locus-tag	class	description
C5P03_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
C5P03_RS00010	COG0592	DNA-directed DNA polymerase activity
C5P03_RS00035	COG2378	regulation of single-species biofilm formation
C5P03_RS00040	COG0071	Belongs to the small heat shock protein (HSP20) family
C5P03_RS00045	COG0071	Belongs to the small heat shock protein (HSP20) family
C5P03_RS00060	COG3977	Valine--pyruvate aminotransferase
C5P03_RS00085	COG0745	RESPONSE REGULATOR receiver
C5P03_RS00090	COG2205	protein histidine kinase activity
C5P03_RS00115	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5P03_RS00120	COG4191	Histidine kinase
C5P03_RS00120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS00125	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_RS00130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_RS00135	COG1309	transcriptional regulator
C5P03_RS00165	COG0561	phosphatase activity
C5P03_RS00170	COG2267	carboxylic ester hydrolase activity
C5P03_RS00175	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5P03_RS00180	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5P03_RS00185	COG1758	RNA polymerase activity
C5P03_RS00190	COG0194	GDP metabolic process
C5P03_RS00200	COG0859	PFAM glycosyl transferase family 9
C5P03_RS00205	COG3642	lipopolysaccharide core region biosynthetic process
C5P03_RS00245	COG0589	response to stress
C5P03_RS00250	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5P03_RS00260	COG1528	Iron-storage protein
C5P03_RS00265	COG2081	HI0933 family
C5P03_RS00300	COG4584	PFAM Integrase catalytic
C5P03_RS00305	COG1484	DNA-dependent DNA replication
C5P03_RS00320	COG2197	response regulator
C5P03_RS00325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS00325	COG2205	protein histidine kinase activity
C5P03_RS00335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS00335	COG2205	protein histidine kinase activity
C5P03_RS00345	COG3275	phosphorelay sensor kinase activity
C5P03_RS00350	COG3279	Response regulator of the LytR AlgR family
C5P03_RS00355	COG2223	nitrite transmembrane transporter activity
C5P03_RS00360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
C5P03_RS00365	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
C5P03_RS00380	COG0583	DNA-binding transcription factor activity
C5P03_RS00385	COG4206	TonB-dependent receptor
C5P03_RS00390	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
C5P03_RS00425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
C5P03_RS00430	COG2166	iron-sulfur cluster assembly
C5P03_RS00435	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5P03_RS00440	COG0210	DNA helicase
C5P03_RS00455	COG1063	alcohol dehydrogenase
C5P03_RS00470	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
C5P03_RS00475	COG0438	transferase activity, transferring glycosyl groups
C5P03_RS00505	COG1561	YicC-like family, N-terminal region
C5P03_RS00515	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
C5P03_RS00530	COG3706	GGDEF domain
C5P03_RS00530	COG5001	Diguanylate cyclase
C5P03_RS00530	COG4251	negative regulation of phosphorylation
C5P03_RS00530	COG2203	Gaf domain
C5P03_RS00535	COG3084	Protein conserved in bacteria
C5P03_RS00545	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
C5P03_RS00550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5P03_RS00555	COG3639	organic phosphonate transmembrane transporter activity
C5P03_RS00560	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
C5P03_RS00565	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
C5P03_RS00575	COG1335	isochorismatase
C5P03_RS00585	COG1683	Conserved Protein
C5P03_RS00590	COG0204	Acyl-transferase
C5P03_RS00610	COG3978	acetolactate synthase activity
C5P03_RS00620	COG0129	dihydroxy-acid dehydratase activity
C5P03_RS00640	COG1309	transcriptional regulator
C5P03_RS00650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
C5P03_RS00655	COG0254	rRNA binding
C5P03_RS00660	COG0702	epimerase
C5P03_RS00665	COG0281	malic enzyme
C5P03_RS00675	COG2205	protein histidine kinase activity
C5P03_RS00680	COG0745	RESPONSE REGULATOR receiver
C5P03_RS00685	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5P03_RS00725	COG2089	acid synthase
C5P03_RS00735	COG1083	cytidylyl-transferase
C5P03_RS00755	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_RS00775	COG1442	glycosyl transferase family 8
C5P03_RS00795	COG1086	Polysaccharide biosynthesis protein
C5P03_RS00800	COG0366	Alpha amylase catalytic
C5P03_RS00815	COG0443	Heat shock 70 kDa protein
C5P03_RS00820	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5P03_RS00825	COG3045	CreA protein
C5P03_RS00840	COG0174	glutamine synthetase
C5P03_RS00860	COG3842	ATPase activity
C5P03_RS00865	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5P03_RS00870	COG1177	transmembrane transport
C5P03_RS00875	COG2258	MOSC domain
C5P03_RS00895	COG2050	protein possibly involved in aromatic compounds catabolism
C5P03_RS00900	COG0514	ATP-dependent DNA helicase (RecQ)
C5P03_RS00910	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
C5P03_RS00920	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
C5P03_RS00925	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C5P03_RS00935	COG2239	Acts as a magnesium transporter
C5P03_RS00940	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5P03_RS00940	COG1648	precorrin-2 dehydrogenase activity
C5P03_RS00945	COG2116	formate transmembrane transporter activity
C5P03_RS00955	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
C5P03_RS00970	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
C5P03_RS00975	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
C5P03_RS00985	COG0018	arginyl-trna synthetase
C5P03_RS00995	COG1595	DNA-templated transcription, initiation
C5P03_RS01005	COG1968	undecaprenyl-diphosphatase activity
C5P03_RS01010	COG0667	Aldo Keto reductase
C5P03_RS01015	COG2017	converts alpha-aldose to the beta-anomer
C5P03_RS01020	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5P03_RS01030	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5P03_RS01035	COG1609	Transcriptional regulator
C5P03_RS01090	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
C5P03_RS01095	COG1288	antiporter activity
C5P03_RS01100	COG1438	arginine binding
C5P03_RS01105	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
C5P03_RS01110	COG0540	Belongs to the ATCase OTCase family
C5P03_RS01125	COG0688	phosphatidylethanolamine metabolic process
C5P03_RS01135	COG3040	lipid binding
C5P03_RS01145	COG1979	alcohol dehydrogenase
C5P03_RS01150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
C5P03_RS01155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
C5P03_RS01165	COG2964	Protein conserved in bacteria
C5P03_RS01170	COG3681	Belongs to the UPF0597 family
C5P03_RS01180	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5P03_RS01185	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5P03_RS01190	COG0564	pseudouridine synthase activity
C5P03_RS01200	COG0542	response to heat
C5P03_RS01205	COG2502	aspartate--ammonia ligase
C5P03_RS01210	COG1522	sequence-specific DNA binding
C5P03_RS01225	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C5P03_RS01225	COG0617	tRNA 3'-terminal CCA addition
C5P03_RS01225	COG0517	IMP dehydrogenase activity
C5P03_RS01230	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS01245	COG2205	protein histidine kinase activity
C5P03_RS01255	COG2204	response regulator
C5P03_RS01270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
C5P03_RS01275	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
C5P03_RS01305	COG0243	molybdopterin cofactor binding
C5P03_RS01310	COG3005	denitrification pathway
C5P03_RS01315	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
C5P03_RS01320	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5P03_RS01325	COG0569	domain protein
C5P03_RS01330	COG0812	UDP-N-acetylmuramate dehydrogenase activity
C5P03_RS01355	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5P03_RS01370	COG0250	Participates in transcription elongation, termination and antitermination
C5P03_RS01375	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
C5P03_RS01380	COG0081	regulation of translation
C5P03_RS01385	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
C5P03_RS01390	COG0222	ribosome binding
C5P03_RS01395	COG0085	RNA polymerase activity
C5P03_RS01400	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
C5P03_RS01405	COG2964	Protein conserved in bacteria
C5P03_RS01420	COG2923	Belongs to the DsrF TusC family
C5P03_RS01425	COG2168	tRNA wobble position uridine thiolation
C5P03_RS01430	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
C5P03_RS01435	COG0049	tRNA binding
C5P03_RS01440	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
C5P03_RS01445	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
C5P03_RS01450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C5P03_RS01475	COG2926	Belongs to the UPF0265 family
C5P03_RS01485	COG3028	Belongs to the UPF0307 family
C5P03_RS01490	COG0312	modulator of DNA gyrase
C5P03_RS01495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
C5P03_RS01500	COG5007	Belongs to the BolA IbaG family
C5P03_RS01510	COG2854	intermembrane phospholipid transfer
C5P03_RS01515	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C5P03_RS01520	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
C5P03_RS01525	COG1127	ABC transporter
C5P03_RS01530	COG0517	IMP dehydrogenase activity
C5P03_RS01530	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C5P03_RS01535	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
C5P03_RS01540	COG3117	lipopolysaccharide transmembrane transporter activity
C5P03_RS01545	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
C5P03_RS01550	COG1137	ATPase activity
C5P03_RS01555	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
C5P03_RS01565	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS01570	COG1660	Displays ATPase and GTPase activities
C5P03_RS01575	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS01595	COG3964	amidohydrolase
C5P03_RS01630	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5P03_RS01635	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
C5P03_RS01645	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
C5P03_RS01650	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
C5P03_RS01655	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
C5P03_RS01660	COG0723	plastoquinol--plastocyanin reductase activity
C5P03_RS01665	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
C5P03_RS01670	COG2857	Cytochrome c1
C5P03_RS01675	COG0625	glutathione transferase activity
C5P03_RS01680	COG2969	positive regulation of protein catabolic process
C5P03_RS01685	COG2823	Periplasmic or secreted lipoprotein
C5P03_RS01690	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C5P03_RS01700	COG3107	peptidoglycan biosynthetic process
C5P03_RS01705	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
C5P03_RS01730	COG1987	bacterial-type flagellum assembly
C5P03_RS01755	COG1677	Flagellar hook-basal body complex protein FliE
C5P03_RS01765	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5P03_RS01790	COG2747	anti-sigma28 factor FlgM
C5P03_RS01800	COG1815	bacterial-type flagellum-dependent cell motility
C5P03_RS01815	COG1749	Flagellar hook protein flgE
C5P03_RS01820	COG4786	Flagellar basal body rod
C5P03_RS01825	COG4786	Flagellar basal body rod
C5P03_RS01830	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C5P03_RS01835	COG1706	bacterial-type flagellum-dependent cell motility
C5P03_RS01865	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5P03_RS01880	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
C5P03_RS01905	COG1191	sigma factor activity
C5P03_RS01910	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_RS01915	COG1360	Flagellar Motor Protein
C5P03_RS01925	COG0741	lytic transglycosylase activity
C5P03_RS01925	COG1388	LysM domain
C5P03_RS01935	COG2001	Belongs to the MraZ family
C5P03_RS01940	COG0275	rRNA processing
C5P03_RS01945	COG3116	cell division
C5P03_RS01950	COG0768	penicillin binding
C5P03_RS01960	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
C5P03_RS01965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5P03_RS01970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
C5P03_RS01975	COG0772	Belongs to the SEDS family
C5P03_RS01980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
C5P03_RS01985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5P03_RS01990	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
C5P03_RS01995	COG0849	cell division
C5P03_RS02000	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
C5P03_RS02005	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
C5P03_RS02015	COG0653	protein targeting
C5P03_RS02025	COG0494	nUDIX hydrolase
C5P03_RS02030	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
C5P03_RS02035	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
C5P03_RS02045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
C5P03_RS02055	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5P03_RS02080	COG2186	Transcriptional regulator
C5P03_RS02085	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
C5P03_RS02090	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5P03_RS02095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5P03_RS02100	COG5001	Diguanylate cyclase
C5P03_RS02100	COG3447	MASE1 domain protein
C5P03_RS02100	COG5002	protein histidine kinase activity
C5P03_RS02110	COG0840	transmembrane signaling receptor activity
C5P03_RS02125	COG1049	propionate catabolic process, 2-methylcitrate cycle
C5P03_RS02130	COG2200	EAL domain
C5P03_RS02135	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS02140	COG0583	DNA-binding transcription factor activity
C5P03_RS02150	COG1280	lysine exporter protein (LysE YggA)
C5P03_RS02160	COG0523	cobalamin synthesis protein
C5P03_RS02165	COG0477	Major facilitator Superfamily
C5P03_RS02180	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
C5P03_RS02185	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
C5P03_RS02295	COG3314	Sporulation integral membrane protein YlbJ
C5P03_RS02305	COG0784	Response regulator, receiver
C5P03_RS02305	COG0835	chemotaxis
C5P03_RS02310	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS02315	COG1444	tRNA N-acetyltransferase activity
C5P03_RS02340	COG1803	Methylglyoxal synthase
C5P03_RS02355	COG0252	asparaginase activity
C5P03_RS02365	COG1609	Transcriptional regulator
C5P03_RS02375	COG1940	carbohydrate kinase activity
C5P03_RS02380	COG1447	Phosphotransferase system cellobiose-specific component IIA
C5P03_RS02385	COG2723	6-phospho-beta-galactosidase activity
C5P03_RS02390	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5P03_RS02395	COG1440	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5P03_RS02400	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
C5P03_RS02420	COG0366	Alpha amylase catalytic
C5P03_RS02425	COG0110	maltose O-acetyltransferase activity
C5P03_RS02435	COG1757	Na H antiporter
C5P03_RS02475	COG0297	glycogen (starch) synthase activity
C5P03_RS02480	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C5P03_RS02485	COG2813	Specifically methylates the guanine in position
C5P03_RS02490	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
C5P03_RS02505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_RS02515	COG2995	paraquat-inducible protein a
C5P03_RS02520	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
C5P03_RS02520	COG3008	intermembrane lipid transfer
C5P03_RS02525	COG3009	Protein conserved in bacteria
C5P03_RS02540	COG3240	lipase activity
C5P03_RS02545	COG3111	PFAM Bacterial OB fold (BOF) protein
C5P03_RS02555	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
C5P03_RS02560	COG1194	a g-specific adenine glycosylase
C5P03_RS02570	COG3267	Type II secretory pathway component ExeA
C5P03_RS02570	COG3409	Peptidoglycan-binding domain 1 protein
C5P03_RS02575	COG0617	tRNA 3'-terminal CCA addition
C5P03_RS02580	COG0306	phosphate transporter
C5P03_RS02585	COG1392	Phosphate transport regulator
C5P03_RS02600	COG1560	Kdo2-lipid A biosynthetic process
C5P03_RS02605	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
C5P03_RS02605	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
C5P03_RS02610	COG1538	Outer membrane efflux protein
C5P03_RS02620	COG0494	nUDIX hydrolase
C5P03_RS02630	COG3151	Protein conserved in bacteria
C5P03_RS02640	COG3150	esterase
C5P03_RS02645	COG1051	belongs to the nudix hydrolase family
C5P03_RS02695	COG2259	Doxx family
