	COG4172	Belongs to the ABC transporter superfamily
G7042_RS09575	COG4172	Belongs to the ABC transporter superfamily
G7042_RS09585	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G7042_RS09590	COG1286	toxin biosynthetic process
G7042_RS09595	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G7042_RS09600	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G7042_RS09605	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G7042_RS09610	COG0531	amino acid
G7042_RS09610	COG1674	ftsk spoiiie
G7042_RS09630	COG0492	ferredoxin-NADP+ reductase activity
G7042_RS09640	COG3134	Outer membrane lipoprotein
G7042_RS09645	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G7042_RS09650	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G7042_RS09655	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G7042_RS09660	COG0542	response to heat
G7042_RS09665	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G7042_RS09670	COG1278	Cold shock
G7042_RS09675	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G7042_RS09735	COG3829	transcription factor binding
G7042_RS09805	COG0659	secondary active sulfate transmembrane transporter activity
G7042_RS09855	COG0697	spore germination
G7042_RS09860	COG4657	Part of a membrane complex involved in electron transport
G7042_RS09865	COG2878	Part of a membrane complex involved in electron transport
G7042_RS09875	COG4658	electron transport chain
G7042_RS09880	COG4659	FMN binding
G7042_RS09885	COG4660	Part of a membrane complex involved in electron transport
G7042_RS09890	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G7042_RS09895	COG0346	lactoylglutathione lyase activity
G7042_RS09910	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G7042_RS09915	COG2056	Na+-H+ antiporter family
G7042_RS09920	COG5001	Diguanylate cyclase
G7042_RS09920	COG3300	MHYT domain
G7042_RS09930	COG0513	Belongs to the DEAD box helicase family
G7042_RS09935	COG2050	protein possibly involved in aromatic compounds catabolism
G7042_RS09945	COG0277	FAD linked oxidase domain protein
G7042_RS09945	COG0247	lactate metabolic process
G7042_RS09955	COG1253	flavin adenine dinucleotide binding
G7042_RS09960	COG1902	pentaerythritol trinitrate reductase activity
G7042_RS09970	COG0647	UMP catabolic process
G7042_RS09975	COG4651	solute:proton antiporter activity
G7042_RS09975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G7042_RS09985	COG0367	asparagine synthase
G7042_RS10010	COG0625	glutathione transferase activity
G7042_RS10015	COG0625	glutathione transferase activity
G7042_RS10040	COG0564	pseudouridine synthase activity
G7042_RS10060	COG0840	transmembrane signaling receptor activity
G7042_RS10070	COG0670	Belongs to the BI1 family
G7042_RS10075	COG1289	transmembrane transporter activity
G7042_RS10080	COG2920	part of a sulfur-relay system
G7042_RS10085	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G7042_RS10090	COG0285	dihydrofolate synthase activity
G7042_RS10095	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G7042_RS10100	COG0101	tRNA pseudouridine synthase activity
G7042_RS10110	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G7042_RS10115	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7042_RS10120	COG0671	phosphoesterase, PA-phosphatase related
G7042_RS10140	COG5433	transposase activity
G7042_RS10175	COG0574	Belongs to the PEP-utilizing enzyme family
G7042_RS10175	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7042_RS10240	COG0672	)-iron permease
G7042_RS10265	COG2814	Major facilitator Superfamily
G7042_RS10280	COG1136	(ABC) transporter
G7042_RS10285	COG0577	efflux transmembrane transporter activity
G7042_RS10300	COG1285	pathogenesis
G7042_RS10355	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G7042_RS10360	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G7042_RS10360	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7042_RS10365	COG0527	aspartate kinase activity
G7042_RS10375	COG1368	sulfuric ester hydrolase activity
G7042_RS10380	COG1619	proteins homologs of microcin C7 resistance protein MccF
G7042_RS10390	COG0393	Putative heavy-metal-binding
G7042_RS10395	COG1252	NADH dehydrogenase
G7042_RS10430	COG0789	Transcriptional regulator
G7042_RS10445	COG0493	'glutamate synthase
G7042_RS10450	COG0069	glutamate synthase activity
G7042_RS10450	COG0067	glutamate synthase
G7042_RS10450	COG0070	glutamate synthase
G7042_RS10455	COG5433	transposase activity
G7042_RS10505	COG0513	Belongs to the DEAD box helicase family
G7042_RS10510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_RS10540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7042_RS10545	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G7042_RS10550	COG0505	Belongs to the CarA family
G7042_RS10555	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G7042_RS10570	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G7042_RS10575	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G7042_RS10580	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G7042_RS10585	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G7042_RS10590	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_RS10595	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
G7042_RS10605	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS10605	COG2205	protein histidine kinase activity
G7042_RS10650	COG2119	membrane
G7042_RS10680	COG2203	Gaf domain
G7042_RS10680	COG2199	diguanylate cyclase activity
G7042_RS10705	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G7042_RS10715	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G7042_RS10720	COG2261	transglycosylase associated protein
G7042_RS10760	COG0322	excinuclease ABC activity
G7042_RS10765	COG2197	response regulator
G7042_RS10770	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G7042_RS10775	COG2835	tetraacyldisaccharide 4'-kinase activity
G7042_RS10780	COG1663	tetraacyldisaccharide 4'-kinase activity
G7042_RS10785	COG1132	(ABC) transporter
G7042_RS10790	COG2333	competence protein COMEC
G7042_RS10790	COG0658	competence protein
G7042_RS10805	COG0433	COG0433 Predicted ATPase
G7042_RS10810	COG1448	Aminotransferase
G7042_RS10825	COG1199	ATP-dependent helicase activity
G7042_RS10840	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G7042_RS10845	COG1785	Belongs to the alkaline phosphatase family
G7042_RS10865	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7042_RS10880	COG2271	Major facilitator Superfamily
G7042_RS10885	COG3706	GGDEF domain
G7042_RS10890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS10895	COG0765	amino acid transport
G7042_RS10900	COG1126	abc transporter atp-binding protein
G7042_RS10910	COG0531	amino acid
G7042_RS10925	COG1253	flavin adenine dinucleotide binding
G7042_RS10930	COG0704	Plays a role in the regulation of phosphate uptake
G7042_RS10935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G7042_RS10940	COG0581	inorganic phosphate transmembrane transporter activity
G7042_RS10945	COG0573	inorganic phosphate transmembrane transporter activity
G7042_RS10950	COG0590	tRNA wobble adenosine to inosine editing
G7042_RS10960	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G7042_RS10980	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G7042_RS10985	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G7042_RS10990	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G7042_RS10995	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G7042_RS11025	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G7042_RS11030	COG0248	Ppx GppA phosphatase
G7042_RS11035	COG2239	Acts as a magnesium transporter
G7042_RS11070	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G7042_RS11080	COG4787	bacterial-type flagellum-dependent cell motility
G7042_RS11100	COG1815	bacterial-type flagellum-dependent cell motility
G7042_RS11105	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G7042_RS11110	COG0784	Response regulator, receiver
G7042_RS11110	COG0835	chemotaxis
G7042_RS11130	COG0622	Phosphoesterase
G7042_RS11135	COG4166	transmembrane transport
G7042_RS11160	COG0697	spore germination
G7042_RS11200	COG1278	Cold shock
G7042_RS11255	COG3132	Protein of unknown function, DUF480
G7042_RS11270	COG5433	transposase activity
G7042_RS11295	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7042_RS11310	COG5433	transposase activity
G7042_RS11320	COG3273	potassium ion transport
G7042_RS11320	COG0471	metal ion transport
G7042_RS11325	COG5433	transposase activity
G7042_RS11345	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G7042_RS11350	COG0438	transferase activity, transferring glycosyl groups
G7042_RS11370	COG1450	Type ii and iii secretion system protein
G7042_RS11415	COG1459	type II secretion system
G7042_RS11420	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7042_RS11440	COG1091	dTDP-4-dehydrorhamnose reductase activity
G7042_RS11465	COG1309	transcriptional regulator
G7042_RS11480	COG1946	Acyl-CoA thioesterase
G7042_RS11490	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G7042_RS11500	COG0009	L-threonylcarbamoyladenylate synthase
G7042_RS11515	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G7042_RS11520	COG0512	Glutamine amidotransferase of anthranilate synthase
G7042_RS11520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7042_RS11525	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G7042_RS11530	COG0135	phosphoribosylanthranilate isomerase activity
G7042_RS11530	COG0134	indole-3-glycerol-phosphate synthase activity
G7042_RS11535	COG0133	tryptophan synthase activity
G7042_RS11540	COG0159	tryptophan synthase activity
