locus-tag	class	description
G9H43_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G9H43_RS00010	COG0592	DNA-directed DNA polymerase activity
G9H43_RS00035	COG2378	regulation of single-species biofilm formation
G9H43_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
G9H43_RS00045	COG0071	Belongs to the small heat shock protein (HSP20) family
G9H43_RS00065	COG3977	Valine--pyruvate aminotransferase
G9H43_RS00080	COG2814	Major facilitator Superfamily
G9H43_RS00090	COG0745	RESPONSE REGULATOR receiver
G9H43_RS00095	COG2205	protein histidine kinase activity
G9H43_RS00115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9H43_RS00120	COG4191	Histidine kinase
G9H43_RS00120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS00125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9H43_RS00130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9H43_RS00135	COG1309	transcriptional regulator
G9H43_RS00165	COG0561	phosphatase activity
G9H43_RS00170	COG2267	carboxylic ester hydrolase activity
G9H43_RS00175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G9H43_RS00180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9H43_RS00185	COG1758	RNA polymerase activity
G9H43_RS00190	COG0194	GDP metabolic process
G9H43_RS00200	COG0859	PFAM glycosyl transferase family 9
G9H43_RS00205	COG3642	lipopolysaccharide core region biosynthetic process
G9H43_RS00245	COG0589	response to stress
G9H43_RS00250	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G9H43_RS00260	COG1528	Iron-storage protein
G9H43_RS00265	COG2081	HI0933 family
G9H43_RS00305	COG2197	response regulator
G9H43_RS00315	COG5433	transposase activity
G9H43_RS00320	COG2205	protein histidine kinase activity
G9H43_RS00320	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS00330	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS00330	COG2205	protein histidine kinase activity
G9H43_RS00340	COG3275	phosphorelay sensor kinase activity
G9H43_RS00345	COG3279	Response regulator of the LytR AlgR family
G9H43_RS00350	COG2223	nitrite transmembrane transporter activity
G9H43_RS00355	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
G9H43_RS00360	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
G9H43_RS00375	COG0583	DNA-binding transcription factor activity
G9H43_RS00380	COG4206	TonB-dependent receptor
G9H43_RS00385	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G9H43_RS00430	COG0583	DNA-binding transcription factor activity
G9H43_RS00435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G9H43_RS00440	COG0166	Belongs to the GPI family
G9H43_RS00450	COG0668	transmembrane transport
G9H43_RS00455	COG1309	transcriptional regulator
G9H43_RS00460	COG0756	dUTP diphosphatase activity
G9H43_RS00465	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
G9H43_RS00470	COG2003	Belongs to the UPF0758 family
G9H43_RS00475	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G9H43_RS00480	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G9H43_RS00490	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
G9H43_RS00495	COG2990	Protein conserved in bacteria
G9H43_RS00500	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G9H43_RS00505	COG0859	PFAM glycosyl transferase family 9
G9H43_RS00510	COG0463	Glycosyl transferase, family 2
G9H43_RS00515	COG0859	PFAM glycosyl transferase family 9
G9H43_RS00520	COG1519	Transferase
G9H43_RS00535	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS00540	COG1609	Transcriptional regulator
G9H43_RS00545	COG0604	alcohol dehydrogenase
G9H43_RS00570	COG1580	Controls the rotational direction of flagella during chemotaxis
G9H43_RS00575	COG3161	chorismate lyase activity
G9H43_RS00580	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G9H43_RS00585	COG2937	Belongs to the GPAT DAPAT family
G9H43_RS00590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
G9H43_RS00605	COG0534	Mate efflux family protein
G9H43_RS00610	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
G9H43_RS00615	COG2205	protein histidine kinase activity
G9H43_RS00620	COG0745	RESPONSE REGULATOR receiver
G9H43_RS00630	COG1045	serine acetyltransferase
G9H43_RS00640	COG3074	FtsZ-dependent cytokinesis
G9H43_RS00645	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
G9H43_RS00655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G9H43_RS00705	COG1609	Transcriptional regulator
G9H43_RS00710	COG0385	Bile acid
G9H43_RS00715	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G9H43_RS00735	COG0583	DNA-binding transcription factor activity
G9H43_RS00740	COG1079	Belongs to the binding-protein-dependent transport system permease family
G9H43_RS00745	COG4603	Belongs to the binding-protein-dependent transport system permease family
G9H43_RS00750	COG3845	ABC transporter
G9H43_RS00755	COG1744	ABC transporter substrate-binding protein PnrA-like
G9H43_RS00760	COG0210	DNA helicase
G9H43_RS00800	COG1280	lysine exporter protein (LysE YggA)
G9H43_RS00805	COG2391	methyltransferase activity
G9H43_RS00810	COG5433	transposase activity
G9H43_RS00820	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9H43_RS00835	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
G9H43_RS00840	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
G9H43_RS00850	COG0018	arginyl-trna synthetase
G9H43_RS00860	COG1595	DNA-templated transcription, initiation
G9H43_RS00870	COG1968	undecaprenyl-diphosphatase activity
G9H43_RS00875	COG0667	Aldo Keto reductase
G9H43_RS00880	COG2017	converts alpha-aldose to the beta-anomer
G9H43_RS00885	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G9H43_RS00895	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9H43_RS00900	COG1609	Transcriptional regulator
G9H43_RS00905	COG3250	beta-galactosidase activity
G9H43_RS00920	COG4211	Belongs to the binding-protein-dependent transport system permease family
G9H43_RS00930	COG3328	transposase activity
G9H43_RS00970	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G9H43_RS00975	COG1288	antiporter activity
G9H43_RS00980	COG1438	arginine binding
G9H43_RS00985	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
G9H43_RS00990	COG0540	Belongs to the ATCase OTCase family
G9H43_RS01005	COG0688	phosphatidylethanolamine metabolic process
G9H43_RS01015	COG3040	lipid binding
G9H43_RS01020	COG2207	Transcriptional regulator
G9H43_RS01025	COG1979	alcohol dehydrogenase
G9H43_RS01030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
G9H43_RS01035	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
G9H43_RS01045	COG2964	Protein conserved in bacteria
G9H43_RS01050	COG3681	Belongs to the UPF0597 family
G9H43_RS01060	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9H43_RS01065	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9H43_RS01070	COG0564	pseudouridine synthase activity
G9H43_RS01080	COG0542	response to heat
G9H43_RS01085	COG2502	aspartate--ammonia ligase
G9H43_RS01090	COG1522	sequence-specific DNA binding
G9H43_RS01100	COG5413	integral membrane protein
G9H43_RS01105	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G9H43_RS01105	COG0617	tRNA 3'-terminal CCA addition
G9H43_RS01105	COG0517	IMP dehydrogenase activity
G9H43_RS01110	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS01125	COG2205	protein histidine kinase activity
G9H43_RS01135	COG2204	response regulator
G9H43_RS01145	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
G9H43_RS01150	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
G9H43_RS01180	COG0243	molybdopterin cofactor binding
G9H43_RS01185	COG3005	denitrification pathway
G9H43_RS01190	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G9H43_RS01195	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9H43_RS01200	COG0569	domain protein
G9H43_RS01205	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G9H43_RS01230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9H43_RS01245	COG0250	Participates in transcription elongation, termination and antitermination
G9H43_RS01250	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G9H43_RS01255	COG0081	regulation of translation
G9H43_RS01260	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G9H43_RS01265	COG0222	ribosome binding
G9H43_RS01270	COG0085	RNA polymerase activity
G9H43_RS01275	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G9H43_RS01280	COG2964	Protein conserved in bacteria
G9H43_RS01295	COG2923	Belongs to the DsrF TusC family
G9H43_RS01300	COG2168	tRNA wobble position uridine thiolation
G9H43_RS01305	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G9H43_RS01310	COG0049	tRNA binding
G9H43_RS01315	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G9H43_RS01320	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
G9H43_RS01325	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G9H43_RS01385	COG3047	cAMP biosynthetic process
G9H43_RS01415	COG3135	benzoate transporter
G9H43_RS01420	COG1396	sequence-specific DNA binding
G9H43_RS01450	COG2926	Belongs to the UPF0265 family
G9H43_RS01460	COG3028	Belongs to the UPF0307 family
G9H43_RS01465	COG0312	modulator of DNA gyrase
G9H43_RS01470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G9H43_RS01475	COG5007	Belongs to the BolA IbaG family
G9H43_RS01485	COG2854	intermembrane phospholipid transfer
G9H43_RS01490	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G9H43_RS01495	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G9H43_RS01500	COG1127	ABC transporter
G9H43_RS01505	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G9H43_RS01505	COG0517	IMP dehydrogenase activity
G9H43_RS01510	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
G9H43_RS01515	COG3117	lipopolysaccharide transmembrane transporter activity
G9H43_RS01520	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
G9H43_RS01525	COG1137	ATPase activity
G9H43_RS01530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
G9H43_RS01540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS01545	COG1660	Displays ATPase and GTPase activities
G9H43_RS01550	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS01570	COG3964	amidohydrolase
G9H43_RS01600	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9H43_RS01605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
G9H43_RS01615	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
G9H43_RS01620	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G9H43_RS01625	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G9H43_RS01630	COG0723	plastoquinol--plastocyanin reductase activity
G9H43_RS01635	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
G9H43_RS01640	COG2857	Cytochrome c1
G9H43_RS01645	COG0625	glutathione transferase activity
G9H43_RS01650	COG2969	positive regulation of protein catabolic process
G9H43_RS01655	COG2823	Periplasmic or secreted lipoprotein
G9H43_RS01660	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G9H43_RS01665	COG0792	nuclease activity
G9H43_RS01670	COG3107	peptidoglycan biosynthetic process
G9H43_RS01675	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G9H43_RS01700	COG1987	bacterial-type flagellum assembly
G9H43_RS01750	COG2249	NAD(P)H dehydrogenase (quinone) activity
G9H43_RS01765	COG1770	oligopeptidase
G9H43_RS01785	COG3714	YhhN family
G9H43_RS01810	COG1301	dicarboxylic acid transport
G9H43_RS01820	COG2095	MarC family integral membrane protein
G9H43_RS01830	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9H43_RS01840	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9H43_RS01850	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9H43_RS01880	COG0742	ribosomal rna small subunit methyltransferase
G9H43_RS01885	COG0552	protein localization to endoplasmic reticulum
G9H43_RS01890	COG2884	Cell division ATP-binding protein ftsE
G9H43_RS01895	COG2177	Part of the ABC transporter FtsEX involved in
G9H43_RS01905	COG0288	reversible hydration of carbon dioxide
G9H43_RS01910	COG2188	Transcriptional regulator
G9H43_RS01915	COG1228	amidohydrolase
G9H43_RS01920	COG0010	Belongs to the arginase family
G9H43_RS01925	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
G9H43_RS01930	COG2986	histidine ammonia-lyase
G9H43_RS01935	COG0387	Pfam Sodium calcium exchanger
G9H43_RS01940	COG2264	protein methyltransferase activity
G9H43_RS01945	COG2200	EAL domain
G9H43_RS01945	COG2199	diguanylate cyclase activity
G9H43_RS02005	COG1077	Cell shape determining protein MreB Mrl
G9H43_RS02010	COG1792	Involved in formation and maintenance of cell shape
G9H43_RS02015	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
G9H43_RS02020	COG0424	maF-like protein
G9H43_RS02025	COG1530	ribonuclease E activity
G9H43_RS02030	COG3164	Protein of unknown function
G9H43_RS02040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9H43_RS02045	COG0312	modulator of DNA gyrase
G9H43_RS02060	COG0477	Major facilitator Superfamily
G9H43_RS02070	COG3437	response regulator, receiver
G9H43_RS02075	COG5002	protein histidine kinase activity
G9H43_RS02075	COG2205	protein histidine kinase activity
G9H43_RS02075	COG0784	Response regulator, receiver
G9H43_RS02080	COG2172	sigma factor antagonist activity
G9H43_RS02085	COG1366	Belongs to the anti-sigma-factor antagonist family
G9H43_RS02095	COG3700	Belongs to the class B bacterial acid phosphatase family
G9H43_RS02105	COG1639	'signal transduction protein
G9H43_RS02130	COG0189	ligase activity
G9H43_RS02135	COG0642	Histidine kinase
G9H43_RS02140	COG0745	RESPONSE REGULATOR receiver
G9H43_RS02175	COG0004	ammonium transporteR
G9H43_RS02180	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9H43_RS02190	COG2165	general secretion pathway protein
G9H43_RS02195	COG0084	hydrolase, TatD family'
G9H43_RS02210	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G9H43_RS02215	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
G9H43_RS02220	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
G9H43_RS02225	COG0813	purine-nucleoside phosphorylase activity
G9H43_RS02235	COG0560	Phosphoserine phosphatase
G9H43_RS02260	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
G9H43_RS02265	COG0776	regulation of translation
G9H43_RS02280	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G9H43_RS02285	COG0735	belongs to the Fur family
G9H43_RS02305	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G9H43_RS02310	COG0513	Belongs to the DEAD box helicase family
G9H43_RS02315	COG3022	response to hydroperoxide
G9H43_RS02330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
G9H43_RS02335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G9H43_RS02340	COG0762	integral membrane protein
G9H43_RS02345	COG1872	DUF167
G9H43_RS02360	COG4166	transmembrane transport
G9H43_RS02370	COG0110	maltose O-acetyltransferase activity
G9H43_RS02380	COG1024	Enoyl-CoA hydratase
G9H43_RS02395	COG4221	oxidoreductase activity
G9H43_RS02405	COG2957	Belongs to the agmatine deiminase family
G9H43_RS02420	COG3328	transposase activity
G9H43_RS02520	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
G9H43_RS02525	COG0352	thiamine-phosphate diphosphorylase activity
G9H43_RS02530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G9H43_RS02540	COG2022	thiamine diphosphate biosynthetic process
G9H43_RS02570	COG5433	transposase activity
G9H43_RS02575	COG0814	amino acid
G9H43_RS02580	COG3932	Exopolysaccharide synthesis, ExoD
G9H43_RS02630	COG1494	fructose-1,6-bisphosphatase
G9H43_RS02645	COG2959	enzyme of heme biosynthesis
G9H43_RS02655	COG0181	hydroxymethylbilane synthase activity
G9H43_RS02660	COG3072	Adenylate cyclase
G9H43_RS02665	COG0400	carboxylic ester hydrolase activity
G9H43_RS02670	COG1965	Belongs to the frataxin family
G9H43_RS02680	COG0019	diaminopimelate decarboxylase activity
G9H43_RS02685	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G9H43_RS02700	COG1011	Hydrolase
G9H43_RS02710	COG0668	transmembrane transport
G9H43_RS02720	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
G9H43_RS02725	COG0561	phosphatase activity
G9H43_RS02750	COG0842	Transport permease protein
G9H43_RS02750	COG1129	ABC transporter
G9H43_RS02760	COG1058	Belongs to the CinA family
G9H43_RS02760	COG1546	Belongs to the CinA family
G9H43_RS02765	COG1418	mRNA catabolic process
G9H43_RS02770	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
G9H43_RS02780	COG1522	sequence-specific DNA binding
G9H43_RS02785	COG1368	sulfuric ester hydrolase activity
G9H43_RS02805	COG1285	pathogenesis
G9H43_RS02825	COG4221	oxidoreductase activity
G9H43_RS02845	COG1979	alcohol dehydrogenase
G9H43_RS02855	COG2873	o-acetylhomoserine
G9H43_RS02870	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
G9H43_RS02885	COG5380	lipid catabolic process
G9H43_RS02890	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
G9H43_RS02900	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G9H43_RS02905	COG2949	membrane