C5P03_RS02700	COG3118	belongs to the thioredoxin family
C5P03_RS02720	COG0204	Acyl-transferase
C5P03_RS02725	COG1842	Phage shock protein A
C5P03_RS02740	COG2827	Endonuclease containing a URI domain
C5P03_RS02750	COG2962	Rard protein
C5P03_RS02755	COG1573	uracil-dna glycosylase
C5P03_RS02765	COG0583	DNA-binding transcription factor activity
C5P03_RS02770	COG1108	ABC-type Mn2 Zn2 transport systems permease components
C5P03_RS02775	COG1121	(ABC) transporter
C5P03_RS02780	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
C5P03_RS02800	COG0739	heme binding
C5P03_RS02810	COG3068	Protein conserved in bacteria
C5P03_RS02830	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
C5P03_RS02850	COG0798	PFAM Bile acid sodium symporter
C5P03_RS02855	COG1393	Belongs to the ArsC family
C5P03_RS02865	COG2072	flavoprotein involved in K transport
C5P03_RS02875	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
C5P03_RS02885	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
C5P03_RS02890	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C5P03_RS02900	COG0137	argininosuccinate synthase activity
C5P03_RS02905	COG0165	Argininosuccinate lyase
C5P03_RS02910	COG0583	DNA-binding transcription factor activity
C5P03_RS02920	COG1942	4-Oxalocrotonate Tautomerase
C5P03_RS02950	COG0110	maltose O-acetyltransferase activity
C5P03_RS02955	COG3174	membrane
C5P03_RS02960	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
C5P03_RS02970	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
C5P03_RS02975	COG4208	sulfate ABC transporter
C5P03_RS02980	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
C5P03_RS02985	COG0583	DNA-binding transcription factor activity
C5P03_RS02990	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5P03_RS02995	COG0765	amino acid transport
C5P03_RS03005	COG1126	abc transporter atp-binding protein
C5P03_RS03010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS03015	COG3397	chitin binding
C5P03_RS03020	COG0840	transmembrane signaling receptor activity
C5P03_RS03060	COG1215	transferase activity, transferring glycosyl groups
C5P03_RS03100	COG1328	CTP reductase activity
C5P03_RS03105	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C5P03_RS03120	COG1448	Aminotransferase
C5P03_RS03160	COG0513	Belongs to the DEAD box helicase family
C5P03_RS03175	COG3568	Endonuclease Exonuclease Phosphatase
C5P03_RS03180	COG0840	transmembrane signaling receptor activity
C5P03_RS03195	COG3112	Uncharacterised protein family (UPF0231)
C5P03_RS03200	COG3835	regulator
C5P03_RS03205	COG2610	gluconate transmembrane transporter activity
C5P03_RS03205	COG2610	gluconate transmembrane transporter activity
C5P03_RS03210	COG1929	Belongs to the glycerate kinase type-1 family
C5P03_RS03230	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5P03_RS03245	COG0347	Belongs to the P(II) protein family
C5P03_RS03250	COG1840	ABC-type Fe3 transport system, periplasmic component
C5P03_RS03260	COG3842	ATPase activity
C5P03_RS03265	COG2837	iron assimilation
C5P03_RS03270	COG1438	arginine binding
C5P03_RS03275	COG1126	abc transporter atp-binding protein
C5P03_RS03280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS03285	COG4215	(ABC) transporter
C5P03_RS03290	COG4160	amino acid transport
C5P03_RS03295	COG0039	L-malate dehydrogenase activity
C5P03_RS03300	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
C5P03_RS03305	COG1017	nitric oxide dioxygenase activity
C5P03_RS03305	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5P03_RS03310	COG1959	2 iron, 2 sulfur cluster binding
C5P03_RS03315	COG4536	flavin adenine dinucleotide binding
C5P03_RS03320	COG4137	Cytochrome C assembly protein
C5P03_RS03325	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
C5P03_RS03330	COG0228	four-way junction DNA binding
C5P03_RS03335	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
C5P03_RS03340	COG0336	Belongs to the RNA methyltransferase TrmD family
C5P03_RS03345	COG0335	large ribosomal subunit rRNA binding
C5P03_RS03355	COG3066	DNA modification
C5P03_RS03360	COG1051	belongs to the nudix hydrolase family
C5P03_RS03370	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
C5P03_RS03375	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
C5P03_RS03380	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C5P03_RS03390	COG0583	DNA-binding transcription factor activity
C5P03_RS03395	COG0640	Transcriptional regulator
C5P03_RS03400	COG0268	Binds directly to 16S ribosomal RNA
C5P03_RS03405	COG0728	peptidoglycan biosynthetic process
C5P03_RS03410	COG0196	riboflavin kinase activity
C5P03_RS03415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
C5P03_RS03420	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
C5P03_RS03425	COG1047	Peptidyl-prolyl cis-trans
C5P03_RS03430	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
C5P03_RS03470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5P03_RS03470	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
C5P03_RS03485	COG1854	S-ribosylhomocysteine lyase activity
C5P03_RS03490	COG3706	GGDEF domain
C5P03_RS03495	COG0557	exoribonuclease II activity
C5P03_RS03500	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
C5P03_RS03510	COG2153	protein acetylation
C5P03_RS03530	COG1914	H( )-stimulated, divalent metal cation uptake system
C5P03_RS03535	COG0360	Binds together with S18 to 16S ribosomal RNA
C5P03_RS03540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
C5P03_RS03545	COG0359	binds to the 23S rRNA
C5P03_RS03575	COG1064	alcohol dehydrogenase
C5P03_RS03580	COG1238	metal cluster binding
C5P03_RS03585	COG0612	Peptidase, M16
C5P03_RS03590	COG2918	glutathione biosynthetic process
C5P03_RS03600	COG1022	Amp-dependent synthetase and ligase
C5P03_RS03610	COG0456	acetyltransferase
C5P03_RS03620	COG0714	Associated with various cellular activities
C5P03_RS03650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
C5P03_RS03660	COG1902	pentaerythritol trinitrate reductase activity
C5P03_RS03670	COG0442	prolyl-tRNA aminoacylation
C5P03_RS03675	COG0840	transmembrane signaling receptor activity
C5P03_RS03680	COG0632	four-way junction helicase activity
C5P03_RS03685	COG2255	four-way junction helicase activity
C5P03_RS03690	COG1271	oxidase subunit
C5P03_RS03695	COG1294	oxidase, subunit
C5P03_RS03700	COG4890	Cyd operon protein YbgT
C5P03_RS03705	COG3790	cyd operon protein YbgE
C5P03_RS03710	COG0824	Thioesterase
C5P03_RS03715	COG0811	peptide transport
C5P03_RS03730	COG0823	Involved in the tonB-independent uptake of proteins
C5P03_RS03735	COG2885	chlorophyll binding
C5P03_RS03740	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
C5P03_RS03810	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
C5P03_RS03815	COG0676	glucose-6-phosphate 1-epimerase activity
C5P03_RS03820	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5P03_RS03825	COG1640	4-alpha-glucanotransferase
C5P03_RS03830	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
C5P03_RS03850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5P03_RS03855	COG4991	sh3 domain protein
C5P03_RS03860	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5P03_RS03860	COG0506	proline dehydrogenase activity
C5P03_RS03860	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
C5P03_RS03870	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
C5P03_RS03875	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
C5P03_RS03880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
C5P03_RS03885	COG0163	prenyltransferase activity
C5P03_RS03900	COG1131	(ABC) transporter
C5P03_RS03905	COG0842	Transport permease protein
C5P03_RS03915	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
C5P03_RS03920	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
C5P03_RS03925	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
C5P03_RS03930	COG0617	tRNA 3'-terminal CCA addition
C5P03_RS03935	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5P03_RS03940	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
C5P03_RS03945	COG1489	DNA binding
C5P03_RS03955	COG1643	Atp-dependent helicase
C5P03_RS03960	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5P03_RS03965	COG0346	lactoylglutathione lyase activity
C5P03_RS03975	COG2076	Multidrug Resistance protein
C5P03_RS03980	COG0583	DNA-binding transcription factor activity
C5P03_RS03985	COG0784	Response regulator, receiver
C5P03_RS03985	COG3437	response regulator, receiver
C5P03_RS03995	COG0671	phosphoesterase, PA-phosphatase related
C5P03_RS04010	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
C5P03_RS04015	COG0038	chloride channel
C5P03_RS04025	COG0316	Belongs to the HesB IscA family
C5P03_RS04055	COG1280	lysine exporter protein (LysE YggA)
C5P03_RS04060	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
C5P03_RS04075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_RS04105	COG0745	RESPONSE REGULATOR receiver
C5P03_RS04110	COG3104	oligopeptide transport
C5P03_RS04115	COG1210	Utp--glucose-1-phosphate uridylyltransferase
C5P03_RS04120	COG1555	photosystem II stabilization
C5P03_RS04130	COG2350	Protein conserved in bacteria
C5P03_RS04135	COG2917	probably involved in intracellular septation
C5P03_RS04140	COG0076	glutamate decarboxylase activity
C5P03_RS04145	COG1272	protein, Hemolysin III
C5P03_RS04150	COG2985	domain, Protein
C5P03_RS04150	COG0569	domain protein
C5P03_RS04160	COG0784	Response regulator, receiver
C5P03_RS04160	COG0835	chemotaxis
C5P03_RS04165	COG2755	lipolytic protein G-D-S-L family
C5P03_RS04170	COG4181	ATPase activity
C5P03_RS04175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
C5P03_RS04180	COG1090	epimerase
C5P03_RS04185	COG2200	EAL domain
C5P03_RS04200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
C5P03_RS04205	COG3171	Protein conserved in bacteria
C5P03_RS04210	COG2066	Belongs to the glutaminase family
C5P03_RS04215	COG2897	thiosulfate sulfurtransferase activity
C5P03_RS04225	COG1132	(ABC) transporter
C5P03_RS04240	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_RS04275	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
C5P03_RS04280	COG5001	Diguanylate cyclase
C5P03_RS04280	COG3300	MHYT domain
C5P03_RS04300	COG4628	conserved protein (DUF2132)
C5P03_RS04305	COG0688	phosphatidylethanolamine metabolic process
C5P03_RS04315	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
C5P03_RS04345	COG1278	Cold shock
C5P03_RS04355	COG0840	transmembrane signaling receptor activity
C5P03_RS04360	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5P03_RS04405	COG0848	biopolymer transport protein
C5P03_RS04410	COG0811	peptide transport
C5P03_RS04415	COG0811	peptide transport
C5P03_RS04425	COG4206	TonB-dependent receptor
C5P03_RS04435	COG4239	(ABC) transporter, permease
C5P03_RS04440	COG0747	negative chemotaxis
C5P03_RS04445	COG0444	Belongs to the ABC transporter superfamily
C5P03_RS04450	COG4608	Belongs to the ABC transporter superfamily
C5P03_RS04460	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5P03_RS04475	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
C5P03_RS04480	COG1073	alpha beta
C5P03_RS04490	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
C5P03_RS04495	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
C5P03_RS04525	COG1522	sequence-specific DNA binding
C5P03_RS04525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_RS04530	COG2313	pseudouridylate synthase activity
C5P03_RS04540	COG1858	cytochrome C peroxidase
C5P03_RS04575	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5P03_RS04580	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5P03_RS04590	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_RS04605	COG2986	histidine ammonia-lyase
C5P03_RS04630	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_RS04640	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS04645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_RS04655	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5P03_RS04665	COG2966	Psort location CytoplasmicMembrane, score
C5P03_RS04670	COG3610	response to peptide
C5P03_RS04680	COG4175	Glycine betaine
C5P03_RS04685	COG4176	ABC-type proline glycine betaine transport system permease component
C5P03_RS04690	COG2113	Glycine betaine
C5P03_RS04695	COG0175	sulfate reduction
C5P03_RS04710	COG0384	phenazine biosynthesis protein PhzF
C5P03_RS04715	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
C5P03_RS04730	COG0786	glutamate:sodium symporter activity
C5P03_RS04735	COG0252	asparaginase activity
C5P03_RS04740	COG3139	Protein of unknown function (DUF1315)
C5P03_RS04760	COG0616	signal peptide processing
C5P03_RS04765	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5P03_RS04765	COG1902	pentaerythritol trinitrate reductase activity
C5P03_RS04770	COG0778	Nitroreductase
C5P03_RS04790	COG4302	ethanolamine ammonia-lyase activity
C5P03_RS04795	COG4303	Ethanolamine ammonia lyase large subunit
C5P03_RS04805	COG2264	protein methyltransferase activity
C5P03_RS04810	COG0604	alcohol dehydrogenase
C5P03_RS04815	COG0583	DNA-binding transcription factor activity
C5P03_RS04820	COG1263	PTS System
C5P03_RS04820	COG2190	(PTS) system
C5P03_RS04820	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_RS04825	COG4145	pantothenate transmembrane transporter activity
C5P03_RS04830	COG3924	membrane
C5P03_RS04835	COG0439	Biotin carboxylase
C5P03_RS04840	COG0511	ligase activity, forming carbon-carbon bonds
C5P03_RS04845	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
C5P03_RS04850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5P03_RS04880	COG3381	protein complex oligomerization
C5P03_RS04900	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
C5P03_RS04915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
C5P03_RS04920	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5P03_RS04920	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
C5P03_RS04935	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
C5P03_RS04940	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5P03_RS04945	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
C5P03_RS04950	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
C5P03_RS04955	COG4172	Belongs to the ABC transporter superfamily
C5P03_RS04965	COG0601	transmembrane transport
C5P03_RS04975	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
C5P03_RS04980	COG0142	geranyltranstransferase activity
C5P03_RS04985	COG1722	exodeoxyribonuclease VII activity
C5P03_RS04990	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_RS05020	COG1534	Rna-binding protein
C5P03_RS05025	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
C5P03_RS05035	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
C5P03_RS05040	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
C5P03_RS05045	COG0149	triose-phosphate isomerase activity
C5P03_RS05050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
C5P03_RS05065	COG0779	Required for maturation of 30S ribosomal subunits
C5P03_RS05070	COG0195	Participates in both transcription termination and antitermination
C5P03_RS05075	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
C5P03_RS05080	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
C5P03_RS05085	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
C5P03_RS05090	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
C5P03_RS05095	COG1185	polyribonucleotide nucleotidyltransferase activity
C5P03_RS05105	COG3706	GGDEF domain
C5P03_RS05110	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
C5P03_RS05115	COG1422	Protein of unknown function (DUF1090)
C5P03_RS05170	COG0312	modulator of DNA gyrase
C5P03_RS05185	COG4974	Belongs to the 'phage' integrase family
C5P03_RS05195	COG1970	mechanosensitive ion channel activity
C5P03_RS05205	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
C5P03_RS05220	COG3545	Serine hydrolase
C5P03_RS05225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_RS05270	COG4584	PFAM Integrase catalytic
C5P03_RS05275	COG1484	DNA-dependent DNA replication
C5P03_RS05300	COG3621	Patatin-like phospholipase
C5P03_RS05315	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
C5P03_RS05320	COG0321	lipoyl(octanoyl) transferase activity
C5P03_RS05325	COG2921	Belongs to the UPF0250 family
C5P03_RS05330	COG1686	Belongs to the peptidase S11 family
C5P03_RS05335	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5P03_RS05345	COG0772	Belongs to the SEDS family
C5P03_RS05350	COG0768	penicillin binding
C5P03_RS05355	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