G7042_RS11590	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS11590	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_RS11590	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_RS11600	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_RS11620	COG0482	sulfurtransferase activity
G7042_RS11625	COG2915	High frequency lysogenization protein hflD homolog
G7042_RS11630	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G7042_RS11635	COG2850	peptidyl-arginine hydroxylation
G7042_RS11670	COG0259	pyridoxamine-phosphate oxidase activity
G7042_RS11685	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7042_RS11685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7042_RS11690	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G7042_RS11710	COG4235	cytochrome complex assembly
G7042_RS11710	COG3088	subunit of a heme lyase
G7042_RS11715	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G7042_RS11720	COG1138	Cytochrome C-type biogenesis protein
G7042_RS11725	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G7042_RS11730	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7042_RS11735	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7042_RS11740	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G7042_RS11760	COG0835	chemotaxis
G7042_RS11770	COG1192	Involved in chromosome partitioning
G7042_RS11775	COG1360	Flagellar Motor Protein
G7042_RS11780	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G7042_RS11785	COG2201	protein-glutamate methylesterase activity
G7042_RS11790	COG2198	Histidine kinase
G7042_RS11790	COG0643	Histidine kinase
G7042_RS11790	COG0784	Response regulator, receiver
G7042_RS11800	COG0583	DNA-binding transcription factor activity
G7042_RS11810	COG0791	NLP P60 protein
G7042_RS11825	COG1309	transcriptional regulator
G7042_RS11865	COG0534	Mate efflux family protein
G7042_RS11875	COG2841	Protein conserved in bacteria
G7042_RS11880	COG0674	pyruvate-flavodoxin oxidoreductase activity
G7042_RS11880	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G7042_RS11880	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G7042_RS11880	COG1013	pyruvate-flavodoxin oxidoreductase activity
G7042_RS11895	COG3217	Mosc domain protein beta barrel domain protein
G7042_RS11895	COG0633	Ferredoxin
G7042_RS11895	COG0633	Ferredoxin
G7042_RS11895	COG3217	Mosc domain protein beta barrel domain protein
G7042_RS11905	COG0501	Belongs to the peptidase M48B family
G7042_RS11910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G7042_RS11915	COG2226	methyltransferase
G7042_RS11915	COG1073	alpha beta
G7042_RS11920	COG0156	8-amino-7-oxononanoate synthase activity
G7042_RS11925	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G7042_RS11945	COG0017	Asparaginyl-tRNA synthetase
G7042_RS11965	COG0583	DNA-binding transcription factor activity
G7042_RS11970	COG1393	Belongs to the ArsC family
G7042_RS11975	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G7042_RS11980	COG1876	peptidase activity
G7042_RS11990	COG3263	regulation of cellular component size
G7042_RS12010	COG5433	transposase activity
G7042_RS12020	COG1280	lysine exporter protein (LysE YggA)
G7042_RS12025	COG0840	transmembrane signaling receptor activity
G7042_RS12045	COG1957	nucleoside hydrolase
G7042_RS12060	COG1454	alcohol dehydrogenase
G7042_RS12100	COG2894	cell division
G7042_RS12110	COG4964	Belongs to the GSP D family
G7042_RS12140	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7042_RS12145	COG0702	epimerase
G7042_RS12150	COG2914	Belongs to the UPF0125 (RnfH) family
G7042_RS12155	COG2867	negative regulation of translational initiation
G7042_RS12165	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G7042_RS12175	COG0582	viral genome integration into host DNA
G7042_RS12220	COG0538	isocitrate dehydrogenase activity
G7042_RS12225	COG2207	Transcriptional regulator
G7042_RS12240	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G7042_RS12255	COG5433	transposase activity
G7042_RS12275	COG1263	PTS System
G7042_RS12275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_RS12280	COG1609	Transcriptional regulator
G7042_RS12315	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G7042_RS12320	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G7042_RS12325	COG1845	cytochrome c oxidase, subunit III
G7042_RS12330	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G7042_RS12335	COG0109	protoheme IX farnesyltransferase activity
G7042_RS12340	COG2814	Major facilitator Superfamily
G7042_RS12395	COG0708	Exodeoxyribonuclease III
G7042_RS12435	COG0095	Lipoate-protein ligase
G7042_RS12480	COG1285	pathogenesis
G7042_RS12510	COG0484	heat shock protein binding
G7042_RS12515	COG0443	Heat shock 70 kDa protein
G7042_RS12520	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G7042_RS12525	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G7042_RS12530	COG0497	DNA recombination
G7042_RS12540	COG1227	inorganic diphosphatase activity
G7042_RS12550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_RS12555	COG1136	(ABC) transporter
G7042_RS12555	COG0577	efflux transmembrane transporter activity
G7042_RS12560	COG1538	Outer membrane efflux protein
G7042_RS12565	COG2375	cellular response to nickel ion
G7042_RS12570	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G7042_RS12575	COG3328	transposase activity
G7042_RS12580	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7042_RS12605	COG2201	protein-glutamate methylesterase activity
G7042_RS12610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7042_RS12655	COG2203	Gaf domain
G7042_RS12655	COG2200	EAL domain
G7042_RS12655	COG2199	diguanylate cyclase activity
G7042_RS12660	COG0826	peptidase U32
G7042_RS12665	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G7042_RS12670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G7042_RS12685	COG2200	EAL domain
G7042_RS12690	COG0737	Belongs to the 5'-nucleotidase family
G7042_RS12710	COG2204	response regulator
G7042_RS12715	COG0545	Peptidyl-prolyl cis-trans isomerase
G7042_RS12730	COG1047	Peptidyl-prolyl cis-trans
G7042_RS12735	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G7042_RS12745	COG0835	chemotaxis
G7042_RS12745	COG0784	Response regulator, receiver
G7042_RS12750	COG0429	hydrolase of the alpha beta-hydrolase fold
G7042_RS12755	COG4251	negative regulation of phosphorylation
G7042_RS12755	COG5001	Diguanylate cyclase
G7042_RS12755	COG3706	GGDEF domain
G7042_RS12755	COG2203	Gaf domain
G7042_RS12760	COG3089	Belongs to the UPF0270 family
G7042_RS12785	COG0463	Glycosyl transferase, family 2
G7042_RS12795	COG0726	polysaccharide deacetylase
G7042_RS12800	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G7042_RS12805	COG2076	Multidrug Resistance protein
G7042_RS12815	COG3954	Phosphoribulokinase
G7042_RS12830	COG1765	OsmC-like protein
G7042_RS12845	COG3397	chitin binding
G7042_RS12890	COG0748	coenzyme F420 binding
G7042_RS12895	COG3721	Heme iron utilization protein
G7042_RS12905	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_RS12930	COG0488	(ABC) transporter
G7042_RS12940	COG2252	PERMEase
G7042_RS12945	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G7042_RS12950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G7042_RS12955	COG3178	'Phosphotransferase
G7042_RS12960	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G7042_RS12970	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G7042_RS12975	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G7042_RS12980	COG2967	ApaG domain
G7042_RS12985	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G7042_RS13000	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G7042_RS13020	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_RS13025	COG3314	Sporulation integral membrane protein YlbJ
G7042_RS13030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G7042_RS13035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G7042_RS13040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G7042_RS13045	COG0142	geranyltranstransferase activity
G7042_RS13050	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G7042_RS13055	COG0330	HflC and HflK could
G7042_RS13060	COG0330	HflC and HflK could
G7042_RS13065	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G7042_RS13070	COG1923	regulation of RNA biosynthetic process
G7042_RS13075	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G7042_RS13080	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G7042_RS13090	COG0802	atpase or kinase
G7042_RS13095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G7042_RS13095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G7042_RS13115	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G7042_RS13120	COG2011	ABC-type metal ion transport system permease component
G7042_RS13125	COG1464	Belongs to the NlpA lipoprotein family
G7042_RS13135	COG0840	transmembrane signaling receptor activity
G7042_RS13160	COG2198	Histidine kinase
G7042_RS13160	COG5002	protein histidine kinase activity
G7042_RS13160	COG0784	Response regulator, receiver
G7042_RS13195	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G7042_RS13200	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G7042_RS13210	COG2716	regulation of RNA biosynthetic process
G7042_RS13215	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G7042_RS13220	COG3013	Belongs to the UPF0304 family
G7042_RS13230	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G7042_RS13235	COG0280	phosphate acetyltransferase
G7042_RS13235	COG0857	belongs to the CobB CobQ family
G7042_RS13240	COG0440	acetolactate synthase activity