G9H43_RS02910	COG3291	Pkd domain containing protein
G9H43_RS02920	COG5433	transposase activity
G9H43_RS02950	COG3188	usher protein
G9H43_RS02980	COG5433	transposase activity
G9H43_RS02990	COG0318	PFAM AMP-dependent synthetase and ligase
G9H43_RS03000	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G9H43_RS03005	COG0596	Alpha beta hydrolase
G9H43_RS03010	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G9H43_RS03015	COG1169	isochorismate synthase
G9H43_RS03020	COG1575	Belongs to the MenA family. Type 1 subfamily
G9H43_RS03045	COG0513	Belongs to the DEAD box helicase family
G9H43_RS03055	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9H43_RS03060	COG1988	membrane-bound metal-dependent
G9H43_RS03075	COG1671	Belongs to the UPF0178 family
G9H43_RS03095	COG0484	heat shock protein binding
G9H43_RS03100	COG3263	regulation of cellular component size
G9H43_RS03105	COG3722	fumarate hydratase activity
G9H43_RS03110	COG0246	Mannitol dehydrogenase
G9H43_RS03115	COG2213	PTS system mannitol-specific
G9H43_RS03115	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS03130	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
G9H43_RS03145	COG2771	luxR family
G9H43_RS03160	COG3133	Outer membrane lipoprotein
G9H43_RS03165	COG0456	acetyltransferase
G9H43_RS03185	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G9H43_RS03190	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
G9H43_RS03210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9H43_RS03215	COG1459	type II secretion system
G9H43_RS03220	COG2165	general secretion pathway protein
G9H43_RS03230	COG2165	general secretion pathway protein
G9H43_RS03235	COG4795	General secretion pathway protein
G9H43_RS03240	COG3156	type II secretion system protein K
G9H43_RS03250	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
G9H43_RS03265	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G9H43_RS03270	COG1011	Hydrolase
G9H43_RS03275	COG0494	nUDIX hydrolase
G9H43_RS03280	COG1218	3'(2'),5'-bisphosphate nucleotidase
G9H43_RS03285	COG0814	amino acid
G9H43_RS03290	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9H43_RS03305	COG0626	cystathionine gamma-synthase activity
G9H43_RS03310	COG0527	aspartate kinase activity
G9H43_RS03310	COG0460	homoserine dehydrogenase
G9H43_RS03325	COG1346	cytolysis
G9H43_RS03365	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G9H43_RS03370	COG1546	Belongs to the CinA family
G9H43_RS03375	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G9H43_RS03385	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G9H43_RS03390	COG0527	aspartate kinase activity
G9H43_RS03395	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
G9H43_RS03420	COG1686	Belongs to the peptidase S11 family
G9H43_RS03425	COG0586	Pfam SNARE associated Golgi protein
G9H43_RS03440	COG2927	DNA polymerase III (CHI subunit)
G9H43_RS03445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9H43_RS03450	COG0795	lipopolysaccharide-transporting ATPase activity
G9H43_RS03455	COG0795	lipopolysaccharide-transporting ATPase activity
G9H43_RS03470	COG0582	viral genome integration into host DNA
G9H43_RS03600	COG0513	Belongs to the DEAD box helicase family
G9H43_RS03620	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
G9H43_RS03680	COG1280	lysine exporter protein (LysE YggA)
G9H43_RS03685	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
G9H43_RS03700	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9H43_RS03730	COG0745	RESPONSE REGULATOR receiver
G9H43_RS03735	COG3104	oligopeptide transport
G9H43_RS03740	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G9H43_RS03745	COG1555	photosystem II stabilization
G9H43_RS03755	COG2350	Protein conserved in bacteria
G9H43_RS03760	COG2917	probably involved in intracellular septation
G9H43_RS03765	COG0076	glutamate decarboxylase activity
G9H43_RS03770	COG1272	protein, Hemolysin III
G9H43_RS03775	COG0569	domain protein
G9H43_RS03775	COG2985	domain, Protein
G9H43_RS03785	COG0835	chemotaxis
G9H43_RS03785	COG0784	Response regulator, receiver
G9H43_RS03790	COG2755	lipolytic protein G-D-S-L family
G9H43_RS03795	COG4181	ATPase activity
G9H43_RS03800	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
G9H43_RS03805	COG1090	epimerase
G9H43_RS03810	COG2200	EAL domain
G9H43_RS03815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9H43_RS03820	COG2234	aminopeptidase activity
G9H43_RS03820	COG4935	Belongs to the peptidase S8 family
G9H43_RS03825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G9H43_RS03830	COG3171	Protein conserved in bacteria
G9H43_RS03835	COG2066	Belongs to the glutaminase family
G9H43_RS03840	COG2897	thiosulfate sulfurtransferase activity
G9H43_RS03850	COG1132	(ABC) transporter
G9H43_RS03860	COG1012	belongs to the aldehyde dehydrogenase family
G9H43_RS03865	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
G9H43_RS03895	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
G9H43_RS03900	COG3300	MHYT domain
G9H43_RS03900	COG5001	Diguanylate cyclase
G9H43_RS03920	COG4628	conserved protein (DUF2132)
G9H43_RS03925	COG0688	phosphatidylethanolamine metabolic process
G9H43_RS03935	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
G9H43_RS03975	COG1278	Cold shock
G9H43_RS03990	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9H43_RS04045	COG0848	biopolymer transport protein
G9H43_RS04050	COG0811	peptide transport
G9H43_RS04055	COG0811	peptide transport
G9H43_RS04065	COG4206	TonB-dependent receptor
G9H43_RS04070	COG5433	transposase activity
G9H43_RS04075	COG0601	transmembrane transport
G9H43_RS04085	COG4174	ABC transporter (Permease)
G9H43_RS04090	COG4239	(ABC) transporter, permease
G9H43_RS04095	COG0747	negative chemotaxis
G9H43_RS04100	COG0444	Belongs to the ABC transporter superfamily
G9H43_RS04105	COG4608	Belongs to the ABC transporter superfamily
G9H43_RS04110	COG2195	Cleaves the N-terminal amino acid of tripeptides
G9H43_RS04120	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
G9H43_RS04125	COG1073	alpha beta
G9H43_RS04135	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G9H43_RS04140	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G9H43_RS04175	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9H43_RS04175	COG1522	sequence-specific DNA binding
G9H43_RS04180	COG2313	pseudouridylate synthase activity
G9H43_RS04190	COG5433	transposase activity
G9H43_RS04195	COG1858	cytochrome C peroxidase
G9H43_RS04240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9H43_RS04245	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9H43_RS04255	COG0318	PFAM AMP-dependent synthetase and ligase
G9H43_RS04270	COG2986	histidine ammonia-lyase
G9H43_RS04300	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9H43_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS04315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9H43_RS04325	COG0521	Mo-molybdopterin cofactor biosynthetic process
G9H43_RS04340	COG2966	Psort location CytoplasmicMembrane, score
G9H43_RS04345	COG3610	response to peptide
G9H43_RS04355	COG4175	Glycine betaine
G9H43_RS04360	COG4176	ABC-type proline glycine betaine transport system permease component
G9H43_RS04365	COG2113	Glycine betaine
G9H43_RS04370	COG0175	sulfate reduction
G9H43_RS04375	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
G9H43_RS04380	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G9H43_RS04385	COG0384	phenazine biosynthesis protein PhzF
G9H43_RS04390	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G9H43_RS04405	COG0786	glutamate:sodium symporter activity
G9H43_RS04410	COG0252	asparaginase activity
G9H43_RS04415	COG3139	Protein of unknown function (DUF1315)
G9H43_RS04435	COG0616	signal peptide processing
G9H43_RS04440	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9H43_RS04440	COG1902	pentaerythritol trinitrate reductase activity
G9H43_RS04445	COG0778	Nitroreductase
G9H43_RS04465	COG4302	ethanolamine ammonia-lyase activity
G9H43_RS04470	COG4303	Ethanolamine ammonia lyase large subunit
G9H43_RS04475	COG0531	amino acid
G9H43_RS04480	COG2264	protein methyltransferase activity
G9H43_RS04485	COG0604	alcohol dehydrogenase
G9H43_RS04490	COG0583	DNA-binding transcription factor activity
G9H43_RS04495	COG1263	PTS System
G9H43_RS04495	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9H43_RS04495	COG2190	(PTS) system
G9H43_RS04500	COG4145	pantothenate transmembrane transporter activity
G9H43_RS04505	COG3924	membrane
G9H43_RS04510	COG0439	Biotin carboxylase
G9H43_RS04515	COG0511	ligase activity, forming carbon-carbon bonds
G9H43_RS04520	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G9H43_RS04525	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9H43_RS04555	COG3381	protein complex oligomerization
G9H43_RS04565	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G9H43_RS04580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
G9H43_RS04585	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9H43_RS04585	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G9H43_RS04600	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G9H43_RS04605	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9H43_RS04610	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G9H43_RS04615	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
G9H43_RS04620	COG4172	Belongs to the ABC transporter superfamily
G9H43_RS04630	COG0601	transmembrane transport
G9H43_RS04640	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
G9H43_RS04645	COG0142	geranyltranstransferase activity
G9H43_RS04650	COG1722	exodeoxyribonuclease VII activity
G9H43_RS04655	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9H43_RS04660	COG1360	Flagellar Motor Protein
G9H43_RS04685	COG1534	Rna-binding protein
G9H43_RS04690	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
G9H43_RS04700	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G9H43_RS04705	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G9H43_RS04710	COG0149	triose-phosphate isomerase activity
G9H43_RS04715	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
G9H43_RS04730	COG0779	Required for maturation of 30S ribosomal subunits
G9H43_RS04735	COG0195	Participates in both transcription termination and antitermination
G9H43_RS04740	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G9H43_RS04745	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G9H43_RS04750	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G9H43_RS04755	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G9H43_RS04760	COG1185	polyribonucleotide nucleotidyltransferase activity
G9H43_RS04765	COG2211	Major facilitator Superfamily
G9H43_RS04770	COG3706	GGDEF domain
G9H43_RS04775	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
G9H43_RS04780	COG1422	Protein of unknown function (DUF1090)
G9H43_RS04795	COG5433	transposase activity
G9H43_RS04840	COG0312	modulator of DNA gyrase
G9H43_RS04855	COG4974	Belongs to the 'phage' integrase family
G9H43_RS04865	COG1970	mechanosensitive ion channel activity
G9H43_RS04875	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G9H43_RS04890	COG3545	Serine hydrolase
G9H43_RS04895	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9H43_RS04915	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G9H43_RS04920	COG0321	lipoyl(octanoyl) transferase activity
G9H43_RS04925	COG2921	Belongs to the UPF0250 family
G9H43_RS04930	COG1686	Belongs to the peptidase S11 family
G9H43_RS04935	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G9H43_RS04940	COG2951	lytic endotransglycosylase activity
G9H43_RS04945	COG0772	Belongs to the SEDS family
G9H43_RS04950	COG0768	penicillin binding
G9H43_RS04955	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G9H43_RS04960	COG0799	negative regulation of ribosome biogenesis
G9H43_RS04965	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G9H43_RS04985	COG0495	leucyl-tRNA aminoacylation
G9H43_RS04990	COG2888	peptidyl-tyrosine sulfation
G9H43_RS04995	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G9H43_RS05000	COG4535	Mg2 and Co2 transporter CorC
G9H43_RS05005	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G9H43_RS05010	COG1702	phosphate starvation-inducible protein PhoH
G9H43_RS05015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9H43_RS05020	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9H43_RS05030	COG3706	GGDEF domain
G9H43_RS05045	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9H43_RS05065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G9H43_RS05075	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G9H43_RS05085	COG0516	GMP reductase activity
G9H43_RS05095	COG0642	Histidine kinase
G9H43_RS05135	COG3214	Protein conserved in bacteria
G9H43_RS05155	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G9H43_RS05160	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
G9H43_RS05165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G9H43_RS05170	COG1053	succinate dehydrogenase
G9H43_RS05180	COG0584	glycerophosphoryl diester phosphodiesterase
G9H43_RS05210	COG0739	heme binding
G9H43_RS05225	COG0583	DNA-binding transcription factor activity
G9H43_RS05240	COG0840	transmembrane signaling receptor activity
G9H43_RS05245	COG0583	DNA-binding transcription factor activity
G9H43_RS05250	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
G9H43_RS05280	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G9H43_RS05285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G9H43_RS05295	COG0338	D12 class N6 adenine-specific DNA methyltransferase
G9H43_RS05300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G9H43_RS05305	COG0546	phosphoglycolate phosphatase activity
G9H43_RS05310	COG0180	Tryptophanyl-tRNA synthetase
G9H43_RS05325	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G9H43_RS05335	COG1012	belongs to the aldehyde dehydrogenase family
G9H43_RS05345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9H43_RS05365	COG0488	(ABC) transporter
G9H43_RS05375	COG0366	Alpha amylase catalytic
G9H43_RS05390	COG0443	Heat shock 70 kDa protein
G9H43_RS05425	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
G9H43_RS05435	COG0471	metal ion transport
G9H43_RS05435	COG0490	domain, Protein
G9H43_RS05480	COG0012	GTP binding
G9H43_RS05485	COG0193	aminoacyl-tRNA hydrolase activity
G9H43_RS05490	COG0737	Belongs to the 5'-nucleotidase family
G9H43_RS05495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G9H43_RS05505	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
G9H43_RS05510	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
G9H43_RS05515	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G9H43_RS05520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G9H43_RS05525	COG2890	protein-(glutamine-N5) methyltransferase activity
G9H43_RS05535	COG2912	Transglutaminase-like superfamily
G9H43_RS05570	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G9H43_RS05585	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G9H43_RS05590	COG1115	amino acid carrier protein
G9H43_RS05605	COG0714	Associated with various cellular activities
G9H43_RS05625	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G9H43_RS05630	COG1678	Uncharacterized ACR, COG1678
G9H43_RS05650	COG0189	ligase activity
G9H43_RS05655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G9H43_RS05665	COG3091	SprT-like family
G9H43_RS05675	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G9H43_RS05680	COG5433	transposase activity
G9H43_RS05700	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
G9H43_RS05705	COG0739	heme binding
G9H43_RS05710	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G9H43_RS05730	COG0463	Glycosyl transferase, family 2
G9H43_RS05745	COG2989	Protein conserved in bacteria
G9H43_RS05750	COG3108	Peptidase M15
G9H43_RS05760	COG2860	membrane
G9H43_RS05770	COG1196	nuclear chromosome segregation
G9H43_RS05775	COG3115	cell septum assembly
G9H43_RS05780	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G9H43_RS05790	COG1328	CTP reductase activity
G9H43_RS05800	COG0602	queuosine metabolic process
G9H43_RS05825	COG1566	PFAM secretion protein HlyD family protein
G9H43_RS05830	COG1846	Transcriptional regulator
G9H43_RS05845	COG0582	viral genome integration into host DNA
G9H43_RS05850	COG3264	Mechanosensitive ion channel
G9H43_RS05850	COG1196	nuclear chromosome segregation
G9H43_RS05855	COG0469	pyruvate kinase activity
G9H43_RS05880	COG0405	Gamma-glutamyltransferase
G9H43_RS05885	COG2974	May be involved in recombination
G9H43_RS05895	COG0420	3'-5' exonuclease activity
G9H43_RS05900	COG0419	ATPase involved in DNA repair
G9H43_RS05910	COG5433	transposase activity
G9H43_RS05920	COG3038	cytochrome b561
G9H43_RS05935	COG2190	(PTS) system
