locus-tag	class	description
WL1483_RS00005	COG0445	tRNA wobble uridine modification
WL1483_RS00015	COG0716	FMN binding
WL1483_RS00030	COG3550	peptidyl-serine autophosphorylation
WL1483_RS00060	COG0732	type I restriction modification DNA specificity domain
WL1483_RS00095	COG4974	Belongs to the 'phage' integrase family
WL1483_RS00100	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
WL1483_RS00105	COG0706	membrane insertase activity
WL1483_RS00110	COG0594	ribonuclease P activity
WL1483_RS00115	COG1126	abc transporter atp-binding protein
WL1483_RS00130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
WL1483_RS00135	COG0592	DNA-directed DNA polymerase activity
WL1483_RS00140	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
WL1483_RS00155	COG2801	Transposase and inactivated derivatives
WL1483_RS00185	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WL1483_RS00190	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WL1483_RS00195	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
WL1483_RS00200	COG0254	rRNA binding
WL1483_RS00205	COG0702	epimerase
WL1483_RS00210	COG0281	malic enzyme
WL1483_RS00215	COG2205	protein histidine kinase activity
WL1483_RS00220	COG0745	RESPONSE REGULATOR receiver
WL1483_RS00240	COG0183	Belongs to the thiolase family
WL1483_RS00245	COG1024	Enoyl-CoA hydratase
WL1483_RS00245	COG1250	3-hydroxyacyl-CoA dehydrogenase
WL1483_RS00250	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WL1483_RS00255	COG0006	proline dipeptidase activity
WL1483_RS00260	COG1739	Uncharacterized protein family UPF0029
WL1483_RS00265	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WL1483_RS00295	COG1042	CoA-binding domain protein
WL1483_RS00295	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WL1483_RS00295	COG0045	succinate-CoA ligase (ADP-forming) activity
WL1483_RS00300	COG0859	PFAM glycosyl transferase family 9
WL1483_RS00305	COG1519	Transferase
WL1483_RS00320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WL1483_RS00325	COG1609	Transcriptional regulator
WL1483_RS00350	COG3161	chorismate lyase activity
WL1483_RS00355	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
WL1483_RS00365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WL1483_RS00395	COG1609	Transcriptional regulator
WL1483_RS00425	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WL1483_RS00430	COG0348	domain, Protein
WL1483_RS00445	COG0814	amino acid
WL1483_RS00465	COG2801	Transposase and inactivated derivatives
WL1483_RS00470	COG0751	glycine-tRNA ligase activity
WL1483_RS00475	COG0752	glycyl-tRNA synthetase alpha subunit
WL1483_RS00480	COG2818	Glycosylase
WL1483_RS00495	COG2885	chlorophyll binding
WL1483_RS00500	COG2358	TRAP transporter, solute receptor (TAXI family
WL1483_RS00510	COG0814	amino acid
WL1483_RS00520	COG0626	cystathionine gamma-synthase activity
WL1483_RS00525	COG0460	homoserine dehydrogenase
WL1483_RS00525	COG0527	aspartate kinase activity
WL1483_RS00535	COG3852	Histidine kinase
WL1483_RS00550	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
WL1483_RS00560	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
WL1483_RS00565	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WL1483_RS00575	COG0137	argininosuccinate synthase activity
WL1483_RS00580	COG0165	Argininosuccinate lyase
WL1483_RS00600	COG0051	transcription antitermination factor activity, RNA binding
WL1483_RS00605	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
WL1483_RS00610	COG0088	Forms part of the polypeptide exit tunnel
WL1483_RS00615	COG0089	rRNA binding
WL1483_RS00620	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
WL1483_RS00625	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
WL1483_RS00630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
WL1483_RS00635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
WL1483_RS00640	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
WL1483_RS00645	COG0255	Belongs to the universal ribosomal protein uL29 family
WL1483_RS00650	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
WL1483_RS00655	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
WL1483_RS00660	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
WL1483_RS00665	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
WL1483_RS00670	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
WL1483_RS00675	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
WL1483_RS00680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
WL1483_RS00685	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
WL1483_RS00690	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
WL1483_RS00695	COG1841	ribosomal large subunit assembly
WL1483_RS00700	COG0200	Binds to the 23S rRNA
WL1483_RS00705	COG0201	protein transport
WL1483_RS00710	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
WL1483_RS00715	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
WL1483_RS00720	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
WL1483_RS00725	COG0202	RNA polymerase activity
WL1483_RS00730	COG0203	ribosomal protein L17
WL1483_RS00755	COG1301	dicarboxylic acid transport
WL1483_RS00765	COG2095	MarC family integral membrane protein
WL1483_RS00775	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WL1483_RS00790	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WL1483_RS00810	COG0742	ribosomal rna small subunit methyltransferase
WL1483_RS00815	COG0552	protein localization to endoplasmic reticulum
WL1483_RS00820	COG2884	Cell division ATP-binding protein ftsE
WL1483_RS00825	COG2177	Part of the ABC transporter FtsEX involved in
WL1483_RS00835	COG0288	reversible hydration of carbon dioxide
WL1483_RS00845	COG1228	amidohydrolase
WL1483_RS00850	COG0010	Belongs to the arginase family
WL1483_RS00855	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
WL1483_RS00860	COG2986	histidine ammonia-lyase
WL1483_RS00875	COG1494	fructose-1,6-bisphosphatase
WL1483_RS00890	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WL1483_RS00895	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
WL1483_RS00905	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
WL1483_RS00915	COG0514	ATP-dependent DNA helicase (RecQ)
WL1483_RS00920	COG2050	protein possibly involved in aromatic compounds catabolism
WL1483_RS00935	COG2959	enzyme of heme biosynthesis
WL1483_RS00940	COG1587	Uroporphyrinogen-III synthase
WL1483_RS00945	COG0181	hydroxymethylbilane synthase activity
WL1483_RS00950	COG3072	Adenylate cyclase
WL1483_RS00960	COG1965	Belongs to the frataxin family
WL1483_RS00970	COG0019	diaminopimelate decarboxylase activity
WL1483_RS00975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
WL1483_RS00990	COG1011	Hydrolase
WL1483_RS00995	COG0668	transmembrane transport
WL1483_RS01020	COG0174	glutamine synthetase
WL1483_RS01025	COG1217	gtp-binding protein TYPA
WL1483_RS01030	COG1295	ribonuclease BN
WL1483_RS01035	COG1968	undecaprenyl-diphosphatase activity
WL1483_RS01040	COG2017	converts alpha-aldose to the beta-anomer
WL1483_RS01045	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
WL1483_RS01050	COG1085	galactose-1-phosphate uridylyltransferase
WL1483_RS01055	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WL1483_RS01060	COG1609	Transcriptional regulator
WL1483_RS01065	COG3250	beta-galactosidase activity
WL1483_RS01075	COG1129	ABC transporter
WL1483_RS01085	COG1063	alcohol dehydrogenase
WL1483_RS01100	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WL1483_RS01115	COG3306	glycosyltransferase involved in LPS biosynthesis
WL1483_RS01135	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
WL1483_RS01140	COG2166	iron-sulfur cluster assembly
WL1483_RS01145	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
WL1483_RS01165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WL1483_RS01170	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WL1483_RS01215	COG0561	phosphatase activity
WL1483_RS01220	COG2267	carboxylic ester hydrolase activity
WL1483_RS01230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WL1483_RS01235	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WL1483_RS01240	COG1758	RNA polymerase activity
WL1483_RS01250	COG0859	PFAM glycosyl transferase family 9
WL1483_RS01255	COG3642	lipopolysaccharide core region biosynthetic process
WL1483_RS01260	COG3706	GGDEF domain
WL1483_RS01285	COG0589	response to stress
WL1483_RS01290	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WL1483_RS01295	COG1528	Iron-storage protein
WL1483_RS01300	COG2081	HI0933 family
WL1483_RS01305	COG3275	phosphorelay sensor kinase activity
WL1483_RS01315	COG3275	phosphorelay sensor kinase activity
WL1483_RS01320	COG3279	Response regulator of the LytR AlgR family
WL1483_RS01325	COG2223	nitrite transmembrane transporter activity
WL1483_RS01330	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
WL1483_RS01335	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
WL1483_RS01350	COG0583	DNA-binding transcription factor activity
WL1483_RS01355	COG4206	TonB-dependent receptor
WL1483_RS01425	COG2801	Transposase and inactivated derivatives
WL1483_RS01450	COG0513	Belongs to the DEAD box helicase family
WL1483_RS01470	COG0454	-acetyltransferase
WL1483_RS01485	COG2391	methyltransferase activity
WL1483_RS01505	COG3932	Exopolysaccharide synthesis, ExoD
WL1483_RS01510	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WL1483_RS01515	COG0561	phosphatase activity
WL1483_RS01525	COG3133	Outer membrane lipoprotein
WL1483_RS01530	COG0456	acetyltransferase
WL1483_RS01545	COG0006	proline dipeptidase activity
WL1483_RS01545	COG0006	proline dipeptidase activity
WL1483_RS01555	COG3038	cytochrome b561
WL1483_RS01565	COG1639	'signal transduction protein
WL1483_RS01570	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WL1483_RS01645	COG1328	CTP reductase activity
WL1483_RS01650	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WL1483_RS01655	COG1716	ATPase activity
WL1483_RS01655	COG5001	Diguanylate cyclase
WL1483_RS01665	COG1448	Aminotransferase
WL1483_RS01670	COG2194	sulfuric ester hydrolase activity
WL1483_RS01685	COG1215	transferase activity, transferring glycosyl groups
WL1483_RS01690	COG1215	transferase activity, transferring glycosyl groups
WL1483_RS01705	COG3118	belongs to the thioredoxin family
WL1483_RS01705	COG0457	Tetratricopeptide repeat
WL1483_RS01755	COG1840	ABC-type Fe3 transport system, periplasmic component
WL1483_RS01765	COG3842	ATPase activity
WL1483_RS01770	COG2837	iron assimilation
WL1483_RS01775	COG1438	arginine binding
WL1483_RS01780	COG1126	abc transporter atp-binding protein
WL1483_RS01785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL1483_RS01790	COG4215	(ABC) transporter
WL1483_RS01795	COG4160	amino acid transport
WL1483_RS01800	COG0039	L-malate dehydrogenase activity
WL1483_RS01805	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
WL1483_RS01810	COG1017	nitric oxide dioxygenase activity
WL1483_RS01810	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WL1483_RS01820	COG4536	flavin adenine dinucleotide binding
WL1483_RS01825	COG4137	Cytochrome C assembly protein
WL1483_RS01830	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
WL1483_RS01835	COG0228	four-way junction DNA binding
WL1483_RS01840	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
WL1483_RS01845	COG0336	Belongs to the RNA methyltransferase TrmD family
WL1483_RS01850	COG0335	large ribosomal subunit rRNA binding
WL1483_RS01860	COG3066	DNA modification
WL1483_RS01865	COG1051	belongs to the nudix hydrolase family
WL1483_RS01875	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
WL1483_RS01880	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
WL1483_RS01885	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WL1483_RS01895	COG0583	DNA-binding transcription factor activity
WL1483_RS01900	COG0640	Transcriptional regulator
WL1483_RS01905	COG0268	Binds directly to 16S ribosomal RNA
WL1483_RS01910	COG0728	peptidoglycan biosynthetic process
WL1483_RS01915	COG0196	riboflavin kinase activity
WL1483_RS01920	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
WL1483_RS01925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
WL1483_RS01930	COG1047	Peptidyl-prolyl cis-trans
WL1483_RS01935	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
WL1483_RS01975	COG0583	DNA-binding transcription factor activity
WL1483_RS01980	COG1741	Belongs to the pirin family
WL1483_RS01985	COG2259	Doxx family
WL1483_RS01990	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
WL1483_RS01995	COG1074	ATP-dependent DNA helicase activity
WL1483_RS02000	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
WL1483_RS02005	COG0513	Belongs to the DEAD box helicase family
WL1483_RS02025	COG3916	Acyl-homoserine-lactone synthase
WL1483_RS02030	COG2771	luxR family
WL1483_RS02040	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
WL1483_RS02050	COG3706	GGDEF domain
WL1483_RS02055	COG3047	cAMP biosynthetic process
WL1483_RS02080	COG2949	membrane
WL1483_RS02085	COG3291	Pkd domain containing protein
WL1483_RS02110	COG2801	Transposase and inactivated derivatives
WL1483_RS02115	COG3188	usher protein
WL1483_RS02125	COG3539	Fimbrial protein
WL1483_RS02145	COG1441	menaquinone biosynthetic process
WL1483_RS02150	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
WL1483_RS02160	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
WL1483_RS02165	COG1169	isochorismate synthase
WL1483_RS02170	COG1575	Belongs to the MenA family. Type 1 subfamily
WL1483_RS02175	COG0840	transmembrane signaling receptor activity
WL1483_RS02220	COG2801	Transposase and inactivated derivatives
WL1483_RS02235	COG3415	Transposase
WL1483_RS02235	COG2801	Transposase and inactivated derivatives
WL1483_RS02260	COG5433	transposase activity
WL1483_RS02265	COG3023	N-Acetylmuramoyl-L-alanine amidase
WL1483_RS02270	COG2801	Transposase and inactivated derivatives
WL1483_RS02305	COG2926	Belongs to the UPF0265 family
WL1483_RS02340	COG1929	Belongs to the glycerate kinase type-1 family
WL1483_RS02350	COG3835	regulator
WL1483_RS02355	COG3112	Uncharacterised protein family (UPF0231)
WL1483_RS02375	COG2252	PERMEase
WL1483_RS02380	COG2376	Dihydroxyacetone kinase
WL1483_RS02385	COG1461	Dihydroxyacetone kinase
WL1483_RS02400	COG0583	DNA-binding transcription factor activity
WL1483_RS02405	COG2957	Belongs to the agmatine deiminase family
WL1483_RS02410	COG0628	permease
WL1483_RS02440	COG1438	arginine binding
WL1483_RS02445	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
WL1483_RS02450	COG0540	Belongs to the ATCase OTCase family
WL1483_RS02465	COG0688	phosphatidylethanolamine metabolic process
WL1483_RS02470	COG1309	transcriptional regulator
WL1483_RS02480	COG0625	glutathione transferase activity
WL1483_RS02515	COG3040	lipid binding
WL1483_RS02520	COG2207	Transcriptional regulator
WL1483_RS02525	COG1979	alcohol dehydrogenase
WL1483_RS02530	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
WL1483_RS02535	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
WL1483_RS02550	COG1522	sequence-specific DNA binding
WL1483_RS02555	COG2502	aspartate--ammonia ligase
WL1483_RS02565	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
WL1483_RS02570	COG1194	a g-specific adenine glycosylase
WL1483_RS02580	COG3267	Type II secretory pathway component ExeA
WL1483_RS02580	COG3409	Peptidoglycan-binding domain 1 protein
WL1483_RS02585	COG0617	tRNA 3'-terminal CCA addition
WL1483_RS02590	COG0306	phosphate transporter
WL1483_RS02595	COG1392	Phosphate transport regulator
WL1483_RS02605	COG1560	Kdo2-lipid A biosynthetic process
WL1483_RS02610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
WL1483_RS02610	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
WL1483_RS02615	COG2827	Endonuclease containing a URI domain
WL1483_RS02625	COG2962	Rard protein
WL1483_RS02630	COG1573	uracil-dna glycosylase
WL1483_RS02640	COG0583	DNA-binding transcription factor activity
WL1483_RS02645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
WL1483_RS02650	COG1121	(ABC) transporter
WL1483_RS02655	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
WL1483_RS02660	COG0739	heme binding
WL1483_RS02670	COG3068	Protein conserved in bacteria
WL1483_RS02690	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
WL1483_RS02695	COG1546	Belongs to the CinA family