G7042_RS13245	COG0028	Belongs to the TPP enzyme family
G7042_RS13260	COG0671	phosphoesterase, PA-phosphatase related
G7042_RS13270	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G7042_RS13275	COG0473	3-isopropylmalate dehydrogenase activity
G7042_RS13280	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G7042_RS13285	COG0066	3-isopropylmalate dehydratase activity
G7042_RS13300	COG4143	(ABC) transporter
G7042_RS13305	COG1178	ABC-type Fe3 transport system permease component
G7042_RS13310	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G7042_RS13315	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G7042_RS13325	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G7042_RS13355	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7042_RS13360	COG0564	pseudouridine synthase activity
G7042_RS13370	COG3300	MHYT domain
G7042_RS13370	COG5001	Diguanylate cyclase
G7042_RS13380	COG0459	protein refolding
G7042_RS13385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G7042_RS13390	COG0534	Mate efflux family protein
G7042_RS13395	COG3030	protein affecting phage T7 exclusion by the F plasmid
G7042_RS13400	COG1027	Aspartate ammonia-lyase
G7042_RS13405	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G7042_RS13415	COG0477	Major facilitator Superfamily
G7042_RS13425	COG3227	Zinc metalloprotease (Elastase)
G7042_RS13430	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_RS13435	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G7042_RS13450	COG0673	inositol 2-dehydrogenase activity
G7042_RS13460	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G7042_RS13465	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7042_RS13470	COG3036	rescue of stalled ribosome
G7042_RS13475	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G7042_RS13485	COG0138	bifunctional purine biosynthesis protein purh
G7042_RS13490	COG0151	Belongs to the GarS family
G7042_RS13530	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G7042_RS13535	COG0358	DNA primase activity
G7042_RS13540	COG1610	YqeY-like protein
G7042_RS13545	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G7042_RS13550	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G7042_RS13560	COG4942	peptidase
G7042_RS13560	COG1388	LysM domain
G7042_RS13565	COG1238	metal cluster binding
G7042_RS13570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G7042_RS13575	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G7042_RS13580	COG0585	pseudouridine synthase activity
G7042_RS13590	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G7042_RS13595	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G7042_RS13600	COG0148	phosphopyruvate hydratase activity
G7042_RS13605	COG0504	CTP synthase activity
G7042_RS13610	COG3956	TIGRFAM MazG family protein
G7042_RS13615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7042_RS13620	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7042_RS13630	COG4807	Protein conserved in bacteria
G7042_RS13635	COG3023	N-Acetylmuramoyl-L-alanine amidase
G7042_RS13640	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G7042_RS13645	COG1381	Involved in DNA repair and RecF pathway recombination
G7042_RS13655	COG0571	ribonuclease III activity
G7042_RS13665	COG0481	GTPase activity
G7042_RS13680	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
G7042_RS13685	COG1595	DNA-templated transcription, initiation
G7042_RS13690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G7042_RS13740	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G7042_RS13745	COG0191	fructose-bisphosphate aldolase activity
G7042_RS13750	COG0126	phosphoglycerate kinase activity
G7042_RS13755	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7042_RS13760	COG1940	carbohydrate kinase activity
G7042_RS13785	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G7042_RS13795	COG1136	(ABC) transporter
G7042_RS13845	COG5433	transposase activity
G7042_RS13850	COG0529	Catalyzes the synthesis of activated sulfate
G7042_RS13855	COG0471	metal ion transport
G7042_RS13855	COG3273	potassium ion transport
G7042_RS13860	COG2895	sulfate adenylyltransferase (ATP) activity
G7042_RS13865	COG0175	sulfate reduction
G7042_RS13870	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7042_RS13870	COG1648	precorrin-2 dehydrogenase activity
G7042_RS13875	COG0330	HflC and HflK could
G7042_RS13880	COG1585	Membrane protein implicated in regulation of membrane protease activity
G7042_RS13885	COG0517	IMP dehydrogenase activity
G7042_RS13885	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G7042_RS13890	COG0488	(ABC) transporter
G7042_RS13900	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G7042_RS13930	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G7042_RS13945	COG0668	transmembrane transport
G7042_RS13955	COG2731	YhcH YjgK YiaL family protein
G7042_RS13965	COG1794	racemase activity, acting on amino acids and derivatives
G7042_RS13980	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7042_RS14005	COG0733	neurotransmitter:sodium symporter activity
G7042_RS14015	COG0733	neurotransmitter:sodium symporter activity
G7042_RS14030	COG0561	phosphatase activity
G7042_RS14065	COG1846	Transcriptional regulator
G7042_RS14070	COG1764	response to oxidative stress
G7042_RS14075	COG2130	NADP-dependent
G7042_RS14095	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G7042_RS14100	COG1349	DNA-binding transcription factor activity
G7042_RS14140	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS14150	COG2982	Protein involved in outer membrane biogenesis
G7042_RS14155	COG1505	serine-type exopeptidase activity
G7042_RS14170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_RS14175	COG0745	RESPONSE REGULATOR receiver
G7042_RS14180	COG2205	protein histidine kinase activity
G7042_RS14185	COG2816	NAD+ diphosphatase activity
G7042_RS14215	COG0316	Belongs to the HesB IscA family
G7042_RS14225	COG0038	chloride channel
G7042_RS14230	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G7042_RS14245	COG0671	phosphoesterase, PA-phosphatase related
G7042_RS14255	COG0784	Response regulator, receiver
G7042_RS14255	COG3437	response regulator, receiver
G7042_RS14260	COG0583	DNA-binding transcription factor activity
G7042_RS14265	COG2076	Multidrug Resistance protein
G7042_RS14275	COG0346	lactoylglutathione lyase activity
G7042_RS14280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G7042_RS14285	COG1643	Atp-dependent helicase
G7042_RS14295	COG1489	DNA binding
G7042_RS14300	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G7042_RS14305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7042_RS14310	COG0617	tRNA 3'-terminal CCA addition
G7042_RS14315	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G7042_RS14320	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G7042_RS14325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G7042_RS14335	COG0842	Transport permease protein
G7042_RS14340	COG1131	(ABC) transporter
G7042_RS14355	COG0163	prenyltransferase activity
G7042_RS14360	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7042_RS14365	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G7042_RS14370	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G7042_RS14380	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G7042_RS14380	COG0506	proline dehydrogenase activity
G7042_RS14380	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G7042_RS14385	COG4991	sh3 domain protein
G7042_RS14390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G7042_RS14410	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G7042_RS14415	COG1640	4-alpha-glucanotransferase
G7042_RS14420	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G7042_RS14425	COG0676	glucose-6-phosphate 1-epimerase activity
G7042_RS14430	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G7042_RS14435	COG0840	transmembrane signaling receptor activity
G7042_RS14500	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G7042_RS14505	COG2885	chlorophyll binding
G7042_RS14510	COG0823	Involved in the tonB-independent uptake of proteins
G7042_RS14525	COG0811	peptide transport
G7042_RS14530	COG0824	Thioesterase
G7042_RS14535	COG3790	cyd operon protein YbgE
G7042_RS14540	COG4890	Cyd operon protein YbgT
G7042_RS14545	COG1294	oxidase, subunit
G7042_RS14550	COG1271	oxidase subunit
G7042_RS14555	COG2255	four-way junction helicase activity
G7042_RS14560	COG0632	four-way junction helicase activity
G7042_RS14570	COG0442	prolyl-tRNA aminoacylation
G7042_RS14580	COG1902	pentaerythritol trinitrate reductase activity
G7042_RS14590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G7042_RS14620	COG0714	Associated with various cellular activities
G7042_RS14630	COG0456	acetyltransferase
G7042_RS14640	COG1022	Amp-dependent synthetase and ligase
G7042_RS14650	COG2918	glutathione biosynthetic process
G7042_RS14655	COG0612	Peptidase, M16
G7042_RS14660	COG1238	metal cluster binding
G7042_RS14665	COG1064	alcohol dehydrogenase
G7042_RS14695	COG0359	binds to the 23S rRNA
G7042_RS14700	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G7042_RS14705	COG0360	Binds together with S18 to 16S ribosomal RNA
G7042_RS14710	COG1914	H( )-stimulated, divalent metal cation uptake system
G7042_RS14715	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7042_RS14740	COG2153	protein acetylation
G7042_RS14750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7042_RS14755	COG0557	exoribonuclease II activity
G7042_RS14760	COG3706	GGDEF domain
G7042_RS14765	COG1854	S-ribosylhomocysteine lyase activity