C5P03_RS05360	COG0799	negative regulation of ribosome biogenesis
C5P03_RS05365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
C5P03_RS05385	COG0495	leucyl-tRNA aminoacylation
C5P03_RS05390	COG2888	peptidyl-tyrosine sulfation
C5P03_RS05395	COG0815	Transfers the fatty acyl group on membrane lipoproteins
C5P03_RS05400	COG4535	Mg2 and Co2 transporter CorC
C5P03_RS05405	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
C5P03_RS05410	COG1702	phosphate starvation-inducible protein PhoH
C5P03_RS05415	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5P03_RS05420	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5P03_RS05430	COG3706	GGDEF domain
C5P03_RS05445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_RS05465	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
C5P03_RS05475	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
C5P03_RS05485	COG0516	GMP reductase activity
C5P03_RS05495	COG0642	Histidine kinase
C5P03_RS05535	COG3214	Protein conserved in bacteria
C5P03_RS05555	COG3080	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C5P03_RS05560	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
C5P03_RS05565	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
C5P03_RS05570	COG1053	succinate dehydrogenase
C5P03_RS05580	COG0584	glycerophosphoryl diester phosphodiesterase
C5P03_RS05585	COG1511	domain protein
C5P03_RS05585	COG3264	Mechanosensitive ion channel
C5P03_RS05605	COG0739	heme binding
C5P03_RS05620	COG0583	DNA-binding transcription factor activity
C5P03_RS05640	COG0583	DNA-binding transcription factor activity
C5P03_RS05645	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
C5P03_RS05675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C5P03_RS05680	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
C5P03_RS05690	COG0338	D12 class N6 adenine-specific DNA methyltransferase
C5P03_RS05695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
C5P03_RS05700	COG0546	phosphoglycolate phosphatase activity
C5P03_RS05705	COG0180	Tryptophanyl-tRNA synthetase
C5P03_RS05720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
C5P03_RS05730	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_RS05740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_RS05750	COG0674	pyruvate-flavodoxin oxidoreductase activity
C5P03_RS05750	COG1013	pyruvate-flavodoxin oxidoreductase activity
C5P03_RS05750	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_RS05750	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
C5P03_RS05760	COG0488	(ABC) transporter
C5P03_RS05775	COG0366	Alpha amylase catalytic
C5P03_RS05785	COG0443	Heat shock 70 kDa protein
C5P03_RS05815	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
C5P03_RS05825	COG0490	domain, Protein
C5P03_RS05825	COG0471	metal ion transport
C5P03_RS05895	COG0012	GTP binding
C5P03_RS05900	COG0193	aminoacyl-tRNA hydrolase activity
C5P03_RS05905	COG0737	Belongs to the 5'-nucleotidase family
C5P03_RS05910	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
C5P03_RS05920	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
C5P03_RS05925	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
C5P03_RS05930	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
C5P03_RS05935	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
C5P03_RS05940	COG2890	protein-(glutamine-N5) methyltransferase activity
C5P03_RS05960	COG1301	dicarboxylic acid transport
C5P03_RS05980	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
C5P03_RS05995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
C5P03_RS06000	COG1115	amino acid carrier protein
C5P03_RS06015	COG0714	Associated with various cellular activities
C5P03_RS06035	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
C5P03_RS06040	COG1678	Uncharacterized ACR, COG1678
C5P03_RS06050	COG0189	ligase activity
C5P03_RS06055	COG1385	rRNA (uridine-N3-)-methyltransferase activity
C5P03_RS06065	COG3091	SprT-like family
C5P03_RS06075	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
C5P03_RS06090	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
C5P03_RS06095	COG0739	heme binding
C5P03_RS06100	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5P03_RS06115	COG0463	Glycosyl transferase, family 2
C5P03_RS06130	COG2989	Protein conserved in bacteria
C5P03_RS06135	COG3108	Peptidase M15
C5P03_RS06145	COG2860	membrane
C5P03_RS06155	COG1196	nuclear chromosome segregation
C5P03_RS06160	COG3115	cell septum assembly
C5P03_RS06165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
C5P03_RS06175	COG1328	CTP reductase activity
C5P03_RS06185	COG0602	queuosine metabolic process
C5P03_RS06210	COG1566	PFAM secretion protein HlyD family protein
C5P03_RS06215	COG1846	Transcriptional regulator
C5P03_RS06230	COG0281	malic enzyme
C5P03_RS06235	COG3290	protein histidine kinase activity
C5P03_RS06265	COG0346	lactoylglutathione lyase activity
C5P03_RS06270	COG0745	RESPONSE REGULATOR receiver
C5P03_RS06275	COG5002	protein histidine kinase activity
C5P03_RS06295	COG1940	carbohydrate kinase activity
C5P03_RS06300	COG3142	Participates in the control of copper homeostasis
C5P03_RS06305	COG0545	Peptidyl-prolyl cis-trans isomerase
C5P03_RS06310	COG1131	(ABC) transporter
C5P03_RS06350	COG0019	diaminopimelate decarboxylase activity
C5P03_RS06355	COG1115	amino acid carrier protein
C5P03_RS06360	COG0095	Lipoate-protein ligase
C5P03_RS06365	COG2233	PERMEase
C5P03_RS06380	COG0534	Mate efflux family protein
C5P03_RS06385	COG2207	Transcriptional regulator
C5P03_RS06390	COG0281	malic enzyme
C5P03_RS06420	COG0733	neurotransmitter:sodium symporter activity
C5P03_RS06425	COG1752	Esterase of the alpha-beta hydrolase superfamily
C5P03_RS06430	COG3706	GGDEF domain
C5P03_RS06435	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_RS06440	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_RS06450	COG1032	radical SAM domain protein
C5P03_RS06480	COG0673	inositol 2-dehydrogenase activity
C5P03_RS06485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
C5P03_RS06490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C5P03_RS06495	COG0741	lytic transglycosylase activity
C5P03_RS06495	COG1196	nuclear chromosome segregation
C5P03_RS06495	COG0739	heme binding
C5P03_RS06500	COG0366	Alpha amylase catalytic
C5P03_RS06520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5P03_RS06530	COG0788	formyltetrahydrofolate deformylase activity
C5P03_RS06535	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5P03_RS06545	COG3118	belongs to the thioredoxin family
C5P03_RS06550	COG2091	lysine biosynthetic process via aminoadipic acid
C5P03_RS06555	COG0791	NLP P60 protein
C5P03_RS06560	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
C5P03_RS06575	COG1376	ErfK ybiS ycfS ynhG family protein
C5P03_RS06575	COG1388	LysM domain
C5P03_RS06610	COG4584	PFAM Integrase catalytic
C5P03_RS06615	COG1484	DNA-dependent DNA replication
C5P03_RS06625	COG3209	COG3209 Rhs family protein
C5P03_RS06660	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
C5P03_RS06670	COG1960	acyl-CoA dehydrogenase activity
C5P03_RS06675	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_RS06685	COG0469	pyruvate kinase activity
C5P03_RS06690	COG1737	Transcriptional regulator
C5P03_RS06715	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
C5P03_RS06735	COG1342	Belongs to the UPF0251 family
C5P03_RS06750	COG1574	metal-dependent hydrolase with the TIM-barrel fold
C5P03_RS06760	COG1677	Flagellar hook-basal body complex protein FliE
C5P03_RS06770	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
C5P03_RS06825	COG1684	flagellar biosynthetic protein fliR
C5P03_RS06835	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
C5P03_RS06860	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
C5P03_RS06865	COG2198	Histidine kinase
C5P03_RS06865	COG0784	Response regulator, receiver
C5P03_RS06865	COG0643	Histidine kinase
C5P03_RS06870	COG2201	protein-glutamate methylesterase activity
C5P03_RS06875	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_RS06880	COG1360	Flagellar Motor Protein
C5P03_RS06885	COG1192	Involved in chromosome partitioning
C5P03_RS06895	COG0835	chemotaxis
C5P03_RS06910	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5P03_RS06915	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5P03_RS06920	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
C5P03_RS06925	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
C5P03_RS06930	COG1138	Cytochrome C-type biogenesis protein
C5P03_RS06935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
C5P03_RS06940	COG3088	subunit of a heme lyase
C5P03_RS06940	COG4235	cytochrome complex assembly
C5P03_RS06960	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
C5P03_RS06965	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5P03_RS06965	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5P03_RS06980	COG0259	pyridoxamine-phosphate oxidase activity
C5P03_RS06985	COG0625	glutathione transferase activity
C5P03_RS06995	COG3153	acetyltransferase
C5P03_RS07015	COG2850	peptidyl-arginine hydroxylation
C5P03_RS07020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
C5P03_RS07025	COG2915	High frequency lysogenization protein hflD homolog
C5P03_RS07030	COG0482	sulfurtransferase activity
C5P03_RS07050	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_RS07060	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_RS07060	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_RS07060	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS07090	COG0159	tryptophan synthase activity
C5P03_RS07095	COG0133	tryptophan synthase activity
C5P03_RS07100	COG0134	indole-3-glycerol-phosphate synthase activity
C5P03_RS07100	COG0135	phosphoribosylanthranilate isomerase activity
C5P03_RS07105	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C5P03_RS07110	COG0512	Glutamine amidotransferase of anthranilate synthase
C5P03_RS07110	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
C5P03_RS07115	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5P03_RS07125	COG0009	L-threonylcarbamoyladenylate synthase
C5P03_RS07135	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
C5P03_RS07145	COG1946	Acyl-CoA thioesterase
C5P03_RS07160	COG1309	transcriptional regulator
C5P03_RS07165	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_RS07170	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_RS07190	COG1091	dTDP-4-dehydrorhamnose reductase activity
C5P03_RS07210	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5P03_RS07215	COG1459	type II secretion system
C5P03_RS07250	COG1450	Type ii and iii secretion system protein
C5P03_RS07270	COG0438	transferase activity, transferring glycosyl groups
C5P03_RS07275	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
C5P03_RS07295	COG3273	potassium ion transport
C5P03_RS07295	COG0471	metal ion transport
C5P03_RS07300	COG0471	metal ion transport
C5P03_RS07300	COG0490	domain, Protein
C5P03_RS07320	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
C5P03_RS07350	COG0438	transferase activity, transferring glycosyl groups
C5P03_RS07360	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
C5P03_RS07370	COG3132	Protein of unknown function, DUF480
C5P03_RS07385	COG4584	PFAM Integrase catalytic
C5P03_RS07390	COG1484	DNA-dependent DNA replication
C5P03_RS07430	COG1278	Cold shock
C5P03_RS07485	COG4166	transmembrane transport
C5P03_RS07490	COG0622	Phosphoesterase
C5P03_RS07510	COG0784	Response regulator, receiver
C5P03_RS07510	COG0835	chemotaxis
C5P03_RS07515	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
C5P03_RS07520	COG1815	bacterial-type flagellum-dependent cell motility
C5P03_RS07540	COG4787	bacterial-type flagellum-dependent cell motility
C5P03_RS07550	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
C5P03_RS07555	COG1706	bacterial-type flagellum-dependent cell motility
C5P03_RS07575	COG2239	Acts as a magnesium transporter
C5P03_RS07580	COG0248	Ppx GppA phosphatase
C5P03_RS07585	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
C5P03_RS07615	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
C5P03_RS07620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
C5P03_RS07625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
C5P03_RS07630	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
C5P03_RS07650	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
C5P03_RS07660	COG0590	tRNA wobble adenosine to inosine editing
C5P03_RS07665	COG0573	inorganic phosphate transmembrane transporter activity
C5P03_RS07670	COG0581	inorganic phosphate transmembrane transporter activity
C5P03_RS07675	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
C5P03_RS07680	COG0704	Plays a role in the regulation of phosphate uptake
C5P03_RS07685	COG1253	flavin adenine dinucleotide binding
C5P03_RS07700	COG0531	amino acid
C5P03_RS07710	COG1126	abc transporter atp-binding protein
C5P03_RS07715	COG0765	amino acid transport
C5P03_RS07720	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS07725	COG3706	GGDEF domain
C5P03_RS07730	COG2271	Major facilitator Superfamily
C5P03_RS07745	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5P03_RS07765	COG1785	Belongs to the alkaline phosphatase family
C5P03_RS07770	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
C5P03_RS07775	COG0123	including yeast histone deacetylase and acetoin utilization protein
C5P03_RS07785	COG1199	ATP-dependent helicase activity
C5P03_RS07800	COG1448	Aminotransferase
C5P03_RS07805	COG0433	COG0433 Predicted ATPase
C5P03_RS07820	COG2333	competence protein COMEC
C5P03_RS07820	COG0658	competence protein
C5P03_RS07825	COG1132	(ABC) transporter
C5P03_RS07830	COG1663	tetraacyldisaccharide 4'-kinase activity
C5P03_RS07835	COG2835	tetraacyldisaccharide 4'-kinase activity
C5P03_RS07840	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
C5P03_RS07845	COG2197	response regulator
C5P03_RS07850	COG0322	excinuclease ABC activity
C5P03_RS07875	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
C5P03_RS08015	COG4695	Portal protein
C5P03_RS08070	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C5P03_RS08080	COG4974	Belongs to the 'phage' integrase family
C5P03_RS08110	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_RS08120	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5P03_RS08185	COG2119	membrane
C5P03_RS08230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS08230	COG2205	protein histidine kinase activity
C5P03_RS08240	COG4138	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system
C5P03_RS08245	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_RS08250	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
C5P03_RS08255	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5P03_RS08260	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
C5P03_RS08265	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
C5P03_RS08280	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
C5P03_RS08285	COG0505	Belongs to the CarA family
C5P03_RS08290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
C5P03_RS08295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5P03_RS08330	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_RS08335	COG0513	Belongs to the DEAD box helicase family
C5P03_RS08360	COG0789	Transcriptional regulator
C5P03_RS08375	COG0493	'glutamate synthase
C5P03_RS08380	COG0069	glutamate synthase activity
C5P03_RS08380	COG0067	glutamate synthase
C5P03_RS08380	COG0070	glutamate synthase
C5P03_RS08385	COG1242	4 iron, 4 sulfur cluster binding
C5P03_RS08455	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
C5P03_RS08460	COG1288	antiporter activity
C5P03_RS08465	COG0436	Aminotransferase
C5P03_RS08475	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
C5P03_RS08480	COG2027	D-alanyl-D-alanine carboxypeptidase
C5P03_RS08485	COG1061	Type III restriction enzyme res subunit
C5P03_RS08490	COG1566	PFAM secretion protein HlyD family protein
C5P03_RS08500	COG1966	Carbon starvation protein
C5P03_RS08505	COG3279	Response regulator of the LytR AlgR family
C5P03_RS08510	COG3275	phosphorelay sensor kinase activity
C5P03_RS08520	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_RS08520	COG1454	alcohol dehydrogenase
C5P03_RS08530	COG2095	MarC family integral membrane protein
C5P03_RS08540	COG0601	transmembrane transport
C5P03_RS08545	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_RS08550	COG0444	Belongs to the ABC transporter superfamily
C5P03_RS08565	COG0861	Integral membrane protein TerC family
C5P03_RS08570	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5P03_RS08580	COG1301	dicarboxylic acid transport
C5P03_RS08595	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
C5P03_RS08610	COG0537	adenosine 5'-monophosphoramidase activity
C5P03_RS08645	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_RS08650	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_RS08670	COG1007	ATP synthesis coupled electron transport
C5P03_RS08675	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_RS08685	COG0713	ATP synthesis coupled electron transport
C5P03_RS08690	COG0839	Belongs to the complex I subunit 6 family
C5P03_RS08695	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_RS08700	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
C5P03_RS08705	COG1034	ATP synthesis coupled electron transport
C5P03_RS08720	COG0649	NAD binding
C5P03_RS08720	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_RS08725	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_RS08730	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_RS08735	COG1360	Flagellar Motor Protein
C5P03_RS08740	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
C5P03_RS08755	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
C5P03_RS08770	COG4597	amino acid ABC transporter
C5P03_RS08775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS08780	COG0765	amino acid transport
C5P03_RS08785	COG1126	abc transporter atp-binding protein
C5P03_RS08795	COG0724	RNA recognition motif
C5P03_RS08800	COG4989	oxidoreductase activity
C5P03_RS08825	COG3437	response regulator, receiver
C5P03_RS08830	COG0583	DNA-binding transcription factor activity
C5P03_RS08865	COG2814	Major facilitator Superfamily
C5P03_RS08870	COG0583	DNA-binding transcription factor activity
C5P03_RS08880	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
C5P03_RS08885	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
C5P03_RS08890	COG0539	negative regulation of cytoplasmic translation
C5P03_RS08895	COG0776	regulation of translation
C5P03_RS08905	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
C5P03_RS08910	COG0284	orotidine-5'-phosphate decarboxylase activity
C5P03_RS08925	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
C5P03_RS08930	COG0602	queuosine metabolic process
C5P03_RS08935	COG3530	Putative quorum-sensing-regulated virulence factor
C5P03_RS08940	COG2096	Adenosyltransferase
C5P03_RS08945	COG2916	Histone family protein nucleoid-structuring protein H-NS
C5P03_RS08955	COG1757	Na H antiporter
C5P03_RS08960	COG1435	thymidine kinase activity
C5P03_RS08985	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5P03_RS08990	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
C5P03_RS08995	COG0437	4 iron, 4 sulfur cluster binding
C5P03_RS09000	COG5557	Pfam Polysulphide reductase, NrfD
C5P03_RS09005	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
C5P03_RS09010	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C5P03_RS09015	COG1773	rubredoxin
C5P03_RS09025	COG0601	transmembrane transport
C5P03_RS09030	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_RS09045	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
C5P03_RS09050	COG0375	protein maturation
C5P03_RS09055	COG0309	Hydrogenase expression formation protein (HypE)
C5P03_RS09065	COG0298	carbon dioxide binding
C5P03_RS09070	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
C5P03_RS09080	COG1921	L-seryl-tRNASec selenium transferase activity
C5P03_RS09085	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
C5P03_RS09095	COG3260	NADH ubiquinone oxidoreductase 20
C5P03_RS09100	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
C5P03_RS09105	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
C5P03_RS09105	COG3261	NADH dehydrogenase
C5P03_RS09110	COG0650	Formate hydrogenlyase subunit 4
C5P03_RS09115	COG0651	ATP synthesis coupled electron transport
C5P03_RS09120	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_RS09125	COG3158	transport of potassium into the cell
C5P03_RS09145	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_RS09170	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
C5P03_RS09175	COG0326	Molecular chaperone. Has ATPase activity
C5P03_RS09185	COG0563	adenylate kinase activity
C5P03_RS09190	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
C5P03_RS09195	COG3788	relative of glutathione S-transferase, MAPEG superfamily
C5P03_RS09200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_RS09205	COG0840	transmembrane signaling receptor activity
C5P03_RS09220	COG3300	MHYT domain
C5P03_RS09220	COG5001	Diguanylate cyclase
C5P03_RS09225	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
C5P03_RS09245	COG1021	2,3-dihydroxybenzoate-AMP ligase
C5P03_RS09250	COG3433	isochorismatase activity
C5P03_RS09250	COG1535	isochorismatase
C5P03_RS09255	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_RS09260	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS09270	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_RS09270	COG0300	oxidoreductase activity
C5P03_RS09270	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_RS09270	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS09270	COG3321	synthase
C5P03_RS09275	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5P03_RS09280	COG2977	Belongs to the P-Pant transferase superfamily
C5P03_RS09285	COG1120	ATPase activity
C5P03_RS09290	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_RS09295	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_RS09300	COG4771	TonB-dependent receptor
C5P03_RS09325	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
C5P03_RS09325	COG0644	oxidoreductase
C5P03_RS09345	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
C5P03_RS09350	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
C5P03_RS09355	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_RS09370	COG1570	exodeoxyribonuclease VII activity
C5P03_RS09375	COG3038	cytochrome b561
C5P03_RS09395	COG0516	GMP reductase activity
C5P03_RS09395	COG0517	IMP dehydrogenase activity
C5P03_RS09400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5P03_RS09400	COG0519	Catalyzes the synthesis of GMP from XMP
C5P03_RS09435	COG1025	Belongs to the peptidase M16 family
C5P03_RS09440	COG2062	phosphohistidine phosphatase, SixA
C5P03_RS09450	COG0697	spore germination
C5P03_RS09455	COG4166	transmembrane transport
C5P03_RS09460	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
C5P03_RS09465	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
C5P03_RS09475	COG4591	ABC-type transport system involved in lipoprotein release permease component
C5P03_RS09480	COG1136	(ABC) transporter
C5P03_RS09485	COG4591	ABC-type transport system involved in lipoprotein release permease component
C5P03_RS09490	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
C5P03_RS09505	COG0544	peptidyl-prolyl cis-trans isomerase activity
C5P03_RS09510	COG0740	serine-type endopeptidase activity
C5P03_RS09515	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
C5P03_RS09520	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
C5P03_RS09525	COG0776	regulation of translation
C5P03_RS09530	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5P03_RS09535	COG0488	(ABC) transporter
C5P03_RS09540	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5P03_RS09545	COG3162	membrane
C5P03_RS09560	COG1024	Enoyl-CoA hydratase
C5P03_RS09560	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5P03_RS09565	COG1115	amino acid carrier protein
C5P03_RS09570	COG0456	acetyltransferase
C5P03_RS09580	COG1584	GPR1 FUN34 yaaH family protein
C5P03_RS09610	COG1024	Enoyl-CoA hydratase
C5P03_RS09615	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
C5P03_RS09620	COG1960	acyl-CoA dehydrogenase activity
C5P03_RS09630	COG1960	acyl-CoA dehydrogenase activity
C5P03_RS09635	COG1024	Enoyl-CoA hydratase
C5P03_RS09640	COG1024	Enoyl-CoA hydratase
C5P03_RS09650	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS09660	COG0730	response to heat
C5P03_RS09705	COG3706	GGDEF domain
C5P03_RS09710	COG2840	Smr protein MutS2
C5P03_RS09715	COG2890	protein-(glutamine-N5) methyltransferase activity
C5P03_RS09720	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
C5P03_RS09730	COG0513	Belongs to the DEAD box helicase family
C5P03_RS09735	COG5654	RES domain protein
C5P03_RS09745	COG0814	amino acid
C5P03_RS09750	COG1609	Transcriptional regulator
C5P03_RS09755	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS09755	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS09760	COG1105	Belongs to the carbohydrate kinase PfkB family
C5P03_RS09765	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_RS09765	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
C5P03_RS09765	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
C5P03_RS09770	COG3313	Fe-S protein
C5P03_RS09775	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
C5P03_RS09780	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
C5P03_RS09785	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5P03_RS09790	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5P03_RS09800	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5P03_RS09820	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
C5P03_RS09825	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
C5P03_RS09830	COG0291	Belongs to the bacterial ribosomal protein bL35 family
C5P03_RS09835	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
C5P03_RS09840	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
C5P03_RS09845	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_RS09845	COG0072	phenylalanine-tRNA ligase activity
C5P03_RS09850	COG0776	regulation of translation
C5P03_RS09880	COG2199	diguanylate cyclase activity
C5P03_RS09885	COG1609	Transcriptional regulator
C5P03_RS09890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_RS09895	COG1879	ABC-type sugar transport system periplasmic component
C5P03_RS09900	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5P03_RS09910	COG1869	D-ribose catabolic process
C5P03_RS09915	COG0625	glutathione transferase activity
C5P03_RS09930	COG0037	tRNA processing
C5P03_RS09935	COG0589	response to stress
C5P03_RS09940	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
C5P03_RS09955	COG2217	Heavy metal translocating P-type atpase
C5P03_RS09965	COG2010	Cytochrome c
C5P03_RS09980	COG3278	Belongs to the heme-copper respiratory oxidase family
C5P03_RS09990	COG1956	GAF domain-containing protein
C5P03_RS09995	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
C5P03_RS10005	COG0308	aminopeptidase N
C5P03_RS10015	COG2902	Dehydrogenase
C5P03_RS10020	COG0167	dihydroorotate dehydrogenase activity
C5P03_RS10030	COG0116	Belongs to the methyltransferase superfamily
C5P03_RS10030	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C5P03_RS10040	COG0488	(ABC) transporter
C5P03_RS10055	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5P03_RS10060	COG1067	ATP-dependent peptidase activity
C5P03_RS10070	COG4128	Pfam Zonular occludens toxin
C5P03_RS10125	COG1484	DNA-dependent DNA replication
C5P03_RS10130	COG4584	PFAM Integrase catalytic
C5P03_RS10135	COG4128	Pfam Zonular occludens toxin
C5P03_RS10205	COG4221	oxidoreductase activity
C5P03_RS10255	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
C5P03_RS10265	COG2995	paraquat-inducible protein a
C5P03_RS10275	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
C5P03_RS10275	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5P03_RS10290	COG0084	hydrolase, TatD family'
C5P03_RS10295	COG0470	DNA polymerase III
C5P03_RS10300	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
C5P03_RS10305	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
C5P03_RS10310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
C5P03_RS10315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_RS10320	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
C5P03_RS10325	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS10335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5P03_RS10340	COG0416	fatty acid biosynthetic process
C5P03_RS10345	COG0333	Belongs to the bacterial ribosomal protein bL32 family
C5P03_RS10350	COG1399	metal-binding, possibly nucleic acid-binding protein
C5P03_RS10360	COG0546	phosphoglycolate phosphatase activity
C5P03_RS10370	COG1530	ribonuclease E activity
C5P03_RS10380	COG0306	phosphate transporter
C5P03_RS10385	COG0717	Belongs to the dCTP deaminase family
C5P03_RS10390	COG0572	uridine kinase
C5P03_RS10395	COG0489	protein tyrosine kinase activity
C5P03_RS10400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_RS10400	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_RS10410	COG1254	Belongs to the acylphosphatase family
C5P03_RS10420	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
C5P03_RS10435	COG0709	Synthesizes selenophosphate from selenide and ATP
C5P03_RS10440	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
C5P03_RS10445	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5P03_RS10450	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
C5P03_RS10460	COG1643	Atp-dependent helicase
C5P03_RS10465	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
C5P03_RS10465	COG0617	tRNA 3'-terminal CCA addition
C5P03_RS10465	COG0517	IMP dehydrogenase activity
C5P03_RS10470	COG2197	response regulator
C5P03_RS10475	COG3314	Sporulation integral membrane protein YlbJ
C5P03_RS10480	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
C5P03_RS10485	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
C5P03_RS10490	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
C5P03_RS10495	COG2832	Protein of unknown function (DUF454)
C5P03_RS10500	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5P03_RS10520	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_RS10525	COG2267	carboxylic ester hydrolase activity
C5P03_RS10535	COG1214	PFAM Peptidase M22, glycoprotease
C5P03_RS10540	COG1199	ATP-dependent helicase activity
C5P03_RS10550	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
C5P03_RS10555	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
C5P03_RS10560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
C5P03_RS10565	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
C5P03_RS10565	COG0131	Imidazoleglycerol-phosphate dehydratase
C5P03_RS10570	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
C5P03_RS10575	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
C5P03_RS10580	COG3437	response regulator, receiver
C5P03_RS10585	COG2199	diguanylate cyclase activity
C5P03_RS10590	COG0784	Response regulator, receiver
C5P03_RS10590	COG2198	Histidine kinase
C5P03_RS10590	COG2205	protein histidine kinase activity
C5P03_RS10595	COG0107	imidazoleglycerol-phosphate synthase activity
C5P03_RS10600	COG0140	phosphoribosyl-ATP diphosphatase activity
C5P03_RS10600	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
C5P03_RS10610	COG2378	regulation of single-species biofilm formation
C5P03_RS10670	COG2823	Periplasmic or secreted lipoprotein
C5P03_RS10675	COG2203	Gaf domain
C5P03_RS10675	COG3706	GGDEF domain
C5P03_RS10675	COG4251	negative regulation of phosphorylation
C5P03_RS10675	COG5001	Diguanylate cyclase
C5P03_RS10680	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5P03_RS10690	COG1129	ABC transporter
C5P03_RS10695	COG1879	ABC-type sugar transport system periplasmic component
C5P03_RS10715	COG2824	Alkylphosphonate utilization operon protein PhnA
C5P03_RS10720	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5P03_RS10720	COG1024	Enoyl-CoA hydratase
C5P03_RS10725	COG0183	Belongs to the thiolase family
C5P03_RS10730	COG0714	Associated with various cellular activities
C5P03_RS10770	COG2067	long-chain fatty acid transport protein
C5P03_RS10775	COG2067	long-chain fatty acid transport protein
C5P03_RS10780	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
C5P03_RS10800	COG3123	guanosine phosphorylase activity
C5P03_RS10805	COG1760	l-serine dehydratase
C5P03_RS10815	COG1760	l-serine dehydratase
C5P03_RS10820	COG2951	lytic endotransglycosylase activity
C5P03_RS10825	COG3100	YcgL domain-containing protein
C5P03_RS10830	COG0850	regulation of cytokinetic process
C5P03_RS10835	COG2894	cell division
C5P03_RS10840	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
C5P03_RS10845	COG3099	Belongs to the UPF0263 family
C5P03_RS10850	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
C5P03_RS10890	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
C5P03_RS10895	COG0697	spore germination
C5P03_RS10900	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
