locus-tag	class	description
BHG40_RS00095	COG3646	Phage regulatory protein
BHG40_RS00120	COG2195	Cleaves the N-terminal amino acid of tripeptides
BHG40_RS00130	COG4608	Belongs to the ABC transporter superfamily
BHG40_RS00135	COG0444	Belongs to the ABC transporter superfamily
BHG40_RS00140	COG0747	negative chemotaxis
BHG40_RS00145	COG4239	(ABC) transporter, permease
BHG40_RS00170	COG4206	TonB-dependent receptor
BHG40_RS00180	COG0811	peptide transport
BHG40_RS00185	COG0811	peptide transport
BHG40_RS00190	COG0848	biopolymer transport protein
BHG40_RS00240	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHG40_RS00255	COG1278	Cold shock
BHG40_RS00300	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BHG40_RS00310	COG0688	phosphatidylethanolamine metabolic process
BHG40_RS00315	COG4628	conserved protein (DUF2132)
BHG40_RS00335	COG5001	Diguanylate cyclase
BHG40_RS00335	COG3300	MHYT domain
BHG40_RS00340	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
BHG40_RS00370	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
BHG40_RS00375	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_RS00395	COG1132	(ABC) transporter
BHG40_RS00405	COG2897	thiosulfate sulfurtransferase activity
BHG40_RS00410	COG2066	Belongs to the glutaminase family
BHG40_RS00415	COG3171	Protein conserved in bacteria
BHG40_RS00420	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BHG40_RS00425	COG2234	aminopeptidase activity
BHG40_RS00425	COG4935	Belongs to the peptidase S8 family
BHG40_RS00430	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHG40_RS00435	COG2200	EAL domain
BHG40_RS00440	COG1090	epimerase
BHG40_RS00445	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BHG40_RS00450	COG4181	ATPase activity
BHG40_RS00455	COG2755	lipolytic protein G-D-S-L family
BHG40_RS00460	COG0784	Response regulator, receiver
BHG40_RS00460	COG0835	chemotaxis
BHG40_RS00480	COG0076	glutamate decarboxylase activity
BHG40_RS00485	COG2917	probably involved in intracellular septation
BHG40_RS00490	COG2350	Protein conserved in bacteria
BHG40_RS00500	COG1555	photosystem II stabilization
BHG40_RS00505	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BHG40_RS00510	COG3104	oligopeptide transport
BHG40_RS00545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_RS00560	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
BHG40_RS00565	COG1280	lysine exporter protein (LysE YggA)
BHG40_RS00625	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
BHG40_RS00645	COG0513	Belongs to the DEAD box helicase family
BHG40_RS00700	COG5433	transposase activity
BHG40_RS00755	COG0582	viral genome integration into host DNA
BHG40_RS00770	COG0795	lipopolysaccharide-transporting ATPase activity
BHG40_RS00775	COG0795	lipopolysaccharide-transporting ATPase activity
BHG40_RS00785	COG2927	DNA polymerase III (CHI subunit)
BHG40_RS00800	COG0586	Pfam SNARE associated Golgi protein
BHG40_RS00805	COG1686	Belongs to the peptidase S11 family
BHG40_RS00830	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BHG40_RS00835	COG0527	aspartate kinase activity
BHG40_RS00840	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BHG40_RS00850	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BHG40_RS00855	COG1546	Belongs to the CinA family
BHG40_RS00860	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BHG40_RS00900	COG1346	cytolysis
BHG40_RS00915	COG0460	homoserine dehydrogenase
BHG40_RS00915	COG0527	aspartate kinase activity
BHG40_RS00935	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_RS00940	COG0814	amino acid
BHG40_RS00945	COG1218	3'(2'),5'-bisphosphate nucleotidase
BHG40_RS00950	COG0494	nUDIX hydrolase
BHG40_RS00955	COG1011	Hydrolase
BHG40_RS00960	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHG40_RS00975	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
BHG40_RS00985	COG3156	type II secretion system protein K
BHG40_RS00990	COG4795	General secretion pathway protein
BHG40_RS00995	COG2165	general secretion pathway protein
BHG40_RS01005	COG2165	general secretion pathway protein
BHG40_RS01010	COG1459	type II secretion system
BHG40_RS01015	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHG40_RS01035	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BHG40_RS01040	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
BHG40_RS01060	COG0456	acetyltransferase
BHG40_RS01065	COG3133	Outer membrane lipoprotein
BHG40_RS01080	COG2771	luxR family
BHG40_RS01095	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
BHG40_RS01110	COG2213	PTS system mannitol-specific
BHG40_RS01110	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS01115	COG0246	Mannitol dehydrogenase
BHG40_RS01120	COG3722	fumarate hydratase activity
BHG40_RS01125	COG3263	regulation of cellular component size
BHG40_RS01130	COG0484	heat shock protein binding
BHG40_RS01150	COG1671	Belongs to the UPF0178 family
BHG40_RS01165	COG1988	membrane-bound metal-dependent
BHG40_RS01170	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHG40_RS01180	COG0513	Belongs to the DEAD box helicase family
BHG40_RS01205	COG1575	Belongs to the MenA family. Type 1 subfamily
BHG40_RS01210	COG1169	isochorismate synthase
BHG40_RS01215	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BHG40_RS01220	COG0596	Alpha beta hydrolase
BHG40_RS01225	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BHG40_RS01235	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_RS01245	COG5433	transposase activity
BHG40_RS01285	COG5433	transposase activity
BHG40_RS01305	COG2949	membrane
BHG40_RS01310	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BHG40_RS01320	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
BHG40_RS01325	COG5380	lipid catabolic process
BHG40_RS01340	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BHG40_RS01355	COG2873	o-acetylhomoserine
BHG40_RS01365	COG1979	alcohol dehydrogenase
BHG40_RS01385	COG4221	oxidoreductase activity
BHG40_RS01405	COG1285	pathogenesis
BHG40_RS01425	COG1368	sulfuric ester hydrolase activity
BHG40_RS01430	COG1522	sequence-specific DNA binding
BHG40_RS01440	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BHG40_RS01445	COG1418	mRNA catabolic process
BHG40_RS01450	COG1058	Belongs to the CinA family
BHG40_RS01450	COG1546	Belongs to the CinA family
BHG40_RS01460	COG1129	ABC transporter
BHG40_RS01460	COG0842	Transport permease protein
BHG40_RS01485	COG0561	phosphatase activity
BHG40_RS01490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BHG40_RS01500	COG0668	transmembrane transport
BHG40_RS01510	COG1011	Hydrolase
BHG40_RS01525	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BHG40_RS01530	COG0019	diaminopimelate decarboxylase activity
BHG40_RS01535	COG1965	Belongs to the frataxin family
BHG40_RS01540	COG0400	carboxylic ester hydrolase activity
BHG40_RS01545	COG3072	Adenylate cyclase
BHG40_RS01550	COG0181	hydroxymethylbilane synthase activity
BHG40_RS01560	COG2959	enzyme of heme biosynthesis
BHG40_RS01575	COG1494	fructose-1,6-bisphosphatase
BHG40_RS01625	COG3932	Exopolysaccharide synthesis, ExoD
BHG40_RS01630	COG0814	amino acid
BHG40_RS01635	COG5433	transposase activity
BHG40_RS01670	COG2022	thiamine diphosphate biosynthetic process
BHG40_RS01680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHG40_RS01685	COG0352	thiamine-phosphate diphosphorylase activity
BHG40_RS01690	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BHG40_RS01795	COG3328	transposase activity
BHG40_RS01810	COG2957	Belongs to the agmatine deiminase family
BHG40_RS01820	COG4221	oxidoreductase activity
BHG40_RS01835	COG1024	Enoyl-CoA hydratase
BHG40_RS01845	COG0110	maltose O-acetyltransferase activity
BHG40_RS01855	COG4166	transmembrane transport
BHG40_RS01870	COG1872	DUF167
BHG40_RS01875	COG0762	integral membrane protein
BHG40_RS01880	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BHG40_RS01885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BHG40_RS01900	COG3022	response to hydroperoxide
BHG40_RS01905	COG0513	Belongs to the DEAD box helicase family
BHG40_RS01910	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BHG40_RS01930	COG0735	belongs to the Fur family
BHG40_RS01935	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHG40_RS01950	COG0776	regulation of translation
BHG40_RS01955	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
BHG40_RS01980	COG0560	Phosphoserine phosphatase
BHG40_RS01990	COG0813	purine-nucleoside phosphorylase activity
BHG40_RS01995	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BHG40_RS02000	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
BHG40_RS02005	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BHG40_RS02020	COG0084	hydrolase, TatD family'
BHG40_RS02025	COG2165	general secretion pathway protein
BHG40_RS02040	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHG40_RS02045	COG0004	ammonium transporteR
BHG40_RS02080	COG0745	RESPONSE REGULATOR receiver
BHG40_RS02085	COG0642	Histidine kinase
BHG40_RS02090	COG0189	ligase activity
BHG40_RS02120	COG1639	'signal transduction protein
BHG40_RS02130	COG3700	Belongs to the class B bacterial acid phosphatase family
BHG40_RS02140	COG1366	Belongs to the anti-sigma-factor antagonist family
BHG40_RS02145	COG2172	sigma factor antagonist activity
BHG40_RS02150	COG0784	Response regulator, receiver
BHG40_RS02150	COG2205	protein histidine kinase activity
BHG40_RS02150	COG5002	protein histidine kinase activity
BHG40_RS02155	COG3437	response regulator, receiver
BHG40_RS02165	COG0477	Major facilitator Superfamily
BHG40_RS02180	COG0312	modulator of DNA gyrase
BHG40_RS02185	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHG40_RS02195	COG3164	Protein of unknown function
BHG40_RS02200	COG1530	ribonuclease E activity
BHG40_RS02205	COG0424	maF-like protein
BHG40_RS02210	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BHG40_RS02215	COG1792	Involved in formation and maintenance of cell shape
BHG40_RS02220	COG1077	Cell shape determining protein MreB Mrl
BHG40_RS02280	COG2200	EAL domain
BHG40_RS02280	COG2199	diguanylate cyclase activity
BHG40_RS02285	COG2264	protein methyltransferase activity
BHG40_RS02290	COG0387	Pfam Sodium calcium exchanger
BHG40_RS02295	COG2986	histidine ammonia-lyase
BHG40_RS02300	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BHG40_RS02305	COG0010	Belongs to the arginase family
BHG40_RS02310	COG1228	amidohydrolase
BHG40_RS02315	COG2188	Transcriptional regulator
BHG40_RS02320	COG0288	reversible hydration of carbon dioxide
BHG40_RS02330	COG2177	Part of the ABC transporter FtsEX involved in
BHG40_RS02335	COG2884	Cell division ATP-binding protein ftsE
BHG40_RS02340	COG0552	protein localization to endoplasmic reticulum
BHG40_RS02345	COG0742	ribosomal rna small subunit methyltransferase
BHG40_RS02370	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHG40_RS02375	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BHG40_RS02385	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHG40_RS02395	COG2095	MarC family integral membrane protein
BHG40_RS02405	COG1301	dicarboxylic acid transport
BHG40_RS02430	COG3714	YhhN family
BHG40_RS02465	COG2249	NAD(P)H dehydrogenase (quinone) activity
BHG40_RS02535	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BHG40_RS02540	COG3107	peptidoglycan biosynthetic process
BHG40_RS02550	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BHG40_RS02555	COG2823	Periplasmic or secreted lipoprotein
BHG40_RS02560	COG2969	positive regulation of protein catabolic process
BHG40_RS02565	COG0625	glutathione transferase activity
BHG40_RS02570	COG2857	Cytochrome c1
BHG40_RS02575	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BHG40_RS02580	COG0723	plastoquinol--plastocyanin reductase activity
BHG40_RS02585	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BHG40_RS02590	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BHG40_RS02595	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BHG40_RS02610	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BHG40_RS02645	COG3964	amidohydrolase
BHG40_RS02665	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS02670	COG1660	Displays ATPase and GTPase activities
BHG40_RS02675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS02690	COG1137	ATPase activity
BHG40_RS02695	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BHG40_RS02700	COG3117	lipopolysaccharide transmembrane transporter activity
BHG40_RS02705	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BHG40_RS02710	COG0517	IMP dehydrogenase activity
BHG40_RS02710	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BHG40_RS02715	COG1127	ABC transporter
BHG40_RS02720	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BHG40_RS02725	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHG40_RS02730	COG2854	intermembrane phospholipid transfer
BHG40_RS02740	COG5007	Belongs to the BolA IbaG family
BHG40_RS02745	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BHG40_RS02750	COG0312	modulator of DNA gyrase
BHG40_RS02755	COG3028	Belongs to the UPF0307 family
BHG40_RS02765	COG2926	Belongs to the UPF0265 family
BHG40_RS02795	COG1396	sequence-specific DNA binding
BHG40_RS02800	COG3135	benzoate transporter
BHG40_RS02830	COG3047	cAMP biosynthetic process
BHG40_RS02890	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BHG40_RS02895	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BHG40_RS02900	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BHG40_RS02905	COG0049	tRNA binding
BHG40_RS02910	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BHG40_RS02915	COG2168	tRNA wobble position uridine thiolation
BHG40_RS02920	COG2923	Belongs to the DsrF TusC family
BHG40_RS02935	COG2964	Protein conserved in bacteria
BHG40_RS02940	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BHG40_RS02945	COG0085	RNA polymerase activity
BHG40_RS02950	COG0222	ribosome binding
BHG40_RS02955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BHG40_RS02960	COG0081	regulation of translation
BHG40_RS02965	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BHG40_RS02970	COG0250	Participates in transcription elongation, termination and antitermination
BHG40_RS02985	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BHG40_RS03010	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BHG40_RS03015	COG0569	domain protein
BHG40_RS03020	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHG40_RS03025	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BHG40_RS03030	COG3005	denitrification pathway
BHG40_RS03035	COG0243	molybdopterin cofactor binding
BHG40_RS03065	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
BHG40_RS03070	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BHG40_RS03085	COG2204	response regulator
BHG40_RS03095	COG2205	protein histidine kinase activity
BHG40_RS03110	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS03115	COG0517	IMP dehydrogenase activity
BHG40_RS03115	COG0617	tRNA 3'-terminal CCA addition
BHG40_RS03115	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BHG40_RS03120	COG5413	integral membrane protein
BHG40_RS03130	COG1522	sequence-specific DNA binding
BHG40_RS03135	COG2502	aspartate--ammonia ligase
BHG40_RS03140	COG0542	response to heat
BHG40_RS03150	COG0564	pseudouridine synthase activity
BHG40_RS03155	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHG40_RS03160	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_RS03170	COG3681	Belongs to the UPF0597 family
BHG40_RS03175	COG2964	Protein conserved in bacteria
BHG40_RS03185	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BHG40_RS03190	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BHG40_RS03195	COG1979	alcohol dehydrogenase
BHG40_RS03205	COG3040	lipid binding
BHG40_RS03215	COG0688	phosphatidylethanolamine metabolic process
BHG40_RS03230	COG0540	Belongs to the ATCase OTCase family
BHG40_RS03235	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BHG40_RS03240	COG1438	arginine binding
BHG40_RS03245	COG1288	antiporter activity