G7042_RS14780	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7042_RS14780	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G7042_RS14820	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G7042_RS14825	COG1047	Peptidyl-prolyl cis-trans
G7042_RS14830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G7042_RS14835	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G7042_RS14840	COG0196	riboflavin kinase activity
G7042_RS14845	COG0728	peptidoglycan biosynthetic process
G7042_RS14850	COG0268	Binds directly to 16S ribosomal RNA
G7042_RS14855	COG0640	Transcriptional regulator
G7042_RS14860	COG0583	DNA-binding transcription factor activity
G7042_RS14870	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G7042_RS14875	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G7042_RS14880	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G7042_RS14890	COG1051	belongs to the nudix hydrolase family
G7042_RS14895	COG3066	DNA modification
G7042_RS14905	COG0335	large ribosomal subunit rRNA binding
G7042_RS14910	COG0336	Belongs to the RNA methyltransferase TrmD family
G7042_RS14915	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G7042_RS14920	COG0228	four-way junction DNA binding
G7042_RS14925	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G7042_RS14930	COG4137	Cytochrome C assembly protein
G7042_RS14935	COG4536	flavin adenine dinucleotide binding
G7042_RS14940	COG1959	2 iron, 2 sulfur cluster binding
G7042_RS14945	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G7042_RS14945	COG1017	nitric oxide dioxygenase activity
G7042_RS14950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G7042_RS14955	COG0039	L-malate dehydrogenase activity
G7042_RS14960	COG4160	amino acid transport
G7042_RS14965	COG4215	(ABC) transporter
G7042_RS14970	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS14975	COG1126	abc transporter atp-binding protein
G7042_RS14980	COG1438	arginine binding
G7042_RS14985	COG2837	iron assimilation
G7042_RS14990	COG3842	ATPase activity
G7042_RS15000	COG1840	ABC-type Fe3 transport system, periplasmic component
G7042_RS15005	COG0347	Belongs to the P(II) protein family
G7042_RS15020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G7042_RS15040	COG1929	Belongs to the glycerate kinase type-1 family
G7042_RS15045	COG2610	gluconate transmembrane transporter activity
G7042_RS15050	COG3835	regulator
G7042_RS15055	COG3112	Uncharacterised protein family (UPF0231)
G7042_RS15070	COG0840	transmembrane signaling receptor activity
G7042_RS15075	COG3568	Endonuclease Exonuclease Phosphatase
G7042_RS15090	COG0513	Belongs to the DEAD box helicase family
G7042_RS15130	COG1448	Aminotransferase
G7042_RS15150	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G7042_RS15155	COG1328	CTP reductase activity
G7042_RS15190	COG1215	transferase activity, transferring glycosyl groups
G7042_RS15195	COG1649	PFAM Uncharacterised BCR, COG1649
G7042_RS15195	COG0726	polysaccharide deacetylase
G7042_RS15230	COG0840	transmembrane signaling receptor activity
G7042_RS15235	COG3397	chitin binding
G7042_RS15240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS15245	COG1126	abc transporter atp-binding protein
G7042_RS15255	COG0765	amino acid transport
G7042_RS15260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G7042_RS15265	COG0583	DNA-binding transcription factor activity
G7042_RS15270	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G7042_RS15275	COG4208	sulfate ABC transporter
G7042_RS15285	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G7042_RS15295	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G7042_RS15300	COG3174	membrane
G7042_RS15305	COG0110	maltose O-acetyltransferase activity
G7042_RS15335	COG1942	4-Oxalocrotonate Tautomerase
G7042_RS15345	COG0583	DNA-binding transcription factor activity
G7042_RS15350	COG0165	Argininosuccinate lyase
G7042_RS15355	COG0137	argininosuccinate synthase activity
G7042_RS15365	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G7042_RS15370	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G7042_RS15380	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G7042_RS15390	COG2072	flavoprotein involved in K transport
G7042_RS15395	COG1393	Belongs to the ArsC family
G7042_RS15400	COG0798	PFAM Bile acid sodium symporter
G7042_RS15420	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G7042_RS15440	COG3068	Protein conserved in bacteria
G7042_RS15450	COG0739	heme binding
G7042_RS15470	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G7042_RS15475	COG1121	(ABC) transporter
G7042_RS15480	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G7042_RS15485	COG0583	DNA-binding transcription factor activity
G7042_RS15495	COG1573	uracil-dna glycosylase
G7042_RS15510	COG2827	Endonuclease containing a URI domain
G7042_RS15530	COG0204	Acyl-transferase
G7042_RS15550	COG3118	belongs to the thioredoxin family
G7042_RS15555	COG2259	Doxx family
G7042_RS15630	COG1051	belongs to the nudix hydrolase family
G7042_RS15635	COG3150	esterase
G7042_RS15645	COG3151	Protein conserved in bacteria
G7042_RS15650	COG0494	nUDIX hydrolase
G7042_RS15655	COG1538	Outer membrane efflux protein
G7042_RS15660	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G7042_RS15660	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G7042_RS15665	COG1560	Kdo2-lipid A biosynthetic process
G7042_RS15680	COG1392	Phosphate transport regulator
G7042_RS15685	COG0306	phosphate transporter
G7042_RS15690	COG0617	tRNA 3'-terminal CCA addition
G7042_RS15695	COG3267	Type II secretory pathway component ExeA
G7042_RS15695	COG3409	Peptidoglycan-binding domain 1 protein
G7042_RS15705	COG1194	a g-specific adenine glycosylase
G7042_RS15710	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G7042_RS15720	COG3111	PFAM Bacterial OB fold (BOF) protein
G7042_RS15725	COG3240	lipase activity
G7042_RS15740	COG3009	Protein conserved in bacteria
G7042_RS15745	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G7042_RS15745	COG3008	intermembrane lipid transfer
G7042_RS15750	COG2995	paraquat-inducible protein a
G7042_RS15760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G7042_RS15775	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G7042_RS15780	COG2813	Specifically methylates the guanine in position
G7042_RS15785	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G7042_RS15790	COG0297	glycogen (starch) synthase activity
G7042_RS15825	COG1757	Na H antiporter
G7042_RS15835	COG0110	maltose O-acetyltransferase activity
G7042_RS15840	COG0366	Alpha amylase catalytic
G7042_RS15845	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G7042_RS15845	COG1263	PTS System
G7042_RS15860	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_RS15865	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_RS15870	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_RS15870	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G7042_RS15875	COG2723	6-phospho-beta-galactosidase activity
G7042_RS15880	COG1447	Phosphotransferase system cellobiose-specific component IIA
G7042_RS15885	COG1940	carbohydrate kinase activity
G7042_RS15895	COG1609	Transcriptional regulator
G7042_RS15905	COG0252	asparaginase activity
G7042_RS15920	COG1803	Methylglyoxal synthase
G7042_RS15945	COG1444	tRNA N-acetyltransferase activity
G7042_RS15950	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS15955	COG0835	chemotaxis
G7042_RS15955	COG0784	Response regulator, receiver
G7042_RS15965	COG3314	Sporulation integral membrane protein YlbJ
G7042_RS16090	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G7042_RS16095	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G7042_RS16115	COG0523	cobalamin synthesis protein
G7042_RS16125	COG1280	lysine exporter protein (LysE YggA)
G7042_RS16135	COG0583	DNA-binding transcription factor activity
G7042_RS16140	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS16145	COG2200	EAL domain
G7042_RS16150	COG1049	propionate catabolic process, 2-methylcitrate cycle
G7042_RS16160	COG0840	transmembrane signaling receptor activity
G7042_RS16165	COG0840	transmembrane signaling receptor activity
G7042_RS16175	COG5002	protein histidine kinase activity
G7042_RS16175	COG5001	Diguanylate cyclase
G7042_RS16175	COG3447	MASE1 domain protein
G7042_RS16180	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7042_RS16185	COG0508	dehydrogenase complex catalyzes the overall conversion of
G7042_RS16190	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G7042_RS16195	COG2186	Transcriptional regulator
G7042_RS16235	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7042_RS16245	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G7042_RS16255	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G7042_RS16260	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G7042_RS16265	COG0494	nUDIX hydrolase
G7042_RS16275	COG0653	protein targeting
G7042_RS16285	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G7042_RS16290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G7042_RS16295	COG0849	cell division
G7042_RS16300	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G7042_RS16305	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G7042_RS16310	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G7042_RS16315	COG0772	Belongs to the SEDS family
G7042_RS16320	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G7042_RS16325	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G7042_RS16330	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G7042_RS16340	COG0768	penicillin binding
G7042_RS16345	COG3116	cell division
G7042_RS16350	COG0275	rRNA processing