WL1483_RS02700	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
WL1483_RS02705	COG2137	regulation of response to DNA damage stimulus
WL1483_RS02710	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
WL1483_RS02715	COG0527	aspartate kinase activity
WL1483_RS02720	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
WL1483_RS02755	COG1376	ErfK ybiS ycfS ynhG family protein
WL1483_RS02770	COG0312	modulator of DNA gyrase
WL1483_RS02775	COG0312	modulator of DNA gyrase
WL1483_RS02780	COG0716	FMN binding
WL1483_RS02785	COG4974	Belongs to the 'phage' integrase family
WL1483_RS02795	COG1970	mechanosensitive ion channel activity
WL1483_RS02805	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
WL1483_RS02815	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
WL1483_RS02820	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
WL1483_RS02825	COG0583	DNA-binding transcription factor activity
WL1483_RS02830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
WL1483_RS02860	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
WL1483_RS02865	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
WL1483_RS02875	COG0338	D12 class N6 adenine-specific DNA methyltransferase
WL1483_RS02880	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
WL1483_RS02890	COG0180	Tryptophanyl-tRNA synthetase
WL1483_RS02905	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
WL1483_RS02915	COG1012	belongs to the aldehyde dehydrogenase family
WL1483_RS02930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WL1483_RS02935	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
WL1483_RS02940	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WL1483_RS02945	COG0175	sulfate reduction
WL1483_RS02950	COG3447	MASE1 domain protein
WL1483_RS02950	COG5001	Diguanylate cyclase
WL1483_RS02950	COG5002	protein histidine kinase activity
WL1483_RS02955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
WL1483_RS02965	COG0657	acetylesterase activity
WL1483_RS02975	COG0523	cobalamin synthesis protein
WL1483_RS02980	COG0477	Major facilitator Superfamily
WL1483_RS02995	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
WL1483_RS03000	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
WL1483_RS03035	COG3029	Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane
WL1483_RS03040	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
WL1483_RS03045	COG1053	succinate dehydrogenase
WL1483_RS03050	COG3097	Belongs to the UPF0267 family
WL1483_RS03060	COG0813	purine-nucleoside phosphorylase activity
WL1483_RS03070	COG0471	metal ion transport
WL1483_RS03070	COG0490	domain, Protein
WL1483_RS03110	COG0012	GTP binding
WL1483_RS03115	COG0193	aminoacyl-tRNA hydrolase activity
WL1483_RS03120	COG0737	Belongs to the 5'-nucleotidase family
WL1483_RS03125	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
WL1483_RS03130	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
WL1483_RS03135	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
WL1483_RS03140	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
WL1483_RS03145	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
WL1483_RS03150	COG2890	protein-(glutamine-N5) methyltransferase activity
WL1483_RS03160	COG2912	Transglutaminase-like superfamily
WL1483_RS03170	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
WL1483_RS03175	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
WL1483_RS03185	COG0585	pseudouridine synthase activity
WL1483_RS03190	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
WL1483_RS03195	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
WL1483_RS03200	COG1238	metal cluster binding
WL1483_RS03215	COG0776	regulation of translation
WL1483_RS03230	COG1872	DUF167
WL1483_RS03235	COG0762	integral membrane protein
WL1483_RS03240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
WL1483_RS03245	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
WL1483_RS03260	COG3022	response to hydroperoxide
WL1483_RS03265	COG0513	Belongs to the DEAD box helicase family
WL1483_RS03270	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
WL1483_RS03290	COG0735	belongs to the Fur family
WL1483_RS03295	COG1007	ATP synthesis coupled electron transport
WL1483_RS03300	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL1483_RS03310	COG0713	ATP synthesis coupled electron transport
WL1483_RS03315	COG0839	Belongs to the complex I subunit 6 family
WL1483_RS03320	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL1483_RS03325	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
WL1483_RS03330	COG1034	ATP synthesis coupled electron transport
WL1483_RS03345	COG0649	NAD binding
WL1483_RS03345	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL1483_RS03350	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL1483_RS03355	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
WL1483_RS03375	COG0745	RESPONSE REGULATOR receiver
WL1483_RS03380	COG3104	oligopeptide transport
WL1483_RS03385	COG1210	Utp--glucose-1-phosphate uridylyltransferase
WL1483_RS03390	COG1555	photosystem II stabilization
WL1483_RS03395	COG1218	3'(2'),5'-bisphosphate nucleotidase
WL1483_RS03400	COG2350	Protein conserved in bacteria
WL1483_RS03405	COG2917	probably involved in intracellular septation
WL1483_RS03410	COG0076	glutamate decarboxylase activity
WL1483_RS03415	COG2985	domain, Protein
WL1483_RS03415	COG0569	domain protein
WL1483_RS03425	COG1278	Cold shock
WL1483_RS03435	COG0840	transmembrane signaling receptor activity
WL1483_RS03445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WL1483_RS03450	COG3445	Acts as a radical domain for damaged PFL and possibly other radical proteins
WL1483_RS03460	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
WL1483_RS03485	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WL1483_RS03490	COG1115	amino acid carrier protein
WL1483_RS03495	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WL1483_RS03500	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL1483_RS03520	COG0714	Associated with various cellular activities
WL1483_RS03525	COG3706	GGDEF domain
WL1483_RS03530	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
WL1483_RS03535	COG1678	Uncharacterized ACR, COG1678
WL1483_RS03540	COG0189	ligase activity
WL1483_RS03545	COG1385	rRNA (uridine-N3-)-methyltransferase activity
WL1483_RS03555	COG3091	SprT-like family
WL1483_RS03565	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
WL1483_RS03570	COG2801	Transposase and inactivated derivatives
WL1483_RS03610	COG3397	chitin binding
WL1483_RS03620	COG0835	chemotaxis
WL1483_RS03620	COG0784	Response regulator, receiver
WL1483_RS03630	COG4181	ATPase activity
WL1483_RS03635	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
WL1483_RS03640	COG1090	epimerase
WL1483_RS03645	COG0857	belongs to the CobB CobQ family
WL1483_RS03645	COG0280	phosphate acetyltransferase
WL1483_RS03650	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
WL1483_RS03655	COG3092	negative regulation of chromosome organization
WL1483_RS03660	COG3013	Belongs to the UPF0304 family
WL1483_RS03665	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
WL1483_RS03670	COG2716	regulation of RNA biosynthetic process
WL1483_RS03680	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
WL1483_RS03685	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
WL1483_RS03700	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
WL1483_RS03705	COG0142	geranyltranstransferase activity
WL1483_RS03710	COG1722	exodeoxyribonuclease VII activity
WL1483_RS03715	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WL1483_RS03720	COG1360	Flagellar Motor Protein
WL1483_RS03735	COG1534	Rna-binding protein
WL1483_RS03740	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
WL1483_RS03745	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WL1483_RS03750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
WL1483_RS03755	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
WL1483_RS03760	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
WL1483_RS03775	COG0779	Required for maturation of 30S ribosomal subunits
WL1483_RS03780	COG0195	Participates in both transcription termination and antitermination
WL1483_RS03785	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
WL1483_RS03790	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
WL1483_RS03795	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
WL1483_RS03800	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
WL1483_RS03805	COG1185	polyribonucleotide nucleotidyltransferase activity
WL1483_RS03810	COG0366	Alpha amylase catalytic
WL1483_RS03825	COG0463	Glycosyl transferase, family 2
WL1483_RS03840	COG2989	Protein conserved in bacteria
WL1483_RS03845	COG3108	Peptidase M15
WL1483_RS03860	COG0252	asparaginase activity
WL1483_RS03880	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WL1483_RS03880	COG1263	PTS System
WL1483_RS03885	COG0366	Alpha amylase catalytic
WL1483_RS03890	COG0110	maltose O-acetyltransferase activity
WL1483_RS03920	COG2801	Transposase and inactivated derivatives
WL1483_RS03925	COG5433	transposase activity
WL1483_RS03935	COG0187	DNA topoisomerase II activity
WL1483_RS03945	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
WL1483_RS03955	COG0583	DNA-binding transcription factor activity
WL1483_RS03980	COG4232	protein-disulfide reductase activity
WL1483_RS03990	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
WL1483_RS04000	COG3160	Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase
WL1483_RS04010	COG0583	DNA-binding transcription factor activity
WL1483_RS04015	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
WL1483_RS04020	COG3842	ATPase activity
WL1483_RS04025	COG1176	ABC-type spermidine putrescine transport system, permease component I
WL1483_RS04030	COG1177	transmembrane transport
WL1483_RS04035	COG1012	belongs to the aldehyde dehydrogenase family
WL1483_RS04080	COG4221	oxidoreductase activity
WL1483_RS04095	COG3811	Belongs to the UPF0386 family
WL1483_RS04100	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WL1483_RS04110	COG4232	protein-disulfide reductase activity
WL1483_RS04120	COG0204	Acyl-transferase
WL1483_RS04125	COG1842	Phage shock protein A
WL1483_RS04145	COG1538	Outer membrane efflux protein
WL1483_RS04150	COG0494	nUDIX hydrolase
WL1483_RS04155	COG3151	Protein conserved in bacteria
WL1483_RS04165	COG3150	esterase
WL1483_RS04180	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WL1483_RS04205	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
WL1483_RS04210	COG1595	DNA-templated transcription, initiation
WL1483_RS04220	COG3026	antisigma factor binding
WL1483_RS04230	COG0481	GTPase activity
WL1483_RS04245	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
WL1483_RS04250	COG1381	Involved in DNA repair and RecF pathway recombination
WL1483_RS04255	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
WL1483_RS04265	COG3023	N-Acetylmuramoyl-L-alanine amidase
WL1483_RS04270	COG4807	Protein conserved in bacteria
WL1483_RS04280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WL1483_RS04285	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
WL1483_RS04290	COG3956	TIGRFAM MazG family protein
WL1483_RS04295	COG0504	CTP synthase activity
WL1483_RS04300	COG0148	phosphopyruvate hydratase activity
WL1483_RS04310	COG2801	Transposase and inactivated derivatives
WL1483_RS04320	COG2801	Transposase and inactivated derivatives
WL1483_RS04335	COG0543	2 iron, 2 sulfur cluster binding
WL1483_RS04350	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WL1483_RS04360	COG4166	transmembrane transport
WL1483_RS04375	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
WL1483_RS04380	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
WL1483_RS04385	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
WL1483_RS04400	COG1024	Enoyl-CoA hydratase
WL1483_RS04415	COG4221	oxidoreductase activity
WL1483_RS04420	COG2226	methyltransferase
WL1483_RS04430	COG1765	OsmC-like protein
WL1483_RS04445	COG3954	Phosphoribulokinase
WL1483_RS04455	COG0429	hydrolase of the alpha beta-hydrolase fold
WL1483_RS04460	COG0835	chemotaxis
WL1483_RS04460	COG0784	Response regulator, receiver
WL1483_RS04475	COG3529	nucleic-acid-binding protein containing a Zn-ribbon domain
WL1483_RS04480	COG1047	Peptidyl-prolyl cis-trans
WL1483_RS04485	COG2900	Belongs to the SlyX family
WL1483_RS04495	COG0545	Peptidyl-prolyl cis-trans isomerase
WL1483_RS04500	COG1940	carbohydrate kinase activity
WL1483_RS04505	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WL1483_RS04510	COG0126	phosphoglycerate kinase activity
WL1483_RS04520	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WL1483_RS04530	COG5002	protein histidine kinase activity
WL1483_RS04530	COG2198	Histidine kinase
WL1483_RS04530	COG0784	Response regulator, receiver
WL1483_RS04545	COG0784	Response regulator, receiver
WL1483_RS04545	COG2205	protein histidine kinase activity
WL1483_RS04555	COG0840	transmembrane signaling receptor activity
WL1483_RS04565	COG1464	Belongs to the NlpA lipoprotein family
WL1483_RS04570	COG2011	ABC-type metal ion transport system permease component
WL1483_RS04575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
WL1483_RS04590	COG0848	biopolymer transport protein
WL1483_RS04595	COG0811	peptide transport
WL1483_RS04600	COG0811	peptide transport
WL1483_RS04615	COG4174	ABC transporter (Permease)
WL1483_RS04620	COG4239	(ABC) transporter, permease
WL1483_RS04630	COG0444	Belongs to the ABC transporter superfamily
WL1483_RS04635	COG4608	Belongs to the ABC transporter superfamily
WL1483_RS04660	COG0281	malic enzyme
WL1483_RS04665	COG3290	protein histidine kinase activity
WL1483_RS04675	COG0697	spore germination
WL1483_RS04685	COG1012	belongs to the aldehyde dehydrogenase family
WL1483_RS04690	COG3284	Transcriptional regulator
WL1483_RS04695	COG1960	acyl-CoA dehydrogenase activity
WL1483_RS04700	COG1804	L-carnitine dehydratase bile acid-inducible protein F
WL1483_RS04705	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
WL1483_RS04720	COG0471	metal ion transport
WL1483_RS04725	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WL1483_RS04730	COG0174	glutamine synthetase
WL1483_RS04735	COG0840	transmembrane signaling receptor activity
WL1483_RS04745	COG0366	Alpha amylase catalytic
WL1483_RS04750	COG0545	Peptidyl-prolyl cis-trans isomerase
WL1483_RS04755	COG0071	Belongs to the small heat shock protein (HSP20) family
WL1483_RS04770	COG0159	tryptophan synthase activity
WL1483_RS04775	COG0133	tryptophan synthase activity
WL1483_RS04780	COG0135	phosphoribosylanthranilate isomerase activity
WL1483_RS04780	COG0134	indole-3-glycerol-phosphate synthase activity
WL1483_RS04785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WL1483_RS04790	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
WL1483_RS04790	COG0512	Glutamine amidotransferase of anthranilate synthase
WL1483_RS04795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
WL1483_RS04800	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
WL1483_RS04810	COG0009	L-threonylcarbamoyladenylate synthase
WL1483_RS04820	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
WL1483_RS04830	COG2801	Transposase and inactivated derivatives
WL1483_RS04850	COG0531	amino acid
WL1483_RS04870	COG0174	glutamine synthetase
WL1483_RS04890	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WL1483_RS04890	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WL1483_RS04890	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WL1483_RS04895	COG0673	inositol 2-dehydrogenase activity
WL1483_RS04905	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WL1483_RS04910	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WL1483_RS04915	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
WL1483_RS04920	COG0251	oxidation-reduction process
WL1483_RS04940	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WL1483_RS04955	COG2207	Transcriptional regulator
WL1483_RS04965	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WL1483_RS04975	COG3264	Mechanosensitive ion channel
WL1483_RS04975	COG1196	nuclear chromosome segregation
WL1483_RS04980	COG2190	(PTS) system
WL1483_RS04990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WL1483_RS05000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