C5P03_RS10905	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
C5P03_RS10915	COG0307	riboflavin synthase, alpha
C5P03_RS10925	COG0534	Mate efflux family protein
C5P03_RS10950	COG0417	DNA replication proofreading
C5P03_RS10975	COG1560	Kdo2-lipid A biosynthetic process
C5P03_RS10980	COG1560	Kdo2-lipid A biosynthetic process
C5P03_RS10990	COG0583	DNA-binding transcription factor activity
C5P03_RS10995	COG0673	inositol 2-dehydrogenase activity
C5P03_RS11000	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
C5P03_RS11005	COG0583	DNA-binding transcription factor activity
C5P03_RS11010	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS11030	COG3134	Outer membrane lipoprotein
C5P03_RS11050	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_RS11070	COG4681	YaeQ
C5P03_RS11140	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
C5P03_RS11145	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
C5P03_RS11150	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
C5P03_RS11160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
C5P03_RS11165	COG1434	Gram-negative-bacterium-type cell wall biogenesis
C5P03_RS11175	COG0205	6-phosphofructokinase activity
C5P03_RS11220	COG1011	Hydrolase
C5P03_RS11225	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5P03_RS11280	COG3593	DNA synthesis involved in DNA repair
C5P03_RS11295	COG0583	DNA-binding transcription factor activity
C5P03_RS11300	COG0730	response to heat
C5P03_RS11305	COG3148	PFAM DTW domain containing protein
C5P03_RS11315	COG1181	Belongs to the D-alanine--D-alanine ligase family
C5P03_RS11325	COG0386	Belongs to the glutathione peroxidase family
C5P03_RS11330	COG0513	Belongs to the DEAD box helicase family
C5P03_RS11345	COG1742	UPF0060 membrane protein
C5P03_RS11380	COG2329	Antibiotic biosynthesis monooxygenase
C5P03_RS11385	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C5P03_RS11405	COG3243	poly(R)-hydroxyalkanoic acid synthase
C5P03_RS11415	COG2501	S4 domain
C5P03_RS11425	COG1132	(ABC) transporter
C5P03_RS11440	COG3118	belongs to the thioredoxin family
C5P03_RS11445	COG0471	metal ion transport
C5P03_RS11450	COG0058	SHG alpha-glucan phosphorylase activity
C5P03_RS11480	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
C5P03_RS11490	COG0814	amino acid
C5P03_RS11495	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
C5P03_RS11500	COG0514	ATP-dependent DNA helicase (RecQ)
C5P03_RS11505	COG2766	serine protein kinase
C5P03_RS11515	COG2719	SpoVR family
C5P03_RS11520	COG2186	Transcriptional regulator
C5P03_RS11525	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C5P03_RS11530	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
C5P03_RS11535	COG0586	Pfam SNARE associated Golgi protein
C5P03_RS11545	COG0556	nucleotide-excision repair
C5P03_RS11560	COG2985	domain, Protein
C5P03_RS11560	COG0569	domain protein
C5P03_RS11565	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C5P03_RS11585	COG4565	transcriptional regulatory protein
C5P03_RS11590	COG3290	protein histidine kinase activity
C5P03_RS11595	COG1846	Transcriptional regulator
C5P03_RS11595	COG1940	carbohydrate kinase activity
C5P03_RS11600	COG0840	transmembrane signaling receptor activity
C5P03_RS11605	COG3012	SEC-C Motif Domain Protein
C5P03_RS11610	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C5P03_RS11615	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
C5P03_RS11620	COG0247	lactate metabolic process
C5P03_RS11630	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
C5P03_RS11635	COG0437	4 iron, 4 sulfur cluster binding
C5P03_RS11640	COG3301	Polysulphide reductase, NrfD
C5P03_RS11655	COG3088	subunit of a heme lyase
C5P03_RS11655	COG4235	cytochrome complex assembly
C5P03_RS11670	COG3033	Beta-eliminating lyase
C5P03_RS11680	COG3046	protein related to deoxyribodipyrimidine photolyase
C5P03_RS11685	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_RS11710	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
C5P03_RS11715	COG0583	DNA-binding transcription factor activity
C5P03_RS11725	COG4774	siderophore transport
C5P03_RS11730	COG2207	Transcriptional regulator
C5P03_RS11730	COG3708	Transcriptional regulator
C5P03_RS11740	COG0583	DNA-binding transcription factor activity
C5P03_RS11745	COG2910	NAD(P)H-binding
C5P03_RS11760	COG0612	Peptidase, M16
C5P03_RS11765	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C5P03_RS11770	COG1944	ATP diphosphatase activity
C5P03_RS11775	COG2116	formate transmembrane transporter activity
C5P03_RS11780	COG1882	Formate acetyltransferase
C5P03_RS11785	COG2983	Belongs to the UPF0260 family
C5P03_RS11790	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
C5P03_RS11795	COG0045	succinate-CoA ligase (ADP-forming) activity
C5P03_RS11800	COG0508	dehydrogenase complex catalyzes the overall conversion of
C5P03_RS11805	COG0567	Dehydrogenase, E1 component
C5P03_RS11815	COG1053	succinate dehydrogenase
C5P03_RS11820	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
C5P03_RS11845	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
C5P03_RS11850	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
C5P03_RS11850	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_RS11860	COG3069	C4-dicarboxylate transmembrane transporter activity
C5P03_RS11875	COG1451	nucleotide metabolic process
C5P03_RS11890	COG0254	rRNA binding
C5P03_RS11895	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5P03_RS11900	COG0469	pyruvate kinase activity
C5P03_RS11910	COG1874	Beta-galactosidase
C5P03_RS11915	COG3867	Arabinogalactan endo-beta-1,4-galactanase
C5P03_RS11920	COG3833	ABC-type maltose transport systems, permease component
C5P03_RS11925	COG1175	transmembrane transport
C5P03_RS11930	COG2182	Extracellular solute-binding protein
C5P03_RS11970	COG4580	involved in the transport of maltose and maltodextrins
C5P03_RS11980	COG1609	Transcriptional regulator
C5P03_RS11985	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5P03_RS11990	COG1085	galactose-1-phosphate uridylyltransferase
C5P03_RS11995	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
C5P03_RS12005	COG1172	Belongs to the binding-protein-dependent transport system permease family
C5P03_RS12010	COG1129	ABC transporter
C5P03_RS12015	COG1879	ABC-type sugar transport system periplasmic component
C5P03_RS12020	COG1069	ribulokinase activity
C5P03_RS12030	COG2160	L-arabinose isomerase activity
C5P03_RS12035	COG0583	DNA-binding transcription factor activity
C5P03_RS12045	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5P03_RS12060	COG2925	Exonuclease
C5P03_RS12075	COG1380	Effector of murein hydrolase LrgA
C5P03_RS12080	COG1346	cytolysis
C5P03_RS12085	COG0295	cytidine deaminase activity
C5P03_RS12090	COG1022	Amp-dependent synthetase and ligase
C5P03_RS12105	COG0861	Integral membrane protein TerC family
C5P03_RS12115	COG2199	diguanylate cyclase activity
C5P03_RS12130	COG2154	pterin-4-alpha-carbinolamine dehydratase
C5P03_RS12140	COG3768	UPF0283 membrane protein
C5P03_RS12145	COG3106	COG3106 Predicted ATPase
C5P03_RS12160	COG1842	Phage shock protein A
C5P03_RS12165	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
C5P03_RS12175	COG4168	peptide transport system, permease
C5P03_RS12180	COG4171	peptide transport system, permease
C5P03_RS12185	COG4172	Belongs to the ABC transporter superfamily
C5P03_RS12190	COG4172	Belongs to the ABC transporter superfamily
C5P03_RS12200	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
C5P03_RS12205	COG1286	toxin biosynthetic process
C5P03_RS12210	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
C5P03_RS12215	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
C5P03_RS12220	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
C5P03_RS12225	COG1674	ftsk spoiiie
C5P03_RS12225	COG0531	amino acid
C5P03_RS12245	COG0492	ferredoxin-NADP+ reductase activity
C5P03_RS12250	COG3706	GGDEF domain
C5P03_RS12255	COG3134	Outer membrane lipoprotein
C5P03_RS12260	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
C5P03_RS12265	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
C5P03_RS12270	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
C5P03_RS12275	COG0542	response to heat
C5P03_RS12280	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
C5P03_RS12285	COG1278	Cold shock
C5P03_RS12290	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
C5P03_RS12350	COG3829	transcription factor binding
C5P03_RS12425	COG0659	secondary active sulfate transmembrane transporter activity
C5P03_RS12465	COG0697	spore germination
C5P03_RS12470	COG4657	Part of a membrane complex involved in electron transport
C5P03_RS12475	COG2878	Part of a membrane complex involved in electron transport
C5P03_RS12485	COG4658	electron transport chain
C5P03_RS12490	COG4659	FMN binding
C5P03_RS12495	COG4660	Part of a membrane complex involved in electron transport
C5P03_RS12500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
C5P03_RS12505	COG0346	lactoylglutathione lyase activity
C5P03_RS12520	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5P03_RS12525	COG2056	Na+-H+ antiporter family
C5P03_RS12530	COG3300	MHYT domain
C5P03_RS12530	COG5001	Diguanylate cyclase
C5P03_RS12540	COG0513	Belongs to the DEAD box helicase family
C5P03_RS12545	COG2050	protein possibly involved in aromatic compounds catabolism
C5P03_RS12555	COG0277	FAD linked oxidase domain protein
C5P03_RS12555	COG0247	lactate metabolic process
C5P03_RS12565	COG1253	flavin adenine dinucleotide binding
C5P03_RS12570	COG1902	pentaerythritol trinitrate reductase activity
C5P03_RS12580	COG0647	UMP catabolic process
C5P03_RS12585	COG4651	solute:proton antiporter activity
C5P03_RS12585	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5P03_RS12595	COG0367	asparagine synthase
C5P03_RS12615	COG0625	glutathione transferase activity
C5P03_RS12620	COG0625	glutathione transferase activity
C5P03_RS12645	COG0564	pseudouridine synthase activity
C5P03_RS12655	COG0840	transmembrane signaling receptor activity
C5P03_RS12665	COG0670	Belongs to the BI1 family
C5P03_RS12670	COG1289	transmembrane transporter activity
C5P03_RS12675	COG2920	part of a sulfur-relay system
C5P03_RS12680	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
C5P03_RS12685	COG0285	dihydrofolate synthase activity
C5P03_RS12690	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
C5P03_RS12695	COG0101	tRNA pseudouridine synthase activity
C5P03_RS12705	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
C5P03_RS12710	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
C5P03_RS12715	COG0671	phosphoesterase, PA-phosphatase related
C5P03_RS12720	COG1464	Belongs to the NlpA lipoprotein family
C5P03_RS12760	COG0574	Belongs to the PEP-utilizing enzyme family
C5P03_RS12760	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5P03_RS12765	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
C5P03_RS12805	COG0672	)-iron permease
C5P03_RS12850	COG0577	efflux transmembrane transporter activity
C5P03_RS12865	COG1285	pathogenesis
C5P03_RS12910	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5P03_RS12915	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
C5P03_RS12915	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
C5P03_RS12920	COG0527	aspartate kinase activity
C5P03_RS12930	COG1368	sulfuric ester hydrolase activity
C5P03_RS12935	COG1619	proteins homologs of microcin C7 resistance protein MccF
C5P03_RS12945	COG0393	Putative heavy-metal-binding
C5P03_RS12950	COG1252	NADH dehydrogenase
C5P03_RS12955	COG3150	esterase
C5P03_RS12970	COG2354	Protein conserved in bacteria
C5P03_RS12980	COG0047	phosphoribosylformylglycinamidine synthase activity
C5P03_RS12980	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
C5P03_RS12985	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C5P03_RS12990	COG1645	bacterial-type flagellum-dependent swarming motility
C5P03_RS12995	COG1160	GTP binding
C5P03_RS13000	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5P03_RS13005	COG2976	Protein conserved in bacteria
C5P03_RS13010	COG0124	histidyl-tRNA synthetase
C5P03_RS13015	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
C5P03_RS13020	COG1426	Protein conserved in bacteria
C5P03_RS13030	COG0820	rRNA (adenine-C2-)-methyltransferase activity
C5P03_RS13035	COG0105	UTP biosynthetic process
C5P03_RS13040	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5P03_RS13050	COG0633	Ferredoxin
C5P03_RS13055	COG0443	Heat shock 70 kDa protein
C5P03_RS13060	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C5P03_RS13070	COG0822	iron-sulfur transferase activity
C5P03_RS13075	COG1104	cysteine desulfurase activity
C5P03_RS13095	COG3154	lipid carrier protein
C5P03_RS13100	COG0826	peptidase U32
C5P03_RS13105	COG0826	peptidase U32
C5P03_RS13115	COG2897	thiosulfate sulfurtransferase activity
C5P03_RS13120	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_RS13125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
C5P03_RS13130	COG1862	Preprotein translocase
C5P03_RS13135	COG0343	queuine tRNA-ribosyltransferase activity
C5P03_RS13140	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
C5P03_RS13145	COG0517	IMP dehydrogenase activity
C5P03_RS13155	COG3634	alkyl hydroperoxide reductase activity
C5P03_RS13170	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5P03_RS13170	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
C5P03_RS13175	COG0509	glycine decarboxylation via glycine cleavage system
C5P03_RS13180	COG0404	The glycine cleavage system catalyzes the degradation of glycine
C5P03_RS13185	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5P03_RS13190	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
C5P03_RS13215	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C5P03_RS13220	COG0583	DNA-binding transcription factor activity
C5P03_RS13225	COG2814	Major facilitator Superfamily
C5P03_RS13230	COG0444	Belongs to the ABC transporter superfamily
C5P03_RS13235	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_RS13240	COG0601	transmembrane transport
C5P03_RS13250	COG0625	glutathione transferase activity
C5P03_RS13260	COG0483	inositol monophosphate 1-phosphatase activity
C5P03_RS13280	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
C5P03_RS13290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5P03_RS13320	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5P03_RS13325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
C5P03_RS13340	COG0301	tRNA thio-modification
C5P03_RS13340	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5P03_RS13595	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5P03_RS13630	COG2974	May be involved in recombination
C5P03_RS13680	COG0582	viral genome integration into host DNA
C5P03_RS13690	COG4953	penicillin-binding protein 1C
C5P03_RS13695	COG2373	Large extracellular alpha-helical protein
C5P03_RS13710	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
C5P03_RS13745	COG2431	L-lysine efflux transmembrane transporter activity
C5P03_RS13750	COG3124	Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP
C5P03_RS13760	COG1393	Belongs to the ArsC family
C5P03_RS13770	COG4783	chaperone-mediated protein folding
C5P03_RS13775	COG0425	Belongs to the sulfur carrier protein TusA family
C5P03_RS13780	COG0628	permease
C5P03_RS13795	COG3842	ATPase activity
C5P03_RS13800	COG3833	ABC-type maltose transport systems, permease component
C5P03_RS13805	COG1175	transmembrane transport
C5P03_RS13810	COG2182	Extracellular solute-binding protein
C5P03_RS13815	COG3081	Nucleoid-associated protein
C5P03_RS13820	COG3082	Protein of unknown function (DUF1414)
C5P03_RS13825	COG3083	sulfuric ester hydrolase activity
C5P03_RS13830	COG4771	TonB-dependent receptor
C5P03_RS13835	COG1770	oligopeptidase
C5P03_RS13855	COG4574	serine-type endopeptidase inhibitor activity
C5P03_RS13860	COG3085	chromosome segregation
C5P03_RS13870	COG0287	Prephenate dehydrogenase
C5P03_RS13870	COG1605	Chorismate mutase
C5P03_RS13875	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_RS13880	COG0584	glycerophosphoryl diester phosphodiesterase
C5P03_RS13885	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
C5P03_RS13895	COG1349	DNA-binding transcription factor activity
C5P03_RS13900	COG2271	Major facilitator Superfamily
C5P03_RS13905	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
C5P03_RS13910	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
C5P03_RS13915	COG0583	DNA-binding transcription factor activity
C5P03_RS13940	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
C5P03_RS13945	COG0656	L-ascorbic acid biosynthetic process
C5P03_RS13950	COG2814	Major facilitator Superfamily
C5P03_RS13960	COG1294	oxidase, subunit
C5P03_RS13970	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
C5P03_RS13975	COG2979	Protein of unknown function (DUF533)
C5P03_RS13995	COG0583	DNA-binding transcription factor activity
C5P03_RS14005	COG2807	transmembrane transport
C5P03_RS14010	COG1187	pseudouridine synthase activity
C5P03_RS14015	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
C5P03_RS14025	COG0346	lactoylglutathione lyase activity
C5P03_RS14055	COG1166	arginine decarboxylase activity
C5P03_RS14065	COG2195	Cleaves the N-terminal amino acid of tripeptides
C5P03_RS14090	COG2353	YceI-like domain
C5P03_RS14095	COG0583	DNA-binding transcription factor activity
C5P03_RS14105	COG2759	Belongs to the formate--tetrahydrofolate ligase family
C5P03_RS14110	COG0840	transmembrane signaling receptor activity
C5P03_RS14115	COG0302	gtp cyclohydrolase
C5P03_RS14125	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5P03_RS14155	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
C5P03_RS14170	COG0314	molybdopterin synthase activity
C5P03_RS14175	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
C5P03_RS14180	COG0315	cyclic pyranopterin monophosphate synthase activity
C5P03_RS14185	COG0521	Mo-molybdopterin cofactor biosynthetic process
C5P03_RS14190	COG3005	denitrification pathway
C5P03_RS14200	COG0348	domain, Protein
C5P03_RS14205	COG0437	4 iron, 4 sulfur cluster binding
C5P03_RS14210	COG0243	molybdopterin cofactor binding
C5P03_RS14220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_RS14225	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
C5P03_RS14230	COG3850	Histidine kinase
C5P03_RS14235	COG2197	response regulator
C5P03_RS14265	COG0121	glutamine amidotransferase
C5P03_RS14270	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
C5P03_RS14275	COG1960	acyl-CoA dehydrogenase activity
C5P03_RS14280	COG0784	Response regulator, receiver
C5P03_RS14280	COG3437	response regulator, receiver
C5P03_RS14290	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
C5P03_RS14295	COG0328	RNA-DNA hybrid ribonuclease activity
C5P03_RS14300	COG2226	methyltransferase
C5P03_RS14305	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
C5P03_RS14310	COG1388	LysM domain
C5P03_RS14310	COG0741	lytic transglycosylase activity
C5P03_RS14315	COG3021	interspecies interaction between organisms
C5P03_RS14325	COG1607	acyl-coa hydrolase
C5P03_RS14350	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
C5P03_RS14365	COG2911	Protein conserved in bacteria
C5P03_RS14370	COG0729	surface antigen
C5P03_RS14385	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
C5P03_RS14390	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
C5P03_RS14400	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
C5P03_RS14405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
C5P03_RS14410	COG4134	Bacterial extracellular solute-binding protein
C5P03_RS14415	COG4135	transport system, permease component
C5P03_RS14420	COG4136	ATPase activity
C5P03_RS14425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
C5P03_RS14430	COG2951	lytic endotransglycosylase activity
C5P03_RS14435	COG1846	Transcriptional regulator
C5P03_RS14445	COG0033	Phosphoglucomutase
C5P03_RS14450	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
C5P03_RS14455	COG0596	Alpha beta hydrolase
C5P03_RS14470	COG0716	FMN binding
C5P03_RS14480	COG0735	belongs to the Fur family
C5P03_RS14485	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
C5P03_RS14500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_RS14500	COG2190	(PTS) system
C5P03_RS14500	COG1263	PTS System
C5P03_RS14505	COG0363	glucosamine-6-phosphate deaminase activity
C5P03_RS14510	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
C5P03_RS14515	COG1940	carbohydrate kinase activity
C5P03_RS14515	COG1846	Transcriptional regulator
C5P03_RS14545	COG0438	transferase activity, transferring glycosyl groups
C5P03_RS14560	COG3321	synthase
C5P03_RS14560	COG0604	alcohol dehydrogenase
C5P03_RS14585	COG1484	DNA-dependent DNA replication
C5P03_RS14590	COG4584	PFAM Integrase catalytic
C5P03_RS14600	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_RS14620	COG0217	transcriptional regulatory protein
C5P03_RS14625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
C5P03_RS14635	COG4106	trans-aconitate 2-methyltransferase activity
C5P03_RS14640	COG0500	methyltransferase
C5P03_RS14660	COG0450	alkyl hydroperoxide reductase
C5P03_RS14670	COG0583	DNA-binding transcription factor activity
C5P03_RS14680	COG0791	NLP P60 protein
C5P03_RS14695	COG1309	transcriptional regulator
C5P03_RS14735	COG0534	Mate efflux family protein
C5P03_RS14745	COG2841	Protein conserved in bacteria
C5P03_RS14760	COG3217	Mosc domain protein beta barrel domain protein
C5P03_RS14760	COG0633	Ferredoxin
C5P03_RS14760	COG3217	Mosc domain protein beta barrel domain protein
C5P03_RS14760	COG0633	Ferredoxin
C5P03_RS14770	COG0501	Belongs to the peptidase M48B family
C5P03_RS14775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
C5P03_RS14780	COG1073	alpha beta
C5P03_RS14780	COG2226	methyltransferase
C5P03_RS14785	COG0156	8-amino-7-oxononanoate synthase activity
C5P03_RS14790	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
C5P03_RS14810	COG0017	Asparaginyl-tRNA synthetase
C5P03_RS14815	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C5P03_RS14830	COG0583	DNA-binding transcription factor activity
C5P03_RS14835	COG1393	Belongs to the ArsC family
C5P03_RS14840	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
C5P03_RS14845	COG1876	peptidase activity
C5P03_RS14855	COG3263	regulation of cellular component size
C5P03_RS14875	COG1280	lysine exporter protein (LysE YggA)
C5P03_RS14880	COG0840	transmembrane signaling receptor activity
C5P03_RS14900	COG1957	nucleoside hydrolase
C5P03_RS14915	COG1454	alcohol dehydrogenase
C5P03_RS14955	COG2894	cell division
C5P03_RS14965	COG4964	Belongs to the GSP D family
C5P03_RS14995	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
C5P03_RS15000	COG0702	epimerase
C5P03_RS15005	COG2914	Belongs to the UPF0125 (RnfH) family
C5P03_RS15010	COG2867	negative regulation of translational initiation
C5P03_RS15015	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
C5P03_RS15100	COG0583	DNA-binding transcription factor activity
C5P03_RS15105	COG2610	gluconate transmembrane transporter activity
C5P03_RS15110	COG3048	D-serine ammonia-lyase activity
C5P03_RS15120	COG0538	isocitrate dehydrogenase activity
C5P03_RS15125	COG2207	Transcriptional regulator
C5P03_RS15155	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C5P03_RS15160	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_RS15160	COG1263	PTS System
C5P03_RS15165	COG1609	Transcriptional regulator
C5P03_RS15185	COG2814	Major facilitator Superfamily
C5P03_RS15190	COG0109	protoheme IX farnesyltransferase activity
C5P03_RS15200	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
C5P03_RS15205	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
C5P03_RS15260	COG0708	Exodeoxyribonuclease III
C5P03_RS15285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_RS15290	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
C5P03_RS15300	COG0095	Lipoate-protein ligase
C5P03_RS15350	COG1285	pathogenesis
C5P03_RS15380	COG0484	heat shock protein binding
C5P03_RS15385	COG0443	Heat shock 70 kDa protein
C5P03_RS15390	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
C5P03_RS15395	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
C5P03_RS15400	COG0497	DNA recombination
C5P03_RS15405	COG1227	inorganic diphosphatase activity
C5P03_RS15415	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_RS15420	COG0577	efflux transmembrane transporter activity
C5P03_RS15420	COG1136	(ABC) transporter
C5P03_RS15425	COG1538	Outer membrane efflux protein
C5P03_RS15430	COG2375	cellular response to nickel ion
C5P03_RS15435	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
C5P03_RS15445	COG3328	transposase activity
C5P03_RS15450	COG2916	Histone family protein nucleoid-structuring protein H-NS
C5P03_RS15475	COG2169	Transcriptional regulator
C5P03_RS15475	COG1917	Cupin 2, conserved barrel domain protein
C5P03_RS15485	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_RS15490	COG1917	Cupin 2, conserved barrel domain protein
C5P03_RS15490	COG1396	sequence-specific DNA binding
C5P03_RS15505	COG0531	amino acid
C5P03_RS15510	COG0531	amino acid
C5P03_RS15515	COG1283	sodium-dependent phosphate transmembrane transporter activity
C5P03_RS15525	COG3384	dioxygenase
C5P03_RS15540	COG0813	purine-nucleoside phosphorylase activity
C5P03_RS15555	COG1943	Transposase
C5P03_RS15580	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
C5P03_RS15585	COG0083	homoserine kinase activity
C5P03_RS15600	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
C5P03_RS15605	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
C5P03_RS15620	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
C5P03_RS15630	COG0745	RESPONSE REGULATOR receiver
C5P03_RS15645	COG4988	ABC transporter
C5P03_RS15650	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
C5P03_RS15670	COG1720	tRNA m6t6A37 methyltransferase activity
C5P03_RS15690	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
C5P03_RS15695	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS15705	COG2190	(PTS) system
C5P03_RS15720	COG3038	cytochrome b561
C5P03_RS15730	COG0419	ATPase involved in DNA repair
C5P03_RS15735	COG0420	3'-5' exonuclease activity
C5P03_RS15745	COG2974	May be involved in recombination
C5P03_RS15750	COG0405	Gamma-glutamyltransferase
C5P03_RS15755	COG4651	solute:proton antiporter activity
C5P03_RS15755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5P03_RS15760	COG4651	solute:proton antiporter activity
C5P03_RS15760	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
C5P03_RS15775	COG0469	pyruvate kinase activity
C5P03_RS15780	COG3264	Mechanosensitive ion channel
C5P03_RS15780	COG1196	nuclear chromosome segregation
C5P03_RS15815	COG2801	Transposase and inactivated derivatives
C5P03_RS15820	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
C5P03_RS15830	COG3852	Histidine kinase
C5P03_RS15845	COG4662	Binding-protein-dependent transport system inner membrane component
C5P03_RS15855	COG0746	molybdenum cofactor guanylyltransferase activity
C5P03_RS15860	COG0303	'Molybdopterin
C5P03_RS15865	COG1289	transmembrane transporter activity
C5P03_RS15870	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C5P03_RS15905	COG2205	protein histidine kinase activity
C5P03_RS15905	COG0784	Response regulator, receiver
C5P03_RS15915	COG0601	transmembrane transport
C5P03_RS15920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
C5P03_RS15925	COG0444	Belongs to the ABC transporter superfamily
C5P03_RS15930	COG4608	Belongs to the ABC transporter superfamily
C5P03_RS15940	COG2971	BadF BadG BcrA BcrD
C5P03_RS15950	COG0840	transmembrane signaling receptor activity
C5P03_RS15965	COG3724	N-succinylarginine dihydrolase activity
C5P03_RS15970	COG0616	signal peptide processing
C5P03_RS15975	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS15980	COG0583	DNA-binding transcription factor activity
C5P03_RS15990	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
C5P03_RS16000	COG0583	DNA-binding transcription factor activity
C5P03_RS16005	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
C5P03_RS16010	COG1881	PFAM PEBP family protein
C5P03_RS16070	COG0037	tRNA processing
C5P03_RS16075	COG3590	peptidase
C5P03_RS16085	COG0488	(ABC) transporter
C5P03_RS16095	COG0531	amino acid
C5P03_RS16100	COG0814	amino acid
C5P03_RS16115	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
C5P03_RS16120	COG1982	Orn Lys Arg decarboxylase major
C5P03_RS16125	COG0531	amino acid
C5P03_RS16130	COG3710	Transcriptional regulator
C5P03_RS16135	COG0825	malonyl-CoA metabolic process
C5P03_RS16145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
C5P03_RS16150	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_RS16155	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_RS16160	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
C5P03_RS16165	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
C5P03_RS16180	COG0750	zinc metalloprotease
C5P03_RS16185	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
C5P03_RS16190	COG0575	Belongs to the CDS family
C5P03_RS16195	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
C5P03_RS16200	COG0233	cytoplasmic translational termination
C5P03_RS16205	COG0528	UMP kinase activity
C5P03_RS16210	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
C5P03_RS16215	COG0052	Belongs to the universal ribosomal protein uS2 family
C5P03_RS16220	COG0024	Methionine aminopeptidase
C5P03_RS16225	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
C5P03_RS16230	COG2171	N-acyltransferase activity
C5P03_RS16240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
C5P03_RS16240	COG1263	PTS System
C5P03_RS16260	COG4580	involved in the transport of maltose and maltodextrins
C5P03_RS16270	COG0564	pseudouridine synthase activity
C5P03_RS16275	COG3098	single-species biofilm formation
C5P03_RS16300	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
C5P03_RS16310	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C5P03_RS16310	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
C5P03_RS16325	COG1611	Belongs to the LOG family
C5P03_RS16330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
C5P03_RS16335	COG0473	3-isopropylmalate dehydrogenase activity
C5P03_RS16345	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
C5P03_RS16350	COG2363	Small membrane protein
C5P03_RS16360	COG0583	DNA-binding transcription factor activity
C5P03_RS16365	COG0840	transmembrane signaling receptor activity
C5P03_RS16370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
C5P03_RS16385	COG1477	protein flavinylation
C5P03_RS16390	COG2871	sodium ion transport
C5P03_RS16395	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_RS16400	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_RS16405	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_RS16410	COG1805	sodium ion transport
C5P03_RS16415	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
C5P03_RS16420	COG0271	Belongs to the BolA IbaG family
C5P03_RS16425	COG2813	Specifically methylates the guanine in position
C5P03_RS16435	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
C5P03_RS16445	COG2211	Major facilitator Superfamily
C5P03_RS16450	COG3248	Nucleoside-binding outer membrane protein
C5P03_RS16455	COG1666	GTP binding
C5P03_RS16460	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
C5P03_RS16485	COG3459	Glycosyltransferase 36 associated
C5P03_RS16500	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
C5P03_RS16500	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
C5P03_RS16505	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
C5P03_RS16515	COG1151	hydroxylamine reductase activity
C5P03_RS16520	COG0783	Belongs to the Dps family
C5P03_RS16545	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
C5P03_RS16560	COG0300	oxidoreductase activity
C5P03_RS16570	COG0415	Belongs to the DNA photolyase family
C5P03_RS16575	COG0789	Transcriptional regulator
C5P03_RS16580	COG3272	Protein of unknown function (DUF1722)
C5P03_RS16610	COG0077	Prephenate dehydratase
C5P03_RS16610	COG1605	Chorismate mutase
C5P03_RS16635	COG2133	pyrroloquinoline quinone binding
C5P03_RS16655	COG0300	oxidoreductase activity
C5P03_RS16680	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
C5P03_RS16695	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
C5P03_RS16705	COG3813	Protein conserved in bacteria
C5P03_RS16720	COG1280	lysine exporter protein (LysE YggA)
C5P03_RS16730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
C5P03_RS16740	COG0745	RESPONSE REGULATOR receiver
C5P03_RS16750	COG2198	Histidine kinase
C5P03_RS16750	COG0643	Histidine kinase
C5P03_RS16760	COG0835	chemotaxis
C5P03_RS16765	COG0840	transmembrane signaling receptor activity
C5P03_RS16775	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
C5P03_RS16780	COG2201	protein-glutamate methylesterase activity
C5P03_RS16785	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
C5P03_RS16835	COG2199	diguanylate cyclase activity
C5P03_RS16835	COG2200	EAL domain
C5P03_RS16835	COG2203	Gaf domain
C5P03_RS16840	COG0826	peptidase U32
C5P03_RS16845	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
C5P03_RS16850	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
C5P03_RS16880	COG0737	Belongs to the 5'-nucleotidase family
C5P03_RS16900	COG2204	response regulator
C5P03_RS16905	COG0545	Peptidyl-prolyl cis-trans isomerase
C5P03_RS16920	COG1047	Peptidyl-prolyl cis-trans
C5P03_RS16925	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
C5P03_RS16935	COG0784	Response regulator, receiver
C5P03_RS16935	COG0835	chemotaxis
C5P03_RS16940	COG0429	hydrolase of the alpha beta-hydrolase fold
C5P03_RS16945	COG5001	Diguanylate cyclase
C5P03_RS16945	COG4251	negative regulation of phosphorylation
C5P03_RS16945	COG3706	GGDEF domain
C5P03_RS16945	COG2203	Gaf domain
C5P03_RS16950	COG3089	Belongs to the UPF0270 family
C5P03_RS16960	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
C5P03_RS16965	COG0463	Glycosyl transferase, family 2
C5P03_RS16975	COG0726	polysaccharide deacetylase
C5P03_RS16980	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
C5P03_RS16985	COG2076	Multidrug Resistance protein
C5P03_RS16990	COG2076	Multidrug Resistance protein
C5P03_RS16995	COG3954	Phosphoribulokinase
C5P03_RS17010	COG1765	OsmC-like protein
C5P03_RS17025	COG3397	chitin binding
C5P03_RS17050	COG3655	Transcriptional regulator
C5P03_RS17060	COG2814	Major facilitator Superfamily
C5P03_RS17065	COG4771	TonB-dependent receptor
C5P03_RS17085	COG0748	coenzyme F420 binding
C5P03_RS17090	COG3721	Heme iron utilization protein
C5P03_RS17100	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_RS17125	COG0488	(ABC) transporter
C5P03_RS17140	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
C5P03_RS17145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
C5P03_RS17150	COG3178	'Phosphotransferase
C5P03_RS17155	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
C5P03_RS17165	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
C5P03_RS17170	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
C5P03_RS17175	COG2967	ApaG domain
C5P03_RS17180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
C5P03_RS17195	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
C5P03_RS17205	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
C5P03_RS17220	COG3314	Sporulation integral membrane protein YlbJ
C5P03_RS17225	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
C5P03_RS17230	COG0211	Belongs to the bacterial ribosomal protein bL27 family
C5P03_RS17235	COG0261	This protein binds to 23S rRNA in the presence of protein L20
C5P03_RS17240	COG0142	geranyltranstransferase activity
C5P03_RS17245	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
C5P03_RS17250	COG0330	HflC and HflK could
C5P03_RS17255	COG0330	HflC and HflK could
C5P03_RS17260	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
C5P03_RS17265	COG1923	regulation of RNA biosynthetic process
C5P03_RS17270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
C5P03_RS17275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
C5P03_RS17285	COG0802	atpase or kinase
C5P03_RS17315	COG2011	ABC-type metal ion transport system permease component
C5P03_RS17320	COG1464	Belongs to the NlpA lipoprotein family
C5P03_RS17330	COG0840	transmembrane signaling receptor activity
C5P03_RS17355	COG0784	Response regulator, receiver
C5P03_RS17355	COG2198	Histidine kinase
C5P03_RS17355	COG5002	protein histidine kinase activity
C5P03_RS17390	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
C5P03_RS17395	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
C5P03_RS17405	COG2716	regulation of RNA biosynthetic process
C5P03_RS17410	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
C5P03_RS17415	COG3013	Belongs to the UPF0304 family
C5P03_RS17425	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
C5P03_RS17430	COG0280	phosphate acetyltransferase
C5P03_RS17430	COG0857	belongs to the CobB CobQ family
C5P03_RS17435	COG0440	acetolactate synthase activity
C5P03_RS17440	COG0028	Belongs to the TPP enzyme family
C5P03_RS17455	COG0671	phosphoesterase, PA-phosphatase related
C5P03_RS17465	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
C5P03_RS17470	COG0473	3-isopropylmalate dehydrogenase activity
C5P03_RS17475	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
C5P03_RS17480	COG0066	3-isopropylmalate dehydratase activity
C5P03_RS17495	COG4143	(ABC) transporter
C5P03_RS17500	COG1178	ABC-type Fe3 transport system permease component
C5P03_RS17505	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
C5P03_RS17510	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
C5P03_RS17520	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
C5P03_RS17550	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
C5P03_RS17555	COG0564	pseudouridine synthase activity
C5P03_RS17565	COG3300	MHYT domain
C5P03_RS17565	COG5001	Diguanylate cyclase
C5P03_RS17575	COG0459	protein refolding
C5P03_RS17580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
C5P03_RS17585	COG0534	Mate efflux family protein
C5P03_RS17590	COG3030	protein affecting phage T7 exclusion by the F plasmid
C5P03_RS17595	COG1027	Aspartate ammonia-lyase
C5P03_RS17600	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
C5P03_RS17610	COG0477	Major facilitator Superfamily
C5P03_RS17625	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_RS17630	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
C5P03_RS17655	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
C5P03_RS17660	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5P03_RS17665	COG3036	rescue of stalled ribosome
C5P03_RS17670	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
C5P03_RS17680	COG0138	bifunctional purine biosynthesis protein purh
C5P03_RS17685	COG0151	Belongs to the GarS family
C5P03_RS17730	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
C5P03_RS17735	COG0358	DNA primase activity
C5P03_RS17740	COG1610	YqeY-like protein
C5P03_RS17745	COG0828	Belongs to the bacterial ribosomal protein bS21 family
C5P03_RS17750	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
C5P03_RS17760	COG4942	peptidase
C5P03_RS17760	COG1388	LysM domain
C5P03_RS17765	COG1238	metal cluster binding
C5P03_RS17770	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
C5P03_RS17775	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
C5P03_RS17780	COG0585	pseudouridine synthase activity
C5P03_RS17790	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
C5P03_RS17795	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
C5P03_RS17800	COG0148	phosphopyruvate hydratase activity
C5P03_RS17805	COG0504	CTP synthase activity
C5P03_RS17810	COG3956	TIGRFAM MazG family protein
C5P03_RS17815	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
C5P03_RS17820	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5P03_RS17830	COG4807	Protein conserved in bacteria
C5P03_RS17835	COG3023	N-Acetylmuramoyl-L-alanine amidase
C5P03_RS17840	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
C5P03_RS17845	COG1381	Involved in DNA repair and RecF pathway recombination
C5P03_RS17855	COG0571	ribonuclease III activity
C5P03_RS17865	COG0481	GTPase activity
C5P03_RS17880	COG3073	An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish degrading the anti-sigma factor, liberating sigma-E
C5P03_RS17885	COG1595	DNA-templated transcription, initiation
C5P03_RS17890	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
C5P03_RS17940	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
C5P03_RS17945	COG0191	fructose-bisphosphate aldolase activity
C5P03_RS17950	COG0126	phosphoglycerate kinase activity
C5P03_RS17955	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
C5P03_RS17960	COG1940	carbohydrate kinase activity
C5P03_RS17980	COG3054	Bacterial protein of unknown function (YtfJ_HI0045)
C5P03_RS17995	COG1136	(ABC) transporter
C5P03_RS18015	COG0840	transmembrane signaling receptor activity
C5P03_RS18030	COG0529	Catalyzes the synthesis of activated sulfate
C5P03_RS18035	COG3273	potassium ion transport
C5P03_RS18035	COG0471	metal ion transport
C5P03_RS18040	COG2895	sulfate adenylyltransferase (ATP) activity
C5P03_RS18045	COG0175	sulfate reduction
C5P03_RS18050	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
C5P03_RS18050	COG1648	precorrin-2 dehydrogenase activity
C5P03_RS18055	COG0330	HflC and HflK could
C5P03_RS18060	COG1585	Membrane protein implicated in regulation of membrane protease activity
C5P03_RS18065	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
C5P03_RS18065	COG0517	IMP dehydrogenase activity
C5P03_RS18070	COG0488	(ABC) transporter
C5P03_RS18080	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
C5P03_RS18145	COG0789	Transcriptional regulator
C5P03_RS18155	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
C5P03_RS18160	COG1376	ErfK ybiS ycfS ynhG family protein
C5P03_RS18165	COG0668	transmembrane transport
C5P03_RS18175	COG2731	YhcH YjgK YiaL family protein
C5P03_RS18185	COG1794	racemase activity, acting on amino acids and derivatives
C5P03_RS18225	COG0733	neurotransmitter:sodium symporter activity
C5P03_RS18235	COG0733	neurotransmitter:sodium symporter activity
C5P03_RS18250	COG0561	phosphatase activity
C5P03_RS18280	COG1846	Transcriptional regulator
C5P03_RS18285	COG1764	response to oxidative stress
C5P03_RS18290	COG2130	NADP-dependent
C5P03_RS18295	COG0494	nUDIX hydrolase
C5P03_RS18310	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C5P03_RS18315	COG1349	DNA-binding transcription factor activity
C5P03_RS18325	COG1028	Short-chain dehydrogenase reductase Sdr
C5P03_RS18340	COG3730	PTS system glucitol sorbitol-specific
C5P03_RS18345	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
C5P03_RS18370	COG2982	Protein involved in outer membrane biogenesis
C5P03_RS18375	COG1505	serine-type exopeptidase activity
C5P03_RS18380	COG0577	efflux transmembrane transporter activity
C5P03_RS18380	COG1136	(ABC) transporter
C5P03_RS18385	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
C5P03_RS18390	COG0745	RESPONSE REGULATOR receiver
C5P03_RS18395	COG2205	protein histidine kinase activity
C5P03_RS18400	COG2816	NAD+ diphosphatase activity
C5P03_RS18460	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
C5P03_RS18480	COG0513	Belongs to the DEAD box helicase family
C5P03_RS18505	COG2957	Belongs to the agmatine deiminase family
C5P03_RS18515	COG4221	oxidoreductase activity
C5P03_RS18530	COG1024	Enoyl-CoA hydratase
C5P03_RS18540	COG0110	maltose O-acetyltransferase activity
C5P03_RS18550	COG4166	transmembrane transport
C5P03_RS18565	COG1872	DUF167
C5P03_RS18570	COG0762	integral membrane protein
C5P03_RS18575	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
C5P03_RS18580	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
C5P03_RS18595	COG3022	response to hydroperoxide
C5P03_RS18600	COG0513	Belongs to the DEAD box helicase family
C5P03_RS18605	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
C5P03_RS18625	COG0735	belongs to the Fur family
C5P03_RS18630	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
C5P03_RS18645	COG0776	regulation of translation
C5P03_RS18650	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
C5P03_RS18675	COG0560	Phosphoserine phosphatase
C5P03_RS18685	COG0813	purine-nucleoside phosphorylase activity
C5P03_RS18690	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
C5P03_RS18695	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
C5P03_RS18700	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
C5P03_RS18710	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5P03_RS18715	COG0084	hydrolase, TatD family'
C5P03_RS18720	COG2165	general secretion pathway protein
C5P03_RS18735	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
C5P03_RS18740	COG0004	ammonium transporteR
C5P03_RS18790	COG3561	AntA/AntB antirepressor
C5P03_RS18810	COG0582	viral genome integration into host DNA
C5P03_RS18815	COG4974	Belongs to the 'phage' integrase family
C5P03_RS18820	COG2932	Transcriptional regulator
C5P03_RS18905	COG4695	Portal protein
C5P03_RS19045	COG0795	lipopolysaccharide-transporting ATPase activity
C5P03_RS19050	COG0795	lipopolysaccharide-transporting ATPase activity
C5P03_RS19055	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
C5P03_RS19060	COG2927	DNA polymerase III (CHI subunit)
C5P03_RS19070	COG1253	flavin adenine dinucleotide binding
C5P03_RS19075	COG0586	Pfam SNARE associated Golgi protein
C5P03_RS19080	COG1686	Belongs to the peptidase S11 family
C5P03_RS19105	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
C5P03_RS19110	COG0527	aspartate kinase activity
C5P03_RS19115	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
C5P03_RS19125	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
C5P03_RS19130	COG1546	Belongs to the CinA family
C5P03_RS19135	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
C5P03_RS19170	COG1380	Effector of murein hydrolase LrgA
C5P03_RS19175	COG1346	cytolysis
C5P03_RS19190	COG0527	aspartate kinase activity
C5P03_RS19190	COG0460	homoserine dehydrogenase
C5P03_RS19195	COG0626	cystathionine gamma-synthase activity
C5P03_RS19210	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
C5P03_RS19215	COG0814	amino acid
C5P03_RS19220	COG1218	3'(2'),5'-bisphosphate nucleotidase
C5P03_RS19225	COG0494	nUDIX hydrolase
C5P03_RS19230	COG1011	Hydrolase
C5P03_RS19235	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
C5P03_RS19250	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
C5P03_RS19260	COG3156	type II secretion system protein K
C5P03_RS19265	COG4795	General secretion pathway protein
C5P03_RS19270	COG2165	general secretion pathway protein
C5P03_RS19280	COG2165	general secretion pathway protein
C5P03_RS19285	COG1459	type II secretion system
C5P03_RS19290	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
C5P03_RS19310	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
C5P03_RS19315	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
C5P03_RS19335	COG0456	acetyltransferase
C5P03_RS19340	COG3133	Outer membrane lipoprotein
C5P03_RS19355	COG2771	luxR family
C5P03_RS19370	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
C5P03_RS19385	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS19385	COG2213	PTS system mannitol-specific
C5P03_RS19390	COG0246	Mannitol dehydrogenase
C5P03_RS19395	COG3722	fumarate hydratase activity
C5P03_RS19400	COG3263	regulation of cellular component size
C5P03_RS19405	COG0484	heat shock protein binding
C5P03_RS19425	COG1671	Belongs to the UPF0178 family
C5P03_RS19440	COG1988	membrane-bound metal-dependent
C5P03_RS19445	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
C5P03_RS19450	COG0513	Belongs to the DEAD box helicase family
C5P03_RS19475	COG1575	Belongs to the MenA family. Type 1 subfamily
C5P03_RS19480	COG1169	isochorismate synthase
C5P03_RS19485	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
C5P03_RS19490	COG0596	Alpha beta hydrolase
C5P03_RS19495	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
C5P03_RS19505	COG0318	PFAM AMP-dependent synthetase and ligase
C5P03_RS19520	COG3539	Fimbrial protein
C5P03_RS19525	COG3121	Chaperone
C5P03_RS19530	COG3188	usher protein
C5P03_RS19540	COG3539	Fimbrial protein
C5P03_RS19555	COG3291	Pkd domain containing protein
C5P03_RS19560	COG2949	membrane
C5P03_RS19565	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
C5P03_RS19575	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
C5P03_RS19580	COG5380	lipid catabolic process
C5P03_RS19595	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
C5P03_RS19600	COG4533	DNA binding
C5P03_RS19610	COG2873	o-acetylhomoserine
C5P03_RS19620	COG1979	alcohol dehydrogenase
C5P03_RS19640	COG4221	oxidoreductase activity
C5P03_RS19660	COG1285	pathogenesis
C5P03_RS19680	COG1368	sulfuric ester hydrolase activity
C5P03_RS19685	COG1522	sequence-specific DNA binding
C5P03_RS19695	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
C5P03_RS19700	COG1418	mRNA catabolic process
C5P03_RS19705	COG1058	Belongs to the CinA family
C5P03_RS19705	COG1546	Belongs to the CinA family
C5P03_RS19715	COG1129	ABC transporter
C5P03_RS19715	COG0842	Transport permease protein
C5P03_RS19730	COG0561	phosphatase activity
C5P03_RS19735	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
C5P03_RS19745	COG0668	transmembrane transport
C5P03_RS19755	COG1011	Hydrolase
C5P03_RS19770	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
C5P03_RS19775	COG0019	diaminopimelate decarboxylase activity
C5P03_RS19785	COG1965	Belongs to the frataxin family