G7042_RS16355	COG2001	Belongs to the MraZ family
G7042_RS16365	COG0741	lytic transglycosylase activity
G7042_RS16365	COG1388	LysM domain
G7042_RS16370	COG1360	Flagellar Motor Protein
G7042_RS16375	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G7042_RS16380	COG1191	sigma factor activity
G7042_RS16405	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G7042_RS16410	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G7042_RS16440	COG1256	bacterial-type flagellum assembly
G7042_RS16440	COG4786	Flagellar basal body rod
G7042_RS16450	COG1706	bacterial-type flagellum-dependent cell motility
G7042_RS16455	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G7042_RS16460	COG4786	Flagellar basal body rod
G7042_RS16465	COG4786	Flagellar basal body rod
G7042_RS16470	COG1749	Flagellar hook protein flgE
G7042_RS16485	COG1815	bacterial-type flagellum-dependent cell motility
G7042_RS16495	COG2747	anti-sigma28 factor FlgM
G7042_RS16520	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G7042_RS16530	COG1677	Flagellar hook-basal body complex protein FliE
G7042_RS16560	COG2197	response regulator
G7042_RS16565	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G7042_RS16570	COG2199	diguanylate cyclase activity
G7042_RS16575	COG1278	Cold shock
G7042_RS16585	COG3706	GGDEF domain
G7042_RS16610	COG0347	Belongs to the P(II) protein family
G7042_RS16630	COG5433	transposase activity
G7042_RS16640	COG0346	lactoylglutathione lyase activity
G7042_RS16660	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G7042_RS16665	COG1074	ATP-dependent DNA helicase activity
G7042_RS16670	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G7042_RS16675	COG2259	Doxx family
G7042_RS16680	COG1741	Belongs to the pirin family
G7042_RS16690	COG0583	DNA-binding transcription factor activity
G7042_RS16715	COG1176	ABC-type spermidine putrescine transport system, permease component I
G7042_RS16725	COG3842	ATPase activity
G7042_RS16735	COG2203	Gaf domain
G7042_RS16735	COG2199	diguanylate cyclase activity
G7042_RS16755	COG1247	-acetyltransferase
G7042_RS16760	COG0753	catalase activity
G7042_RS16785	COG0494	nUDIX hydrolase
G7042_RS16790	COG0628	permease
G7042_RS16795	COG3284	Transcriptional regulator
G7042_RS16805	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G7042_RS16805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS16805	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
G7042_RS16810	COG1461	Dihydroxyacetone kinase
G7042_RS16815	COG2376	Dihydroxyacetone kinase
G7042_RS16820	COG2252	PERMEase
G7042_RS16870	COG0203	ribosomal protein L17
G7042_RS16875	COG0202	RNA polymerase activity
G7042_RS16880	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G7042_RS16885	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G7042_RS16890	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G7042_RS16895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G7042_RS16900	COG0201	protein transport
G7042_RS16905	COG0200	Binds to the 23S rRNA
G7042_RS16910	COG1841	ribosomal large subunit assembly
G7042_RS16915	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G7042_RS16920	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G7042_RS16925	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G7042_RS16930	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G7042_RS16935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G7042_RS16940	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G7042_RS16945	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G7042_RS16950	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G7042_RS16955	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G7042_RS16960	COG0255	Belongs to the universal ribosomal protein uL29 family
G7042_RS16965	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G7042_RS16970	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G7042_RS16975	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G7042_RS16980	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G7042_RS16985	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G7042_RS16990	COG0089	rRNA binding
G7042_RS16995	COG0088	Forms part of the polypeptide exit tunnel
G7042_RS17000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G7042_RS17005	COG0051	transcription antitermination factor activity, RNA binding
G7042_RS17025	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G7042_RS17030	COG2183	response to ionizing radiation
G7042_RS17050	COG0596	Alpha beta hydrolase
G7042_RS17055	COG1040	competence protein
G7042_RS17060	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G7042_RS17060	COG0316	Belongs to the HesB IscA family
G7042_RS17065	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G7042_RS17070	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G7042_RS17075	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7042_RS17080	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G7042_RS17085	COG4942	peptidase
G7042_RS17095	COG1609	Transcriptional regulator
G7042_RS17100	COG0800	Aldolase
G7042_RS17105	COG0129	dihydroxy-acid dehydratase activity
G7042_RS17110	COG3265	gluconokinase activity
G7042_RS17115	COG2610	gluconate transmembrane transporter activity
G7042_RS17120	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7042_RS17125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G7042_RS17135	COG0456	acetyltransferase
G7042_RS17145	COG1490	D-aminoacyl-tRNA deacylase activity
G7042_RS17150	COG1295	ribonuclease BN
G7042_RS17155	COG1217	gtp-binding protein TYPA
G7042_RS17160	COG0174	glutamine synthetase
G7042_RS17170	COG3852	Histidine kinase
G7042_RS17175	COG2204	response regulator
G7042_RS17180	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G7042_RS17185	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G7042_RS17195	COG3078	GTPase activator activity
G7042_RS17205	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G7042_RS17215	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G7042_RS17220	COG0408	coproporphyrinogen oxidase activity
G7042_RS17225	COG0009	L-threonylcarbamoyladenylate synthase
G7042_RS17235	COG0551	DNA topoisomerase type I activity
G7042_RS17240	COG2922	Belongs to the Smg family
G7042_RS17245	COG0758	DNA mediated transformation
G7042_RS17250	COG1652	LysM domain
G7042_RS17255	COG0242	peptide deformylase activity
G7042_RS17260	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G7042_RS17265	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G7042_RS17265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G7042_RS17270	COG0569	domain protein
G7042_RS17275	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7042_RS17300	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G7042_RS17305	COG0686	Belongs to the AlaDH PNT family
G7042_RS17310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G7042_RS17310	COG0519	Catalyzes the synthesis of GMP from XMP
G7042_RS17320	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G7042_RS17330	COG1012	belongs to the aldehyde dehydrogenase family
G7042_RS17340	COG2962	Rard protein
G7042_RS17350	COG1280	lysine exporter protein (LysE YggA)
G7042_RS17375	COG2116	formate transmembrane transporter activity
G7042_RS17380	COG1648	precorrin-2 dehydrogenase activity
G7042_RS17380	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G7042_RS17385	COG2239	Acts as a magnesium transporter
G7042_RS17395	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G7042_RS17400	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G7042_RS17410	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G7042_RS17420	COG0514	ATP-dependent DNA helicase (RecQ)
G7042_RS17425	COG2050	protein possibly involved in aromatic compounds catabolism
G7042_RS17440	COG2258	MOSC domain
G7042_RS17445	COG1177	transmembrane transport
G7042_RS17450	COG1176	ABC-type spermidine putrescine transport system, permease component I
G7042_RS17455	COG3842	ATPase activity
G7042_RS17475	COG0174	glutamine synthetase
G7042_RS17495	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G7042_RS17500	COG0443	Heat shock 70 kDa protein
G7042_RS17515	COG0366	Alpha amylase catalytic
G7042_RS17520	COG1086	Polysaccharide biosynthesis protein
G7042_RS17525	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G7042_RS17550	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_RS17570	COG1083	cytidylyl-transferase
G7042_RS17580	COG2089	acid synthase
G7042_RS17615	COG5433	transposase activity
G7042_RS17625	COG4310	Domain of unknown function (DUF2172)
G7042_RS17660	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7042_RS17665	COG0745	RESPONSE REGULATOR receiver
G7042_RS17670	COG2205	protein histidine kinase activity
G7042_RS17680	COG0281	malic enzyme
G7042_RS17685	COG0702	epimerase
G7042_RS17690	COG0254	rRNA binding
G7042_RS17695	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G7042_RS17705	COG1309	transcriptional regulator
G7042_RS17725	COG0129	dihydroxy-acid dehydratase activity
G7042_RS17735	COG3978	acetolactate synthase activity
G7042_RS17745	COG0606	chelatase, subunit chli
G7042_RS17755	COG1683	Conserved Protein
G7042_RS17765	COG1335	isochorismatase
G7042_RS17775	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G7042_RS17780	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G7042_RS17785	COG3639	organic phosphonate transmembrane transporter activity
G7042_RS17790	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G7042_RS17795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G7042_RS17805	COG3084	Protein conserved in bacteria
G7042_RS17810	COG5001	Diguanylate cyclase