WL1483_RS05015	COG3437	response regulator, receiver
WL1483_RS05015	COG2770	Histidine kinase
WL1483_RS05020	COG1720	tRNA m6t6A37 methyltransferase activity
WL1483_RS05035	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
WL1483_RS05040	COG4988	ABC transporter
WL1483_RS05075	COG0745	RESPONSE REGULATOR receiver
WL1483_RS05085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
WL1483_RS05095	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
WL1483_RS05110	COG3381	protein complex oligomerization
WL1483_RS05120	COG3005	denitrification pathway
WL1483_RS05125	COG0745	RESPONSE REGULATOR receiver
WL1483_RS05135	COG0784	Response regulator, receiver
WL1483_RS05135	COG2198	Histidine kinase
WL1483_RS05135	COG2205	protein histidine kinase activity
WL1483_RS05145	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
WL1483_RS05150	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
WL1483_RS05155	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WL1483_RS05155	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
WL1483_RS05180	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
WL1483_RS05185	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WL1483_RS05190	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
WL1483_RS05195	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
WL1483_RS05210	COG4172	Belongs to the ABC transporter superfamily
WL1483_RS05215	COG0747	negative chemotaxis
WL1483_RS05220	COG0601	transmembrane transport
WL1483_RS05225	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WL1483_RS05245	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
WL1483_RS05250	COG0739	heme binding
WL1483_RS05255	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WL1483_RS05275	COG0693	protein deglycase activity
WL1483_RS05280	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
WL1483_RS05285	COG1666	GTP binding
WL1483_RS05290	COG3248	Nucleoside-binding outer membrane protein
WL1483_RS05295	COG2211	Major facilitator Superfamily
WL1483_RS05310	COG2813	Specifically methylates the guanine in position
WL1483_RS05320	COG0271	Belongs to the BolA IbaG family
WL1483_RS05325	COG1726	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WL1483_RS05330	COG1805	sodium ion transport
WL1483_RS05335	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WL1483_RS05340	COG1347	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WL1483_RS05345	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
WL1483_RS05350	COG2871	sodium ion transport
WL1483_RS05355	COG1477	protein flavinylation
WL1483_RS05360	COG2991	Protein conserved in bacteria
WL1483_RS05370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WL1483_RS05380	COG0583	DNA-binding transcription factor activity
WL1483_RS05390	COG2363	Small membrane protein
WL1483_RS05395	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
WL1483_RS05405	COG0473	3-isopropylmalate dehydrogenase activity
WL1483_RS05410	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WL1483_RS05415	COG1611	Belongs to the LOG family
WL1483_RS05430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WL1483_RS05430	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
WL1483_RS05440	COG0697	spore germination
WL1483_RS05445	COG5595	Zn-ribbon-containing, possibly nucleic-acid-binding protein (DUF2310)
WL1483_RS05470	COG3098	single-species biofilm formation
WL1483_RS05490	COG3590	peptidase
WL1483_RS05530	COG0791	NLP P60 protein
WL1483_RS05560	COG1605	Chorismate mutase
WL1483_RS05560	COG0077	Prephenate dehydratase
WL1483_RS05585	COG3272	Protein of unknown function (DUF1722)
WL1483_RS05590	COG0789	Transcriptional regulator
WL1483_RS05620	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
WL1483_RS05640	COG0783	Belongs to the Dps family
WL1483_RS05645	COG1151	hydroxylamine reductase activity
WL1483_RS05650	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WL1483_RS05655	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
WL1483_RS05665	COG3083	sulfuric ester hydrolase activity
WL1483_RS05670	COG3082	Protein of unknown function (DUF1414)
WL1483_RS05675	COG3081	Nucleoid-associated protein
WL1483_RS05685	COG1175	transmembrane transport
WL1483_RS05690	COG3833	ABC-type maltose transport systems, permease component
WL1483_RS05695	COG3842	ATPase activity
WL1483_RS05705	COG0596	Alpha beta hydrolase
WL1483_RS05720	COG0425	Belongs to the sulfur carrier protein TusA family
WL1483_RS05725	COG4783	chaperone-mediated protein folding
WL1483_RS05730	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WL1483_RS05735	COG1393	Belongs to the ArsC family
WL1483_RS05750	COG0517	IMP dehydrogenase activity
WL1483_RS05755	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
WL1483_RS05760	COG0343	queuine tRNA-ribosyltransferase activity
WL1483_RS05765	COG1862	Preprotein translocase
WL1483_RS05770	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WL1483_RS05775	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WL1483_RS05790	COG0826	peptidase U32
WL1483_RS05795	COG0826	peptidase U32
WL1483_RS05800	COG3154	lipid carrier protein
WL1483_RS05815	COG1959	2 iron, 2 sulfur cluster binding
WL1483_RS05820	COG1104	cysteine desulfurase activity
WL1483_RS05825	COG0822	iron-sulfur transferase activity
WL1483_RS05835	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WL1483_RS05840	COG0443	Heat shock 70 kDa protein
WL1483_RS05845	COG0633	Ferredoxin
WL1483_RS05855	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WL1483_RS05870	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WL1483_RS05885	COG0017	Asparaginyl-tRNA synthetase
WL1483_RS05900	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WL1483_RS05905	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WL1483_RS05910	COG0156	8-amino-7-oxononanoate synthase activity
WL1483_RS05920	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
WL1483_RS05925	COG0501	Belongs to the peptidase M48B family
WL1483_RS05930	COG0840	transmembrane signaling receptor activity
WL1483_RS05945	COG0493	'glutamate synthase
WL1483_RS05950	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
WL1483_RS05950	COG0674	pyruvate-flavodoxin oxidoreductase activity
WL1483_RS05950	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
WL1483_RS05950	COG1013	pyruvate-flavodoxin oxidoreductase activity
WL1483_RS05955	COG2841	Protein conserved in bacteria
WL1483_RS05960	COG0642	Histidine kinase
WL1483_RS05975	COG0300	oxidoreductase activity
WL1483_RS05985	COG1022	Amp-dependent synthetase and ligase
WL1483_RS06000	COG0534	Mate efflux family protein
WL1483_RS06020	COG1342	Belongs to the UPF0251 family
WL1483_RS06035	COG1309	transcriptional regulator
WL1483_RS06050	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WL1483_RS06060	COG1280	lysine exporter protein (LysE YggA)
WL1483_RS06065	COG0826	peptidase U32
WL1483_RS06070	COG2205	protein histidine kinase activity
WL1483_RS06110	COG2801	Transposase and inactivated derivatives
WL1483_RS06130	COG3706	GGDEF domain
WL1483_RS06145	COG2226	methyltransferase
WL1483_RS06165	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
WL1483_RS06190	COG0300	oxidoreductase activity
WL1483_RS06200	COG0745	RESPONSE REGULATOR receiver
WL1483_RS06205	COG5002	protein histidine kinase activity
WL1483_RS06225	COG1940	carbohydrate kinase activity
WL1483_RS06230	COG3142	Participates in the control of copper homeostasis
WL1483_RS06235	COG0545	Peptidyl-prolyl cis-trans isomerase
WL1483_RS06250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
WL1483_RS06255	COG0678	peroxiredoxin activity
WL1483_RS06265	COG0019	diaminopimelate decarboxylase activity
WL1483_RS06270	COG1115	amino acid carrier protein
WL1483_RS06285	COG0534	Mate efflux family protein
WL1483_RS06295	COG0281	malic enzyme
WL1483_RS06315	COG0500	methyltransferase
WL1483_RS06320	COG4106	trans-aconitate 2-methyltransferase activity
WL1483_RS06325	COG1801	Protein of unknown function DUF72
WL1483_RS06335	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
WL1483_RS06340	COG0217	transcriptional regulatory protein
WL1483_RS06345	COG1966	Carbon starvation protein
WL1483_RS06350	COG3279	Response regulator of the LytR AlgR family
WL1483_RS06355	COG3275	phosphorelay sensor kinase activity
WL1483_RS06365	COG1012	belongs to the aldehyde dehydrogenase family
WL1483_RS06365	COG1454	alcohol dehydrogenase
WL1483_RS06370	COG2095	MarC family integral membrane protein
WL1483_RS06380	COG0601	transmembrane transport
WL1483_RS06385	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WL1483_RS06400	COG0861	Integral membrane protein TerC family
WL1483_RS06405	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
WL1483_RS06420	COG0840	transmembrane signaling receptor activity
WL1483_RS06425	COG0840	transmembrane signaling receptor activity
WL1483_RS06435	COG2971	BadF BadG BcrA BcrD
WL1483_RS06445	COG4608	Belongs to the ABC transporter superfamily
WL1483_RS06455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WL1483_RS06460	COG0601	transmembrane transport
WL1483_RS06495	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WL1483_RS06515	COG0436	Aminotransferase
WL1483_RS06525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WL1483_RS06530	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
WL1483_RS06535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
WL1483_RS06545	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
WL1483_RS06550	COG0505	Belongs to the CarA family
WL1483_RS06555	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
WL1483_RS06570	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
WL1483_RS06605	COG3220	belongs to the UPF0276 family
WL1483_RS06650	COG0716	FMN binding
WL1483_RS06665	COG0596	Alpha beta hydrolase
WL1483_RS06670	COG3057	Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated
WL1483_RS06675	COG0033	Phosphoglucomutase
WL1483_RS06680	COG2194	sulfuric ester hydrolase activity
WL1483_RS06685	COG4574	serine-type endopeptidase inhibitor activity
WL1483_RS06735	COG4977	sequence-specific DNA binding
WL1483_RS06885	COG1196	nuclear chromosome segregation
WL1483_RS06885	COG0739	heme binding
WL1483_RS06885	COG0741	lytic transglycosylase activity
WL1483_RS06895	COG2197	response regulator
WL1483_RS06905	COG0583	DNA-binding transcription factor activity
WL1483_RS06910	COG3085	chromosome segregation
WL1483_RS06915	COG1940	carbohydrate kinase activity
WL1483_RS06915	COG1846	Transcriptional regulator
WL1483_RS06920	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
WL1483_RS06925	COG0363	glucosamine-6-phosphate deaminase activity
WL1483_RS06930	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WL1483_RS06930	COG2190	(PTS) system
WL1483_RS06930	COG1263	PTS System
WL1483_RS06945	COG0735	belongs to the Fur family
WL1483_RS06955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WL1483_RS06960	COG1677	Flagellar hook-basal body complex protein FliE
WL1483_RS06970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WL1483_RS07025	COG1684	flagellar biosynthetic protein fliR
WL1483_RS07035	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
WL1483_RS07060	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
WL1483_RS07065	COG2198	Histidine kinase
WL1483_RS07065	COG0643	Histidine kinase
WL1483_RS07065	COG0784	Response regulator, receiver
WL1483_RS07070	COG2201	protein-glutamate methylesterase activity
WL1483_RS07075	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WL1483_RS07080	COG1360	Flagellar Motor Protein
WL1483_RS07085	COG1192	Involved in chromosome partitioning
WL1483_RS07095	COG0835	chemotaxis
WL1483_RS07105	COG4133	protoheme IX ABC transporter activity
WL1483_RS07110	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WL1483_RS07115	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WL1483_RS07120	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
WL1483_RS07125	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
WL1483_RS07130	COG1138	Cytochrome C-type biogenesis protein
WL1483_RS07135	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WL1483_RS07145	COG4235	cytochrome complex assembly
WL1483_RS07145	COG3088	subunit of a heme lyase
WL1483_RS07160	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
WL1483_RS07180	COG0259	pyridoxamine-phosphate oxidase activity
WL1483_RS07205	COG0625	glutathione transferase activity
WL1483_RS07210	COG3153	acetyltransferase
WL1483_RS07215	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
WL1483_RS07230	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WL1483_RS07240	COG0583	DNA-binding transcription factor activity
WL1483_RS07245	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS07250	COG0616	signal peptide processing
WL1483_RS07255	COG3724	N-succinylarginine dihydrolase activity
WL1483_RS07265	COG1301	dicarboxylic acid transport
WL1483_RS07270	COG2431	L-lysine efflux transmembrane transporter activity
WL1483_RS07280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
WL1483_RS07300	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WL1483_RS07305	COG3300	MHYT domain
WL1483_RS07305	COG5001	Diguanylate cyclase
WL1483_RS07320	COG4953	penicillin-binding protein 1C
WL1483_RS07325	COG0477	Major facilitator Superfamily
WL1483_RS07335	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WL1483_RS07335	COG0301	tRNA thio-modification
WL1483_RS07355	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WL1483_RS07365	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
WL1483_RS07370	COG4104	PAAR repeat-containing protein
WL1483_RS07385	COG3979	chitinase
WL1483_RS07390	COG0493	'glutamate synthase
WL1483_RS07395	COG0069	glutamate synthase activity
WL1483_RS07395	COG0067	glutamate synthase
WL1483_RS07395	COG0070	glutamate synthase
WL1483_RS07400	COG1242	4 iron, 4 sulfur cluster binding
WL1483_RS07415	COG0582	viral genome integration into host DNA
WL1483_RS07425	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
WL1483_RS07430	COG2867	negative regulation of translational initiation
WL1483_RS07435	COG2914	Belongs to the UPF0125 (RnfH) family
WL1483_RS07445	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WL1483_RS07450	COG1454	alcohol dehydrogenase
WL1483_RS07500	COG0497	DNA recombination
WL1483_RS07505	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
WL1483_RS07510	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
WL1483_RS07515	COG0443	Heat shock 70 kDa protein
WL1483_RS07520	COG0484	heat shock protein binding
WL1483_RS07525	COG1285	pathogenesis
WL1483_RS07570	COG1566	PFAM secretion protein HlyD family protein
WL1483_RS07575	COG1136	(ABC) transporter
WL1483_RS07575	COG0577	efflux transmembrane transporter activity
WL1483_RS07585	COG0577	efflux transmembrane transporter activity
WL1483_RS07585	COG1136	(ABC) transporter
WL1483_RS07590	COG5001	Diguanylate cyclase
WL1483_RS07590	COG3300	MHYT domain
WL1483_RS07600	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
WL1483_RS07605	COG3384	dioxygenase
WL1483_RS07630	COG0788	formyltetrahydrofolate deformylase activity
WL1483_RS07650	COG2091	lysine biosynthetic process via aminoadipic acid
WL1483_RS07655	COG0791	NLP P60 protein
WL1483_RS07660	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
WL1483_RS07680	COG0746	molybdenum cofactor guanylyltransferase activity
WL1483_RS07685	COG1136	(ABC) transporter
WL1483_RS07690	COG4662	Binding-protein-dependent transport system inner membrane component
WL1483_RS07705	COG3852	Histidine kinase
WL1483_RS07715	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
WL1483_RS07730	COG5433	transposase activity
WL1483_RS07760	COG3383	formate dehydrogenase (NAD+) activity
WL1483_RS07760	COG3383	formate dehydrogenase (NAD+) activity
WL1483_RS07765	COG0437	4 iron, 4 sulfur cluster binding
WL1483_RS07795	COG3408	Glycogen debranching enzyme
WL1483_RS07795	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
WL1483_RS07805	COG1881	PFAM PEBP family protein
WL1483_RS07820	COG0708	Exodeoxyribonuclease III
WL1483_RS07865	COG1280	lysine exporter protein (LysE YggA)
WL1483_RS07875	COG3525	Glycosyl hydrolase, family 20, catalytic domain
WL1483_RS07880	COG3263	regulation of cellular component size
WL1483_RS07915	COG1752	Esterase of the alpha-beta hydrolase superfamily
WL1483_RS07925	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