C5P03_RS19805	COG3072	Adenylate cyclase
C5P03_RS19810	COG0181	hydroxymethylbilane synthase activity
C5P03_RS19820	COG2959	enzyme of heme biosynthesis
C5P03_RS19835	COG1494	fructose-1,6-bisphosphatase
C5P03_RS19885	COG3932	Exopolysaccharide synthesis, ExoD
C5P03_RS19890	COG0814	amino acid
C5P03_RS19905	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
C5P03_RS19910	COG0110	maltose O-acetyltransferase activity
C5P03_RS19955	COG2022	thiamine diphosphate biosynthetic process
C5P03_RS19965	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
C5P03_RS19970	COG0352	thiamine-phosphate diphosphorylase activity
C5P03_RS19975	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
C5P03_RS19995	COG0745	RESPONSE REGULATOR receiver
C5P03_RS20000	COG0642	Histidine kinase
C5P03_RS20005	COG0189	ligase activity
C5P03_RS20030	COG1639	'signal transduction protein
C5P03_RS20040	COG3700	Belongs to the class B bacterial acid phosphatase family
C5P03_RS20050	COG1366	Belongs to the anti-sigma-factor antagonist family
C5P03_RS20055	COG2172	sigma factor antagonist activity
C5P03_RS20060	COG5002	protein histidine kinase activity
C5P03_RS20060	COG2205	protein histidine kinase activity
C5P03_RS20060	COG0784	Response regulator, receiver
C5P03_RS20065	COG3437	response regulator, receiver
C5P03_RS20090	COG0312	modulator of DNA gyrase
C5P03_RS20095	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
C5P03_RS20105	COG3164	Protein of unknown function
C5P03_RS20110	COG1530	ribonuclease E activity
C5P03_RS20115	COG0424	maF-like protein
C5P03_RS20120	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
C5P03_RS20125	COG1792	Involved in formation and maintenance of cell shape
C5P03_RS20130	COG1077	Cell shape determining protein MreB Mrl
C5P03_RS20190	COG2199	diguanylate cyclase activity
C5P03_RS20190	COG2200	EAL domain
C5P03_RS20195	COG2264	protein methyltransferase activity
C5P03_RS20200	COG0387	Pfam Sodium calcium exchanger
C5P03_RS20205	COG2986	histidine ammonia-lyase
C5P03_RS20210	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
C5P03_RS20215	COG0010	Belongs to the arginase family
C5P03_RS20220	COG1228	amidohydrolase
C5P03_RS20225	COG2188	Transcriptional regulator
C5P03_RS20230	COG0288	reversible hydration of carbon dioxide
C5P03_RS20240	COG2177	Part of the ABC transporter FtsEX involved in
C5P03_RS20245	COG2884	Cell division ATP-binding protein ftsE
C5P03_RS20250	COG0552	protein localization to endoplasmic reticulum
C5P03_RS20255	COG0742	ribosomal rna small subunit methyltransferase
C5P03_RS20285	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5P03_RS20290	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
C5P03_RS20300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5P03_RS20310	COG2095	MarC family integral membrane protein
C5P03_RS20320	COG1301	dicarboxylic acid transport
C5P03_RS20345	COG3714	YhhN family
C5P03_RS20370	COG1770	oligopeptidase
C5P03_RS20385	COG2249	NAD(P)H dehydrogenase (quinone) activity
C5P03_RS20420	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
C5P03_RS20440	COG2197	response regulator
C5P03_RS20445	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
C5P03_RS20450	COG2199	diguanylate cyclase activity
C5P03_RS20455	COG1278	Cold shock
C5P03_RS20465	COG3706	GGDEF domain
C5P03_RS20495	COG0840	transmembrane signaling receptor activity
C5P03_RS20510	COG0347	Belongs to the P(II) protein family
C5P03_RS20515	COG0004	ammonium transporteR
C5P03_RS20530	COG0346	lactoylglutathione lyase activity
C5P03_RS20540	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
C5P03_RS20545	COG1074	ATP-dependent DNA helicase activity
C5P03_RS20550	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
C5P03_RS20555	COG2259	Doxx family
C5P03_RS20560	COG1741	Belongs to the pirin family
C5P03_RS20595	COG1176	ABC-type spermidine putrescine transport system, permease component I
C5P03_RS20605	COG3842	ATPase activity
C5P03_RS20615	COG2199	diguanylate cyclase activity
C5P03_RS20615	COG2203	Gaf domain
C5P03_RS20640	COG0753	catalase activity
C5P03_RS20665	COG0494	nUDIX hydrolase
C5P03_RS20670	COG0628	permease
C5P03_RS20675	COG3284	Transcriptional regulator
C5P03_RS20685	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS20685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
C5P03_RS20685	COG3412	dihydroxyacetone kinase, phosphotransfer subunit
C5P03_RS20690	COG1461	Dihydroxyacetone kinase
C5P03_RS20695	COG2376	Dihydroxyacetone kinase
C5P03_RS20705	COG4584	PFAM Integrase catalytic
C5P03_RS20710	COG1484	DNA-dependent DNA replication
C5P03_RS20760	COG0203	ribosomal protein L17
C5P03_RS20765	COG0202	RNA polymerase activity
C5P03_RS20770	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
C5P03_RS20775	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
C5P03_RS20780	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
C5P03_RS20785	COG0257	Belongs to the bacterial ribosomal protein bL36 family
C5P03_RS20790	COG0201	protein transport
C5P03_RS20795	COG0200	Binds to the 23S rRNA
C5P03_RS20800	COG1841	ribosomal large subunit assembly
C5P03_RS20805	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
C5P03_RS20810	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
C5P03_RS20815	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
C5P03_RS20820	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
C5P03_RS20825	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
C5P03_RS20830	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
C5P03_RS20835	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
C5P03_RS20840	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
C5P03_RS20845	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
C5P03_RS20850	COG0255	Belongs to the universal ribosomal protein uL29 family
C5P03_RS20855	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
C5P03_RS20860	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
C5P03_RS20865	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
C5P03_RS20870	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
C5P03_RS20875	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
C5P03_RS20880	COG0089	rRNA binding
C5P03_RS20885	COG0088	Forms part of the polypeptide exit tunnel
C5P03_RS20890	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
C5P03_RS20895	COG0051	transcription antitermination factor activity, RNA binding
C5P03_RS20915	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
C5P03_RS20920	COG2183	response to ionizing radiation
C5P03_RS20940	COG0596	Alpha beta hydrolase
C5P03_RS20945	COG1040	competence protein
C5P03_RS20950	COG0316	Belongs to the HesB IscA family
C5P03_RS20950	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
C5P03_RS20955	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
C5P03_RS20960	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
C5P03_RS20965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5P03_RS20970	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
C5P03_RS20975	COG4942	peptidase
C5P03_RS20985	COG1609	Transcriptional regulator
C5P03_RS20990	COG0800	Aldolase
C5P03_RS20995	COG0129	dihydroxy-acid dehydratase activity
C5P03_RS21000	COG3265	gluconokinase activity
C5P03_RS21005	COG2610	gluconate transmembrane transporter activity
C5P03_RS21010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
C5P03_RS21015	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
C5P03_RS21025	COG0456	acetyltransferase
C5P03_RS21040	COG1295	ribonuclease BN
C5P03_RS21045	COG1217	gtp-binding protein TYPA
C5P03_RS21050	COG0174	glutamine synthetase
C5P03_RS21060	COG3852	Histidine kinase
C5P03_RS21065	COG2204	response regulator
C5P03_RS21070	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
C5P03_RS21075	COG0635	Involved in the biosynthesis of porphyrin-containing compound
C5P03_RS21085	COG3078	GTPase activator activity
C5P03_RS21095	COG0218	Necessary for normal cell division and for the maintenance of normal septation
C5P03_RS21105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
C5P03_RS21110	COG0408	coproporphyrinogen oxidase activity
C5P03_RS21115	COG0009	L-threonylcarbamoyladenylate synthase
C5P03_RS21125	COG0551	DNA topoisomerase type I activity
C5P03_RS21130	COG2922	Belongs to the Smg family
C5P03_RS21135	COG0758	DNA mediated transformation
C5P03_RS21140	COG1652	LysM domain
C5P03_RS21145	COG0242	peptide deformylase activity
C5P03_RS21150	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
C5P03_RS21155	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
C5P03_RS21155	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
C5P03_RS21160	COG0569	domain protein
C5P03_RS21165	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5P03_RS21190	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
C5P03_RS21195	COG0686	Belongs to the AlaDH PNT family
C5P03_RS21200	COG0519	Catalyzes the synthesis of GMP from XMP
C5P03_RS21200	COG0518	GMP synthase (glutamine-hydrolyzing) activity
C5P03_RS21210	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
C5P03_RS21220	COG1012	belongs to the aldehyde dehydrogenase family
C5P03_RS21230	COG2962	Rard protein
C5P03_RS21240	COG1280	lysine exporter protein (LysE YggA)
C5P03_RS21250	COG2391	methyltransferase activity
C5P03_RS21255	COG1280	lysine exporter protein (LysE YggA)
C5P03_RS21260	COG0583	DNA-binding transcription factor activity
C5P03_RS21280	COG2823	Periplasmic or secreted lipoprotein
C5P03_RS21320	COG0210	DNA helicase
C5P03_RS21330	COG3845	ABC transporter
C5P03_RS21335	COG4603	Belongs to the binding-protein-dependent transport system permease family
C5P03_RS21340	COG1079	Belongs to the binding-protein-dependent transport system permease family
C5P03_RS21345	COG0583	DNA-binding transcription factor activity
C5P03_RS21365	COG1262	PFAM Formylglycine-generating sulfatase enzyme
C5P03_RS21370	COG0385	Bile acid
C5P03_RS21420	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
C5P03_RS21435	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
C5P03_RS21440	COG3074	FtsZ-dependent cytokinesis
C5P03_RS21450	COG1045	serine acetyltransferase
C5P03_RS21460	COG0745	RESPONSE REGULATOR receiver
C5P03_RS21465	COG2205	protein histidine kinase activity
C5P03_RS21470	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
C5P03_RS21490	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
C5P03_RS21495	COG2937	Belongs to the GPAT DAPAT family
C5P03_RS21500	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
C5P03_RS21505	COG3161	chorismate lyase activity
C5P03_RS21510	COG1580	Controls the rotational direction of flagella during chemotaxis
C5P03_RS21535	COG1609	Transcriptional regulator
C5P03_RS21540	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
C5P03_RS21555	COG1519	Transferase
C5P03_RS21560	COG0859	PFAM glycosyl transferase family 9
C5P03_RS21565	COG0463	Glycosyl transferase, family 2
C5P03_RS21570	COG0859	PFAM glycosyl transferase family 9
C5P03_RS21575	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
C5P03_RS21580	COG2990	Protein conserved in bacteria
C5P03_RS21585	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
C5P03_RS21595	COG0267	Belongs to the bacterial ribosomal protein bL33 family
C5P03_RS21600	COG0227	Belongs to the bacterial ribosomal protein bL28 family
C5P03_RS21605	COG2003	Belongs to the UPF0758 family
C5P03_RS21610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
C5P03_RS21615	COG0756	dUTP diphosphatase activity
C5P03_RS21620	COG1309	transcriptional regulator
C5P03_RS21625	COG0668	transmembrane transport
C5P03_RS21640	COG0166	Belongs to the GPI family
C5P03_RS21645	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
C5P03_RS21650	COG0583	DNA-binding transcription factor activity
C5P03_RS21690	COG4635	menaquinone-dependent protoporphyrinogen oxidase activity
C5P03_RS21695	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
C5P03_RS21700	COG1739	Uncharacterized protein family UPF0029
C5P03_RS21705	COG0006	proline dipeptidase activity
C5P03_RS21710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
C5P03_RS21715	COG1024	Enoyl-CoA hydratase
C5P03_RS21715	COG1250	3-hydroxyacyl-CoA dehydrogenase
C5P03_RS21720	COG0183	Belongs to the thiolase family
C5P03_RS21745	COG0425	Belongs to the sulfur carrier protein TusA family
C5P03_RS21750	COG0251	oxidation-reduction process
C5P03_RS21755	COG2885	chlorophyll binding
C5P03_RS21760	COG2818	Glycosylase
C5P03_RS21765	COG0752	glycyl-tRNA synthetase alpha subunit
C5P03_RS21770	COG0751	glycine-tRNA ligase activity
C5P03_RS21780	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
C5P03_RS21790	COG2199	diguanylate cyclase activity
C5P03_RS21790	COG2202	Pas domain
C5P03_RS21790	COG2200	EAL domain
C5P03_RS21805	COG0814	amino acid
C5P03_RS21810	COG0348	domain, Protein
C5P03_RS21820	COG0446	pyridine nucleotide-disulphide oxidoreductase
C5P03_RS21825	COG1773	rubredoxin
C5P03_RS21825	COG0426	domain, Protein
C5P03_RS21830	COG3604	Transcriptional regulator
C5P03_RS21835	COG2188	Transcriptional regulator
C5P03_RS21850	COG1609	Transcriptional regulator
C5P03_RS21890	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
C5P03_RS21915	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
C5P03_RS21930	COG3118	belongs to the thioredoxin family
C5P03_RS21935	COG0513	Belongs to the DEAD box helicase family
C5P03_RS21940	COG0248	Ppx GppA phosphatase
C5P03_RS21950	COG0742	ribosomal rna small subunit methyltransferase
C5P03_RS21955	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
C5P03_RS21975	COG0084	hydrolase, TatD family'
C5P03_RS21980	COG0805	protein transport
C5P03_RS21985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
C5P03_RS21995	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
C5P03_RS22000	COG3165	ubiquinone biosynthetic process from chorismate
C5P03_RS22010	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
C5P03_RS22055	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
C5P03_RS22060	COG0848	biopolymer transport protein
C5P03_RS22065	COG0811	peptide transport
C5P03_RS22070	COG0811	peptide transport
C5P03_RS22080	COG2771	luxR family
C5P03_RS22110	COG1484	DNA-dependent DNA replication
C5P03_RS22115	COG4584	PFAM Integrase catalytic
C5P03_RS22170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
C5P03_RS22175	COG1349	DNA-binding transcription factor activity
C5P03_RS22180	COG0745	RESPONSE REGULATOR receiver
C5P03_RS22185	COG2205	protein histidine kinase activity
C5P03_RS22195	COG4452	Inner membrane protein CreD
C5P03_RS22200	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
C5P03_RS22205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
C5P03_RS22210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
C5P03_RS22215	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
C5P03_RS22220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
C5P03_RS22225	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
C5P03_RS22230	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
C5P03_RS22240	COG0356	it plays a direct role in the translocation of protons across the membrane
C5P03_RS22245	COG3312	ion transport
C5P03_RS22250	COG1475	DNA binding
C5P03_RS22255	COG1192	Involved in chromosome partitioning
C5P03_RS22260	COG0357	Ribosomal RNA small subunit methyltransferase G
C5P03_RS22265	COG0445	tRNA wobble uridine modification
C5P03_RS22270	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
C5P03_RS22275	COG4774	siderophore transport
C5P03_RS22280	COG4615	Cyclic peptide transporter
C5P03_RS22285	COG1120	ATPase activity
C5P03_RS22290	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
C5P03_RS22300	COG4774	siderophore transport
C5P03_RS22305	COG4607	ABC-type enterochelin transport system periplasmic component
C5P03_RS22310	COG4604	ABC transporter, ATP-binding protein
C5P03_RS22315	COG4605	iron ion homeostasis
C5P03_RS22320	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
C5P03_RS22325	COG1132	(ABC) transporter
C5P03_RS22330	COG1132	(ABC) transporter
C5P03_RS22330	COG2375	cellular response to nickel ion
C5P03_RS22340	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_RS22350	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
C5P03_RS22365	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
C5P03_RS22370	COG0706	membrane insertase activity
C5P03_RS22375	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
C5P03_RS22380	COG0594	ribonuclease P activity
C5P03_RS22385	COG0230	Belongs to the bacterial ribosomal protein bL34 family
C5P03_RS22390	COG1126	abc transporter atp-binding protein