G7042_RS17810	COG2203	Gaf domain
G7042_RS17810	COG4251	negative regulation of phosphorylation
G7042_RS17810	COG3706	GGDEF domain
G7042_RS17825	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G7042_RS17835	COG1561	YicC-like family, N-terminal region
G7042_RS17870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G7042_RS17885	COG1063	alcohol dehydrogenase
G7042_RS17900	COG0210	DNA helicase
G7042_RS17905	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G7042_RS17910	COG2166	iron-sulfur cluster assembly
G7042_RS17915	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G7042_RS17945	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
G7042_RS17950	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7042_RS17955	COG1739	Uncharacterized protein family UPF0029
G7042_RS17960	COG0006	proline dipeptidase activity
G7042_RS17965	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G7042_RS17970	COG1024	Enoyl-CoA hydratase
G7042_RS17970	COG1250	3-hydroxyacyl-CoA dehydrogenase
G7042_RS17975	COG0183	Belongs to the thiolase family
G7042_RS18000	COG0425	Belongs to the sulfur carrier protein TusA family
G7042_RS18005	COG0251	oxidation-reduction process
G7042_RS18010	COG2885	chlorophyll binding
G7042_RS18020	COG0752	glycyl-tRNA synthetase alpha subunit
G7042_RS18025	COG0751	glycine-tRNA ligase activity
G7042_RS18045	COG2188	Transcriptional regulator
G7042_RS18050	COG3604	Transcriptional regulator
G7042_RS18060	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_RS18070	COG0348	domain, Protein
G7042_RS18075	COG0814	amino acid
G7042_RS18090	COG2200	EAL domain
G7042_RS18090	COG2202	Pas domain
G7042_RS18090	COG2199	diguanylate cyclase activity
G7042_RS18125	COG3328	transposase activity
G7042_RS18165	COG1609	Transcriptional regulator
G7042_RS18205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G7042_RS18230	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G7042_RS18245	COG3118	belongs to the thioredoxin family
G7042_RS18250	COG0513	Belongs to the DEAD box helicase family
G7042_RS18255	COG0248	Ppx GppA phosphatase
G7042_RS18265	COG0742	ribosomal rna small subunit methyltransferase
G7042_RS18270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS18290	COG0084	hydrolase, TatD family'
G7042_RS18295	COG0805	protein transport
G7042_RS18300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7042_RS18310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G7042_RS18315	COG3165	ubiquinone biosynthetic process from chorismate
G7042_RS18325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G7042_RS18330	COG0402	S-adenosylhomocysteine deaminase activity
G7042_RS18370	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G7042_RS18375	COG0848	biopolymer transport protein
G7042_RS18380	COG0811	peptide transport
G7042_RS18385	COG0811	peptide transport
G7042_RS18395	COG2771	luxR family
G7042_RS18400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G7042_RS18405	COG1349	DNA-binding transcription factor activity
G7042_RS18410	COG0745	RESPONSE REGULATOR receiver
G7042_RS18415	COG2205	protein histidine kinase activity
G7042_RS18425	COG4452	Inner membrane protein CreD
G7042_RS18430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G7042_RS18435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G7042_RS18440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G7042_RS18445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G7042_RS18450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G7042_RS18455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G7042_RS18460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G7042_RS18470	COG0356	it plays a direct role in the translocation of protons across the membrane
G7042_RS18475	COG3312	ion transport
G7042_RS18480	COG1475	DNA binding
G7042_RS18485	COG1192	Involved in chromosome partitioning
G7042_RS18490	COG0357	Ribosomal RNA small subunit methyltransferase G
G7042_RS18495	COG0445	tRNA wobble uridine modification
G7042_RS18500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G7042_RS18505	COG4774	siderophore transport
G7042_RS18510	COG4615	Cyclic peptide transporter
G7042_RS18515	COG1120	ATPase activity
G7042_RS18520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G7042_RS18530	COG4774	siderophore transport
G7042_RS18535	COG4607	ABC-type enterochelin transport system periplasmic component
G7042_RS18540	COG4604	ABC transporter, ATP-binding protein
G7042_RS18545	COG4605	iron ion homeostasis
G7042_RS18550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G7042_RS18555	COG1132	(ABC) transporter
G7042_RS18560	COG2375	cellular response to nickel ion
G7042_RS18560	COG1132	(ABC) transporter
G7042_RS18570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_RS18580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G7042_RS18595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G7042_RS18600	COG0706	membrane insertase activity
G7042_RS18605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G7042_RS18610	COG0594	ribonuclease P activity
G7042_RS18615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G7042_RS18620	COG1126	abc transporter atp-binding protein
G7042_RS18635	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G7042_RS18640	COG0592	DNA-directed DNA polymerase activity
G7042_RS18665	COG2378	regulation of single-species biofilm formation
G7042_RS18670	COG0071	Belongs to the small heat shock protein (HSP20) family
G7042_RS18675	COG0071	Belongs to the small heat shock protein (HSP20) family
G7042_RS18690	COG3977	Valine--pyruvate aminotransferase
G7042_RS18705	COG2814	Major facilitator Superfamily
G7042_RS18715	COG0745	RESPONSE REGULATOR receiver
G7042_RS18720	COG2205	protein histidine kinase activity
G7042_RS18740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G7042_RS18745	COG4191	Histidine kinase
G7042_RS18745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS18750	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G7042_RS18755	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_RS18760	COG1309	transcriptional regulator
G7042_RS18790	COG0561	phosphatase activity
G7042_RS18795	COG2267	carboxylic ester hydrolase activity
G7042_RS18800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G7042_RS18805	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G7042_RS18810	COG1758	RNA polymerase activity
G7042_RS18815	COG0194	GDP metabolic process
G7042_RS18820	COG0859	PFAM glycosyl transferase family 9
G7042_RS18825	COG3642	lipopolysaccharide core region biosynthetic process
G7042_RS18865	COG0589	response to stress
G7042_RS18870	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G7042_RS18880	COG1528	Iron-storage protein
G7042_RS18885	COG2081	HI0933 family
G7042_RS18935	COG5433	transposase activity
G7042_RS18940	COG2205	protein histidine kinase activity
G7042_RS18940	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS18950	COG2205	protein histidine kinase activity
G7042_RS18950	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G7042_RS18960	COG3275	phosphorelay sensor kinase activity
G7042_RS18965	COG3279	Response regulator of the LytR AlgR family
G7042_RS18970	COG2223	nitrite transmembrane transporter activity
G7042_RS18975	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G7042_RS18980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G7042_RS18995	COG0583	DNA-binding transcription factor activity
G7042_RS19000	COG4206	TonB-dependent receptor
G7042_RS19005	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G7042_RS19050	COG0583	DNA-binding transcription factor activity
G7042_RS19055	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G7042_RS19060	COG0166	Belongs to the GPI family
G7042_RS19070	COG0668	transmembrane transport
G7042_RS19075	COG1309	transcriptional regulator
G7042_RS19080	COG0756	dUTP diphosphatase activity
G7042_RS19085	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G7042_RS19090	COG2003	Belongs to the UPF0758 family
G7042_RS19095	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G7042_RS19100	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G7042_RS19110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G7042_RS19115	COG2990	Protein conserved in bacteria
G7042_RS19120	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G7042_RS19125	COG0859	PFAM glycosyl transferase family 9
G7042_RS19130	COG0463	Glycosyl transferase, family 2
G7042_RS19135	COG0859	PFAM glycosyl transferase family 9
G7042_RS19140	COG1519	Transferase
G7042_RS19155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS19160	COG1609	Transcriptional regulator
G7042_RS19190	COG1580	Controls the rotational direction of flagella during chemotaxis
G7042_RS19195	COG3161	chorismate lyase activity
G7042_RS19200	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G7042_RS19205	COG2937	Belongs to the GPAT DAPAT family
G7042_RS19210	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G7042_RS19225	COG0534	Mate efflux family protein
G7042_RS19230	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G7042_RS19235	COG2205	protein histidine kinase activity
G7042_RS19240	COG0745	RESPONSE REGULATOR receiver
G7042_RS19250	COG1045	serine acetyltransferase
G7042_RS19260	COG3074	FtsZ-dependent cytokinesis
G7042_RS19265	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G7042_RS19275	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G7042_RS19325	COG1609	Transcriptional regulator
G7042_RS19330	COG0385	Bile acid
G7042_RS19335	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G7042_RS19355	COG0583	DNA-binding transcription factor activity