WL1483_RS07940	COG0281	malic enzyme
WL1483_RS07960	COG2233	PERMEase
WL1483_RS07965	COG0583	DNA-binding transcription factor activity
WL1483_RS07975	COG0450	alkyl hydroperoxide reductase
WL1483_RS07980	COG1876	peptidase activity
WL1483_RS07985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WL1483_RS07990	COG1393	Belongs to the ArsC family
WL1483_RS08000	COG0105	UTP biosynthetic process
WL1483_RS08005	COG0820	rRNA (adenine-C2-)-methyltransferase activity
WL1483_RS08015	COG1426	Protein conserved in bacteria
WL1483_RS08020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
WL1483_RS08025	COG0124	histidyl-tRNA synthetase
WL1483_RS08030	COG2976	Protein conserved in bacteria
WL1483_RS08035	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WL1483_RS08040	COG1160	GTP binding
WL1483_RS08045	COG1645	bacterial-type flagellum-dependent swarming motility
WL1483_RS08050	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
WL1483_RS08055	COG2027	D-alanyl-D-alanine carboxypeptidase
WL1483_RS08060	COG1061	Type III restriction enzyme res subunit
WL1483_RS08065	COG1566	PFAM secretion protein HlyD family protein
WL1483_RS08090	COG2015	COG2015, Alkyl sulfatase and related hydrolases
WL1483_RS08100	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
WL1483_RS08130	COG0590	tRNA wobble adenosine to inosine editing
WL1483_RS08135	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WL1483_RS08155	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
WL1483_RS08170	COG1278	Cold shock
WL1483_RS08190	COG4166	transmembrane transport
WL1483_RS08195	COG1349	DNA-binding transcription factor activity
WL1483_RS08200	COG1882	Formate acetyltransferase
WL1483_RS08205	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
WL1483_RS08210	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
WL1483_RS08235	COG4166	transmembrane transport
WL1483_RS08240	COG0622	Phosphoesterase
WL1483_RS08255	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
WL1483_RS08260	COG0835	chemotaxis
WL1483_RS08260	COG0784	Response regulator, receiver
WL1483_RS08270	COG1815	bacterial-type flagellum-dependent cell motility
WL1483_RS08290	COG4787	bacterial-type flagellum-dependent cell motility
WL1483_RS08300	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WL1483_RS08305	COG1706	bacterial-type flagellum-dependent cell motility
WL1483_RS08310	COG1705	Flagellar rod assembly protein muramidase FlgJ
WL1483_RS08310	COG3951	Flagellar rod assembly protein muramidase FlgJ
WL1483_RS08325	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WL1483_RS08330	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WL1483_RS08370	COG2089	acid synthase
WL1483_RS08380	COG1083	cytidylyl-transferase
WL1483_RS08395	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS08400	COG0318	PFAM AMP-dependent synthetase and ligase
WL1483_RS08415	COG1216	Glycosyl transferase, family 2
WL1483_RS08435	COG1215	transferase activity, transferring glycosyl groups
WL1483_RS08445	COG5433	transposase activity
WL1483_RS08455	COG2801	Transposase and inactivated derivatives
WL1483_RS08475	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WL1483_RS08480	COG1086	Polysaccharide biosynthesis protein
WL1483_RS08485	COG2239	Acts as a magnesium transporter
WL1483_RS08495	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
WL1483_RS08500	COG2716	regulation of RNA biosynthetic process
WL1483_RS08510	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
WL1483_RS08515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
WL1483_RS08520	COG2271	Major facilitator Superfamily
WL1483_RS08525	COG1349	DNA-binding transcription factor activity
WL1483_RS08530	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WL1483_RS08535	COG0584	glycerophosphoryl diester phosphodiesterase
WL1483_RS08540	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WL1483_RS08545	COG1605	Chorismate mutase
WL1483_RS08545	COG0287	Prephenate dehydrogenase
WL1483_RS08565	COG2850	peptidyl-arginine hydroxylation
WL1483_RS08570	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
WL1483_RS08575	COG2915	High frequency lysogenization protein hflD homolog
WL1483_RS08580	COG0482	sulfurtransferase activity
WL1483_RS08590	COG1187	pseudouridine synthase activity
WL1483_RS08595	COG0538	isocitrate dehydrogenase activity
WL1483_RS08620	COG0798	PFAM Bile acid sodium symporter
WL1483_RS08625	COG1393	Belongs to the ArsC family
WL1483_RS08640	COG1448	Aminotransferase
WL1483_RS08650	COG0564	pseudouridine synthase activity
WL1483_RS08665	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
WL1483_RS08675	COG0625	glutathione transferase activity
WL1483_RS08690	COG3437	response regulator, receiver
WL1483_RS08695	COG0583	DNA-binding transcription factor activity
WL1483_RS08715	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
WL1483_RS08740	COG0583	DNA-binding transcription factor activity
WL1483_RS08745	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
WL1483_RS08750	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
WL1483_RS08755	COG0539	negative regulation of cytoplasmic translation
WL1483_RS08760	COG0776	regulation of translation
WL1483_RS08765	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
WL1483_RS08770	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
WL1483_RS08775	COG0284	orotidine-5'-phosphate decarboxylase activity
WL1483_RS08790	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
WL1483_RS08795	COG0602	queuosine metabolic process
WL1483_RS08800	COG3530	Putative quorum-sensing-regulated virulence factor
WL1483_RS08805	COG2096	Adenosyltransferase
WL1483_RS08810	COG2916	Histone family protein nucleoid-structuring protein H-NS
WL1483_RS08815	COG1757	Na H antiporter
WL1483_RS08830	COG2951	lytic endotransglycosylase activity
WL1483_RS08835	COG0140	phosphoribosyl-ATP diphosphatase activity
WL1483_RS08835	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
WL1483_RS08840	COG0107	imidazoleglycerol-phosphate synthase activity
WL1483_RS08845	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
WL1483_RS08850	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
WL1483_RS08855	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
WL1483_RS08855	COG0131	Imidazoleglycerol-phosphate dehydratase
WL1483_RS08860	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
WL1483_RS08865	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
WL1483_RS08870	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
WL1483_RS08880	COG1199	ATP-dependent helicase activity
WL1483_RS08885	COG1214	PFAM Peptidase M22, glycoprotease
WL1483_RS08890	COG3065	identical protein binding
WL1483_RS08900	COG0318	PFAM AMP-dependent synthetase and ligase
WL1483_RS08905	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
WL1483_RS08920	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
WL1483_RS08925	COG2832	Protein of unknown function (DUF454)
WL1483_RS08930	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
WL1483_RS08935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
WL1483_RS08940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
WL1483_RS08945	COG2801	Transposase and inactivated derivatives
WL1483_RS08960	COG0753	catalase activity
WL1483_RS08995	COG0582	viral genome integration into host DNA
WL1483_RS09000	COG2801	Transposase and inactivated derivatives
WL1483_RS09025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
WL1483_RS09035	COG0391	Required for morphogenesis under gluconeogenic growth conditions
WL1483_RS09045	COG0784	Response regulator, receiver
WL1483_RS09045	COG2198	Histidine kinase
WL1483_RS09045	COG5002	protein histidine kinase activity
WL1483_RS09055	COG2197	response regulator
WL1483_RS09060	COG3850	Histidine kinase
WL1483_RS09065	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
WL1483_RS09080	COG0243	molybdopterin cofactor binding
WL1483_RS09085	COG0437	4 iron, 4 sulfur cluster binding
WL1483_RS09090	COG0348	domain, Protein
WL1483_RS09095	COG3043	anaerobic respiration
WL1483_RS09100	COG3005	denitrification pathway
WL1483_RS09105	COG0521	Mo-molybdopterin cofactor biosynthetic process
WL1483_RS09110	COG0315	cyclic pyranopterin monophosphate synthase activity
WL1483_RS09115	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
WL1483_RS09120	COG0314	molybdopterin synthase activity
WL1483_RS09135	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
WL1483_RS09140	COG2267	carboxylic ester hydrolase activity
WL1483_RS09150	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WL1483_RS09155	COG0303	'Molybdopterin
WL1483_RS09160	COG0302	gtp cyclohydrolase
WL1483_RS09165	COG0840	transmembrane signaling receptor activity
WL1483_RS09170	COG2759	Belongs to the formate--tetrahydrofolate ligase family
WL1483_RS09180	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
WL1483_RS09205	COG1609	Transcriptional regulator
WL1483_RS09210	COG1263	PTS System
WL1483_RS09210	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WL1483_RS09215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
WL1483_RS09230	COG4792	protein secretion
WL1483_RS09235	COG4791	protein targeting
WL1483_RS09240	COG4794	Type iii secretion
WL1483_RS09245	COG4790	Type iii secretion
WL1483_RS09290	COG0457	Tetratricopeptide repeat
WL1483_RS09405	COG1317	bacterial-type flagellum organization
WL1483_RS09415	COG3135	benzoate transporter
WL1483_RS09420	COG1396	sequence-specific DNA binding
WL1483_RS09495	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
WL1483_RS09505	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
WL1483_RS09515	COG0724	RNA recognition motif
WL1483_RS09520	COG4989	oxidoreductase activity
WL1483_RS09525	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
WL1483_RS09530	COG0437	4 iron, 4 sulfur cluster binding
WL1483_RS09535	COG5557	Pfam Polysulphide reductase, NrfD
WL1483_RS09540	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
WL1483_RS09545	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
WL1483_RS09550	COG1773	rubredoxin
WL1483_RS09555	COG0747	negative chemotaxis
WL1483_RS09560	COG0601	transmembrane transport
WL1483_RS09565	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
WL1483_RS09580	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
WL1483_RS09585	COG0375	protein maturation
WL1483_RS09590	COG0309	Hydrogenase expression formation protein (HypE)
WL1483_RS09600	COG0298	carbon dioxide binding
WL1483_RS09605	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
WL1483_RS09615	COG1921	L-seryl-tRNASec selenium transferase activity
WL1483_RS09650	COG3007	enoyl-[acyl-carrier-protein] reductase (NADH) activity
WL1483_RS09655	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
WL1483_RS09675	COG2979	Protein of unknown function (DUF533)
WL1483_RS09690	COG1595	DNA-templated transcription, initiation
WL1483_RS09705	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WL1483_RS09710	COG1271	oxidase subunit
WL1483_RS09715	COG1294	oxidase, subunit
WL1483_RS09735	COG3220	belongs to the UPF0276 family
WL1483_RS09750	COG2249	NAD(P)H dehydrogenase (quinone) activity
WL1483_RS09760	COG0733	neurotransmitter:sodium symporter activity
WL1483_RS09770	COG1595	DNA-templated transcription, initiation
WL1483_RS09800	COG0714	Associated with various cellular activities
WL1483_RS09805	COG0183	Belongs to the thiolase family
WL1483_RS09810	COG1024	Enoyl-CoA hydratase
WL1483_RS09810	COG1250	3-hydroxyacyl-CoA dehydrogenase
WL1483_RS09815	COG4681	YaeQ
WL1483_RS09820	COG2932	Transcriptional regulator
WL1483_RS09895	COG2801	Transposase and inactivated derivatives
WL1483_RS09925	COG5433	transposase activity
WL1483_RS09960	COG0586	Pfam SNARE associated Golgi protein
WL1483_RS09965	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WL1483_RS09970	COG0583	DNA-binding transcription factor activity
WL1483_RS09975	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
WL1483_RS09995	COG0583	DNA-binding transcription factor activity
WL1483_RS10010	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
WL1483_RS10015	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
WL1483_RS10015	COG0574	Belongs to the PEP-utilizing enzyme family
WL1483_RS10020	COG1404	Belongs to the peptidase S8 family
WL1483_RS10025	COG2824	Alkylphosphonate utilization operon protein PhnA
WL1483_RS10040	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL1483_RS10050	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
WL1483_RS10085	COG0861	Integral membrane protein TerC family
WL1483_RS10115	COG2119	membrane
WL1483_RS10120	COG0023	Translation Initiation Factor
WL1483_RS10155	COG4139	cobalamin transport
WL1483_RS10160	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
WL1483_RS10165	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WL1483_RS10170	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
WL1483_RS10175	COG0544	peptidyl-prolyl cis-trans isomerase activity
WL1483_RS10180	COG0740	serine-type endopeptidase activity
WL1483_RS10185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
WL1483_RS10190	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
WL1483_RS10195	COG0776	regulation of translation
WL1483_RS10200	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WL1483_RS10205	COG4166	transmembrane transport
WL1483_RS10210	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
WL1483_RS10230	COG0814	amino acid
WL1483_RS10235	COG1609	Transcriptional regulator
WL1483_RS10245	COG1105	Belongs to the carbohydrate kinase PfkB family
WL1483_RS10250	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WL1483_RS10250	COG3925	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity
WL1483_RS10250	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
WL1483_RS10255	COG3313	Fe-S protein
WL1483_RS10260	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
WL1483_RS10280	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
WL1483_RS10305	COG0205	6-phosphofructokinase activity
WL1483_RS10315	COG1434	Gram-negative-bacterium-type cell wall biogenesis
WL1483_RS10320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WL1483_RS10330	COG3095	Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF
WL1483_RS10340	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WL1483_RS10355	COG0537	adenosine 5'-monophosphoramidase activity
WL1483_RS10360	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
WL1483_RS10380	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WL1483_RS10385	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
WL1483_RS10415	COG1252	NADH dehydrogenase
WL1483_RS10420	COG0393	Putative heavy-metal-binding
WL1483_RS10425	COG1619	proteins homologs of microcin C7 resistance protein MccF
WL1483_RS10430	COG0604	alcohol dehydrogenase
WL1483_RS10450	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
WL1483_RS10465	COG0567	Dehydrogenase, E1 component
WL1483_RS10470	COG0508	dehydrogenase complex catalyzes the overall conversion of
WL1483_RS10475	COG0045	succinate-CoA ligase (ADP-forming) activity
WL1483_RS10490	COG2801	Transposase and inactivated derivatives
WL1483_RS10495	COG0697	spore germination
WL1483_RS10500	COG2801	Transposase and inactivated derivatives
WL1483_RS10510	COG1760	l-serine dehydratase
WL1483_RS10520	COG1451	nucleotide metabolic process
WL1483_RS10535	COG3069	C4-dicarboxylate transmembrane transporter activity
WL1483_RS10545	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
WL1483_RS10545	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
WL1483_RS10550	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WL1483_RS10560	COG3123	guanosine phosphorylase activity
WL1483_RS10565	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WL1483_RS10570	COG0840	transmembrane signaling receptor activity
WL1483_RS10575	COG1254	Belongs to the acylphosphatase family
WL1483_RS10585	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WL1483_RS10585	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WL1483_RS10590	COG0489	protein tyrosine kinase activity
WL1483_RS10595	COG0572	uridine kinase
WL1483_RS10600	COG0717	Belongs to the dCTP deaminase family
WL1483_RS10605	COG0306	phosphate transporter
WL1483_RS10615	COG1530	ribonuclease E activity
WL1483_RS10625	COG0564	pseudouridine synthase activity
WL1483_RS10630	COG3397	chitin binding
WL1483_RS10640	COG1399	metal-binding, possibly nucleic acid-binding protein
WL1483_RS10645	COG0333	Belongs to the bacterial ribosomal protein bL32 family
WL1483_RS10650	COG0416	fatty acid biosynthetic process
WL1483_RS10655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
WL1483_RS10675	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WL1483_RS10680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
WL1483_RS10685	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
WL1483_RS10690	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
WL1483_RS10695	COG0470	DNA polymerase III
WL1483_RS10700	COG0084	hydrolase, TatD family'
WL1483_RS10720	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
WL1483_RS10720	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WL1483_RS10730	COG3008	intermembrane lipid transfer
WL1483_RS10735	COG2995	paraquat-inducible protein a
WL1483_RS10745	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
WL1483_RS10750	COG0372	Belongs to the citrate synthase family
WL1483_RS10800	COG1309	transcriptional regulator
WL1483_RS10815	COG4221	oxidoreductase activity
WL1483_RS10820	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
WL1483_RS10845	COG1366	Belongs to the anti-sigma-factor antagonist family
WL1483_RS10855	COG5002	protein histidine kinase activity
WL1483_RS10855	COG2205	protein histidine kinase activity
WL1483_RS10855	COG0784	Response regulator, receiver
WL1483_RS10860	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
WL1483_RS10870	COG0297	glycogen (starch) synthase activity
WL1483_RS10910	COG0110	maltose O-acetyltransferase activity
WL1483_RS10930	COG0438	transferase activity, transferring glycosyl groups
WL1483_RS10940	COG3141	response to X-ray
WL1483_RS10955	COG2801	Transposase and inactivated derivatives
WL1483_RS10985	COG1067	ATP-dependent peptidase activity
WL1483_RS10990	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WL1483_RS10995	COG0488	(ABC) transporter
WL1483_RS11005	COG0116	Belongs to the methyltransferase superfamily
WL1483_RS11005	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
WL1483_RS11015	COG0167	dihydroorotate dehydrogenase activity
WL1483_RS11020	COG2902	Dehydrogenase
WL1483_RS11030	COG0308	aminopeptidase N
WL1483_RS11050	COG1132	(ABC) transporter
WL1483_RS11055	COG1132	(ABC) transporter
WL1483_RS11060	COG3437	response regulator, receiver
WL1483_RS11060	COG3850	Histidine kinase
WL1483_RS11060	COG4999	Histidine kinase
WL1483_RS11060	COG2205	protein histidine kinase activity
WL1483_RS11070	COG3118	belongs to the thioredoxin family
WL1483_RS11075	COG0471	metal ion transport
WL1483_RS11085	COG3099	Belongs to the UPF0263 family
WL1483_RS11090	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WL1483_RS11125	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
WL1483_RS11130	COG0697	spore germination
WL1483_RS11135	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
WL1483_RS11140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
WL1483_RS11155	COG0307	riboflavin synthase, alpha
WL1483_RS11165	COG0534	Mate efflux family protein
WL1483_RS11200	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
WL1483_RS11205	COG2925	Exonuclease
WL1483_RS11215	COG3345	alpha-galactosidase
WL1483_RS11220	COG1380	Effector of murein hydrolase LrgA
WL1483_RS11225	COG1346	cytolysis
WL1483_RS11230	COG0295	cytidine deaminase activity
WL1483_RS11245	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
WL1483_RS11255	COG1869	D-ribose catabolic process
WL1483_RS11260	COG1129	ABC transporter
WL1483_RS11265	COG1172	Belongs to the binding-protein-dependent transport system permease family
WL1483_RS11270	COG1879	ABC-type sugar transport system periplasmic component
WL1483_RS11275	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL1483_RS11280	COG1609	Transcriptional regulator
WL1483_RS11285	COG2199	diguanylate cyclase activity
WL1483_RS11310	COG0784	Response regulator, receiver
WL1483_RS11310	COG2205	protein histidine kinase activity
WL1483_RS11315	COG0776	regulation of translation
WL1483_RS11320	COG0072	phenylalanine-tRNA ligase activity
WL1483_RS11320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
WL1483_RS11325	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
WL1483_RS11335	COG0058	SHG alpha-glucan phosphorylase activity
WL1483_RS11350	COG2067	long-chain fatty acid transport protein
WL1483_RS11355	COG2067	long-chain fatty acid transport protein
WL1483_RS11360	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
WL1483_RS11375	COG1301	dicarboxylic acid transport
WL1483_RS11380	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
WL1483_RS11390	COG2062	phosphohistidine phosphatase, SixA
WL1483_RS11400	COG0500	methyltransferase
WL1483_RS11430	COG0582	viral genome integration into host DNA
WL1483_RS11455	COG0582	viral genome integration into host DNA
WL1483_RS11460	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WL1483_RS11460	COG0519	Catalyzes the synthesis of GMP from XMP
WL1483_RS11465	COG0517	IMP dehydrogenase activity
WL1483_RS11465	COG0516	GMP reductase activity
WL1483_RS11500	COG0494	nUDIX hydrolase
WL1483_RS11505	COG0814	amino acid
WL1483_RS11510	COG1760	l-serine dehydratase
WL1483_RS11530	COG0709	Synthesizes selenophosphate from selenide and ATP
WL1483_RS11535	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
WL1483_RS11540	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WL1483_RS11545	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
WL1483_RS11555	COG1643	Atp-dependent helicase
WL1483_RS11560	COG0517	IMP dehydrogenase activity
WL1483_RS11560	COG0516	GMP reductase activity
WL1483_RS11595	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WL1483_RS11630	COG3593	DNA synthesis involved in DNA repair
WL1483_RS11645	COG0583	DNA-binding transcription factor activity
WL1483_RS11650	COG0730	response to heat
WL1483_RS11655	COG3148	PFAM DTW domain containing protein
WL1483_RS11665	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WL1483_RS11670	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WL1483_RS11675	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
WL1483_RS11685	COG0793	Belongs to the peptidase S41A family
WL1483_RS11690	COG3109	RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities
WL1483_RS11695	COG1956	GAF domain-containing protein
WL1483_RS11705	COG3278	Belongs to the heme-copper respiratory oxidase family
WL1483_RS11720	COG2010	Cytochrome c
WL1483_RS11745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WL1483_RS11750	COG0589	response to stress
WL1483_RS11755	COG0037	tRNA processing
WL1483_RS11780	COG1177	transmembrane transport
WL1483_RS11790	COG1181	Belongs to the D-alanine--D-alanine ligase family
WL1483_RS11800	COG0386	Belongs to the glutathione peroxidase family
WL1483_RS11805	COG0513	Belongs to the DEAD box helicase family
WL1483_RS11815	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WL1483_RS11820	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
WL1483_RS11825	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
WL1483_RS11860	COG0556	nucleotide-excision repair
WL1483_RS11870	COG0513	Belongs to the DEAD box helicase family
WL1483_RS11880	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
WL1483_RS11885	COG2890	protein-(glutamine-N5) methyltransferase activity
WL1483_RS11890	COG2840	Smr protein MutS2
WL1483_RS11895	COG3706	GGDEF domain
WL1483_RS11905	COG1505	serine-type exopeptidase activity
WL1483_RS11920	COG2985	domain, Protein
WL1483_RS11920	COG0569	domain protein
WL1483_RS11925	COG1022	Amp-dependent synthetase and ligase
WL1483_RS11940	COG1166	arginine decarboxylase activity
WL1483_RS11950	COG2195	Cleaves the N-terminal amino acid of tripeptides
WL1483_RS11955	COG2885	chlorophyll binding
WL1483_RS11960	COG3706	GGDEF domain
WL1483_RS11975	COG2154	pterin-4-alpha-carbinolamine dehydratase
WL1483_RS11985	COG3768	UPF0283 membrane protein
WL1483_RS11990	COG3106	COG3106 Predicted ATPase
WL1483_RS12005	COG1842	Phage shock protein A
WL1483_RS12010	COG1221	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain
WL1483_RS12015	COG4166	transmembrane transport
WL1483_RS12020	COG4168	peptide transport system, permease
WL1483_RS12025	COG4171	peptide transport system, permease
WL1483_RS12035	COG4172	Belongs to the ABC transporter superfamily
WL1483_RS12045	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
WL1483_RS12050	COG1286	toxin biosynthetic process
WL1483_RS12055	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
WL1483_RS12060	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
WL1483_RS12065	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
WL1483_RS12070	COG0531	amino acid
WL1483_RS12070	COG1674	ftsk spoiiie
WL1483_RS12080	COG0686	Belongs to the AlaDH PNT family
WL1483_RS12100	COG2723	6-phospho-beta-galactosidase activity
WL1483_RS12105	COG0583	DNA-binding transcription factor activity
WL1483_RS12115	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
WL1483_RS12130	COG2801	Transposase and inactivated derivatives
WL1483_RS12180	COG0322	excinuclease ABC activity
WL1483_RS12185	COG2197	response regulator
WL1483_RS12190	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
WL1483_RS12195	COG2835	tetraacyldisaccharide 4'-kinase activity
WL1483_RS12200	COG1663	tetraacyldisaccharide 4'-kinase activity
WL1483_RS12205	COG1132	(ABC) transporter
WL1483_RS12225	COG0670	Belongs to the BI1 family
WL1483_RS12230	COG1289	transmembrane transporter activity
WL1483_RS12235	COG2920	part of a sulfur-relay system
WL1483_RS12240	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
WL1483_RS12245	COG0285	dihydrofolate synthase activity
WL1483_RS12250	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
WL1483_RS12255	COG0101	tRNA pseudouridine synthase activity
WL1483_RS12265	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WL1483_RS12270	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
WL1483_RS12275	COG0671	phosphoesterase, PA-phosphatase related
WL1483_RS12280	COG0492	ferredoxin-NADP+ reductase activity
WL1483_RS12285	COG3706	GGDEF domain
WL1483_RS12290	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
WL1483_RS12295	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
WL1483_RS12300	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
WL1483_RS12305	COG0542	response to heat
WL1483_RS12310	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
WL1483_RS12315	COG1278	Cold shock
WL1483_RS12320	COG0697	spore germination
WL1483_RS12325	COG3134	Outer membrane lipoprotein
WL1483_RS12335	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
WL1483_RS12340	COG0647	UMP catabolic process
WL1483_RS12345	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WL1483_RS12345	COG4651	solute:proton antiporter activity
WL1483_RS12355	COG0367	asparagine synthase
WL1483_RS12365	COG0642	Histidine kinase
WL1483_RS12400	COG0697	spore germination
WL1483_RS12405	COG4657	Part of a membrane complex involved in electron transport
WL1483_RS12410	COG2878	Part of a membrane complex involved in electron transport
WL1483_RS12420	COG4658	electron transport chain
WL1483_RS12425	COG4659	FMN binding
WL1483_RS12430	COG4660	Part of a membrane complex involved in electron transport
WL1483_RS12435	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
WL1483_RS12440	COG0346	lactoylglutathione lyase activity
WL1483_RS12455	COG0704	Plays a role in the regulation of phosphate uptake
WL1483_RS12460	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
WL1483_RS12465	COG0581	inorganic phosphate transmembrane transporter activity
WL1483_RS12525	COG2771	luxR family
WL1483_RS12525	COG2200	EAL domain
WL1483_RS12560	COG2801	Transposase and inactivated derivatives
WL1483_RS12570	COG0019	diaminopimelate decarboxylase activity
WL1483_RS12600	COG4772	TonB-dependent receptor
WL1483_RS12605	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
WL1483_RS12610	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WL1483_RS12615	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WL1483_RS12620	COG1120	ATPase activity
WL1483_RS12635	COG3415	Transposase
WL1483_RS12635	COG2801	Transposase and inactivated derivatives
WL1483_RS12650	COG2801	Transposase and inactivated derivatives
WL1483_RS12690	COG2003	Belongs to the UPF0758 family
WL1483_RS12765	COG2801	Transposase and inactivated derivatives
WL1483_RS12800	COG1785	Belongs to the alkaline phosphatase family
WL1483_RS12820	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WL1483_RS12825	COG2197	response regulator
WL1483_RS12860	COG2050	protein possibly involved in aromatic compounds catabolism
WL1483_RS12870	COG0247	lactate metabolic process
WL1483_RS12870	COG0277	FAD linked oxidase domain protein
WL1483_RS12880	COG3568	Endonuclease Exonuclease Phosphatase
WL1483_RS12890	COG1902	pentaerythritol trinitrate reductase activity
WL1483_RS12895	COG0583	DNA-binding transcription factor activity
WL1483_RS12900	COG1566	PFAM secretion protein HlyD family protein
WL1483_RS12910	COG3214	Protein conserved in bacteria
WL1483_RS12920	COG2801	Transposase and inactivated derivatives
WL1483_RS12960	COG0730	response to heat
WL1483_RS12970	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS12980	COG1024	Enoyl-CoA hydratase
WL1483_RS12985	COG1024	Enoyl-CoA hydratase
WL1483_RS12990	COG1960	acyl-CoA dehydrogenase activity
WL1483_RS13000	COG1960	acyl-CoA dehydrogenase activity
WL1483_RS13005	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
WL1483_RS13015	COG4770	biotin carboxylase activity
WL1483_RS13040	COG1584	GPR1 FUN34 yaaH family protein
WL1483_RS13045	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
WL1483_RS13055	COG1944	ATP diphosphatase activity
WL1483_RS13060	COG2116	formate transmembrane transporter activity
WL1483_RS13065	COG1882	Formate acetyltransferase
WL1483_RS13080	COG0577	efflux transmembrane transporter activity
WL1483_RS13110	COG5002	protein histidine kinase activity
WL1483_RS13115	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
WL1483_RS13135	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WL1483_RS13145	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
WL1483_RS13145	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
WL1483_RS13150	COG0527	aspartate kinase activity
WL1483_RS13160	COG3012	SEC-C Motif Domain Protein
WL1483_RS13170	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
WL1483_RS13175	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
WL1483_RS13180	COG0247	lactate metabolic process
WL1483_RS13195	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
WL1483_RS13200	COG0437	4 iron, 4 sulfur cluster binding
WL1483_RS13205	COG3301	Polysulphide reductase, NrfD
WL1483_RS13210	COG1138	Cytochrome C-type biogenesis protein
WL1483_RS13215	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
WL1483_RS13220	COG4235	cytochrome complex assembly
WL1483_RS13220	COG3088	subunit of a heme lyase
WL1483_RS13235	COG0417	DNA replication proofreading
WL1483_RS13240	COG2199	diguanylate cyclase activity
WL1483_RS13240	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WL1483_RS13260	COG0840	transmembrane signaling receptor activity
WL1483_RS13265	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL1483_RS13275	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
WL1483_RS13280	COG0563	adenylate kinase activity
WL1483_RS13285	COG0326	Molecular chaperone. Has ATPase activity
WL1483_RS13290	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
WL1483_RS13300	COG2801	Transposase and inactivated derivatives
WL1483_RS13435	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WL1483_RS13470	COG3385	transposase activity
WL1483_RS13475	COG1450	Type ii and iii secretion system protein
WL1483_RS13510	COG2165	general secretion pathway protein
WL1483_RS13520	COG1459	type II secretion system
WL1483_RS13540	COG1091	dTDP-4-dehydrorhamnose reductase activity
WL1483_RS13550	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WL1483_RS13550	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
WL1483_RS13555	COG0509	glycine decarboxylation via glycine cleavage system
WL1483_RS13560	COG0404	The glycine cleavage system catalyzes the degradation of glycine
WL1483_RS13565	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WL1483_RS13570	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WL1483_RS13580	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
WL1483_RS13590	COG2814	Major facilitator Superfamily
WL1483_RS13595	COG0483	inositol monophosphate 1-phosphatase activity
WL1483_RS13600	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
WL1483_RS13620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
WL1483_RS13625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
WL1483_RS13630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
WL1483_RS13635	COG0121	glutamine amidotransferase
WL1483_RS13640	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WL1483_RS13655	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WL1483_RS13660	COG0328	RNA-DNA hybrid ribonuclease activity
WL1483_RS13665	COG2226	methyltransferase
WL1483_RS13670	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
WL1483_RS13675	COG0741	lytic transglycosylase activity
WL1483_RS13675	COG1388	LysM domain
WL1483_RS13690	COG1607	acyl-coa hydrolase
WL1483_RS13695	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WL1483_RS13715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
WL1483_RS13730	COG2911	Protein conserved in bacteria
WL1483_RS13745	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
WL1483_RS13765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
WL1483_RS13770	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WL1483_RS13775	COG4134	Bacterial extracellular solute-binding protein
WL1483_RS13780	COG4135	transport system, permease component
WL1483_RS13785	COG4136	ATPase activity
WL1483_RS13790	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
WL1483_RS13800	COG3634	alkyl hydroperoxide reductase activity
WL1483_RS13805	COG0837	glucose binding
WL1483_RS13810	COG1737	Transcriptional regulator
WL1483_RS13815	COG0469	pyruvate kinase activity
WL1483_RS13830	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
WL1483_RS13850	COG2801	Transposase and inactivated derivatives
WL1483_RS13865	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WL1483_RS13905	COG0109	protoheme IX farnesyltransferase activity
WL1483_RS13915	COG0009	L-threonylcarbamoyladenylate synthase
WL1483_RS13925	COG2814	Major facilitator Superfamily
WL1483_RS13945	COG1355	regulation of microtubule-based process
WL1483_RS13955	COG1846	Transcriptional regulator
WL1483_RS13955	COG1940	carbohydrate kinase activity
WL1483_RS13965	COG0784	Response regulator, receiver
WL1483_RS13965	COG3437	response regulator, receiver
WL1483_RS13975	COG1199	ATP-dependent helicase activity
WL1483_RS13980	COG3110	Uncharacterized protein conserved in bacteria (DUF2057)
WL1483_RS13985	COG0123	including yeast histone deacetylase and acetoin utilization protein
WL1483_RS13990	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
WL1483_RS14000	COG1253	flavin adenine dinucleotide binding
WL1483_RS14005	COG2885	chlorophyll binding
WL1483_RS14010	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
WL1483_RS14020	COG0659	secondary active sulfate transmembrane transporter activity
WL1483_RS14045	COG2801	Transposase and inactivated derivatives
WL1483_RS14050	COG2801	Transposase and inactivated derivatives
WL1483_RS14070	COG1115	amino acid carrier protein
WL1483_RS14075	COG1024	Enoyl-CoA hydratase
WL1483_RS14090	COG3162	membrane
WL1483_RS14095	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WL1483_RS14100	COG0488	(ABC) transporter
WL1483_RS14105	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
WL1483_RS14110	COG0291	Belongs to the bacterial ribosomal protein bL35 family
WL1483_RS14115	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
WL1483_RS14120	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
WL1483_RS14135	COG2766	serine protein kinase
WL1483_RS14140	COG2718	Belongs to the UPF0229 family
WL1483_RS14145	COG2719	SpoVR family
WL1483_RS14150	COG2186	Transcriptional regulator
WL1483_RS14155	COG3067	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
WL1483_RS14160	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
WL1483_RS14165	COG2983	Belongs to the UPF0260 family
WL1483_RS14170	COG3100	YcgL domain-containing protein
WL1483_RS14175	COG0850	regulation of cytokinetic process
WL1483_RS14180	COG2894	cell division
WL1483_RS14185	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
WL1483_RS14195	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
WL1483_RS14200	COG4591	ABC-type transport system involved in lipoprotein release permease component
WL1483_RS14205	COG1136	(ABC) transporter
WL1483_RS14210	COG4591	ABC-type transport system involved in lipoprotein release permease component
WL1483_RS14220	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
WL1483_RS14225	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
WL1483_RS14235	COG4771	TonB-dependent receptor
WL1483_RS14240	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WL1483_RS14245	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WL1483_RS14250	COG1120	ATPase activity
WL1483_RS14255	COG2977	Belongs to the P-Pant transferase superfamily
WL1483_RS14260	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
WL1483_RS14265	COG3321	synthase
WL1483_RS14265	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS14265	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WL1483_RS14265	COG0318	PFAM AMP-dependent synthetase and ligase
WL1483_RS14265	COG0300	oxidoreductase activity
WL1483_RS14275	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS14280	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
WL1483_RS14285	COG3433	isochorismatase activity
WL1483_RS14285	COG1535	isochorismatase
WL1483_RS14290	COG1021	2,3-dihydroxybenzoate-AMP ligase
WL1483_RS14300	COG2375	cellular response to nickel ion
WL1483_RS14305	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
WL1483_RS14340	COG3171	Protein conserved in bacteria
WL1483_RS14355	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
WL1483_RS14365	COG0732	type I restriction modification DNA specificity domain
WL1483_RS14385	COG1715	Restriction endonuclease
WL1483_RS14395	COG2801	Transposase and inactivated derivatives
WL1483_RS14405	COG2252	PERMEase
WL1483_RS14410	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WL1483_RS14415	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WL1483_RS14420	COG2080	2 iron, 2 sulfur cluster binding
WL1483_RS14425	COG3829	transcription factor binding
WL1483_RS14435	COG2801	Transposase and inactivated derivatives
WL1483_RS14450	COG2801	Transposase and inactivated derivatives
WL1483_RS14460	COG2252	PERMEase
WL1483_RS14465	COG0402	S-adenosylhomocysteine deaminase activity
WL1483_RS14470	COG2233	PERMEase
WL1483_RS14475	COG1529	Aldehyde oxidase and xanthine dehydrogenase
WL1483_RS14475	COG2080	2 iron, 2 sulfur cluster binding
WL1483_RS14480	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
WL1483_RS14485	COG0402	S-adenosylhomocysteine deaminase activity
WL1483_RS14490	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WL1483_RS14490	COG0493	'glutamate synthase
WL1483_RS14500	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WL1483_RS14505	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
WL1483_RS14505	COG3608	succinylglutamate desuccinylase aspartoacylase
WL1483_RS14540	COG4104	PAAR repeat-containing protein
WL1483_RS14555	COG0697	spore germination
WL1483_RS14560	COG0549	Belongs to the carbamate kinase family
WL1483_RS14570	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
WL1483_RS14575	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
WL1483_RS14580	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WL1483_RS14585	COG0814	amino acid
WL1483_RS14590	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
WL1483_RS14595	COG1982	Orn Lys Arg decarboxylase major
WL1483_RS14600	COG0531	amino acid
WL1483_RS14605	COG3710	Transcriptional regulator
WL1483_RS14620	COG0825	malonyl-CoA metabolic process
WL1483_RS14625	COG0587	DNA-directed DNA polymerase activity
WL1483_RS14630	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
WL1483_RS14635	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL1483_RS14640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL1483_RS14645	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WL1483_RS14650	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
WL1483_RS14665	COG0750	zinc metalloprotease
WL1483_RS14670	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
WL1483_RS14675	COG0575	Belongs to the CDS family
WL1483_RS14680	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
WL1483_RS14685	COG0233	cytoplasmic translational termination
WL1483_RS14690	COG0528	UMP kinase activity
WL1483_RS14695	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
WL1483_RS14700	COG0052	Belongs to the universal ribosomal protein uS2 family
WL1483_RS14705	COG0024	Methionine aminopeptidase
WL1483_RS14715	COG2171	N-acyltransferase activity
WL1483_RS14725	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WL1483_RS14725	COG1263	PTS System
WL1483_RS14735	COG4580	involved in the transport of maltose and maltodextrins
WL1483_RS14775	COG0419	ATPase involved in DNA repair
WL1483_RS14780	COG0420	3'-5' exonuclease activity
WL1483_RS14790	COG2974	May be involved in recombination
WL1483_RS14795	COG4651	solute:proton antiporter activity
WL1483_RS14795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
WL1483_RS14800	COG0405	Gamma-glutamyltransferase
WL1483_RS14815	COG0583	DNA-binding transcription factor activity
WL1483_RS14835	COG0583	DNA-binding transcription factor activity
WL1483_RS14840	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS14875	COG0813	purine-nucleoside phosphorylase activity
WL1483_RS14890	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
WL1483_RS14895	COG0083	homoserine kinase activity
WL1483_RS14905	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
WL1483_RS14910	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
WL1483_RS14915	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
WL1483_RS14925	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
WL1483_RS14930	COG0511	ligase activity, forming carbon-carbon bonds
WL1483_RS14935	COG0439	Biotin carboxylase
WL1483_RS14940	COG3924	membrane
WL1483_RS14945	COG4145	pantothenate transmembrane transporter activity
WL1483_RS14950	COG1263	PTS System
WL1483_RS14950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
WL1483_RS14955	COG0583	DNA-binding transcription factor activity
WL1483_RS14965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
WL1483_RS14975	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
WL1483_RS14980	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
WL1483_RS14985	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
WL1483_RS14990	COG3366	ferrous iron transmembrane transporter activity
WL1483_RS14995	COG0700	Nucleoside recognition
WL1483_RS15025	COG0842	Transport permease protein
WL1483_RS15030	COG1131	(ABC) transporter
WL1483_RS15045	COG3005	denitrification pathway
WL1483_RS15050	COG2863	cytochrome
WL1483_RS15070	COG0163	prenyltransferase activity
WL1483_RS15075	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WL1483_RS15080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
WL1483_RS15110	COG1136	(ABC) transporter
WL1483_RS15115	COG0577	efflux transmembrane transporter activity
WL1483_RS15130	COG1560	Kdo2-lipid A biosynthetic process
WL1483_RS15160	COG2801	Transposase and inactivated derivatives
WL1483_RS15175	COG0529	Catalyzes the synthesis of activated sulfate
WL1483_RS15180	COG3273	potassium ion transport
WL1483_RS15180	COG0471	metal ion transport
WL1483_RS15185	COG2895	sulfate adenylyltransferase (ATP) activity
WL1483_RS15190	COG0175	sulfate reduction
WL1483_RS15195	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WL1483_RS15195	COG1648	precorrin-2 dehydrogenase activity
WL1483_RS15205	COG2146	nitrite reductase [NAD(P)H] activity
WL1483_RS15205	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WL1483_RS15210	COG1116	anion transmembrane transporter activity
WL1483_RS15215	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
WL1483_RS15220	COG1116	anion transmembrane transporter activity
WL1483_RS15220	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
WL1483_RS15235	COG0330	HflC and HflK could
WL1483_RS15240	COG1585	Membrane protein implicated in regulation of membrane protease activity
WL1483_RS15250	COG0488	(ABC) transporter
WL1483_RS15260	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
WL1483_RS15270	COG2801	Transposase and inactivated derivatives
WL1483_RS15280	COG1288	antiporter activity
WL1483_RS15305	COG0668	transmembrane transport
WL1483_RS15345	COG0346	lactoylglutathione lyase activity
WL1483_RS15360	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
WL1483_RS15375	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WL1483_RS15380	COG1335	isochorismatase
WL1483_RS15385	COG0583	DNA-binding transcription factor activity
WL1483_RS15395	COG4269	membrane
WL1483_RS15405	COG3152	Membrane
WL1483_RS15410	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
WL1483_RS15415	COG2814	Major facilitator Superfamily
WL1483_RS15420	COG0109	protoheme IX farnesyltransferase activity
WL1483_RS15425	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
WL1483_RS15430	COG1845	cytochrome c oxidase, subunit III
WL1483_RS15435	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
WL1483_RS15440	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
WL1483_RS15455	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
WL1483_RS15460	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WL1483_RS15465	COG2211	Major facilitator Superfamily
WL1483_RS15505	COG0826	peptidase U32
WL1483_RS15510	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WL1483_RS15525	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WL1483_RS15530	COG1136	(ABC) transporter
WL1483_RS15530	COG0577	efflux transmembrane transporter activity
WL1483_RS15545	COG0671	phosphoesterase, PA-phosphatase related
WL1483_RS15555	COG3437	response regulator, receiver
WL1483_RS15555	COG0784	Response regulator, receiver
WL1483_RS15560	COG0346	lactoylglutathione lyase activity
WL1483_RS15565	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
WL1483_RS15570	COG1643	Atp-dependent helicase
WL1483_RS15580	COG1489	DNA binding
WL1483_RS15585	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
WL1483_RS15590	COG2264	protein methyltransferase activity
WL1483_RS15615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WL1483_RS15630	COG2901	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters
WL1483_RS15645	COG1139	Iron-sulfur cluster binding protein
WL1483_RS15650	COG0247	lactate metabolic process
WL1483_RS15655	COG1620	l-lactate permease
WL1483_RS15660	COG0583	DNA-binding transcription factor activity
WL1483_RS15700	COG0316	Belongs to the HesB IscA family
WL1483_RS15710	COG0038	chloride channel
WL1483_RS15715	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
WL1483_RS15720	COG3314	Sporulation integral membrane protein YlbJ
WL1483_RS15725	COG3591	Belongs to the peptidase S1B family
WL1483_RS15735	COG1946	Acyl-CoA thioesterase
WL1483_RS15740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
WL1483_RS15750	COG1522	sequence-specific DNA binding
WL1483_RS15755	COG0778	Nitroreductase
WL1483_RS15760	COG1902	pentaerythritol trinitrate reductase activity
WL1483_RS15760	COG0446	pyridine nucleotide-disulphide oxidoreductase
WL1483_RS15765	COG0616	signal peptide processing
WL1483_RS15770	COG0786	glutamate:sodium symporter activity
WL1483_RS15775	COG0252	asparaginase activity
WL1483_RS15780	COG3139	Protein of unknown function (DUF1315)
WL1483_RS15795	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
WL1483_RS15805	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
WL1483_RS15810	COG1640	4-alpha-glucanotransferase
WL1483_RS15815	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
WL1483_RS15825	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
WL1483_RS15875	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
WL1483_RS15880	COG2885	chlorophyll binding
WL1483_RS15885	COG0823	Involved in the tonB-independent uptake of proteins
WL1483_RS15900	COG0811	peptide transport
WL1483_RS15905	COG0824	Thioesterase
WL1483_RS15910	COG3790	cyd operon protein YbgE
WL1483_RS15915	COG4890	Cyd operon protein YbgT
WL1483_RS15920	COG1294	oxidase, subunit
WL1483_RS15935	COG2255	four-way junction helicase activity
WL1483_RS15940	COG0632	four-way junction helicase activity
WL1483_RS15945	COG0840	transmembrane signaling receptor activity
WL1483_RS15950	COG0442	prolyl-tRNA aminoacylation
WL1483_RS15970	COG2202	Pas domain
WL1483_RS15970	COG2205	protein histidine kinase activity
WL1483_RS15980	COG3655	Transcriptional regulator
WL1483_RS15990	COG2814	Major facilitator Superfamily
WL1483_RS15995	COG4771	TonB-dependent receptor
WL1483_RS16015	COG0748	coenzyme F420 binding
WL1483_RS16020	COG3721	Heme iron utilization protein
WL1483_RS16030	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
WL1483_RS16060	COG2233	PERMEase
WL1483_RS16065	COG0488	(ABC) transporter
WL1483_RS16075	COG2252	PERMEase
WL1483_RS16085	COG0521	Mo-molybdopterin cofactor biosynthetic process
WL1483_RS16105	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
WL1483_RS16110	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS16155	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
WL1483_RS16160	COG0318	PFAM AMP-dependent synthetase and ligase
WL1483_RS16170	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WL1483_RS16175	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
WL1483_RS16195	COG2801	Transposase and inactivated derivatives
WL1483_RS16220	COG2313	pseudouridylate synthase activity
WL1483_RS16225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL1483_RS16235	COG0589	response to stress
WL1483_RS16240	COG2204	response regulator
WL1483_RS16260	COG0737	Belongs to the 5'-nucleotidase family
WL1483_RS16270	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
WL1483_RS16285	COG1073	alpha beta
WL1483_RS16290	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
WL1483_RS16295	COG2195	Cleaves the N-terminal amino acid of tripeptides
WL1483_RS16300	COG0602	queuosine metabolic process
WL1483_RS16305	COG1328	CTP reductase activity
WL1483_RS16315	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
WL1483_RS16320	COG3115	cell septum assembly
WL1483_RS16325	COG1196	nuclear chromosome segregation
WL1483_RS16335	COG2860	membrane
WL1483_RS16340	COG1803	Methylglyoxal synthase
WL1483_RS16350	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
WL1483_RS16355	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
WL1483_RS16360	COG1702	phosphate starvation-inducible protein PhoH
WL1483_RS16365	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
WL1483_RS16370	COG4535	Mg2 and Co2 transporter CorC
WL1483_RS16375	COG0815	Transfers the fatty acyl group on membrane lipoproteins
WL1483_RS16385	COG0495	leucyl-tRNA aminoacylation
WL1483_RS16395	COG1466	dna polymerase III delta subunit
WL1483_RS16400	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
WL1483_RS16405	COG0799	negative regulation of ribosome biogenesis
WL1483_RS16410	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
WL1483_RS16415	COG0768	penicillin binding
WL1483_RS16420	COG0772	Belongs to the SEDS family
WL1483_RS16425	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
WL1483_RS16430	COG1686	Belongs to the peptidase S11 family
WL1483_RS16435	COG2921	Belongs to the UPF0250 family
WL1483_RS16440	COG0321	lipoyl(octanoyl) transferase activity
WL1483_RS16445	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
WL1483_RS16455	COG2731	YhcH YjgK YiaL family protein
WL1483_RS16465	COG1794	racemase activity, acting on amino acids and derivatives
WL1483_RS16480	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WL1483_RS16520	COG0583	DNA-binding transcription factor activity
WL1483_RS16540	COG1511	domain protein
WL1483_RS16540	COG3264	Mechanosensitive ion channel
WL1483_RS16545	COG0584	glycerophosphoryl diester phosphodiesterase
WL1483_RS16555	COG1049	propionate catabolic process, 2-methylcitrate cycle
WL1483_RS16565	COG0840	transmembrane signaling receptor activity
WL1483_RS16580	COG3706	GGDEF domain
WL1483_RS16585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WL1483_RS16590	COG0508	dehydrogenase complex catalyzes the overall conversion of
WL1483_RS16595	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
WL1483_RS16620	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WL1483_RS16635	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WL1483_RS16640	COG1459	type II secretion system
WL1483_RS16655	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
WL1483_RS16660	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
WL1483_RS16665	COG0494	nUDIX hydrolase
WL1483_RS16670	COG0653	protein targeting
WL1483_RS16680	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
WL1483_RS16685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
WL1483_RS16690	COG0849	cell division
WL1483_RS16700	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
WL1483_RS16705	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
WL1483_RS16710	COG0772	Belongs to the SEDS family
WL1483_RS16720	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
WL1483_RS16725	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
WL1483_RS16730	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
WL1483_RS16735	COG0768	penicillin binding
WL1483_RS16740	COG3116	cell division
WL1483_RS16745	COG0275	rRNA processing
WL1483_RS16750	COG2001	Belongs to the MraZ family
WL1483_RS16760	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
WL1483_RS16765	COG3107	peptidoglycan biosynthetic process
WL1483_RS16770	COG0792	nuclease activity
WL1483_RS16775	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
WL1483_RS16780	COG2823	Periplasmic or secreted lipoprotein
WL1483_RS16785	COG2969	positive regulation of protein catabolic process
WL1483_RS16790	COG0625	glutathione transferase activity
WL1483_RS16795	COG2857	Cytochrome c1
WL1483_RS16800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
WL1483_RS16805	COG0723	plastoquinol--plastocyanin reductase activity
WL1483_RS16810	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
WL1483_RS16815	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
WL1483_RS16820	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
WL1483_RS16830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WL1483_RS16835	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
WL1483_RS16865	COG3964	amidohydrolase
WL1483_RS16885	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
WL1483_RS16890	COG1660	Displays ATPase and GTPase activities
WL1483_RS16895	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
WL1483_RS16905	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
WL1483_RS16910	COG1137	ATPase activity
WL1483_RS16915	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
WL1483_RS16920	COG3117	lipopolysaccharide transmembrane transporter activity
WL1483_RS16925	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
WL1483_RS16930	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
WL1483_RS16930	COG0517	IMP dehydrogenase activity
WL1483_RS16935	COG1127	ABC transporter
WL1483_RS16940	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
WL1483_RS16945	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WL1483_RS16950	COG2854	intermembrane phospholipid transfer
WL1483_RS16960	COG5007	Belongs to the BolA IbaG family
WL1483_RS16965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
WL1483_RS16970	COG0312	modulator of DNA gyrase
WL1483_RS16975	COG3028	Belongs to the UPF0307 family
WL1483_RS16985	COG0477	Major facilitator Superfamily
WL1483_RS17000	COG0359	binds to the 23S rRNA
WL1483_RS17005	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
WL1483_RS17010	COG0360	Binds together with S18 to 16S ribosomal RNA
WL1483_RS17015	COG1914	H( )-stimulated, divalent metal cation uptake system
WL1483_RS17025	COG0583	DNA-binding transcription factor activity
WL1483_RS17030	COG1028	Short-chain dehydrogenase reductase Sdr
WL1483_RS17035	COG2814	Major facilitator Superfamily
WL1483_RS17090	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
WL1483_RS17115	COG2801	Transposase and inactivated derivatives
WL1483_RS17120	COG5433	transposase activity
WL1483_RS17125	COG0557	exoribonuclease II activity
WL1483_RS17130	COG3706	GGDEF domain
WL1483_RS17135	COG1854	S-ribosylhomocysteine lyase activity
WL1483_RS17150	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
WL1483_RS17150	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WL1483_RS17180	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
WL1483_RS17190	COG2204	response regulator
WL1483_RS17200	COG2205	protein histidine kinase activity
WL1483_RS17255	COG1129	ABC transporter
WL1483_RS17255	COG0842	Transport permease protein
WL1483_RS17265	COG0513	Belongs to the DEAD box helicase family
WL1483_RS17280	COG0513	Belongs to the DEAD box helicase family
WL1483_RS17310	COG2801	Transposase and inactivated derivatives
WL1483_RS17315	COG0154	amidase activity
WL1483_RS17320	COG2957	Belongs to the agmatine deiminase family
WL1483_RS17335	COG1902	pentaerythritol trinitrate reductase activity
WL1483_RS17340	COG0456	acetyltransferase
WL1483_RS17345	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
WL1483_RS17360	COG0714	Associated with various cellular activities
WL1483_RS17370	COG0456	acetyltransferase
WL1483_RS17380	COG1022	Amp-dependent synthetase and ligase
WL1483_RS17385	COG2918	glutathione biosynthetic process
WL1483_RS17395	COG1238	metal cluster binding
WL1483_RS17445	COG0312	modulator of DNA gyrase
WL1483_RS17450	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
WL1483_RS17465	COG1530	ribonuclease E activity
WL1483_RS17470	COG0424	maF-like protein
WL1483_RS17475	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
WL1483_RS17480	COG1792	Involved in formation and maintenance of cell shape
WL1483_RS17485	COG1077	Cell shape determining protein MreB Mrl
WL1483_RS17530	COG1459	type II secretion system
WL1483_RS17535	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WL1483_RS17545	COG3409	Peptidoglycan-binding domain 1 protein
WL1483_RS17545	COG3267	Type II secretory pathway component ExeA
WL1483_RS17585	COG2200	EAL domain
WL1483_RS17585	COG2199	diguanylate cyclase activity
WL1483_RS17595	COG1388	LysM domain
WL1483_RS17595	COG0741	lytic transglycosylase activity
WL1483_RS17610	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
WL1483_RS17615	COG1191	sigma factor activity
WL1483_RS17645	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
WL1483_RS17660	COG4786	Flagellar basal body rod
WL1483_RS17670	COG1706	bacterial-type flagellum-dependent cell motility
WL1483_RS17675	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
WL1483_RS17680	COG4786	Flagellar basal body rod
WL1483_RS17690	COG1749	Flagellar hook protein flgE
WL1483_RS17700	COG1558	bacterial-type flagellum-dependent cell motility
WL1483_RS17705	COG1815	bacterial-type flagellum-dependent cell motility
WL1483_RS17740	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
WL1483_RS17750	COG1677	Flagellar hook-basal body complex protein FliE
WL1483_RS17775	COG1987	bacterial-type flagellum assembly
WL1483_RS17815	COG2816	NAD+ diphosphatase activity
WL1483_RS17830	COG2964	Protein conserved in bacteria
WL1483_RS17845	COG0446	pyridine nucleotide-disulphide oxidoreductase
WL1483_RS17850	COG2076	Multidrug Resistance protein
WL1483_RS17855	COG2076	Multidrug Resistance protein
WL1483_RS17860	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
WL1483_RS17865	COG0726	polysaccharide deacetylase
WL1483_RS17870	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WL1483_RS17870	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
WL1483_RS17875	COG0463	Glycosyl transferase, family 2
WL1483_RS17880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
WL1483_RS17900	COG3385	transposase activity
WL1483_RS17915	COG3385	transposase activity
WL1483_RS17920	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
WL1483_RS17925	COG0564	pseudouridine synthase activity
WL1483_RS17935	COG0542	response to heat
WL1483_RS17940	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
WL1483_RS17945	COG0542	response to heat
WL1483_RS17955	COG3240	lipase activity
WL1483_RS17960	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
WL1483_RS17960	COG2885	chlorophyll binding
WL1483_RS17970	COG3008	intermembrane lipid transfer
WL1483_RS17970	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
WL1483_RS17975	COG2995	paraquat-inducible protein a
WL1483_RS17990	COG2203	Gaf domain
WL1483_RS17990	COG5001	Diguanylate cyclase
WL1483_RS17990	COG4251	negative regulation of phosphorylation
WL1483_RS17990	COG3706	GGDEF domain
WL1483_RS17995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
WL1483_RS18000	COG2813	Specifically methylates the guanine in position
WL1483_RS18005	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
WL1483_RS18010	COG0297	glycogen (starch) synthase activity
WL1483_RS18045	COG1757	Na H antiporter
WL1483_RS18080	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
WL1483_RS18085	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
WL1483_RS18090	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
WL1483_RS18100	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WL1483_RS18105	COG0084	hydrolase, TatD family'
WL1483_RS18110	COG2165	general secretion pathway protein
WL1483_RS18120	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
WL1483_RS18125	COG4974	Belongs to the 'phage' integrase family
WL1483_RS18140	COG3620	sequence-specific DNA binding
WL1483_RS18215	COG4695	Portal protein
WL1483_RS18340	COG4974	Belongs to the 'phage' integrase family
WL1483_RS18350	COG2932	Transcriptional regulator
WL1483_RS18425	COG4695	Portal protein
WL1483_RS18565	COG0795	lipopolysaccharide-transporting ATPase activity
WL1483_RS18570	COG0795	lipopolysaccharide-transporting ATPase activity
WL1483_RS18575	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
WL1483_RS18580	COG2927	DNA polymerase III (CHI subunit)
WL1483_RS18585	COG0525	valine-tRNA ligase activity
WL1483_RS18590	COG1253	flavin adenine dinucleotide binding
WL1483_RS18595	COG0586	Pfam SNARE associated Golgi protein
WL1483_RS18600	COG1686	Belongs to the peptidase S11 family
WL1483_RS18640	COG1444	tRNA N-acetyltransferase activity
WL1483_RS18645	COG0784	Response regulator, receiver
WL1483_RS18645	COG0835	chemotaxis
WL1483_RS18650	COG0516	GMP reductase activity
WL1483_RS18660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
WL1483_RS18675	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
WL1483_RS18680	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
WL1483_RS18685	COG3178	'Phosphotransferase
WL1483_RS18690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
WL1483_RS18700	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
WL1483_RS18705	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
WL1483_RS18710	COG2967	ApaG domain
WL1483_RS18715	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WL1483_RS18725	COG3610	response to peptide
WL1483_RS18730	COG2966	Psort location CytoplasmicMembrane, score
WL1483_RS18735	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
WL1483_RS18740	COG0211	Belongs to the bacterial ribosomal protein bL27 family
WL1483_RS18745	COG0261	This protein binds to 23S rRNA in the presence of protein L20
WL1483_RS18750	COG0142	geranyltranstransferase activity
WL1483_RS18755	COG3242	Uncharacterized protein conserved in bacteria (DUF2065)
WL1483_RS18760	COG0330	HflC and HflK could
WL1483_RS18765	COG0330	HflC and HflK could
WL1483_RS18770	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
WL1483_RS18775	COG1923	regulation of RNA biosynthetic process
WL1483_RS18780	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
WL1483_RS18785	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
WL1483_RS18790	COG0860	N-Acetylmuramoyl-L-alanine amidase
WL1483_RS18795	COG0802	atpase or kinase
WL1483_RS18800	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
WL1483_RS18800	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
WL1483_RS18845	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
WL1483_RS18850	COG1162	GTPase activity
WL1483_RS18860	COG4628	conserved protein (DUF2132)
WL1483_RS18885	COG5001	Diguanylate cyclase
WL1483_RS18890	COG3076	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome
WL1483_RS18905	COG0673	inositol 2-dehydrogenase activity
WL1483_RS18915	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
WL1483_RS18925	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
WL1483_RS18930	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WL1483_RS18935	COG0789	Transcriptional regulator
WL1483_RS18940	COG0138	bifunctional purine biosynthesis protein purh
WL1483_RS18945	COG0151	Belongs to the GarS family
WL1483_RS18950	COG2233	PERMEase
WL1483_RS18955	COG0300	oxidoreductase activity
WL1483_RS18970	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
WL1483_RS18975	COG0358	DNA primase activity
WL1483_RS18980	COG1610	YqeY-like protein
WL1483_RS18985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
WL1483_RS18990	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
WL1483_RS19015	COG1132	(ABC) transporter
WL1483_RS19025	COG2897	thiosulfate sulfurtransferase activity
WL1483_RS19030	COG2066	Belongs to the glutaminase family
WL1483_RS19035	COG3171	Protein conserved in bacteria
WL1483_RS19040	COG0220	tRNA (guanine-N7-)-methyltransferase activity
WL1483_RS19050	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
WL1483_RS19055	COG0440	acetolactate synthase activity
WL1483_RS19060	COG0028	Belongs to the TPP enzyme family
WL1483_RS19080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
WL1483_RS19085	COG0473	3-isopropylmalate dehydrogenase activity
WL1483_RS19090	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
WL1483_RS19095	COG0066	3-isopropylmalate dehydratase activity
WL1483_RS19110	COG4143	(ABC) transporter
WL1483_RS19115	COG1178	ABC-type Fe3 transport system permease component
WL1483_RS19120	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
WL1483_RS19125	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
WL1483_RS19135	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
WL1483_RS19170	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
WL1483_RS19175	COG0564	pseudouridine synthase activity
WL1483_RS19185	COG0459	protein refolding
WL1483_RS19190	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
WL1483_RS19195	COG0534	Mate efflux family protein
WL1483_RS19205	COG1027	Aspartate ammonia-lyase
WL1483_RS19210	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
WL1483_RS19220	COG0477	Major facilitator Superfamily
WL1483_RS19230	COG3227	Zinc metalloprotease (Elastase)
WL1483_RS19240	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
WL1483_RS19250	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WL1483_RS19250	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
WL1483_RS19250	COG0506	proline dehydrogenase activity
WL1483_RS19255	COG4991	sh3 domain protein
WL1483_RS19260	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
WL1483_RS19270	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
WL1483_RS19280	COG1349	DNA-binding transcription factor activity
WL1483_RS19290	COG0737	Belongs to the 5'-nucleotidase family
WL1483_RS19295	COG1280	lysine exporter protein (LysE YggA)
WL1483_RS19315	COG0110	maltose O-acetyltransferase activity
WL1483_RS19340	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
WL1483_RS19345	COG2022	thiamine diphosphate biosynthetic process
WL1483_RS19355	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
WL1483_RS19360	COG0352	thiamine-phosphate diphosphorylase activity
WL1483_RS19365	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
WL1483_RS19370	COG0754	glutathionylspermidine amidase activity
WL1483_RS19380	COG3766	membrane
WL1483_RS19410	COG0745	RESPONSE REGULATOR receiver
WL1483_RS19420	COG3174	membrane
WL1483_RS19425	COG0110	maltose O-acetyltransferase activity
WL1483_RS19440	COG3845	ABC transporter
WL1483_RS19445	COG4603	Belongs to the binding-protein-dependent transport system permease family
WL1483_RS19455	COG0218	Necessary for normal cell division and for the maintenance of normal septation
WL1483_RS19465	COG1058	Belongs to the CinA family
WL1483_RS19465	COG1546	Belongs to the CinA family
WL1483_RS19475	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
WL1483_RS19480	COG1490	D-aminoacyl-tRNA deacylase activity
WL1483_RS19490	COG0456	acetyltransferase
WL1483_RS19500	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
WL1483_RS19505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
WL1483_RS19510	COG2610	gluconate transmembrane transporter activity
WL1483_RS19515	COG3265	gluconokinase activity
WL1483_RS19520	COG0129	dihydroxy-acid dehydratase activity
WL1483_RS19525	COG0800	Aldolase
WL1483_RS19530	COG1609	Transcriptional regulator
WL1483_RS19535	COG0004	ammonium transporteR
WL1483_RS19540	COG4942	peptidase
WL1483_RS19545	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
WL1483_RS19550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
WL1483_RS19555	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
WL1483_RS19560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
WL1483_RS19565	COG0316	Belongs to the HesB IscA family
WL1483_RS19565	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
WL1483_RS19575	COG0596	Alpha beta hydrolase
WL1483_RS19600	COG2873	o-acetylhomoserine
WL1483_RS19610	COG1979	alcohol dehydrogenase
WL1483_RS19630	COG1285	pathogenesis
WL1483_RS19635	COG0635	Involved in the biosynthesis of porphyrin-containing compound
WL1483_RS19645	COG3078	GTPase activator activity
WL1483_RS19655	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
WL1483_RS19660	COG0408	coproporphyrinogen oxidase activity
WL1483_RS19665	COG0009	L-threonylcarbamoyladenylate synthase
WL1483_RS19670	COG0551	DNA topoisomerase type I activity
WL1483_RS19675	COG2922	Belongs to the Smg family
WL1483_RS19680	COG0758	DNA mediated transformation
WL1483_RS19685	COG1652	LysM domain
WL1483_RS19690	COG0242	peptide deformylase activity
WL1483_RS19695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
WL1483_RS19700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
WL1483_RS19700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
WL1483_RS19705	COG0569	domain protein
WL1483_RS19710	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WL1483_RS19725	COG2221	Nitrite and sulphite reductase 4Fe-4S
WL1483_RS19725	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
WL1483_RS19730	COG1959	2 iron, 2 sulfur cluster binding
WL1483_RS19735	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
WL1483_RS19740	COG0583	DNA-binding transcription factor activity
WL1483_RS19745	COG0519	Catalyzes the synthesis of GMP from XMP
WL1483_RS19745	COG0518	GMP synthase (glutamine-hydrolyzing) activity
WL1483_RS19755	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
WL1483_RS19760	COG1396	sequence-specific DNA binding
WL1483_RS19765	COG1012	belongs to the aldehyde dehydrogenase family
WL1483_RS19805	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
WL1483_RS19815	COG2116	formate transmembrane transporter activity
WL1483_RS19820	COG1648	precorrin-2 dehydrogenase activity
WL1483_RS19820	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
WL1483_RS19825	COG2239	Acts as a magnesium transporter
WL1483_RS19835	COG3706	GGDEF domain
WL1483_RS19840	COG1368	sulfuric ester hydrolase activity
WL1483_RS19870	COG1671	Belongs to the UPF0178 family
WL1483_RS19875	COG1988	membrane-bound metal-dependent
WL1483_RS19880	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
WL1483_RS19900	COG1683	Conserved Protein
WL1483_RS19905	COG0204	Acyl-transferase
WL1483_RS19910	COG0204	Acyl-transferase
WL1483_RS19925	COG3978	acetolactate synthase activity
WL1483_RS19935	COG0129	dihydroxy-acid dehydratase activity
WL1483_RS19950	COG1309	transcriptional regulator
WL1483_RS19965	COG2801	Transposase and inactivated derivatives
WL1483_RS19995	COG0189	ligase activity
WL1483_RS20010	COG1218	3'(2'),5'-bisphosphate nucleotidase
WL1483_RS20015	COG0494	nUDIX hydrolase
WL1483_RS20020	COG1011	Hydrolase
WL1483_RS20025	COG1280	lysine exporter protein (LysE YggA)
WL1483_RS20040	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
WL1483_RS20055	COG3149	Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins
WL1483_RS20065	COG3156	type II secretion system protein K
WL1483_RS20070	COG4795	General secretion pathway protein
WL1483_RS20075	COG2165	general secretion pathway protein
WL1483_RS20085	COG2165	general secretion pathway protein
WL1483_RS20090	COG1459	type II secretion system
WL1483_RS20095	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
WL1483_RS20115	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
WL1483_RS20120	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
WL1483_RS20125	COG2205	protein histidine kinase activity
WL1483_RS20140	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
WL1483_RS20145	COG2183	response to ionizing radiation
WL1483_RS20150	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
WL1483_RS20155	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
WL1483_RS20165	COG3084	Protein conserved in bacteria
WL1483_RS20170	COG5001	Diguanylate cyclase
WL1483_RS20170	COG4251	negative regulation of phosphorylation
WL1483_RS20170	COG3706	GGDEF domain
WL1483_RS20170	COG2203	Gaf domain
WL1483_RS20180	COG2217	Heavy metal translocating P-type atpase
WL1483_RS20190	COG0166	Belongs to the GPI family
WL1483_RS20245	COG0210	DNA helicase
WL1483_RS20250	COG1289	transmembrane transporter activity
WL1483_RS20255	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
WL1483_RS20285	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
WL1483_RS20290	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
WL1483_RS20325	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
WL1483_RS20330	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WL1483_RS20330	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
WL1483_RS20335	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
WL1483_RS20340	COG3074	FtsZ-dependent cytokinesis
WL1483_RS20350	COG1045	serine acetyltransferase
WL1483_RS20355	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
WL1483_RS20360	COG0745	RESPONSE REGULATOR receiver
WL1483_RS20365	COG2205	protein histidine kinase activity
WL1483_RS20370	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
WL1483_RS20375	COG0534	Mate efflux family protein
WL1483_RS20380	COG2932	Transcriptional regulator
WL1483_RS20385	COG3423	Transcriptional regulator
WL1483_RS20390	COG2801	Transposase and inactivated derivatives
WL1483_RS20400	COG2842	Transposition protein
WL1483_RS20500	COG4384	Bacteriophage Mu Gp45 protein
WL1483_RS20510	COG3299	homolog of phage Mu protein gp47
WL1483_RS20515	COG3778	Protein conserved in bacteria
WL1483_RS20520	COG5301	cellulose 1,4-beta-cellobiosidase activity
WL1483_RS20540	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
WL1483_RS20550	COG3714	YhhN family
WL1483_RS20555	COG0742	ribosomal rna small subunit methyltransferase
WL1483_RS20560	COG5001	Diguanylate cyclase
WL1483_RS20575	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
WL1483_RS20585	COG0084	hydrolase, TatD family'
WL1483_RS20590	COG0805	protein transport
WL1483_RS20595	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
WL1483_RS20605	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
WL1483_RS20610	COG3165	ubiquinone biosynthetic process from chorismate
WL1483_RS20615	COG2226	methyltransferase
WL1483_RS20620	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
WL1483_RS20625	COG0402	S-adenosylhomocysteine deaminase activity
WL1483_RS20630	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
WL1483_RS20675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WL1483_RS20680	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
WL1483_RS20685	COG0049	tRNA binding
WL1483_RS20695	COG2168	tRNA wobble position uridine thiolation
WL1483_RS20705	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
WL1483_RS20710	COG0251	oxidation-reduction process
WL1483_RS20715	COG2964	Protein conserved in bacteria
WL1483_RS20720	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
WL1483_RS20725	COG0085	RNA polymerase activity
WL1483_RS20735	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
WL1483_RS20740	COG0081	regulation of translation
WL1483_RS20745	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
WL1483_RS20750	COG0250	Participates in transcription elongation, termination and antitermination
WL1483_RS20765	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
WL1483_RS20785	COG1072	(Pantothenic acid kinase))
WL1483_RS20790	COG2056	Na+-H+ antiporter family
WL1483_RS20800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
WL1483_RS20805	COG0569	domain protein
WL1483_RS20810	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
WL1483_RS20815	COG2207	Transcriptional regulator
WL1483_RS20840	COG4191	Histidine kinase
WL1483_RS20860	COG4221	oxidoreductase activity
WL1483_RS20875	COG1288	antiporter activity
WL1483_RS20880	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
WL1483_RS20955	COG3977	Valine--pyruvate aminotransferase
WL1483_RS20960	COG0071	Belongs to the small heat shock protein (HSP20) family
WL1483_RS20965	COG0071	Belongs to the small heat shock protein (HSP20) family
WL1483_RS20970	COG0318	PFAM AMP-dependent synthetase and ligase
WL1483_RS20975	COG2801	Transposase and inactivated derivatives
WL1483_RS20985	COG2801	Transposase and inactivated derivatives
WL1483_RS21020	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
WL1483_RS21030	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
WL1483_RS21055	COG0425	Belongs to the sulfur carrier protein TusA family
WL1483_RS21060	COG0251	oxidation-reduction process
WL1483_RS21065	COG1770	oligopeptidase
WL1483_RS21080	COG2249	NAD(P)H dehydrogenase (quinone) activity
WL1483_RS21105	COG0583	DNA-binding transcription factor activity
WL1483_RS21115	COG2258	MOSC domain
WL1483_RS21120	COG1177	transmembrane transport
WL1483_RS21125	COG1176	ABC-type spermidine putrescine transport system, permease component I
WL1483_RS21130	COG3842	ATPase activity
WL1483_RS21150	COG0174	glutamine synthetase
WL1483_RS21170	COG3045	CreA protein
WL1483_RS21175	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
WL1483_RS21180	COG0443	Heat shock 70 kDa protein
WL1483_RS21200	COG0463	Glycosyl transferase, family 2
WL1483_RS21205	COG0859	PFAM glycosyl transferase family 9
WL1483_RS21210	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
WL1483_RS21215	COG2990	Protein conserved in bacteria
WL1483_RS21220	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
WL1483_RS21230	COG0267	Belongs to the bacterial ribosomal protein bL33 family
WL1483_RS21235	COG0227	Belongs to the bacterial ribosomal protein bL28 family
WL1483_RS21240	COG2003	Belongs to the UPF0758 family
WL1483_RS21245	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
WL1483_RS21250	COG0756	dUTP diphosphatase activity
WL1483_RS21255	COG1309	transcriptional regulator
WL1483_RS21260	COG0668	transmembrane transport
WL1483_RS21285	COG2960	long-chain fatty acid transporting porin activity
WL1483_RS21300	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
WL1483_RS21315	COG3118	belongs to the thioredoxin family
WL1483_RS21320	COG0513	Belongs to the DEAD box helicase family
WL1483_RS21325	COG0248	Ppx GppA phosphatase
WL1483_RS21340	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
WL1483_RS21350	COG1561	YicC-like family, N-terminal region
WL1483_RS21355	COG0745	RESPONSE REGULATOR receiver
WL1483_RS21360	COG2205	protein histidine kinase activity
WL1483_RS21370	COG4452	Inner membrane protein CreD
WL1483_RS21375	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
WL1483_RS21380	COG0355	proton-transporting ATP synthase activity, rotational mechanism
WL1483_RS21385	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
WL1483_RS21390	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
WL1483_RS21395	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
WL1483_RS21400	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
WL1483_RS21405	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
WL1483_RS21415	COG0356	it plays a direct role in the translocation of protons across the membrane
WL1483_RS21425	COG1475	DNA binding
WL1483_RS21430	COG1192	Involved in chromosome partitioning
WL1483_RS21435	COG0357	Ribosomal RNA small subunit methyltransferase G