BHG40_RS03250	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BHG40_RS03280	COG3328	transposase activity
BHG40_RS03290	COG4211	Belongs to the binding-protein-dependent transport system permease family
BHG40_RS03305	COG3250	beta-galactosidase activity
BHG40_RS03310	COG1609	Transcriptional regulator
BHG40_RS03315	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHG40_RS03325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHG40_RS03330	COG2017	converts alpha-aldose to the beta-anomer
BHG40_RS03335	COG0667	Aldo Keto reductase
BHG40_RS03340	COG1968	undecaprenyl-diphosphatase activity
BHG40_RS03350	COG1595	DNA-templated transcription, initiation
BHG40_RS03360	COG0018	arginyl-trna synthetase
BHG40_RS03370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BHG40_RS03375	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BHG40_RS03390	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHG40_RS03400	COG5433	transposase activity
BHG40_RS03405	COG2391	methyltransferase activity
BHG40_RS03445	COG0210	DNA helicase
BHG40_RS03450	COG1744	ABC transporter substrate-binding protein PnrA-like
BHG40_RS03455	COG3845	ABC transporter
BHG40_RS03460	COG4603	Belongs to the binding-protein-dependent transport system permease family
BHG40_RS03465	COG1079	Belongs to the binding-protein-dependent transport system permease family
BHG40_RS03470	COG0583	DNA-binding transcription factor activity
BHG40_RS03490	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BHG40_RS03495	COG0385	Bile acid
BHG40_RS03550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BHG40_RS03565	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BHG40_RS03570	COG3074	FtsZ-dependent cytokinesis
BHG40_RS03580	COG1045	serine acetyltransferase
BHG40_RS03590	COG0745	RESPONSE REGULATOR receiver
BHG40_RS03595	COG2205	protein histidine kinase activity
BHG40_RS03600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BHG40_RS03605	COG0534	Mate efflux family protein
BHG40_RS03620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BHG40_RS03625	COG2937	Belongs to the GPAT DAPAT family
BHG40_RS03630	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BHG40_RS03635	COG3161	chorismate lyase activity
BHG40_RS03640	COG1580	Controls the rotational direction of flagella during chemotaxis
BHG40_RS03670	COG1609	Transcriptional regulator
BHG40_RS03675	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS03690	COG1519	Transferase
BHG40_RS03695	COG0859	PFAM glycosyl transferase family 9
BHG40_RS03700	COG0463	Glycosyl transferase, family 2
BHG40_RS03705	COG0859	PFAM glycosyl transferase family 9
BHG40_RS03710	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BHG40_RS03715	COG2990	Protein conserved in bacteria
BHG40_RS03720	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BHG40_RS03730	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BHG40_RS03735	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BHG40_RS03740	COG2003	Belongs to the UPF0758 family
BHG40_RS03745	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BHG40_RS03750	COG0756	dUTP diphosphatase activity
BHG40_RS03755	COG1309	transcriptional regulator
BHG40_RS03760	COG0668	transmembrane transport
BHG40_RS03770	COG0166	Belongs to the GPI family
BHG40_RS03775	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BHG40_RS03780	COG0583	DNA-binding transcription factor activity
BHG40_RS03825	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BHG40_RS03830	COG4206	TonB-dependent receptor
BHG40_RS03835	COG0583	DNA-binding transcription factor activity
BHG40_RS03850	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BHG40_RS03855	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BHG40_RS03860	COG2223	nitrite transmembrane transporter activity
BHG40_RS03865	COG3279	Response regulator of the LytR AlgR family
BHG40_RS03870	COG3275	phosphorelay sensor kinase activity
BHG40_RS03880	COG2205	protein histidine kinase activity
BHG40_RS03880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS03890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS03890	COG2205	protein histidine kinase activity
BHG40_RS03895	COG5433	transposase activity
BHG40_RS03945	COG2081	HI0933 family
BHG40_RS03950	COG1528	Iron-storage protein
BHG40_RS03960	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BHG40_RS03965	COG0589	response to stress
BHG40_RS04005	COG3642	lipopolysaccharide core region biosynthetic process
BHG40_RS04010	COG0859	PFAM glycosyl transferase family 9
BHG40_RS04020	COG0194	GDP metabolic process
BHG40_RS04025	COG1758	RNA polymerase activity
BHG40_RS04030	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHG40_RS04035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHG40_RS04040	COG2267	carboxylic ester hydrolase activity
BHG40_RS04075	COG1309	transcriptional regulator
BHG40_RS04080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_RS04085	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHG40_RS04090	COG4191	Histidine kinase
BHG40_RS04090	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS04095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHG40_RS04120	COG2205	protein histidine kinase activity
BHG40_RS04125	COG0745	RESPONSE REGULATOR receiver
BHG40_RS04130	COG2814	Major facilitator Superfamily
BHG40_RS04145	COG3977	Valine--pyruvate aminotransferase
BHG40_RS04160	COG0071	Belongs to the small heat shock protein (HSP20) family
BHG40_RS04165	COG0071	Belongs to the small heat shock protein (HSP20) family
BHG40_RS04170	COG2378	regulation of single-species biofilm formation
BHG40_RS04195	COG0592	DNA-directed DNA polymerase activity
BHG40_RS04200	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BHG40_RS04215	COG1126	abc transporter atp-binding protein
BHG40_RS04220	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BHG40_RS04225	COG0594	ribonuclease P activity
BHG40_RS04230	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BHG40_RS04235	COG0706	membrane insertase activity
BHG40_RS04240	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BHG40_RS04255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHG40_RS04275	COG2375	cellular response to nickel ion
BHG40_RS04275	COG1132	(ABC) transporter
BHG40_RS04280	COG1132	(ABC) transporter
BHG40_RS04285	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_RS04290	COG4605	iron ion homeostasis
BHG40_RS04295	COG4604	ABC transporter, ATP-binding protein
BHG40_RS04300	COG4607	ABC-type enterochelin transport system periplasmic component
BHG40_RS04305	COG4774	siderophore transport
BHG40_RS04315	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHG40_RS04320	COG1120	ATPase activity
BHG40_RS04325	COG4615	Cyclic peptide transporter
BHG40_RS04330	COG4774	siderophore transport
BHG40_RS04335	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHG40_RS04340	COG0445	tRNA wobble uridine modification
BHG40_RS04345	COG0357	Ribosomal RNA small subunit methyltransferase G
BHG40_RS04350	COG1192	Involved in chromosome partitioning
BHG40_RS04355	COG1475	DNA binding
BHG40_RS04365	COG0356	it plays a direct role in the translocation of protons across the membrane
BHG40_RS04375	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BHG40_RS04385	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BHG40_RS04390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BHG40_RS04395	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BHG40_RS04400	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BHG40_RS04405	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BHG40_RS04410	COG4452	Inner membrane protein CreD
BHG40_RS04420	COG2205	protein histidine kinase activity
BHG40_RS04425	COG0745	RESPONSE REGULATOR receiver
BHG40_RS04430	COG1349	DNA-binding transcription factor activity
BHG40_RS04435	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BHG40_RS04440	COG2771	luxR family
BHG40_RS04450	COG0811	peptide transport
BHG40_RS04455	COG0811	peptide transport
BHG40_RS04460	COG0848	biopolymer transport protein
BHG40_RS04465	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
BHG40_RS04505	COG0402	S-adenosylhomocysteine deaminase activity
BHG40_RS04510	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BHG40_RS04520	COG3165	ubiquinone biosynthetic process from chorismate
BHG40_RS04525	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BHG40_RS04535	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BHG40_RS04540	COG0805	protein transport
BHG40_RS04545	COG0084	hydrolase, TatD family'
BHG40_RS04565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS04570	COG0742	ribosomal rna small subunit methyltransferase
BHG40_RS04580	COG0248	Ppx GppA phosphatase
BHG40_RS04585	COG0513	Belongs to the DEAD box helicase family
BHG40_RS04590	COG3118	belongs to the thioredoxin family
BHG40_RS04605	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BHG40_RS04630	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHG40_RS04670	COG1609	Transcriptional regulator
BHG40_RS04700	COG3328	transposase activity
BHG40_RS04735	COG2199	diguanylate cyclase activity
BHG40_RS04735	COG2200	EAL domain
BHG40_RS04735	COG2202	Pas domain
BHG40_RS04750	COG0814	amino acid
BHG40_RS04755	COG0348	domain, Protein
BHG40_RS04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_RS04775	COG3604	Transcriptional regulator
BHG40_RS04780	COG2188	Transcriptional regulator
BHG40_RS04800	COG0751	glycine-tRNA ligase activity
BHG40_RS04805	COG0752	glycyl-tRNA synthetase alpha subunit
BHG40_RS04815	COG2885	chlorophyll binding
BHG40_RS04820	COG0251	oxidation-reduction process
BHG40_RS04825	COG0425	Belongs to the sulfur carrier protein TusA family
BHG40_RS04850	COG0183	Belongs to the thiolase family
BHG40_RS04855	COG1024	Enoyl-CoA hydratase
BHG40_RS04855	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHG40_RS04860	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BHG40_RS04870	COG1739	Uncharacterized protein family UPF0029
BHG40_RS04875	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHG40_RS04880	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
BHG40_RS04910	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BHG40_RS04915	COG2166	iron-sulfur cluster assembly
BHG40_RS04920	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHG40_RS04925	COG0210	DNA helicase
BHG40_RS04940	COG1063	alcohol dehydrogenase
BHG40_RS04955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BHG40_RS04990	COG1561	YicC-like family, N-terminal region
BHG40_RS05000	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BHG40_RS05015	COG2203	Gaf domain
BHG40_RS05015	COG3706	GGDEF domain
BHG40_RS05015	COG5001	Diguanylate cyclase
BHG40_RS05015	COG4251	negative regulation of phosphorylation
BHG40_RS05020	COG3084	Protein conserved in bacteria
BHG40_RS05030	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BHG40_RS05035	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BHG40_RS05040	COG3639	organic phosphonate transmembrane transporter activity
BHG40_RS05045	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BHG40_RS05050	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BHG40_RS05060	COG1335	isochorismatase
BHG40_RS05070	COG1683	Conserved Protein
BHG40_RS05080	COG0606	chelatase, subunit chli
BHG40_RS05090	COG3978	acetolactate synthase activity
BHG40_RS05100	COG0129	dihydroxy-acid dehydratase activity
BHG40_RS05120	COG1309	transcriptional regulator
BHG40_RS05130	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BHG40_RS05135	COG0254	rRNA binding
BHG40_RS05140	COG0702	epimerase
BHG40_RS05145	COG0281	malic enzyme
BHG40_RS05155	COG2205	protein histidine kinase activity
BHG40_RS05160	COG0745	RESPONSE REGULATOR receiver
BHG40_RS05165	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHG40_RS05200	COG4310	Domain of unknown function (DUF2172)
BHG40_RS05210	COG5433	transposase activity
BHG40_RS05245	COG2089	acid synthase
BHG40_RS05255	COG1083	cytidylyl-transferase
BHG40_RS05275	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_RS05300	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BHG40_RS05305	COG1086	Polysaccharide biosynthesis protein
BHG40_RS05310	COG0366	Alpha amylase catalytic
BHG40_RS05325	COG0443	Heat shock 70 kDa protein
BHG40_RS05330	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHG40_RS05350	COG0174	glutamine synthetase
BHG40_RS05370	COG3842	ATPase activity
BHG40_RS05375	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHG40_RS05380	COG1177	transmembrane transport
BHG40_RS05385	COG2258	MOSC domain
BHG40_RS05405	COG2050	protein possibly involved in aromatic compounds catabolism
BHG40_RS05410	COG0514	ATP-dependent DNA helicase (RecQ)
BHG40_RS05420	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BHG40_RS05430	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BHG40_RS05435	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BHG40_RS05445	COG2239	Acts as a magnesium transporter
BHG40_RS05450	COG1648	precorrin-2 dehydrogenase activity
BHG40_RS05450	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHG40_RS05455	COG2116	formate transmembrane transporter activity
BHG40_RS05480	COG1280	lysine exporter protein (LysE YggA)
BHG40_RS05490	COG2962	Rard protein
BHG40_RS05500	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_RS05510	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BHG40_RS05520	COG0519	Catalyzes the synthesis of GMP from XMP
BHG40_RS05520	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BHG40_RS05525	COG0686	Belongs to the AlaDH PNT family
BHG40_RS05530	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_RS05555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BHG40_RS05560	COG0569	domain protein
BHG40_RS05565	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHG40_RS05565	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHG40_RS05570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BHG40_RS05575	COG0242	peptide deformylase activity
BHG40_RS05580	COG1652	LysM domain
BHG40_RS05585	COG0758	DNA mediated transformation
BHG40_RS05590	COG2922	Belongs to the Smg family
BHG40_RS05595	COG0551	DNA topoisomerase type I activity
BHG40_RS05605	COG0009	L-threonylcarbamoyladenylate synthase
BHG40_RS05610	COG0408	coproporphyrinogen oxidase activity
BHG40_RS05615	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BHG40_RS05625	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BHG40_RS05635	COG3078	GTPase activator activity
BHG40_RS05645	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHG40_RS05650	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BHG40_RS05655	COG2204	response regulator
BHG40_RS05660	COG3852	Histidine kinase
BHG40_RS05670	COG0174	glutamine synthetase
BHG40_RS05675	COG1217	gtp-binding protein TYPA
BHG40_RS05680	COG1295	ribonuclease BN
BHG40_RS05685	COG1490	D-aminoacyl-tRNA deacylase activity
BHG40_RS05695	COG0456	acetyltransferase
BHG40_RS05705	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BHG40_RS05710	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BHG40_RS05715	COG2610	gluconate transmembrane transporter activity
BHG40_RS05720	COG3265	gluconokinase activity
BHG40_RS05725	COG0129	dihydroxy-acid dehydratase activity
BHG40_RS05730	COG0800	Aldolase
BHG40_RS05740	COG1609	Transcriptional regulator
BHG40_RS05750	COG4942	peptidase
BHG40_RS05755	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BHG40_RS05760	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHG40_RS05765	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BHG40_RS05770	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BHG40_RS05775	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BHG40_RS05775	COG0316	Belongs to the HesB IscA family
BHG40_RS05780	COG1040	competence protein
BHG40_RS05785	COG0596	Alpha beta hydrolase
BHG40_RS05805	COG2183	response to ionizing radiation
BHG40_RS05810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHG40_RS05830	COG0051	transcription antitermination factor activity, RNA binding
BHG40_RS05835	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BHG40_RS05840	COG0088	Forms part of the polypeptide exit tunnel