G7042_RS19360	COG1079	Belongs to the binding-protein-dependent transport system permease family
G7042_RS19365	COG4603	Belongs to the binding-protein-dependent transport system permease family
G7042_RS19370	COG3845	ABC transporter
G7042_RS19375	COG1744	ABC transporter substrate-binding protein PnrA-like
G7042_RS19380	COG0210	DNA helicase
G7042_RS19425	COG2391	methyltransferase activity
G7042_RS19430	COG5433	transposase activity
G7042_RS19440	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G7042_RS19455	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G7042_RS19460	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G7042_RS19470	COG0018	arginyl-trna synthetase
G7042_RS19480	COG1595	DNA-templated transcription, initiation
G7042_RS19490	COG1968	undecaprenyl-diphosphatase activity
G7042_RS19495	COG0667	Aldo Keto reductase
G7042_RS19500	COG2017	converts alpha-aldose to the beta-anomer
G7042_RS19505	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G7042_RS19515	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G7042_RS19520	COG1609	Transcriptional regulator
G7042_RS19525	COG3250	beta-galactosidase activity
G7042_RS19540	COG4211	Belongs to the binding-protein-dependent transport system permease family
G7042_RS19550	COG3328	transposase activity
G7042_RS19585	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G7042_RS19590	COG1288	antiporter activity
G7042_RS19595	COG1438	arginine binding
G7042_RS19600	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G7042_RS19605	COG0540	Belongs to the ATCase OTCase family
G7042_RS19625	COG0688	phosphatidylethanolamine metabolic process
G7042_RS19635	COG3040	lipid binding
G7042_RS19645	COG1979	alcohol dehydrogenase
G7042_RS19650	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G7042_RS19655	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G7042_RS19665	COG2964	Protein conserved in bacteria
G7042_RS19670	COG3681	Belongs to the UPF0597 family
G7042_RS19680	COG0446	pyridine nucleotide-disulphide oxidoreductase
G7042_RS19685	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G7042_RS19690	COG0564	pseudouridine synthase activity
G7042_RS19700	COG0542	response to heat
G7042_RS19705	COG2502	aspartate--ammonia ligase
G7042_RS19710	COG1522	sequence-specific DNA binding
G7042_RS19720	COG5413	integral membrane protein
G7042_RS19725	COG0517	IMP dehydrogenase activity
G7042_RS19725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G7042_RS19725	COG0617	tRNA 3'-terminal CCA addition
G7042_RS19730	COG1028	Short-chain dehydrogenase reductase Sdr
G7042_RS19745	COG2205	protein histidine kinase activity
G7042_RS19755	COG2204	response regulator
G7042_RS19765	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G7042_RS19770	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G7042_RS19800	COG0243	molybdopterin cofactor binding
G7042_RS19805	COG3005	denitrification pathway
G7042_RS19810	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7042_RS19815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G7042_RS19820	COG0569	domain protein
G7042_RS19825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G7042_RS19850	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7042_RS19865	COG0250	Participates in transcription elongation, termination and antitermination
G7042_RS19870	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G7042_RS19875	COG0081	regulation of translation
G7042_RS19880	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G7042_RS19885	COG0222	ribosome binding
G7042_RS19890	COG0085	RNA polymerase activity
G7042_RS19895	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G7042_RS19900	COG2964	Protein conserved in bacteria
G7042_RS19915	COG2923	Belongs to the DsrF TusC family
G7042_RS19920	COG2168	tRNA wobble position uridine thiolation
G7042_RS19925	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G7042_RS19930	COG0049	tRNA binding
G7042_RS19935	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G7042_RS19940	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G7042_RS19945	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G7042_RS20005	COG3047	cAMP biosynthetic process
G7042_RS20035	COG3135	benzoate transporter
G7042_RS20040	COG1396	sequence-specific DNA binding
G7042_RS20070	COG2926	Belongs to the UPF0265 family
G7042_RS20080	COG3028	Belongs to the UPF0307 family
G7042_RS20085	COG0312	modulator of DNA gyrase
G7042_RS20090	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G7042_RS20095	COG5007	Belongs to the BolA IbaG family
G7042_RS20105	COG2854	intermembrane phospholipid transfer
G7042_RS20110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G7042_RS20115	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G7042_RS20120	COG1127	ABC transporter
G7042_RS20125	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G7042_RS20125	COG0517	IMP dehydrogenase activity
G7042_RS20130	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G7042_RS20135	COG3117	lipopolysaccharide transmembrane transporter activity
G7042_RS20140	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G7042_RS20145	COG1137	ATPase activity
G7042_RS20150	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G7042_RS20160	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS20165	COG1660	Displays ATPase and GTPase activities
G7042_RS20170	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS20190	COG3964	amidohydrolase
G7042_RS20220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7042_RS20225	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G7042_RS20235	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G7042_RS20240	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G7042_RS20245	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G7042_RS20250	COG0723	plastoquinol--plastocyanin reductase activity
G7042_RS20255	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G7042_RS20260	COG2857	Cytochrome c1
G7042_RS20265	COG0625	glutathione transferase activity
G7042_RS20270	COG2969	positive regulation of protein catabolic process
G7042_RS20275	COG2823	Periplasmic or secreted lipoprotein
G7042_RS20280	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G7042_RS20290	COG3107	peptidoglycan biosynthetic process
G7042_RS20295	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G7042_RS20320	COG1987	bacterial-type flagellum assembly
G7042_RS20370	COG2249	NAD(P)H dehydrogenase (quinone) activity
G7042_RS20385	COG1770	oligopeptidase
G7042_RS20405	COG3714	YhhN family
G7042_RS20430	COG1301	dicarboxylic acid transport
G7042_RS20440	COG2095	MarC family integral membrane protein
G7042_RS20450	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G7042_RS20460	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G7042_RS20470	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G7042_RS20500	COG0742	ribosomal rna small subunit methyltransferase
G7042_RS20505	COG0552	protein localization to endoplasmic reticulum
G7042_RS20510	COG2884	Cell division ATP-binding protein ftsE
G7042_RS20515	COG2177	Part of the ABC transporter FtsEX involved in
G7042_RS20525	COG0288	reversible hydration of carbon dioxide
G7042_RS20530	COG2188	Transcriptional regulator
G7042_RS20535	COG1228	amidohydrolase
G7042_RS20540	COG0010	Belongs to the arginase family
G7042_RS20545	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G7042_RS20550	COG2986	histidine ammonia-lyase
G7042_RS20555	COG0387	Pfam Sodium calcium exchanger
G7042_RS20560	COG2264	protein methyltransferase activity
G7042_RS20565	COG2200	EAL domain
G7042_RS20565	COG2199	diguanylate cyclase activity
G7042_RS20625	COG1077	Cell shape determining protein MreB Mrl
G7042_RS20630	COG1792	Involved in formation and maintenance of cell shape
G7042_RS20635	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G7042_RS20640	COG0424	maF-like protein
G7042_RS20645	COG1530	ribonuclease E activity
G7042_RS20650	COG3164	Protein of unknown function
G7042_RS20660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G7042_RS20665	COG0312	modulator of DNA gyrase
G7042_RS20680	COG0477	Major facilitator Superfamily
G7042_RS20690	COG3437	response regulator, receiver
G7042_RS20695	COG5002	protein histidine kinase activity
G7042_RS20695	COG0784	Response regulator, receiver
G7042_RS20695	COG2205	protein histidine kinase activity
G7042_RS20700	COG2172	sigma factor antagonist activity
G7042_RS20705	COG1366	Belongs to the anti-sigma-factor antagonist family
G7042_RS20715	COG3700	Belongs to the class B bacterial acid phosphatase family
G7042_RS20725	COG1639	'signal transduction protein
G7042_RS20750	COG0189	ligase activity
G7042_RS20755	COG0642	Histidine kinase
G7042_RS20760	COG0745	RESPONSE REGULATOR receiver
G7042_RS20795	COG0004	ammonium transporteR
G7042_RS20800	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G7042_RS20810	COG2165	general secretion pathway protein
G7042_RS20815	COG0084	hydrolase, TatD family'
G7042_RS20830	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G7042_RS20835	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G7042_RS20840	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G7042_RS20845	COG0813	purine-nucleoside phosphorylase activity
G7042_RS20855	COG0560	Phosphoserine phosphatase
G7042_RS20880	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G7042_RS20890	COG0776	regulation of translation
G7042_RS20905	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G7042_RS20910	COG0735	belongs to the Fur family
G7042_RS20930	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G7042_RS20935	COG0513	Belongs to the DEAD box helicase family