G9H43_RS05945	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS05950	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
G9H43_RS05970	COG1720	tRNA m6t6A37 methyltransferase activity
G9H43_RS05990	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
G9H43_RS05995	COG4988	ABC transporter
G9H43_RS06010	COG0745	RESPONSE REGULATOR receiver
G9H43_RS06020	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G9H43_RS06035	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
G9H43_RS06040	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
G9H43_RS06050	COG0083	homoserine kinase activity
G9H43_RS06055	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G9H43_RS06090	COG0813	purine-nucleoside phosphorylase activity
G9H43_RS06105	COG3384	dioxygenase
G9H43_RS06115	COG1283	sodium-dependent phosphate transmembrane transporter activity
G9H43_RS06120	COG0531	amino acid
G9H43_RS06125	COG0531	amino acid
G9H43_RS06140	COG1917	Cupin 2, conserved barrel domain protein
G9H43_RS06140	COG1396	sequence-specific DNA binding
G9H43_RS06145	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9H43_RS06155	COG2169	Transcriptional regulator
G9H43_RS06155	COG1917	Cupin 2, conserved barrel domain protein
G9H43_RS06160	COG5433	transposase activity
G9H43_RS06180	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G9H43_RS06190	COG0840	transmembrane signaling receptor activity
G9H43_RS06195	COG0835	chemotaxis
G9H43_RS06215	COG0745	RESPONSE REGULATOR receiver
G9H43_RS06225	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9H43_RS06235	COG1280	lysine exporter protein (LysE YggA)
G9H43_RS06250	COG3813	Protein conserved in bacteria
G9H43_RS06260	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G9H43_RS06275	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
G9H43_RS06300	COG0300	oxidoreductase activity
G9H43_RS06330	COG2133	pyrroloquinoline quinone binding
G9H43_RS06355	COG1605	Chorismate mutase
G9H43_RS06355	COG0077	Prephenate dehydratase
G9H43_RS06385	COG3272	Protein of unknown function (DUF1722)
G9H43_RS06390	COG0789	Transcriptional regulator
G9H43_RS06395	COG0415	Belongs to the DNA photolyase family
G9H43_RS06405	COG0300	oxidoreductase activity
G9H43_RS06420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
G9H43_RS06445	COG0783	Belongs to the Dps family
G9H43_RS06450	COG1151	hydroxylamine reductase activity
G9H43_RS06460	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9H43_RS06465	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G9H43_RS06465	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9H43_RS06475	COG3459	Glycosyltransferase 36 associated
G9H43_RS06480	COG3459	Glycosyltransferase 36 associated
G9H43_RS06500	COG0693	protein deglycase activity
G9H43_RS06505	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
G9H43_RS06510	COG1666	GTP binding
G9H43_RS06515	COG3248	Nucleoside-binding outer membrane protein
G9H43_RS06520	COG2211	Major facilitator Superfamily
G9H43_RS06530	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G9H43_RS06540	COG2813	Specifically methylates the guanine in position
G9H43_RS06545	COG0271	Belongs to the BolA IbaG family
G9H43_RS06555	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9H43_RS06560	COG1805	sodium ion transport
G9H43_RS06565	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9H43_RS06570	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9H43_RS06575	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
G9H43_RS06580	COG2871	sodium ion transport
G9H43_RS06585	COG1477	protein flavinylation
G9H43_RS06600	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G9H43_RS06605	COG0840	transmembrane signaling receptor activity
G9H43_RS06610	COG0583	DNA-binding transcription factor activity
G9H43_RS06620	COG2363	Small membrane protein
G9H43_RS06625	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
G9H43_RS06635	COG0473	3-isopropylmalate dehydrogenase activity
G9H43_RS06640	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G9H43_RS06645	COG1611	Belongs to the LOG family
G9H43_RS06660	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G9H43_RS06660	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
G9H43_RS06670	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
G9H43_RS06695	COG3098	single-species biofilm formation
G9H43_RS06700	COG0564	pseudouridine synthase activity
G9H43_RS06710	COG5433	transposase activity
G9H43_RS06715	COG4580	involved in the transport of maltose and maltodextrins
G9H43_RS06725	COG1263	PTS System
G9H43_RS06725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9H43_RS06735	COG2171	N-acyltransferase activity
G9H43_RS06745	COG0024	Methionine aminopeptidase
G9H43_RS06750	COG0052	Belongs to the universal ribosomal protein uS2 family
G9H43_RS06755	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G9H43_RS06760	COG0528	UMP kinase activity
G9H43_RS06765	COG0233	cytoplasmic translational termination
G9H43_RS06770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
G9H43_RS06775	COG0575	Belongs to the CDS family
G9H43_RS06780	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
G9H43_RS06785	COG0750	zinc metalloprotease
G9H43_RS06800	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9H43_RS06805	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G9H43_RS06810	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9H43_RS06815	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9H43_RS06820	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G9H43_RS06830	COG0825	malonyl-CoA metabolic process
G9H43_RS06835	COG3710	Transcriptional regulator
G9H43_RS06840	COG0531	amino acid
G9H43_RS06845	COG1982	Orn Lys Arg decarboxylase major
G9H43_RS06850	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G9H43_RS06865	COG0814	amino acid
G9H43_RS06870	COG0531	amino acid
G9H43_RS06880	COG0488	(ABC) transporter
G9H43_RS06890	COG3590	peptidase
G9H43_RS06895	COG0037	tRNA processing
G9H43_RS06935	COG0366	Alpha amylase catalytic
G9H43_RS06945	COG1881	PFAM PEBP family protein
G9H43_RS06950	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G9H43_RS06955	COG0583	DNA-binding transcription factor activity
G9H43_RS06965	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G9H43_RS06975	COG0583	DNA-binding transcription factor activity
G9H43_RS06980	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS06985	COG0616	signal peptide processing
G9H43_RS06990	COG3724	N-succinylarginine dihydrolase activity
G9H43_RS07010	COG0840	transmembrane signaling receptor activity
G9H43_RS07020	COG2971	BadF BadG BcrA BcrD
G9H43_RS07030	COG4608	Belongs to the ABC transporter superfamily
G9H43_RS07035	COG0444	Belongs to the ABC transporter superfamily
G9H43_RS07040	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9H43_RS07090	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
G9H43_RS07095	COG1289	transmembrane transporter activity
G9H43_RS07100	COG0303	'Molybdopterin
G9H43_RS07105	COG0746	molybdenum cofactor guanylyltransferase activity
G9H43_RS07115	COG4662	Binding-protein-dependent transport system inner membrane component
G9H43_RS07130	COG3852	Histidine kinase
G9H43_RS07140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G9H43_RS07155	COG5433	transposase activity
G9H43_RS07165	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9H43_RS07180	COG2207	Transcriptional regulator
G9H43_RS07185	COG0538	isocitrate dehydrogenase activity
G9H43_RS07230	COG0582	viral genome integration into host DNA
G9H43_RS07240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G9H43_RS07250	COG2867	negative regulation of translational initiation
G9H43_RS07255	COG2914	Belongs to the UPF0125 (RnfH) family
G9H43_RS07260	COG0702	epimerase
G9H43_RS07265	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9H43_RS07295	COG4964	Belongs to the GSP D family
G9H43_RS07305	COG2894	cell division
G9H43_RS07345	COG1454	alcohol dehydrogenase
G9H43_RS07360	COG1957	nucleoside hydrolase
G9H43_RS07380	COG0840	transmembrane signaling receptor activity
G9H43_RS07385	COG1280	lysine exporter protein (LysE YggA)
G9H43_RS07395	COG5433	transposase activity
G9H43_RS07415	COG3263	regulation of cellular component size
G9H43_RS07425	COG1876	peptidase activity
G9H43_RS07430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G9H43_RS07435	COG1393	Belongs to the ArsC family
G9H43_RS07440	COG0583	DNA-binding transcription factor activity
G9H43_RS07460	COG0017	Asparaginyl-tRNA synthetase
G9H43_RS07480	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
G9H43_RS07485	COG0156	8-amino-7-oxononanoate synthase activity
G9H43_RS07490	COG2226	methyltransferase
G9H43_RS07490	COG1073	alpha beta
G9H43_RS07495	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
G9H43_RS07500	COG0501	Belongs to the peptidase M48B family
G9H43_RS07510	COG0633	Ferredoxin
G9H43_RS07510	COG3217	Mosc domain protein beta barrel domain protein
G9H43_RS07510	COG0633	Ferredoxin
G9H43_RS07510	COG3217	Mosc domain protein beta barrel domain protein
G9H43_RS07525	COG0674	pyruvate-flavodoxin oxidoreductase activity
G9H43_RS07525	COG1013	pyruvate-flavodoxin oxidoreductase activity
G9H43_RS07525	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
G9H43_RS07525	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
G9H43_RS07530	COG2841	Protein conserved in bacteria
G9H43_RS07540	COG0534	Mate efflux family protein
G9H43_RS07580	COG1309	transcriptional regulator
G9H43_RS07595	COG0791	NLP P60 protein
G9H43_RS07605	COG0583	DNA-binding transcription factor activity
G9H43_RS07615	COG0643	Histidine kinase
G9H43_RS07615	COG2198	Histidine kinase
G9H43_RS07615	COG0784	Response regulator, receiver
G9H43_RS07620	COG2201	protein-glutamate methylesterase activity
G9H43_RS07625	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9H43_RS07630	COG1360	Flagellar Motor Protein
G9H43_RS07635	COG1192	Involved in chromosome partitioning
G9H43_RS07645	COG0835	chemotaxis
G9H43_RS07665	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9H43_RS07670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9H43_RS07675	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G9H43_RS07680	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
G9H43_RS07685	COG1138	Cytochrome C-type biogenesis protein
G9H43_RS07690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G9H43_RS07695	COG3088	subunit of a heme lyase
G9H43_RS07695	COG4235	cytochrome complex assembly
G9H43_RS07715	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
G9H43_RS07720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9H43_RS07720	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9H43_RS07735	COG0259	pyridoxamine-phosphate oxidase activity
G9H43_RS07790	COG2850	peptidyl-arginine hydroxylation
G9H43_RS07795	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
G9H43_RS07800	COG2915	High frequency lysogenization protein hflD homolog
G9H43_RS07805	COG0482	sulfurtransferase activity
G9H43_RS07825	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9H43_RS07835	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9H43_RS07835	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9H43_RS07835	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS07885	COG0159	tryptophan synthase activity
G9H43_RS07890	COG0133	tryptophan synthase activity
G9H43_RS07895	COG0134	indole-3-glycerol-phosphate synthase activity
G9H43_RS07895	COG0135	phosphoribosylanthranilate isomerase activity
G9H43_RS07900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G9H43_RS07905	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G9H43_RS07905	COG0512	Glutamine amidotransferase of anthranilate synthase
G9H43_RS07910	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G9H43_RS07920	COG0009	L-threonylcarbamoyladenylate synthase
G9H43_RS07930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
G9H43_RS07940	COG1946	Acyl-CoA thioesterase
G9H43_RS07955	COG1309	transcriptional regulator
G9H43_RS07960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9H43_RS07980	COG1091	dTDP-4-dehydrorhamnose reductase activity
G9H43_RS08000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9H43_RS08005	COG1459	type II secretion system
G9H43_RS08050	COG1450	Type ii and iii secretion system protein
G9H43_RS08075	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
G9H43_RS08105	COG5433	transposase activity
G9H43_RS08110	COG0471	metal ion transport
G9H43_RS08110	COG3273	potassium ion transport
G9H43_RS08120	COG5433	transposase activity
G9H43_RS08135	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9H43_RS08175	COG5433	transposase activity
G9H43_RS08180	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G9H43_RS08190	COG3132	Protein of unknown function, DUF480
G9H43_RS08245	COG1278	Cold shock
G9H43_RS08285	COG0697	spore germination
G9H43_RS08310	COG4166	transmembrane transport
G9H43_RS08315	COG0622	Phosphoesterase
G9H43_RS08335	COG0835	chemotaxis
G9H43_RS08335	COG0784	Response regulator, receiver
G9H43_RS08340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
G9H43_RS08345	COG1815	bacterial-type flagellum-dependent cell motility
G9H43_RS08365	COG4787	bacterial-type flagellum-dependent cell motility
G9H43_RS08375	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G9H43_RS08410	COG2239	Acts as a magnesium transporter
G9H43_RS08415	COG0248	Ppx GppA phosphatase
G9H43_RS08420	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G9H43_RS08450	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G9H43_RS08455	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
G9H43_RS08460	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
G9H43_RS08465	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G9H43_RS08485	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
G9H43_RS08495	COG0590	tRNA wobble adenosine to inosine editing
G9H43_RS08500	COG0573	inorganic phosphate transmembrane transporter activity
G9H43_RS08505	COG0581	inorganic phosphate transmembrane transporter activity
G9H43_RS08510	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
G9H43_RS08515	COG0704	Plays a role in the regulation of phosphate uptake
G9H43_RS08520	COG1253	flavin adenine dinucleotide binding
G9H43_RS08535	COG0531	amino acid
G9H43_RS08545	COG1126	abc transporter atp-binding protein
G9H43_RS08550	COG0765	amino acid transport
G9H43_RS08555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS08560	COG3706	GGDEF domain
G9H43_RS08565	COG2271	Major facilitator Superfamily
G9H43_RS08580	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G9H43_RS08600	COG1785	Belongs to the alkaline phosphatase family
G9H43_RS08605	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
G9H43_RS08620	COG1199	ATP-dependent helicase activity
G9H43_RS08635	COG1448	Aminotransferase
G9H43_RS08655	COG0658	competence protein
G9H43_RS08655	COG2333	competence protein COMEC
G9H43_RS08660	COG1132	(ABC) transporter
G9H43_RS08665	COG1663	tetraacyldisaccharide 4'-kinase activity
G9H43_RS08670	COG2835	tetraacyldisaccharide 4'-kinase activity
G9H43_RS08675	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G9H43_RS08680	COG2197	response regulator
G9H43_RS08685	COG0322	excinuclease ABC activity
G9H43_RS08725	COG2261	transglycosylase associated protein
G9H43_RS08730	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G9H43_RS08740	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G9H43_RS08775	COG2199	diguanylate cyclase activity
G9H43_RS08775	COG2203	Gaf domain
G9H43_RS08805	COG2119	membrane
G9H43_RS08850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS08850	COG2205	protein histidine kinase activity
G9H43_RS08860	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
G9H43_RS08865	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9H43_RS08870	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
G9H43_RS08875	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9H43_RS08880	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
G9H43_RS08885	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G9H43_RS08900	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G9H43_RS08905	COG0505	Belongs to the CarA family
G9H43_RS08910	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G9H43_RS08915	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9H43_RS08950	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9H43_RS08955	COG0513	Belongs to the DEAD box helicase family
G9H43_RS09005	COG0069	glutamate synthase activity
G9H43_RS09005	COG0070	glutamate synthase
G9H43_RS09005	COG0067	glutamate synthase
G9H43_RS09010	COG0493	'glutamate synthase
G9H43_RS09025	COG0789	Transcriptional regulator
G9H43_RS09045	COG3150	esterase
G9H43_RS09060	COG1252	NADH dehydrogenase
G9H43_RS09065	COG0393	Putative heavy-metal-binding
G9H43_RS09075	COG1619	proteins homologs of microcin C7 resistance protein MccF
G9H43_RS09080	COG1368	sulfuric ester hydrolase activity
G9H43_RS09090	COG0527	aspartate kinase activity
G9H43_RS09095	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
G9H43_RS09095	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G9H43_RS09100	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9H43_RS09165	COG1285	pathogenesis
G9H43_RS09180	COG0577	efflux transmembrane transporter activity
G9H43_RS09185	COG1136	(ABC) transporter
G9H43_RS09200	COG2814	Major facilitator Superfamily
G9H43_RS09225	COG0672	)-iron permease
G9H43_RS09300	COG0671	phosphoesterase, PA-phosphatase related
G9H43_RS09305	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G9H43_RS09310	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G9H43_RS09320	COG0101	tRNA pseudouridine synthase activity
G9H43_RS09325	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G9H43_RS09330	COG0285	dihydrofolate synthase activity
G9H43_RS09335	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
G9H43_RS09340	COG2920	part of a sulfur-relay system
G9H43_RS09345	COG1289	transmembrane transporter activity
G9H43_RS09350	COG0670	Belongs to the BI1 family
G9H43_RS09360	COG0840	transmembrane signaling receptor activity
G9H43_RS09365	COG5001	Diguanylate cyclase
G9H43_RS09380	COG0564	pseudouridine synthase activity
G9H43_RS09405	COG0625	glutathione transferase activity
G9H43_RS09410	COG0625	glutathione transferase activity
G9H43_RS09435	COG0367	asparagine synthase
G9H43_RS09445	COG4651	solute:proton antiporter activity
G9H43_RS09445	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
G9H43_RS09450	COG0647	UMP catabolic process
G9H43_RS09460	COG1902	pentaerythritol trinitrate reductase activity
G9H43_RS09465	COG1253	flavin adenine dinucleotide binding
G9H43_RS09475	COG0247	lactate metabolic process
G9H43_RS09475	COG0277	FAD linked oxidase domain protein
G9H43_RS09485	COG2050	protein possibly involved in aromatic compounds catabolism
G9H43_RS09490	COG0513	Belongs to the DEAD box helicase family
G9H43_RS09500	COG3300	MHYT domain
G9H43_RS09500	COG5001	Diguanylate cyclase
G9H43_RS09505	COG2056	Na+-H+ antiporter family
G9H43_RS09510	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G9H43_RS09525	COG0346	lactoylglutathione lyase activity
G9H43_RS09530	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G9H43_RS09535	COG4660	Part of a membrane complex involved in electron transport
G9H43_RS09540	COG4659	FMN binding
G9H43_RS09545	COG4658	electron transport chain
G9H43_RS09555	COG2878	Part of a membrane complex involved in electron transport
G9H43_RS09560	COG4657	Part of a membrane complex involved in electron transport
G9H43_RS09565	COG0697	spore germination
G9H43_RS09615	COG0659	secondary active sulfate transmembrane transporter activity
G9H43_RS09685	COG3829	transcription factor binding
G9H43_RS09745	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G9H43_RS09750	COG1278	Cold shock
G9H43_RS09755	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
G9H43_RS09760	COG0542	response to heat
G9H43_RS09765	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G9H43_RS09770	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
G9H43_RS09775	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G9H43_RS09780	COG3134	Outer membrane lipoprotein
G9H43_RS09790	COG0492	ferredoxin-NADP+ reductase activity
G9H43_RS09810	COG1674	ftsk spoiiie
G9H43_RS09810	COG0531	amino acid
G9H43_RS09815	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
G9H43_RS09820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G9H43_RS09825	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G9H43_RS09830	COG1286	toxin biosynthetic process
G9H43_RS09835	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
G9H43_RS09845	COG4172	Belongs to the ABC transporter superfamily
G9H43_RS09850	COG4172	Belongs to the ABC transporter superfamily
G9H43_RS09855	COG4171	peptide transport system, permease
G9H43_RS09860	COG4168	peptide transport system, permease
G9H43_RS09875	COG1842	Phage shock protein A
G9H43_RS09890	COG3106	COG3106 Predicted ATPase
G9H43_RS09895	COG3768	UPF0283 membrane protein
G9H43_RS09905	COG2154	pterin-4-alpha-carbinolamine dehydratase
G9H43_RS09920	COG2199	diguanylate cyclase activity
G9H43_RS09930	COG0861	Integral membrane protein TerC family
G9H43_RS09945	COG1022	Amp-dependent synthetase and ligase
G9H43_RS09950	COG0295	cytidine deaminase activity
G9H43_RS09955	COG1346	cytolysis
G9H43_RS09960	COG1380	Effector of murein hydrolase LrgA
G9H43_RS09970	COG3345	alpha-galactosidase
G9H43_RS09980	COG2925	Exonuclease
G9H43_RS09995	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9H43_RS10000	COG0436	Aminotransferase
G9H43_RS10005	COG0583	DNA-binding transcription factor activity
G9H43_RS10010	COG2160	L-arabinose isomerase activity
G9H43_RS10020	COG1069	ribulokinase activity
G9H43_RS10025	COG1879	ABC-type sugar transport system periplasmic component
G9H43_RS10030	COG1129	ABC transporter
G9H43_RS10035	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9H43_RS10045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
G9H43_RS10065	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G9H43_RS10070	COG1609	Transcriptional regulator
G9H43_RS10075	COG4580	involved in the transport of maltose and maltodextrins
G9H43_RS10105	COG2182	Extracellular solute-binding protein
G9H43_RS10125	COG1175	transmembrane transport
G9H43_RS10130	COG3833	ABC-type maltose transport systems, permease component
G9H43_RS10135	COG3867	Arabinogalactan endo-beta-1,4-galactanase
G9H43_RS10155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G9H43_RS10160	COG0254	rRNA binding
G9H43_RS10175	COG1451	nucleotide metabolic process
G9H43_RS10190	COG3069	C4-dicarboxylate transmembrane transporter activity
G9H43_RS10200	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G9H43_RS10200	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9H43_RS10205	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9H43_RS10230	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
G9H43_RS10235	COG1053	succinate dehydrogenase
G9H43_RS10245	COG0567	Dehydrogenase, E1 component
G9H43_RS10250	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9H43_RS10255	COG0045	succinate-CoA ligase (ADP-forming) activity
G9H43_RS10260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G9H43_RS10265	COG2983	Belongs to the UPF0260 family
G9H43_RS10270	COG1882	Formate acetyltransferase
G9H43_RS10275	COG2116	formate transmembrane transporter activity
G9H43_RS10280	COG1944	ATP diphosphatase activity
G9H43_RS10285	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G9H43_RS10305	COG2910	NAD(P)H-binding
G9H43_RS10310	COG0583	DNA-binding transcription factor activity
G9H43_RS10320	COG3708	Transcriptional regulator
G9H43_RS10320	COG2207	Transcriptional regulator
G9H43_RS10325	COG4774	siderophore transport
G9H43_RS10335	COG0583	DNA-binding transcription factor activity
G9H43_RS10340	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G9H43_RS10370	COG3046	protein related to deoxyribodipyrimidine photolyase
G9H43_RS10380	COG3033	Beta-eliminating lyase
G9H43_RS10395	COG4235	cytochrome complex assembly
G9H43_RS10395	COG3088	subunit of a heme lyase
G9H43_RS10410	COG3301	Polysulphide reductase, NrfD
G9H43_RS10415	COG0437	4 iron, 4 sulfur cluster binding
G9H43_RS10420	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
G9H43_RS10430	COG0247	lactate metabolic process
G9H43_RS10435	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
G9H43_RS10440	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G9H43_RS10445	COG3012	SEC-C Motif Domain Protein
G9H43_RS10450	COG0840	transmembrane signaling receptor activity
G9H43_RS10455	COG1846	Transcriptional regulator
G9H43_RS10455	COG1940	carbohydrate kinase activity
G9H43_RS10460	COG3290	protein histidine kinase activity
G9H43_RS10465	COG4565	transcriptional regulatory protein
G9H43_RS10495	COG5433	transposase activity
G9H43_RS10500	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9H43_RS10505	COG0569	domain protein
G9H43_RS10505	COG2985	domain, Protein
G9H43_RS10515	COG0556	nucleotide-excision repair
G9H43_RS10525	COG0586	Pfam SNARE associated Golgi protein
G9H43_RS10530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
G9H43_RS10535	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9H43_RS10540	COG2186	Transcriptional regulator
G9H43_RS10545	COG2719	SpoVR family
G9H43_RS10555	COG2766	serine protein kinase
G9H43_RS10560	COG0514	ATP-dependent DNA helicase (RecQ)
G9H43_RS10565	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
G9H43_RS10570	COG0814	amino acid
G9H43_RS10650	COG0058	SHG alpha-glucan phosphorylase activity
G9H43_RS10655	COG0471	metal ion transport
G9H43_RS10660	COG3118	belongs to the thioredoxin family
G9H43_RS10675	COG1132	(ABC) transporter
G9H43_RS10685	COG2501	S4 domain
G9H43_RS10695	COG3243	poly(R)-hydroxyalkanoic acid synthase
G9H43_RS10715	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
G9H43_RS10720	COG2329	Antibiotic biosynthesis monooxygenase
G9H43_RS10760	COG1742	UPF0060 membrane protein
G9H43_RS10775	COG0513	Belongs to the DEAD box helicase family
G9H43_RS10780	COG0386	Belongs to the glutathione peroxidase family
G9H43_RS10790	COG1181	Belongs to the D-alanine--D-alanine ligase family
G9H43_RS10800	COG3148	PFAM DTW domain containing protein
G9H43_RS10805	COG0730	response to heat
G9H43_RS10810	COG0583	DNA-binding transcription factor activity
G9H43_RS10825	COG3593	DNA synthesis involved in DNA repair
G9H43_RS10880	COG1011	Hydrolase
G9H43_RS10920	COG0205	6-phosphofructokinase activity
G9H43_RS10930	COG1434	Gram-negative-bacterium-type cell wall biogenesis
G9H43_RS10940	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9H43_RS10950	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
G9H43_RS10955	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
G9H43_RS10960	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
G9H43_RS10985	COG0242	peptide deformylase activity
G9H43_RS11025	COG4681	YaeQ
G9H43_RS11045	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9H43_RS11065	COG3134	Outer membrane lipoprotein
G9H43_RS11075	COG1288	antiporter activity
G9H43_RS11095	COG0583	DNA-binding transcription factor activity
G9H43_RS11100	COG2723	6-phospho-beta-galactosidase activity
G9H43_RS11110	COG0583	DNA-binding transcription factor activity
G9H43_RS11115	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
G9H43_RS11120	COG0673	inositol 2-dehydrogenase activity
G9H43_RS11125	COG0583	DNA-binding transcription factor activity
G9H43_RS11135	COG1560	Kdo2-lipid A biosynthetic process
G9H43_RS11155	COG2203	Gaf domain
G9H43_RS11155	COG2199	diguanylate cyclase activity
G9H43_RS11165	COG0417	DNA replication proofreading
G9H43_RS11200	COG0534	Mate efflux family protein
G9H43_RS11210	COG0307	riboflavin synthase, alpha
G9H43_RS11220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9H43_RS11225	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
G9H43_RS11230	COG0697	spore germination
G9H43_RS11235	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
G9H43_RS11280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9H43_RS11285	COG3099	Belongs to the UPF0263 family
G9H43_RS11290	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
G9H43_RS11295	COG2894	cell division
G9H43_RS11300	COG0850	regulation of cytokinetic process
G9H43_RS11305	COG3100	YcgL domain-containing protein
G9H43_RS11310	COG2951	lytic endotransglycosylase activity
G9H43_RS11315	COG1760	l-serine dehydratase
G9H43_RS11320	COG1760	l-serine dehydratase
G9H43_RS11325	COG3123	guanosine phosphorylase activity
G9H43_RS11345	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
G9H43_RS11350	COG2067	long-chain fatty acid transport protein
G9H43_RS11355	COG2067	long-chain fatty acid transport protein
G9H43_RS11395	COG0714	Associated with various cellular activities
G9H43_RS11400	COG0183	Belongs to the thiolase family
G9H43_RS11405	COG1024	Enoyl-CoA hydratase
G9H43_RS11405	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9H43_RS11410	COG2824	Alkylphosphonate utilization operon protein PhnA
G9H43_RS11455	COG3706	GGDEF domain
G9H43_RS11460	COG2840	Smr protein MutS2
G9H43_RS11465	COG2890	protein-(glutamine-N5) methyltransferase activity
G9H43_RS11470	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G9H43_RS11480	COG0513	Belongs to the DEAD box helicase family
G9H43_RS11485	COG5654	RES domain protein
G9H43_RS11495	COG0814	amino acid
G9H43_RS11500	COG1609	Transcriptional regulator
G9H43_RS11505	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS11505	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS11510	COG1105	Belongs to the carbohydrate kinase PfkB family
G9H43_RS11515	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9H43_RS11515	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9H43_RS11515	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
G9H43_RS11520	COG3313	Fe-S protein
G9H43_RS11525	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
G9H43_RS11530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9H43_RS11535	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9H43_RS11540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9H43_RS11550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
G9H43_RS11575	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G9H43_RS11580	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G9H43_RS11585	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G9H43_RS11590	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G9H43_RS11595	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G9H43_RS11600	COG0072	phenylalanine-tRNA ligase activity
G9H43_RS11600	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9H43_RS11605	COG0776	regulation of translation
G9H43_RS11645	COG2199	diguanylate cyclase activity
G9H43_RS11650	COG1609	Transcriptional regulator
G9H43_RS11655	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9H43_RS11660	COG1879	ABC-type sugar transport system periplasmic component
G9H43_RS11665	COG1172	Belongs to the binding-protein-dependent transport system permease family
G9H43_RS11675	COG1869	D-ribose catabolic process
G9H43_RS11695	COG0037	tRNA processing
G9H43_RS11700	COG0589	response to stress
G9H43_RS11705	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9H43_RS11720	COG2217	Heavy metal translocating P-type atpase
G9H43_RS11730	COG2010	Cytochrome c
G9H43_RS11745	COG3278	Belongs to the heme-copper respiratory oxidase family
G9H43_RS11755	COG1956	GAF domain-containing protein
G9H43_RS11760	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
G9H43_RS11770	COG0308	aminopeptidase N
G9H43_RS11785	COG5433	transposase activity
G9H43_RS11795	COG0167	dihydroorotate dehydrogenase activity
G9H43_RS11810	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G9H43_RS11810	COG0116	Belongs to the methyltransferase superfamily
G9H43_RS11820	COG0488	(ABC) transporter
G9H43_RS11835	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G9H43_RS11840	COG1067	ATP-dependent peptidase activity
G9H43_RS11855	COG5433	transposase activity
G9H43_RS11915	COG3620	sequence-specific DNA binding
G9H43_RS11945	COG4221	oxidoreductase activity
G9H43_RS11990	COG0372	Belongs to the citrate synthase family
G9H43_RS11995	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
G9H43_RS12005	COG2995	paraquat-inducible protein a
G9H43_RS12015	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9H43_RS12015	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
G9H43_RS12030	COG0084	hydrolase, TatD family'
G9H43_RS12035	COG0470	DNA polymerase III
G9H43_RS12040	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
G9H43_RS12045	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G9H43_RS12050	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G9H43_RS12055	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G9H43_RS12060	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G9H43_RS12065	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS12075	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G9H43_RS12080	COG0416	fatty acid biosynthetic process
G9H43_RS12085	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G9H43_RS12090	COG1399	metal-binding, possibly nucleic acid-binding protein
G9H43_RS12100	COG0546	phosphoglycolate phosphatase activity
G9H43_RS12110	COG1530	ribonuclease E activity
G9H43_RS12115	COG0306	phosphate transporter
G9H43_RS12120	COG0717	Belongs to the dCTP deaminase family
G9H43_RS12125	COG0572	uridine kinase
G9H43_RS12130	COG0489	protein tyrosine kinase activity
G9H43_RS12135	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9H43_RS12135	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G9H43_RS12140	COG0625	glutathione transferase activity
G9H43_RS12145	COG1254	Belongs to the acylphosphatase family
G9H43_RS12155	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G9H43_RS12170	COG0709	Synthesizes selenophosphate from selenide and ATP
G9H43_RS12175	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
G9H43_RS12180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9H43_RS12185	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G9H43_RS12195	COG1643	Atp-dependent helicase
G9H43_RS12200	COG0517	IMP dehydrogenase activity
G9H43_RS12200	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G9H43_RS12200	COG0617	tRNA 3'-terminal CCA addition
G9H43_RS12205	COG2197	response regulator
G9H43_RS12210	COG3314	Sporulation integral membrane protein YlbJ
G9H43_RS12215	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
G9H43_RS12220	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G9H43_RS12225	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G9H43_RS12230	COG2832	Protein of unknown function (DUF454)
G9H43_RS12235	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
G9H43_RS12255	COG0318	PFAM AMP-dependent synthetase and ligase
G9H43_RS12260	COG2267	carboxylic ester hydrolase activity
G9H43_RS12270	COG1214	PFAM Peptidase M22, glycoprotease
G9H43_RS12275	COG1199	ATP-dependent helicase activity
G9H43_RS12285	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G9H43_RS12290	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G9H43_RS12295	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
G9H43_RS12300	COG0131	Imidazoleglycerol-phosphate dehydratase
G9H43_RS12300	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
G9H43_RS12305	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G9H43_RS12310	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G9H43_RS12315	COG3437	response regulator, receiver
G9H43_RS12320	COG2199	diguanylate cyclase activity
G9H43_RS12325	COG0784	Response regulator, receiver
G9H43_RS12325	COG2198	Histidine kinase
G9H43_RS12325	COG2205	protein histidine kinase activity
G9H43_RS12330	COG0107	imidazoleglycerol-phosphate synthase activity
G9H43_RS12335	COG0140	phosphoribosyl-ATP diphosphatase activity
G9H43_RS12335	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G9H43_RS12345	COG2378	regulation of single-species biofilm formation
G9H43_RS12375	COG0730	response to heat
G9H43_RS12385	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS12395	COG1024	Enoyl-CoA hydratase
G9H43_RS12400	COG1024	Enoyl-CoA hydratase
G9H43_RS12405	COG1960	acyl-CoA dehydrogenase activity
G9H43_RS12430	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
G9H43_RS12435	COG1024	Enoyl-CoA hydratase
G9H43_RS12465	COG1584	GPR1 FUN34 yaaH family protein
G9H43_RS12475	COG0456	acetyltransferase
G9H43_RS12480	COG1115	amino acid carrier protein
G9H43_RS12485	COG1024	Enoyl-CoA hydratase
G9H43_RS12485	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9H43_RS12500	COG3162	membrane
G9H43_RS12505	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9H43_RS12510	COG0488	(ABC) transporter
G9H43_RS12515	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G9H43_RS12520	COG0776	regulation of translation
G9H43_RS12525	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G9H43_RS12530	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G9H43_RS12535	COG0740	serine-type endopeptidase activity
G9H43_RS12540	COG0544	peptidyl-prolyl cis-trans isomerase activity
G9H43_RS12550	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
G9H43_RS12555	COG4591	ABC-type transport system involved in lipoprotein release permease component
G9H43_RS12560	COG1136	(ABC) transporter
G9H43_RS12565	COG4591	ABC-type transport system involved in lipoprotein release permease component
G9H43_RS12575	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G9H43_RS12580	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G9H43_RS12585	COG4166	transmembrane transport
G9H43_RS12590	COG0697	spore germination
G9H43_RS12600	COG2062	phosphohistidine phosphatase, SixA
G9H43_RS12660	COG0519	Catalyzes the synthesis of GMP from XMP
G9H43_RS12660	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G9H43_RS12665	COG0517	IMP dehydrogenase activity
G9H43_RS12665	COG0516	GMP reductase activity
G9H43_RS12690	COG5433	transposase activity
G9H43_RS12695	COG3038	cytochrome b561
G9H43_RS12710	COG1570	exodeoxyribonuclease VII activity
G9H43_RS12725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9H43_RS12730	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
G9H43_RS12735	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G9H43_RS12780	COG4771	TonB-dependent receptor
G9H43_RS12785	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9H43_RS12790	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9H43_RS12795	COG1120	ATPase activity
G9H43_RS12800	COG2977	Belongs to the P-Pant transferase superfamily
G9H43_RS12805	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9H43_RS12810	COG3321	synthase
G9H43_RS12810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9H43_RS12810	COG0300	oxidoreductase activity
G9H43_RS12810	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS12810	COG0318	PFAM AMP-dependent synthetase and ligase
G9H43_RS12820	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS12825	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9H43_RS12830	COG1535	isochorismatase
G9H43_RS12830	COG3433	isochorismatase activity
G9H43_RS12835	COG1021	2,3-dihydroxybenzoate-AMP ligase
G9H43_RS12890	COG0840	transmembrane signaling receptor activity
G9H43_RS12895	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9H43_RS12900	COG3788	relative of glutathione S-transferase, MAPEG superfamily
G9H43_RS12905	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G9H43_RS12910	COG0563	adenylate kinase activity
G9H43_RS12915	COG0326	Molecular chaperone. Has ATPase activity
G9H43_RS12920	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G9H43_RS12960	COG3158	transport of potassium into the cell
G9H43_RS12975	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9H43_RS12980	COG0651	ATP synthesis coupled electron transport
G9H43_RS12985	COG0650	Formate hydrogenlyase subunit 4
G9H43_RS12990	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
G9H43_RS12990	COG3261	NADH dehydrogenase
G9H43_RS12995	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9H43_RS13000	COG3260	NADH ubiquinone oxidoreductase 20
G9H43_RS13010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G9H43_RS13020	COG1921	L-seryl-tRNASec selenium transferase activity
G9H43_RS13030	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
G9H43_RS13035	COG0298	carbon dioxide binding
G9H43_RS13045	COG0309	Hydrogenase expression formation protein (HypE)
G9H43_RS13050	COG0375	protein maturation
G9H43_RS13060	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
G9H43_RS13075	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9H43_RS13080	COG0601	transmembrane transport
G9H43_RS13090	COG1773	rubredoxin
G9H43_RS13095	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
G9H43_RS13100	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
G9H43_RS13105	COG5557	Pfam Polysulphide reductase, NrfD
G9H43_RS13110	COG0437	4 iron, 4 sulfur cluster binding
G9H43_RS13120	COG5433	transposase activity
G9H43_RS13135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9H43_RS13155	COG1435	thymidine kinase activity
G9H43_RS13160	COG1757	Na H antiporter
G9H43_RS13175	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9H43_RS13180	COG2096	Adenosyltransferase
G9H43_RS13185	COG3530	Putative quorum-sensing-regulated virulence factor
G9H43_RS13190	COG0602	queuosine metabolic process
G9H43_RS13195	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
G9H43_RS13210	COG0284	orotidine-5'-phosphate decarboxylase activity
G9H43_RS13215	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
G9H43_RS13225	COG0776	regulation of translation
G9H43_RS13230	COG0539	negative regulation of cytoplasmic translation
G9H43_RS13235	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G9H43_RS13240	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9H43_RS13255	COG2814	Major facilitator Superfamily
G9H43_RS13275	COG3300	MHYT domain
G9H43_RS13275	COG5001	Diguanylate cyclase
G9H43_RS13290	COG0583	DNA-binding transcription factor activity
G9H43_RS13295	COG3437	response regulator, receiver
G9H43_RS13320	COG4989	oxidoreductase activity
G9H43_RS13325	COG0724	RNA recognition motif
G9H43_RS13335	COG1126	abc transporter atp-binding protein
G9H43_RS13340	COG0765	amino acid transport
G9H43_RS13345	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS13350	COG4597	amino acid ABC transporter
G9H43_RS13365	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
G9H43_RS13385	COG1360	Flagellar Motor Protein
G9H43_RS13390	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9H43_RS13395	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9H43_RS13400	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9H43_RS13400	COG0649	NAD binding
G9H43_RS13415	COG1034	ATP synthesis coupled electron transport
G9H43_RS13420	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G9H43_RS13425	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9H43_RS13430	COG0839	Belongs to the complex I subunit 6 family
G9H43_RS13435	COG0713	ATP synthesis coupled electron transport
G9H43_RS13445	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G9H43_RS13450	COG1007	ATP synthesis coupled electron transport
G9H43_RS13485	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9H43_RS13490	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9H43_RS13525	COG0537	adenosine 5'-monophosphoramidase activity
G9H43_RS13540	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G9H43_RS13555	COG1301	dicarboxylic acid transport
G9H43_RS13565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9H43_RS13570	COG0861	Integral membrane protein TerC family
G9H43_RS13585	COG0444	Belongs to the ABC transporter superfamily
G9H43_RS13590	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9H43_RS13595	COG0601	transmembrane transport
G9H43_RS13605	COG2095	MarC family integral membrane protein
G9H43_RS13615	COG1012	belongs to the aldehyde dehydrogenase family
G9H43_RS13615	COG1454	alcohol dehydrogenase
G9H43_RS13635	COG3275	phosphorelay sensor kinase activity
G9H43_RS13640	COG3279	Response regulator of the LytR AlgR family
G9H43_RS13645	COG1966	Carbon starvation protein
G9H43_RS13655	COG1566	PFAM secretion protein HlyD family protein
G9H43_RS13660	COG1061	Type III restriction enzyme res subunit
G9H43_RS13665	COG2027	D-alanyl-D-alanine carboxypeptidase
G9H43_RS13670	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
G9H43_RS13680	COG0436	Aminotransferase
G9H43_RS13685	COG1288	antiporter activity
G9H43_RS13690	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G9H43_RS13770	COG1242	4 iron, 4 sulfur cluster binding
G9H43_RS13775	COG5433	transposase activity
G9H43_RS13810	COG2354	Protein conserved in bacteria
G9H43_RS13820	COG0047	phosphoribosylformylglycinamidine synthase activity
G9H43_RS13820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
G9H43_RS13825	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
G9H43_RS13835	COG1645	bacterial-type flagellum-dependent swarming motility
G9H43_RS13840	COG1160	GTP binding
G9H43_RS13845	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G9H43_RS13850	COG2976	Protein conserved in bacteria
G9H43_RS13855	COG0124	histidyl-tRNA synthetase
G9H43_RS13860	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
G9H43_RS13865	COG1426	Protein conserved in bacteria
G9H43_RS13875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G9H43_RS13880	COG0105	UTP biosynthetic process
G9H43_RS13885	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
G9H43_RS13895	COG0633	Ferredoxin
G9H43_RS13900	COG0443	Heat shock 70 kDa protein
G9H43_RS13905	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G9H43_RS13915	COG0822	iron-sulfur transferase activity
G9H43_RS13920	COG1104	cysteine desulfurase activity
G9H43_RS13925	COG1959	2 iron, 2 sulfur cluster binding
G9H43_RS13940	COG3154	lipid carrier protein
G9H43_RS13945	COG0826	peptidase U32
G9H43_RS13950	COG0826	peptidase U32
G9H43_RS13960	COG2897	thiosulfate sulfurtransferase activity
G9H43_RS13965	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9H43_RS13970	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G9H43_RS13975	COG1862	Preprotein translocase
G9H43_RS13980	COG0343	queuine tRNA-ribosyltransferase activity
G9H43_RS13985	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G9H43_RS13990	COG0517	IMP dehydrogenase activity
G9H43_RS14000	COG3634	alkyl hydroperoxide reductase activity
G9H43_RS14015	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G9H43_RS14015	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
G9H43_RS14020	COG0509	glycine decarboxylation via glycine cleavage system
G9H43_RS14025	COG0404	The glycine cleavage system catalyzes the degradation of glycine
G9H43_RS14030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9H43_RS14035	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
G9H43_RS14055	COG0243	molybdopterin cofactor binding
G9H43_RS14060	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
G9H43_RS14065	COG0583	DNA-binding transcription factor activity
G9H43_RS14070	COG2814	Major facilitator Superfamily
G9H43_RS14075	COG0444	Belongs to the ABC transporter superfamily
G9H43_RS14080	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
G9H43_RS14085	COG0601	transmembrane transport
G9H43_RS14095	COG0625	glutathione transferase activity
G9H43_RS14105	COG0483	inositol monophosphate 1-phosphatase activity
G9H43_RS14125	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
G9H43_RS14135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9H43_RS14165	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
G9H43_RS14180	COG0301	tRNA thio-modification
G9H43_RS14180	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9H43_RS14190	COG4953	penicillin-binding protein 1C
G9H43_RS14195	COG2373	Large extracellular alpha-helical protein
G9H43_RS14200	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9H43_RS14210	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
G9H43_RS14245	COG2431	L-lysine efflux transmembrane transporter activity
G9H43_RS14250	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
G9H43_RS14260	COG1393	Belongs to the ArsC family
G9H43_RS14270	COG4783	chaperone-mediated protein folding
G9H43_RS14275	COG0425	Belongs to the sulfur carrier protein TusA family
G9H43_RS14280	COG0628	permease
G9H43_RS14295	COG3842	ATPase activity
G9H43_RS14300	COG3833	ABC-type maltose transport systems, permease component
G9H43_RS14305	COG1175	transmembrane transport
G9H43_RS14310	COG2182	Extracellular solute-binding protein
G9H43_RS14315	COG3081	Nucleoid-associated protein
G9H43_RS14320	COG3082	Protein of unknown function (DUF1414)
G9H43_RS14325	COG3083	sulfuric ester hydrolase activity
G9H43_RS14345	COG1770	oligopeptidase
G9H43_RS14365	COG4574	serine-type endopeptidase inhibitor activity
G9H43_RS14370	COG3085	chromosome segregation
G9H43_RS14375	COG0583	DNA-binding transcription factor activity
G9H43_RS14380	COG0287	Prephenate dehydrogenase
G9H43_RS14380	COG1605	Chorismate mutase
G9H43_RS14385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9H43_RS14390	COG0584	glycerophosphoryl diester phosphodiesterase
G9H43_RS14395	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G9H43_RS14405	COG1349	DNA-binding transcription factor activity
G9H43_RS14410	COG2271	Major facilitator Superfamily
G9H43_RS14415	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9H43_RS14420	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G9H43_RS14425	COG0583	DNA-binding transcription factor activity
G9H43_RS14450	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
G9H43_RS14455	COG0656	L-ascorbic acid biosynthetic process
G9H43_RS14460	COG2814	Major facilitator Superfamily
G9H43_RS14490	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9H43_RS14495	COG2979	Protein of unknown function (DUF533)
G9H43_RS14515	COG0583	DNA-binding transcription factor activity
G9H43_RS14525	COG2807	transmembrane transport
G9H43_RS14530	COG1187	pseudouridine synthase activity
G9H43_RS14535	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
G9H43_RS14545	COG0346	lactoylglutathione lyase activity
G9H43_RS14560	COG1166	arginine decarboxylase activity
G9H43_RS14565	COG2195	Cleaves the N-terminal amino acid of tripeptides
G9H43_RS14590	COG2353	YceI-like domain
G9H43_RS14595	COG0583	DNA-binding transcription factor activity
G9H43_RS14605	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G9H43_RS14610	COG0840	transmembrane signaling receptor activity
G9H43_RS14615	COG0302	gtp cyclohydrolase
G9H43_RS14625	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
G9H43_RS14650	COG0596	Alpha beta hydrolase
G9H43_RS14655	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
G9H43_RS14670	COG0314	molybdopterin synthase activity
G9H43_RS14675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
G9H43_RS14680	COG0315	cyclic pyranopterin monophosphate synthase activity
G9H43_RS14685	COG0521	Mo-molybdopterin cofactor biosynthetic process
G9H43_RS14690	COG3005	denitrification pathway
G9H43_RS14700	COG0348	domain, Protein
G9H43_RS14705	COG0437	4 iron, 4 sulfur cluster binding
G9H43_RS14710	COG0243	molybdopterin cofactor binding
G9H43_RS14720	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9H43_RS14725	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
G9H43_RS14730	COG3850	Histidine kinase
G9H43_RS14735	COG2197	response regulator
G9H43_RS14765	COG0121	glutamine amidotransferase
G9H43_RS14770	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
G9H43_RS14775	COG1960	acyl-CoA dehydrogenase activity
G9H43_RS14780	COG0784	Response regulator, receiver
G9H43_RS14780	COG3437	response regulator, receiver
G9H43_RS14790	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G9H43_RS14795	COG0328	RNA-DNA hybrid ribonuclease activity
G9H43_RS14800	COG2226	methyltransferase
G9H43_RS14805	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G9H43_RS14810	COG0741	lytic transglycosylase activity
G9H43_RS14810	COG1388	LysM domain
G9H43_RS14815	COG3021	interspecies interaction between organisms
G9H43_RS14820	COG1607	acyl-coa hydrolase
G9H43_RS14845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G9H43_RS14860	COG2911	Protein conserved in bacteria
G9H43_RS14865	COG0729	surface antigen
G9H43_RS14880	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G9H43_RS14885	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G9H43_RS14895	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G9H43_RS14900	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9H43_RS14905	COG4134	Bacterial extracellular solute-binding protein
G9H43_RS14910	COG4135	transport system, permease component
G9H43_RS14915	COG4136	ATPase activity
G9H43_RS14920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
G9H43_RS14925	COG2951	lytic endotransglycosylase activity
G9H43_RS14930	COG1846	Transcriptional regulator
G9H43_RS14940	COG0033	Phosphoglucomutase
G9H43_RS14945	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
G9H43_RS14950	COG0596	Alpha beta hydrolase
G9H43_RS14965	COG0716	FMN binding
G9H43_RS14975	COG0735	belongs to the Fur family
G9H43_RS14980	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9H43_RS15000	COG0363	glucosamine-6-phosphate deaminase activity
G9H43_RS15005	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
G9H43_RS15010	COG1846	Transcriptional regulator
G9H43_RS15010	COG1940	carbohydrate kinase activity
G9H43_RS15080	COG0217	transcriptional regulatory protein
G9H43_RS15085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G9H43_RS15105	COG4106	trans-aconitate 2-methyltransferase activity
G9H43_RS15110	COG0500	methyltransferase
G9H43_RS15130	COG0450	alkyl hydroperoxide reductase
G9H43_RS15140	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
G9H43_RS15165	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
G9H43_RS15175	COG1684	flagellar biosynthetic protein fliR
G9H43_RS15230	COG1342	Belongs to the UPF0251 family
G9H43_RS15250	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G9H43_RS15275	COG1737	Transcriptional regulator
G9H43_RS15280	COG0469	pyruvate kinase activity
G9H43_RS15290	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9H43_RS15295	COG1960	acyl-CoA dehydrogenase activity
G9H43_RS15350	COG1388	LysM domain
G9H43_RS15350	COG1376	ErfK ybiS ycfS ynhG family protein
G9H43_RS15365	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
G9H43_RS15370	COG0791	NLP P60 protein
G9H43_RS15375	COG2091	lysine biosynthetic process via aminoadipic acid
G9H43_RS15380	COG3118	belongs to the thioredoxin family
G9H43_RS15390	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G9H43_RS15395	COG0788	formyltetrahydrofolate deformylase activity
G9H43_RS15405	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9H43_RS15425	COG0366	Alpha amylase catalytic
G9H43_RS15430	COG1196	nuclear chromosome segregation
G9H43_RS15430	COG0741	lytic transglycosylase activity
G9H43_RS15430	COG0739	heme binding
G9H43_RS15435	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G9H43_RS15440	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G9H43_RS15455	COG5433	transposase activity
G9H43_RS15475	COG1032	radical SAM domain protein
G9H43_RS15485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
G9H43_RS15490	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9H43_RS15495	COG3706	GGDEF domain
G9H43_RS15500	COG1752	Esterase of the alpha-beta hydrolase superfamily
G9H43_RS15505	COG0733	neurotransmitter:sodium symporter activity
G9H43_RS15540	COG0281	malic enzyme
G9H43_RS15545	COG2207	Transcriptional regulator
G9H43_RS15550	COG0534	Mate efflux family protein
G9H43_RS15565	COG2233	PERMEase
G9H43_RS15570	COG0095	Lipoate-protein ligase
G9H43_RS15575	COG1115	amino acid carrier protein
G9H43_RS15580	COG0019	diaminopimelate decarboxylase activity
G9H43_RS15620	COG1131	(ABC) transporter
G9H43_RS15625	COG0545	Peptidyl-prolyl cis-trans isomerase
G9H43_RS15630	COG3142	Participates in the control of copper homeostasis
G9H43_RS15635	COG1940	carbohydrate kinase activity
G9H43_RS15655	COG5002	protein histidine kinase activity
G9H43_RS15660	COG0745	RESPONSE REGULATOR receiver
G9H43_RS15665	COG0346	lactoylglutathione lyase activity
G9H43_RS15670	COG3706	GGDEF domain
G9H43_RS15675	COG3284	Transcriptional regulator
G9H43_RS15685	COG1942	4-Oxalocrotonate Tautomerase
G9H43_RS15690	COG2267	carboxylic ester hydrolase activity
G9H43_RS15710	COG0697	spore germination
G9H43_RS15720	COG0667	Aldo Keto reductase
G9H43_RS15735	COG3290	protein histidine kinase activity
G9H43_RS15740	COG0281	malic enzyme
G9H43_RS15755	COG0840	transmembrane signaling receptor activity
G9H43_RS15760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS15770	COG0281	malic enzyme
G9H43_RS15790	COG0437	4 iron, 4 sulfur cluster binding
G9H43_RS15795	COG3383	formate dehydrogenase (NAD+) activity
G9H43_RS15825	COG5433	transposase activity
G9H43_RS15860	COG5433	transposase activity
G9H43_RS15880	COG0538	isocitrate dehydrogenase activity
G9H43_RS15900	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
G9H43_RS15915	COG5433	transposase activity
G9H43_RS15935	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9H43_RS15935	COG1263	PTS System
G9H43_RS15940	COG1609	Transcriptional regulator
G9H43_RS15975	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
G9H43_RS15980	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
G9H43_RS15985	COG1845	cytochrome c oxidase, subunit III
G9H43_RS15990	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
G9H43_RS15995	COG0109	protoheme IX farnesyltransferase activity
G9H43_RS16000	COG2814	Major facilitator Superfamily
G9H43_RS16055	COG0708	Exodeoxyribonuclease III
G9H43_RS16095	COG0095	Lipoate-protein ligase
G9H43_RS16145	COG1285	pathogenesis
G9H43_RS16175	COG0484	heat shock protein binding
G9H43_RS16180	COG0443	Heat shock 70 kDa protein
G9H43_RS16185	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G9H43_RS16190	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G9H43_RS16195	COG0497	DNA recombination
G9H43_RS16205	COG1227	inorganic diphosphatase activity
G9H43_RS16215	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9H43_RS16220	COG1136	(ABC) transporter
G9H43_RS16220	COG0577	efflux transmembrane transporter activity
G9H43_RS16225	COG1538	Outer membrane efflux protein
G9H43_RS16230	COG2375	cellular response to nickel ion
G9H43_RS16235	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
G9H43_RS16240	COG3328	transposase activity
G9H43_RS16245	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9H43_RS16265	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
G9H43_RS16270	COG2201	protein-glutamate methylesterase activity
G9H43_RS16275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9H43_RS16320	COG2199	diguanylate cyclase activity
G9H43_RS16320	COG2203	Gaf domain
G9H43_RS16320	COG2200	EAL domain
G9H43_RS16325	COG0826	peptidase U32
G9H43_RS16330	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G9H43_RS16335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G9H43_RS16350	COG2200	EAL domain
G9H43_RS16355	COG0737	Belongs to the 5'-nucleotidase family
G9H43_RS16375	COG2204	response regulator
G9H43_RS16380	COG0545	Peptidyl-prolyl cis-trans isomerase
G9H43_RS16395	COG1047	Peptidyl-prolyl cis-trans
G9H43_RS16400	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
G9H43_RS16410	COG0835	chemotaxis
G9H43_RS16410	COG0784	Response regulator, receiver
G9H43_RS16415	COG0429	hydrolase of the alpha beta-hydrolase fold
G9H43_RS16420	COG3706	GGDEF domain
G9H43_RS16420	COG2203	Gaf domain
G9H43_RS16420	COG4251	negative regulation of phosphorylation
G9H43_RS16420	COG5001	Diguanylate cyclase
G9H43_RS16425	COG3089	Belongs to the UPF0270 family
G9H43_RS16435	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9H43_RS16445	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9H43_RS16450	COG0463	Glycosyl transferase, family 2
G9H43_RS16460	COG0726	polysaccharide deacetylase
G9H43_RS16465	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
G9H43_RS16470	COG2076	Multidrug Resistance protein
G9H43_RS16480	COG3954	Phosphoribulokinase
G9H43_RS16495	COG1765	OsmC-like protein
G9H43_RS16510	COG3397	chitin binding
G9H43_RS16545	COG3655	Transcriptional regulator
G9H43_RS16555	COG2814	Major facilitator Superfamily
G9H43_RS16560	COG4771	TonB-dependent receptor
G9H43_RS16580	COG0748	coenzyme F420 binding
G9H43_RS16585	COG3721	Heme iron utilization protein
G9H43_RS16595	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9H43_RS16620	COG0488	(ABC) transporter
G9H43_RS16630	COG2252	PERMEase
G9H43_RS16635	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
G9H43_RS16640	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
G9H43_RS16645	COG3178	'Phosphotransferase
G9H43_RS16650	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
G9H43_RS16660	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G9H43_RS16665	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G9H43_RS16670	COG2967	ApaG domain
G9H43_RS16675	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
G9H43_RS16690	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
G9H43_RS16710	COG0318	PFAM AMP-dependent synthetase and ligase
G9H43_RS16715	COG3314	Sporulation integral membrane protein YlbJ
G9H43_RS16720	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G9H43_RS16725	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G9H43_RS16730	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G9H43_RS16735	COG0142	geranyltranstransferase activity
G9H43_RS16740	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
G9H43_RS16745	COG0330	HflC and HflK could
G9H43_RS16750	COG0330	HflC and HflK could
G9H43_RS16755	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G9H43_RS16760	COG1923	regulation of RNA biosynthetic process
G9H43_RS16765	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G9H43_RS16770	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G9H43_RS16780	COG0802	atpase or kinase
G9H43_RS16785	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
G9H43_RS16785	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G9H43_RS16805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
G9H43_RS16810	COG2011	ABC-type metal ion transport system permease component
G9H43_RS16815	COG1464	Belongs to the NlpA lipoprotein family
G9H43_RS16825	COG0840	transmembrane signaling receptor activity
G9H43_RS16835	COG4999	Histidine kinase
G9H43_RS16835	COG3850	Histidine kinase
G9H43_RS16835	COG3437	response regulator, receiver
G9H43_RS16835	COG2205	protein histidine kinase activity
G9H43_RS16850	COG2198	Histidine kinase
G9H43_RS16850	COG0784	Response regulator, receiver
G9H43_RS16850	COG5002	protein histidine kinase activity
G9H43_RS16885	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
G9H43_RS16890	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
G9H43_RS16900	COG2716	regulation of RNA biosynthetic process
G9H43_RS16905	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G9H43_RS16910	COG3013	Belongs to the UPF0304 family
G9H43_RS16920	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G9H43_RS16925	COG0857	belongs to the CobB CobQ family
G9H43_RS16925	COG0280	phosphate acetyltransferase
G9H43_RS16930	COG0440	acetolactate synthase activity
G9H43_RS16935	COG0028	Belongs to the TPP enzyme family
G9H43_RS16950	COG0671	phosphoesterase, PA-phosphatase related
G9H43_RS16960	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G9H43_RS16965	COG0473	3-isopropylmalate dehydrogenase activity
G9H43_RS16970	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G9H43_RS16975	COG0066	3-isopropylmalate dehydratase activity
G9H43_RS16990	COG4143	(ABC) transporter
G9H43_RS16995	COG1178	ABC-type Fe3 transport system permease component
G9H43_RS17000	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
G9H43_RS17005	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
G9H43_RS17015	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G9H43_RS17045	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
G9H43_RS17050	COG0564	pseudouridine synthase activity
G9H43_RS17060	COG5001	Diguanylate cyclase
G9H43_RS17060	COG3300	MHYT domain
G9H43_RS17070	COG0459	protein refolding
G9H43_RS17075	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G9H43_RS17080	COG0534	Mate efflux family protein
G9H43_RS17085	COG3030	protein affecting phage T7 exclusion by the F plasmid
G9H43_RS17090	COG1027	Aspartate ammonia-lyase
G9H43_RS17095	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G9H43_RS17105	COG0477	Major facilitator Superfamily
G9H43_RS17115	COG3227	Zinc metalloprotease (Elastase)
G9H43_RS17120	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9H43_RS17125	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9H43_RS17135	COG0673	inositol 2-dehydrogenase activity
G9H43_RS17145	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G9H43_RS17150	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G9H43_RS17155	COG3036	rescue of stalled ribosome
G9H43_RS17160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G9H43_RS17170	COG0138	bifunctional purine biosynthesis protein purh
G9H43_RS17175	COG0151	Belongs to the GarS family
G9H43_RS17215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G9H43_RS17220	COG0358	DNA primase activity
G9H43_RS17225	COG1610	YqeY-like protein
G9H43_RS17230	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G9H43_RS17235	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G9H43_RS17245	COG1388	LysM domain
G9H43_RS17245	COG4942	peptidase
G9H43_RS17250	COG1238	metal cluster binding
G9H43_RS17255	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G9H43_RS17260	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G9H43_RS17265	COG0585	pseudouridine synthase activity
G9H43_RS17275	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
G9H43_RS17280	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
G9H43_RS17285	COG0148	phosphopyruvate hydratase activity
G9H43_RS17290	COG0504	CTP synthase activity
G9H43_RS17295	COG3956	TIGRFAM MazG family protein
G9H43_RS17300	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
G9H43_RS17305	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9H43_RS17315	COG4807	Protein conserved in bacteria
G9H43_RS17320	COG3023	N-Acetylmuramoyl-L-alanine amidase
G9H43_RS17325	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
G9H43_RS17330	COG1381	Involved in DNA repair and RecF pathway recombination
G9H43_RS17340	COG0571	ribonuclease III activity
G9H43_RS17350	COG0481	GTPase activity
G9H43_RS17365	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
G9H43_RS17370	COG1595	DNA-templated transcription, initiation
G9H43_RS17375	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
G9H43_RS17425	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G9H43_RS17430	COG0191	fructose-bisphosphate aldolase activity
G9H43_RS17435	COG0126	phosphoglycerate kinase activity
G9H43_RS17440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9H43_RS17445	COG1940	carbohydrate kinase activity
G9H43_RS17470	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
G9H43_RS17480	COG1136	(ABC) transporter
G9H43_RS17540	COG5433	transposase activity
G9H43_RS17545	COG0529	Catalyzes the synthesis of activated sulfate
G9H43_RS17550	COG3273	potassium ion transport
G9H43_RS17550	COG0471	metal ion transport
G9H43_RS17555	COG2895	sulfate adenylyltransferase (ATP) activity
G9H43_RS17560	COG0175	sulfate reduction
G9H43_RS17565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9H43_RS17565	COG1648	precorrin-2 dehydrogenase activity
G9H43_RS17570	COG0330	HflC and HflK could
G9H43_RS17575	COG1585	Membrane protein implicated in regulation of membrane protease activity
G9H43_RS17580	COG0517	IMP dehydrogenase activity
G9H43_RS17580	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
G9H43_RS17585	COG0488	(ABC) transporter
G9H43_RS17595	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
G9H43_RS17630	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
G9H43_RS17635	COG1376	ErfK ybiS ycfS ynhG family protein
G9H43_RS17640	COG0668	transmembrane transport
G9H43_RS17650	COG2731	YhcH YjgK YiaL family protein
G9H43_RS17660	COG1794	racemase activity, acting on amino acids and derivatives
G9H43_RS17675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G9H43_RS17700	COG0733	neurotransmitter:sodium symporter activity
G9H43_RS17710	COG0733	neurotransmitter:sodium symporter activity
G9H43_RS17725	COG0561	phosphatase activity
G9H43_RS17760	COG1846	Transcriptional regulator
G9H43_RS17765	COG1764	response to oxidative stress
G9H43_RS17770	COG2130	NADP-dependent
G9H43_RS17790	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
G9H43_RS17795	COG1349	DNA-binding transcription factor activity
G9H43_RS17835	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS17845	COG2982	Protein involved in outer membrane biogenesis
G9H43_RS17850	COG1505	serine-type exopeptidase activity
G9H43_RS17865	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G9H43_RS17870	COG0745	RESPONSE REGULATOR receiver
G9H43_RS17875	COG2205	protein histidine kinase activity
G9H43_RS17880	COG2816	NAD+ diphosphatase activity
G9H43_RS17910	COG0316	Belongs to the HesB IscA family
G9H43_RS17920	COG0038	chloride channel
G9H43_RS17925	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G9H43_RS17940	COG0671	phosphoesterase, PA-phosphatase related
G9H43_RS17950	COG3437	response regulator, receiver
G9H43_RS17950	COG0784	Response regulator, receiver
G9H43_RS17955	COG0583	DNA-binding transcription factor activity
G9H43_RS17960	COG2076	Multidrug Resistance protein
G9H43_RS17970	COG0346	lactoylglutathione lyase activity
G9H43_RS17975	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G9H43_RS17980	COG1643	Atp-dependent helicase
G9H43_RS17990	COG1489	DNA binding
G9H43_RS17995	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
G9H43_RS18000	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G9H43_RS18005	COG0617	tRNA 3'-terminal CCA addition
G9H43_RS18010	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G9H43_RS18015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G9H43_RS18020	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G9H43_RS18030	COG0842	Transport permease protein
G9H43_RS18035	COG1131	(ABC) transporter
G9H43_RS18050	COG0163	prenyltransferase activity
G9H43_RS18055	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G9H43_RS18060	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
G9H43_RS18065	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G9H43_RS18075	COG0506	proline dehydrogenase activity
G9H43_RS18075	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G9H43_RS18075	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
G9H43_RS18080	COG4991	sh3 domain protein
G9H43_RS18085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G9H43_RS18105	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
G9H43_RS18110	COG1640	4-alpha-glucanotransferase
G9H43_RS18115	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G9H43_RS18120	COG0676	glucose-6-phosphate 1-epimerase activity
G9H43_RS18125	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
G9H43_RS18130	COG0840	transmembrane signaling receptor activity
G9H43_RS18195	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
G9H43_RS18200	COG2885	chlorophyll binding
G9H43_RS18205	COG0823	Involved in the tonB-independent uptake of proteins
G9H43_RS18220	COG0811	peptide transport
G9H43_RS18225	COG0824	Thioesterase
G9H43_RS18230	COG3790	cyd operon protein YbgE
G9H43_RS18235	COG4890	Cyd operon protein YbgT
G9H43_RS18240	COG1294	oxidase, subunit
G9H43_RS18245	COG1271	oxidase subunit
G9H43_RS18250	COG2255	four-way junction helicase activity
G9H43_RS18255	COG0632	four-way junction helicase activity
G9H43_RS18265	COG0442	prolyl-tRNA aminoacylation
G9H43_RS18275	COG1902	pentaerythritol trinitrate reductase activity
G9H43_RS18285	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G9H43_RS18315	COG0714	Associated with various cellular activities
G9H43_RS18325	COG0456	acetyltransferase
G9H43_RS18335	COG1022	Amp-dependent synthetase and ligase
G9H43_RS18345	COG2918	glutathione biosynthetic process
G9H43_RS18350	COG0612	Peptidase, M16
G9H43_RS18355	COG1238	metal cluster binding
G9H43_RS18360	COG1064	alcohol dehydrogenase
G9H43_RS18390	COG0359	binds to the 23S rRNA
G9H43_RS18395	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G9H43_RS18400	COG0360	Binds together with S18 to 16S ribosomal RNA
G9H43_RS18405	COG1914	H( )-stimulated, divalent metal cation uptake system
G9H43_RS18410	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G9H43_RS18435	COG2153	protein acetylation
G9H43_RS18445	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G9H43_RS18450	COG0557	exoribonuclease II activity
G9H43_RS18455	COG3706	GGDEF domain
G9H43_RS18460	COG1854	S-ribosylhomocysteine lyase activity
G9H43_RS18475	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G9H43_RS18475	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G9H43_RS18515	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
G9H43_RS18520	COG1047	Peptidyl-prolyl cis-trans
G9H43_RS18525	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G9H43_RS18530	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G9H43_RS18535	COG0196	riboflavin kinase activity
G9H43_RS18540	COG0728	peptidoglycan biosynthetic process
G9H43_RS18545	COG0268	Binds directly to 16S ribosomal RNA
G9H43_RS18550	COG0640	Transcriptional regulator
G9H43_RS18555	COG0583	DNA-binding transcription factor activity
G9H43_RS18560	COG4974	Belongs to the 'phage' integrase family
G9H43_RS18660	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G9H43_RS18675	COG4695	Portal protein
G9H43_RS18830	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G9H43_RS18835	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
G9H43_RS18840	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G9H43_RS18850	COG1051	belongs to the nudix hydrolase family
G9H43_RS18855	COG3066	DNA modification
G9H43_RS18865	COG0335	large ribosomal subunit rRNA binding
G9H43_RS18870	COG0336	Belongs to the RNA methyltransferase TrmD family
G9H43_RS18875	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G9H43_RS18880	COG0228	four-way junction DNA binding
G9H43_RS18885	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G9H43_RS18890	COG4137	Cytochrome C assembly protein
G9H43_RS18895	COG4536	flavin adenine dinucleotide binding
G9H43_RS18900	COG1959	2 iron, 2 sulfur cluster binding
G9H43_RS18905	COG1017	nitric oxide dioxygenase activity
G9H43_RS18905	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9H43_RS18910	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
G9H43_RS18915	COG0039	L-malate dehydrogenase activity
G9H43_RS18920	COG4160	amino acid transport
G9H43_RS18925	COG4215	(ABC) transporter
G9H43_RS18930	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS18935	COG1126	abc transporter atp-binding protein
G9H43_RS18940	COG1438	arginine binding
G9H43_RS18945	COG2837	iron assimilation
G9H43_RS18950	COG3842	ATPase activity
G9H43_RS18960	COG1840	ABC-type Fe3 transport system, periplasmic component
G9H43_RS18965	COG0347	Belongs to the P(II) protein family
G9H43_RS18980	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
G9H43_RS19000	COG1929	Belongs to the glycerate kinase type-1 family
G9H43_RS19005	COG2610	gluconate transmembrane transporter activity
G9H43_RS19010	COG3835	regulator
G9H43_RS19015	COG3112	Uncharacterised protein family (UPF0231)
G9H43_RS19030	COG0840	transmembrane signaling receptor activity
G9H43_RS19035	COG3568	Endonuclease Exonuclease Phosphatase
G9H43_RS19050	COG0513	Belongs to the DEAD box helicase family
G9H43_RS19090	COG1448	Aminotransferase
G9H43_RS19115	COG1328	CTP reductase activity
G9H43_RS19155	COG1215	transferase activity, transferring glycosyl groups
G9H43_RS19160	COG1649	PFAM Uncharacterised BCR, COG1649
G9H43_RS19160	COG0726	polysaccharide deacetylase
G9H43_RS19195	COG0840	transmembrane signaling receptor activity
G9H43_RS19200	COG3397	chitin binding
G9H43_RS19205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS19210	COG1126	abc transporter atp-binding protein
G9H43_RS19220	COG0765	amino acid transport
G9H43_RS19225	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G9H43_RS19230	COG0583	DNA-binding transcription factor activity
G9H43_RS19235	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
G9H43_RS19240	COG4208	sulfate ABC transporter
G9H43_RS19250	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
G9H43_RS19260	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
G9H43_RS19265	COG3174	membrane
G9H43_RS19270	COG0110	maltose O-acetyltransferase activity
G9H43_RS19300	COG1942	4-Oxalocrotonate Tautomerase
G9H43_RS19310	COG0583	DNA-binding transcription factor activity
G9H43_RS19315	COG0165	Argininosuccinate lyase
G9H43_RS19320	COG0137	argininosuccinate synthase activity
G9H43_RS19330	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G9H43_RS19335	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G9H43_RS19345	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
G9H43_RS19355	COG2072	flavoprotein involved in K transport
G9H43_RS19360	COG1393	Belongs to the ArsC family
G9H43_RS19365	COG0798	PFAM Bile acid sodium symporter
G9H43_RS19385	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G9H43_RS19405	COG3068	Protein conserved in bacteria
G9H43_RS19415	COG0739	heme binding
G9H43_RS19435	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
G9H43_RS19440	COG1121	(ABC) transporter
G9H43_RS19445	COG1108	ABC-type Mn2 Zn2 transport systems permease components
G9H43_RS19450	COG0583	DNA-binding transcription factor activity
G9H43_RS19460	COG1573	uracil-dna glycosylase
G9H43_RS19475	COG2827	Endonuclease containing a URI domain
G9H43_RS19495	COG0204	Acyl-transferase
G9H43_RS19515	COG3118	belongs to the thioredoxin family
G9H43_RS19520	COG2259	Doxx family
G9H43_RS19605	COG1051	belongs to the nudix hydrolase family
G9H43_RS19610	COG3150	esterase
G9H43_RS19620	COG3151	Protein conserved in bacteria
G9H43_RS19625	COG0494	nUDIX hydrolase
G9H43_RS19630	COG1538	Outer membrane efflux protein
G9H43_RS19635	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G9H43_RS19635	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G9H43_RS19640	COG1560	Kdo2-lipid A biosynthetic process
G9H43_RS19655	COG1392	Phosphate transport regulator
G9H43_RS19660	COG0306	phosphate transporter
G9H43_RS19665	COG0617	tRNA 3'-terminal CCA addition
G9H43_RS19670	COG3409	Peptidoglycan-binding domain 1 protein
G9H43_RS19670	COG3267	Type II secretory pathway component ExeA
G9H43_RS19680	COG1194	a g-specific adenine glycosylase
G9H43_RS19685	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
G9H43_RS19695	COG3111	PFAM Bacterial OB fold (BOF) protein
G9H43_RS19700	COG3240	lipase activity
G9H43_RS19715	COG3009	Protein conserved in bacteria
G9H43_RS19720	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
G9H43_RS19720	COG3008	intermembrane lipid transfer
G9H43_RS19725	COG2995	paraquat-inducible protein a
G9H43_RS19735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G9H43_RS19750	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G9H43_RS19755	COG2813	Specifically methylates the guanine in position
G9H43_RS19760	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
G9H43_RS19765	COG0297	glycogen (starch) synthase activity
G9H43_RS19800	COG1757	Na H antiporter
G9H43_RS19810	COG0110	maltose O-acetyltransferase activity
G9H43_RS19815	COG0366	Alpha amylase catalytic
G9H43_RS19820	COG1263	PTS System
G9H43_RS19820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
G9H43_RS19835	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9H43_RS19840	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9H43_RS19845	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9H43_RS19845	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
G9H43_RS19850	COG2723	6-phospho-beta-galactosidase activity
G9H43_RS19855	COG1447	Phosphotransferase system cellobiose-specific component IIA
G9H43_RS19860	COG1940	carbohydrate kinase activity
G9H43_RS19870	COG1609	Transcriptional regulator
G9H43_RS19880	COG0252	asparaginase activity
G9H43_RS19895	COG1803	Methylglyoxal synthase
G9H43_RS19920	COG1444	tRNA N-acetyltransferase activity
G9H43_RS19925	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS19930	COG0835	chemotaxis
G9H43_RS19930	COG0784	Response regulator, receiver
G9H43_RS19940	COG3314	Sporulation integral membrane protein YlbJ
G9H43_RS20075	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
G9H43_RS20080	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
G9H43_RS20100	COG0523	cobalamin synthesis protein
G9H43_RS20110	COG1280	lysine exporter protein (LysE YggA)
G9H43_RS20120	COG0583	DNA-binding transcription factor activity
G9H43_RS20125	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS20130	COG2200	EAL domain
G9H43_RS20135	COG1049	propionate catabolic process, 2-methylcitrate cycle
G9H43_RS20145	COG0840	transmembrane signaling receptor activity
G9H43_RS20150	COG0840	transmembrane signaling receptor activity
G9H43_RS20160	COG3447	MASE1 domain protein
G9H43_RS20160	COG5001	Diguanylate cyclase
G9H43_RS20160	COG5002	protein histidine kinase activity
G9H43_RS20165	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G9H43_RS20170	COG0508	dehydrogenase complex catalyzes the overall conversion of
G9H43_RS20175	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
G9H43_RS20180	COG2186	Transcriptional regulator
G9H43_RS20220	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
G9H43_RS20230	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
G9H43_RS20240	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
G9H43_RS20245	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
G9H43_RS20250	COG0494	nUDIX hydrolase
G9H43_RS20260	COG0653	protein targeting
G9H43_RS20270	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G9H43_RS20275	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G9H43_RS20280	COG0849	cell division
G9H43_RS20285	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
G9H43_RS20290	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G9H43_RS20295	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G9H43_RS20300	COG0772	Belongs to the SEDS family
G9H43_RS20305	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G9H43_RS20310	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G9H43_RS20315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G9H43_RS20325	COG0768	penicillin binding
G9H43_RS20330	COG3116	cell division
G9H43_RS20335	COG0275	rRNA processing
G9H43_RS20340	COG2001	Belongs to the MraZ family
G9H43_RS20350	COG0741	lytic transglycosylase activity
G9H43_RS20350	COG1388	LysM domain
G9H43_RS20355	COG1360	Flagellar Motor Protein
G9H43_RS20360	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
G9H43_RS20365	COG1191	sigma factor activity
G9H43_RS20390	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
G9H43_RS20425	COG1256	bacterial-type flagellum assembly
G9H43_RS20425	COG4786	Flagellar basal body rod
G9H43_RS20435	COG1706	bacterial-type flagellum-dependent cell motility
G9H43_RS20440	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
G9H43_RS20445	COG4786	Flagellar basal body rod
G9H43_RS20450	COG4786	Flagellar basal body rod
G9H43_RS20455	COG1749	Flagellar hook protein flgE
G9H43_RS20460	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
G9H43_RS20470	COG1815	bacterial-type flagellum-dependent cell motility
G9H43_RS20480	COG2747	anti-sigma28 factor FlgM
G9H43_RS20505	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
G9H43_RS20515	COG1677	Flagellar hook-basal body complex protein FliE
G9H43_RS20565	COG2197	response regulator
G9H43_RS20570	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G9H43_RS20575	COG2199	diguanylate cyclase activity
G9H43_RS20580	COG1278	Cold shock
G9H43_RS20590	COG3706	GGDEF domain
G9H43_RS20600	COG0840	transmembrane signaling receptor activity
G9H43_RS20615	COG0347	Belongs to the P(II) protein family
G9H43_RS20620	COG0004	ammonium transporteR
G9H43_RS20635	COG5433	transposase activity
G9H43_RS20645	COG0346	lactoylglutathione lyase activity
G9H43_RS20665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G9H43_RS20670	COG1074	ATP-dependent DNA helicase activity
G9H43_RS20675	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
G9H43_RS20680	COG2259	Doxx family
G9H43_RS20685	COG1741	Belongs to the pirin family
G9H43_RS20695	COG0583	DNA-binding transcription factor activity
G9H43_RS20720	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9H43_RS20730	COG3842	ATPase activity
G9H43_RS20740	COG2199	diguanylate cyclase activity
G9H43_RS20740	COG2203	Gaf domain
G9H43_RS20760	COG1247	-acetyltransferase
G9H43_RS20765	COG0753	catalase activity
G9H43_RS20790	COG0494	nUDIX hydrolase
G9H43_RS20795	COG0628	permease
G9H43_RS20800	COG3284	Transcriptional regulator
G9H43_RS20810	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
G9H43_RS20810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
G9H43_RS20810	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
G9H43_RS20815	COG1461	Dihydroxyacetone kinase
G9H43_RS20820	COG2376	Dihydroxyacetone kinase
G9H43_RS20825	COG2252	PERMEase
G9H43_RS20875	COG0203	ribosomal protein L17
G9H43_RS20880	COG0202	RNA polymerase activity
G9H43_RS20885	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G9H43_RS20890	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G9H43_RS20895	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G9H43_RS20900	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G9H43_RS20905	COG0201	protein transport
G9H43_RS20910	COG0200	Binds to the 23S rRNA
G9H43_RS20915	COG1841	ribosomal large subunit assembly
G9H43_RS20920	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G9H43_RS20925	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G9H43_RS20930	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G9H43_RS20935	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G9H43_RS20940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G9H43_RS20945	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G9H43_RS20950	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
G9H43_RS20955	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G9H43_RS20960	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G9H43_RS20965	COG0255	Belongs to the universal ribosomal protein uL29 family
G9H43_RS20970	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G9H43_RS20975	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G9H43_RS20980	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G9H43_RS20985	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G9H43_RS20990	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G9H43_RS20995	COG0089	rRNA binding
G9H43_RS21000	COG0088	Forms part of the polypeptide exit tunnel
G9H43_RS21005	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G9H43_RS21010	COG0051	transcription antitermination factor activity, RNA binding
G9H43_RS21030	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G9H43_RS21035	COG2183	response to ionizing radiation
G9H43_RS21055	COG0596	Alpha beta hydrolase
G9H43_RS21060	COG1040	competence protein
G9H43_RS21065	COG0316	Belongs to the HesB IscA family
G9H43_RS21065	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
G9H43_RS21070	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G9H43_RS21075	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
G9H43_RS21080	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9H43_RS21085	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G9H43_RS21090	COG4942	peptidase
G9H43_RS21100	COG1609	Transcriptional regulator
G9H43_RS21105	COG0800	Aldolase
G9H43_RS21110	COG0129	dihydroxy-acid dehydratase activity
G9H43_RS21115	COG3265	gluconokinase activity
G9H43_RS21120	COG2610	gluconate transmembrane transporter activity
G9H43_RS21125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G9H43_RS21130	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G9H43_RS21140	COG0456	acetyltransferase
G9H43_RS21150	COG1490	D-aminoacyl-tRNA deacylase activity
G9H43_RS21155	COG1295	ribonuclease BN
G9H43_RS21160	COG1217	gtp-binding protein TYPA
G9H43_RS21165	COG0174	glutamine synthetase
G9H43_RS21175	COG3852	Histidine kinase
G9H43_RS21180	COG2204	response regulator
G9H43_RS21185	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
G9H43_RS21190	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G9H43_RS21200	COG3078	GTPase activator activity
G9H43_RS21210	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G9H43_RS21220	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G9H43_RS21225	COG0408	coproporphyrinogen oxidase activity
G9H43_RS21230	COG0009	L-threonylcarbamoyladenylate synthase
G9H43_RS21240	COG0551	DNA topoisomerase type I activity
G9H43_RS21245	COG2922	Belongs to the Smg family
G9H43_RS21250	COG0758	DNA mediated transformation
G9H43_RS21255	COG1652	LysM domain
G9H43_RS21260	COG0242	peptide deformylase activity
G9H43_RS21265	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G9H43_RS21270	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G9H43_RS21270	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G9H43_RS21275	COG0569	domain protein
G9H43_RS21280	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9H43_RS21305	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
G9H43_RS21310	COG0686	Belongs to the AlaDH PNT family
G9H43_RS21315	COG0519	Catalyzes the synthesis of GMP from XMP
G9H43_RS21315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G9H43_RS21325	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
G9H43_RS21335	COG1012	belongs to the aldehyde dehydrogenase family
G9H43_RS21345	COG2962	Rard protein
G9H43_RS21355	COG1280	lysine exporter protein (LysE YggA)
G9H43_RS21380	COG2116	formate transmembrane transporter activity
G9H43_RS21385	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
G9H43_RS21385	COG1648	precorrin-2 dehydrogenase activity
G9H43_RS21390	COG2239	Acts as a magnesium transporter
G9H43_RS21400	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
G9H43_RS21405	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
G9H43_RS21415	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
G9H43_RS21425	COG0514	ATP-dependent DNA helicase (RecQ)
G9H43_RS21430	COG2050	protein possibly involved in aromatic compounds catabolism
G9H43_RS21445	COG2258	MOSC domain
G9H43_RS21450	COG1177	transmembrane transport
G9H43_RS21455	COG1176	ABC-type spermidine putrescine transport system, permease component I
G9H43_RS21460	COG3842	ATPase activity
G9H43_RS21480	COG0174	glutamine synthetase
G9H43_RS21500	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G9H43_RS21505	COG0443	Heat shock 70 kDa protein
G9H43_RS21520	COG0366	Alpha amylase catalytic
G9H43_RS21525	COG1086	Polysaccharide biosynthesis protein
G9H43_RS21530	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G9H43_RS21555	COG0318	PFAM AMP-dependent synthetase and ligase
G9H43_RS21575	COG1083	cytidylyl-transferase
G9H43_RS21585	COG2089	acid synthase
G9H43_RS21620	COG5433	transposase activity
G9H43_RS21630	COG4310	Domain of unknown function (DUF2172)
G9H43_RS21665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G9H43_RS21670	COG0745	RESPONSE REGULATOR receiver
G9H43_RS21675	COG2205	protein histidine kinase activity
G9H43_RS21685	COG0281	malic enzyme
G9H43_RS21690	COG0702	epimerase
G9H43_RS21695	COG0254	rRNA binding
G9H43_RS21700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G9H43_RS21710	COG1309	transcriptional regulator
G9H43_RS21730	COG0129	dihydroxy-acid dehydratase activity
G9H43_RS21740	COG3978	acetolactate synthase activity
G9H43_RS21750	COG0606	chelatase, subunit chli
G9H43_RS21760	COG1683	Conserved Protein
G9H43_RS21770	COG1335	isochorismatase
G9H43_RS21780	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
G9H43_RS21785	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
G9H43_RS21790	COG3639	organic phosphonate transmembrane transporter activity
G9H43_RS21795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
G9H43_RS21800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
G9H43_RS21810	COG3084	Protein conserved in bacteria
G9H43_RS21815	COG4251	negative regulation of phosphorylation
G9H43_RS21815	COG5001	Diguanylate cyclase
G9H43_RS21815	COG3706	GGDEF domain
G9H43_RS21815	COG2203	Gaf domain
G9H43_RS21830	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G9H43_RS21840	COG1561	YicC-like family, N-terminal region
G9H43_RS21870	COG0438	transferase activity, transferring glycosyl groups
G9H43_RS21875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
G9H43_RS21890	COG1063	alcohol dehydrogenase
G9H43_RS21905	COG0210	DNA helicase
G9H43_RS21910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G9H43_RS21915	COG2166	iron-sulfur cluster assembly
G9H43_RS21920	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
G9H43_RS21950	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
G9H43_RS21955	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
G9H43_RS21960	COG1739	Uncharacterized protein family UPF0029
G9H43_RS21970	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
G9H43_RS21975	COG1250	3-hydroxyacyl-CoA dehydrogenase
G9H43_RS21975	COG1024	Enoyl-CoA hydratase
G9H43_RS21980	COG0183	Belongs to the thiolase family
G9H43_RS22005	COG0425	Belongs to the sulfur carrier protein TusA family
G9H43_RS22010	COG0251	oxidation-reduction process
G9H43_RS22015	COG2885	chlorophyll binding
G9H43_RS22025	COG0752	glycyl-tRNA synthetase alpha subunit
G9H43_RS22030	COG0751	glycine-tRNA ligase activity
G9H43_RS22050	COG2188	Transcriptional regulator
G9H43_RS22055	COG3604	Transcriptional regulator
G9H43_RS22065	COG0446	pyridine nucleotide-disulphide oxidoreductase
G9H43_RS22075	COG0348	domain, Protein
G9H43_RS22080	COG0814	amino acid
G9H43_RS22095	COG2199	diguanylate cyclase activity
G9H43_RS22095	COG2200	EAL domain
G9H43_RS22095	COG2202	Pas domain
G9H43_RS22130	COG3328	transposase activity
G9H43_RS22165	COG1609	Transcriptional regulator
G9H43_RS22205	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
G9H43_RS22230	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
G9H43_RS22245	COG3118	belongs to the thioredoxin family
G9H43_RS22250	COG0513	Belongs to the DEAD box helicase family
G9H43_RS22255	COG0248	Ppx GppA phosphatase
G9H43_RS22265	COG0742	ribosomal rna small subunit methyltransferase
G9H43_RS22270	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
G9H43_RS22290	COG0084	hydrolase, TatD family'
G9H43_RS22295	COG0805	protein transport
G9H43_RS22300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G9H43_RS22310	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
G9H43_RS22315	COG3165	ubiquinone biosynthetic process from chorismate
G9H43_RS22325	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G9H43_RS22330	COG0402	S-adenosylhomocysteine deaminase activity
G9H43_RS22370	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
G9H43_RS22375	COG0848	biopolymer transport protein
G9H43_RS22380	COG0811	peptide transport
G9H43_RS22385	COG0811	peptide transport
G9H43_RS22395	COG2771	luxR family
G9H43_RS22400	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G9H43_RS22405	COG1349	DNA-binding transcription factor activity
G9H43_RS22410	COG0745	RESPONSE REGULATOR receiver
G9H43_RS22415	COG2205	protein histidine kinase activity
G9H43_RS22425	COG4452	Inner membrane protein CreD
G9H43_RS22430	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G9H43_RS22435	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G9H43_RS22440	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G9H43_RS22445	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G9H43_RS22450	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G9H43_RS22455	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G9H43_RS22460	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G9H43_RS22470	COG0356	it plays a direct role in the translocation of protons across the membrane
G9H43_RS22475	COG3312	ion transport
G9H43_RS22480	COG1475	DNA binding
G9H43_RS22485	COG1192	Involved in chromosome partitioning
G9H43_RS22490	COG0357	Ribosomal RNA small subunit methyltransferase G
G9H43_RS22495	COG0445	tRNA wobble uridine modification
G9H43_RS22500	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G9H43_RS22505	COG4774	siderophore transport
G9H43_RS22510	COG4615	Cyclic peptide transporter
G9H43_RS22515	COG1120	ATPase activity
G9H43_RS22520	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G9H43_RS22530	COG4774	siderophore transport
G9H43_RS22535	COG4607	ABC-type enterochelin transport system periplasmic component
G9H43_RS22540	COG4604	ABC transporter, ATP-binding protein
G9H43_RS22545	COG4605	iron ion homeostasis
G9H43_RS22550	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
G9H43_RS22555	COG1132	(ABC) transporter
G9H43_RS22560	COG1132	(ABC) transporter
G9H43_RS22560	COG2375	cellular response to nickel ion
G9H43_RS22570	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9H43_RS22580	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
G9H43_RS22595	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G9H43_RS22600	COG0706	membrane insertase activity
G9H43_RS22605	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
G9H43_RS22610	COG0594	ribonuclease P activity
G9H43_RS22615	COG0230	Belongs to the bacterial ribosomal protein bL34 family
G9H43_RS22620	COG1126	abc transporter atp-binding protein
G9H43_RS22810	COG2974	May be involved in recombination
G9H43_RS22845	COG1525	nuclease
G9H43_RS22870	COG1192	Involved in chromosome partitioning
G9H43_RS22925	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
G9H43_RS22930	COG1061	Type III restriction enzyme res subunit
G9H43_RS22935	COG1002	Type II restriction enzyme, methylase subunits
G9H43_RS22950	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
G9H43_RS23130	COG0714	Associated with various cellular activities
G9H43_RS23195	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
G9H43_RS23270	COG3409	Peptidoglycan-binding domain 1 protein
G9H43_RS23270	COG3267	Type II secretory pathway component ExeA
G9H43_RS23325	COG0778	Nitroreductase
G9H43_RS23330	COG0583	DNA-binding transcription factor activity
G9H43_RS23425	COG4974	Belongs to the 'phage' integrase family
G9H43_RS23445	COG3550	peptidyl-serine autophosphorylation
G9H43_RS23550	COG0697	spore germination
G9H43_RS23600	COG3039	Transposase
G9H43_RS23615	COG3039	Transposase
G9H43_RS23655	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
G9H43_RS23655	COG0426	domain, Protein
G9H43_RS23665	COG0840	transmembrane signaling receptor activity
G9H43_RS23680	COG1028	Short-chain dehydrogenase reductase Sdr
G9H43_RS23690	COG0583	DNA-binding transcription factor activity
G9H43_RS23700	COG3093	addiction module antidote protein HigA
G9H43_RS23745	COG3093	addiction module antidote protein HigA
G9H43_RS23780	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9H43_RS23790	COG3093	addiction module antidote protein HigA
G9H43_RS23825	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9H43_RS23835	COG3093	addiction module antidote protein HigA
G9H43_RS23870	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9H43_RS23910	COG1271	oxidase subunit
G9H43_RS23915	COG1294	oxidase, subunit
G9H43_RS23925	COG1454	alcohol dehydrogenase
G9H43_RS23985	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
G9H43_RS24025	COG1192	Involved in chromosome partitioning
G9H43_RS24075	COG2003	Belongs to the UPF0758 family
G9H43_RS24110	COG3039	Transposase
G9H43_RS24265	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
G9H43_RS24270	COG2361	Protein of unknown function DUF86
G9H43_RS24290	COG1192	Involved in chromosome partitioning
G9H43_RS24380	COG2916	Histone family protein nucleoid-structuring protein H-NS
G9H43_RS24505	COG1484	DNA-dependent DNA replication
G9H43_RS24555	COG4792	protein secretion
G9H43_RS24560	COG4791	protein targeting
G9H43_RS24565	COG4794	Type iii secretion
G9H43_RS24570	COG4790	Type iii secretion
G9H43_RS24645	COG0457	Tetratricopeptide repeat
G9H43_RS24735	COG1317	bacterial-type flagellum organization
G9H43_RS24770	COG3328	transposase activity
G9H43_RS24780	COG3706	GGDEF domain
G9H43_RS24785	COG1733	regulation of RNA biosynthetic process
G9H43_RS24860	COG0438	transferase activity, transferring glycosyl groups
G9H43_RS24915	COG0582	viral genome integration into host DNA