BHG40_RS05845	COG0089	rRNA binding
BHG40_RS05850	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BHG40_RS05855	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BHG40_RS05860	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BHG40_RS05865	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BHG40_RS05870	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BHG40_RS05875	COG0255	Belongs to the universal ribosomal protein uL29 family
BHG40_RS05880	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BHG40_RS05885	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BHG40_RS05890	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BHG40_RS05895	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BHG40_RS05900	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BHG40_RS05905	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BHG40_RS05910	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BHG40_RS05915	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BHG40_RS05920	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BHG40_RS05925	COG1841	ribosomal large subunit assembly
BHG40_RS05930	COG0200	Binds to the 23S rRNA
BHG40_RS05935	COG0201	protein transport
BHG40_RS05940	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BHG40_RS05945	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BHG40_RS05950	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BHG40_RS05955	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BHG40_RS05960	COG0202	RNA polymerase activity
BHG40_RS05965	COG0203	ribosomal protein L17
BHG40_RS06015	COG2252	PERMEase
BHG40_RS06020	COG2376	Dihydroxyacetone kinase
BHG40_RS06025	COG1461	Dihydroxyacetone kinase
BHG40_RS06030	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHG40_RS06030	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
BHG40_RS06030	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS06040	COG3284	Transcriptional regulator
BHG40_RS06045	COG0628	permease
BHG40_RS06050	COG0494	nUDIX hydrolase
BHG40_RS06075	COG0753	catalase activity
BHG40_RS06080	COG1247	-acetyltransferase
BHG40_RS06100	COG2203	Gaf domain
BHG40_RS06100	COG2199	diguanylate cyclase activity
BHG40_RS06110	COG3842	ATPase activity
BHG40_RS06120	COG1176	ABC-type spermidine putrescine transport system, permease component I
BHG40_RS06145	COG0583	DNA-binding transcription factor activity
BHG40_RS06155	COG1741	Belongs to the pirin family
BHG40_RS06160	COG2259	Doxx family
BHG40_RS06165	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BHG40_RS06170	COG1074	ATP-dependent DNA helicase activity
BHG40_RS06175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BHG40_RS06195	COG0346	lactoylglutathione lyase activity
BHG40_RS06205	COG5433	transposase activity
BHG40_RS06225	COG0347	Belongs to the P(II) protein family
BHG40_RS06250	COG3706	GGDEF domain
BHG40_RS06260	COG1278	Cold shock
BHG40_RS06265	COG2199	diguanylate cyclase activity
BHG40_RS06270	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BHG40_RS06275	COG2197	response regulator
BHG40_RS06335	COG1677	Flagellar hook-basal body complex protein FliE
BHG40_RS06345	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BHG40_RS06370	COG2747	anti-sigma28 factor FlgM
BHG40_RS06380	COG1815	bacterial-type flagellum-dependent cell motility
BHG40_RS06390	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BHG40_RS06395	COG1749	Flagellar hook protein flgE
BHG40_RS06400	COG4786	Flagellar basal body rod
BHG40_RS06405	COG4786	Flagellar basal body rod
BHG40_RS06410	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BHG40_RS06415	COG1706	bacterial-type flagellum-dependent cell motility
BHG40_RS06425	COG4786	Flagellar basal body rod
BHG40_RS06425	COG1256	bacterial-type flagellum assembly
BHG40_RS06455	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHG40_RS06460	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BHG40_RS06485	COG1191	sigma factor activity
BHG40_RS06490	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHG40_RS06495	COG1360	Flagellar Motor Protein
BHG40_RS06505	COG1388	LysM domain
BHG40_RS06505	COG0741	lytic transglycosylase activity
BHG40_RS06515	COG2001	Belongs to the MraZ family
BHG40_RS06520	COG0275	rRNA processing
BHG40_RS06525	COG3116	cell division
BHG40_RS06530	COG0768	penicillin binding
BHG40_RS06540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BHG40_RS06545	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHG40_RS06550	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BHG40_RS06555	COG0772	Belongs to the SEDS family
BHG40_RS06560	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BHG40_RS06565	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BHG40_RS06570	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BHG40_RS06575	COG0849	cell division
BHG40_RS06580	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BHG40_RS06585	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BHG40_RS06595	COG0653	protein targeting
BHG40_RS06605	COG0494	nUDIX hydrolase
BHG40_RS06610	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BHG40_RS06615	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BHG40_RS06625	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BHG40_RS06635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHG40_RS06675	COG2186	Transcriptional regulator
BHG40_RS06680	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BHG40_RS06685	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHG40_RS06690	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHG40_RS06695	COG3447	MASE1 domain protein
BHG40_RS06695	COG5001	Diguanylate cyclase
BHG40_RS06695	COG5002	protein histidine kinase activity
BHG40_RS06705	COG0840	transmembrane signaling receptor activity
BHG40_RS06710	COG0840	transmembrane signaling receptor activity
BHG40_RS06720	COG1049	propionate catabolic process, 2-methylcitrate cycle
BHG40_RS06725	COG2200	EAL domain
BHG40_RS06730	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS06735	COG0583	DNA-binding transcription factor activity
BHG40_RS06745	COG1280	lysine exporter protein (LysE YggA)
BHG40_RS06755	COG0523	cobalamin synthesis protein
BHG40_RS06775	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BHG40_RS06780	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BHG40_RS06915	COG3314	Sporulation integral membrane protein YlbJ
BHG40_RS06925	COG0835	chemotaxis
BHG40_RS06925	COG0784	Response regulator, receiver
BHG40_RS06935	COG1444	tRNA N-acetyltransferase activity
BHG40_RS06960	COG1803	Methylglyoxal synthase
BHG40_RS06975	COG0252	asparaginase activity
BHG40_RS06985	COG1609	Transcriptional regulator
BHG40_RS06995	COG1940	carbohydrate kinase activity
BHG40_RS07000	COG1447	Phosphotransferase system cellobiose-specific component IIA
BHG40_RS07005	COG2723	6-phospho-beta-galactosidase activity
BHG40_RS07010	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_RS07010	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_RS07015	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_RS07020	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BHG40_RS07035	COG1263	PTS System
BHG40_RS07035	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_RS07040	COG0366	Alpha amylase catalytic
BHG40_RS07045	COG0110	maltose O-acetyltransferase activity
BHG40_RS07055	COG1757	Na H antiporter
BHG40_RS07090	COG0297	glycogen (starch) synthase activity
BHG40_RS07095	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BHG40_RS07100	COG2813	Specifically methylates the guanine in position
BHG40_RS07105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BHG40_RS07120	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHG40_RS07130	COG2995	paraquat-inducible protein a
BHG40_RS07135	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BHG40_RS07135	COG3008	intermembrane lipid transfer
BHG40_RS07140	COG3009	Protein conserved in bacteria
BHG40_RS07155	COG3240	lipase activity
BHG40_RS07160	COG3111	PFAM Bacterial OB fold (BOF) protein
BHG40_RS07170	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BHG40_RS07175	COG1194	a g-specific adenine glycosylase
BHG40_RS07185	COG3267	Type II secretory pathway component ExeA
BHG40_RS07185	COG3409	Peptidoglycan-binding domain 1 protein
BHG40_RS07190	COG0617	tRNA 3'-terminal CCA addition
BHG40_RS07195	COG0306	phosphate transporter
BHG40_RS07200	COG1392	Phosphate transport regulator
BHG40_RS07215	COG1560	Kdo2-lipid A biosynthetic process
BHG40_RS07220	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BHG40_RS07220	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BHG40_RS07225	COG1538	Outer membrane efflux protein
BHG40_RS07230	COG0494	nUDIX hydrolase
BHG40_RS07235	COG3151	Protein conserved in bacteria
BHG40_RS07245	COG3150	esterase
BHG40_RS07250	COG1051	belongs to the nudix hydrolase family
BHG40_RS07330	COG2259	Doxx family
BHG40_RS07335	COG3118	belongs to the thioredoxin family
BHG40_RS07355	COG0204	Acyl-transferase
BHG40_RS07375	COG2827	Endonuclease containing a URI domain
BHG40_RS07390	COG1573	uracil-dna glycosylase
BHG40_RS07400	COG0583	DNA-binding transcription factor activity
BHG40_RS07405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BHG40_RS07410	COG1121	(ABC) transporter
BHG40_RS07415	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
BHG40_RS07435	COG0739	heme binding
BHG40_RS07445	COG3068	Protein conserved in bacteria
BHG40_RS07465	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BHG40_RS07485	COG0798	PFAM Bile acid sodium symporter
BHG40_RS07490	COG1393	Belongs to the ArsC family
BHG40_RS07500	COG2072	flavoprotein involved in K transport
BHG40_RS07510	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BHG40_RS07520	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BHG40_RS07525	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BHG40_RS07535	COG0137	argininosuccinate synthase activity
BHG40_RS07540	COG0165	Argininosuccinate lyase
BHG40_RS07545	COG0583	DNA-binding transcription factor activity
BHG40_RS07555	COG1942	4-Oxalocrotonate Tautomerase
BHG40_RS07585	COG0110	maltose O-acetyltransferase activity
BHG40_RS07590	COG3174	membrane
BHG40_RS07595	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BHG40_RS07605	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BHG40_RS07615	COG4208	sulfate ABC transporter
BHG40_RS07620	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BHG40_RS07625	COG0583	DNA-binding transcription factor activity
BHG40_RS07630	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BHG40_RS07635	COG0765	amino acid transport
BHG40_RS07645	COG1126	abc transporter atp-binding protein
BHG40_RS07650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS07655	COG3397	chitin binding
BHG40_RS07660	COG0840	transmembrane signaling receptor activity
BHG40_RS07695	COG0726	polysaccharide deacetylase
BHG40_RS07695	COG1649	PFAM Uncharacterised BCR, COG1649
BHG40_RS07700	COG1215	transferase activity, transferring glycosyl groups
BHG40_RS07745	COG1328	CTP reductase activity
BHG40_RS07750	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BHG40_RS07770	COG1448	Aminotransferase
BHG40_RS07810	COG0513	Belongs to the DEAD box helicase family
BHG40_RS07825	COG3568	Endonuclease Exonuclease Phosphatase
BHG40_RS07830	COG0840	transmembrane signaling receptor activity
BHG40_RS07845	COG3112	Uncharacterised protein family (UPF0231)
BHG40_RS07850	COG3835	regulator
BHG40_RS07855	COG2610	gluconate transmembrane transporter activity
BHG40_RS07860	COG1929	Belongs to the glycerate kinase type-1 family
BHG40_RS07880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BHG40_RS07895	COG0347	Belongs to the P(II) protein family
BHG40_RS07900	COG1840	ABC-type Fe3 transport system, periplasmic component
BHG40_RS07910	COG3842	ATPase activity
BHG40_RS07915	COG2837	iron assimilation
BHG40_RS07920	COG1438	arginine binding
BHG40_RS07925	COG1126	abc transporter atp-binding protein
BHG40_RS07930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS07935	COG4215	(ABC) transporter
BHG40_RS07940	COG4160	amino acid transport
BHG40_RS07945	COG0039	L-malate dehydrogenase activity
BHG40_RS07950	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BHG40_RS07955	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHG40_RS07955	COG1017	nitric oxide dioxygenase activity
BHG40_RS07960	COG1959	2 iron, 2 sulfur cluster binding
BHG40_RS07965	COG4536	flavin adenine dinucleotide binding
BHG40_RS07970	COG4137	Cytochrome C assembly protein
BHG40_RS07975	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BHG40_RS07980	COG0228	four-way junction DNA binding
BHG40_RS07985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BHG40_RS07990	COG0336	Belongs to the RNA methyltransferase TrmD family
BHG40_RS07995	COG0335	large ribosomal subunit rRNA binding
BHG40_RS08005	COG3066	DNA modification
BHG40_RS08010	COG1051	belongs to the nudix hydrolase family
BHG40_RS08020	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BHG40_RS08025	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BHG40_RS08030	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BHG40_RS08040	COG0583	DNA-binding transcription factor activity
BHG40_RS08045	COG0640	Transcriptional regulator
BHG40_RS08050	COG0268	Binds directly to 16S ribosomal RNA
BHG40_RS08055	COG0728	peptidoglycan biosynthetic process
BHG40_RS08060	COG0196	riboflavin kinase activity
BHG40_RS08065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BHG40_RS08070	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BHG40_RS08075	COG1047	Peptidyl-prolyl cis-trans
BHG40_RS08080	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BHG40_RS08120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHG40_RS08120	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BHG40_RS08135	COG1854	S-ribosylhomocysteine lyase activity
BHG40_RS08140	COG3706	GGDEF domain
BHG40_RS08145	COG0557	exoribonuclease II activity
BHG40_RS08150	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BHG40_RS08160	COG2153	protein acetylation
BHG40_RS08180	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BHG40_RS08185	COG1914	H( )-stimulated, divalent metal cation uptake system
BHG40_RS08190	COG0360	Binds together with S18 to 16S ribosomal RNA
BHG40_RS08195	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BHG40_RS08200	COG0359	binds to the 23S rRNA
BHG40_RS08230	COG1064	alcohol dehydrogenase
BHG40_RS08235	COG1238	metal cluster binding
BHG40_RS08240	COG0612	Peptidase, M16
BHG40_RS08245	COG2918	glutathione biosynthetic process
BHG40_RS08255	COG1022	Amp-dependent synthetase and ligase
BHG40_RS08265	COG0456	acetyltransferase
BHG40_RS08275	COG0714	Associated with various cellular activities
BHG40_RS08305	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BHG40_RS08315	COG1902	pentaerythritol trinitrate reductase activity
BHG40_RS08325	COG0442	prolyl-tRNA aminoacylation
BHG40_RS08335	COG0632	four-way junction helicase activity
BHG40_RS08340	COG2255	four-way junction helicase activity
BHG40_RS08345	COG1271	oxidase subunit
BHG40_RS08350	COG1294	oxidase, subunit
BHG40_RS08355	COG4890	Cyd operon protein YbgT
BHG40_RS08360	COG3790	cyd operon protein YbgE
BHG40_RS08365	COG0824	Thioesterase
BHG40_RS08370	COG0811	peptide transport
BHG40_RS08385	COG0823	Involved in the tonB-independent uptake of proteins
BHG40_RS08390	COG2885	chlorophyll binding
BHG40_RS08395	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BHG40_RS08460	COG0840	transmembrane signaling receptor activity
BHG40_RS08465	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BHG40_RS08470	COG0676	glucose-6-phosphate 1-epimerase activity
BHG40_RS08475	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHG40_RS08480	COG1640	4-alpha-glucanotransferase
BHG40_RS08485	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BHG40_RS08505	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHG40_RS08510	COG4991	sh3 domain protein
BHG40_RS08515	COG0506	proline dehydrogenase activity
BHG40_RS08515	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BHG40_RS08515	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BHG40_RS08525	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BHG40_RS08530	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BHG40_RS08535	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BHG40_RS08540	COG0163	prenyltransferase activity
BHG40_RS08555	COG1131	(ABC) transporter
BHG40_RS08560	COG0842	Transport permease protein
BHG40_RS08570	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BHG40_RS08575	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BHG40_RS08580	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BHG40_RS08585	COG0617	tRNA 3'-terminal CCA addition
BHG40_RS08590	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHG40_RS08595	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BHG40_RS08600	COG1489	DNA binding
BHG40_RS08610	COG1643	Atp-dependent helicase
BHG40_RS08615	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHG40_RS08620	COG0346	lactoylglutathione lyase activity
BHG40_RS08630	COG2076	Multidrug Resistance protein
BHG40_RS08635	COG0583	DNA-binding transcription factor activity
BHG40_RS08640	COG3437	response regulator, receiver
BHG40_RS08640	COG0784	Response regulator, receiver
BHG40_RS08650	COG0671	phosphoesterase, PA-phosphatase related
BHG40_RS08665	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BHG40_RS08670	COG0038	chloride channel
BHG40_RS08680	COG0316	Belongs to the HesB IscA family
BHG40_RS08710	COG2816	NAD+ diphosphatase activity
BHG40_RS08715	COG2205	protein histidine kinase activity
BHG40_RS08720	COG0745	RESPONSE REGULATOR receiver
BHG40_RS08725	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_RS08740	COG1505	serine-type exopeptidase activity
BHG40_RS08745	COG2982	Protein involved in outer membrane biogenesis
BHG40_RS08755	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS08795	COG1349	DNA-binding transcription factor activity
BHG40_RS08800	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BHG40_RS08820	COG2130	NADP-dependent
BHG40_RS08825	COG1764	response to oxidative stress
BHG40_RS08830	COG1846	Transcriptional regulator
BHG40_RS08860	COG0561	phosphatase activity
BHG40_RS08885	COG0733	neurotransmitter:sodium symporter activity
BHG40_RS08910	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHG40_RS08925	COG1794	racemase activity, acting on amino acids and derivatives
BHG40_RS08935	COG2731	YhcH YjgK YiaL family protein
BHG40_RS08945	COG0668	transmembrane transport
BHG40_RS08950	COG1376	ErfK ybiS ycfS ynhG family protein
BHG40_RS08955	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHG40_RS08990	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BHG40_RS09000	COG0488	(ABC) transporter
BHG40_RS09005	COG0517	IMP dehydrogenase activity
BHG40_RS09005	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BHG40_RS09010	COG1585	Membrane protein implicated in regulation of membrane protease activity
BHG40_RS09015	COG0330	HflC and HflK could
BHG40_RS09020	COG1648	precorrin-2 dehydrogenase activity
BHG40_RS09020	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BHG40_RS09025	COG0175	sulfate reduction
BHG40_RS09030	COG2895	sulfate adenylyltransferase (ATP) activity
BHG40_RS09035	COG0471	metal ion transport
BHG40_RS09035	COG3273	potassium ion transport
BHG40_RS09040	COG0529	Catalyzes the synthesis of activated sulfate
BHG40_RS09045	COG5433	transposase activity
BHG40_RS09095	COG1136	(ABC) transporter
BHG40_RS09110	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
BHG40_RS09135	COG1940	carbohydrate kinase activity
BHG40_RS09140	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BHG40_RS09145	COG0126	phosphoglycerate kinase activity
BHG40_RS09150	COG0191	fructose-bisphosphate aldolase activity
BHG40_RS09155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHG40_RS09205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BHG40_RS09210	COG1595	DNA-templated transcription, initiation
BHG40_RS09215	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
BHG40_RS09230	COG0481	GTPase activity
BHG40_RS09240	COG0571	ribonuclease III activity
BHG40_RS09250	COG1381	Involved in DNA repair and RecF pathway recombination
BHG40_RS09255	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BHG40_RS09260	COG3023	N-Acetylmuramoyl-L-alanine amidase
BHG40_RS09265	COG4807	Protein conserved in bacteria
BHG40_RS09275	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BHG40_RS09280	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BHG40_RS09285	COG3956	TIGRFAM MazG family protein
BHG40_RS09290	COG0504	CTP synthase activity
BHG40_RS09295	COG0148	phosphopyruvate hydratase activity
BHG40_RS09300	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BHG40_RS09305	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BHG40_RS09315	COG0585	pseudouridine synthase activity
BHG40_RS09320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BHG40_RS09325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BHG40_RS09330	COG1238	metal cluster binding
BHG40_RS09335	COG4942	peptidase
BHG40_RS09335	COG1388	LysM domain
BHG40_RS09345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BHG40_RS09350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BHG40_RS09355	COG1610	YqeY-like protein
BHG40_RS09360	COG0358	DNA primase activity
BHG40_RS09365	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BHG40_RS09405	COG0151	Belongs to the GarS family
BHG40_RS09410	COG0138	bifunctional purine biosynthesis protein purh
BHG40_RS09420	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BHG40_RS09425	COG3036	rescue of stalled ribosome
BHG40_RS09430	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BHG40_RS09435	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BHG40_RS09445	COG0673	inositol 2-dehydrogenase activity
BHG40_RS09460	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_RS09465	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_RS09470	COG3227	Zinc metalloprotease (Elastase)
BHG40_RS09480	COG0477	Major facilitator Superfamily
BHG40_RS09490	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
BHG40_RS09495	COG1027	Aspartate ammonia-lyase
BHG40_RS09500	COG3030	protein affecting phage T7 exclusion by the F plasmid
BHG40_RS09505	COG0534	Mate efflux family protein
BHG40_RS09510	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BHG40_RS09515	COG0459	protein refolding
BHG40_RS09525	COG3300	MHYT domain
BHG40_RS09525	COG5001	Diguanylate cyclase
BHG40_RS09535	COG0564	pseudouridine synthase activity
BHG40_RS09570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHG40_RS09580	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BHG40_RS09585	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
BHG40_RS09590	COG1178	ABC-type Fe3 transport system permease component
BHG40_RS09595	COG4143	(ABC) transporter
BHG40_RS09610	COG0066	3-isopropylmalate dehydratase activity
BHG40_RS09615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BHG40_RS09620	COG0473	3-isopropylmalate dehydrogenase activity
BHG40_RS09625	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BHG40_RS09635	COG0671	phosphoesterase, PA-phosphatase related
BHG40_RS09650	COG0028	Belongs to the TPP enzyme family
BHG40_RS09655	COG0440	acetolactate synthase activity
BHG40_RS09660	COG0280	phosphate acetyltransferase
BHG40_RS09660	COG0857	belongs to the CobB CobQ family
BHG40_RS09665	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BHG40_RS09675	COG3013	Belongs to the UPF0304 family
BHG40_RS09680	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BHG40_RS09685	COG2716	regulation of RNA biosynthetic process
BHG40_RS09695	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BHG40_RS09700	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BHG40_RS09735	COG5002	protein histidine kinase activity
BHG40_RS09735	COG2198	Histidine kinase
BHG40_RS09735	COG0784	Response regulator, receiver
BHG40_RS09760	COG0840	transmembrane signaling receptor activity
BHG40_RS09770	COG1464	Belongs to the NlpA lipoprotein family
BHG40_RS09775	COG2011	ABC-type metal ion transport system permease component
BHG40_RS09780	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BHG40_RS09800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BHG40_RS09800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BHG40_RS09805	COG0802	atpase or kinase
BHG40_RS09815	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BHG40_RS09820	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BHG40_RS09825	COG1923	regulation of RNA biosynthetic process
BHG40_RS09830	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BHG40_RS09835	COG0330	HflC and HflK could
BHG40_RS09840	COG0330	HflC and HflK could
BHG40_RS09845	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
BHG40_RS09850	COG0142	geranyltranstransferase activity
BHG40_RS09855	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BHG40_RS09860	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BHG40_RS09865	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BHG40_RS09870	COG3314	Sporulation integral membrane protein YlbJ
BHG40_RS09875	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_RS09895	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BHG40_RS09910	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BHG40_RS09915	COG2967	ApaG domain
BHG40_RS09920	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BHG40_RS09925	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BHG40_RS09935	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BHG40_RS09940	COG3178	'Phosphotransferase
BHG40_RS09945	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BHG40_RS09950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BHG40_RS09955	COG2252	PERMEase
BHG40_RS09965	COG0488	(ABC) transporter
BHG40_RS09990	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_RS10000	COG3721	Heme iron utilization protein
BHG40_RS10005	COG0748	coenzyme F420 binding
BHG40_RS10050	COG3397	chitin binding
BHG40_RS10065	COG1765	OsmC-like protein
BHG40_RS10080	COG3954	Phosphoribulokinase
BHG40_RS10090	COG2076	Multidrug Resistance protein
BHG40_RS10095	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BHG40_RS10100	COG0726	polysaccharide deacetylase
BHG40_RS10110	COG0463	Glycosyl transferase, family 2
BHG40_RS10135	COG3089	Belongs to the UPF0270 family
BHG40_RS10140	COG5001	Diguanylate cyclase
BHG40_RS10140	COG3706	GGDEF domain
BHG40_RS10140	COG2203	Gaf domain
BHG40_RS10140	COG4251	negative regulation of phosphorylation
BHG40_RS10145	COG0429	hydrolase of the alpha beta-hydrolase fold
BHG40_RS10150	COG0835	chemotaxis
BHG40_RS10150	COG0784	Response regulator, receiver
BHG40_RS10160	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
BHG40_RS10165	COG1047	Peptidyl-prolyl cis-trans
BHG40_RS10180	COG0545	Peptidyl-prolyl cis-trans isomerase
BHG40_RS10185	COG2204	response regulator
BHG40_RS10205	COG0737	Belongs to the 5'-nucleotidase family
BHG40_RS10210	COG2200	EAL domain
BHG40_RS10235	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHG40_RS10240	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHG40_RS10245	COG0826	peptidase U32
BHG40_RS10250	COG2203	Gaf domain
BHG40_RS10250	COG2200	EAL domain
BHG40_RS10250	COG2199	diguanylate cyclase activity
BHG40_RS10295	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BHG40_RS10300	COG2201	protein-glutamate methylesterase activity
BHG40_RS10330	COG2916	Histone family protein nucleoid-structuring protein H-NS
BHG40_RS10335	COG3328	transposase activity
BHG40_RS10345	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_RS10350	COG2375	cellular response to nickel ion
BHG40_RS10355	COG1538	Outer membrane efflux protein
BHG40_RS10360	COG1136	(ABC) transporter
BHG40_RS10360	COG0577	efflux transmembrane transporter activity
BHG40_RS10365	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_RS10375	COG1227	inorganic diphosphatase activity
BHG40_RS10380	COG0497	DNA recombination
BHG40_RS10385	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BHG40_RS10390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BHG40_RS10395	COG0443	Heat shock 70 kDa protein
BHG40_RS10400	COG0484	heat shock protein binding
BHG40_RS10430	COG1285	pathogenesis
BHG40_RS10480	COG0095	Lipoate-protein ligase
BHG40_RS10520	COG0708	Exodeoxyribonuclease III
BHG40_RS10580	COG2814	Major facilitator Superfamily
BHG40_RS10585	COG0109	protoheme IX farnesyltransferase activity
BHG40_RS10595	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BHG40_RS10600	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BHG40_RS10640	COG1609	Transcriptional regulator
BHG40_RS10645	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_RS10645	COG1263	PTS System
BHG40_RS10665	COG5433	transposase activity
BHG40_RS10680	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_RS10695	COG2207	Transcriptional regulator
BHG40_RS10700	COG0538	isocitrate dehydrogenase activity
BHG40_RS10745	COG0582	viral genome integration into host DNA
BHG40_RS10755	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BHG40_RS10760	COG2867	negative regulation of translational initiation
BHG40_RS10765	COG2914	Belongs to the UPF0125 (RnfH) family
BHG40_RS10770	COG0702	epimerase
BHG40_RS10775	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHG40_RS10805	COG4964	Belongs to the GSP D family
BHG40_RS10815	COG2894	cell division
BHG40_RS10855	COG1454	alcohol dehydrogenase
BHG40_RS10870	COG1957	nucleoside hydrolase
BHG40_RS10890	COG0840	transmembrane signaling receptor activity
BHG40_RS10895	COG1280	lysine exporter protein (LysE YggA)
BHG40_RS10905	COG5433	transposase activity
BHG40_RS10925	COG3263	regulation of cellular component size
BHG40_RS10935	COG1876	peptidase activity
BHG40_RS10940	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BHG40_RS10945	COG1393	Belongs to the ArsC family
BHG40_RS10950	COG0583	DNA-binding transcription factor activity
BHG40_RS10970	COG0017	Asparaginyl-tRNA synthetase
BHG40_RS10990	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BHG40_RS10995	COG0156	8-amino-7-oxononanoate synthase activity
BHG40_RS11000	COG1073	alpha beta
BHG40_RS11000	COG2226	methyltransferase
BHG40_RS11005	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BHG40_RS11010	COG0501	Belongs to the peptidase M48B family
BHG40_RS11020	COG3217	Mosc domain protein beta barrel domain protein
BHG40_RS11020	COG0633	Ferredoxin
BHG40_RS11020	COG0633	Ferredoxin
BHG40_RS11020	COG3217	Mosc domain protein beta barrel domain protein
BHG40_RS11035	COG1013	pyruvate-flavodoxin oxidoreductase activity
BHG40_RS11035	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BHG40_RS11035	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BHG40_RS11035	COG0674	pyruvate-flavodoxin oxidoreductase activity
BHG40_RS11040	COG2841	Protein conserved in bacteria
BHG40_RS11050	COG0534	Mate efflux family protein
BHG40_RS11090	COG1309	transcriptional regulator
BHG40_RS11105	COG0791	NLP P60 protein
BHG40_RS11115	COG0583	DNA-binding transcription factor activity
BHG40_RS11125	COG2198	Histidine kinase
BHG40_RS11125	COG0643	Histidine kinase
BHG40_RS11125	COG0784	Response regulator, receiver
BHG40_RS11130	COG2201	protein-glutamate methylesterase activity
BHG40_RS11135	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHG40_RS11140	COG1360	Flagellar Motor Protein
BHG40_RS11145	COG1192	Involved in chromosome partitioning
BHG40_RS11155	COG0835	chemotaxis
BHG40_RS11170	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHG40_RS11175	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHG40_RS11180	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BHG40_RS11190	COG1138	Cytochrome C-type biogenesis protein
BHG40_RS11195	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BHG40_RS11200	COG4235	cytochrome complex assembly
BHG40_RS11200	COG3088	subunit of a heme lyase
BHG40_RS11220	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BHG40_RS11225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHG40_RS11225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHG40_RS11240	COG0259	pyridoxamine-phosphate oxidase activity
BHG40_RS11275	COG2850	peptidyl-arginine hydroxylation
BHG40_RS11280	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BHG40_RS11285	COG2915	High frequency lysogenization protein hflD homolog
BHG40_RS11290	COG0482	sulfurtransferase activity
BHG40_RS11310	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_RS11320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_RS11320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_RS11320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS11375	COG0159	tryptophan synthase activity
BHG40_RS11380	COG0133	tryptophan synthase activity
BHG40_RS11385	COG0135	phosphoribosylanthranilate isomerase activity
BHG40_RS11385	COG0134	indole-3-glycerol-phosphate synthase activity
BHG40_RS11390	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHG40_RS11395	COG0512	Glutamine amidotransferase of anthranilate synthase
BHG40_RS11395	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BHG40_RS11400	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHG40_RS11410	COG0009	L-threonylcarbamoyladenylate synthase
BHG40_RS11420	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BHG40_RS11430	COG1946	Acyl-CoA thioesterase
BHG40_RS11445	COG1309	transcriptional regulator
BHG40_RS11450	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_RS11470	COG1091	dTDP-4-dehydrorhamnose reductase activity
BHG40_RS11490	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BHG40_RS11495	COG1459	type II secretion system
BHG40_RS11550	COG0438	transferase activity, transferring glycosyl groups
BHG40_RS11575	COG5433	transposase activity
BHG40_RS11580	COG3273	potassium ion transport
BHG40_RS11580	COG0471	metal ion transport
BHG40_RS11590	COG5433	transposase activity
BHG40_RS11605	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BHG40_RS11625	COG5433	transposase activity
BHG40_RS11640	COG3132	Protein of unknown function, DUF480
BHG40_RS11695	COG1278	Cold shock
BHG40_RS11735	COG0697	spore germination
BHG40_RS11765	COG4166	transmembrane transport
BHG40_RS11770	COG0622	Phosphoesterase
BHG40_RS11790	COG0784	Response regulator, receiver
BHG40_RS11790	COG0835	chemotaxis
BHG40_RS11795	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BHG40_RS11800	COG1815	bacterial-type flagellum-dependent cell motility
BHG40_RS11820	COG4787	bacterial-type flagellum-dependent cell motility
BHG40_RS11830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BHG40_RS11865	COG2239	Acts as a magnesium transporter
BHG40_RS11870	COG0248	Ppx GppA phosphatase
BHG40_RS11875	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BHG40_RS11905	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BHG40_RS11910	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BHG40_RS11915	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BHG40_RS11920	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BHG40_RS11940	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BHG40_RS11950	COG0590	tRNA wobble adenosine to inosine editing
BHG40_RS11955	COG0573	inorganic phosphate transmembrane transporter activity
BHG40_RS11960	COG0581	inorganic phosphate transmembrane transporter activity
BHG40_RS11965	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BHG40_RS11970	COG0704	Plays a role in the regulation of phosphate uptake
BHG40_RS11975	COG1253	flavin adenine dinucleotide binding
BHG40_RS11990	COG0531	amino acid
BHG40_RS12000	COG1126	abc transporter atp-binding protein
BHG40_RS12005	COG0765	amino acid transport
BHG40_RS12010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS12015	COG3706	GGDEF domain
BHG40_RS12020	COG2271	Major facilitator Superfamily
BHG40_RS12035	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BHG40_RS12060	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BHG40_RS12075	COG1199	ATP-dependent helicase activity
BHG40_RS12090	COG1448	Aminotransferase
BHG40_RS12095	COG0433	COG0433 Predicted ATPase
BHG40_RS12110	COG0658	competence protein
BHG40_RS12110	COG2333	competence protein COMEC
BHG40_RS12115	COG1132	(ABC) transporter
BHG40_RS12120	COG1663	tetraacyldisaccharide 4'-kinase activity
BHG40_RS12125	COG2835	tetraacyldisaccharide 4'-kinase activity
BHG40_RS12130	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BHG40_RS12135	COG2197	response regulator
BHG40_RS12140	COG0322	excinuclease ABC activity
BHG40_RS12180	COG2261	transglycosylase associated protein
BHG40_RS12185	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_RS12195	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHG40_RS12225	COG2199	diguanylate cyclase activity
BHG40_RS12225	COG2203	Gaf domain
BHG40_RS12255	COG2119	membrane
BHG40_RS12300	COG2205	protein histidine kinase activity
BHG40_RS12300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS12310	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
BHG40_RS12315	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_RS12320	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BHG40_RS12325	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BHG40_RS12330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BHG40_RS12335	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BHG40_RS12350	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BHG40_RS12355	COG0505	Belongs to the CarA family
BHG40_RS12360	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BHG40_RS12365	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BHG40_RS12395	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_RS12400	COG0513	Belongs to the DEAD box helicase family
BHG40_RS12440	COG5433	transposase activity
BHG40_RS12445	COG0069	glutamate synthase activity
BHG40_RS12445	COG0067	glutamate synthase
BHG40_RS12445	COG0070	glutamate synthase
BHG40_RS12450	COG0493	'glutamate synthase
BHG40_RS12465	COG0789	Transcriptional regulator
BHG40_RS12505	COG1252	NADH dehydrogenase
BHG40_RS12510	COG0393	Putative heavy-metal-binding
BHG40_RS12520	COG1619	proteins homologs of microcin C7 resistance protein MccF
BHG40_RS12525	COG1368	sulfuric ester hydrolase activity
BHG40_RS12535	COG0527	aspartate kinase activity
BHG40_RS12540	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BHG40_RS12540	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BHG40_RS12545	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHG40_RS12600	COG1285	pathogenesis
BHG40_RS12615	COG0577	efflux transmembrane transporter activity
BHG40_RS12620	COG1136	(ABC) transporter
BHG40_RS12635	COG2814	Major facilitator Superfamily
BHG40_RS12660	COG0672	)-iron permease
BHG40_RS12730	COG0574	Belongs to the PEP-utilizing enzyme family
BHG40_RS12730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BHG40_RS12765	COG5433	transposase activity
BHG40_RS12790	COG0671	phosphoesterase, PA-phosphatase related
BHG40_RS12800	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHG40_RS12810	COG0101	tRNA pseudouridine synthase activity
BHG40_RS12815	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BHG40_RS12820	COG0285	dihydrofolate synthase activity
BHG40_RS12825	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
BHG40_RS12830	COG2920	part of a sulfur-relay system
BHG40_RS12835	COG1289	transmembrane transporter activity
BHG40_RS12840	COG0670	Belongs to the BI1 family
BHG40_RS12850	COG0840	transmembrane signaling receptor activity
BHG40_RS12870	COG0564	pseudouridine synthase activity
BHG40_RS12895	COG0625	glutathione transferase activity
BHG40_RS12900	COG0625	glutathione transferase activity
BHG40_RS12925	COG0367	asparagine synthase
BHG40_RS12935	COG4651	solute:proton antiporter activity
BHG40_RS12935	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHG40_RS12940	COG0647	UMP catabolic process
BHG40_RS12950	COG1902	pentaerythritol trinitrate reductase activity
BHG40_RS12955	COG1253	flavin adenine dinucleotide binding
BHG40_RS12965	COG0277	FAD linked oxidase domain protein
BHG40_RS12965	COG0247	lactate metabolic process
BHG40_RS12975	COG2050	protein possibly involved in aromatic compounds catabolism
BHG40_RS12980	COG0513	Belongs to the DEAD box helicase family
BHG40_RS12990	COG3300	MHYT domain
BHG40_RS12990	COG5001	Diguanylate cyclase
BHG40_RS12995	COG2056	Na+-H+ antiporter family
BHG40_RS13000	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHG40_RS13015	COG0346	lactoylglutathione lyase activity
BHG40_RS13020	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BHG40_RS13025	COG4660	Part of a membrane complex involved in electron transport
BHG40_RS13030	COG4659	FMN binding
BHG40_RS13035	COG4658	electron transport chain
BHG40_RS13045	COG2878	Part of a membrane complex involved in electron transport
BHG40_RS13050	COG4657	Part of a membrane complex involved in electron transport
BHG40_RS13055	COG0697	spore germination
BHG40_RS13105	COG0659	secondary active sulfate transmembrane transporter activity
BHG40_RS13170	COG3829	transcription factor binding
BHG40_RS13230	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BHG40_RS13235	COG1278	Cold shock
BHG40_RS13240	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BHG40_RS13245	COG0542	response to heat
BHG40_RS13255	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BHG40_RS13260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BHG40_RS13265	COG3134	Outer membrane lipoprotein
BHG40_RS13275	COG0492	ferredoxin-NADP+ reductase activity
BHG40_RS13295	COG1674	ftsk spoiiie
BHG40_RS13295	COG0531	amino acid
BHG40_RS13300	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BHG40_RS13305	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BHG40_RS13310	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BHG40_RS13315	COG1286	toxin biosynthetic process
BHG40_RS13320	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BHG40_RS13330	COG4172	Belongs to the ABC transporter superfamily
BHG40_RS13335	COG4172	Belongs to the ABC transporter superfamily
BHG40_RS13340	COG4171	peptide transport system, permease
BHG40_RS13345	COG4168	peptide transport system, permease
BHG40_RS13355	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
BHG40_RS13360	COG1842	Phage shock protein A
BHG40_RS13375	COG3106	COG3106 Predicted ATPase
BHG40_RS13380	COG3768	UPF0283 membrane protein
BHG40_RS13390	COG2154	pterin-4-alpha-carbinolamine dehydratase
BHG40_RS13405	COG2199	diguanylate cyclase activity
BHG40_RS13415	COG0861	Integral membrane protein TerC family
BHG40_RS13430	COG1022	Amp-dependent synthetase and ligase
BHG40_RS13435	COG0295	cytidine deaminase activity
BHG40_RS13440	COG1346	cytolysis
BHG40_RS13445	COG1380	Effector of murein hydrolase LrgA
BHG40_RS13455	COG3345	alpha-galactosidase
BHG40_RS13465	COG2925	Exonuclease
BHG40_RS13480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BHG40_RS13485	COG0436	Aminotransferase
BHG40_RS13490	COG0583	DNA-binding transcription factor activity
BHG40_RS13495	COG2160	L-arabinose isomerase activity
BHG40_RS13505	COG1069	ribulokinase activity
BHG40_RS13510	COG1879	ABC-type sugar transport system periplasmic component
BHG40_RS13520	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHG40_RS13530	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BHG40_RS13550	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHG40_RS13555	COG1609	Transcriptional regulator
BHG40_RS13565	COG4580	involved in the transport of maltose and maltodextrins
BHG40_RS13630	COG3833	ABC-type maltose transport systems, permease component
BHG40_RS13635	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BHG40_RS13655	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BHG40_RS13660	COG0254	rRNA binding
BHG40_RS13675	COG1451	nucleotide metabolic process
BHG40_RS13690	COG3069	C4-dicarboxylate transmembrane transporter activity
BHG40_RS13705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_RS13730	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
BHG40_RS13735	COG1053	succinate dehydrogenase
BHG40_RS13745	COG0567	Dehydrogenase, E1 component
BHG40_RS13750	COG0508	dehydrogenase complex catalyzes the overall conversion of
BHG40_RS13755	COG0045	succinate-CoA ligase (ADP-forming) activity
BHG40_RS13760	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BHG40_RS13765	COG2983	Belongs to the UPF0260 family
BHG40_RS13770	COG1882	Formate acetyltransferase
BHG40_RS13775	COG2116	formate transmembrane transporter activity
BHG40_RS13780	COG1944	ATP diphosphatase activity
BHG40_RS13785	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BHG40_RS13805	COG2910	NAD(P)H-binding
BHG40_RS13810	COG0583	DNA-binding transcription factor activity
BHG40_RS13820	COG3708	Transcriptional regulator
BHG40_RS13820	COG2207	Transcriptional regulator
BHG40_RS13825	COG4774	siderophore transport
BHG40_RS13835	COG0583	DNA-binding transcription factor activity
BHG40_RS13840	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BHG40_RS13870	COG3046	protein related to deoxyribodipyrimidine photolyase
BHG40_RS13880	COG3033	Beta-eliminating lyase
BHG40_RS13895	COG3088	subunit of a heme lyase
BHG40_RS13895	COG4235	cytochrome complex assembly
BHG40_RS13910	COG3301	Polysulphide reductase, NrfD
BHG40_RS13915	COG0437	4 iron, 4 sulfur cluster binding
BHG40_RS13920	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BHG40_RS13930	COG0247	lactate metabolic process
BHG40_RS13935	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BHG40_RS13940	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHG40_RS13945	COG3012	SEC-C Motif Domain Protein
BHG40_RS13950	COG0840	transmembrane signaling receptor activity
BHG40_RS13955	COG1846	Transcriptional regulator
BHG40_RS13955	COG1940	carbohydrate kinase activity
BHG40_RS13960	COG3290	protein histidine kinase activity
BHG40_RS13965	COG4565	transcriptional regulatory protein
BHG40_RS13995	COG5433	transposase activity
BHG40_RS14005	COG2985	domain, Protein
BHG40_RS14005	COG0569	domain protein
BHG40_RS14020	COG0556	nucleotide-excision repair
BHG40_RS14030	COG0586	Pfam SNARE associated Golgi protein
BHG40_RS14035	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BHG40_RS14040	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BHG40_RS14045	COG2186	Transcriptional regulator
BHG40_RS14060	COG2766	serine protein kinase
BHG40_RS14065	COG0514	ATP-dependent DNA helicase (RecQ)
BHG40_RS14070	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
BHG40_RS14075	COG0814	amino acid
BHG40_RS14085	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BHG40_RS14110	COG5433	transposase activity
BHG40_RS14155	COG0058	SHG alpha-glucan phosphorylase activity
BHG40_RS14160	COG0471	metal ion transport
BHG40_RS14165	COG3118	belongs to the thioredoxin family
BHG40_RS14180	COG1132	(ABC) transporter
BHG40_RS14190	COG2501	S4 domain
BHG40_RS14200	COG3243	poly(R)-hydroxyalkanoic acid synthase
BHG40_RS14220	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BHG40_RS14225	COG2329	Antibiotic biosynthesis monooxygenase
BHG40_RS14260	COG1742	UPF0060 membrane protein
BHG40_RS14275	COG0513	Belongs to the DEAD box helicase family
BHG40_RS14280	COG0386	Belongs to the glutathione peroxidase family
BHG40_RS14290	COG1181	Belongs to the D-alanine--D-alanine ligase family
BHG40_RS14300	COG3148	PFAM DTW domain containing protein
BHG40_RS14305	COG0730	response to heat
BHG40_RS14310	COG0583	DNA-binding transcription factor activity
BHG40_RS14325	COG3593	DNA synthesis involved in DNA repair
BHG40_RS14380	COG1011	Hydrolase
BHG40_RS14425	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BHG40_RS14435	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BHG40_RS14445	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
BHG40_RS14450	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BHG40_RS14455	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BHG40_RS14480	COG0242	peptide deformylase activity
BHG40_RS14525	COG4681	YaeQ
BHG40_RS14545	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_RS14565	COG3134	Outer membrane lipoprotein
BHG40_RS14595	COG0583	DNA-binding transcription factor activity
BHG40_RS14600	COG2723	6-phospho-beta-galactosidase activity
BHG40_RS14610	COG0583	DNA-binding transcription factor activity
BHG40_RS14615	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BHG40_RS14620	COG0673	inositol 2-dehydrogenase activity
BHG40_RS14625	COG0583	DNA-binding transcription factor activity
BHG40_RS14635	COG1560	Kdo2-lipid A biosynthetic process
BHG40_RS14665	COG0417	DNA replication proofreading
BHG40_RS14700	COG0534	Mate efflux family protein
BHG40_RS14710	COG0307	riboflavin synthase, alpha
BHG40_RS14725	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BHG40_RS14730	COG0697	spore germination
BHG40_RS14735	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BHG40_RS14780	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BHG40_RS14785	COG3099	Belongs to the UPF0263 family
BHG40_RS14790	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BHG40_RS14795	COG2894	cell division
BHG40_RS14800	COG0850	regulation of cytokinetic process
BHG40_RS14805	COG3100	YcgL domain-containing protein
BHG40_RS14810	COG2951	lytic endotransglycosylase activity
BHG40_RS14815	COG1760	l-serine dehydratase
BHG40_RS14825	COG1760	l-serine dehydratase
BHG40_RS14830	COG3123	guanosine phosphorylase activity
BHG40_RS14850	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
BHG40_RS14855	COG2067	long-chain fatty acid transport protein
BHG40_RS14860	COG2067	long-chain fatty acid transport protein
BHG40_RS14900	COG0714	Associated with various cellular activities
BHG40_RS14905	COG0183	Belongs to the thiolase family
BHG40_RS14910	COG1024	Enoyl-CoA hydratase
BHG40_RS14910	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHG40_RS14915	COG2824	Alkylphosphonate utilization operon protein PhnA
BHG40_RS14965	COG3706	GGDEF domain
BHG40_RS14970	COG2840	Smr protein MutS2
BHG40_RS14975	COG2890	protein-(glutamine-N5) methyltransferase activity
BHG40_RS14980	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BHG40_RS14990	COG0513	Belongs to the DEAD box helicase family
BHG40_RS14995	COG5654	RES domain protein
BHG40_RS15005	COG0814	amino acid
BHG40_RS15010	COG1609	Transcriptional regulator
BHG40_RS15015	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS15015	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS15020	COG1105	Belongs to the carbohydrate kinase PfkB family
BHG40_RS15025	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_RS15025	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
BHG40_RS15025	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BHG40_RS15030	COG3313	Fe-S protein
BHG40_RS15035	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BHG40_RS15040	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BHG40_RS15045	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHG40_RS15050	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BHG40_RS15060	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BHG40_RS15080	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BHG40_RS15085	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BHG40_RS15090	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BHG40_RS15095	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BHG40_RS15100	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BHG40_RS15105	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_RS15105	COG0072	phenylalanine-tRNA ligase activity
BHG40_RS15110	COG0776	regulation of translation
BHG40_RS15150	COG1609	Transcriptional regulator
BHG40_RS15155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_RS15160	COG1879	ABC-type sugar transport system periplasmic component
BHG40_RS15165	COG1172	Belongs to the binding-protein-dependent transport system permease family
BHG40_RS15175	COG1869	D-ribose catabolic process
BHG40_RS15195	COG0037	tRNA processing
BHG40_RS15200	COG0589	response to stress
BHG40_RS15205	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BHG40_RS15220	COG2217	Heavy metal translocating P-type atpase
BHG40_RS15230	COG2010	Cytochrome c
BHG40_RS15245	COG3278	Belongs to the heme-copper respiratory oxidase family
BHG40_RS15255	COG1956	GAF domain-containing protein
BHG40_RS15260	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
BHG40_RS15270	COG0308	aminopeptidase N
BHG40_RS15285	COG5433	transposase activity
BHG40_RS15295	COG0167	dihydroorotate dehydrogenase activity
BHG40_RS15310	COG0116	Belongs to the methyltransferase superfamily
BHG40_RS15310	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHG40_RS15320	COG0488	(ABC) transporter
BHG40_RS15335	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHG40_RS15340	COG1067	ATP-dependent peptidase activity
BHG40_RS15440	COG2003	Belongs to the UPF0758 family
BHG40_RS15475	COG0741	lytic transglycosylase activity
BHG40_RS15670	COG5433	transposase activity
BHG40_RS15735	COG3620	sequence-specific DNA binding
BHG40_RS15765	COG4221	oxidoreductase activity
BHG40_RS15810	COG0372	Belongs to the citrate synthase family
BHG40_RS15815	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BHG40_RS15825	COG2995	paraquat-inducible protein a
BHG40_RS15835	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BHG40_RS15835	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BHG40_RS15850	COG0084	hydrolase, TatD family'
BHG40_RS15855	COG0470	DNA polymerase III
BHG40_RS15860	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BHG40_RS15865	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BHG40_RS15870	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BHG40_RS15875	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_RS15880	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHG40_RS15885	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS15895	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHG40_RS15900	COG0416	fatty acid biosynthetic process
BHG40_RS15905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BHG40_RS15910	COG1399	metal-binding, possibly nucleic acid-binding protein
BHG40_RS15920	COG0546	phosphoglycolate phosphatase activity
BHG40_RS15930	COG1530	ribonuclease E activity
BHG40_RS15935	COG0306	phosphate transporter
BHG40_RS15940	COG0717	Belongs to the dCTP deaminase family
BHG40_RS15945	COG0572	uridine kinase
BHG40_RS15950	COG0489	protein tyrosine kinase activity
BHG40_RS15955	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_RS15955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BHG40_RS15960	COG0625	glutathione transferase activity
BHG40_RS15965	COG1254	Belongs to the acylphosphatase family
BHG40_RS15975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BHG40_RS15990	COG0709	Synthesizes selenophosphate from selenide and ATP
BHG40_RS15995	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BHG40_RS16000	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHG40_RS16005	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BHG40_RS16015	COG1643	Atp-dependent helicase
BHG40_RS16020	COG0517	IMP dehydrogenase activity
BHG40_RS16020	COG0617	tRNA 3'-terminal CCA addition
BHG40_RS16020	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BHG40_RS16025	COG2197	response regulator
BHG40_RS16030	COG3314	Sporulation integral membrane protein YlbJ
BHG40_RS16035	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BHG40_RS16040	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BHG40_RS16045	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BHG40_RS16050	COG2832	Protein of unknown function (DUF454)
BHG40_RS16055	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BHG40_RS16075	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_RS16080	COG2267	carboxylic ester hydrolase activity
BHG40_RS16090	COG1214	PFAM Peptidase M22, glycoprotease
BHG40_RS16095	COG1199	ATP-dependent helicase activity
BHG40_RS16105	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BHG40_RS16110	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BHG40_RS16115	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BHG40_RS16120	COG0131	Imidazoleglycerol-phosphate dehydratase
BHG40_RS16120	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BHG40_RS16125	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BHG40_RS16130	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BHG40_RS16135	COG3437	response regulator, receiver
BHG40_RS16140	COG2199	diguanylate cyclase activity
BHG40_RS16145	COG2198	Histidine kinase
BHG40_RS16145	COG2205	protein histidine kinase activity
BHG40_RS16145	COG0784	Response regulator, receiver
BHG40_RS16150	COG0107	imidazoleglycerol-phosphate synthase activity
BHG40_RS16155	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BHG40_RS16155	COG0140	phosphoribosyl-ATP diphosphatase activity
BHG40_RS16165	COG2378	regulation of single-species biofilm formation
BHG40_RS16200	COG0730	response to heat
BHG40_RS16210	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS16220	COG1024	Enoyl-CoA hydratase
BHG40_RS16225	COG1024	Enoyl-CoA hydratase
BHG40_RS16230	COG1960	acyl-CoA dehydrogenase activity
BHG40_RS16255	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BHG40_RS16260	COG1024	Enoyl-CoA hydratase
BHG40_RS16290	COG1584	GPR1 FUN34 yaaH family protein
BHG40_RS16300	COG0456	acetyltransferase
BHG40_RS16310	COG1250	3-hydroxyacyl-CoA dehydrogenase
BHG40_RS16310	COG1024	Enoyl-CoA hydratase
BHG40_RS16325	COG3162	membrane
BHG40_RS16330	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BHG40_RS16335	COG0488	(ABC) transporter
BHG40_RS16340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHG40_RS16345	COG0776	regulation of translation
BHG40_RS16350	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BHG40_RS16355	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BHG40_RS16360	COG0740	serine-type endopeptidase activity
BHG40_RS16365	COG0544	peptidyl-prolyl cis-trans isomerase activity
BHG40_RS16380	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BHG40_RS16385	COG4591	ABC-type transport system involved in lipoprotein release permease component
BHG40_RS16390	COG1136	(ABC) transporter
BHG40_RS16395	COG4591	ABC-type transport system involved in lipoprotein release permease component
BHG40_RS16405	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BHG40_RS16410	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
BHG40_RS16415	COG4166	transmembrane transport
BHG40_RS16420	COG0697	spore germination
BHG40_RS16430	COG2062	phosphohistidine phosphatase, SixA
BHG40_RS16490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BHG40_RS16490	COG0519	Catalyzes the synthesis of GMP from XMP
BHG40_RS16495	COG0516	GMP reductase activity
BHG40_RS16495	COG0517	IMP dehydrogenase activity
BHG40_RS16520	COG5433	transposase activity
BHG40_RS16540	COG1570	exodeoxyribonuclease VII activity
BHG40_RS16555	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_RS16560	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BHG40_RS16565	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BHG40_RS16605	COG4771	TonB-dependent receptor
BHG40_RS16610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_RS16615	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BHG40_RS16620	COG1120	ATPase activity
BHG40_RS16625	COG2977	Belongs to the P-Pant transferase superfamily
BHG40_RS16630	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHG40_RS16635	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_RS16635	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHG40_RS16635	COG3321	synthase
BHG40_RS16635	COG0300	oxidoreductase activity
BHG40_RS16635	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS16645	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS16650	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHG40_RS16655	COG3433	isochorismatase activity
BHG40_RS16655	COG1535	isochorismatase
BHG40_RS16660	COG1021	2,3-dihydroxybenzoate-AMP ligase
BHG40_RS16715	COG0840	transmembrane signaling receptor activity
BHG40_RS16720	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_RS16725	COG3788	relative of glutathione S-transferase, MAPEG superfamily
BHG40_RS16730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BHG40_RS16735	COG0563	adenylate kinase activity
BHG40_RS16745	COG0326	Molecular chaperone. Has ATPase activity
BHG40_RS16750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BHG40_RS16800	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHG40_RS16805	COG0651	ATP synthesis coupled electron transport
BHG40_RS16810	COG0650	Formate hydrogenlyase subunit 4
BHG40_RS16815	COG3261	NADH dehydrogenase
BHG40_RS16815	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BHG40_RS16820	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_RS16825	COG3260	NADH ubiquinone oxidoreductase 20
BHG40_RS16840	COG1921	L-seryl-tRNASec selenium transferase activity
BHG40_RS16850	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BHG40_RS16855	COG0298	carbon dioxide binding
BHG40_RS16865	COG0309	Hydrogenase expression formation protein (HypE)
BHG40_RS16870	COG0375	protein maturation
BHG40_RS16875	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BHG40_RS16890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_RS16895	COG0601	transmembrane transport
BHG40_RS16905	COG1773	rubredoxin
BHG40_RS16910	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BHG40_RS16915	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BHG40_RS16920	COG5557	Pfam Polysulphide reductase, NrfD
BHG40_RS16925	COG0437	4 iron, 4 sulfur cluster binding
BHG40_RS16950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHG40_RS16975	COG1435	thymidine kinase activity
BHG40_RS16980	COG1757	Na H antiporter
BHG40_RS16995	COG2916	Histone family protein nucleoid-structuring protein H-NS
BHG40_RS17000	COG2096	Adenosyltransferase
BHG40_RS17005	COG3530	Putative quorum-sensing-regulated virulence factor
BHG40_RS17010	COG0602	queuosine metabolic process
BHG40_RS17015	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BHG40_RS17030	COG0284	orotidine-5'-phosphate decarboxylase activity
BHG40_RS17035	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
BHG40_RS17045	COG0776	regulation of translation
BHG40_RS17050	COG0539	negative regulation of cytoplasmic translation
BHG40_RS17055	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BHG40_RS17060	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BHG40_RS17075	COG2814	Major facilitator Superfamily
BHG40_RS17095	COG3300	MHYT domain
BHG40_RS17095	COG5001	Diguanylate cyclase
BHG40_RS17110	COG0583	DNA-binding transcription factor activity
BHG40_RS17140	COG4989	oxidoreductase activity
BHG40_RS17145	COG0724	RNA recognition motif
BHG40_RS17155	COG1126	abc transporter atp-binding protein
BHG40_RS17160	COG0765	amino acid transport
BHG40_RS17165	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS17170	COG4597	amino acid ABC transporter
BHG40_RS17185	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BHG40_RS17205	COG1360	Flagellar Motor Protein
BHG40_RS17210	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_RS17220	COG0649	NAD binding
BHG40_RS17220	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_RS17235	COG1034	ATP synthesis coupled electron transport
BHG40_RS17240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BHG40_RS17245	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_RS17250	COG0839	Belongs to the complex I subunit 6 family
BHG40_RS17255	COG0713	ATP synthesis coupled electron transport
BHG40_RS17265	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BHG40_RS17270	COG1007	ATP synthesis coupled electron transport
BHG40_RS17285	COG5433	transposase activity
BHG40_RS17305	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_RS17310	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_RS17345	COG0537	adenosine 5'-monophosphoramidase activity
BHG40_RS17360	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BHG40_RS17375	COG1301	dicarboxylic acid transport
BHG40_RS17385	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BHG40_RS17390	COG0861	Integral membrane protein TerC family
BHG40_RS17405	COG0444	Belongs to the ABC transporter superfamily
BHG40_RS17410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_RS17415	COG0601	transmembrane transport
BHG40_RS17425	COG2095	MarC family integral membrane protein
BHG40_RS17435	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_RS17435	COG1454	alcohol dehydrogenase
BHG40_RS17455	COG3275	phosphorelay sensor kinase activity
BHG40_RS17460	COG3279	Response regulator of the LytR AlgR family
BHG40_RS17465	COG1966	Carbon starvation protein
BHG40_RS17475	COG1566	PFAM secretion protein HlyD family protein
BHG40_RS17480	COG1061	Type III restriction enzyme res subunit
BHG40_RS17485	COG2027	D-alanyl-D-alanine carboxypeptidase
BHG40_RS17490	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BHG40_RS17500	COG0436	Aminotransferase
BHG40_RS17505	COG1288	antiporter activity
BHG40_RS17510	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BHG40_RS17580	COG1242	4 iron, 4 sulfur cluster binding
BHG40_RS17605	COG5433	transposase activity
BHG40_RS17620	COG2354	Protein conserved in bacteria
BHG40_RS17630	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BHG40_RS17630	COG0047	phosphoribosylformylglycinamidine synthase activity
BHG40_RS17635	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BHG40_RS17640	COG1645	bacterial-type flagellum-dependent swarming motility
BHG40_RS17645	COG1160	GTP binding
BHG40_RS17650	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BHG40_RS17655	COG2976	Protein conserved in bacteria
BHG40_RS17660	COG0124	histidyl-tRNA synthetase
BHG40_RS17665	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BHG40_RS17670	COG1426	Protein conserved in bacteria
BHG40_RS17680	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BHG40_RS17685	COG0105	UTP biosynthetic process
BHG40_RS17690	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BHG40_RS17700	COG0633	Ferredoxin
BHG40_RS17705	COG0443	Heat shock 70 kDa protein
BHG40_RS17710	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BHG40_RS17720	COG0822	iron-sulfur transferase activity
BHG40_RS17725	COG1104	cysteine desulfurase activity
BHG40_RS17730	COG1959	2 iron, 2 sulfur cluster binding
BHG40_RS17745	COG3154	lipid carrier protein
BHG40_RS17750	COG0826	peptidase U32
BHG40_RS17755	COG0826	peptidase U32
BHG40_RS17765	COG2897	thiosulfate sulfurtransferase activity
BHG40_RS17770	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_RS17775	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BHG40_RS17780	COG1862	Preprotein translocase
BHG40_RS17785	COG0343	queuine tRNA-ribosyltransferase activity
BHG40_RS17790	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BHG40_RS17795	COG0517	IMP dehydrogenase activity
BHG40_RS17805	COG3634	alkyl hydroperoxide reductase activity
BHG40_RS17820	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BHG40_RS17820	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BHG40_RS17825	COG0509	glycine decarboxylation via glycine cleavage system
BHG40_RS17830	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BHG40_RS17835	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHG40_RS17840	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHG40_RS17860	COG0243	molybdopterin cofactor binding
BHG40_RS17865	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BHG40_RS17875	COG2814	Major facilitator Superfamily
BHG40_RS17880	COG0444	Belongs to the ABC transporter superfamily
BHG40_RS17885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_RS17890	COG0601	transmembrane transport
BHG40_RS17900	COG0625	glutathione transferase activity
BHG40_RS17910	COG0483	inositol monophosphate 1-phosphatase activity
BHG40_RS17930	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BHG40_RS17940	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BHG40_RS17970	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BHG40_RS17985	COG0301	tRNA thio-modification
BHG40_RS17985	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BHG40_RS17995	COG4953	penicillin-binding protein 1C
BHG40_RS18000	COG2373	Large extracellular alpha-helical protein
BHG40_RS18005	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_RS18015	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BHG40_RS18050	COG2431	L-lysine efflux transmembrane transporter activity
BHG40_RS18065	COG1393	Belongs to the ArsC family
BHG40_RS18075	COG4783	chaperone-mediated protein folding
BHG40_RS18080	COG0425	Belongs to the sulfur carrier protein TusA family
BHG40_RS18085	COG0628	permease
BHG40_RS18100	COG3842	ATPase activity
BHG40_RS18105	COG3833	ABC-type maltose transport systems, permease component
BHG40_RS18115	COG2182	Extracellular solute-binding protein
BHG40_RS18120	COG3081	Nucleoid-associated protein
BHG40_RS18125	COG3082	Protein of unknown function (DUF1414)
BHG40_RS18130	COG3083	sulfuric ester hydrolase activity
BHG40_RS18150	COG1770	oligopeptidase
BHG40_RS18170	COG4574	serine-type endopeptidase inhibitor activity
BHG40_RS18175	COG3085	chromosome segregation
BHG40_RS18180	COG0583	DNA-binding transcription factor activity
BHG40_RS18185	COG0287	Prephenate dehydrogenase
BHG40_RS18185	COG1605	Chorismate mutase
BHG40_RS18190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BHG40_RS18195	COG0584	glycerophosphoryl diester phosphodiesterase
BHG40_RS18200	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BHG40_RS18210	COG1349	DNA-binding transcription factor activity
BHG40_RS18215	COG2271	Major facilitator Superfamily
BHG40_RS18220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHG40_RS18225	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BHG40_RS18230	COG0583	DNA-binding transcription factor activity
BHG40_RS18255	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
BHG40_RS18260	COG0656	L-ascorbic acid biosynthetic process
BHG40_RS18265	COG2814	Major facilitator Superfamily
BHG40_RS18295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BHG40_RS18300	COG2979	Protein of unknown function (DUF533)
BHG40_RS18320	COG0583	DNA-binding transcription factor activity
BHG40_RS18330	COG2807	transmembrane transport
BHG40_RS18335	COG1187	pseudouridine synthase activity
BHG40_RS18340	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BHG40_RS18350	COG0346	lactoylglutathione lyase activity
BHG40_RS18365	COG1166	arginine decarboxylase activity
BHG40_RS18375	COG2195	Cleaves the N-terminal amino acid of tripeptides
BHG40_RS18400	COG2353	YceI-like domain
BHG40_RS18405	COG0583	DNA-binding transcription factor activity
BHG40_RS18415	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BHG40_RS18420	COG0840	transmembrane signaling receptor activity
BHG40_RS18425	COG0302	gtp cyclohydrolase
BHG40_RS18435	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BHG40_RS18465	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BHG40_RS18480	COG0314	molybdopterin synthase activity
BHG40_RS18485	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BHG40_RS18490	COG0315	cyclic pyranopterin monophosphate synthase activity
BHG40_RS18495	COG0521	Mo-molybdopterin cofactor biosynthetic process
BHG40_RS18500	COG3005	denitrification pathway
BHG40_RS18510	COG0348	domain, Protein
BHG40_RS18515	COG0437	4 iron, 4 sulfur cluster binding
BHG40_RS18520	COG0243	molybdopterin cofactor binding
BHG40_RS18530	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BHG40_RS18535	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BHG40_RS18540	COG3850	Histidine kinase
BHG40_RS18545	COG2197	response regulator
BHG40_RS18575	COG0121	glutamine amidotransferase
BHG40_RS18580	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BHG40_RS18585	COG1960	acyl-CoA dehydrogenase activity
BHG40_RS18590	COG0784	Response regulator, receiver
BHG40_RS18590	COG3437	response regulator, receiver
BHG40_RS18600	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BHG40_RS18605	COG0328	RNA-DNA hybrid ribonuclease activity
BHG40_RS18610	COG2226	methyltransferase
BHG40_RS18615	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BHG40_RS18620	COG1388	LysM domain
BHG40_RS18620	COG0741	lytic transglycosylase activity
BHG40_RS18625	COG3021	interspecies interaction between organisms
BHG40_RS18635	COG1607	acyl-coa hydrolase
BHG40_RS18660	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BHG40_RS18675	COG2911	Protein conserved in bacteria
BHG40_RS18680	COG0729	surface antigen
BHG40_RS18695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BHG40_RS18700	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BHG40_RS18710	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BHG40_RS18715	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BHG40_RS18720	COG4134	Bacterial extracellular solute-binding protein
BHG40_RS18725	COG4135	transport system, permease component
BHG40_RS18730	COG4136	ATPase activity
BHG40_RS18735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BHG40_RS18740	COG2951	lytic endotransglycosylase activity
BHG40_RS18745	COG1846	Transcriptional regulator
BHG40_RS18755	COG0033	Phosphoglucomutase
BHG40_RS18760	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
BHG40_RS18765	COG0596	Alpha beta hydrolase
BHG40_RS18780	COG0716	FMN binding
BHG40_RS18790	COG0735	belongs to the Fur family
BHG40_RS18795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BHG40_RS18815	COG0363	glucosamine-6-phosphate deaminase activity
BHG40_RS18820	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BHG40_RS18825	COG1846	Transcriptional regulator
BHG40_RS18825	COG1940	carbohydrate kinase activity
BHG40_RS18855	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BHG40_RS18890	COG0217	transcriptional regulatory protein
BHG40_RS18895	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BHG40_RS18915	COG4106	trans-aconitate 2-methyltransferase activity
BHG40_RS18920	COG0500	methyltransferase
BHG40_RS18940	COG0450	alkyl hydroperoxide reductase
BHG40_RS18950	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BHG40_RS18975	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BHG40_RS18985	COG1684	flagellar biosynthetic protein fliR
BHG40_RS19040	COG1342	Belongs to the UPF0251 family
BHG40_RS19060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BHG40_RS19085	COG1737	Transcriptional regulator
BHG40_RS19090	COG0469	pyruvate kinase activity
BHG40_RS19100	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHG40_RS19105	COG1960	acyl-CoA dehydrogenase activity
BHG40_RS19155	COG1376	ErfK ybiS ycfS ynhG family protein
BHG40_RS19155	COG1388	LysM domain
BHG40_RS19170	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
BHG40_RS19175	COG0791	NLP P60 protein
BHG40_RS19180	COG2091	lysine biosynthetic process via aminoadipic acid
BHG40_RS19185	COG3118	belongs to the thioredoxin family
BHG40_RS19195	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BHG40_RS19200	COG0788	formyltetrahydrofolate deformylase activity
BHG40_RS19230	COG0366	Alpha amylase catalytic
BHG40_RS19240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BHG40_RS19245	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BHG40_RS19260	COG5433	transposase activity
BHG40_RS19275	COG1032	radical SAM domain protein
BHG40_RS19285	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BHG40_RS19290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BHG40_RS19295	COG3706	GGDEF domain
BHG40_RS19300	COG1752	Esterase of the alpha-beta hydrolase superfamily
BHG40_RS19305	COG0733	neurotransmitter:sodium symporter activity
BHG40_RS19340	COG0281	malic enzyme
BHG40_RS19345	COG2207	Transcriptional regulator
BHG40_RS19350	COG0534	Mate efflux family protein
BHG40_RS19365	COG2233	PERMEase
BHG40_RS19370	COG0095	Lipoate-protein ligase
BHG40_RS19375	COG1115	amino acid carrier protein
BHG40_RS19380	COG0019	diaminopimelate decarboxylase activity
BHG40_RS19420	COG1131	(ABC) transporter
BHG40_RS19425	COG0545	Peptidyl-prolyl cis-trans isomerase
BHG40_RS19430	COG3142	Participates in the control of copper homeostasis
BHG40_RS19435	COG1940	carbohydrate kinase activity
BHG40_RS19455	COG5002	protein histidine kinase activity
BHG40_RS19460	COG0745	RESPONSE REGULATOR receiver
BHG40_RS19465	COG0346	lactoylglutathione lyase activity
BHG40_RS19470	COG3706	GGDEF domain
BHG40_RS19475	COG3284	Transcriptional regulator
BHG40_RS19485	COG1942	4-Oxalocrotonate Tautomerase
BHG40_RS19490	COG2267	carboxylic ester hydrolase activity
BHG40_RS19510	COG0697	spore germination
BHG40_RS19520	COG0667	Aldo Keto reductase
BHG40_RS19535	COG3290	protein histidine kinase activity
BHG40_RS19540	COG0281	malic enzyme
BHG40_RS19560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BHG40_RS19570	COG0281	malic enzyme
BHG40_RS19585	COG0437	4 iron, 4 sulfur cluster binding
BHG40_RS19590	COG3383	formate dehydrogenase (NAD+) activity
BHG40_RS19620	COG5433	transposase activity
BHG40_RS19635	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BHG40_RS19645	COG3852	Histidine kinase
BHG40_RS19660	COG4662	Binding-protein-dependent transport system inner membrane component
BHG40_RS19670	COG0746	molybdenum cofactor guanylyltransferase activity
BHG40_RS19675	COG0303	'Molybdopterin
BHG40_RS19680	COG1289	transmembrane transporter activity
BHG40_RS19685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BHG40_RS19735	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BHG40_RS19740	COG0444	Belongs to the ABC transporter superfamily
BHG40_RS19745	COG4608	Belongs to the ABC transporter superfamily
BHG40_RS19755	COG2971	BadF BadG BcrA BcrD
BHG40_RS19765	COG0840	transmembrane signaling receptor activity
BHG40_RS19780	COG3724	N-succinylarginine dihydrolase activity
BHG40_RS19785	COG0616	signal peptide processing
BHG40_RS19790	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS19795	COG0583	DNA-binding transcription factor activity
BHG40_RS19805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BHG40_RS19815	COG0583	DNA-binding transcription factor activity
BHG40_RS19820	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BHG40_RS19825	COG1881	PFAM PEBP family protein
BHG40_RS19835	COG0366	Alpha amylase catalytic
BHG40_RS19875	COG0037	tRNA processing
BHG40_RS19880	COG3590	peptidase
BHG40_RS19890	COG0488	(ABC) transporter
BHG40_RS19900	COG0531	amino acid
BHG40_RS19905	COG0814	amino acid
BHG40_RS19920	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BHG40_RS19925	COG1982	Orn Lys Arg decarboxylase major
BHG40_RS19930	COG0531	amino acid
BHG40_RS19935	COG3710	Transcriptional regulator
BHG40_RS19940	COG0825	malonyl-CoA metabolic process
BHG40_RS19950	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BHG40_RS19955	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_RS19960	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_RS19965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BHG40_RS19970	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BHG40_RS19985	COG0750	zinc metalloprotease
BHG40_RS19990	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BHG40_RS19995	COG0575	Belongs to the CDS family
BHG40_RS20000	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BHG40_RS20005	COG0233	cytoplasmic translational termination
BHG40_RS20010	COG0528	UMP kinase activity
BHG40_RS20015	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BHG40_RS20020	COG0052	Belongs to the universal ribosomal protein uS2 family
BHG40_RS20025	COG0024	Methionine aminopeptidase
BHG40_RS20035	COG2171	N-acyltransferase activity
BHG40_RS20045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_RS20045	COG1263	PTS System
BHG40_RS20055	COG4580	involved in the transport of maltose and maltodextrins
BHG40_RS20060	COG5433	transposase activity
BHG40_RS20070	COG0564	pseudouridine synthase activity
BHG40_RS20075	COG3098	single-species biofilm formation
BHG40_RS20100	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
BHG40_RS20110	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BHG40_RS20110	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BHG40_RS20125	COG1611	Belongs to the LOG family
BHG40_RS20130	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BHG40_RS20135	COG0473	3-isopropylmalate dehydrogenase activity
BHG40_RS20145	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BHG40_RS20150	COG2363	Small membrane protein
BHG40_RS20160	COG0583	DNA-binding transcription factor activity
BHG40_RS20165	COG0840	transmembrane signaling receptor activity
BHG40_RS20170	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BHG40_RS20185	COG1477	protein flavinylation
BHG40_RS20190	COG2871	sodium ion transport
BHG40_RS20195	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_RS20200	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_RS20205	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_RS20210	COG1805	sodium ion transport
BHG40_RS20215	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
BHG40_RS20220	COG0271	Belongs to the BolA IbaG family
BHG40_RS20225	COG2813	Specifically methylates the guanine in position
BHG40_RS20235	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BHG40_RS20245	COG2211	Major facilitator Superfamily
BHG40_RS20250	COG3248	Nucleoside-binding outer membrane protein
BHG40_RS20255	COG1666	GTP binding
BHG40_RS20260	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BHG40_RS20265	COG0693	protein deglycase activity
BHG40_RS20285	COG3459	Glycosyltransferase 36 associated
BHG40_RS20300	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BHG40_RS20300	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BHG40_RS20305	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BHG40_RS20315	COG1151	hydroxylamine reductase activity
BHG40_RS20320	COG0783	Belongs to the Dps family
BHG40_RS20345	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BHG40_RS20360	COG0300	oxidoreductase activity
BHG40_RS20370	COG0415	Belongs to the DNA photolyase family
BHG40_RS20375	COG0789	Transcriptional regulator
BHG40_RS20380	COG3272	Protein of unknown function (DUF1722)
BHG40_RS20410	COG1605	Chorismate mutase
BHG40_RS20410	COG0077	Prephenate dehydratase
BHG40_RS20435	COG2133	pyrroloquinoline quinone binding
BHG40_RS20460	COG0300	oxidoreductase activity
BHG40_RS20485	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BHG40_RS20500	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BHG40_RS20510	COG3813	Protein conserved in bacteria
BHG40_RS20525	COG1280	lysine exporter protein (LysE YggA)
BHG40_RS20535	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BHG40_RS20545	COG0745	RESPONSE REGULATOR receiver
BHG40_RS20565	COG0835	chemotaxis
BHG40_RS20570	COG0840	transmembrane signaling receptor activity
BHG40_RS20600	COG5433	transposase activity
BHG40_RS20615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BHG40_RS20620	COG1396	sequence-specific DNA binding
BHG40_RS20620	COG1917	Cupin 2, conserved barrel domain protein
BHG40_RS20635	COG0531	amino acid
BHG40_RS20645	COG0531	amino acid
BHG40_RS20650	COG1283	sodium-dependent phosphate transmembrane transporter activity
BHG40_RS20660	COG3384	dioxygenase
BHG40_RS20675	COG0813	purine-nucleoside phosphorylase activity
BHG40_RS20700	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BHG40_RS20705	COG0083	homoserine kinase activity
BHG40_RS20715	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BHG40_RS20720	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BHG40_RS20735	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BHG40_RS20745	COG0745	RESPONSE REGULATOR receiver
BHG40_RS20760	COG4988	ABC transporter
BHG40_RS20765	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
BHG40_RS20785	COG1720	tRNA m6t6A37 methyltransferase activity
BHG40_RS20805	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BHG40_RS20810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BHG40_RS20820	COG2190	(PTS) system
BHG40_RS20835	COG3038	cytochrome b561
BHG40_RS20845	COG5433	transposase activity
BHG40_RS20855	COG0419	ATPase involved in DNA repair
BHG40_RS20860	COG0420	3'-5' exonuclease activity
BHG40_RS20870	COG2974	May be involved in recombination
BHG40_RS20875	COG0405	Gamma-glutamyltransferase
BHG40_RS20880	COG4651	solute:proton antiporter activity
BHG40_RS20880	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHG40_RS20885	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BHG40_RS20885	COG4651	solute:proton antiporter activity
BHG40_RS20900	COG0469	pyruvate kinase activity
BHG40_RS20905	COG3264	Mechanosensitive ion channel
BHG40_RS20905	COG1196	nuclear chromosome segregation
BHG40_RS20910	COG0582	viral genome integration into host DNA
BHG40_RS20925	COG1846	Transcriptional regulator
BHG40_RS20930	COG1566	PFAM secretion protein HlyD family protein
BHG40_RS20955	COG0602	queuosine metabolic process
BHG40_RS20965	COG1328	CTP reductase activity
BHG40_RS20975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BHG40_RS20980	COG3115	cell septum assembly
BHG40_RS20985	COG1196	nuclear chromosome segregation
BHG40_RS20995	COG2860	membrane
BHG40_RS21010	COG2989	Protein conserved in bacteria
BHG40_RS21025	COG0463	Glycosyl transferase, family 2
BHG40_RS21045	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BHG40_RS21050	COG0739	heme binding
BHG40_RS21055	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BHG40_RS21075	COG5433	transposase activity
BHG40_RS21080	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BHG40_RS21090	COG3091	SprT-like family
BHG40_RS21100	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BHG40_RS21105	COG0189	ligase activity
BHG40_RS21125	COG1678	Uncharacterized ACR, COG1678
BHG40_RS21130	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BHG40_RS21150	COG0714	Associated with various cellular activities
BHG40_RS21165	COG1115	amino acid carrier protein
BHG40_RS21170	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BHG40_RS21185	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BHG40_RS21225	COG2912	Transglutaminase-like superfamily
BHG40_RS21235	COG2890	protein-(glutamine-N5) methyltransferase activity
BHG40_RS21240	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BHG40_RS21245	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BHG40_RS21250	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BHG40_RS21255	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BHG40_RS21265	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BHG40_RS21270	COG0737	Belongs to the 5'-nucleotidase family
BHG40_RS21275	COG0193	aminoacyl-tRNA hydrolase activity
BHG40_RS21280	COG0012	GTP binding
BHG40_RS21325	COG0471	metal ion transport
BHG40_RS21325	COG0490	domain, Protein
BHG40_RS21335	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
BHG40_RS21370	COG0443	Heat shock 70 kDa protein
BHG40_RS21385	COG0366	Alpha amylase catalytic
BHG40_RS21400	COG0488	(ABC) transporter
BHG40_RS21420	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHG40_RS21430	COG1012	belongs to the aldehyde dehydrogenase family
BHG40_RS21440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BHG40_RS21455	COG0180	Tryptophanyl-tRNA synthetase
BHG40_RS21460	COG0546	phosphoglycolate phosphatase activity
BHG40_RS21465	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BHG40_RS21470	COG0338	D12 class N6 adenine-specific DNA methyltransferase
BHG40_RS21480	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BHG40_RS21485	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BHG40_RS21515	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BHG40_RS21520	COG0583	DNA-binding transcription factor activity
BHG40_RS21525	COG0840	transmembrane signaling receptor activity
BHG40_RS21540	COG0583	DNA-binding transcription factor activity
BHG40_RS21555	COG0739	heme binding
BHG40_RS21585	COG0584	glycerophosphoryl diester phosphodiesterase
BHG40_RS21600	COG1053	succinate dehydrogenase
BHG40_RS21605	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BHG40_RS21610	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BHG40_RS21615	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
BHG40_RS21635	COG3214	Protein conserved in bacteria
BHG40_RS21675	COG0642	Histidine kinase
BHG40_RS21685	COG0516	GMP reductase activity
BHG40_RS21695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BHG40_RS21705	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BHG40_RS21725	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BHG40_RS21740	COG3706	GGDEF domain
BHG40_RS21750	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BHG40_RS21755	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BHG40_RS21760	COG1702	phosphate starvation-inducible protein PhoH
BHG40_RS21765	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BHG40_RS21770	COG4535	Mg2 and Co2 transporter CorC
BHG40_RS21775	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BHG40_RS21780	COG2888	peptidyl-tyrosine sulfation
BHG40_RS21785	COG0495	leucyl-tRNA aminoacylation
BHG40_RS21805	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BHG40_RS21810	COG0799	negative regulation of ribosome biogenesis
BHG40_RS21815	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BHG40_RS21820	COG0768	penicillin binding
BHG40_RS21825	COG0772	Belongs to the SEDS family
BHG40_RS21830	COG2951	lytic endotransglycosylase activity
BHG40_RS21835	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BHG40_RS21840	COG1686	Belongs to the peptidase S11 family
BHG40_RS21845	COG2921	Belongs to the UPF0250 family
BHG40_RS21850	COG0321	lipoyl(octanoyl) transferase activity
BHG40_RS21860	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BHG40_RS21875	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BHG40_RS21880	COG3545	Serine hydrolase
BHG40_RS21895	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BHG40_RS21905	COG1970	mechanosensitive ion channel activity
BHG40_RS21915	COG4974	Belongs to the 'phage' integrase family
BHG40_RS21930	COG0312	modulator of DNA gyrase
BHG40_RS21975	COG5433	transposase activity
BHG40_RS21990	COG1422	Protein of unknown function (DUF1090)
BHG40_RS21995	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BHG40_RS22000	COG3706	GGDEF domain
BHG40_RS22005	COG2211	Major facilitator Superfamily
BHG40_RS22010	COG1185	polyribonucleotide nucleotidyltransferase activity
BHG40_RS22015	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BHG40_RS22020	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BHG40_RS22025	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BHG40_RS22035	COG0195	Participates in both transcription termination and antitermination
BHG40_RS22040	COG0779	Required for maturation of 30S ribosomal subunits
BHG40_RS22055	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BHG40_RS22060	COG0149	triose-phosphate isomerase activity
BHG40_RS22065	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BHG40_RS22070	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BHG40_RS22080	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BHG40_RS22085	COG1534	Rna-binding protein
BHG40_RS22110	COG1360	Flagellar Motor Protein
BHG40_RS22115	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BHG40_RS22120	COG1722	exodeoxyribonuclease VII activity
BHG40_RS22125	COG0142	geranyltranstransferase activity
BHG40_RS22130	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BHG40_RS22140	COG0601	transmembrane transport
BHG40_RS22150	COG4172	Belongs to the ABC transporter superfamily
BHG40_RS22155	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BHG40_RS22160	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BHG40_RS22165	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BHG40_RS22170	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BHG40_RS22185	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHG40_RS22185	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BHG40_RS22190	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BHG40_RS22205	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BHG40_RS22225	COG3381	protein complex oligomerization
BHG40_RS22255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BHG40_RS22260	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BHG40_RS22265	COG0511	ligase activity, forming carbon-carbon bonds
BHG40_RS22270	COG0439	Biotin carboxylase
BHG40_RS22275	COG3924	membrane
BHG40_RS22280	COG4145	pantothenate transmembrane transporter activity
BHG40_RS22285	COG1263	PTS System
BHG40_RS22285	COG2190	(PTS) system
BHG40_RS22285	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BHG40_RS22290	COG0583	DNA-binding transcription factor activity
BHG40_RS22295	COG0604	alcohol dehydrogenase
BHG40_RS22300	COG2264	protein methyltransferase activity
BHG40_RS22305	COG0531	amino acid
BHG40_RS22310	COG4303	Ethanolamine ammonia lyase large subunit
BHG40_RS22315	COG4302	ethanolamine ammonia-lyase activity
BHG40_RS22335	COG0778	Nitroreductase
BHG40_RS22340	COG0446	pyridine nucleotide-disulphide oxidoreductase
BHG40_RS22340	COG1902	pentaerythritol trinitrate reductase activity
BHG40_RS22345	COG0616	signal peptide processing
BHG40_RS22365	COG3139	Protein of unknown function (DUF1315)
BHG40_RS22370	COG0252	asparaginase activity
BHG40_RS22375	COG0786	glutamate:sodium symporter activity
BHG40_RS22390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BHG40_RS22395	COG0384	phenazine biosynthesis protein PhzF
BHG40_RS22400	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BHG40_RS22405	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BHG40_RS22410	COG0175	sulfate reduction
BHG40_RS22415	COG2113	Glycine betaine
BHG40_RS22420	COG4176	ABC-type proline glycine betaine transport system permease component
BHG40_RS22425	COG4175	Glycine betaine
BHG40_RS22435	COG3610	response to peptide
BHG40_RS22440	COG2966	Psort location CytoplasmicMembrane, score
BHG40_RS22455	COG0521	Mo-molybdopterin cofactor biosynthetic process
BHG40_RS22465	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_RS22470	COG1028	Short-chain dehydrogenase reductase Sdr
BHG40_RS22480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BHG40_RS22505	COG2986	histidine ammonia-lyase
BHG40_RS22520	COG0318	PFAM AMP-dependent synthetase and ligase
BHG40_RS22530	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHG40_RS22535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BHG40_RS22580	COG1858	cytochrome C peroxidase
BHG40_RS22585	COG5433	transposase activity
BHG40_RS22595	COG2313	pseudouridylate synthase activity
BHG40_RS22600	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BHG40_RS22600	COG1522	sequence-specific DNA binding
BHG40_RS22630	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BHG40_RS22635	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BHG40_RS22645	COG1073	alpha beta
BHG40_RS22650	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BHG40_RS22655	COG4974	Belongs to the 'phage' integrase family
BHG40_RS22740	COG5002	protein histidine kinase activity
BHG40_RS22740	COG2176	DNA-directed DNA polymerase activity
BHG40_RS22785	COG4695	Portal protein
BHG40_RS22835	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BHG40_RS22840	COG4279	zinc finger
BHG40_RS22860	COG1192	Involved in chromosome partitioning
BHG40_RS22915	COG2003	Belongs to the UPF0758 family
BHG40_RS22965	COG3039	Transposase
BHG40_RS23115	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BHG40_RS23120	COG2361	Protein of unknown function DUF86
BHG40_RS23140	COG1192	Involved in chromosome partitioning
BHG40_RS23220	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BHG40_RS23250	COG2916	Histone family protein nucleoid-structuring protein H-NS
BHG40_RS23260	COG1192	Involved in chromosome partitioning
BHG40_RS23270	COG3328	transposase activity
BHG40_RS23300	COG1317	bacterial-type flagellum organization
BHG40_RS23395	COG0457	Tetratricopeptide repeat
BHG40_RS23465	COG4790	Type iii secretion
BHG40_RS23470	COG4794	Type iii secretion
BHG40_RS23475	COG4791	protein targeting
BHG40_RS23480	COG4792	protein secretion
BHG40_RS23535	COG1484	DNA-dependent DNA replication