G7042_RS20940	COG3022	response to hydroperoxide
G7042_RS20955	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G7042_RS20960	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G7042_RS20965	COG0762	integral membrane protein
G7042_RS20970	COG1872	DUF167
G7042_RS20985	COG4166	transmembrane transport
G7042_RS20995	COG0110	maltose O-acetyltransferase activity
G7042_RS21005	COG1024	Enoyl-CoA hydratase
G7042_RS21020	COG4221	oxidoreductase activity
G7042_RS21030	COG2957	Belongs to the agmatine deiminase family
G7042_RS21045	COG3328	transposase activity
G7042_RS21140	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G7042_RS21145	COG0352	thiamine-phosphate diphosphorylase activity
G7042_RS21150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G7042_RS21160	COG2022	thiamine diphosphate biosynthetic process
G7042_RS21190	COG5433	transposase activity
G7042_RS21195	COG0814	amino acid
G7042_RS21200	COG3932	Exopolysaccharide synthesis, ExoD
G7042_RS21250	COG1494	fructose-1,6-bisphosphatase
G7042_RS21265	COG2959	enzyme of heme biosynthesis
G7042_RS21275	COG0181	hydroxymethylbilane synthase activity
G7042_RS21280	COG3072	Adenylate cyclase
G7042_RS21285	COG0400	carboxylic ester hydrolase activity
G7042_RS21290	COG1965	Belongs to the frataxin family
G7042_RS21300	COG0019	diaminopimelate decarboxylase activity
G7042_RS21305	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G7042_RS21320	COG1011	Hydrolase
G7042_RS21330	COG0668	transmembrane transport
G7042_RS21340	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G7042_RS21345	COG0561	phosphatase activity
G7042_RS21370	COG0842	Transport permease protein
G7042_RS21370	COG1129	ABC transporter
G7042_RS21380	COG1058	Belongs to the CinA family
G7042_RS21380	COG1546	Belongs to the CinA family
G7042_RS21385	COG1418	mRNA catabolic process
G7042_RS21390	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G7042_RS21400	COG1522	sequence-specific DNA binding
G7042_RS21405	COG1368	sulfuric ester hydrolase activity
G7042_RS21425	COG1285	pathogenesis
G7042_RS21445	COG4221	oxidoreductase activity
G7042_RS21465	COG1979	alcohol dehydrogenase
G7042_RS21475	COG2873	o-acetylhomoserine
G7042_RS21490	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G7042_RS21505	COG5380	lipid catabolic process
G7042_RS21510	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G7042_RS21520	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G7042_RS21525	COG2949	membrane
G7042_RS21540	COG5433	transposase activity
G7042_RS21575	COG5433	transposase activity
G7042_RS21625	COG0582	viral genome integration into host DNA
G7042_RS21640	COG0795	lipopolysaccharide-transporting ATPase activity
G7042_RS21645	COG0795	lipopolysaccharide-transporting ATPase activity
G7042_RS21650	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G7042_RS21655	COG2927	DNA polymerase III (CHI subunit)
G7042_RS21670	COG0586	Pfam SNARE associated Golgi protein
G7042_RS21675	COG1686	Belongs to the peptidase S11 family
G7042_RS21700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G7042_RS21705	COG0527	aspartate kinase activity
G7042_RS21710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G7042_RS21720	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G7042_RS21725	COG1546	Belongs to the CinA family
G7042_RS21730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G7042_RS21770	COG1346	cytolysis
G7042_RS21785	COG0527	aspartate kinase activity
G7042_RS21785	COG0460	homoserine dehydrogenase
G7042_RS21790	COG0626	cystathionine gamma-synthase activity
G7042_RS21805	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G7042_RS21810	COG0814	amino acid
G7042_RS21815	COG1218	3'(2'),5'-bisphosphate nucleotidase
G7042_RS21820	COG0494	nUDIX hydrolase
G7042_RS21825	COG1011	Hydrolase
G7042_RS21830	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G7042_RS21845	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G7042_RS21855	COG3156	type II secretion system protein K
G7042_RS21860	COG4795	General secretion pathway protein
G7042_RS21865	COG2165	general secretion pathway protein
G7042_RS21875	COG2165	general secretion pathway protein
G7042_RS21880	COG1459	type II secretion system
G7042_RS21885	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G7042_RS21905	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G7042_RS21910	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G7042_RS21930	COG0456	acetyltransferase
G7042_RS21935	COG3133	Outer membrane lipoprotein
G7042_RS21950	COG2771	luxR family
G7042_RS21965	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
G7042_RS21980	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G7042_RS21980	COG2213	PTS system mannitol-specific
G7042_RS21985	COG0246	Mannitol dehydrogenase
G7042_RS21990	COG3722	fumarate hydratase activity
G7042_RS21995	COG3263	regulation of cellular component size
G7042_RS22000	COG0484	heat shock protein binding
G7042_RS22020	COG1671	Belongs to the UPF0178 family
G7042_RS22035	COG1988	membrane-bound metal-dependent
G7042_RS22040	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G7042_RS22050	COG0513	Belongs to the DEAD box helicase family
G7042_RS22075	COG1575	Belongs to the MenA family. Type 1 subfamily
G7042_RS22080	COG1169	isochorismate synthase
G7042_RS22085	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G7042_RS22090	COG0596	Alpha beta hydrolase
G7042_RS22095	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G7042_RS22105	COG0318	PFAM AMP-dependent synthetase and ligase
G7042_RS22115	COG5433	transposase activity
G7042_RS22165	COG0513	Belongs to the DEAD box helicase family
G7042_RS22185	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
G7042_RS22245	COG1280	lysine exporter protein (LysE YggA)
G7042_RS22250	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G7042_RS22265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G7042_RS22295	COG0745	RESPONSE REGULATOR receiver
G7042_RS22300	COG3104	oligopeptide transport
G7042_RS22305	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G7042_RS22310	COG1555	photosystem II stabilization
G7042_RS22320	COG2350	Protein conserved in bacteria
G7042_RS22325	COG2917	probably involved in intracellular septation
G7042_RS22330	COG0076	glutamate decarboxylase activity
G7042_RS22335	COG1272	protein, Hemolysin III
G7042_RS22340	COG2985	domain, Protein
G7042_RS22340	COG0569	domain protein
G7042_RS22350	COG0835	chemotaxis
G7042_RS22350	COG0784	Response regulator, receiver
G7042_RS22355	COG2755	lipolytic protein G-D-S-L family
G7042_RS22360	COG4181	ATPase activity
G7042_RS22365	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G7042_RS22370	COG1090	epimerase
G7042_RS22375	COG2200	EAL domain
G7042_RS22380	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G7042_RS22385	COG4935	Belongs to the peptidase S8 family
G7042_RS22385	COG2234	aminopeptidase activity
G7042_RS22390	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G7042_RS22395	COG3171	Protein conserved in bacteria
G7042_RS22400	COG2066	Belongs to the glutaminase family
G7042_RS22405	COG2897	thiosulfate sulfurtransferase activity
G7042_RS22415	COG1132	(ABC) transporter
G7042_RS22430	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G7042_RS22460	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
G7042_RS22465	COG3300	MHYT domain
G7042_RS22465	COG5001	Diguanylate cyclase
G7042_RS22485	COG4628	conserved protein (DUF2132)
G7042_RS22490	COG0688	phosphatidylethanolamine metabolic process
G7042_RS22500	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G7042_RS22545	COG1278	Cold shock
G7042_RS22560	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G7042_RS22610	COG0848	biopolymer transport protein
G7042_RS22615	COG0811	peptide transport
G7042_RS22620	COG0811	peptide transport
G7042_RS22630	COG4206	TonB-dependent receptor
G7042_RS22635	COG5433	transposase activity
G7042_RS22655	COG4239	(ABC) transporter, permease
G7042_RS22660	COG0747	negative chemotaxis
G7042_RS22665	COG0444	Belongs to the ABC transporter superfamily
G7042_RS22670	COG4608	Belongs to the ABC transporter superfamily
G7042_RS22675	COG2195	Cleaves the N-terminal amino acid of tripeptides
G7042_RS22695	COG3646	Phage regulatory protein
G7042_RS22720	COG4790	Type iii secretion
G7042_RS22725	COG4794	Type iii secretion
G7042_RS22730	COG4791	protein targeting
G7042_RS22735	COG4792	protein secretion
G7042_RS22785	COG1484	DNA-dependent DNA replication
G7042_RS22880	COG2916	Histone family protein nucleoid-structuring protein H-NS
G7042_RS22885	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G7042_RS22890	COG2361	Protein of unknown function DUF86
G7042_RS22910	COG1192	Involved in chromosome partitioning
G7042_RS22955	COG1317	bacterial-type flagellum organization
G7042_RS23045	COG0457	Tetratricopeptide repeat
G7042_RS23135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G7042_RS23155	COG1192	Involved in chromosome partitioning
G7042_RS23205	COG2003	Belongs to the UPF0758 family
G7042_RS23395	COG2361	Protein of unknown function DUF86
G7042_RS23415	COG1192	Involved in chromosome partitioning
G7042_RS23540	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
G7042_RS23555	COG3736	Type IV secretory pathway, component VirB8
G7042_RS23575	COG3451	type IV secretory pathway VirB4
G7042_RS23590	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G7042_RS23690	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G7042_RS23700	COG3093	addiction module antidote protein HigA
G7042_RS23775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII